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Sample records for acoustic dispensing technology

  1. Smart DNA Fabrication Using Sound Waves: Applying Acoustic Dispensing Technologies to Synthetic Biology.

    Kanigowska, Paulina; Shen, Yue; Zheng, Yijing; Rosser, Susan; Cai, Yizhi

    2016-02-01

    Acoustic droplet ejection (ADE) technology uses focused acoustic energy to transfer nanoliter-scale liquid droplets with high precision and accuracy. This noncontact, tipless, low-volume dispensing technology minimizes the possibility of cross-contamination and potentially reduces the costs of reagents and consumables. To date, acoustic dispensers have mainly been used in screening libraries of compounds. In this paper, we describe the first application of this powerful technology to the rapidly developing field of synthetic biology, for DNA synthesis and assembly at the nanoliter scale using a Labcyte Echo 550 acoustic dispenser. We were able to successfully downscale PCRs and the popular one-pot DNA assembly methods, Golden Gate and Gibson assemblies, from the microliter to the nanoliter scale with high assembly efficiency, which effectively cut the reagent cost by 20- to 100-fold. We envision that acoustic dispensing will become an instrumental technology in synthetic biology, in particular in the era of DNA foundries. PMID:26163567

  2. Methods and systems for integrating fluid dispensing technology with stereolithography

    Medina, Francisco (El Paso, TX); Wicker, Ryan (El Paso, TX); Palmer, Jeremy A. (Albuquerque, NM); Davis, Don W. (Albuquerque, NM); Chavez, Bart D. (Albuquerque, NM); Gallegos, Phillip L. (Albuquerque, NM)

    2010-02-09

    An integrated system and method of integrating fluid dispensing technologies (e.g., direct-write (DW)) with rapid prototyping (RP) technologies (e.g., stereolithography (SL)) without part registration comprising: an SL apparatus and a fluid dispensing apparatus further comprising a translation mechanism adapted to translate the fluid dispensing apparatus along the Z-, Y- and Z-axes. The fluid dispensing apparatus comprises: a pressurized fluid container; a valve mechanism adapted to control the flow of fluid from the pressurized fluid container; and a dispensing nozzle adapted to deposit the fluid in a desired location. To aid in calibration, the integrated system includes a laser sensor and a mechanical switch. The method further comprises building a second part layer on top of the fluid deposits and optionally accommodating multi-layered circuitry by incorporating a connector trace. Thus, the present invention is capable of efficiently building single and multi-material SL fabricated parts embedded with complex three-dimensional circuitry using DW.

  3. Effect of holed reflector on acoustic radiation force in noncontact ultrasonic dispensing of small droplets

    Tanaka, Hiroki; Wada, Yuji; Mizuno, Yosuke; Nakamura, Kentaro

    2016-06-01

    We investigated the fundamental aspects of droplet dispensing, which is an important procedure in the noncontact ultrasonic manipulation of droplets in air. A holed reflector was used to dispense a droplet from a 27.4 kHz standing-wave acoustic field to a well. First, the relationship between the hole diameter of the reflector and the acoustic radiation force acting on a levitated droplet was clarified by calculating the acoustic impedance of the point just above the hole. When the hole diameter was half of (or equal to) the acoustic wavelength λ, the acoustic radiation force was ∼80% (or 50%) of that without a hole. The maximal diameters of droplets levitated above the holes through flat and half-cylindrical reflectors were then experimentally investigated. For instance, with the half-cylindrical reflector, the maximal diameter was 5.0 mm for a hole diameter of 6.0 mm, and droplets were levitatable up to a hole diameter of 12 mm (∼λ).

  4. Unlocking the Potential of High-Throughput Drug Combination Assays Using Acoustic Dispensing.

    Chan, Grace Ka Yan; Wilson, Stacy; Schmidt, Stephen; Moffat, John G

    2016-02-01

    Assessment of synergistic effects of drug combinations in vitro is a critical part of anticancer drug research. However, the complexities of dosing and analyzing two drugs over the appropriate range of doses have generally led to compromises in experimental design that restrict the quality and robustness of the data. In particular, the use of a single dose response of combined drugs, rather than a full two-way matrix of varying doses, has predominated in higher-throughput studies. Acoustic dispensing unlocks the potential of high-throughput dose matrix analysis. We have developed acoustic dispensing protocols that enable compound synergy assays in a 384-well format. This experimental design is considerably more efficient and flexible with respect to time, reagent usage, and labware than is achievable using traditional serial-dilution approaches. Data analysis tools integrated in Genedata Screener were used to efficiently deconvolute the combination compound mapping scheme and calculate compound potency and synergy metrics. We have applied this workflow to evaluate interactions among drugs targeting different nodes of the mitogen-activated protein kinase pathway in a panel of cancer cell lines. PMID:26160862

  5. Implementation and development of an automated, ultra-high-capacity, acoustic, flexible dispensing platform for assay-ready plate delivery.

    Griffith, Dylan; Northwood, Roger; Owen, Paul; Simkiss, Ellen; Brierley, Andrew; Cross, Kevin; Slaney, Andrew; Davis, Miranda; Bath, Colin

    2012-10-01

    Compound management faces the daily challenge of providing high-quality samples to drug discovery. The advent of new screening technologies has seen demand for liquid samples move toward nanoliter ranges, dispensed by contactless acoustic droplet ejection. Within AstraZeneca, a totally integrated assay-ready plate production platform has been created to fully exploit the advantages of this technology. This enables compound management to efficiently deliver large throughputs demanded by high-throughput screening while maintaining regular delivery of smaller numbers of compounds in varying plate formats for cellular or biochemical concentration-response curves in support of hit and lead optimization (structure-activity relationship screening). The automation solution, CODA, has the capability to deliver compounds on demand for single- and multiple-concentration ranges, in batch sizes ranging from 1 sample to 2 million samples, integrating seamlessly into local compound and test management systems. The software handles compound orders intelligently, grouping test requests together dependent on output plate type and serial dilution ranges so that source compound vessels are shared among numerous tests, ensuring conservation of sample, reduced labware and costs, and efficiency of work cell logistics. We describe the development of CODA to address the customer demand, challenges experienced, learning made, and subsequent enhancements. PMID:22922543

  6. Acoustic Separation Technology; FINAL

    Today's restrictive environmental regulations encourage paper mills to close their water systems. Closed water systems increase the level of contaminants significantly. Accumulations of solid suspensions are detrimental to both the papermaking process and the final products. To remove these solids, technologies such as flotation using dissolved air (DAF), centrifuging, and screening have been developed. Dissolved Air Flotation systems are commonly used to clarify whitewater. These passive systems use high pressure to dissolve air into whitewater. When the pressure is released, air micro-bubbles form and attach themselves to fibers and particles, which then float to the surface where they are mechanically skimmed off. There is an economic incentive to explore alternatives to the DAF technology to drive down the cost of whitewater processing and minimize the use of chemicals. The installed capital cost for a DAF system is significant and a typical DAF system takes up considerable space. An alternative approach, which is the subject of this project, involves a dual method combining the advantages of chemical flocculation and in-line ultrasonic clarification to efficiently remove flocculated contaminants from a water stream

  7. Acoustic engineering and technology '90

    Acoustic monitoring, testing and diagnosis in machines, production processes and products enhance the uptimes and profitability of machinery and plants. 18 papers discuss the current state of the art of acoustic monitoring systems including integrated factory planning as well as industrial health, and noise protection. (DG)

  8. Polymer dispensing and embossing technology for the lens type LED packaging

    This study presents a ring-type micro-structure design on the substrate and its corresponding micro fabrication processes for a lens-type light-emitting diode (LED) package. The dome-type or crater-type silicone lenses are achieved by a dispensing and embossing process rather than a molding process. Silicone with a high viscosity and thixotropy index is used as the encapsulant material. The ring-type micro structure is adopted to confine the dispensed silicone encapsulant so as to form the packaged lens. With the architecture and process described, this LED package technology herein has three merits: (1) the flexibility of lens-type LED package designs is enhanced; (2) a dome-type package design is used to enhance the intensity; (3) a crater-type package design is used to enhance the view angle. Measurement results show the ratio between the lens height and lens radius can vary from 0.4 to 1 by changing the volume of dispensed silicone. The view angles of dome-type and crater-type packages can reach 155° ± 5° and 175° ± 5°, respectively. As compared with the commercial plastic leaded chip carrier-type package, the luminous flux of a monochromatic blue light LED is improved by 15% by the dome-type package (improved by 7% by the crater-type package) and the luminous flux of a white light LED is improved by 25% by the dome-type package (improved by 13% by the crater-type package). The luminous flux of monochromatic blue light LED and white light LED are respectively improved by 8% and 12% by the dome-type package as compare with the crater-type package. (paper)

  9. Acoustically enhanced remediation, Phase 2: Technology scaling

    Iovenitti, J.L.; Hill, D.G. [Weiss Associates, Emeryville, CA (United States); Rynne, T.M.; Spadaro, J.F.; Hutchinson, W. [Scientific Applications and Research Associates, Inc., Huntington Beach, CA (United States); Illangasakere, T. [Colorado Univ., Boulder, CO (United States). Dept. of Civil, Environmental, and Architectural Engineering

    1996-12-31

    Weiss Associates is conducting the following three phase program investigating the in-situ application of acoustically enhanced remediation (AER) of contaminated unconsolidated soil and ground water under both saturated and unsaturated conditions: Phase I-- laboratory scale parametric investigation; Phase II--technology Scaling; and Phase III--large scale field tests. AER addresses the need for NAPL (either lighter or denser than water: LNAPL or DNAPL, respectively) in high and low permeability sediments, and the remediation of other types of subsurface contaminants (e.g., metals, radionuclides) in low permeability soils. This program has been placed in the U.S. Department of Energy`s (DOE`s) DNAPL product. Phase I indicated that AER could be used to effectively remediate NAPL in high permeability soil, and that removal of NAPL from low permeability soil could be increased since the water flux through these soils was significantly increased. Phase II, Technology Scaling, the subject of this paper, focused on (1) evaluating the characteristics of an AER field deployment system, (2) developing DNAPL flow and transport performance data under acoustic excitation, (3) predicting the effect of acoustic remediation in three-dimensional unconsolidated hydrogeologic conditions, (4) conducting an engineering analysis of acoustical sources, and (5) identifying candidate field site(s) for large-scale field testing of the technology.

  10. Investigation of thermal degradation with extrusion-based dispensing modules for 3D bioprinting technology.

    Lee, Hyungseok; Yoo, James J; Kang, Hyun-Wook; Cho, Dong-Woo

    2016-03-01

    Recently, numerous three-dimensional (3D) bioprinting systems have been introduced for the artificial regeneration of tissues. Among them, the extrusion-based dispensing module is the most widely used because of the processability it gives various biomaterials. The module uses high forces and temperature to dispense materials through a micro-nozzle. Generally, the harsh conditions induce thermal degradation of the material in the dispensing procedure. The thermal degradation affects the properties of the materials, and the change of the properties should be carefully controlled, because it severely affects the regeneration of tissues. Therefore, in this research, the relationship between the dispensing module and the thermal degradation of material was investigated. Extrusion-based dispensing modules can be divided into the syringe type (ST) and filament type (FT) based on working principles. We prepared a poly lactic-co-glycolic acid (PLGA) scaffold with the two methods at various time points. Then, the characteristics of the printed scaffolds were assessed by measuring molecular weight (M w), glass transition temperature (T g), in vitro degradation, compressive modulus, and cytocompatibility. The results showed that the PLGA scaffold with the FT dispensing module maintained its properties regardless of printing time points. In contrast, severe thermal degradation was observed in the scaffold group prepared by the ST dispensing module. Consequentially, it was obvious that the FT dispensing module was more suitable for producing scaffolds without severe thermal degradation. PMID:26844711

  11. Advanced Technology MEMS-based Acoustic Array Project

    National Aeronautics and Space Administration — The Interdisciplinary Consulting Corporation proposes a technological advancement of current state-of-the-art acoustic energy harvester for harsh environment...

  12. Design, microfabrication, and characterization of a moulded PDMS/SU-8 inkjet dispenser for a Lab-on-a-Printer platform technology with disposable microfluidic chip.

    Bsoul, Anas; Pan, Sheng; Cretu, Edmond; Stoeber, Boris; Walus, Konrad

    2016-08-16

    In this paper, we present a disposable inkjet dispenser platform technology and demonstrate the Lab-on-a-Printer concept, an extension of the ubiquitous Lab-on-a-Chip concept, whereby microfluidic modules are directly integrated into the printhead. The concept is demonstrated here through the integration of an inkjet dispenser and a microfluidic mixer enabling control over droplet composition from a single nozzle in real-time during printing. The inkjet dispenser is based on a modular design platform that enables the low-cost microfluidic component and the more expensive actuation unit to be easily separated, allowing for the optional disposal of the former and reuse of the latter. To limit satellite droplet formation, a hydrophobic-coated and tapered micronozzle was microfabricated and integrated with the fluidics to realize the dispenser. The microfabricated devices generated droplets with diameters ranging from 150-220 μm, depending mainly on the orifice diameter, with printing rates up to 8000 droplets per second. The inkjet dispenser is capable of dispensing materials with a viscosity up to ∼19 mPa s. As a demonstration of the inkjet dispenser function and application, we have printed type I collagen seeded with human liver carcinoma cells (cell line HepG2), to form patterned biological structures. PMID:27444216

  13. Adherence with ethinylestradiol 20 µg/drospirenone 3 mg in a flexible extended regimen supported by the use of a digital tablet dispenser with or without acoustic alarm: an open-label, randomized, multicenter study

    Wiegratz I

    2015-01-01

    Full Text Available Inka Wiegratz,1,2 Jörg Elliesen,3 Anna Maria Paoletti,4 Anja Walzer,3 Bodo Kirsch3 1Kinderwunschpraxis am Goetheplatz, Frankfurt, Germany; 2MVZ Kinderwunschzentrum Wiesbaden GmbH, Wiesbaden, Germany; 3Bayer HealthCare Pharmaceuticals, Berlin, Germany; 4Clinica Ostetrica e Ginecologica, University of Cagliari, Cagliari, ItalyObjective: To evaluate the effect of a digital dispenser's acoustic alarm function on adherence to ethinylestradiol (EE 20 µg/drospirenone 3 mg in a flexible extended regimen (EE/drospirenoneFlex among women in five European countries (France, Germany, Italy, Spain, UK seeking oral contraception.Study design: Randomized, parallel-group open-label study.Methods: Women aged 18–35 years received EE/drospirenoneFlex administered in a regimen with cycle lengths of their choice with the aid of a digital pill dispenser over 1 year. In group A (N=250, the dispenser's acoustic alarm was activated (ie, acoustic alarm + visual reminder. In group B (N=249, the acoustic alarm was deactivated (ie, visual reminder only. In addition, the women recorded pill intake daily in diary cards. The primary efficacy variable was the mean delay of daily pill release after the dispenser reminded the woman to take a pill (reference time. Secondary efficacy variables included number of missed pills, contraceptive efficacy, bleeding pattern, tolerability, and user satisfaction.Results: Dispenser data showed a mean (standard deviation [SD] daily delay in pill release of 88 (126 minutes in group A vs 178 (140 minutes in group B (P<0.0001. Median (lower quartile, Q1; upper quartile, Q3 number of missed pills was 0 (0; 1 in group A vs 4 (1; 9 in group B (P<0.0001. Diary card results revealed similar trends; however, underreporting of missed pills was evident in both groups. No pregnancies were reported during 424 women-years of exposure. Across the two groups, the mean (SD EE/drospirenoneFlex cycle length was 51.0 (31.8 days with strong regional

  14. Microfluidic EmbryoSort technology: towards in flow analysis, sorting and dispensing of individual vertebrate embryos

    Fuad, Nurul M.; Wlodkowic, Donald

    2013-12-01

    The demand to reduce the numbers of laboratory animals has facilitated the emergence of surrogate models such as tests performed on zebrafish (Danio rerio) or African clawed frog's (Xenopus levis) eggs, embryos and larvae. Those two model organisms are becoming increasingly popular replacements to current adult animal testing in toxicology, ecotoxicology and also in drug discovery. Zebrafish eggs and embryos are particularly attractive for toxicological analysis due their size (diameter 1.6 mm), optical transparency, large numbers generated per fish and very straightforward husbandry. The current bottleneck in using zebrafish embryos for screening purposes is, however, a tedious manual evaluation to confirm the fertilization status and subsequent dispensing of single developing embryos to multitier plates to perform toxicity analysis. Manual procedures associated with sorting hundreds of embryos are very monotonous and as such prone to significant analytical errors due to operator's fatigue. In this work, we present a proofof- concept design of a continuous flow embryo sorter capable of analyzing, sorting and dispensing objects ranging in size from 1.5 - 2.5 mm. The prototypes were fabricated in polymethyl methacrylate (PMMA) transparent thermoplastic using infrared laser micromachining. The application of additive manufacturing processes to prototype Lab-on-a-Chip sorters using both fused deposition manufacturing (FDM) and stereolithography (SLA) were also explored. The operation of the device was based on a revolving receptacle capable of receiving, holding and positioning single fish embryos for both interrogation and subsequent sorting. The actuation of the revolving receptacle was performed using a DC motor and/or microservo motor. The system was designed to separate between fertilized (LIVE) and non-fertilized (DEAD) eggs, based on optical transparency using infrared (IR) emitters and receivers.

  15. Research in acoustic and optical wave technology

    Siegman, A. E.; Auld, B. A.; Kino, G. S.; Beasley, M. R.; Byer, R. L.

    1982-04-01

    This report summaries the research progress and activity 1 April 1981 through 31 March 1982. Specific Projects are: (81-1) Interaction of Acoustic and Optical Waves with Domains in Ferroic Fibers with Bulk Materials: (B.A. Auld); (81-2) High T Josephson Junctions & Circuits (M. R. Beasley); (81-3) Optical & Nonlinear Optical Studies of Single Crystal Fibers (R. L. Byer); (81-4) Acoustic Surface Wave Scanning of Optical Images, (G. S. Kino); (81-5) Picosecond Raman Studies of Electronic Solids (A. E. Siegman).

  16. Dispensing nano-pico droplets of ferrofluids

    Irajizad, Peyman; Farokhnia, Nazanin; Ghasemi, Hadi

    2015-11-01

    Dispensing miniature volumes of a ferrofluid is of fundamental and practical importance for diverse applications ranging from biomedical devices, optics, and self-assembly of materials. Current dispensing systems are based on microfluidics flow-focusing approaches or acoustic actuation requiring complicated structures. A simple method is presented to continuously dispense the miniature droplets from a ferrofluid reservoir. Once a jet of the ferrofluid is subjected to a constrained flux through a membrane and an inhomogeneous magnetic field, the jet experiences a curvature-driven instability and transforms to a droplet. Ferrofluid droplets in the range of 0.1-1000 nl are dispensed with tunable dispensing frequencies. A model is developed that predicts the dispensed volume of the ferrofluid droplets with an excellent agreement with the measurements.

  17. Micromachined chemical jet dispenser

    Swierkowski, S.; Ciarlo, D.

    1996-05-13

    Goal is to develop a multi-channel micromachined chemical fluid jet dispenser that is applicable to prototype tests with biological samples that demonstrate its utility for molecular biology experiments. Objective is to demonstrate a new device capable of ultrasonically ejecting droplets from 10-200 {mu}m diameter capillaries that are arranged in an array that is linear or focused. The device is based on several common fabrication procedures used in MEMS (micro electro mechanical systems) technology: piezoelectric actuators, silicon, etc.

  18. Nanoprobe NAPPA Arrays for the Nanoconductimetric Analysis of Ultra-Low-Volume Protein Samples Using Piezoelectric Liquid Dispensing Technology

    Eugenia Pechkova

    2015-03-01

    Full Text Available In the last years, the evolution and the advances of the nanobiotechnologies applied to the systematic study of proteins, namely proteomics, both structural and functional, and specifically the development of more sophisticated and largescale protein arrays, have enabled scientists to investigate protein interactions and functions with an unforeseeable precision and wealth of details. Here, we present a further advancement of our previously introduced and described Nucleic Acid Programmable Protein Arrays (NAPPA-based nanoconductometric sensor. We coupled Quartz Crystal Microbalance with Dissipation factor Monitoring (QCM_D with piezoelectric inkjet printing technology (namely, the newly developed ActivePipette, which enables to significantly reduce the volume of probe required for genes/proteins arrays. We performed a negative control (with master mix, or MM and a positive control (MM_p53 plus MDM2. We performed this experiment both in static and in flow, computing the apparent dissociation constant of p53-MDM2 complex (130 nM, in excellent agreement with the published literature. We compared the results obtained with the ActivePipette printing and dispensing technology vs. pin spotting. Without the ActivePipette, after MDM2 addition the shift in frequency (Δf was 7575 Hz and the corresponding adsorbed mass was 32.9 μg. With the ActivePipette technology, after MDM2 addition Δf was 7740 Hz and the corresponding adsorbed mass was 33.6 μg. With this experiment, we confirmed the sensing potential of our device, being able to discriminate each gene and protein as well as their interactions, showing for each one of them a unique conductance curve. Moreover, we obtained a better yield with the ActivePipette technology.

  19. Adherence with ethinylestradiol 20 μg/drospirenone 3 mg in a flexible extended regimen supported by the use of a digital tablet dispenser with or without acoustic alarm: an open-label, randomized, multicenter study

    Wiegratz, Inka; Elliesen, Jörg; Paoletti, Anna Maria; Walzer, Anja; Kirsch, Bodo

    2015-01-01

    Objective To evaluate the effect of a digital dispenser’s acoustic alarm function on adherence to ethinylestradiol (EE) 20 μg/drospirenone 3 mg in a flexible extended regimen (EE/drospirenoneFlex) among women in five European countries (France, Germany, Italy, Spain, UK) seeking oral contraception. Study design Randomized, parallel-group open-label study. Methods Women aged 18–35 years received EE/drospirenoneFlex administered in a regimen with cycle lengths of their choice with the aid of a digital pill dispenser over 1 year. In group A (N=250), the dispenser’s acoustic alarm was activated (ie, acoustic alarm + visual reminder). In group B (N=249), the acoustic alarm was deactivated (ie, visual reminder only). In addition, the women recorded pill intake daily in diary cards. The primary efficacy variable was the mean delay of daily pill release after the dispenser reminded the woman to take a pill (reference time). Secondary efficacy variables included number of missed pills, contraceptive efficacy, bleeding pattern, tolerability, and user satisfaction. Results Dispenser data showed a mean (standard deviation [SD]) daily delay in pill release of 88 (126) minutes in group A vs 178 (140) minutes in group B (P<0.0001). Median (lower quartile, Q1; upper quartile, Q3) number of missed pills was 0 (0; 1) in group A vs 4 (1; 9) in group B (P<0.0001). Diary card results revealed similar trends; however, underreporting of missed pills was evident in both groups. No pregnancies were reported during 424 women-years of exposure. Across the two groups, the mean (SD) EE/drospirenoneFlex cycle length was 51.0 (31.8) days with strong regional differences, and the mean (SD) number of bleeding/spotting days was 50.4 (33.0) days. EE/drospirenoneFlex was well tolerated, and 80% of women were satisfied with treatment. Conclusion The dispenser’s activated acoustic alarm improved adherence with daily tablet intake of EE/drospirenoneFlex, reducing missed pills. EE

  20. Advanced Medication Dispenser

    A.I. Alexan

    2013-12-01

    Full Text Available Medication dispensing is an important activity that can have major implications if done improperly. Dispensing must be done in the correct time interval, at the correct user, with the correct drug and dose. We propose a smart medication dispenser that can satisfy these needs and provide a mechanism for supervision. In order to ensure that the dispensing process is error free, the concept of a new smart medication container is used. A smart medication container is “smart” as it holds the medication dispensing parameters for the drugs it contains: dispensing time and date and name. Based on this information, the actual dispensing is done.

  1. Development of Adaptive Acoustic Impedance Control Technologies of Acoustic Duct Liner

    Hiroshi Kobayashi

    2011-01-01

    Full Text Available This paper describes the development of adaptive acoustic impedance control (AAC technologies to achieve a larger fan noise reduction, by adaptively adjusting reactance and resistance of the acoustic liner impedance. For the actual proof of the AAC technology III performance, the advanced fan noise absorption control duct liner II was made on trial basis, with the simple control system and the plain device. And, then, the duct liner II was examined for the AAC technology I, II, and III models, using the high speed fan test facility. The test results made clear that the duct liner II of the AAC technology III model could achieve the fan noise reduction higher than O.A. SPL 10 dB (A at the maximum fan speed 6000 rpm, containing the reduction of fundamental BPF tone of 18 dB and 2nd BPF tone of 10 dB in response to the fan peed change from 3000 to 6000 rpm.

  2. Transport composite fuselage technology: Impact dynamics and acoustic transmission

    Jackson, A. C.; Balena, F. J.; Labarge, W. L.; Pei, G.; Pitman, W. A.; Wittlin, G.

    1986-01-01

    A program was performed to develop and demonstrate the impact dynamics and acoustic transmission technology for a composite fuselage which meets the design requirements of a 1990 large transport aircraft without substantial weight and cost penalties. The program developed the analytical methodology for the prediction of acoustic transmission behavior of advanced composite stiffened shell structures. The methodology predicted that the interior noise level in a composite fuselage due to turbulent boundary layer will be less than in a comparable aluminum fuselage. The verification of these analyses will be performed by NASA Langley Research Center using a composite fuselage shell fabricated by filament winding. The program also developed analytical methodology for the prediction of the impact dynamics behavior of lower fuselage structure constructed with composite materials. Development tests were performed to demonstrate that the composite structure designed to the same operating load requirement can have at least the same energy absorption capability as aluminum structure.

  3. Advanced Medication Dispenser

    A. I. Alexan; A. R. Osan; Oniga, S.

    2013-01-01

    Medication dispensing is an important activity that can have major implications if done improperly. Dispensing must be done in the correct time interval, at the correct user, with the correct drug and dose. We propose a smart medication dispenser that can satisfy these needs and provide a mechanism for supervision. In order to ensure that the dispensing process is error free, the concept of a new smart medication container is used. A smart medication container is “smart” ...

  4. Tutorial on the Psychophysics and Technology of Virtual Acoustic Displays

    Wenzel, Elizabeth M.; Null, Cynthia (Technical Monitor)

    1998-01-01

    Virtual acoustics, also known as 3-D sound and auralization, is the simulation of the complex acoustic field experienced by a listener within an environment. Going beyond the simple intensity panning of normal stereo techniques, the goal is to process sounds so that they appear to come from particular locations in three-dimensional space. Although loudspeaker systems are being developed, most of the recent work focuses on using headphones for playback and is the outgrowth of earlier analog techniques. For example, in binaural recording, the sound of an orchestra playing classical music is recorded through small mics in the two "ear canals" of an anthropomorphic artificial or "dummy" head placed in the audience of a concert hall. When the recorded piece is played back over headphones, the listener passively experiences the illusion of hearing the violins on the left and the cellos on the right, along with all the associated echoes, resonances, and ambience of the original environment. Current techniques use digital signal processing to synthesize the acoustical properties that people use to localize a sound source in space. Thus, they provide the flexibility of a kind of digital dummy head, allowing a more active experience in which a listener can both design and move around or interact with a simulated acoustic environment in real time. Such simulations are being developed for a variety of application areas including architectural acoustics, advanced human-computer interfaces, telepresence and virtual reality, navigation aids for the visually-impaired, and as a test bed for psychoacoustical investigations of complex spatial cues. The tutorial will review the basic psychoacoustical cues that determine human sound localization and the techniques used to measure these cues as Head-Related Transfer Functions (HRTFs) for the purpose of synthesizing virtual acoustic environments. The only conclusive test of the adequacy of such simulations is an operational one in which

  5. Theoretical detection ranges for acoustic based manatee avoidance technology.

    Phillips, Richard; Niezrecki, Christopher; Beusse, Diedrich O

    2006-07-01

    The West Indian manatee (Trichechus manatus latirostris) has become endangered partly because of watercraft collisions in Florida's coastal waterways. To reduce the number of collisions, warning systems based upon detecting manatee vocalizations have been proposed. One aspect of the feasibility of an acoustically based warning system relies upon the distance at which a manatee vocalization is detectable. Assuming a mixed spreading model, this paper presents a theoretical analysis of the system detection capabilities operating within various background and watercraft noise conditions. This study combines measured source levels of manatee vocalizations with the modeled acoustic properties of manatee habitats to develop a method for determining the detection range and hydrophone spacing requirements for acoustic based manatee avoidance technologies. In quiet environments (background noise approximately 70 dB) it was estimated that manatee vocalizations are detectable at approximately 250 m, with a 6 dB detection threshold, In louder environments (background noise approximately 100dB) the detection range drops to 2.5 m. In a habitat with 90 dB of background noise, a passing boat with a maximum noise floor of 120 dB would be the limiting factor when it is within approximately 100 m of a hydrophone. The detection range was also found to be strongly dependent on the manatee vocalization source level. PMID:16875213

  6. Structural Acoustic Prediction and Interior Noise Control Technology

    Mathur, G. P.; Chin, C. L.; Simpson, M. A.; Lee, J. T.; Palumbo, Daniel L. (Technical Monitor)

    2001-01-01

    This report documents the results of Task 14, "Structural Acoustic Prediction and Interior Noise Control Technology". The task was to evaluate the performance of tuned foam elements (termed Smart Foam) both analytically and experimentally. Results taken from a three-dimensional finite element model of an active, tuned foam element are presented. Measurements of sound absorption and sound transmission loss were taken using the model. These results agree well with published data. Experimental performance data were taken in Boeing's Interior Noise Test Facility where 12 smart foam elements were applied to a 757 sidewall. Several configurations were tested. Noise reductions of 5-10 dB were achieved over the 200-800 Hz bandwidth of the controller. Accelerometers mounted on the panel provided a good reference for the controller. Configurations with far-field error microphones outperformed near-field cases.

  7. A Change in Dispensing Technology --Jetting Takes off%非接触式喷射点胶--未来的点胶技术

    Steven J. Adamson; David Wang

    2004-01-01

    Jetting of epoxies and other materials is going to change the way people do dispensing. For the last twenty years, dispensing has evolved from merely pushing fluid through a needle to a highly automated production process. Controlling fluid deposition, needle positioning and dispensed volume accuracy has dramatically improved in recent years. Additionally, speed has increased while software has simplified operational control. Now jet dispensing fluids has become practical and it is going to have as large an impact on the electronics assembly industry that Ink Jet printing has had in the office / home environment.

  8. Safety and Traceability in Patient Healthcare through the Integration of RFID Technology for Intravenous Mixtures in the Prescription-Validation-Elaboration-Dispensation-Administration Circuit to Day Hospital Patients.

    Martínez Pérez, María; Vázquez González, Guillermo; Dafonte, Carlos

    2016-01-01

    This work presents the integration of the RFID technology with the aim of ensuring the traceability of patients and minimization of adverse events during the process of prescription-validation-elaboration-dispensation-administration of medication by means of the implementation of various passive and active WIFI RFID systems in the Pharmacy and Day Hospital services of the Complejo Hospitalario Universitario A Coruña. Obtaining patient traceability and using the patient/drug binomial during this process allows us to minimize the occurrence of adverse events. The key points in this work are the unmistakably unique identification and accurate real time location of the controlled items (patients and medication). RFID technology has proved to be invaluable in assisting with the everyday clinical practice of a hospital, and has been successfully implemented in this environment and others. In services such as the day hospital, the implementation of said technology is further justified by the high costs of the service and the high risk to the patient. PMID:27483269

  9. Light-induced immobilisation of biomolecules as an attractive alternative to microdroplet dispensing-based arraying technologies

    Crookshanks, Meg; Skovsen, Esben; Petersen, Maria Teresa Neves;

    2007-01-01

    of reproducibility. This technology can be used to circumvent the need for often expensive nano/microdispensing technologies. The ultimate size of the immobilised spots is defined by the focal area of the UV beam, which for a diffraction-limited beam can be less than 1 mm in diameter. LIMI has the added benefit...

  10. Acoustic Energy: An Innovative Technology for Stimulating Oil Wells

    Edgar, Dorland E.; Peters, Robert W.; Johnson, Donald O.; Paulsen, P. David; Roberts, Wayne

    2006-04-30

    application of acoustic energy (sonication) significantly reduced the viscosity of crude oils, and the amount of viscosity reduction resulting is greater for more viscous, heavy crude oils than it is for less viscous, light crude oils. (2) Test results showed that after being heated, resulting viscosity reductions were not sustained following treatment to the extent that post-sonication reductions were sustained. (3) The maximum viscosity reductions in Oils 1, 2, and 3 due to sonication were 43%, 76%, and 6%, respectively. Samples of Oil 2 associated with larger viscosity reductions often exhibited a definite water separation layer follow the tests, whereas reductions of approximately 23% were measured when this separation was not observed. (4) It was observed that neither horn design nor the reduction of input power by 25% had very little effect on the ability of sonication to alter crude oil viscosity. (5) The chemical additives produced a range of viscosity reduction from 37% to a maximum of 94% with the largest reductions being facilitated by the abundant water present Oil 2. If the Oil 2 results are not considered, the maximum reduction was 73%. The effects of the additives and sonication are enhanced by each other. (6) In only one test did the viscosity return to as much as 50% of the pre-treatment value during a period of 30 days following treatment; recovery was much less in all other cases. Therefore, more than half of the viscosity reduction was maintained for a month without additional treatment. (7) Possible applications, market potential, and economic value of the implementation of a mature sonication technology within the petroleum industry were identified, and it was estimated that the potential exists that more than a billion barrels of oil could be upgraded or produced annually as a result. The project results successfully demonstrated that sonication alone and in combination with chemical additives can effectively reduce the viscosity of crude oils having a

  11. Acoustics

    Goodman, Jerry R.; Grosveld, Ferdinand

    2007-01-01

    The acoustics environment in space operations is important to maintain at manageable levels so that the crewperson can remain safe, functional, effective, and reasonably comfortable. High acoustic levels can produce temporary or permanent hearing loss, or cause other physiological symptoms such as auditory pain, headaches, discomfort, strain in the vocal cords, or fatigue. Noise is defined as undesirable sound. Excessive noise may result in psychological effects such as irritability, inability to concentrate, decrease in productivity, annoyance, errors in judgment, and distraction. A noisy environment can also result in the inability to sleep, or sleep well. Elevated noise levels can affect the ability to communicate, understand what is being said, hear what is going on in the environment, degrade crew performance and operations, and create habitability concerns. Superfluous noise emissions can also create the inability to hear alarms or other important auditory cues such as an equipment malfunctioning. Recent space flight experience, evaluations of the requirements in crew habitable areas, and lessons learned (Goodman 2003; Allen and Goodman 2003; Pilkinton 2003; Grosveld et al. 2003) show the importance of maintaining an acceptable acoustics environment. This is best accomplished by having a high-quality set of limits/requirements early in the program, the "designing in" of acoustics in the development of hardware and systems, and by monitoring, testing and verifying the levels to ensure that they are acceptable.

  12. Dispenser printed electroluminescent lamps on textiles for smart fabric applications

    de Vos, Marc; Torah, Russel; Tudor, John

    2016-04-01

    Flexible electroluminescent (EL) lamps are fabricated onto woven textiles using a novel dispenser printing process. Dispenser printing utilizes pressurized air to deposit ink onto a substrate through a syringe and nozzle. This work demonstrates the first use of this technology to fabricate EL lamps. The luminance of the dispenser printed EL lamps is compared to screen-printed EL lamps, both printed on textile, and also commercial EL lamps on polyurethane film. The dispenser printed lamps are shown to have a 1.5 times higher luminance than the best performing commercially available lamp, and have a comparable performance to the screen-printed lamps.

  13. The study of underwater acoustic communication technology based-on the acoustic vector sensor

    QIAO Gang; SANG Enfang

    2007-01-01

    Underwater acoustic (UWA) communication based on an acoustic vector sensor is studied. The method of joint weighted sound pressure and velocity processing is used in phase modulation high-speed UWA communication system combined with coherent demodulation and adaptive equalization algorithm to demodulate and decode. Whereas the sound intensity could be used instead of pressure for frequency decoding in frequency modulation UWA communication system. The results of theory analysis, simulation calculations and lake trials have shown that either in phase modulation or in frequency modulation UWA communication system, the processing gain can be evidently increased, so that the BER (bit error rate) can be effectively reduced and the telemetry distance can be enlarged by using the acoustic vector sensor.

  14. Physician drug dispensing.

    Lober, C W; Behlmer, S D; Penneys, N S; Shupack, J L; Thiers, B H

    1988-11-01

    We have reviewed the issue of physician drug dispensing by focusing upon quality of care, economic considerations, drug availability, patient compliance, safety, and increased governmental regulation. From a quality of care perspective, the increased use of pharmacist assistants, the tendency toward generic and therapeutic drug substitution, and the less specialized clinical education of pharmacists all pose hazards rather than safety checks upon physician prescribing. There is no evidence that pharmacists charge less than physicians. If they did, there would be no need to protect their incomes legislatively by restricting physician dispensing. Economic motivation per se is less important to a physician than providing a true convenience for his patients and thus encouraging a closer doctor-patient relationship. Physician dispensing adds to the availability of medication and may minimize the number of patients shuttling between pharmacies to obtain complex multi-ingredient preparations. Compliance is enhanced as availability increases. Prepackaged pharmaceuticals prepared under the auspices of pharmacists and dispensed by physicians are at least as safe as those prepared by the ungloved hands of a pharmacist hidden behind store counters. Thus, restricting the physician's right to dispense can negatively affect the quality of medical care, the cost of medications, safety, the availability of pharmaceuticals, and patient compliance. Such limitation is certainly not in the best interest of our patients. PMID:3056999

  15. Mississippi Curriculum Framework for Ophthalmic Technology (Program CIP: 51.1801--Opticianry/Dispensing Optician). Postsecondary Programs.

    Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

    This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the ophthalmic technology program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies, and section II…

  16. Improved Dispenser Cathodes

    Ives, R. Lawrence; Falce, Lou

    2006-01-01

    Variations in emission current from dispenser cathodes can be caused by variations in temperature and work function over the surface. This paper described research to reduce these variations using improved mechanical designs and controlled porosity cathodes made from sintered tungsten wires. The program goal is to reduce current emission variations to less than 5% over the surface of magnetron injection guns operating temperature limited.

  17. Stage acoustics for musicians: A multidimensional approach using 3D ambisonic technology

    Guthrie, Anne

    In this research, a method was outlined and tested for the use of 3D Ambisonic technology to inform stage acoustics research and design. Stage acoustics for musicians as a field has yet to benefit from recent advancements in auralization and spatial acoustic analysis. This research attempts to address common issues in stage acoustics: subjective requirements for performers in relation to feelings of support, quality of sound, and ease of ensemble playing in relation to measurable, objective characteristics that can be used to design better stage enclosures. While these issues have been addressed in previous work, this research attempts to use technological advancements to improve the resolution and realism of the testing and analysis procedures. Advancements include measurement of spatial impulse responses using a spherical microphone array, higher-order ambisonic encoding and playback for real-time performer auralization, high-resolution spatial beamforming for analysis of onstage impulse responses, and multidimensional scaling procedures to determine subjective musician preferences. The methodology for implementing these technologies into stage acoustics research is outlined in this document and initial observations regarding implications for stage enclosure design are proposed. This research provides a robust method for measuring and analyzing performer experiences on multiple stages without the costly and time-intensive process of physically surveying orchestras on different stages, with increased repeatability while maintaining a high level of immersive realism and spatial resolution. Along with implications for physical design, this method provides possibilities for virtual teaching and rehearsal, parametric modeling and co-located performance.

  18. An introduction to acoustic emission technology for in-process inspection of welds

    Weld quality monitoring, as it stands today, is primarily done by X-ray radiography and ultrasonic testing which is applied after welding is complete. Acoustic Emission Technique (AET) also presents a possible substitute for weld quality monitoring which can be used during welding. Acoustic signals are generated during welding and the sound waves of weld defects are picked up by using AE sensors. With the introduction of sophisticated instrumentation in AET, it is possible to carry out the test even in noisy shop floor environments. Large number of reports on the subject of acoustic emission in recent years is a clear indication that it is gaining importance in welding industry. The present day status of the acoustic emission technology as an on-line weld quality monitoring technique has been reviewed. This report discusses the technique and system along with the acoustic emission parameters important for weld quality analysis. This also deals with the application of this technique in different welding processes like TIG, resistance, electro slag and submerged arc. It has been reported that monitoring of emission during welding can detect crack formation, crack growth and lack of fusion precisely. Static defects like porosity and inclusion do not generate very strong acoustic signals and are therefore difficult to intercept, but, however, lately they have detected successfully. (author)

  19. Holy grail: Pioneering acoustic telemetry technology set to revolutionize downhole communication

    Greenaway, R.

    2003-12-01

    Acoustic telemetry, a faster and more efficient downhole-to-surface-communication technology, is the latest development in downhole communication systems. The system has been developed by Extreme Engineering Limited of Calgary, led by Derek Logan, founder and one-time senior vice-president of Ryan Energy Technologies that developed the original measurement -while-drilling (MWD) and logging-while-drilling )LWD) tools. The company predicts that acoustic telemetry will cause a massive transformation of the drilling industry in Western Canada once the technology is commercialized. Conventional MWD techniques, based on mud-pulse technology, have been industry standard since the 1970s, but mud-pulse technology is now considered extremely slow. In the 1980s industry came up electromagnetic telemetry, as an alternative to mud-pulse. Today, the need to transmit ever more data, the need for a faster communications system and greater wellbore control, has become even more pressing. Logan believes that acoustic technology is the answer. It is not only capable of transmitting data 20 to 30 times faster than mud-pulse telemetries, it can also communicate massive amounts of data. It can be used in drilling, completion production, drillstem testing, frac monitoring and any other wellbore process requiring wireless real-time telemetry. Acoustic telemetry is also the only wireless system that can perform MWD and LWD in offshore underbalanced drilling. Notwithstanding its great promise, Extreme Engineering Limited had considerable difficulty raising funds for developing and commercializing XAcT (the trade name for acoustic telemetry). Prospects are reported to have been substantially improved by recent infusion of funds by the federal Industrial Research Assistance Program (IRAP) , and XAcT's recognition by R and D Magazine with one of the R and D 100 awards for 2003. 3 figs.

  20. Communication Acoustics

    Blauert, Jens

    Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book...... the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as......: acoustics, cognitive science, speech science, and communication technology....

  1. E85 Dispenser Study

    Moriarty, K.; Johnson, C.; Sears, T.; Bergeron, P.

    2009-12-01

    This study reviews E85 dispensing infrastructure advances and issues and evaluates the geographic concentration of flexible fuel vehicles (FFVs), E85 stations, ethanol production facilities, and E85 suppliers. Costs, space, financial incentives, and barriers to adding E85 fueling equipment at existing stations are also assessed. This study found that E85 is increasingly available in the U.S. in half of the states; however, the other half have minimal or no E85 fueling options. Despite these gains, E85 is only available at 1% of U.S. gasoline stations. Ethanol production reached 9.5 billion gallons in 2008, but less than 1% is consumed as E85. FFVs have not reached a significant concentration in any county, metropolitan area, or state.

  2. Distributed Acoustic Sensing Technology in a Magmatic Geothermal Field - First Results From a Survey in Iceland

    Reinsch, Thomas; Jousset, Philippe; Henninges, Jan; Blanck, Hanna

    2016-04-01

    Seismic methods are particularly suited for investigating the Earth's subsurface. Compared to surface-measurements , wellbore measurements can be used to acquire more detailed information about rock properties and possible fluid pathways within a geothermal reservoir. For high temperature geothermal wells, however, ambient temperatures are often far above the operating temperature range of conventional geophones. One way to overcome this limitation is the application of fiber optic sensor systems, where only the passive optical fiber is subjected to downhole conditions. Their applicability is thus determined by the operating temperature range of the optical fiber. Choosing appropriate fibers, such sensor systems can be operated at temperatures far above 200°C. Along an optical fiber, the distributed acoustic sensing technology (DAS) can be used to acquire acoustic signals with a high spatial and temporal resolution. Previous experiments have shown that the DAS technology is well suited for active seismic measurements. Within the framework of the EC funded project IMAGE, a fiber optic cable was deployed in a newly drilled geothermal well (RN-34) within the Reykjanes geothermal field, Iceland. Additionally, a >15 km fiber optic cable, already available at the surface, was connected to a DAS read-out unit. Acoustic data was acquired continuously for 9 days. Hammer shots were performed at the wellhead as well as along the surface cable in order to locate individual acoustic traces and calibrate the spatial distribution of the acoustic information. During the monitoring period both signals from on- and offshore explosive sources and natural seismic events could be recorded. We compare the fiber optic data to conventional seismic records from a dense seismic network deployed on the Reykjanes in the course of the IMAGE project. Here, first results from the seismic survey will be presented.

  3. Report of the working group on fisheries acoustics science and technology (WGFAST)

    ICES

    2005-01-01

    The Working Group on Fisheries Acoustics Science and Technology (WGFAST) met at the Food and Agricultural Organisation of the United Nations in Rome, Italy, from 19–22 April 2005. David A. Demer, USA, was Chair, Alex De Robertis, USA, was Rapporteur and Jessica D. Lipsky, USA, was the Recorder. There were 83 participants from 16 countries. a ) The first topic was “Measuring underwater radiated noise from survey vessels and its effects on fish”. Quiet vessels have distinct advantages over c...

  4. Development of Acoustic Emission Technology for Condition Monitoring and Diagnosis of Rotating Machines; Bearings, Pumps, Gearboxes, Engines and Rotating Structures.

    Mba, David; Rao, Raj B. K. N.

    2006-01-01

    One of the earliest documented applications of Acoustic Emission Technology (AET) to rotating machinery monitoring was in the late 1960s. Since then there has been an explosion in research and application based studies covering bearings, pumps, gearboxes, engines and rotating structures. This paper presents a comprehensive and critical review to date on the application of Acoustic Emission Technology to condition monitoring and diagnostics of rotating machinery.

  5. Novel acoustic technology for studying free-ranging shark social behaviour by recording individuals' interactions.

    Tristan L Guttridge

    Full Text Available Group behaviours are widespread among fish but comparatively little is known about the interactions between free-ranging individuals and how these might change across different spatio-temporal scales. This is largely due to the difficulty of observing wild fish groups directly underwater over long enough time periods to quantify group structure and individual associations. Here we describe the use of a novel technology, an animal-borne acoustic proximity receiver that records close-spatial associations between free-ranging fish by detection of acoustic signals emitted from transmitters on other individuals. Validation trials, held within enclosures in the natural environment, on juvenile lemon sharks Negaprion brevirostris fitted with external receivers and transmitters, showed receivers logged interactions between individuals regularly when sharks were within 4 m ( approximately 4 body lengths of each other, but rarely when at 10 m distance. A field trial lasting 17 days with 5 juvenile lemon sharks implanted with proximity receivers showed one receiver successfully recorded association data, demonstrating this shark associated with 9 other juvenile lemon sharks on 128 occasions. This study describes the use of acoustic underwater proximity receivers to quantify interactions among wild sharks, setting the scene for new advances in understanding the social behaviours of marine animals.

  6. Pipeline integrity evaluation of oil pipelines using free-swimming acoustic technology

    Ariaratnam, Samuel T. [Arizona State University, Tempe, Arizona (United States); Chandrasekaran, Muthu [Pure Technologies Limited, Calgary, AB (Canada)

    2010-07-01

    In the United States, the Pipeline and Hazardous Materials Safety Administration (PHMSA) funded a joint academy-industry research project, which developed and refined a free-swimming tool called SmartBall. The tool swims through the pipeline and gives results at a much lower cost than current leak detection methods, and it can detect leaks as small as 0.03 gpm of oil. GPS-synchronized above-ground loggers capture acoustic signals and record the passage of the tool through the pipeline. The tool is spherical and smaller than the pipe, through which it rolls silently; it can overcome obstacles that could otherwise make a pipeline unpiggable. SmartBall uses the great potential of acoustic detection, because when a pressurized product leaks from a pipe, it produces a distinctive acoustic signal that travels through the product; at the same time, it overcomes the problem caused by the very limited range of this signal. This technology can prevent enormous economic consequences such as a 50,000-gallon gasoline spill that happened in 2003 between Tucson and Phoenix.

  7. Second Interim Report of the Working Group on Fisheries Acoustics, Science and Technology (WGFAST). 29 May 2015 Nantes, France

    ICES

    2015-01-01

    The Working Group on Fisheries Acoustic Science and Technology (WGFAST) met in Nantes, France, on 29 May 2015. Verena Trenkel, France, served as Chair. There were 43 participants who discussed the report from the linked Working Group on Target Classification (WGTC), the needs created by the increasing use of wideband acoustics and resulting potential future activities for WGFAST, the contribution to the South Pacific regional management organization (SPRFMO) initiative on calibrating echosoun...

  8. Slow Release of Plant Volatiles Using Sol-Gel Dispensers.

    Bian, L; Sun, X L; Cai, X M; Chen, Z M

    2014-12-01

    The black citrus aphid, also known as the tea aphid, (Toxoptera aurantii Boyer) attacks economically important crops, including tea (Camellia sinensis (L.) O. Kuntze). In the current study, silica sol-gel formulations were screened to find one that could carry and release C. sinensis plant volatiles to lure black citrus aphids in a greenhouse. The common plant volatile trans-2-hexen-1-al was used as a model molecule to screen for suitable sol-gel formulations. A zNose (Electronic Sensor Technology, Newbury Park, CA) transportable gas chromatograph was used to continuously monitor the volatile emissions. A sol-gel formulation containing tetramethyl orthosilicate and methyltrimethoxysilane in an 8:2 (vol:vol) ratio was selected to develop a slow-release dispenser. The half-life of trans-2-hexen-1-al in the sol-gel dispenser increased slightly with the volume of this compound in the dispenser. Ten different volatiles were tested in the sol-gel dispenser. Alcohols of 6-10 carbons had the longest half-lives (3.01-3.77 d), while esters of 6-12 carbons had the shortest (1.53-2.28 d). Release of these volatiles from the dispensers could not be detected by the zNose after 16 d (cis-3-hexenyl acetate) to 26 d (3,7-dimethylocta-1,6-dien-3-ol). In greenhouse experiments, trans-2-hexen-1-al and cis-3-hexen-1-ol released from the sol-gel dispensers attracted aphids for ≍17 d, and release of these volatiles could not be detected by the zNose after ≍24 d. The sol-gel dispensers performed adequately for the slow release of plant volatiles to trap aphids in the greenhouse. PMID:26470065

  9. Laser cleaning of steam generator tubing based on acoustic emission technology

    As a physical method, laser cleaning technology in equipment maintenance will be a good prospect. The experimental apparatus for laser cleaning of heat tubes in the steam generator was designed according to the results of theoretical analysis. There are two conclusions; one is that laser cleaning technology is attached importance to traditional methods. Which has advantages in saving on much manpower and material resource and it is a good cleaning method for heat tubes. The other is that the acoustic emission signal includes lots of information on the laser cleaning process, which can be used as real-time monitoring in laser cleaning processes. When the laser acts for 350 s, 100 % contaminants of heat tubes is cleaned off, and the sensor only receives weak AE signal at that time.

  10. Laser cleaning of steam generator tubing based on acoustic emission technology

    Hou, Su-xia; Luo, Ji-jun; Shen, Tao; Li, Ru-song [Xi' an Hi-Tech Institute, Xi' an (China)

    2015-12-15

    As a physical method, laser cleaning technology in equipment maintenance will be a good prospect. The experimental apparatus for laser cleaning of heat tubes in the steam generator was designed according to the results of theoretical analysis. There are two conclusions; one is that laser cleaning technology is attached importance to traditional methods. Which has advantages in saving on much manpower and material resource and it is a good cleaning method for heat tubes. The other is that the acoustic emission signal includes lots of information on the laser cleaning process, which can be used as real-time monitoring in laser cleaning processes. When the laser acts for 350 s, 100 % contaminants of heat tubes is cleaned off, and the sensor only receives weak AE signal at that time.

  11. Acoustical Imaging

    Litniewski, Jerzy; Kujawska, Tamara; 31st International Symposium on Acoustical Imaging

    2012-01-01

    The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place continuously since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2011 the 31st International Symposium on Acoustical Imaging was held in Warsaw, Poland, April 10-13. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 31 in the Series contains an excellent collection of papers in six major categories: Biological and Medical Imaging Physics and Mathematics of Acoustical Imaging Acoustic Microscopy Transducers and Arrays Nondestructive Evaluation and Industrial Applications Underwater Imaging

  12. Dispensing of non-prescribed antibiotics in Jordan

    Almaaytah A

    2015-09-01

    Full Text Available Ammar Almaaytah,1 Tareq L Mukattash,2 Julia Hajaj2 1Department of Pharmaceutical Technology, 2Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan Objective: Current regulations in Jordan state that antibiotics cannot be sold without a medical prescription. This study aimed to assess the percentage of pharmacies that dispense antibiotics without a medical prescription in the Kingdom of Jordan and identify and highlight the extent and seriousness of such practices among Jordanian pharmacies. Methods: A prospective study was performed, and five different clinical scenarios were simulated at pharmacies investigated including sore throat, otitis media, acute sinusitis, diarrhea, and urinary tract infection in childbearing-aged women. Three levels of demand were used to convince the pharmacists to sell an antibiotic. Results: A total of 202 total pharmacies in Jordan were visited in the present study. The majority of pharmacies (74.3% dispensed antibiotics without prescription with three different levels of demand. The percentage of pharmacies dispensing antibiotics without a prescription for the sore throat scenario was 97.6%, followed by urinary tract infection (83.3%, diarrhea (83%, and otitis media (68.4%. The lowest percentage of antibiotic dispensing was for the acute sinusitis simulation at 48.5%. Among the pharmacies that dispensed antibiotics, the pharmacists provided an explanation as the number of times per day the drug should be taken in 95.3% of the cases, explained the duration of treatment in 25.7%, and inquired about allergies prior to the sale of the antibiotic in only 17.3%. Only 52 pharmacies (25.7% refused to dispense any kind of antibiotics, the majority (61.5% of this refusal response came from acute sinusitis cases, while the minority (2.4% came from the sore throat cases. Conclusion: The results of this study demonstrate that antibiotics continue to be dispensed

  13. Applying of the array transducers' technology for surface acoustic waves materials characterization in the transient regime

    In this document we present a theoretical and experimental study which has been led to design a surface acoustic wave device for local characterisation (relatively to the wavelength) of isotropic or anisotropic materials. The device is based on a phased-array transducer of conical shape we have specifically designed for this purpose. It operates in the impulsive mode, in the frequency range of 1-5 MHz. In order to deduce mechanical properties of the material, it is possible to measure the surface wave characteristics (velocity, attenuation,...). Different methods for measuring the wave velocity have been developed taking advantage of from the phased-array technology. The originality of theses methods relies on the fact that the measures are performed without moving the transducer. Consequently, the device requires no additional mechanical system and it is quite compact. In addition, this shortens the characterisation process duration comparatively to the usually available methods (e. g. the V(z) technique). In the theoretical section of this study, a versatile model allowing to simulate in the time harmonic regime as well as in the transient regime, the transmitted field, the field reflected on isotropic or anisotropic planar samples and the output voltage for transducers of arbitrary shapes has been developed. The model has been applied to the phased-array conical transducer as well as to more classical transducers such as planar (rectangular) or focusing (spherically or cylindrically shaped) transducers. It predicts not only the geometrical contributions of the reflected field and signal but also the leaky contributions related to the surface acoustic waves. (author)

  14. Acoustic Cavitation: A Potential Remediation Technology for On-Site Elimination of Perfluorinated Contaminants

    Vecitis, C. D.; Cheng, J.; Park, H.; Hoffmann, M. R.

    2006-12-01

    Perfluorinated chemicals are emerging as globally ubiquitous contaminants which are recalcitrant to the conventional remediation techniques of adsorption and chemical oxidation. The release of these chemicals to the environment occurs from specific sites such as manufacturing plants, fire-fighting foams at airports and contaminated landfills. Even though these compounds are widely recognized as potentially hazardous, disposal regulations have been limited due to the ineffectiveness of current pump and treat technologies towards these species. We have shown that ultrasonically induced acoustic cavitation can effectively mineralize aqueous perfluorinated acid and sulfonate species by in situ pyrolysis and chemical oxidation at the lab and pilot scale. Efficiency has been tested on a variety of matrices such as tap water, groundwater and landfill pump-out with VOC content being the major detriment towards remediation. Advanced oxidation by the simultaneously application of ozone and ultrasound seems to partially eliminate this barrier by enhancing the rate of VOC mineralization. Application of this technology to a contaminated field site and the obstacles of scaling to such a degree are discussed.

  15. The Innovated Flexible Surface Acoustic Wave Devices on Fully InkJet Printing Technology

    Cha’o-Kuang Chen

    2013-09-01

    Full Text Available An innovated fabricated process of the flexible surface acoustic wave (SAW device is proposed in this study. Fully inkjet printing and sol-gel technology are used in this fabricated process. The flexible SAW device is composed of a ZnO layer sandwiched in between a flexible polyimide plastic sheet and two sets of interdigital transducers layer. The material of the top interdigital transducer layer is nano silver. The ZnO solution is prepared by sol-gel technology. Both the ZnO and top interdigital transducer layers are deposited by inkjet printing. The fully inkjet printing process possesses the advantages of direct patterning and low-cost. It does not require photolithography and etching processes since the pattern is directly printed on the flexible sheet. The center frequency of this prototype is matched with the design frequency. The prototype demonstrates that the presented flexible SAW device is available for the possible application in future. It may be applied to the sensing on curve surface.

  16. Dose dispenser for radioactive gas

    An activity metering apparatus for metering predetermined activities of radioactive gas from a supply ampul to dose vials is described. The apparatus includes a shielded ampul housing, a fine metering valve communicating with the ampul housing chamber, a shielded vial housing and a hypodermic needle communicating with the metering valve and received through an opening in the vial housing. A Geiger-Muller tube is adjustably supported opposite an opening in the vial housing, whereby the activity of the radioactive gas dispensed to a partially evacuated vial within the vial chamber may be read directly by a standard laboratory rate meter

  17. Prescription habits of dispensing and non-dispensing doctors in Zimbabwe

    Trap, Birna; Hansen, Ebba Holme; Hogerzeil, Hans V

    2002-01-01

    The number of dispensing doctors has increased in the last decade, but the implication of this trend on the quality of health care and drug use is unknown. We present a comparative drug utilization study of 29 dispensing doctors and 28 non-dispensing doctors in Zimbabwe based on standard indicato...

  18. Atlantic Herring Acoustic Surveys

    National Oceanic and Atmospheric Administration, Department of Commerce — The NEFSC Advanced Sampling Technologies Research Group conducts annual fisheries acoustic surveys using state-of-the-art acoustic, midwater trawling, and...

  19. Remote erosion and corrosion monitoring of subsea pipelines using acoustic telemetry and wet-mate connector technology

    Painter, Howard; Barlow, Stewart [Teledyne ODI, Thousand Oaks, CA (United States); Clarke, Daniel [Teledyne Cormon, Thousand Oaks, CA (United States); Green, Dale [Teledyne Benthos, North Falmouth, MA (United States)

    2009-07-01

    This paper will present a novel approach for monitoring erosion and corrosion using proven sub sea technologies: intrusive erosion and corrosion monitoring, acoustic telemetry and wet-mateable connector technology. Intrusive metal loss based monitoring systems on sub sea pipelines are increasingly being used because of their ability to directly measure erosion and corrosion. These systems are integrated with the sub sea production control system or located close to the platform and hard-wired. However, locations remote from a sub sea control system or platform requires a dedicated communication system and long lengths of cable that can be cost prohibitive to procure and install. The system presented consists of an intrusive erosion or corrosion monitor with pressure and temperature transmitters, a retrievable electronics module with an acoustic modem, a data storage module, and a replaceable power module. Time-stamped erosion and corrosion data can be transmitted via an acoustic link to a surface platform, a vessel of opportunity or to a relaying modem. Acoustic signals can be transmitted up to 6 km from the monitoring location. The power module along with data module and acoustic modem are mounted on the erosion and corrosion module using wet-mateable connectors, allowing retrieval by remotely operated vehicles. The collected data can be used to assess the cumulative erosion and corrosion as well as use the real-time metal loss rate data to correlate with operational parameters. Benefits include optimization of corrosion inhibitor dosage rates, mitigation of damage caused by solids production, and increased flow assurance. (author)

  20. Final developments, validation and technology transfer for AE (acoustic emission) and SAFT-UT (Synthetic Aperture Focusing of Ultrasonic Testing)

    The program for validation and technology transfer for acoustic emission (AE) and Synthetic Aperture Focusing of Ultrasonic Testing (SAFT-UT) is designed to accomplish the final step of moving research results into beneficial application. Accomplishments for FY88 in the areas of AE and SAFT-UT data under this program are discussed in this paper. the information is treated under the topics of code activities, field validation, and seminars. Projected FY89 activities will continue to focus on these three areas

  1. 改良配药技术对减少输液微粒污染提高输液安全性的研究%Research on improved dispensing technology to reduce infusion particle pollution and raise infusion security

    许美芳; 杨会容; 柏艳; 茹瑞芝; 梁丽珠

    2011-01-01

    目的 探讨安全配药的最优方法,提高配药工作效率.方法 实验组和对照组各30例,对照组按常规方法 配药,实验组采用改良方法 配药,观察两组配药后产生不溶性微粒的数量.结果 实验组产生≥10 μm(个/ml)和≥25μm(个/ml)的数量明显低于对照组(P<0.01),但两组均未达到中国药典标准.结论 改良法配药能减少输液微粒污染,但建立静脉输液配药中心或安装超净工作台配药是非常必要的.%Objective To investigate the optimal method of dispensing safety, and increase work efficacy. Methods The experimental group and control group were collected with 30 cases respectively. The control group was treated with conventional dispensing methods, experimental group improved dispensing method. The number of insoluble particles was observed between the two groups. Results The experimental group showed ≥ 10 microns (a/ml), and ≥ 25 microns (a/ml) than in the control group (P < 0. 01), but both failed to meet the standards of the Chinese Pharmacopoeia. Conclusions The modified method can reduce the transfusion of dispensing particulate pollution, but the establishment of intravenous infusion center or install clean benches pharmacy dispensing is necessary.

  2. Acoustical Imaging

    Akiyama, Iwaki

    2009-01-01

    The 29th International Symposium on Acoustical Imaging was held in Shonan Village, Kanagawa, Japan, April 15-18, 2007. This interdisciplinary Symposium has been taking place every two years since 1968 and forms a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. In the course of the years the volumes in the Acoustical Imaging Series have developed and become well-known and appreciated reference works. Offering both a broad perspective on the state-of-the-art in the field as well as an in-depth look at its leading edge research, this Volume 29 in the Series contains again an excellent collection of seventy papers presented in nine major categories: Strain Imaging Biological and Medical Applications Acoustic Microscopy Non-Destructive Evaluation and Industrial Applications Components and Systems Geophysics and Underwater Imaging Physics and Mathematics Medical Image Analysis FDTD method and Other Numerical Simulations Audience Researcher...

  3. Laboratory {open_quotes}proof of principle{close_quotes} investigation for the acoustically enhanced remediation technology

    Iovenitti, J.L.; Spencer, J.W. Jr.; Hill, D.G. [Weiss Associates, Emergyville, CA (United States)] [and others

    1995-10-01

    Weiss Associates is conducting a three phase program investigating the systematics of using acoustic excitation fields (AEFs) to enhance the in-situ remediation of contaminated soil and ground water under both saturated and unsaturated conditions: Phase I - Laboratory Scale Parametric Investigation; Phase II - Technology Scaling Study; and Phase III - Large Scale Field Tests. Phase I, the subject of this paper, consisted primarily of a laboratory proof of principle investigation. The field deployment and engineering viability of acoustically enhanced remediation (AER) technology was also examined. Phase II is a technology scaling study addressing the scale up between laboratory size samples on the order of inches, and the data required for field scale testing, on the order of hundreds of feet. Phase III will consist of field scale testing at an non-industrialized, non-contaminated site and at a contaminated site to validate the technology. Summarized herein are the results of the Phase I {open_quotes}proof-of-principle{close_quotes} investigation, and recommendations for Phase H. A general overview of AER technology along with the plan for the Phase I investigation was presented.

  4. All dispenser printed flexible 3D structured thermoelectric generators

    Cao, Z.; Shi, J. J.; Torah, R. N.; Tudor, M. J.; Beeby, S. P.

    2015-12-01

    This work presents a vertically fabricated 3D thermoelectric generator (TEG) by dispenser printing on flexible polyimide substrate. This direct-write technology only involves printing of electrodes, thermoelectric active materials and structure material, which needs no masks to transfer the patterns onto the substrate. The dimension for single thermoelectric element is 2 mm × 2 mm × 0.5 mm while the distance between adjacent cubes is 1.2 mm. The polymer structure layer was used to support the electrodes which are printed to connect the top ends of the thermoelectric material and ensure the flexibility as well. The advantages and the limitations of the dispenser printed 3D TEGs will also be evaluated in this paper. The proposed method is potential to be a low-cost and scalable fabrication solution for TEGs.

  5. Dispensing Equipment Testing with Mid-Level Ethanol/Gasoline Test Fluid: Summary Report

    Boyce, K.; Chapin, J. T.

    2010-11-01

    The National Renewable Energy Laboratory's (NREL) Nonpetroleum-Based Fuel Task addresses the hurdles to commercialization of biomass-derived fuels and fuel blends. One such hurdle is the unknown compatibility of new fuels with current infrastructure, such as the equipment used at service stations to dispense fuel into automobiles. The U.S. Department of Energy's (DOE) Vehicle Technology Program and the Biomass Program have engaged in a joint project to evaluate the potential for blending ethanol into gasoline at levels higher than nominal 10 volume percent. This project was established to help DOE and NREL better understand any potentially adverse impacts caused by a lack of knowledge about the compatibility of the dispensing equipment with ethanol blends higher than what the equipment was designed to dispense. This report provides data about the impact of introducing a gasoline with a higher volumetric ethanol content into service station dispensing equipment from a safety and a performance perspective.

  6. Structure optimization of the dispensing house in a combustion train for a thermal bake-out aluminum reduction cell

    WU Chengbo; CHANG Baolong; ZHANG Li; ZHANG Binghuai

    2003-01-01

    The fume bake-out aluminum reduction cell is a novel technology possessing such advantages as easy control for the speed of heating-up, well-distributed temperature, and little cathode and anode oxidation. The key equipment of fume bake-out is a combustion train whose one important part is a dispensing house. This work deals with the numerical model and the flow and temperature fields of the dispensing house, which suggests that uniformity of flow and energy distribution is influenced by the position, shape and direction of the nozzle and cross dimension of dispensing house mainly, but is less influenced by entry speed The parameters of the dispensing house structure are optimised to satisfy the requirements for a combustion train in fume bakeout, and appropriate dimensions are obtained for a dispensing house structure.

  7. Assessment of the application of acoustic emission technology for monitoring the presence of sand under multiphase flow condition

    The monitoring of multiphase flow is an established process that has spanned several decades. This paper demonstrates the use of acoustic emission (AE) technology to investigate sand transport characteristic in three-phase (air-water-sand) flow in a horizontal pipe where the superficial gas velocity (VSG) had a range of between 0.2 ms−1 to 2.0 ms−1 and superficial liquid velocity (VSL) had a range of between 0.2 ms−1 to 1.0 ms−1. The experimental findings clearly show a correlation exists between AE energy levels, sand concentration, superficial gas velocity (VSG) and superficial liquid velocity (VSL)

  8. Using of acoustic technologies for detection of explosives in gas, liquid and solid medium

    Full text: Some industrial nuclear power objects are very attractive for the realization of radiological and chemical terrorism acts with using of explosives. Although up today this type of terrorism is not revealed itself, but the problem of detection of explosives at these objects is becoming very actual one, for example, in connection with the implementation of the urgent decommissioning of nuclear powered vessels. Such decommissioning includes the utilization the dangerous radioactive and chemical elements, contained in submarines and vessels. This actual problem is existed not only in Russia, but also in abroad. It is noticed that catastrophes at these objects will have in addition the great negative mental effect on population of all over the world, as it was after the Chernobyl accident. The using of the modern nuclear physics methods for detection and analysis of explosives is connected with the following difficulties: (1) we have to have the unique and the expensive equipment; (2) the special preparation of sample probes; (3) a long time is often necessary for analysis; (4) the high qualification of service personal is needed. We proposed to use for these purposes the complex of acoustic techniques, that are based on the high sensitivity of acoustic characteristics of any matter to their physical and chemical properties.Any acoustic signal has the following main parameters: (1) frequency (ω); (2) amplitude of pressure (ρ); (3) wave and amplitude bands; (4) velocity of acoustic wave propagation (sound velocity) (C); (5) space and temporal signal evolution, that is determined by the values of coefficients of temporal attenuation (α), space adsorption (β) and sound dispersion on obstacles and impurities. Our acoustic analysis is included the determination of C, α and β values for solid and liquid explosives. The exact measurements of these parameters and their dependences from frequency and temperature are conducted in the special acoustic cells, that

  9. A pipette dispenses a charged droplet

    Choi, Dongwhi; Lee, Horim; Im, Do Jin; Kang, In Seok; Kang, Kwan Hyoung

    2012-11-01

    Micropipettes are widely used in many scientific and engineering fields. However, it is hardly known that a droplet dispensed from a plastic pipette tip has a considerable amount of charges (order of 10-10 C). Here we report that the charged droplet is dispensed from a commercial and disposable plastic pipette tip and this charge is originated from the natural electrification between a solution and the inner surface of the pipette tip. The charge amount is dependent on not only the physicochemical properties of a solution (e.g., pH and a concentration) but also dispensing environments (e.g., atmospheric humidity and type of commercial pipette tip). To investigate the effects of the charge on the droplet dispensing, we calculate the electrical force between the droplet and the pipette tip though numerical simulation. The micropipette users especially, who are dealing with discrete droplets in their experiments, should consider this charge effect in their dispensing of a droplet. This work was supported by the National Research Foundation of Korea (NRF) Grant No. R0A-2007-000-20098-0 funded by the Korea government (MEST) and No. 20090083510 through Multiphenomena CFD Engineering Research Center.

  10. Visualization of Surface Acoustic Waves in Thin Liquid Films

    Rambach, R. W.; Taiber, J.; C. M. L. Scheck; Meyer, C.; Reboud, J.; Cooper, J M; Franke, T.

    2016-01-01

    We demonstrate that the propagation path of a surface acoustic wave (SAW), excited with anWe demonstrate that the propagation path of a surface acoustic wave (SAW), excited with an interdigitated transducer (IDT), can be visualized using a thin liquid film dispensed onto a lithium niobate (LiNbO3) substrate. The practical advantages of this visualization method are its rapid and simple implementation, with many potential applications including in characterising acoustic pumping within microfl...

  11. Research on Dispensing Mechanism of Active Code in Active Network

    WANG Jian-guo; LI Zeng-zhi; KOU Ya-nan

    2003-01-01

    The dispensing mechanism of active code is the key technology in active network. Conventional capsule and programmable switch approaches have their own shortcomings. DCCAN mechanism presented in this paper overcomes their shortcomings. In this paper, capsule and programmable switch approaches are introduced and their shortcomings are analyzed. The principle of DCCAN mechanism is described. The theoretical analyses in transmission bandwidth based on DCCAN mechanism and capsule approach are described, and key factors which affect the transmission bandwidth based on DCCAN mechanism are also discussed. At the same time, the theoretical analyses in latency based on DCCAN mechanism and capsule approach are described. The using condition of DCCAN mechanism is also discussed.

  12. Hydrodynamic, Heat and Acoustic Processes Modelling in Tranport of Rheologically Complex Viscous Media Technology in Pipelines

    The paper describes the results of mathematical modelling of acoustic processes, hydrodynamics and heat exchange in case of oil products transportation in pipelines with constant and variable cross-section. The turbulence model features of RANS approach and intensification of heat exchange in substances with anomalous rheology are reviewed. It is shown that statistic second order models are appropriate to use for forecasting details of the pulsating flows. The paper states the numerical integration features of determining equations. The properties of vibratory effect influence are determined. Vortex and heat perturbations, rheological changes impact on resistance regularities and intensity of heat exchange are analyzed

  13. Process For Patterning Dispenser-Cathode Surfaces

    Garner, Charles E.; Deininger, William D.

    1989-01-01

    Several microfabrication techniques combined into process cutting slots 100 micrometer long and 1 to 5 micrometer wide into tungsten dispenser cathodes for traveling-wave tubes. Patterned photoresist serves as mask for etching underlying aluminum. Chemically-assisted ion-beam etching with chlorine removes exposed parts of aluminum layer. Etching with fluorine or chlorine trifluoride removes tungsten not masked by aluminum layer. Slots enable more-uniform low-work function coating dispensed to electron-emitting surface. Emission of electrons therefore becomes more uniform over cathode surface.

  14. 30 CFR 75.1905 - Dispensing of diesel fuel.

    2010-07-01

    ... from other than safety cans must be dispensed by means of— (1) Gravity feed with a hose equipped with a...) An anti-siphoning device. (c) Diesel fuel must not be dispensed using compressed gas. (d) Diesel...

  15. Assessment of the application of acoustic emission technology for monitoring the presence of sand under multiphase flow condition

    El-Alej, M., E-mail: m.elalej@cranfield.ac.uk; Mba, D., E-mail: m.elalej@cranfield.ac.uk; Yeung, H., E-mail: m.elalej@cranfield.ac.uk [School of Engineering, Cranfield University, Cranfield, Bedfordshire, MK43 OAL (United Kingdom)

    2014-04-11

    The monitoring of multiphase flow is an established process that has spanned several decades. This paper demonstrates the use of acoustic emission (AE) technology to investigate sand transport characteristic in three-phase (air-water-sand) flow in a horizontal pipe where the superficial gas velocity (VSG) had a range of between 0.2 ms{sup −1} to 2.0 ms{sup −1} and superficial liquid velocity (VSL) had a range of between 0.2 ms{sup −1} to 1.0 ms{sup −1}. The experimental findings clearly show a correlation exists between AE energy levels, sand concentration, superficial gas velocity (VSG) and superficial liquid velocity (VSL)

  16. Foam-Mixing-And-Dispensing Machine

    Chong, Keith Y.; Toombs, Gordon R.; Jackson, Richard J.

    1996-01-01

    Time-and-money-saving machine produces consistent, homogeneously mixed foam, enhancing production efficiency. Automatically mixes and dispenses polyurethane foam in quantities specified by weight. Consists of cart-mounted, air-driven proportioning unit; air-activated mechanical mixing gun; programmable timer/counter, and controller.

  17. 21 CFR 872.3080 - Mercury and alloy dispenser.

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Mercury and alloy dispenser. 872.3080 Section 872...) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3080 Mercury and alloy dispenser. (a) Identification. A mercury and alloy dispenser is a device with a spring-activated valve intended to measure...

  18. Dispensing and bio-functionalization of giant unilamellar vesicles on a chip

    Kaler, K V I S; Prakash, R, E-mail: kaler@ucalgary.ca [2500 University Drive NW, Calgary, AB - T2N 1N4 (Canada)

    2011-06-23

    Giant unilamellar vesicles (GUVs), typically >10 {mu}m in diameter, can serve as interesting models for mimicking biological membranes and furthermore can be usefully leveraged in drug delivery and bio-sensor applications. In this paper, we have demonstrated a chip based vesicle dispensing scheme that utilizes liquid dielectrophoresis (L-DEP) to dispense, precisely positioned GUVs over a range of diameter 30 - 100 {mu}m, a capability that is not readily achieved by either conventional or microchannel technology. These GUVs can also be individually addressed and tailored for a variety of applications such as bio-sensing and cell-on-a-chip.

  19. High-resolution shallow seismic surveying using parametric acoustic source technology

    Vestrheim, M.; Lunde, P. (Chr.Michelsen Institute, Dept. of science and Technology, Bergen (Norway)); Meldahl, P.; Statoil (Geology and Geophysics Dept., Stavanger (Norway))

    1988-01-01

    The paper briefly discusses the potentials of using parametric source technology for improving shallow gas surveying operations. The use of a parametric source offers several important advantageous features, such as a broad frequency bandwidth, flexibility in pulse shaping, improved stability and repeatability, and high directivity. Through optimization of performance the application of parametric source technology for shallow gas surveying is seen to be technologically feasible. 6 figs., 3 refs. (Author).

  20. Fabrication and measurement of regenerable low work function dispenser photocathodes

    Moody, Nathan A.

    Laser-switched photoemitters are a source of electrons for high current applications such as free electron lasers. Laser-modulated photoemission permits rapid switching of the electron beam, far surpassing what can be achieved using electric-field gated emission. Photoinjector systems consist of a drive laser producing short bunches of photons and an efficient photocathode, which converts photon bunches into electron beam pulses. Development of both technologies is required, but the scope of this project is restricted to improvement of the photocathode. Most high-efficiency photocathodes employ cesium-based surface coatings to reduce work function and enable efficient electron emission in the visible range. Lifetime is severely limited by the loss of this delicate coating, which degrades rapidly in practical vacuum environments. More robust photocathodes exist, but have much lower efficiency, and place unrealistic demands on drive laser power and stability. This research proposes a novel dispenser concept that dramatically extends the lifetime of high efficiency cesium-based cathodes by continuously or periodically restoring the cesium surface monolayer during an in situ rejuvenation process. Sintered tungsten provides an interface between a cesium reservoir and the photoemitting surface. During temperature-controlled rejuvenation, cesium diffuses through and across the sintered tungsten to create and sustain a low-work function photocathode. The prototype dispenser cathode was fabricated and tested for two modes of operation: continuous and periodic near-room temperature rejuvenation. The data are compared with a photoemission model of partially covered surfaces under design for integration with existing beam simulations. Overall performance suggests that this cesium-delivery mechanism can significantly enhance the efficiency and operational lifetime of a wide variety of present and future cesium-based photocathodes. Also reported are surface characterization, ion

  1. Acoustic vector sensor signal processing

    SUN Guiqing; LI Qihu; ZHANG Bin

    2006-01-01

    Acoustic vector sensor simultaneously, colocately and directly measures orthogonal components of particle velocity as well as pressure at single point in acoustic field so that is possible to improve performance of traditional underwater acoustic measurement devices or detection systems and extends new ideas for solving practical underwater acoustic engineering problems. Although acoustic vector sensor history of appearing in underwater acoustic area is no long, but with huge and potential military demands, acoustic vector sensor has strong development trend in last decade, it is evolving into a one of important underwater acoustic technology. Under this background, we try to review recent progress in study on acoustic vector sensor signal processing, such as signal detection, DOA estimation, beamforming, and so on.

  2. Infrared photoelectron emission from Scandate dispenser cathodes

    Jensen, Kevin L.; Feldman, Donald W.; Virgo, Matt; O'Shea, Patrick G.

    2003-08-01

    Nonlinear photoelectric emission from Scandate dispenser cathodes using 1.064-μm radiation in nanosecond-scale pulses has been observed. Unlike single-photon emission, the photocurrent is a strong function of both the initial lattice temperature and the applied electric field as well as laser intensity. The parametric data is compared to a theoretical model for the process, and the data is shown to be explicable in terms of laser heating of the electron gas and subsequent photoemission.

  3. Development of automated blender and dispensing system

    This paper describes automated blender and dispensing system designed and developed in Nuclear Recycle Board for its reprocessing plant. Obtaining sinterable grade oxide powder from the product solution received in the heavy metal product line involves skilled manpower and time consuming, laborious manual operations. Entire treatment is carried out in a train of closed containments called as glove boxes. In view of this Automated blender and dispensing system has been developed to reduce tedious manual operations. System consists of PLC based control system to drive motorised charging mechanism, a conical ribbon blender which homogenises the product and load cell triggered, indexing dispensing mechanism. Schematic design of the system has been done in-house, while fabrication was outsourced. System has been built, tested and installed at component test facility (CTF) at Tarapur. Actual blending tests were carried out by using dummy material like calcium carbonate and barium carbonate powder, with different sets of parameter. Blended product was chemically analysed for its homogeneity. System has now been put to trial runs by operating staff. This development has circumvented tedious operations of Scooping and increased the throughput. This paper describes challenges in undertaking this developmental work. (author)

  4. [Economic analysis of strategic behavior in dispensing pharmacies in the separation of dispensing and prescribing functions].

    Sakurai, Hidehiko

    2003-03-01

    In recent years, the system for the separation of dispensing and prescribing functions (SDP) has progressed in Japan. However, because of the failure of the healthcare system, it is difficult to estimate how the system of SDP contributes to the improvement of patient utility and welfare. In this paper, I try to evaluate the SDP by analyzing the strategic behavior of dispensing pharmacies, employing some economic models under imperfect information. In these models, quality is characterized as a strategic variable in monopolistic or duopolistic competition. As a result, I show that competition among dispensing pharmacies in the SDP raises the quality of pharmaceutical services, but there is some possibility of "excess entry" with free entry. PMID:12693020

  5. Acoustically enhanced heat transport

    Ang, Kar M.; Hung, Yew Mun; Tan, Ming K., E-mail: tan.ming.kwang@monash.edu [School of Engineering, Monash University Malaysia, 47500 Bandar Sunway, Selangor (Malaysia); Yeo, Leslie Y. [Micro/Nanophysics Research Laboratory, RMIT University, Melbourne, VIC 3001 (Australia); Friend, James R. [Department of Mechanical and Aerospace Engineering, University of California, San Diego, California 92093 (United States)

    2016-01-15

    We investigate the enhancement of heat transfer in the nucleate boiling regime by inducing high frequency acoustic waves (f ∼ 10{sup 6} Hz) on the heated surface. In the experiments, liquid droplets (deionized water) are dispensed directly onto a heated, vibrating substrate. At lower vibration amplitudes (ξ{sub s} ∼ 10{sup −9} m), the improved heat transfer is mainly due to the detachment of vapor bubbles from the heated surface and the induced thermal mixing. Upon increasing the vibration amplitude (ξ{sub s} ∼ 10{sup −8} m), the heat transfer becomes more substantial due to the rapid bursting of vapor bubbles happening at the liquid-air interface as a consequence of capillary waves travelling in the thin liquid film between the vapor bubble and the air. Further increases then lead to rapid atomization that continues to enhance the heat transfer. An acoustic wave displacement amplitude on the order of 10{sup −8} m with 10{sup 6} Hz order frequencies is observed to produce an improvement of up to 50% reduction in the surface temperature over the case without acoustic excitation.

  6. How often are spectacle lenses not dispensed as prescribed?

    Kanwar Mohan

    2012-01-01

    Full Text Available Spectacles are routinely prescribed by the ophthalmologist and dispensed by the opticians. We investigated how frequently the spectacles are not dispensed as prescribed and whether the frequency of inaccurate spectacles would decrease if the patients, at the time of collecting spectacles, ask the optician to verify that the spectacles have been dispensed accurately. We found inaccurate spectacles in about one-third of our patients and incorrect spherocylinders more frequently with an error in the spherical element and cylinder axis. These inaccuracies decreased significantly when patients while collecting spectacles, asked the optician to verify the accuracy of the spectacles dispensed. It is suggested that while prescribing spectacles, the patients should be made aware of the possibility of dispensing errors. To decrease the frequency of incorrect spectacles, the patients while collecting spectacles, should ask the optician to check whether the spectacles have been dispensed accurately.

  7. Disease Propagation Analysis and Mitigation Strategies for Effective Mass Dispensing*

    Lee, Eva K.; Chen, Chien H; Pietz, Ferninand; Benecke, Bernard

    2010-01-01

    Mass dispensing of medical countermeasures has been proven to be an effective and crucial means to contain the outbreak of highly infectious disease. The large influx of individuals to the point-of dispensing (POD) centers to receive vaccinations or prophylactic treatment, however, raises the potential risk of serious intra-facility cross-infections. To mitigate the effect, a thorough understanding of how disease propagates during the dispensing under different transmission parameters versus ...

  8. Drug dispensing errors in a ward stock system

    Andersen, Stig Ejdrup

    2010-01-01

    . Multivariable analysis showed that surgical and psychiatric settings were more susceptible to involvement in dispensing errors and that polypharmacy was a risk factor. In this ward stock system, dispensing errors are relatively common, they depend on speciality and are associated with polypharmacy. These...... results indicate that strategies to reduce dispensing errors should address polypharmacy and focus on high-risk units. This should, however, be substantiated by a future trial....

  9. Direct-Dispense Polymeric Waveguides Platform for Optical Chemical Sensors

    Mohamad Hajj-Hassan; Timothy Gonzalez; Ebrahim Ghafar-Zadeh; Hagop Djeghelian; Vamsy Chodavarapu; Daniel Therriault; Mark Andrews

    2008-01-01

    We describe an automated robotic technique called direct-dispense to fabricate a polymeric platform that supports optical sensor arrays. Direct-dispense, which is a type of the emerging direct-write microfabrication techniques, uses fugitive organic inks in combination with cross-linkable polymers to create microfluidic channels and other microstructures. Specifically, we describe an application of direct-dispensing to develop optical biochemical sensors by fabricating planar ridge waveguides...

  10. Prescription, dispensation and marketing patterns of methylphenidate

    Edson Perini

    2014-12-01

    Full Text Available OBJECTIVE To analyze the patterns and legal requirements of methylphenidate consumption. METHODS We conducted a cross-sectional study of the data from prescription notification forms and balance lists of drugs sales – psychoactive and others – subject to special control in the fifth largest city of Brazil, in 2006. We determined the defined and prescribed daily doses, the average prescription and dispensation periods, and the regional sales distribution in the municipality. In addition, we estimated the costs of drug acquisition and analyzed the individual drug consumption profile using the Lorenz curve. RESULTS The balance lists data covered all notified sales of the drug while data from prescription notification forms covered 50.6% of the pharmacies that sold it, including those with the highest sales volumes. Total methylphenidate consumption was 0.37 DDD/1,000 inhabitants/day. Sales were concentrated in more developed areas, and regular-release tablets were the most commonly prescribed pharmaceutical formulation. In some regions of the city, approximately 20.0% of the prescriptions and dispensation exceeded 30 mg/day and 30 days of treatment. CONCLUSIONS Methylphenidate was widely consumed in the municipality and mainly in the most developed areas. Of note, the consumption of formulations with the higher abuse risk was the most predominant. Both its prescription and dispensation contrasted with current pharmacotherapeutic recommendations and legal requirements. Therefore, the commercialization of methylphenidate should be monitored more closely, and its use in the treatment of behavioral changes of psychological disorders needs to be discussed in detail, in line with the concepts of the quality use of medicines.

  11. Wafer level fabrication of single cell dispenser chips with integrated electrodes for particle detection

    This work presents the microfabrication and experimental evaluation of a dispenser chip, designed for isolation and printing of single cells by combining impedance sensing and drop-on-demand dispensing. The dispenser chip features 50  ×  55 µm (width × height) microchannels, a droplet generator and microelectrodes for impedance measurements. The chip is fabricated by sandwiching a dry film photopolymer (TMMF) between a silicon and a Pyrex wafer. TMMF has been used to define microfluidic channels, to serve as low temperature (75 °C) bonding adhesive and as etch mask during 300 µm deep HF etching of the Pyrex wafer. Due to the novel fabrication technology involving the dry film resist, it became possible to fabricate facing electrodes at the top and bottom of the channel and to apply electrical impedance sensing for particle detection with improved performance. The presented microchip is capable of dispensing liquid and detecting microparticles via impedance measurement. Single polystyrene particles of 10 µm size could be detected with a mean signal amplitude of 0.39  ±  0.13 V (n=439) at particle velocities of up to 9.6 mm s−1 inside the chip. (paper)

  12. Improving Pharmacy Dispensing Performance Through Time Management

    Shaat, Mohamed

    2011-01-01

    The aim of this project was to carry out a change model in one of Family Medicine Clinic’s Pharmacy in Abu Dhabi. While, the objectives of the project were to improve patient satisfaction through improving patient waiting time for medications collection, improving patient’s knowledge about the pharmacy services and then generalize the implemented change in all other six clinic’s pharmacies. The change was happened because of current system of dispensing patient’s prescription ‘in turn’, which...

  13. Oxidation studies of impregnated dispenser cathodes

    We report on surface studies of the type M and type S impregnated dispenser cathode using synchrotron radiation photoemission spectroscopy. The results indicate the presence of two barium configurations on the room temperature type S surface, probably barium metal and BaO. The room-temperature type M cathode has about a monolayer of barium metal and about a monolayer of tungsten, apparently alloyed to the Os/Ru coating, on the surface. The barium-related features of the type S cathode are extremely sensitive to small oxygen exposures, while the tungsten-related features are more sensitive to oxygen in the type M cathode

  14. A model of dispenser cathode activity

    Lamartine, B. C.; Eyink, K. G.; Czarnecki, J. V.; Lampert, W. V.; Haas, T. W.

    1985-12-01

    A semiquantitative model of dispenser cathode activity based on recent work on the co-adsorption of Ba and O onto W surfaces is presented. The co-adsorption studies have determined the shape of a three-dimensional surface of work function as a function of θO and θBa, the surface coverages of O and Ba, respectively. Compositions of a variety of pedigreed dispenser cathodes were fitted to this surface and their composition changes during lifetime were modeled. Changes of surface composition with temperature and of workfunction, φ, with temperature were also found to fit these curves. The concept of a patchy surface implied by the co-adsorption measurements was used to explain earlier results on the shape of the X-ray excited Ba MNN Auger feature. Finally, SIMS measurements under UHV conditions was found to provide an extremely sensitive measurement of surface composition in the region of surface coverages of interest in the study of cathode phenomena. Extensions of this work to other types of cathodes such as M-types, and rhenium substrate cathodes is also discussed.

  15. 14 CFR 137.39 - Economic poison dispensing.

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Economic poison dispensing. 137.39 Section... AIRCRAFT OPERATIONS Operating Rules § 137.39 Economic poison dispensing. (a) Except as provided in... economic poison that is registered with the U.S. Department of Agriculture under the Federal...

  16. Acoustic Neuroma

    An acoustic neuroma is a benign tumor that develops on the nerve that connects the ear to the brain. The tumor ... press against the brain, becoming life-threatening. Acoustic neuroma can be difficult to diagnose, because the symptoms ...

  17. Acoustic Neuroma

    An acoustic neuroma is a benign tumor that develops on the nerve that connects the ear to the brain. ... can press against the brain, becoming life-threatening. Acoustic neuroma can be difficult to diagnose, because the ...

  18. Acoustic hemostasis

    Crum, L.; Andrew, M.; Bailey, M.; Beach, K.; Brayman, A.; Curra, F.; Kaczkowski, P.; Kargl, S.; Martin, R.; Vaezy, S.

    2003-04-01

    Over the past several years, the Center for Industrial and Medical Ultrasound (CIMU) at the Applied Physics Laboratory in the University of Washington has undertaken a broad research program in the general area of High Intensity Focused Ultrasound (HIFU). Our principal emphasis has been on the use of HIFU to induce hemostasis; in particular, CIMU has sought to develop a small, lightweight, portable device that would use ultrasound for both imaging and therapy. Such a technology is needed because nearly 50% of combat casualty mortality results from exsanguinations, or uncontrolled bleeding. A similar percentage occurs for civilian death due to trauma. In this general review, a presentation of the general problem will be given, as well as our recent approaches to the development of an image-guided, transcutaneous, acoustic hemostasis device. [Work supported in part by the USAMRMC, ONR and the NIH.

  19. Short pulse photoemission from a dispenser cathode

    Bergeret, H.; Boussoukaya, M.; Chehab, R.; Leblond, B.; Le Duff, J.

    1991-03-01

    Pulsed photoemission in the picosecond regime has been obtained from a standard thermionic dispenser cathode (WBaCa) at temperatures below the measurable thermoemission threshold. A picosecond Nd : YAG mode locked laser has been used at both green and UV light. Micropulse charges up to 0.5 nC have been measured on a wideband coaxial pickup located behind the anode. They correspond to an electron saturation limit from an approximately 20 mm 2 illuminated cathode area with a surface field of 3 MV/m. The effective cathode efficiency at small laser energies, defined as the number of electrons impinging on the coaxial pickup divided by the number of photons impinging on the cathode, is about 2 × 10 -5.

  20. Short pulse photoemission from a dispenser cathode

    Pulsed photoemission in picosecond regime has been obtained from a standard thermionic dispenser cathode (W - Ba - Ca) at temperatures below measurable thermoemission threshold. A picosecond Nd: YAG mode locked laser has been used at both green and U.V. light. Micro-pulse charges up to 0.5 nC have been measured on a wideband coaxial pick up located behind the anode. They correspond to an electron saturation limit from an approximately 20 mm2 illuminated cathode area with a surface field of 3 MV/m. The effective cathode efficiency at small laser energies, defined as the number of electron impinging the coaxial pick up divided by the number of photons impinging the cathode, is about 2.10-5

  1. Physics of thermionic dispenser cathode aging

    Longo, R. T.

    2003-11-01

    A dispenser cathode life model (DCLM) was originally published in 1984. More recent life test data have substantiated the basic physics used in the DCLM. However, re-evaluation of the model with this latest data alters the numerical parameters used in the model. The most important modification is the incorporation of the shape factor, α, in the emission equation, so that accurate descriptions of the cathode activity curves (i.e., current versus temperature) can be made as a function of cathode age. The original model was fit only to the cathode current as a function of time for a fixed operating temperature. This revision fits the cathode activity curves as a function of both time and cathode temperature. Variation in cathode current as a function of temperature is quite dependent upon the underlying physics, and gives a better measure of how the internal parameters, such as work function and knee position and knee shape change with time. Knowing these details provides a more accurate measure of how the cathode current at the operating point will change over time. The modification made to the emission equation in this revision incorporates the shape factor, α, which is a single number that describes the shape of the cathode activity curves. The shape factor is found to be dependent on time: The knee softens and rounds with age. Even though the shape factor was originally introduced as an empirical factor, I will present a theoretical model for the shape factor that provides some insight into its physical interpretation. This theory will show that it can be related to the thermodynamics of the emitter surface. The re-evaluation of the DCLM, based on the latest life data, and including the theory for the shape factor yields a longer life expectancy for the M-type dispenser cathode then was predicted by the original more conservative life model. The DCLM matches the observed life data more accurately.

  2. Bathymetric surveys of Morse and Geist Reservoirs in central Indiana made with acoustic Doppler current profiler and global positioning system technology, 1996

    Wilson, J.T.; Morlock, S.E.; Baker, N.T.

    1997-01-01

    Acoustic Doppler current profiler, global positioning system, and geographic information system technology were used to map the bathymetry of Morse and Geist Reservoirs, two artificial lakes used for public water supply in central Indiana. The project was a pilot study to evaluate the use of the technologies for bathymetric surveys. Bathymetric surveys were last conducted in 1978 on Morse Reservoir and in 1980 on Geist Reservoir; those surveys were done with conventional methods using networks of fathometer transects. The 1996 bathymetric surveys produced updated estimates of reservoir volumes that will serve as base-line data for future estimates of storage capacity and sedimentation rates.An acoustic Doppler current profiler and global positioning system receiver were used to collect water-depth and position data from April 1996 through October 1996. All water-depth and position data were imported to a geographic information system to create a data base. The geographic information system then was used to generate water-depth contour maps and to compute the volumes for each reservoir.The computed volume of Morse Reservoir was 22,820 acre-feet (7.44 billion gallons), with a surface area of 1,484 acres. The computed volume of Geist Reservoir was 19,280 acre-feet (6.29 billion gallons), with a surface area of 1,848 acres. The computed 1996 reservoir volumes are less than the design volumes and indicate that sedimentation has occurred in both reservoirs. Cross sections were constructed from the computer-generated surfaces for 1996 and compared to the fathometer profiles from the 1978 and 1980 surveys; analysis of these cross sections also indicates that some sedimentation has occurred in both reservoirs.The acoustic Doppler current profiler, global positioning system, and geographic information system technologies described in this report produced bathymetric maps and volume estimates more efficiently and with comparable or greater resolution than conventional

  3. Application of acoustic leak detection technology for the detection and location of leaks in light water reactors

    This report presents the results of a study to evaluate the adequacy of leak detection systems in light water reactors. The sources of numerous reported leaks and methods of detection have been documented. Research to advance the state of the art of acoustic leak detection is presented, and procedures for implementation are discussed. 14 refs., 70 figs., 10 tabs

  4. NASA/Army Rotorcraft Technology. Volume 2: Materials and Structures, Propulsion and Drive Systems, Flight Dynamics and Control, and Acoustics

    1988-01-01

    The Conference Proceedings is a compilation of over 30 technical papers presented which report on the advances in rotorcraft technical knowledge resulting from NASA, Army, and industry research programs over the last 5 to 10 years. Topics addressed in this volume include: materials and structures; propulsion and drive systems; flight dynamics and control; and acoustics.

  5. Manufacturing polymeric micro lenses and self-organised micro lens arrays by using microfluidic dispensers

    Micro lenses and micro lens arrays have been widely used in numerous areas. In recent years, direct deposition of micro lenses and micro lens arrays by using drop-on-demand dispensers has been studied. However, the traditional drop-on-demand methods have issues such as expensive facilities and appropriateness for low viscosity materials. In this paper, a novel droplet-based method for fabricating polymeric micro lenses and lens arrays is presented. This method utilises microfluidic devices as dispensers to generate micro- to meso-scale droplets, and uses interfacial forces to control the lens profiles. This new method can create lenses with aperture sizes from 130 μm to 2000 μm for both low and high viscosity materials. It is also capable of fabricating self-organised lens arrays with high fill factors. This technology can simplify the manufacturing process and lower the manufacturing costs of micro lenses and lens arrays. (paper)

  6. Application of basic pharmacology and dispensing practice of antibiotics in accredited drug-dispensing outlets in Tanzania

    Minzi OM

    2013-01-01

    Full Text Available OM Minzi,1 VS Manyilizu21Unit of Pharmacology and Therapeutics, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania, 2Logistics System Strengthening Unit, John Snow Inc, Dar es Salaam, TanzaniaBackground: Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, or duka la dawa baridi (DLDBs, in Tanzania.Methodology: This was a cross-sectional study that was conducted in ADDOs and DLDBs. A simulated client method for data collection was used, and a total of 85 ADDOs, located in Mvomero, Kilombero, and Morogoro rural districts, were compared with 60 DLDBs located in Kibaha district. The research assistants posed as simulated clients and requested to buy antibiotics from ADDOs and DLDBs after presenting a case scenario or disease condition. Among the diseases presented were those requiring antibiotics and those usually managed only by oral rehydration salt or analgesics. The simulated clients wanted to know the antibiotics that were available at the shop. The posed questions set a convincing ground to the dispenser either to dispense the antibiotic directly, request a prescription, or refer the patient to a health facility. Proportions were used to summarize categorical variables between ADDOs and DLDBs, and the chi-square test was used to test for statistical difference between the two drug-outlet types in terms of antibiotic-dispensing practice.Results: As many as 40% of trained ADDO dispensers no longer worked at the ADDO shops, so some of the shops employed untrained staff. A larger proportion of ADDOs than DLDBs dispensed antibiotics without prescriptions (P = 0.004. The overall results indicate that there was no difference between the two types of shops in terms of adhering to regulations for dispensing antibiotics. However, in some circumstances, eg

  7. Principles of musical acoustics

    Hartmann, William M

    2013-01-01

    Principles of Musical Acoustics focuses on the basic principles in the science and technology of music. Musical examples and specific musical instruments demonstrate the principles. The book begins with a study of vibrations and waves, in that order. These topics constitute the basic physical properties of sound, one of two pillars supporting the science of musical acoustics. The second pillar is the human element, the physiological and psychological aspects of acoustical science. The perceptual topics include loudness, pitch, tone color, and localization of sound. With these two pillars in place, it is possible to go in a variety of directions. The book treats in turn, the topics of room acoustics, audio both analog and digital, broadcasting, and speech. It ends with chapters on the traditional musical instruments, organized by family. The mathematical level of this book assumes that the reader is familiar with elementary algebra. Trigonometric functions, logarithms and powers also appear in the book, but co...

  8. Acoustic cloaking and transformation acoustics

    Chen Huanyang [School of Physical Science and Technology, Soochow University, Suzhou, Jiangsu 215006 (China); Chan, C T, E-mail: kenyon@ust.h, E-mail: phchan@ust.h [Department of Physics and the William Mong Institute of NanoScience and Technology, The Hong Kong University of Science and Technology, Clear Water Bay (Hong Kong)

    2010-03-24

    In this review, we give a brief introduction to the application of the new technique of transformation acoustics, which draws on a correspondence between coordinate transformation and material properties. The technique is formulated for both acoustic waves and linear liquid surface waves. Some interesting conceptual devices can be designed for manipulating acoustic waves. For example, we can design acoustic cloaks that make an object invisible to acoustic waves, and the cloak can either encompass or lie outside the object to be concealed. Transformation acoustics, as an analog of transformation optics, can go beyond invisibility cloaking. As an illustration for manipulating linear liquid surface waves, we show that a liquid wave rotator can be designed and fabricated to rotate the wave front. The acoustic transformation media require acoustic materials which are anisotropic and inhomogeneous. Such materials are difficult to find in nature. However, composite materials with embedded sub-wavelength resonators can in principle be made and such 'acoustic metamaterials' can exhibit nearly arbitrary values of effective density and modulus tensors to satisfy the demanding material requirements in transformation acoustics. We introduce resonant sonic materials and Helmholtz resonators as examples of acoustic metamaterials that exhibit resonant behaviour in effective density and effective modulus. (topical review)

  9. Acoustic cloaking and transformation acoustics

    In this review, we give a brief introduction to the application of the new technique of transformation acoustics, which draws on a correspondence between coordinate transformation and material properties. The technique is formulated for both acoustic waves and linear liquid surface waves. Some interesting conceptual devices can be designed for manipulating acoustic waves. For example, we can design acoustic cloaks that make an object invisible to acoustic waves, and the cloak can either encompass or lie outside the object to be concealed. Transformation acoustics, as an analog of transformation optics, can go beyond invisibility cloaking. As an illustration for manipulating linear liquid surface waves, we show that a liquid wave rotator can be designed and fabricated to rotate the wave front. The acoustic transformation media require acoustic materials which are anisotropic and inhomogeneous. Such materials are difficult to find in nature. However, composite materials with embedded sub-wavelength resonators can in principle be made and such 'acoustic metamaterials' can exhibit nearly arbitrary values of effective density and modulus tensors to satisfy the demanding material requirements in transformation acoustics. We introduce resonant sonic materials and Helmholtz resonators as examples of acoustic metamaterials that exhibit resonant behaviour in effective density and effective modulus. (topical review)

  10. Acoustic telemetry.

    Drumheller, Douglas Schaeffer; Kuszmaul, Scott S.

    2003-08-01

    Broadcasting messages through the earth is a daunting task. Indeed, broadcasting a normal telephone conversion through the earth by wireless means is impossible with todays technology. Most of us don't care, but some do. Industries that drill into the earth need wireless communication to broadcast navigation parameters. This allows them to steer their drill bits. They also need information about the natural formation that they are drilling. Measurements of parameters such as pressure, temperature, and gamma radiation levels can tell them if they have found a valuable resource such as a geothermal reservoir or a stratum bearing natural gas. Wireless communication methods are available to the drilling industry. Information is broadcast via either pressure waves in the drilling fluid or electromagnetic waves in the earth and well tubing. Data transmission can only travel one way at rates around a few baud. Given that normal Internet telephone modems operate near 20,000 baud, these data rates are truly very slow. Moreover, communication is often interrupted or permanently blocked by drilling conditions or natural formation properties. Here we describe a tool that communicates with stress waves traveling through the steel drill pipe and production tubing in the well. It's based on an old idea called Acoustic Telemetry. But what we present here is more than an idea. This tool exists, it's drilled several wells, and it works. Currently, it's the first and only acoustic telemetry tool that can withstand the drilling environment. It broadcasts one way over a limited range at much faster rates than existing methods, but we also know how build a system that can communicate both up and down wells of indefinite length.

  11. Comparative Study of Shear Wave Velocities Using Acoustic Radiation Force Impulse Technology in Hepatocellular Carcinoma: The Extent of Radiofrequency Ablation

    Kang, Jiyoung; Kwon, Heejin; Cho, Jinhan; Oh, Jongyoung; Nam, Kyungjin; Yoon, Seongkuk; Kang, Myongjin; Lee, Sungwook; Han, Sangyeong

    2012-01-01

    Background/Aims The purpose of this study was to assess the value of acoustic radiation force impulse (ARFI) for predicting the extent of radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) by correlating the elasticity of HCC and peritumoral parenchyma (as measured by ARFI) with the extent of ablation determined by computed tomography (CT). Methods From September 2009 to June 2011, 158 patients underwent RFA ablation for HCC (single, ≤3 cm). We evaluated the data of a total of 38...

  12. A new dispenser cathode with dual-layer

    Li, Yutao; Zhang, Honglai; Liu, Pukun; Zhang, Mingchen

    2005-09-01

    The emission and surface characteristics of the dispenser cathode coated with Os-W alloy and that coated with Os-W/Re are studied and compared. The dispenser cathode coated with Os-W/Re has been applied in electron gun measurement system for making measurement of higher emission current and life test. We called the cathode coated with Os-W/Re as the cathode with dual-layer. It is found that the dispenser cathode coated with dual-layer has higher current density than that coated only with Os-W alloy. After being activated, the cathode coated with dual-layer presents ternary composition on the surface of it. The W surface composition does not rise with time comparing with that of the cathode coated with Os-W alloy. In electron gun, the dispenser cathode coated with dual-layer has pulse current density of 30 A/cm 2 and life of more than 800 h.

  13. A new dispenser cathode with dual-layer

    The emission and surface characteristics of the dispenser cathode coated with Os-W alloy and that coated with Os-W/Re are studied and compared. The dispenser cathode coated with Os-W/Re has been applied in electron gun measurement system for making measurement of higher emission current and life test. We called the cathode coated with Os-W/Re as the cathode with dual-layer. It is found that the dispenser cathode coated with dual-layer has higher current density than that coated only with Os-W alloy. After being activated, the cathode coated with dual-layer presents ternary composition on the surface of it. The W surface composition does not rise with time comparing with that of the cathode coated with Os-W alloy. In electron gun, the dispenser cathode coated with dual-layer has pulse current density of 30 A/cm2 and life of more than 800 h

  14. Ask Your Doctor or Pharmacist! On the Effect of Self-Dispensing Physicians on Pharmaceutical Coverage

    Bannert, Matthias; Iselin, David

    2015-01-01

    In most developed countries drugs are dispensed to patients through physicians and pharmacists. This paper studies the effects of allowing doctors to directly dispense drugs to patients (self-dispensation) on pharmaceutical coverage. We use a Swiss dataset in our empirical analysis because Switzerland's federalist legislation allows us to study self-dispensing and non-self-dispensing regimes alike. We add location information obtained from Google Geocoding services to our dataset in order to ...

  15. Application of basic pharmacology and dispensing practice of antibiotics in accredited drug-dispensing outlets in Tanzania

    2013-01-01

    Background Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs) in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, or duka la dawa baridi (DLDBs), in Tanzania. Methodology This was a cross-sectional study that was conducted in ADDOs and DLDBs. A simulated client method for data collection was used, and a total of 85 ADDOs, located in Mvomero, Kilombero, and Morogoro rural districts, were com...

  16. Application of basic pharmacology and dispensing practice of antibiotics in accredited drug-dispensing outlets in Tanzania

    Minzi, Omary

    2013-01-01

    OM Minzi,1 VS Manyilizu21Unit of Pharmacology and Therapeutics, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania, 2Logistics System Strengthening Unit, John Snow Inc, Dar es Salaam, TanzaniaBackground: Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs) in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, or duka la dawa baridi (DLDBs), in Tanzan...

  17. Improvement of optical and acoustical technologies for the protection: Project IMOTEP: Network of heterogeneous sensor types for the protection of camps or mobile troops

    Hengy, Sébastien; Laurenzis, Martin; Zimpfer, Véronique; Schneider, Armin

    2014-10-01

    Snipers have emerged as a major threat to troops in recent conflicts. To reduce this menace, the objective of the French- German Research Institute of Saint Louis (ISL) research project "IMOTEP" is to improve the detection of snipers on the battlefield. Our basic approach is to combine several sources of information for a fast and appropriate reaction when an unusual signal (e.g. a flash or a shot) is detected. The project includes several technologies developed at ISL: acoustical detection, fusion of distributed sensor network data, active imaging and 3D audio communication. The protection of camps, convoys or dismounted soldiers rests on a distributed acoustical sensor network that detects and localizes sniper attacks. An early estimation of the threat position is transmitted through a network to an active imaging system in order to confirm and refine this position by 3D imaging. The refined position is then sent to the control center which generates an alert message that displays the threat position using two formats: a tactical map and a 3D audio signal. In addition, the camp is protected by an ad-hoc sensor network used for intruder detection.

  18. Acoustic fault injection tool (AFIT)

    Schoess, Jeffrey N.

    1999-05-01

    On September 18, 1997, Honeywell Technology Center (HTC) successfully completed a three-week flight test of its rotor acoustic monitoring system (RAMS) at Patuxent River Flight Test Center. This flight test was the culmination of an ambitious 38-month proof-of-concept effort directed at demonstrating the feasibility of detecting crack propagation in helicopter rotor components. The program was funded as part of the U.S. Navy's Air Vehicle Diagnostic Systems (AVDS) program. Reductions in Navy maintenance budgets and available personnel have dictated the need to transition from time-based to 'condition-based' maintenance. Achieving this will require new enabling diagnostic technologies. The application of acoustic emission for the early detection of helicopter rotor head dynamic component faults has proven the feasibility of the technology. The flight-test results demonstrated that stress-wave acoustic emission technology can detect signals equivalent to small fatigue cracks in rotor head components and can do so across the rotating articulated rotor head joints and in the presence of other background acoustic noise generated during flight operation. During the RAMS flight test, 12 test flights were flown from which 25 Gbyte of digital acoustic data and about 15 hours of analog flight data recorder (FDR) data were collected from the eight on-rotor acoustic sensors. The focus of this paper is to describe the CH-46 flight-test configuration and present design details about a new innovative machinery diagnostic technology called acoustic fault injection. This technology involves the injection of acoustic sound into machinery to assess health and characterize operational status. The paper will also address the development of the Acoustic Fault Injection Tool (AFIT), which was successfully demonstrated during the CH-46 flight tests.

  19. Radiation acoustics

    Lyamshev, Leonid M

    2004-01-01

    Radiation acoustics is a developing field lying at the intersection of acoustics, high-energy physics, nuclear physics, and condensed matter physics. Radiation Acoustics is among the first books to address this promising field of study, and the first to collect all of the most significant results achieved since research in this area began in earnest in the 1970s.The book begins by reviewing the data on elementary particles, absorption of penetrating radiation in a substance, and the mechanisms of acoustic radiation excitation. The next seven chapters present a theoretical treatment of thermoradiation sound generation in condensed media under the action of modulated penetrating radiation and radiation pulses. The author explores particular features of the acoustic fields of moving thermoradiation sound sources, sound excitation by single high-energy particles, and the efficiency and optimal conditions of thermoradiation sound generation. Experimental results follow the theoretical discussions, and these clearl...

  20. Time reversal signal processing in acoustic emission testing

    Převorovský, Zdeněk; Krofta, Josef; Kober, Jan; Dvořáková, Zuzana; Chlada, Milan

    Brno: University of Technology, 2014. s. 10-11. ISBN 978-80-214-5019-6. [European Conference on Non-Destructive Testing (ECNDT 2014) /11./. 06.10.2014-10.10.2014, Praha] Institutional support: RVO:61388998 Keywords : acoustic emission (AE) * ultrasonic testing (UT) * signal processing * source location * time reversal acoustics * acoustic emission * signal processing and transfer Subject RIV: BI - Acoustics

  1. Acoustic black holes

    Visser, M

    1999-01-01

    Acoustic propagation in a moving fluid provides a conceptually clean and powerful analogy for understanding black hole physics. As a teaching tool, the analogy is useful for introducing students to both General Relativity and fluid mechanics. As a research tool, the analogy helps clarify what aspects of the physics are kinematics and what aspects are dynamics. In particular, Hawking radiation is a purely kinematical effect, whereas black hole entropy is intrinsically dynamical. Finally, I discuss the fact that with present technology acoustic Hawking radiation is almost experimentally testable.

  2. 声波清灰技术的理论研究与仿真%Simulation and Theoretical Study on Acoustic Wave Ash %learing Technology

    王涌; 郑博闻; 王威

    2011-01-01

    The frequency selecting of wave and energy controlling are the main problems in acoustic wave ash clearing technology. We found that soud intensity is concerned with the frequency of sound generator and the temperature of fluid gas when using the technology. In order to improve the effect of the technology, we built a mathematic model based on the acoustic wave ash clearing technology, and carried out some analyses on theory. Aim to reach the max of sound intensity, the temperature of fluid gas and the frequency of sound generator were improved optimally. The result shows that by Matlab simulating, 200Hz is considered the best frequency for sound intensity between 20 and 200 Hz. And between 0 and 100℃, 0℃ is considered the best the temperature of fluid gas for sound intensity. With the increase of the temperature, the sound intensity decreased. If we increase the frequency, the sound intensity increases evidently. It is very meaningful to research the sound clearing technology of the ESP.%研究声波清灰优化控制除灰效果,能量的控制和频率的选择是目前声波清灰技术研究过程中存在的主要问题.针对声波清灰技术在使用时,声强主要受到声波频率和气体温度因素的影响.为了改善声波清灰技术的效率,对声波清灰技术进行了数学建模和理论研究分析,取得了声强最佳时的气体温度值和声波发生器频率值.在Matlab上仿真结果表明:在20-200Hz范围内,200Hz是声强最大的频率,在0-100℃下,气体温度为O℃时,声强达到最大值.从能量仿真分析结果表明,最佳声频会使声波清灰效果最好.

  3. Acoustics waves and oscillations

    Sen, S.N.

    2013-01-01

    Parameters of acoustics presented in a logical and lucid style Physical principles discussed with mathematical formulations Importance of ultrasonic waves highlighted Dispersion of ultrasonic waves in viscous liquids explained This book presents the theory of waves and oscillations and various applications of acoustics in a logical and simple form. The physical principles have been explained with necessary mathematical formulation and supported by experimental layout wherever possible. Incorporating the classical view point all aspects of acoustic waves and oscillations have been discussed together with detailed elaboration of modern technological applications of sound. A separate chapter on ultrasonics emphasizes the importance of this branch of science in fundamental and applied research. In this edition a new chapter ''Hypersonic Velocity in Viscous Liquids as revealed from Brillouin Spectra'' has been added. The book is expected to present to its readers a comprehensive presentation of the subject matter...

  4. RUN TO RUN CONTROL OF TIME-PRESSURE DISPENSING SYSTEM

    Zhao Yixiang; Li Hanxiong; Ding Han; Xiong Youlun

    2004-01-01

    In electronics packaging the time-pressure dispensing system is widely used to squeeze the adhesive fluid in a syringe onto boards or sub-strates with the pressurized air.However,complexity of the process,which includes the air-fluid coupling and the nonlinear uncertainties,makes it diffi-cult to have a consistent process per-formance.An integrated dispensing process model is first introduced and then its input-output regression rela-tionship is used to design a run to run control methodology for this process.The controller takes EWMA scheme and its stability region is given.Ex-perimental results verify the effective-ness of the proposed run to run control method for dispensing process.

  5. Measurement and analysis of thermal photoemission from a dispenser cathode

    Jensen, Kevin L.; Feldman, Donald W.; Virgo, Matt; O'Shea, Patrick G.

    2003-08-01

    Photocathodes for free electron lasers (FELs) are required to produce nano-Coulomb pulses in picosecond time scales with demonstrable reliability, lifetime, and efficiency. Dispenser cathodes, traditionally a rugged and long-lived thermionic source, are under investigation to determine their utility as a photocathode and have shown promise. The present study describes theoretical models under development to analyze experimental data from dispenser cathodes and to create predictive time-dependent models to predict their performance as an FEL source. Here, a steady-state model of a dispenser cathode with partial coverage of a low work function coating and surface nonuniformity is developed. Quantitative agreement is found for experimental data, especially with regard to temperature, field, laser intensity, and quantum efficiency versus laser wavelength dependence. In particular, for long wavelength incident lasers of sufficient intensity, the majority of the absorbed energy heats the electron gas and background lattice, and photoemission from the heated electron distribution constitutes the emitted current.

  6. Battlefield acoustics

    Damarla, Thyagaraju

    2015-01-01

    This book presents all aspects of situational awareness in a battlefield using acoustic signals. It starts by presenting the science behind understanding and interpretation of sound signals. The book then goes on to provide various signal processing techniques used in acoustics to find the direction of sound source, localize gunfire, track vehicles, and detect people. The necessary mathematical background and various classification and fusion techniques are presented. The book contains majority of the things one would need to process acoustic signals for all aspects of situational awareness in one location. The book also presents array theory, which is pivotal in finding the direction of arrival of acoustic signals. In addition, the book presents techniques to fuse the information from multiple homogeneous/heterogeneous sensors for better detection. MATLAB code is provided for majority of the real application, which is a valuable resource in not only understanding the theory but readers, can also use the code...

  7. Acoustic telemetry

    National Oceanic and Atmospheric Administration, Department of Commerce — To determine movements of green turtles in the nearshore foraging areas, we deployed acoustic tags and determined their movements through active and passive...

  8. Acoustics Research

    National Oceanic and Atmospheric Administration, Department of Commerce — Fisheries acoustics data are collected from more than 200 sea-days each year aboard the FRV DELAWARE II and FRV ALBATROSS IV (decommissioned) and the FSV Henry B....

  9. Acoustics Discipline Overview

    Envia, Edmane; Thomas, Russell

    2007-01-01

    As part of the Fundamental Aeronautics Program Annual Review, a summary of the progress made in 2007 in acoustics research under the Subsonic Fixed Wing project is given. The presentation describes highlights from in-house and external activities including partnerships and NRA-funded research with industry and academia. Brief progress reports from all acoustics Phase 1 NRAs are also included as are outlines of the planned activities for 2008 and all Phase 2 NRAs. N+1 and N+2 technology paths outlined for Subsonic Fixed Wing noise targets. NRA Round 1 progressing with focus on prediction method advancement. NRA Round 2 initiating work focused on N+2 technology, prediction methods, and validation. Excellent partnerships in progress supporting N+1 technology targets and providing key data sets.

  10. Dispensing physicians and prescribing pharmacists: economic considerations for the UK.

    Ryan, M; Bond, C

    1994-01-01

    Recent years have seen an increase in the number of dispensing physicians in the UK. There have also been suggestions that legislation restricting certain drugs to prescription-only availability should be relaxed and that pharmacists should take a more active role in the provision of drugs. General medical practitioners and pharmacists have common ancestry in the medieval spicers, who dispensed medicines and offered medical advice. Rural practitioners have been allowed to dispense drugs since 1911. Physician dispensing can benefit patients via savings in time and the monetary cost of visiting a pharmacist, but it restricts drug choice, can compromise safety, and encourages overprescribing except for physicians with drugs budgets. The effects of physician dispensing on government costs are not yet clear. Over-the-counter (OTC) purchase can save patients the cost of a physician visit and reduce drug costs to some patients, but it can also provide an incentive to pharmacists to profit twice from a drug, at government expense. Switching drugs from prescription-only to OTC reduces the government drug bill, but provides an incentive to pharmacists to overprescribe, and may not be as safe for patients. Liberalising prescribing by doctors would discourage community pharmacies which provide an advisory service to patients. Liberalising OTC switches would reduce opportunistic assessment of patients by doctors and could compromise patient safety. Separation of physician and pharmacist functions is probably safer for patients. It is concluded that the current situation in the UK, whereby most dispensing is done by pharmacists, is the preferred option other than for those patients who do not live within easy access of a pharmacy. A reassessment of the legal status of drugs and subsequent OTC switch of drugs used to treat minor self-limiting illnesses is also favoured. PMID:10146862

  11. Dispensing practice of prescribed medicines in the private pharmacies in urban areas of Tanzania

    A R Kamuhabwa

    2015-01-01

    Full Text Available A descriptive cross-sectional study was conducted to assess quality of dispensing and knowledge of dispensers in 206 private retail pharmacies. The study was conducted in Dar es Salaam, Tanzania between September 2011 and April 2012. Patient simulation (mystery shopper approach was used to assess dispensing skills of drug dispensers for prescription only medicines. In assessing dispensing skills, a 7-days course of metronidazole tablets was bought from each pharmacy. The knowledge of drug dispenser's regarding dispensing of prescription only medicines was assessed through focus group discussions and interviews. Majority (70.4% of drug dispensers were not trained pharmaceutical personnel. The level of dispensing skills ranged from low (25.7% to medium (70.4%. Majority of drug dispensers had low (11.4% to medium (83.2% levels of knowledge about dispensing of 'prescription only' medicines. From these findings, it is recommended that the national Pharmacy Council should ensure that prescription only medicines are dispensed by trained pharmaceutical personnel. On job training and continuing professional development should also be emphasized to build capacity of drug dispensers.

  12. Dispensing Practice of Prescribed Medicines in the Private Pharmacies in Urban Areas of Tanzania.

    Kamuhabwa, A R; Ignace, A M

    2015-01-01

    A descriptive cross-sectional study was conducted to assess quality of dispensing and knowledge of dispensers in 206 private retail pharmacies. The study was conducted in Dar es Salaam, Tanzania between September 2011 and April 2012. Patient simulation (mystery shopper) approach was used to assess dispensing skills of drug dispensers for prescription only medicines. In assessing dispensing skills, a 7-days course of metronidazole tablets was bought from each pharmacy. The knowledge of drug dispenser's regarding dispensing of prescription only medicines was assessed through focus group discussions and interviews. Majority (70.4%) of drug dispensers were not trained pharmaceutical personnel. The level of dispensing skills ranged from low (25.7%) to medium (70.4%). Majority of drug dispensers had low (11.4%) to medium (83.2%) levels of knowledge about dispensing of 'prescription only' medicines. From these findings, it is recommended that the national Pharmacy Council should ensure that prescription only medicines are dispensed by trained pharmaceutical personnel. On job training and continuing professional development should also be emphasized to build capacity of drug dispensers. PMID:26798168

  13. Plasma processes inside dispenser hollow cathodes

    Mikellides, Ioannis G.; Katz, Ira; Goebel, Dan M.; Polk, James E.; Jameson, Kristina K.

    2006-06-01

    A two-dimensional fluid model of the plasma and neutral gas inside dispenser orificed hollow cathodes has been developed to quantify plasma processes that ultimately determine the life of the porous emitters inserted in these devices. The model self-consistently accounts for electron emission from the insert as well as for electron and ion flux losses from the plasma. Two cathodes, which are distinctively different in size and operating conditions, have been simulated numerically. It is found that the larger cathode, with outer tube diameter of 1.5cm and orifice diameter of 0.3cm, establishes an effective emission zone that spans approximately the full length of the emitter when operated at a discharge current of 25A and a flow rate of 5.5sccm. The net heating of the emitter is caused by ions that are produced by ionization of the neutral gas inside the tube and are then accelerated by the sheath along the emitter. The smaller cathode, with an outer diameter of 0.635cm and an orifice diameter of 0.1cm, does not exhibit the same operational characteristics. At a flow rate of 4.25sccm and discharge current of 12A, the smaller cathode requires 4.5 times the current density near the orifice and operates with more than 6 times the neutral particle density compared to the large cathode. As a result, the plasma particle density is almost one order of magnitude higher compared to the large cathode. The plasma density in this small cathode is high enough such that the Debye length is sufficiently small to allow "sheath funneling" into the pores of the emitter. By accessing areas deeper into the insert material, it is postulated that the overall emission of electrons is significantly enhanced. The maximum emission current density is found to be about 1A/mm2 in the small cathode, which is about one order of magnitude higher than attained in the large cathode. The effective emission zone in the small cathode extends to about 15% of the emitter length only, and the power

  14. Plasma processes inside dispenser hollow cathodes

    A two-dimensional fluid model of the plasma and neutral gas inside dispenser orificed hollow cathodes has been developed to quantify plasma processes that ultimately determine the life of the porous emitters inserted in these devices. The model self-consistently accounts for electron emission from the insert as well as for electron and ion flux losses from the plasma. Two cathodes, which are distinctively different in size and operating conditions, have been simulated numerically. It is found that the larger cathode, with outer tube diameter of 1.5 cm and orifice diameter of 0.3 cm, establishes an effective emission zone that spans approximately the full length of the emitter when operated at a discharge current of 25 A and a flow rate of 5.5 sccm. The net heating of the emitter is caused by ions that are produced by ionization of the neutral gas inside the tube and are then accelerated by the sheath along the emitter. The smaller cathode, with an outer diameter of 0.635 cm and an orifice diameter of 0.1 cm, does not exhibit the same operational characteristics. At a flow rate of 4.25 sccm and discharge current of 12 A, the smaller cathode requires 4.5 times the current density near the orifice and operates with more than 6 times the neutral particle density compared to the large cathode. As a result, the plasma particle density is almost one order of magnitude higher compared to the large cathode. The plasma density in this small cathode is high enough such that the Debye length is sufficiently small to allow 'sheath funneling' into the pores of the emitter. By accessing areas deeper into the insert material, it is postulated that the overall emission of electrons is significantly enhanced. The maximum emission current density is found to be about 1 A/mm2 in the small cathode, which is about one order of magnitude higher than attained in the large cathode. The effective emission zone in the small cathode extends to about 15% of the emitter length only, and the

  15. Overcoming Barriers to the Implementation of a Pharmacy Bar Code Scanning System for Medication Dispensing: A Case Study

    Nanji, Karen C.; Cina, Jennifer; Patel, Nirali; Churchill, William; Gandhi, Tejal K.; Poon, Eric G.

    2009-01-01

    Technology has great potential to reduce medication errors in hospitals. This case report describes barriers to, and facilitators of, the implementation of a pharmacy bar code scanning system to reduce medication dispensing errors at a large academic medical center. Ten pharmacy staff were interviewed about their experiences during the implementation. Interview notes were iteratively reviewed to identify common themes. The authors identified three main barriers to pharmacy bar code scanning s...

  16. Integration of BST varactors with surface acoustic wave device by film transfer technology for tunable RF filters

    This paper presents a film transfer process to integrate barium strontium titanate (BST) metal–insulator–metal (MIM) structures with surface acoustic wave (SAW) devices on a lithium niobate (LN) substrate. A high-quality BST film grown on a Si substrate above 650 °C was patterned into the MIM structures, and transferred to a LN substrate below 130 °C by Ar-plasma-activated Au–Au bonding and the Si lost wafer process. Simple test SAW devices with the transferred BST variable capacitors (VCs) were fabricated and characterized. The resonance frequency of a one-port SAW resonator with the VC connected in series changed from 999 to 1018 MHz, when a dc bias voltage of 3 V was applied to the VC. Although the observed frequency tuning range was smaller than expected due to the degradation of BST in the process, the experimental result demonstrated that a tunable SAW filter with the transferred BST VCs was feasible. (paper)

  17. Frequency, types, and potential clinical significance of medication-dispensing errors

    Xavier Bohand; Laurent Simon; Eric Perrier; Hélène Mullot; Leslie Lefeuvre; Christian Plotton

    2009-01-01

    INTRODUCTION AND OBJECTIVES: Many dispensing errors occur in the hospital, and these can endanger patients. The purpose of this study was to assess the rate of dispensing errors by a unit dose drug dispensing system, to categorize the most frequent types of errors, and to evaluate their potential clinical significance. METHODS: A prospective study using a direct observation method to detect medication-dispensing errors was used. From March 2007 to April 2007, “errors detected by pharmacists” ...

  18. 40 CFR 86.1246-96 - Fuel dispensing spitback procedure.

    2010-07-01

    ...) Evaporative Emission Test Procedures for New Gasoline-Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.1246-96 Fuel dispensing spitback procedure. (a) The... or methanol. The bag shall be designed and used so that liquid fuel does not spit back onto...

  19. 21 CFR 200.50 - Ophthalmic preparations and dispensers.

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Ophthalmic preparations and dispensers. 200.50... (CONTINUED) DRUGS: GENERAL GENERAL Requirements for Specific Classes of Drugs § 200.50 Ophthalmic... intended for ophthalmic use, including preparations for cleansing the eyes, should be sterile. It...

  20. 14 CFR 23.1447 - Equipment standards for oxygen dispensing units.

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Equipment standards for oxygen dispensing... Equipment Miscellaneous Equipment § 23.1447 Equipment standards for oxygen dispensing units. If oxygen... occupant for whom supplemental oxygen is to be supplied. Each dispensing unit must: (1) Provide...

  1. 14 CFR 25.1447 - Equipment standards for oxygen dispensing units.

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Equipment standards for oxygen dispensing... § 25.1447 Equipment standards for oxygen dispensing units. If oxygen dispensing units are installed... supplemental oxygen is to be supplied. Units must be designed to cover the nose and mouth and must be...

  2. 46 CFR 105.90-1 - Existing commercial fishing vessels dispensing petroleum products.

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Existing commercial fishing vessels dispensing petroleum... AND MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Existing Commercial Fishing Vessels Dispensing Petroleum Products § 105.90-1 Existing commercial fishing vessels...

  3. 46 CFR 105.05-1 - Commercial fishing vessels dispensing petroleum products.

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Commercial fishing vessels dispensing petroleum products... MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Application § 105.05-1 Commercial fishing vessels dispensing petroleum products. (a) The provisions of this part, with the exception...

  4. 46 CFR 105.45-1 - Loading or dispensing petroleum products.

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Loading or dispensing petroleum products. 105.45-1... VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Special Operating Requirements § 105.45-1 Loading or dispensing petroleum products. (a) A commercial fishing vessel must have aboard a letter...

  5. The Galileo IOV Dispenser System- Design, Development & Verification

    Thompson, S. P.; Andersson, G.; Davies, W.; Plaza, M. A.

    2012-07-01

    On October 21st, 2011, lifting off from the ELS launch site in French Guiana, a Soyuz ST-B and FREGAT upper stage, carried the first two Galileo IOV spacecraft on a 3-hour 49-minute flight and successfully injected the 2 Galileo Navigation spacecraft into a circular medium-Earth orbit. The Dispenser System, the subject of this paper, is the equipped launch vehicle hardware mated directly to the FREGAT upper stage and built specifically to carry 2 Galileo IOV spacecraft during all ground and flight operations up to the moment of separation. The Dispenser System was purposely built for the Galileo IOV missions under European Space Agency and Arianespace contract. The prime contractor was selected to be RUAG Space in Sweden (Linköping) for all Dispenser “System and Management” activities and with subcontracts placed to RUAG Space in Switzerland (Zurich) for the Dispenser “Structure” and EADS CASA Spain (Madrid) for the “Hold Down and Release System” (HRS) hardware. The “Structure” is designed to transfer ground and flight loads between the spacecraft and the Launch Vehicle. The upper part, an aluminium sandwich box-type structure, interfaces with the satellites, whereas the lower part transitions to a lower frame, via a CFRP strut arrangement, to interface with the FREGA T upper stage. The spacecraft separation sub-system is composed of two sets of four low- shock “HRS” units and four “pushers” enabling to firmly hold the satellites during ground and flight operations and to release them when ordered by the Launch Vehicle. The Dispenser System also comprises an electrical sub-system and MLI. This paper summarises the overall Design, Development and Verification activities leading to the Qualification of the Dispenser System hardware. This will include the Structure and HRS contribution to the overall System Qualification. An overview of the System hardware will be described along with DDV logic, some key analysis performed and several of the

  6. Acoustic emission

    This paper is related to our activities on acoustic emission (A.E.). The work is made with different materials: metals and fibre reinforced plastics. At present, acoustic emission transducers are being developed for low and high temperature. A test to detect electrical discharges in electrical transformers was performed. Our experience in industrial tests to detect cracks or failures in tanks or tubes is also described. The use of A.E. for leak detection is considered. Works on pattern recognition of A.E. signals are also being performed. (Author)

  7. Anisotropic and Negative Acoustic Index Metamaterials

    Fok, Lee Ren

    2010-01-01

    Microstructured materials are used in material science and engineering to attain desired material properties. Acoustic metamaterials are a rapidly growing area in this field of engineered materials that use deep subwavelength microstructures to attain exotic acoustic properties unavailable in nature. These properties, such as negative acoustic index, allow unprecedented capabilities such as sub-diffraction limit resolution, which have the potential to greatly improve existing technologies l...

  8. Antibiotics dispensing for URTIs by community pharmacists and general medical practitioners in Penang, Malaysia: A comparative study using simulated patients

    Alabid, Alamin Hassan M.A.; Ibrahim, Mohamed Izham Mohamed; Hassali, Mohamed Azmi

    2014-01-01

    Background: In Malaysia, doctors in private clinics (often called dispensing doctors) are permitted to dispense medicines. This potentially may compromise rational dispensing of medicines in general and antibiotics in particular. Aim: This study explored, assessed and compared dispensing of antibiotics between Community Pharmacist (CP) and General Practitioners (GPs) regarding symptomatic diagnosis, antibiotic categories, adherence to therapeutic doses and promotion of generic antibiotics...

  9. Fabrication and Measurement of Low Work Function Cesiated Dispenser Photocathodes

    Moody, Nathan A; Jensen, Kevin

    2005-01-01

    Photoinjector performance is a limiting factor in the continued development of high powered FELs and electron beam-based accelerators. Presently available photocathodes are plagued with limited efficiency and short lifetime in an RF-gun environment, due to contamination or evaporation of a photosensitive surface layer. An ideal photocathode should have high efficiency at long wavelengths, long lifetime in practical vacuum environments, and prompt emission. Cathodes with high efficiency typically have limited lifetime, and vice versa, and the needs of the photocathode are generally at odds with those of the drive laser. A potential solution is the low work function dispenser cathode, where lifetime issues are overcome by periodic in situ regeneration that restores the photosensitive surface layer, analogous to those used in the microwave power tube industry. This work reports on the fabrication techniques and performance of cesiated metal photocathodes and cesiated dispenser cathodes, with a focus on understan...

  10. Testing and Performance Analysis on Air Conditioner cum Water Dispenser

    Dr. U. V.Kongrea , A. R. Chiddarwarb , P. C. Dhumatkarc , A.B.Aris

    2013-04-01

    Full Text Available The work on developing the heat pumps for space conditioning and water heating has been gone for half a century. The earlier water heating pumps and air to water heating pumps gives only hot water and space conditioning. But in this air conditioning cum water dispenser we get hot and cold water with hot and cold air, thus the system becomes multifunctional. The actual cycles and operating conditions for air and water cycle present in this paper. The paper introduced basic design principles and the test analysis performed in the laboratory. The test results were found encouraging especially the parameters of dispenser output along with air conditioner. The paper also introduced comfort conditions and suitable coefficient of performance with respect to atmospheric condition, without sacrificing the air conditioning output

  11. Technology research and development for acoustic subbottom survey in deep sea%声学地层剖面深水探测研究与开发

    丁维凤; 李家彪; 苏希华; 张济博; 蒋维杰; 韩富江

    2015-01-01

    Detailed survey of acoustic subbottom is important for deep ocean geological exploration and resource ex-ploitation.Compared to survey in shallow ocean water,deep sea survey faced some serious problems such as energy strongly attenuation,long reflection time series and large digital data size,the vertical stratigraphic resolution reduc-tion,and low transverse space coverage.In order to resolving these problems,main instrument manufactures in the world adopted different possible methods.For example,resampling long reflection time series can decrease the data size,but it strongly reduce vertical stratigraphic resolution.Taking MultiPing technology can solve the transverse space coverage well,but its variable depth range acquisition by seafloor reflection tracking will cause serious jump-ing off in reflection events,or it cannot get the correct seafloor reflection depth by acquisition with MultiPing trans-mitting interval.This study further independently developed some related technologies,and correctly solved the re-flection events'jumping off,and got the recording time delay in computing the deep seafloor depth.All these tech-nologies obtained in the present study will provide some technical support for future acoustic subbottom detailed survey in deep sea.%深水浅部地层精细探测是深海地质勘探与资源开发的重要调查内容。与浅水海域声学地层剖面探测相比,深水地层剖面探测会遇到严重的能量衰减、大数据量长时间反射序列采样、纵向地层分辨率降低以及横向空间覆盖率偏稀等问题,为解决这些问题,国外仪器商采用了不同的方法。采取重采样减少数据量会严重影响纵向分辨率;采取 MultiPing 技术可以很好解决横向空间覆盖率问题,但多 Ping 接收采用海底追踪变深度范围采集会造成反射同相轴跳跃突变,或采用短时间间隔采集会造成回波数据无法准确计算海底深度。为了解决这些技术问题

  12. 多路水声信号抗串漏检测技术仿真%Technology simulation study on detection of anti-cross-leakage from multi-path underwater acoustic signals

    杜召平; 张强; 刘百峰

    2012-01-01

    根据水下多目标定位系统水声通道特点和系统海上试验实际应用情况,建立系统多路合作水声信号检测处理仿真模型.仿真表明:采用FIR宽带滤波器、Notch滤波器组和瞬时频率方差序列等水声信号处理技术,能有效克服系统水声通道串漏、高斯白噪声和鱼雷寻的噪声对信号检测的影响,实现系统对多路合作水声信号的检测处理.%A simulation model is established for the system to detect and process multi-path cooperative underwater acoustic signals according to the characteristic of the underwater acoustic channels for an underwater multi-target positioning system and the practical application for the system sea trial. The simulation indicates that utilizing underwater acoustic signal processing technology, such as FIR wideband filter, Notch filter group and instantaneous frequency variance sequence etc, influences on signal detection can be overcome for cross-leakage from the underwater acoustic channels of the system, Gauss white noises and torpedo homing noises. Detection and processing of multi-path cooperative underwater signals can be implemented by the system.

  13. Justice dispensation through the alternative dispute resolution system in India

    Krishna Agrawal

    2014-01-01

    The Law Commission of India in its 222nd report emphasized the need for Alternative Disputes Resolution (ADR) for the dispensation of justice, because the courts are inaccessible owing to various factors, e.g., poverty, social and political backwardness, illiteracy, ignorance, procedural formalities and inordinate delay in judgments. During the ancient period the disputes were resolved in an informal manner by neutral third persons or people’s court in villages and it continued till the middl...

  14. International Space Station USOS Potable Water Dispenser Development

    Shaw, Laura A.; Barreda, Jose L.

    2008-01-01

    The International Space Station (ISS) Russian Segment currently provides potable water dispensing capability for crewmember food and beverage rehydration. All ISS crewmembers rehydrate Russian and U.S. style food packages from this location. A new United States On-orbit Segment (USOS) Potable Water Dispenser (PWD) is under development. This unit will provide additional potable water dispensing capability to support an onorbit crew of six. The PWD is designed to provide incremental quantities of hot and ambient temperature potable water to U.S. style food packages. It will receive iodinated water from the Fuel Cell Water Bus in the U.S. Laboratory element. The unit will provide potable-quality water, including active removal of biocidal iodine prior to dispensing. A heater assembly contained within the unit will be able to supply up to 2.0 liters of hot water (65 to 93oC) every thirty minutes. This quantity will allow three to four crewmembers to rehydrate their food and beverages from this location during a single meal. The unit is designed to remain functional for up to ten years with replacement of limited life items such as filters. It will be the size of two stacked Shuttle Middeck lockers (approximately the size of two small suitcases) and integrated into a science payload rack in the U.S. Laboratory element. Providing potable-quality water at the proper temperature for food and beverage reconstitution is critical to maintaining crew health and well-being. The numerous engineering challenges as well as human factors and safety considerations during the concept, design, and prototyping are outlined in this paper.

  15. Continued Dispensing: what medications do patients believe should be available?

    Salem Hasn Abukres; Kreshnik Hoti; Jeffery David Hughes

    2015-01-01

    Background. Continued Dispensing (CD) is a new medication supply method for certain medications in Australia. It aims to prevent treatment interruption as a result of patients’ inability to obtain a new valid prescription. The only currently eligible patients for this service are statin and/or oral contraceptives users who have been using these medications for 6 months or more, have not utilized the CD method during the last 12 months, and cannot obtain an immediate appointment with the presc...

  16. Patient attitudes towards a new role for pharmacists: continued dispensing

    Abukres SH; Hoti K; Hughes JD

    2014-01-01

    Salem Hasn Abukres, Kreshnik Hoti, Jeffery David Hughes School of Pharmacy, Curtin Health and Innovation Research Institute, Curtin University, Perth, WA, Australia Background: In Australia, “continued dispensing” (CD) is a new model for supply of prescription medications. Under specific circumstances, community pharmacists are allowed to dispense a further one month supply of prescription only medications without a valid prescription. It allows continuation and treatment adhere...

  17. Work function measurements of dispenser cathodes by retarding potential method

    Khairnar, Rajendra S.; Chopra, A. K.

    1992-11-01

    The work function of dispenser cathode pellets has been determined by means of the retarding potential technique. A low-energy electron gun was fabricated which delivers a collimated beam of electrons on the pellet surface at normal incidence. The set up is calibrated by employing samples of known work function such as gold and tungsten, prior to determining the work function of the cathode pellets. This set up provides a rapid determination of the work function of cathode pellets.

  18. Direct-Dispense Polymeric Waveguides Platform for Optical Chemical Sensors

    Mohamad Hajj-Hassan

    2008-12-01

    Full Text Available We describe an automated robotic technique called direct-dispense to fabricate a polymeric platform that supports optical sensor arrays. Direct-dispense, which is a type of the emerging direct-write microfabrication techniques, uses fugitive organic inks in combination with cross-linkable polymers to create microfluidic channels and other microstructures. Specifically, we describe an application of direct-dispensing to develop optical biochemical sensors by fabricating planar ridge waveguides that support sol-gelderived xerogel-based thin films. The xerogel-based sensor materials act as host media to house luminophore biochemical recognition elements. As a prototype implementation, we demonstrate gaseous oxygen (O2 responsive optical sensors that operate on the basis of monitoring luminescence intensity signals. The optical sensor employs a Light Emitting Diode (LED excitation source and a standard silicon photodiode as the detector. The sensor operates over the full scale (0%-100% of O2 concentrations with a response time of less than 1 second. This work has implications for the development of miniaturized multisensor platforms that can be cost-effectively and reliably mass-produced.

  19. Acoustic methodology review

    Schlegel, R. G.

    1982-01-01

    It is important for industry and NASA to assess the status of acoustic design technology for predicting and controlling helicopter external noise in order for a meaningful research program to be formulated which will address this problem. The prediction methodologies available to the designer and the acoustic engineer are three-fold. First is what has been described as a first principle analysis. This analysis approach attempts to remove any empiricism from the analysis process and deals with a theoretical mechanism approach to predicting the noise. The second approach attempts to combine first principle methodology (when available) with empirical data to formulate source predictors which can be combined to predict vehicle levels. The third is an empirical analysis, which attempts to generalize measured trends into a vehicle noise prediction method. This paper will briefly address each.

  20. Acoustic lenses

    Acoustic lenses focus ultrasound to produce pencil-like beams with reduced near fields. When fitted to conventional (flat-faced) transducers, such lenses greatly improve the ability to detect and size defects. This paper describes a program developed to design acoustic lenses for use in immersion or contact inspection, using normal or angle beam mode with flat or curved targets. Lens surfaces are circular in geometry to facilitate machining. For normal beam inspection of flat plate, spherical or cylindrical lenses are used. For angle beam or curved surface inspections, a compound lens is required to correct for the extra induced aberration. Such a lens is aspherical with one radius of curvature in the plane of incidence, and a different radius of curvature in the plane perpendicular to the incident plane. The resultant beam profile (i.e., location of the acoustic focus, beam diameter, 6 dB working range) depends on the degree of focusing and the transducer used. The operating frequency and bandwidth can be affected by the instrumentation used. Theoretical and measured beam profiles are in good agreement. Various applications, from zone focusing used for defect sizing in thick plate, to line focusing for pipe weld inspection, are discussed

  1. In situ calibration of acoustic emission sensors

    Kober, Jan; Převorovský, Zdeněk

    Brno: University of Technology, Brno, 2015 - (Mazal, P.), s. 93-97 ISBN 978-80-214-5262-6. [International Workshop NDT in Progress /8./. Praha (CZ), 12.10.2015-14.10.2015] Institutional support: RVO:61388998 Keywords : standardisation * Acoustic Emission (AE) * time reversal * calibration * requency response Subject RIV: BI - Acoustics

  2. Acoustic scattering properties of freshwater invertebrates

    Frouzová, Jaroslava; Kubečka, Jan; Matěna, Josef

    Netherlands : Delft University of Technology, 2004 - (Simons, D.), s. 319-324 ISBN 90-5986-079-9. [European Conference on Underwater Acoustic /7./. Delft (NL), 05.07.2004-08.07.2004] R&D Projects: GA AV ČR(CZ) IAA6017201 Keywords : invertebrates * target strength Subject RIV: BI - Acoustics

  3. Applications of acoustics in insect pest management

    Acoustic technology has been applied for many years in studies of insect communication and in the monitoring of calling-insect population levels, geographic distributions, and diversity, as well as in the detection of cryptic insects in soil, wood, container crops, and stored products. Acoustic devi...

  4. Design and performance evaluation of a new jetting dispenser system using two piezostack actuators

    This paper presents a new jetting dispenser system which is adaptable to various packaging processes such as light emitting diode packaging and flip chip packaging. The proposed dispenser system is driven by piezostack actuators and a lever-hinge mechanism. In order to improve jetting performances such as accurate dispensed amount and adaptability to high viscosity fluid, two piezostack actuators are used. By activating the two actuators dually, the angular displacement of the lever can be controlled to produce a required motion of the needle. Firstly, the configuration and working principles of the proposed jetting system are explained, the design of the dispenser is then conducted and significant geometric dimensions of the dispenser are presented. In the design process, several operational requirements such as the maximum needle stroke, operational frequency, and amplification ratio of the lever-hinge are considered. The principal design parameters of the jetting dispenser system are determined from static and modal analysis using the finite element analysis. After obtaining the dimensional characteristics, the control logic for the dispensing operation is explained using a feed-forward controller. The piezostack-driven jetting dispenser system and control devices are then fabricated to evaluate the dispenser performance. It is shown experimentally that by changing the input voltage conditions, the amount of fluid dispensed by the proposed jetting system can be effectively controlled to achieve the desired jetting performance. (paper)

  5. Simulation and Experiment Research of Non-contact Micro-liquid Reagent Dispensing

    Yao Yufeng

    2013-05-01

    Full Text Available With the development of biological analytical techniques and high throughput screening techniques, a large number of automated biological agents dispensing systems are widely used in the field of life science research. Non-contact dispensing method characterized by its small dispensing volume, high dispensing precision and quick service speed which satisfies the requirements of biological agent’s distribution, becomes the mainstream dispensing method used in reagent dispensing systems. However, the difficult control way, complex system of non-contact dispensing method and its vulnerable dispensing process, which can be easily affected by characteristics of the agent, have hindered the application and development of the method. In this study, simulation model of the separation process of micro scale biological reagent are constructed in order to solve the above problems. The prerequisites of the non-contact dispensing method, the relationship between dispensing volume and precision and characteristics of reagents, formation of system and control parameters are researched through theoretical analysis and numerical simulations. The experiment results are quite consistent with the simulation results; therefore it well verifies the reliability of the modeling and simulation method and also lays a firm theoretical foundation for the system design of non-contact micro-liquid reagent distribution and control optimization.

  6. Study on Tracking and Positioning Technology of Mine Rising Trajectory by Underwater Acoustic Pulse Encoding%水雷上浮弹道水声脉冲编码跟踪定位技术研究

    杜召平; 刘百峰

    2013-01-01

    According to the ranging and positioning principle of synchronized underwater acoustic pulse, the positioning technology by underwater multi-channel GPS sonar buoy array _mine-borne 3D segment is used to track and position the rising mines.Multi-frequency underwater acoustic pulse encoded technology is used to expand transmitting period for underwater acoustic pulse.The problems are solved that measurement period is fuzzy and measurement data size is not enough.The mine-borne 3D segment designed by perception of mine states and energy-saving technology has functions on conversion of operational states and transmitting underwater acoustic signals for a long time.The simulated model for the system tracking and positioning accuracy is set up with spherical intersection positioning solution.Influences on the system positioning accuracy are predicted for the system synchronized accuracy, time-delay detection accuracy of underwater acoustic signals, GPS positioning accuracy, hydrophone position accuracy and measurement accuracy of sound velocity.The grounds are provided for the technology feasibility and the development of correlated series of measurement and control equipment.%根据同步水声脉冲测距定位原理,利用水下多信道GPS声纳浮标阵-雷载3D段定位技术,对上浮水雷进行跟踪定位.利用多频水声脉冲编码技术扩展水声脉冲发射周期,解决了测量周期模糊与测量数据量匮乏的问题.利用水雷状态感知和节能技术设计的雷载3D,段具有工作状态转换和长时间水声信号发射功能.利用球面交汇定位解法建立了系统跟踪定位精度仿真模型,通过仿真预测出系统同步精度、水声信号时延检测精度、GPS定位精度、水听器位置精度和声速测量精度对系统定位精度的影响,为此项技术的可行性和相关系列测控装备的研制提供了依据.

  7. Hydrogen Station Compression, Storage, and Dispensing Technical Status and Costs: Systems Integration

    Parks, G.; Boyd, R.; Cornish, J.; Remick, R.

    2014-05-01

    At the request of the U.S. Department of Energy Fuel Cell Technologies Office (FCTO), the National Renewable Energy Laboratory commissioned an independent review of hydrogen compression, storage, and dispensing (CSD) for pipeline delivery of hydrogen and forecourt hydrogen production. The panel was asked to address the (1) cost calculation methodology, (2) current cost/technical status, (3) feasibility of achieving the FCTO's 2020 CSD levelized cost targets, and to (4) suggest research areas that will help the FCTO reach its targets. As the panel neared the completion of these tasks, it was also asked to evaluate CSD costs for the delivery of hydrogen by high-pressure tube trailer. This report details these findings.

  8. Overcoming barriers to the implementation of a pharmacy bar code scanning system for medication dispensing: a case study.

    Nanji, Karen C; Cina, Jennifer; Patel, Nirali; Churchill, William; Gandhi, Tejal K; Poon, Eric G

    2009-01-01

    Technology has great potential to reduce medication errors in hospitals. This case report describes barriers to, and facilitators of, the implementation of a pharmacy bar code scanning system to reduce medication dispensing errors at a large academic medical center. Ten pharmacy staff were interviewed about their experiences during the implementation. Interview notes were iteratively reviewed to identify common themes. The authors identified three main barriers to pharmacy bar code scanning system implementation: process (training requirements and process flow issues), technology (hardware, software, and the role of vendors), and resistance (communication issues, changing roles, and negative perceptions about technology). The authors also identified strategies to overcome these barriers. Adequate training, continuous improvement, and adaptation of workflow to address one's own needs mitigated process barriers. Ongoing vendor involvement, acknowledgment of technology limitations, and attempts to address them were crucial in overcoming technology barriers. Staff resistance was addressed through clear communication, identifying champions, emphasizing new information provided by the system, and facilitating collaboration. PMID:19567797

  9. Physician drug dispensing in Switzerland: association on health care expenditures and utilization

    Trottmann, Maria; Frueh, Mathias; Telser, Harry; Reich, Oliver

    2016-01-01

    Background Several countries recently reassessed the roles of drug prescribing and dispensing, either by enlarging pharmacists’ rights to prescribe (e.g. the US and the United Kingdom) or by limiting physicians’ rights to dispense (e.g. Taiwan and South Korea). While integrating the two roles might increase supply and be convenient for patients, concern is that drug mark-ups incite providers to prescribe unnecessary drugs. We aimed to assess the association of physician dispensing (PD) in Swi...

  10. Regulations, Codes, and Standards (RCS) Template for California Hydrogen Dispensing Stations

    Rivkin, C.; Blake, C.; Burgess, R.; Buttner, W.; Post, M.

    2012-11-01

    This report explains the Regulations, Codes, and Standards (RCS) requirements for hydrogen dispensing stations in the State of California. The reports shows the basic components of a hydrogen dispensing station in a simple schematic drawing; the permits and approvals that would typically be required for the construction and operation of a hydrogen dispensing station; and a basic permit that might be employed by an Authority Having Jurisdiction (AHJ).

  11. Acoustic Monitoring for Spaceflight Vehicle Applications Project

    National Aeronautics and Space Administration — This SBIR will develop and demonstrate acoustic sensor technology enabling real-time, remotely performed measuring and monitoring of sound pressure levels and noise...

  12. Improvement of the positional dispensing in the washing machine MW 2001.

    Arce Quintana, José Luis; Lobaina, Reinaldo; Hernández Collado, Yanet; García Sardiñas, Raúl; Fernández Torres, Denis A; Puig Puig, Pedro

    2013-06-01

    This article is about how to improve the positional dispensing accuracy of low-volume (microliters) drops and to understand the factors affecting them. These same parameters can be investigated to reduce deleterious effects on dispensing performance. Many applications, such as those in immunoassay diagnostics, require accurate volumetric dispensing and are also less tolerant of other phenomena that cause the reagent to be located outside the target area of interest. In this article, we work with liquid inertia. This phenomenon is present in positional dispensing and affects its accuracy. The negative effect of liquid inertia is reduced by changing parameters such as pressure and the diameter of the involved conducts. PMID:23400949

  13. Guide to Permitting Hydrogen Motor Fuel Dispensing Facilities

    Rivkin, Carl [National Renewable Energy Lab. (NREL), Golden, CO (United States); Buttner, William [National Renewable Energy Lab. (NREL), Golden, CO (United States); Burgess, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-03-28

    The purpose of this guide is to assist project developers, permitting officials, code enforcement officials, and other parties involved in developing permit applications and approving the implementation of hydrogen motor fuel dispensing facilities. The guide facilitates the identification of the elements to be addressed in the permitting of a project as it progresses through the approval process; the specific requirements associated with those elements; and the applicable (or potentially applicable) codes and standards by which to determine whether the specific requirements have been met. The guide attempts to identify all applicable codes and standards relevant to the permitting requirements.

  14. Over-the-counter suboptimal dispensing of antibiotics in Uganda

    Mukonzo JK

    2013-08-01

    Full Text Available Jackson K Mukonzo,1,2 Proscovia M Namuwenge,1 Gildo Okure,3 Benjamin Mwesige,1 Olivia K Namusisi,4 David Mukanga4 1Center for Operational Research Africa, Kampala, Uganda; 2Department of Pharmacology and Therapeutics, 3School of Public Health, Makerere University, Kampala, Uganda; 4African Field Epidemiologist Network, Kampala, Uganda Background: Overuse and misuse of antibiotics is a serious global problem. While resistance to older antibiotics is increasing, development of newer molecules has stalled. Resistance to the existing antibiotics that is largely driven by their high-volume use is a global public health problem. Uganda is one of the countries where prescription-only drugs, including antibiotics, can be obtained over the counter. We determined the rate of antibiotic dispensing and use in Uganda. Methods: The study utilized a descriptive cross-sectional study design to determine the number of antibiotic "prescribed" daily doses per 1,000 clients. Data were collected from one health center II, eight general/district hospitals, one national referral hospital, and 62 registered community pharmacies. From each study site, data were collected for five consecutive days over the months of November 2011 to January 2012. Results: The overall antibiotic issue rate was 43.2%. Amoxicillin, metronidazole, ciprofloxacin, sulfamethoxazole–trimethoprim, cloxacillin, and ampicillin, belonging to the WHO anatomical therapeutic chemical classifications of penicillin with extended spectra, imidazole derivatives, fluoroquinolones, and sulfonamide–trimethoprim combinations, constituted 70% of the issued antibiotics. About 41% of antibiotics were issued over the counter. At community pharmacies, where 30% of antibiotic dispensing occurred, the number of prescribed daily doses/1,000 antibiotic clients was 4,169 compared to 6,220, 7,350 and 7,500 at general/district hospitals, the national referral hospital, and the health center, respectively. Conclusion

  15. Poisoning studies of an osmium-coated dispenser cathode

    The results of our studies on the reduction of the emission current from an osmium-alloy-coated dispenser cathode (derivative of the M cathode) due to exposure to various gases or vapors are reported. The primary interest of these studies is poisoning by chemical agents that might be encountered in the vacuum system of an induction linear accelerator. Of the constituents normally found in a tight unbaked vacuum chamber, the cathode is most sensitive to partial pressures of water vapor. Of the vapors studied which might be encountered in an induction accelerator, Freon was the most virulent poison

  16. Large area dispenser cathode applied to high current linac

    The paper introduced a dispenser cathode (411 M) which was 55 mm in diameter. A 200 kV long pulsed power generator with 2 μs flattop based on Marx-PEN and system with heat and voltage insulation were built. A 52 A space charge limited current was gained, when the temperature was 1165 degree C and the filament current was 18 A on the cathode and the voltage of the pulse was 75 kV at the cathode test stand. Experimental results show that the current values are consistent with the numerical simulation. The experiment reveals that the deflated gas will influence the cathode emission ability. (authors)

  17. Acoustic Neuroma Educational Video

    Full Text Available Educational Video Home What is an AN What is an Acoustic Neuroma? Identifying an AN Symptoms Acoustic Neuroma Keywords Educational Video ... for pre- and post-treatment acoustic neuroma patients. Home What is an AN What is an Acoustic ...

  18. Photoemission experiments of a large area scandate dispenser cathode

    Zhang Huang, E-mail: bamboobbu@hotmail.co [Institute of Fluid Physics, CAEP, P.O. Box 919-106, Mianyang 621900 (China); Liu Xingguang; Chen Yi; Chen Debiao; Jiang Xiaoguo; Yang Anmin; Xia Liansheng; Zhang Kaizhi; Shi Jinshui; Zhang Linwen [Institute of Fluid Physics, CAEP, P.O. Box 919-106, Mianyang 621900 (China)

    2010-09-21

    A 100-mm-diameter scandate dispenser cathode was tested as a photocathode with a 10 ns Nd:YAG laser (266 nm) on an injector test stand for linear induction accelerators. This thermionic dispenser cathode worked at temperatures ranging from room temperature to 930 {sup o}C (below or near the thermionic emission threshold) while the vacuum was better than 4x10{sup -7} Torr. The laser pulse was synchronized with a 120 ns diode voltage pulse stably and they were in single pulse mode. Emission currents were measured by a Faraday cup. The maximum peak current collected at the anode was about 100 A. The maximum quantum efficiency measured at low laser power was 2.4x10{sup -4}. Poisoning effect due to residual gas was obvious and uninterrupted heating was needed to keep cathode's emission capability. The cathode was exposed to air one time between experiments and recovered after being reconditioned. Photoemission uniformity of the cathode was also explored by changing the laser spot's position.

  19. Photoemission experiments of a large area scandate dispenser cathode

    Zhang, Huang; Liu, Xing-guang; Chen, Yi; Chen, De-biao; Jiang, Xiao-guo; Yang, An-min; Xia, Lian-sheng; Zhang, Kai-zhi; Shi, Jin-shui; Zhang, Lin-wen

    2010-09-01

    A 100-mm-diameter scandate dispenser cathode was tested as a photocathode with a 10 ns Nd:YAG laser (266 nm) on an injector test stand for linear induction accelerators. This thermionic dispenser cathode worked at temperatures ranging from room temperature to 930 °C (below or near the thermionic emission threshold) while the vacuum was better than 4×10 -7 Torr. The laser pulse was synchronized with a 120 ns diode voltage pulse stably and they were in single pulse mode. Emission currents were measured by a Faraday cup. The maximum peak current collected at the anode was about 100 A. The maximum quantum efficiency measured at low laser power was 2.4×10 -4. Poisoning effect due to residual gas was obvious and uninterrupted heating was needed to keep cathode's emission capability. The cathode was exposed to air one time between experiments and recovered after being reconditioned. Photoemission uniformity of the cathode was also explored by changing the laser spot's position.

  20. Photoemission experiments of a large area scandate dispenser cathode

    A 100-mm-diameter scandate dispenser cathode was tested as a photocathode with a 10 ns Nd:YAG laser (266 nm) on an injector test stand for linear induction accelerators. This thermionic dispenser cathode worked at temperatures ranging from room temperature to 930 oC (below or near the thermionic emission threshold) while the vacuum was better than 4x10-7 Torr. The laser pulse was synchronized with a 120 ns diode voltage pulse stably and they were in single pulse mode. Emission currents were measured by a Faraday cup. The maximum peak current collected at the anode was about 100 A. The maximum quantum efficiency measured at low laser power was 2.4x10-4. Poisoning effect due to residual gas was obvious and uninterrupted heating was needed to keep cathode's emission capability. The cathode was exposed to air one time between experiments and recovered after being reconditioned. Photoemission uniformity of the cathode was also explored by changing the laser spot's position.

  1. Use of acoustic vortices in acoustic levitation

    Cutanda Henriquez, Vicente; Santillan, Arturo Orozco; Juhl, Peter Møller

    2009-01-01

    Acoustic fields are known to exert forces on the surfaces of objects. These forces are noticeable if the sound pressure is sufficiently high. Two phenomena where acoustic forces are relevant are: i) acoustic levitation, where strong standing waves can hold small objects at certain positions...... of acoustical vortices uses an efficient numerical implementation based on the superposition of two orthogonal sound fields with a delay of 90° between them. It is shown that acoustic levitation and the use of acoustic vortices can be combined to manipulate objects in an efficient and controlled manner without......, counterbalancing their weight, and ii) acoustic vortices, spinning sound fields that can impinge angular momentum and cause rotation of objects. In this contribution, both force-creating sound fields are studied by means of numerical simulations. The Boundary Element Method is employed to this end. The simulation...

  2. The challenge of responsible dispensing: formal education versus professional practice

    Nadine Judith Bezzegh

    2011-03-01

    Full Text Available The aim of the present study was to evaluate the education of Pharmaceutical Technicians for the activity of responsible dispensing. Based on a questionnaire with open and closed questions, the study sought to characterize the students, identify knowledge and attitudes regarding the Rational Use of Medications while addressing the limits and possibilities of professional and ethical dispensing in practice. In addition, a group dynamics session - focus group - was held as a forum for debate on responsible dispensing. The results showed that students tended to be mature, currently employed and were predominately women. Displaying adequate knowledge on Rational Use of Medications and of the corresponding legislation, the students reported difficulties exercising compatible practice. While the diagnosis pointed to the need for student preparation to enable ethical dispensing, the Focus Group highlighted the possibility for inclusion of a forum for reflection and debate on the ethics of dispensing as part of the Pharmaceutical Technician training.O presente trabalho tem como proposta avaliar a formação do Técnico em Farmácia para o exercício da dispensação responsável. A partir de um questionário com perguntas fechadas e abertas, o estudo envolveu a caracterização dos alunos, a identificação de conhecimentos e atitudes em relação ao Uso Racional dos Medicamentos com vistas ao delineamento dos limites e possibilidades do exercício profissional ético na dispensação. Além disso, foi realizada uma dinâmica grupal - grupo focal - com o objetivo de apreciar a constituição de um espaço de reflexão sobre a dispensação responsável. Os resultados evidenciaram um alunato de maior idade, inserido no mercado de trabalho e predominância de mulheres. Dispondo de conhecimento adequado sobre o Uso Racional dos Medicamentos e da legislação correspondente os alunos fazem referência às dificuldades no exercício de uma pr

  3. Early work on fiber optic gyro technology at McDonnell Douglas and spinoffs leading to acoustic sensing, distributed sensing, and a secure fiber optic communication system

    Udd, Eric

    2006-08-01

    In the late 1970s the closed loop fiber optic gyro was invented and demonstrated at McDonnell Douglas Astronautics Company in Huntington Beach, California. This development was followed by a series of derivative inventions that included the Sagnac acoustic sensor, Sagnac distributed sensors and finally a Sagnac secure fiber optic communication system. This paper provides an overview of these developments.

  4. Acoustic multivariate condition monitoring - AMCM

    Rosenhave, P.E. [Vestfold College, Maritime Dept., Toensberg (Norway)

    1997-12-31

    In Norway, Vestfold College, Maritime Department presents new opportunities for non-invasive, on- or off-line acoustic monitoring of rotating machinery such as off-shore pumps and diesel engines. New developments within acoustic sensor technology coupled with chemometric data analysis of complex signals now allow condition monitoring of hitherto unavailable flexibility and diagnostic specificity. Chemometrics paired with existing knowledge yields a new and powerful tool for condition monitoring. By the use of multivariate techniques and acoustics it is possible to quantify wear and tear as well as predict the performance of working components in complex machinery. This presentation describes the AMCM method and one result of a feasibility study conducted onboard the LPG/C `Norgas Mariner` owned by Norwegian Gas Carriers as (NGC), Oslo. (orig.) 6 refs.

  5. Acoustic dispersive prism

    Hussein Esfahlani; Sami Karkar; Herve Lissek; Mosig, Juan R.

    2016-01-01

    The optical dispersive prism is a well-studied element, which allows separating white light into its constituent spectral colors, and stands in nature as water droplets. In analogy to this definition, the acoustic dispersive prism should be an acoustic device with capability of splitting a broadband acoustic wave into its constituent Fourier components. However, due to the acoustical nature of materials as well as the design and fabrication difficulties, there is neither any natural acoustic ...

  6. THE ORIGINS OF THE CASHLESS SOCIETY: CASH DISPENSERS, DIRECT TO ACCOUNT PAYMENTS AND THE DEVELOPMENT OF ON-LINE REAL-TIME NETWORKS, C.1965-1985

    Bernardo Bátiz-Lazo; Tobias Karlsson; Björn Thodenius

    2014-01-01

    This article explores the technological choices made at the dawn of the massification of retail finance. We describe and analyze the early development of electronic banking and the foundations of the cashless society through the experiences of organizations with similar governance in two different competitive environments — Swedish and British savings banks. We document how the adoption of direct-to-account wage deposits and the subsequent deployment of networks of cash dispensers interacted ...

  7. Device for manual aspiration and dispensing of radionuclide solutions in medicine

    This device for manual aspiration of dispensing of radionuclide solutions in medicine, particularly for transferring radionuclide solutions from closed bottles to syringes to be injected to patients or for subsequent dispensing into closed bottles, is safe and convenient to handle because any hand contact is avoided. (P.A.)

  8. The fabrication of front electrodes of Si solar cell by dispensing printing

    Highlights: ► We propose the process for the front silver electrode by employing dispensing method. ► The dispensing method is a non-contact printing process. ► The electrode by dispensing method has more uniform and narrower shape. ► The dispensing method helped to enhance the efficiency of solar cell by 0.8% absolute. - Abstract: The dispensing printing was applied to fabricate the front electrodes of silicon solar cell. In this method, a micro channel nozzle and normal Ag paste were employed. The aspect ratio and line width of electrodes could be controlled by the process variables such as the inner diameter of nozzle, dispensing speed, discharge pressure, and the gap between wafer and nozzle. For the nozzle with the inner diameter of 50 μm, the line width and aspect ratio of electrode were under 90 μm and more than ∼0.2, respectively. When comparing the efficiency of solar cell prepared by conventional screen printing and the dispensing printing, the latter exhibited 19.1%, which is 0.8% absolute higher than the former even with the same Ag paste. This is because the electrode by dispensing printing has uniform aspect ratio and narrow line width over the length of electrode.

  9. 30th International Acoustical Imaging Symposium

    Jones, Joie; Lee, Hua

    2011-01-01

    The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place every two years since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2009 the 30th International Symposium on Acoustical Imaging was held in Monterey, CA, USA, March 1-4. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 30 in the Series contains an excellent collection of forty three papers presented in five major categories: Biomedical Imaging Acoustic Microscopy Non-Destructive Evaluation Systems Analysis Signal Analysis and Image Processing Audience Researchers in medical imaging and biomedical instrumentation experts.

  10. Influence of container structures and content solutions on dispensing time of ophthalmic solutions

    Keiji Yoshikawa

    2010-05-01

    Full Text Available Keiji Yoshikawa1, Hiroshi Yamada21Yoshikawa Eye Clinic, Tokyo, Japan; 2Santen Pharmaceutical Co., Ltd., Osaka, JapanPurpose: To investigate the influence of container structures and content solutions on the time of dispensing from eye dropper bottles.Methods: Eye dropper bottle models, solution models (filtrate water/surfactant solution and a dispensing time measuring apparatus were prepared to measure the dispensing time.Results: With filtrate water and pressure thrust load of 0.3 MPa, the dispensing time significantly increased from 1.1 ± 0.5 seconds to 4.6 ± 1.1 seconds depending on the decrease of inner aperture diameters from 0.4 mm to 0.2 mm (P < 0.0001. When using the bottle models with inner aperture diameters of 0.4 mm or larger, the dispensing time became constant. The dispensing time using surfactant solution showed the same tendency as above. When pressure thrust load was large (0.07 MPa, the solution flew out continuously with inner aperture diameters of 0.4 mm or larger and the dispensing time could not be measured. The inner aperture diameter most strongly explained the variation of the dispensing time in both the content solutions in the multiple linear regression analysis (filtrate water: 46%, R2 = 0.462, surfactant solution: 56%, R2 = 0.563.Conclusions: Among content solutions and container structures, the dispensing time was mostly influenced by the diameter of the inner aperture of bottles.Keywords: dispensing time, model eye dropper bottle, model ophthalmic solution, nozzle internal space volume, nozzle inner aperture diameter

  11. Rational dispensing and use of artemether-lumefantrine during pregnancy in Dar es Salaam, Tanzania.

    Kamuhabwa, Appolinary R; Mnyusiwalla, Fatema

    2011-04-01

    Artemether-Lumefantrine (ALu) is widely used for uncomplicated malaria during the second and third trimester of pregnancy. Because of the suspected teratogenic effects of artemether during the first trimester, quinine is used in early pregnancy unless the risks outweigh the benefits. The aim of this study was to assess dispensing practice of ALu in private pharmacies and knowledge of pregnant women regarding the use of ALu. This was a prospective-descriptive study involving visits to 200 private retail pharmacies (using a mystery shopper) and interviewing pregnant women at the municipal public hospitals in Dar es Salaam, Tanzania. Among the drug dispensers, 60 (30%) were pharmacists, 71(35.5%) nurse assistants, 34 (17%) pharmaceutical technicians and 35 (17.5%) sales persons with no formal education on drug dispensing. Among the dispensers, 14.5% had high knowledge, 38.0% had medium knowledge and 47.5% had low knowledge on the use of ALu during pregnancy. About thirty three percent of the drug dispensers were willing to dispense ALu during the first trimester of pregnancy. Sixty two percent of the drug dispensers indicated that ALu is the drug of choice for uncomplicated malaria after the first trimester of pregnancy. However, 36% indicated that ALu could not be used during pregnancy. A total of 200 pregnant women were interviewed. Among them, 16.5% were aware that ALu should not be taken during the first trimester of pregnancy. Only 17% of pregnant women were given information on the importance of taking food when using ALu, but none of them was given information on the importance of fatty meals when using ALu. In conclusion, the results show that most drug dispensers have inadequate knowledge about good dispensing practice of ALu in pregnancy. There is therefore a need for continuing training of drug dispensers regarding antimalarial drugs use in pregnancy. PMID:25566607

  12. Acoustic Neurinomas

    Mohammad Faraji Rad

    2011-01-01

    Full Text Available Acoustic neuromas (AN are schwann cell-derived tumors that commonly arise from the vestibular portion of the eighth cranial nerve also known as vestibular schwannoma(VS causes unilateral hearing loss, tinnitus, vertigo and unsteadiness. In many cases, the tumor size may remain unchanged for many years following diagnosis, which is typically made by MRI. In the majority of cases the tumor is small, leaving the clinician and patient with the options of either serial scanning or active treatment by gamma knife radiosurgery (GKR or microneurosurgery. Despite the vast number of published treatment reports, comparative studies are few. The predominant clinical endpoints of AN treatment include tumor control, facial nerve function and hearing preservation. Less focus has been put on symptom relief and health-related quality of life (QOL. It is uncertain if treating a small tumor leaves the patient with a better chance of obtaining relief from future hearing loss, vertigo or tinnitus than by observing it without treatment.   In this paper we review the literature for the natural course, the treatment alternatives and the results of AN. Finally, we present our experience with a management strategy applied for more than 30 years.

  13. Acoustic Spatiality

    Brandon LaBelle

    2012-06-01

    Full Text Available Experiences of listening can be appreciated as intensely relational, bringing us into contact with surrounding events, bodies and things. Given that sound propagates and expands outwardly, as a set of oscillations from a particular source, listening carries with it a sensual intensity, whereby auditory phenomena deliver intrusive and disruptive as well as soothing and assuring experiences. The physicality characteristic of sound suggests a deeply impressionistic, locational "knowledge structure" – that is, the ways in which listening affords processes of exchange, of being in the world, and from which we extend ourselves. Sound, as physical energy reflecting and absorbing into the materiality around us, and even one's self, provides a rich platform for understanding place and emplacement. Sound is always already a trace of location.Such features of auditory experience give suggestion for what I may call an acoustical paradigm – how sound sets in motion not only the material world but also the flows of the imagination, lending to forces of signification and social structure, and figuring us in relation to each other. The relationality of sound brings us into a steady web of interferences, each of which announces the promise or problematic of being somewhere.

  14. Springer Handbook of Acoustics

    Rossing, Thomas D

    2007-01-01

    Acoustics, the science of sound, has developed into a broad interdisciplinary field encompassing the academic disciplines of physics, engineering, psychology, speech, audiology, music, architecture, physiology, neuroscience, and others. The Springer Handbook of Acoustics is an unparalleled modern handbook reflecting this richly interdisciplinary nature edited by one of the acknowledged masters in the field, Thomas Rossing. Researchers and students benefit from the comprehensive contents spanning: animal acoustics including infrasound and ultrasound, environmental noise control, music and human speech and singing, physiological and psychological acoustics, architectural acoustics, physical and engineering acoustics, signal processing, medical acoustics, and ocean acoustics. This handbook reviews the most important areas of acoustics, with emphasis on current research. The authors of the various chapters are all experts in their fields. Each chapter is richly illustrated with figures and tables. The latest rese...

  15. Responsive acoustic surfaces

    Peters, Brady; Tamke, Martin; Nielsen, Stig Anton;

    2011-01-01

    Acoustic performance is defined by the parameter of reverberation time; however, this does not capture the acoustic experience in some types of open plan spaces. As many working and learning activities now take place in open plan spaces, it is important to be able to understand and design for the...... acoustic conditions of these spaces. This paper describes an experimental research project that studied the design processes necessary to design for sound. A responsive acoustic surface was designed, fabricated and tested. This acoustic surface was designed to create specific sonic effects. The design was...... simulated using custom integrated acoustic software and also using Odeon acoustic analysis software. The research demonstrates a method for designing space- and sound-defining surfaces, defines the concept of acoustic subspace, and suggests some new parameters for defining acoustic subspaces....

  16. Acoustic Mechanical Feedthroughs

    Sherrit, Stewart; Walkemeyer, Phillip; Bao, Xiaoqi; Bar-Cohen, Yoseph; Badescu, Mircea

    2013-01-01

    Electromagnetic motors can have problems when operating in extreme environments. In addition, if one needs to do mechanical work outside a structure, electrical feedthroughs are required to transport the electric power to drive the motor. In this paper, we present designs for driving rotary and linear motors by pumping stress waves across a structure or barrier. We accomplish this by designing a piezoelectric actuator on one side of the structure and a resonance structure that is matched to the piezoelectric resonance of the actuator on the other side. Typically, piezoelectric motors can be designed with high torques and lower speeds without the need for gears. One can also use other actuation materials such as electrostrictive, or magnetostrictive materials in a benign environment and transmit the power in acoustic form as a stress wave and actuate mechanisms that are external to the benign environment. This technology removes the need to perforate a structure and allows work to be done directly on the other side of a structure without the use of electrical feedthroughs, which can weaken the structure, pipe, or vessel. Acoustic energy is pumped as a stress wave at a set frequency or range of frequencies to produce rotary or linear motion in a structure. This method of transferring useful mechanical work across solid barriers by pumping acoustic energy through a resonant structure features the ability to transfer work (rotary or linear motion) across pressure or thermal barriers, or in a sterile environment, without generating contaminants. Reflectors in the wall of barriers can be designed to enhance the efficiency of the energy/power transmission. The method features the ability to produce a bi-directional driving mechanism using higher-mode resonances. There are a variety of applications where the presence of a motor is complicated by thermal or chemical environments that would be hostile to the motor components and reduce life and, in some instances, not be

  17. The tungsten powder study of the dispenser cathode

    The intercorrelation of tungsten powder properties, such as grain size, distribution and morphology, and porous matrix parameters with electron emission capability and longevity of Ba dispenser cathodes has been investigated for the different grain morphologies. It is shown that a fully cleaning step of the tungsten powder is so necessary that the tungsten powder will be reduction of oxide in hydrogen atmosphere above 700 deg. C. The porosity of the tungsten matrix distributes more even and the closed pore is fewer, the average granule size of the tungsten powder distributes more convergent. The porosity of the tungsten matrix and the evaporation of the activator are bigger and the pulse of the cathode is smaller when the granularity is bigger by the analysis of the electronic microscope and diode experiment

  18. The tungsten powder study of the dispenser cathode

    Bao, Ji-xiu; Wan, Bao-fei

    2006-06-01

    The intercorrelation of tungsten powder properties, such as grain size, distribution and morphology, and porous matrix parameters with electron emission capability and longevity of Ba dispenser cathodes has been investigated for the different grain morphologies. It is shown that a fully cleaning step of the tungsten powder is so necessary that the tungsten powder will be reduction of oxide in hydrogen atmosphere above 700 °C. The porosity of the tungsten matrix distributes more even and the closed pore is fewer, the average granule size of the tungsten powder distributes more convergent. The porosity of the tungsten matrix and the evaporation of the activator are bigger and the pulse of the cathode is smaller when the granularity is bigger by the analysis of the electronic microscope and diode experiment.

  19. Organic electrospun nanofibers as vehicles toward intelligent pheromone dispensers: characterization by laboratory investigations.

    Lindner, I; Hein, D F; Breuer, M; Hummel, H E; Deuker, A; Vilcinskas, A; Leithold, G; Hellmann, C; Dersch, R; Wendorff, J H; Greiner, A

    2011-01-01

    Organic nanofibers have a history of technical application in various independent fields, including medical technology, filtration technology, and applications of pharmaceuticals via inhalation into the lungs. Very recently, in a joint effort with polymer chemists, agricultural applications have been added to this list of priorities. The aim is finding novel approaches to insect control. Pheromones, dispensed in a quantifiable way, are being used here in disrupting the mating communication between male and female pest insects, e.g. the European grapevine moth Lobesia botrana (Lepidoptera: Tortricidae), where current dispenser technology does not fully meet the high expectations of growers and environmentalists with respect to longevity of constant release, self decomposition, mechanical distribution, renewability as well as sustainability of resources. The methodology of electrospinning is exhaustively covered by Greiner and Wendorff (2007), with technical details reported by Hellmann et al. (2009), Hein et al. (2011), and Hummel et al. (2010). Wind tunnel studies were run within a tunnel with adjustable laminar flow and 0.5 m/sec air velocity. Mass losses of the electrospun fiber bundles were determined with a sensitive analytical balance 2-3 times per week and recorded as time vs. mass change. CLSA experiments were performed with a self developed glass apparatus (Lindner, 2010) based on various suggestions of previous authors. Microgram quantities of volatile pheromone (E,Z)-7,9-Dodecadienylacetate were absorbed on a filter of rigorously purified charcoal and desorbed by repeated micro extraction with a suitable solvent mixture. Aliquots of the solution were subjected to temperature programmed capillary GLC. Retention times were used for identification, whereas the area covered by the pheromone peak originating from a FID detector signal was integrated and compared with a carefully calibrated standard peak. Since these signals were usually in the low nanogram

  20. Sprayed, not stirred. A self-development of the company Sauter enables the dispension with agitators; Versprueht, nicht geruehrt. Eine Eigenentwicklung der Firma Sauter ermoeglicht es, auf Ruehrwerke zu verzichten

    Waid, Johanna

    2012-07-01

    'Simplicity is better' - This might be the motto of the company Sauter Biogas GmbH (Klipphausen, Federal Republic of Germany). The biogas plants of this company were developed from own practical experience and need any solids dispenser. A special mixing technology replaces the otherwise common agitators.

  1. A review of fishing technology by acoustic attraction%声诱捕捞技术的研究现状和应用前景

    张国胜; 杨超杰; 邢彬彬

    2012-01-01

    The concept and research status of fishing by acoustic attraction are introduced in world. Then the role of the fishing by acoustic attraction in protection of fishery resources and environment is considered based on present problems with fisheries. The application of the fishing by acoustic attraction is discussed and establishment of freshwater ranching fisheries is suggested in China.%介绍了声诱捕捞技术的概念及国内外声诱捕捞技术的研究现状;针对目前渔业资源所面临的问题,分析和探讨了声诱捕捞技术在保护渔业资源和渔业环境方面所起的作用;阐述了声诱捕捞技术的应用前景,并提出了结合声诱捕捞技术在中国建设淡水牧场的新构想.

  2. Acoustic source for generating an acoustic beam

    Vu, Cung Khac; Sinha, Dipen N.; Pantea, Cristian

    2016-05-31

    An acoustic source for generating an acoustic beam includes a housing; a plurality of spaced apart piezo-electric layers disposed within the housing; and a non-linear medium filling between the plurality of layers. Each of the plurality of piezoelectric layers is configured to generate an acoustic wave. The non-linear medium and the plurality of piezo-electric material layers have a matching impedance so as to enhance a transmission of the acoustic wave generated by each of plurality of layers through the remaining plurality of layers.

  3. Visualization of Surface Acoustic Waves in Thin Liquid Films.

    Rambach, R W; Taiber, J; Scheck, C M L; Meyer, C; Reboud, J; Cooper, J M; Franke, T

    2016-01-01

    We demonstrate that the propagation path of a surface acoustic wave (SAW), excited with an interdigitated transducer (IDT), can be visualized using a thin liquid film dispensed onto a lithium niobate (LiNbO3) substrate. The practical advantages of this visualization method are its rapid and simple implementation, with many potential applications including in characterising acoustic pumping within microfluidic channels. It also enables low-cost characterisation of IDT designs thereby allowing the determination of anisotropy and orientation of the piezoelectric substrate without the requirement for sophisticated and expensive equipment. Here, we show that the optical visibility of the sound path critically depends on the physical properties of the liquid film and identify heptane and methanol as most contrast rich solvents for visualization of SAW. We also provide a detailed theoretical description of this effect. PMID:26917490

  4. Visualization of Surface Acoustic Waves in Thin Liquid Films

    Rambach, R. W.; Taiber, J.; Scheck, C. M. L.; Meyer, C.; Reboud, J.; Cooper, J. M.; Franke, T.

    2016-01-01

    We demonstrate that the propagation path of a surface acoustic wave (SAW), excited with an interdigitated transducer (IDT), can be visualized using a thin liquid film dispensed onto a lithium niobate (LiNbO3) substrate. The practical advantages of this visualization method are its rapid and simple implementation, with many potential applications including in characterising acoustic pumping within microfluidic channels. It also enables low-cost characterisation of IDT designs thereby allowing the determination of anisotropy and orientation of the piezoelectric substrate without the requirement for sophisticated and expensive equipment. Here, we show that the optical visibility of the sound path critically depends on the physical properties of the liquid film and identify heptane and methanol as most contrast rich solvents for visualization of SAW. We also provide a detailed theoretical description of this effect. PMID:26917490

  5. Reductions in finger doses for radiopharmaceutical dispensing afforded by a syringe shield and an automatic dose dispenser

    The Gamma Extremity Monitoring System (GEMS) uses a small semiconductor probe from which a continuous readout of dose-rate is obtained (Montgomery et al, 1997). It-is a small, lightweight system that is simple to use and can provide rapid feedback. With GEMS doses received from individual operations and actions within a particular procedure can be recorded so that the pattern of dose accumulation can be analysed enabling techniques to be optimised for dose reduction, the whole process taking a relatively short period of time. The present study reports how a GEMS has been utilised to compare the radiation dose reduction afforded by a syringe and an automatic dose dispenser and looks at the pattern of dose accumulation during each procedure. (Author)

  6. Evaluation of a new photoresist dispense system to detect coating variation

    Gapin, Florent; Le-Peutrec, Bernard; Stock, Laurent; Hanotte, Marc

    2009-03-01

    A minimal change of dispensed volume will have a severe impact on the film thickness uniformity and in the worst case there might be some lack of resist on the wafer. Therefore it is essential to set-up the photoresist dispense accurately to avoid any dispense variation. In addition, it is important to monitor the dispense conditions real-time to detect problems which may have a direct negative impact on process yield. This paper presents the evaluation of the IntelliGen® Mini dispense system which is manufactured by Entegris, Inc. This new system is able to detect variations like bubbles in the dispense line, changes to the stop suckback valve, and changes in viscosity1. After an explanation of the pump characteristics and the potential root causes of dispense variation and their consequences, the evaluation done in Altis Semiconductor will be presented. The study has been made utilizing different photo-chemicals, including low and mid-range viscosity photo- resists and anti-reflective coatings. The capability of this new product to detect any perturbation of coating will be demonstrated. Then standard tests like coating repeatability, defect density CD uniformity and finally wafer yield inspection will be performed to prove efficiency of the system in a production mode.

  7. The accuracy and timeliness of neuraminidase inhibitor dispensing data for predicting laboratory-confirmed influenza.

    Papenburg, J; Charland, K M; DE Serres, G; Buckeridge, D L

    2016-06-01

    Neuraminidase inhibitor (NI) dispensing has emerged as a possible automated data source for influenza surveillance. We aimed to evaluate its timeliness, correlation, and predictive accuracy in relation to influenza activity in Quebec, Canada, 2010-2013. Our secondary objective was to use the same metrics to compare NI dispensing to visits for influenza-like illness (ILI) in emergency departments (EDs). Provincial weekly counts of positive influenza laboratory tests were used as a reference measure for the level of influenza circulation. We applied ARIMA models to account for serial correlation. We computed cross-correlations to measure the strengths of association and lead-lag relationships between NI dispensing, ILI ED visits, and our reference indicator. Finally, using an ARIMA model, we evaluated the ability of NI dispensing and ILI ED visits to predict laboratory-confirmed influenza. NI dispensing was significantly correlated (R = 0·68) with influenza activity with no lag. The maximal correlation of ILI ED visits was not as strong (R = 0·50). Both NI dispensing and ILI ED visits were significant predictors of laboratory-confirmed influenza in a multivariable model; predictive potential was greatest when NI counts were lagged to precede laboratory surveillance by 2 weeks. We conclude that NI dispensing data provides timely and valuable information for influenza surveillance. PMID:26611607

  8. Impact of educational intervention on knowledge of dispensers working at community pharmacies in Pakistan

    Hussain A

    2013-09-01

    Full Text Available Objective: To evaluate the impact of training of dispensers on knowledge of dispensers working at community pharmacies in context to storage temperature, prescription terminologies and status of medicines in Islamabad, Pakistan.Method: A randomized, controlled, blinded intervention study was designed and implemented. Before the implementation of intervention, a baseline study was performed to assess the knowledge of dispensers working at community pharmacies. The study population included all community pharmacy outlets in Islamabad. Pharmacies of Islamabad which were visited in pre intervention phase (n=118 were divided into two geographical regions: A (intervention and B (control. Thirty pharmacies were randomly selected from each region. Keeping in view the results of the baseline study an educational intervention was designed to improve the knowledge of dispensers working at community pharmacies in Pakistan.Results: A significant difference in the overall knowledge of dispensers was observed between the pre-post intervention groups. Knowledge of dispensers regarding storage of drugs, prescription terminologies and status of drugs was improved after the training. On the other hand no significant difference was observed between the pre-post control groups.Conclusion: The study has highlighted that improvements in knowledge of dispensers working at community pharmacies are possible through suitable interventions. But, results of interventions can only be sustainable through continuous monitoring and reinforcement of the training.

  9. High-Precision Dispensing of Nanoliter Biofluids on Glass Pedestal Arrays for Ultrasensitive Biomolecule Detection.

    Chen, Xiaoxiao; Liu, Yang; Xu, QianFeng; Zhu, Jing; Poget, Sébastien F; Lyons, Alan M

    2016-05-01

    Precise dispensing of nanoliter droplets is necessary for the development of sensitive and accurate assays, especially when the availability of the source solution is limited. Conventional approaches are limited by imprecise positioning, large shear forces, surface tension effects, and high costs. To address the need for precise and economical dispensing of nanoliter volumes, we developed a new approach where the dispensed volume is dependent on the size and shape of defined surface features, thus freeing the dispensing process from pumps and fine-gauge needles requiring accurate positioning. The surface we fabricated, called a nanoliter droplet virtual well microplate (nVWP), achieves high-precision dispensing (better than ±0.5 nL or ±1.6% at 32 nL) of 20-40 nL droplets using a small source drop (3-10 μL) on isolated hydrophilic glass pedestals (500 μm on a side) bonded to arrays of polydimethylsiloxane conical posts. The sharp 90° edge of the glass pedestal pins the solid-liquid-vapor triple contact line (TCL), averting the wetting of the glass sidewalls while the fluid is prevented from receding from the edge. This edge creates a sufficiently large energy barrier such that microliter water droplets can be poised on the glass pedestals, exhibiting contact angles greater >150°. This approach relieves the stringent mechanical alignment tolerances required for conventional dispensing techniques, shifting the control of dispensed volume to the area circumscribed by the glass edge. The effects of glass surface chemistry and dispense velocity on droplet volume were studied using optical microscopy and high-speed video. Functionalization of the glass pedestal surface enabled the selective adsorption of specific peptides and proteins from synthetic and natural biomolecule mixtures, such as venom. We further demonstrate how the nVWP dispensing platform can be used for a variety of assays, including sensitive detection of proteins and peptides by fluorescence

  10. Acoustic Neuroma Educational Video

    Full Text Available ... Watch and Wait Radiation Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask Yourself ... Watch and Wait Radiation Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask Yourself ...

  11. Acoustic Neuroma Educational Video

    Full Text Available ... is ANA? Mission Statement Board of Directors ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic ... is ANA? Mission Statement Board of Directors ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic ...

  12. Acoustic Neuroma Educational Video

    Full Text Available ... ANA Annual Reports Acoustic Neuroma Legacy Society Programs & Services Join/Renew Ways to Give ANA Discussion Forum ... ANA Annual Reports Acoustic Neuroma Legacy Society Programs & Services Search ANAUSA.org Connect with us! Educational Video ...

  13. Acoustic Neuroma Educational Video

    Full Text Available ... Resources Patient Surveys Related Links Clinical Trials.gov Health Care Insurance Toolkit Additional Resources ANA Public Webinars © 2016 Acoustic Neuroma Association Acoustic Neuroma Association ® • ...

  14. Acoustic Neuroma Educational Video

    Full Text Available ... Options Watch and Wait Radiation Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask ... Options Watch and Wait Radiation Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask ...

  15. Acoustic Neuroma Educational Video

    Full Text Available ... ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic Neuroma Legacy Society Programs & Services Join/Renew ... ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic Neuroma Legacy Society Programs & Services Search ANAUSA. ...

  16. Cystic acoustic neuromas

    Chitkara, Naveen; Chanda, Rakesh; Yadav, S. P. S.; N.K. Sharma

    2002-01-01

    Predominantly cystic acoustic neuromas are rare and they usually present with clinical and radiological features different from their more common solid counterparts. Two cases of cystic acoustic neuromas are reported here.

  17. 基于声学参量阵的次声波定向仿真技术研究%Research on the Infrasound Directed Simulation Technology Based on Acoustic Parametric Arrays

    张娜; 乔卫东

    2012-01-01

    The paper focus on the generation and orientation of the infrasound wave. By using the DDS technology, the different frequencies of Infrasoundwave is generated through the electro-acoustic conver-sion method. The orientation of infrasound wave has been formed by the way of acoustic parametric arrays which take the advantage of two ultrasound superposition and modulation. The sidelobe can be effectively suppressd and the infrasound wave can be centralized in the axial direction by the method so that trans-mission and orientation of the infrasound wave can be resolved. The feasibility of this method can be veri-fied by the simulation experiment.%针对次声波生成及定向技术展开研究.采用DDS技术通过电声转换实现了不同频率次声波的生成;应用声学参量阵,以两路超声波通过叠加,实现以超声波载波调制生成次生波.该方法可有效抑制旁瓣,使次声波主要集中在主轴方向,解决了次声波的定向传播问题,并通过仿真实验验证了该方法的可行性.

  18. Parenteral medication prescriptions, dispensing and administration habits in Mongolia.

    Gereltuya Dorj

    Full Text Available High levels of injection prescribing were reported in Mongolia. Understanding the factors influencing the injection prescribing is essential to reduce their inappropriate use. The study evaluated the views, experiences and attitudes of community members associated with the prescribing of injections in Mongolia. A structured questionnaire focusing on respondents' characteristics, experiences and views about injections was developed and administered face-to-face to community members in Ulaanbaatar, Mongolia. Standard descriptive statistics were used to summarize demographic data and responses to the questionnaires. Dependent variables were compared using Kruskal-Wallis Tests for independence. Statistical analyses were performed using SPSS Version 21.0. Six hundred participants were approached and the response rate was 79% (n = 474. Almost half of the respondents were aged between 31 and 50 (n = 228, 48.1% and 40.9% of respondents were male (n = 194. Most respondents were from Ulaanbaatar city (n = 407, 85.7%. All respondents had received injections in the past and 268 (56.5% had received injection in the past year. The most common reason for having an injection in the past year was reported as treatment of a disease (n = 163, 60.8%, or for administration of vitamins (n = 70, 26.1%. Injections were prescribed by a doctor (n = 353, 74.9%, dispensed by a pharmacist (n = 283, 59.7% and administered by a nurse (n = 277, 54.9%. Only 16% of all respondents had the expectation of receiving injections when they visited a doctor (n = 77. An important perception regarding injections was that they hastened the recovery process (n = 269, 56.8%. When asked their opinion about therapeutic injections, 40% of all respondents agreed that injections were a better medicine (n = 190 than oral medications, with older respondents strongly agreeing (p<0.001. Based on this total sample, approximately 1891 injections per 1000 patients were administered. The excessive

  19. Towards more reliable automated multi-dose dispensing: retrospective follow-up study on medication dose errors and product defects.

    Palttala, Iida; Heinämäki, Jyrki; Honkanen, Outi; Suominen, Risto; Antikainen, Osmo; Hirvonen, Jouni; Yliruusi, Jouko

    2013-03-01

    To date, little is known on applicability of different types of pharmaceutical dosage forms in an automated high-speed multi-dose dispensing process. The purpose of the present study was to identify and further investigate various process-induced and/or product-related limitations associated with multi-dose dispensing process. The rates of product defects and dose dispensing errors in automated multi-dose dispensing were retrospectively investigated during a 6-months follow-up period. The study was based on the analysis of process data of totally nine automated high-speed multi-dose dispensing systems. Special attention was paid to the dependence of multi-dose dispensing errors/product defects and pharmaceutical tablet properties (such as shape, dimensions, weight, scored lines, coatings, etc.) to profile the most suitable forms of tablets for automated dose dispensing systems. The relationship between the risk of errors in dose dispensing and tablet characteristics were visualized by creating a principal component analysis (PCA) model for the outcome of dispensed tablets. The two most common process-induced failures identified in the multi-dose dispensing are predisposal of tablet defects and unexpected product transitions in the medication cassette (dose dispensing error). The tablet defects are product-dependent failures, while the tablet transitions are dependent on automated multi-dose dispensing systems used. The occurrence of tablet defects is approximately twice as common as tablet transitions. Optimal tablet preparation for the high-speed multi-dose dispensing would be a round-shaped, relatively small/middle-sized, film-coated tablet without any scored line. Commercial tablet products can be profiled and classified based on their suitability to a high-speed multi-dose dispensing process. PMID:22458299

  20. APPLICATION OF THE INSTANT HOT WATER DISPENSER INTEGRATED INTO THE INTERNAL WATER SUPPLY SYSTEM OF RESIDENTIAL BUILDINGSAS AMETHOD OF SAVING POWER AND OTHER RESOURCES

    Orlov Evgeniy Vladimirovich

    2012-01-01

    The author compares the instant water boiling technology and the use of electric teapots in the article. Strengths and weaknesses of the instant water boiling technology and its integration into the internal water supply system are also demonstrated. Aqua Hot 98 instant hot water dispenser is capable of heating up to 60 cups in an hour, while consuming 20 % of the electric power needed to boil the water on a stove or in an electric tea pot. Besides, the water is ready for consumption at a...

  1. A simple low-cost of liquid I-131 dispenser for routine radiopharmaceutical dispensing at nuclear medicine department, Institut Kanser Negara

    In routine radiopharmaceutical Iodine-131 (131I) dispensing, the amount of radiation dose received by the personnel depends on the distance between the personnel and the source, the time spent manipulating the source and the amount of shielding used to reduce the dose rate from the source. The novel iRAD-I131 dispenser using recycle 131I liquid lead pot will lead into low cost production, less maintenance and low dose received by the personnel that prepared the 131I. The new fabricated of low cost 131I dispenser was tested and the dose received by personnel were evaluated. The body of lead material is made from 2.5 cm lead shielded coated with epoxy paint to absorb the radiation dose up to 7.4 GBq of 131 I. The lead pot was supported with two stainless steel rod. The Optically Stimulated Luminescence (OSL) nanodot was used in this study to measure the dose rate at both extremities for every personnel who prepared the 131I. Each OSL nanodot was attached at the fingertip. Three different personnel (experienced between one to ten years above in preparing the radiopharmaceuticals) were participated in this study. The average equivalent dose at right and left hand were 122.694 ± 121.637 µSv/GBq and 77.281 ± 62.146 µSv/GBq respectively. This study found that the dose exposure received using iRAD-I131 was less up to seven times compared to the conventional method. The comparison of experimental data using iRAD-I131 and established radiopharmaceutical dispenser was also discussed. The innovation of 131I dispenser is highly recommended in a small radiopharmaceutical facility with limited budget. The novel iRAD-I131 enables implementation of higher output liquid dispensing with low radiation dose to the personnel

  2. A simple low-cost of liquid I-131 dispenser for routine radiopharmaceutical dispensing at nuclear medicine department, Institut Kanser Negara

    Said, M. A.; Suhaimi, N. E. F. [Fakulti Sains dan Teknologi, Universiti Kebangsaan Malaysia, 43600 UKM, Bangi Selangor (Malaysia); Ashhar, Z. N., E-mail: aminhpj@gmail.com [Institut Kanser Negara, No 4, Jalan P7, Presint 7, 62250 Putrajaya (Malaysia); Zainon, R. [Advanced Medical & Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang (Malaysia)

    2016-01-22

    In routine radiopharmaceutical Iodine-131 ({sup 131}I) dispensing, the amount of radiation dose received by the personnel depends on the distance between the personnel and the source, the time spent manipulating the source and the amount of shielding used to reduce the dose rate from the source. The novel iRAD-I131 dispenser using recycle {sup 131}I liquid lead pot will lead into low cost production, less maintenance and low dose received by the personnel that prepared the {sup 131}I. The new fabricated of low cost {sup 131}I dispenser was tested and the dose received by personnel were evaluated. The body of lead material is made from 2.5 cm lead shielded coated with epoxy paint to absorb the radiation dose up to 7.4 GBq of {sup 131} I. The lead pot was supported with two stainless steel rod. The Optically Stimulated Luminescence (OSL) nanodot was used in this study to measure the dose rate at both extremities for every personnel who prepared the {sup 131}I. Each OSL nanodot was attached at the fingertip. Three different personnel (experienced between one to ten years above in preparing the radiopharmaceuticals) were participated in this study. The average equivalent dose at right and left hand were 122.694 ± 121.637 µSv/GBq and 77.281 ± 62.146 µSv/GBq respectively. This study found that the dose exposure received using iRAD-I131 was less up to seven times compared to the conventional method. The comparison of experimental data using iRAD-I131 and established radiopharmaceutical dispenser was also discussed. The innovation of {sup 131}I dispenser is highly recommended in a small radiopharmaceutical facility with limited budget. The novel iRAD-I131 enables implementation of higher output liquid dispensing with low radiation dose to the personnel.

  3. A simple low-cost of liquid I-131 dispenser for routine radiopharmaceutical dispensing at nuclear medicine department, Institut Kanser Negara

    Said, M. A.; Ashhar, Z. N.; Suhaimi, N. E. F.; Zainon, R.

    2016-01-01

    In routine radiopharmaceutical Iodine-131 (131I) dispensing, the amount of radiation dose received by the personnel depends on the distance between the personnel and the source, the time spent manipulating the source and the amount of shielding used to reduce the dose rate from the source. The novel iRAD-I131 dispenser using recycle 131I liquid lead pot will lead into low cost production, less maintenance and low dose received by the personnel that prepared the 131I. The new fabricated of low cost 131I dispenser was tested and the dose received by personnel were evaluated. The body of lead material is made from 2.5 cm lead shielded coated with epoxy paint to absorb the radiation dose up to 7.4 GBq of 131 I. The lead pot was supported with two stainless steel rod. The Optically Stimulated Luminescence (OSL) nanodot was used in this study to measure the dose rate at both extremities for every personnel who prepared the 131I. Each OSL nanodot was attached at the fingertip. Three different personnel (experienced between one to ten years above in preparing the radiopharmaceuticals) were participated in this study. The average equivalent dose at right and left hand were 122.694 ± 121.637 µSv/GBq and 77.281 ± 62.146 µSv/GBq respectively. This study found that the dose exposure received using iRAD-I131 was less up to seven times compared to the conventional method. The comparison of experimental data using iRAD-I131 and established radiopharmaceutical dispenser was also discussed. The innovation of 131I dispenser is highly recommended in a small radiopharmaceutical facility with limited budget. The novel iRAD-I131 enables implementation of higher output liquid dispensing with low radiation dose to the personnel.

  4. 21 CFR 866.2440 - Automated medium dispensing and stacking device.

    2010-04-01

    ... stacking device is a device intended for medical purposes to dispense a microbiological culture medium into... practice requirements of the quality system regulation in part 820 of this chapter, with the exception...

  5. Separation of prescribing and dispensing in Malaysia: a summary of arguments.

    Shafie, Asrul Akmal; Hassali, Mohamed Azmi; Azhar, Saira; See, Ooi Guat

    2012-01-01

    The role of pharmacists has transformed significantly because of changes in pharmacists' training and population health demands. Within this context, community pharmacists are recognized as important health personnel for the provision of extended health services. Similarly, in Malaysia, the need to transform community pharmacy practice has been discussed by all interested parties; however, the transition has been slow due in part to the nonexistence of a dispensing separation policy between pharmacists and medical doctors in private community practices. For decades, medical doctors in private community practices have had the right to prescribe and dispense, thus diluting the role of community pharmacists because of overlapping roles. This article explores dispensing separation in Malaysia and, by taking into account the needs of health professionals and health care consumers, suggests a mechanism for how dispensing separation practice can be implemented. PMID:21824823

  6. Investigation of the adsorption of the evaporation products from the dispensed emitters on the scandium oxide

    It is shown that at simultaneous sputtering on the scandium oxide of the evaporation products from the surface of the dispensed emitters such as barium, barium oxide and calcium, the adsorption has a complicated nature.

  7. ACOUSTICAL STANDARDS NEWS.

    Blaeser, Susan B; Struck, Christopher J

    2016-03-01

    American National Standards (ANSI Standards) developed by Accredited Standards Committees S1, S2, S3, S3/SC 1, and S12 in the areas of acoustics, mechanical vibration and shock, bioacoustics, animal bioacoustics, and noise, respectively, are published by the Acoustical Society of America (ASA). In addition to these standards, ASA publishes a catalog of Acoustical American National Standards. To receive a copy of the latest Standards catalog, please contact Susan B. Blaeser.Comments are welcomed on all material in Acoustical Standards News.This Acoustical Standards News section in JASA, as well as the National Catalog of Acoustical Standards and other information on the Standards Program of the Acoustical Society of America, are available via the ASA home page: http://acousticalsociety.org. PMID:27036268

  8. Balance Transmission Mechanism in Underwater Acoustic Sensor Networks

    Jiabao Cao; Jinfeng Dou; Shunle Dong

    2015-01-01

    With the rapid development of underwater acoustic modem technology, underwater acoustic sensor networks (UWASNs) have more applications in long-term monitoring of the deployment area. In the underwater environment, the sensors are costly with limited energy. And acoustic communication medium poses new challenges, including high path loss, low bandwidth, and high energy consumption. Therefore, designing transmission mechanism to decrease energy consumption and to optimize the lifetime of UWASN...

  9. Continued Dispensing: what medications do patients believe should be available?

    Salem Hasn Abukres

    2015-05-01

    Full Text Available Background. Continued Dispensing (CD is a new medication supply method for certain medications in Australia. It aims to prevent treatment interruption as a result of patients’ inability to obtain a new valid prescription. The only currently eligible patients for this service are statin and/or oral contraceptives users who have been using these medications for 6 months or more, have not utilized the CD method during the last 12 months, and cannot obtain an immediate appointment with the prescriber in order to get a new prescription. This study aimed to investigate patients’ attitudes towards potential extension and expansion of this medication supply method. Methods. A randomly selected 301 users of these medications from all Australian States were recruited using Computer Assisted Telephone Interview (CATI. Result. The response rate was 79%. The majority of the participants (73.3% did not agree with current restriction on CD utilization frequency. They also supported, to varying degrees, inclusion of all the proposed medications (support ranged from 44.2–78.4%. In this regard, participants who suffered from a specific disease did not differ significantly from those without the disease except in case of patients with depression (p = 0.001. Conclusions. Participants of this study strongly supported both CD extension and expansion. A future critical review of the current version of CD is highly recommended in order to enhance CD capability to achieve its goals.

  10. Continued Dispensing: what medications do patients believe should be available?

    Abukres, Salem Hasn; Hoti, Kreshnik; Hughes, Jeffery David

    2015-01-01

    Background. Continued Dispensing (CD) is a new medication supply method for certain medications in Australia. It aims to prevent treatment interruption as a result of patients' inability to obtain a new valid prescription. The only currently eligible patients for this service are statin and/or oral contraceptives users who have been using these medications for 6 months or more, have not utilized the CD method during the last 12 months, and cannot obtain an immediate appointment with the prescriber in order to get a new prescription. This study aimed to investigate patients' attitudes towards potential extension and expansion of this medication supply method. Methods. A randomly selected 301 users of these medications from all Australian States were recruited using Computer Assisted Telephone Interview (CATI). Result. The response rate was 79%. The majority of the participants (73.3%) did not agree with current restriction on CD utilization frequency. They also supported, to varying degrees, inclusion of all the proposed medications (support ranged from 44.2-78.4%). In this regard, participants who suffered from a specific disease did not differ significantly from those without the disease except in case of patients with depression (p = 0.001). Conclusions. Participants of this study strongly supported both CD extension and expansion. A future critical review of the current version of CD is highly recommended in order to enhance CD capability to achieve its goals. PMID:26019994

  11. Dynamic behavior of thermionic dispenser cathodes under ion bombardment

    Cortenraad, R.; van der Gon, A. W. Denier; Brongersma, H. H.; Gärtner, G.; Raasch, D.; Manenschijn, A.

    2001-04-01

    We have investigated the surface coverage and electron emission of thermionic dispenser cathodes during 3 keV Ar+ ion bombardment, thereby simulating the bombardment of the cathodes by residual gases that takes place in cathode-ray tubes as used in television sets. During the ion bombardment at the operating temperature of 1030 °C, a dynamic equilibrium is established between the sputter removal and resupply mechanisms of the Ba and O atoms that form the dipole layer on the cathode substrate. We demonstrated that the performance of the cathodes under ion bombardment is governed by the O removal and resupply rates. It was found that the Ba resupply rate is almost an order of magnitude higher than the O resupply rate, but that the Ba can only be present on the surface bound to O atoms. Therefore, the Ba/O ratio is approximately equal to unity during the ion bombardment. Based on the investigations of the removal and resupply processes, we proposed a model that accurately describes the surface coverage and electron emission during the ion bombardment, including the dependence of the ion flux and cathode temperature.

  12. Piwi genes are dispensable for normal hematopoiesis in mice.

    Nolde, Mona J; Cheng, Ee-Chun; Guo, Shangqin; Lin, Haifan

    2013-01-01

    Hematopoietic stem cells (HSC) must engage in a life-long balance between self-renewal and differentiation to sustain hematopoiesis. The highly conserved PIWI protein family regulates proliferative states of stem cells and their progeny in diverse organisms. A Human piwi gene (for clarity, the non-italicized "piwi" refers to the gene subfamily), HIWI (PIWIL1), is expressed in CD34⁺ stem/progenitor cells and transient expression of HIWI in a human leukemia cell line drastically reduces cell proliferation, implying the potential function of these proteins in hematopoiesis. Here, we report that one of the three piwi genes in mice, Miwi2 (Piwil4), is expressed in primitive hematopoetic cell types within the bone marrow. Mice with a global deletion of all three piwi genes, Miwi, Mili, and Miwi2, are able to maintain long-term hematopoiesis with no observable effect on the homeostatic HSC compartment in adult mice. The PIWI-deficient hematopoetic cells are capable of normal lineage reconstitution after competitive transplantation. We further show that the three piwi genes are dispensable during hematopoietic recovery after myeloablative stress by 5-FU. Collectively, our data suggest that the function of the piwi gene subfamily is not required for normal adult hematopoiesis. PMID:24058407

  13. Superoxide dismutase is dispensable for normal animal lifespan.

    Van Raamsdonk, Jeremy Michael; Hekimi, Siegfried

    2012-04-10

    Reactive oxygen species (ROS) are toxic oxygen-containing molecules that can damage multiple components of the cell and have been proposed to be the primary cause of aging. The antioxidant enzyme superoxide dismutase (SOD) is the only eukaryotic enzyme capable of detoxifying superoxide, one type of ROS. The fact that SOD is present in all aerobic organisms raises the question as to whether SOD is absolutely required for animal life and whether the loss of SOD activity will result in decreased lifespan. Here we use the genetic model organism Caenorhabditis elegans to generate an animal that completely lacks SOD activity (sod-12345 worms). We show that sod-12345 worms are viable and exhibit a normal lifespan, despite markedly increased sensitivity to multiple stresses. This is in stark contrast to what is observed in other genetic model organisms where the loss of a single sod gene can result in severely decreased survival. Investigating the mechanism underlying the normal lifespan of sod-12345 worms reveals that their longevity results from a balance between the prosurvival signaling and the toxicity of superoxide. Overall, our results demonstrate that SOD activity is dispensable for normal animal lifespan but is required to survive acute stresses. Moreover, our findings indicate that maintaining normal stress resistance is not crucial to the rate of aging. PMID:22451939

  14. Simulation of Filament Heater for Uniform Emission from Dispenser Cathode

    Singh, Narendra Kr.; Bhattacharya, Ranojoy; Khatun, Hasina; Singh, Udaybir; Sinha, A. K.

    2012-06-01

    This paper presents the design study of toroid shape filament heater for dispenser cathode.The filament heater will be used in cathode assembly of 200 kW 42 GHz gyrotron. A 3 D model of cathode assembly is designed using electromagnetic and thermal simulation software, ANSYS. The simulations are performed for optimizing the input filament heater power with respect to cathode surface temperature. The parametric study shows that the input power and cathode surface temperature depends strongly on the potting material, diameter of filament, number of turns, position and height of the filament heater with respect to cathode pellet. The design analyses are also carried out for two different filament heater materials i.e. tungsten and molybdenum. Further, the thermal, structural and transient analyses are also carried out to study the mechanical strength of the filament heater. It is concluded that the input heater power should be greater than 200 W to achieve cathode surface temperature greater than 1,000°C.

  15. Patterning of dispenser cathode surfaces to a controlled porosity

    Garner, Charles E.; Deininger, William D.; Gibson, John; Thomas, Richard

    1989-01-01

    A process to pattern slots approximately 1.25 microns in width into 25-micron-thick W films that have been deposited onto flat or concave surfaces is discussed. A 25-micron-thick W film with a high degree of (100) orientation is chemically vapor deposited (CVD) onto a flat or concave Mo mandrel. A 5-micron-thick Al film is deposited onto the CVD W, followed by 2 microns of photoresist. On concave cathodes, XeCl2 laser ablation or X-ray lithography is used to pattern the photoresist, whereas on flat cathodes deep UV lithography can be used. The patterned photoresist serves as the mask in a Cl ion-beam-assisted etching (IBAE) process to pattern the Al. An alternative process is to deposit Al2O3 films onto the W and pattern the Al2O3 using laser ablation. The W film is then patterned to 3-6-micron slot widths using IBAE + ClF3 with the patterned Al or Al2O3 as the mask. Finally, a sputter deposition step is required to close up the slots to approximately 1 micron. The process described is capable of patterning concave dispenser cathodes to a controlled and precise porosity.

  16. Sterility testing of a dispensing valve for aseptic function in food service applications.

    Stopforth, J D; Kottapalli, B; Samadpour, M

    2008-03-01

    Manual dispensing equipment for aseptically packaged beverages or foods requires refrigeration of the product package following breakage of the hermetic seal. The food service industry would benefit greatly by implementing dispensing equipment that maintains the sterility of products after continued use without the need for refrigeration. The purpose of this study was to evaluate the ability of a valve, designed to operate aseptically and dispense products with or without refrigeration, to maintain the sterility of products following breakage of the hermetic seal and continued use simulating that of food service. Plastic packages equipped with the "aseptic" dispensing valve in a bag-in-box (BIB) format were aseptically filled with enrichment media with and without the addition of 1% cornstarch to simulate high- and low-viscosity products, respectively. BIBs filled with media were left uninoculated or inoculated (10(4) CFU/ml) with Staphylococcus aureus or Aspergillus niger on the interior of the spout 1 cm from the opening to simulate consumer misuse. Uninoculated and inoculated BIBs were stored at 25 degrees C, and media were dispensed once to twice per day, every day for up to 30 days to simulate food service use. Dispensates were observed for turbidity (compared with controls) indicating growth in BIBs and, thus, breach of sterility. Growth of samples taken aseptically through the package wall was checked microbiologically every 5 days by standard plating techniques. There was no breach in sterility until day 25. At day 25, uninoculated BIB (1 of 45 samples positive for growth) containing high-viscosity media and BIB inoculated with S. aureus (1 of 45 samples positive for growth) containing low-viscosity media became turbid. Viscosity and type of organism did not appear to influence the ability of the valve to maintain the sterility for > or =20 days. The results of this study provide evidence that the dispensing valve tested can maintain the sterility of

  17. Implementation of Multidose Drug Dispensing in a Home Care Setting: Changes in Safety of Medicines Management

    Wekre, Liv Johanne

    2014-01-01

    Multidose dispensed drugs are drugs machine-packed into dose unit bags for each time of administration. Trondheim municipality decided in 2005 to implement Multidose Drug Dispensing (MDD) in home care services. At that time, there was a lack of scientific knowledge about the effects of MDD. The health care management of Trondheim therefore decided to study the implementation in collaboration with NTNU. MDD was adopted gradually during 2006.Three studies were conducted with the common main aim...

  18. Recommendations and requirements for soap and hand rub dispensers in healthcare facilities

    Assadian, O.; Kramer, A.; Christiansen, B.; Exner, M; Martiny, H; Sorger, A; Suchomel, M; Section Clinical Antisepsis of the German Society for Hospital Hygiene (DGKH); Disinfection Assessment Board of the Austrian Society for Hygiene, Microbiology and Preventive Medicine (ÖGHMP)

    2012-01-01

    Hand hygiene is one of the most important measures to prevent transmission of infectious agents and plays a major role in prevention of infection in any type of healthcare setting. While requirements for the efficacy of hand disinfectants are defined in European testing norms such as the EN 1500 for hygienic hand disinfection or EN 12791 for surgical hand preparation, no specific recommendations for hand rub dispensers and liquid soap dispensers have been given yet. Therefore, the intention o...

  19. Multilayer Integrated Film Bulk Acoustic Resonators

    Zhang, Yafei

    2013-01-01

    Multilayer Integrated Film Bulk Acoustic Resonators mainly introduces the theory, design, fabrication technology and application of a recently developed new type of device, multilayer integrated film bulk acoustic resonators, at the micro and nano scale involving microelectronic devices, integrated circuits, optical devices, sensors and actuators, acoustic resonators, micro-nano manufacturing, multilayer integration, device theory and design principles, etc. These devices can work at very high frequencies by using the newly developed theory, design, and fabrication technology of nano and micro devices. Readers in fields of IC, electronic devices, sensors, materials, and films etc. will benefit from this book by learning the detailed fundamentals and potential applications of these advanced devices. Prof. Yafei Zhang is the director of the Ministry of Education’s Key Laboratory for Thin Films and Microfabrication Technology, PRC; Dr. Da Chen was a PhD student in Prof. Yafei Zhang’s research group.

  20. Impact of Robotic Dispensing Machines in German Pharmacies on Business Performance Indicators

    Ruhle F

    2009-01-01

    Full Text Available Aims and objectives: To assess the impact of robotic dispensing machines in community pharmacies on staff efficiency and sales of over-the-counter drugs. Setting: The study was done on 253 community pharmacies in Germany that use a robotic dispensing machine manufactured by ROWA during 2008. Method: Data concerning the financial and economic impact of using a robotic dispensing machine in community pharmacies was gathered using a structured questionnaire and analysed in terms of its financial implications. Key findings: The response rate was 29%. In most pharmacies (79% the robotic dispensing machine was retrofitted. In 59% of the pharmacies additional space was gained for self-service and behind-the-counter display. As a result of using a robotic dispensing machine, personnel costs were reduced by an average of 4.6% during the first 12 months after start-up. Over-the-counter sales increased in the same period by an average of 6.8%. Despite average initial costs of 118,000 euros, total costs within the first 12 months fell in 50% of cases and at least remained the same in 44%. Conclusions: On average, robotic dispensing machines lead to modest savings in personnel costs and slight increases in sales of over-the-counter drugs. Substantial savings can be achieved only if the staffing level is adapted to the changed personnel requirements.

  1. Separation of prescribing and dispensing in Malaysia: the history and challenges.

    Tiong, John Jeh Lung; Mai, Chun Wai; Gan, Pou Wee; Johnson, James; Mak, Vivienne Sook Li

    2016-08-01

    This article serves as an update to the work by Shafie et al. (2012) which previously reviewed the benefits of policies separating prescribing and dispensing in various countries to advocate its implementation in Malaysia. This article seeks to strengthen the argument by highlighting not only the weaknesses of the Malaysian health care system from the historical, professional and economic viewpoints but also the shortcomings of both medical and pharmacy professions in the absence of separation of dispensing. It also provides a detailed insight into the ongoing initiatives taken to consolidate the role of pharmacists in the health care system in the advent of separation of dispensing. Under the two tier system in Malaysia at present, the separation of prescribing and dispensing is implemented only in government hospitals. The absence of this separation in the private practices has led to possible profit-oriented medical and pharmacy practices which hinder safe and cost-effective delivery of health services. The call for separation of dispensing has gained traction over the years despite various hurdles ranging from the formidable resistance from the medical fraternity to the public's scepticism towards the new policy. With historical testament and present evidence pointing towards the merits of a system in which doctors prescribe and pharmacists dispense, the implementation of this health care model is justified. PMID:26777986

  2. 基于声波技术的管道泄漏检测与定位系统的研究%Research on detection and location system of pipeline leakage based on acoustic wave technology

    付光杰; 赵丹; 赵庆峰; 王士勇

    2015-01-01

    The online real-time leakage detection and location system of natural gas pipeline leak source makes the leakage can be discovered in time,which can confirm leak source location accurately. The economic losses caused by natural gas leakage can be reduced,and it has profound significance for improving automated management level of natural gas transportation pipe-line. By studying and comparative analyzing to pipeline detection technology at home and abroad,acoustic wave technology is ap-plied to leakage detection of gas pipeline. The real-time acoustic wave monitoring and location system for natural gas line leakage was designed by virtual instrument software to proceed signal processing. The leaked acoustic wave signal is proceeded with waveform real-time display,digital filtering,correlated calculation,leakage location and other operations. The automation of pipeline leakage detection was realized.%天然气管道漏点在线实时泄漏监测与定位系统的研究与应用,使得泄漏能够被及时发现并确定泄漏点的位置,从而降低因天然气泄漏造成的经济损失,同时对提高天然气输送管线的自动化管理水平有着深远的意义.通过对国内外各种管道泄漏检测技术的研究和分析比较,采用声波检测方法应用于输气管道的泄漏检测策略,在信号处理方面采用虚拟仪器软件设计了天然气管线声波泄漏实时监测定位系统,对泄漏声波信号进行波形实时显示、数字滤波、相关运算以及泄漏点定位等操作,实现了管线泄漏检测的自动化.

  3. Distributed acoustic sensing: towards partial discharge monitoring

    Rohwetter, Philipp; Eisermann, René; Krebber, Katerina

    2015-09-01

    We report on the successful application of distributed acoustic sensing (DAS) to the detection of partial discharge (PD). A detection limit of about 1 nC discharge magnitude was achieved for PD in a real-scale model of a high voltage termination. Dedicated ultrasonic fibre-optic transducers were interrogated using coherent optical time-domain Rayleigh backscatter reflectometry (C-OTDR). Random quadrature demodulation was employed for retrieving relevant acoustic information from the raw C-OTDR backscatter traces. To our knowledge, our results are a first-time demonstration that quasi-distributed fibre-optic acoustic sensing is a candidate technology for the acoustic partial discharge monitoring of power cable joints and terminations.

  4. Prescribed 3-D Direct Writing of Suspended Micron/Sub-micron Scale Fiber Structures via a Robotic Dispensing System.

    Yuan, Hanwen; Cambron, Scott D; Keynton, Robert S

    2015-01-01

    A 3-axis dispensing system is utilized to control the initiating and terminating fiber positions and trajectory via the dispensing software. The polymer fiber length and orientation is defined by the spatial positioning of the dispensing system 3-axis stages. The fiber diameter is defined by the prescribed dispense time of the dispensing system valve, the feed rate (the speed at which the stage traverses from an initiating to a terminating position), the gauge diameter of the dispensing tip, the viscosity and surface tension of the polymer solution, and the programmed drawing length. The stage feed rate affects the polymer solution's evaporation rate and capillary breakup of the filaments. The dispensing system consists of a pneumatic valve controller, a droplet-dispensing valve and a dispensing tip. Characterization of the direct write process to determine the optimum combination of factors leads to repeatedly acquiring the desired range of fiber diameters. The advantage of this robotic dispensing system is the ease of obtaining a precise range of micron/sub-micron fibers onto a desired, programmed location via automated process control. Here, the discussed self-assembled micron/sub-micron scale 3D structures have been employed to fabricate suspended structures to create micron/sub-micron fluidic devices and bioengineered scaffolds. PMID:26132732

  5. Design, performance validation, and reliability testing of a new photochemical dispense pump

    Bowers, William F.; Hunt, Stephen; Lee, Ben; Anantharaman, Ven; Rice, Mike; Rim, Jung S.

    1992-06-01

    The continued reduction in device linewidths and film thicknesses has led to the need for tighter control of the photochemical dispense process. Accurate and repeatable application of thin films of photoresist is complicated by the need for point-of-use filtration as close to the dispense nozzle as possible. This paper describes the design, validation, and reliability testing of a new photochemical pump whose primary requirements were cleanliness and repeatability. Both the dispense rate and the dispense volume were to be unaffected by changes in temperature, fluid viscosity, filter loading, or air in the filter. The Wafergard GEN-2TM photochemical dispense system is a stepper-motor driven, diaphragm-dispense pump which provides point-of-use filtration to reduce contamination (gels, microbubbles, and particles) and provide precise and repeatable dispense of photochemicals. The pump is a two-stage system in which a 0.1 micrometers stacked disk TeflonTM filter is isolated from the dispense chamber, thus allowing the filtration rate to be uncoupled from the dispense rate. The chemical flowpath is all-Teflon. The dispense diaphragm is hydraulically coupled through a metal bellows to a zero-backlash stepper linear actuator. These design features make the dispense rate, profile, and volume independent of the filter loading. Performance validation testing has been done. Long term (greater than 100,000 cycles) testing using 30 cps positive photoresist with typical operating conditions (2 mL dispense volume at a 2 mL/sec dispense rate through a ten foot 5/32' I.D. section of tubing) showed total volume repeatability to be within +/- 0.02 grams (3 Std Dev). A new method for quantifying the dispense flowrate profile has been developed and used to record the effect of system compliancy on flow dynamics. Wafer coating performance studies using an SVG 90 Series Resist Processing System addressed uniformity and resist consumption. Extensive reliability testing of GEN-2 has been

  6. AST Launch Vehicle Acoustics

    Houston, Janice; Counter, D.; Giacomoni, D.

    2015-01-01

    The liftoff phase induces acoustic loading over a broad frequency range for a launch vehicle. These external acoustic environments are then used in the prediction of internal vibration responses of the vehicle and components which result in the qualification levels. Thus, predicting these liftoff acoustic (LOA) environments is critical to the design requirements of any launch vehicle. If there is a significant amount of uncertainty in the predictions or if acoustic mitigation options must be implemented, a subscale acoustic test is a feasible pre-launch test option to verify the LOA environments. The NASA Space Launch System (SLS) program initiated the Scale Model Acoustic Test (SMAT) to verify the predicted SLS LOA environments and to determine the acoustic reduction with an above deck water sound suppression system. The SMAT was conducted at Marshall Space Flight Center and the test article included a 5% scale SLS vehicle model, tower and Mobile Launcher. Acoustic and pressure data were measured by approximately 250 instruments. The SMAT liftoff acoustic results are presented, findings are discussed and a comparison is shown to the Ares I Scale Model Acoustic Test (ASMAT) results.

  7. Simultaneous measurements of room acoustic parameters using different measuring equipment

    Halmrast, Tor; Gade, Anders Christian; Winsvold, Bjørn

    1996-01-01

    In a cooperation between Stattsbyg, Norway, Norsonic, Norway, and Department of Acoustic Technology, a number of room acoustic parameters have been determined in Oslo Concert Hall. All measurements were carried out on the same day, using the same amplifier, microphone and loudspeaker, and the sam...

  8. Type I IFN Signaling Is Dispensable during Secondary Viral Infection.

    Hosking, Martin P; Flynn, Claudia T; Whitton, J Lindsay

    2016-08-01

    Innate immune responses in general, and type I interferons (T1IFNs) in particular, play an important and often essential role during primary viral infections, by directly combatting the virus and by maximizing the primary adaptive immune response. Several studies have suggested that T1IFNs also contribute very substantially to the secondary (recall) response; they are thought (i) to be required to drive the early attrition of memory T cells, (ii) to support the subsequent expansion of surviving virus-specific memory cells, and (iii) to assist in the suppression and clearance of the infectious agent. However, many of these observations were predicated upon models in which T1IFN signaling was interrupted prior to a primary immune response, raising the possibility that the resulting memory cells might be intrinsically abnormal. We have directly addressed this by using an inducible-Cre model system in which the host remains genetically-intact during the primary response to infection, and in which T1IFN signaling can be effectively ablated prior to secondary viral challenge. We report that, in stark contrast to primary infection, T1IFN signaling is not required during the recall response. IFNαβR-deficient memory CD8+ and CD4+ memory T cells undergo attrition and expansion with kinetics that are indistinguishable from those of receptor-sufficient cells. Moreover, even in the absence of functional T1IFN signaling, the host's immune capacity to rapidly suppress, and then to eradicate, a secondary infection remains intact. Thus, this study shows that T1IFN signaling is dispensable during the recall response to a virus infection. Moreover, two broader implications may be drawn. First, a T cell's requirement for a cytokine is highly dependent on the cell's maturation / differentiation status. Consequently, second, these data underscore the importance of evaluating a gene's impact by modulating its expression or function in a temporally-controllable manner. PMID:27580079

  9. Back bombardment for dispenser and lanthanum hexaboride cathodes

    Bakr, Mahmoud; Kinjo, R.; Choi, Y. W.; Omer, M.; Yoshida, K.; Ueda, S.; Takasaki, M.; Ishida, K.; Kimura, N.; Sonobe, T.; Kii, T.; Masuda, K.; Ohgaki, H.; Zen, H.

    2011-06-01

    The back bombardment (BB) effect limits wide usage of thermionic rf guns. The BB effect induces not only ramping-up of a cathode’s temperature and beam current, but also degradation of cavity voltage and beam energy during a macropulse. This paper presents a comparison of the BB effect for the case of dispenser tungsten-base (DC) and lanthanum hexaboride (LaB6) thermionic rf gun cathodes. For each, particle simulation codes are used to simulate the BB effect and electron beam dynamics in a thermionic rf gun cathode. A semiempirical equation is also used to investigate the stopping range and deposited heat power of BB electrons in the cathode material. A numerical simulation method is used to calculate the change of the cathode temperature and current density during a single macropulse. This is done by solving two differential equations for the rf gun cavity equivalent circuit and one-dimensional thermal diffusion equation. High electron emission and small beam size are required for generation of a high-brightness electron beam, and so in this work the emission properties of the cathode are taken into account. Simulations of the BB effect show that, for a pulse of 6μs duration, the DC cathode experiences a large change in the temperature compared with LaB6, and a change in current density 6 times higher. Validation of the simulation results is performed using experimental data for beam current beyond the gun exit. The experimental data is well reproduced using the simulation method.

  10. Justice Dispensation through the Alternative Dispute Resolution System in India

    Krishna Agrawal

    2015-02-01

    Full Text Available The Law Commission of India in its 222nd report emphasized the need for Alternative Disputes Resolution (ADR for the dispensation of justice, because the courts are inaccessible owing to various factors, e.g., poverty, social and political backwardness, illiteracy, ignorance, procedural formalities and inordinate delay in judgments. During the ancient period the disputes were resolved in an informal manner by neutral third persons or people’s court in villages and it continued till the middle of the 20th century. Unfortunately, after the Independence of India in 1947, this system was dissuaded and the government permitted to continue the adversarial system of justice. In 1980, a committee was set up. It recommended Lok Adalats (People’s Courts. In 1987, the Legal Services Authorities Act was enacted. This Act obligates the states to provide free legal aid to poor persons. Besides this, the Act provides for the establishment of permanent Lok Adalats.This is one of the important modes of ADR. Lok Adalats have been established in all the districts of the country. They bring conciliatory settlement in complicated cases arising out of matrimonial, landlord-tenants, property, insurance and commercial disputes. There are four methods of ADR, viz., negotiation, mediation, conciliation and arbitration. Mediation and arbitration are widely preferred. They are alternatives to litigation. The Arbitration Act for the first time was enacted in 1889 and it was subsequently amended many times. On the objections raised by the Supreme Court of India and also on the adoption of UNCITRAL Model Law on International Commercial Arbitration, in 1996 Arbitration and Conciliation Act was enacted. This law is almost the same as is almost in all the countries.Further, the Government of India established International Centre for Alternative Disputes Resolution (CADR with the objectives of promotion, propagation, and popularizing the settlement of domestic and

  11. Acoustic streaming in microchannels

    Tribler, Peter Muller

    , and experimental results for the streaming-induced drag force dominated motion of particles suspended in a water-filled microchannel supporting a transverse half-wavelength resonance. The experimental and theoretical results agree within a mean relative dierence of approximately 20%, a low deviation given state......This thesis presents studies of boundary-driven acoustic streaming in microfluidic channels, which is a steady flow of the fluid initiated by the interactions of an oscillating acoustic standing wave and the rigid walls of the microchannel. The studies present analysis of the acoustic resonance......, the acoustic streaming flow, and the forces on suspended microparticles. The work is motivated by the application of particle focusing by acoustic radiation forces in medical, environmental and food sciences. Here acoustic streaming is most often unwanted, because it limits the focusability of particles...

  12. Vibro-acoustics

    Nilsson, Anders

    2015-01-01

    This three-volume book gives a thorough and comprehensive presentation of vibration and acoustic theories. Different from traditional textbooks which typically deal with some aspects of either acoustic or vibration problems, it is unique of this book to combine those two correlated subjects together. Moreover, it provides fundamental analysis and mathematical descriptions for several crucial phenomena of Vibro-Acoustics which are quite useful in noise reduction, including how structures are excited, energy flows from an excitation point to a sound radiating surface, and finally how a structure radiates noise to a surrounding fluid. Many measurement results included in the text make the reading interesting and informative. Problems/questions are listed at the end of each chapter and the solutions are provided. This will help the readers to understand the topics of Vibro-Acoustics more deeply. The book should be of interest to anyone interested in sound and vibration, vehicle acoustics, ship acoustics and inter...

  13. Springer handbook of acoustics

    2014-01-01

    Acoustics, the science of sound, has developed into a broad interdisciplinary field encompassing the academic disciplines of physics, engineering, psychology, speech, audiology, music, architecture, physiology, neuroscience, and electronics. The Springer Handbook of Acoustics is also in his 2nd edition an unparalleled modern handbook reflecting this richly interdisciplinary nature edited by one of the acknowledged masters in the field, Thomas Rossing. Researchers and students benefit from the comprehensive contents. This new edition of the Handbook features over 11 revised and expanded chapters, new illustrations, and 2 new chapters covering microphone arrays  and acoustic emission.  Updated chapters contain the latest research and applications in, e.g. sound propagation in the atmosphere, nonlinear acoustics in fluids, building and concert hall acoustics, signal processing, psychoacoustics, computer music, animal bioacousics, sound intensity, modal acoustics as well as new chapters on microphone arrays an...

  14. PREVENTING LITHOGRAPHY-INDUCED MAVERICK YIELD EVENTS WITH A DISPENSE SYSTEM ADVANCED EQUIPMENT CONTROL METHOD

    Jennifer Broggin

    2012-01-01

    As semiconductor manufacturers march to thedrum beat of Moore's Law there is very little roomfor yield maverieks, especially those that can beprevented. Critical process errors are costly andphotolithography is one of the few processes insemiconductor manufacturing where there is anopportunity to correct errors. Small changes inphotoresist-dispensed volume may have severeimpact on film thickness uniformity and can ulti-mately affect patterning It is important to monitorphoto dispense conditions to detect real-timeevents that may have a direct negative impact onprocess yield and be able to react to these eventsas quickly as possible.This paper presents an evaluation of the IntelliGen Mini, a photoresist dispense system manufacturedby Entegris, Inc. This system utilizes advancedequipment control software, known as dispenseconfirmation, to detect variations in photo dis-pense. These variations, caused by bubbles inthe dispense line, valve errors and accidentally-changed chemistries can all create maverick yieldevents that can go undetected until metrology,defeet inspection or wafer final testThe ability of an advanced dispense system todetect events and create alerts is a very powerfultool, but it can be most effective when that infor-mation is collected and analyzed by an automatedsystem. In a modern fabricator this is most likely astatistical process control chart that is monitoringa track's progress and is ready to stop the trackwhen a maverick event occurs or alert personnelto trends they may not otherwise catch with otherinline ntetrology data. Dispense confirmation,when Combined with networking capabilities,can meet this need.After a brief description of the pump, data from sim-ulated yield-affecting events will be examined toevaluate the IntelliGen Mini's ability to detect them.This discussion will eonclude with a brief analysisof the ultilnate time and cost savings of utilizingdispense confirmation with networking capabilitiesto detect and eliminate poorly

  15. Localized Acoustic Surface Modes

    Farhat, Mohamed

    2015-08-04

    We introduce the concept of localized acoustic surface modes (ASMs). We demonstrate that they are induced on a two-dimensional cylindrical rigid surface with subwavelength corrugations under excitation by an incident acoustic plane wave. Our results show that the corrugated rigid surface is acoustically equivalent to a cylindrical scatterer with uniform mass density that can be represented using a Drude-like model. This, indeed, suggests that plasmonic-like acoustic materials can be engineered with potential applications in various areas including sensing, imaging, and cloaking.

  16. Shallow Water Acoustic Laboratory

    Federal Laboratory Consortium — FUNCTION: Supports experimental research where high-frequency acoustic scattering and surface vibration measurements of fluid-loaded and non-fluid-loaded structures...

  17. Handbook of Engineering Acoustics

    Möser, Michael

    2013-01-01

    This book examines the physical background of engineering acoustics, focusing on empirically obtained engineering experience as well as on measurement techniques and engineering methods for prognostics. Its goal is not only to describe the state of art of engineering acoustics but also to give practical help to engineers in order to solve acoustic problems. It deals with the origin, the transmission and the methods of the abating different kinds of air-borne and structure-borne sounds caused by various mechanisms – from traffic to machinery and flow-induced sound. In addition the modern aspects of room and building acoustics, as well as psychoacoustics and active noise control, are covered.

  18. Acoustic dispersive prism

    Esfahlani, Hussein; Karkar, Sami; Lissek, Herve; Mosig, Juan R.

    2016-01-01

    The optical dispersive prism is a well-studied element, which allows separating white light into its constituent spectral colors, and stands in nature as water droplets. In analogy to this definition, the acoustic dispersive prism should be an acoustic device with capability of splitting a broadband acoustic wave into its constituent Fourier components. However, due to the acoustical nature of materials as well as the design and fabrication difficulties, there is neither any natural acoustic counterpart of the optical prism, nor any artificial design reported so far exhibiting an equivalent acoustic behaviour. Here, based on exotic properties of the acoustic transmission-line metamaterials and exploiting unique physical behaviour of acoustic leaky-wave radiation, we report the first acoustic dispersive prism, effective within the audible frequency range 800 Hz-1300 Hz. The dispersive nature, and consequently the frequency-dependent refractive index of the metamaterial are exploited to split the sound waves towards different and frequency-dependent directions. Meanwhile, the leaky-wave nature of the structure facilitates the sound wave radiation into the ambient medium.

  19. Applying of the array transducers' technology for surface acoustic waves materials characterization in the transient regime; Application de la technologie multi-elements a la caracterisation des materiaux par ondes acoustiques de surface en regime impulsionnel

    Frenet, D

    2000-07-01

    In this document we present a theoretical and experimental study which has been led to design a surface acoustic wave device for local characterisation (relatively to the wavelength) of isotropic or anisotropic materials. The device is based on a phased-array transducer of conical shape we have specifically designed for this purpose. It operates in the impulsive mode, in the frequency range of 1-5 MHz. In order to deduce mechanical properties of the material, it is possible to measure the surface wave characteristics (velocity, attenuation,...). Different methods for measuring the wave velocity have been developed taking advantage of from the phased-array technology. The originality of theses methods relies on the fact that the measures are performed without moving the transducer. Consequently, the device requires no additional mechanical system and it is quite compact. In addition, this shortens the characterisation process duration comparatively to the usually available methods (e. g. the V(z) technique). In the theoretical section of this study, a versatile model allowing to simulate in the time harmonic regime as well as in the transient regime, the transmitted field, the field reflected on isotropic or anisotropic planar samples and the output voltage for transducers of arbitrary shapes has been developed. The model has been applied to the phased-array conical transducer as well as to more classical transducers such as planar (rectangular) or focusing (spherically or cylindrically shaped) transducers. It predicts not only the geometrical contributions of the reflected field and signal but also the leaky contributions related to the surface acoustic waves. (author)

  20. What Is an Acoustic Neuroma

    ... org Connect with us! What is an Acoustic Neuroma? Each heading slides to reveal information. Important Points ... Neuroma Important Points To Know About an Acoustic Neuroma An acoustic neuroma, also called a vestibular schwannoma, ...

  1. The design and control of a jetting dispenser for semiconductor electronic packaging driven by a piezostack and a flexible beam

    This paper presents the performance characteristics of a new type of jetting dispenser which can be applicable for modern semiconductor packaging processes. The proposed jetting dispenser is driven by both a piezostack actuator and a flexible beam mechanism. After describing the geometric configuration and operational principle of the dispenser, a mathematical model of the system is derived by considering the dynamic behaviors of structural parts such as the piezostack, the flexible beam, the needle structure, and the adhesive fluid dynamics. In the modeling, a lumped parameter method is employed and the governing equation of the whole dispenser is then formulated by integrating the structural model with the fluid model. Based on the proposed model, significant structural components of the dispenser such as the piezostack, the flexible beam, and the actuating spring are designed in order to achieve operational requirements (needle motion amplitude: up to 0.4 mm; operating frequency: up to 700 Hz). Subsequently, dispensing performances such as the dispensing dot size and flow rate are experimentally evaluated. In addition, a control algorithm is designed and empirically realized to demonstrate some benefits of the proposed jetting dispenser such as accurate controllability of dispensing amount

  2. Humanitarian mine detection by acoustic resonance

    Kercel, S.W.

    1998-03-01

    The JASON Committee at MITRE Corp. was tasked by DARPA to inquire into suitable technologies for humanitarian mine detection. Acoustic resonance was one of the very few technologies that the JASONs determined might be promising for the task, but was as yet unexplored at the time that they conducted their inquiry. The objective of this Seed Money investigation into acoustic resonance was to determine if it would be feasible to use acoustic resonance to provide an improvement to present methods for humanitarian mine detection. As detailed in this report, acoustic resonance methods do not appear to be feasible for this task. Although acoustic resonant responses are relatively easy to detect when they exist, they are very difficult to excite by the non-contact means that must be used for buried objects. Despite many different attempts, this research did not discover any practical means of using sound to excite resonant responses in objects known to have strong resonances. The shaker table experiments did see an effect that might be attributable to the resonance of the object under test, but the effect was weak, and exploited the a priori knowledge of the resonant frequency of the object under test to distinguish it from the background. If experiments that used objects known to have strong acoustic resonances produced such marginal results, this does not seem to be a practical method to detect objects with weak resonances or non-existent resonances. The results of this work contribute to the ORNL countermine initiative. ORNL is exploring several unconventional mine detection technologies, and is proposed to explore others. Since this research has discovered some major pitfalls in non-metallic mine detection, this experience will add realism to other strategies proposed for mine detection technologies. The experiment provided hands-on experience with inert plastic mines under field conditions, and gives ORNL additional insight into the problems of developing practical

  3. [Dispensing specialized component medicines in areas of the State of Rio de Janeiro].

    Lima-Dellamora, Elisangela da Costa; Caetano, Rosangela; Osorio-de-Castro, Claudia Garcia Serpa

    2012-09-01

    The Specialized Pharmaceutical Services Component (CEAF) ensures the dispensing of high-cost medicines for the treatment of specific diseases. The fact that these medicines are mandatory though access is only through legal injunctions, suggests flaws in the management of pharmaceutical services. This paper analyzed adherence to Clinical Protocols and Therapeutic Guidelines (PCDT) in the dispensing of these CEAF medicines. Qualitative research was also conducted in facilities with different characteristics in the State of Rio de Janeiro. It was noted that the lack of adequate structure in the units studied, including trained personnel, compromises the dispensing CEAF medicines in all facilities. The CEAF dispensing procedure, heavily dependent on interaction between prescribers and dispensers, is not carried out as would be expected. It is possible that inadequate performance is also linked to flaws in the planning and organization of services. The results indicate barriers in adherence to PCDT by health professionals, prejudicing health system users and possibly leading them to access medicines by legal means. It is believed that characteristics of the investigated facilities are similar to others in Brazil, and the barriers identified may be the same, compromising healthcare. PMID:22996889

  4. Optimizing Aerosol Dispensers for Mating Disruption of Codling Moth, Cydia pomonella L.

    McGhee, Peter S; Miller, James R; Thomson, Donald R; Gut, Larry J

    2016-07-01

    Experiments were conducted in commercial apple orchards to determine if improved efficiencies in pheromone delivery may be realized by using aerosol pheromone dispensers for codling moth (CM), Cydia pomonella L., mating disruption. Specifically, we tested how reducing: pheromone concentration, period of dispenser operation, and frequency of pheromone emission from aerosol dispensers affected orientational disruption of male CM to pheromone-baited monitoring traps. Isomate® CM MIST formulated with 50 % less codlemone (3.5 mg/ emission) provided orientation disruption equal to the standard commercial formulation (7 mg / emission). Decreased periods of dispenser operation (3 and 6 h) and frequency of pheromone emission (30 and 60 min) provided a level of orientational disruption similar to the current standard protocol of releasing pheromone over a 12 h period on a 15 min cycle, respectively. These three modifications provide a means of substantially reducing the amount of pheromone necessary for CM disruption. The savings accompanying pheromone conservation could lead to increased adoption of CM mating disruption and, moreover, provide an opportunity for achieving higher levels of disruption by increasing dispenser densities. PMID:27369280

  5. Patient attitudes towards a new role for pharmacists: continued dispensing

    Abukres SH

    2014-08-01

    Full Text Available Salem Hasn Abukres, Kreshnik Hoti, Jeffery David Hughes School of Pharmacy, Curtin Health and Innovation Research Institute, Curtin University, Perth, WA, Australia Background: In Australia, “continued dispensing” (CD is a new model for supply of prescription medications. Under specific circumstances, community pharmacists are allowed to dispense a further one month supply of prescription only medications without a valid prescription. It allows continuation and treatment adherence when patients run out of statin and/or oral contraceptive (OC medications, when it is not practical or they fail to plan accordingly to get a new prescription. Objective: The aim of this study was to explore patient attitudes towards a CD model, including any perceived concerns or associated risks with CD prior to its introduction.Methods: An Australia-wide computer-assisted telephone interview survey of statin and OC users aged 18 years or older was conducted in July 2013 prior to implementation of the CD model. A telephone number list was generated via a random number generation function based on a broad breakdown of the Australian population as outlined in the June 2013 Australian Bureau of Statistics data. The sample target for the survey was 300, consisting of 150 statin users and 150 OC users.Results: There were a total of 301 respondents, comprising 151 statin users and 150 OC users. Approximately 37% of all respondents had experienced running out of their medications in the past 12 months, of whom 35.4% had temporarily stopped treatment and 33.6% requested their medication from a pharmacist without a valid prescription. OC users were more likely to run out of their medications (P=0.021. The majority of respondents had a regular pharmacy (86% and therefore would be eligible for CD in the future. The majority of those surveyed had no concerns about CD or perceived it as posing no risks. Concerns raised included consultation privacy and the pharmacist’s lack

  6. Low Frequency Noise Reduction Using Novel Poro-Elastic Acoustic Metamaterials

    Slagle, Adam Christopher

    2014-01-01

    Low frequency noise is a common problem in aircraft and launch vehicles. New technologies must be investigated to reduce this noise while contributing minimal weight to the structure. This thesis investigates passive and active control methods to improve low frequency sound absorption and transmission loss using acoustic metamaterials. The acoustic metamaterials investigated consist of poro-elastic acoustic heterogeneous (HG) metamaterials and microperforated (MPP) acoustic metamaterials. HG ...

  7. Acoustic emission source modeling

    Hora, Petr; Červená, Olga

    2010-01-01

    Roč. 4, č. 1 (2010), s. 25-36. ISSN 1802-680X R&D Projects: GA ČR GA101/09/1630 Institutional research plan: CEZ:AV0Z20760514 Keywords : acoustic emission source * wave propagation * FEM Subject RIV: BI - Acoustics

  8. Acoustic Neuroma Educational Video

    Full Text Available ... Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask Yourself Post-treatment Post-treatment ... Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask Yourself Post-treatment Post-treatment ...

  9. Preserving the acoustical heritage of historical buildings

    Rindel, Jens Holger

    2005-01-01

    The use of virtual reality and auralization techniques has opened new possibilities for the study of acoustical conditions in historic buildings. With reference to some recent and current projects the paper describes the steps in the process and how new technology may be used to overcome some of ...

  10. Ocean acoustic hurricane classification.

    Wilson, Joshua D; Makris, Nicholas C

    2006-01-01

    Theoretical and empirical evidence are combined to show that underwater acoustic sensing techniques may be valuable for measuring the wind speed and determining the destructive power of a hurricane. This is done by first developing a model for the acoustic intensity and mutual intensity in an ocean waveguide due to a hurricane and then determining the relationship between local wind speed and underwater acoustic intensity. From this it is shown that it should be feasible to accurately measure the local wind speed and classify the destructive power of a hurricane if its eye wall passes directly over a single underwater acoustic sensor. The potential advantages and disadvantages of the proposed acoustic method are weighed against those of currently employed techniques. PMID:16454274

  11. Cochlear bionic acoustic metamaterials

    Ma, Fuyin; Wu, Jiu Hui; Huang, Meng; Fu, Gang; Bai, Changan

    2014-11-01

    A design of bionic acoustic metamaterial and acoustic functional devices was proposed by employing the mammalian cochlear as a prototype. First, combined with the experimental data in previous literatures, it is pointed out that the cochlear hair cells and stereocilia cluster are a kind of natural biological acoustic metamaterials with the negative stiffness characteristics. Then, to design the acoustic functional devices conveniently in engineering application, a simplified parametric helical structure was proposed to replace actual irregular cochlea for bionic design, and based on the computational results of such a bionic parametric helical structure, it is suggested that the overall cochlear is a local resonant system with the negative dynamic effective mass characteristics. There are many potential applications in the bandboard energy recovery device, cochlear implant, and acoustic black hole.

  12. Computational Ocean Acoustics

    Jensen, Finn B; Porter, Michael B; Schmidt, Henrik

    2011-01-01

    Since the mid-1970s, the computer has played an increasingly pivotal role in the field of ocean acoustics. Faster and less expensive than actual ocean experiments, and capable of accommodating the full complexity of the acoustic problem, numerical models are now standard research tools in ocean laboratories. The progress made in computational ocean acoustics over the last thirty years is summed up in this authoritative and innovatively illustrated new text. Written by some of the field's pioneers, all Fellows of the Acoustical Society of America, Computational Ocean Acoustics presents the latest numerical techniques for solving the wave equation in heterogeneous fluid–solid media. The authors discuss various computational schemes in detail, emphasizing the importance of theoretical foundations that lead directly to numerical implementations for real ocean environments. To further clarify the presentation, the fundamental propagation features of the techniques are illustrated in color. Computational Ocean A...

  13. Acoustic Signals and Systems

    The Handbook of Signal Processing in Acoustics will compile the techniques and applications of signal processing as they are used in the many varied areas of Acoustics. The Handbook will emphasize the interdisciplinary nature of signal processing in acoustics. Each Section of the Handbook will...... present topics on signal processing which are important in a specific area of acoustics. These will be of interest to specialists in these areas because they will be presented from their technical perspective, rather than a generic engineering approach to signal processing. Non-specialists, or specialists...... from different areas, will find the self-contained chapters accessible and will be interested in the similarities and differences between the approaches and techniques used in different areas of acoustics....

  14. Estimation of inbreeding from ecclesiastical dispensations: application of three procedures to a Spanish case.

    Fuster, Vicente; Colantonio, Sonia

    2002-07-01

    The inbreeding coefficient of a population, estimated from ecclesiastical Roman Catholic dispensations, results from the relative contribution of different degrees of relationships (uncle-niece, first cousin, etc.). The interpopulation comparisons of consanguinity patterns may be obscured by the fact that in 1918 the Roman Catholic Church norm regulating the closest marriageable kinship was modified, limiting the application for an ecclesiastical dispensation to relatives of third degree (second cousins) or closer. Depending on the length of the period before or after the change of regulation, coefficients and rates may differ. Deviation of frequencies for multiple marriages may also occur. The aim of the present paper is to determine how the chosen procedure based on ecclesiastical dispensations may affect results, regarding the inbreeding coefficient, the consanguinity rate, the structure of consanguinity and the close/remote kinship ratio. As a sample case, information from the Gredos mountain range (central Spain) has been used. PMID:12117217

  15. Precision dispensing of small volumes of albumin solder for laser-assisted wound closure

    Sorg, Brian S.; McNally-Heintzelman, Karen M.; Chan, Eric K.; Frederickson, Christopher J.; Welch, Ashley J.

    1999-06-01

    Recent laser-tissue soldering work in our lab has demonstrated the feasibility of building a solder bond from individually coagulated small droplets using a precision pipette for the deposition of the solder droplets. This method of using small, precise volumes of solder to build a bond may result in stronger and more reproducible bonds than coagulating an equivalent large volume of solder all at once. We have investigated the technique further in this study. The solder was dispensed onto the intimal side of a bovine aorta substrate and irradiated with an 808nm diode laser. A bond was created across an incision in the tissue substrate by alternately dispensing and coagulating each small volume of solder, or by coagulating a single large equivalent volume. Acute strength analysis was performed on the solder bond. Future work will concentrate on testing a bench-top solder dispensing device and investigating the feasibility of turning the deice into a prototype tool for clinical applications.

  16. Life-limiting mechanisms in Ba-oxide, Ba-dispenser and Ba-Scandate cathodes

    Gaertner, G.; Barratt, D.

    2005-09-01

    Ba-oxide, Ba-dispenser and Ba-Scandate cathodes have been continuously improved in their emission performance in the past decades. Ba-oxide and Ba-dispenser cathodes are also the dominant types of thermionic cathodes used in most vacuum tube applications. When improvements in emissive properties are introduced, their impact on cathode life - where several years in a vacuum tube environment are typically required - also needs to be known. Hence, the investigation of cathode life-limiting effects is the basis of accelerated life predictions and of further cathode improvement. In this contribution, the main effects limiting the operating life of Ba/BaO-based thermionic cathodes are discussed, especially related to intrinsic dispensation and resupply to the emissive surface. Emission poisoning induced by adsorption of poisonous gases will not be addressed here. We will stress common points and point out the differences between the three types.

  17. Orthotics, prosthesis and mobility aids (OPM dispensation in the Regional Health Department of the 3RD Region of Sao Paulo State

    Camila Caminha Caro

    2014-12-01

    Full Text Available Objective: To identify the process of dispensation of orthotics, prostheses and mobility aids (OPM by the Unified Health System (SUS in the Regional Health Department of the 3rd Region (DRSIII of Sao Paulo state; perform a mapping of the existing physical rehabilitation services in that region; and subsequently correlate the data with applicable laws. Methodology: This is an exploratory cross-sectional qualitative study whose subjects were the main professionals involved in the process of OPM dispensation, or responsible for their acquisition flow in the cities of that region. Data collection was carried out through a semi-structured questionnaire, developed by the researchers themselves, composed of questions aiming to identify the physical rehabilitation centers in the towns, the staff members involved, the provision of assistive technology through SUS, delivery time and existence of waiting lists. Results and discussion: The data were statistically measured, categorized, described and correlated with the current legislation aimed to guarantee access to assistive technology. We observed that the practice around this resource in the 3rd region concentrates in a single care center, causing long waits and poor efficiency of the services provided, in addition to maintaining a paternalistic aspect. Conclusion: This study provides evidence that, although the right to access to assistive technology is legally guaranteed, there are still many difficulties and challenges around this practice.

  18. Patient views on an electronic dispensing device for prepackaged polypharmacy: a qualitative assessment in an ambulatory setting

    Allemann SS

    2015-11-01

    Full Text Available Samuel S Allemann, Kurt E Hersberger, Isabelle ArnetPharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Basel, SwitzerlandObjective: To collect opinions on medication management aids (MMAs in general and on an electronic MMA (e-MMA dispensing prepackaged polypharmacy in sealed pouches.Study setting: The setting involved community-dwelling older adults in Basel, Switzerland, in 2013.Study design: The study involved 1 a 14-day trial with the e-MMA and 2 a focus group to identify general attributes of MMAs, their applicability to the e-MMA, and possible target groups for the e-MMA.Data collection methods: Six participants using long-term polypharmacy and willing to try new technologies completed the 14-day trial and participated in the focus group. Inductive content analysis was performed to extract data.Principal findings: Participants rated ten of 17 general attributes as clearly applicable to the e-MMA and five as unsuitable. Attributes pertained to three interrelating themes: product design, patient support, and living conditions. Envisaged target groups were patients with time-sensitive medication regimens, patients with dementia, the visually impaired, and several patients living together to prevent accidental intake of the wrong medication.Conclusion: The evaluated e-MMA for prepackaged polypharmacy met the majority of the requirements set for an MMA. Patients' living conditions, such as mobility, remain the key determinants for acceptance of an e-MMA.Keywords: pharmaceutical care, medication adherence, medication management aids, automated drug dispensing

  19. Development of suitable potting material for dispenser cathodes of a high power microwave tube

    Highlights: ► Potting material. ► Doped alumina. ► Non-shrinkable. ► Dispenser cathode. ► Microwave tube. - Abstract: The present study aims to develop suitable advanced potting material for modern high performance dispenser cathodes for high power microwave tube through refinement of the alumina microstructure by using suitable dopant. Calcium oxide was selected as a dopant material and the resultant materials were characterized by X-ray diffraction studies and the microstructure monitored by SEM study and EDX analysis. The shrinkage, thermal and electrical properties of the resultant material was evaluated to establish its suitability to function as an advanced potting material.

  20. Adaptive structural vibration control of acoustic deflector

    Ostasevicius, Vytautas; Palevicius, Arvydas; Ragulskis, Minvydas; Dagys, Donatas; Janusas, Giedrius

    2004-06-01

    Vehicle interior acoustics became an important design criterion. Both legal restrictions and the growing demand for comfort, force car manufacturers to optimize the vibro-acoustic behavior of their products. The main source of noise is, of course, the engine, but sometimes some ill-designed cover or other shell structure inside the car resonates and makes unpredicted noise. To avoid this, we must learn the genesis mechanism of such vibrations, having as subject complex 3D shells. The swift development of computer technologies opens the possibility to numerically predict and optimize the vibrations and noises.

  1. Flat acoustic lens by acoustic grating with curled slits

    We design a flat sub-wavelength lens that can focus acoustic wave. We analytically study the transmission through an acoustic grating with curled slits, which can serve as a material with tunable impedance and refractive index for acoustic waves. The effective parameters rely on the geometry of the slits and are independent of frequency. A flat acoustic focusing lens by such acoustic grating with gradient effective refractive index is designed. The focusing effect is clearly observed in simulations and well predicted by the theory. We demonstrate that despite the large impedance mismatch between the acoustic lens and the matrix, the intensity at the focal point is still high due to Fabry–Perot resonance. - Highlights: • Expression of transmission coefficient of an acoustic grating with curled slits. • Non-dispersive and tunable effective medium parameters for the acoustic grating. • A flat acoustic focusing lens with gradient index by using the acoustic grating

  2. Peptide synthesis on glass substrate using acoustic droplet ejector.

    Youngki Choe; Shih-Jui Chen; Eun Sok Kim

    2014-03-01

    This paper describes the synthesis of a 9-mers-long peptide ladder structure of glycine on a modified glass surface using a nanoliter droplet ejector. To synthesize peptide on a glass substrate, SPOT peptide synthesis protocol was followed with a nozzleless acoustic droplet ejector being used to eject about 300 droplets of preactivated amino acid solution to dispense 60 nL of the solution per mer. The coupling efficiency of each mer was measured with FITC fluorescent tag to be 96%, resulting in net 70% efficiency for the whole 9-mer-long peptide of glycine. Usage of a nanoliter droplet ejector for SPOT peptide synthesis increases the density of protein array on a chip. PMID:24235271

  3. An overview of acoustic telemetry

    Drumheller, D.S.

    1992-01-01

    Acoustic telemetry has been a dream of the drilling industry for the past 50 years. It offers the promise of data rates which are one-hundred times greater than existing technology. Such a system would open the door to true logging-while-drilling technology and bring enormous profits to its developers. The basic idea is to produce an encoded sound wave at the bottom of the well, let it propagate up the steel drillpipe, and extract the data from the signal at the surface. Unfortunately, substantial difficulties arise. The first difficult problem is to produce the sound wave. Since the most promising transmission wavelengths are about 20 feet, normal transducer efficiencies are quire low. Compounding this problem is the structural complexity of the bottomhole assembly and drillstring. For example, the acoustic impedance of the drillstring changes every 30 feet and produces an unusual scattering pattern in the acoustic transmission. This scattering pattern causes distortion of the signal and is often confused with signal attenuation. These problems are not intractable. Recent work has demonstrated that broad frequency bands exist which are capable of transmitting data at rates up to 100 bits per second. Our work has also identified the mechanism which is responsible for the observed anomalies in the patterns of signal attenuation. Furthermore in the past few years a body of experience has been developed in designing more efficient transducers for application to metal waveguides. The direction of future work is clear. New transducer designs which are more efficient and compatible with existing downhole power supplies need to be built and tested; existing field test data need to be analyzed for transmission bandwidth and attenuation; and the new and less expensive methods of collecting data on transmission path quality need to be incorporated into this effort. 11 refs.

  4. Dispensação farmacêutica: proposta de um modelo para a prática Dispensation of pharmaceuticals: proposal of a model for dispensation

    Daniela Angonesi

    2011-09-01

    Full Text Available A dispensação é uma atividade farmacêutica que não pode se restringir apenas à entrega do medicamento. O farmacêutico deve promover as condições para que o paciente faça uso do medicamento da melhor maneira possível. Como se trata de uma atividade profissional, e assim como foi estabelecido para a atenção farmacêutica, a dispensação também deve possuir uma filosofia de prática, um processo de cuidado e um sistema de gestão da prática. Este trabalho propõe uma nova definição de dispensação e descreve os seus elementos centrais considerando a realidade dos estabelecimentos farmacêuticos de forma que possa efetivamente ser implementada.The dispensation of pharmaceuticals is an activity that cannot be restricted only to the delivery of medication. The pharmacist must ensure various conditions to ensure that the patient uses the medication in the best possible manner. As it is a professional activity and has been established for pharmaceutical care, dispensation should also have a philosophy of practice, a process of care, and a system for managing the practice. This paper proposes a new definition of dispensation and describes its central elements, considering the reality of established pharmacists, so that it can be effectively implemented.

  5. From Architectural Acoustics to Acoustical Architecture Using Computer Simulation

    Schmidt, Anne Marie Due; KIRKEGAARD, Poul Henning

    2005-01-01

    Architectural acoustics design has in the past been based on simple design rules. However, with a growing complexity in architectural acoustics and the emergence of room acoustic simulation programmes with considerable potential, it is now possible to subjectively analyse and evaluate acoustic properties prior to the actual construction of a building. With the right tools applied, acoustic design can become an integral part of the architectural design process. The aim of this paper is to inve...

  6. Underwater Applications of Acoustical Holography

    P. C. Mehta

    1984-01-01

    Full Text Available The paper describes the basic technique of acoustical holography. Requirements for recording the acoustical hologram are discussed with its ability for underwater imaging in view. Some practical systems for short-range and medium-range imaging are described. The advantages of acoustical holography over optical imaging, acoustical imaging and sonars are outlined.

  7. Predicting Acoustics in Class Rooms

    Christensen, Claus Lynge; Rindel, Jens Holger

    2005-01-01

    Typical class rooms have fairly simple geometries, even so room acoustics in this type of room is difficult to predict using today's room acoustic computer modeling software. The reasons why acoustics of class rooms are harder to predict than acoustics of complicated concert halls might be...

  8. Tunable acoustic metamaterials

    Babaee, Sahab; Viard, Nicolas; Fang, Nicholas; Bertoldi, Katia

    2015-03-01

    We report a new class of active and switchable acoustic metamaterials composed of three-dimensional stretchable chiral helices arranged on a two-dimensional square lattice. We investigate the propagation of sounds through the proposed structure both numerically and experimentally and find that the deformation of the helices can be exploited as a novel and effective approach to control the propagation of acoustic waves. The proposed concept expands the ability of existing acoustic metamaterials since we demonstrate that the deformation can be exploited to turn on or off the band gap, opening avenues for the design of adaptive noise-cancelling devices.

  9. A Low-Cost, Normally Closed, Solenoid Valve for Non-Contact Dispensing in the Sub-µL Range

    Peter Koltay

    2013-02-01

    Full Text Available We present a disposable, normally closed, non-contact dispensing valve for the sub-µL range. The miniaturized solenoid valve (diameter: 8 mm, height: 27.25 mm is compatible to standard Luer-Lock interfaces. A highly dynamic actuation principle enables opening times down to 1 ms. The dispensing performance was evaluated for water (η = 1.03 mPas and a 66% (w/w glycerol/water solution (η = 16.98 mPas, at pressures varying from 200 to 800 mbar. The experimentally determined minimal dispensing volume was 163 nL (CV 1.6% for water and 123 nL (CV 4.5% for 66% (w/w glycerol/water. The low-cost polymer valve enables high precision dispensing of liquid volumes down to the lower end of the sub-µL range comparable to high-end non-disposable micro-dispensing valves.

  10. Acoustic Resonator Optimisation for Airborne Particle Manipulation

    Devendran, Citsabehsan; Billson, Duncan R.; Hutchins, David A.; Alan, Tuncay; Neild, Adrian

    Advances in micro-electromechanical systems (MEMS) technology and biomedical research necessitate micro-machined manipulators to capture, handle and position delicate micron-sized particles. To this end, a parallel plate acoustic resonator system has been investigated for the purposes of manipulation and entrapment of micron sized particles in air. Numerical and finite element modelling was performed to optimise the design of the layered acoustic resonator. To obtain an optimised resonator design, careful considerations of the effect of thickness and material properties are required. Furthermore, the effect of acoustic attenuation which is dependent on frequency is also considered within this study, leading to an optimum operational frequency range. Finally, experimental results demonstrated good particle levitation and capture of various particle properties and sizes ranging to as small as 14.8 μm.

  11. Phononic crystals and acoustic metamaterials

    Ming-Hui Lu; Liang Feng; Yan-Feng Chen

    2009-01-01

    Phononic crystals have been proposed about two decades ago and some important characteristics such as acoustic band structure and negative refraction have stimulated fundamental and practical studies in acoustic materials and devices since then. To carefully engineer a phononic crystal in an acoustic “atom” scale, acoustic metamaterials with their inherent deep subwavelength nature have triggered more exciting investigations on negative bulk modulus and/or negative mass density. Acoustic surf...

  12. Effective acoustic modeling for robust speaker recognition

    Hasan Al Banna, Taufiq

    Robustness due to mismatched train/test conditions is the biggest challenge facing the speaker recognition community today, with transmission channel and environmental noise degradation being the prominent factors. Performance of state-of-the art speaker recognition methods aim at mitigating these factors by effectively modeling speech in multiple recording conditions, so that it can learn to distinguish between inter-speaker and intra-speaker variability. The increasing demand and availability of large development corpora introduces difficulties in effective data utilization and computationally efficient modeling. Traditional compensation strategies operate on higher dimensional utterance features, known as supervectors, which are obtained from the acoustic modeling of short-time features. Feature compensation is performed during front-end processing. Motivated by the covariance structure of conventional acoustic features, we envision that feature normalization and compensation can be integrated into the acoustic modeling. In this dissertation, we investigate the following fundamental research challenges: (i) analysis of data requirements for effective and efficient background model training, (ii) introducing latent factor analysis modeling of acoustic features, (iii) integration of channel compensation strategies in mixture-models, and (iv) development of noise robust background models using factor analysis. The effectiveness of the proposed solutions are demonstrated in various noisy and channel degraded conditions using the recent evaluation datasets released by the National Institute of Standards and Technology (NIST). These research accomplishments make an important step towards improving speaker recognition robustness in diverse acoustic conditions.

  13. Mobile platform for acoustic mine detection applications

    Libbey, Brad; Fenneman, Douglas; Burns, Brian

    2005-06-01

    Researchers in academia have successfully demonstrated acoustic landmine detection techniques. These typically employ acoustic or seismic sources to induce vibration in the mine/soil system, and use vibration sensors such as laser vibrometers or geophones to measure the resultant surface motion. These techniques exploit the unique mechanical properties of landmines to discriminate the vibration response of a buried mine from an off-target measurement. The Army requires the ability to rapidly and reliably scan an area for landmines and is developing a mobile platform at NVESD to meet this requirement. The platform represents an initial step toward the implementation of acoustic mine detection technology on a representative field vehicle. The effort relies heavily on the acoustic mine detection cart system developed by researchers at the University of Mississippi and Planning Systems, Inc. The NVESD platform consists of a John Deere E-gator configured with a robotic control system to accurately position the vehicle. In its present design, the E-gator has been outfitted with an array of laser vibrometers and a bank of loudspeakers. Care has been taken to ensure that the vehicle"s mounting hardware and data acquisition algorithms are sufficiently robust to accommodate the implementation of other sensor modalities. A thorough discussion of the mobile platform from its inception to its present configuration will be provided. Specific topics to be addressed include the vehicle"s control and data acquisition systems. Preliminary results from acoustic mine detection experiments will also be presented.

  14. Acoustic integrated extinction

    Norris, Andrew N

    2015-01-01

    The integrated extinction (IE) is defined as the integral of the scattering cross-section as a function of wavelength. Sohl et al. [1] derived an IE expression for acoustic scattering that is causal, i.e. the scattered wavefront in the forward direction arrives later than the incident plane wave in the background medium. The IE formula was based on electromagnetic results, for which scattering is causal by default. Here we derive a formula for the acoustic IE that is valid for causal and non-causal scattering. The general result is expressed as an integral of the time dependent forward scattering function. The IE reduces to a finite integral for scatterers with zero long-wavelength monopole and dipole amplitudes. Implications for acoustic cloaking are discussed and a new metric is proposed for broadband acoustic transparency.

  15. Acoustics Noise Test Cell

    Federal Laboratory Consortium — The Acoustic Noise Test Cell at the NASA/Caltech Jet Propulsion Laboratory (JPL) is located adjacent to the large vibration system; both are located in a class 10K...

  16. Compact acoustic refrigerator

    Bennett, Gloria A.

    1992-01-01

    A compact acoustic refrigeration system actively cools components, e.g., electrical circuits (22), in a borehole environment. An acoustic engine (12, 14) includes first thermodynamic elements (12) for generating a standing acoustic wave in a selected medium. An acoustic refrigerator (16, 26, 28) includes second thermodynamic elements (16) located in the standing wave for generating a relatively cold temperature at a first end of the second thermodynamic elements (16) and a relatively hot temperature at a second end of the second thermodynamic elements (16). A resonator volume (18) cooperates with the first and second thermodynamic elements (12, 16) to support the standing wave. To accommodate the high heat fluxes required for heat transfer to/from the first and second thermodynamic elements (12, 16), first heat pipes (24, 26) transfer heat from the heat load (22) to the second thermodynamic elements (16) and second heat pipes (28, 32) transfer heat from first and second thermodynamic elements (12, 16) to the borehole environment.

  17. Acoustics lecturing in Mexico

    Beristain, Sergio

    2002-11-01

    Some thirty years ago acoustics lecturing started in Mexico at the National Polytechnic Institute in Mexico City, as part of the Bachelor of Science degree in Communications and Electronics Engineering curricula, including the widest program on this field in the whole country. This program has been producing acoustics specialists ever since. Nowadays many universities and superior education institutions around the country are teaching students at the B.Sc. level and postgraduate level many topics related to acoustics, such as Architectural Acoustics, Seismology, Mechanical Vibrations, Noise Control, Audio, Audiology, Music, etc. Also many institutions have started research programs in related fields, with participation of medical doctors, psychologists, musicians, engineers, etc. Details will be given on particular topics and development.

  18. Acoustic Igniter Project

    National Aeronautics and Space Administration — An acoustic igniter eliminates the need to use electrical energy to drive spark systems to initiate combustion in liquid-propellant rockets. It does not involve the...

  19. Thermal Acoustic Fatigue Apparatus

    Federal Laboratory Consortium — The Thermal Acoustic Fatigue Apparatus (TAFA) is a progressive wave tube test facility that is used to test structures for dynamic response and sonic fatigue due to...

  20. Acoustic Neuroma Educational Video

    Full Text Available ... treatment Summary Types Of Post-treatment Issues Resources Medical Resources Considerations When Selecting a Healthcare Professional Healthcare ... ANA? Mission Statement Board of Directors ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic Neuroma ...

  1. Acoustic coherent perfect absorbers

    In this paper, we explore the possibility of achieving acoustic coherent perfect absorbers. Through numerical simulations in two dimensions, we demonstrate that the energy of coherent acoustic waves can be totally absorbed by a fluid absorber with specific complex mass density or bulk modulus. The robustness of such absorbing systems is investigated under small perturbations of the absorber parameters. We find that when the resonance order is the lowest and the size of the absorber is comparable to the wavelength in the background, the phenomenon of perfect absorption is most stable. When the wavelength inside both the background and the absorber is much larger than the size of the absorber, perfect absorption is possible when the mass density of the absorber approaches the negative value of the background mass density. Finally, we show that by using suitable dispersive acoustic metamaterials, broadband acoustic perfect absorption may be achieved. (papers)

  2. Ocean acoustic reverberation tomography.

    Dunn, Robert A

    2015-12-01

    Seismic wide-angle imaging using ship-towed acoustic sources and networks of ocean bottom seismographs is a common technique for exploring earth structure beneath the oceans. In these studies, the recorded data are dominated by acoustic waves propagating as reverberations in the water column. For surveys with a small receiver spacing (e.g., tomography, is developed that uses the travel times of direct and reflected waves to image ocean acoustic structure. Reverberation tomography offers an alternative approach for determining the structure of the oceans and advancing the understanding of ocean heat content and mixing processes. The technique has the potential for revealing small-scale ocean thermal structure over the entire vertical height of the water column and along long survey profiles or across three-dimensional volumes of the ocean. For realistic experimental geometries and data noise levels, the method can produce images of ocean sound speed on a smaller scale than traditional acoustic tomography. PMID:26723303

  3. Autonomous Acoustic Receiver System

    Federal Laboratory Consortium — FUNCTION: Collects underwater acoustic data and oceanographic data. Data are recorded onboard an ocean buoy and can be telemetered to a remote ship or shore station...

  4. Container with heat or cold dispensing material comprising hydrogel with crosslinked hydrophilic polymer

    Van Turnhout, J.

    2000-01-01

    PCT No. PCT/NL97/00102 Sec. 371 Date Oct. 20, 1998 Sec. 102(e) Date Oct. 20, 1998 PCT Filed Mar. 3, 1997 PCT Pub. No. WO97/33950 PCT Pub. Date Sep. 18, 1997A device for storing and gradually dispensing heat or cold includes a container having a partially heat-conducting wall enclosing a space with m

  5. Root Cause Analysis of Water Wastage in Hot - Cold Water Dispenser

    Sunil Kokane

    2015-03-01

    Full Text Available Hot - Cold Water Dispenser is a high end kitchen product mounted on sink of kitchen to meet the requirement of instant hot and cold water as desired. It provides cold water at ambient temperature and hot water at near boiling temperature of about 97ºC to meet the instant water need. It was reported from few users, small amount of unnecessary water get dispensed from the Hot - Cold Water Dispenser during the idle conditions. This is undesirable and affecting on the overall performance of product. This paper briefs the available Root Cause Analysis and process to select the suitable method to find out the root cause of problem. From the available methods, Fault Tree Analysis was found to be most suitable method. The paper describes this method in length. Fault Tree Analysis is used as the scientific approach to find the root cause of problem of water dripping in Hot - Cold Water Dispenser at idle condition. It makes use of a graphical representation of the major faults associated with the product, the causes for the faults, and potential countermeasures. It is found that the FTA tool helps to identify areas of concern for new product design as well as for improvement of existing products.

  6. Ultrasound aided smooth dispensing for high viscoelastic epoxy in microelectronic packaging.

    Chen, Yun; Li, Han-Xiong; Shan, Xiuyang; Gao, Jian; Chen, Xin; Wang, Fuliang

    2016-01-01

    Epoxy dispensing is one of the most critical processes in microelectronic packaging. However, due its high viscoelasticity, dispensing of epoxy is extremely difficult, and a lower viscoelasticity epoxy is desired to improve the process. In this paper, a novel method is proposed to achieve a lowered viscoelastic epoxy by using ultrasound. The viscoelasticity and molecular structures of the epoxies were compared and analyzed before and after experimentation. Different factors of the ultrasonic process, including power, processing time and ultrasonic energy, were studied in this study. It is found that elasticity is more sensitive to ultrasonic processing while viscosity is little affected. Further, large power and long processing time can minimize the viscoelasticity to ideal values. Due to the reduced loss modulus and storage modulus after ultrasonic processing, smooth dispensing is demonstrated for the processed epoxy. The subsequently color temperature experiments show that ultrasonic processing will not affect LED's lighting. It is clear that the ultrasonic processing will have good potential to aide smooth dispensing for high viscoelastic epoxy in electronic industry. PMID:26384878

  7. MICROBIO : A web-based program for processing and evaluation of microbiological controls on aseptic dispensing

    Postma, D.J.; Boom, F.A.; Bijleveld, Y.A.; Touw, D.J.; Veenbaas, T.; Essink-Tjebbes, C.M.; Verbrugge, P.

    2012-01-01

    Background: According to the Dutch GMP-hospital pharmacy directive (1) three types of microbiological controls are required when aseptic dispensing is performed: 1. microbiological monitoring of the air in the working area, the gloved hands of the operator and the work surface at the critical place

  8. 30 CFR 57.4262 - Underground transformer stations, combustible liquid storage and dispensing areas, pump rooms...

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Underground transformer stations, combustible... and Control Firefighting Equipment § 57.4262 Underground transformer stations, combustible liquid storage and dispensing areas, pump rooms, compressor rooms, and hoist rooms. Transformer stations,...

  9. 21 CFR 1306.07 - Administering or dispensing of narcotic drugs.

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Administering or dispensing of narcotic drugs. 1306.07 Section 1306.07 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... an incidental adjunct to medical or surgical treatment of conditions other than addiction, or...

  10. Correlation of emission capability and longevity of dispenser cathodes with characteristics of tungsten powders

    The intercorrelation of tungsten powder properties, such as grain size, distribution and morphology, and porous matrix parameters with electron emission capability and longevity of Ba dispenser cathodes are investigated for three different grain morphologies. Best results of tungsten cathode life were found for isoaxis polyhedron morphology in combination with certain powder and matrix parameters

  11. Correlation of emission capability and longevity of dispenser cathodes with characteristics of tungsten powders

    Melnikova, Irina P.; Vorozheikin, Victor G.; Usanov, Dmitry A.

    2003-06-01

    The intercorrelation of tungsten powder properties, such as grain size, distribution and morphology, and porous matrix parameters with electron emission capability and longevity of Ba dispenser cathodes are investigated for three different grain morphologies. Best results of tungsten cathode life were found for isoaxis polyhedron morphology in combination with certain powder and matrix parameters.

  12. Relative work function, surface composition and topography of ``pedigreed'' impregnated tungsten dispenser cathodes

    Tomich, D. H.; Mescher, J. A.; Wittberg, T. N.; Grant, J. T.

    1985-12-01

    A study has been made of the variation in work function, surface composition, and topography of 5:3:2 impregnated tungsten dispenser cathodes made under carefully controlled conditions (pedigreed cathodes). Despite these conditions several cathodes had unexpected deposits on their emitting surfaces, and one showed a variation in work function and composition across the surface during activation.

  13. TRAPPING YELLOWJACKETS (HYMENOPTERA: VESPIDAE) WITH HEPTYL BUTYRATE EMITTED FROM CONTROLLED-RELEASE DISPENSERS

    Numbers of workers of Vespula pensylvanica (Saussure) (western yellowjacket) and V. atropilosa (Sladen) trapped with heptyl butyrate in Washington increased with increased release of the attractant from vial dispensers, up to an estimated 2.3 milligrams heptyl butyrate per hour. Vespula germanica F...

  14. The knowledge of emergency contraception and dispensing practices of Patent Medicine Vendors in South West Nigeria.

    Fayemi, Mojisola M; Oduola, Olufemi L; Ogbuji, Queen C; Osinowo, Kehinde A; Oyewo, Adejoke E; Osiberu, Olabimpe M

    2010-09-01

    Patent Medicine Vendors (PMVs) can play a critical role in increasing access to emergency contraceptive pills (ECPs) in developing countries, but few studies have examined their knowledge and dispensing practices. Using cluster sampling, the authors selected and interviewed 97 PMVs (60.8 per cent female) in Oyo and Ogun States of Nigeria to assess their knowledge, dispensing practices, and referral for ECPs. About one-third (27.8 per cent) of respondents were not aware of ECPs, and only half knew that ECPs could prevent pregnancy. Forty per cent had ever dispensed ECPs. Reasons proffered by those who do not dispense ECPs included barriers from the State Ministry of Health, police, other regulatory agencies, and religious beliefs. Only 50.5 per cent have referral arrangements for clients. Strategies to increase access to ECPs through PMVs include training on counseling techniques and referral, effective government regulation, and community involvement. Where unsafe abortion is a major cause of maternal mortality, these strategies offer protection for many women in the future. PMID:20805800

  15. Close up of the glue dispenser. The white lines on the green frames are theapplied glue.

    Bernd Surrow

    1999-01-01

    The gantry motion control along with the pneumatic glue dispenser system allows precise control of the amount of glue applied to theframe. The glue is a special room temperature cure silicone basedglue chosen to minimize surface stresses on the silicon sensors dueto differential temperature contraction.

  16. Acoustic emission source modeling

    Hora, Petr; Červená, Olga

    Plzeň : University of West Bohemia, 2009 - (Adámek, V.; Zajíček, M.). s. 1-2 ISBN 978-80-7043-824-4. [Výpočtová mechanika 2009. 09.11.2009-11.11.2009, Nečtiny] R&D Projects: GA ČR GA101/09/1630 Institutional research plan: CEZ:AV0Z20760514 Keywords : acoustic emission source * wave propagation * FEM Subject RIV: BI - Acoustics

  17. The autonomous acoustic buoy

    Pellicer, Francisco; Reitsma, Robert; Agüera, Joaquín; Marinas, Alexandra

    2013-01-01

    The Acoustic Buoy is a project between the Laboratory of Applied Bioacoustics (LAB) and the Universitat Politècnica de Catalunya (UPC). In areas that the human activities produce high noise levels, such as oil exploration or construction, there is a need to monitor the environment for the presence of cetaceans. Another need is for fishing, to prevent endangered species from being killed. This can be done with an Autonomous Acoustic Buoy (AAB). Mooring or anchoring at to the seaflo...

  18. Anal acoustic reflectometry

    Mitchell, Peter J; Klarskov, Niels; Telford, Karen J; Hosker, Gordon L; Lose, Gunnar; Kiff, Edward S

    2011-01-01

    Anal acoustic reflectometry is a new technique of assessing anal sphincter function. Five new variables reflecting anal canal function are measured: the opening and closing pressure, the opening and closing elastance, and hysteresis.......Anal acoustic reflectometry is a new technique of assessing anal sphincter function. Five new variables reflecting anal canal function are measured: the opening and closing pressure, the opening and closing elastance, and hysteresis....

  19. Wavefront modulation and subwavelength diffractive acoustics with an acoustic metasurface.

    Xie, Yangbo; Wang, Wenqi; Chen, Huanyang; Konneker, Adam; Popa, Bogdan-Ioan; Cummer, Steven A

    2014-01-01

    Metasurfaces are a family of novel wavefront-shaping devices with planar profile and subwavelength thickness. Acoustic metasurfaces with ultralow profile yet extraordinary wave manipulating properties would be highly desirable for improving the performance of many acoustic wave-based applications. However, designing acoustic metasurfaces with similar functionality to their electromagnetic counterparts remains challenging with traditional metamaterial design approaches. Here we present a design and realization of an acoustic metasurface based on tapered labyrinthine metamaterials. The demonstrated metasurface can not only steer an acoustic beam as expected from the generalized Snell's law, but also exhibits various unique properties such as conversion from propagating wave to surface mode, extraordinary beam-steering and apparent negative refraction through higher-order diffraction. Such designer acoustic metasurfaces provide a new design methodology for acoustic signal modulation devices and may be useful for applications such as acoustic imaging, beam steering, ultrasound lens design and acoustic surface wave-based applications. PMID:25418084

  20. Ecological Insights from Pelagic Habitats Acquired Using Active Acoustic Techniques

    Benoit-Bird, Kelly J.; Lawson, Gareth L.

    2016-01-01

    Marine pelagic ecosystems present fascinating opportunities for ecological investigation but pose important methodological challenges for sampling. Active acoustic techniques involve producing sound and receiving signals from organisms and other water column sources, offering the benefit of high spatial and temporal resolution and, via integration into different platforms, the ability to make measurements spanning a range of spatial and temporal scales. As a consequence, a variety of questions concerning the ecology of pelagic systems lend themselves to active acoustics, ranging from organism-level investigations and physiological responses to the environment to ecosystem-level studies and climate. As technologies and data analysis methods have matured, the use of acoustics in ecological studies has grown rapidly. We explore the continued role of active acoustics in addressing questions concerning life in the ocean, highlight creative applications to key ecological themes ranging from physiology and behavior to biogeography and climate, and discuss emerging avenues where acoustics can help determine how pelagic ecosystems function.

  1. Frequency, types, and potential clinical significance of medication-dispensing errors

    Xavier Bohand

    2009-01-01

    Full Text Available INTRODUCTION AND OBJECTIVES: Many dispensing errors occur in the hospital, and these can endanger patients. The purpose of this study was to assess the rate of dispensing errors by a unit dose drug dispensing system, to categorize the most frequent types of errors, and to evaluate their potential clinical significance. METHODS: A prospective study using a direct observation method to detect medication-dispensing errors was used. From March 2007 to April 2007, "errors detected by pharmacists" and "errors detected by nurses" were recorded under six categories: unauthorized drug, incorrect form of drug, improper dose, omission, incorrect time, and deteriorated drug errors. The potential clinical significance of the "errors detected by nurses" was evaluated. RESULTS: Among the 734 filled medication cassettes, 179 errors were detected corresponding to a total of 7249 correctly fulfilled and omitted unit doses. An overall error rate of 2.5% was found. Errors detected by pharmacists and nurses represented 155 (86.6% and 24 (13.4% of the 179 errors, respectively. The most frequent types of errors were improper dose (n = 57, 31.8% and omission (n = 54, 30.2%. Nearly 45% of the 24 errors detected by nurses had the potential to cause a significant (n = 7, 29.2% or serious (n = 4, 16.6% adverse drug event. CONCLUSIONS: Even if none of the errors reached the patients in this study, a 2.5% error rate indicates the need for improving the unit dose drug-dispensing system. Furthermore, it is almost certain that this study failed to detect some medication errors, further arguing for strategies to prevent their recurrence.

  2. International Space Station USOS Potable Water Dispenser On-Orbit Functionality Versus Design

    Toon, Katherine P.; Lovell, Randal W.

    2010-01-01

    The International Space Station (ISS) currently provides potable water dispensing for rehydrating crewmember food and drinking packages. There is one system located in the United States On-orbit Segment (USOS) and one system in the Russian Segment. Shuttle mission STS-126 delivered the USOS Potable Water Dispenser (PWD) to ISS on ULF2; subsequent activation occurred on November 2008. The PWD is capable of supporting an ISS crew of six, but nominally supplies only half this crew size. The PWD design provides incremental quantities of hot and ambient temperature potable water to US food and beverage packages. PWD receives iodinated water from the US Water Recovery System (WRS) Fuel Cell Water Bus, which feeds from the Water Processing Assembly (WPA). The PWD removes the biocidal iodine to make the water potable prior to dispensing. A heater assembly contained within the unit supplies up to 2.0 L of hot water (65 to 93 ?C) every 30 min. During a single meal, this quantity of water supports three to four crewmembers? food rehydration and beverages. The unit design has a functional life expectancy of 10 years, with replacement of limited life items, such as filters. To date, the PWD on-orbit performance is acceptable. Since activation of the PWD, there were several differences between on-orbit functionality and expected performance of hardware design. The comparison of on-orbit functionality to performance of hardware design is discussed for the following key areas: 1) microbial contamination, 2) no-dispense and water leakage scenarios, and 3) under-dispense scenarios.

  3. International Space Station USOS Potable Water Dispenser On-Orbit Functionality vs Design

    Toon, Katherine P.; Lovell, Randal W.

    2009-01-01

    The International Space Station (ISS) currently provides potable water dispensing for rehydrating crewmembers food and drinking packages with one system located in the United States On-orbit Segment (USOS) and one system in the Russian Segment. The USOS Potable Water Dispenser (PWD) was delivered to ISS on ULF2, Shuttle Mission STS-126, and was subsequently activated in November 2008. The PWD activation on ISS is capable of supporting an ISS crew of six but nominally supplies only half the crew. The PWD is designed to provide incremental quantities of hot and ambient temperature potable water to US style food packages. PWD receives iodinated water from the US Laboratory Fuel Cell Water Bus, which is fed from the Water Processing Assembly (WPA). The PWD removes the biocidal iodine to make the water potable prior to dispensing. A heater assembly contained within the unit supplies up to 2.0 liters of hot water (65 to 93oC) every thirty minutes. This quantity supports three to four crewmembers to rehydrate their food and beverages from this location during a single meal. The unit is designed to remain functional for up to ten years with replacement of limited life items such as filters. To date, the PWD on-orbit performance has been acceptable. Since activation of the PWD, there have been several differences between on-orbit functionality and expected performance of hardware design. The comparison of on-orbit functionality to performance of hardware design is outlined for the following key areas: microbiology, PWD to food package water leakage, no-dispense scenarios, under-dispense scenarios, and crewmember feedback on actual on-orbit use.

  4. Microstructure and work function of dispenser cathode coatings: Effects on thermionic emission

    Swartzentruber, Phillip

    Dispenser cathodes emit electrons through thermionic emission and are a critical component of space-based and telecommunication devices. The emission of electrons is enhanced when coated with a refractory metal such as osmium (Os), osmium-ruthenium (Os-Ru), or iridium (Ir). In this work the microstructure, thermionic emission, and work function of thin film Os-Ru coatings were studied in order to relate microstructural properties and thermionic emission. Os-Ru thin film coatings were prepared through magnetron sputtering and substrate biasing to produce films with an array of preferred orientations, or texture. The effect of texture on thermionic emission was studied in detail through closely-spaced diode testing, SEM imaging, and x-ray diffraction. Results indicated that there was a strong correlation with emission behavior and specific preferred orientations. An ultra-high vacuum compatible Kelvin Probe was used to measure the work function of W-Os-Ru ternary alloy films to determine the effect W interdiffusion has on work function. The results indicated that a high work function alloy coating corresponded to low work function cathodes, as expected. It was inferred that a high work function alloy coating results in a low work function cathode because it aligns more closely with ionization energy of Ba. The results also proved that this method of evaluating dispenser cathode coatings can distinguish small variations in microstructure and composition and may be a beneficial tool in the development of improved dispenser cathode coatings. A novel experimental apparatus was constructed to measure the work function of dispenser cathode coatings in-vacuo using the ultra-high vacuum Kelvin Probe. The apparatus is capable of activating cathodes at high temperature and measuring the work function at elevated temperature. The design of this apparatus allows for more rapid evaluation of dispenser cathode coatings.

  5. THE INFLUENCE OF WAVE PATTERNS AND FREQUENCY ON THERMO-ACOUSTIC COOLING EFFECT

    CHEN BAIMAN

    2011-06-01

    Full Text Available With the increasing environmental challenges, the search for an environmentally benign cooling technology that has simple and robust architecture continues. Thermo-acoustic refrigeration seems to be a promising candidate to fulfil these requirements. In this study, a simple thermo-acoustic refrigeration system was fabricated and tested. The thermo-acoustic refrigerator consists of acoustic driver (loudspeaker, resonator, stack, vacuum system and testing system. The effect of wave patterns and frequency on thermo-acoustic cooling effect was studied. It was found that a square wave pattern would yield superior cooling effects compared to other wave patterns tested.

  6. Acoustic comfort in eating establishments

    Svensson, David; Jeong, Cheol-Ho; Brunskog, Jonas

    2014-01-01

    The subjective concept of acoustic comfort in eating establishments has been investigated in this study. The goal was to develop a predictive model for the acoustic comfort, by means of simple objective parameters, while also examining which other subjective acoustic parameters could help explain...... the feeling of acoustic comfort. Through several layers of anal ysis, acoustic comfort was found to be rather complex, and could not be explained entirely by common subjective parameters such as annoyance, intelligibility or privacy. A predictive model for the mean acoustic comfort for an eating...

  7. Phononic crystals and acoustic metamaterials

    Ming-Hui Lu

    2009-12-01

    Full Text Available Phononic crystals have been proposed about two decades ago and some important characteristics such as acoustic band structure and negative refraction have stimulated fundamental and practical studies in acoustic materials and devices since then. To carefully engineer a phononic crystal in an acoustic “atom” scale, acoustic metamaterials with their inherent deep subwavelength nature have triggered more exciting investigations on negative bulk modulus and/or negative mass density. Acoustic surface evanescent waves have also been recognized to play key roles to reach acoustic subwavelength imaging and enhanced transmission.

  8. From Architectural Acoustics to Acoustical Architecture Using Computer Simulation

    Schmidt, Anne Marie Due; Kirkegaard, Poul Henning

    2005-01-01

    Architectural acoustics design has in the past been based on simple design rules. However, with a growing complexity in architectural acoustics and the emergence of room acoustic simulation programmes with considerable potential, it is now possible to subjectively analyse and evaluate acoustic...... properties prior to the actual construction of a building. With the right tools applied, acoustic design can become an integral part of the architectural design process. The aim of this paper is to investigate the field of application that an acoustic simulation programme can have during an architectural...... the first phases in the architectural process and set out a reverse strategy for simulation programmes to do so - from developing acoustics from given spaces to developing spaces from given acoustics...

  9. Process development for the manufacture of an integrated dispenser cathode assembly using laser chemical vapor deposition

    Johnson, Ryan William

    2005-07-01

    Laser Chemical Vapor Deposition (LCVD) has been shown to have great potential for the manufacture of small, complex, two or three dimensional metal and ceramic parts. One of the most promising applications of the technology is in the fabrication of an integrated dispenser cathode assembly. This application requires the deposition of a boron nitride-molybdenum composite structure. In order to realize this structure, work was done to improve the control and understanding of the LCVD process and to determine experimental conditions conducive to the growth of the required materials. A series of carbon fiber and line deposition studies were used to characterize process-shape relationships and study the kinetics of carbon LCVD. These studies provided a foundation for the fabrication of the first high aspect ratio multi-layered LCVD wall structures. The kinetics studies enabled the formulation of an advanced computational model in the FLUENT CFD package for studying energy transport, mass and momentum transport, and species transport within a forced flow LCVD environment. The model was applied to two different material systems and used to quantify deposition rates and identify rate-limiting regimes. A computational thermal-structural model was also developed using the ANSYS software package to study the thermal stress state within an LCVD deposit during growth. Georgia Tech's LCVD system was modified and used to characterize both boron nitride and molybdenum deposition independently. The focus was on understanding the relations among process parameters and deposit shape. Boron nitride was deposited using a B3 N3H6-N2 mixture and growth was characterized by sporadic nucleation followed by rapid bulk growth. Molybdenum was deposited from the MoCl5-H2 system and showed slow, but stable growth. Each material was used to grow both fibers and lines. The fabrication of a boron nitride-molybdenum composite was also demonstrated. In sum, this work served to both advance the

  10. THE ORIGINS OF THE CASHLESS SOCIETY: CASH DISPENSERS, DIRECT TO ACCOUNT PAYMENTS AND THE DEVELOPMENT OF ON-LINE REAL-TIME NETWORKS, C.1965-1985

    Bernardo Bátiz-Lazo

    2014-07-01

    Full Text Available This article explores the technological choices made at the dawn of the massification of retail finance. We describe and analyze the early development of electronic banking and the foundations of the cashless society through the experiences of organizations with similar governance in two different competitive environments — Swedish and British savings banks. We document how the adoption of direct-to-account wage deposits and the subsequent deployment of networks of cash dispensers interacted with the adoption of on-line real-time (OLRT computing, and distinguish on- line and OLRT communication as distinct stages in the evolution of computer networks. We emphasize the role of middle managers in the selection of alternative technologies and show how delivering a cashless society proved more difficult than anticipated.

  11. Identification of risks associated with the prescribing and dispensing of oral anticancer medicines in Ireland.

    Hammond, Lisa

    2012-09-09

    Background Oral anticancer medicines (OAM) facilitate transfer of cancer care into the community, where safeguards developed in hospitals that control their prescribing, dispensing and administration may not exist. Objective To determine if the systems of prescribing and dispensing OAM in Ireland facilitate clinical verification of the prescription, thereby ensuring treatment is tailored and appropriate for the patient. Setting Randomly selected community pharmacies in Ireland and all Irish hospitals with cancer services. Method A questionnaire was sent to a random selection of Irish community pharmacists. A different questionnaire was sent to all Irish hospitals treating cancer patients. One hundred OAM prescriptions were retrospectively reviewed, to assess the information presented and the potential barriers to a community pharmacist performing a clinical verification of the prescription. Main outcome measure Community pharmacist survey: problems experienced when dispensing OAM and risk factors identified with the current system. Hospital pharmacist survey: proportion of hospitals that clinically verify prescriptions for parenteral versus oral anticancer medicines and associated policies. OAM prescription review: proportion of OAM prescriptions that contained sufficient information for a community pharmacist to clinically verify the prescription and safely dispense the medication. Results Sixty-four percent of community pharmacist respondents felt they did not have enough information available to them to safely dispense these prescriptions, and 74 % felt that patients are at risk with the current Irish system of prescribing and dispensing OAM. Irish hospitals do not have systems to ensure that all OAM prescriptions are clinically verified by a pharmacist. Seventeen different agents were prescribed on the prescriptions reviewed. The information provided to the community pharmacist would have allowed them to clinically verify 7 % of the OAM prescriptions

  12. Studies on acoustic modelling techniques for CANDU reactors

    This paper reviews the current technology being used to predict acoustic resonance in fluid-filled piping systems. The paper also reports on the analysis of a simple benchmark experiment that yielded some valuable insights and understanding into acoustic damping. A volumetric drag formula for the ABAQUS code is presented. Its application in experiments has yielded better results than previously obtained using a constant volumetric drag. (author). 24 refs., 1 tab., 12 figs

  13. Use of Acoustic Waves for Pulsating Water Jet Generation

    Foldyna, Josef

    1. Rijeka: InTech Open Access Publisher, 2011 - (Beghi, M.), s. 323-342 ISBN 978-953-307-572-3 R&D Projects: GA MŠk ED2.1.00/03.0082 Institutional research plan: CEZ:AV0Z30860518 Keywords : acoustic waves * pulsating water jet * technology Subject RIV: JQ - Machines ; Tools http://www.intechopen.com/books/acoustic-waves-from-microdevices-to-helioseismology

  14. ADVANCED ACOUSTIC EMISSION SOURCE LOCATION IN COMPLEX AIRCRAFT STRUCTURE

    Blaháček, Michal; Převorovský, Zdeněk

    Krakow: University of Technology Krakov, 2008 - (Kanji, O.), s. 172-177 ISBN 978-83-7242-478-5. [European Conference on Acoustic Emission Testing EWGAE /28./. Krakow (PL), 17.09.2008-19.09.2008] R&D Projects: GA ČR GA101/07/1518 Institutional research plan: CEZ:AV0Z20760514 Keywords : source location * aircraft structure * fuzzy Subject RIV: BI - Acoustics

  15. Wavefront Modulation and Subwavelength Diffractive Acoustics with an Acoustic Metasurface

    Xie, Yangbo; Wang, Wenqi; Chen, Huanyang; Konneker, Adam; Popa, Bogdan-Ioan; Cummer, Steven A.

    2014-01-01

    Metasurfaces are a family of novel wavefront shaping devices with planar profile and subwavelength thickness. Acoustic metasurfaces with ultralow profile yet extraordinary wave manipulating properties would be highly desirable for improving the performance of many acoustic wave-based applications. However, designing acoustic metasurfaces with similar functionality as their electromagnetic counterparts remains challenging with traditional metamaterial design approaches. Here we present a desig...

  16. ACOUSTICS IN ARCHITECTURAL DESIGN, AN ANNOTATED BIBLIOGRAPHY ON ARCHITECTURAL ACOUSTICS.

    DOELLE, LESLIE L.

    THE PURPOSE OF THIS ANNOTATED BIBLIOGRAPHY ON ARCHITECTURAL ACOUSTICS WAS--(1) TO COMPILE A CLASSIFIED BIBLIOGRAPHY, INCLUDING MOST OF THOSE PUBLICATIONS ON ARCHITECTURAL ACOUSTICS, PUBLISHED IN ENGLISH, FRENCH, AND GERMAN WHICH CAN SUPPLY A USEFUL AND UP-TO-DATE SOURCE OF INFORMATION FOR THOSE ENCOUNTERING ANY ARCHITECTURAL-ACOUSTIC DESIGN…

  17. Acoustic detection of pneumothorax

    Mansy, Hansen A.; Royston, Thomas J.; Balk, Robert A.; Sandler, Richard H.

    2003-04-01

    This study aims at investigating the feasibility of using low-frequency (pneumothorax detection were tested in dogs. In the first approach, broadband acoustic signals were introduced into the trachea during end-expiration and transmitted waves were measured at the chest surface. Pneumothorax was found to consistently decrease pulmonary acoustic transmission in the 200-1200-Hz frequency band, while less change was observed at lower frequencies (ppneumothorax states (pPneumothorax was found to be associated with a preferential reduction of sound amplitude in the 200- to 700-Hz range, and a decrease of sound amplitude variation (in the 300 to 600-Hz band) during the respiration cycle (pPneumothorax changed the frequency and decay rate of percussive sounds. These results imply that certain medical conditions may be reliably detected using appropriate acoustic measurements and analysis. [Work supported by NIH/NHLBI #R44HL61108.

  18. Seamount acoustic scattering

    Boehlert, George W.

    The cover of the March 1 issue of Eos showed a time series of acoustic scattering above Southeast Hancock Seamount (29°48‧N, 178°05‧E) on July 17-18, 1984. In a comment on that cover Martin Hovland (Eos, August 2, p. 760) argued that gas or “other far reaching causes” may be involved in the observed acoustic signals. He favors a hypothesis that acoustic scattering observed above a seeping pockmark in the North Sea is a combination of bubbles, stable microbubbles, and pelagic organisms and infers that this may be a more general phenomenon and indeed plays a role in the attraction of organisms to seamounts

  19. Practical acoustic emission testing

    2016-01-01

    This book is intended for non-destructive testing (NDT) technicians who want to learn practical acoustic emission testing based on level 1 of ISO 9712 (Non-destructive testing – Qualification and certification of personnel) criteria. The essential aspects of ISO/DIS 18436-6 (Condition monitoring and diagnostics of machines – Requirements for training and certification of personnel, Part 6: Acoustic Emission) are explained, and readers can deepen their understanding with the help of practice exercises. This work presents the guiding principles of acoustic emission measurement, signal processing, algorithms for source location, measurement devices, applicability of testing methods, and measurement cases to support not only researchers in this field but also and especially NDT technicians.

  20. Advanced Active Acoustics Lab (AAAL)

    Federal Laboratory Consortium — The Advanced Active Acoustics Lab (AAAL) is a state-of-the-art Undersea Warfare (USW) acoustic data analysis facility capable of both active and passive underwater...

  1. A New Wave of Acoustics.

    Beyer, Robert

    1981-01-01

    Surveys 50 years of acoustical studies by discussing selected topics including the ear, nonlinear representations, underwater sound, acoustical diagnostics, absorption, electrolytes, phonons, magnetic interaction, and superfluidity and the five sounds. (JN)

  2. A Century of Acoustic Metrology

    Rasmussen, Knud

    The development in acoustic measurement technique over the last century is reviewed with special emphasis on the metrological aspect.......The development in acoustic measurement technique over the last century is reviewed with special emphasis on the metrological aspect....

  3. Research and practice of intelligent scrub dispensing system in operation room under process reengineering%基于流程再造的手术室智能更衣系统的研究与实践

    凌蒙蒙; 张群瑜; 潘传迪

    2016-01-01

    目的:采用信息技术优化手术室更衣流程,改善手工流程的不足。方法:集成自助更衣机、CPU卡、电子储物柜、红外感应器等设备,开发手术室智能更衣软、硬件系统。结果:完成手术室智能更衣系统研发并投入正常运行,实现手术人员签到和签退、自动出衣、自动分配及回收储物柜、回收手术衣等功能。结论:手术室智能更衣系统对优化手术室更衣流程,缩短医务人员术前更衣时间,改善手术室环境,节约人力成本,提高服务效率具有积极的作用。%Objective: To optimize scrub dispensing process in operating room and replace previous manual process by information technology. Methods: Integrate self-service scrub dispensing machine, CPU card, electronic lockers, infrared sensors and other equipment were used to develop intelligent scrub dispensing hardware and software system in operation room. Results: The system is developed and put into normal operation. The intelligent scrub dispensing system achieves automatic operation personnel sign-in and sign-out, self serving surgical gowns, automatic allocation and locker reuse, self-recycle of dirty surgical gowns and other functions. Conclusions: The intelligent scrub dispensing system in operation room is a positive effect on optimizing the scrub dispensing process in operating room, shorting the time of medical personnel to change surgical gowns, improving the environment of the operation room, reducing labor costs, improving the service efficiency.

  4. Technology

    Xu Jing

    2016-01-01

    Full Text Available The traditional answer card reading method using OMR (Optical Mark Reader, most commonly, OMR special card special use, less versatile, high cost, aiming at the existing problems proposed a method based on pattern recognition of the answer card identification method. Using the method based on Line Segment Detector to detect the tilt of the image, the existence of tilt image rotation correction, and eventually achieve positioning and detection of answers to the answer sheet .Pattern recognition technology for automatic reading, high accuracy, detect faster

  5. Acoustic GW detectors in the 2010 timeframe

    I consider the spectral sensitivities and bandwidths, in the standard quantum limit, of the narrowband spherical detectors, which would evolve from the present bar detectors and the wideband novel 'dual' detectors that have been proposed recently. If appropriate advanced fabrication and read-out technologies are developed, both kinds of GW acoustic detectors would play a relevant role in the near-kHz frequency region

  6. Strong acoustic wave action

    Gokhberg, M. B.

    1983-07-01

    Experiments devoted to acoustic action on the atmosphere-magnetosphere-ionosphere system using ground based strong explosions are reviewed. The propagation of acoustic waves was observed by ground observations over 2000 km in horizontal direction and to an altitude of 200 km. Magnetic variations up to 100 nT were detected by ARIEL-3 satellite near the epicenter of the explosion connected with the formation of strong field aligned currents in the magnetosphere. The enhancement of VLF emission at 800 km altitude is observed.

  7. Structural Acoustics and Vibrations

    Chaigne, Antoine

    This structural chapter is devoted to vibrations of structures and to their coupling with the acoustic field. Depending on the context, the radiated sound can be judged as desirable, as is mostly the case for musical instruments, or undesirable, like noise generated by machinery. In architectural acoustics, one main goal is to limit the transmission of sound through walls. In the automobile industry, the engineers have to control the noise generated inside and outside the passenger compartment. This can be achieved by means of passive or active damping. In general, there is a strong need for quieter products and better sound quality generated by the structures in our daily environment.

  8. Densitometry By Acoustic Levitation

    Trinh, Eugene H.

    1989-01-01

    "Static" and "dynamic" methods developed for measuring mass density of acoustically levitated solid particle or liquid drop. "Static" method, unknown density of sample found by comparison with another sample of known density. "Dynamic" method practiced with or without gravitational field. Advantages over conventional density-measuring techniques: sample does not have to make contact with container or other solid surface, size and shape of samples do not affect measurement significantly, sound field does not have to be know in detail, and sample can be smaller than microliter. Detailed knowledge of acoustic field not necessary.

  9. Noncontact Acoustic Manipulation in Air

    Kozuka, Teruyuki; Yasui, Kyuichi; Tuziuti, Toru; Towata, Atsuya; Iida, Yasuo

    2007-07-01

    A noncontact manipulation technique is useful for micromachine technology, biotechnology, and new materials processing. In this paper, we describe an advanced manipulation technique for transporting small objects in air. A standing wave field was generated by two sound beams crossing each other generated by bolted Langevin transducers. Expanded polystyrene particles were trapped at the nodes of the sound pressure in the standing wave field. The position of a trapped particle was shifted by changing the phase difference between the two sound beams. When the trapped particle is transported, it spatially oscillate periodically in a direction perpendicular to that of particle transportation. The numerical calculation of an acoustic field revealed that it is caused by the reflection of an ultrasonic wave at each transducer surface.

  10. Microbiological Quality of Drinking Water from Dispensers in Roadside Restaurants of Bangladesh

    Islam, M. A.; Akter, S.; M. Moniruzzaman; Z. Mia

    2011-01-01

    The microbiological status of water from dispensers in different roadside restaurants of Dhaka city and Savar area was analyzed in this study. Seven samples from Dhaka and 8 samples of Savar were checked. The heterotrophic plate count was in a range of 1.0x103 CFU mL-1 to 2.0x104 CFU mL-1 (from new bottles), 1.0x103 to 1.5x104 CFU mL-1 (after dispensation), and 1.5x103 CFU mL-1 to 1.0x105 CFU mL-1 (from serving glass). In several of the samples, the heterotrophic plate count was higher than ...

  11. Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream

    Jacobson, Stephen C [Knoxville, TN; Ramsey, J Michael [Knoxville, TN

    2008-09-09

    A microfluidic device and method for forming and dispensing minute volume segments of a material are described. In accordance with the present invention, a microfluidic device and method are provided for spatially confining the material in a focusing element. The device is also adapted for segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.

  12. Development of alloy-film coated dispenser cathode for terahertz vacuum electron devices application

    High power terahertz vacuum electron devices demand high current density and uniform emission dispenser cathode. It was found that the coating of noble metals e.g., Os, Ir, and Re on the surface of tungsten dispenser cathodes enhances the emission capabilities and uniformity. Hence metal coated cathode might be the best candidate for terahertz devices applications. In this study, ternary-alloy-film cathode (2Os:2Re:1 W) and Os coated cathode have been developed and the results are presented. The cathodes made out of this alloy coating showed 1.5 times higher emission and 0.02 eV emission uniformity as compared to those of simply Os coated cathodes which can be used in terahertz devices application.

  13. Model for the evaluation of drug-dispensing services in primary health care

    Sartor, Vanessa de Bona; de Freitas, Sergio Fernando Torres

    2014-01-01

    OBJECTIVE To develop a model for evaluating the efficacy of drug-dispensing service in primary health care. METHODS An efficacy criterion was adopted to determine the level of achievement of the service objectives. The evaluation model was developed on the basis of a literature search and discussions with experts. The applicability test of the model was conducted in 15 primary health care units in the city of Florianópolis, state of Santa Catarina, in 2010, and data were recorded in structured and pretested questionnaires. RESULTS The model developed was evaluated using five dimensions of analysis for analysis. The model was suitable for evaluating service efficacy and helped to identify the critical points of each service dimension. CONCLUSIONS Adaptations to the data collection technique may be required to adjust for the reality and needs of each situation. The evaluation of the drug-dispensing service should promote adequate access to medications supplied through the public health system. PMID:25372174

  14. Emission characteristics of dispenser cathodes with a fine-grained tungsten top layer

    Kimura, S.; Higuchi, T.; Ouchi, Y.; Uda, E.; Nakamura, O.; Sudo, T.; Koyama, K.

    1997-02-01

    In order to improve the emission stability of the Ir-coated dispenser cathode under ion bombardment, a fine-grained tungsten top layer was applied on the substrate porous tungsten plug before Ir coating. The emission characteristics were studied after being assembled in a CRT gun. Cathode current was measured under pulse operation in a range of 0.1-9% duty. Remarkable anti-ion bombardment characteristics were observed over the range of 1-6% duty. The improved cathode showed 1.5 times higher emission current than that of a conventional Ir-coated dispenser cathode at 4% duty. AES analysis showed that the recovering rates of surface Ba and O atoms after ion bombardment were 2.5 times higher. From these results it is confirmed that the Ir coated cathode with a fine-grained tungsten top layer is provided with a good tolerance against the ion bombardment.

  15. The way to reduce electrical charge of a droplet dispensed from a pipette tip

    Choi, Dongwhi; Im, Do Jin; Kim, Dong Sung

    2013-01-01

    Recently, our group reported that an any aqueous droplet dispensed from a pipette tip has considerable amount of electrical charge. This natural electrical charge of a droplet could cause undesired, unfamiliar experimental results. Since the origin of the charge of a droplet is related to the pipette tip material, we modified the inside material of the pipette tip with poly(dimethylsiloxane)-graphene nanocomposites. The droplets dispensed from the modified pipette tip has lower electrical charge than that from the common pipette tip. We compare the experimental results with the droplets from common pipette tip and modified pipette tip. This fluid dynamics video includes the principle of the spontaneous electrification of the droplet and the results of the droplet in oil experiments.

  16. Integration of dispenser-printed ultra-low-voltage thermoelectric and energy storage devices

    This paper reports on an integrated energy harvesting prototype that consists of dispenser-printed thermoelectric energy harvesting and electrochemical energy storage devices. Parallel-connected thermoelectric devices with low internal resistances were designed, fabricated and characterized. The use of a commercially available dc-to-dc converter was explored to step-up a 27.1 mV input voltage from a printed thermoelectric device to a regulated 2.34 V output at a maximum of 34% conversion efficiency. The regulated power succeeds in charging dispenser-printed, zinc-based micro-batteries with charging efficiencies of up to 67%. The prototype presented in this work demonstrates the feasibility of deploying a printable, cost-effective and perpetual power solution for practical wireless sensor network applications. (paper)

  17. Development of alloy-film coated dispenser cathode for terahertz vacuum electron devices application

    Barik, R. K.; Bera, A.; Raju, R. S.; Tanwar, A. K.; Baek, I. K.; Min, S. H.; Kwon, O. J.; Sattorov, M. A.; Lee, K. W.; Park, G.-S.

    2013-07-01

    High power terahertz vacuum electron devices demand high current density and uniform emission dispenser cathode. It was found that the coating of noble metals e.g., Os, Ir, and Re on the surface of tungsten dispenser cathodes enhances the emission capabilities and uniformity. Hence metal coated cathode might be the best candidate for terahertz devices applications. In this study, ternary-alloy-film cathode (2Os:2Re:1 W) and Os coated cathode have been developed and the results are presented. The cathodes made out of this alloy coating showed 1.5 times higher emission and 0.02 eV emission uniformity as compared to those of simply Os coated cathodes which can be used in terahertz devices application.

  18. Development of suitable potting material for dispenser cathodes of a high power microwave tube

    Pal, Kalyan S.; Ghosh, Sumana; Dandapat, Nandadulal [Bio-Ceramics and Coating Division, CSIR - Central Glass and Ceramic Research Institute, 196, Raja S.C. Mullick Road, Kolkata 700 032, West Bengal (India); Datta, Someswar, E-mail: sdatta@cgcri.res.in [Bio-Ceramics and Coating Division, CSIR - Central Glass and Ceramic Research Institute, 196, Raja S.C. Mullick Road, Kolkata 700 032, West Bengal (India); Basu, Debabrata [Bio-Ceramics and Coating Division, CSIR - Central Glass and Ceramic Research Institute, 196, Raja S.C. Mullick Road, Kolkata 700 032, West Bengal (India); Raju, R.S. [Microwave Tubes Division, CSIR - Central Electronics Engineering Research Institute, Pilani 333031, Rajasthan (India)

    2012-02-15

    Highlights: Black-Right-Pointing-Pointer Potting material. Black-Right-Pointing-Pointer Doped alumina. Black-Right-Pointing-Pointer Non-shrinkable. Black-Right-Pointing-Pointer Dispenser cathode. Black-Right-Pointing-Pointer Microwave tube. - Abstract: The present study aims to develop suitable advanced potting material for modern high performance dispenser cathodes for high power microwave tube through refinement of the alumina microstructure by using suitable dopant. Calcium oxide was selected as a dopant material and the resultant materials were characterized by X-ray diffraction studies and the microstructure monitored by SEM study and EDX analysis. The shrinkage, thermal and electrical properties of the resultant material was evaluated to establish its suitability to function as an advanced potting material.

  19. The quantum efficiency of dispenser photocathodes: Comparison of theory to experiment

    Jensen, Kevin L.; Feldman, Donald W.; O'Shea, Patrick G.

    2004-11-01

    The quantum efficiency (QE) characteristics of commercially available dispenser cathodes were measured, giving QEs of (for Scandate) 6.5×10-5, 2.0×10-4, and 8.0×10-4, and (for M-type) 3.0×10-4, 1.4×10-3, and 2.6×10-3, for wavelengths of 532, 355, and 266nm, respectively, corresponding to harmonics of an Nd:YAG laser. A time-dependent photoemission model was developed to analyze the data, as well as dispenser and metal photocathode data in the literature, and quantitatively good agreement is found, demonstrating the utility of the code as a predictive estimator of performance.

  20. Towards a Robust, Efficient Dispenser Photocathode: the Effect of Recesiation on Quantum Efficiency

    Future electron accelerators and Free Electron Lasers (FELs) require high brightness electron sources; photocathodes for such devices are challenged to maintain long life and high electron emission efficiency (high quantum efficiency, or QE). The UMD dispenser photocathode design addresses this tradeoff of robustness and QE. In such a dispenser, a cesium-based surface layer is deposited on a porous substrate. The surface layer can be replenished from a subsurface cesium reservoir under gentle heating, allowing cesium to diffuse controllably to the surface and providing demonstrably more robust photocathodes. In support of the premise that recesiation is able to restore contaminated photocathodes, we here report controlled contamination of cesium-based surface layers with subsequent recesiation and the resulting effect on QE. Contaminant gases investigated include examples known from the vacuum environment of typical electron guns.

  1. Measurement of Low Workfunction Cesiated Metals for Use in Dispenser Photocathodes

    Moody, N A; O'Shea, P G

    2005-01-01

    Photoinjector performance is a limiting factor in the continued development of high powered FELs. Presently available photocathodes have limited efficiency and short lifetime in an RF-gun environment, due to contamination or evaporation of a photosensitive surface layer. An ideal photocathode should have high efficiency at visible wavelengths, long lifetime in practical vacuum environments, and prompt emission. High efficiency cathodes typically have limited lifetime, and the needs of the photocathode are generally at odds with those of the drive laser. A potential solution is the low work function dispenser cathode, where short lifetimes are overcome by periodic in situ regeneration that restores the photosensitive surface layer, analogous to methods used in the power tube industry. This work reports on the fabrication techniques and performance of cesiated metal photocathodes and cesiated dispenser cathodes, with a focus on understanding and improving quantum efficiency and lifetime, analyzing issues of emi...

  2. On-chip liquid storage and dispensing for lab-on-a-chip applications

    This work presents novel components for on-chip storage and dispensing inside a lab-on-a-chip (LOC) for applications in immunoassay point-of-care testing (POCT), where incubation and washing steps are essential. It involves easy-to-use on-chip solutions for the sequential thermo-hydraulic actuation of liquids. The novel concept of combining the use of a rubber plug, both as a non-return valve cap and as a liquid injection interface of a sealed reservoir, allows simple filling of a sterilized cavity, as well as the storage and dispensing of reagent and washing buffer liquids. Segmenting the flow with air spacers enables effective rinsing and the use of small volumes of on-chip stored liquids. The chip uses low-resistance resistors as heaters in the paraffin actuator, providing the low-voltage actuation that is preferred for handheld battery driven instruments

  3. Enhanced acoustic sensing through wave compression and pressure amplification in anisotropic metamaterials.

    Chen, Yongyao; Liu, Haijun; Reilly, Michael; Bae, Hyungdae; Yu, Miao

    2014-01-01

    Acoustic sensors play an important role in many areas, such as homeland security, navigation, communication, health care and industry. However, the fundamental pressure detection limit hinders the performance of current acoustic sensing technologies. Here, through analytical, numerical and experimental studies, we show that anisotropic acoustic metamaterials can be designed to have strong wave compression effect that renders direct amplification of pressure fields in metamaterials. This enables a sensing mechanism that can help overcome the detection limit of conventional acoustic sensing systems. We further demonstrate a metamaterial-enhanced acoustic sensing system that achieves more than 20 dB signal-to-noise enhancement (over an order of magnitude enhancement in detection limit). With this system, weak acoustic pulse signals overwhelmed by the noise are successfully recovered. This work opens up new vistas for the development of metamaterial-based acoustic sensors with improved performance and functionalities that are highly desirable for many applications. PMID:25316410

  4. Acoustic subwavelength imaging of subsurface objects with acoustic resonant metalens

    Cheng, Ying; Liu, XiaoJun, E-mail: liuxiaojun@nju.edu.cn [Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210093 (China); State Key Laboratory of Acoustics, Institute of Acoustics, Chinese Academy of Sciences, Beijing 100190 (China); Zhou, Chen; Wei, Qi; Wu, DaJian [Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210093 (China)

    2013-11-25

    Early research into acoustic metamaterials has shown the possibility of achieving subwavelength near-field acoustic imaging. However, a major restriction of acoustic metamaterials is that the imaging objects must be placed in close vicinity of the devices. Here, we present an approach for acoustic imaging of subsurface objects far below the diffraction limit. An acoustic metalens made of holey-structured metamaterials is used to magnify evanescent waves, which can rebuild an image at the central plane. Without changing the physical structure of the metalens, our proposed approach can image objects located at certain distances from the input surface, which provides subsurface signatures of the objects with subwavelength spatial resolution.

  5. Acoustic subwavelength imaging of subsurface objects with acoustic resonant metalens

    Early research into acoustic metamaterials has shown the possibility of achieving subwavelength near-field acoustic imaging. However, a major restriction of acoustic metamaterials is that the imaging objects must be placed in close vicinity of the devices. Here, we present an approach for acoustic imaging of subsurface objects far below the diffraction limit. An acoustic metalens made of holey-structured metamaterials is used to magnify evanescent waves, which can rebuild an image at the central plane. Without changing the physical structure of the metalens, our proposed approach can image objects located at certain distances from the input surface, which provides subsurface signatures of the objects with subwavelength spatial resolution

  6. ACOUSTIC RADIATION ENERGY AT A VARIATION OF THE COMPOSITE MECHANICAL DESTRUCTION AREA

    Sergii Filonenko

    2016-06-01

    Full Text Available Purpose: The technological parameters of composite materials machining and also cutting tool state determine deforming and destruction of their surface layers conditions. Change of this conditions results to appearance of miscellaneous defects, loss of quality and produced items reliability. Therefore, optimization, control, diagnosis and monitoring of composite materials machining technological parameters are directed on obtaining the items given quality. For the solution of these problems tasks carry out researches of technological processes with usage of different methods. One of such methods is the acoustic emission method. Methods: The simulation and analysis of acoustic radiation energy parameters is carried out at change of composite material machining depth for prevailing mechanical destruction its surface layer. Results: We showed that to composite material machining the acoustic radiation energy has continuous nature. The ascending of composite material machining depth results to increase of acoustic emission statistical energy parameters. The regularity of acoustic emission energy parameters change are obtained and described. Is showed, that acoustic radiation most sensing parameter is the acoustic emission signals energy average level dispersion. Discussion: The outcomes researches demonstrate regularity influencing of composite material machining depth on acoustic emission energy parameters. Thus the analysis of acoustic emission signals energy average level dispersion can be used at mining methods of diagnostic, monitoring and control of composite materials machining technological parameters.

  7. An Overview of Acoustic Telemetry

    Drumheller, D.S.

    1992-03-24

    Acoustic telemetry has been a dream of the drilling industry for the past 50 years. It offers the promise of data rates which are one-hundred times greater than existing technology. Such a system would open the door to true logging-while-drilling technology and bring enormous profits to its developers. The oil and gas industry has led in most of the attempts to develop this type of telemetry system; however, very substantial efforts have also been made through government sponsored work in the geothermal industry. None of these previous attempts have lead to a commercial telemetry system. Conceptually, the problem looks easy. The basic idea is to produce an encoded sound wave at the bottom of the well, let it propagate up the steel drillpipe, and extract the data from the signal at the surface. Unfortunately, substantial difficulties arise. The first difficult problem is to produce the sound wave. Since the most promising transmission wavelengths are about 20 feet, normal transducer efficiencies are quite low. Compounding this problem is the structural complexity of the bottomhole assembly and drillstring. For example, the acoustic impedance of the drillstring changes every 30 feet and produces an unusual scattering pattern in the acoustic transmission. This scattering pattern causes distortion of the signal and is often confused with signal attenuation. These problems are not intractable. Recent work has demonstrated that broad frequency bands exist which are capable of transmitting data at rates up to 100 bits per second. Our work has also identified the mechanism which is responsible for the observed anomalies in the patterns of signal attenuation. Furthermore in the past few years a body of experience has been developed in designing more efficient transducers for application to metal Waveguides. The direction of future work is clear. New transducer designs which are more efficient and compatible with existing downhole power supplies need to be built and tested

  8. Elderly drug utilization in the community assessed through pharmacy dispensing data

    Martínez Sánchez, Alina de las Mercedes

    2013-01-01

    People of 65 years and above now comprise a greater share of the world's population than ever before, and this proportion will increase during the 21st century. In Spain, between 55 and 90% of the elderly consume a drug. This study characterizes the use of drugs by elderly through dispensing data at the community pharmacy. This study was conducted at a community pharmacy in Madrid, Spain in 2011. A retrospective and descriptive consumption study was conducted using computerized ph...

  9. Influence of the Separation of Prescription and Dispensation of Medicine on Its Cost in Japanese Prefectures

    Yokoi, Masayuki; Tashiro, Takao

    2014-01-01

    We studied how the separation of dispensing and prescribing of medicines between pharmacies and clinics (the “separation system”) can reduce internal medicine costs. To do so, we obtained publicly available data by searching electronic databases and official web pages of the Japanese government and non-profit public service corporations on the Internet. For Japanese medical institutions, participation in the separation system is optional. Consequently, the expansion rate of the separation sys...

  10. Prescription, Dispensation, and Generic Medicine Replacement Ratios: Influence on Japanese Medicine Costs

    Yokoi, Masayuki; Tashiro, Takao

    2015-01-01

    This study used publicly available data to examine the effect of the separation of dispensing and prescribing medicines between pharmacists in pharmacies and doctors in medical institutions (the separation system) and the generic medicine replacement ratio on the cost of various medicines in Japanese prefectures. For Japanese medical institutions, participation in the separation system is optional. Consequently, the expansion rate of the separation system for each administrative district is h...

  11. Influence of pharmacists' opinions on their dispensing medicines without requirement of a doctor's prescription

    Francisco Caamaño; Manuel Tomé-Otero; Bahi Takkouche; Juan Jesús Gestal-Otero

    2005-01-01

    Objective: To assess the influence of pharmacists' opinions on their dispensing medicines with a «medical prescription only» label without requiring a doctor's prescription. Methods: We performed a cross-sectional study of 166 community pharmacies in northwest Spain. The opinions of pharmacists on the following were collected as independent variables through personal interview: a) physicians' prescribing practices; b) the pharmacist's qualifications to prescribe; c) the responsibility of the ...

  12. Evaluation of Pharmacists' Services for Dispensing Emergency Contraceptive Pills in Delhi, India: A Mystery Shopper Study

    Saxena, Pikee; Mishra, Archana; Nigam, Aruna

    2016-01-01

    Background: Although emergency contraceptive pills are available over the counter, the quality of consultation, including key areas of contraceptive counseling and prevention of sexually transmitted infections (STI), has not been well documented. Objective: To evaluate actual pharmacist services while dispensing emergency contraception through a mystery shopper technique. Material and Methods: This cross-sectional study was conducted in 81 pharmacies situated in Delhi by 4 trained mystery sho...

  13. Evaluation of pharmacists' services for dispensing emergency contraceptive pills in Delhi, India: A mystery shopper study

    Pikee Saxena; Archana Mishra; Aruna Nigam

    2016-01-01

    Background: Although emergency contraceptive pills are available over the counter, the quality of consultation, including key areas of contraceptive counseling and prevention of sexually transmitted infections (STI), has not been well documented. Objective: To evaluate actual pharmacist services while dispensing emergency contraception through a mystery shopper technique. Material and Methods: This cross-sectional study was conducted in 81 pharmacies situated in Delhi by 4 trained mystery sho...

  14. Experience with a combined pneumatic system for the dispensing and conveying of pulverized coal

    Baumeister, W.

    1981-05-01

    Operating experience gained with the 'Carbodos' pneumatic feed regulating system for pulverized coal is reported. Basing himself on a short description of the installation and system, the author indicates the principal changes to the completed storage and dispensing plant for pulverized lignite. Experience has shown that it is possible, with the 'Carbodos' system, to operate a 3500 t/day rotary kiln with 100 per cent pulverized lignite fuel.

  15. Oxygen transport in the internal xenon plasma of a dispenser hollow cathode

    Capece, Angela M.; Polk, James E.; Mikellides, Ioannis G.; Shepherd, Joseph E.

    2014-01-01

    Reactive gases such as oxygen and water vapor modify the surface morphology of BaO dispenser cathodes and degrade the electron emission properties. For vacuum cathodes operating at fixed temperature, the emission current drops rapidly when oxygen adsorbs on top of the low work function surface. Previous experiments have shown that plasma cathodes are more resistant to oxygen poisoning and can operate with O_2 partial pressures one to two orders of magnitude higher than vacuum cathodes before ...

  16. Understanding of pictograms from the United States Pharmacopeia Dispensing Information (USP-DI) among elderly Brazilians

    Barros IMC; Alcântara TS; Mesquita AR; Bispo ML; Rocha CE; Moreira VP; Lyra Junior DP

    2014-01-01

    Izadora MC Barros, Thaciana S Alcântara, Alessandra R Mesquita, Monica L Bispo, Chiara E Rocha, Vagner Porto Moreira, Divaldo P Lyra Junior Laboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Brazil Objective: To assess the understanding and cultural acceptability of the United States Pharmacopeia Dispensing Information (USP-DI) in a group of elderly ...

  17. Study and characterization of dispenser cathode of 10 MeV Linac

    A dispenser cathode of pressed and sintered Ba-Ni powder is used as electron source in electron linac having 10 MeV beam energy and 10 kW beam power at RRCAT. This linac is planned for development of agricultural radiation processing facility. In this e-linac a triode type electron gun is used. This paper describes the cathode behavioural model during operation with addition of sparkle on materials characterization of diminished emission cathode surface. (author)

  18. Modelling and Forecasting Branded and Generic Pharmaceutical Life Cycles: Assessment of the Number of Dispensed Units

    S. Buxton; Kostas Nikolopoulos; Khammash, M.; Stern, P.

    2015-01-01

    In this paper, modelling and forecasting pharmaceutical life cycles are investigated, specifically at the time of patent expiry when the generic form of the product could be introduced to the market, while the branded form is still available for prescription. Assessing the number of dispensed units of branded and generic forms of pharmaceuticals is increasingly important due to the irrelatively large market value in the United Kingdom and the limited number of new ÔblockbusterÕ branded drugs....

  19. Measuring and prediction mediction adherence using dispensing data and patient beliefs

    Geers, H.C.J.

    2012-01-01

    Introduction Medication adherence can be subdivided into drug initiation, drug taking compliance and (non)persistence. Objective of this thesis was to (1) investigate whether measurement methods and reporting of adherence influenced outcomes, (2) predict poor drug taking compliance and nonpersistence from historical dispensing data and patient beliefs. Methods To answer objective (1) a systematic review and meta-(regression)-analysis was done to investigate whether reporting of adherence, mea...

  20. Automated dose dispensing service for primary healthcare patients: a systematic review

    SinnemÀki, Juha; Sihvo, Sinikka; IsojÀrvi, Jaana; Blom, Marja; Airaksinen, Marja; MÀntylÀ, Antti

    2013-01-01

    Background An automated dose dispensing (ADD) service has been implemented in primary healthcare in some European countries. In this service, regularly used medicines are machine-packed into unit-dose bags for each time of administration. The aim of this study is to review the evidence for ADD’s influence on the appropriateness of medication use, medication safety, and costs in primary healthcare. Methods A literature search was performed in April 2012 in the most relevant databases (n = 10),...

  1. Home studio acoustic treatments on a budget

    Haverstick, Gavin A.

    2003-04-01

    Digital technology in the recording industry has evolved and expanded, allowing it to be widely available to the public at a significantly lower cost than in previous years. Due to this fact, numerous home studios are either being built inside or converted from bedrooms, dens, and basements. Hobbyists and part-time musicians that typically do not have the advantage of a large recording budget operate the majority of these home studios. Along with digital equipment, acoustic treatment has become more affordable over the years giving many musicians the ability to write, record, and produce an entire album in the comfort of their own home without having to sacrifice acoustical quality along the way. Three separate case studies were conducted on rooms with various sizes, applications, and budgets. Acoustical treatment such as absorption, diffusion, and bass trapping were implemented to reduce the effects of issues such as flutter echo, excessive reverberation, and bass build-up among others. Reactions and subjective comments from each individual studio owner were gathered and assessed to determine how effective home studios can be on a personal and professional level if accurately treated acoustically.

  2. “Adverse Drug Reaction Reporting” Knowledge, Attitude and Practices of Community Pharmacy Dispensers in Dar es salaam, Tanzania

    Shimwela, Grace Mng’ong’o

    2011-01-01

    Under reporting of adverse drug reactions (ADRs) by healthcare personnel is a common problem of many Pharmacovigilence programs. Lack of involvement of healthcare professionals such as pharmacists and other pharmaceutical dispensers has been cited as one of the reasons for under reporting. Pharmaceutical dispensers in the community pharmacies are in unique position by virtue of their training and profession to observe ADRs in patients, as many patients often try to avoid doctor consultation f...

  3. Dispensing of high concentration Ag nano-particles ink for ultra-low resistivity paper-based writing electronics

    Fuliang Wang; Peng Mao; Hu He

    2016-01-01

    Paper-based writing electronics has received a lot of interest recently due to its potential applications in flexible electronics. To obtain ultra-low resistivity paper-based writing electronics, we developed a kind of ink with high concentration of Ag Nano-particles (up to 80 wt%), as well as a related dispensing writing system consisting an air compressor machine and a dispenser. Additionally, we also demonstrated the writability and practical application of our proposed ink and writing sys...

  4. Raw Milk Hygiene at Local Markets and Automatic Milk Dispenser Machines

    Gheorghe Şteţca

    2014-11-01

    Full Text Available In Romania, direct sales of raw milk to the final consumer is developed based on the local regulations. These are in accordance to European Regulation that must meet some quality requirements for the total number of germs, somatic cells, without antibiotics, coming from healthy animals who did not suffer from diseases that can be transmitted to humans through milk. Raw milk is sold in Romania in local markets and by automatic milk dispenser machines. Based on these regulations, a study regarding the quality and security to human health of raw milk was conducted on the commercialized milk in local markets and automatic milk dispensers. During May-June 2014 samples of raw milk were collected from Cluj-Napoca local markets and automatic milk dispensers. All samples were kept to refrigeration conditions until the moment of analyze which took place at the sampling day. The following parameters were taken into account: fat content, protein, casein, lactose, nonfat dry matter, pH, milk freezing point, added water, antibiotics residues, milk urea, number of germ cells and somatic cells. All obtained results were verified by the validated methods applied. Our research can be forward conducted in order to verify the hygiene and composition of milk from the whole dairy chain. 

  5. Measurement of microbic contamination rate in the dispensing process making suspension of barium sulfate powder

    The purpose of this study is to investigate the contamination rate of barium sulfate suspension made in the exposed state in usual circumstances. This study was performed in four university hospital using the contrast media by barium sulfate powder. The specimen were detected at dispensing water, agitator and mixing tank. We also classified the suspension into general bacteria, mycete and Bacillus coli infection. The tap water were used to dispense water in the all hospitals. Bacillus coli were not detected in the all. General bacteria and mycete were not detected in the one specimen, but detected in two specimen over defined value. In the contamination rate of agitator, mixing tank, and the manufactured. Bacillus coli were not detected in all. However, general bacteria and mycete were detected too numberous to count. In conclusion, the refined water must be used in dispensing water in manufacturing suspension. The disinfectant is also used in washing the agitator and mixing tank for sterilization. Hand washing is indispensable to manufacturing suspension for preventing from infection

  6. Acoustic Emission Stethoscope - Measurements with Acoustic Emission on Wind Turbines

    Krystof Kryniski [AaF Infrastructure, Stockholm (Sweden)

    2013-02-15

    A remote ultrasonic stethoscope, designed on mobile devices to help a maintenance team in diagnosing drive train problems, has been demonstrated. By implementing an acoustic emission technology, the operating conditions of wind turbines have been assessed by trending techniques and ultrasonic acoustic emission converted into audible sound. The new approach has been developed and tested and compared to other monitoring techniques. Acoustic emission has generally been shown to provide a number of advantages over vibration and shock pulse methods because the system is operating in a substantially higher frequency range (100 kHz) and therefore it is more immune to operation of surrounding machines and components. Quick attenuation of ultrasonic propagation waves in the drive-train structure helps to pin-point the origin of any fault as the signals are sharper and more pronounced. Further, with the intensity measurements a direction of the source of ultrasonic energy can be identified. Using a high frequency thus makes the method suitable for measuring local effects and to determine local defects since the disturbing signals from other parts are damped. Recently developed programmable sensors capable of processing signals onboard, producing quality outputs with extremely low noise-to-signal ratio, have been used. It is discussed how the new approach can lower the cost of a wind-turbine monitoring system, while at the same time making it simple and more reliable, see Appendix A. The method has been tested on rotating parts of wind-turbines, including traditionally difficult areas such as low speed main bearings and planetary gearboxes. The method developed in the project was designed to see physical processes such as friction, impacts and metal removal, occurring when machinery degrades, can be detected and notified with the developed notification system. Apart from reporting the status and displaying the changes of the pre-defined parameters or symptoms, the system has

  7. Underwater Acoustic Networking Techniques

    Otnes, Roald; Casari, Paolo; Goetz, Michael; Husøy, Thor; Nissen, Ivor; Rimstad, Knut; van Walree, Paul; Zorzi, Michele

    2012-01-01

    This literature study presents an overview of underwater acoustic networking. It provides a background and describes the state of the art of all networking facets that are relevant for underwater applications. This report serves both as an introduction to the subject and as a summary of existing protocols, providing support and inspiration for the development of network architectures.

  8. COMBUSTION ACOUSTICS DIAGNOSTICS

    This is an Exploratory Research Project that was awarded by APPCD for research on developing an acoustic flame condition monitor. It will involve a bench scale experiment of 4-6 weeks duration to record adjacent audible energy of a Bunsen burner. The experiment will require a d...

  9. Acoustic Signals and Systems

    present topics on signal processing which are important in a specific area of acoustics. These will be of interest to specialists in these areas because they will be presented from their technical perspective, rather than a generic engineering approach to signal processing. Non-specialists, or specialists...

  10. Pediatric burns due to hot water from water dispenser: a neglected issue that should be highly concerned

    MA Bing; XI Hui-jun; WANG Jia-lin; YAN Ying; TANG Hong-tai; ZHU Shi-hui; L(U) Kai-yang; XIA Zhao-fan

    2012-01-01

    Background More and more Chinese drink hot water from water dispensers while many children were scalded due to this change.The present study aimed to propose a feasible strategy for prevention.Methods A retrospective study was conducted for all water dispensers related pediatric burns admitted to Changhai Hospital from January 2005 to December 2009.Results The number of new cases and incidences of pediatric burns due to hot water from water dispensers was significantly increasing year after year.In the total 238 involved cases,175 cases happened on males and 78.9% were at the age of 1-4 years.The burn areas were mainly located in upper extremities.All water dispensers in the surveyed families had no isolate protection devices and 85.2% of their locations were easy for children to reach.Nearly half of the children were in the same room with their guardians when injured.Total 196 burned children were playing the taps of water dispensers before injured,unfortunately,80.6% of them have not been stopped until burned.Conclusion As the kind of bums is quite serious and with bad outcome,some recommendations should be followed,such as buying water dispensers with protection devices,keeping children from touching them and so on.

  11. Inquiry and practice of acoustic technology of the theater at home and abroad%近现代中外剧场声学技术探索与实践

    黄帅; 刘燕彬

    2014-01-01

    以建筑声学的探索轨迹为线索,详细列举了近现代国内外著名剧场建设实际案例,介绍了建筑声学的发展状况,指出邀请专业的声学团队参与剧场的建筑设计是剧场建筑的发展趋势。%Taking the architectural acoustics inquiry as the routine,the paper lists famous theater construction practice at home and abroad,intro-duces architectural acoustic development conditions,and points out that inviting professional acoustic team to participating theater building design is the development trend of theater building.

  12. National Television of Chile--New headquarters building acoustic projects

    Huaquin, Mario

    2002-11-01

    In the last 15 years TV stations in Chile have been incorporating in their facilities architectural acoustic and noise control approaches. This has been necessary as much for the technological advance, as for the necessity to achieve a better quality of sound that the listeners receive. In 1998, the National Television of Chile, with the sponsorship of the College of Architects of Chile, requested preliminary architectural designs in order to enlarge and to renovate its headquarters buildings in Santiago, Chile in stages. The Acoustic Project has been developed in an integral way, with three fundamental disciplines: noise and noise control; Machine rooms; vibrations and vibration control; Buildings, engines; architectural acoustics and acoustic comfort; TV studios and technical rooms. This presentation describes the Acoustic Project, phases I (1999), and II (2002), how it was possible to establish a common language with architects and engineers and the different specialties, to apply acoustic criteria and standards, the theoretical development and the projected acoustic solutions. (To be presented in Spanish.)

  13. The acoustic communities: Definition, description and ecological role.

    Farina, Almo; James, Philip

    2016-09-01

    An acoustic community is defined as an aggregation of species that produces sound by using internal or extra-body sound-producing tools. Such communities occur in aquatic (freshwater and marine) and terrestrial environments. An acoustic community is the biophonic component of a soundtope and is characterized by its acoustic signature, which results from the distribution of sonic information associated with signal amplitude and frequency. Distinct acoustic communities can be described according to habitat, the frequency range of the acoustic signals, and the time of day or the season. Near and far fields can be identified empirically, thus the acoustic community can be used as a proxy for biodiversity richness. The importance of ecoacoustic research is rapidly growing due to the increasing awareness of the intrusion of anthropogenic sounds (technophonies) into natural and human-modified ecosystems and the urgent need to adopt more efficient predictive tools to compensate for the effects of climate change. The concept of an acoustic community provides an operational scale for a non-intrusive biodiversity survey and analysis that can be carried out using new passive audio recording technology, coupled with methods of vast data processing and storage. PMID:27262416

  14. Increasing Access to Subsidized Artemisinin-based Combination Therapy through Accredited Drug Dispensing Outlets in Tanzania

    Gabra Michael

    2011-06-01

    Full Text Available Abstract Background In Tanzania, many people seek malaria treatment from retail drug sellers. The National Malaria Control Program identified the accredited drug dispensing outlet (ADDO program as a private sector mechanism to supplement the distribution of subsidized artemisinin-based combination therapies (ACTs from public facilities and increase access to the first-line antimalarial in rural and underserved areas. The ADDO program strengthens private sector pharmaceutical services by improving regulatory and supervisory support, dispenser training, and record keeping practices. Methods The government's pilot program made subsidized ACTs available through ADDOs in 10 districts in the Morogoro and Ruvuma regions, covering about 2.9 million people. The program established a supply of subsidized ACTs, created a price system with a cost recovery plan, developed a plan to distribute the subsidized products to the ADDOs, trained dispensers, and strengthened the adverse drug reactions reporting system. As part of the evaluation, 448 ADDO dispensers brought their records to central locations for analysis, representing nearly 70% of ADDOs operating in the two regions. ADDO drug register data were available from July 2007-June 2008 for Morogoro and from July 2007-September 2008 for Ruvuma. This intervention was implemented from 2007-2008. Results During the pilot, over 300,000 people received treatment for malaria at the 448 ADDOs. The percentage of ADDOs that dispensed at least one course of ACT rose from 26.2% during July-September 2007 to 72.6% during April-June 2008. The number of malaria patients treated with ACTs gradually increased after the start of the pilot, while the use of non-ACT antimalarials declined; ACTs went from 3% of all antimalarials sold in July 2007 to 26% in June 2008. District-specific data showed substantial variation among the districts in ACT uptake through ADDOs, ranging from ACTs representing 10% of all antimalarial sales

  15. High-temperature acoustic test facilities and methods

    Pearson, Jerome

    1994-09-01

    The Wright Laboratory is the Air Force center for air vehicles, responsible for developing advanced technology and incorporating it into new flight vehicles and for continuous technological improvement of operational air vehicles. Part of that responsibility is the problem of acoustic fatigue. With the advent of jet aircraft in the 1950's, acoustic fatigue of aircraft structure became a significant problem. In the 1960's the Wright Laboratory constructed the first large acoustic fatigue test facilities in the United States, and the laboratory has been a dominant factor in high-intensity acoustic testing since that time. This paper discusses some of the intense environments encountered by new and planned Air Force flight vehicles, and describes three new acoustic test facilities of the Wright Laboratory designed for testing structures in these dynamic environments. These new test facilities represent the state of the art in high-temperature, high-intensity acoustic testing and random fatigue testing. They will allow the laboratory scientists and engineers to test the new structures and materials required to withstand the severe environments of captive-carry missiles, augmented lift wings and flaps, exhaust structures of stealth aircraft, and hypersonic vehicle structures well into the twenty-first century.

  16. Acoustic engineering at Universidad de las Americas, Ecuador

    Bravo, Luis A.; Naranjo, Jaime O.; Tassara, Alberto

    2001-05-01

    Acoustics, like science, an instrument to develop new technologies, comfortable atmospheres, and pleasant sounds, has not had a sufficient push in Ecuador. The shortage of professionals in the area, and the social ignorance of the advances and benefits of acoustics have been part of the problem. The University of the Americas has taken the initiative to develop an undergraduate program-only in the country-of sound and acoustics engineering, to contribute to the formation of professional futures that fortify the recent labor market in the areas of audio, professional, and acoustic engineering. This work presents/displays the results of the studies made for the creation of the race, the curricular mesh, and its projections.

  17. Acoustic imaging of underground storage tank wastes

    Acoustics is a potential tool to determine the properties of high level wastes stored in Underground Storage Tanks. Some acoustic properties were successfully measured by a limited demonstration conducted in 114-TX. This accomplishment provides the basis for expanded efforts to qualify techniques which depend on the acoustic properties of tank wastes. This work is being sponsored by the Department of Energy under the Office of Science and Technology. In FY-1994, limited Tank Waste Remediation Systems EM-30 support was available at Hanford and Los Alamos National Laboratory. The Massachusetts Institute of Technology (MIT) and Earth Resources Laboratory (ERL) were engaged for analysis support, and Elohi Geophysics, Inc. for seismic testing services. Westinghouse-Hanford Company provided the testing and training, supplied the special engineering and safety analysis equipment and procedures, and provided the trained operators for the actual tank operations. On 11/9/94, limited in-tank tests were successfully conducted in tank 114-TX. This stabilized Single Shell Tank was reported as containing 16.8 feet of waste, the lower 6.28 feet of which contained interstitial liquid. Testing was conducted over the lower 12 feet, between two Liquid Observation Wells thirty feet apart. The ''quick-look'' data was reviewed on-site by MIT and Elohi

  18. Investigation of bulk acoustic microwaves excited by an interdigital transducer

    Reshotka O. G.

    2015-12-01

    Full Text Available Excitation of bulk and surface acoustic waves with the interdigital transducer (IDT, which is deposited on the surface of piezoelectric crystal, is widely used in the development of devices in acoustoelectronics and in the design of the microwave acousto-optic deflectors. Excitation of bulk acoustic waves by IDT in the devices on surface acoustic waves leads to the appearance of spurious signals. At the same time excitation of bulk acoustic waves with IDT from the surface of lithium niobate crystals allows creating high frequency acousto-optic deflectors, which makes possible to significantly simplify the technology of their production. Therefore, significant attention is paid to the task of excitation and distribution of bulk acoustic waves with IDT including recent times by the method of simulation of their excitation and distribution. The obtained theoretical results require experimental verification. This paper documents the visualization of acoustic beams excited with IDT from the XY-surface of lithium niobate crystals. The Bragg cells with LiNbO3 crystals coated with IDT with a different period of electrodes were manufactured for the experimental research of excitation and distribution of bulk acoustic waves. Visualization results have shown that the acoustic waves excited with IDT distribute in both the Fresnel zone and the Fraunhofer zone. The length of these zones is caused by individual elementary emitters of which consists the IDT (by their size. At the same time the far zone for IDT is located at distances much greater than the actual size of the LiNbO3 crystals. This peculiarity is not always taken into account when calculating diffraction. The achieved results can be used to design high-frequency acousto-optic devices, as well as in the development of devices based on surface acoustic waves.

  19. Flat acoustic lens by acoustic grating with curled slits

    Peng, Pai

    2014-10-01

    We design a flat sub-wavelength lens that can focus acoustic wave. We analytically study the transmission through an acoustic grating with curled slits, which can serve as a material with tunable impedance and refractive index for acoustic waves. The effective parameters rely on the geometry of the slits and are independent of frequency. A flat acoustic focusing lens by such acoustic grating with gradient effective refractive index is designed. The focusing effect is clearly observed in simulations and well predicted by the theory. We demonstrate that despite the large impedance mismatch between the acoustic lens and the matrix, the intensity at the focal point is still high due to Fabry-Perot resonance.

  20. Acoustic Tractor Beam

    Démoré, Christine E. M.; Dahl, Patrick M.; Yang, Zhengyi; Glynne-Jones, Peter; Melzer, Andreas; Cochran, Sandy; MacDonald, Michael P.; Spalding, Gabriel C.

    2014-05-01

    Negative radiation forces act opposite to the direction of propagation, or net momentum, of a beam but have previously been challenging to definitively demonstrate. We report an experimental acoustic tractor beam generated by an ultrasonic array operating on macroscopic targets (>1 cm) to demonstrate the negative radiation forces and to map out regimes over which they dominate, which we compare to simulations. The result and the geometrically simple configuration show that the effect is due to nonconservative forces, produced by redirection of a momentum flux from the angled sides of a target and not by conservative forces from a potential energy gradient. Use of a simple acoustic setup provides an easily understood illustration of the negative radiation pressure concept for tractor beams and demonstrates continuous attraction towards the source, against a net momentum flux in the system.

  1. Acoustic classification of dwellings

    Berardi, Umberto; Rasmussen, Birgit

    2014-01-01

    Schemes for the classification of dwellings according to different building performances have been proposed in the last years worldwide. The general idea behind these schemes relates to the positive impact a higher label, and thus a better performance, should have. In particular, focusing on sound...... insulation performance, national schemes for sound classification of dwellings have been developed in several European countries. These schemes define acoustic classes according to different levels of sound insulation. Due to the lack of coordination among countries, a significant diversity in terms of...... descriptors, number of classes, and class intervals occurred between national schemes. However, a proposal “acoustic classification scheme for dwellings” has been developed recently in the European COST Action TU0901 with 32 member countries. This proposal has been accepted as an ISO work item. This paper...

  2. 28th International Acoustical Imaging Symposium

    André, Michael P; Andre, Michael; Arnold, Walter; Bamber, Jeff; Burov, Valentin; Chubachi, Noriyoshi; Erikson, Kenneth; Ermert, Helmut; Fink, Mathias; Gan, Woon S; Granz, Bernd; Greenleaf, James; Hu, Jiankai; Jones, Joie P; Khuri-Yakub, Pierre; Laugier, Pascal; Lee, Hua; Lees, Sidney; Levin, Vadim M; Maev, Roman; Masotti, Leonardo; Nowicki, Andrzej; O’Brien, William; Prasad, Manika; Rafter, Patrick; Rouseff, Daniel; Thijssen, Johan; Tittmann, Bernard; Tortoli, Piero; Steen, Anton; Waag, Robert; Wells, Peter; Acoustical Imaging

    2007-01-01

    The International Acoustical Imaging Symposium has been held continuously since 1968 as a unique forum for advanced research, promoting the sharing of technology, developments, methods and theory among all areas of acoustics. The interdisciplinary nature of the Symposium and the wide international participation are two of its main strengths. Scientists from around the world present their papers in an informal environment conducive to lively discussion and cross-fertilization. The fact that a loyal community of scientists has supported this Series since 1968 is evidence of its impact on the field. The Symposium Series continues to thrive in a busy calendar of scientific meetings without the infrastructure of a professional society. It does so because those who attend and those who rely on the Proceedings as a well-known reference work acknowledge its value. This Volume 28 of the Proceedings likewise contains an excellent collection of papers presented in six major categories, offering both a broad perspective ...

  3. An injectable acoustic transmitter for juvenile salmon

    Deng, Z. D.; Carlson, T. J.; Li, H.; Xiao, J.; Myjak, M. J.; Lu, J.; Martinez, J. J.; Woodley, C. M.; Weiland, M. A.; Eppard, M. B.

    2015-01-01

    Salmon recovery and the potential detrimental effects of dams on fish have been attracting national attention due to the environmental and economic implications. In recent years acoustic telemetry has been the primary method for studying salmon passage. However, the size of the existing transmitters limits the minimum size of fish that can be studied, introducing a bias to the study results. We developed the first acoustic fish transmitter that can be implanted by injection instead of surgery. The new injectable transmitter lasts four times longer and weighs 30% less than other transmitters. Because the new transmitter costs significantly less to use and may substantially reduce adverse effects of implantation and tag burden, it will allow for study of migration behavior and survival of species and sizes of fish that have never been studied before. The new technology will lead to critical information needed for salmon recovery and the development of fish-friendly hydroelectric systems.

  4. Acoustic emission source modeling

    Hora P.

    2010-07-01

    Full Text Available The paper deals with the acoustic emission (AE source modeling by means of FEM system COMSOL Multiphysics. The following types of sources are used: the spatially concentrated force and the double forces (dipole. The pulse excitation is studied in both cases. As a material is used steel. The computed displacements are compared with the exact analytical solution of point sources under consideration.

  5. The acoustics of snoring.

    Pevernagie, Dirk; Aarts, Ronald M; De Meyer, Micheline

    2010-04-01

    Snoring is a prevalent disorder affecting 20-40% of the general population. The mechanism of snoring is vibration of anatomical structures in the pharyngeal airway. Flutter of the soft palate accounts for the harsh aspect of the snoring sound. Natural or drug-induced sleep is required for its appearance. Snoring is subject to many influences such as body position, sleep stage, route of breathing and the presence or absence of sleep-disordered breathing. Its presentation may be variable within or between nights. While snoring is generally perceived as a social nuisance, rating of its noisiness is subjective and, therefore, inconsistent. Objective assessment of snoring is important to evaluate the effect of treatment interventions. Moreover, snoring carries information relating to the site and degree of obstruction of the upper airway. If evidence for monolevel snoring at the site of the soft palate is provided, the patient may benefit from palatal surgery. These considerations have inspired researchers to scrutinize the acoustic characteristics of snoring events. Similarly to speech, snoring is produced in the vocal tract. Because of this analogy, existing techniques for speech analysis have been applied to evaluate snoring sounds. It appears that the pitch of the snoring sound is in the low-frequency range (noise-like', and has scattered energy content in the higher spectral sub-bands (>500 Hz). To evaluate acoustic properties of snoring, sleep nasendoscopy is often performed. Recent evidence suggests that the acoustic quality of snoring is markedly different in drug-induced sleep as compared with natural sleep. Most often, palatal surgery alters sound characteristics of snoring, but is no cure for this disorder. It is uncertain whether the perceived improvement after palatal surgery, as judged by the bed partner, is due to an altered sound spectrum. Whether some acoustic aspects of snoring, such as changes in pitch, have predictive value for the presence of

  6. Investigation of acoustic sensors to detect coconut rhinoceros beetle in Guam

    The coconut rhinoceros beetle, Oryctes rhinoceros, was accidentally introduced into Guam last year and now threatens the Island’s forests and tourist industry. These large insects can be detected easily with acoustic sensors, and procedures are being developed to incorporate acoustic technology int...

  7. Acoustic wave focusing in complex media using Nonlinear Time Reversal coded signal processing

    Dos Santos, S.; Dvořáková, Zuzana; Lints, M.; Kůs, V.; Salupere, A.; Převorovský, Zdeněk

    Brno : University of Technology, 2014. s. 144-145. ISBN 978-80-214-5019-6. [European Conference on Non-Destructive Testing (ECNDT 2014) /11./. 06.10.2014-10.10.2014, Praha] Institutional support: RVO:61388998 Keywords : ultrasonic testing (UT) * signal processing * TR-NEWS * Nonlinear Time Reversal * NDT * nonlinear acoustic s Subject RIV: BI - Acoustic s

  8. Teaching Acoustic Properties of Materials in Secondary School: Testing Sound Insulators

    Hernandez, M. I.; Couso, D.; Pinto, R.

    2011-01-01

    Teaching the acoustic properties of materials is a good way to teach physics concepts, extending them into the technological arena related to materials science. This article describes an innovative approach for teaching sound and acoustics in combination with sound insulating materials in secondary school (15-16-year-old students). Concerning the…

  9. Acoustic and electo-acoustic design of the Country Music Hall of Fame and Museum in Nashville

    Haas, Steve

    2003-04-01

    The Country Music Hall of Fame and Museum in Nashville is the newest major music museum to open in the United States. It represents the latest in acoustic and audio delivery technology to provide excellent sound quality and sound control for museum public, performance and exhibit spaces. The author will present some of the unique approaches and technologies that were first implemented into this facility and explain how the acoustic/electroacoustic interface allowed the Hall of Fame to maximize their use of sound in the exhibits as well as hold simultaneous special functions in many of the public spaces.

  10. Acoustic noise in magnetic resonance imaging: An ongoing issue

    Purpose: Acoustic noise creates a problem for both patients and staff within the magnetic resonance (MR) environment. This study qualitatively and quantitatively investigates the acoustic noise levels from two MR systems in one clinical department and demonstrates the adverse effects that the acoustic noise generated in magnetic resonance imaging (MRI) has on a patient's experience of an MRI examination. Methods: A questionnaire was distributed to consenting patients undergoing one of two specific MR examinations on two MR systems (System A and System B) of varying age and technology in one clinical department. These evaluated the patient's experience during the MRI examination. Physical measurements of the maximum acoustic noise levels produced by each system for various pulse sequences were also recorded using a sound level meter. Results: The results of the questionnaire survey demonstrated significantly greater tolerance of the acoustic noise levels of System B (mean noise level rating of 2.45 on LIKERT scale) in comparison to System A (mean noise level rating of 3.71 on LIKERT scale) (P = 0.001). Significantly lower noise level descriptions were also demonstrated (P = 0.01). The maximum recorded sound levels also confirmed that System B was quieter than the System A. Conclusion: It is has been demonstrated that the acoustic noise generated during an MRI examinations has an adverse effect on the patient experience during the examination. However, new technology has significantly reduced these effects and is improving patient comfort in MRI. It was shown quantitatively that the newer system's advanced gradient technology was quieter than the older system, in terms of the acoustic noise levels associated with a range of common pulse sequences.

  11. High-Frequency Seafloor Acoustics

    Jackson, Darrell R

    2007-01-01

    High-Frequency Seafloor Acoustics is the first book in a new series sponsored by the Office of Naval Research on the latest research in underwater acoustics. This exciting new title provides ready access to experimental data, theory, and models relevant to high-frequency seafloor acoustics and will be of interest to sonar engineers and researchers working in underwater acoustics. The physical characteristics of the seafloor affecting acoustic propagation and scattering are covered, including physical and geoacoustic properties and surface roughness. Current theories for acoustic propagation in sediments are presented along with corresponding models for reflection, scattering, and seafloor penetration. The main text is backed up by an extensive bibliography and technical appendices.

  12. Fundamentals of Shallow Water Acoustics

    Katsnelson, Boris; Lynch, James

    2012-01-01

    Shallow water acoustics (SWA), the study of how low and medium frequency sound propagates and scatters on the continental shelves of the world's oceans, has both technical interest and a large number of practical applications. Technically, shallow water poses an interesting medium for the study of acoustic scattering, inverse theory, and propagation physics in a complicated oceanic waveguide. Practically, shallow water acoustics has interest for geophysical exploration, marine mammal studies, and naval applications. Additionally, one notes the very interdisciplinary nature of shallow water acoustics, including acoustical physics, physical oceanography, marine geology, and marine biology. In this specialized volume, the authors, all of whom have extensive at-sea experience in U.S. and Russian research efforts, have tried to summarize the main experimental, theoretical, and computational results in shallow water acoustics, with an emphasis on providing physical insight into the topics presented.

  13. Latest Trends in Acoustic Sensing

    Cinzia Caliendo

    2014-03-01

    Full Text Available Acoustics-based methods offer a powerful tool for sensing applications. Acoustic sensors can be applied in many fields ranging from materials characterization, structural health monitoring, acoustic imaging, defect characterization, etc., to name just a few. A proper selection of the acoustic wave frequency over a wide spectrum that extends from infrasound (<20 Hz up to ultrasound (in the GHz–band, together with a number of different propagating modes, including bulk longitudinal and shear waves, surface waves, plate modes, etc., allow acoustic tools to be successfully applied to the characterization of gaseous, solid and liquid environments. The purpose of this special issue is to provide an overview of the research trends in acoustic wave sensing through some cases that are representative of specific applications in different sensing fields.

  14. Wireless Acoustic Measurement System

    Anderson, Paul D.; Dorland, Wade D.; Jolly, Ronald L.

    2007-01-01

    A prototype wireless acoustic measurement system (WAMS) is one of two main subsystems of the Acoustic Prediction/ Measurement Tool, which comprises software, acoustic instrumentation, and electronic hardware combined to afford integrated capabilities for predicting and measuring noise emitted by rocket and jet engines. The other main subsystem is described in the article on page 8. The WAMS includes analog acoustic measurement instrumentation and analog and digital electronic circuitry combined with computer wireless local-area networking to enable (1) measurement of sound-pressure levels at multiple locations in the sound field of an engine under test and (2) recording and processing of the measurement data. At each field location, the measurements are taken by a portable unit, denoted a field station. There are ten field stations, each of which can take two channels of measurements. Each field station is equipped with two instrumentation microphones, a micro- ATX computer, a wireless network adapter, an environmental enclosure, a directional radio antenna, and a battery power supply. The environmental enclosure shields the computer from weather and from extreme acoustically induced vibrations. The power supply is based on a marine-service lead-acid storage battery that has enough capacity to support operation for as long as 10 hours. A desktop computer serves as a control server for the WAMS. The server is connected to a wireless router for communication with the field stations via a wireless local-area network that complies with wireless-network standard 802.11b of the Institute of Electrical and Electronics Engineers. The router and the wireless network adapters are controlled by use of Linux-compatible driver software. The server runs custom Linux software for synchronizing the recording of measurement data in the field stations. The software includes a module that provides an intuitive graphical user interface through which an operator at the control server

  15. Magneto-photo-acoustic imaging

    Qu, Min; Mallidi, Srivalleesha; Mehrmohammadi, Mohammad; Truby, Ryan; Homan, Kimberly; Joshi, Pratixa; Chen, Yun-Sheng; Sokolov, Konstantin; Emelianov, Stanislav

    2011-01-01

    Magneto-photo-acoustic imaging, a technique based on the synergy of magneto-motive ultrasound, photoacoustic and ultrasound imaging, is introduced. Hybrid nanoconstructs, liposomes encapsulating gold nanorods and iron oxide nanoparticles, were used as a dual-contrast agent for magneto-photo-acoustic imaging. Tissue-mimicking phantom and macrophage cells embedded in ex vivo porcine tissue were used to demonstrate that magneto-photo-acoustic imaging is capable of visualizing the location of cel...

  16. Room acoustic auralization with Ambisonics

    Polack, Jean-Dominique; Leão Figueiredo, Fábio

    2012-01-01

    International audience During the year of 2009, the room acoustics group of the LAM (Équipe Lutheries, Acoustique, Musique de l’Institut Jean Le Rond d’Alembert - Université Pierre et Marie Curie, Paris) performed a series of acoustical measurements in music halls in Paris. The halls were chosen in regarding their importance to the historic, architectural or acoustic domains. The measured ensemble of fourteen rooms includes quite different architectural designs. The measurements were carri...

  17. Steam sterilization and automatic dispensing of [18F]fludeoxyglucose (FDG) for injection

    For the purpose of implementing steam sterilization of 2-[18F]FDG (FDG) in the final container into routine production, we have validated and established a fully automated dispensing and sterilization system, thereby considerably reducing the radiation burden to the personnel. Methods: The commercially available system combines aseptic dispensing of the product solution under a miniaturized laminar flow unit with subsequent steam sterilization, realized by heating of the product in the final containers by an autoclave included in the dispensing unit, thus incorporating current pharmaceutical manufacturing standards for the production of parental radiopharmaceuticals. The efficiency of the used sterilization cycle, the stability of FDG under the conditions of sterilization and the stability of the final product towards radiolysis was investigated with respect to various pH-formulations. Results: The system was found to be fully valid for filling of vials in a laminar flow class A (US-class 100) environment and for sterilization of FDG in the final container. The pH for sterilizing FDG solutions must be slightly acidic to avoid decomposition. A pH of 5.5 appears to be optimal and gives FDG of very high radiochemical purity (∼99%). In addition, radiolysis of FDG in solutions of high activity concentration was significantly lower at pH 5.5 than at neutral pH. Conclusion: Terminal sterilization enables the production of FDG in full compliance with GMP-regulations even in Class C or D (US class 10,000 or 100,000) laboratories

  18. Steam sterilization and automatic dispensing of [{sup 18}F]fludeoxyglucose (FDG) for injection

    Karwath, Pascal [Department of Nuclear Medicine, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany) and MC-Pharma GmbH (MCP), Bonn (Germany)]. E-mail: p.karwath@uni-bonn.de; Sartor, Johannes [MC-Pharma GmbH (MCP), Bonn (Germany); Gries, Wolfgang [MC-Pharma GmbH (MCP), Bonn (Germany); Wodarski, Christine [MC-Pharma GmbH (MCP), Bonn (Germany); Dittmar, Claus [MC-Pharma GmbH (MCP), Bonn (Germany); Biersack, Hans J. [Department of Nuclear Medicine, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany); Guhlke, Stefan [Department of Nuclear Medicine, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany) and MC-Pharma GmbH (MCP), Bonn (Germany)]. E-mail: stefan.guhlke@ukb.uni-bonn.de

    2005-04-01

    For the purpose of implementing steam sterilization of 2-[{sup 18}F]FDG (FDG) in the final container into routine production, we have validated and established a fully automated dispensing and sterilization system, thereby considerably reducing the radiation burden to the personnel. Methods: The commercially available system combines aseptic dispensing of the product solution under a miniaturized laminar flow unit with subsequent steam sterilization, realized by heating of the product in the final containers by an autoclave included in the dispensing unit, thus incorporating current pharmaceutical manufacturing standards for the production of parental radiopharmaceuticals. The efficiency of the used sterilization cycle, the stability of FDG under the conditions of sterilization and the stability of the final product towards radiolysis was investigated with respect to various pH-formulations. Results: The system was found to be fully valid for filling of vials in a laminar flow class A (US-class 100) environment and for sterilization of FDG in the final container. The pH for sterilizing FDG solutions must be slightly acidic to avoid decomposition. A pH of 5.5 appears to be optimal and gives FDG of very high radiochemical purity ({approx}99%). In addition, radiolysis of FDG in solutions of high activity concentration was significantly lower at pH 5.5 than at neutral pH. Conclusion: Terminal sterilization enables the production of FDG in full compliance with GMP-regulations even in Class C or D (US class 10,000 or 100,000) laboratories.

  19. Using Multispectral Imaging to Measure Temperature Profiles and Emissivity of Large Thermionic Dispenser, Cathodes

    Thermionic dispenser cathodes are widely used in modern high-power microwave tubes. Use of these cathodes has led to significant improvement in performance. In recent years these cathodes have been used in electron linear accelerators (LINACs), particularly in induction LINACs, such as the Experimental Test Accelerator at Lawrence Livermore National Laboratory and the Relativistic Test Accelerator at Lawrence Berkeley National Laboratory. For induction LINACs, the thermionic dispenser cathode provides greater reproducibility, longer pulse lengths, and lower emittance beams than does a field emission cathode. Los Alamos National Laboratory is fabricating a dual-axis X-ray radiography machine called dual-axis radiograph hydrodynamic test (DARHT). The second axis of DARHT consists of a 2-kA, 20-MeV induction LINAC that uses a 3.2-MeV electron gun with a tungsten thermionic-dispenser cathode. Typically the DARHT cathode current density is 10 A/cm2 at 1050 C. Under these conditions current density is space-charge limited, which is desirable since current density is independent of temperature. At lower temperature (the temperature-limited regime) there are variations in the local current density due to a nonuniform temperature profile. To obtain the desired uniform current density associated with space-charge limited operation, the coolest area on the cathode must be at a sufficiently high temperature so that the emission is space-charge limited. Consequently, the rest of the cathode is emitting at the same space-charge-limited current density but is at a higher temperature than necessary. Because cathode lifetime is such a strong function of cathode temperature, there is a severe penalty for nonuniformity in the cathode temperature. For example, a temperature increase of 50 C means cathode lifetime will decrease by a factor of at least four. Therefore, we are motivated to measure the temperature profiles of our large-area cathodes

  20. Distributed acoustic sensing for pipeline monitoring

    Hill, David; McEwen-King, Magnus [OptaSense, QinetiQ Ltd., London (United Kingdom)

    2009-07-01

    Optical fibre is deployed widely across the oil and gas industry. As well as being deployed regularly to provide high bandwidth telecommunications and infrastructure for SCADA it is increasingly being used to sense pressure, temperature and strain along buried pipelines, on subsea pipelines and downhole. In this paper we present results from the latest sensing capability using standard optical fibre to detect acoustic signals along the entire length of a pipeline. In Distributed Acoustic Sensing (DAS) an optical fibre is used for both sensing and telemetry. In this paper we present results from the OptaSense{sup TM} system which has been used to detect third party intervention (TPI) along buried pipelines. In a typical deployment the system is connected to an existing standard single-mode fibre, up to 50km in length, and was used to independently listen to the acoustic / seismic activity at every 10 meter interval. We will show that through the use of advanced array processing of the independent, simultaneously sampled channels it is possible to detect and locate activity within the vicinity of the pipeline and through sophisticated acoustic signal processing to obtain the acoustic signature to classify the type of activity. By combining spare fibre capacity in existing buried fibre optic cables; processing and display techniques commonly found in sonar; and state-of-the-art in fibre-optic distributed acoustic sensing, we will describe the new monitoring capabilities that are available to the pipeline operator. Without the expense of retrofitting sensors to the pipeline, this technology can provide a high performance, rapidly deployable and cost effective method of providing gapless and persistent monitoring of a pipeline. We will show how this approach can be used to detect, classify and locate activity such as; third party interference (including activity indicative of illegal hot tapping); real time tracking of pigs; and leak detection. We will also show how an

  1. Evaluation of antibiotics dispensing profile in Tubarão, Santa Catarina, Brazil

    Claudia Rauber

    2009-12-01

    Full Text Available Antibiotics are drugs widely used in prophylaxis and treatment of a great number of diseases. However, their use must be carefully controlled as acquisition in pharmacies, often without medical prescription, is elevated. The role of pharmacists in these circumstances is to practice dispensation in a rational manner. Through a structured questionnaire with open and closed questions, this study investigated the profile of antibiotics dispensed in pharmacies of Tubarão, Santa Catarina, Brazil. From the responses, it was observed that 85.0% dispense this class of medicine without medical prescription, mainly for treatment of respiratory (62.8% and urinary (12.0% tract disorders. Moreover, pharmacists' guidance was largely focused on posology (66.6% and drug interaction (12.6%, in addition to the interactions with contraceptives, alcohol and milk. The importance of avoiding antibiotics dispensation without medical prescription must be emphasized, as well as the benefits of educating the population to promote the rational use of medicines.Antibióticos são fármacos amplamente utilizados na profilaxia e no tratamento de grande número de doenças. Entretanto, seu uso deve ser cuidadosamente controlado nas farmácias, uma vez que nestas a aquisição sem prescrição médica é elevada. O papel dos farmacêuticos nessas circunstâncias é o de praticar a dispensação de maneira racional. Por meio de questionário estruturado, com questões abertas e fechadas, investigou-se o perfil dos antibióticos dispensados em farmácias de Tubarão, Santa Catarina, Brasil. Pelas respostas, observou-se que 85% das dispensa essa classe de medicamentos sem prescrição médica, principalmente para o tratamento de problemas dos tratos respiratório (62,8% e urinário (12,0%. Além disso, a orientação dos farmacêuticos se focou amplamente na posologia (66,6%e nas interações com fármacos (12,6%, em adição às interações com anticoncepcionais, álcool e

  2. A model for drug dispensing service based on the care process in the Brazilian health system

    Luciano Soares

    2013-03-01

    Full Text Available Access to medication emphasizes the availability of the product at the expense of providing a service. The goal of this paper is to propose a theoretical model for a drug dispensing service, beginning with a reflection on the current realities of the Unified Health System and drug dispensation in Brazil. A conceptual analytical research made by a methodological course called disciplined imagination was mainly the approach applied to develop the model. The drug dispensing service is part of the care process, which considers access as an attribute; reception, connection and accountability, management, and clinical pharmaceutical aspects as components; and the rational use of drugs as the purpose. The proposed model addresses access to the dispensing service and demands a reorientation of routines, instruments, and practices.O acesso a medicamentos enfatiza a disponibilidade do produto em detrimento da provisão de um serviço. O objetivo deste trabalho é propor um modelo teórico para um serviço de dispensação de medicamentos, iniciando com uma reflexão sobre a realidade atual do Sistema Único de Saúde e a dispensação de medicamentos no Brasil. Uma pesquisa analítica conceitual realizada por meio de um percurso metodológico chamado de imaginação disciplinada constituiu a estratégia principal para o desenvolvimento do modelo. O serviço de dispensação é parte do processo de cuidado, o qual considera o acesso como um atributo; os aspectos acolhimento, vínculo e responsabilização, gestão e clínica farmacêutica como componentes e o uso racional de medicamentos como o propósito. O modelo proposto direciona o acesso para o serviço de dispensação e demanda a reorientação de rotinas, instrumentos e práticas.

  3. The study of neutron burst shape of a neutron tube driven by dispenser cathode

    Grishnyaev, Evgeny; Polosatkin, Sergey

    2016-08-01

    A slim-shaped portable DD-neutron generator is developed at Budker institute of Nuclear Physics. The generator is a combination of Cockcroft-Walton voltage multiplier and a sealed gas-filled neutron tube driven by dispenser cathode. Neutron burst shape in pulsed mode of neutron tube operation is measured with stroboscopic time spectrometry, implemented on scintillation detector, and modeled with Comsol Script 1.3 and Comsol Multiphysics 3.5. Modeling appears to be in good agreement with experimental results. Measured pulse rise and fall times are 110 ns and 100 ns respectively.

  4. Increase in Naloxone Prescriptions Dispensed in US Retail Pharmacies Since 2013.

    Jones, Christopher M; Lurie, Peter G; Compton, Wilson M

    2016-04-01

    Distribution of naloxone, traditionally through community-based naloxone programs, is a component of a comprehensive strategy to address the epidemic of prescription opioid and heroin overdose deaths in the United States. Recently, there has been increased focus on naloxone prescription in the outpatient setting, particularly through retail pharmacies, yet data on this practice are sparse. We found an 1170% increase in naloxone dispensing from US retail pharmacies between the fourth quarter of 2013 and the second quarter of 2015. These findings suggest that prescribing naloxone in the outpatient setting complements traditional community-based naloxone programs. PMID:26890174

  5. International Space Station (ISS) Potable Water Dispenser (PWD) Beverage Adapter (BA) Redesign

    Edgerly, Rachel; Benoit, Jace; Shindo, David

    2012-01-01

    The Potable Water Dispenser used on the International Space Station (ISS) interfaces with food and drink packages using the Beverage Adapter and Needle. Unexpected leakage has been seen in this interface. The Beverage Adapter used on ]orbit was returned to the ground for Test, Teardown, and Evaluation. The results of that investigation prompted a redesign of the Beverage Adapter and Needle. The Beverage Adapter materials were changed to be more corrosion resistant, and the Needle was redesigned to preclude leakage. The redesigns have been tested and proven.

  6. Combined Environment Acoustic Chamber (CEAC)

    Federal Laboratory Consortium — Purpose: The CEAC imposes combined acoustic, thermal and mechanical loads on aerospace structures. The CEAC is employed to measure structural response and determine...

  7. Truck acoustic data analyzer system

    Haynes, Howard D.; Akerman, Alfred; Ayers, Curtis W.

    2006-07-04

    A passive vehicle acoustic data analyzer system having at least one microphone disposed in the acoustic field of a moving vehicle and a computer in electronic communication the microphone(s). The computer detects and measures the frequency shift in the acoustic signature emitted by the vehicle as it approaches and passes the microphone(s). The acoustic signature of a truck driving by a microphone can provide enough information to estimate the truck speed in miles-per-hour (mph), engine speed in rotations-per-minute (RPM), turbocharger speed in RPM, and vehicle weight.

  8. Development of an automated dispenser for the delivery of medicinal or vaccine-laden baits to raccoons (Procyon lotor).

    Smyser, Timothy J; Redding, James V; Bevis, Crystal M; Page, L Kristen; Swihart, Robert K

    2015-04-01

    Medicinal baits are distributed to manage zoonotic diseases, including raccoon (Procyon lotor) rabies, but efficient distribution strategies are needed for suburban environments. We developed an automated dispenser that transfers fishmeal polymer baits at user-specified intervals from a magazine to a receptacle fitted with a filter that exploits raccoon dexterity to limit consumption by nontarget species. We introduce the concept of automated dispensers and describe bait removal success rates for raccoons versus nontarget species. We monitored visitation with remote cameras after deploying a dispenser, programmed to present two baits per night, in three disjunct forest patches in northwest Indiana. Raccoons removed 72% of baits; nontarget, white-footed mice (Peromyscus leucopus) removed 11%; Virginia opossums (Didelphis virginiana) removed 9%. Bait removal success varied significantly between raccoons (76%) and opossums (21%), improving bait delivery specificity relative to hand baiting. Accumulation of baits in receptacles resulted in excess (more than one) bait consumption (39% of baits consumed by raccoons were excess), suggesting design improvements are needed to present additional baits only after previous baits have been consumed. Automated dispensers successfully sustained bait availability throughout the operational period. Subsequent research is needed to determine whether a sustained availability of baits achieved with automated dispensers is more effective for the treatment of raccoons in suburban environments than traditional distribution methods. PMID:25647587

  9. A Review of the Anthropometric Characteristics, Grading and Dispensation of Junior and Youth Rugby Union Players in Australia.

    Patton, Declan Alexander; McIntosh, Andrew Stuart; Denny, Greg

    2016-08-01

    The grading of Australian junior and youth rugby union players has received substantial media attention in recent years. Media reports have focussed on size mismatches observed between players, especially players with Polynesian heritage, and the concerned parents who fear for the safety of their child owing to perceived mismatches. Although such concerns are well meaning, few media reports recognise the need for substantial evidence to determine the best grading system for junior and youth rugby union players. The current study reviewed relevant literature pertinent to the grading and dispensation of junior and youth rugby union players. Using primary and secondary search strategies, a total of 33 articles reporting the anthropometric characteristics of junior and youth rugby players were identified. Anthropometric data from the literature were compared with normative population data and currently used dispensation criteria. Junior and youth rugby players were found to be taller and heavier than normative population data. Current dispensation criteria, in terms of body mass, were found to vary and it is suggested that criteria be revised and standardised across rugby unions throughout Australia. Although it is acknowledged that other factors are important for grading players, anthropometric characteristics should be considered as potential dispensation criteria to supplement current age-based grading for junior and youth rugby union players. Measuring the body mass and stature of each junior player upon pre-season registration is suggested, which would provide data to establish valid dispensation criteria for the following season. PMID:26886476

  10. Opticians, Dispensing

    ... More Sources of Data Publications Latest Publications » The Economics Daily Monthly Labor Review Beyond the Numbers Spotlight on Statistics Reports & Bulletins Commissioner's Corner Career Outlook Occupational Outlook Handbook Handbook of Methods Research Papers Copyright Information Contact & ...

  11. Modifying the acoustic impedance of polyurea-based composites

    Nantasetphong, Wiroj; Amirkhizi, Alireza V.; Jia, Zhanzhan; Nemat-Nasser, Sia

    2013-04-01

    Acoustic impedance is a material property that depends on mass density and acoustic wave speed. An impedance mismatch between two media leads to the partial reflection of an acoustic wave sent from one medium to another. Active sonar is one example of a useful application of this phenomenon, where reflected and scattered acoustic waves enable the detection of objects. If the impedance of an object is matched to that of the surrounding medium, however, the object may be hidden from observation (at least directly) by sonar. In this study, polyurea composites are developed to facilitate such impedance matching. Polyurea is used due to its excellent blast-mitigating properties, easy casting, corrosion protection, abrasion resistance, and various uses in current military technology. Since pure polyurea has impedance higher than that of water (the current medium of interest), low mass density phenolic microballoon particles are added to create composite materials with reduced effective impedances. The volume fraction of particles is varied to study the effect of filler quantity on the acoustic impedance of the resulting composite. The composites are experimentally characterized via ultrasonic measurements. Computational models based on the method of dilute-randomly-distributed inclusions are developed and compared with the experimental results. These experiments and models will facilitate the design of new elastomeric composites with desirable acoustic impedances.

  12. Acoustic transparency and slow sound using detuned acoustic resonators

    Santillan, Arturo Orozco; Bozhevolnyi, Sergey I.

    2011-01-01

    We demonstrate that the phenomenon of acoustic transparency and slowsound propagation can be realized with detuned acoustic resonators (DAR), mimicking thereby the effect of electromagnetically induced transparency (EIT) in atomic physics. Sound propagation in a pipe with a series of side...

  13. Ares I Scale Model Acoustic Test Lift-Off Acoustics

    Counter, Douglas D.; Houston, Janie D.

    2011-01-01

    The lift-off acoustic (LOA) environment is an important design factor for any launch vehicle. For the Ares I vehicle, the LOA environments were derived by scaling flight data from other launch vehicles. The Ares I LOA predicted environments are compared to the Ares I Scale Model Acoustic Test (ASMAT) preliminary results.

  14. Taming Acoustic Cavitation

    Rivas, David Fernandez; Enriquez, Oscar R; Versluis, Michel; Prosperetti, Andrea; Gardeniers, Han; Lohse, Detlef

    2012-01-01

    In this fluid dynamics video we show acoustic cavitation occurring from pits etched on a silicon surface. By immersing the surface in a liquid, gas pockets are entrapped in the pits which upon ultrasonic insonation, are observed to shed cavitation bubbles. Modulating the driving pressure it is possible to induce different behaviours based on the force balance that determines the interaction among bubbles and the silicon surface. This system can be used for several applications like sonochemical water treatment, cleaning of surfaces with deposited materials such as biofilms.

  15. Dynamic acoustic tractor beams

    Mitri, F. G.

    2015-03-01

    Pulling a sphere and vibrating it around an equilibrium position by amplitude-modulation in the near-field of a single finite circular piston transducer is theoretically demonstrated. Conditions are found where a fluid hexane sphere (with arbitrary radius) chosen as an example, centered on the axis of progressive propagating waves and submerged in non-viscous water, experiences an attractive (steady) force pulling it towards the transducer, as well as an oscillatory force forcing it to vibrate back-and-forth. Numerical predictions for the dynamic force illustrate the theory and suggest an innovative method in designing dynamic acoustical tractor beams.

  16. Dynamic acoustic tractor beams

    Mitri, F. G., E-mail: F.G.Mitri@ieee.org [Chevron, Area 52 Technology – ETC, Santa Fe, New Mexico 87508 (United States)

    2015-03-07

    Pulling a sphere and vibrating it around an equilibrium position by amplitude-modulation in the near-field of a single finite circular piston transducer is theoretically demonstrated. Conditions are found where a fluid hexane sphere (with arbitrary radius) chosen as an example, centered on the axis of progressive propagating waves and submerged in non-viscous water, experiences an attractive (steady) force pulling it towards the transducer, as well as an oscillatory force forcing it to vibrate back-and-forth. Numerical predictions for the dynamic force illustrate the theory and suggest an innovative method in designing dynamic acoustical tractor beams.

  17. Lecture Notes On Acoustics

    This book mentions string vibration and wave, one-dimension wave and wave equation, characteristic impedance, governing equation of string, and wave energy from string, wave equation of wave and basic physical quantity like one-dimension wave equation, sound unit, sound intensity and energy, sound movement in a surface of discontinuity with transmission loss of sound by partition, and Snell's law, radiation, scatter and diffraction and sound in closed space with Sabine's theory, sound characteristic of closed space and duct acoustics.

  18. Acoustic analog of a free-electron laser

    As well known, at the present time there are many types of laser the operation of which is based on the stimulated emission of light by an active medium. Lasers are generators of coherent electromagnetic waves in the range from ultraviolet to submillimeters. But acoustic analogs of such devices have not been created up to now in spite of the progress in laser technology. Meanwhile, an acoustic laser could have a lot of interesting applications. Recently a theoretical scheme for an acoustic laser was proposed by the present author. A liquid dielectric with dispersed particles was considered as an active medium. The pumping was created by an oscillating electric field deforming dispersed particle volumes. Different types of oils or distilled water can serve as a liquid dielectric with gas bubbles as dispersed particles. Gas bubbles in water can be created by an electrolysis. The phase bunching of the initially incoherent emitters (gas bubbles) was realized by acoustic radiation forces. This scheme is an analog of the free-electron laser (FEL). It was shown that two types of losses must be overcome for the beginning of a generation. The first type results from the energy dissipation in the active medium and the second one is caused by radiation losses at the boundaries of the resonator. The purposes of this report are: (1) to discuss the analogies between the acoustic laser and FEL; (2) to propose an effective scheme of an acoustic laser with a mechanical pumping (by a piezoelectric emitter of the piston type); (3) to consider the schemes of acoustic lasers with the different types of the resonators (rectangular and cylindrical); (4) to discuss the possibility of the creation of an impact acoustic laser (5) to discuss the experimental works which are planned to be carried out in cooperation with prof. L.A. Crum

  19. Prototype of a Questionnaire and Quiz System for Supporting Increase of Health Awareness During Wait Time in Dispensing Pharmacy

    Toda, Takeshi; Chen, Poa-Min; Ozaki, Shinya; Ideguchi, Naoko; Miyaki, Tomoko; Nanbu, Keiko; Ikeda, Keiko

    For quit-smoking clinic and its campaign, there was a need for pharmacists to investigate pediatric patient's parent consciousness to tobacco harm utilizing wait time in a pediatric dispensing pharmacy. In this research, we developed the questionnaire and quiz total system using the tablet for user interface, in which people can easily answer the questionnaire/quiz and quickly see the total results on the spot in order to enhance their consciousness to the tobacco harm. The system also provides their tobacco dependence level based on the questionnaire results and some advice for their health and dietary habits due to the tobacco dependence level. From a field trial with one hundred four examinees in the pediatric dispensing pharmacy, the user interface was useful compared to conventional questionnaire form. The system could enhance their consciousness to tobacco harm and make their beneficial use of waiting time in dispensing pharmacy. Some interesting suggestions for improvement and new services were also obtained.

  20. Acoustic Emission Analysis Applet (AEAA) Software

    Nichols, Charles T.; Roth, Don J.

    2013-01-01

    NASA Glenn Research and NASA White Sands Test Facility have developed software supporting an automated pressure vessel structural health monitoring (SHM) system based on acoustic emissions (AE). The software, referred to as the Acoustic Emission Analysis Applet (AEAA), provides analysts with a tool that can interrogate data collected on Digital Wave Corp. and Physical Acoustics Corp. software using a wide spectrum of powerful filters and charts. This software can be made to work with any data once the data format is known. The applet will compute basic AE statistics, and statistics as a function of time and pressure (see figure). AEAA provides value added beyond the analysis provided by the respective vendors' analysis software. The software can handle data sets of unlimited size. A wide variety of government and commercial applications could benefit from this technology, notably requalification and usage tests for compressed gas and hydrogen-fueled vehicles. Future enhancements will add features similar to a "check engine" light on a vehicle. Once installed, the system will ultimately be used to alert International Space Station crewmembers to critical structural instabilities, but will have little impact to missions otherwise. Diagnostic information could then be transmitted to experienced technicians on the ground in a timely manner to determine whether pressure vessels have been impacted, are structurally unsound, or can be safely used to complete the mission.

  1. Improving material-specific dispense processes for low-defect coatings

    Brakensiek, Nick; Braggin, Jennifer; Berron, John; Ramirez, Raul; Anderson, Karl; Smith, Brian

    2011-04-01

    The drive to smaller, less expensive, and faster devices requires radical changes in material development. The increased material requirements drive complex processes that in turn drive equipment requirements. For the photolithography area this demand for improved materials is seen in growing requests for device level-specific tuning of organic bottom antireflective coatings (BARCs) or photoresists for certain imaging requirements, such as numerical aperture, immersion conditions, and optical parameters. To test and utilize the myriad of BARC materials, there is a need to install them on a coater-track quickly and efficiently. Installation typically requires a new filter installation, dispense line cleaning, and usually a minimum of 8-10 L of material to clear out bubbles and other nuisance defects before coating test wafers. As the number of materials increases, the ability to quickly prime a new filter becomes increasingly important. In this study, the Entegris IntelliGen® Mini dispense system was utilized to test various pump priming processes to ultimately minimize the volume purged to reach a defect baseline. In addition, the impacts of the filter media and filter retention on priming efficiency were studied. Results show that priming processes that were not matched to the filter in use could actually cause the defects to increase during the process, thus requiring additional purging to reach baseline, and thereby negating any time or volume savings. Properly programmed priming recipes reduced the purging time and the purging volume by 50-70%.

  2. Economic evaluation of task-shifting approaches to the dispensing of anti-retroviral therapy

    Foster Nicola

    2012-09-01

    Full Text Available Abstract Background A scarcity of human resources for health has been identified as one of the primary constraints to the scale-up of the provision of Anti-Retroviral Treatment (ART. In South Africa there is a particularly severe lack of pharmacists. The study aims to compare two task-shifting approaches to the dispensing of ART: Indirectly Supervised Pharmacist’s Assistants (ISPA and Nurse-based pharmaceutical care models against the standard of care which involves a pharmacist dispensing ART. Methods A cross-sectional mixed methods study design was used. Patient exit interviews, time and motion studies, expert interviews and staff costs were used to conduct a costing from the societal perspective. Six facilities were sampled in the Western Cape province of South Africa, and 230 patient interviews conducted. Results The ISPA model was found to be the least costly task-shifting pharmaceutical model. However, patients preferred receiving medication from the nurse. This related to a fear of stigma and being identified by virtue of receiving ART at the pharmacy. Conclusions While these models are not mutually exclusive, and a variety of pharmaceutical care models will be necessary for scale up, it is useful to consider the impact of implementing these models on the provider, patient access to treatment and difficulties in implementation.

  3. RET/GFRα Signals Are Dispensable for Thymic T Cell Development In Vivo

    Almeida, Afonso Rocha Martins; Arroz-Madeira, Sílvia; Fonseca-Pereira, Diogo; Ribeiro, Hélder; Lasrado, Reena; Pachnis, Vassilis; Veiga-Fernandes, Henrique

    2012-01-01

    Identification of thymocyte regulators is a central issue in T cell biology. Interestingly, growing evidence indicates that common key molecules control neuronal and immune cell functions. The neurotrophic factor receptor RET mediates critical functions in foetal hematopoietic subsets, thus raising the possibility that RET-related molecules may also control T cell development. We show that Ret, Gfra1 and Gfra2 are abundantly expressed by foetal and adult immature DN thymocytes. Despite the developmentally regulated expression of these genes, analysis of foetal thymi from Gfra1, Gfra2 or Ret deficient embryos revealed that these molecules are dispensable for foetal T cell development. Furthermore, analysis of RET gain of function and Ret conditional knockout mice showed that RET is also unnecessary for adult thymopoiesis. Finally, competitive thymic reconstitution assays indicated that Ret deficient thymocytes maintained their differentiation fitness even in stringent developmental conditions. Thus, our data demonstrate that RET/GFRα signals are dispensable for thymic T cell development in vivo, indicating that pharmacological targeting of RET signalling in tumours is not likely to result in T cell production failure. PMID:23300832

  4. Japanese Community Pharmacists' Dispensing Influences Medicine Price Reduction more than Prescription Numbers.

    Yokoi, Masayuki; Tashiro, Takao

    2016-01-01

    This study examined the economic efficiency of the separation of prescription and dispensation medicines between doctors in medical institutions and pharmacists in pharmacies. The separation system in Japanese prefectures was examined with publicly available data (Ministry of Health, Labour and Welfare, 2012-2014; retrieved from http://www.mhlw.go.jp/topics/medias/year). We investigated whether the separation system reduces the number of medicines or the medication cost of a prescription because of separating the economic management between prescribing and dispensing and the effect of mutual observation between doctors and pharmacists. It is optional for Japanese medical institutions to participate in the separation system. Consequently, the spreading rate of the separation system in each administrative district is highly variable. We examined the separation system effect using the National Healthcare Insurance data for three years, 2012-2014. We tested whether the separation system ratio for each prefecture was significantly correlated to the medication price or the number of medicines on a prescription. If spreading the separation system influenced the price of prescribed daily medications or the number of medicines, the correlation would be significant. As a result, the medication price was significantly negatively correlated with the separation system ratio, but the number of medicines was not significant. Therefore, the separation system was effective in reducing daily medication cost but had little influence on reducing the number of daily medicines. This was observed over three years in Japan. PMID:27157157

  5. Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development.

    Rijpma, Sanna R; van der Velden, Maarten; Annoura, Takeshi; Matz, Joachim M; Kenthirapalan, Sanketha; Kooij, Taco W A; Matuschewski, Kai; van Gemert, Geert-Jan; van de Vegte-Bolmer, Marga; Siebelink-Stoter, Rianne; Graumans, Wouter; Ramesar, Jai; Klop, Onny; Russel, Frans G M; Sauerwein, Robert W; Janse, Chris J; Franke-Fayard, Blandine M; Koenderink, Jan B

    2016-07-01

    Multidrug resistance (MDR) proteins belong to the B subfamily of the ATP Binding Cassette (ABC) transporters, which export a wide range of compounds including pharmaceuticals. In this study, we used reverse genetics to study the role of all seven Plasmodium MDR proteins during the life cycle of malaria parasites. Four P. berghei genes (encoding MDR1, 4, 6 and 7) were refractory to deletion, indicating a vital role during blood stage multiplication and validating them as potential targets for antimalarial drugs. Mutants lacking expression of MDR2, MDR3 and MDR5 were generated in both P. berghei and P. falciparum, indicating a dispensable role for blood stage development. Whereas P. berghei mutants lacking MDR3 and MDR5 had a reduced blood stage multiplication in vivo, blood stage growth of P. falciparum mutants in vitro was not significantly different. Oocyst maturation and sporozoite formation in Plasmodium mutants lacking MDR2 or MDR5 was reduced. Sporozoites of these P. berghei mutants were capable of infecting mice and life cycle completion, indicating the absence of vital roles during liver stage development. Our results demonstrate vital and dispensable roles of MDR proteins during blood stages and an important function in sporogony for MDR2 and MDR5 in both Plasmodium species. PMID:26991313

  6. Use of Six Sigma to improve pharmacist dispensing errors at an outpatient clinic.

    Chan, Agnes L F

    2004-01-01

    Hospital pharmacists have been challenged to face the paradigm shift in their model of services in the 21st century in Taiwan. Patients are increasingly concerned about drug safety and medication errors. Because of the financial crisis of our national insurance bureau, pharmacists are required to care for more patients, use fewer resources, and work faster, better, and more efficiently than ever before while striving to enhance customer satisfaction and quality of care. Under these circumstances, patient safety needs to be a priority of pharmacists. According to a preliminary report on medication error announced by the nonofficial medication error reporting system, pharmacist dispensing error ranked second in the list of errors in Taiwan. In our drive to improve quality, reduce costs, and enhance financial performance, our department has tried the traditional quality-improvement strategy with varying degrees of success. We wanted to achieve a breakthrough result, hence we implemented Six-Sigma methodology. This program is the catalyst needed to combine quality, cost, and patient safety. This article describes our experience using Six-Sigma methodology to reduce dispensing error in our pharmacy department. PMID:15212318

  7. Acoustic Center or Time Origin?

    Staffeldt, Henrik

    1999-01-01

    The paper discusses the acoustic center in relation to measurements of loudspeaker polar data. Also, it presents the related concept time origin and discusses the deviation that appears between positions of the acoustic center found by wavefront based and time based measuring methods....

  8. Propagation of Ion Acoustic Perturbations

    Pécseli, Hans

    1975-01-01

    Equations describing the propagation of ion acoustic perturbations are considered, using the assumption that the electrons are Boltzman distributed and isothermal at all times. Quasi-neutrality is also considered.......Equations describing the propagation of ion acoustic perturbations are considered, using the assumption that the electrons are Boltzman distributed and isothermal at all times. Quasi-neutrality is also considered....

  9. Acoustic Metamaterials and Phononic Crystals

    2013-01-01

    This comprehensive book presents all aspects of acoustic metamaterials and phononic crystals. The emphasis is on acoustic wave propagation phenomena at interfaces such as refraction, especially unusual refractive properties and negative refraction. A thorough discussion of the mechanisms leading to such refractive phenomena includes local resonances in metamaterials and scattering in phononic crystals.

  10. Digital Controller For Acoustic Levitation

    Tarver, D. Kent

    1989-01-01

    Acoustic driver digitally controls sound fields along three axes. Allows computerized acoustic levitation and manipulation of small objects for such purposes as containerless processing and nuclear-fusion power experiments. Also used for controlling motion of vibration-testing tables in three dimensions.

  11. Wavelet-based acoustic emission detection method with adaptive thresholding

    Menon, Sunil; Schoess, Jeffrey N.; Hamza, Rida; Busch, Darryl

    2000-06-01

    Reductions in Navy maintenance budgets and available personnel have dictated the need to transition from time-based to 'condition-based' maintenance. Achieving this will require new enabling diagnostic technologies. One such technology, the use of acoustic emission for the early detection of helicopter rotor head dynamic component faults, has been investigated by Honeywell Technology Center for its rotor acoustic monitoring system (RAMS). This ambitious, 38-month, proof-of-concept effort, which was a part of the Naval Surface Warfare Center Air Vehicle Diagnostics System program, culminated in a successful three-week flight test of the RAMS system at Patuxent River Flight Test Center in September 1997. The flight test results demonstrated that stress-wave acoustic emission technology can detect signals equivalent to small fatigue cracks in rotor head components and can do so across the rotating articulated rotor head joints and in the presence of other background acoustic noise generated during flight operation. This paper presents the results of stress wave data analysis of the flight-test dataset using wavelet-based techniques to assess background operational noise vs. machinery failure detection results.

  12. Recent Advances in Underwater Acoustic Modelling and Simulation

    ETTER, P. C.

    2001-02-01

    A comprehensive review of international developments in underwater acoustic modelling is used to construct an updated technology baseline containing 107 propagation models, 16 noise models, 17 reverberation models and 25 sonar performance models. This updated technology baseline represents a 30% increase over a previous baseline published in 1996. When executed in higher-level simulations, these models can generate predictive and diagnostic outputs that are useful to acoustical oceanographers or sonar technologists in the analysis of complex systems operating in the undersea environment. Recent modelling developments described in the technical literature suggest two principal areas of application: low-frequency, inverse acoustics in deep water; and high-frequency, bottom-interacting acoustics in coastal regions. Rapid changes in global geopolitics have opened new avenues for collaboration, thereby facilitating the transfer of modelling and simulation technologies among members of the international community. This accelerated technology transfer has created new imperatives for international standards in modelling and simulation architectures. National and international activities to promote interoperability among modelling and simulation efforts in government, industry and academia are reviewed and discussed.

  13. Acoustic array systems theory, implementation, and application

    Bai, Mingsian R; Benesty, Jacob

    2013-01-01

    Presents a unified framework of far-field and near-field array techniques for noise source identification and sound field visualization, from theory to application. Acoustic Array Systems: Theory, Implementation, and Application provides an overview of microphone array technology with applications in noise source identification and sound field visualization. In the comprehensive treatment of microphone arrays, the topics covered include an introduction to the theory, far-field and near-field array signal processing algorithms, practical implementations, and common applic

  14. Prescription of potentially inappropriate medication in older persons in Switzerland: does the dispensing channel make a difference?

    Blozik E

    2015-04-01

    Full Text Available Eva Blozik,1,2 Roland Rapold,1 Oliver Reich1 1Department of Health Sciences, Helsana Group, Zürich, Switzerland; 2Department of Medicine, Division of General Practice, University Medical Centre Freiburg, Freiburg, Germany Background: Drugs can be supplied either directly from the prescribing physician (physician dispensing [PD] or via a pharmacy. It is unclear whether the dispensing channel is associated with quality problems. Potentially inappropriate medication (PIM is associated with adverse outcomes in older persons and can be considered a marker for quality deficits in prescribing. We investigated whether prevalence of PIM differs across dispensing channels. Patients and methods: We analyzed basic health insurance claims of 50,747 person quarter years with PIM use of residents of the Swiss cantons Aargau and Lucerne of the years 2012 and 2013. PIM was identified using the Beers 2012 criteria and the PRISCUS list. We calculated PIM prevalence stratified by supply channel. Adjusted mixed effects logistic regression analysis was done to estimate the effect of obtaining medications through the dispensing physician as compared to the pharmacy channel on receipt of PIM. The most frequent PIMs were identified. Results: There is a small but detectable difference in total PIM prevalence: 30.7% of the population supplied by a dispensing physician as opposed to 29.3% individuals who received medication in a pharmacy. According to adjusted logistic regression individuals who obtained the majority of their medications from their prescribing physician had a 15% higher chance to receive a PIM (odds ratio 1.15, 95% confidence interval 1.08–1.22; P<0.001. Conclusion: Physician dispensing seems to affect quality and safety of drug prescriptions. Quality issues should not be neglected in the political discussion about the regulations on PD. Future studies should explore whether PD is related to other indicators of inefficiency or quality flaws. The present

  15. Collimated, single-pass atom source from a pulsed alkali metal dispenser for laser-cooling experiments

    We have developed an improved scheme for loading atoms into a magneto-optical trap (MOT) from a directed rubidium alkali metal dispenser in -10 Torr ultrahigh vacuum conditions. A current-driven dispenser was surrounded with a cold absorbing 'shroud' held at ≤0 deg. C, pumping rubidium atoms not directed into the MOT. This nearly eliminates background atoms and reduces the detrimental rise in pressure normally associated with these devices. The system can be well-described as a current-controlled, rapidly switched, two-temperature thermal beam, and was used to load a MOT with 3x108 atoms

  16. MEMS Based Acoustic Array

    Sheplak, Mark (Inventor); Nishida, Toshikaza (Inventor); Humphreys, William M. (Inventor); Arnold, David P. (Inventor)

    2006-01-01

    Embodiments of the present invention described and shown in the specification aid drawings include a combination responsive to an acoustic wave that can be utilized as a dynamic pressure sensor. In one embodiment of the present invention, the combination has a substrate having a first surface and an opposite second surface, a microphone positioned on the first surface of the substrate and having an input and a first output and a second output, wherein the input receives a biased voltage, and the microphone generates an output signal responsive to the acoustic wave between the first output and the second output. The combination further has an amplifier positioned on the first surface of the substrate and having a first input and a second input and an output, wherein the first input of the amplifier is electrically coupled to the first output of the microphone and the second input of the amplifier is electrically coupled to the second output of the microphone for receiving the output sinual from the microphone. The amplifier is spaced from the microphone with a separation smaller than 0.5 mm.

  17. Acoustics and Hearing

    Damaske, Peter

    2008-01-01

    When one listens to music at home, one would like to have an acoustic impression close to that of being in the concert hall. Until recently this meant elaborate multi-channelled sound systems with 5 or more speakers. But head-related stereophony achieves the surround-sound effect in living rooms with only two loudspeakers. By virtue of their slight directivity as well as an electronic filter the limitations previously common to two-speaker systems can be overcome and this holds for any arbitrary two-channel recording. The book also investigates the question of how a wide and diffuse sound image can arise in concert halls and shows that the quality of concert halls decisively depends on diffuse sound images arising in the onset of reverberation. For this purpose a strong onset of reverberation is modified in an anechoic chamber by electroacoustic means. Acoustics and Hearing proposes ideas concerning signal processing in the auditory system that explain the measured results and the resultant sound effects plea...

  18. Musical acoustics demonstrations

    Hoekje, P. L.

    2003-10-01

    The ASA Musical Acoustics Demonstrations website (trial version at http://www.bw.edu/~phoekje) includes sound files, video clips, program code listings, and other material for demonstrations related to musical acoustics. Many of the sound demonstrations may be experienced either as expositions, in which the phenomena are explained before they are presented, or as experiments, in which the explanation comes after listeners have had the opportunity to draw their own conclusions. Suggestions are provided for apparatus construction and classroom experiments, as well as for building simple musical instruments. Software is recommended if it is available free and compatible with multiple personal computer operating systems. For example, Audacity (http://audacity.sourceforce.net) is a sound file editor and analyzer that can be used to visually represent sounds and manipulate them. Source files are included for the synthesized sound examples, which were created in Csound (http://csounds.com), so that interested users may create their own variations. Source code is also included for visual demonstrations created in Visual Python and Python (http://www.python.org), an efficient, high level programming language. Suggestions, criticisms, and contributions are always welcome! [Work supported by ASA and Baldwin-Wallace College.

  19. Time-reversal acoustics

    Fink, Mathias [Laboratoire Ondes et Acoustique, Ecole Superieure de Physique et de Chimie Industrielle de la Ville de Paris, Universite Denis Diderot, UMR CNRS 7587, 10 Rue Vauquelin, 75005 Paris (France)], E-mail: mathias.fink@espci.fr

    2008-10-15

    Time-reversal mirrors (TRMs) refocus an incident acoustic field to the position of the original source regardless of the complexity of the propagation medium. TRM's have now been implemented in a variety of physical scenarios from MHz ultrasonics with order centimeter aperture size to hundreds/thousands of Hz in ocean acoustics with order hundred meter aperture size. Common to this broad range of scales is a remarkable robustness exemplified by observations at all scales that the more complex the medium between the probe source and the TRM, the sharper the focus. The relation between the medium complexity and the size of the focal spot is studied in this paper. It is certainly the most exciting property of TRM compared to standard focusing devices. A TRM acts as an antenna that uses complex environments to appears wider than it is, resulting for a broadband pulse in a refocusing quality that does not depend of the TRM aperture. In this paper, we investigate the time-reversal approach in various media of increasing complexity and we discuss the link existing between time-reversal approach and local helioseismology where Green's functions can be extracted from diffusive noise.

  20. Acoustic Absorption in Porous Materials

    Kuczmarski, Maria A.; Johnston, James C.

    2011-01-01

    An understanding of both the areas of materials science and acoustics is necessary to successfully develop materials for acoustic absorption applications. This paper presents the basic knowledge and approaches for determining the acoustic performance of porous materials in a manner that will help materials researchers new to this area gain the understanding and skills necessary to make meaningful contributions to this field of study. Beginning with the basics and making as few assumptions as possible, this paper reviews relevant topics in the acoustic performance of porous materials, which are often used to make acoustic bulk absorbers, moving from the physics of sound wave interactions with porous materials to measurement techniques for flow resistivity, characteristic impedance, and wavenumber.

  1. Acoustic monitoring method and device

    The present invention provides a method of eliminating resonance noises upon acoustically monitoring the operation state of power plants and plant equipments whether they are normal or not, to improve sensitivity for detecting abnormalities. Namely, a microphone detects acoustic signals including leaking sounds and converts them into electric signals. An amplifier amplifies the electric signals to an appropriate level. A noise eliminating section eliminates resonance noises other than the leaking sounds. An abnormality judging section judges presence of abnormality based on the level of the acoustic signals of the leaking sounds. With such a constitution, a plurality of resonance noises generated also during normal plant operation are automatically eliminated. Since resonance noises as a factor of lowering the sensitivity for abnormal sound detection are not included in the acoustic signals, the sensitivity for the abnormal sound detection is improved. Accordingly, the performance of the acoustic monitoring device is improved. (I.S.)

  2. 声发射技术在钢包耳轴环形焊缝安全检测中的应用%On the way to safety detect the circumferential welds for a steel ladle trunnion by using the acoustic emission technology

    张维刚; 徐彦廷; 王强; 叶荣耀; 何鹏君

    2013-01-01

    钢包耳轴焊缝缺陷是影响钢包安全运行的重大危险源,常规检测手段无法探测耳轴根部的疲劳裂纹.利用声发射平面定位技术对钢包耳轴焊缝进行检测,对检测数据进行滤波,以确定目标信号.利用希尔伯特-黄变换对目标信号进行EMD分解,对分解后的8个本征模态函数进行傅里叶变换,以确定其频率范围.结果表明,声发射技术对形状复杂的大型设备的结构完整性检测有独特优势.%The present paper is to introduce a method on how to detect the circumferential welding defects for a steel ladle trunnion by using the acoustic emission technology.As is known,ladles are essential part to move liquid metals at high temperature in metallurgical works.However,the defects in trunnion welds of a steel ladle always tend to be major hazard sources leading to the safe operation of the ladles.But the conventional detection method can hardly find the fatigue cracks in the trunnion root.It is for this reason that we have been working at the problem and proposed a scheme that acoustic emission plannar location technology can be used for the job in this paper.The given method we have developed can be used to examine the behavior of material deformation under stress by using the Acoustic Emission (AE) testing,which can be used as a nondestructive means for finding the defects in the structural proof testing and plant operation.Our method is to use the SAMOS AE system,in which the testing device is a technologically advanced system based on PAC's PCI -8 Acoustic Emission and can be made highly exciting or stimulating.The method has been developed working at a low power,low bandwidth and multiple channels.The SAMOS AE system we have proposed is working through the process of collecting incoming hits into events & analyzing the entering times of the hits in an event to produce a source location.In the process,the data filtering has been done to find the target signals.The results of

  3. New Cubic Cross filter detector for multi beam data recorded with DIDSON acoustic camera

    Balk, H.; Lindem, T.; Kubečka, Jan

    Heraklion : Foundation for Research & Technology, 2009 - (Papadakis, J.; Bjorno, L.), s. 1461-1468 ISBN 978-960-98883-3-2. [Underwater acoustic measurements, Technologies & Results. Nafplion (GR), 21.06.2009-27.06.2009] R&D Projects: GA ČR(CZ) GA206/07/1392 Institutional research plan: CEZ:AV0Z60170517 Keywords : fish tracking * fish detection Subject RIV: BI - Acoustics

  4. Failure Mechanism of Rock Bridge Based on Acoustic Emission Technique

    Guoqing Chen; Yan Zhang; Runqiu Huang; Fan Guo; Guofeng Zhang

    2015-01-01

    Acoustic emission (AE) technique is widely used in various fields as a reliable nondestructive examination technology. Two experimental tests were carried out in a rock mechanics laboratory, which include (1) small scale direct shear tests of rock bridge with different lengths and (2) large scale landslide model with locked section. The relationship of AE event count and record time was analyzed during the tests. The AE source location technology and comparative analysis with its actual failu...

  5. Acoustic tests of Lorentz symmetry using Bulk Acoustic Wave quartz oscillators

    Goryachev, M; Haslinger, Ph; Mizrachi, E; Anderegg, L; Müller, H; Hohensee, M; Tobar, M E

    2016-01-01

    A new method of probing Lorentz invariance in the neutron sector is described. The method is baed on stable quartz bulk acoustic wave oscillators compared on a rotating table. Due to Lorentz-invariance violation, the resonance frequencies of acoustic wave resonators depend on the direction in space via a corresponding dependence of masses of the constituent elements of solids. This dependence is measured via observation of oscillator phase noise built around such devices. The first such experiment now shows sensitivity to violation down to the limit $\\tilde{c}^n_Q=(-1.8\\pm2.2)\\times 10^{-14}$ GeV. Methods to improve the sensitivity are described together with some other applications of the technology in tests of fundamental physics.

  6. Polymer Optical Fibre Sensors for Endoscopic Opto-Acoustic Imaging

    Broadway, Christian; Gallego, Daniel; Woyessa, Getinet;

    2015-01-01

    Opto-acoustic imaging (OAI) shows particular promise for in-vivo biomedical diagnostics. Its applications include cardiovascular, gastrointestinal and urogenital systems imaging. Opto-acoustic endoscopy (OAE) allows the imaging of body parts through cavities permitting entry. The critical parameter...... in existing publications. A great advantage can be obtained for endoscopy due to a small size and array potential to provide discrete imaging speed improvements. Optical fibre exhibits numerous advantages over conventional piezo-electric transducers, such as immunity from electromagnetic interference...... on the opportunities and challenges of applying this technology in biomedical applications....

  7. Experimental verification of theoretical equations for acoustic radiation force on compressible spherical particles in traveling waves

    Johnson, Kennita A.; Vormohr, Hannah R.; Doinikov, Alexander A.; Bouakaz, Ayache; Shields, C. Wyatt; López, Gabriel P.; Dayton, Paul A.

    2016-05-01

    Acoustophoresis uses acoustic radiation force to remotely manipulate particles suspended in a host fluid for many scientific, technological, and medical applications, such as acoustic levitation, acoustic coagulation, contrast ultrasound imaging, ultrasound-assisted drug delivery, etc. To estimate the magnitude of acoustic radiation forces, equations derived for an inviscid host fluid are commonly used. However, there are theoretical predictions that, in the case of a traveling wave, viscous effects can dramatically change the magnitude of acoustic radiation forces, which make the equations obtained for an inviscid host fluid invalid for proper estimation of acoustic radiation forces. To date, experimental verification of these predictions has not been published. Experimental measurements of viscous effects on acoustic radiation forces in a traveling wave were conducted using a confocal optical and acoustic system and values were compared with available theories. Our results show that, even in a low-viscosity fluid such as water, the magnitude of acoustic radiation forces is increased manyfold by viscous effects in comparison with what follows from the equations derived for an inviscid fluid.

  8. PORTABLE ACOUSTIC MONITORING PACKAGE (PAMP)

    John L. Loth; Gary J. Morris; George M. Palmer; Richard Guiler; Patrick Browning

    2004-07-20

    The Portable Acoustic Monitoring Package (PAMP) has been designed to record and monitor the acoustic signal in natural gas transmission lines. In particular the three acoustic signals associated with a line leak. The system is portable ({approx}30 lbs) and is designed for line pressures up to 1000 psi. It has become apparent that cataloging of the various background acoustic signals in natural gas transmission line is very important if a system to identify leak signals is to be developed. The low-pressure (0-200 psig) laboratory test phase has been completed and a number of field trials have been conducted. Before the cataloging phase could begin, a few problems identified in field trials identified had to be corrected such as: (1) Decreased microphone sensitivity at line pressures above 250 psig. (2) The inability to deal with large data sets collected when cataloging the variety of signals in a transmission line. (3) The lack of an available online acoustic calibration system. These problems have been solved and the WVU PAMP is now fully functional over the entire pressure range found in the Natural Gas transmission lines in this region. Field portability and reliability have been greatly improved. Data collection and storage have also improved to the point were the full acoustic spectrum of acoustic signals can be accurately cataloged, recorded and described.

  9. Controlling sound with acoustic metamaterials

    Cummer, Steven A.; Christensen, Johan; Alù, Andrea

    2016-03-01

    Acoustic metamaterials can manipulate and control sound waves in ways that are not possible in conventional materials. Metamaterials with zero, or even negative, refractive index for sound offer new possibilities for acoustic imaging and for the control of sound at subwavelength scales. The combination of transformation acoustics theory and highly anisotropic acoustic metamaterials enables precise control over the deformation of sound fields, which can be used, for example, to hide or cloak objects from incident acoustic energy. Active acoustic metamaterials use external control to create effective material properties that are not possible with passive structures and have led to the development of dynamically reconfigurable, loss-compensating and parity-time-symmetric materials for sound manipulation. Challenges remain, including the development of efficient techniques for fabricating large-scale metamaterial structures and converting laboratory experiments into useful devices. In this Review, we outline the designs and properties of materials with unusual acoustic parameters (for example, negative refractive index), discuss examples of extreme manipulation of sound and, finally, provide an overview of future directions in the field.

  10. Surface Acoustic Wave Devices

    Dühring, Maria Bayard

    The work of this project is concerned with the simulation of surface acoustic waves (SAW) and topology optimization of SAW devices. SAWs are elastic vibrations that propagate along a material surface and are extensively used in electromechanical filters and resonators in telecommunication. A new...... application is modulation of optical waves in waveguides. This presentation elaborates on how a SAW is generated by interdigital transducers using a 2D model of a piezoelectric, inhomogeneous material implemented in the high-level programming language Comsol Multiphysics. The SAW is send through a model of a...... output waveguide and the MZI can thus be used as an optical switch. It is explained how the mechanical model of the SAW is coupled to a model of the optical waves such that the change in effective refractive index introduced in the MZI arms by the SAW can be calculated. Results of a parameter study of...

  11. Evoked acoustic emission

    Elberling, C; Parbo, J; Johnsen, N J;

    1985-01-01

    Stimulated acoustic emissions were recorded in response to tonal stimuli at 60 dB p.e. SPL in a small group of normal-hearing adults. Power spectral analysis reveals that the evoked activity from each ear contains energy in preferential frequency bands and the change of stimulus frequency has only...... a minor effect on the power spectra, i.e. the maximum jumps from one spectral peak to another. Experiments with deconvolution demonstrate that the emission generating system at least at a fixed intensity can be regarded as being linear and characterized by its impulse response which is similar to...... the emission evoked by click stimuli. It is concluded that significant information is obtained by the click rather than by the tonal stimuli. The click-evoked emissions were also recorded from both ears in a consecutive series of 100 full-term and otherwise normal babies 2-4 days after birth. The...

  12. Acoustic emission testing

    Grosse, Christian U

    2008-01-01

    Acoustic Emission (AE) techniques have been studied in civil engineering for a long time. The techniques are recently going to be more and more applied to practical applications and to be standardized in the codes. This is because the increase of aging structures and disastrous damages due to recent earthquakes urgently demand for maintenance and retrofit of civil structures in service for example. It results in the need for the development of advanced and effective inspection techniques. Thus, AE techniques draw a great attention to diagnostic applications and in material testing. The book covers all levels from the description of AE basics for AE beginners (level of a student) to sophisticated AE algorithms and applications to real large-scale structures as well as the observation of the cracking process in laboratory specimen to study fracture processes.

  13. Acoustic emission: The first half century

    Drouillard, T.F.

    1994-08-01

    The technology of acoustic emission (AE) is approaching the half century mark, having had its beginning in 1950 with the work of Joseph Kaiser. During the 1950s and 1960s researchers delved into the fundamentals of acoustic emission, developed instrumentation specifically for AE, and characterized the AE behavior of many materials. AE was starting to be recognized for its unique capabilities as an NDT method for monitoring dynamic processes. In the decade of the 1970s research activities became more coordinated and directed with the formation of the working groups, and its use as an NDT method continued to increase for industrial applications. In the 1980s the computer became a basic component for both instrumentation and data analysis, and today it has sparked a resurgence of opportunities for research and development. Today we are seeing a transition to waveform-based AE analysis and a shift in AE activities with more emphasis on applications than on research. From the beginning, we have been fortunate to have had so many dedicated savants with different fields of expertise contribute in a collective way to bring AE to a mature, fully developed technology and leave a legacy of knowledge recorded in its literature. AE literature has been a key indicator of the amount of activity, the proportion of research to application, the emphasis on what was of current interest, and the direction AE has taken. The following is a brief survey of the history of acoustic emission with emphasis on development of the infrastructure over the past half century.

  14. Acoustic emission: The first half century

    Drouillard, Thomas F.

    The technology of acoustic emission (AE) is approaching the half century mark, having had its beginning in 1950 with the work of Joseph Kaiser. During the 1950s and 1960s researchers delved into the fundamentals of acoustic emission, developed instrumentation specifically for AE, and characterized the AE behavior of many materials. AE was starting to be recognized for its unique capabilities as an NDT method for monitoring dynamic processes. In the decade of the 1970s research activities became more coordinated and directed with the formation of the working groups, and its use as an NDT method continued to increase for industrial applications. In the 1980s the computer became a basic component for both instrumentation and data analysis, and today it has sparked a resurgence of opportunities for research and development. Today we are seeing a transition to waveform-based AE analysis and a shift in AE activities with more emphasis on applications than on research. From the beginning, we have been fortunate to have had so many dedicated savants with different fields of expertise contribute in a collective way to bring AE to a mature, fully developed technology and leave a legacy of knowledge recorded in its literature. AE literature has been a key indicator of the amount of activity, the proportion of research to application, the emphasis on what was of current interest, and the direction AE has taken. The following is a brief survey of the history of acoustic emission with emphasis on development of the infrastructure over the past half century.

  15. An asymptotic model in acoustics:acoustic drift equations

    Vladimirov, Vladimir; Ilin, Konstantin

    2013-01-01

    A rigorous asymptotic procedure with the Mach number as a small parameter is used to derive the equations of mean flows which coexist and are affected by the background acoustic waves in the limit of very high Reynolds number.

  16. Anisotropic spectra of acoustic turbulence

    We found universal anizopropic spectra of acoustic turbulence with the linear dispersion law ω(k)=ck within the framework of generalized kinetic equation which takes into account the finite time of three-wave interactions. This anisotropic spectra can assume both scale-invariant and non-scale-invariant form. The implications for the evolution of the acoustic turbulence with nonisotropic pumping are discussed. The main result of the article is that the spectra of acoustic turbulence tend to become more isotropic. (c) 2000 The American Physical Society

  17. Theoretical acoustics of underwater structures

    Skelton, EA

    1997-01-01

    This important book provides an account of the linear acoustics of basic isotropic/anisotropic structures excited by time-harmonic and transient mechanical forces and acoustic sources. Many numerical examples are given to aid physical insight and to provide benchmark computations of sound radiation and sound scattering. The theoretical methods, developed originally for naval noise control problems, should find civil application in the acoustic modelling of structures fabricated from both fibre-reinforced and isotropic materials. Such an endeavour is increasingly desirable and necessary in this

  18. Acoustic metamaterial with negative density

    We fabricated a one-dimensional acoustic metamaterial with negative effective density using an array of very thin elastic membranes. We observed acoustic equivalence of the plasma oscillation at ωc=735 Hz. The metamaterial was opaque in the frequency range from 0 to 735 Hz, and was transparent above 735 Hz. We report direct observation of negative acceleration in this acoustic medium below 735 Hz. The frequency characteristics of the metamaterial have the same form as that of metals with negative permittivity. We also provide a simple theory to explain the experimental results.

  19. Noise Shielding Using Acoustic Metamaterials

    We exploit theoretically a class of rectangular cylindrical devices for noise shielding by using acoustic metamaterials. The function of noise shielding is justified by both the far-field and near-field full-wave simulations based on the finite element method. The enlargement of equivalent acoustic scattering cross sections is revealed to be the physical mechanism for this function. This work makes it possible to design a window with both noise shielding and air flow. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  20. Acoustic metamaterial with negative modulus

    We present experimental and theoretical results on an acoustic metamaterial that exhibits a negative effective modulus in a frequency range from 0 to 450 Hz. A one-dimensional acoustic metamaterial with an array of side holes on a tube was fabricated. We observed that acoustic waves above 450 Hz propagated well in this structure, but no sound below 450 Hz passed through. The frequency characteristics of the metamaterial has the same form as that of the permittivity in metals due to the plasma oscillation. We also provide a theory to explain the experimental results.

  1. Electrically Controllable Microparticle Synthesis and Digital Microfluidic Manipulation by Electric-Field-Induced Droplet Dispensing into Immiscible Fluids

    Um, Taewoong; Hong, Jiwoo; Im, Do Jin; Lee, Sang Joon; Kang, In Seok

    2016-01-01

    The dispensing of tiny droplets is a basic and crucial process in a myriad of applications, such as DNA/protein microarray, cell cultures, chemical synthesis of microparticles, and digital microfluidics. This work systematically demonstrates droplet dispensing into immiscible fluids through electric charge concentration (ECC) method. It exhibits three main modes (i.e., attaching, uniform, and bursting modes) as a function of flow rates, applied voltages, and gap distances between the nozzle and the oil surface. Through a conventional nozzle with diameter of a few millimeters, charged droplets with volumes ranging from a few μL to a few tens of nL can be uniformly dispensed into the oil chamber without reduction in nozzle size. Based on the features of the proposed method (e.g., formation of droplets with controllable polarity and amount of electric charge in water and oil system), a simple and straightforward method is developed for microparticle synthesis, including preparation of colloidosomes and fabrication of Janus microparticles with anisotropic internal structures. Finally, a combined system consisting of ECC-induced droplet dispensing and electrophoresis of charged droplet (ECD)-driven manipulation systems is constructed. This integrated platform will provide increased utility and flexibility in microfluidic applications because a charged droplet can be delivered toward the intended position by programmable electric control. PMID:27534580

  2. Electrically Controllable Microparticle Synthesis and Digital Microfluidic Manipulation by Electric-Field-Induced Droplet Dispensing into Immiscible Fluids.

    Um, Taewoong; Hong, Jiwoo; Im, Do Jin; Lee, Sang Joon; Kang, In Seok

    2016-01-01

    The dispensing of tiny droplets is a basic and crucial process in a myriad of applications, such as DNA/protein microarray, cell cultures, chemical synthesis of microparticles, and digital microfluidics. This work systematically demonstrates droplet dispensing into immiscible fluids through electric charge concentration (ECC) method. It exhibits three main modes (i.e., attaching, uniform, and bursting modes) as a function of flow rates, applied voltages, and gap distances between the nozzle and the oil surface. Through a conventional nozzle with diameter of a few millimeters, charged droplets with volumes ranging from a few μL to a few tens of nL can be uniformly dispensed into the oil chamber without reduction in nozzle size. Based on the features of the proposed method (e.g., formation of droplets with controllable polarity and amount of electric charge in water and oil system), a simple and straightforward method is developed for microparticle synthesis, including preparation of colloidosomes and fabrication of Janus microparticles with anisotropic internal structures. Finally, a combined system consisting of ECC-induced droplet dispensing and electrophoresis of charged droplet (ECD)-driven manipulation systems is constructed. This integrated platform will provide increased utility and flexibility in microfluidic applications because a charged droplet can be delivered toward the intended position by programmable electric control. PMID:27534580

  3. Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses.

    Jang Eun Lee

    Full Text Available Differentiation of T cells is closely associated with dynamic changes in nutrient and energy metabolism. However, the extent to which specific metabolic pathways and molecular components are determinative of CD8+ T cell fate remains unclear. It has been previously established in various tissues that acetyl CoA carboxylase 2 (ACC2 regulates fatty acid oxidation (FAO by inhibiting carnitine palmitoyltransferase 1 (CPT1, a rate-limiting enzyme of FAO in mitochondria. Here, we explore the cell-intrinsic role of ACC2 in T cell immunity in response to infections. We report here that ACC2 deficiency results in a marginal increase of cellular FAO in CD8+ T cells, but does not appear to influence antigen-specific effector and memory CD8+ T cell responses during infection with listeria or lymphocytic choriomeningitis virus. These results suggest that ACC2 is dispensable for CD8+ T cell responses.

  4. The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

    Malivert, Laurent; Callebaut, Isabelle; Rivera-Munoz, Paola; Fischer, Alain; Mornon, Jean-Paul; Revy, Patrick; de Villartay, Jean-Pierre

    2009-03-01

    The core nonhomologous end-joining DNA repair pathway is composed of seven factors: Ku70, Ku80, DNA-PKcs, Artemis, XRCC4 (X4), DNA ligase IV (L4), and Cernunnos/XLF (Cernunnos). Although Cernunnos and X4 are structurally related and participate in the same complex together with L4, they have distinct functions during DNA repair. L4 relies on X4 but not on Cernunnos for its stability, and L4 is required for optimal interaction of Cernunnos with X4. We demonstrate here, using in vitro-generated Cernunnos mutants and a series of functional assays in vivo, that the C-terminal region of Cernunnos is dispensable for its activity during DNA repair. PMID:19103754

  5. Correlation between microstructure and thermionic electron emission from Os-Ru thin films on dispenser cathodes

    Osmium-ruthenium films with different microstructures were deposited onto dispenser cathodes and subjected to 1000 h of close-spaced diode testing. Tailored microstructures were achieved by applying substrate biasing during deposition, and these were evaluated with scanning electron microscopy, x-ray diffraction, and energy dispersive x-ray spectroscopy before and after close-spaced diode testing. Knee temperatures determined from the close-spaced diode test data were used to evaluate cathode performance. Cathodes with a large (10-11) Os-Ru film texture possessed comparatively low knee temperatures. Furthermore, a low knee temperature correlated with a low effective work function as calculated from the close-spaced diode data. It is proposed that the formation of strong (10-11) texture is responsible for the superior performance of the cathode with a multilayered Os-Ru coating

  6. Investigation of Influence of Surface Nanoparticle on Emission Properties of Scandia-Doped Dispenser Cathodes

    Zhang, Xizhu; Wang, Jinshu; Wang, Yiman; Liu, Wei; Zhou, Meiling; Gao, Zhiyuan

    2013-08-01

    The microstructure of a fully activated scandia doped dispenser (SDD) cathode has been studied by scanning electron microscope (SEM). The observation results display that nanoparticles appear at the growth steps and the surface of tungsten grains of the fully activated SDD cathode. To study the influence of the nanoparticles on the emission, the local electric field strengths around the nanoparticles have been calculated by Maxwell 2D code and Comsol. The calculation results show that the local electric field strengths are enhanced by 1.1 to 3.8 times to average value based on different model conditions. The highest field strength is about 1.54 × 105 V/cm at an average field strength of 40 KV/cm, which is related to a space-charge limited (SCL) current density of 100 A/cm2 in the experimental configuration. This implies the field strength is not high enough to cause field emission.

  7. Correlation between microstructure and thermionic electron emission from Os-Ru thin films on dispenser cathodes

    Swartzentruber, Phillip D.; John Balk, Thomas, E-mail: john.balk@uky.edu [Department of Chemical and Materials Engineering, University of Kentucky, 177 F. Paul Anderson Tower, Lexington, Kentucky 40506-0046 (United States); Effgen, Michael P. [Semicon Associates, Lexington, Kentucky 40510 (United States)

    2014-07-01

    Osmium-ruthenium films with different microstructures were deposited onto dispenser cathodes and subjected to 1000 h of close-spaced diode testing. Tailored microstructures were achieved by applying substrate biasing during deposition, and these were evaluated with scanning electron microscopy, x-ray diffraction, and energy dispersive x-ray spectroscopy before and after close-spaced diode testing. Knee temperatures determined from the close-spaced diode test data were used to evaluate cathode performance. Cathodes with a large (10-11) Os-Ru film texture possessed comparatively low knee temperatures. Furthermore, a low knee temperature correlated with a low effective work function as calculated from the close-spaced diode data. It is proposed that the formation of strong (10-11) texture is responsible for the superior performance of the cathode with a multilayered Os-Ru coating.

  8. Some aspects of electron spectroscopic investigations of impregnated tungsten dispenser cathodes

    Impregnated tungsten dispenser cathodes from various manufacturers and of various impregnant compositions have been examined by several surface analytical techniques. In situ activation of these cathodes in UHV was studied using X-ray photoelectron spectroscopy, Auger electron spectroscopy and energy loss spectroscopy. Previous work on model compounds and structures of barium, oxygen and tungsten has been used to interpret the results, although no generally accepted conclusions could be drawn on the exact chemical states of the various elements present on an activated, operating cathode. The results presented will show that the measurements must be taken at temperature, and will demonstrate a method to overcome charging and other artifacts. In addition, the signature of a good cathode will be shown, which can be synthesized by adding standard barium metal on tungsten and barium on oxygen thin film spectra. (orig.)

  9. Scanning Auger and work-function measurements applied to dispenser cathodes

    A method fo perform spatially resolved work-function measurements has been developed using a modified scanning Auger microprobe (SAM). The method is based on patches of different work function giving rise to different onsets of secondary electron emission. The combined SAM work-function measurement permits a microscopic correlation of emissive or surface dipole properties with local elemental composition. The system offers a surface spatial resolution of 0.2 μm provided by the focused incident electron beam, and a work function resolution of better than 0.05 eV for most surface features of size approx. equal to 4.0 μm or larger. Results are presented for elemental samples which served as a test of the work-function mapping ability. Some initial results on dispenser cathode surfaces are also presented. (orig.)

  10. An electrode design for droplet dispensing with accurate volume in electro-wetting-based microfluidics

    Wang, Wei; Chen, Jianfeng; Zhou, Jia

    2016-06-01

    Electro-wetting-on-dielectric actuation enables droplets, the basic units of digital microfluidics, to be manipulated on a two-dimensional surface, providing a versatile platform for chemical assays or multi-step operations at micro- or nano-scale. In this paper, we carry out characterization experiments to demonstrate an electrode design to improve the reproducibility of on-chip droplet generation with no extra external apparatus. The overall reproducibility for a sequence of droplets dispensed consecutively from a non-refilling reservoir can be limited within ±0.5%. Results from the repetition of 1000 iterations offer the long-term reproducibility in the range of ±1%, indicating its validity in practical applications.

  11. Acoustic-optic investigations of acoustic gyrotropy in crystals

    For the experimental investigation of the acoustic activity the Bragg light diffraction method on transverse acoustic waves was used in the frequency range 0.4-1.8 GHz. It is shown that the oscillation period of the intensity of the diffracted light is defined by the specific rotator power of the crystal. On the basis of experimental data the specific rotation of the polarization plane in a number of gyrotropic crystals was determined. (authors)

  12. Fuel Cell Technologies Office FY 2017 Budget At-A-Glance

    None

    2016-03-01

    The Fuel Cell Technologies Office develops technologies to enable fuel cells to be competitive in diverse applications, with a focus on light-duty vehicles (at less than $40/kW) and to enable renewable hydrogen to be cost-competitive with gasoline (at less than $4 per gallon gasoline equivalent (gge), delivered and dispensed).

  13. Optically tunable acoustic wave band-pass filter

    N. Swinteck

    2014-12-01

    Full Text Available The acoustic properties of a hybrid composite that exhibits both photonic and phononic behavior are investigated numerically with finite-element and finite-difference time-domain simulations. The structure is constituted of a periodic array of photonic resonant cavities embedded in a background superlattice. The resonant cavities contain a photo-elastic chalcogenide glass that undergoes atomic-scale structural reorganization when irradiated with light having energy close to its band-gap. Photo-excitation of the chalcogenide glass changes its elastic properties and, consequently, augments the acoustic transmission spectrum of the composite. By modulating the intensity of light irradiating the hybrid photonic/phononic structure, the position and spectral width of phonon passing-bands can be controlled. This demonstration offers the technological platform for optically-tunable acoustic wave band-pass filters.

  14. Acoustic evaluation of cementing quality using obliquely incident ultrasonic signals

    Duan Wen-Xing; Qiao Wen-Xiao; Che Xiao-Hua; Xie Hui

    2014-01-01

    Ultrasonic cement bond logging is a widely used method for evaluating cementing quality. Conventional ultrasonic cement bond logging uses vertical incidence and cannot accurately evaluate lightweight cement bonding. Oblique incidence is a new technology for evaluating cement quality with improved accuracy for lightweight cements. In this study, we simulated models of acoustic impedance of cement and cementing quality using ultrasonic oblique incidence, and we obtained the relation between cementing quality, acoustic impedance of cement, and the acoustic attenuation coeffi cient of the A0-mode and S0-mode Lamb waves. Then, we simulated models of different cement thickness and we obtained the relation between cement thickness and the time difference of the arrival between the A0 and A0′ modes.

  15. Achieving acoustic cloak by using compressible background flow

    Zhang, Ruo-Yang; Zhao, Qing; Ge, Mo-Lin

    2016-08-01

    We propose a scheme of acoustic spherical cloaking by means of background irrotational flow in compressible fluid. The background flow forms a virtual curved spacetime and directs the sound waves to bypass the cloaked objects. To satisfy the laws of real fluid, we show that spatially distributed mass source and momentum source are necessary to supply. The propagation of sound waves in this system is studied via both geometric acoustics approximation and full wave approach. The analytic solution of sound fields is obtained for plane wave incidence. The results reveal the effect of phase retardation (or lead) in comparison with the ordinary transformation-acoustic cloak. In addition, the ability of cloaking is also evaluated for unideal background flows by analyzing the scattering cross section. Project supported by the National Natural Science Foundation of China (Grant Nos. 11475088 and 11275024) and the Fund from the Ministry of Science and Technology of China (Grant No. 2013YQ030595-3).

  16. Acoustic spectroscopy: A powerful analytical method for the pharmaceutical field?

    Bonacucina, Giulia; Perinelli, Diego R; Cespi, Marco; Casettari, Luca; Cossi, Riccardo; Blasi, Paolo; Palmieri, Giovanni F

    2016-04-30

    Acoustics is one of the emerging technologies developed to minimize processing, maximize quality and ensure the safety of pharmaceutical, food and chemical products. The operating principle of acoustic spectroscopy is the measurement of the ultrasound pulse intensity and phase after its propagation through a sample. The main goal of this technique is to characterise concentrated colloidal dispersions without dilution, in such a way as to be able to analyse non-transparent and even highly structured systems. This review presents the state of the art of ultrasound-based techniques in pharmaceutical pre-formulation and formulation steps, showing their potential, applicability and limits. It reports in a simplified version the theory behind acoustic spectroscopy, describes the most common equipment on the market, and finally overviews different studies performed on systems and materials used in the pharmaceutical or related fields. PMID:26976503

  17. Options for shielding the hand during dispensing and administration of radiopharmaceuticals

    Hospital staff manipulating radiopharmaceuticals may receive significant radiation doses to their hands. A study of hand doses has been carried out in a large radionuclide dispensary and in nuclear medicine departments in the West of Scotland and the implications of different shielding options considered. Doses received for individual manipulation during many routine sessions have been measured with an electronic extremity dose monitor. Doses received from dispensing of radiopharmaceuticals in nuclear medicine were 4 mGy per 10 GBq handled, compared to 0.2 mGy per 10 GBq for radionuclide dispensary staff. There were a number of reasons for the large difference, with one of the most important being the speed with which the manipulations were performed. The actions performed in nuclear medicine consist of dispensing into a syringe and injection. Withdrawal of radiopharmaceuticals made up the higher dose component 5 to 500 μSv per procedure as a siring shield was not used for this part of the procedure. Doses received from individual injections for which syringe shields were used varied from 1.5 to 300 μSv depending on the degree of difficulty experienced during the injection. The study has shown the effectiveness of using local shielding in dose reduction. Tungsten vial shields limit the radiation dose and are useful for handling large activities during radiopharmaceutical preparation. Syringe shields substantially reduce doses for individual manipulations and should be used for procedures in which accurate reading of the syringe scale is not required. This includes higher dose manipulations in the radionuclide dispensary and injections in nuclear medicine. (Author)

  18. Prelamin A and lamin A appear to be dispensable in the nuclear lamina.

    Fong, Loren G; Ng, Jennifer K; Lammerding, Jan; Vickers, Timothy A; Meta, Margarita; Coté, Nathan; Gavino, Bryant; Qiao, Xin; Chang, Sandy Y; Young, Stephanie R; Yang, Shao H; Stewart, Colin L; Lee, Richard T; Bennett, C Frank; Bergo, Martin O; Young, Stephen G

    2006-03-01

    Lamin A and lamin C, both products of Lmna, are key components of the nuclear lamina. In the mouse, a deficiency in both lamin A and lamin C leads to slow growth, muscle weakness, and death by 6 weeks of age. Fibroblasts deficient in lamins A and C contain misshapen and structurally weakened nuclei, and emerin is mislocalized away from the nuclear envelope. The physiologic rationale for the existence of the 2 different Lmna products lamin A and lamin C is unclear, although several reports have suggested that lamin A may have particularly important functions, for example in the targeting of emerin and lamin C to the nuclear envelope. Here we report the development of lamin C-only mice (Lmna(LCO/LCO)), which produce lamin C but no lamin A or prelamin A (the precursor to lamin A). Lmna(LCO/LCO) mice were entirely healthy, and Lmna(LCO/LCO) cells displayed normal emerin targeting and exhibited only very minimal alterations in nuclear shape and nuclear deformability. Thus, at least in the mouse, prelamin A and lamin A appear to be dispensable. Nevertheless, an accumulation of farnesyl-prelamin A (as occurs with a deficiency in the prelamin A processing enzyme Zmpste24) caused dramatically misshapen nuclei and progeria-like disease phenotypes. The apparent dispensability of prelamin A suggested that lamin A-related progeroid syndromes might be treated with impunity by reducing prelamin A synthesis. Remarkably, the presence of a single Lmna(LCO) allele eliminated the nuclear shape abnormalities and progeria-like disease phenotypes in Zmpste24-/- mice. Moreover, treating Zmpste24-/- cells with a prelamin A-specific antisense oligonucleotide reduced prelamin A levels and significantly reduced the frequency of misshapen nuclei. These studies suggest a new therapeutic strategy for treating progeria and other lamin A diseases. PMID:16511604

  19. Studies on the pressed yttrium oxide-tungsten matrix as a possible dispenser cathode material

    Yttrium oxide was chosen as the secondary emission substance based on calculation results through first principle theory method. A new kind of pressed yttrium oxide-tungsten matrix dispenser cathodes are prepared by a sol–gel method combined with high temperature sintering in dry hydrogen atmosphere. The results show that the growth of the grains is hampered by the pinning effect of Y2O3 distributing uniformly between the tungsten particles, resulting in the formation of small grain size. It is found that Y2O3 improves the secondary electron emission property, i.e., the secondary emission yield increases with the increase of Y2O3 content in the samples. The maximum secondary emission yield δmax of the cathode with 15% amount of Y2O3 can reach 2.92. Furthermore, the cathode shows a certain thermionic emission performance. The zero field emission current density J0 of 4.18A/cm2 has reached at 1050 °Cb for this kind of cathode after being activated at 1200 °Cb, which are much higher than that of rare earth oxide doped molybdenum (REO-Mo) cathode reported in the previous work. - Highlights: • Yttrium oxide was chosen as the secondary emission substance based on first principle calculation result. • A new kind of cathode has been successfully obtained. • Pressed yttrium oxide-tungsten matrix dispenser cathode exhibits good emission properties. • The improvement of the cathode emission can be well explained by the surface analysis results presented in this work

  20. Studies on the pressed yttrium oxide-tungsten matrix as a possible dispenser cathode material

    Yang, Fan; Wang, Jinshu, E-mail: wangjsh@bjut.edu.cn; Liu, Wei; Liu, Xiang; Zhou, Meiling

    2015-01-15

    Yttrium oxide was chosen as the secondary emission substance based on calculation results through first principle theory method. A new kind of pressed yttrium oxide-tungsten matrix dispenser cathodes are prepared by a sol–gel method combined with high temperature sintering in dry hydrogen atmosphere. The results show that the growth of the grains is hampered by the pinning effect of Y{sub 2}O{sub 3} distributing uniformly between the tungsten particles, resulting in the formation of small grain size. It is found that Y{sub 2}O{sub 3} improves the secondary electron emission property, i.e., the secondary emission yield increases with the increase of Y{sub 2}O{sub 3} content in the samples. The maximum secondary emission yield δ{sub max} of the cathode with 15% amount of Y{sub 2}O{sub 3} can reach 2.92. Furthermore, the cathode shows a certain thermionic emission performance. The zero field emission current density J{sub 0} of 4.18A/cm{sup 2} has reached at 1050 °C{sub b} for this kind of cathode after being activated at 1200 °C{sub b}, which are much higher than that of rare earth oxide doped molybdenum (REO-Mo) cathode reported in the previous work. - Highlights: • Yttrium oxide was chosen as the secondary emission substance based on first principle calculation result. • A new kind of cathode has been successfully obtained. • Pressed yttrium oxide-tungsten matrix dispenser cathode exhibits good emission properties. • The improvement of the cathode emission can be well explained by the surface analysis results presented in this work.