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Sample records for aco

  1. Pioneer ACO PUF

    U.S. Department of Health & Human Services — Pioneer ACO PUF - To address the increasing number of requests for Pioneer ACO data, the Centers for Medicare and Medicaid Services (CMS) has created a standard...

  2. Pioneer ACO Model

    U.S. Department of Health & Human Services — The Pioneer ACO Model is designed for health care organizations and providers that are already experienced in coordinating care for patients across care settings....

  3. Including Language Access into Medicaid ACO Design.

    Gershon, Rachel; Morris, Lisa; Ferguson, Warren

    2016-09-01

    Quality health care relies upon communication in a patient's preferred language. Language access in health care occurs when individuals are: (1) Welcomed by providers regardless of language ability; and (2) Offered quality language services as part of their care. Federal law generally requires access to health care and quality language services for deaf and Limited English Proficient (LEP) patients in health care settings, but these patients still find it hard to access health care and quality language services.Meanwhile, several states are implementing Medicaid Accountable Care Organization (ACO) initiatives to reduce health care costs and improve health care quality. Alternative payment methods used in these initiatives can give Accountable Care Organizations more flexibility to design linguistically accessible care, but they can also put ACOs at increased financial risk for the cost of care. If these new payment methods do not account for differences in patient language needs, ACO initiatives could have the unintended consequence of rewarding ACOs who do not reach out to deaf and LEP communities or offer quality language services.We reviewed public documents related to Medicaid ACO initiatives in six states. Some of these documents address language access. More could be done, however, to pay for language access efforts. This article describes Medicaid ACO initiatives and explores how different payment tools could be leveraged to reward ACOs for increased access to care and quality language services. We find that a combination of payment tools might be helpful to encourage both access and quality. PMID:27587453

  4. Recent results of the ACO storage ring

    A permanent magnet undulator has been built and installed on the ACO Storage Ring. The undulator design, the spontaneous emission and gain of the system, as well as the laser induced bunch lengthening of the electron bunch, are presented. A low-loss optical cavity has been also recently built and operated on the ring. Its performance and the degradation problems of the mirrors are discussed. Amplification of the spontaneous emission stored in the optical cavity has been observed. Also, preliminary results on the operation of an optical klystron are reported and interpreted

  5. ALOHA Cabled Observatory (ACO): Acoustic Doppler Current Profiler (ADCP): Temperature

    National Oceanic and Atmospheric Administration, Department of Commerce — The University of Hawaii's ALOHA ("A Long-term Oligotrophic Habitat Assessment") Cabled Observatory (ACO) is located 100 km north of the island of Oahu, Hawaii (22...

  6. ALOHA Cabled Observatory (ACO): Acoustic Doppler Current Profiler (ADCP): Velocity

    National Oceanic and Atmospheric Administration, Department of Commerce — The University of Hawaii's ALOHA ("A Long-term Oligotrophic Habitat Assessment") Cabled Observatory (ACO) is located 100 km north of the island of Oahu, Hawaii (22...

  7. ACO-AFSA Algorithm in Function Optimization and Its Application

    Wang Shi Gang

    2016-01-01

    Full Text Available ACO and AFSA as two kinds of new intelligent bionic algorithm, has better robustness, and the design method is simple and easy to understand. At present, in many engineering fields, they have been a pivotal position, but there are some defects in solving function optimization problems. Because of the lack of pheromone in the initial stage of ACO, the speed of the solution is relatively slow, and AFSA has the advantages of strong global convergence ability and fast speed. In this paper, based on the advantages and disadvantages of ACO and AFSA, two kinds of algorithms are integrated, and the advantage is enhanced, a better optimization algorithm is put forward: ACO-AFSA. The initial solution and improved state transition probabilities are obtained by AFSA, and the basic ACO is improved, the congestion degree of AFSA is introduced in the algorithm, makes most of ants’ initial optimization will not be randomly selected at a strong crowding restrictions. Experimental results show that the new algorithm can get the optimal solution with less number of iterations, which greatly saves computation time, and has higher accuracy and better convergence performance. Engineering, computing the shortest distance between the surface and plane of the problem has also been good results, the experimental results are satisfactory.

  8. Improving Network Performance using ACO Based Redundant Link Avoidance Algorithm

    B. Chandra Mohan

    2010-05-01

    Full Text Available In the wide spread internet, response time and pocket loss are inappropriate due to network traffic, as a result the network efficiency becomes worst and the system provides poor Quality of Service (QoS. An optimal routing protocol, especially multipath may avoid such traffic in the network. But existing routing protocols, both single path and multi path, concentrates only on finding the routes based on any one or some set of metrics, that not always suitable for dynamic, cloud natured network environment. Ant Colony Optimization (ACO based multipath routing protocol was suggested as an alternate to this problem by many researchers. The multipath ACO also provides same set of link(s for the source to destination, so that traffic merging again becomes a critical problem. This paper proposes an optimal solution to avoid the problem of traffic merging in the network by removing redundant link in the route. The Proposed algorithm, called 'Redundant Link Avoidance (RLA algorithm', is an ACO based multi path routing methodology, avoiding copious link in the suggested routes of ACO multipath protocol.

  9. An ACO approach for the Parallel Machines Scheduling Problem

    Gatica, Claudia R.; Esquivel, Susana Cecilia; Leguizamón, Guillermo

    2008-01-01

    The parallel machines scheduling problem (Pm) comprises the allocation of jobs on the system’s resources, i.e., a group of machines in parallel. The basic model consists of m identical machines and n jobs. The jobs are assigned according to resource availability following some allocation rule. In this work, we apply the Ant Colony Optimization (ACO) metaheuristic which includes in the construction solution process different specific heuristic to solve Pm for the minimization Maximum Tardiness...

  10. ACO in e-Learning: Towards an adaptive learning path

    Pushpa. M

    2012-03-01

    Full Text Available Today we are in an era where drastic advancements in networking and information technology are in action. The learning process has also taken these advancements, as a result of which e-learning came to thescene. Personalization in e-learning will improve the performance of the system. Recent researches are concentrating on providing adaptability to the learning management systems, depending upon the varying user needs and contexts. Adaptability can be provided at different levels .Providing an adaptive learning path according to the context of the learners’ is an important issue. An optimal adaptive learning path will help the learners in reducing the cognitive overload and disorientation, and thereby improving the efficiency of the Learning Management System (LMS. Ant Colony Optimization (ACO is a widely accepted technique since it provides an adaptive learning path to the learners. Meta-heuristic which is used in intelligent tutoring systems provides the learning path in an adaptive way. The most interesting feature of ACO is its adaptation and robustness in an environment where the learning materials and learners are changing frequently. In this paper we can have a look through the existing ACO approaches towards providing an adaptive learning path and an introduction towards an enhanced attribute ant for making the e-learning system more adaptive.

  11. ACO a Metaheuristic Technique for solving Network Problems and a Precise of Network Models

    Manila Pahwa

    2013-09-01

    Full Text Available With the growing importance of telecommunication and internet, more complex networked systems are being designed and developed. The challenges of dealing with vast complexity of networking problems such as load balancing, routing and network congestion accentuate the need of more sophisticated technique to solve these problems. Ant colony optimisation (ACO is one of the best and efficient solutions to cope up with these problems. This paper presents the following:- Theoretical study of Metaheuristic technique commonly named as Ant Colony Optimisation (ACO and how it is better than conventional algorithms, An Overview of ACO models and the reason behind being ACO better than other Conventional algorithms?

  12. Dolor mandibular de origen cardíaco

    MR Sáez Yuguero; A Bermejo Fenoll; JL Calvo Guirado; E. Álvarez Martínez

    2003-01-01

    En las complejas estructuras anatómicas orofaciales, asientan muchos procesos dolorosos. Las algias orofaciales más comunes tienen su origen a nivel dental, periodontal o en estructuras musculoesqueleticas. Sin embargo, el paciente puede manifestar dolor en esta región, bien en dientes o estructuras musculoesqueleticas, y la fuente originaria localizarse a distancia. A este tipo de dolor se le llama dolor heterotópico. Una posible fuente de dolor heterotópico es el dolor de origen cardíaco. E...

  13. MODELO ACO PARA LA RECOLECCIÓN DE RESIDUOS POR CONTENEDORES ACO MODEL APPLIED TO THE WASTE COLLECTION BY CONTAINERS

    Eduardo Salazar Hornig

    2009-08-01

    Full Text Available ACO es una metaheurística inspirada en el comportamiento de las colonias de hormigas para solucionar problemas de optimización combinatoria, por medio de la utilización de agentes computacionales simples que trabajan de manera cooperativa y se comunican mediante rastros de feromona artificiales. En este trabajo se presenta un modelo para resolver el Problema de Recolección de Residuos Domiciliarios por Contenedores, el que aplica un concepto de secuencias parciales de recolección que deben ser unidas para minimizar la distancia total de recolección. El problema de unir las secuencias parciales se representa como un TSP, el que es resuelto mediante un algoritmo ACO. En base a recomendaciones de la literatura, se calibran experimentalmente los parámetros del algoritmo y se recomiendan rangos de valores que representan buenos rendimientos promedio. El modelo se aplica a un sector de recolección de la comuna de San Pedro de la Paz, Chile, obteniéndose rutas de recolección que reducen la distancia total recorrida respecto de la actual ruta utilizada y de la solución obtenida con otro modelo desarrollado previamente.ACO is a metaheuristic inspired in the behavior of natural ant colonies to solve combinatorial optimization problems, based on simple agents that work cooperatively communicating by artificial pheromone trails. In this paper a model to solve the municipal waste collection problem by containers is presented, which applies a concept of partial collection sequences that must be joined to minimize the total collection distance. The problem to join the partial collection sequences is represented as a TSP, which is solved by an ACO algorithm. Based on the literature, algorithm parameters are experimentally calibrated and range of variations that represents good average solutions are recommended. The model is applied to a waste collection sector of the San Pedro de la Paz commune in Chile, obtaining recollection routes with less total

  14. Physicians' Participation In ACOs Is Lower In Places With Vulnerable Populations Than In More Affluent Communities.

    Yasaitis, Laura C; Pajerowski, William; Polsky, Daniel; Werner, Rachel M

    2016-08-01

    Early evidence suggested that accountable care organizations (ACOs) could improve health care quality while constraining costs, and ACOs are expanding throughout the United States. However, if disadvantaged patients have unequal access to physicians who participate in ACOs, that expansion may exacerbate health care disparities. We examined the relationship between physicians' participation in both Medicare and commercial ACOs across the country and the sociodemographic characteristics of their likely patient populations. Physicians' participation in ACOs varied widely across hospital referral regions, from nearly 0 percent to over 85 percent. After we adjusted for individual physician and practice characteristics, we found that physicians who practiced in ZIP Code Tabulation Areas where a higher percentage of the population was black, living in poverty, uninsured, or disabled or had less than a high school education-compared to other areas-had significantly lower rates of ACO participation than other physicians. Our findings suggest that vulnerable populations' access to physicians participating in ACOs may not be as great as access for other groups, which could exacerbate existing disparities in health care quality. PMID:27503961

  15. Hospitals Participating In ACOs Tend To Be Large And Urban, Allowing Access To Capital And Data.

    Colla, Carrie H; Lewis, Valerie A; Tierney, Emily; Muhlestein, David B

    2016-03-01

    Relationships between physicians and hospitals have changed considerably over the past decade, as hospitals and physician groups have integrated and new public and private payment policies have created financial interdependence. The extent to which accountable care organizations (ACOs) involve hospitals in their operations may prove to be vitally important, because managing hospital care is a key part of improving health care quality and lowering cost growth. Using primary data on ACO composition and capabilities paired with hospital characteristics, we found that 20 percent of US hospitals were part of an ACO in 2014. Hospitals that were in urban areas, were nonprofit, or had a smaller share of Medicare patients were more likely to participate in ACOs, compared to hospitals that were in more rural areas, were for-profit or government owned, or had a larger share of Medicare patients, respectively. Qualitative data identified the following advantages of including a hospital in an ACO: the availability of start-up capital, advanced data sharing, and engagement of providers across the care continuum. Although the 63 percent of ACOs that included hospitals offered more comprehensive services compared to ACOs without hospitals, we found no differences between the two groups in their ability to manage hospital-related aspects of patient care. PMID:26953297

  16. MOEA/D-ACO: a multiobjective evolutionary algorithm using decomposition and AntColony.

    Ke, Liangjun; Zhang, Qingfu; Battiti, Roberto

    2013-12-01

    Combining ant colony optimization (ACO) and the multiobjective evolutionary algorithm (EA) based on decomposition (MOEA/D), this paper proposes a multiobjective EA, i.e., MOEA/D-ACO. Following other MOEA/D-like algorithms, MOEA/D-ACO decomposes a multiobjective optimization problem into a number of single-objective optimization problems. Each ant (i.e., agent) is responsible for solving one subproblem. All the ants are divided into a few groups, and each ant has several neighboring ants. An ant group maintains a pheromone matrix, and an individual ant has a heuristic information matrix. During the search, each ant also records the best solution found so far for its subproblem. To construct a new solution, an ant combines information from its group's pheromone matrix, its own heuristic information matrix, and its current solution. An ant checks the new solutions constructed by itself and its neighbors, and updates its current solution if it has found a better one in terms of its own objective. Extensive experiments have been conducted in this paper to study and compare MOEA/D-ACO with other algorithms on two sets of test problems. On the multiobjective 0-1 knapsack problem,MOEA/D-ACO outperforms the MOEA/D with conventional genetic operators and local search on all the nine test instances. We also demonstrate that the heuristic information matrices in MOEA/D-ACO are crucial to the good performance of MOEA/D-ACO for the knapsack problem. On the biobjective traveling salesman problem, MOEA/D-ACO performs much better than the BicriterionAnt on all the 12 test instances. We also evaluate the effects of grouping, neighborhood, and the location information of current solutions on the performance of MOEA/D-ACO. The work in this paper shows that reactive search optimization scheme, i.e., the "learning while optimizing" principle, is effective in improving multiobjective optimization algorithms. PMID:23757576

  17. Asthma-COPD Overlap Syndrome (ACOS): Single disease entity or not? Could exhaled nitric oxide be a useful biomarker for the differentiation of ACOS, asthma and COPD?

    Karampitsakos, Theodoros; Gourgoulianis, Konstantinos I

    2016-06-01

    Asthma and chronic obstructive pulmonary disease (COPD) represent two major public health problems. However, there is a significant proportion of patients with a mixed asthma-COPD phenotype. This condition is defined as asthma-COPD overlap syndrome (ACOS). Since there are no internationally accepted criteria for the diagnosis of that syndrome, its management remains difficult. Given the fact that patients with ACOS have an increased risk of exacerbation and hospitalization, there is a pressing need for a more targeted approach and better management. We propose that fractional exhaled nitric oxide (FeNO), a marker of eosinophilic inflammation, could help clinicians differentiate ACOS from asthma and COPD. We evaluate this hypothesis, using data derived from the existing literature. PMID:27142135

  18. The Impact Of Medicare ACOs On Improving Integration And Coordination Of Physical And Behavioral Health Care.

    Fullerton, Catherine A; Henke, Rachel M; Crable, Erica; Hohlbauch, Andriana; Cummings, Nicholas

    2016-07-01

    The accountable care organization (ACO) model holds the promise of reducing costs and improving the quality of care by realigning payment incentives to focus on health outcomes instead of service volume. One key to managing the total cost of care is improving care coordination for and treatment of people with behavioral health disorders. We examined qualitative data from ninety organizations participating in Medicare ACO demonstration programs from 2012 through 2015 to determine whether and how they focused on behavioral health care. These ACOs had mixed degrees of engagement in improving behavioral health care for their populations. The biggest challenges included a lack of behavioral health care providers, data availability, and sustainable financing models. Nonetheless, we found substantial interest in integrating behavioral health care into primary care across a majority of the ACOs. PMID:27385242

  19. Methodology to Optimize Manufacturing Time for a CNC Using a High Performance Implementation of ACO

    Oscar Montiel-Ross

    2012-10-01

    Full Text Available In this paper, an efficient methodology to generate optimal and/or quasi‐optimal sequences of G commands to minimize the manufacturing time is presented. Our solution starts from original G codes provided by application CAD/CAM software. Here, first we tackled the problem of reducing the time of the travel path for drilling of an industrial robotic manufacturing machine. The methodology can be easily implemented for free distribution or commercial CAD/CAM software without achieving any modification to it. Several experiments that demonstrate how this proposal can help to outperform solutions provided by application software are presented, consistent improvements around 62% were obtained. Moreover, for optimizing the time along the travel path, we present a high performance implementation of Ant Colonies (ACO known as Parallel ACO (P‐ACO that allows achieving the optimization task efficiently by speeding up the original ACO. A Graphical User Interface that integrates the whole process is shown.

  20. An ACO model for a non-stationary formulation of the single elevator problem

    Molina, Silvia; Leguizamón, Mario Guillermo; Alba Torres, Enrique

    2007-01-01

    The Ant Colony Optimization (ACO) metaheuristic is a bio-inspired approach for hard combinatorial optimization problems for stationary and non-stationary environments. In the ACO metaheuristic, a colony of artificial ants cooperate for finding high quality solutions in a reasonable time. An interesting example of a non-stationary combinatorial optimization problem is the Multiple Elevators Problem (MEP) which consists in finding a sequence of movements for each elevator to perform in a buildi...

  1. CACONET: Ant Colony Optimization (ACO) Based Clustering Algorithm for VANET

    Bajwa, Khalid Bashir; Khan, Salabat; Chaudary, Nadeem Majeed; Akram, Adeel

    2016-01-01

    A vehicular ad hoc network (VANET) is a wirelessly connected network of vehicular nodes. A number of techniques, such as message ferrying, data aggregation, and vehicular node clustering aim to improve communication efficiency in VANETs. Cluster heads (CHs), selected in the process of clustering, manage inter-cluster and intra-cluster communication. The lifetime of clusters and number of CHs determines the efficiency of network. In this paper a Clustering algorithm based on Ant Colony Optimization (ACO) for VANETs (CACONET) is proposed. CACONET forms optimized clusters for robust communication. CACONET is compared empirically with state-of-the-art baseline techniques like Multi-Objective Particle Swarm Optimization (MOPSO) and Comprehensive Learning Particle Swarm Optimization (CLPSO). Experiments varying the grid size of the network, the transmission range of nodes, and number of nodes in the network were performed to evaluate the comparative effectiveness of these algorithms. For optimized clustering, the parameters considered are the transmission range, direction and speed of the nodes. The results indicate that CACONET significantly outperforms MOPSO and CLPSO. PMID:27149517

  2. Dolor mandibular de origen cardíaco

    MR Sáez Yuguero

    2003-10-01

    Full Text Available En las complejas estructuras anatómicas orofaciales, asientan muchos procesos dolorosos. Las algias orofaciales más comunes tienen su origen a nivel dental, periodontal o en estructuras musculoesqueleticas. Sin embargo, el paciente puede manifestar dolor en esta región, bien en dientes o estructuras musculoesqueleticas, y la fuente originaria localizarse a distancia. A este tipo de dolor se le llama dolor heterotópico. Una posible fuente de dolor heterotópico es el dolor de origen cardíaco. Este articulo presenta un caso clínico en el que el dolor mandibular bilateral fue el síntoma inicial de una cardiopatía isquémica que fue erróneamente etiquetada de artrosis de la articulación temporomandibular.In the complex orofacial anatomic structures, many painful processes are felt. The most common orofacial pains have their origin at dental or periodontal level, or in muscle -skeletical structures. However, the patient can have pain in this area- either in teeth or muscle-eskeletical structures- and the originating source can be located at a distance. This type of pain is called heterotopic pain. A possible source of heterotopic pain is the pain of cardiac origin. This paper presents a clinical case in which the bilateral mandibular pain is the initial symptom of an ischemic cardiopathy that was erroneously labeled as temporomandibular arthrosis.

  3. CACONET: Ant Colony Optimization (ACO) Based Clustering Algorithm for VANET.

    Aadil, Farhan; Bajwa, Khalid Bashir; Khan, Salabat; Chaudary, Nadeem Majeed; Akram, Adeel

    2016-01-01

    A vehicular ad hoc network (VANET) is a wirelessly connected network of vehicular nodes. A number of techniques, such as message ferrying, data aggregation, and vehicular node clustering aim to improve communication efficiency in VANETs. Cluster heads (CHs), selected in the process of clustering, manage inter-cluster and intra-cluster communication. The lifetime of clusters and number of CHs determines the efficiency of network. In this paper a Clustering algorithm based on Ant Colony Optimization (ACO) for VANETs (CACONET) is proposed. CACONET forms optimized clusters for robust communication. CACONET is compared empirically with state-of-the-art baseline techniques like Multi-Objective Particle Swarm Optimization (MOPSO) and Comprehensive Learning Particle Swarm Optimization (CLPSO). Experiments varying the grid size of the network, the transmission range of nodes, and number of nodes in the network were performed to evaluate the comparative effectiveness of these algorithms. For optimized clustering, the parameters considered are the transmission range, direction and speed of the nodes. The results indicate that CACONET significantly outperforms MOPSO and CLPSO. PMID:27149517

  4. RNA Interference of 1-Aminocyclopropane-1-carboxylic Acid Oxidase (ACO1 and ACO2 Genes Expression Prolongs the Shelf Life of Eksotika (Carica papaya L. Papaya Fruit

    Rogayah Sekeli

    2014-06-01

    Full Text Available The purpose of this study was to evaluate the effectiveness of using RNA interference in down regulating the expression of 1-aminocyclopropane-1-carboxylic acid oxidase gene in Eksotika papaya. One-month old embryogenic calli were separately transformed with Agrobacterium strain LBA 4404 harbouring the three different RNAi pOpOff2 constructs bearing the 1-aminocyclopropane-1-carboxylic acid oxidase gene. A total of 176 putative transformed lines were produced from 15,000 calli transformed, selected, then regenerated on medium supplemented with kanamycin. Integration and expression of the targeted gene in putatively transformed lines were verified by PCR and real-time RT-PCR. Confined field evaluation of a total of 31 putative transgenic lines planted showed a knockdown expression of the targeted ACO1 and ACO2 genes in 13 lines, which required more than 8 days to achieve the full yellow colour (Index 6. Fruits harvested from lines pRNAiACO2 L2-9 and pRNAiACO1 L2 exhibited about 20 and 14 days extended post-harvest shelf life to reach Index 6, respectively. The total soluble solids contents of the fruits ranged from 11 to 14° Brix, a range similar to fruits from non-transformed, wild type seed-derived plants.

  5. MGA trajectory planning with an ACO-inspired algorithm

    Ceriotti, Matteo; Vasile, Massimiliano

    2010-11-01

    Given a set of celestial bodies, the problem of finding an optimal sequence of swing-bys, deep space manoeuvres (DSM) and transfer arcs connecting the elements of the set is combinatorial in nature. The number of possible paths grows exponentially with the number of celestial bodies. Therefore, the design of an optimal multiple gravity assist (MGA) trajectory is a NP-hard mixed combinatorial-continuous problem. Its automated solution would greatly improve the design of future space missions, allowing the assessment of a large number of alternative mission options in a short time. This work proposes to formulate the complete automated design of a multiple gravity assist trajectory as an autonomous planning and scheduling problem. The resulting scheduled plan will provide the optimal planetary sequence and a good estimation of the set of associated optimal trajectories. The trajectory model consists of a sequence of celestial bodies connected by two-dimensional transfer arcs containing one DSM. For each transfer arc, the position of the planet and the spacecraft, at the time of arrival, are matched by varying the pericentre of the preceding swing-by, or the magnitude of the launch excess velocity, for the first arc. For each departure date, this model generates a full tree of possible transfers from the departure to the destination planet. Each leaf of the tree represents a planetary encounter and a possible way to reach that planet. An algorithm inspired by ant colony optimization (ACO) is devised to explore the space of possible plans. The ants explore the tree from departure to destination adding one node at the time: every time an ant is at a node, a probability function is used to select a feasible direction. This approach to automatic trajectory planning is applied to the design of optimal transfers to Saturn and among the Galilean moons of Jupiter. Solutions are compared to those found through more traditional genetic-algorithm techniques.

  6. Relative Study of CGS with ACO and BCO Swarm Intelligence Techniques

    T.Hashni

    2012-09-01

    Full Text Available Swarm intelligence is the collective-level, problem-solving behavior of groups of relatively simple agents.Local interactions among agents, either direct or indirect through the environment, are fundamental for theemergence of swarm intelligence. Ant Colony Optimization (ACO is a swarm based meta-heuristic method that isinspired by the behavior of real ant colonies. Bee Colony Optimization (BCO meta-heuristic belongs to the groupof Swarm Intelligence techniques. Consultant Guided Search (CGS is a new hybrid meta heuristic, which combinesnew ideas with concepts found in Ant colony Optimization (ACO, Bee Colony Optimization (BCO technique. Thispaper presents comparative study of CGS, ACO, BCO techniques and the flexibility of CGS.

  7. An improved adaptive ACO meta heuristic for scheduling multimedia traffic across the 802.11e EDCA

    Ditze, Michael; Becker, Markus

    2008-01-01

    This paper presents an adaptive near-optimal scheduler for multimedia traffic for the 802.11e Enhanced Distributed Channel Access (EDCA) medium access control scheme. The scheduler exploits the ant colony optimization (ACO) meta heuristic to tackle the challenge of packet scheduling. ACO is a biologically inspired algorithm that is known to find near-optimal solutions for combinatorial optimization problems. Thus, we expect that ACO scheduling produces more efficient schedules than comparable deterministic scheduling approaches at the expenses of a computational overhead it introduces. We compare ACO scheduling relevant deterministic scheduling approaches, and in particular the MLLF scheduler that is specifically designed for the needs of compressed multimedia applications. The purpose of the evaluation is twofold. It allows to draw conclusions on the feasibility of ACO scheduling for multimedia traffic while it serves as a benchmark to determine to what extent deterministic schedulers fall short of a near-optimal solution.

  8. Postharvest Analysis of Lowland Transgenic Tomato Fruits Harboring hpRNAi-ACO1 Construct

    Bita Behboodian

    2012-01-01

    Full Text Available The plant hormone, ethylene, is an important regulator which involved in regulating fruit ripening and flower senescence. In this study, RNA interference (RNAi technology was employed to silence the genes involved in ethylene biosynthetic pathway. This was achieved by blocking the expression of specific gene encoding the ACC oxidase. Initially, cDNA corresponding to ACO1 of lowland tomato cultivar (MT1, which has high identity with ACO1 of Solanum lycopersicum in GenBank, was cloned through RT-PCR. Using a partial coding region of ACO1, one hpRNAi transformation vector was constructed and expressed ectopically under the 35S promoter. Results showed that transgenic lines harboring the hpRNA-ACO1 construct had lower ethylene production and a longer shelf life of 32 days as compared to 10 days for wild-type fruits. Changes in cell wall degrading enzyme activities were also investigated in cases where the transgenic fruits exhibited reduced rates of firmness loss, which can be associated with a decrease in pectin methylesterase (PME and polygalacturonase (PG activities. However, no significant change was detected in both transgenic and wild-type fruits in terms of β-galactosidase (β-Gal activity and levels of total soluble solid, titratable acid and ascorbic acid.

  9. ACO Based Feature Subset Selection for Multiple k-Nearest Neighbor Classifiers

    Shailendra Kumar Shrivastava

    2011-05-01

    Full Text Available The k-nearest neighbor (k-NN is one of the most popular algorithms used for classification in various fields of pattern recognition & data mining problems. In k-nearest neighbor classification, theresult of a new instance query is classified based on the majority of k-nearest neighbors. Recently researchers have begun paying attention to combining a set of individual k-NN classifiers, each using adifferent subset of features, with the hope of improving the overall classification accuracy. In this paper we proposed Ant Colony Optimization (ACO based feature subset selection for multiple k-nearest neighbor classifiers. The ACO is an iterative meta-heuristic search technique, which inspired by the foraging food behavior of real ant colonies. In ACO, real ants become artificial ants with the particular abilities such as distance determination & tour memory. The solution is constructed in a probabilistic waybased on pheromone model in the form of numerical values. The concept of this approach is selecting the best possible subsets of feature from the original set with the help of ACO and combines the outputs from multiple k-NN classifiers. The experimental results show that this proposed method improves the average classification accuracy of k-NN classifier.

  10. New data association technique based on ACO with directional information considered

    2008-01-01

    Due to the advantages of ant colony optimization (ACO) in solving complex problems, a new data association algorithm based on ACO in a cluttered environment called DACDA is proposed. In the proposed method, the concept for tour and the length of tour are redefined. Additionally, the directional information is incorporated into the proposed method because it is one of the most important factors that affects the performance of data association. Kalraan filter is employed to estimate target states. Computer simulation results show that the proposed method could carry out data association in an acceptable CPU time, and the correct data association rate is higher than that obtained by the data association (DA) algorithm not combined with directional information.

  11. A Novel Framework Based on ACO and PSO for RNA Secondary Structure Prediction

    Gang Wang

    2013-01-01

    Full Text Available Prediction of RNA structure is a useful process for creating new drugs and understanding genetic diseases. In this paper, we proposed a particle swarm optimization (PSO and ant colony optimization (ACO based framework (PAF for RNA secondary structure prediction. PAF consists of crucial stem searching (CSS and global sequence building (GSB. In CSS, a modified ACO (MACO is used to search the crucial stems, and then a set of stems are generated. In GSB, we used a modified PSO (MPSO to construct all the stems in one sequence. We evaluated the performance of PAF on ten sequences, which have length from 122 to 1494. We also compared the performance of PAF with the results obtained from six existing well-known methods, SARNA-Predict, RnaPredict, ACRNA, PSOfold, IPSO, and mfold. The comparison results show that PAF could not only predict structures with higher accuracy rate but also find crucial stems.

  12. Experimental evaluation of a R134a/CO2 cascade refrigeration plant

    Sanz Kock, Carlos; Llopis Doménech, Rodrigo; Sánchez García-Vacas, Daniel; Cabello López, Ramón; Torrella Alcaraz, Enrique

    2014-01-01

    We present the experimental evaluation of a R134a/CO2 cascade refrigeration plant designed for low evaporation temperature in commercial refrigeration applications. The test bench incorporates two single- stage vapour compression cycles driven by semi hermetic compressors coupled thermally through two brazed plate cascade heat exchangers working in parallel and controlled by electronic expansion valves. The experimental evaluation (45 steady-states) covers evaporating temperatures from -40 to...

  13. Relative Study of CGS with ACO and BCO Swarm Intelligence Techniques

    T.Hashni; T Amudha

    2012-01-01

    Swarm intelligence is the collective-level, problem-solving behavior of groups of relatively simple agents.Local interactions among agents, either direct or indirect through the environment, are fundamental for theemergence of swarm intelligence. Ant Colony Optimization (ACO) is a swarm based meta-heuristic method that isinspired by the behavior of real ant colonies. Bee Colony Optimization (BCO) meta-heuristic belongs to the groupof Swarm Intelligence techniques. Consultant Guided Search (CG...

  14. Ant Colony Optimization ACO For The Traveling Salesman Problem TSP Using Partitioning

    Alok Bajpai; Raghav Yadav

    2015-01-01

    Abstract An ant colony optimization is a technique which was introduced in 1990s and which can be applied to a variety of discrete combinatorial optimization problem and to continuous optimization. The ACO algorithm is simulated with the foraging behavior of the real ants to find the incremental solution constructions and to realize a pheromone laying-and-following mechanism. This pheromone is the indirect communication among the ants. In this paper we introduces the partitioning technique ba...

  15. Tailoring Systems Engineering Processes in a Conceptual Design Environment: A Case Study at NASA Marshall Spaceflight Center's ACO

    Mulqueen, John; Maples, C. Dauphne; Fabisinski, Leo, III

    2012-01-01

    This paper provides an overview of Systems Engineering as it is applied in a conceptual design space systems department at the National Aeronautics and Space Administration (NASA) Marshall Spaceflight Center (MSFC) Advanced Concepts Office (ACO). Engineering work performed in the NASA MFSC's ACO is targeted toward the Exploratory Research and Concepts Development life cycle stages, as defined in the International Council on Systems Engineering (INCOSE) System Engineering Handbook. This paper addresses three ACO Systems Engineering tools that correspond to three INCOSE Technical Processes: Stakeholder Requirements Definition, Requirements Analysis, and Integration, as well as one Project Process Risk Management. These processes are used to facilitate, streamline, and manage systems engineering processes tailored for the earliest two life cycle stages, which is the environment in which ACO engineers work. The role of systems engineers and systems engineering as performed in ACO is explored in this paper. The need for tailoring Systems Engineering processes, tools, and products in the ever-changing engineering services ACO provides to its customers is addressed.

  16. De la Locura de doble forma a la Psicosis maníaco-depresiva.

    - Consejo de Redacción

    1995-01-01

    Full Text Available Sin entrar en polémicas sobre a quién atribuir la primera descripción de lo que actualmente llamamos Psicosis maníaco-depresiva, es decir, sin tomar partido por Baillarger o J.-P. Falret, lo cierto es que a mediados del pasado siglo los alienistas franceses orquestaron un saber nosológico en el que se reunían en una única categoría dos manifestaciones extremas del humor: la manía y la melancolía. Tras las descripciones fundacionales de Baillarger y de Falret, fechadas ambas en el mismo año, 1854, se abrió un espacio nosológico opuesto al terreno de los delirios crónicos: las psicosis del humor frente a las psicosis de la razón, o bien psicosis maníaco-depresiva frente a esquizofrenia-paranoia. De la última cosecha del nosógrafo por excelencia, Emil Kraepelin, proviene la descripción clínica más completa y matizada de la locura maníaco-depresiva (das manisch-depressive Irresein. Dos años después, en 1915, S. Freud mostró en Duelo y Melancolía la infraestructura metapsicológica de la manía y de la melancolía.

  17. Predicting coal ash fusion temperature based on its chemical composition using ACO-BP neural network

    Coal ash fusion temperature is important to boiler designers and operators of power plants. Fusion temperature is determined by the chemical composition of coal ash, however, their relationships are not precisely known. A novel neural network, ACO-BP neural network, is used to model coal ash fusion temperature based on its chemical composition. Ant colony optimization (ACO) is an ecological system algorithm, which draws its inspiration from the foraging behavior of real ants. A three-layer network is designed with 10 hidden nodes. The oxide contents consist of the inputs of the network and the fusion temperature is the output. Data on 80 typical Chinese coal ash samples were used for training and testing. Results show that ACO-BP neural network can obtain better performance compared with empirical formulas and BP neural network. The well-trained neural network can be used as a useful tool to predict coal ash fusion temperature according to the oxide contents of the coal ash

  18. Solving optimum operation of single pump unit problem with ant colony optimization (ACO) algorithm

    For pumping stations, the effective scheduling of daily pump operations from solutions to the optimum design operation problem is one of the greatest potential areas for energy cost-savings, there are some difficulties in solving this problem with traditional optimization methods due to the multimodality of the solution region. In this case, an ACO model for optimum operation of pumping unit is proposed and the solution method by ants searching is presented by rationally setting the object function and constrained conditions. A weighted directed graph was constructed and feasible solutions may be found by iteratively searching of artificial ants, and then the optimal solution can be obtained by applying the rule of state transition and the pheromone updating. An example calculation was conducted and the minimum cost was found as 4.9979. The result of ant colony algorithm was compared with the result from dynamic programming or evolutionary solving method in commercial software under the same discrete condition. The result of ACO is better and the computing time is shorter which indicates that ACO algorithm can provide a high application value to the field of optimal operation of pumping stations and related fields.

  19. Enfermedad inflamatoria intestinal en pacientes celíacos Inflammatory bowel disease in celiac patients

    M. Masachs

    2007-08-01

    Full Text Available Introducción: se ha sugerido una potencial asociación entre la enfermedad celíaca y la enfermedad inflamatoria intestinal, que puede justificar que ambas enfermedades puedan presentarse en un mismo enfermo o en sus familiares de primer orden con mayor frecuencia de lo esperado. Objetivo: determinar la prevalencia de la enfermedad de Crohn y la colitis ulcerosa en los enfermos celíacos y en sus familiares. Método: estudio epidemiológico prospectivo transversal en un grupo de pacientes celíacos, sus familiares de primer grado y un grupo control de características epidemiológicas similares, constituido por familiares de pacientes que acuden al Servicio de Urgencias por un problema agudo. Para detectar la existencia de colitis ulcerosa y enfermedad de Crohn en los celíacos y sus familiares, se realizó una entrevista semiestructurada. Resultados: se han incluido 86 celíacos y 432 familiares, que se han comparado con 809 controles (129 pacientes con una enfermedad aguda y 680 familiares de primer grado suyos. Se han detectado 3 casos de enfermedad de Crohn en el grupo de los enfermos celíacos y 4 casos de enfermedad de Crohn en sus familiares. Sólo se ha detectado 1 caso de enfermedad de Crohn en el grupo control (p Introduction: a potential association between celic disease and inflammatory bowel disease hs been suggested, which may explain the fact that both disorders occasionally present in one patient or in his/her first-degree relatives more frequently than expected. Objective: to establish the prevalence of Crohn's disease and ulcerative colitis in celiac patients and their relatives. Method: a cross-sectional, prospective epidemiological study in a group of celiac patients, their first-degree relatives, and a control group with similar epidemiological characteristics including the relatives of patients presenting at the ER for acute conditions. A semistructured interview was used to identify the presence of Crohn's disease and

  20. Taponamiento cardíaco por hipotiroidismo: descripción de 2 casos

    José Rafael Rojas-Solano

    2005-07-01

    Full Text Available Rara vez el derrame pericárdico en el hipotiroidismo evoluciona al taponamiento cardíaco, complicación que es mortal si no se diagnostica y trata a tiempo. En este artículo describimos dos singulares casos y discutimos aspectos importantes de la fisiopatología, diagnóstico y manejo de esta enfermedad.Pericardial effusion in hypothyroidism seldom evolves to cardiac tamponade, a fatal complication if diagnosis and treatment are delayed. In this article, we describe 2 singular cases and discuss important facts about the pathophysiology, diagnosis and management of this disease.

  1. Actualización en legislación de alimentos para celíacos

    Pellicer, K.; Huber, Bárbara; Benítez, F.; Bigeon, G.; Barbero, R.; Salum, L.; Copes, Julio

    2014-01-01

    Se realizó un análisis de la normativa sanitaria sobre alimentos para celíacos y su impacto en la población celíaca, mediante la investigación y comparación de las normativas sanitarias argentina e internacional sobre alimentos libres de gluten y el análisis de las consultas realizadas al listado oficial argentino de productos libres de gluten. La norma CODEX STAN 118/1979 y la normativa de la Comunidad Europea reconocen como alimentos “exentos de gluten” a los que contienen hasta 20 mg/kg y ...

  2. Blastocystis hominis en pacientes celíacos sintomáticos

    Oscar Manuel Villa Jiménez; Ángel Escobedo Carbonell; Olga Marina Hano García; Lisette Wood Rodríguez; Frank Pérez Triana; Licet González Fabián

    2012-01-01

    Introducción. La enfermedad celíaca (EC) no diagnosticada o no tratada compromete histológica, inmunológica y nutricionalmente a quienes la sufren. Estas alteraciones permitirían la infección por parásitos que no causarían síntomas en pacientes inmunocompetentes, como por ejemplo el Blastocystis hominis (Bh). Objetivo. Analizar la presencia de Bh en celíacos sintomáticos y describir el cuadro clínico, estado histológico, inmunológico y nutricional en dichos pacientes. Material y métodos. E...

  3. Domainwise Web Page Optimization Based On Clustered Query Sessions Using Hybrid Of Trust And ACO For Effective Information Retrieval

    Dr. Suruchi Chawla

    2015-08-01

    Full Text Available Abstract In this paper hybrid of Ant Colony OptimizationACO and trust has been used for domainwise web page optimization in clustered query sessions for effective Information retrieval. The trust of the web page identifies its degree of relevance in satisfying specific information need of the user. The trusted web pages when optimized using pheromone updates in ACO will identify the trusted colonies of web pages which will be relevant to users information need in a given domain. Hence in this paper the hybrid of Trust and ACO has been used on clustered query sessions for identifying more and more relevant number of documents in a given domain in order to better satisfy the information need of the user. Experiment was conducted on the data set of web query sessions to test the effectiveness of the proposed approach in selected three domains Academics Entertainment and Sports and the results confirm the improvement in the precision of search results.

  4. Studies on Pumice Lightweight Aggregate Concrete with Quarry Dust Using Mathematical Modeling Aid of ACO Techniques

    J. Rex

    2016-01-01

    Full Text Available The lightweight aggregate is an aggregate that weighs less than the usual rock aggregate and the quarry dust is a rock particle used in the concrete for the experimentation. The significant intention of the proposed technique is to frame a mathematical modeling with the aid of the optimization techniques. The mathematical modeling is done by minimizing the cost and time consumed in the case of extension of the real time experiment. The proposed mathematical modeling is utilized to predict four output parameters such as compressive strength (Mpa, split tensile strength (Mpa, flexural strength (Mpa, and deflection (in mm. Here, the modeling is carried out with three different optimization techniques like genetic algorithm (GA, particle swarm optimization (PSO, and ant colony optimization (ACO with 80% of data from experiment utilized for the training and the remaining 20% for the validation. Finally, while testing, the error value is minimized and the performance obtained in the ACO for the parameters such as compressive strength, split tensile strength, flexural strength, and deflection is 91%, 98%, 87%, and 94% of predicted values, respectively, in the mathematical modeling.

  5. Marcadores cardíacos na medicina veterinária Cardiac markers in veterinary medicine

    Letícia Andreza Yonezawa

    2010-02-01

    Full Text Available Os marcadores cardíacos são utilizados com o intuito de auxiliar no diagnóstico clínico de animais com doença cardíaca com maior acurácia e em menor tempo possível, possibilitando o estabelecimento do prognóstico e a terapia precocemente. Entretanto, em medicina veterinária, no Brasil, sua aplicabilidade ainda é, em geral, restrita a pesquisas. Esta revisão tem como objetivo abordar os principais marcadores cardíacos para que futuramente estes possam se tornar índices essenciais na avaliação cardíaca.Cardiac markers have been used in order to assist clinical diagnosis of animals with heart disease, more accurately, enabling the establishment of earlier prognosis and therapy. However, in Brazilian veterinary medicine, these markers are generally still restricted to researches. This review aims to approach the major cardiac markers, which further may become essential indexes in heart assessment.

  6. Application of GA, PSO, and ACO Algorithms to Path Planning of Autonomous Underwater Vehicles

    Mohammad Pourmahmood Aghababa; Mohammad Hossein Amrollahi; Mehdi Borjkhani

    2012-01-01

    In this paper,an underwater vehicle was modeled with six dimensional nonlinear equations of motion,controlled by DC motors in all degrees of freedom.Near-optimal trajectories in an energetic environment for underwater vehicles were computed using a numerical solution of a nonlinear optimal control problem (NOCP).An energy performance index as a cost function,which should be minimized,was defined.The resulting problem was a two-point boundary value problem (TPBVP).A genetic algorithm (GA),particle swarm optimization (PSO),and ant colony optimization (ACO) algorithms were applied to solve the resulting TPBVP.Applying an Euler-Lagrange equation to the NOCE a conjugate gradient penalty method was also adopted to solve the TPBVP.The problem of energetic environments,involving some energy sources,was discussed.Some near-optimal paths were found using a GA,PSO,and ACO algorithms.Finally,the problem of collision avoidance in an energetic environment was also taken into account.

  7. Optimization of Vibration Reduction Ability of Ladder Tracks by FEM Coupled with ACO

    Hao Jin

    2015-01-01

    Full Text Available Ladder track, which has drawn increased attention in scientific communities, is an effective method for reducing vibrations from underground railways. In order to optimize the vibration reduction ability of ladder track, a new method, that is, the finite element method (FEM coupled with ant colony optimization (ACO, has been proposed in this paper. We describe how to build the FEM model verified by the vibration tests in the Track Vibration Abatement and Control Laboratory and how to couple the FEM with ACO. The density and elasticity modulus of the sleeper pad are optimized using this method. After optimization, the vibration acceleration level of the supporting platform in the 1–200 Hz range was reduced from 102.8 dB to 94.4 dB. The optimized density of the sleeper pad is 620 kg/m3, and the optimized elasticity modulus of the sleeper pad is 6.25 × 106 N/m2.

  8. NHETS - Estudo de Necrópsias de Pacientes Submetidos a Transplante Cardíaco

    Thiago Ninck Valette

    2014-06-01

    Full Text Available Fundamento: Discordâncias entre diagnóstico pre e post-mortem são relatadas na literatura, podendo variar de 4,1 a 49,8% dentre os casos encaminhados para exame necroscópico, com importante repercussão no tratamento dos pacientes. Objetivo: Analisar pacientes com óbito após o transplante cardíaco e confrontar os diagnósticos pre e post-mortem. Métodos: Por meio da revisão de prontuários, foram analisados dados clínicos, presença de comorbidades, esquema de imunossupressão, exames laboratoriais, causa clínica do óbito e causa do óbito à necrópsia. Foram confrontadas, então, a causa clínica e a causa necroscópica do óbito de cada paciente. Resultados: Foram analisados 48 óbitos submetidos à necrópsia no período de 2000 a 2010; 29 (60,4% tiveram diagnósticos clínico e necroscópico concordantes, 16 (33,3% tiveram diagnósticos discordantes e três (6,3% tiveram diagnóstico não esclarecido. Entre os discordantes, 15 (31,3% apresentaram possível impacto na sobrevida e um (2,1% não apresentou impacto na sobrevida. O principal diagnóstico clínico feito equivocadamente foi o de infecção, com cinco casos (26,7% dos discordantes, seguido por rejeição hiperaguda, com quatro casos (20% dos discordantes, e tromboembolismo pulmonar, com três casos (13,3% dos discordantes. Conclusão: Discordâncias entre o diagnóstico clínico e achados da necrópsia são comumente encontradas no transplante cardíaco. Novas estratégias no aperfeiçoamento do diagnóstico clínico devem ser introduzidas, considerando-se os resultados da necrópsia para melhoria do tratamento da insuficiência cardíaca por meio do transplante cardíaco.

  9. Transplante cardíaco humano: experiência inicial Human cardiac transplant: initial experience

    Noedir A. G Stolf; Edimar Bocchi; Pedro C. P Lemos; Fábio Biscegli Jatene; Pablo M. A. Pomerantzeff; Lourdes Higushi; Jorge Kalil; Alfredo I. FIORELLI; José Otávio C Auler Júnior; Giovanni Bellotti; Lélio A Silva; Fúlvio Pileggi; Adib D Jatene

    1986-01-01

    No Instituto do Coração, de março de 1985 a fevereiro de 1986,11 pacientes foram submetidos a transplante cardíaco ortotópico. Eram todos do sexo masculino, com idade variando de 39 a 54 anos; 6 com cardiopatia isquémica, 4 com cardiomiopatia dilatada e um com cardiomiopatia chagásica. Foi realizado estudo hemodinâmico através de catéter de Swan-Ganz, no pré-operatório, no pós-operatório, após estabilização na unidade de recuperação, e trinta ou mais dias após o transplante. Os dados mostram ...

  10. As Camélias Oitocentistas do Buçaco

    Cordeiro, Liliana Margarida Correia

    2014-01-01

    Durante séculos, o género Camellia desempenhou um papel importante como ornamental. Em Portugal, o fascínio por estas plantas teve o seu clímax no século XIX, principalmente no noroeste e na cidade de Sintra, onde as condições são particularmente favoráveis para o seu cultivo. A Mata do Buçaco, uma floresta no centro do país, é das áreas menos conhecidas de camélias. As suas camélias datam deste período, quando estas plantas eram itens de colecção para os nobres. Alfredo Allen, Visconde da Qu...

  11. A new VUV high resolution undulator-based beamline at Super-ACO

    The VUV undulator-based high resolution SU5 beamline, designed to operate in the 5-45 eV photon energy range, is under construction at Super-ACO. It is composed of three toroidal mirrors around a 6.65 m Eagle off-plane normal incidence monochromator, whose induced-astigmatism is negligible owing to an horizontal focusing onto the gratings. With an optical design minimizing the aberrations and optimizing the throughput through the entrance slit, and with a careful choice of the optical coatings, the SU5 beamline should provide in the near future more than 1010 ph/s at the sample level for a 1/50000 bandwidth in the 5-25 eV energy range. The ultimate resolving power should be higher than 105. (orig.)

  12. Experimental evaluation of a R134a/CO2 cascade refrigeration plant

    We present the experimental evaluation of a R134a/CO2 cascade refrigeration plant designed for low evaporation temperature in commercial refrigeration applications. The test bench incorporates two single-stage vapour compression cycles driven by semi hermetic compressors coupled thermally through two brazed plate cascade heat exchangers working in parallel and controlled by electronic expansion valves. The experimental evaluation (45 steady-states) covers evaporating temperatures from −40 to −30 °C and condensing from 30 to 50 °C. In each steady-state, we conducted a sweep of the condensing temperature of the low temperature cycle with speed variation of the high temperature compressor. Here, the energy performance of the plant is analysed, focussing on the compressors' performance, temperature difference in the cascade heat exchanger, cooling capacity, COP and compressors discharge temperatures. - Highlights: • The experimental evaluation of a R134a/CO2 cascade refrigeration plant is presented. • Temperature difference in cascade heat exchanger varied from 3.3 to 5.3 °C. • Variation of intermediate level produced maximum COP variations of 6%. • Cooling capacity ranged from 4.5 kW (−40 and 40 °C) to 7.5 kW (−30 and 30 °C). • COP ranged from 1.05 (−40 and 40 °C) to 1.65 (−30 and 30 °C)

  13. Produção de amoníaco e sua optimização

    Roque, Marta de Jesus

    2008-01-01

    Com este trabalho pretendeu-se estudar o estado da arte de produção de amoníaco que é uma matéria-prima importante para a produção de fertilizantes nitrogenados e é usado frequentemente em sistemas de refrigeração industrial. A sua obtenção via reacção catalítica em meio gasoso baseado no processo Haber-Bosch é o método mais utilizado. Com base nos dados recolhidos e diagramas de processos relativos à produção de amoníaco foi desenvolvido uma folha de simulação que per...

  14. Taponamiento cardíaco secundario a carcinoma papilar esclerosante difuso de tiroides

    Verónica Riva

    2011-12-01

    Full Text Available El carcinoma papilar, variante esclerosante difusa, corresponde al 2% de todos los carcinomas papilares de la tiroides. Se caracteriza por comprometer de manera difusa y bilateral a la glándula tiroides. Clínicamente se manifiesta con metástasis ganglionares y pulmonares, afectando predominantemente a mujeres jóvenes. Se describe un caso de taponamiento cardíaco como presentación inicial de un carcinoma papilar de tiroides variante esclerosante difusa. Una mujer de 32 años concurrió al servicio de emergencias médicas refiriendo epigastralgia y tos seca. Durante el examen físico se constató hipotensión arterial, taquicardia y ruidos cardíacos disminuidos. Se realizó un ecocardiograma, observándose derrame pericárdico. Por medio de una pericardiocentesis se obtuvo líquido pericárdico, cuyo análisis mostró células neoplásicas. Durante la evolución la paciente presentó recurrencia del derrame pericárdico por lo que se realizó una ventana pleuropericárdica, detectándose durante la cirugía una lesión nodular subpleural, la cual fue biopsiada e informada posteriormente como una metástasis de carcinoma papilar vinculable a origen tiroideo. Se realizó una tiroidectomía total con linfadenectomía cervical bilateral. El diagnóstico final fue carcinoma papilar, variante esclerosante difusa. Esta variante infiltra el tejido conectivo de los espacios interfoliculares, simulando una tiroiditis y se caracteriza por una permeación vascular temprana. En oposición a la variante clásica, la esclerosante difusa presenta mayor agresividad y mayor tasa de recurrencia. El carcinoma papilar de tiroides debe tenerse presente como diagnóstico diferencial en nuestro medio, en todas aquellas lesiones neoplásicas papilares metastásicas, más aún si se trata de mujeres jóvenes.

  15. No ROI in ACO. Risk, expense of Medicare program has most for-profit groups shying away.

    Kutscher, Beth

    2012-04-23

    For-profit healthcare companies aren't beating down the door to get in on Medicare ACOs. Several of the big chains say there is too much uncertainty about the experiment, and they're waiting to see how the program evolves. One company on the sideline is Capella Healthcare. Chairman and CEO Daniel Slipkovich, left, says there is a potential for high patient dropout rates and risks in population management. PMID:22571000

  16. Eight reasons payer interoperability and data sharing are essential in ACOs. Interoperability standards could be a prerequisite to measuring care.

    Mookencherry, Shefali

    2012-01-01

    It makes strategic and business sense for payers and providers to collaborate on how to take substantial cost out of the healthcare delivery system. Acting independently, neither medical groups, hospitals nor health plans have the optimal mix of resources and incentives to significantly reduce costs. Payers have core assets such as marketing, claims data, claims processing, reimbursement systems and capital. It would be cost prohibitive for all but the largest providers to develop these capabilities in order to compete directly with insurers. Likewise, medical groups and hospitals are positioned to foster financial interdependence among providers and coordinate the continuum of patient illnesses and care settings. Payers and providers should commit to reasonable clinical and cost goals, and share resources to minimize expenses and financial risks. It is in the interest of payers to work closely with providers on risk-management strategies because insurers need synergy with ACOs to remain cost competitive. It is in the interest of ACOs to work collaboratively with payers early on to develop reasonable and effective performance benchmarks. Hence, it is essential to have payer interoperability and data sharing integrated in an ACO model. PMID:22352172

  17. 向日葵ACC氧化酶基因(HaACO1)的克隆及表达分析%Cloning and Expression Analysis of ACC Oxidase Gene (HaACO1) from Sunflower (Helianthus annuus L.)

    孙瑞芬; 张艳芳; 郭树春; 于海峰; 李素萍; 乔慧蕾; 聂惠; 安玉麟

    2015-01-01

    目的:克隆向日葵中的ACC氧化酶基因(HaACO1),并对其进行生物信息学分析及盐胁迫表达分析,为理解向日葵ACC氧化酶生理功能并加强对ACO基因的利用奠定基础.方法:以前期从盐胁迫的内葵杂4号根中获得的ACC氧化酶基因片段4-4-7TDF(KM823963)为基础,通过RT-PCR和5'/3' RACE技术克隆ACO基因的全长cDNA序列,利用生物信息学软件对获得的eDNA序列及编码的蛋白质序列进行分析.同时采用PCR方法克隆基因组DNA(genemic DNA,gDNA)序列,并对其进行结构分析.利用实时荧光定量PCR分析NaCl胁迫下向日葵根、下胚轴、叶中HaACO1的表达量和不同NaCl浓度及不同胁迫时间下根中HaACO1的表达量.结果:HaACO1的cDNA序列全长为1 135bp,其开放阅读框为942bp,编码313个氨基酸.预测其分子质量和等电点分别为35.84kDa和5.13,基因登录号为KP966508.HaACO1与已报道的多种植物的ACO基因核苷酸序列及其推导的氨基酸序列有较高的相似性,分别为76% ~ 83%和77% ~88%.gDNA起始密码子至终止密码子序列长1 018bp,包含2个外显子和1个内含子,基因登录号为KP988289.实时荧光定量PCR分析表明向日葵HaACO1在不同器官及不同NaCl浓度、不同时间诱导下存在特异性表达差异.结论:获得的向日葵HaACO1是植物ACO家族成员之一,该基因应答盐胁迫具有独特的表达模式.

  18. Task Scheduling problem in distributed systems considering communication cost and precedence by population-based ACO

    Hossein Erfani

    2012-09-01

    Full Text Available With regard to the fact of the rapid growth of distributed systems and their large spectrum of usage of proposing and representing controlling solutions and optimization of task execution procedures is one of the most important issues. Task scheduling in distributed systems has determining role in improving efficiency in applications such as communication, routing, production plans and project management. The most important issues of good schedule are minimizing makespan and average of waiting time. However, the recent and previous effort usually focused on minimizing makespan. This article presents and analyze a new method based on Ant Colony Optimization (ACO algorithm with considerations to precedence and communication cost for task scheduling problem. In the mentioned method in addition to optimization of finish time, average of waiting time and number of needed processors are also optimized. In this method, by using of a new heuristic list, an algorithm based on ant colony is proposed. The results obtained in comparison with the latest similar models of random search algorithms, proves the higher efficiency of algorithm.

  19. The cluster lens ACO 1703: redshift contrast and the inner profile

    Saha, Prasenjit

    2008-01-01

    ACO 1703 is a cluster recently found to have a variety of strongly lensed objects: there is a quintuply-imaged system at z=0.888 and several other lensed objects from z=2.2 to 3.0 (the cluster itself is at z=0.28). It is not difficult to model the lens, as previous work has already done. However, lens models are generically non-unique. We generate ensembles of models to explore the non-uniqueness. When the full range of source redshifts is included, all models are close to \\rho \\propto r^{-1} out to 200 kpc. But if the quint is omitted, both shallower and steeper models (e.g., \\rho \\propto r^{-2}) are possible. The reason is that the redshift contrast between the quint and the other sources gives a good measurement of the enclosed mass at two different radii, thus providing a good estimate of the mass profile in between. This result supports universal profiles and explains why single-model approaches can give conflicting results. The mass map itself is elongated in the NW-SE direction, like the galaxy distrib...

  20. NASA GES DISC support of CO2 Data from OCO-2, ACOS, and AIRS

    Wei, Jennifer C; Vollmer, Bruce E.; Savtchenko, Andrey K.; Hearty, Thomas J; Albayrak, Rustem Arif; Deshong, Barbara E.

    2013-01-01

    NASA Goddard Earth Sciences Data and Information Services Centers (GES DISC) is the data center assigned to archive and distribute current AIRS, ACOS data and data from the upcoming OCO-2 mission. The GES DISC archives and supports data containing information on CO2 as well as other atmospheric composition, atmospheric dynamics, modeling and precipitation. Along with the data stewardship, an important mission of GES DISC is to facilitate access to and enhance the usability of data as well as to broaden the user base. GES DISC strives to promote the awareness of science content and novelty of the data by working with Science Team members and releasing news articles as appropriate. Analysis of events that are of interest to the general public, and that help in understanding the goals of NASA Earth Observing missions, have been among most popular practices.Users have unrestricted access to a user-friendly search interface, Mirador, that allows temporal, spatial, keyword and event searches, as well as an ontology-driven drill down. Variable subsetting, format conversion, quality screening, and quick browse, are among the services available in Mirador. The majority of the GES DISC data are also accessible through OPeNDAP (Open-source Project for a Network Data Access Protocol) and WMS (Web Map Service). These services add more options for specialized subsetting, format conversion, image viewing and contributing to data interoperability.

  1. REGISTRO DE PARO CARDÍACO EN EL ADULTO Registries of outer hospital cardiac arrest in Bogotta-Colombia

    Ricardo Navarro Vargas

    2005-07-01

    Full Text Available En nuestro país no hay un registro estandarizado de los eventos cardíacos que requieren reanimación cerebro-cardio-pulmonar (RCCP siguiendo los lineamientos "Utstein". El propósito de este estudio fue determinar la calidad de los registros extrahospitalarios de paro cardíaco en el adulto, en Bogotá-Colombia. Entre enero y marzo de 2005 se realizó un análisis retrospectivo de los casos que correspondieron a paro cardíaco en el adulto atendidos por el "Centro Regulador de Urgencias del Distrito (CRU". El estudio reveló un registro deficiente de los eventos que requirieron RCCP realizados a nivel prehospitalario, e identificó al trauma como causa de paro cardíaco en 22% de los casos, una cifra particularmente elevada si se compara con los reportes mundiales, que oscilan entre 5% y 8%. Recomienda la estandarización del registro de paro cardíaco en el adulto, para lo cual se sugiere utilizar el formato de registro que sigue los lineamientos "Utstein".There is not a standardized registry form of cardiac events requiring cardiopulmonary resuscitation (CPR in our country such as the Utstein style. The purpose of this study was to determine the quality of the registries of out-ofhospital cardiac arrests in Bogotá-Colombia. A retrospective survey of registries of cardiac events assisted by a regulatory center "Centro Regulador de Urgencias del Distrito (CRU" was conducted, between January and March, 2005. The study reveals a poor registry of outof-hospital cardiac arrest in Bogotá-Colombia, and identifies trauma as the cause of cardiac arrest in 22% of cases, a particularly high figure compared with 5-8% registered worldwide. Recommend the standardization of the registry form of out-of-hospital cardiac arrest and suggest to use the "uniform reporting of data following cardiac arrest - the Utstein style". The registry forms are shown in appendix 1-2. Suggestions are welcome.

  2. Qualidade de vida de pacientes submetidos ao transplante cardíaco: aplicação da escala Whoqol-Bref Calidad de vida de pacientes sometidos a transplante cardíaco: aplicación de la escala Whoqol-Bref Quality of life of patients that had a heart transplant: application of Whoqol-Bref scale

    Maria Isis Freire de Aguiar; Deisiana Rios Farias; Mabel Leite Pinheiro; Emília Soares Chaves; Isaura Letícia Tavares Palmeira Rolim; Paulo César de Almeida

    2011-01-01

    FUNDAMENTO: O sucesso do transplante cardíaco significa garantir a sobrevida dos pacientes com cardiopatia e permitir-lhes desenvolver suas atividades diárias. O transplante cardíaco apresenta-se como a primeira opção de tratamento na falência cardíaca, representando um aumento de sobrevida e qualidade de vida dos transplantados. OBJETIVO: Avaliar a qualidade de vida de pacientes submetidos ao transplante cardíaco através da aplicação de uma escala padronizada (Whoqol-Bref). MÉTODOS: Estudo e...

  3. Transplante cardíaco humano: experiência inicial Human cardiac transplant: initial experience

    Noedir A. G Stolf

    1986-12-01

    Full Text Available No Instituto do Coração, de março de 1985 a fevereiro de 1986,11 pacientes foram submetidos a transplante cardíaco ortotópico. Eram todos do sexo masculino, com idade variando de 39 a 54 anos; 6 com cardiopatia isquémica, 4 com cardiomiopatia dilatada e um com cardiomiopatia chagásica. Foi realizado estudo hemodinâmico através de catéter de Swan-Ganz, no pré-operatório, no pós-operatório, após estabilização na unidade de recuperação, e trinta ou mais dias após o transplante. Os dados mostram melhora progressiva em relação ao índice cardíaco, pressão em artéria pulmonar, pressão de capilar pulmonar, resistência vascular pulmonar e resistência vascular sistêmica. Três dos 11 pacientes apresentaram disfunção renal transitória no pós-operatório imediato e que regrediram até o 15º dia, enquanto que 2 pacientes apresentaram aumento moderado da creatinina plasmática. Apenas 3 pacientes não apresentaram qualquer episódio de rejeição; nos demais, esses episódios foram um diagnóstico histológico sem repercussões clínicas. Complicações infecciosas ocorreram em 9 pacientes e foram de fácil controle clínico. No pós-operatório tardio, a hipertensão esteve presente em 8 pacientes, sendo mais acentuada em 2 deles. Não houve óbitos, nesta série de pacientes; todos estão assintomáticos e os 6 primeiros estão trabalhando.At the Instituto do Cora��ão, University of São Paulo Medical School, 11 patients were submitted to heart transplantation from march 1985 up to february 1986. All were male, with ages of 39-59 years, 6 with coronary heart disease, 4 with dilated cardiomyopathy and 1 with Chagas cardiomyopathy. The patients were studied hemodynamically with a Swan-Ganz catheter pre-operatively, at the arrival in the intensive care unit, in the first postoperative day and 30 or more days after the transplant. The data showed that there was a progressive increase of cardiac index and decreases of

  4. Changes in oxidative stress in transgenic RNAi ACO1 tomato fruit during ripening

    Eglous, Najat Mohamed; Ali, Zainon Mohd; Hassan, Maizom; Zainal, Zamri

    2013-11-01

    Tomato (Solanum Lycopersicum L.) is the second most cultivated vegetable in the world and widely used as a system for studying the role of ethylene during fruit ripening. Our objective was to study the oxidative stress and antioxidative metabolism during ripening of non transgenic tomato and transgenic line-21 tomato which reduced ethylene. The line-21 of transgenic tomato plants (RNAi ACO1) had lower ethylene production and longer shelf-life more than 32 days as compared to the wild-type fruits which have very short shelf-life. In this study, tomato fruit were divided into five different stages (MG: mature green 5%, B: breaker 25%, T: turning 50%, O: orange75%, RR: red ripe100%). The activity of lipoxygenase (LOX) and lipid peroxidation (MDA) were measured to assess changes in oxidative stress. The LOX activity and MDA content decreased significantly obtaining 2.6-fold and 1.2-fold, respectively, as compared to the wild type fruit. However, superoxide dismutase (SOD) and catalase (CAT) activities were increased to 1.9 and 1.2 folds from the mature green to the fully ripe stage in transgenic tomatoes. Furthermore, the wild type tomato increases 1.3 in SOD and 1.6 in CAT activities. The overall results indicate that the wild type tomato fruit showed a faster rate of ripening, parallel to decline in the rate of enzymatic antioxidative systems as compared to the transgenic line-21 tomato fruit. In addition, the results show that the antioxidant capacity is improved during the ripening process and is accompanied by an increase in the oxidative stress.

  5. SmartPATH: An Efficient Hybrid ACO-GA Algorithm for Solving the Global Path Planning Problem of Mobile Robots

    Imen Châari

    2014-07-01

    Full Text Available Path planning is a fundamental optimization problem that is crucial for the navigation of a mobile robot. Among the vast array of optimization approaches, we focus in this paper on Ant Colony Optimization (ACO and Genetic Algorithms (GA for solving the global path planning problem in a static environment, considering their effectiveness in solving such a problem. Our objective is to design an efficient hybrid algorithm that takes profit of the advantages of both ACO and GA approaches for the sake of maximizing the chance to find the optimal path even under real-time constraints. In this paper, we present smartPATH, a new hybrid ACO-GA algorithm that relies on the combination of an improved ACO algorithm (IACO for efficient and fast path selection, and a modified crossover operator to reduce the risk of falling into a local minimum. We demonstrate through extensive simulations that smartPATH outperforms classical ACO (CACO, GA algorithms. It also outperforms the Dijkstra exact method in solving the path planning problem for large graph environments. It improves the solution quality up to 57% in comparison with CACO and reduces the execution time up to 83% as compared to Dijkstra for large and dense graphs. In addition, the experimental results on a real robot shows that smartPATH finds the optimal path with a probability up to 80% with a small gap not exceeding 1m in 98%.

  6. Sedação com sufentanil e clonidina em pacientes submetidos a cateterismo cardíaco

    Anita Perpetua Carvalho Rocha

    2011-03-01

    Full Text Available FUNDAMENTO: A sedação para a realização de cateterismo cardíaco tem sido alvo de preocupação. Benzodiazepínicos, agonistas alfa-2 adrenérgicos e opioides são utilizados para esse fim, entretanto, cada um destes medicamentos possui vantagens e desvantagens. OBJETIVO: Avaliar a eficácia do sufentanil e da clonidina como sedativos em pacientes submetidos a cateterismo cardíaco, observando o impacto dos mesmos sobre os parâmetros hemodinâmicos e respiratórios, a presença de efeitos colaterais, além da satisfação do paciente e do hemodinamicista com o exame. MÉTODOS: Trata-se de um ensaio clínico prospectivo, duplo-cego, randomizado e controlado, que envolveu 60 pacientes que receberam 0,1 µg/kg de sufentanil ou 0,5 µg/kg de clonidina antes da realização do cateterismo cardíaco. O escore de sedação segundo a escala de Ramsay, a necessidade de utilização de midazolam, os efeitos colaterais, os parâmetros hemodinâmicos e respiratórios foram registrados, sendo os dados analisados em 06 diferentes momentos. RESULTADOS: O comportamento da pressão arterial, da frequência cardíaca e da frequência respiratória foi semelhante nos dois grupos, entretanto, no momento 2, os pacientes do grupo sufentanil (Grupo S apresentaram menor escore de sedação segundo a escala de Ramsay, e a saturação periférica da oxihemoglobina foi menor que o grupo clonidina (Grupo C no momento 6. Os pacientes do Grupo S apresentaram maior incidência de náusea e vômito pós-operatório que os pacientes do Grupo C. A satisfação dos pacientes foi maior no grupo clonidina. Os hemodinamicistas mostraram-se satisfeitos nos dois grupos. CONCLUSÃO: O sufentanil e a clonidina foram efetivos como sedativos em pacientes submetidos a cateterismo cardíaco.

  7. Acute Care of At-Risk Newborns (ACoRN): quantitative and qualitative educational evaluation of the program in a region of China

    Singhal Nalini; Lockyer Jocelyn; Fidler Herta; Aziz Khalid; McMillan Douglas; Qiu Xiangming; Ma Xiaolu; Du Lizhong; Lee Shoo K

    2012-01-01

    Abstract Background The Acute Care of at-Risk Newborns (ACoRN) program was developed in Canada for trained health care providers for the identification and management of newborns who are at-risk and/or become unwell in the first few hours or days after birth. The ACoRN process follows an 8-step framework that enables the evaluation and management of babies irrespective of the experience or expertise of the caregiving individual or team. This study assesses the applicability of the program to ...

  8. Manejo de las dislipidemias en pacientes cardíacos trasplantados. Hallazgos sobre nuevos factores de riesgo

    Walter Masson

    2008-01-01

    Full Text Available En pacientes cardíacos trasplantados, el desarrollo de enfermedad vascular coronaria es una complicación frecuente y la dislipidemia es uno de los predictores más importantes. Los inmunosupresores predisponen a las dislipidemias y dificultan la utilización de hipolipemiantes. En este grupo particular de pacientes se recomienda alcanzar las metas terapéuticas de prevención secundaria. Las estatinas son los hipolipemiantes de elección. No existen recomendaciones claras sobre nuevos factores de riesgo, como la homocisteína y la lipoproteína (a [Lp(a].Con el objetivo de conocer el perfil lipídico, la prevalencia de homocisteinemia y de Lp(a elevadas, el cumplimiento de las metas terapéuticas y la tolerancia a la medicación, se incluyeron en el estudio 23 pacientes cardíacos trasplantados. Los resultados mostraron que el cumplimiento de las metas lipídicas fue aceptable y que el 65% recibía tratamiento hipolipemiante. El uso de estatinas fue seguro. Se encontró una prevalencia alta de homocisteína y Lp(a elevadas. Su implicación en la modificación del tratamiento se desconoce.

  9. Transient absorption spectroscopy in biology using the Super-ACO storage ring FEL and the synchrotron radiation combination

    Renault, E; De Ninno, G; Garzella, D; Hirsch, M; Nahon, L; Nutarelli, D

    2001-01-01

    The Super-ACO storage ring FEL, covering the UV range down to 300 nm with a high average power (300 mW at 350 nm) together with a high stability and long lifetime, is a unique tool for the performance of users applications. We present here the first pump-probe two color experiments on biological species using a storage ring FEL coupled to the synchrotron radiation. The intense UV pulse of the Super-ACO FEL is used to prepare a high initial concentration of chromophores in their first singlet electronic excited state. The nearby bending magnet synchrotron radiation provides, on the other hand a pulsed, white light continuum (UV-IR), naturally synchronized with the FEL pulses and used to probe the photochemical subsequent events and the associated transient species. We have demonstrated the feasibility with a dye molecule (POPOP) observing a two-color effect, signature of excited state absorption and a temporal signature with Acridine. Applications on various chromophores of biological interest are carried out,...

  10. Interacciones entre dispositivos cardíacos implantables y modalidades fisioterapéuticas: ¿Mito o realidad?

    Genevieve C. Digby

    2011-04-01

    Full Text Available La fisioterapia se ha transformado en una especialidad que claramente incide en la calidad de vida de nuestros pacientes. En poblaciones añosas, el uso de fisioterapia incluye múltiples modalidades para un alto número de distintas enfermedades. Varios informes sobre posibles interacciones negativas entre las distintas modalidades de fisioterapia y los dispositivos cardíacos implantables (marcapasos y cardiodesfibriladores han sido publicados en los últimos aňos. A pesar de ello, existe muy poca evidencia y guías precisas para identificar cuáles son las modalidades de fisioterapia seguras a utilizar en esta población de pacientes. En la siguiente revisión, nos propusimos resumir las interacciones documentadas entre fisioterapia y dispositivos cardíacos implantables (DCI, discutir el estándar actual de estas prácticas e identificar las principales consideraciones que existen desde la perspectiva de un servicio de electrofisiología cardíaca, para el tratamiento adecuado en estos pacientes. Finalmente, abogamos por fortalecer la colaboración entre fisioterapeutas y electrofisiólogos, con el fin de asegurar una óptima y segura atención de este grupo de pacientes.

  11. A Web-Based Egg-Quality Expert Advisory System using Rule Based and Ant Colony (ACO Optimization Algorithms

    J. Anitha

    2010-10-01

    Full Text Available This paper deals with the development of Web based online expert systems using Evolutionary Algorithms. An expert system is a computer application that performs a task that would otherwise be performed by a human expert. Here one of the evolutionary algorithms (ACO Algorithm is considered to find a good match of symptoms in the database. In the present paper, Ant Colony Optimization1 (ACO algorithm has been taken as the base and the concept of optimization is included, so that the new algorithm mainly focuses on the determination of the quality of eggs in the poultry farms. At first, the symptoms provided by the user are processed by a rule based expert system for identifying the quality of the eggs. If the rules required for processing the data by the above are not present in the database, then the system automatically calls the machine learning algorithm technique. As a whole, the system results good optimized solution for recognizing the quality and viruses if any affected to eggs in poultry farms. And corresponding treatments to the viruses may also be suggested to the users. This expert system is designed with JSP as front end and MySQL as backend.

  12. Imunocitomonitorização em pacientes transplantados cardíacos Immunocytomonitorization in patients submitted to cardiac transplantation

    Ricardo Manrique

    1990-04-01

    Full Text Available A técnica de Imunocitomonitorização (CIM - Cytologrcal and Immunologic Monitoring, fundamenta-se na avaliação de mudanças nas subpopulações de linfócitos e seus precursores celulares, durante o processo rejeição aguda. O método avalia a ativação precoce pela contagem do número de: linfócitos ativados, linfoblastos e prolinfócitos (aqui chamados em conjunto de linfócitos ativos, quando esses se apresentam acima do limite superior normal. Utilizamos essa técnica para seguimento e controle da atividade da imunologia celular em 9 pacientes transplantados cardíacos. Também foram submetidos ao CIM para verificar a faixa de normalidade de ativação linfocítica 20 voluntários normais e cinco pacientes candidatos ao transplante cardíaco. Ambos os grupos não tinham antecedentes de quadro de infecção ou alteração imunológica. Para obtenção do controle positivo, testamos 10 pacientes com infecção bacteriana ou virai, previamente diagnosticados por exames bacterianos e/ou sorológicos. Foram observados valores de 1,8% de linfócitos ativos nos indivíduos normais e 3,2% nos candidatos ao transplante cardíaco. Dos 63 testes realizados nos transplantados cardíacos, quatro deles se mostraram positivos, onde três desses tratavam-se de casos de infecção e um confirmado como processo de rejeição aguda em evolução. O tempo médio necessário para a realização da CIM foi de aproximadamente duas horas. A técnica utiliza mostrou-se valiosa no reconhecimento imunológico dos pacientes transplantados cardíacos, pela sua sensibilidade diagnostica, baixo custo e rapidez.The immunocytomonitorization technique (CIM - Cytological and Immunologic Monitoring is based on assessment of changes in the subpopulations of lyphocyte and their precursor cells, while under the acute rejection. The method assesses the precocious activation by counting the number of the lymphocytes normal and actives, lymphoblasts and prolymphocytes (here

  13. Intelligent Search Method Based ACO Techniques for a Multistage Decision Problem EDP/LFP

    Mostefa RAHLI

    2006-07-01

    the algorithm getting to him a rate preferably more or less justifiable. In operational research, this subject is known under the name of CPO [14] (combinatory problem optimization.The choice of a numerical method to use for a merged case study and calculation of the LFP/Fitting/EDP what is [7, 8, 9, 10, 18, 19, 20] (in theoretical form of a problem compensates the final decision to adopt and a strategy of optimal production (which is a practical problem form and the final task most wanted.Each method is imposed by:· The algorithm complexity.· In an application gathering all calculations, the number of uses of method compared to the total number of later issues.· The maximum number of iterations for a given use.· The maximum iterations count allowed for this algorithm kind.· The limitations of the algorithm such as: applicability of a method (algorithm adapted or not to the problem; does the problem constrained or not; problem dimension or order N (N ≤ Nmax; the algorithm stability.It's well-known that for an approached calculation method, the propagation of errors strongly conditions the need of making its adequate choice and if it can be adopted compared to others for the same area.More is the number of the elementary operations is large more the final result misses precision and especially if the finality of the study is a responsible decision to make and a satisfaction of constraints and multiple conditions. Our study proposes an inference based solution (AI with the use of ACO technique (Ant colony Optimization2.

  14. Meta-heurística ACO (Ant Colony Optimization) para la resolución de problemas en líneas de producción

    Bautista Valhondo, Joaquín; Bretón Blas, Javier; Fernández Ros, José Antonio; De la Rosa Herrero, Marcela

    2000-01-01

    La meta-heurística ACO (Ant Colony Optimization) es un procedimiento heurístico para la resolución de problemas de optimización discreta basado en el comportamiento de las hormigas. Sus principales características son: (1) la utilización de

  15. Hybridisations Of Simulated Annealing And Modified Simplex Algorithms On A Path Of Steepest Ascent With Multi-Response For Optimal Parameter Settings Of ACO

    Luangpaiboon, P.

    2009-10-01

    Many entrepreneurs face to extreme conditions for instances; costs, quality, sales and services. Moreover, technology has always been intertwined with our demands. Then almost manufacturers or assembling lines adopt it and come out with more complicated process inevitably. At this stage, products and service improvement need to be shifted from competitors with sustainability. So, a simulated process optimisation is an alternative way for solving huge and complex problems. Metaheuristics are sequential processes that perform exploration and exploitation in the solution space aiming to efficiently find near optimal solutions with natural intelligence as a source of inspiration. One of the most well-known metaheuristics is called Ant Colony Optimisation, ACO. This paper is conducted to give an aid in complicatedness of using ACO in terms of its parameters: number of iterations, ants and moves. Proper levels of these parameters are analysed on eight noisy continuous non-linear continuous response surfaces. Considering the solution space in a specified region, some surfaces contain global optimum and multiple local optimums and some are with a curved ridge. ACO parameters are determined through hybridisations of Modified Simplex and Simulated Annealing methods on the path of Steepest Ascent, SAM. SAM was introduced to recommend preferable levels of ACO parameters via statistically significant regression analysis and Taguchi's signal to noise ratio. Other performance achievements include minimax and mean squared error measures. A series of computational experiments using each algorithm were conducted. Experimental results were analysed in terms of mean, design points and best so far solutions. It was found that results obtained from a hybridisation with stochastic procedures of Simulated Annealing method were better than that using Modified Simplex algorithm. However, the average execution time of experimental runs and number of design points using hybridisations were

  16. Certeza diagnóstica en la mortalidad de una población de pacientes con trasplante cardíaco

    Marcos Amuchástegui

    2008-01-01

    Full Text Available RESUMENIntroducciónA pesar de que la morbimortalidad en el trasplante cardíaco ha sido motivo de extensoanálisis, la mayoría de los estudios y registros de mortalidad en pacientes trasplantados sebasan sobre datos clínicos. En la bibliografía existen comunicaciones aisladas de autopsiasen pacientes con trasplante cardíaco.ObjetivoDeterminar la importancia de la realización de estudios anatomopatológicos para el diagnósticode causa de muerte en un programa de trasplante cardíaco.Material y métodosSe incluyeron todos los pacientes con trasplante cardíaco fallecidos entre enero 1990 y enero2005. El diagnóstico definitivo de la causa de muerte fue corroborado por autopsia obiopsia de órgano sólido. Las causas de muerte evaluadas fueron falla precoz del injerto,rechazo celular, infección, enfermedad vascular del injerto, neoplasia y otros.ResultadosDurante el período en estudio 73 pacientes fueron sometidos a trasplante cardíaco; de ellos,fallecieron 31. Se obtuvieron 12 autopsias y 7 biopsias de órgano sólido que certificaron lacausa de muerte (61%. La causa de muerte más frecuente fue el rechazo celular mayor degrado III. En el 12,9%, la anatomía patológica difirió de la sospecha clínica de la causa demuerte.ConclusiónLa información clinicopatológica derivada de estudios post mortem es un indicador de nuestrarealidad asistencial y se constituye en un pilar fundamental para el conocimiento y elmanejo futuro de los pacientes trasplantados, por lo que consideramos que la realización deautopsias en estos pacientes es de vital importancia.REV ARGENT CARDIOL 2008;76:292-294.

  17. Certeza diagnóstica en la mortalidad de una población de pacientes con trasplante cardíaco

    Marcos Amuchástegui (h,

    2006-01-01

    Full Text Available Introducción A pesar de que la morbimortalidad en el trasplante cardíaco ha sido motivo de extenso análisis, la mayoría de los estudios y registros de mortalidad en pacientes trasplantados se basan sobre datos clínicos. En la bibliografía existen comunicaciones aisladas de autopsias en pacientes con trasplante cardíaco.Objetivo Determinar la importancia de la realización de estudios anatomopatológicos para el diagnóstico de causa de muerte en un programa de trasplante cardíaco.Material y métodosSe incluyeron todos los pacientes con trasplante cardíaco fallecidos entre enero 1990 y enero 2005. El diagnóstico definitivo de la causa de muerte fue corroborado por autopsia o biopsia de órgano sólido. Las causas de muerte evaluadas fueron falla precoz del injerto, rechazo celular, infección, enfermedad vascular del injerto, neoplasia y otros.ResultadosDurante el período en estudio 73 pacientes fueron sometidos a trasplante cardíaco; de ellos, fallecieron 31. Se obtuvieron 12 autopsias y 7 biopsias de órgano sólido que certificaron la causa de muerte (61%. La causa de muerte más frecuente fue el rechazo celular mayor de grado III. En el 12,9%, la anatomía patológica difirió de la sospecha clínica de la causa de muerte.ConclusiónLa información clinicopatológica derivada de estudios post mortem es un indicador de nuestra realidad asistencial y se constituye en un pilar fundamental para el conocimiento y el manejo futuro de los pacientes trasplantados, por lo que consideramos que la realización de autopsias en estos pacientes es de vital importancia.

  18. El calcio en los miocitos cardíacos y su papel en las miocardiopatías.

    Guido Ulate Montero; Adriana Ulate Campos

    2006-01-01

    El papel que desempeña el calcio en los miocitos cardíacos abarca un gran número de funciones, desde su rol en el acoplamiento excitación-ccontracción hasta su papel de segundo mensajero en las diversas vías de señalización, algunas de las cuales se activan en procesos que afectan la integridad del tejido miocárdico y que tienen que ver con el crecimiento y la apoptosis de los miocitos y que al final, son los que determinan la evolución de la mayoría de las cardiomiopatías. En esta revisión s...

  19. CO2 Measurements from Space: Lessons Learned from the Collaboration between the ACOS/OCO-2 and GOSAT Teams

    Crisp, D.; Eldering, A.; Gunson, M. R.

    2012-12-01

    The NASA Orbiting Carbon Observatory (OCO) and the Japanese Greenhouse gases Observing SATellite (GOSAT) were the first two missions designed to collect space-based observations of the column-averaged CO2 dry air mole fraction, XCO2, with the sensitivity, coverage, and resolution needed to quantify CO2 fluxes on regional scales over the globe. The OCO and GOSAT teams formed a close collaboration during the development phases of these missions. After the loss of OCO, the GOSAT project team invited the OCO team to contribute to the analysis of measurements collected by the GOSAT Thermal And Near infrared Sensor for carbon Observations-Fourier Transform Spectrometer (TANSO-FTS). NASA responded by reformulating the OCO science team under the Atmospheric CO2 Observations from Space (ACOS) task to exploit this opportunity. This collaboration is providing an independent GOSAT XCO2 product, and valuable insights into the retrieval algorithms, calibration methods, and validation techniques that are being developed to analyze data anticipated the NASA Orbiting Carbon Observatory-2 (OCO-2). The ACOS/OCO-2 and GOSAT teams have conducted four, joint, vicarious calibration campaigns at Railroad Valley, Nevada to track the long-term radiometric performance of the TANSO-FTS instrument. The methods used in these campaigns evolved from those used to characterize the radiometric performance of high spatial resolution, imaging spectroradiometers. For TANSO-FTS, the conventional, surface based radiometric measurements have been augmented with surface and aircraft measurements of atmospheric temperature and trace gas profiles, as well as surface observations from MODIS and ASTER to characterize spatial variations of the surface reflectance within the (relatively large) sounding footprints. Similar methods will be needed for OCO-2. The ACOS/OCO-2 retrieval algorithm and associated data screening methods have been modified to estimate XCO2 from TANSO-FTS observations. Comparisons of TANSO

  20. Transplante cardíaco em portadora de endomiocardiofibrose Heart transplantation in a patient with endomyocardial fibrosis

    Humberto F.G. de Freitas

    2005-01-01

    Full Text Available A endomiocardiofibrose é uma doença comum em países tropicais, particularmente Uganda e Nigéria, e pode acometer tanto o ventrículo esquerdo como direito, gerando uma insuficiência cardíaca restritiva que, além dos sintomas clássicos, manifesta-se por ascite desproporcional ao edema periférico. Apresentamos o caso de uma portadora de endomiocardiofibrose refratária ao tratamento clínico, submetida ao tratamento cirúrgico com melhora clínica por curto período, voltando a apresentar sintomas incapacitantes três meses após a cirurgia de ressecção de fibrose endomiocárdica e plastia tricúspide. A paciente foi então submetida a transplante cardíaco ortotópico bicaval, com boa evolução clínica. É o primeiro caso de transplante cardíaco nesta doença, mostrando-se uma alternativa de tratamento promissora.Endomyocardial fibrosis is a common disease in tropical countries, particularly Uganda and Nigeria. It may affect the right and left ventricles, creating restrictive heart failure, which, in addition to the classical symptoms, manifests as ascites disproportional to peripheral edema. We report the case of a female patient with endomyocardial fibrosis refractory to clinical treatment, who underwent surgical treatment with clinical improvement for a short period. Three months after the surgery for resection of the endomyocardial fibrosis and tricuspid valvuloplasty, the disabling symptoms reappeared. Then the patient underwent bicaval orthotopic heart transplantation, which had a good clinical outcome. This was the first case of heart transplantation for the treatment of endomyocardial fibrosis, which proved to be a promising alternative.

  1. Achados oftalmológicos em pacientes que receberam transplante cardíaco Ophthalmologic findings in cardiac transplant recipients

    Cecília Sales Pires

    2007-10-01

    Full Text Available OBJETIVO: Avaliar os achados oculares, pelo exame oftalmológico, em indivíduos que receberam transplante cardíaco, buscando especialmente investigar possíveis alterações na camada de fibras nervosas da retina com polarímetro de varredura a laser. MÉTODOS: Foram estudados 15 indivíduos que receberam transplante cardíaco no período de setembro de 2003 a julho de 2004. Todos foram submetidos a exame que constava de acuidade visual para longe (AVL, biomicroscopia, tonometria e fundoscopia. Onze pacientes foram submetidos ao analisador de fibras nervosas GDx. Doze eram do sexo masculino e a média da idade foi de 55,0 ± 13,5 anos. O tempo decorrido desde o transplante variou de 3 a 74 meses, com média de 29,7 ± 20,8 meses. RESULTADOS: A AVL com melhor correção foi igual ou melhor do que 20/40 em todos os pacientes. Em um deles observou-se a presença de catarata subcapsular posterior; em outro, nubéculas na córnea secundárias a quadro de herpes zoster. À fundoscopia pôde-se observar lesão cicatrizada sugestiva de retinocoroidite em um paciente. As alterações observadas à biomicroscopia e à fundoscopia eram esperadas devido à imunossupressão subseqüente ao transplante. Ao GDx observou-se perda de fibras da camada de fibras nervosas da retina superior em 12 dos 22 olhos avaliados. CONCLUSÃO: Os resultados apóiam a suposição de que antes ou durante o transplante cardíaco tenha havido diminuição no aporte de oxigênio à circulação retiniana, levando a perda parcial de fibras da retina.PURPOSE: To evaluate findings of ophthalmologic examinations in cardiac transplant recipients, searching especially for changes in the retinal nerve fiber layer by means of Scanning Laser Polarimetry. METHODS: Fifteen cardiac transplant recipients were examined from September 2003 to July 2004. All of them underwent ophthalmologic examination, which consisted of visual acuity (VA, biomicroscopy, tonometry and fundoscopy. Fiber layer

  2. El calcio en los miocitos cardíacos y su papel en las miocardiopatías.

    Guido Ulate Montero

    2006-01-01

    Full Text Available El papel que desempeña el calcio en los miocitos cardíacos abarca un gran número de funciones, desde su rol en el acoplamiento excitación-ccontracción hasta su papel de segundo mensajero en las diversas vías de señalización, algunas de las cuales se activan en procesos que afectan la integridad del tejido miocárdico y que tienen que ver con el crecimiento y la apoptosis de los miocitos y que al final, son los que determinan la evolución de la mayoría de las cardiomiopatías. En esta revisión se abordan los mecanismos fisiológicos en las células de músculo cardíaco en los que este ión juega un papel determinante y los cambios que se presentan en ciertas cardiopatías como la miocardiopatía arritmogénica del ventrículo derecho, las miocardiopatías asociadas a alteraciones en el receptor de rianodina y la miocardiopatía dilatada. Se revisa también la farmacodinamia de los agentes inotrópicos positivos que actúan sensibilizando los miofilamentos del sarcómero al calcio.The rol played by calcium in cardiomyocytes includes a great number of functions like the excitation-contraction coupling as well as a second messenger in diverse signaling pathways. Some of these pathways are activated in processes that affect the cardiac tissue integrity and also participate in cell growth and apoptosis, determining the poor prognosis that characterize the majority of the cardiomyopathies. In this review,the mechanisms inside the cardiomyocytes in which participates calcium and the pathophysiological changes observed in some cardiac diseases like arrhythmogenic right ventricular cardiomyopathy, catecholaminergic polymorphic ventricular tachycardia, idiopathic dilated cardiomyopathy, and others, are described. The action mechanism of positive inotropic drugs that act as sarcomere myofilaments sensitizers is also reviewed.

  3. Sildenafil vs. Nitroprussiato de Sódio durante Teste de Reatividade Pulmonar pré-transplante cardíaco

    Aguinaldo Figueiredo Freitas Jr

    2012-09-01

    Full Text Available FUNDAMENTO: A hipertensão pulmonar é associada ao pior prognóstico no pós-transplante cardíaco. O teste de reatividade pulmonar com Nitroprussiato de Sódio (NPS está associado a elevados índices de hipotensão arterial sistêmica, disfunção ventricular do enxerto transplantado e elevadas taxas de desqualificação para o transplante. OBJETIVO: Neste estudo, objetivou-se comparar os efeitos do Sildenafil (SIL e NPS sobre variáveis hemodinâmicas, neuro-hormonais e ecocardiográficas durante teste de reatividade pulmonar. MÉTODOS: Os pacientes foram submetidos, simultaneamente, ao cateterismo cardíaco direito, ao ecocardiograma e à dosagem de BNP e gasometria venosa, antes e após administração de NPS (1 - 2 µg/Kg/min ou SIL (100 mg, dose única. RESULTADOS: Ambos reduziram a hipertensão pulmonar, porém o nitrato promoveu hipotensão sistêmica significativa (Pressão Arterial Média - PAM: 85,2 vs. 69,8 mmHg, p < 0,001. Ambos reduziram as dimensões cardíacas e melhoraram a função cardíaca esquerda (NPS: 23,5 vs. 24,8 %, p = 0,02; SIL: 23,8 vs. 26 %, p < 0,001 e direita (SIL: 6,57 ± 2,08 vs. 8,11 ± 1,81 cm/s, p = 0,002; NPS: 6,64 ± 1,51 vs. 7,72 ± 1,44 cm/s, p = 0,003, medidas pela fração de ejeção ventricular esquerda e Doppler tecidual, respectivamente. O SIL, ao contrário do NPS, apresentou melhora no índice de saturação venosa de oxigênio, medido pela gasometria venosa. CONCLUSÃO: Sildenafil e NPS são vasodilatadores que reduzem, de forma significativa, a hipertensão pulmonar e a geometria cardíaca, além de melhorar a função biventricular. O NPS, ao contrário do SIL, esteve associado a hipotensão arterial sistêmica e piora da saturação venosa de oxigênio.

  4. L’intelligence collective dans un contexte de développement professionnel continu : ACoPé, l’exemple d’une communauté de pratique

    Pichon, Aude; Morel, Alexandre; Gassie, Brigitte; Vandenkoornhuyse, Christine; Delalande, Pascaline

    2015-01-01

    Cooperating with a view to furthering professional development, taking decisions and functioning interoperatively within a community implies working with participants committed to fostering strong relationships, reflective practice, and reaching shared understanding.The collaboration between the ACoPé educational advisors takes place within this context itself part of the wider framework of a higher education environment with intersectoral, interprofessional, interdisciplinary and inter-regio...

  5. Acute Care of At-Risk Newborns (ACoRN: quantitative and qualitative educational evaluation of the program in a region of China

    Singhal Nalini

    2012-06-01

    Full Text Available Abstract Background The Acute Care of at-Risk Newborns (ACoRN program was developed in Canada for trained health care providers for the identification and management of newborns who are at-risk and/or become unwell in the first few hours or days after birth. The ACoRN process follows an 8-step framework that enables the evaluation and management of babies irrespective of the experience or expertise of the caregiving individual or team. This study assesses the applicability of the program to Chinese pediatric practitioners. Methods Course content and educational materials were translated from English into Chinese by bilingual neonatal practitioners. Confidence and knowledge questionnaires were developed and reviewed for face and content validity by a team of ACoRN instructors. Bilingual Chinese instructors were trained at the tertiary perinatal centre in Hangzhou Zhejiang to deliver the course at 15 level II county hospitals. Participants completed pre- and post-course confidence and knowledge questionnaires and provided feedback through post-course focus groups. Results 216 physicians and nurses were trained. Confidence and knowledge relating to neonatal stabilization improved significantly following the courses. Participants rated course utility and function between 4.2 and 4.6/5 on all items. Pre/post measures of confidence were significantly correlated with post course knowledge. Focus group data supported the perceived value of the program and recommended course adjustments to include pre-course reading, and increased content related to simulation, communication skills, and management of respiratory illness and jaundice. Conclusions ACoRN, a Canadian educational program, appears to be well received by Chinese health care providers and results in improved knowledge and confidence. International program adaptation for use by health care professionals requires structured and systematic evaluation to ensure that the program meets the needs of

  6. Swarm Intelligence Based Ant Colony Optimization (ACO Approach for Maximizing the Lifetime of Heterogeneous Wireless Sensor Networks

    LingaRaj.K

    2013-11-01

    Full Text Available This paper attempts to undertake the study of maximizing the lifetime of Heterogeneous wireless sensor networks (WSNs. In wireless sensor networks, sensor nodes are typically power-constrained with limited lifetime, and thus it is necessary to know how long the network sustains its networking operations. Heterogeneous WSNs consists of different sensor devices with different capabilities. We can enhance the quality of monitoring in wireless sensor networks by increasing the coverage area. One of major issue in WSNs is finding maximum number of connected coverage. This paper proposed a Swarm Intelligence, Ant Colony Optimization (ACO based approach. Ant colony optimization algorithm provides a natural and intrinsic way of exploration of search space of coverage area. Ants communicate with their nest- mates using chemical scents known as pheromones, Based on Pheromone trail between sensor devices the shortest path is found. The methodology is based on finding the maximum number of connected covers that satisfy both sensing coverage and network connectivity. By finding the coverage area and sensing range, the network lifetime maximized and reduces the energy consumption

  7. Qualidade de vida de pacientes submetidos ao transplante cardíaco: aplicação da escala Whoqol-Bref

    Maria Isis Freire de Aguiar

    2011-01-01

    Full Text Available FUNDAMENTO: O sucesso do transplante cardíaco significa garantir a sobrevida dos pacientes com cardiopatia e permitir-lhes desenvolver suas atividades diárias. O transplante cardíaco apresenta-se como a primeira opção de tratamento na falência cardíaca, representando um aumento de sobrevida e qualidade de vida dos transplantados. OBJETIVO: Avaliar a qualidade de vida de pacientes submetidos ao transplante cardíaco através da aplicação de uma escala padronizada (Whoqol-Bref. MÉTODOS: Estudo exploratório descritivo de abordagem quantitativa, realizado com 55 pacientes submetidos ao transplante cardíaco, em um período entre o terceiro e o 103º mês, que realizam acompanhamento na Unidade de Transplante e Insuficiência Cardíaca em um Hospital de Referência em Cardiologia na cidade de Fortaleza, CE. Os dados foram coletados no período de fevereiro a abril de 2009, por meio da aplicação de um questionário padronizado pela Organização Mundial da Saúde e utilização de dados constantes nos prontuários. RESULTADOS: Com relação ao domínio físico, 62,8% e 58,3% dos pacientes, dos sexos masculino e feminino, respectivamente, estão satisfeitos. No domínio psicológico, dentre pacientes do sexo masculino, 65,1% apresentam satisfação quanto à qualidade de vida e, no sexo feminino, 58,3% encontram-se satisfeitas. No domínio das relações sociais, observou-se que, no sexo masculino, 53,5% estão muito satisfeitos, e apresentou-se um nível de satisfação de 100% no sexo feminino. No domínio do meio ambiente, 65,1% do sexo masculino encontram-se satisfeitos, e no sexo feminino, 83,3% estão satisfeitas. CONCLUSÃO: O transplante cardíaco teve bastante influência na qualidade de vida dos pacientes transplantados, pois os resultados mostram-se estatisticamente significantes no pós-transplante.

  8. Transplante cardíaco no Instituto Dante Pazzanese de Cardiologia: análise da sobrevida

    ASSEF Marco Aurélio Salles

    2001-01-01

    Full Text Available CASUÍSTICA E MÉTODOS: Foram analisados, retrospectivamente, 80 transplantes cardíacos realizados no Instituto Dante Pazzanese de Cardiologia (IDPC no período de novembro de 1991 a agosto de 2000. Houve predomínio do sexo masculino em 70% dos casos e a idade variou de 7 a 69 anos, com média de 44,8 anos. Doze (15% pacientes se encontravam em prioridade, em uso de drogas inotrópicas endovenosas no momento do transplante. As etiologias determinantes da insuficiência cardíaca congestiva grave foram: miocardiopatia dilatada idiopática em 37,5%, miocardiopatia isquêmica em 33,75%, miocardiopatia chagásica em 17,5% e outras causas em 11,25%. Foram realizados 78 transplantes ortotópicos e 2 heterotópicos. A técnica empregada foi bicaval/bipulmonar em 63,75%, atrial em 27,5%, bicaval/unipulmonar em 6,25% e heterotópico em 2,5%. A mortalidade hospitalar (30 dias foi de 18,75%. RESULTADOS: A sobrevida para o transplante ortotópico em um ano foi de 72,7%, em cinco anos 61,5% e em sete anos 56,4%. A sobrevida após o transplante foi correlacionada com as variáveis idade, causa de óbito e sexo do doador, e pelo transplante ter sido ou não a primeira cirurgia cardíaca do paciente.

  9. Aneurisma ilíaco associado a fístula arteriovenosa Iliac aneurysm associated with arteriovenous fistula

    Daniel Mendes Pinto

    2007-09-01

    Full Text Available A ruptura dos aneurismas aorto-ilíacos para a veia ilíaca ou veia cava é uma complicação pouco comum. A hipertensão venosa leva a vários sinais e sintomas, o que dificulta o diagnóstico pré-operatório, tais como edema do membro inferior, dispnéia, hematúria, sinais de insuficiência renal ou cardíaca. Sopro abdominal é a chave do diagnóstico clínico, associado à massa pulsátil e dor abdominal. O reconhecimento da fístula arteriovenosa no pré-operatório é importante para o planejamento cirúrgico. Relatamos um caso de aneurisma da artéria ilíaca comum e interna direita associado a fístula para veia ilíaca comum, cursando, inicialmente, com edema do membro inferior direito e dispnéia, o que levou ao diagnóstico incorreto de trombose venosa profunda.Rupture of aortoiliac aneurysms into the iliac vein or vena cava is an uncommon complication. Many signs and symptoms develop as a result of venous hypertension, which makes preoperative diagnosis difficult, such as leg edema, dyspnea, hematuria, signs of renal or cardiac insufficiency. Abdominal bruit, associated with pulsatile mass and abdominal pain, is the key for clinical diagnosis. Preoperative recognition of arteriovenous fistula is important for surgical planning. We report a case of right internal and common iliac artery aneurysm associated with fistula into the common iliac vein. Initial symptoms were right leg edema and dyspnea, which induced to the incorrect diagnosis of deep vein thrombosis.

  10. Correlation between electrical properties and thermodynamic stability of ACoO3-δ perovskites (A= La, Pr, Nd, Sm, Gd)

    For perovskites with the general formula ACoO3-δ (A = La, Pr, Nd, Sm, and Gd) the influence of the A-site cation on the electrical conductivity, electronic structure, thermodynamic stability, and oxygen stoichiometry was studied. The perovskite oxide powders were produced by a combined citric acid and ethylenediaminetetraacetic acid complexing method. Ceramic specimens sintered at 1100 deg. C in air were single-phase perovskites. With increasing temperature, the electrical conductivity shows three discrete regimes. All compositions show semiconductivity up to a transition temperature of ∼300 deg. C-450 deg. C and then behave like metallic conductors. The activation energies for the semiconductivity, as well as the transition temperatures to the metallic-like conduction, decrease monotonically with increasing pseudocubic lattice parameters, i.e., with increasing ionic radii of the A cation. This behavior correlates with decreasing oxygen nonstoichiometry and increased thermodynamic stability. The highest conductivity and the lowest activation energy of 0.66 eV were found for LaCoO3-δ, which also had the lowest semiconductor-metal transition temperature at 269 deg. C, the lowest oxygen nonstoichiometry of δ= 0.008, and the highest Gibbs free energy change for the decomposition reaction of 42.37 kJ/mol at 850 deg. C. GdCoO3-δ had the highest oxygen nonstoichiometry with δ0.032, a high activation energy of 1.19 eV for the semiconductivity with a high transition temperature at 452 deg. C, and the lowest Gibbs free energy change of 26.54 kJ/mol at 850 deg. C. X-ray absorption spectroscopy data imply an increasing Co low-spin character with decreasing cation radius from La to Gd, while an increase in temperature increases the number of holes or Co 3d bandwidth. This correlates well with the electrical conductivity data.

  11. Desarrollo de una escala de auto-reporte para medición de síntomas maníacos

    Karol Barrios; Jorge Rodríguez-Losada; Ricardo Sánchez

    2014-01-01

    Resumen Antecedentes. No existen instrumentos de auto-reporte en español para medir síntomas de trastorno bipolar. La perspectiva del paciente puede dar información complementaria de utilidad para el diagnóstico y manejo de la enfermedad. Objetivo. Desarrollar una escala de auto-reporte para medir síntomas maníacos, a partir de la escala EMUN. Materiales y métodos. Los ítems de la escala EMUN se transformaron a un lenguaje en primera persona por parte de dos psiquiatras. Esta versión prelimin...

  12. QUINOA (CHENOPODIUM QUINOA WILLD): DIGESTIBILIDADE IN VITRO, DESENVOLVIMENTO E ANÁLISE SENSORIAL DE PREPARAÇÕES DESTINADAS A PACIENTES CELÍACOS

    L. I. A. CASTRO; C. M. V. REAL; I. S. C. PIRES; C. V. PIRES; N. A.V.D. PINTO; Miranda, L. S.; B. C. ROSA; P. A. DIAS

    2008-01-01

    A quinoa (Chenopodium quinoa Willd) é um pseudocereal isento de glúten, oriundo dos Andes, onde tem sido cultivado há milhares de anos. O objetivo deste trabalho foi desenvolver e avaliar sensorialmente algumas preparações contendo quinoa em grãos, flocos e farinha, destinadas ao paciente celíaco, e determinar a digestibilidade in vitro de sua proteína, submetida ou ...

  13. Taponamiento cardíaco debido a perforación de la aurícula derecha por catéter venoso central

    V. Ramos Medina; I. Palomo Gómez; P.J. Aranda Granados; J.L. Palomo Rando; M. Salguero Villadiego

    2014-01-01

    El taponamiento cardíaco es una complicación devastadora de los catéteres venosos centrales. Se debe en general a que la punta del catéter alcanza indebidamente las cavidades cardíacas derechas. Para la correcta identificación en la autopsia por el patólogo forense es importante que a los pacientes fallecidos en los hospitales que van a ser sometidos a autopsia no se les retiren los dispositivos que tengan insertados, e igualmente que no se les retiren en la sala de autopsias hasta que no se ...

  14. Contribuição de decavanadato para os efeitos IN VIVO e IN VITRO de vanadato no músculo cardíaco

    Soares, S. S.

    2007-01-01

    Tese dout., Biologia - Fisiologia Animal, Universidade do Algarve, 2007 No presente estudo aborda-se a contribuição da espécie decamérica de vanadato nos efeitos tóxicos in vivo e in vitro de vanadato. Após administração intravenosa de decavanadato em Sparus aurata, o vanadato decamérico induz respostas nos marcadores de stresse oxidativo do tecido cardíaco distintas das promovidas pelo monovanadato, evidenciando a importância de considerar a contribuição dos diferentes olig...

  15. Renovar novelando: lo apolíneo y lo dionisíaco en Las cerezas del cementerio de Gabriel Miró

    Thion Soriano-Mollá, Dolores

    2010-01-01

    Con Las cerezas del cementerio, Gabriel Miró se enfrenta a un doble reto, renovar la novela por los cauces de la subjetividad, el intimismo y el lirismo así como dar vida literaria a uno de los planteamientos centrales de El nacimiento de la tragedia de Nietzsche, la relación entre lo apolíneo y lo dionisíaco desde un punto de vista vital, estético y ontológico a través de su protagonista, el joven Félix Valdivia, quien encarna el triunfo de Dioniso.

  16. Investigação de lipofuscina em miócitos cardíacos de camundongos após tratamento com oxamniquine

    Maria Luiza Silveira Mello; Carmen S. Bertuzzo

    1984-01-01

    A fluorescencia natural devida à presença de corpos de lipofuscina foi pesquisada em miócitos cardíacos de camundongos adultos jovens tratados com oxamniquine. O objetivo foi buscar uma evidência de indução de envelhecimento celular precoce, com base em dados prévios de acentuação poliploidia, promovida pela droga. Comparando o miocárdio dos camundongos tratados com animais contrôle jovens e velhos, não foi observada a presença de lipofuscina nos seus miócitos. Isto possivelmente se deva a um...

  17. Mecanismo del daño mecánico letal por reoxigenación en miocitos cardíacos

    Ruiz Meana, Marisol

    1998-01-01

    Los miocitos cardíacos sometidos a hipoxia prolongada presentan un gran aumento en la concentración de Ca2+ citosólico. Durante la reoxigenación, la reactivación de la producción energética mitocondrial en presencia de Ca2+ citosólico elevado provoca una activación exagerada de la contractilidad celular que puede llegar a deformar irreversiblemente el citoesqueleto y romper la membrana celular. Este fenómeno, conocido como hipercontractura, es el responsable de la muerte celular que se produ...

  18. Espectro óculo-aurículo-vertebral em pacientes com defeitos cardíacos congênitos

    Rafael Fabiano Machado Rosa

    2010-10-01

    Full Text Available FUNDAMENTO: Há poucos estudos avaliando a frequência do espectro óculo-aurículo-vertebral (EOAV nos pacientes com defeitos cardíacos congênitos (DCC. OBJETIVO: Verificar a frequência do EOAV em uma amostra de pacientes com malformações cardíacas graves. MÉTODOS: Avaliamos uma coorte prospectiva de pacientes com DCC, admitidos em uma unidade de terapia intensiva (UTI cardiopediátrica no Brasil. O diagnóstico de EOAV foi feito com base em dados clínicos, considerando critérios padrões. Os pacientes que preenchiam esses critérios foram submetidos ao cariótipo de alta resolução com bandamento GTG e hibridização fluorescente in situ para a microdeleção 22q11.2. O teste exato de Fisher (P < 0,05 foi usado para as análises estatísticas. RESULTADOS: Durante o período de avaliação, 330 pacientes foram hospitalizados pela primeira vez na UTI, mas trinta deles não participaram deste estudo. Dos 300 pacientes que constituíram a amostragem final, o EOAV foi verificado em três casos (1%. Todos apresentaram estudos citogenéticos normais. CONCLUSÃO: O EOAV parece ser uma condição frequente em pacientes com DCC. Contudo, não podemos excluir a possibilidade de que a frequência de EOAV encontrada em nosso estudo possa ter sido subestimada devido à baixa taxa de detecção pré-natal de DCC e ao acesso limitado dos pacientes ao tratamento médico apropriado em nosso meio. Estudos prospectivos futuros com critérios clínicos bem definidos e pacientes com defeitos leves e graves serão importantes para avaliar o papel do EOAV na população em geral de indivíduos com malformações cardíacas.

  19. Characterization of transcriptional profiles of MA-ACS1 and MA-ACO1 genes in response to ethylene, auxin, wounding, cold and different photoperiods during ripening in banana fruit.

    Choudhury, Swarup Roy; Roy, Sujit; Sengupta, Dibyendu N

    2008-12-01

    The ripening-specific genes MA-ACS1 (Musa acuminata ACC synthase1) and MA-ACO1 (M. acuminata ACC oxidase 1) are regulated in response to a wide variety of factors. Here, we have studied the differential transcript accumulation pattern and protein levels of MA-ACS1 and MA-ACO1 genes in response to ethylene, auxin, wounding and low temperature in preclimacteric banana fruit. We have shown that exogenous application of ethylene and auxin induced the expression of MA-ACS1, while MA-ACO1 showed marginal expression following ethylene treatment in preclimacteric stage. Auxin did not induce MA-ACO1 expression. Thus, auxin-treated banana fruits showed lower ethylene production rate as compared to ethylene-treated fruits. Conversely, wounding and cold treatment down-regulated the expression of both the genes and thus inhibited ethylene production. Furthermore, we have detected a GCC-box putative ethylene-responsive element (ERE)- and an auxin-responsive element (ARE)-specific DNA-binding activity in the banana pulp and studied the ethylene and auxin responsive characteristics of the GCC-box and ARE (TGTCTC) containing synthetic promoter fragments. In addition, we have detected an enhanced ethylene production rate and expression level of MA-ACS1 and MA-ACO1 genes along with a strong GCC-box-specific DNA-binding activity following exposure to constant dark period for 8d at the preclimacteric stage. Together, our study provides interesting information about the regulation of expression of MA-ACS1 and MA-ACO1 genes in response to various factors during ripening in banana fruit, which may have physiological relevance concerning ethylene biosynthesis during post-harvest conditions. PMID:18554749

  20. Estudio y diseño de un sistema de monitorización del ritmo cardíaco basado en un PSoC y un dispositivo móvil inteligente

    Hernández Gómez, Elías

    2015-01-01

    Este trabajo tiene como objetivo diseñar un sistema que permita monitorizar el ritmo cardíaco, apoyándose en un circuito diseñado especialmente para medir y acondicionar dicha señal con un dispositivo de tipo PSoC, que también será usado para la recopilación de datos, y una aplicación de Android para monitorizarlos. Por tanto, se plantean los siguientes objetivos para realizar el sistema propuesto:  -Estudiar el sensor necesario para medir el pulso cardíaco, seleccionando los ...

  1. Análisis de la calidad del registro de paro cardíaco en casos de responsabilidad médico legal en médicos generales, 1999-2007

    Barragán, Gabriel; Navarro Vargas, José Ricardo; Marulanda, Nathalie; Eslava Schmalbach, Javier Hernando

    2010-01-01

    Antecedentes. El registro del paro cardíaco es una actividad que se debe acompañar en la reanimación cerebro cardio pulmonar. En Colombia no existe un formato de registro oficial de paro cardiorrespiratorio, lo que dificulta la investigación en reanimación y la conducción de los procesos de responsabilidad médica que se deriven de esta atención. Objetivo. Analizar la calidad del registro de paro cardíaco en casos de responsabilidad médico legal iniciada a médicos generales que tuvieron as...

  2. Dynamics and performance of the free electron laser at Super-Aco with a harmonic RF cavity set on 500 MHz

    This work is dedicated to the development of the potentialities of the free electron laser that has been installed on the storage ring Super-Aco at Orsay university. We have studied the dynamics of the electron beam inside a harmonic RF cavity set on 500 MHz. The impact of the geometric characteristics of the optical cavity on the transverse overlapping between laser radiation and the electron beam has been studied in details. An important part of the work has been the assessment of the optical characterization of the dielectric multi-layer mirrors of the cavity. For that purpose a complete system has been designed to assess the changes in optical properties of mirrors during laser operation. Another important part of this work was the study of the interaction process between laser radiation and the electron bunch leading to saturation. This interaction process has been simulated through a new model and some predictions given by this model have been successfully confronted to experimental data. The installation of the harmonic RF cavity has led to a significant increase of the laser radiation gain and the value of the mean power of the laser radiation has reached 300 mW. An interesting application of this technique is the generation of high energy gamma photons through Compton backscattering. A collimated 35 MeV-energy photon beam has been produced at Super-Aco with a rate of 5.106 photons per second. (A.C.)

  3. Advance Payment ACO Model

    U.S. Department of Health & Human Services — The Advance Payment Model is designed for physician-based and rural providers who have come together voluntarily to give coordinated high quality care to the...

  4. ACO - Ant Colony Optimization

    Žumer, Viljem; Brest, Janez; Pešl, Ivan

    2015-01-01

    Ant colony optimization is a relatively new approach to solving NP-Hard problems. It is based on the behavior of real ants, which always find the shortest path between their nest and a food source. Such behavior can be transferred into the discrcte world, were real ants are replaced by simple agents. Such simple agents are placed into the environment where different combinatorial problems can be solved In this paper we describe an artificial ant colony capable of solving the travelling salesm...

  5. Characterization and expression profiles of MaACS and MaACO genes from mulberry (Morus alba L.)%桑树MaACS和MaACO基因的鉴定和表达模式研究

    Chang-ying LIU; Shu-mei HAN; Cheng LU; Mao-de YU; Rui-hua LÜ; Jun LI; Ai-chun ZHAO; Xi-ling WANG; Umuhoza DIANE; Xiao-hong WANG; Chuan-hong WANG; Ya-sheng YU

    2014-01-01

    1-Aminocyclopropane-1-carboxylic acid synthase (ACS) and 1-aminocyclopropane-1-carboxylic acid oxidase (ACO) are encoded by multigene families and are involved in fruit ripening by catalyzing the production of ethylene throughout the development of fruit. However, there are no reports on ACS or ACO genes in mulberry, partly because of the limited molecular research background. In this study, we have obtained five ACS gene sequences and two ACO gene sequences from Morus Genome Database. Sequence alignment and phylogenetic analysis of MaACO1 and MaACO2 showed that their amino acids are conserved compared with ACO proteins from other species. MaACS1 and MaACS2 are type I, MaACS3 and MaACS4 are type II, and MaACS5 is type III, with different C-terminal se-quences. Quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) expression analysis showed that the transcripts of MaACS genes were strongly expressed in fruit, and more weakly in other tissues. The expression of MaACO1 and MaACO2 showed different patterns in various mulberry tissues. MaACS and MaACO genes demon-strated two patterns throughout the development of mulberry fruit, and both of them were strongly up-regulated by abscisic acid (ABA) and ethephon.%研究目的:分离和鉴定桑树中参与乙烯生物合成的酶的编码基因MaACS 和MaACO,研究其表达模式。创新要点:基于最新公布的桑树基因组数据库数据,获得5个MaACS 基因和2个MaACO 基因,对其进行了生物信息分析,同时鉴定了其在不同桑树组织中、不同发育时期桑椹中和不同激素作用下的表达模式。研究方法:通过生物信息学方法筛选和鉴定基因,利用荧光定量逆转录聚合酶链式反应(qRT-PCR)分析基因的表达量。重要结论:MaACS 和MaACO 基因在根、茎、叶等不同组织中呈现出不同的表达模式,在桑椹发育过程中呈现出两种表达模式,其表达量被脱落酸和乙烯利上调。

  6. Consistent Evaluation of ACOS-GOSAT, BESD-SCIAMACHY, CarbonTracker, and MACC Through Comparisons to TCCON

    Kulawik, Susan; Wunch, Debra; O’Dell, Christopher; Frankenberg, Christian; Reuter, Maximilian; Chevallier, Frederic; Oda, Tomohiro; Sherlock, Vanessa; Buchwitz, Michael; Osterman, Greg; Miller, Charles E.; Iraci, Laura T.; Wolf, Joyce

    2016-01-01

    Consistent validation of satellite CO2 estimates is a prerequisite for using multiple satellite CO2 measurements for joint flux inversion, and for establishing an accurate long-term atmospheric CO2 data record. Harmonizing satellite CO2 measurements is particularly important since the differences in instruments, observing geometries, sampling strategies, etc. imbue different measurement characteristics in the various satellite CO2 data products. We focus on validating model and satellite observation attributes that impact flux estimates and CO2 assimilation, including accurate error estimates, correlated and random errors, overall biases, biases by season and latitude, the impact of coincidence criteria, validation of seasonal cycle phase and amplitude, yearly growth, and daily variability. We evaluate dry-air mole fraction (X(sub CO2)) for Greenhouse gases Observing SATellite (GOSAT) (Atmospheric CO2 Observations from Space, ACOS b3.5) and SCanning Imaging Absorption spectroMeter for Atmospheric CHartographY (SCIAMACHY) (Bremen Optimal Estimation DOAS, BESD v2.00.08) as well as the CarbonTracker (CT2013b) simulated CO2 mole fraction fields and the Monitoring Atmospheric Composition and Climate (MACC) CO2 inversion system (v13.1) and compare these to Total Carbon Column Observing Network (TCCON) observations (GGG2012/2014). We find standard deviations of 0.9, 0.9, 1.7, and 2.1 parts per million vs. TCCON for CT2013b, MACC, GOSAT, and SCIAMACHY, respectively, with the single observation errors 1.9 and 0.9 times the predicted errors for GOSAT and SCIAMACHY, respectively. We quantify how satellite error drops with data averaging by interpreting according to (error(sup 2) equals a(sup 2) plus b(sup 2) divided by n (with n being the number of observations averaged, a the systematic (correlated) errors, and b the random (uncorrelated) errors). a and b are estimated by satellites, coincidence criteria, and hemisphere. Biases at individual stations have year

  7. Consistent evaluation of ACOS-GOSAT, BESD-SCIAMACHY, CarbonTracker, and MACC through comparisons to TCCON

    Kulawik, Susan; Wunch, Debra; O'Dell, Christopher; Frankenberg, Christian; Reuter, Maximilian; Oda, Tomohiro; Chevallier, Frederic; Sherlock, Vanessa; Buchwitz, Michael; Osterman, Greg; Miller, Charles E.; Wennberg, Paul O.; Griffith, David; Morino, Isamu; Dubey, Manvendra K.; Deutscher, Nicholas M.; Notholt, Justus; Hase, Frank; Warneke, Thorsten; Sussmann, Ralf; Robinson, John; Strong, Kimberly; Schneider, Matthias; De Mazière, Martine; Shiomi, Kei; Feist, Dietrich G.; Iraci, Laura T.; Wolf, Joyce

    2016-02-01

    Consistent validation of satellite CO2 estimates is a prerequisite for using multiple satellite CO2 measurements for joint flux inversion, and for establishing an accurate long-term atmospheric CO2 data record. Harmonizing satellite CO2 measurements is particularly important since the differences in instruments, observing geometries, sampling strategies, etc. imbue different measurement characteristics in the various satellite CO2 data products. We focus on validating model and satellite observation attributes that impact flux estimates and CO2 assimilation, including accurate error estimates, correlated and random errors, overall biases, biases by season and latitude, the impact of coincidence criteria, validation of seasonal cycle phase and amplitude, yearly growth, and daily variability. We evaluate dry-air mole fraction (XCO2) for Greenhouse gases Observing SATellite (GOSAT) (Atmospheric CO2 Observations from Space, ACOS b3.5) and SCanning Imaging Absorption spectroMeter for Atmospheric CHartographY (SCIAMACHY) (Bremen Optimal Estimation DOAS, BESD v2.00.08) as well as the CarbonTracker (CT2013b) simulated CO2 mole fraction fields and the Monitoring Atmospheric Composition and Climate (MACC) CO2 inversion system (v13.1) and compare these to Total Carbon Column Observing Network (TCCON) observations (GGG2012/2014). We find standard deviations of 0.9, 0.9, 1.7, and 2.1 ppm vs. TCCON for CT2013b, MACC, GOSAT, and SCIAMACHY, respectively, with the single observation errors 1.9 and 0.9 times the predicted errors for GOSAT and SCIAMACHY, respectively. We quantify how satellite error drops with data averaging by interpreting according to error2 = a2 + b2/n (with n being the number of observations averaged, a the systematic (correlated) errors, and b the random (uncorrelated) errors). a and b are estimated by satellites, coincidence criteria, and hemisphere. Biases at individual stations have year-to-year variability of ˜ 0.3 ppm, with biases larger than the TCCON

  8. Avaliação do sopro cardíaco na infância Assessment of heart murmurs in childhood

    Maria Elisabeth B.A. Kobinger

    2003-06-01

    Full Text Available OBJETIVO: discutir a avaliação clínica e laboratorial do sopro cardíaco, considerando sua alta freqüência no atendimento ambulatorial do pediatra geral. FONTE DE DADOS: revisão baseada na análise crítica da literatura atual e consulta a compêndios de cardiologia pediátrica e pediatria contendo informações básicas sobre o tema. SÍNTESE DOS DADOS: os principais destaques do artigo referem-se à importância da anamnese e exame físico do sistema cardiovascular, essenciais para o pediatra geral diagnosticar o sopro cardíaco inocente, e identificar situações que indiquem a ocorrência de cardiopatias congênitas, ou adquiridas, e a necessidade de encaminhamento ao especialista. CONCLUSÕES: o pediatra geral é geralmente o primeiro médico a detectar um sopro cardíaco e deve estar apto a reconhecer o sopro inocente, assim como a suspeitar precocemente de doenças cardiovasculares.OBJECTIVE: to discuss clinical and laboratorial evaluation of heart murmurs in children, an important problem faced by pediatricians in their practice. SOURCES OF DATA: this review was based on a critical analysis of the current literature, as well as pediatrics and pediatric cardiology textbooks, which were found to be an important source of information on the subject. SUMMARY OS THE FINDINGS: it is important for pediatricians to know how to obtain precise information regarding the patient's medical history and to perform extensive physical examination of a child with heart murmur. The diagnosis of innocent heart murmur is essentially clinical and it can help the pediatrician to identify situations which are associated with cardiovascular diseases. CONCLUSIONS: in our series, short-term video-EEG monitoring established a reliable diagnosis in most patients due to correlation between clinical and EEG data. This procedure was well tolerated by children, including infants and those with psychiatric disorders.

  9. Transplante experimental cardíaco heterotópico e cutâneo em camundongos Experimental heterotopic cardiac and cutaneous transplantation in mice

    Patrícia Sestrheim

    2005-06-01

    Full Text Available OBJETIVO: Estudo experimental com o objetivo de desenvolver e avaliar a viabilidade das técnicas de transplante experimental cardíaco heterotópico abdominal vascularizado e cutâneo em camundongos, criando um instrumento para investigação da eficácia de soluções de preservação, novas drogas imunossupressoras, agentes biológicos, terapia gênica e indução de tolerância imunológica. MÉTODO: Para este estudo, as técnicas utilizadas foram descritas previamente por Corry et al. e Billingham et al. RESULTADOS: O tempo cirúrgico total para a realização dos transplantes cardíacos (n=20 foi, em média, 60,3±6,3 minutos e para os transplantes cutâneos (n=20, 17,75±0,71 minutos. A média de sobrevida dos aloenxertos cutâneos (n=34 e cardíacos (n=24 foi, respectivamente, 7 e 11 dias, enquanto que os isoenxertos sobreviveram por mais de 100 dias. CONCLUSÕES: Ambas as técnicas se caracterizaram pela fácil reprodutibilidade dos modelos experimentais. As diferenças entre as técnicas não se limitaram às peculiaridades metodológicas ou ao tempo de sobrevida e vascularização, mas principalmente à sua imunogenicidade e suscetibilidade à rejeição.OBJECTIVE: This is an experimental study which aims at developing and evaluating the feasibility of experimental techniques of vascularized and cutaneous abdominal heterotopic heart transplant in mice, creating an instrument of investigation for the effectiveness of prservation solutions, new immunosuppressive drugs, biological agents, genetic therapy and induction of immunological tolerance. METHOD: The techniques used in this work were previously described by Corry et al. and Billingham et al. RESULTS: The total surgical time to perform the cardiac transplants (n=20 was on average 60.3+6.3 minutes and the time of cutaneous transplants (n= 20 17.75+0.71 minutes. The average survival of the cutaneous allografts (n=34 and cardiac (n=24 allografts was 7 and 11 days, respectively, while

  10. Tamponamento cardíaco tardio traumático: análise de cinco casos Traumatic late cardiac tamponade: analysis of five cases

    FERNANDO LUIZ WESTPHAL

    2000-09-01

    Full Text Available São analisados cinco casos de tamponamento cardíaco tardio traumático. Os pacientes eram masculinos, idade média de 26,2 anos, vítimas de ferimento por arma branca em região precordial, área de Ziedler, sendo admitidos em centro de referência para trauma. Foram classificados pelo índice fisiológico de Ivatury para trauma cardíaco e inicialmente tratados por pleurotomia intercostal e reposição volêmica, com estabilização do quadro hemodinâmico e respiratório. Os pacientes foram readmitidos após intervalo de oito a 24 dias (mediana de 20 dias, agora no serviço de cirurgia torácica de um hospital de referência terciária, com sinais de tamponamento cardíaco. Os exames diagnósticos confirmaram derrame pericárdico com espessamento pericárdico associado a encarceramento de base pulmonar esquerdo em quatro casos, os quais foram abordados por toracotomia póstero-lateral, com realização de pericardiectomia parcial e descorticação pulmonar. Um paciente evoluiu com pericardite purulenta, comprovada por exames complementares, e foi submetido à drenagem pericárdica subxifóidea. Ocorreu arritmia pós-operatória em um paciente; os demais evoluíram sem complicações pós-operatórias ou recidiva do tamponamento.Five traumatic late cardiac tamponade cases were analyzed. All patients were male, mean age was 26.2, victims of thoracic penetrating stabbing wound in the precordial region, Ziedler area, admitted to a trauma reference center. They were classified by the Ivatury physiological index for cardiac trauma. The first treatment approach was intercostal pleurectomy and volemic resuscitation followed by hemodynamic and respiratory recovery. Patients with cardiac tamponade symptoms were re-admitted within an interval from eight to twenty four days (mean 20 days in a thoracic surgery service of a tertiary reference hospital. Diagnostic exams confirmed thickening and pericardial effusion associated with a left pulmonary base

  11. Bioimpedância transtorácica comparada à ressonância magnética na avaliação do débito cardíaco

    Humberto Villacorta Junior

    2012-12-01

    Full Text Available FUNDAMENTO: A ressonância magnética cardíaca é considerada o método padrão-ouro para o cálculo de volumes cardíacos. A bioimpedância transtorácica cardíaca avalia o débito cardíaco. Não há trabalhos que validem essa medida comparada à ressonância. OBJETIVO: Avaliar o desempenho da bioimpedância transtorácica cardíaca no cálculo do débito cardíaco, índice cardíaco e volume sistólico, utilizando a ressonância como padrão-ouro. MÉTODOS: Avaliados 31 pacientes, com média de idade de 56,7 ± 18 anos, sendo 18 (58% do sexo masculino. Foram excluídos os pacientes cuja indicação para a ressonância magnética cardíaca incluía avaliação sob estresse farmacológico. A correlação entre os métodos foi avaliada pelo coeficiente de Pearson, e a dispersão das diferenças absolutas em relação à média foi demonstrada pelo método de Bland-Altman. A concordância entre os métodos foi realizada pelo coeficiente de correlação intraclasses. RESULTADOS: A média do débito cardíaco pela bioimpedância transtorácica cardíaca e pela ressonância foi, respectivamente, 5,16 ± 0,9 e 5,13 ± 0,9 L/min. Observou-se boa correlação entre os métodos para o débito cardíaco (r = 0,79; p = 0,0001, índice cardíaco (r = 0,74; p = 0,0001 e volume sistólico (r = 0,88; p = 0,0001. A avaliação pelo gráfico de Bland-Altman mostrou pequena dispersão das diferenças em relação à média, com baixa amplitude dos intervalos de concordância. Houve boa concordância entre os dois métodos quando avaliados pelo coeficiente de correlação intraclasses, com coeficientes para débito cardíaco, índice cardíaco e volume sistólico de 0,78, 0,73 e 0,88, respectivamente (p < 0,0001 para todas as comparações. CONCLUSÃO: A bioimpedância transtorácica cardíaca mostrou-se acurada no cálculo do débito cardíaco quando comparada à ressonância magnética cardíaca.

  12. Efecto de la incorporación de fibras dietéticas en la calidad de panes para celíacos

    Díaz Malmierca, Álvaro

    2013-01-01

    La investigación en la elaboración de panes sin gluten está muy avanzada, siendo el déficit en micronutrientes de estos productos uno de los problemas sobre el que se está centrando la investigación. Uno de los nutrientes más deficitarios, y que más problemas causa sobre la salud de los pacientes celíacos es la fibra dietética. En este estudio se ha investigado el efecto que produce la adición de un 10% de diferentes fibras sobre las características de los panes, la influencia ...

  13. Taponamiento cardíaco debido a perforación de la aurícula derecha por catéter venoso central

    V. Ramos Medina

    2014-09-01

    Full Text Available El taponamiento cardíaco es una complicación devastadora de los catéteres venosos centrales. Se debe en general a que la punta del catéter alcanza indebidamente las cavidades cardíacas derechas. Para la correcta identificación en la autopsia por el patólogo forense es importante que a los pacientes fallecidos en los hospitales que van a ser sometidos a autopsia no se les retiren los dispositivos que tengan insertados, e igualmente que no se les retiren en la sala de autopsias hasta que no se haya comprobado su correcta inserción. Se presenta un caso estudiado por nosotros y se analizan otros factores de riesgo de dicha complicación.

  14. Confección de diagramas termodinámicos asociados a la mixtura amoníaco-agua en la fase líquido-vapor

    Napoleão, Diovana Aparecida dos Santos; Silveira, Jose Luz; Reto, Alonso Bernabé Aguirre

    2006-01-01

    El objetivo de este trabajo es determinar la entalpía y la entropía relacionadas a un sistema de refrigeración por absorción, empleando mixturas de amoníaco y agua. El conocimiento de la termodinámica de mezclas, así como la utilización de los diagramas de entalpía-concentración y entropía-concentración son fundamentales para comprender el funcionamiento de los sistemas de refrigeración por absorción. Para proyectos industriales que signifiquen análisis energéticos y exergéticos, si...

  15. O carvedilol no tecido conjuntivo cardíaco de ratos durante o desenvolvimento da hipertrofia miocárdica concêntrica

    Leomil Neto Moacir; Pascoal Lívia Aparecida D'Avila Bitencourt; Balieiro Júlio César Carvalho; Larsson Maria Helena Matiko Akao; Bombonato Pedro Primo; Benedicto Hildebrando Gomes; Elton Lílian Barreto

    2006-01-01

    A estimulação catecolaminérgica precoce e excessiva do coração, que ocorre na insuficiência cardíaca congestiva, acentua a sobrecarga de pressão e o volume nos ventrículos, agravando, conseqüentemente, a isquemia miocárdica, causando morte de miócitos com deposição de tecido conjuntivo e progressiva redução do débito cardíaco. O carvedilol, um b e alfa1-bloqueador não cardio-seletivo, vem sendo associado a melhorias na função miocárdica e à regressão da hipertrofia ventricular esquerda. O obj...

  16. Un sistema presión-volumen para la medición de propiedades mecánicas de vasos cardíacos menores

    Javier Navarro Rueda

    2013-04-01

    Full Text Available Las propiedades mecánicas de vasos cardíacos menores (VM son poco estudiadas. El sistema Presión-Volumen (PV propuesto, desarrollado para evaluar comportamientos esfuerzo-deformación (σ-ε de VM, permite variar controladamente la presión interna y simular alteraciones geométricas al tubo. Se obtuvieron imágenes de las geometrías para cada valor de presión interna. Asumiendo el tubo en equilibrio, con pared elástica y presiones conocidas, se determinaron esfuerzo y deformación circunferenciales. Se obtuvieron curvas σ-ε, validadas con ensayos de tensión uniaxial (TU. Aunque se esperaban comportamientos diferentes, los datos experimentales son consistentes frente a resultados TU, con diferencias entre 5.68 y 12.60 %.

  17. Perfil dos pacientes na Lista Única de Espera para transplante cardíaco no estado do Ceará Perfil de los pacientes en la lista única de espera para transplante cardíaco en el estado de Ceará Profile of patients in the Unified Waiting List for heart transplantation in state of Ceará

    Francisca Elisângela Teixeira Lima

    2010-07-01

    Full Text Available FUNDAMENTO: Os transplantes de órgãos têm aumentado consideravelmente nos últimos anos em razão da evolução tecnológica e da sensibilização da sociedade para doação de órgãos. OBJETIVO: Descrever as características dos pacientes da Lista Única de Espera para transplante cardíaco; identificar as principais cardiopatias; e verificar o tempo médio de permanência do paciente na Lista até a realização da cirurgia. MÉTODOS: Trata-se de um estudo descritivo, documental e retrospectivo, com abordagem quantitativa, desenvolvido na Central de Transplante do Estado do Ceará, com 156 pacientes incluídos na Lista Única de Espera do ano de 1999 a 2006. Os dados foram organizados em figuras. RESULTADOS: Foram encontrados: 81% do sexo masculino; 22,4% adultos jovens (20 a 40 anos e 56,4% adultos de meia-idade (40 a 64 anos, com uma média de 36 anos; 79% procedentes de Fortaleza-CE; 91% tinham miocardiopatia como causa do transplante cardíaco. Dentre esses pacientes 102 (69% foram transplantados; 37 (25% evoluíram para óbito antes do transplante e 8 (6% foram excluídos por melhora ou piora do quadro clínico. CONCLUSÃO: Os pacientes da Lista Única de Espera para transplante cardíaco no Estado do Ceará, no período de 1999 a 2006, eram do sexo masculino (80%, com faixa etária variando de 1 a 71 anos, com predomínio da miocardiopatia dilatada (53,4%, e o tempo médio de espera foi de 136 dias até o dia do transplante cardíaco.FUNDAMENTO: Los transplantes de órganos han aumentado considerablemente en los últimos años, en razón de la evolución tecnológica y de la sensibilización de la sociedad para la donación de órganos. OBJETIVO: Describir las características de los pacientes de la Lista Única de Espera para transplante cardíaco; identificar las principales cardiopatías; y verificar el tiempo medio de permanencia del paciente en la Lista hasta la realización de la cirugía. MÉTODOS: Se trata de un estudio

  18. Qualidade de vida de pacientes submetidos ao transplante cardíaco: aplicação da escala Whoqol-Bref Calidad de vida de pacientes sometidos a transplante cardíaco: aplicación de la escala Whoqol-Bref Quality of life of patients that had a heart transplant: application of Whoqol-Bref scale

    Maria Isis Freire de Aguiar

    2011-01-01

    Full Text Available FUNDAMENTO: O sucesso do transplante cardíaco significa garantir a sobrevida dos pacientes com cardiopatia e permitir-lhes desenvolver suas atividades diárias. O transplante cardíaco apresenta-se como a primeira opção de tratamento na falência cardíaca, representando um aumento de sobrevida e qualidade de vida dos transplantados. OBJETIVO: Avaliar a qualidade de vida de pacientes submetidos ao transplante cardíaco através da aplicação de uma escala padronizada (Whoqol-Bref. MÉTODOS: Estudo exploratório descritivo de abordagem quantitativa, realizado com 55 pacientes submetidos ao transplante cardíaco, em um período entre o terceiro e o 103º mês, que realizam acompanhamento na Unidade de Transplante e Insuficiência Cardíaca em um Hospital de Referência em Cardiologia na cidade de Fortaleza, CE. Os dados foram coletados no período de fevereiro a abril de 2009, por meio da aplicação de um questionário padronizado pela Organização Mundial da Saúde e utilização de dados constantes nos prontuários. RESULTADOS: Com relação ao domínio físico, 62,8% e 58,3% dos pacientes, dos sexos masculino e feminino, respectivamente, estão satisfeitos. No domínio psicológico, dentre pacientes do sexo masculino, 65,1% apresentam satisfação quanto à qualidade de vida e, no sexo feminino, 58,3% encontram-se satisfeitas. No domínio das relações sociais, observou-se que, no sexo masculino, 53,5% estão muito satisfeitos, e apresentou-se um nível de satisfação de 100% no sexo feminino. No domínio do meio ambiente, 65,1% do sexo masculino encontram-se satisfeitos, e no sexo feminino, 83,3% estão satisfeitas. CONCLUSÃO: O transplante cardíaco teve bastante influência na qualidade de vida dos pacientes transplantados, pois os resultados mostram-se estatisticamente significantes no pós-transplante.FUNDAMENTO: El éxito del transplante cardíaco significa garantizar la sobrevida de los pacientes con cardiopatía y permitirles

  19. Hemorrhage in cerebral metastasis from angiosarcoma of the heart: case report Hemorragia em metástase cerebral de angiossarcoma cardíaco: relato de caso

    Pasquale Gallo

    2001-09-01

    Full Text Available The purpose of this article is to describe the clinical and pathological features of metastatic angiosarcoma in the central nervous system. Only a few cases of cerebral metastasis from angiosarcoma of the heart have been recorded in the literature; particulary related to intracerebral hemorrhage. A case of secondary cerebral angiosarcoma of the heart in a 33 years old man is presented. The initial symptoms were headache, vomiting, lethargy and aphasia. There was a mass in the left temporal lobe with hemorrhage and edema on the computerized tomography (CT. After 24 hours the neurological status worsened and another CT scan showed rebleeding on the tumor area. He underwent an emergency craniotomy but died two days after. Considering the longer survival of sarcoma patients with new modalities of treatment, the incidence of brain metastasis may increase, demanding a bether preventive and more aggressive approach. Besides, due to the hemorrhagic nature of such lesions, we suggest the imediate surgery to prevent a fast and lethal evolution because rebleeding.O propósito deste artigo é descrever os achados clínicos e patológicos das metástases de angiossarcoma no sistema nervoso central. Apenas poucos casos de metástases cerebrais de angiossarcoma cardíaco foram relatados na literatura, menos ainda relacionados a hemorragia intracerebral. Relatamos o caso de um tumor cerebral secundário a angiossarcoma cardíaco em um paciente masculino de 33 anos. Os sintomas iniciais foram: cefaléia, vômitos, letargia e afasia. A tomografia computadorizada mostrou massa no lobo temporal esquerdo associada a hemorragia e edema. Após 24 horas houve piora do estado neurológico e nova tomografia demonstrou ressangramento no leito tumoral. Foi submetido a uma craniotomia de urgência mas faleceu dois dias após. Considerando a longa sobrevida dos pacientes com sarcoma devido às novas modalidades terapêuticas, poderá aumentar a incidência de met

  20. Expression of ACO1, ERS1 and ERF1 genes in harvested bananas in relation to heat-induced defense against Colletotrichum musae.

    Zhu, Xiangfei; Wang, Aiping; Zhu, Shijiang; Zhang, Lubin

    2011-09-15

    The aim of this study was to investigate the connection between heat-induced ethylene signal changes and enhanced disease resistance. Heat enhanced ripening and elevated MaACO1 expression in naturally ripened bananas (NRB), while it delayed ripening and reduced MaACO1expression in the ethephon-treated bananas (ETB). However, in both cases, heat reduced lesion sizes infected by Colletotrichum musae. This indicates that heat-induced disease resistance in bananas was independent of ripening rate. The expression of MaERS1 gene was inhibited by heat treatment in both NRB and ETB, implying that heat as a physical signal could be sensed by banana fruits through the inhibition of ethylene receptor gene expression. The intensity of MaERF1 transcript signals was elevated in heated bananas, suggesting that the enhanced accumulation of MaERF1 transcript following heat treatment could play an important role in activation of the defense system. In ETB, inhibition of JA biosynthesis by application of IBU down-regulated the expression of MaERF and significantly weakened disease resistance, suggesting involvement of endogenous JA in induction of the gene expression, which was reconfirmed by the fact that exposure to exogenous MeJA following the combination of heat plus IBU treatment restored part of the gene expression. On the other hand, in NRB, application of IBU elevated level of MaERF1 expression at 24h and enhanced disease resistance, suggesting that, when banana was not exposed to ethephon, the expression of MaERF1 gene was not JA dependent, which was verified by the fact that MeJA application did not enhance MaERF1 gene expression. In conclusion, heat-induced disease resistance in harvested bananas could involve down-regulation of MaERS1 expression and up-regulation of MaERF1 expression and JA pathway could be involved in heat activation of the defense system in bananas exposed to ethephon. PMID:21511361

  1. Utilidade do Ultrassom intracardíaco no isolamento de veias pulmonares usando cateter-balão a laser Utilidad del ultrasonido intracardíaco en el aislamiento de venas pulmonares usando catéter-balón láser Utility of intracardiac ultrasound imaging to guide pulmonary vein ablation using laser balloon catheter

    Luiz Leite; Wilber Su; Johnson, Susan B.; Mark Milton; Benhur Henz; Alvaro Sarabanda; Santos, Simone N.; Packer, Douglas L.

    2009-01-01

    FUNDAMENTO: O isolamento das veias pulmonares (IVP) tem sido usado como endpoint para a ablação da fibrilação atrial (FA) com cateter balão. OBJETIVO: Determinar a utilidade do ultrassom intracardíaco (USIC) para guiar o IVP, usando cateter balão a laser. MÉTODOS: 59 VP foram ablacionadas em 27 cães. Imagens de Doppler foram usadas para identificar os vazamentos do fluxo sanguíneo entre a VP e o balão. Após cada liberação de energia, o cateter de mapeamento circular foi reposicionado para ver...

  2. Desarrollo de una escala de auto-reporte para medición de síntomas maníacos

    Karol Barrios

    2013-09-01

    Full Text Available Resumen Antecedentes. No existen instrumentos de auto-reporte en español para medir síntomas de trastorno bipolar. La perspectiva del paciente puede dar información complementaria de utilidad para el diagnóstico y manejo de la enfermedad. Objetivo. Desarrollar una escala de auto-reporte para medir síntomas maníacos, a partir de la escala EMUN. Materiales y métodos. Los ítems de la escala EMUN se transformaron a un lenguaje en primera persona por parte de dos psiquiatras. Esta versión preliminar en primera persona fue analizada en un estudio piloto y ajustada de acuerdo con los resultados de la evaluación. Se realizó un segundo estudio piloto con 20 pacientes con enfermedad bipolar, aplicando la versión ajustada. Resultados. Se generó una escala con 26 ítems que incorporan síntomas del episodio mixto. La escala mide tres dimensiones de importancia clínica en salud mental: frecuencia, intensidad y grado de desadaptación producido por los síntomas. Conclusión. El instrumento desarrollado puede ser de utilidad en áreas de investigación y en escenarios clínicos para intervenciones psicoeducativas y seguimiento del paciente.

  3. The Norma cluster (ACO3627) -- III. The Distance and Peculiar Velocity via the Near-Infrared Ks-band Fundamental Plane

    Mutabazi, T; Woudt, P A; Lucey, J R; Jarrett, T H; Bilicki, M; Schroder, A C; Moore, S A W

    2014-01-01

    While Norma (ACO3627) is the richest cluster in the Great Attractor (GA) region, its role in the local dynamics is poorly understood. The Norma cluster has a mean redshift (z_CMB) of 0.0165 and has been proposed as the "core" of the GA. We have used the Ks-band Fundamental Plane (FP) to measure Norma cluster's distance with respect to the Coma cluster. We report FP photometry parameters (effective radii and surface brightnesses), derived from ESO NTT SOFI images, and velocity dispersions, from AAT 2dF spectroscopy, for 31 early-type galaxies in the cluster. For the Coma cluster we use 2MASS images and SDSS velocity dispersion measurements for 121 early-type galaxies to generate the calibrating FP dataset. For the combined Norma-Coma sample we measure FP coefficients of a=1.465+/-0.059 and b=0.326+/-0.020. We find an rms scatter, in log(sigma) of 0.08 dex which corresponds to a distance uncertainty of 28% per galaxy. The zero point offset between Norma's and Coma's FPs is 0.154+\\-0.014 dex. Assuming that the C...

  4. A Transition from Localized to Strongly Correlated Electron Behavior and Mixed Valence Driven by Physical or Chemical Pressure in ACo2As2 (A = Eu and Ca)

    Tan, Xiaoyan; Fabbris, Gilberto; Haskel, Daniel; Yaroslavtsev, Alexander A.; Cao, H.; Thompson, Corey M.; Kovnir, Kirill; Menushenkov, Alexey P.; Chernikov, Roman V.; Garlea, V. Ovidiu; Shatruk, Michael

    2016-03-02

    We demonstrate that the action of physical pressure, chemical compression, or aliovalent substitution in ACo(2)As(2) (A = Eu and Ca) has a general consequence of causing these antiferromagnetic materials to become ferromagnets. In all cases, the mixed valence triggered at the electropositive A site results in the increase of the Co 3d density of states at the Fermi level. Remarkably, the dramatic alteration of magnetic behavior results from the very minor (<0.15 eleetron) change in the population of the 3d orbitals. The mixed valence state of En observed in the high-pressure (HP) form of EuCo2As2 exhibits a remarkable stability, achieving the average oxidation state of +2.25 at 12.6 GPa. In the case of CaCo2As2, substituting even 10% of Eu or La into the Ca site causes ferromagnetic ordering of Co moments. Similar to HP-EuCo2As2, the itinerant 3d ferromagnetism emerges from electronic doping into the Co layer because of chemical compression of Eu sites in Ca0.9Eu0.1Co1.91As2 or direct electron doping in Ca0.85La0.15Co1.89As2. The results reported herein demonstrate the general possibility of amplifying minor localized electronic effects to achieve major changes in material's properties via involvement of strongly correlated electrons.

  5. Behavior of the positron beam of the Super-ACO storage ring in response to a modification of the RF frequency for free-electron laser experiments

    The macrotemporal structure of the Super-ACO Storage ring free-electron laser (FEL) can be either continuous, pulsed, or chaotic, and can present some rapid fluctuations. The temporal evolution of a storage ring FEL involves both the longitudinal motion of the positron beam (especially the synchrotron oscillations) and the FEL dynamics, as in a coupled system. Studies on the dynamics of the positron beam are performed here, in the goal to have a stable source for FEL applications, and to determine the conditions for a stable Q-switching experiment. The employed method is to study the influence of a controlled change of the radio frequency (RF) (modulation or frequency jump) on the beam. A simple theoretical model taking into account the perturbed RF system is presented to help the understanding of the experimental data. The different methods of measurement are described. Then, the results are given for several experimental conditions and the influence of different possible adjustments (synchrotron feedback, RF loop ...) is presented. Consequences are derived for the FEL

  6. Cytoplasmic CopZ-Like Protein and Periplasmic Rusticyanin and AcoP Proteins as Possible Copper Resistance Determinants in Acidithiobacillus ferrooxidans ATCC 23270.

    Navarro, Claudio A; von Bernath, Diego; Martínez-Bussenius, Cristóbal; Castillo, Rodrigo A; Jerez, Carlos A

    2016-02-01

    Acidophilic organisms, such as Acidithiobacillus ferrooxidans, possess high-level resistance to copper and other metals. A. ferrooxidans contains canonical copper resistance determinants present in other bacteria, such as CopA ATPases and RND efflux pumps, but these components do not entirely explain its high metal tolerance. The aim of this study was to find other possible copper resistance determinants in this bacterium. Transcriptional expression of A. ferrooxidans genes coding for a cytoplasmic CopZ-like copper-binding chaperone and the periplasmic copper-binding proteins rusticyanin and AcoP, which form part of an iron-oxidizing supercomplex, was found to increase when the microorganism was grown in the presence of copper. All of these proteins conferred more resistance to copper when expressed heterologously in a copper-sensitive Escherichia coli strain. This effect was absent when site-directed-mutation mutants of these proteins with altered copper-binding sites were used in this metal sensitivity assay. These results strongly suggest that the three copper-binding proteins analyzed here are copper resistance determinants in this extremophile and contribute to the high-level metal resistance of this industrially important biomining bacterium. PMID:26637599

  7. Avaliação da qualidade de vida pós-implante de marcapasso cardíaco artificial

    Tais Barbosa Gomes

    2011-12-01

    Full Text Available Este estudo teve como objetivo avaliar a qualidade de vida (QV de cardiopatas pós-implante de marcapasso (MP de uma cidade no interior de Goiás / Brasil. Estudo de intervenção tipo antes e depois. Vinte e três pacientes portadores de MP cardíaco foram avaliados antes e após implante de MP. Os instrumentos utilizados foram o AQUAREL associado ao SF-36. Houve predomínio de indivíduos do sexo feminino (65%, com idade média de 64,9 anos, e baixa escolaridade (43%. Os domínios que evidenciaram melhor QV, através do instrumento AQUAREL, foram desconforto no peito (M=71,60 e arritmia (M=70,87 e menor para dispneia ao exercício (M=61,81. Na comparação de QV antes e após o implante de MP, observou-se melhora significativa nos domínios do SF-36: capacidade funcional, dor, estado geral de saúde, aspecto social e aspecto emocional. De forma geral, os resultados do SF-36 indicam que houve melhora da qualidade de vida após implante de MP.

  8. Spontaneous rupture of a right atrial angiosarcoma and cardiac tamponade Ruptura espontânea de angiossarcoma atrial direito e tamponamento cardíaco

    Ricardo Barros Corso

    2003-12-01

    Full Text Available Primary cardiac angiosarcoma is a rare disease of difficult diagnosis and poor prognosis frequently associated with recurring hemopericardium. We report the case of a 30-year-old female with a right atrial angiosarcoma and spontaneous rupture to the pericardial cavity, who was diagnosed during an emergency exploratory thoracotomy, whose indication was cardiac tamponade. This is the 8th case reported in the literature. Clinical findings are discussed and a literature review is provided.O angiossarcoma primário do coração é uma doença rara, de diagnóstico difícil e de prognóstico reservado, freqüentemente associado ao hemopericárdio recidivante. Relatamos um caso de uma mulher de 30 anos, portadora de angiossarcoma atrial direito, com ruptura espontânea para a cavidade pericárdica, diagnosticada à toracotomia exploradora de urgência, indicada por tamponamento cardíaco. Trata-se do 8º caso descrito na literatura. São discutidos detalhes clínicos e revisão bibliográfica.

  9. Características do transplante cardíaco neonatal e infantil Characteristics of heart transplantation in neonates and infants

    Miguel Barbero-Marcial

    1996-06-01

    Full Text Available OBJETIVO: Relatar as características do transplante cardíaco neonatal e pediátrico em crianças portadoras de cardiopatias complexas e cardiomiopatias retratarias à terapêutica convencional. O presente trabalho mostra a experiência de três anos e meio deste procedimento no Instituto do Coração HC-FMUSP. MÉTODOS: A metodologia empregada consistiu-se na técnica cirúrgica nos casos de cardiopatias congênitas, critérios de indicação para o transplante e viabilidade do doador, manuseio pós-operatório, imunosupressão, prevenção e tratamento de potenciais complicações. RESULTADOS: De novembro de 1992 a junho de 1996, 14 crianças foram transplantadas com idade de 12 dias a seis anos (média de 2,2 anos; 57% do sexo masculino; peso de 3,5 kg a 17,8 kg (média de 10,3 kg. Os doadores tinham de 21 dias a dez anos de idade(média de 4,4 anos; 80% do sexo masculino; peso variando de 3,8 a 20 kg (média de 14,3 kg. A sobrevida foi de 85,7% (2 óbitos em 14 pacientes. O tempo de seguimento foi de um mês a três anos e seis meses (média de 16 meses. As principais complicações foram hipertensão arterial sistêmica, rejeição aguda e infecção. O número de rejeições por paciente foi de 3,5 episódios e de infecção foi de 3,3 episódios. CONCLUSÃO: O transplante cardíaco consistiu-se em promissora opção terapêutica com sobrevida de 85,7% a médio prazo.OBJECTIVE: Relate the characteristics of the heart transplantation in children with complex congenital heart diseases and severe cardiomyopathies. The present article was written to show the three year experience of this procedure at the Instituto do Coração HC-FMUSP. METHODS: The methodology used was based on surgical procedure in congenital heart disease, heart transplant indication criteria, inclusion criteria for donors, postoperative management, immunosupression and prophylaxis as well as treatment for potential complications. RESULTS: From November 1992 to June 1996

  10. Taponamiento cardíaco secundario a carcinoma papilar esclerosante difuso de tiroides Metastatic cardiac tamponade as initial manifestation of papillary thyroid carcinoma

    Verónica Riva

    2011-12-01

    Full Text Available El carcinoma papilar, variante esclerosante difusa, corresponde al 2% de todos los carcinomas papilares de la tiroides. Se caracteriza por comprometer de manera difusa y bilateral a la glándula tiroides. Clínicamente se manifiesta con metástasis ganglionares y pulmonares, afectando predominantemente a mujeres jóvenes. Se describe un caso de taponamiento cardíaco como presentación inicial de un carcinoma papilar de tiroides variante esclerosante difusa. Una mujer de 32 años concurrió al servicio de emergencias médicas refiriendo epigastralgia y tos seca. Durante el examen físico se constató hipotensión arterial, taquicardia y ruidos cardíacos disminuidos. Se realizó un ecocardiograma, observándose derrame pericárdico. Por medio de una pericardiocentesis se obtuvo líquido pericárdico, cuyo análisis mostró células neoplásicas. Durante la evolución la paciente presentó recurrencia del derrame pericárdico por lo que se realizó una ventana pleuropericárdica, detectándose durante la cirugía una lesión nodular subpleural, la cual fue biopsiada e informada posteriormente como una metástasis de carcinoma papilar vinculable a origen tiroideo. Se realizó una tiroidectomía total con linfadenectomía cervical bilateral. El diagnóstico final fue carcinoma papilar, variante esclerosante difusa. Esta variante infiltra el tejido conectivo de los espacios interfoliculares, simulando una tiroiditis y se caracteriza por una permeación vascular temprana. En oposición a la variante clásica, la esclerosante difusa presenta mayor agresividad y mayor tasa de recurrencia. El carcinoma papilar de tiroides debe tenerse presente como diagnóstico diferencial en nuestro medio, en todas aquellas lesiones neoplásicas papilares metastásicas, más aún si se trata de mujeres jóvenes.Papillary carcinoma, diffuse sclerosing variant corresponds to 2% of all papillary thyroid carcinomas. It is usually diffuse and bilateral, affecting the entire

  11. Improved ACO for protein structure prediction using 2D HP lattice model%改进的蚁群算法及其在2DHP模型中的应用

    周方; 廖波

    2009-01-01

    For improve the quality of solution to a Protein folding problem, ant colony optimization (ACO) is adopted to solve the protein folding simulations problem. Eliminate and clone based on the existing ACO is introduced. This ACO is applied in 2DHP model. At the same time, the ant colony will converge to local classic result easily when searching, and this process will infect the quality of the result. Avoiding the result converge to the local classic result, involving max-rain ant colony. Choose some HP sequence for the ex-periment. And experiment proved that the improvement have higher efficiency than the older one when the two arithmetic got the same optimal solution.%为了提高蛋白质折叠问题解的质量,采用蚁群算法对蛋白质的折叠问题进行研究,并且在现有的蚁群算法的基础上成功引入了淘汰和克隆机制,使其具有更好的运算效率,并成功应用到2DHP模型中.在蚁群对最优值进行搜索的过程中,容易出现局部最优点,导致影响解的质量.为了避免计算结果收敛到局部最优点,引入了一种最大最小蚁群策略.选择测试序列进行实验,实验结果表明,该算法在保证解的质量的同时,还具有较高的效率.

  12. Cintilografia de perfusão miocárdica e comprometimento cardíaco na fase indeterminada da doença de chagas Myocardial perfusion imaging and cardiac involvement in the indeterminate phase of chagas disease

    Amalia Peix; Raymid García; Jesús Sánchez; Lázaro O. Cabrera; Kenia Padrón; Oscar Vedia; Hugo V. Choque; Jorge Fraga; Juan Bandera; Alberto Hernández-Cañero

    2013-01-01

    FUNDAMENTO: A cintilografia de perfusão miocárdica (CPM) tem sido utilizada na avaliação da cardiopatia chagásica. OBJETIVO: Investigar o valor da CPM com tomografia computadorizada por emissão de fóton único (gated-SPECT) para detectar comprometimento cardíaco precoce em pacientes chagásicos na fase indeterminada, que apresentam anomalias de movimento segmentar detectadas por exame de imagem por Doppler tecidual (IDT) strain derivada. MÉTODOS: Foram incluídos 40 indivíduos (idade média: 25 ±...

  13. Revascularización coronaria incompleta y eventos cardíacos posteriores a intervencionismo coronario percutáneo Incomplete coronary revascularization and cardiac events following percutaneous coronary

    Amaury Flores Sánchez

    2012-06-01

    Full Text Available No hay datos concluyentes para evaluar la ventaja de la revascularización coronaria completa en el intervencionismo coronario percutáneo. Objetivo general: determinar si la revascularización incompleta se asocia con la incidencia de eventos cardíacos posteriores al intervencionismo coronario percutáneo. Métodos: se realizó una investigación observacional prospectiva con 192 pacientes con enfermedad coronaria multivaso, sin antecedentes de revascularización coronaria, tratados mediante intervencionismo coronario percutáneo con implantes de stents en el Instituto de Cardiología desde el 1 de enero del 2003 hasta el 31 de diciembre del 2005. Análisis estadístico: para determinar la asociación de la revascularización incompleta con eventos cardíacos se calculó el riesgo relativo. Resultados: al analizar la asociación de la revascularización incompleta con los eventos clínicos y los procederes cardíacos posteriores al intervencionismo coronario percutáneo, no se obtuvo relación alguna. Conclusiones: la revascularización coronaria incompleta no se asocia con mayor incidencia de eventos cardíacos posteriores a un intervencionismo coronario percutáneo con implantes de stents convencionales.No conclusive data are available to evaluate the advantages of complete coronary revascularization in percutaneous coronary intervention. General objective: Determine whether incomplete revascularization is associated with the incidence of cardiac events following percutaneous coronary intervention. Methods: A prospective observational study was conducted with 192 patients with multivessel coronary disease and no history of coronary revascularization, treated by percutaneous coronary intervention with stent implantation at the Institute of Cardiology from 1 January 2003 to 31 December 2005. Statistical analysis: Relative risk was estimated to determine the association of incomplete revascularization with cardiac events. Results: On analyzing

  14. Respostas cardiorrespiratórias durante exercício em portadores de transplante cardíaco. Análise ergoespirométrica comparativa com indivíduos normais

    Salles Ana Fátima; Oliveira Fº Japy Angelini; Barros Neto Turíbio Leite de; Almeida Dirceu Rodrigues; Carvalho Antonio Carlos de Camargo; Juliano Yara; Buffolo Ênio; Martinez Fº Eulógio Emílio

    1998-01-01

    OBJETIVO: Avaliar as respostas cardiorrespiratórias dos portadores de transplante cardíaco (TxC). MÉTODOS: Submeteram-se a testes ergoespirométricos 9 portadores de TxC (GI), pareados por sexo, idade, peso e altura, com 9 indivíduos sedentários, aparentemente sadios (GII). Os pacientes eram do sexo masculino, com idade de 48±12 anos, com TFI (NYHA) após 23±21 meses TxC. Faziam uso regular de ciclosporina, azatioprina, prednisona, dipiridamol e anti-hipertensivos. Os testes foram limitados por...

  15. Investigação de lipofuscina em miócitos cardíacos de camundongos após tratamento com oxamniquine Investigation of lipofuscin in cardiac miocytes of mice treated with oxamniquine

    Maria Luiza Silveira Mello; Carmen S. Bertuzzo

    1984-01-01

    A fluorescencia natural devida à presença de corpos de lipofuscina foi pesquisada em miócitos cardíacos de camundongos adultos jovens tratados com oxamniquine. O objetivo foi buscar uma evidência de indução de envelhecimento celular precoce, com base em dados prévios de acentuação poliploidia, promovida pela droga. Comparando o miocárdio dos camundongos tratados com animais contrôle jovens e velhos, não foi observada a presença de lipofuscina nos seus miócitos. Isto possivelmente se deva a um...

  16. Transplante cardíaco (TC: a experiência do portador da doença de Chagas Trasplante cardíaco (TC: la experiencia del portador de la enfermedad de Chagas Heart transplantation: the experience of patients with Chagas disease

    Maria Lúcia Araújo Sadala

    2009-09-01

    Full Text Available O sucesso do transplante cardíaco com portadores da doença de Chagas está condicionado a cuidados especiais durante todas as fases do transplante, com necessidade de acompanhamento específico e rigoroso pela equipe de saúde. Os receptores devem estar conscientes da permanência do Trypanossoma no organismo, e das possibilidades de reativação da infecção após o transplante. Portanto, seu conhecimento dessa condição, e a sua participação ativa no próprio tratamento, têm importância fundamental. O objetivo do estudo foi investigar a experiência do transplante cardíaco vivenciada por pacientes portadores da doença de Chagas, para buscar compreender os significados que eles atribuem a esta experiência. Os procedimentos metodológicos abrangeram: a seleção dos pacientes; as entrevistas; a análise dos dados, indicando as unidades de significado e a análise individual; a busca de convergências dos discursos; e análise hermenêutica das convergências. Da análise dos dados emergiram os seguintes temas: o tempo vivido pelo receptor, portador da Doença de Chagas; a concepção do TC apresentado pelo portador de Chagas; o cuidado na trajetória do TC.El éxito del trasplante cardíaco con portadores de la enfermedad de Chagas está condicionado a cuidados especiales durante todas las fases del trasplante, con necesidad de acompañamiento específico y riguroso por el equipo de salud. Los receptores deben estar conscientes de la permanencia del Tripanosoma en el organismo y de las posibilidades de reactivación de la infección después del trasplante. Por lo tanto, su conocimiento sobre esa condición y su participación activa en el propio tratamiento es de fundamental importancia. El objetivo del estudio fue investigar la experiencia del trasplante cardíaco experimentada por pacientes portadores de la enfermedad de Chagas, para comprender los significados que ellos atribuyen a esta experiencia. Los procedimientos metodol

  17. Cintilografia de perfusão miocárdica e comprometimento cardíaco na fase indeterminada da doença de chagas

    Amalia Peix

    2013-02-01

    Full Text Available FUNDAMENTO: A cintilografia de perfusão miocárdica (CPM tem sido utilizada na avaliação da cardiopatia chagásica. OBJETIVO: Investigar o valor da CPM com tomografia computadorizada por emissão de fóton único (gated-SPECT para detectar comprometimento cardíaco precoce em pacientes chagásicos na fase indeterminada, que apresentam anomalias de movimento segmentar detectadas por exame de imagem por Doppler tecidual (IDT strain derivada. MÉTODOS: Foram incluídos 40 indivíduos (idade média: 25 ± 2 anos, 50% homens de uma área endêmica da doença de Chagas e com diagnóstico sorológico positivo. Todos foram submetidos à CPM com gated-SPECT de 2 dias (repouso e estresse e ecocardiografia. RESULTADOS: Trinta indivíduos (75% apresentaram resultados normais. Em três casos (8%, a CPM apresentou resultado ligeiramente anormal e em sete foi ambígua. Em todos os casos com defeitos reversíveis, os segmentos afetados foram coincidentes com aqueles com anomalias de movimento. Foi encontrada redução na fração de ejeção ventricular esquerda (FEVE > 5% (ΔLVEF% < -5 pós-estresse em 11 dos 40 indivíduos (28%. Tanto o desvio padrão fasederivado como a largura da banda do histograma mostraram diferença significativa entre o pós-estresse e a fase de repouso. Em ambos os casos, houve ligeira dessincronia em repouso normalizado no pós-estresse. CONCLUSÃO: Uma abordagem estresse-repouso com gated-SPECT é válida para detectar alterações miocárdicas precoces, bem como dessincronia intraventricular na fase indeterminada da doença de Chagas em pacientes com anomalias no movimento segmentar previamente detectadas pela IDT strain derivada.

  18. La iluminación agustiniana como explicación de los contenidos de la mente: Agustín en Casicíaco

    Óscar Velásquez

    2007-01-01

    Full Text Available Se examina en este trabajo la teoría agustiniana de la iluminación del período de Casicíaco. Lo temprano de su manifestación revela su carácter más filosófico que teológico. Proteo es figura de la verdad que se resiste a darse a conocer, pero que mediante la auctoritas (Cristo y la ratio puede ser hallada, como se muestra en Contra Académicos. De este modo, en Soliloquios, la ratio se presenta como mediadora entre el alma y Dios. Se utiliza aquí la oración como método de introspección e investigación filosófica. Se concluye que la iluminación abarca tanto la verdad objetiva como al receptor de esa verdad, la mente; y que esa misma mente en que las verdades eternas son reconocidas debe ser inmortal, como aquellas lo son: así, la senda que conduce al conocimiento de Dios, pasa por el conocimiento de nosotros mismosAugustine's Theory of Illumination from the Cassisiacum period is examined in this work. The early appearance of the theory reveals its character as of a more philosophical than theological kind. Proteus is a figure of the truth resisting discovery, but which can be found through auctoritas (Christ and ratio as it is shown in Contra Académicos. Thus ratio shows itself in Soliloquia as mediating between the soul and God. Prayer as a method of introspection and philosophical research is used. The author concludes that illumination includes as much the objective truth as the receiver of that truth-the mind; and that this same mind, in which the eternal truths are recognized, must be immortal, as they themselves are. In this way, the path which leads to the knowledge of God passes through the knowledge of our very selves

  19. Incidência de coronariopatia após o transplante cardíaco ortotópico Incidence of coronariopathy after orthotopic heart transplantation

    Alfredo I Fiorelli

    1994-06-01

    Full Text Available O presente estudo tem por finalidade analisar tardiamente o padrão anatômico evolutivo das artérias coronárias do coração transplantado. Para cumprir tal proposição foram selecionados 22 pacientes submetidos ao transplante cardíaco ortotópico, com seguimento pós-operatório superior a 36 meses. As variáveis eleitas para este fim foram aferidas anualmente até o quinto ano de pós-operatório. A análise da ventriculografia mostrou a estabilidade da fração de ejeção (p=0,99 em valores normais. A cineangiocoronariografia seqüencial evidenciou incidência crescente de lesões arteriais com comprometimento da função contrátil. As lesões obstrutivas acometeram as artérias coronárias difusamente, com predomínio no território distai. Os episódios de rejeição aguda e a etiologia da cardiomiopatia não modificaram a evolução natural da aterosclerose coronária.The purpose of this study was to analise late anatomical status of coronary arteries in patients (pts in whom orthotopic heart transplantation(OHT was perfomed. We studied 22 pts submitted to OHT with post-operative follow-up longer than 36 months. They were evaluated by cinecoronariography every year in a 5 years follow-up. Ventriculography analisis showed stability (in normal values of the left ventricular ejection fraction (p= 0,99 during the follow-up period. The sequential coronary studies showed a progressive increase on incidence of abnormalities in coronary arteries with disorders of contratile function. The obstructive abnormalities were present in all segments but more in distal territories. The acute rejection episodes and cardiomiopathy etiologies didn't change the natural evolution of coronary atherosclerosis.

  20. ANÁLISIS DE LA CALIDAD DEL REGISTRO DE PARO CARDÍACO EN CASOS DE RESPONSABILIDAD MÉDICO LEGAL EN MÉDICOS GENERALES, 1999-2007 Quality of cardiac arrest records in cases of medical responsibility, 1999-2007

    Gabriel Barragán; José Ricardo Navarro; Nathalie Marulanda; Javier Eslava Schmalbach

    2009-01-01

    Antecedentes. El registro del paro cardíaco es una actividad que se debe acompañar en la reanimación cerebro cardio pulmonar. En Colombia no existe un formato de registro oficial de paro cardiorrespiratorio, lo que dificulta la investigación en reanimación y la conducción de los procesos de responsabilidad médica que se deriven de esta atención. Objetivo. Analizar la calidad del registro de paro cardíaco en casos de responsabilidad médico legal iniciada a médicos generales que tuvieron asesor...

  1. ACO based routing for MANETs

    Arif, Mohammad

    2012-01-01

    Mobile ad hoc network (MANET) is a collection of wireless mobile nodes. It dynamically forms a temporary network without using any pre existing network infrastructure or centralized administration i.e. with minimal prior planning. All nodes have routing capabilities and forward data packets to other nodes in multi-hop fashion. As the network is dynamic, the network topology continuously experiences alterations during deployment. The biggest challenge in MANETs is to find a path between communicating nodes. The considerations of the MANET environment and the nature of the mobile nodes create further complications which results in the need to develop special routing algorithms to meet these challenges. Swarm intelligence, a bio-inspired technique, which has proven to be very adaptable in other problem domains, has been applied to the MANET routing problem as it forms a good fit to the problem. In ant societies the activities of the individuals are not regulated by any explicit form of centralized control but ar...

  2. ACO Based Routing for MANETs

    Mohammad Arif

    2012-05-01

    Full Text Available Mobile ad hoc network (MANET is a collection of wireless mobile nodes. It dynamically forms atemporary network without using any pre existing network infrastructure or centralized administrationi.e. with minimal prior planning. All nodes have routing capabilities and forward data packets to othernodes in multi-hop fashion. As the network is dynamic, the network topology continuously experiencesalterations during deployment. The biggest challenge in MANETs is to find a path betweencommunicating nodes. The considerations of the MANET environment and the nature of the mobile nodescreate further complications which results in the need to develop special routing algorithms to meet thesechallenges. Swarm intelligence, a bio-inspired technique, which has proven to be very adaptable in otherproblem domains, has been applied to the MANET routing problem as it forms a good fit to the problem.In ant societies the activities of the individuals are not regulated by any explicit form of centralizedcontrol but are the result of self-organizing dynamics driven by local interactions and communicationsamong a number of relatively simple individuals. This unique characteristic has made ant societies anattractive and inspiring model for building new algorithms and new multi-agent systems. In this paper,we have studied and reviewed Ant Colony based routing algorithms and its variants. Finally, aperformance evaluation of the original ARA and the EARA is carried out with respect to each other.

  3. Consulta de enfermagem ao cliente transplantado cardíaco: impacto das ações educativas em saúde Consulta de Enfermería al cliente trasplantado cardíaco: impacto de las acciones en salud Appointment with nurses for transplanted heart clients: impact of educative health actions

    Zélia Maria de Sousa Araújo Santos

    2004-12-01

    Full Text Available O estudo teve como objetivo avaliar o impacto das ações educativas em saúde, na consulta de Enfermagem com 18 clientes transplantados cardíacos, embasado na Teoria de Orem. Foi realizado em uma Unidade de Transplante e Insuficiência Cardíaca de uma Instituição Pública de Saúde de Fortaleza - Ce. Os dados foram coletados através da consulta de Enfermagem. Identificou-se 14 diagnósticos de enfermagem na primeira consulta e 7 na última. Constatou-se que, os clientes desenvolveram habilidades para o autocuidado, com a implementação das ações educativas em saúde, tornando-os agentes de autocuidado, com o alcance de um bom nível de saúde e bem-estar. Por outro lado, despertou no enfermeiro, um direcionamento sistemático e eficaz no acompanhamento ambulatorial a esta clientela.El estudio tiene como objetivo, evaluar el impacto de las acciones educativas en salud, en la consulta de Enfermería con 18 cliente trasplantados cardíacos, basado en la teoría de Orem. Se realizó en una Unidad de Trasplante e Insuficiencia Cardiaca de una Institución Pública de Fortaleza-Ce. Se colectaron los datos a través de consulta de enfermería. Se identificaron 14 diagnósticos en la primera consulta y 7 en la última. Hubo la constatación de que, los clientes desarrollaron habilidades para el autocuidado, con la implementación de las acciones educativas en salud, volviéndose agentes de autocuidado, con el alcance de un buen nivel de salud y bienestar. Por otro lado, estimuló en el enfermero, una dirección sistemática y eficaz en el acompañamiento ambulatorial a esta clientela.The study was aimed at evaluating the impact of educative health actions on nursing appointments with 18 transplanted heart clients, based on Orem's Theory. It was conducted in a Heart Transplant and Insufficiency Unit of a Public Health Institution in Fortaleza - CE. The data were collected by way of nursing appointments. 14 nursing diagnoses were identified in

  4. Espectro óculo-aurículo-vertebral em pacientes com defeitos cardíacos congênitos Espectro óculo-aurículo-vertebral en pacientes con defectos cardíacos congénitos Oculo-auriculo-vertebral spectrum in patients with congenital heart defects

    Rafael Fabiano Machado Rosa

    2010-10-01

    Full Text Available FUNDAMENTO: Há poucos estudos avaliando a frequência do espectro óculo-aurículo-vertebral (EOAV nos pacientes com defeitos cardíacos congênitos (DCC. OBJETIVO: Verificar a frequência do EOAV em uma amostra de pacientes com malformações cardíacas graves. MÉTODOS: Avaliamos uma coorte prospectiva de pacientes com DCC, admitidos em uma unidade de terapia intensiva (UTI cardiopediátrica no Brasil. O diagnóstico de EOAV foi feito com base em dados clínicos, considerando critérios padrões. Os pacientes que preenchiam esses critérios foram submetidos ao cariótipo de alta resolução com bandamento GTG e hibridização fluorescente in situ para a microdeleção 22q11.2. O teste exato de Fisher (P FUNDAMENTO: Hay pocos estudios evaluando la frecuencia del espectro óculo-aurículo-vertebral (EOAV en los pacientes con defectos cardíacos congénitos (DCC. OBJETIVO: Verificar la frecuencia del EOAV en una muestra de pacientes con malformaciones cardíacas graves. MÉTODOS: Evaluamos una cohorte prospectiva de pacientes con DCC, admitidos en una unidad de terapia intensiva (UTI cardiopediátrica en el Brasil. El diagnóstico de EOAV fue hecho con base en datos clínicos, considerando criterios estándares. Los pacientes que llenaban esos criterios fueron sometidos al cariotipo con bandeamiento GTG en alta resolución e Hibridización fluorescente in situ para la microdelección 22q11.2. El Test Exacto de Fisher (P BACKGROUND: There have been few studies evaluating the frequency of oculo-auriculo-vertebral spectrum (OAVS in patients with congenital heart defects (CHDs. OBJECTIVE: To verify the frequency of OAVS in a sample of patients with major heart malformations. METHODS: We evaluated a prospective cohort of patients with CHD admitted in a pediatric cardiac intensive care unit (ICU in Brazil. The diagnosis of OAVS was made based on the clinical data, considering standard criteria. The patients that met these criteria were submitted to

  5. Cardiac lesions in patients with lethal central nervous system trauma Daño cardíaco en pacientes con trauma mortal del sistema nervioso central

    María E. Cardona

    1991-03-01

    ño cardíaco comprobado por el estudio anatomopatológico, la fracción MB resultó por encima del valor normal. En 6 pacientes (40% se encontraron lesiones cardíacas; las más comunes fueron las hemorragias subendocárdicas. Se llama la atención hacia la importancia de las lesiones cardíacas ya que los pacientes que fallecen por traumatismo craneoencefálico son donadores potenciales de órganos para trasplante.

  6. Percepção dos indivíduos celíacos acerca da contaminação dos cosméticos com glúten

    Ivanilde Miciele da Silva Santos; Diogo Guedes Peixoto; Emília Patrícia de Oliveira Costa Brito

    2015-01-01

    A exclusão do glúten na dieta por toda a vida é o único tratamento com eficácia inquestionável para a doença celíaca (DC), o qual mesmo em pequenas quantidades pode ser prejudicial à saúde. Recentes discussões na comunidade científica sugerem que, além da dieta, devem ser excluídos também medicamentos, produtos de higiene e cosméticos que possam conter traços de glúten. Assim, este trabalho visou verificar o grau de conhecimento dos celíacos acerca da provável influência dos cosméticos no agr...

  7. Preliminary study on polymorphism of ACO gene in six varieties of sweet cherry ( Prunus avium )%6个甜樱桃品种ACO基因多态性的检测

    王廿; 张开春; 王晶; 张晓明; 闫国华

    2012-01-01

    乙烯在植物果实成熟过程中起着重要的作用,ACC合酶(1-aminocyclop ropane-1-carboxylic acid synthase,ACS)和ACC氧化酶(1-aminocyclop ropane-1-carboxylic acid oxidase,ACO)是植物乙烯生物合成途径的限速酶。通过DNA序列分析,以不同果实成熟期的6个甜樱桃品种(Prunus avium L.)为材料,检测ACO基因的多态性。获得甜樱桃ACO基因约1kh,与桃(Ppersica)ACO基因(GenBank登录号:AF532976)序列的同源性达96%,其预测的氨基酸序列与桃、梅(Pmume)、美洲李(Parmeniaca)和欧洲李(Pdomestica)等ACO的氨基酸序列同源性超过95%。该片段包括4个外显子和4个内含子,内含子符合GT—AT规律。用DNAMAN进行多序列比对分别在内含子2和内含子4内发现2个多态性简单重复序列(AT)n。内含子2有3种片段:即(AT)6、(AT)7和(AT)8;内含子4有2种片段,即(AT)5和(AT)6,组合后共得到4种ACO单倍型。研究在甜樱桃ACO基因座上发现2个SSR标记,为进一步研究4CD基因多态性与果实成熟期相关性奠定基础。%Ethylene plays an important role in ripening of plants. ACC synthease ( 1-aminocyclop ropane- 1-carboxylic acid synthase, ACS) and ACC oxidase (1-aminocyclop ropane-1-carboxylic acid oxidase, ACO) are rate-limiting enzymes in ethylene biosynthesis in plants. DNA sequence analysis was applied to detect the polymorphism of A CO gene in 6 sweet cherry varieties (Prunus avium L.) of different maturity time. The DNA sequences of partial A CO gene about 1 kb were obtained from sweet cherry (P. avium). The identity of these DNA sequences was 96% with A CO of peach (P. persica). The identity of predicted amino acid sequences was 95% with the amino acid sequence of ACO in P. persica, Prunus mume, Prunus armeniaca, and Prunus domestica. These fragments contained four extrons and four introns which has GT-AG sequence. Two SSR markers

  8. Uso de fluorescência em um método de dissector modificado para estimar o número de miócitos no tecido cardíaco

    2012-01-01

    FUNDAMENTO: Métodos convencionais de dissector atualmente requerem consideráveis custos financeiros, técnicos e operacionais para estimar o número de células, incluindo cardiomiócitos, em uma área de 3D. OBJETIVO: Usar a microscopia de fluorescência em um método de dissector modificado para determinar o número de miócitos no tecido cardíaco em condições normais e patológicas. MÉTODOS: O estudo empregou camundongos Wistar machos com quatro meses de idade e peso de 366,25 ± 88,21 g randomizados...

  9. Uso de fluorescência em um método de dissector modificado para estimar o número de miócitos no tecido cardíaco Uso de fluorescencia en un método de disector modificado para estimar el número de miocitos en el tejido cardíaco Use of fluorescence in a modified disector method to estimate the number of myocytes in cardiac tissue

    Rômulo Dias Novaes; Arlete Rita Penitente; André Talvani; Antônio José Natali; Clóvis Andrade Neves; Izabel Regina Santos Costa Maldonado

    2012-01-01

    FUNDAMENTO: Métodos convencionais de dissector atualmente requerem consideráveis custos financeiros, técnicos e operacionais para estimar o número de células, incluindo cardiomiócitos, em uma área de 3D. OBJETIVO: Usar a microscopia de fluorescência em um método de dissector modificado para determinar o número de miócitos no tecido cardíaco em condições normais e patológicas. MÉTODOS: O estudo empregou camundongos Wistar machos com quatro meses de idade e peso de 366,25 ± 88,21 g randomizados...

  10. Utilidade do Ultrassom intracardíaco no isolamento de veias pulmonares usando cateter-balão a laser Utilidad del ultrasonido intracardíaco en el aislamiento de venas pulmonares usando catéter-balón láser Utility of intracardiac ultrasound imaging to guide pulmonary vein ablation using laser balloon catheter

    Luiz Leite

    2009-12-01

    Full Text Available FUNDAMENTO: O isolamento das veias pulmonares (IVP tem sido usado como endpoint para a ablação da fibrilação atrial (FA com cateter balão. OBJETIVO: Determinar a utilidade do ultrassom intracardíaco (USIC para guiar o IVP, usando cateter balão a laser. MÉTODOS: 59 VP foram ablacionadas em 27 cães. Imagens de Doppler foram usadas para identificar os vazamentos do fluxo sanguíneo entre a VP e o balão. Após cada liberação de energia, o cateter de mapeamento circular foi reposicionado para verificar se o isolamento tinha sido obtido. A posição de vazamento foi então correlacionada com a posição do gap no estudo patológico. A análise de regressão logística multivariada foi realizada. RESULTADOS: Cinquenta e nove VP foram submetidas à ablação. O tempo médio de energia liberada foi de 279±177 seg., o diâmetro médio do balão era de 23±3 mm, e o comprimento médio do balão era 25±4 mm. O isolamento completo foi obtido em 38/59 (64%, e foi significantemente mais comum sem vazamento: [30/38 (79% versus 8/23 (35%, pFUNDAMENTO: Se usó el aislamiento de las venas pulmonares (AVP como endpoint para la ablación de la fibrilación atrial (FA con catéter-balón. OBJETIVO: Determinar la utilidad del ultrasonido intracardíaco (USIC para guiar el AVP, usando catéter-balón láser. MÉTODOS: Se ablacionaron 59 VP en 27 perros. Se usaron imágenes de Doppler para identificar los derrames del flujo sanguíneo entre la VP y el balón. Tras cada liberación de energía, se reposicionó el catéter de mapeamiento circular para verificar si se obtuvo el aislamiento. Se correlaccionó, entonces, la posición del derrame con la posición del gap en el estudio patológico. Se realizó el análisis de regresión logística multivariada. RESULTADOS: Se sometieron 59 VP a la ablación. El tiempo promedio de energía liberada fue de 279±177 seg., el diámetro promedio del balón era de 23±3 mm, y la largura promedio del balón era 25±4 mm

  11. Baixas doses de óxido nítrico na seleção dos pacientes candidatos a transplante cardíaco com hipertensão pulmonar Low doses of nitric oxide in the selection of candidates to heart transplantation with pulmonary hypertension

    MEJIA Juan Alberto Cosquillo; Valdester Cavalcante PINTO Jr; BARROSO Haroldo Brasil; de Mesquita, Fernando Antônio; Waldomiro CARVALHO Jr.; CASTELO BRANCO José Matos Brito; SOUZA Flávio José Rocha; Maria Corina Amaral VIANA; SOUSA Patrícia Lopes; João David SOUSA NETO

    2001-01-01

    A disfunção do ventrículo direito no pós-operatório do transplante cardíaco é uma complicação freqüente com morbimortalidade elevada. A avaliação hemodinâmica pulmonar dos candidatos precisa, às vezes, do emprego de prova farmacológica com o uso de drogas endovenosas vasodilatadoras tipo nitroprussiato de sódio (NTPNa), visando reduzir os níveis de pressão e resistência vascular pulmonar (RVP) elevados a níveis compatíveis com os protocolos de inclusão dos Programas de Transplante Cardíaco. V...

  12. Dosagem de marcadores cardíacos CK-MB e TnIc e eletrólitos no envenenamento experimental por veneno de sapo em cães

    Annelise C. Camplesi

    2009-08-01

    Full Text Available Dentre os sinais sistêmicos causados pelo envenenamento por veneno de sapo (bufotoxina em cães, os efeitos cardiotóxicos são um dos mais importantes. O objetivo deste estudo foi avaliar as potenciais alterações no músculo cardíaco de cães envenenados experimentalmente por veneno de sapo e observar as alterações eletrolíticas que podem ocorrer nesse tipo de envenenamento. Utilizaram-se 20 cães divididos em grupo controle (n=5 e grupo envenenado (n=15. O veneno de sapo foi extraído por meio de compressão manual das glândulas paratóides. Após anestesia geral, os cães do grupo controle receberam placebo (solução fisiológica e os do grupo envenenado uma alíquota do veneno por sonda orogástrica. As colheitas de sangue para dosagem dos marcadores cardíacos foram realizadas seis e 24 horas após o envenenamento. As colheitas de sangue para dosagem dos eletrólitos foram realizadas antes e duas, quatro, seis e 12 horas após o envenenamento. A análise estatística empregada foi o teste não-paramétrico de Mann-Withney (PAmong the systemic signs of toad venom (bufotoxin poisoning in dogs, the cardiotoxic effects are one of the most important. Thus, the objective of this experiment was to evaluate potential changes in the cardiac muscle in dogs poisoned experimentally by toad venom and to observe the eletrolyte alterations which may occur in this condition. Twenty dogs divided into control group (n=5 and poisoned group (n=15 were utilized. The toad venom was extracted by manual compression of the paratoidic glands. After general anesthesia, dogs in the control group received placebo and dogs in the poisoned group received the venom by orogastric catheter. Samples for dosage were collected 6 hours and 24 hours after poisoning and 0, 2, 4, 6 and 12 hours after poisoning for electrolytes dosage. The Man-Withney test was used for statistical analysis (P<0.05. The poisoned dogs showed (saline elevated levels of cardiac markers CK

  13. Avaliação ecocardiográfica do desenvolvimento cardíaco de cavalos atletas: comparação entre atividades físicas distintas

    Carolina C.M. Bonomo

    2014-09-01

    Full Text Available A capacidade aeróbica dos equinos atletas pode ser explicada, em partes, pelo seu desenvolvimento cardíaco associado ao treinamento físico. O exame ecocardiográfico de equinos atletas permite a visualização destas alterações e da função cardíaca destes animais. Buscou-se avaliar ecocardiograficamente equinos de diferentes modalidades esportivas, para verificar se o tipo de atividade física desempenhada por cada grupo de animais promove diferenças estruturais ou funcionais cardíacas. 196 equinos foram submetidos à avaliação ecocardiográfica em repouso, sendo divididos em três grupos: grupo Polo, 44 equinos participantes de provas de Polo; grupo QM, 49 equinos da raça Quarto de Milha, participantes de provas de baliza e tambor, e grupo PSI, 103 equinos da raça Puro Sangue Inglês participantes de provas de corridas. Foram avaliados os seguintes índices cardíacos: SIV, DIVE e PLVE em sístole e diástole, AE em sístole, Ao em diástole, relação AE:Ao, FEj, VEj, VSFVE, VDFVE, FS%, E-S, TEVE, DC e FC. Os animais do grupo PSI apresentaram os maiores volumes de ventrículo esquerdo, tendo apresentado proporcionalmente menor eficiência quando analisado o VEj. Os animais do grupo Polo e QM apresentaram melhores valores quando analisadas as variáveis de função cardíaca. A atividade física mais intensa desempenhada pelos animais do grupo QM e Polo permitiu melhor desenvolvimento funcional do coração destes animais, tendo o grupo PSI, apresentado valores que sugerem que sua capacidade aeróbica ainda pode ser melhor explorada através de melhor orientação de seu treinamento físico.

  14. Efeitos do propofol sobre o sistema de condução cardíaca Efectos del propofol sobre el sistema de conducción cardíaco Effects of propofol on the cardiac conduction system

    Paulo Warpechowski

    2010-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Alguns estudos têm demonstrado que o uso do propofol é, algumas vezes, associado a bradiarritmias ou reversão de arritmias para ritmo sinusal. Essa propriedade do propofol sugere interferência no Sistema de Condução Cardíaco (SCC. CONTEÚDO: Realizou-se revisão com base nos principais artigos contemporâneos que englobam o uso do propofol na presença de arritmias cardía cas. Os autores discorrem sobre os mecanismos fisiopatológicos das taquiarritmias supraventriculares (TSV e as eventuais interferências causadas pelo propofol sobre o SCC. CONCLUSÕES: Os estudos realizados até então parecem indicar que, provavelmente, o propofol interfere nas TSV automáticas (pelo menos em crianças, mas não nas taquiarritmias em que o mecanismo seja de reentrada.JUSTIFICATIVA Y OBJETIVOS: Algunos estudios han demostrado que el uso del propofol es algunas veces, asociado a bradiarritmias o a reversión de arritmias para ritmo sinusal. Esa propiedad del propofol nos sugiere una interferencia en el Sistema de Conducción Cardíaco (SCC. CONTENIDO: Se realizó una revisión en base a los principales artículos contemporáneos que engloban el uso del propofol cuando ocurren arritmias cardíacas. Los autores nos hablan sobre los mecanismos fisiopatológicos de las taquiarritmias supraventriculares y las eventuales interferencias causadas por el propofol sobre el SCC. CONCLUSIÓN: Los estudios realizados hasta ahora parecen indicar que probablemente, el propofol interfiere en las TSV automáticas (por lo menos en niños, pero no en las taquiarritmias en que el mecanismo sea de reentrada.BACKGROUND AND OBJECTIVES: Some studies have demonstrated that the use of propofol is occasionally associated with bradyarrhythmias or reversion of arrhythmias to sinus rhythm. This property of propofol suggests interference with the Cardiac Conduction System (CCS. CONTENTS: A review of the main contemporary articles on the use of propofol in

  15. Soplos cardíacos fisiológicos y patológicos en el caballo de deporte. Su diagnóstico diferencial Physiological and pathological cardiac murmurs in the sport of horse. Its differential diagnosis

    G Pidal

    2010-06-01

    Full Text Available Los autores describen las pautas utilizadas para mejorar el diagnóstico diferencial entre los soplos patológicos y los soplos fisiológicos en el caballo, particularmente en los utilizados en deportes ecuestres. Asimismo, presentan la incidencia encontrada en la población estudiada de los soplos funcionales según válvula afectada y uso del caballo. Finalmente hace referencia al "error diagnóstico" en la clasificación de los soplos (patológicos / fisiológicos cuando son estudiados por medio de la semiología clásica (auscultación y luego de la utilización de exploraciones complementarias como la ecocardiografía bidimensional y el Doppler cardíaco.The authors describe the guidelines used to improve the differential diagnosis between physiological and pathological murmurs in horses, particularly those used in equestrian sports. They also present the incidence of functional murmurs, valve affected and use of the horse found in the population studied. Finally refer to "diagnostic error" in the classification of murmurs (pathological / physiological when studied by clinical evaluation (auscultation and after the use of complementary studies as bidimensional echocardiography and cardiac Doppler.

  16. Estimación del gasto cardíaco: Utilidad en la práctica clínica. Monitorización disponible invasiva y no invasiva Estimating cardiac output: Utility in the clinical practice. Available invasive and non-invasive monitoring

    X. García

    2011-12-01

    Full Text Available Esta revisión pretende profundizar en el conocimiento del gasto cardíaco, sus variables y sus condicionantes, así como repasar exhaustivamente las diferentes técnicas disponibles para su monitorización y establecer las situaciones en que el conocimiento del gasto cardíaco nos aporta una información fundamental en el manejo del paciente crítico. La técnica de Fick, utilizada en los inicios para calcular el gasto cardíaco de los pacientes, ha sido sustituida hoy en día en la práctica clínica por los métodos de termodilución (transcardíaca o transpulmonar, litiodilución, biorreactancia, la tecnología basada en el efecto Doppler o la ecocardiografía. El análisis de la onda de pulso ha permitido la obtención de una medida continua y mínimamente invasiva del gasto cardíaco. Otros métodos, como la biorrectancia, el Doppler o la ecocardiografía nos permiten, en la actualidad, obtener medidas del gasto cardíaco de forma no invasiva, rápida y fiable.This aim of this review is to provide a detailed review of the physiologic conditions and variables of the cardiac output, as well as review the different techniques available for its measurement. We also want to establish the clinical situations in which the measurement of cardiac output can add valuable information for the management of critically ill patients. The Fick technique, used in the beginning to calculate cardiac output, has been replaced today by thermodilution techniques (transcardiac or transpulmonary, lithium dilution, bioreactance, Doppler technique or echocardiography. Pulse wave analysis allows a continuous minimally invasive cardiac output measurement. Other methods, such bioreactance, Doppler technique or echocardiography currently provide a valid, fast and non-invasive measurement of cardiac output.

  17. EVALUACIÓN ECOCARDIOGRÁFICA DEL GASTO CARDÍACO SISTÉMICO EN LA ATRESIA PULMONAR CON SEPTO INTERVENTRICULAR INTACTO / Echocardiographic evaluation of cardiac output in pulmonary atresia with intact ventricular septum

    Giselle Serrano Ricardo

    2013-07-01

    Full Text Available Resumen: Introducción: El estudio de la atresia pulmonar con septo interventricular intacto no ha prestado suficiente atención al carácter dual del ventrículo izquierdo como receptor circulatorio y su repercusión sobre la hemodinámica sistémica. Objetivo: Identificar, mediante la ecocardiografía, los elementos fisiopatológicos propios de esa enfermedad que perfilan su actuación hemodinámica de base, influyen sobre el gasto cardíaco y generan condiciones potenciales para el pronóstico a corto plazo. Método: Se realizó una investigación con carácter descriptivo, prospectivo y aplicado, donde se estudiaron 43 pacientes con diagnóstico de la enfermedad remitidos al Cardiocentro Pediátrico "William Soler" desde enero de 1992 a noviembre de 2011. Se evaluaron, en cada sujeto, los perfiles de ocho variables ecocardiográficas y de la frecuencia cardíaca. Se analizaron los niveles de asociación y dependencia entre ellas mediante la aplicación estadística de modelos de regresión simple. Resultados: Existen variaciones considerables en la frecuencia cardíaca, en el índice volumétrico y en la fracción de eyección correspondientes al ventrículo izquierdo de los pacientes respecto al grupo control de referencia. Conclusiones: El mayor tamaño de la comunicación interauricular y la prolongación de la diastasis transmitral favorecen el incremento volumétrico del ventrículo izquierdo. La frecuencia cardíaca, el carácter restrictivo del miocardio ventricular izquierdo y su fracción de eyección son factores reguladores del gasto cardíaco en esta enfermedad. / Abstract: Introduction: In the study of pulmonary atresia with intact ventricular septum, not enough attention has been paid to the dual nature of the left ventricle as a circulatory receptor, and its impact on systemic hemodynamics. Objective: To identify, by echocardiography, the pathophysiological elements that characterize the disease and that determine its basic

  18. Osteotomia proximal da tíbia: estabilização da abertura medial com enxerto tricortical de ilíaco Proximal tibial osteotomy: stabilization of the medial opening with atricortical iliac bone graft

    Roberto da Cunha Luciano

    2010-01-01

    Full Text Available OBJETIVO: Avaliação radiográfica do alinhamento do membro inferior, nos planos frontal e sagital, após osteotomia alta da tíbia. Para estabilização da osteotomia foi utilizado enxerto tricortical de ilíaco e parafuso de posicionamento. MÉTODOS: Estudo prospectivo envolvendo 46 pacientes com idade entre 17 e 61 anos, sendo 42 portadores de geno varo secundário à osteoartrose e quatro por outras causas. A telerradiografia foi realizada para planejamento cirúrgico, utilizando o método de Frank Noyes modificado por Fugizawa. Foi realizado acesso cirúrgico convencional de 3cm para retirada do enxerto tricortical de ilíaco. A osteotomia foi realizada sob controle de radioscopia, por incisão anteromedial de 3cm com liberação da porção superficial do ligamento colateral medial. O enxerto foi colocado na porção posterior da osteotomia, para manter inalterado o slope tibial. O parafuso cruzou a osteotomia ortogonalmente para proteger a cortical lateral. Foram estabelecidos critérios radiográficos pré e pós-operatórios para avaliação dos resultados. RESULTADOS: Houve consolidação em 100% dos casos e manutenção do eixo mecânico, obtido no intraoperatório, em 94%. A inclinação posterior do platô tibial, no plano sagital, variou entre 7º e 12º. A mobilidade articular foi restabelecida em todos os pacientes operados. Onze pacientes apresentaram dor temporária no local da retirada do enxerto; no entanto, nenhum apresentou parestesia. A incidência de complicações foi de 8% (infecção, perda da correção, fratura articular. CONCLUSÃO: A técnica mostrou-se reprodutível, simples, biológica, precisa e com baixos custos, podendo ser uma alternativa às técnicas já existentes.OBJECTIVE: Roentgenographic assessment of lower limb alignment, in the frontal and sagittal planes, after a high tibial osteotomy. To stabilize the osteotomy, a tricortical iliac graft was used along with a positioning screw. METHODS

  19. Sildenafil vs. Nitroprussiato de Sódio durante Teste de Reatividade Pulmonar pré-transplante cardíaco Sildenafil vs. sodium before nitroprusside for the pulmonary hypertension reversibility test before cardiac transplantation

    Aguinaldo Figueiredo Freitas Jr

    2012-09-01

    Full Text Available FUNDAMENTO: A hipertensão pulmonar é associada ao pior prognóstico no pós-transplante cardíaco. O teste de reatividade pulmonar com Nitroprussiato de Sódio (NPS está associado a elevados índices de hipotensão arterial sistêmica, disfunção ventricular do enxerto transplantado e elevadas taxas de desqualificação para o transplante. OBJETIVO: Neste estudo, objetivou-se comparar os efeitos do Sildenafil (SIL e NPS sobre variáveis hemodinâmicas, neuro-hormonais e ecocardiográficas durante teste de reatividade pulmonar. MÉTODOS: Os pacientes foram submetidos, simultaneamente, ao cateterismo cardíaco direito, ao ecocardiograma e à dosagem de BNP e gasometria venosa, antes e após administração de NPS (1 - 2 µg/Kg/min ou SIL (100 mg, dose única. RESULTADOS: Ambos reduziram a hipertensão pulmonar, porém o nitrato promoveu hipotensão sistêmica significativa (Pressão Arterial Média - PAM: 85,2 vs. 69,8 mmHg, p BACKGROUND: Pulmonary hypertension is associated with a worse prognosis after cardiac transplantation. The pulmonary hypertension reversibility test with sodium nitroprusside (SNP is associated with a high rate of systemic arterial hypotension, ventricular dysfunction of the transplanted graft and high rates of disqualification from transplantation. OBJECTIVE: This study was aimed at comparing the effects of sildenafil (SIL and SNP on hemodynamic, neurohormonal and echocardiographic variables during the pulmonary reversibility test. METHODS: The patients underwent simultaneously right cardiac catheterization, echocardiography, BNP measurement, and venous blood gas analysis before and after receiving either SNP (1 - 2 µg/kg/min or SIL (100 mg, single dose. RESULTS: Both drugs reduced pulmonary hypertension, but SNP caused a significant systemic hypotension (mean blood pressure - MBP: 85.2 vs. 69.8 mm Hg; p < 0.001. Both drugs reduced cardiac dimensions and improved left cardiac function (SNP: 23.5 vs. 24.8%, p = 0

  20. Nível de ansiedade de clientes submetidos a cineangiocoronariografia e de seus acompanhantes Nivel de ansiedad de acompañantes y clientes durante el cateterismo cardíaco Caregivers and patient's anxiety level during cardiac catheterizathion

    Eliane da Silva Grazziano

    2004-04-01

    Full Text Available Este estudo exploratório e com abordagem quantitativa teve como objetivos identificar o nível de ansiedade de 40 acompanhantes e 40 clientes submetidos a cineangiocoronariografia pela primeira vez, no período de espera do exame, e correlacionar os dados entre si e com as variáveis sóciodemográficas, utilizando a Escala de Ansiedade-Estado (IDATE. Concluiu-se que a maioria dos clientes apresenta baixo nível de ansiedade e a maioria dos acompanhantes apresenta nível médio de ansiedade. Na análise das correlações, não houve relação entre o nível de ansiedade e as variáveis sóciodemográficas da população estudada. Na análise das comparações, observou-se que o acompanhante do sexo masculino é mais ansioso que aquele do sexo feminino. As intervenções de enfermagem, nesse período, podem ser mais eficazes se incluírem ações para redução da ansiedade dos familiares/acompanhantes.Este estudio exploratorio de carácter cuantitativo que tuvo como objetivo analizar el nivel de ansiedad de 40 acompañantes y 40 clientes sometidos por primera vez al cateterismo cardíaco y durante el periodo de espera del examen, con aplicación de la Escala de Ansiedad-Estado (IDATE. La conclusión es que la mayoría de los clientes tiene bajo nivel de ansiedad e sus acompañantes tienen nivel medio de ansiedad. Pudimos verificar en el análisis estadístico que no hay relación entre el nivel de ansiedad y la variables sociodemográficas de la población estudiada. El análisis de las comparaciones muestra que el acompañante del sexo masculino es más ansioso que el femenino. Intervenciones específicas de enfermería para reducir ansiedad del acompañante durante el cateterismo cardíaco podrán ayudar con la ansiedad de los clientes.This exploratory and quantitative study aimed to identify the anxiety level of 40 caregivers and 40 patients before cardiac catheterization and to establish a correlation among them and with sociodemographic

  1. QUINOA (CHENOPODIUM QUINOA WILLD: DIGESTIBILIDADE IN VITRO, DESENVOLVIMENTO E ANÁLISE SENSORIAL DE PREPARAÇÕES DESTINADAS A PACIENTES CELÍACOS

    L. I. A. CASTRO

    2008-11-01

    Full Text Available

    A quinoa (Chenopodium quinoa Willd é um pseudocereal isento de glúten, oriundo dos Andes, onde tem sido cultivado há milhares de anos. O objetivo deste trabalho foi desenvolver e avaliar sensorialmente algumas preparações contendo quinoa em grãos, flocos e farinha, destinadas ao paciente celíaco, e determinar a digestibilidade in vitro de sua proteína, submetida ou não ao tratamento térmico. As amostras foram avaliadas sensorialmente através de um teste de aceitação utilizando a escala hedônica nominal de 9 pontos. O método utilizado na análise da digestibilidade protéica in vitro foi o da queda de pH após 10 minutos, com a adição das enzimas tripsina e pancreatina às amostras de quinoa, tratadas e não tratadas termicamente. Das sete preparações testadas, seis foram bem aceitas, já que apresentaram um Índice de Aceitabilidade maior que 70%. Os flocos e grãos de quinoa, após serem testados termicamente, tiveram sua digestibilidade otimizada. Portanto, a quinoa e seus derivados podem ser considerados uma boa opção para a alimentação dos indivíduos portadores da doença celíaca.

  2. Validação do reprocessamento de cateteres cardíacos angiográficos: uma avaliação da funcionalidade e da integridade Validación del reprocesamiento de catéteres cardíacos angiográficos: una evaluación de la funcionalidad e integridad Reprocessing validation of angiographic cardiac catheters: an evaluation of the functionality and integrity

    Thabata Coaglio Lucas

    2010-12-01

    Full Text Available Objetivou-se validar o reprocessamento de cateteres cardíacos angiográficos quanto às suas características de funcionalidade mecânica e à integridade molecular e micro-estrutural da cadeia polimérica. Pesquisa experimental, aplicada, comparativa e controlada. Construiu-se uma bancada de simulação de uma arteriografia de coronária esquerda para simular um estresse mecânico e biológico em cateteres. Testou-se a funcionalidade por ensaio de tração e a integridade por Espectroscopia na Região do Infravermelho e Microscopia Eletrônica de Varredura. Evidenciou-se uma tendência ao aumento da rigidez a cada acréscimo do número de reprocessamento (pEl objetivo del trabajo fue validar el reprocesamiento de catéteres cardíacos angiográficos en cuanto a sus características de funcionalidad mecánica e integridad molecular y microestructural de la cadena de polímeros. Investigación experimental, aplicada, comparativa y controlada. Se construyó un banco de simulación de una arteriografía de coronaria izquierda para simular un estrés mecánico y biológico en catéteres. Se testeó la funcionalidad por ensayo de tracción y la integridad por Espectroscopía Local Infrarroja y Microscopía Electrónica de Barrido. Se evidenció una tendencia al aumento de la rigidez en cada incremento del número de reprocesamientos (pThe objective of this study was to validate the reprocessing of angiographic cardiac catheters regarding their characteristics of mechanical functionality and the molecular and micro-structural integrity of the polymeric chain. This is an experimental, applied, comparative and controlled study. A simulation set was built for a left coronary angiography in order to simulate mechanical and biological stress in the catheters. Traction tests were performed for the functionality and the integrity was tested through Infrared Spectrometry and Scanning Electronic Microscopy. The study evidenced a tendency to an increase in

  3. Avaliação da qualidade de vida e mortalidade em pacientes com eventos cardíacos graves no pós-operatório Evaluación de la calidad de vida y de la mortalidad en pacientes con eventos cardíacos mayores en el postoperatorio Quality of life and mortality assessment in patients with major cardiac events in the postoperative period

    Fernando José Abelha

    2010-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Complicações cardiovasculares no pós-operatório associam-se a elevadas mortalidade e morbidade. Poucos estudos avaliaram o grau de dependência desses doentes e a percepção da sua saúde. O objetivo deste trabalho foi avaliar a mortalidade e a qualidade de vida em doentes que desenvolveram eventos cardíacos graves (EC no pós-operatório. MÉTODO: Estudo retrospectivo numa Unidade de Tratamento Intensivo Cirúrgica (UTI-Cirúrgica, entre março de 2006 e março de 2008. Os doen tes foram avaliados quanto à ocorrência de EC. Seis meses após a alta, foi preenchido o questionário Short-Form-36 (SF-36 e avaliada a dependência nas atividades da vida diária (AVD. As comparações entre grupos independentes de doentes foram efetuadas com teste t de Student. A comparação entre cada variável e a ocorrência de EC foi efetuada por regressão logística envolvendo todos os doentes. RESULTADOS: Dos 1.280 doentes que apresentaram critérios de inclusão, 26 (2% desenvolveram EC. A análise univariada identificou como determinantes independentes para o desenvolvimento de EC: estado físico ASA, hipertensão arterial, doença cardíaca isquêmica, doença cardíaca congestiva e escore do Índice de Risco Cardíaco Revisado. A mortalidade seis meses após alta da UTI-Cirúrgica foi de 35%. Dos 17 sobreviventes aos seis meses, 13 completaram os questionários. Trinta e um por cento referiram que sua saúde em geral era melhor no dia em que responderam ao questionário do que 12 meses antes. Sessenta e nove por cento dos doentes estavam dependentes nas AVD instrumentais e 15%, nas AVD pessoais. CONCLUSÕES: O desenvolvimento de EC tem sério impacto no tempo de hospitalização e nas taxas de mortalidade. Seis meses após a alta da UTI-Cirúrgica, mais de metade dos doentes estavam dependentes em pelo menos uma AVD instrumental.JUSTIFICATIVA Y OBJETIVOS: Las complicaciones cardiovasculares en el postoperatorio est

  4. Respostas cardiorrespiratórias durante exercício em portadores de transplante cardíaco. Análise ergoespirométrica comparativa com indivíduos normais Cardiorespiratory response during exercise in heart transplant recipients comparated to normal healthy subjects

    Ana Fátima Salles; Japy Angelini Oliveira Fº; Turíbio Leite de Barros Neto; Dirceu Rodrigues Almeida; Antonio Carlos Camargo Carvalho; Yara Juliano; Ênio Buffolo; Eulógio Emílio Martinez Fº

    1998-01-01

    OBJETIVO: Avaliar as respostas cardiorrespiratórias dos portadores de transplante cardíaco (TxC). MÉTODOS: Submeteram-se a testes ergoespirométricos 9 portadores de TxC (GI), pareados por sexo, idade, peso e altura, com 9 indivíduos sedentários, aparentemente sadios (GII). Os pacientes eram do sexo masculino, com idade de 48±12 anos, com TFI (NYHA) após 23±21 meses TxC. Faziam uso regular de ciclosporina, azatioprina, prednisona, dipiridamol e anti-hipertensivos. Os testes foram limitados por...

  5. Uso de fluorescência em um método de dissector modificado para estimar o número de miócitos no tecido cardíaco

    Rômulo Dias Novaes

    2012-03-01

    Full Text Available FUNDAMENTO: Métodos convencionais de dissector atualmente requerem consideráveis custos financeiros, técnicos e operacionais para estimar o número de células, incluindo cardiomiócitos, em uma área de 3D. OBJETIVO: Usar a microscopia de fluorescência em um método de dissector modificado para determinar o número de miócitos no tecido cardíaco em condições normais e patológicas. MÉTODOS: O estudo empregou camundongos Wistar machos com quatro meses de idade e peso de 366,25 ± 88,21 g randomizados em grupos controles (GC, n = 8 e infectados (GI, n = 8. Os animais do GI foram inoculados com cepa Y de T. cruzi (300.000 tripomastigotas/50 g. Após oito semanas, os animais foram pesados e sacrificados. Os Ventrículos Esquerdos (VE foram removidos para análise estereológica da densidade numérica de cardiomiócitos (Nv [c] e o número total dessas células no VE (N [c]. Esses parâmetros foram estimados usando um dissector fluorescente (DF e comparados com os métodos convencionais de dissector óptico (DO e dissector físico (DFi. RESULTADOS: Em ambos os métodos de dissector, os animais do GI apresentaram queda significativa de Nv[c] e N[c] em comparação com os animais do GC (P > 0,05. Uma correlação forte, igual ou superior a 96%, foi obtida entre DF, DO e DFi. CONCLUSÃO: O método DF parece ser igualmente confiável para determinar Nv[c] e N[c] em condições normais e patológicas, apresentando algumas vantagens em relação aos métodos convencionais de dissector: redução de cortes histológicos e imagens na análise estereológica, redução do tempo de análise das imagens, a construção de DF em microscópios simples, utilizando o modo de epifluorescência, distinção de planos de dissector em ampliações inferiores.

  6. Sevoflurano e desflurano sobre o ritmo cardíaco de cães tratados com infusão contínua de doses crescentes de adrenalina

    Nunes Newton

    2004-01-01

    Full Text Available Os anestésicos inalatórios sensibilizam o miocárdio ou seu sistema de condução à ação das catecolaminas endógenas e/ou exógenas, predispondo o animal às arritmias cardíacas. Dentre os anestésicos voláteis, o sevoflurano e o desflurano são fármacos relativamente recentes e, embora sejam dotados de características relacionadas a não sensibilização do miocárdio às catecolaminas, desconhecem-se estudos que comparem suas eventuais propriedades antiarritmogênicas. Com o objetivo de estudar, comparativamente, o comportamento do ritmo cardíaco e observar eventuais bloqueios atrioventriculares em cães anestesiados pelo sevoflurano e desflurano e submetidos à infusão contínua de adrenalina, foram utilizados 20 animais adultos, os quais foram separados em dois grupos de igual número (G1 e G2. Aos cães do G1, foi administrado propofol, na dose média de 10mmg.kg-1; em seguida os animais receberam sevoflurano, a 1,5CAM. Decorridos 30 minutos do início da administração do anestésico volátil, iniciou-se a infusão de adrenalina na dose de 1mmg.kg-1.min-1. A cada 10 minutos, a dose da catecolamina foi acrescida em uma unidade, cessando-se a administração em 6mmg.kg-1.min-1. Para o G2, empregou-se a mesma metodologia, substituindo-se o sevoflurano pelo desflurano, administrado a 1,5CAM. A cada dose de adrenalina, foi feita contagem de batimentos ventriculares ectópicos, bem como a observação de bloqueios atrioventriculares. Os achados foram tratados pelos métodos estatísticos de Análise de Perfil e Kruskall-Wallis. Os resultados permitiram concluir que o desflurano minimiza de maneira mais eficiente a arritmia induzida pela adrenalina, além de reduzir a incidência de bloqueios atrioventriculares.

  7. Cardiac sympathetic-parasympathetic balance in rats with experimentally-induced acute chagasic myocarditis O balanço autonômico cardíaco nas ratas com miocardite chagásica aguda experimental

    Diego F. Davila

    1995-04-01

    Full Text Available To clarify the mechanism responsible for the transient sinus tachycardia in rats with acute chagasic myocarditis, we have examined the cardiac sympathetic-parasympathetic balance of 29 rats inoculated with 200,000 parasites (Trypanosoma cruzi. Sixteen infected animals and 8 controls were studied between days 18 and 21 after inoculation (acute stage. The remaining 13 infected animals and 9 controls were studied between days 60 and 70 after inoculation (sub-acute stage. Under anesthesia (urethane 1.25 g/kg, all animals received intravenous atenolol (5 mg/kg and atropine (10 mg/kg. Acute stage: The baseline heart rate of the infected animals was significantly higher than that of the controls (P Com a finalidade de pesquisar o mecanismo responsável pela taquicardia sinusal transitória que ocorre nas ratas com miocardite chagásica aguda, foi estudado o balanço autonômico cardíaco em 16 ratas inoculadas com Trypanosoma cruzi por via intraperitoneal. Oito animais foram estudados aos 18 e 21 dias após-inoculação (Estádio agudo; os oito animais restantes foram estudados entre os dias 60 a 70 após inoculação (Estádio sub-agudo. Todos os animais em estudo bem como os controles receberam atenolol e atropina. No estádio agudo, a frequência cardíaca basal dos animais infectados foi significativamente maior que a dos controles. A resposta cronotrópica negativa pela administração de atenolol foi quatro vezes maior nos animais infectados. No estádio sub-agudo, a frequência cardíaca basal e a resposta cronotrópica ao atenolol e atropina foi similar nos dois grupos do estudo. Os nossos resultados sugerem que no estádio agudo da miocardite chagásica experimental, a atividade simpática encontra-se periodicamente aumentada.

  8. Pressão expiratória positiva na via aérea por máscara facial na hemodinâmica de pós-operatórios cardíacos

    Ana Claudia Borges dos Santos Sena

    2010-10-01

    Full Text Available FUNDAMENTOS: A pressão expiratória positiva na via aérea por máscara facial (EPAP é utilizada no pós-operatório de cirurgias cardíacas, entretanto, seus efeitos hemodinâmicos não foram claramente estudados. OBJETIVO: Avaliar as alterações hemodinâmicas causadas pela EPAP em pacientes pós-cirurgia cardíaca monitorados por cateter de Swan-Ganz. MÉTODOS: Foram incluídos no estudo, pacientes no primeiro ou segundo pós-operatório de cirurgia cardíaca, estáveis hemodinamicamente e com cateter de Swan-Ganz. Eles foram avaliados em repouso e após o uso de 10 cmH2O de EPAP, de forma randomizada. As variáveis estudadas foram: saturação de oxigênio, frequências cardíaca e respiratória, pressões arteriais médias sistêmica e pulmonar (PAM e PAMP, pressões venosa central (PVC e de oclusão da atéria pulmonar (POAP, débito e índice cardíacos, e resistências vasculares sistêmica e pulmonar. Os pacientes foram divididos em subgrupos (com fração de ejeção 50% e os dados foram comparados por teste t e ANOVA. RESULTADOS: Vinte e oito pacientes foram estudados (22 homens, idade média 68 ± 11 anos. Comparando o período de repouso versus EPAP, as alterações observadas foram: POAP (11,9 ± 3,8 para 17,1 ± 4,9 mmHg, p < 0,001; PVC (8,7 ± 4,1 para 10,9 ± 4,3 mmHg, p = 0,014; PAMP (21,5 ± 4,2 para 26,5 ± 5,8 mmHg, p < 0,001; PAM (76 ± 10 para 80 ± 10 mmHg, p = 0,035. As demais variáveis não mostraram diferenças significativas. CONCLUSÃO: A EPAP foi bem tolerada nos pacientes e as alterações hemodinâmicas encontradas mostraram aumento nas medidas de pressão de enchimento ventricular direito e esquerdo, assim como, na pressão arterial média.

  9. Análise histomorfométrica dos cardiomiócitos e deposição de colágeno no músculo cardíaco de ratas ooforectomizadas

    Maria C.R. Silva

    2016-03-01

    Full Text Available Resumo: Esse estudo objetivou avaliar o efeito da ooforectomia sob os parâmetros histomorfométricos dos cardiomiócitos e quantificação de colágeno em ratas Wistar. Vinte ratas foram utilizadas e separadas em dois grupos: GI - ooforectomizada e GII - sham-ooforectomizada. Após a recuperação anestésica os animais foram acomodados em gaiolas e separados nas condições de ciclo claro/escuro 12/12h por um período de 6 meses. Passado o período experimental, os animais foram anestesiados, o coração retirado e mergulhado em formaldeído a 10%. Os fragmentos dos ventrículos foram submetidos ao processamento histológico e corados com hematoxilina e eosina. As análises histomorfométricas (área celular e área e volume nuclear foram realizadas pelo microscópio de luz e software ImageJ versão 1.44. Os dados foram submetidos à análise ANOVA e quando significantes, complementados pelo teste t de student (p<0,001. Observou-se uma diminuição significativa das áreas celular e nuclear dos cardiomiócitos do grupo GI quando comparado ao grupo GII, bem como a área ocupada, pelo colágeno, no músculo cardíaco foi maior em GI, quando comparado a GII. Diante disso, conclui-se que as alterações observadas nos cardiomiócitos do grupo GI, sugerem uma maior atividade apoptótica nesse grupo, devido à diminuição dos níveis séricos do estrógeno provocado pela ooforectomia e o aumento da área ocupada pelo colágeno, no grupo ooforectomizado, está associada ao efeito cardioprotetor do estrógeno.

  10. Avaliação da correlação entre o dióxido de carbono expirado e o débito cardíaco em pacientes submetidos à cirurgia cardíaca com circulação extracorpórea Evaluación de la correlación entre el dióxido de carbono expirado y el débito cardíaco en pacientes sometidos a la cirugía cardíaca con circulación extracorpórea Correlation between end-tidal carbon dioxide levels and cardiac output during cardiac surgery with cardiopulmonary bypass

    Karina Takesaki Miyaji; Roberto Iara Buscati; Antônio José Arraiz Rodriguez; Luciano Brandão Machado; Luiz Marcelo Sá Malbouisson; Maria José Carvalho Carmona

    2004-01-01

    JUSTIFICATIVA E OBJETIVOS: O CO2 expirado (P ET CO2) reflete, além da ventilação pulmonar (eliminação), a produção de dióxido de carbono (metabolismo) e o fluxo sangüíneo pulmonar (circulação). Quando o metabolismo e a ventilação são constantes, o CO2 expirado reflete o fluxo sangüíneo pulmonar e, desta forma, o débito cardíaco (DC). Este estudo tem como objetivo a avaliação da correlação entre o dióxido de carbono expirado (P ET CO2) e o débito cardíaco em pacientes submetidos à cirurgia car...

  11. AIDS na infância: acometimento cardíaco com e sem a terapia anti-retroviral tríplice combinada AIDS in childhood: cardiac involvement with and without triple combination antiretroviral therapy

    Maria do Carmo Soares Alves Cunha

    2008-01-01

    Full Text Available OBJETIVO: Descrever a prevalência de alterações cardíacas ao ecocardiograma em crianças com AIDS acompanhadas em serviço de referência aos 18±6 meses do diagnóstico confirmado de AIDS. MÉTODOS: Estudo transversal, com corte aos 18±6 meses do diagnóstico de AIDS. Incluídas 93 crianças com diagnóstico confirmado de AIDS por transmissão vertical, sem doença maligna, que, na avaliação cardiológica, realizaram ecocardiograma (eco. De forma exploratória avaliaram-se as alterações cardíacas nos pacientes sem uso (G1 e com uso (G2 de terapia combinada anti-retroviral. RESULTADOS: Quando do diagnóstico de AIDS, as crianças tinham em média 3,07 anos e 50,50% eram do sexo feminino. Esquema de terapia combinado com anti-retrovirais foi utilizado por 47 pacientes (G2. O acometimento cardíaco esteve presente em 40 crianças (43,00%. A presença de disfunção ventricular esquerda (G1:39,10%;G2:10,60% e o aumento isolado de ventrículo esquerdo (G1:6,60%;G2:14,90% foram os achados mais freqüentes. Observou-se associação significativa entre os grupos sem e com terapia anti-retroviral combinada quanto à presença de disfunção ventricular esquerda (RP=3,42; [1,41-8,26]; p =0,02 e de desnutrição (RP=1,79; [1,00-3,20]; p=0,04. CONCLUSÃO: O acometimento cardíaco foi freqüente nas crianças com AIDS, sendo a disfunção ventricular esquerda a alteração mais observada ao ecocardiograma. Houve diferença estatisticamente significativa entre os grupos com e sem tratamento tríplice combinado quanto à presença de disfunção ventricular esquerda e de desnutrição.OBJECTIVE: To describe the prevalence of cardiac abnormalities in the echocardiogram of children with AIDS followed up in a reference service at 18±6 months of AIDS confirmed diagnosis. METHODS: A cross-section study with a cohort after 18±6 months of AIDS diagnosis. The study included a total of 93 children with a confirmed diagnosis of AIDS with vertical

  12. Uso do óxido nítrico inalatório no tratamento da crise hipertensiva pulmonar no pós-operatório de transplante cardíaco

    Juan Alberto Cosquillo MEJIA

    2002-09-01

    Full Text Available OBJETIVO: Este trabalho relata a experiência no manuseio da crise hipertensiva pulmonar (CHP refratária, com o uso do óxido nítrico inalatório (NOi no pós-operatório imediato do transplante cardíaco (TC ortotópico. MÉTODOS: De outubro/1997 a fevereiro/2002 foram realizados 31 TC em adultos, sendo incluídos pacientes com RVP ±5,1horas.RESULTADOS: Cinco pacientes (1 mulher, com idade média de 42 anos, fizeram uso de NOi por apresentarem critérios de CHP, todos com sinais de baixo débito cardíaco. O tempo médio de CEC foi de 150,8±34,3 minutos, a média sistólica arterial pulmonar foi de 87mmHg (75-115 e a PO2 média de 60mmHg (FiO2 100%, sendo evidenciada dilatação moderada a severa do ventrículo direito no ETT. Foi administrado NOi durante uma média 35h (6-96, iniciando-se desmame após estabilização hemodinâmica. O tempo médio de ME do doador foi de 27,6±5,5horas, a internação hospitalar média foi de 63 dias (17-145, uma morte ocorreu por sepse no 17º PO e os demais pacientes estão em CF I (NYHA. CONCLUSÕES: O tempo de CEC superior a 120 minutos e tempo de ME do doador superior a 20 horas sugerem fatores de risco para CHP no período pós-operatório imediato do TC. O NOi é uma ferramenta útil no manuseio desta complicação, refratária ao tratamento convencional no POI de pacientes submetidos ao TC.OBJECTIVE: This study reviews our experience with the use of nitric oxide inhalation (NOi in the treatment of the refractory pulmonary hypertensive crisis (PHC during the immediate post-operative period (IPOP of heart transplantation (HT. METHOD: Between Oct/97 and Feb/02, 31 HT in adults were performed. Among them were patients with Pulmonary Vascular Resistance (PVR greater than 6 uW, or patients with PVR greater than 2,5 uW during the pharmacological test. All patients were weaned from the CPB (M=101±21 minutes in use of dobutamine, dopamine and milrinone. In the absence of an adequate response to these drugs

  13. Perfil clínico dos membros da associação dos celíacos do Brasil: regional de Santa Catarina (ACELBRA-SC Clinical profile of Santa Catarina members of Brazilian Celiac Association

    Clarissa Araujo Cassol

    2007-09-01

    Full Text Available RACIONAL: A doença celíaca é afecção inflamatória do intestino delgado associada à intolerância permanente ao glúten, que ocorre em indivíduos geneticamente susceptíveis. OBJETIVO: Conhecer as características clínicas e epidemiológicas dessa doença em nosso meio. MÉTODO: Tratou-se de estudo descritivo transversal com amostra não-probabilística selecionada entre os membros da Associação dos Celíacos do Brasil - Regional de Santa Catarina, aos quais foi enviado questionário abrangendo diversos aspectos da doença. RESULTADOS: Dos 506 associados, 145 (28,7% foram incluídos no estudo - todos celíacos confirmados por biopsia. Suas idades variaram entre 3,3 e 82,5 anos (média de 30,8 anos. A maioria era do sexo feminino (proporção de 2 mulheres para 1 homem. A idade média ao diagnóstico foi de 16 anos para os homens e 26,7 para as mulheres. Os principais sintomas relatados foram distensão abdominal (71,8%, dor abdominal (71% e diarréia (65,5%. No sexo masculino, predominaram diarréia e déficit ponderal enquanto que no sexo feminino aftas, constipação e anemia. Apenas 42,1% dos associados foram submetidos a biopsia em momento compatível com o diagnóstico correto de doença celíaca (44,2% relataram biopsia somente em vigência de dieta já isenta de glúten e 11,7% não souberam informar. Quanto aos testes sorológicos, 61,4% realizaram pelo menos um teste. Doenças associadas ou complicações foram relatadas por 65,5%; dessas, a mais freqüente foi a intolerância à lactose (33%. Suplementação vitamínica ou mineral foi indicada em 45% dos casos e 35,2% foram submetidos a densitometria óssea. Desses, 59% relataram um resultado alterado (osteopenia ou osteoporose. CONCLUSÕES: Os resultados apontam para uma tendência de diagnóstico da doença celíaca em idades mais avançadas em nosso meio, especialmente entre as mulheres, e sugerem a necessidade de maiores esclarecimentos do público em geral e da classe m

  14. ACO Agent Based Routing in AOMDV Environment

    Kaur Amanpreet

    2016-01-01

    Full Text Available Mobile Ad-hoc Network (MANET is a group of moving nodes which can communicate with each other without the help of any central stationary node. All the nodes in the MANET act as router for forwarding data packets. The nodes in the network also move randomly and there exists no fixed infrastructure. So, path breaks are the frequent problem in MANET. The routing protocol faces a lot of problem due these path breaks. Therefore, the routing protocol which is multipath in nature is more reliable than a unipath routing protocol. Ant colony optimization is a relatively new technique which is suitable for the optimization problems. AOMDV is a multipath routing protocol. Thus, if there happens to be path break, the packets can start following the new path which has already been selected. In this paper, we are trying to add ant’s agents into AOMDV behavior. In this way, the new protocol will be benefited by the dual properties i.e. of ant’s nature and multipath nature of AOMDV. The modified concept is simulated and the outcomes are compared with AOMDV, AODV and DSR routing protocols for few performance parameters. Results obtained are encouraging; the new algorithm performs better than traditional unipath and multipath routing protocols.

  15. Blind Alley Aware ACO Routing Algorithm

    Yoshikawa, Masaya; Otani, Kazuo

    2010-10-01

    The routing problem is applied to various engineering fields. Many researchers study this problem. In this paper, we propose a new routing algorithm which is based on Ant Colony Optimization. The proposed algorithm introduces the tabu search mechanism to escape the blind alley. Thus, the proposed algorithm enables to find the shortest route, even if the map data contains the blind alley. Experiments using map data prove the effectiveness in comparison with Dijkstra algorithm which is the most popular conventional routing algorithm.

  16. Consenso brasileiro de monitorização e suporte hemodinâmico - parte III: métodos alternativos de monitorização do débito cardíaco e da volemia Brazilian consensus of monitoring and hemodynamic support - part III: alternative methods for cardiac output monitoring and volemia estimation

    Guilherme Schettino

    2006-03-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A interpretação do débito cardíaco e da pré-carga como números absolutos não traz grandes informações sobre a hemodinâmica do paciente crítico. Em contrapartida, a monitorização da resposta do débito cardíaco à expansão volêmica ou suporte inotrópico é uma ferramenta muito útil na unidade de terapia intensiva, quando o paciente apresenta algum sinal de má perfusão tecidual. Apesar do CAP ser considerado como " padrão-ouro" na avaliação destes parâmetros, foram desenvolvidas tecnologias alternativas bastante confiáveis para a sua monitorização. MÉTODO: O processo de desenvolvimento de recomendações utilizou o método Delphi modificado para criar e quantificar o consenso entre os participantes. A AMIB determinou um coordenador para o consenso, o qual escolheu seis especialistas para comporem o comitê consultivo. Outros 18 peritos de diferentes regiões do país foram selecionados para completar o painel de 25 especialistas, médicos e enfermeiros. Um levantamento bibliográfico na MEDLINE de artigos na língua inglesa foi realizado no período de 1966 a 2004. RESULTADOS: Foram apresentadas recomendações referentes à análise da variação da pressão arterial durante ventilação mecânica, débito cardíaco contínuo por contorno de pulso arterial, débito cardíaco por diluição do lítio, Doppler transesofágico, bioimpedância transtorácica, ecocardiografia e reinalação parcial de gás carbônico. CONCLUSÕES: As novas e menos invasivas técnicas para medida do débito cardíaco, pré-carga e fluidoresponsividade apresentam adequada precisão e podem ser uma alternativa ao uso do CAP em pacientes graves.BACKGROUND AND OBJECTIVES: Cardiac output and preload as absolute data do not offer helpful information about the hemodynamic of critically ill patients. However, monitoring the response of these variables to volume challenge or inotropic drugs is a very useful tool in the

  17. Correlação entre gasometria atrial direita e índice cardíaco no pós-operatório de cirurgia cardíaca Correlation between right atrial venous blood gasometry and cardiac index in cardiac surgery postoperative period

    João Jackson Duarte

    2010-06-01

    Full Text Available OBJETIVO: Determinar a confiabilidade em se correlacionar o índice cardíaco com os dados fornecidos pela gasometria do sangue venoso atrial direito em pacientes submetidos à cirurgia cardíaca, durante o período pós-operatório. MÉTODOS: A partir das amostras de sangue arterial e venoso do átrio direito, colhidas no pós-operatório de cirurgia cardíaca, foram determinados os parâmetros de oxigênio do sangue venoso do átrio direito. Estes parâmetros foram então comparados com o índice cardíaco determinado pela termodiluição. RESULTADOS: Houve boa correlação entre a saturação de oxigênio do sangue venoso do átrio direito (SvO2, diferença artério-venosa do conteúdo de oxigênio do sangue colhido no átrio direito e o índice cardíaco aferido pela termodiluição, com boa sensibilidade e especificidade e alto valor preditivo positivo e negativo. A pressão do sangue do átrio direito (PvO2 apresentou baixa sensibilidade na estimativa de baixo débito cardíaco. CONCLUSÃO: No pós-operatório de cirurgia cardíaca, a SvO2e a diferença artério-venosa do conteúdo de oxigênio (C(avO2 apresentaram-se como parâmetros confiáveis correlacionados a baixo débito cardíaco. A PvO2 foi pouco sensível no diagnóstico de baixo débito no pós-operatório de cirurgia cardíaca.OBJECTIVE: To determine, even during postoperative period, the confiability of the cardiac index correlate with the data data given by a central atrial venous blood gasometry in patients who underwent cardiac surgery. METHODS: From the sample of arterial and venous blood of right atrium gathered in postoperative of cardiac surgery, it was determinated the hemoglobin concentration and the gasometric study through what was observed of the venous oxygen saturation (SvO2 and the partial pressure of oxygen from venous blood gathered in right atrium (PvO2, add to the calculation of artery-venous difference of the oxygen content - radial artery / right atrium (C

  18. Inibição da corrente de cálcio tipo L por tramadol e enantiômeros em miócitos cardíacos de ratos

    Emiliano Medei

    2011-10-01

    Full Text Available FUNDAMENTO: O tramadol é um analgésico de ação central cujo mecanismo de ação envolve a ativação de um receptor opioide. Anteriormente, mostramos que o tramadol e seus enantiômeros apresentavam um efeito inotrópico negativo sobre o músculo papilar no qual o (+-enantiômero era mais potente que (-- e (±-tramadol. OBJETIVO: No presente trabalho, investigamos os efeitos do tramadol e seus enantiômeros na corrente de cálcio tipo L (I Ca-L. MÉTODOS: Os experimentos foram realizados em miócitos ventriculares isolados de ratos Wistar utilizando a técnica de patch-clamp com configuração de célula inteira. RESULTADOS: O tramadol (200 µM reduziu a amplitude de pico do I Ca-L em potenciais de 0 a +50 mV. Em 0 mV, a I Ca-L foi reduzida em 33,7 ± 7,2%. (+- e (--tramadol (200 µM produziram uma inibição semelhante da I Ca-L, na qual a amplitude do pico foi reduzida em 64,4 ± 2,8% e 68,9 ± 5,8%, respectivamente a 0 mV (P > 0,05. O tramadol, (+- e (--tramadol mudaram a inativação de estado estacionário de I Ca-L para potenciais de membrana mais negativos. Além disso, tramadol e (+-tramadol alteraram significativamente a curva de recuperação dependente de tempo da I Ca-L para a direita e reduziram a recuperação de I Ca-L da inativação. A constante de tempo foi aumentada de 175,6 ± 18,6 a 305,0 ± 32,9 ms (P < 0,01 para o tramadol e de 248,1 ± 28,1 ms para 359,0 ± 23,8 ms (P < 0,05 para o (+-tramadol. O agonista do receptor µ-opioide (DAMGO não tem nenhum efeito na I Ca-L. CONCLUSÃO: A inibição da I Ca-L induzida por tramadol e seus enantiômeros não teve relação com a ativação de receptores opioides e poderia explicar, pelo menos em parte, seu efeito inotrópico negativo cardíaco.

  19. Intervenção coronária percutânea utilizando Full Metal Jacket com stents farmacológicos: eventos cardíacos adversos maiores em um ano

    Rita Calé

    2013-08-01

    Full Text Available FUNDAMENTO: O benefício clínico de intervenção coronária percutânea (ICP para lesões coronárias longas é incerto; além disso, foram levantadas dúvidas questões sobre a sua segurança. OBJETIVO: Avaliar os preditores de eventos cardíacos adversos maiores (ECAM associados à ICP utilizando Full Metal Jacket (FMJ, definido como a sobreposição de stents farmacológicos (SF medindo >60 mm de comprimento, para lesões muito longas. MÉTODOS: Foram incluídos 136 pacientes consecutivos com lesões coronárias longas, requerendo FMJ em nosso cadastro de centro único. O desfecho primário incluiu a ocorrência combinada de todas as causas de morte, infarto do miocárdio (IM e revascularização do vaso alvo (RVA. Variáveis demográficas, clínicas, angiográficas e de procedimento foram avaliadas por meio de análise de regressão de Cox para determinar os preditores independentes de desfecho. RESULTADOS: O comprimento médio do stent por lesão foi de 73,2 ± 12,3 mm e o diâmetro médio do vaso de referência foi de 2,9 ± 0,6 mm. O sucesso angiográfico foi de 96,3%. A ausência de ECAM foi de 94,9% em 30 dias e 85,3% em um ano. No acompanhamento de um ano, a taxa de mortalidade por todas as causas foi de 3,7% (1,5% por mortes cardíacas, a taxa de IM foi de 3,7%, e a incidência de trombose de stent (TS definitiva ou provável foi de 2,9%. O gênero feminino [risco relativo (RR, 4,40; intervalo de confiança de 95% (IC, 1,81-10,66, p = 0,001 e ICP de artéria coronária não direita (RR, 3,49; p = 0,006; IC 95%, 1,42-8,59 foram preditores independentes de ECAM em um ano. A ausência de eventos adversos em um ano foi maior em pacientes com angina estável submetidos à ICP (RR, 0,33; IC 95% 0,13-0,80, p = 0,014. CONCLUSÕES: A ICP utilizando FMJ com SF para lesões muito longas foi eficaz, mas associada a uma alta taxa de TS em acompanhamento de um ano. No entanto, a taxa de mortalidade cardíaca, IM não relacionado a procedimento, e

  20. Indirect calorimetry can be used to measure cardiac output in septic patients? A calorimetria indireta pode ser utilizada para medir o débito cardíaco em pacientes sépticos?

    Maria Auxiliadora Martins

    2008-01-01

    Full Text Available PURPOSE: The aim of this study was to compare two different cardiac output (CO monitoring systems based on the thermodilution principle (Thermo-CO and indirect calorimetry (Fick mixed-CO in septic patients. METHODS: Prospective study in septic patients admitted in an intensive care unit of a university hospital. Nineteen patients aged on average 45.4 ± 21.5 years were enrolled in the study. Four series of hourly measurements by the two techniques were carried out simultaneously. RESULTS: No significant differences were observed between Thermo-CO and Fick mixed-CO (7.0 ± 1.8 L.min-1 and 6.4 ± 1.7 L.min-1.. Parallel analysis of Fick mixed-CO and Fick atrial-CO was performed introducing a correction factor for the eight atrial samples in order to adjust the values of oxygen saturation obtained from atrial blood (Fick corrected atrial-CO to those obtained from mixed venous blood. No significant differences could be detected between Fick mixed-CO and Fick corrected atrial-CO. The correlation coefficients of Thermo CO/Fick mixed-CO and Fick mixed-CO/Fick corrected atrial-CO were 0.84 and 0.94, respectively. CONCLUSION: We observed that the agreement between the two methods was satisfactory on the basis of the decisions made for treatment. Indirect calorimetry is useful to measure CO in patients with septic shock.OBJETIVO: O objetivo deste estudo foi comparar as medidas do débito cardíaco (DC obtidas pela termodiluição (DC-termo e pela calorimetria indireta (DC-Fick misto em pacientes com choque séptico. MÉTODOS: Estudo prospectivo em pacientes sépticos internados em unidade de terapia intensiva de um hospital universitário. Foram estudados 19 pacientes (45,4 ± 21,5 anos. Foram realizadas quatro séries de medidas do DC pelos dois métodos, simultaneamente. RESULTADOS: Não houve diferenças significativas entre os valores do DC-termo e DC-Fick misto (7,0 ± 1,8 L.min-1 e 6,4 ± 1,7 L.min-1, respectivamente. Na avaliação dos oito casos

  1. Imunodepressão induzida por talidomida e ciclosporina em transplante cardíaco heterotópico de coelho Imunodeppression induced by thalidomide and cyclosporine in heterotopic heart transplantation of rabbits

    João Batista Vieira de Carvalho

    2003-04-01

    Full Text Available OBJETIVO: A talidomida, por seus efeitos antiinflamatórios e imunodepressores, tem sido utilizada no tratamento de doenças dermatológicas e na doença enxerto-contra-hospedeiro no transplante de medula óssea. O objetivo deste trabalho é avaliar a ação deste medicamento como imunodepressor em transplante de órgãos, estudando sua ação isoladamente ou em combinação com a ciclosporina na prevenção da rejeição ao aloenxerto cardíaco heterotópico em coelho. MÉTODO: Foram utilizados 50 coelhos, sendo 25 doadores e 25 receptores.Os animais receptores foram subdivididos em cinco grupos (n= 5 : Grupo I (controle animais não-imunodeprimidos; Grupo II (imunodeprimidos com ciclosporina na dose de 10 mg/kg/dia; Grupo III (imunodeprimidos com talidomida na dose de 100 mg/kg/dia; Grupo IV (imunodeprimidos com ciclosporina na dose de 5,0 mg/kg/dia e Grupo V (imunodeprimidos com ciclosporina na dose de 5,0 mg/kg/dia associada a talidomida na dose de 50 mg/kg/dia. Os medicamentos foram administrados através de cateter orogástrico, a partir do dia anterior ao transplante. RESULTADOS: O coração do doador foi implantado no abdome dos receptores. A associação de talidomida e ciclosporina apresentou o menor escore histopatológico de rejeição (p BACKGROUND: Because of its anti-inflammatory and immunodepressive effects, thalidomide has been used for the treatment of dermatologic diseases and of host-versus-graft disease in patients submitted to bone marrow transplantation. In the present study we evaluated the immunodepressive action of thalidomide alone or in combination with cyclosporine on the prevention of rejection of a heterotopic cardiac allograft in rabbits. METHODS: Fifty rabbits were used, 25 of them as donors and 25 as recipients. Recipient animals were divided into five groups (n = 5 each: Group I (control _ non-immunodepressed animals, Group II (immunodepressed animals with cyclosporine at the dose of 10 mg/kg/day, Group III

  2. Transplante cardíaco em Campo Grande - MS. Redução significativa de lesão coronária pós transplante: relato de caso

    Marcos Vinícius R. P. CALDAS

    1997-04-01

    Full Text Available No Serviço de Cirurgia Cardíaca da Santa Casa de Campo Grande/MS - foi realizado, em 23 de setembro de 1994, um transplante cardíaco ortotópico no paciente C.A.D., 27 anos, portador de miocardiopatia dilatada idiopática, o qual transcorreu sem anormalidades. O paciente recebeu alta da UTI com 7 dias e alta hospitalar no 40º dia de pós-operatório, recebendo ciclosporina, azatioprina e prednisona para manutenção do enxerto, captopril, furosemida e aspirina. Apresentou no 1º ano de seguimento 2 episódios de rejeição, leve e moderada, sendo modificada a posologia dos imunossupressores. Em setembro de 1995, nos exames de seguimento, foi detectada, na coronariografia, lesão obstrutiva de 50% em artéria coronária direita. Decidiu-se modificar a terapêutica do paciente, iniciando diltiazen substituindo o captopril, e associando-se complexo vitamínico (betacaroteno, C e E mais selênio, na tentativa de evitar progressão da lesão obstrutiva. Foi também realizada orientação dietética por nutricionista. Após 12 meses com a nova terapêutica, a coronariografia mostrou redução significativa da lesão obstrutiva em artéria coronária direita. Durante todo o período de seguimento o paciente apresentou níveis normais no lipidograma. Hoje o paciente encontra-se no terceiro ano de seguimento, assintomático e tendo suas atividades habituais sem intercorrências.The Cardiac Surgery Service of Campo Grande, Santa Casa/MS performed on September 23 rd, 1994 an orthotopic cardiac transplantation in a 27 year-old man with idiopathic dilated cardiomyopathy, which elapsed without abnormalities. The patient left the ICU in 7 days and was discharged at 40 th postoperative day, receiving cyclosporine, azathioprine and prednisone for graft support; captopril, furosemide and aspirin. Presented at one year follow-up, 2 rejection episodes, mil and moderate, when the immunesupressivet herapy dose was modified. On September 1995, at follow up, an

  3. Correlação entre classe funcional e qualidade de vida em usuários de marcapasso cardíaco Correlation between functional class and quality of life among cardiac pacemaker users

    TMB Cunha

    2007-10-01

    Full Text Available INTRODUÇÃO: Os crescentes avanços tecnológicos desenvolvidos para o tratamento de distúrbios de condução cardíaca vêm proporcionando aos pacientes melhores condições de vida. As escalas de classificação funcional e questionários de qualidade de vida (QV constituem uma forma suplementar de avaliação dos aspectos físicos, emocionais e funcionais dos pacientes. Entretanto, permanece a seguinte questão: existe correlação entre a classe funcional (CF e a percepção da QV em usuários de marcapasso (MP? OBJETIVO: O objetivo do estudo foi avaliar se existe correlação entre classe funcional (CF e QV em portadores de MP cardíaco definitivo. MÉTODOS: Foram avaliados 14 usuários de MP. Para avaliar CF, foi utilizada a escala de atividade específica proposta por Goldman, e, com objetivo de avaliação da QV, foi aplicado o questionário Aquarel associado ao SF-36. Com o objetivo de verificar se existe correlação entre as variáveis, foi aplicado o teste de correlação de Spearman, considerando como significativo aINTRODUCTION: Growing technological progress in treating patients with heart conduction disturbances has provided such patients with better life conditions. Functional classification (FC scales and quality of life (QOL questionnaires are additional means for evaluating patients' physical, emotional and functional characteristics. However, the question remains as to whether there is any association between FC and perception of QOL among pacemaker users. OBJECTIVE: To evaluate whether there is any correlation between FC and QOL among definitive cardiac pacemaker users. METHOD: Fourteen pacemaker users were evaluated. To assess FC, the specific activity scale proposed by Goldman was used. To evaluate QOL, the Aquarel questionnaire was used in association with SF-36. The Spearman correlation test was applied to investigate whether there was any association between the variables, considering p< 0.05 to be significant. The

  4. Variáveis perioperatórias de função ventilatória e capacidade física em indivíduos submetidos a transplante cardíaco Perioperative variables of ventilatory function and physical capacity in heart transplant patients

    Christian Correa Coronel

    2010-06-01

    Full Text Available INTRODUÇÃO: O transplante cardíaco é atualmente a única alternativa cirúrgica amplamente aceita para tratar pacientes com insuficiência cardíaca (IC grave que a terapia medicamentosa otimizada não consiga manter qualidade de vida adequada. OBJETIVO: Descrever e comparar os valores entre pré e pós-operatório, das capacidades física e pulmonar de pacientes que realizaram transplante cardíaco. MÉTODOS: Estudo de coorte retrospectivo composto por indivíduos submetidos ao transplante cardíaco, entre janeiro de 2001 a março de 2005, no IC-FUC/RS. RESULTADOS: Foram incluídos na análise 21 indivíduos. Observou-se redução dos valores de volumes e capacidades pulmonares (VEF1 e CVF no 1º dia de pós-operatório em relação ao pré-operatório (PINTRODUCTION: Heart transplantation is currently the only widely accepted surgical alternative to treat patients with severe heart failure (HF drug therapy cannot maintain optimal quality of life appropriate. OBJECTIVE: To describe and to compare the values between pre-and postoperative physical capacity and pulmonary patients who underwent heart transplantation. METHODS: A retrospective cohort composed of patients undergoing heart transplantation between January 2001 to March 2005 in IC-FUC/RS. RESULTS: Were included in the 21 individuals. We observed decreased levels of volume and lung capacity (FEV1 and FVC in the first days after surgery compared to preoperatively (P <0.001 and recovery of these values in the 14th postoperative day (P <0.001. The values of muscle strength showed similar trends in reducing post-operative period compared to preoperative (P <0.001 and recovered on the 14th postoperative day (P <0.001. A useful functional capacity, measured by testing 6-minute walk test (T6' showed improvement in the 14th postoperative day in relation to pre-operatively (P <0.001. CONCLUSION: Changes in ventilatory function of subjects undergoing cardiac transplantation are predictable, but

  5. Assistência de enfermagem a idosos que realizam cateterismo cardíaco: uma proposta a partir do modelo de adaptação de Calista Roy Asistencia de enfermería a ancianos que realizan cateterismo cardíaco: una propuesta a partir del modelo de adaptación de Calista Roy Nursing care to elderly patients undergoing heart catheterization: a proposal according to the Adaptation model of Calista Roy

    Maria Célia de Freitas

    2006-10-01

    Full Text Available O estudo objetivou identificar os diagnósticos de enfermagem de idosos que realizam cateterismo cardíaco, abordando os aspectos psicossociais, segundo a Teoria de Adaptação de Roy. Desenvolveu-se em hospital de pronto-atendimento em cardiologia de Fortaleza-CE, de janeiro a julho de 2005. Utilizou-se entrevista semi-estruturada, com 18 idosos de ambos os sexos, no pré-cateterismo. Na análise reconheceram-se os diagnósticos: alteração na manutenção da saúde, ansiedade, medo e alteração no processo familiar. Como intervenções propõe-se: criar um clima de confiança, antes do exame; escutar e respeitar sentimentos, crenças e valores, orientar quanto ao procedimento. A utilização desta teoria permitiu reconhecer que as pessoas, mediante estímulos, podem desencadear respostas positivas ou negativas, cabendo ao enfermeiro atuar como mediador.El estúdio objetivó identificar los diagnósticos de enfermería abordando los aspectos psico-sociales de los pacientes que realizan cateterismo cardiaco, según la Teoría de Adaptación de Roy. Se desarrolló en la sección de cardiología de un hospital de Fortaleza-CE, de Janeiro a Julio de 2005. Se utilizó la entrevista semi-estructurada, con 18 ancianos, en el pre-cateterismo. En el análisis reconocieron los diagnósticos: alteración en la manutención de la salud, ansiedad, miedo y alteración en el proceso familiar. Entre las acciones se elaboraron las siguientes: crearse un clima de confianza para el paciente después del examen; escuchar y respetar sentimientos, creencias y valores referentes a la situación; orientar el paciente cuanto al procedimiento. La utilización de esta teoría permitió reconocer que las personas, mediante estímulos, pueden desencadenar respuestas ora positivas ora negativas, cabiendo al enfermero actuar como mediador.The study aimed at identifying the nursing diagnoses related to the psychological and social aspects of elderly patients undergoing

  6. Uso de fluorescência em um método de dissector modificado para estimar o número de miócitos no tecido cardíaco Uso de fluorescencia en un método de disector modificado para estimar el número de miocitos en el tejido cardíaco Use of fluorescence in a modified disector method to estimate the number of myocytes in cardiac tissue

    Rômulo Dias Novaes

    2012-03-01

    Full Text Available FUNDAMENTO: Métodos convencionais de dissector atualmente requerem consideráveis custos financeiros, técnicos e operacionais para estimar o número de células, incluindo cardiomiócitos, em uma área de 3D. OBJETIVO: Usar a microscopia de fluorescência em um método de dissector modificado para determinar o número de miócitos no tecido cardíaco em condições normais e patológicas. MÉTODOS: O estudo empregou camundongos Wistar machos com quatro meses de idade e peso de 366,25 ± 88,21 g randomizados em grupos controles (GC, n = 8 e infectados (GI, n = 8. Os animais do GI foram inoculados com cepa Y de T. cruzi (300.000 tripomastigotas/50 g. Após oito semanas, os animais foram pesados e sacrificados. Os Ventrículos Esquerdos (VE foram removidos para análise estereológica da densidade numérica de cardiomiócitos (Nv [c] e o número total dessas células no VE (N [c]. Esses parâmetros foram estimados usando um dissector fluorescente (DF e comparados com os métodos convencionais de dissector óptico (DO e dissector físico (DFi. RESULTADOS: Em ambos os métodos de dissector, os animais do GI apresentaram queda significativa de Nv[c] e N[c] em comparação com os animais do GC (P > 0,05. Uma correlação forte, igual ou superior a 96%, foi obtida entre DF, DO e DFi. CONCLUSÃO: O método DF parece ser igualmente confiável para determinar Nv[c] e N[c] em condições normais e patológicas, apresentando algumas vantagens em relação aos métodos convencionais de dissector: redução de cortes histológicos e imagens na análise estereológica, redução do tempo de análise das imagens, a construção de DF em microscópios simples, utilizando o modo de epifluorescência, distinção de planos de dissector em ampliações inferiores.FUNDAMENTO: Métodos convencionales de disector actualmente requieren considerables costos financieros, técnicos y operativos para estimar el número de células, incluyendo cardiomiocitos, en un

  7. Associação independente do tabagismo aos eventos cardíacos pós-operatórios e à mortalidade em 30 dias Asociación independiente del tabaquismo a los eventos cardiacos postoperatorios y a la mortalidad a 30 días Independent association of smoking with postoperative cardiac events and thirty-day mortality

    Luciane Midory Sakuma; Fabio Santana Machado; Milton Arruda Martins

    2010-01-01

    FUNDAMENTO: Há poucos estudos que demonstrem a associação do tabagismo, como fator de risco independente, aos eventos cardíacos pós-operatórios. OBJETIVO: Avaliar a associação do tabagismo, como variável independente, às complicações cardiovasculares pós-operatórias e à mortalidade em 30 dias em operações não cardíacas. MÉTODOS: Utilizou-se coorte retrospectiva de um hospital geral, na qual foram incluídos 1.072 pacientes estratificados em tabagistas atuais (n = 265), ex-tabagistas (n = 335) ...

  8. Pressão pulmonar aferida pela ecocardiografia em pacientes chagásicos indicados para transplante cardíaco Pulmonary pressure by echocardiophy in chagasic patients on heart transplant waiting list

    Cláudio Léo Gelape

    2011-03-01

    Full Text Available INTRODUÇÃO: O paciente com insuficiência cardíaca desenvolve aumento da pressão pulmonar por mecanismo retrógrado e a hipertensão arterial pulmonar (HP é um marcador de mau prognóstico. OBJETIVO: Correlacionar pressão pulmonar ao ecogardiograma (eco e ao cateterismo, em pacientes em lista de espera para transplante cardíaco (TC, especialmente nos chagásicos. MÉTODOS: Avaliamos 90 pacientes no HC-UFMG entre 2004 e 2009. Todos realizaram cateterismo e eco no pré-transplante. A idade média foi de 45,5 anos, sendo 68(75,6% homens, 42(46,7% chagásicos, 32(35,6% portadores de miocardiopatia dilatada e 10(11,1% isquêmicos. RESULTADOS: A eco-PSAP (pressão sistólica arterial pulmonar média foi de 45 ± 12mmHg. A cat-PSAP média foi de 47 ± 14mmHg. A eco-PSAP-chagásicos foi 41,7 ±12,5 mmHg e não-chagásicos, 47,6 ±12,8 mmHg P=0,04. A cat-PSAP-chagásicos foi de 46 ±12,1 mmHg e não-chagásicos 48,7±12,8mmHg; P=0,43. Oito pacientes apresentavam cat-PSAP>60. A correlação entre a eco-PSAP e o cat-PSAP nos chagásicos foi r=0,45, P=0,008 e nos não-chagásicos de r=0,66, P32,5mmHg tem uma sensibilidade de 79% e especificidade de 75% para diagnosticar HP, com área sob a curva ROC de 0,819. A eco-PSAP-não chagásico>35,5 mmHg tem sensibilidade de 82% e especificidade de 70% para HP, com área sob a curva ROC de 0,776. CONCLUSÕES: Há boa correlação entre a eco-PSAP e a cat-PSAP (r=0,54 entre os pacientes em fila de espera. A eco-PSAP foi menor no grupo dos chagásicos. O ecocardiograma é um método útil para diagnosticar e monitorar a pressão pulmonar previamente ao TC, especialmente em pacientes chagásicos. Entretanto, não é possível prescindirmos do cateterismo para avaliar a reatividade pulmonar com o teste com vasodilatador e indicar com segurança o TC mesmo nos pacientes chagásicos.INTRODUCTION: The patients suffering heart failure develop an increase in pulmonary pressure because of a retrograde mechanism. The

  9. Comparação dos valores de débito cardíaco obtidos por termodiluição e dopplerfluxometria transesofágica Comparison between two methods for hemodynamic measurement: thermodilution and oesophageal doppler

    Roberto Manara Victorio Ferreira

    2007-08-01

    Full Text Available OBJETIVO: A termodiluição (TD é padrão de monitorização hemodinâmica. Alguns par��metros hemodinâmicos podem ser medidos através do Doppler Transesofágico (DTE. Método simples, menos invasivo. Com o objetivo de avaliar a acurácia do DTE foram comparados TD e DTE na determinação de medidas de débito cardíaco (DC. MÉTODOS: Foram determinadas 192 medidas simultâneas, em diferentes situações clínicas em dez pacientes com idade entre 21 85 anos (cinco do gênero masculino e cinco do feminino, oito internados sépticos em uso de drogas vasoativas e dois monitorizados para laringectomia e transplante hepático; todas avaliadas ao longo de quatro horas, em intervalos de 30 minutos. Foram utilizados dois tipos de doppler: o DeltexR, e o ArrowR, introduzidos entre 35 e 45 cm da fossa nasal e localizados no ponto de maior diâmetro da aorta descendente. Na TD, foi utilizado cateter de artéria pulmonar (Swan Ganz BaxterR e monitor DX-2001R, confirmado o posicionamento radiologicamente e através das curvas pressóricas geradas. As medidas do DC realizadas através da TD foram obtidas com soro fisiológico gelado, sendo considerada a média de quatro medidas não diferentes de 5%. Foi aplicado o método estatístico de Bland e Altman, com utilização de gráfico de regressão linear. RESULTADOS: Não houve diferença estatisticamente significante entre esses dois métodos de medida hemodinâmica, com coeficiente de correlação de 0,88 para o DC (Doppler DeltexR X Swan Ganz BaxterR e coeficiente de correlação de 0,99 DC (Doppler Arrow rR X Swan Ganz BaxterR respectivamente, observando-se correlação. CONCLUSÃO: A medida das variáveis hemodinâmicas ao DTE foi obtida com facilidade nos dez pacientes estudados e revelou ter este dispositivo acurácia compatível à TD.OBJECTIVES: Thermodilution (TD is the "gold standard method" for hemodynamic monitoring. Some parameters can be measured by Oesophageal Doppler (OD, which is

  10. Validação de conteúdo das atuais e de novas características definidoras do diagnóstico de enfermagem débito cardíaco diminuído Validación de contenido de las actuales y nuevas características que definen el diagnostico de enfermería: disminución del gasto cardíaco Content validation of current and new defining characteristics of the nursing diagnosis: decreased cardiac output

    Juliana de Lima Lopes

    2010-01-01

    Full Text Available OBJETIVO: Validar o conteúdo das características definidoras, tanto aquelas atualmente aprovadas como as identificadas por meio de revisão de literatura, para o diagnóstico de enfermagem Débito Cardíaco Diminuído. MÉTODOS: Trata-se de um estudo de validação de conteúdo utilizando o modelo proposto por Fehring. As características definidoras foram validadas por 18 peritos (oito enfermeiros e dez médicos, usando uma escala do tipo Likert de cinco pontos e seguindo a classificação: escore maior do que 0,80 foram consideradas como as características principais, as com peso entre 0,50 a 0,79 como secundárias e as com média menor ou igual a 0,50, como irrelevantes. RESULTADOS: Dentre as 79 características definidoras investigadas, 38 (48,1% foram validadas, dentre elas, 17 presentes na NANDA-I e, 41 (51,9% foram consideradas como irrelevantes para este diagnóstico, sendo que oito estão listadas na NANDA-I. CONCLUSÃO: As características definidoras listadas atualmente na classificação da Taxonomia da NANDA-I não abrangem completamente o diagnóstico de enfermagem débito cardíaco diminuído.OBJETIVO: Validar el contenido de las características definidoras, tanto de las actualmente aprobadas como las identificadas por medio de una revisión de la literatura, para el diagnóstico de enfermería: disminución del gasto cardíaco. MÉTODOS: Se trata de un estudio de validación de contenido utilizando el modelo propuesto por Fehring. Las características definidoras fueron validadas por 18 expertos (ocho enfermeros y diez médicos, usando una escala de tipo Likert de cinco puntos y siguiendo la siguiente clasificación: las con puntaje mayor que 0,80 fueron consideradas como características principales; las con peso entre 0,50 y 0,79 como secundarias; y, las con promedio menor o igual a 0,50, como irrelevantes. RESULTADOS: Entre las 79 características definidoras investigadas, 38 (48,1% fueron validadas, entre ellas, 17 se

  11. Inventory of Ammonia Emissions from Livestock Production in Los Lagos and Los Ríos Regions, Chile Inventario de Emisiones de Amoníaco de la Producción Pecuaria de las Regiones de Los Lagos y de Los Ríos, Chile

    Josué Martínez-Lagos

    2010-03-01

    Full Text Available This paper presents the first inventory of ammonia emissions from livestock production in Los Lagos and Los Ríos Regions of Chile. The inventory was focused in this area because is where cattle production is concentrated. This study aimed to quantify the amount of N losses due to ammonia volatilization from livestock production in these regions of the country, and to provide its spatial representation identifying their main sources. Calculations have been carried out for 1997 and 2007, and also projections to 2017 and 2027 were obtained. Calculated emissions were 6097 and 6206 t NH3-N for 1997 and 2007, respectively. Major sources of NH3-N emissions were cattle accounting for more than 85%, followed by horses and pigs. Farm management practices as grazing, housing, manure storage and land spreading of manure accounted for 87%, 9%, 3%, and 2%, respectively, of total annual emissions. Projections suggest that emissions could increase up to 6344 and 6516 t NH3-N for 2017 and 2027, respectively. Emissions are much lower than those reported for developed European countries. However, intensification of cattle production systems may lead to an increase of ammonia emissions which could impact the temperate forest of Southern Chile characterized by low nutrient fluxes.Este artículo presenta el primer inventario de emisiones de amoníaco de la producción pecuaria de las Regiones de Los Lagos y Los Ríos de Chile, porque esta área concentra la producción chilena de ganado bovino. Este estudio tuvo como objetivos cuantificar las pérdidas de N por volatilización de amoníaco emitidas desde la producción animal en estas regiones del país, y proveer su representación espacial identificando las principales fuentes de emisión. Los cálculos fueron realizados para 1997 y 2007; y desde el año base se proyectaron emisiones para los años 2017 y 2027. Las emisiones calculadas fueron 6097 y 6206 t NH3-N para 1997 y 2007, respectivamente. Las principales

  12. Efeitos da suplementação do 17beta-estradiol no dano oxidativo cardíaco de ratas submetidas à privação dos hormônios ovarianos Effects of 17beta-estradiol replacement on cardiac oxidative damage in rats submitted to ovarian hormone deprivation

    Sônia Maria Rolim Rosa Lima

    2007-01-01

    Full Text Available OBJETIVO: avaliar o estresse oxidativo em tecido cardíaco de ratas ooforectomizadas, com ou sem terapia hormonal. MÉTODOS: ratas Wistar foram divididas em três grupos: grupo controle (GC, grupo ooforectomizada (GO e grupo ooforectomizada + suplementação hormonal (GOS. A privação estrogênica foi obtida pela ooforectomia bilateral. Uma semana após a ooforectomia, um pellet de 1,5 mg de 17beta-estradiol foi implantado nos animais do grupo GOS. Nove semanas após a ooforectomia, o tecido cardíaco foi obtido para a análise do estresse oxidativo por meio da medida da quimiluminescência e da atividade das enzimas antioxidantes catalase (CAT, superóxido dismutase (SOD e glutationa peroxidase (GPx. RESULTADOS: a quimiluminescência estava aumentada no GO (7348±312 cps/mg proteína quando comparado ao GC (6250±41 cps/mg proteína, pPURPOSE: to evaluate oxidative stress in cardiac tissue of ovariectomized rats, with and without hormonal therapy. METHODS: female Wistar rats were divided in three groups: control group (CG; ovariectomized group (OG; ovariectomized group with estrogen supplementation (ESG. The estrogen deprivation was done through bilateral ovariectomy. After one week from the ovariectomy, a pellet of 1.5 mg of 17beta-estradiol was implanted in the ESG animals. Nine weeks after the ovariectomy, cardiac tissue was obtained for the analysis of the oxidative stress through CL (chemiluminescence, and measurement of antioxidant enzymes catalase (CAT, superoxide dismutase (SOD and gluthatione peroxidase (GPx. RESULTS: CL was increased in the OG (7348±312 cps/mg protein when compared with the CG (6250±41 cps/mg protein, p<0.01, but there was no significant difference between the CG and the ESG (6170±237 cps/mg protein. Ovariectomy reduced SOD (35%, p<0.05 and CAT (22%, p<0.001 activities in the OG as compared with the CG. Hormonal therapy normalized antioxidant enzymes activities in the ESG. There was no statistically significant

  13. Importância da toxicidade pulmonar pela amiodarona no diagnóstico diferencial de paciente com dispnéia em fila para transplante cardíaco The importance of amiodarone pulmonary toxicity in the differential diagnosis of a patient with dyspnea awaiting a heart transplant

    Christiano Pereira Silva

    2006-09-01

    Full Text Available A amiodarona é um antiarrítmico da classe III, amplamente utilizado em arritmias ventriculares¹. Farmacologicamente é classificado como uma drogra ampifílica catiônica, pelos seus constituintes polares e apolares. Nos últimos anos, a amiodarona obteve destaque pelo seu uso em portadores de disfunção ventricular por qualquer etiologia, em especial a chagásica, quando ocorrem arritmias ventriculares². Entretanto, a despeito de seus benefícios hemodinâmicos e eletrofisiológicos, a amiodarona produz efeitos colaterais relevantes, como coloração azulada da pele, fotossensibilidade, disfunção tireoidiana, depósito corneal, neuropatia periférica, supressão da medula óssea, hepatite, bloqueios cardíacos, pneumonites e outros³. Este relato de caso se propõe a abordar uma de suas mais sérias complicações, a toxicidade pulmonar, aqui especialmente descrita como diagnóstico diferencial em um paciente chagásico que aguardava em fila de transplante cardíaco. Pneumonite por amiodarona constitui-se em um importante diagnóstico diferencial entre os pacientes que se apresentam na sala de emergência com dispnéia, quando estes são portadores de insuficiência cardíaca (IC e estão em uso dessa droga.Amiodarone is a class III antiarrhythmic medication used extensively to treat ventricular arrhythmias¹. It is pharmacologically classified as a cationic amphiphilic drug due to its polar and apolar components. During the past few years, amiodarone has proved to be an effective treatment therapy for patients with ventricular dysfunctions, regardless of the etiology, and in particular ventricular arrhythmia associated with Chagas disease². Nevertheless, despite its hemodynamic and electrophysiological benefits, amiodarone produces serious collateral effects such as a bluish skin discoloration, photosensitivity, thyroid dysfunction, corneal deposit, peripheral neuropathy, bone marrow suppression, hepatitis, heart blocks, pneumonitis

  14. Perfil clínico de pacientes chagásicos e não-chagásicos portadores de marca-passo cardíaco artificial Clinical profile of Chagas and non-Chagas' disease patients with cardiac pacemaker

    Leonor Garcia Rincon

    2006-06-01

    Full Text Available O objetivo do estudo foi comparar pacientes chagásicos e não-chagásicos com marca-passo cardíaco artificial uni ou bicameral quanto à fração de ejeção do ventrículo esquerdo, o limiar de estimulação ventricular e a incidência de arritmias cardíacas. Entre janeiro/2001 e novembro/2002 foram avaliados 45 pacientes chagásicos e 35 não-chagásicos portadores de marca-passo quanto à história clínica, radiografia do tórax, ecocardiograma, Holter 24h e análise telemétrica do marca-passo. Embora os chagásicos fossem mais jovens, os dois grupos foram semelhantes quanto a variáveis radiológicas e o limiar de estimulação ventricular direito. Os chagásicos apresentaram menor fração de ejeção do ventrículo esquerdo ao ecocardiograma e maior incidência de arritmia ventricular ao Holter 24h. Observou-se correlação positiva entre a baixa fração de ejeção do ventrículo esquerdo e a intensidade da arritmia ventricular ao Holter 24h. Em pacientes com marca-passo, a doença de Chagas está associada a marcadores cardíacos de prognóstico adverso.The aim of this study was to compare Chagas and non-Chagas' disease patients using single or dual-chamber pacemaker in relation to the ejection fraction of the left ventricle, the ventricular stimulation threshold and the occurrence of ventricular arrhythmia. From January, 2001 to November, 2002, 45 Chagas' disease patients and 35 non-Chagas' disease patients, all pacemaker users, were evaluated considering clinical history, echocardiographic study, Holter monitoring and analysis of the pacemaker telemetry data. Chagas' disease patients were significantly younger, but both groups were similar when chest X-Ray variables and right ventricular stimulation threshold were analyzed. Chagas' disease patients had a lower left ventricular ejection fraction and more frequent ventricular arrhythmia during Holter monitoring. A positive correlation between the low ejection fraction of the left

  15. Transplante cardíaco: complicações apresentadas por pacientes durante a internação Trasplante de corazón: complicaciones que presentan los pacientes durante la hospitalización Heart Transplantation: complications presented by patients during the hospitalization

    Elaine Araújo da Silva

    2012-12-01

    Full Text Available Com o avanço da ciência, a insuficiência cardíaca tem como possibilidade de intervenção o transplante cardíaco. Este trabalho teve como objetivos traçar o perfil demográfico dos pacientes submetidos ao transplante cardíaco e identificar as complicações apresentadas durante a internação. Trata-se de um estudo descritivo, quantitativo, realizado com 44 prontuários de pacientes submetidos a transplante de junho/2006 a julho/2009 em um Hospital Universitário de Belo Horizonte, Minas Gerais, Brasil. O projeto atendeu às recomendações da Resolução 196/96. Pelos resultados, a maioria dos pacientes era do sexo masculino, casada, escolaridade de nível fundamental e idade média de 45,2 anos. A miocardiopatia chagásica foi a principal causa de insuficiência cardíaca. As complicações predominantes foram alteração da glicemia, insuficiência renal e infecções. A taxa de mortalidade na internação foi de 20,4%. Além das complicações biológicas só foram registradas ansiedade e depressão. São necessárias pesquisas sobre o tema nos âmbitos psicossociais e espirituais, contribuindo para o desenvolvimento científico.Hoy día, con los avances de la medicina y de la tecnología para el tratamiento de la insuficiencia cardiaca irreversible, se ha utilizado como última intervención el trasplante cardíaco. Este trabajo se desarrolló con los objetivos de delinear el perfil demográfico de los pacientes sometidos a trasplante cardíaco e identificar las complicaciones presentadas por ellos después del trasplante de corazón. Estudio descriptivo y cuantitativo, realizado en conjunto con los registros de 44 pacientes sometidos a trasplante de corazón desde Jun/2006 hasta Jul/2009, en un Hospital Universitario de Belo Horizonte, Minas Gerais, Brasil. El proyecto cumplió con las recomendaciones de la Resolución 196/96. Los resultados mostraron que la mayoría de los pacientes eran del sexo masculino, casados, con educaci

  16. Avaliação da correlação entre o dióxido de carbono expirado e o débito cardíaco em pacientes submetidos à cirurgia cardíaca com circulação extracorpórea Evaluación de la correlación entre el dióxido de carbono expirado y el débito cardíaco en pacientes sometidos a la cirugía cardíaca con circulación extracorpórea Correlation between end-tidal carbon dioxide levels and cardiac output during cardiac surgery with cardiopulmonary bypass

    Karina Takesaki Miyaji

    2004-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O CO2 expirado (P ET CO2 reflete, além da ventilação pulmonar (eliminação, a produção de dióxido de carbono (metabolismo e o fluxo sangüíneo pulmonar (circulação. Quando o metabolismo e a ventilação são constantes, o CO2 expirado reflete o fluxo sangüíneo pulmonar e, desta forma, o débito cardíaco (DC. Este estudo tem como objetivo a avaliação da correlação entre o dióxido de carbono expirado (P ET CO2 e o débito cardíaco em pacientes submetidos à cirurgia cardíaca com circulação extracorpórea (CEC. MÉTODO: Foram estudados 25 pacientes submetidos à cirurgia de revascularização miocárdica com CEC. Após a intubação traqueal iniciou-se a monitorização da P ET CO2. A determinação do débito cardíaco (DC foi feita por método de termodiluição com o uso de cateter de Swan-Ganz e a PaCO2 foi avaliada através de gasometria arterial. Os parâmetros do estudo foram avaliados em quatro momentos: logo após a indução da anestesia geral; antes da circulação extracorpórea, ao término da circulação extracorpórea e ao final da cirurgia. RESULTADOS: O teste estatístico não demonstrou uma correlação entre o CO2 expirado e o DC, assim como o gradiente de dióxido de carbono arterial e expirado (Ga-eCO2 e o DC. Foi encontrada correlação entre a variação dos valores da P ET CO2, Ga-eCO2 e DC em relação ao basal antes da CEC com perda da correlação após a CEC até o final da cirurgia. CONCLUSÕES: Neste estudo, onde se avaliam pacientes submetidos à cirurgia cardíaca com CEC, as alterações de relação ventilação/perfusão ocorridas ao longo do procedimento são, provavelmente, os fatores determinantes da diminuição da correlação entre o débito cardíaco e o valor de dióxido de carbono expirado.JUSTIFICATIVA Y OBJETIVOS: El CO2 expirado (P ET CO2 refleja, además de la ventilación pulmonar (eliminación, la producción de dióxido de carbono (metabolismo y el

  17. ANÁLISIS DE LA CALIDAD DEL REGISTRO DE PARO CARDÍACO EN CASOS DE RESPONSABILIDAD MÉDICO LEGAL EN MÉDICOS GENERALES, 1999-2007 Quality of cardiac arrest records in cases of medical responsibility, 1999-2007

    Gabriel Barragán

    2009-01-01

    Full Text Available Antecedentes. El registro del paro cardíaco es una actividad que se debe acompañar en la reanimación cerebro cardio pulmonar. En Colombia no existe un formato de registro oficial de paro cardiorrespiratorio, lo que dificulta la investigación en reanimación y la conducción de los procesos de responsabilidad médica que se deriven de esta atención. Objetivo. Analizar la calidad del registro de paro cardíaco en casos de responsabilidad médico legal iniciada a médicos generales que tuvieron asesoría científica del Fondo para Auxilio de Demandas de la Sociedad Colombiana de Anestesiología y Reanimación (SCARE-FEPASDE, 1999-2007. Material y métodos. Se realizó una investigación tipo serie de casos, en donde se incluyeron los casos de paro cardiorrespiratorio que tuvieron demanda médico legal y que fueron atendidos por médicos generales, entre 1999 y 2007, y que requirieron asesoría jurídica por SCAREFEPASDE. La información se registró en tablas de Excel®, según las recomendaciones Utstein. La calificación de calidad se hizo por tres médicos expertos en responsabilidad médica de manera independiente. Se utilizó un formato de calificación sobre la proporción de registros realizados sobre 25 ítem posibles. La calidad se consideró alta (mayor de 95% ítem, media (70-94% ítem y baja (menor de 70%. En los casos de desacuerdo se realizó consenso. Resultados. Se incluyeron en total 83 casos. La calidad del registro del paro fue media en 49 casos (59%, baja en 32 casos (39% y alta en dos casos. Conclusión. El registro de paro cardiorrespiratorio en casos de responsabilidad médica es de mediana calidad, por lo que no se alcanza a cumplir con los estándares internacionales y las guías al estilo Utstein.Background. Cardiac arrest must be recorded when occurring during cardiopulmonary resuscitation. There is no official registration form for cardiac arrest in Colombia, thereby hampering research in resuscitation and managing

  18. Diagnósticos de Enfermagem em pacientes pós-cateterismo cardíaco: contribuição de Orem Diagnósticos de Enfermería en pacientes post-cateterismo cardiaco: contribuición de Orem Nursing Diagnoses in patients after heart catheterization: contribution of Orem

    Luciano Ramos de Lima

    2006-06-01

    Full Text Available Estudo de múltiplos casos, transversal, envolvendo 30 clientes, no período pós-cateterismo cardíaco. Objetivou estabelecer Diagnósticos de Enfermagem da North American Nursing Diagnosis Association (NANDA. O método de coleta de dados foi o Processo de Enfermagem fundamentado na Teoria Déficit do Autocuidado. Foram estabelecidos 25 diferentes Diagnósticos de Enfermagem. Todos os pacientes apresentaram Integridade tissular prejudicada; Risco para infecção; Dor aguda (região inguinal; Mobilidade física prejudicada, Déficit do autocuidado para higiene íntima e Risco para lesão orgânica renal. Conclui-se que a Teoria do Déficit de autocuidado facilitou a classificação de Diagnósticos de Enfermagem da NANDA, contribuindo para individualização, humanização e qualificação da assistência de enfermagem, além de promover o auto-conhecimento, auto-controle e a participação dos clientes no próprio cuidado.Estudio transversal de múltiplos casos, incluyendo 30 pacientes, en período post-cateterismo cardíaco. Con el objectivo de establecer Diagnósticos de Enfermería de North American Nursing Diagnosis Association (NANDA-Asociación Norteamericana de Diagnósticos de Enfermería.El método de recolecta de datos fue el Proceso de Enfermería, fundamentado en la Teoría de Déficit del Autocuidado de Dorothea Orem. Fueron establecidos 25 diferentes Diagnósticos de Enfermería. Todos los pacientes presentaron perfusión tisular perjudicada; Riesgo para infección; Dolor aguda em la región ingle, Movilidad física prejudicada. Déficit de autocuidado para higiene íntima y riesgo para lesión orgánica renal fue identificado en 100% de los pacientes. Se concluye que, la Teoría de Déficit de Autocuidado de Dorothea Orem, facilitó la clasificación de Diagnósticos de Enfermería de NANDA. Contribuyó para individualización, humanización y calificación de la asistencia de enfermería, incentivando la participación del

  19. Perspectivas da evolução clínica de pacientes com cardiomiopatia chagásica listados em prioridade para o transplante cardíaco Clinical perspectives of patients with Chagas cardiomyopathy listed as high priority for heart transplantation

    Luiz Felipe P. Moreira

    2005-09-01

    Full Text Available INTRODUÇÃO: O choque cardiogênico é responsável por elevados índices de mortalidade na fila de espera para o transplante cardíaco. Na cardiomiopatia chagásica, a alta incidência de disfunção biventricular pode contribuir com a gravidade desta complicação. MÉTODO: Foram estudados 141 pacientes indicados em caráter de prioridade para o transplante. Destes pacientes, 46 eram portadores de cardiomiopatia chagásica e 95 de outras cardiomiopatias. O choque cardiogênico foi tratado farmacologicamente e com o implante ocasional do balão intra-aórtico. Em cinco pacientes chagásicos, foi realizado o implante de dispositivo paracorpóreo de assistência ventricular esquerda. RESULTADOS: Num período médio de 2,8 meses, 58 (41,1% dos 141 pacientes foram transplantados, 73 (51,7% faleceram e 10 foram retirados da fila. A mortalidade entre os pacientes chagásicos e não chagásicos foi de 45,6% e 54,7%, respectivamente. No entanto, a expectativa média de vida, sem a realização do transplante cardíaco, dos pacientes chagásicos foi de apenas 1,5 meses, sendo observado risco relativo de mortalidade de 1,6 para estes pacientes em relação aos não chagásicos (pINTRODUCTION: Heart failure is responsible for high mortality rates of patients on heart transplantation waiting lists. In Chagas cardiomyopathy, the presence of biventricular dysfunction increases the severity of this situation. METHOD: One hundred and forty-one patients suffering from cardiogenic shock, listed as high priority for heart transplantation, were studied. Forty-six patients presented with Chagas cardiomyopathy and 95 with other cardiomyopathies. Heart failure was treated using intravenous inotropic drugs and intra-aortic balloon pump implantation. Five patients with Chagas disease underwent paracorporeal left ventricular assist device implantation. RESULTS: During a mean follow-up of 2.8 months, 58 (41.1% of the 141 patients were transplanted, while 73 (53.7% died

  20. Dimensão fractal na quantificação do grau de rejeição celular miocárdica pós-transplante cardíaco Fractal dimension in quantifying the degree of myocardial cellular rejection after cardiac transplantation

    Roberto Douglas Moreira

    2011-06-01

    Full Text Available INTRODUÇÃO: O termo "fractal" é derivado do latim fractus, que significa "irregular" ou "quebrado", considerando a estrutura observada como tendo uma dimensão não-inteira. Há muitos estudos que empregaram a Dimensão Fractal (DF como uma ferramenta de diagnóstico. Um dos métodos mais comuns para o seu estudo é a "Box-plot counting" (Método de contagem de caixas. OBJETIVO: O objetivo do estudo foi tentar estabelecer a contribuição da DF na quantificação da rejeição celular miocárdica após o transplante cardíaco. MÉTODOS: Imagens microscópicas digitalizadas foram capturadas na resolução 800x600 (aumento de 100x. A DF foi calculada com auxílio do "software ImageJ", com adaptações. A classificação dos graus de rejeição foi de acordo com a "Sociedade Internacional de Transplante Cardíaco e Pulmonar" (ISHLT 2004. O relatório final do grau de rejeição foi confirmado e redefinido após exaustiva revisão das lâminas por um patologista experiente externo. No total, 658 lâminas foram avaliadas, com a seguinte distribuição entre os graus de rejeição (R: 335 (0R, 214 (1R, 70 (2R, 39 (3R. Os dados foram analisados estatisticamente com os testes Kruskal-Wallis e curvas ROC sendo considerados significantes valores de P INTRODUCTION: The term "Fractal" is derived from the Latin fractus meaning "irregular" or "broken" considering the observed structure with a non-integer dimension. There are many studies which employed the Fractal Dimension (FD as a diagnostic tool. One of the most common methods for its study is the "Box Counting Method". OBJECTIVE: The aim of the present study was to try to establish the contribution of FD in the quantification of myocardial cellular rejection after cardiac transplantation. METHODS: Microscopic digital images were captured at 800x600 resolution (magnification 100x. FD was calculated with the aid of "ImageJ software" with adaptations. The classification of the degrees of rejection was in

  1. LUCHA TEMPERANTE Y ‘AMOR LIBRE’. ENTRE LO PROMETEICO Y LO DIONISÍACO: EL DISCURSO MORAL DE LOS ANARQUISTAS CHILENOS AL DESPUNTAR EL SIGLO XX THE STRUGGLE FOR TEMPERANCE AND ‘FREE LOVE’. BETWEEN THE PROMETHEAN AND THE DIONYSIAN: THE MORAL DISCOURSE OF THE CHILEAN ANARCHIST AT THE BEGINNING OF THE TWENTIETH CENTURY

    Eduardo A Godoy Sepúlveda

    2011-06-01

    Full Text Available En el siguiente artículo se aborda el discurso moral de los anarquistas chilenos de comienzos del siglo XX en torno al consumo de alcohol y las prácticas amorosas, a partir de las categorías analíticas del sociólogo francés Michael Maffesoli. Se postula que el discurso anarquista transitó indistintamente entre lo "prometeico" y lo "dionisíaco", ya que mientras, por una parte, la prensa ácrata repudió acérrimamente el consumo de alcohol, en tanto permitía la reproducción de la dominación política (y la subyugación económica de las clases dominantes, por otra, pregonó fórmulas amatorias antagónicas a las tradicionales, el "amor libre", sin ataduras jurídicas, ni religiosas.In the following article there is approached the moral speech of the Chilean anarchists of beginning of the 20th century concerning the consumption of alcohol and the loving practices from the analytical categories of the French sociologist Michael Maffesoli. It is postulated that the anarchistic speech passed indistinctly among the "promethean theory" and the "Dionysian thing", since that on one hand, the nonconformist press repudiated the consumption of alcohol, while, it was allowing the reproduction of the political domination and economic subjugation, on the other hand, it bet for antagonistic formulae of love on the traditional ones, the "free love ", without juridical ties, not religious.

  2. Um modelo experimental de ablação do Sistema Nervoso Intrínseco Cardíaco reduz a contratilidade do coração de ratos A new experimental model of chemical ablation of the Intrinsic Cardiac Nervous System reduces heart contractility and causes a type of dilated cardiopathy in rats

    Adilson Scorzoni Filho

    2004-09-01

    Full Text Available OBJETIVO: A função do Sistema Nervoso Intrínseco Cardíaco e o seu papel na doença cardíaca permanecem pobremente compreendidos. Sabe-se que o cloreto de benzalcônio (CB induz a desnervação intrínseca do tubo digestivo. O objetivo deste estudo foi tentar produzir um modelo experimental de desnervação intrínseca do coração utilizando o CB. MÉTODO: Trinta ratos Wistar foram submetidos à aplicação intrapericárdica de CB (0,3% e trinta animais controle receberam a solução salina. Após 15 dias, os animais foram divididos em três grupos, com 10 animais tratados e 10 controles em cada. Os animais do grupo I foram submetidos a estudo radiológico e histopatológico. A área cardíaca e o índice cardiotorácico (ICT foram medidos nas radiografias. Os animais do grupo II foram submetidos a estudo hemodinâmico com registro da pressão arterial, freqüência cardíaca e débito cardíaco. No grupo III, a integridade da inervação parassimpática extrínseca do coração foi avaliada por estimulação vagal direita. O sistema de condução foi avaliado pelo ECG basal. RESULTADOS: A aplicação de CB acarretou aumento do ICT, da área cardíaca, pressão arterial e débito cardíaco, bem como do peso ponderal e do fígado. Nestes animais, a análise histopatológica mostrou redução do número de neurônios atriais e congestão passiva crônica do fígado. A estimulação vagal não mostrou diferenças entre os grupos experimentais. CONCLUSÃO: A ablação do sistema nervoso intrínseco propiciou o aparecimento de cardiopatia dilatada com insuficiência cardíaca direita e esquerda. Esse modelo experimental inédito deverá nortear futuros estudos na tentativa da elucidação da relação entre lesão neuronal e miocardiopatia.OBJECTIVE: The function of Intrinsic Cardiac Nervous System is largely unknown, as is its role in heart disease. In the digestive system, a topic aplication of Benzalkonium chloride (BC leads to intrinsic

  3. Baixas doses de óxido nítrico na seleção dos pacientes candidatos a transplante cardíaco com hipertensão pulmonar Low doses of nitric oxide in the selection of candidates to heart transplantation with pulmonary hypertension

    Juan Alberto Cosquillo MEJIA

    2001-03-01

    Full Text Available A disfunção do ventrículo direito no pós-operatório do transplante cardíaco é uma complicação freqüente com morbimortalidade elevada. A avaliação hemodinâmica pulmonar dos candidatos precisa, às vezes, do emprego de prova farmacológica com o uso de drogas endovenosas vasodilatadoras tipo nitroprussiato de sódio (NTPNa, visando reduzir os níveis de pressão e resistência vascular pulmonar (RVP elevados a níveis compatíveis com os protocolos de inclusão dos Programas de Transplante Cardíaco. Valores de RVP acima de 6 unidades Wood sem droga vasodilatadora, ou acima de 2,5 com a utilização destas, excluem os pacientes do Programa. Entre janeiro de 1997 e janeiro de 2000 foram submetidos a cateterismo direito, 40 pacientes candidatos a transplante. A maioria homens, com idade mé (±12 anos. As etiologias mais encontradas foram miocardiopatia dilatada idiopática (59% e miocardiopatia isquêmica (25%. Todos em CF IV da NYHA, com fração de ejeção média do ventrículo esquerdo de 0,21 (± 0,03. A monitorização do débito cardíaco (DC, pressão da artéria pulmonar (PAP e RVP foi feita pelo método contínuo, utilizando para isto cateter de artéria pulmonar especial. Em 5 pacientes a prova farmacológica foi interrompida devido aos efeitos sistêmicos do NTPNa com queda da PAM, RVP e DC. Todos foram submetidos a inalação de óxido nítrico (NO por máscara, a uma dose de 20 ppm durante 10 minutos. Em 3, a RVP reduziu de 7,8 (±0,88 para 2,4 (±0,36 unidades Wood, e eles foram incluídos no Programa de Transplante. Nos outros 2, apesar de doses de NO de 20,30 e 40 ppm, a redução foi de 8,4 (±2,12 para 4,9 (±0,42 unidades Wood, ou seja, insuficiente para serem incluídos nos Programas de Transplante. Não tivemos óbitos, nem complicações durante os procedimentos. O NO inalatório na avaliação hemodinâmica dos candidatos a TC -- pelo seu efeito vasodilatador seletivo -- permite identificar aqueles com hiper

  4. Cardiopatia chagásica crônica causando insuficiência cardíaca congestiva na infância: estudo clínico e histopatológico de um caso, com ênfase para as lesões dos sistemas excito-condutor e nervoso autônomo intracardíaco

    Ademir Rocha

    1993-12-01

    Full Text Available Descreve-se caso de cardiopatia chagásica em menino de nove anos, natural e procedente do sulde Goiás, que desenvolveu insuficiência cardíaca congestiva quatro meses antes do óbito. As reações sorológicaspara doença de Chagas eram reagentes, epositivo o xenodiagnóstico. Os eletrocardiogramas mostraram taquicardia sinusal, extra-sístoles ventriculares e supraventriculares, hemibloqueio anterior esquerdo, bloqueio completo do ramo direito e sinais de sobrecarga de câmaras. O exame ecocardiográfico evidenciou dilatação de câmaras com hipocontratilidade difusa. O quadro se agravou progressivamente, complicando-se por vários episódios pneumônicos, o último dos quais provocou o óbito. A necrópsia, verificou-se, no coração, inflama ção crônica dos três folhetos, com miocardite crônica fibrosante predominando no septo interventricular e no ventrículo esquerdo. As estruturas componentes do sistema excito-condutor mostraram processoflogístico crônico, essencialmente exsudativo, ora discreto, ora moderado. No sistema nervoso autônomo intracardíaco constataram-se focos esparsos de discreta periganglionite crônica, e raros fenômenos degenerativos dos neurônios sem despopulação neuronal.A case of decompensated chagasic cardiopathy in a nine-year-old boy from the south of the State of Goiás, is described. He developed congestive heart failure four months before death. The sorological reaction for Chagas ' disease and the xenodiagnosis were positive. Electrocardiograms showed sinusal tachycardia, ventricular and supraventricular extrasystoles, left anterior hemiblock, complete right bundle branch block and signs of chambers overload. The echocardiogram demonstraded chamber dilatation with diffuse hypocontractility. He presented a downhill course complicated with several pneumonic episodes, the last one just before death. At necropsy, the heart, exhibited a chronicpancarditis with fibrosing chronic myocarditis involving

  5. Respostas cardiorrespiratórias durante exercício em portadores de transplante cardíaco. Análise ergoespirométrica comparativa com indivíduos normais Cardiorespiratory response during exercise in heart transplant recipients comparated to normal healthy subjects

    Ana Fátima Salles

    1998-01-01

    Full Text Available OBJETIVO: Avaliar as respostas cardiorrespiratórias dos portadores de transplante cardíaco (TxC. MÉTODOS: Submeteram-se a testes ergoespirométricos 9 portadores de TxC (GI, pareados por sexo, idade, peso e altura, com 9 indivíduos sedentários, aparentemente sadios (GII. Os pacientes eram do sexo masculino, com idade de 48±12 anos, com TFI (NYHA após 23±21 meses TxC. Faziam uso regular de ciclosporina, azatioprina, prednisona, dipiridamol e anti-hipertensivos. Os testes foram limitados por sintomas e interrompidos por exaustão. RESULTADOS: No pico do exercício, o GI apresentou desempenho significativamente inferior ao GII quanto ao VO2, VE, VEO2, FC, tempo de endurance e potência. No limiar anaeróbio, o GI apresentou VO2, tempo de endurance e potência significativamente inferior a do GII. Na potência de 40W o desempenho dos dois grupos foi similar. CONCLUSÃO: O GI apresentou desempenho cardiorrespiratório significativamente inferior no pico do exercício e similar na potência de 40W em relação ao GII, evidenciando os benefícios do TxC para cardiopatas em atividades habituaisPURPOSE: To evaluate the cardiorespiratory response of heart transplant (HT recipients. METHODS: Nine HT recipients (GI underwent ergospirometric tests and were compared to 9 apparently healthy, sedentary subjects with similar sex, age, weight and height (GII. All were male patients aging 48±12 years, in functional class I (NYHA an average of 23±21 months after HT. They were receiving cyclosporin, azathioprine, prednisone, dipyridamole and antihypertensive drugs. The tests were symptom-limited and they were interrupted due to exhaustion. RESULTS: During peak exercise, GI had a significantly lower physical performance related to lower VO2, VE, VEO2, HR, endurance time and work load. At the anaerobic threshold, VO2, endurance time and work load levels were also significantly lower in GI. The physical performance was similar between the groups in the 40W

  6. Avaliação e seguimento em médio prazo em candidatos a transplante cardíaco submetidos a exercício de baixa intensidade Assessment and medium-term follow up of heart transplant candidates undergoing low-intensity exercise

    Darlene Yuri Yoshimori

    2010-09-01

    Full Text Available OBJETIVOS: Estudar o comportamento cardiovascular e segurança frente a protocolo de exercícios de baixa intensidade em pacientes com insuficiência cardíaca (IC grave, candidatos a transplante cardíaco. MÉTODOS: Foram estudados 21 pacientes com IC grave, inscritos na lista de transplante cardíaco do Hospital Universitário da UNIFESP. Após avaliação, os pacientes foram monitorados durante a realização de protocolo de exercício com seis fases progressivas (1º membros superiores, 2º membros inferiores, 3º caminhada 35 m, 4º ½ lance de escada, 5º caminhada de 200 m e 6º 1 lance de escada, com intensidade estimada em 2 a 6 equivalentes metabólicos (1 MET = 3,5 ml de O2/kg/min.. Os pacientes foram acompanhados prospectivamente por aproximadamente 17 meses quanto à ocorrência de complicações clínicas e óbito. RESULTADOS: Dentre os pacientes estudados, três não foram capazes de realizar o protocolo completo, sendo as variáveis índice de massa corporal (IMC, pressão respiratória máxima (Pimáx e Pemáx, cmH2O e número de internações prévias, consideradas preditivas neste subgrupo. Frente ao protocolo de exercício, a frequência cardíaca (FC, bpm, duplo produto (DP, bpm x mmHg e escala de percepção de esforço (EP, Borg apresentaram maior oscilação, principalmente durante a fase 5 (H"5 METS, sendo considerados os melhores marcadores relativos ao esforço. A pressão arterial (PA, mmHg apresentou pouca oscilação. Não houve aumento da incidência de arritmias (Kappa=0,552 frente ao esforço. Observamos correlação positiva moderada entre a EP apenas na fase 6 (caminhada de 200m, com PA (r=0,4; P=0,02. Nos pacientes com desfecho óbito, foram observados valores reduzidos de PiMax na avaliação prévia. Durante o protocolo, redução da resposta de PA e maior elevação da resposta de FC. CONCLUSÃO: O comportamento cardiovascular frente ao protocolo de exercícios foi bem tolerado e seguro, mas reforça a

  7. Efficient Spatial Data mining using Integrated Genetic Algorithm and ACO

    K Sankar

    2011-05-01

    Full Text Available Spatial data plays a key role in numerous applications such as network traffic, distributed security applications such as banking, retailing, etc., The spatial data is essential mine, useful for decision making and the knowledge discovery of interesting facts from large amounts of data. Many private institutions, organizations collect the number of congestion on the network while packets of data are sent, the flow of data and the mobility of the same. In addition other databases provide the additional information about the client who has sent the data, the server who has to receive the data, total number of clients on the network, etc. These data contain a mine of useful information for the network traffic risk analysis. Initially study was conducted to identify and predict the number of nodes in the system; the nodes can either be a client or a server. It used a decision tree that studies from the traffic risk in a network. However, this method is only based on tabular data and does not exploit geo routing location. Using the data, combined to trend data relating to the network, the traffic flow, demand, load, etc., this work aims at deducing relevant risk models to help in network traffic safety task. The existing work provided a pragmatic approach to multi-layer geo-data mining. The process behind was to prepare input data by joining each layer table using a given spatial criterion, then applying a standard method to build a decision tree. The existing work did not consider multi-relational data mining domain. The quality of a decision tree depends, on the quality of the initial data which are incomplete, incorrect or non relevant data inevitably leads to erroneous results. The proposed model develops an ant colony algorithm integrated with GA for the discovery of spatial trend patterns found in a network traffic risk analysis database. The proposed ant colony based spatial data mining algorithm applies the emergent intelligent behavior of ant colonies. The experimental results on a network traffic (trend layer spatial database show that our method has higher efficiency in performance of the discovery process compared to other existing approaches using non-intelligent decision tree heuristics.

  8. Shared Savings Program ACO Provider-level RIF

    U.S. Department of Health & Human Services — The Centers for Medicare (CM) has created a set of standard analytical files that contain Shared Savings Program Accountable Care Organizations. Provider-level RIF...

  9. Laser induced bunch lengthening on the ACO storage ring FEL

    Robinson, K. E.; Madey, J. M. J.; Deacon, D. A. G.; Velghe, M. F.

    1983-03-01

    The experimental procedures and data obtained during a study of the laser-induced change in the electron bunch length are reported for trials with a free-electron laser (FEL). Bunch lengthening is thought to play a critical role in the efficiency and power output of an FEL. The experimental apparatus consisted of an external laser, an undulator ring, and a nonisochronous storage ring. Synchrotron light in the storage ring was measured by a photodiode, and bunch length changes were monitored by tuning the receiver mode to a harmonic of the orbit frequency. A Gaussian electron pulse shape was assumed, together with a Gaussian envelope for the Fourier transform, which was proven in a previous experiment. The power spectra of the photodiode were modeled analytically. It was found that high current conditions alter the electron excitation and require further theoretical modeling.

  10. MGA trajectory planning with an ACO-inspired algorithm

    Ceriotti, Matteo

    2011-01-01

    Given a set of celestial bodies, the problem of finding an optimal sequence of swing-bys, deep space manoeuvres (DSM) and transfer arcs connecting the elements of the set is combinatorial in nature. The number of possible paths grows exponentially with the number of celestial bodies. Therefore, the design of an optimal multiple gravity assist (MGA) trajectory is a NP-hard mixed combinatorial-continuous problem. Its automated solution would greatly improve the design of future space missions, allowing the assessment of a large number of alternative mission options in a short time. This work proposes to formulate the complete automated design of a multiple gravity assist trajectory as an autonomous planning and scheduling problem. The resulting scheduled plan will provide the optimal planetary sequence and a good estimation of the set of associated optimal trajectories. The trajectory model consists of a sequence of celestial bodies connected by twodimensional transfer arcs containing one DSM. For each transfer...

  11. Shared Savings Program ACO Beneficiary-level RIF

    U.S. Department of Health & Human Services — The Centers for Medicare (CM) has created a set of standard analytical files that contain Shared Savings Program Accountable Care Organizations. Beneficiary-level...

  12. Optimization of Association Rule Mining Apriori Algorithm Using ACO

    Badri Patel; Vijay K Chaudhari; Rajneesh K Karan; YK Rana

    2011-01-01

    Association rule mining is an important topic in data mining field. In a given large database of customer transactions. Each transaction consists of items purchased by a customer in a visit. Apriori algorithm that generates all significant association rules between items in the database. On the basis of the association rule mining and Apriori algorithm, this paper proposes an improved algorithm based on the Ant Colony Optimization algorithm. We can optimize the result generated by Apriori al...

  13. An ACO Algorithm for Effective Cluster Head Selection

    Sampath, Amritha; Thampi, Sabu M; 10.4304/jait.2.1.50-56

    2011-01-01

    This paper presents an effective algorithm for selecting cluster heads in mobile ad hoc networks using ant colony optimization. A cluster in an ad hoc network consists of a cluster head and cluster members which are at one hop away from the cluster head. The cluster head allocates the resources to its cluster members. Clustering in MANET is done to reduce the communication overhead and thereby increase the network performance. A MANET can have many clusters in it. This paper presents an algorithm which is a combination of the four main clustering schemes- the ID based clustering, connectivity based, probability based and the weighted approach. An Ant colony optimization based approach is used to minimize the number of clusters in MANET. This can also be considered as a minimum dominating set problem in graph theory. The algorithm considers various parameters like the number of nodes, the transmission range etc. Experimental results show that the proposed algorithm is an effective methodology for finding out t...

  14. Orchestrating ACO success: how top performers achieve shared savings.

    Harris, John M; Elizondo, Idette; Brown, Amanda M

    2016-03-01

    Leaders of the top-performing accountable care organizations in the Medicare Shared Savings Program attribute the success of their organizations in large part to seven strategies: Seek action-oriented leadership. Transform primary care physician practices. Keep patients out of the emergency department. Ensure all transitions are smooth. Make effective use of available data. Share information on physician performance. Keep patients engaged. PMID:27183758

  15. Ação do soro de cabra anti-soro de coelho imunizado ou não com células linfóides do doador sobre o alotransplante cardíaco em ratos: immunosupression of goat antiserum against rabbit serum immunized or not with donor lymphoid cells Cardiac allograft in rats

    Haylton Jorge Suaid

    2002-01-01

    Full Text Available INTRODUÇÃO: A rejeição imunológica é uma das principais causas da perda de órgãos transplantados. A tentativa do controle da reação imunológica é clinicamente feita através da imunossupressão inespecífica e experimentalmente também por bloqueio específico. O alotransplante cardíaco em ratos pela técnica de ONO,K é um bom método para avaliação clínica da rejeição e de estudos voltados para o controle da rejeição. Objetivo : estudar o efeito de um anti-antisoro linfocitário, anti-linfócitos do doador sobre a rejeição do alotransplante cardíaco de ratos Wistar para ratos Holtzman. MÉTODOS: o soro anti-linfocitário (SAL foi obtido através da imunização de coelhos com linfócitos obtidos de gânglios linfáticos da cadeia mesentérica de ratos Wistar, em solução de Tyrode, contendo 3x10(9 células/ ml. A inoculação de 3 coelhos foi feita com 1 ml da suspensão celular e 1 ml de adjuvante completo de Freund. Duas semanas após a primeira inoculação fez-se 4 doses semanais de reforço. Os coelhos foram sangrados na 5ª semana, quando então foram separados os soros. A titulação dos soros foi realizada pelo teste de citotoxicidade, sendo verificado que ambos apresentaram título de 1:1024. A dosagem de proteínas mostrou albumina com 3,1 e 2,7 g% e globulinas com 3,5 e 2,9 g%, sendo o normal 3,7 e 2,2 g% respectivamente. Os dois SAL foram misturados. Duas cabras foram inoculados, com 3 ml da mistura desses SAL, associados a 2 ml de adjuvante de Freund. As doses de reforço com 5 ml do SAL foram iniciadas 2 semanas após. A cabra A recebeu 8 doses (1,4 g de globulinas. A cabra B recebeu 4 doses de reforço (0,7 g de globulinas. Uma semana após a última inoculação retirou-se 125 ml de sangue de cada cabra, fazendo a separação dos anti-soro anti-SAL (ASAL. Uma terceira cabra C foi imunizada com soro normal de coelho. A determinação de precipitinas foi feita pelo método de OUCHTERLONY. O ASAL A teve t

  16. Evaluation of the mitochondrial respiration of cardiac myocytes in rats submitted to mechanical bile duct obstruction Avaliação da respiração mitocondrial de miócitos cardíacos em ratos ictéricos sumetidos à obstrução do ducto biliar

    Rafael Kemp

    2008-01-01

    Full Text Available PURPOSE: The objective of the present study was to evaluate the capacity of the myocardium for energy production by the analysis of mitochondrial respiration in rats with jaundice submitted to bile duct ligature. METHODS: Sixteen male Wistar rats were divided into 2 Groups: Group SO submitted to nontherapeutic laparotomy (sham operation and Group IC (icteric group submitted to bile duct ligature. After 7 days, laparotomy was again performed in all animals for cardiac muscle extraction and analysis. Mitochondrial oxygen consumption was determined by stage 3 velocity and stage 4 velocity. The respiratory control ratio (RCR was obtained by the ratio of stage 3 to stage 4 velocity. Statistical analysis was performed by the Mann-Whitney test, with the level of significance set at 5% (pOBJETIVO: A proposta deste trabalho é avaliar a capacidade de produção energética do miocárdio mediante análise da respiração mitocondrial em ratos ictéricos submetidos à ligadura do ducto biliar. MÉTODOS: Foram utilizados 16 ratos Wistar machos divididos em 2 Grupos: Grupo SO , os quais foram submetidos à Laparotomia branca e Grupo IC, os quais sofreram ligadura do ducto biliar para o desenvolvimento de icterícia obstrutiva. Todos os animais após 7 dias de cirurgia foram submetidos à nova laparotomia para extração e análise do músculo cardíaco. O consumo de oxigênio pelas mitocôndrias foi determinado pela velocidade do estado 3 e velocidade do estado 4. A razão do controle respiratório (RCR foi obtida pela relação entre as velocidades dos estados 3 e 4. A análise estatística foi feita pelo teste de Mann-Whitney com nível de significância de 5 % (p<0.05. RESULTADOS: Observou-se queda estatisticamente significante nos valores do consumo de oxigênio do estado 3 da respiração mitocondrial no grupo IC em relação ao SO, no entanto os valores para estado 4 permaneceram basicamente inalterados entre os grupos. Os valores de RCR entre os

  17. Guidelines for specialized nutritional and metabolic support in the critically-ill patient: Update. Consensus SEMICYUC-SENPE: Cardiac patient Recomendaciones para el soporte nutricional y metabólico especializado del paciente crítico: Actualización. Consenso SEMICYUC-SENPE: Paciente cardíaco

    F. J. Jiménez Jiménez

    2011-11-01

    a veces precisará suplementación con nutrición parenteral. La hiperglucemia aguda sostenida en las primeras 24 h en pacientes ingresados por síndrome coronario agudo, sean o no diabéticos, es un factor de mal pronóstico en términos de mortalidad a los 30 días. En el paciente crítico cardíaco con fallo hemodinámico en situación estable, un soporte nutricional de 20-25 kcal/kg/día es eficaz para mantener un estado nutricional adecuado. El aporte proteico debe ser de 1,2-1,5 g/kg/día. Se administrarán fórmulas poliméricas o hiperproteicas habituales, según la situación nutricional previa del paciente, con restricción de sodio y volumen según su situación clínica. La glutamina es la mayor fuente de energía para el miocito, vía conversión a glutamato, protegiendo además a la célula miocárdica de la isquemia en situaciones críticas. La administración de 1 g/día de ω-3 (EpA+DHA, en forma de aceite de pescado, puede prevenir la muerte súbita en el tratamiento del síndrome coronario agudo y también puede contribuir a una disminución de los ingresos hospitalarios, por eventos cardiovasculares, en la insuficiencia cardíaca crónica.

  18. Perfil sérico da molécula de adesão intercelular-1 no pós-operatório cardíaco de lactentes submetidos à circulação extracorpórea Intercellular adhesion molecule-1 serum profile in cardiac postoperative period of infants undergoing cardiopulmonary bypass

    Angela Hunsche

    2002-01-01

    Full Text Available Objetivos: mensurar os níveis séricos da molécula de adesão intercelular-1, solúvel em condições basais e após exposição ao circuito de circulação extracorpórea, em lactentes submetidos à cirurgia cardíaca para correção de defeitos cardíacos congênitos. Métodos: estudo de coorte contemporâneo envolvendo 21 lactentes submetidos à cirurgia cardíaca com uso de circulação extracorpórea. Foram medidos os níveis séricos da molécula de adesão intercelular-1, solúvel na indução anestésica, ao término e 8 e 26 horas após o término da circulação extracorpórea. As amostras foram dosadas através do método de ELISA. Resultados: as patologias cardíacas congênitas mais comuns foram defeito do septo atrioventricular e Tetralogia de Fallot. As médias de idade e de peso foram 6,6 meses e 5,8 quilos. As medianas dos tempos de circulação extracorpórea e de clampeamento da aorta foram, respectivamente, 87 e 53 minutos. Todos os lactentes utilizaram inotrópicos. As medianas dos tempos de intubação e de internação foram 72 horas e 21 dias. A taxa de mortalidade dos pacientes foi de 9,5%. Os níveis basais da molécula avaliada foram mais elevados do que aqueles considerados normais (pObjective: to measure the intercellular adhesion molecule-1 serum levels at baseline and after cardiopulmonary bypass exposure in infants undergoing surgery of congenital heart disease. Methods: contemporary cohort study, which consisted of 21 infants undergoing cardiac surgery with cardiopulmonary bypass. The intercellular adhesion molecule-1 serum levels were measured at induction of anesthesia, at the end of cardiopulmonary bypass, and 8 hours and 26 hours after cardiopulmonary bypass. The samples were measured using ELISA. Results: atrioventricular septal defects and tetralogy of Fallot were the most common congenital cardiac pathologies. The age and weight mean values were 6.6 months and 5.8 Kg. The median values of cardiopulmonary

  19. Pressão expiratória positiva na via aérea por máscara facial na hemodinâmica de pós-operatórios cardíacos Expiratory positive airway pressure in postoperative cardiac hemodynamics

    Ana Claudia Borges dos Santos Sena

    2010-10-01

    Full Text Available FUNDAMENTOS: A pressão expiratória positiva na via aérea por máscara facial (EPAP é utilizada no pós-operatório de cirurgias cardíacas, entretanto, seus efeitos hemodinâmicos não foram claramente estudados. OBJETIVO: Avaliar as alterações hemodinâmicas causadas pela EPAP em pacientes pós-cirurgia cardíaca monitorados por cateter de Swan-Ganz. MÉTODOS: Foram incluídos no estudo, pacientes no primeiro ou segundo pós-operatório de cirurgia cardíaca, estáveis hemodinamicamente e com cateter de Swan-Ganz. Eles foram avaliados em repouso e após o uso de 10 cmH2O de EPAP, de forma randomizada. As variáveis estudadas foram: saturação de oxigênio, frequências cardíaca e respiratória, pressões arteriais médias sistêmica e pulmonar (PAM e PAMP, pressões venosa central (PVC e de oclusão da atéria pulmonar (POAP, débito e índice cardíacos, e resistências vasculares sistêmica e pulmonar. Os pacientes foram divididos em subgrupos (com fração de ejeção 50% e os dados foram comparados por teste t e ANOVA. RESULTADOS: Vinte e oito pacientes foram estudados (22 homens, idade média 68 ± 11 anos. Comparando o período de repouso versus EPAP, as alterações observadas foram: POAP (11,9 ± 3,8 para 17,1 ± 4,9 mmHg, p BACKGROND: Expiratory positive airway pressure (EPAP is used in after cardiac surgeries. However, its hemodynamic effects have not been clearly studied. OBJECTIVE: To evaluate the hemodynamic changes caused by EPAP in patients after cardiac surgery monitored by Swan-Ganz. METHODS: Patients at the first or second cardiac surgery postoperative period hemodynamically stable with a Swan-Ganz catheter were included in the study. They were assessed at rest and after using 10 cmH2O EPAP at random. The variables studied were: oxygen saturation, heart rate and respiratory rate, mean artery pressures and pulmonary artery mean pressures (MAP and PAMP, central venous pressure (CVP and pulmonary capillary wedge pressure

  20. Débito cardíaco e fração de ejeção fetal por meio do spatio-temporal image correlation (STIC: comparação entre fetos masculinos e femininos Fetal cardiac output and ejection fraction by spatio-temporal image correlation (STIC: comparison between male and female fetuses

    Christiane Simioni

    2012-06-01

    Full Text Available OBJETIVO: Comparar do débito cardíaco (DC e a fração de ejeção (FE do coração de fetos masculinos e femininos obtidos por meio da ultrassonografia tridimensional, utilizando o spatio-temporal image correlation (STIC. MÉTODOS: Realizou-se um estudo de corte transversal com 216 fetos normais, entre 20 a 34 semanas de gestação, sendo 108 masculinos e 108 femininos. Os volumes ventriculares no final da sístole e diástole foram obtidos por meio do STIC, sendo as avaliações volumétricas realizadas pelo virtual organ computer-aided analysis (VOCAL com rotação de 30º. Para o cálculo do DC utilizou-se a fórmula: DC= volume sistólico/frequência cardíaca fetal, enquanto que para a FE utilizou-se a fórmula: FE= volume sistólico/volume diastólico final. O DC (combinado, feminino e masculino e a FE (masculina e feminina foram comparadas utilizando-se o teste t não pareado e ANCOVA. Foram criados gráficos de dispersão com os percentis 5, 50 e 95. RESULTADOS: A média do DC combinado, DC direito, DC esquerdo, FE direita e FE esquerda, para feminino e masculino, foram 240,07 mL/min; 122,67 mL/min; 123,40 mL/min; 72,84%; 67,22%; 270,56 mL/min; 139,22 mL/min; 131,34 mL/min; 70,73% e 64,76%, respectivamente; sem diferença estatística (P> 0,05. CONCLUSÕES: O DC e a FE fetal obtidos por meio da ultrassonografia tridimensional (STIC não apresentaram diferença significativa em relação ao gênero.OBJECTIVE: To compare the cardiac output (CO and ejection fraction (EF of the heart of male and female fetuses obtained by 3D-ultrasonography using spatio-temporal image correlation (STIC. METHODS: We conducted a cross-sectional study with 216 normal fetuses, between 20 and 34 weeks of gestation, 108 male and 108 female. Ventricular volumes at the end of systole and diastole were obtained by STIC, and the volumetric assessments performed by the virtual organ computer-aided analysis (VOCAL rotated 30º. To calculate the DC used the formula

  1. Associação independente do tabagismo aos eventos cardíacos pós-operatórios e à mortalidade em 30 dias Asociación independiente del tabaquismo a los eventos cardiacos postoperatorios y a la mortalidad a 30 días Independent association of smoking with postoperative cardiac events and thirty-day mortality

    Luciane Midory Sakuma

    2010-05-01

    Full Text Available FUNDAMENTO: Há poucos estudos que demonstrem a associação do tabagismo, como fator de risco independente, aos eventos cardíacos pós-operatórios. OBJETIVO: Avaliar a associação do tabagismo, como variável independente, às complicações cardiovasculares pós-operatórias e à mortalidade em 30 dias em operações não cardíacas. MÉTODOS: Utilizou-se coorte retrospectiva de um hospital geral, na qual foram incluídos 1.072 pacientes estratificados em tabagistas atuais (n = 265, ex-tabagistas (n = 335 e não tabagistas (n = 472. Esses três grupos foram analisados para os desfechos cardiovasculares combinados no pós-operatório (infarto, edema pulmonar, arritmia com instabilidade hemodinâmica, angina instável e morte cardíaca e mortalidade em 30 dias. Utilizaram-se o teste qui-quadrado e a regressão logística, considerando p FUNDAMENTO: Existen pocos estudios que demuestren la asociación del tabaquismo, como factor de riesgo independiente, a los eventos cardiacos postoperatorios. OBJETIVO: Evaluar la asociación del tabaquismo, como variable independiente, a las complicaciones cardiovasculares postoperatorias y a la mortalidad a 30 días en operaciones no cardiacas. MÉTODOS: Se utilizó una cohorte retrospectiva de un hospital general, en la que fueron incluidos 1.072 pacientes estratificados en tabaquistas actuales (n = 265, ex-tabaquistas (n = 335 y no tabaquistas (n = 472. Se analizaron en estos tres grupos las complicaciones cardiovasculares combinadas en el postoperatorio (infarto, edema pulmonar, arritmia con inestabilidad hemodinámica, angina inestable y muerte cardiaca y la mortalidad a 30 días. Se utilizaron el test de chi-cuadrado y la regresión logística, considerando pBACKGROUND: Few studies have demonstrated the association of smoking, as an independent risk factor, with postoperative cardiac events. OBJECTIVE: To evaluate the association of smoking, as an independent variable, with postoperative cardiovascular

  2. Cytomegalovirus and other herpesviruses infections in heart and bone marrow transplant recipients Infecções causadas por citomegalovírus e outros vírus do grupo herpes em transplantados cardíacos e de medula óssea

    Adriana Weinberg

    1990-10-01

    Full Text Available From January 1988 to January 1989 all the heart transplant and bone marrow recipients at the Instituto do Coração of the Hospital das Clínicas of the University of São Paulo Medical School were studied for the incidence and morbidity associated with herpesviruses infections after transplantation. Five bone marrow and 5 heart transplant recipients were followed for a mean of 4.2 months post-transplantation. All the patients were seropositive for cytomegalovirus (CMV before admission and 80% experienced one or more recurrences during the observation period. Of the 12 episodes of CMV infection, that were identified in this study, 83% were accompanied by clinical or laboratory abnormalities. However, there was only one case of severe disease. The overall incidence of infection for herpes simplex (HSV was 50%. Although most of HSV reactivations were oral or genital, one case of HSV hepatitis occurred. One of the 6 episodes of HSV infections that were treated with acyclovir showed an unsatisfactory response and was successfully managed with ganciclovir. All the individuals had anti-varicella zoster virus antibodies, but none of them developed infection. The study emphasizes the importance of active diagnostic surveillance of herpesvirus infections in transplant patients. Both CMV and HSV reactivations showed high incidence and important morbidity and thus, deserve prophylactic therapy.De janeiro de 1988 a janeiro de 1989 todos os pacientes submetidos a transplante de coração ou de medula óssea no Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo foram estudados quanto à incidência e morbidade das infecções pós-transplante causadas por vírus do grupo herpes. Cinco recipientes de medula óssea e 5 transplantados cardíacos foram observados por um período médio de 4.2 meses após o transplante. Todos os pacientes tinham sorologia positiva para citomegalovírus (CMV antes do transplante

  3. Pneumonia por Influenza A(H1N1 em paciente imunossuprimido após transplante cardíaco Neumonía por Influenza A (H1N1 en paciente inmunosuprimido tras transplante cardiaco Influenza A (H1N1 pneumonia in an immunossupressed patient after heart transplantation

    Fernando Bacal

    2009-12-01

    Full Text Available O papel da resposta imunológica durante a infecção pelo vírus Influenza H1N1 não está totalmente estabelecido, mas acredita-se que atue de forma decisiva no agravamento do quadro e no aparecimento da síndrome de desconforto respiratório agudo. O papel de terapias imunomoduladoras no controle de infecções virais também não é consensual e faltam dados de literatura para se definir as indicações de seu uso. Neste relato de caso, apresentamos, segundo nosso conhecimento, pela primeira vez, o relato de um paciente transplantado cardíaco que apresentou infecção pelo vírus H1N1 e evoluiu de forma favorável, trazendo um questionamento sobre o real papel da terapia imunossupressora como fator de risco para a forma grave da doença.El rol de la respuesta inmunológica durante la infección por el virus Influenza H1N1 no está totalmente establecido, sino que se cree que él actúe de forma decisiva en el agravamiento del cuadro y en el surgimiento del síndrome de distrés respiratorio agudo. El papel de terapias inmunomoduladoras en el control de infecciones virales también no es consensual y nos faltan datos de la literatura para definirse las indicaciones de su utilización. En este caso clínico presentamos, según nuestro conocimiento, por primera vez, el relato de un paciente transplantado cardiaco que presentó infección por el virus H1N1 y evolucionó de forma favorable, y aprovechamos para poner en cuestión el real papel de la terapia inmunosupresora como factor de riesgo para la forma severa de la enfermedad.The role of the immune response during Influenza H1N1 virus infection is not yet fully established, but it is believed that it decisively participates in the severity of the disease as well as in the development of acute respiratory distress syndrome. The role of immunomodulating therapies in the control of viral infections is not a consensus either, and data from the literature defining the indications for their use

  4. Deleção 22q11.2 em pacientes com defeito cardíaco conotruncal e fenótipo da síndrome da deleção 22q11.2 Deleción 22q11.2 en pacientes con defecto cardiaco conotruncal y fenotipo del síndrome de la deleción 22q11.2 22q11.2 deletion in patients with conotruncal heart defect and del22q syndrome phenotype

    Sintia Iole Nogueira Belangero; Fernanda T.S. Bellucco; Leslie Domenici Kulikowski; Christofolini, Denise M; Mirlene C. S. P. Cernach; Maria Isabel Melaragno

    2009-01-01

    FUNDAMENTO: A síndrome da deleção 22q11.2 é a mais freqüente síndrome de microdeleção humana. O fenótipo é altamente variável e caracterizado por defeito cardíaco conotruncal, dismorfias faciais, insuficiência velofaríngea, dificuldade de aprendizagem e retardo mental. OBJETIVO: O objetivo deste trabalho foi investigar a freqüência da deleção 22q11.2 em uma amostra brasileira de indivíduos portadores de cardiopatia conontrucal isolada e do fenótipo da síndrome da deleção 22q11.2. MÉTODOS: Vin...

  5. Peso dos ventrículos cardíacos determinado em necropsia de indivíduos saudáveis mortos por causas externas Cardiac ventricular weights recorded at the autopsy of healthy subjects who died of external causes

    Sérgio Lamêgo Rodrigues

    2007-11-01

    Full Text Available OBJETIVO: Determinar o peso dos ventrículos cardíacos em necropsia de indivíduos sadios vítimas de morte acidental, visando determinar padrões de normalidade em nossa população. MÉTODOS: Foram examinados 94 corações no Instituto Médico Legal de Vitória. Após remoção do coração e ressecção dos átrios e gordura epicárdica, os ventrículos direito (VD e esquerdo (VE, incluindo o septo, foram separados e pesados e a massa indexada pela altura. O teste de Kolmogorov-Smirnov foi usado para testar normalidade da distribuição. Os dados são apresentados como média ± desvio padrão. RESULTADOS: Após 12 exclusões (doença cardiovascular possível detectada após a morte foram analisados 82 corações (52 homens e 30 mulheres, 16-68 anos, média 31±12 anos. O peso do VE foi de 181±25 g e 125±15 g, do VD foi de 54±7 g e 38±6 g e a massa de VE indexada pela altura foi de 105±14 g/m e 78±8 g/m para homens e mulheres, respectivamente. O P95 do peso do VE foi de 218 g e 128 g/m em homens e 148 g e 88 g/m em mulheres. Não detectamos correlação significante entre a massa ventricular e idade. CONCLUSÃO: O peso do ventrículo esquerdo do coração dos homens da nossa amostra foi superior aos relatados na literatura contemporânea. Nossos resultados sugerem que a presença de hipertrofia de VE pode ser inferida em presença de massa de VE superior a 218 g ou 128 g/m nos homens e 148 g ou 88 g/m nas mulheres.OBJECTIVE:To establish cardiac ventricular weights recorded during the autopsy of healthy individuals who died of external causes, aiming at determining normality patterns in our population. METHODS:A total of 94 hearts were evaluated at the Forensics Department of the city of Vitória, Espírito Santo. After the heart removal and resection of the atria and epicardial fat, the right ventricle (RV and the left ventricle (LV, including the septum, were separated and weighed and the mass was indexed by the height. The Kolmogorov

  6. Uso de endoprótesis en el tratamiento de lesiones no oclusivas del territorio iliaco Uso de endoprótese no tratamento de lesões não-oclusivas do território ilíaco

    Renato Mertens

    2006-06-01

    íacas. Entretanto, o uso desses procedimentos para tratar outros tipos de lesão ainda não foi bem estudado. Nosso objetivo é analisar indicações e resultados do uso de endoprótese em lesões ilíacas não-oclusivas. MATERIAL E MÉTODOS: Revisamos retrospectivamente os registros de 14 pacientes consecutivos, todos homens, com idade média de 61,6 anos (faixa: 25-80 anos, tratados por via endovascular entre 2001 e 2006 por lesões ilíacas não-oclusivas. O estudo pré e pós-operatório incluiu tomografia computadorizada. O procedimento foi realizado em bloco cirúrgico, utilizando um angiógrafo digital. Foi utilizado acesso femoral, com a inserção de endopróteses tubulares. RESULTADOS: Em 11 pacientes, houve embolização de artéria hipogástrica ipsilateral associada. As patologias tratadas foram: oito aneurismas ateroscleróticos, 3 dissecções, 2 lesões traumáticas e um pseudo-aneurisma anastomótico. A comorbidade mais freqüente foi hipertensão, em 43% dos casos. Não houve mortalidade operatória. Um paciente apresentou um pseudo-aneurisma femoral tratado com compressão. Um paciente tratado por fístula arteriovenosa traumática em nível ilíaco teve sua insuficiência cardíaca resolvida, com persistência assintomática de mínimo fluxo. A estada pós-operatória foi de 3 dias (média. Não se apresentaram outras endofugas inciais ou tardias. Durante um acompanhamento médio de 20,5 meses (faixa de 1 a 49 meses, um paciente morreu de câncer e nenhum requereu procedimentos complementares. CONCLUSÃO: O tratamento endovascular de lesões ilíacas através de endoprótese é seguro e permite um resultado durável no manejo de um amplo espectro de patologias.

  7. Comparação dos efeitos da dobutamina e da milrinona sobre a hemodinâmica e o transporte de oxigênio em pacientes submetidos à cirurgia cardíaca com baixo débito cardíaco após indução anestésica Comparación de los efectos de la dobutamina y de la milrinona sobre la hemodinámica y el transporte de oxígeno en pacientes sometidos a cirugía cardiaca con bajo débito cardiaco después de inducción anestésica Comparison of the effects of dobutamine and milrinone on hemodynamic parameters and oxygen supply in patients undergoing cardiac surgery with low cardiac output after anesthetic induction

    Maria José Carvalho Carmona

    2010-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Diversas classes de fármacos inotrópicos, com efeitos hemodinâmicos diferentes, são utilizadas no tratamento do baixo débito cardíaco em pacientes com disfunção sistólica submetidos a procedimento cirúrgico cardíaco. O objetivo deste estudo foi comparar o efeito da dobutamina e da milrinona sobre a hemodinâmica e o transporte de oxigênio nessa população de pacientes. MÉTODO: Após aprovação do Comitê de Ética institucional e obtenção do consentimento escrito pós-informado, 20 pacientes submetidos à cirurgia cardíaca e com índice cardíaco JUSTIFICATIVA Y OBJETIVOS: Diversas clases de fármacos inotrópicos con efectos hemodinámicos diferentes, se usan en el tratamiento del bajo débito cardíaco en pacientes con disfunción sistólica sometidos al procedimiento quirúrgico cardíaco. El objetivo de este estudio, fue comparar el efecto de la dobutamina y de la milrinona sobre la hemodinámica y el transporte de oxígeno en esa población de pacientes. MÉTODO: Después de la aprobación del Comité de Ética institucional y de la obtención del consentimiento informado, 20 pacientes sometidos a la cirugía cardíaca y con índice cardíaco BACKGROUND AND OBJECTIVES: Several classes of inotropic drugs with different hemodynamic effects are used in the treatment of low cardiac output in patients with diastolic dysfunction undergoing cardiac surgery. The objective of the present study was to compare the effects of dobutamine and milrinone on hemodynamic parameters and oxygen supply in this population of patients. METHODS: After approval by the Ethics Committee of the institution and signing of the informed consent, 20 patients undergoing cardiac surgery with cardiac index < 2 L.min-1.m2 after anesthetic induction and place ment of a pulmonary artery catheter were randomly divided to receive dobutamine 5 µg.kg-1. min-1 (n = 10, or milrinone 0.5 µg.kg-1.min-1 (n = 10. Hemodynamic parameters were

  8. Avaliação do peptídeo natriurético tipo B no diagnóstico de rejeição após transplante cardíaco pediátrico Evaluación del péptido natriurético tipo B en el diagnóstico de rechazo tras transplante cardiaco pediátrico B-type natriuretic peptide assessment in the diagnosis of rejection after pediatric heart transplant

    Cristina de Sylos

    2009-03-01

    Full Text Available FUNDAMENTO: A rejeição constitui-se em uma das principais causas de mortalidade após o transplante cardíaco pediátrico. O peptídeo natriurético tipo B (BNP tem sido estudado como método no diagnóstico de rejeição aguda, especialmente em pacientes adultos submetidos a transplante cardíaco. OBJETIVO:Correlacionar o nível sérico de BNP à rejeição aguda diagnosticada pela biópsia endomiocárdica em pacientes do grupo de transplante cardíaco pediátrico. MÉTODOS:Foram coletadas 50 amostras de BNP de 33 crianças em pós-operatório de transplante cardíaco e analisados dados de idade, sexo, cor, grupo sangüíneo, painel imunológico, tempo de evolução após o transplante, classe funcional, imunossupressão utilizada e número de rejeições. RESULTADOS:Foram 33 crianças com idade mediana de 10,13 anos, predomínio do sexo feminino (54% e da cor branca (78%. No momento da dosagem de BNP o tempo médio de transplante foi 4,25 anos. A biópsia endomiocárdica diagnosticou nove rejeições em oito pacientes (27%, sendo três com grau 3 A, cinco com grau 2 e um com rejeição humoral. No momento da biópsia, a maioria dos pacientes encontrava-se assintomática. O nível sérico de BNP foi em média 77,18 pg/ml, sendo 144,22 pg/ml no grupo com rejeição e 62,46 pg/ml no grupo sem rejeição, com p = 0,02. CONCLUSÃO: Crianças assintomáticas podem apresentar rejeição aguda no pós-operatório de transplante cardíaco. O nível sérico de BNP apresentou diferença estatisticamente significante no grupo com rejeição, podendo ser método adicional no diagnóstico de rejeição cardíaca.FUNDAMENTO: El rechazo constituye una de las principales causas de mortalidad tras el transplante cardiaco pediátrico. El péptido natriurético tipo B (BNP ha sido estudiado como método en el diagnóstico de rechazo agudo, sobre todo en pacientes adultos sometidos a transplante cardiaco. OBJETIVO:Correlacionar el nivel sérico de BNP al rechazo

  9. Tratamento da luxação paralítica do quadril na paralisia cerebral tetraparética espástica com osteotomia do fêmur e do ilíaco sem abertura da cápsula articular (capsuloplastia Hip dislocation treatment in cerebral palsy patients with spastic quadriplegia with femoral and pelvic osteotomies, without opening of the joint capsule (capsuloplasty

    Fernando Farcetta Junior

    2010-01-01

    Full Text Available OBJETIVO: Mostrar o planejamento pré-operatório, e os resultados do tratamento cirúrgico da luxação paralítica do quadril em pacientes com paralisia cerebral. A técnica utilizada foi a osteotomia derrotatória e varizante do fêmur proximal, associada à osteotomia do ilíaco tipo Dega, sem abertura da cápsula articular. MÉTODOS: Realizamos um estudo retrospectivo de 10 quadris em oito pacientes com paralisia cerebral tipo tetraparesia espástico, submetidos a tratamento cirúrgico entre 2003 e 2005 com a mesma técnica cirúrgica. Foram avaliados parâmetros clínicos e radiográficos pré e pós-operatórios, bem como o planejamento pré-operatório com uso do intensificador de imagem. Os parâmetros clínicos analisados foram: dor, dificuldade de higiene e dificuldade de posicionamento. Os parâmetros radiológicos foram os índices de Reimers, índice acetabular e ângulo cervicodiafisário. Estes resultados foram submetidos a análise estatística. RESULTADOS: Obtivemos bons resultados com esta técnica. Com um seguimento médio de três anos, todos os quadris estavam reduzidos na última consulta, com alto grau de satisfação dos familiares, em relação ao tratamento. Além disso, mostramos que o planejamento pré-operatório com uso do intensificador de imagem nos permite a redução e estabilização desses quadris sem a necessidade de capsuloplastia. CONCLUSÃO: Os autores concluíram que no tratamento da luxação do quadril dos pacientes com paralisia cerebral tetraparéticos espásticos com o planejamento pré-operatório, não é necessária a capsuloplastia para estabilização da articulação coxofemoral.OBJECTIVES: To show the preoperative planning and the results of surgical treatment for paralytic hip dislocation in children with cerebral palsy. The techniques used were proximal femoral varus derotation osteotomy and Dega osteotomy without opening of the joint capsule. METHODS: We performed a retrospective review of

  10. Doença celíaca: avaliação da obediência à dieta isenta de glúten e do conhecimento da doença pelos pacientes cadastrados na Associação dos Celíacos do Brasil (ACELBRA Celiac disease: evaluation of compliance to a gluten-free diet and knowledge of the disease in celiac patients registered at the Brazilian Celiac Association (BCA

    Vera Lucia SDEPANIAN

    2001-10-01

    Full Text Available Racional — A obediência à dieta isenta de glúten previne a ocorrência de complicações malignas e não-malignas. Objetivo - Avaliar a obediência à dieta isenta de glúten e o conhecimento teórico acerca da doença celíaca e seu tratamento pelos pacientes cadastrados na Associação dos Celíacos do Brasil (ACELBRA. Métodos - Foi enviado por correio um questionário a respeito da obediência à dieta isenta de glúten e do conhecimento teórico da doença celíaca e seu tratamento a 584 membros cadastrados na ACELBRA. Resultados - Dos 534 (91,4% questionários recebidos, foram analisados 529 (90,6%. Quanto à obediência à dieta, 69,4% dos pacientes responderam que nunca ingerem glúten e 29,5% que não obedecem à dieta. A proporção de pacientes que ingerem glúten freqüentemente ou sem restrição alguma é maior entre aqueles com idade igual ou maior a 21 anos (17,7% do que os com idade menor (9,9%. A freqüência de obediência à dieta foi maior quando o intervalo de tempo em que foi estabelecido o diagnóstico da doença foi inferior a 5 anos. O intestino delgado foi assinalado como o principal órgão afetado na doença celíaca por 82% dos pacientes. Os principais sintomas assinalados foram diarréia (96,6%, emagrecimento (93,4%, barriga inchada (90,4%, anemia (68,1% e vômitos (59,6%. Apenas 59,0% concordaram com a existência de predisposição genética. Segundo 90,4% das respostas, a doença é permanente e 96,2% assinalaram que a dieta deve ser totalmente isenta de glúten; 67,1% responderam que o glúten é uma proteína que está presente, segundo 92,1% dos inquéritos, no trigo, centeio, cevada e aveia. Observou-se maior proporção de obediência à dieta quando há conhecimento da doença e dieta. A biopsia de intestino delgado foi considerada necessária por apenas 67,5% dos pacientes, observando-se maior freqüência de obediência à dieta nos pacientes que realizaram pelo menos uma biopsia de intestino delgado

  11. An Optimized Feature Selection for Image Classification Based on SVM-ACO

    Priyanka Dhasal; Shiv Shakti Shrivastava; Hitesh Gupta; Parmalik Kumar

    2012-01-01

    Multi- class classification plays an import role in image classification. Multi-class classification used different classifier for the classification of data, such as binary classifier and support vector machine. In this dissertation we proposed a feature sampling technique of image classification. Our sampling technique optimized the feature selection process and reduced the unclassified region in multi-class classification. For the process of optimization we used ant colony optimization alg...

  12. Routing in Wireless Sensor Networks Using an Ant Colony Optimization (ACO) Router Chip.

    Okdem, Selcuk; Karaboga, Dervis

    2009-01-01

    Wireless Sensor Networks consisting of nodes with limited power are deployed to gather useful information from the field. In WSNs it is critical to collect the information in an energy efficient manner. Ant Colony Optimization, a swarm intelligence based optimization technique, is widely used in network routing. A novel routing approach using an Ant Colony Optimization algorithm is proposed for Wireless Sensor Networks consisting of stable nodes. Illustrative examples, detailed descriptions and comparative performance test results of the proposed approach are included. The approach is also implemented to a small sized hardware component as a router chip. Simulation results show that proposed algorithm provides promising solutions allowing node designers to efficiently operate routing tasks. PMID:22399947

  13. Dependência tabágica, assertividade e alexitimia em doentes cardíacos

    Vânia Rocha

    2010-08-01

    Full Text Available O tabagismo é uma das principais causas evitáveis de morte, aumentando acentuadamente o risco de infarto do miocárdio. Este último está associado a certas variáveis psicossociais relacionadas com o tabagismo, nomeadamente a alexitimia e a falta de assertividade. O objetivo do presente artigo foi caracterizar os dois tipos de dependência tabágica (fisiológica e comportamental, a assertividade e a alexitimia, e avaliar a relação das variáveis entre si, em 30 doentes homens internados com infarto. Foram aplicados o Teste de Fagerström, o Questionário de Glover-Nilsson, a Escala de "Rathus" e a TAS-20. Os resultados indicam que a alexitimia encontra-se relacionada com a dependência comportamental e com a assertividade, sugerindo que os sujeitos menos assertivos e com dificuldade em gerir afetos negativos e situações de estresse, podem recorrer ao tabagismo como mecanismo de enfrentamento. Nas intervenções voltadas à interrupção do hábito de fumar em doentes infartados deve-se enfatizar as competências sociais e de regulação emocional.

  14. Lo demoníaco en "El concepto de la angustia"

    Negre Rigol, Monserrat

    1995-01-01

    La libertad es la posibilidad que hace a los individuos capaces de desarrollar un tipo de existencia que lleva consigo un gran desarrollo de su subjetividad. Esto requiere tomar conciencia de que Dios es el creador del hombre. Los individuos que desean ser absolutamente independientes, pueden rechazar esta condición, rebelándose contra Dios. Pero la consecuencia que se deriva de ello es la absoluta imposibilidad de comunicación, la soledad, el aburrimiento, y un constante rechazo de abrirse a...

  15. Asfixia perinatal e problemas cardíacos Perinatal asphyxia and heart problems

    Gesmar Volga H. Herdy

    1998-08-01

    Full Text Available OBJETIVO: Avaliar a gravidade das complicações cardíacas na asfixia neonatal, sua evolução e correlacioná-las com o grau e duração do processo hipóxico. MÉTODOS: Foram estudados 90 bebês nos últimos 7 anos com grau de Apgar PURPOSE: To evaluate the severity of cardiac complications of neonatal asphyxia in relation to the length and degree of hipoxia. METHODS: Ninety babies with an Apgar score <6 were examined in the intensive care unit at our institution during seven years. Arterial blood for measuring pH, glucose, LDH and MB fraction of CK, together with serial electrocardiogram (ECG, echocardiogram and chest X rays was obtained. The fatal cases were studied with macro and microscopic examination. RESULTS: From a total of 90 cases, 73 were premature: 30 (41% appropriate for gestation age (AGA and 43 (59% small for gestation age (SGA. Twenty one (23% cases had arterial pH <7.2. The most common clinical conditions were: pneumonia 28 (31%, anemia 24 (26% and jaundice 12 (13%. The main cardiological findings were: systolic murmur in 46 (50%, signs of heart hypertrophy in 18 (20% and heart failure in 8 (9%. On ECG the main findings were ST and T abnormalities. The echocardiogram showed a patent ductus arteriosus (PDA in 20 (22%, tricuspid regurgitation in 6 (7%, pulmonary hypertension in 6 (7%, dyskinesia and ventricular dilatation in 4 (5%. Necropsy was performed in 23 cases and macro and microscopy obtained in 14; the most frequent findings were: myocite necrosis in 8 (54%, congestion, vacuolization and loss of striae in 4 (29%. CONCLUSION: In the majority of cases, patients had a benign course, even those presenting with severe acidemia. Many abnormal EKGs and echocardiograms became normal after a few weeks. Among those who had a fatal outcome, the severity of histological lesions was observed in babies who had suffered asphyxia for more prolonged periods.

  16. Routing in Wireless Sensor Networks Using an Ant Colony Optimization (ACO Router Chip

    Dervis Karaboga

    2009-02-01

    Full Text Available Wireless Sensor Networks consisting of nodes with limited power are deployed to gather useful information from the field. In WSNs it is critical to collect the information in an energy efficient manner. Ant Colony Optimization, a swarm intelligence based optimization technique, is widely used in network routing. A novel routing approach using an Ant Colony Optimization algorithm is proposed for Wireless Sensor Networks consisting of stable nodes. Illustrative examples, detailed descriptions and comparative performance test results of the proposed approach are included. The approach is also implemented to a small sized hardware component as a router chip. Simulation results show that proposed algorithm provides promising solutions allowing node designers to efficiently operate routing tasks.

  17. Corpo estranho intracardíaco: complicação da ventriculoauriculostomia

    Gilberto Machado de Almeida

    1965-09-01

    Full Text Available A ventriculoauriculostomia, apesar das complicações que pode determinar, continua a ser a técnica cirúrgica mais freqüentemente usada para o tratamento da hidrocefalia. Na literatura, existe referência a apenas três casos em que a extremidade inferior do sistema de derivação deslocou-se para o ventrículo direito. Nestes doentes o corpo estranho foi retirado ci-rùrgicamente. Apresentamos um caso operado segundo a técnica de Spitz-Holter, com embolização cardíaca pelo cateter jugular. O doente permanece há 22 meses com o corpo estranho no coração direito, porque a família não permitiu que fôsse realizada a cardiotomia.

  18. Routing in Wireless Sensor Networks Using an Ant Colony Optimization (ACO) Router Chip

    Dervis Karaboga; Selcuk Okdem

    2009-01-01

    Wireless Sensor Networks consisting of nodes with limited power are deployed to gather useful information from the field. In WSNs it is critical to collect the information in an energy efficient manner. Ant Colony Optimization, a swarm intelligence based optimization technique, is widely used in network routing. A novel routing approach using an Ant Colony Optimization algorithm is proposed for Wireless Sensor Networks consisting of stable nodes. Illustrative examples, detailed descriptions a...

  19. AN ADAPTIVE ACO-DRIVEN SCHEME FOR LEARNING AIM ORIENTED PERSONALIZED E-LEARNING

    Sushma Hans

    2014-10-01

    Full Text Available The e-learning paradigm is now a well-established vehicle of modern education. It caters to a wide spectrum of students with diverse backgrounds who enroll with their own learning aims. A core challenge under this scenario is to generate personalized learning paths so that each student can achieve her learning aim most effectively. Prior works used static attributes such as prior knowledge level, learning ability, browsing preferences, learning style etc. to generate personalized learning paths. In this paper, we take an entirely new route by taking into account the continuous improvement of a learner in the light of her own learning aim, to redefine her learning path at each level of the course. We introduce the concept of personalized examination system that systematically evaluates the dynamic learning ability of every student according to her pre-set goals. The proposed intelligent e-learning system uses Ant Colony Optimization to iteratively optimize the forward learning paths. Experimental results reveal that the system is able to tap a student’s improved learning ability to choose more difficult paths that contribute highly towards her own aims. We demonstrate that the overall learning success of weaker students doubles as compared to statically generated paths while there is considerable improvement of 50% in the learning success for average students as well. This clearly indicates that our approach gives realistic benefits to initially weak students who gradually evolve as the course progresses.

  20. ACO Algorithm Applied to Multi-Objectives Optimization of Capacity Expansion in Next Generation Wireless Network

    Dac-Nhuong Le

    2013-09-01

    Full Text Available The optimal capacity expansion of base station subsystems in Next Generation Wireless Network (NGWN problem with respect to multi-demand type and system capacity constraints is known to be NP-complete. In this paper, we propose a novel ant colony optimization algorithm to solve a network topology has two levels in which mobile users are sources and both base stations and base station controllers are concentrators. There are two important aspects of upgrading to NGWN. The first importance of backward compatibility with pre-existing networks, and the second is the cost and operational benefit of gradually enhancing networks, by replacing, upgrading and installing new wireless network infrastructure elements that can accommodate both voice and data demand. Our objective function is the sources to concentrators connectivity costas well as the cost of the installation, connection, replacement, and capacity upgrade of infrastructure equipment. We evaluate the performance of our algorithm with a set of real world and data randomly generated. Numerical results show that our algorithms is a promising approach to solve this problem.

  1. Fibroma cardíaco mimetizando cardiomiopatia hipertrófica Cardiac fibroma mimicking hypertrophic cardiomyopathy

    Luís Alberto Dallan

    1989-12-01

    Full Text Available É relatado o caso de paciente com queixa de dor precordial, dispnéia e arritmia desde a adolescência, tratada clinicamente por mais de 10 anos. Nesse período, foi submetida a inúmeros exames ângio e ecocardiográficos, com suspeita inicial de endomiocardiofibrose e, posteriormente, de cardiomiopatia hipertrófica de ventrículo esquerdo. Como houve piora progressiva da sintomatologia e ausência de resposta à medicação, foi encaminhada ao nosso Serviço, onde se diagnosticou fibroma de ventrículo esquerdo. Foi submetida, com sucesso, à ressecção cirúrgica do tumor, sendo realizada reconstrução geométrica do ventrículo esquerdo. Apresenta boa evolução, decorridos dois anos, com remissão completa dos sintomas. Destacamos a dificuldade no diagnóstico diferencial desses tumores benignos e de crescimento lento, com as cardiomiopatias hipertróficas do ventrículo esquerdo.A 33 year-old woman was seen, for the first time, ten years ago, for evaluation of a recurrent chest pain, dyspnea and arrhythmia. She was submitted to echocardiographic studies and a cardiac catheterization. The diagnoses was endomyocardial fibrosis at first, and hypertrophic cardiomyopathy after. Despite treatment with propranolol and quinidine, the episodes of dyspnea and tachyarrhythmias became more frequent and severe, and the patient was guided to our Service. Cardiac re-catheterization, echocardiographic and computed tomography studies identified in traumural cardiac fibroma and the patient was referred for surgical treatment. The cardiac fibroma was successfully resected on extracorporeal bypass and with cardioplegic arrest of the heart. Repair of the heart was accomplished with a patch placed to close the left ventricular cavity. The postoperative course was uncomplicated, and she remains assymptomatic two years later. We have emphazied tha this tumor often produces clinically obscure disease, simulating particularly the left ventricle hypertrophic cardiomiopathy.

  2. Caracterización molecular de la microbiota de individuos celíacos

    SÁNCHEZ SÁNCHEZ, ESTER

    2013-01-01

    La enfermedad celíaca (EC) es una enteropatía de carácter autoinmune en la que intervienen factores genéticos y ambientales. Es la enfermedad crónica intestinal más frecuente, y aunque puede presentarse a cualquier edad y con una gran variedad de síntomas, los casos típicos suelen manifestarse durante la infancia y cursar con síntomas gastrointestinales. En individuos genéticamente susceptibles a desarrollar la enfermedad la ingesta del gluten de la dieta causa una inflamación crónica en el i...

  3. Observation of the substructure in the electron bunch on the ACO storage ring

    In the future, one interesting point of the SRFEL at Orsay will be the microtemporal analysis of the laser beam correlated with that of the electron bunch. In a first time, we have only analysed the temporal structure of the electron bunch with an Electrophotonic streak camera. The first results seem to indicate that the bunch is not an homogeneous bunch but presents a substructure. We discuss with details this data

  4. AN ADAPTIVE ACO-DRIVEN SCHEME FOR LEARNING AIM ORIENTED PERSONALIZED E-LEARNING

    Sushma Hans; Chakraverty, S.; Aditya Bindal

    2014-01-01

    The e-learning paradigm is now a well-established vehicle of modern education. It caters to a wide spectrum of students with diverse backgrounds who enroll with their own learning aims. A core challenge under this scenario is to generate personalized learning paths so that each student can achieve her learning aim most effectively. Prior works used static attributes such as prior knowledge level, learning ability, browsing preferences, learning style etc. to generate personalized learning pat...

  5. A Model for Creative Products to Forecast and It’s Production Plan Solved by ACO

    Deyan Zeng; Tinggui Chen

    2013-01-01

    Creative product is special product, which has characteristics like short product life cycle, big market risk and so on. The market is changed very soon, and the needs of customers are changed quickly, too. In order to increase the profit and decrease the cost, it is necessary to forecast the demand and make production plan. The product plan is developed according to the quantity of demand, but creative product has no historical sell data to base on, what’s more, the demand is unknowabl...

  6. Multi-objective integrated process planning and scheduling : a hybrid MAS/ACO approach

    Zhang, Sicheng.; 张思成

    2015-01-01

    Process planning and scheduling are two important manufacturing planning functions which are traditionally performed separately and sequentially. Usually, the process plan has to be prepared first before scheduling can be performed. However, due to the complexity of manufacturing systems and the uncertainties encountered in practical production, the sequentially prepared process plans and schedules may sometimes become inefficient or even infeasible. Integrated process planning and scheduling...

  7. A Novel Framework for Medical Web Information Foraging Using Hybrid ACO and Tabu Search.

    Drias, Yassine; Kechid, Samir; Pasi, Gabriella

    2016-01-01

    We present in this paper a novel approach based on multi-agent technology for Web information foraging. We proposed for this purpose an architecture in which we distinguish two important phases. The first one is a learning process for localizing the most relevant pages that might interest the user. This is performed on a fixed instance of the Web. The second takes into account the openness and dynamicity of the Web. It consists on an incremental learning starting from the result of the first phase and reshaping the outcomes taking into account the changes that undergoes the Web. The system was implemented using a colony of artificial ants hybridized with tabu search in order to achieve more effectiveness and efficiency. To validate our proposal, experiments were conducted on MedlinePlus, a real website dedicated for research in the domain of Health in contrast to other previous works where experiments were performed on web logs datasets. The main results are promising either for those related to strong Web regularities and for the response time, which is very short and hence complies the real time constraint. PMID:26573642

  8. Contribución al estudio de los micropotenciales cardíacos

    Vargas Drechsler, Manuel

    1996-01-01

    El objetivo principal de la tesis es el análisis y la reducción del ruido en la electrocardiografía de alta resolución con el propósito de mejorar la detección de los potenciales ventriculares tardíos. La hipótesis es que un cuidadoso análisis del ruido y de las técnicas empleadas actualmente para su reducción permitirá proponer mejoras a dichas técnicas. En otra tesis (Fernández, 1996) se estudian diversos métodos de reducción de ruido en el momento de realizar la adquisición, tales como el ...

  9. Deleção 22q11.2 em pacientes com defeito cardíaco conotruncal e fenótipo da síndrome da deleção 22q11.2 Deleción 22q11.2 en pacientes con defecto cardiaco conotruncal y fenotipo del síndrome de la deleción 22q11.2 22q11.2 deletion in patients with conotruncal heart defect and del22q syndrome phenotype

    Sintia Iole Nogueira Belangero

    2009-04-01

    Full Text Available FUNDAMENTO: A síndrome da deleção 22q11.2 é a mais freqüente síndrome de microdeleção humana. O fenótipo é altamente variável e caracterizado por defeito cardíaco conotruncal, dismorfias faciais, insuficiência velofaríngea, dificuldade de aprendizagem e retardo mental. OBJETIVO: O objetivo deste trabalho foi investigar a freqüência da deleção 22q11.2 em uma amostra brasileira de indivíduos portadores de cardiopatia conontrucal isolada e do fenótipo da síndrome da deleção 22q11.2. MÉTODOS: Vinte e nove pacientes foram estudados por meio de citogenética clássica, por hibridação in situ fluorescente (FISH e por técnicas moleculares. RESULTADOS: A análise citogenética por meio de bandamento G revelou cariótipo normal em todos os pacientes, com exceção de um que apresentou cariótipo 47,XX,+idic(22(q11.2. Com o uso de técnicas moleculares, a deleção foi observada em 25% dos pacientes, todos portadores do fenótipo da síndrome da deleção 22q11.2. Em nenhum dos casos, a deleção foi herdada dos pais. A freqüência da deleção 22q11.2 foi maior no grupo de pacientes portadores do espectro clínico da síndrome da deleção 22q11.2 do que no grupo de pacientes com cardiopatia conotruncal isolada. CONCLUSÃO: A investigação da presença da deleção e sua correlação com os dados clínicos dos pacientes podem auxiliar os pacientes e suas famílias a terem um melhor aconselhamento genético e um seguimento clínico mais adequado.FUNDAMENTO: El síndrome de la deleción 22q11.2 es el más frecuente síndrome de microdeleción humana. El fenotipo, altamente variable, se caracteriza por defecto cardiaco conotruncal, dismorfias faciales, insuficiencia velofaríngea, dificultad de aprendizaje y retardo mental. OBJETIVO: El objetivo de este trabajo fue investigar la frecuencia tanto de la deleción 22q11.2 en una muestra brasileña de individuos portadores de cardiopatía conotrucal aislada, como del fenotipo del s

  10. O exercício físico atenua o déficit autonômico cardíaco induzido pelo bloqueio da síntese do óxido nítrico El ejercicio físico atenúa el déficit autonómico cardiaco inducido por el bloqueo de la síntesis de óxido nítrico Physical exercise attenuates the cardiac autonomic deficit induced by nitric oxide synthesis blockade

    Bruno Rafael Orsini Rossi

    2009-01-01

    Full Text Available FUNDAMENTO: O bloqueio da síntese do óxido nítrico (NO é caracterizado pelo aumento da atividade simpática cardíaca, e o treinamento físico promove a redução da atividade simpática. OBJETIVO: Investigamos o efeito do bloqueio da síntese do NO sobre o controle autonômico cardiovascular em ratos submetidos ao exercício aeróbio durante dez semanas. MÉTODOS: Ratos wistar foram divididos em quatro grupos: controle tratados com ração e água ad libitum durante dez semanas (RC; controle tratados com N G-nitro-L-arginine methyl ester (L-NAME na última semana (RCL; treinados durante dez semanas em esteira motorizada (RT; treinados por dez semanas e tratados com L-NAME na última semana (RTL. O controle autonômico cardiovascular foi investigado em todos os grupos com a utilização de duplo bloqueio com metilatropina e propranolol, e análise da variabilidade. RESULTADOS: Os grupos RCL e RTL apresentaram hipertensão. O grupo RCL apresentou taquicardia e predomínio do tônus simpático na determinação da FC após o bloqueio autonômico farmacológico. O grupo RT apresentou bradicardia e menor freqüência cardíaca (FC intrínseca em relação aos demais. A avaliação da variabilidade da FC mostrou menores valores absolutos e normalizados na banda de baixa freqüência (BF no grupo RCL. Por sua vez, o grupo RTL apresentou elevação na banda de BF em valores absolutos. A análise da variabilidade da PAS mostrou que os grupos RCL e RTL apresentaram maiores valores na banda de BF. CONCLUSÃO: O exercício físico prévio impediu o déficit no controle autonômico cardíaco induzido pelo tratamento com L-NAME, no entanto não impediu o aumento na variabilidade da PAS.FUNDAMENTO: El bloqueo de la síntesis de óxido nítrico (NO se caracteriza por el incremento de la actividad simpática cardiaca, y el entrenamiento físico promueve la reducción de la actividad simpática. OBJETIVO: Investigamos el efecto del bloqueo de la s

  11. Equipment stainless steel entire versus steels bimetallics clad or overlay; Utilizacao de equipamentos de processo construidos em aco inoxidavel integral versus acos bimetalicos cladeado ou 'overlay'

    Batista, Itamar da Silva; Lima, Jadival Carneiro de; Leal, Murilo Fonseca; Cardoso, Amauri dos Santos; Jorjan, Roberto [PETROBRAS S.A., Sao Francisco do Conde, BA (Brazil). Refinaria Landulfo Alves Mataripen (RLAM)

    2008-07-01

    This study does not recommend the use of a pressure vessel made of integral stainless steel, due to the failure mechanisms under stress corrosion assisted by chlorides or polythionic acid. Are presented case studies of literature and analysis of reports of proceedings of RLAM reactors, showing that the materials produced by bimetallic clad overlay or are more appropriate, in terms of integrity, for use in equipment that the internal environment requires austenitic stainless steel specification.

  12. Vale do Aco pipeline: pipeline natural gas implementation in ArcelorMittal Monlevade steel work; Gasoduto Vale do Aco: implantacao do gas natural via gasoduto na ArcelorMittal Monlevade

    Goncalves, Eduardo Sergio da Silva; Arantes, Luiz Flavio Mourao; Ribeiro, Vicente Aleixo Pinheiro [ArcelorMittal Monlevade, Joao Monlevade, MG (Brazil)

    2011-12-21

    Since September 2010, ArcelorMittal Monlevade has gained flexibility and an important opportunity to reduce the cost of its energy mix due to the arrival of the Natural Gas (NG) via Steel Valley Pipeline. The proposal of the project included the substitution of the Liquefied Petroleum Gas (LPG), Fuel Oil and Compressed Natural Gas for natural gas via pipeline. To support the investment decision, in addition to domestic economic and technical aspects, the macro economic environment concerning the NG was also taken into account. This paper shows the analysis for adjustment of internal equipment, the structure of the contract, the conceptual project of the gas distribution built inside the main events, the gains achieved, the alternatives for the acquisition of NG and operational flexibility of ArcelorMittal Monlevade in case of interruption of supply of natural gas. (author)

  13. Mechanical And Microstructural Evaluation Of A Wear Resistant Steel; Avaliacao mecanica e microestrutural de um aco resistente ao desgaste

    Santos, F.L.F. dos; Vieira, A.G.; Correa, E.C.S.; Pinheiro, I.P., E-mail: falletti@hotmail.co [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET/MG), Belo Horizonte, MG (Brazil). Dept. de Engenharia de Materiais

    2010-07-01

    In the present work, the analysis of the mechanical properties and the microstructural features of a high strength low alloy steel, containing chromium, molybdenum and boron, subjected to different heat treatments, was conducted. After austenitizing at 910 deg C for 10 minutes, three operations were carried out: oil quenching, oil quenching followed by tempering at 200 deg C for 120 minutes and austempering at 400 deg C for 5 minutes followed by water cooling. The analysis was performed through tensile and hardness tests, optical microscopy and X-ray diffraction. The bainitic structure led to high strength and toughness, both essential mechanical properties for wear resistant steels. The occurrence of allotriomorphic ferrite and retained austenite in the samples also increased the wear resistance. This phenomenon is related to the fact that both structures are able to be deformed and, in the case of the retained austenite, the transformation induced plasticity TRIP effect may take place as the material is used. (author)

  14. Regulación fisiológica del cotransportador sodio/bicarbonato cardíaco

    Orlowski, Alejandro

    2014-01-01

    El objetivo del presente trabajo de tesis doctoral es estudiar y caracterizar la formación de un complejo físico-funcional entre el cotransporte sodio/bicarbonato electrogénico Na+/HCO3- (NBCe1) y la AC IX.

  15. Del conocimiento y enseñanza de los indios, según José de Aco

    Alejandro SANVISENS MARFULL

    2011-07-01

    Full Text Available RESUMEN: Tenemos algún conocimiento del sistema de crianza que algunos pueblos indios americanos tenían y transmitían de generación en generación. Según esto, los modos de enseñanza de los indios americanos, especialmente por lo que se refiere a la juventud, se ponen de manifiesto, si no en toda su extensión, por lo menos en grado suficiente para que podamos pensar y hablar de una pedagogía subyacente en ciertos pueblos de la América precolombina. El jesuita José de Acosta (1539-16001, que vivió en Centroamérica y en América del Sur y conoció directamente los usos y costumbres de los indios americanos, en su valiosa Historia natural y moral de las Indias

  16. Vers une coordination d'équipes de secours lors de situations de crise : un algorithme ACO prometteur

    Jason Mahdjoub; Francis Rousseaux

    2014-01-01

    Résumé. La gestion de crise pose plusieurs défis aux concepteurs de systèmes d'aide à la décision. Nous proposons dans cet article de traiter la question de la conception de systèmes aptes à orienter intelligemment la coordination des équipes de secours. Un des défis est de permettre au système de fonctionner avec des moyens de communication dégradés. Nous avons développé un modèle d'optimisation par colonies de fourmis, capable de gérer la complexité inhérente dans le déploiement des ressour...

  17. Hydroxyapatite coating on stainless steel by biomimetic method; Recobrimento de hidroxiapatita em acos inoxidaveis austeniticos pelo metodo biomimetico

    Dias, V.M.; Maia Filho, A.L.M.; Silva, G.; Sousa, E. de; Cardoso, K.R., E-mail: katiarc@univap.b [Universidade do Vale do Paraiba (IPD/UNIVAP), Sao Jose dos Campos, SP (Brazil). Inst. de Pesquisa e Desenvolvimento

    2010-07-01

    Austenitic stainless steels are widely used in implants due to their high mechanical strength and corrosion, however, are not able to connect to bone tissue and were classified as bioinert. The calcium phosphate ceramics such as hydroxyapatite (HA) are bioactive materials and create strong chemical bonds with bone tissue, but its brittleness and low fracture toughness render its use in conditions of high mechanical stress. The coating of steel with the bioactive ceramics such as HA, combines the properties of interest of both materials, accelerating bone formation around the implant. In this study, austenitic stainless steel samples were coated with apatite using the biomimetic method. The effect of three different surface conditions of steel and the immersion time in the SBF solution on the coating was evaluated. The samples were characterized by SEM, EDS and X-ray diffraction. (author)

  18. Swarm Intelligence Based Ant Colony Optimization (ACO) Approach for Maximizing the Lifetime of Heterogeneous Wireless Sensor Networks

    LingaRaj.K

    2013-01-01

    This paper attempts to undertake the study of maximizing the lifetime of Heterogeneous wireless sensor networks (WSNs). In wireless sensor networks, sensor nodes are typically power-constrained with limited lifetime, and thus it is necessary to know how long the network sustains its networking operations. Heterogeneous WSNs consists of different sensor devices with different capabilities. We can enhance the quality of monitoring in wireless sensor networks by increasing the coverage area....

  19. Characterization of alonized steel used in the oil industry; Caracterizacao de acos alonizados utilizados na industria do petroleo

    Cortes Paredes, Ramon; D' Oliveira, Ana Sofia C.M.; Capra, Andre [Parana Univ., Curitiba, PR (Brazil). Dept. de Engenharia Mecanica]. E-mails: ramon@demec.ufpr.br; sofmat@demec.ufpr.br; capra@demec.ufpr.br

    2001-07-01

    The problems and the damages caused by the corrosion in the production and refining of the oil are enormous. In the process of refining it is present among other substances, naphtenic gas where the character of the corrosive attack is significantly aggressive. The deterioration provoked by hydrogen is the most harmful deterioration in an oil refinery. There are several publications that certify eht excellent protection conferred to the steel in industrial atmosphere given by aluminum coating. This covering represents a pure ideal compromise between the passive protection and the active protection. Moreover, the presence of a metal to metal layer (Fe/Al) in the zone between aluminum and steel, obtained by additional thermal heat treatment, represents an additional protective barrier, in particular against the diffusion of hydrogen in the steel in environments that contains naphtenic gas ou sulfide acid. In industrial scale, tubes are manufactured through the process of alonizing and it is already used in the Presidente Getulio Vargas Refinery - REPAR, PR, Brazil. The process require a heat treatment to allow the diffusion of aluminum in the tube in order to form the Fe/Al intermetallic, which presents recognized resistance to the sulfurous corrosive environment in the oil refining. This was the motivation for the characterization of these alonized steel in order to determine what types of intermetallic are formed. Test samples have been prepared and optic and electronic microscopy examinations was varied out. The studied alonized surface showed enhanced hardness and additionally, it was observed that the aluminum diffusion permits the formation of a different types of Fe/Al. It was also found the presence of aluminum without the formation of intermetallic. (author)

  20. Natural gas use in treatment of steel surfaces; Utilizacao de gas natural em tratamento de superficies de aco

    Ferraz, Andre Dias; Machado, Antonio Rogerio; Rocha, Ivan; Azevedo, Jorge; Oshiro, Hugo K.; Konishi, Ricardo; Lehmkuhl, Willian [Companhia de Gas de Santa Catarina (SCGAS), Florianopolis, SC (Brazil); Piazza, Walter [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2011-12-21

    The surface treatments of metals, such as carburizing, rely on processing under high temperature in carbon rich atmospheres. The atmosphere is industrially generated using the partial oxidation of a carbon rich fuel, such as propane, butane or methanol. This article reports a study of the production of a carburizing atmosphere for surface treatment of steel from the partial oxidation of natural gas in a catalytic reactor. The reactor studied was a production size reactor with 300 mm of diameter and 1500 mm of length, packed with alumina supported nickel catalyst. The quality of the carburizing gas was evaluated from its carbon potential of the carburizing gas that was calculated from the concentrations of carbon monoxide (CO), carbon dioxide (CO{sub 2}), oxygen (O{sub 2}) and methane (CH{sub 4}) measured at the reactor's exit. The results indicate that CO concentration is very close to equilibrium, while CO{sub 2} is higher and CH{sub 4} is lower. Examining the reactor, the conclusion was that there was an axial temperature gradient, resulting in lower residence time under the required processing temperature. This resulted in smaller decomposition of CH{sub 4} and smaller production of CO{sub 2}. An equilibrium calculation of carbon potential, expressed as weight percent of carbon in iron, was developed to predict the possible optimizations of mixture composition and reactor temperature for a given required carbon potential. Conclusion: it is possible to generate a carburizing atmosphere under well controlled and repeatable conditions for the carbon potentials required for surface carburizing of steels in industrial processing using natural gas and air mixtures. (author)

  1. Evaluation of welding by MIG in martensitic stainless steel; Avaliacao da soldagem pelo processo MIG em aco inoxidavel martensitico

    Fernandes, M.A. [Universidade Estadual de Campinas (UNICAMP), SP (Brazil); Mariano, N.A.; Marinho, D.H.C. Marinho, E-mail: neideaparecidamariano@gmail.co [Universidade Federal de Alfenas (UNIFAL), Pocos de Caldas, MG (Brazil)

    2010-07-01

    This work evaluated structure's characterization and mechanical properties after the welding process of the stainless steel CA6NM. The employed welding process was the metal active gas with tubular wire. The control of the thermal cycle in the welding process has fundamental importance regarding the properties of the welded joint, particularly in the thermally affected zone. The mechanical properties were appraised through impact resistance tests and the hardness and microstructure through metallographic characterization and Ray-X diffraction. The parameters and the process of welding used promoted the hardness and toughness appropriate to the applications of the steel. Welding energy's control becomes an essential factor that can affect the temperature of carbide precipitation and the nucleation of the retained austenite in the in the region of the in the thermally affected zone. (author)

  2. Hydrogen embrittlement of super austenitic stainless steel welded joints; Fragilizacao por hidrogenio em juntas soldadas de acos inoxidaveis superausteniticos

    Paredes, Ramon S. Cortes [Parana Univ., Curitiba, PR (Brazil). Centro Politecnico. Inst. de Tecnologia para o Desenvolvimento (LACTEC); Berthier, Thiana; Kuromoto, Neide K. [Parana Univ., Curitiba, PR (Brazil). Lab. de Materiais e Tratamento de Superficies. Lab. de Nanopropriedades Mecanicas

    2004-09-15

    The austenitic stainless steel embrittlement is usually present on sulphurous medium due to the hydrogen presence, resulting on cracks and corrosion on acid medium. Several researches carried out on the behaviour of hydrogenated stainless steel structures, had shown that the hydrogen induces superficial phase transformation during hydrogenation period and cracks formation after this period. These are due to the permeation of the hydrogen into the material, which is apprehended on preferential site, resulting on high pressure zones of molecular hydrogen. These zones may lead the crack formation, compromising the mechanical properties. There are few results on austenitic and super austenitic stainless steel, considering the transformations induced on welded unions. This work evaluates the cracks nucleation on welded unions of super austenitic stainless steel AISI 904L exposed to hydrogen rich environments and its relation to the reduction of material ductility. The samples were welded by the Mig/Mag process, followed by hydrogenation which were cathodic on sulfuric acid solution at room temperature. The results showed that the tested super austenitic stainless steel has a significant amount of cracks and no phase transformation has occurred after hydronization. (author)

  3. The optimization of FHT-based ACO-OFDM atmospheric laser communication system in terms of PAPR reduction

    Guo, Qiwen; Wei, Yiran; Duan, Yuning

    2013-08-01

    The application of orthogonal frequency division multiplexing (OFDM) in atmospheric laser communication is not as wildly as expected. This is should be owing to several problems rooted in OFDM system and the incompatibility between IM and OFDM. Aiming to analyze the major problems and propose optimized solutions, in the first part of this paper, we introduce the application of fast Hartley transform (FHT), as a suitable alternative to FFT, in asymmetrically clipped (AC) OFDM Atmospheric laser communication system. Then we demonstrate the problem of high PAPR embedded in such system. In the following part of this paper, we firstly review and analyze the performance of some standard methods, namely, Clipping, Companding, Selective Mapping (SLM), Partial Transmit Sequence (PTS), used to reduce the high peak to average power ratio (PAPR) caused by OFDM. And then we make some modifications on those methods so that they could be applied on DHT based AC-OFDM atmospheric laser communication system with more effectiveness. Finally, we propose and compare four different PAPR reduction techniques obtained by serialization of those modified methods. And by using Matlab simulation we demonstrate the feasibility of the proposed methods.

  4. Corrosion behavior of stainless steel in bio diesel production; Comportamento quanto a corrosao de acos inoxidaveis na producao do biodiesel

    Miranda, E.F. de [ArcelorMittal Sao Paulo Servicos, SP (Brazil); Moreira, M.C.; Lebrao, S.M.G. [Centro Universitario do Instituto Maua de Tecnologia, Sao Paulo, SP (Brazil)], e-mail: susana.lebrao@maua.br

    2010-07-01

    Biodiesel has become more attractive due to the benefits to the environment, mainly because it is a renewable resource. However, the main barrier to biodiesel is it cost. One factor which is charged to marketing is the use of stainless steel throughout the production line, the most used is AISI 304. To evaluate more economical stainless steels, weight loss and stress corrosion tests were performed on samples of AISI 304 and 439 in methanol PS X30% sodium methylate solution, crude soybean oil, glycerol and biodiesel for about two hundred and fifty days. The mass loss was negligible, and there was complete absence of pitting and stress corrosion cracking in all media studied, showing that both alloys are suitable for the manufacture of such equipment. (author)

  5. Evaluation of the carburized surface of steels with Magnetic Barkhausen Noise; Avaliacao de superficie cementada de acos com efeito Barkhausen

    Campos, M.F. de; Santos, R.; Silva, F.S. da; Ribeiro, S.B.; Lins, J.F.C., E-mail: mcampos@metal.eeimvr.uff.b [Universidade Federal Fluminense (PUVR/UFF), Volta Redonda, RJ (Brazil). Polo Universitario de Volta Redonda; Franco, F.A.; Padovese, L.R. [Universidade de Sao Paulo (EPUSP), SP (Brazil). Escola Politecnica

    2010-07-01

    Steels with different carbon content, 0.11%C and 0.48%C were submitted to a heat treatment for carburization in the surface. The samples were analyzed in the conditions: normalized, only carburized and carburized and quenched as received. The Magnetic Barkhausen Noise (MBN) was measured in all samples. A better understanding of the relation between microstructure and MBN is of large interest for nondestructive characterization. X-ray diffraction (XRD) has revealed large peak broadening for the samples carburized and quenched, which have martensite. This is due to the high density of dislocations and high internal stress in the martensite. It is also found that the MBN peaks are quite distinct for the samples with martensite, which present nanocrystalline structure. When martensite is present, domain rotation occurs more significantly, reducing the permeability and the MBN envelope signal intensity. MBN is a suitable method for non-destructive evaluation of the quality of the carburization process. (author)

  6. Reprocessamento de cateteres cardíacos: uma revisão Reuse of cardiac catheters: a review

    Silma Maria Cunha Pinheiro Ribeiro

    2006-09-01

    Full Text Available Os cateteres de hemodinâmica são amplamente reprocessados, principalmente em países em desenvolvimento, onde os custos da utilização desses insumos são altos. A literatura científica aponta a ausência de processos validados de limpeza e esterilização e é unânime a afirmação de que o reprocessamento provoca alterações na integridade física, química e funcional desses materiais. Dentro desse contexto, questionam-se quais as evidências publicadas sobre os danos provocados pelo reprocessamento dos cateteres de hemodinâmica? O objetivo é identificar as evidências científicas em relação aos efeitos do reprocessamento dos cateteres, do ponto de vista mecânico, físico, químico e biológico. Foi realizada uma pesquisa na base de dados Medline/Pubmed e LILACS, sem restrições de tempo, em inglês, português e espanhol, usando vocabulário controlado e não-controlado. Um total de 21 publicações foi analisado. Os artigos analisados apontam a ocorrência de alterações físicas, mecânicas e químicas. A limpeza e a esterilização dos cateteres não foi eficiente, tendo sido identificada a presença de debris e microrganismos ao final do processo. Vale ressaltar a importância dessas informações para a tomada de decisão em relação ao reprocessamento e reuso de cateteres de hemodinâmica.Hemodynamic catheters are widely reused mainly in developing countries where the cost of new devices is very high. Scientific publications point to an absence of validated cleaning and sterilization processes and there is a consensus that reusing these devices causes physical, chemical and funcional damage. So what is the evidence related to the use of this kind of catheter? The objective of this study is to identify the scientific evidence related to the effects of reprocessing. A search for publications in English, Portuguese and Spanish was performed in Medline/Pubmed and LILACS using Medical Subject Headings (MeSH terms and free terms without stipulating restraints on time. In total 21 papers were analized. It was found that there is commonly damage to the surface polymers as identified by eletronic microscopy. Failure in the cleaning and sterilization process was identified by the presence of debris and microrganisms at the end of the procedure. The results of this study are very important when choosing to reuse hemodynamic catheters.

  7. Reliability-Based Design Optimization for Crane Metallic Structure Using ACO and AFOSM Based on China Standards

    Xiaoning Fan

    2015-01-01

    Full Text Available The design optimization of crane metallic structures is of great significance in reducing their weight and cost. Although it is known that uncertainties in the loads, geometry, dimensions, and materials of crane metallic structures are inherent and inevitable and that deterministic structural optimization can lead to an unreliable structure in practical applications, little amount of research on these factors has been reported. This paper considers a sensitivity analysis of uncertain variables and constructs a reliability-based design optimization model of an overhead traveling crane metallic structure. An advanced first-order second-moment method is used to calculate the reliability indices of probabilistic constraints at each design point. An effective ant colony optimization with a mutation local search is developed to achieve the global optimal solution. By applying our reliability-based design optimization to a realistic crane structure, we demonstrate that, compared with the practical design and the deterministic design optimization, the proposed method could find the lighter structure weight while satisfying the deterministic and probabilistic stress, deflection, and stiffness constraints and is therefore both feasible and effective.

  8. Energy Efficient And Qos Aware Ant Colony Optimization (Eq-Aco Routing Protocol For Wireless Sensor Networks

    Devee Prasan.U

    2012-02-01

    Full Text Available Wireless sensor network (WSN is a collection of autonomous, tiny, large number of densely deployed sensor nodes; these sensor nodes are smart, effective which offers very powerful and versatile networking where traditional wired and wireless networking is unable to deploy.

  9. Recuperación retrospectiva de un archivo policíaco: el “Casellario Politico Centrale”

    Chiaretti, Alessandro

    2012-01-01

    The research illustrates utilization strategies of description standards and advanced technologies that are the basis of recovery ("recuperación retrospectiva") methodologies of archival finding aids, experienced in overcoming the problems associated with communicating and sharing resources. Considering interoperability, both technological and semantic, and long-term preservation of information as primary objectives of information systems, it is considered that recovery operations have to ...

  10. Colecistectomia videolaparoscópica em paciente submetido a transplante cardíaco Laparoscopic cholecystectomy in heart transplant patient

    Flávio Heuta Ivano

    2000-10-01

    Full Text Available Cardiac transplant has been performed with an increased frequency as the treatment for end-stage cardiac disease. Although cholelithiasis is more frequent in both pretransplant and posttransplant patients, no standard management approach exists. Pretransplant patients are well recognized for cardiac events, and posttransplant immunossupressed patients are at a considerable risk for septic complications. Because the first presentation of gallstones in this population is often acute cholecystitis, asymptomatic calculi cannot be considered benign and it seems reasonable to recommend pretransplant screening and posttransplant surveillance for gallstones. Prophylatic laparoscopic cholecistectomy should be undertaken in the stable patient to avoid the substantial mortality associated with postoperative acute cholecystitis and urgent cholecystectomy. In this case report we present a 44 year-old male with acute cholecystitis after cardiac transplantation who was submitted to a safe laparoscopic cholecystectomy one year and seven months later.

  11. Punciones repetidas de la arteria radial para cateterismo cardíaco Repeated radial artery puncture for cardiac catheterization

    Eduardo Magariños

    2007-06-01

    Full Text Available La punción percutánea de la arteria radial para la realización de procedimientos por cateterismo ha ganado aceptación debido a una eficacia similar a la obtenida con el acceso femoral. En el presente trabajo evaluamos los resultados obtenidos con la punción repetida de esta arteria. En un total de 182 accesos radiales se realizaron 17 punciones repetidas, y mediante ellas, 20 procedimientos (9 coronariografías y 11 angioplastias. Se obtuvo éxito del acceso en 15 punciones repetidas (88.2% y éxito del procedimiento en todos los casos cuando logramos éxito del acceso. Si bien el grupo es pequeño es suficiente para mostrar que la punción repetida de la arteria radial es factible y permite una alta tasa de éxito de los procedimientos con una disminución ostensible de las complicaciones locales.The radial artery approach for percutaneous cardiac interventions has gained worldwide acceptance due to the similar results obtained by the femoral artery access. In this paper, we report our experience with repeated puncture of the radial artery. One hundred and eighty two radial artery access procedures were performed, in 17 interventions the puncture was repeated once or twice, with a total of 20 therapeutic catheterizations (9 coronary angiographies, 11 angioplasties. There was no therapeutic failure through the radial approach but, we successfully gained access in 88.2% (15/17 of the re-interventions cases. Although an experience with a low number of cases, we had a very high successful therapeutic rate, and also a remarkable lowering of local complications, this shows the feasibility and potential of this technique.

  12. Caracterización funcional de cotransportador Na+HCO3- cardíaco

    De Giusti, Verónica Celeste

    2010-01-01

    El objetivo general del presente estudio de Tesis es la “Caracterización funcional del cotransportador Na+/HCO3- (NBC) cardíaco”, investigando la implicancia de sus diferentes isoformas en la fisiología cardíaca y esclareciendo el papel que cumple la Angiotensina II (Ang II) en la modulación de su actividad. Para ello se utilizaron miocitos ventriculares de gato adulto en los cuales se midió el pH intracelular (pHi) por epifluorescencia y se realizaron registros de potenciales de acción (PA) ...

  13. A novel tripodal colorimetric and fluorescence "turn on" chemosensor for AcO(-) and F(-) anions in CH3CN.

    Alici, Onder

    2016-10-01

    A novel chemosensor, 3',3‴,3‴″-(((nitrilotris(ethane-2,1-diyl))tris(azanylylidene))tris(methanylylidene))tris(4-hydroxy-4'-biphenylcarbonitrile) (L) was synthesized and characterized by the combination of (1)H,(13)C, APT, COSY NMR, FT-IR, and elemental analysis. The behavior of the receptor (L) toward different anions was investigated using UV-visible and fluorescence spectroscopy. The receptor (L) indicated an efficient colorimetric "naked-eye" and "turn on" fluorescent response for fluoride and acetate in CH3CN, respectively. PMID:27258686

  14. 76 FR 58007 - Privacy Act of 1974; Report of a New System of Records

    2011-09-19

    ... ACO name and address (which could be the home address of a key leader or manager of the ACO); ACO... the U.S. Department of Justice. SYSTEM MANAGER AND ADDRESS: Director, Performance-Based Payment...

  15. Monitorização de transplante cardíaco usando análises do eletrograma intracavitário

    BROFMAN Paulo Roberto S.

    1997-01-01

    Full Text Available Uma série de registros do eletrograma intracavitário tem sido utilizada para monitorização não invasiva da rejeição em pacientes transplantados usando um marcapasso de dupla câmara e eletrodos endocavitários revestidos com estrutura fractal. Os sinais têm sido avaliados usando o sistema CHARM (Computerized Heart Acute Rejection Monitoring _ sistema computadorizado para monitorização da rejeição cardíaca aguda. Os relatórios obtidos com este sistema contêm curvas com parâmetros sensíveis à rejeição, que demonstram uma boa correlação com a clínica e os resultados das biópsias convencionais. A monitorização a longo prazo, usando estas análises, mostrou ser uma ferramenta valiosa no acompanhamento destes pacientes.

  16. Diseño e implementación de un juego serio de entrenamiento quirúrgico cardíaco

    Pedreira Estabridis, Javier Ignacio

    2014-01-01

    De todas las patologías cardíacas,este proyecto se centra en las que afectan a la válvula mitral, que se encala mayor parte de países desarrollados del primer mundo. Este proyecto se centra en las que afectan a la válvula mitral, que se encarga de regular el paso de la sangre entre la aurícula y el ventrículo izquierdo. El mecanismo de la válvula es sencillo, cuando la aurícula izquierda se llena de sangre durante el movimiento. ticar en un entorno de pruebas, con el objetivo de reduci...

  17. Carbon Monitoring System Flux Estimation and Attribution: Impact of ACOS-GOSAT X(CO2) Sampling on the Inference of Terrestrial Biospheric Sources and Sinks

    Liu, Junjie; Bowman, Kevin W.; Lee, Memong; Henze, David K.; Bousserez, Nicolas; Brix, Holger; Collatz, G. James; Menemenlis, Dimitris; Ott, Lesley; Pawson, Steven; Jones, Dylan; Nassar, Ray

    2014-01-01

    Using an Observing System Simulation Experiment (OSSE), we investigate the impact of JAXA Greenhouse gases Observing SATellite 'IBUKI' (GOSAT) sampling on the estimation of terrestrial biospheric flux with the NASA Carbon Monitoring System Flux (CMS-Flux) estimation and attribution strategy. The simulated observations in the OSSE use the actual column carbon dioxide (X(CO2)) b2.9 retrieval sensitivity and quality control for the year 2010 processed through the Atmospheric CO2 Observations from Space algorithm. CMS-Flux is a variational inversion system that uses the GEOS-Chem forward and adjoint model forced by a suite of observationally constrained fluxes from ocean, land and anthropogenic models. We investigate the impact of GOSAT sampling on flux estimation in two aspects: 1) random error uncertainty reduction and 2) the global and regional bias in posterior flux resulted from the spatiotemporally biased GOSAT sampling. Based on Monte Carlo calculations, we find that global average flux uncertainty reduction ranges from 25% in September to 60% in July. When aggregated to the 11 land regions designated by the phase 3 of the Atmospheric Tracer Transport Model Intercomparison Project, the annual mean uncertainty reduction ranges from 10% over North American boreal to 38% over South American temperate, which is driven by observational coverage and the magnitude of prior flux uncertainty. The uncertainty reduction over the South American tropical region is 30%, even with sparse observation coverage. We show that this reduction results from the large prior flux uncertainty and the impact of non-local observations. Given the assumed prior error statistics, the degree of freedom for signal is approx.1132 for 1-yr of the 74 055 GOSAT X(CO2) observations, which indicates that GOSAT provides approx.1132 independent pieces of information about surface fluxes. We quantify the impact of GOSAT's spatiotemporally sampling on the posterior flux, and find that a 0.7 gigatons of carbon bias in the global annual posterior flux resulted from the seasonally and diurnally biased sampling when using a diagonal prior flux error covariance.

  18. OUTCOME ANALYSIS OF POSTERIOR STABILIZATION OF THOR ACO- LUMBAR SPINE FRACTURES IN A RURAL TERTIARY CARE CEN TRE –AN EXPERIENCE

    Prasanta Kumar

    2013-05-01

    Full Text Available ABSTRACT: Thirty five patient with unstable fractures of the lower thoracic and lumbar spine managed uniformly with Hartshill fixation and subla minar wiring were analyzed. On admission, 18 patients had complete neurologic deficit and 17 had incomplete lesions. The neurologic recovery and functional activities were assessed after an averag e follow up for 20.4 months. Improvement of neural function was seen in 71 % patients. Positive correlation was found between the level of injury and Frankel grades. The cord lesions tended to demo nstrate more severe neurologic deficit than cauda equina lesions. A component of dislocation to the injury also resulted in a more severe neural deficit. The complications were minor. Stable fixat ion of thoracolumbar spine fractures was helpful in decreasing hospital stay and recumbency period, the reby facilitating early rehabilitation of the spine injured patients.

  19. Relativistic actions for bound-states and applications in the meson spectroscopy; Acoes relativisticas para estados ligados e aplicacoes na espectroscopia de mesons

    Silva Carvalho, Hendly da

    1991-08-01

    We study relativistic equations for bound states of two-body systems using Dirac`s constraint formalism and supersymmetry. The two-body system can be of spinless particles, one of them spinning and the other one spinless, or both of them spinning. The interaction is described by scalar, timelike four-vector and spacelike four-vector potentials under Lorentz transformations. As an application we use the relativistic wave equation for two scalar particles and calculate the mass spectra of the mesons treating them as spinless quark-antiquark bound states. The interaction potential in this case is a convenient adaptation of the potential employed in non-relativistic calculations. Finally, we compare our results with more recent experimental data and with theoretical results obtained with the same potential used by us but with a non-relativistic wave equation. We also compare our results with results obtained with the relativistic wave equation but with a different interaction potential. (author). 38 refs, 9 figs, 8 tabs.

  20. Isolamento, caracterização, ativação e diferenciação em linhagens mesenquimais de pericitos cardíacos humanos

    de Aguiar, Alessandra Melo

    2012-01-01

    Resumo: Células residentes teciduais são atualmente identificadas como populações de células progenitoras promissoras para terapias celulares. Neste trabalho, foi realizado o isolamento de células cardíacas humanas que expressam a enzima fosfatase alcalina, e estas células apresentaram características de célula-tronco mesenquimais (CTM). Foram utilizadas amostras de 24 doadores cadavéricos provenientes do Banco de Homoenxertos Humanos da Santa Casa de Misericórdia de Curitiba. O tempo médio d...

  1. Efeito da eletrolipólise na gordura abdominal em doentes cardíacos - fase manutenção

    Miranda, Ana

    2012-01-01

    Objective: Verify if electrolipolysis could help the Cardiac Rehabilitation decreasing the abdominal’s fat in people with Cardiovascular Disease. Methods: six individuals of both sexes, from “Centro Clínico de Gaia” Cardiac Rehabilitation Program, were randomized in two groups: the control (CG) (n=3) and the experimental group (EG) (n=3). The EG had 8 session (twice a week) of electrolipolysis, through microcurrent, during 30 minutes and before the Cardiac Rehabilitation classe...

  2. Expanded austenite in nitrided layers deposited on austenitic and super austenitic stainless steel grades; Analise da austenita expandida em camadas nitretadas em acos inoxidaveis austeniticos e superaustenitico

    Casteletti, L.C.; Fernandes, F.A.P.; Heck, S.C. [Universidade de Sao Paulo (EESC/USP), Sao Carlos, SP (Brazil). Escola de Engenharia. Dept. de Engenharia de Materais, Aeronautica e Automobilistica; Oliveira, A.M. [Instituto de Educacao, Ciencia e Tecnologia do Maranhao (IFMA), Sao Luis, MA (Brazil); Gallego, J., E-mail: gallego@dem.feis.unesp.b [UNESP, Ilha Solteira, SP (Brazil). Dept. Engenharia Mecanica

    2010-07-01

    In this work nitrided layers deposited on austenitic and super austenitic stainless steels were analyzed through optical microscopy and X-rays diffraction analysis (XRD). It was observed that the formation of N supersaturated phase, called expanded austenite, has promoted significant increment of hardness (> 1000HV). XRD results have indicated the anomalous displacement of the diffracted peaks, in comparison with the normal austenite. This behavior, combined with peaks broadening, it was analyzed in different nitriding temperatures which results showed good agreement with the literature. (author)

  3. Susceptibility to intergranular corrosion of welded joints of Super 13Cr stainless steels; Suscetibilidade a corrosao intergranular de juntas soldadas de acos inoxidaveis Super 13Cr

    Rovere, C.A.D.; Ribeiro, C.R.; Kuri, S.E. [Universidade Federal de Sao Carlos (UFSCar), Sao Carlos, SP (Brazil). Dept. de Engenharia de Materiais], e-mail: dellarovere@superig.com.br

    2006-07-01

    The susceptibility to intergranular corrosion was evaluated in distinct regions of radial friction welded joints of super 13 Cr martensitic stainless steel, using the electrochemical potentiokinetic reactivation test in the double loop version (DL-EPR). The thermal cycle and the plastic deformation associated to radial friction process alter significantly the microstructure of heat affected zone and thermo-mechanically affected zone, fact that causes a low value in the I{sub r}/I{sub a} ratio of these regions in comparison to the quenching and tempering condition of the base metal. (author)

  4. Weldability evaluation of special stainless steels for utilization in petroleum industry; Avaliacao da soldabilidade de acos inoxidaveis especiais a ser utilizados na industria do petroleo

    Cortes Paredes, Ramon S. [Parana Univ., Curitiba, PR (Brazil)]. E-mail: ramon@demec.ufpr.br; Borsato, Karin Soldatelli [Pontificia Univ. Catolica do Parana, Curitiba, PR (Brazil); Bernardini, Pedro Amadeo Nanneti [Santa Catarina Univ., Florianopolis, SC (Brazil); Villanueva Aguila, Jaime [Universidade de Tarapaca (UTA), Arica (Chile)

    2003-07-01

    A weldability study of super austenitic stainless steel AISI 904L type 25 Ni. 20 Cr, with Mo, Cu and duplex stainless steel UNS S31803 additions is made. The higher mechanical properties and corrosion resistance of duplex stainless steels, when compared to other kinds of stainless steels, have increased the attention of different industrial areas. According to literature, AISI 904L stainless steel is sensitive to solidification and liquation cracking during welding. The main microstructural features, as well as mechanical properties of duplex stainless steels, can be modify when submitted to multiple thermal cycles , such as happen during welding process. Samples have been prepared and welded by two welding processes: coated electrodes and semi-automatic MIG. The objective was to evaluate the cracking sensitiveness of super austenitic steels . For duplex steels the aim was to research the welding process influence for tubular wire in the microstructure and mechanical properties of a 25 mm plate, which are considered of great thickness. In AISI 904L it has not been observed any solidification cracking in the structure in the two welding processes that were studied. However, cracking of liquation in the affected thermal zone has been observed. In duplex steels the use of different thermal cycles showed variation of delta ferrite in the structure of solidification and variation of ferrite grain size in the ZTA. The formation of nitrate and secondary austenitic was also observed, which results in a proportional hardness increase . The mechanical and microstructure characterization data of those two stainless steels are presented. (author)

  5. Sentimientos y emociones de la persona sometida a cateterismo card??aco = Feelings and emotions of the person undergoing cardiac catheterization.

    Candelero Fidalgo, Marcelino

    2016-01-01

    El cateterismo cardiaco es la t??cnica de elecci??n tanto en el diagn??stico como en el tratamiento de la enfermedad coronaria. La realizaci??n del mismo va a desencadenar en el paciente una serie de sentimientos y emociones que influir??n en su proceso de recuperaci??n. Ante este problema, se plantea la pregunta sobre la realidad sujeta a estudio: ??C??mo viven esas personas este tipo de abordaje? ??Qu?? sienten? As?? el objetivo es principal: - Conocer los sentimientos ...

  6. Grain boundary character distribution in a hot rolled 316 L stainless steel; Distribuicao de tipos de contornos de grao em um aco inoxidavel 316L laminado a quente

    Lopes, L.C.R. [Rio Grande do Sul Univ., Porto Alegre, RS (Brazil). Dept. de Metalurgia; Thomson, C.B. [Wales Univ., Swansea (United Kingdom)

    1995-12-31

    The texture and the grain boundary character distribution of a 316 L stainless steel under hot rolled condition have been studied. Electron back-scatter diffraction technique associated to the scanning electron microscopy is used to determine the crystallographic orientation of grains individually. The material presented a random texture. However, the misorientation axis distribution represented by an inverse pole figure showed a non-random distribution with a high proportion <111> misorientation axis. The disorientation angle distribution indicates a proportion of about 60% of boundaries with 60 deg C misorientation angle. A 25% proportion of CSL interfaces of {Sigma} = 3 type was found 17 refs., 9 figs., 2 tabs.

  7. New cyclometallated precursors of unsubstituted N-phenylpyrazole [{Pd(phpz)(μ-X)}2] (X = AcO or OH) and study of their reactivity towards selected ligands.

    Serrano, José Luis; García, Luis; Pérez, José; Pérez, Eduardo; Galiana, José Miguel; García, Joaquín; Martínez, Marina; Sánchez, Gregorio; da Silva, Ivan

    2011-01-01

    A new acetate-bridged dinuclear palladacycle with unsubstituted N-phenylpyrazole [{Pd(phpz)(μ-AcO)}(2)] 1 has been isolated and characterised, including an X-ray diffraction study. A survey of the Cambridge Structural Database (CSD) v. 5.31 looking for analogous dimeric C^N cyclopalladated complexes has been done, exploring the incidence of cisoid/transoid arrangements, the preferred conformation of the eight-membered ring formed in the double bridge, the Pd-Pd distance and the main factors that affect it. The reaction of 1 with NBu(4)OH yielded [{Pd(phpz)(μ-OH)}(2)] 2 that has shown to be a complementary precursor of 1 in terms of acid/base reactivity. In this sense, both 1 and 2 are also well differentiated from halide precursors available to date. The preparation of selected complexes with potential applications in several fields, [Pd(phpz)(O^N)] O^N = N-p-chlorophenylsalycilaldiminate (N-pClsal) 3, picolinic acid (pic) 4; 8-hydroxiquinolinate (oxin) 5; 2-pyrrole-carboxaldeydate (2-pcal) 6, [Pd(phpz)(O^O)] O^O = salycilaldehydate (sal) 7 acetylacetonate (acac) 8, [{Pd(phpz)(μ-N^S)}(2)] N^S = 2-mercapto-1-methylimidazolate (SMeimz) 11; [{Pd(phpz)(μ-N^O)}(2)] N^O = succinimidate (succ) 12; [{Pd(phpz)(μ-N^N)}(2)] (N^N = pyrazolate (pz) 13, has been achieved using 1 or 2 as starting materials in acid/base reactions. Dithiocarbamate [Pd(phpz)(S(2)CNEt(2))] 9 and dithiophosphate [Pd(phpz){S(S)P(OEt)(2)}] 10 derivatives have been synthesised in related reactions, and the reactivity of 1 against neutral phosphine ligands has also been tested with the preparation of [Pd(phpz)(AcO)(PPh(3))] 14. The crystal structures of compounds 7, 9, 11, 12 and 13 (this one obtained from a powder sample using synchrotron radiation) have also been established, and together with 1 are the first examples of complexes containing unsubstituted N-phenylpyrazole as cyclometallated backbone that have been deposited to date on the Cambridge Structural Database. PMID:21060953

  8. Análise do sinal cardíaco ECG através da técnica SVD

    Rodrigues, Celso Eduardo Real

    2014-01-01

    This work arises in the scope of the Electromedicine field, an increasingly influential component of Electrical Engineering, and one which is in constant development, where innovation and the development and application of new technologies are of critical importance. The goal of this project is the in-depth study of the applications of the SVD (Singular Value Decomposition) technique, a powerful mathematical tool that allows the manipulation of signals using matrix decomposition, in the sp...

  9. Network Traffic Prediction Based on Neural Network Optimized by ACO%蚁群算法优化RBF神经网络的网络流量预测

    廖金权

    2012-01-01

    Traditional RBF neural network in the forecasting process of the network traffic convergence is slow, prone to local optima and other shortcomings, resulting in low prediction accuracy and difficult problems. In order to improve the prediction accuracy of network traffic, network traffic prediction method for an ant colony algorithm to optimize the parameters of RBF neural network. Ant colony algorithm for training RBF neural network center and the width of the basis functions to speed up the convergence, simplifying the network structure to improve the generalization capability of RBF neural networks, and optimized RBF neural network to predict the network traffic, to prevent local optimum to appear. The experimental results show that relative to the commonly used BP neural network traffic prediction model, model predictions more accurate, can be well described by the variation of the network flow. With good generalization ability, good stability and a certain practical value in the prediction of network traffic.%传统RBF神经网络在网络流量预测过程中存在收敛速度慢、极易出现局部最优等缺点,从而导致预测精度低.采用蚁群算法优化RBF神经网络参数来进行网络流量预测.利用蚁群优化算法来训练RBF神经网络的基函数宽度和中心,简化网络结构,加快收敛速度,防止局部最优的出现,改善RBF神经网络的泛化能力.实验结果表明,相对于GA-RBF以及PSO-RBF流量预测模型,模型预测准确度更高,能够很好地描述网络流的变化规律.具有泛化能力强、稳定性良好的特点,在网络流量预测中有一定的实用价值.

  10. Cardiac markers: profile in rats experimentally infected with Toxocara canis Marcadores cardíacos: perfil em ratos infectados experimentalmente com Toxocara canis

    Cecília Braga Laposy

    2012-09-01

    Full Text Available The aim of this study was to evaluate the profile of the enzymes creatine kinase (CK, creatine kinase MB (CK-MB and lactate dehydrogenase (LDH in Wistar rats infected with 250 (GI, n = 24 or 1000 (GII, n = 24 Toxocara canis eggs. Animals were evaluated on days 7, 15, 30, 60, 120 and 180 post-infection (DPI. Only the GI rats showed an increase in CK and CK-MB, at 15 and 30 DPI, respectively. Anti-Toxocara spp. antibodies were detected by ELISA in infected animals. Despite of the presence of eosinophilic infiltrate in the heart of three infected animals, none larva was recovered from the organ neither by acid digestion nor by Baermann procedure. Eosinophilia was observed in both groups but there was no significant difference in the eosinophil counts between GI and GII (p = 0.2239. It is possible to consider that cardiac lesion is an eventual finding in murine model for toxocariasis.O objetivo do presente estudo foi avaliar o perfil das enzimas creatinoquinase (CK, creatinoquinase-MB (CK-MB e lactato desidrogenase (LDH em ratos Wistar infectados com 250 (GI, n = 24 ou 1000 (GII, n = 24 ovos de Toxocara canis. Os animais foram avaliados nos dias 7, 15, 30, 60, 120 e 180 pós-infecção (DPI. Observou-se que apenas os animais do GI apresentaram aumento da atividade de CK e CK-MB aos 15 e 30 DPI, respectivamente. Anticorpos anti-T. canis foram detectados por ELISA nos animais infectados. Apesar da presença de infiltrado eosinofílico em três animais infectados, nenhuma larva foi recuperada do coração pela digestão ácida ou pela técnica de Baermann. Eosinofilia foi observada em todos os momentos em GI e GII, sem diferença significativa entre os grupos (p = 0,2239. Pode-se considerar que as lesões cardíacas foram um achado eventual no modelo murino para toxocaríase.

  11. Characterization of steel grit recovered from ornamental rocks waste by magnetic separation; Caracterizacao da granalha de aco recuperada do residuo de rochas ornamentais por separacao magnetica

    Junca, E.; Telles, V.B.; Rodrigues, G.F.; Oliveira, J.R. de; Tenorio, J.A.S., E-mail: eduardojunca@gmail.co [Universidade de Sao Paulo (USP), SP (Brazil). Dept. de Engenharia Metalurgica e de Materiais; Instituto Federal de Ciencia e Tecnologia do Espirito Santo (IFES), Vitoria, ES (Brazil)

    2010-07-01

    The aim of this work is characterization of steel grit recovered from ornamental rock waste by magnetic separation. The magnetic separation was realized in three steps: first, using a high intensity wet magnetic separator, which used only the remaining magnetic field of equipment. In the second step, the magnetic material obtained in the first phase was subjected to a new manual magnetic separation using rare earth magnets. In a third step, magnetic material obtained with rare earth magnets was subjected to manual magnetic separation using ferrite magnets. After the magnetic separation, the material was sent to characterization which was obtained by chemical analysis, scanning electron microscopy, X-ray diffraction and size analysis. The size analysis showed that the concentrate range from 0,5 to 563,67 {mu}m with 4 wt.% over 100 {mu}m and content metallic iron of 93 wt%. (author)

  12. Hydrogen embrittlement in superaustenitic stainless steels welded unions in sulfuric acid; Fragilizacao por hidrogenio em juntas soldadas de acos inoxidaveis superausteniticos em acido sulfurico

    Berthier, T. [Parana Univ., Curitiba, PR (Brazil). Lab. de Materiais e Tratamento de Superficies (LaMaTS)]. E-mail: thiana@demec.ufpr.br; Kuromoto, N.K. [Parana Univ., Curitiba, PR (Brazil). Lab. de Nanopropriedades Mecanicas; Paredes, R.S.C. [Instituto de Tecnologia para o Desenvolvimento (LACTEC), Curitiba, PR (Brazil)

    2003-07-01

    The embrittlement of the austenitic stainless steel by hydrogen has been known for more than four decades. Researches done into the behavior of the hydrogenated homogeneous structures, under cathodic charging at room temperature, have shown that the hydrogen induces phase transformations and nucleation of retarded superficial cracks during the outgassing which is followed by the end of the hydrogenation. The results obtained upon austenitic and superaustenitic stainless steels are few considering the changes produced in welded unions. The aim of this work is to evaluate mechanical properties of material and its relation to the nucleation of the cracks in the austenitic steels welds type AISI 904L submitted to hydrogenated solutions. The samples have been welded through the process MIG/MAG; the hydrogenation has been made catholically in a sulfuric acid solution of 1N, with variable time of 1 to 4 hours at the room temperature. An anode of platinum in and density of current 1000 A/m{sup 2} has been used. The outgassing has occurred at the room temperature. Many retarded superficial cracks with different morphologies have been observed. Regarding the hardness measure, major alterations in all the regions of the sample have not been noticed. (author)

  13. Segmentación automática de estudios PET cardíacos con ¹³NH_3 basada en correlación iterativa

    Mateos-Pérez, José M.; García-Villalba, Carmen; Abella, Mónica; Desco, Manuel; Vaquero, Juan José

    2010-01-01

    Actas de: XXVIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB 2010). Madrid, 24-26 de noviembre de 2010. La obtención de la función de entrada en estudios dinámicos de corazón a partir de la imagen PET se realiza habitualmente mediante la selección previa de una región de interés (ROI) o utilizando procedimientos de análisis factorial para encontrar aquellas curvas actividad/tiempo que mejor se adaptan a la función de entrada. En este trabajo se presenta un método...

  14. Liberación de endotelina-1 por angiotensina ll en miocitos cardíacos aislados Angiotensin II-induced endothelin-1 release in cardiac myocytes

    María C. Villa-Abrille; Cingolani, Horacio E; Carolina D. Garciarena; Ennis, Irene L.; Aiello, Ernesto A.

    2006-01-01

    Muchos de los efectos de la angiotensina II (Ang II) son mediados en realidad por la acción de endotelina (ET) endógena liberada y/o producida en respuesta a la Ang II. En este trabajo evaluamos la interacción Ang II/ET-1, sus consecuencias en la contractilidad cardíaca y el papel de las especies reactivas del oxígeno (EROs). Se usaron cardiomiocitos aislados de gato. La Ang II, 1 nM, produjo un efecto inotrópico positivo (EIP) de 31.8±3.8% que fue cancelado por inhibición de los receptores A...

  15. Liberación de endotelina-1 por angiotensina ll en miocitos cardíacos aislados Angiotensin II-induced endothelin-1 release in cardiac myocytes

    María C. Villa-Abrille

    2006-06-01

    Full Text Available Muchos de los efectos de la angiotensina II (Ang II son mediados en realidad por la acción de endotelina (ET endógena liberada y/o producida en respuesta a la Ang II. En este trabajo evaluamos la interacción Ang II/ET-1, sus consecuencias en la contractilidad cardíaca y el papel de las especies reactivas del oxígeno (EROs. Se usaron cardiomiocitos aislados de gato. La Ang II, 1 nM, produjo un efecto inotrópico positivo (EIP de 31.8±3.8% que fue cancelado por inhibición de los receptores AT1, de los receptores de ET, del intercambiador Na+/H+ (NHE, del modo inverso del intercambiador Na+/Ca2+ (NCX o por el secuestro de EROs. La Ang II, 100 nM, produjo un EIP de 70.5±7.6% que fue cancelado por inhibición de los receptores AT1 y bloqueado en parte por inhibición de los receptores de ET, del NHE, del modo inverso del NCX o por el secuestro de EROs. La Ang II, 1 nM, incrementó el ARNm de la preproET-1 lo cual fue anulado por el bloqueo de los receptores AT1. Los resultados permiten concluir que el EIP de la Ang II es debido a la acción de la ET-1 endógena liberada/formada por la Ang II. La ET-1 produce: estimulación del NHE, activación del modo inverso del NCX y un consecuente EIP. Dentro de esta cascada también participarían los EROs.Many of the effects thought to be due to angiotensin II (Ang II are due to the release/formation of endothelin (ET. We tested whether Ang II elicits its positive inotropic effect (PIE by the action of endogenous ET-1 and the role played by the reactive oxygen species (ROS in this mechanism. Experiments were performed in cat isolated ventricular myocytes in which sarcomere shortening (SS was measured to asses contractility after pharmacological interventions and the effect of Ang II on inotropism were analyzed. Ang II 1 nM increased SS by 31.8±3.8% (p<0.05. This PIE was cancelled by AT1 receptor blockade, by ET-1 receptors blockade, by Na+/H+ exchanger (NHE inhibition, by reverse mode Na+/Ca2+ exchanger (NCX blockade or by ROS scavenging. Ang II 100 nM increases SS by 70.5±7.6% (p<0.05. This PIE was completely abolished by AT1 receptors blockade and were partially bocked by ET-1 receptors blockade, by NHE inhibition, by reverse mode NCX blockade or by ROS scavenging. Ang II increased preproET-1 mRNA, effect that was blunted by AT1 receptors blockade. We conclude that Ang II induces (through its AT1 receptor release/formation of ET-1, which acting in autocrine fashion on ET receptors of the isolated myocytes increases inotropism through NHE stimulation and NCX reverse mode activation. The participation of ROS is involved is this chain of events.

  16. Prevalencia de patrones electrocardiográficos tipo Brugada en un centro de monitoreo cardíaco transtelefónico en El Salvador

    Hugo Alberto Abrego

    2006-05-01

    Full Text Available Introducción: Desde que se definieron los criterios que permiten diagnosticar el síndrome de Brugada, se han realizado varios estudios para determinar la prevalencia en el electrocardiograma (ECG de los pacientes con esta enfermedad. El objetivo de esta investigación fue determinar la prevalencia de los distintos patrones electrocardiográficos tipo Brugada (PETB en una población con acceso a monitoreo electrocardiográfico transtelefónico en El Salvador. Métodos: Todos los ECGs recibidos desde el 1/1/2002 hasta el 1/12/2004 en un centro de monitoreo transtelefónico fueron analizados por 2 cardiólogos de manera independiente. Los pertenecientes a pacientes a quienes se les diagnosticó enfermedad cardiovascular estructural y los de quienes tomaban fármacos de acción cardiovascular fueron excluidos. Resultados: De un total de 11669 ECGs de igual número de pacientes, algún PETB se encontró en 81 pacientes (0.7%. El promedio de edad de los pacientes fue de 36.4 ± 15.4 años; 64.6% de ellos eran masculinos. En 5 pacientes (6,17% se encontró el patrón tipo 1, todos estaban asintomáticos y en 1 se colocó un cardiodesfibrilador implantable por tener arritmia ventricular maligna inducible. El patrón tipo 2 fue el más frecuente (59 pacientes, 72,83% y solo se encontraron 17 pacientes con patrón tipo 3 (20,98%, todos asintomáticos. Conclusión: El electrocardiograma con PETB no es raro en esta población de El Salvador. Hay aproximadamente 1 PETB por cada 144 individuos y 1 caso de PETB tipo 1 por cada 2334 individuos de consulta general.Aim: Since the diagnostic criteria for the Brugada syndrome were defined, several studies have been made to calculate the electrocardiographic prevalence of this disease. The objective of this study was to define the prevalence of the different Brugada-type patterns in a population with access to transtelephonic electrocardiographic monitoring in El Salvador. Methods: All the electrocardiograms (ECG received via transtelephonic monitoring at our center between 1/1/2002 and 1/12/2004 were independently analyzed by 2 cardiologists. Results: Alter the exclusion of patients with structural cardiovascular disease, some pattern of Brugada-type ECG was found in 1 patients (0,7% out of 1166 ECGs from the same number of patients. Average age was 36.4 ± 15.4 years; 64.66 of the patients were male and 35.4% were female. In 5 patients Type 1 pattern was identified (6,17%, none of them had symptoms but an automatic cardioverter defibrillator was implanted in 1 of them because of inducible malignant ventricular arrhytmia. Type 2 was the most frequently found (59 cases, 72,83 and only 17 patients (20,98% were found to have a Type 3 pattern, all of them were free of symptoms. Conclusion The Brugada-like ECG is not infrequent in this population from El Salvador. There is a Brugada-type pattern for every 144 patients and one case of Type 1 pattern for every 2334 patients of general consultation.

  17. Study of corrosive effect of oil in super duplex stainless steels; Estudo do efeito corrosivo do petroleo em acos super duplex

    Gusmao, E.F.; Azambuja, V.M. [IFES, Coordenadoria de Metalurgia, Vitoria, ES (Brazil); Santos, D.S. [Universidade Federal do Rio de Janeiro (PEMM/COPPE/UFRJ), RJ (Brazil). Pos-Graduacao em Engenharia Metalurgica e de Materiais

    2010-07-01

    The super duplex stainless steel was exposed in an environment at 75 degree C with oil for days, weeks and month to observe the change in mass. The corrosion leads to loss of weight of material which could harm the economy of a company, as this will have to stop production to replace the corroded part. Hence the great importance of studies on ways to mitigate the corrosion. There was a chemical attack by the reagent Behara and testing to study the quality of the protective coating after the tests with oil by electrochemical impedance. (author)

  18. Quantificação da complexidade do ritmo cardíaco usando o método da Multiscale Entropy

    Pires, Tiago Marques

    2011-01-01

    Dissertação para obtenção do Grau de Mestre em Engenharia Biomédica Uma forma de aumentar o nosso conhecimento sobre os princípios fundamentais de funcionamento dos sistemas de controlo biológicos é através da análise da dinâmica dos sinais por eles produzidos em condições normais, patológicas e em resposta a estímulos específicos. Porém, a maioria destes sinais desafiam as técnicas tradicionais de processamento de sinal devido a propriedades como a não estacionariedade, não linearidade...

  19. Estudo sobre a prática do origami em pacientes cardíacos internados no Hospital São Paulo

    Sandra Midori Kuwahara Sasaki

    2012-06-01

    Full Text Available Introdução: Origami é uma arte milenar japonesa traduzida como dobradura de papel, ori significa dobrar e gami, papel. Este trabalho vem sendo utilizado com freqüência nos hospitais por ser uma atividade de baixo custo que nos remete a algumas lendas e histórias envolvendo o restabelecimento da doença. Objetivo: Compreender os efeitos do aprendizado da técnica do origami e analisar as representações simbólicas do pássaro tsuru. Método: A pesquisa teve uma abordagem qualitativa, exploratória e descritiva. Participaram 19 pacientes internados na enfermaria de cardiologia do Hospital São Paulo, com idade entre 24 e 65 anos, que aprenderam a técnica do origami e confeccionaram o pássaro tsuru. Em seguida, responderam um questionário sobre as percepções e sentimentos que afloraram na realização da atividade. Para a análise de conteúdo, utilizamos a técnica da análise temática. A análise simbólica dos depoimentos teve como base o referencial teórico da Psicologia Analítica de Jung. Resultados: Identificamos as seguintes categorias: Categoria 1- O origami como uma via de acesso ao estado meditativo. Categoria 2 - Simbolismos do pássaro tsuru. Categoria 3- O doente crônico no processo de individuação. Conclusão: a confecção do origami representou para os pacientes a manifestação de sentimentos e sensações associados ao estado meditativo. A estrutura do origami e seu caráter ritualístico e mandálico possuem semelhanças com o “artifício de autofocalização” (âncora relatado nas práticas meditativas. O pássaro tsuru foi representado como símbolo da paz, liberdade e vida, despertando o paciente a olhar para si mesmo, refletindo, assim, sobre o adoecer nesse momento de sua existência. Consideramos que o trabalho com o origami é um recurso que pode auxiliar o paciente a elaborar o processo de adoecimento. Este recurso lúdico também criou um espaço de integração entre o paciente, a equipe, os familiares e o ambiente hospitalar, favorecendo a humanização do cuidado na área da saúde.

  20. Modification and characterization of the AISI 410 martensitic stainless steels surface; Modificacao e caracterizacao da superficie do aco inoxidavel martensitico AISI 410

    Bincoleto, A.V.L. [Universidade Federal de Sao Carlos (PPG-CEM/UFSCar), SP (Brazil). Programa de Pos-Graduacao em Ciencia e Engenharia de Materiais; Nascente, P.A.P. [Universidade Federal de Sao Carlos (DEMa/UFSCar), SP (Brazil). Dept. de Engenharia de Materiais

    2010-07-01

    Steam turbines are used in the generation of more than half the electric energy produced in the world nowadays. It is important the study which aims to improve the efficiency by means of the optimization of leaks and of the aerodynamic profiles, as well as to maintain the integrity of the components. The martensitic stainless steels are widely employed due to the combination of their good mechanical properties with higher corrosion resistance. However, their lower wear resistance and their poor tribological behavior limit their use, since they decrease the component life time. In order to evaluate the improvement in the performance of the AISI 410 stainless steel, several process of surface modification were employed. Five samples were produced: the first one was not treated, the second one received liquid nitriding, the third, gas nitriding, the forth, thermal aspersion of tungsten carbide, and the fifth, boronizing. The samples were characterized by optical microscopy, surface microhardness, and X-ray diffractometry. (author)

  1. Evaluation to a long term remediation actions after Goiania radiological accident; Avaliacao a longo prazo das acoes de remediacao apos o acidente radiologico de Goiania

    Rochedo, Elaine R.R.; Rio, Monica A. Pires do; Coutinho, Celia M.C.; Acar, Maria E.D.; Romeiro, Carlos H. [Instituto de Radioprotecao e Dosimetria (IRD), Rio de Janeiro, RJ (Brazil)

    2000-07-01

    Ten years after the Goiania radiological accident, the results obtained by the IRD Environmental Monitoring Program are compared to the values adopted for establishing the intervention levels at the time of the accident occurrence (1987), and to the values of the parameters obtained by European countries, after the Chernobyl accident. Significant differences were observed in parameter values, particularly, those related to a long term prediction of the contamination behaviour in an urban area. This paper shows the importance of the survey for the environmental behaviour of pollutants in tropical climate conditions. (author)

  2. Spontaneous rupture of a right atrial angiosarcoma and cardiac tamponade Ruptura espontânea de angiossarcoma atrial direito e tamponamento cardíaco

    Ricardo Barros Corso; Nadja Kraychete; Sidnei Nardeli; Rilson Moitinho; Cristiano Ourives; Rosenbert Mamedio da Silva; Ricardo Eloy Pereira

    2003-01-01

    Primary cardiac angiosarcoma is a rare disease of difficult diagnosis and poor prognosis frequently associated with recurring hemopericardium. We report the case of a 30-year-old female with a right atrial angiosarcoma and spontaneous rupture to the pericardial cavity, who was diagnosed during an emergency exploratory thoracotomy, whose indication was cardiac tamponade. This is the 8th case reported in the literature. Clinical findings are discussed and a literature review is provided.O angio...

  3. Mechanical analysis of ferritic stainless steel applied in radiation tubes in high temperature; Analise mecanica de acos inoxidaveis ferriticos aplicados em tubos de radiacao em altas temperaturas

    Moreto, J.A.; Ponte, H.A.; Oliveira, V.L.; Silva, C.A. [Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil)

    2008-07-01

    Nowadays Brazilian oil refineries face an important challenge: to adjust their units to the processing of more aggressive crudes. The use of this kind of oil has caused an increase on corrosion on process streams in high temperatures. This study's objective is to evaluate the changes in mechanic properties and phases processing occurred in tubes from de radiation furnaces type A268/446 Tp ferritic stainless steel tubes used in conditions of high temperatures. For comparison samples of the APM/Kanthal alloy tube were examined. Hot tensile tests were performed in the studied materials evidence bodies. The evidence bodies for the hot tensile tests were extracted from the longitudinal position of the tubes and were machined with cylindrical shape with threads. There was a series of trials for each tube (at different traction speeds) at temperature of 600 deg C. With the traction test it was possible to evaluate resistance and ductility characteristics and was used to establish criteria for quality control to ensure satisfactory performance in certain applications. Data testing creep were performed in the evidence bodies taken from the longitudinal position of the tubes in constant charge form. Data testing creep were executed in the constant stress mode at various levels of temperature. Through data testing creep it was possible to predict for how long the material is good for use. Data from testing creep were treated by the method of Larson and Miller. (author)

  4. Temperature profile of steel bars for construction industry fabricated by the TEMPCORE process; Perfil de temperaturas em barras de aco para construcao civil fabricadas pelo processo Tempcore

    Matos Rodrigues, Paulo C. de [Fundacao Universidade Sao Joao Del Rey (FUNREI), MG (Brazil); Cetlin, Paulo R.; Paula e Silva, Adriano de; Aguiar, Maria T.P. [Minas Gerais Univ., Belo Horizonte, MG (Brazil). Escola de Engenharia

    1992-12-31

    A foreknowledge of the temperature distribution along the transverse section of steel bars produced by TEMPCORE process was made.The foreknowledge was elaborated from the study of the transverse hardness profile of the bar.That becomes relevant because the tempering temperature is the main variable of control the TEMPCORE process and therefore, it acts in the hardness of steel. Microhardness were taken along the diameter of transversal samples taken from a bar which were submitted to the TEMPCORE process and then an hardness profile was made. Other samples were also prepared in order to be submitted in water quenching followed by temper from 200 up to 920 degrees Celsius. The best equation for microhardness-tempering temperature data from steel studied is showed. The temperature profile was made from those results. (author). 6 refs., 7 figs., 4 tabs.

  5. Investigation of the benzotriazole as addictive for carbon steel phosphating; Estudo da utilizacao do benzotriazol como aditivo para a fosfatizacao de aco carbono

    Annies, V.; Cunha, M.T.; Rodrigues, P.R.P.; Banczek, E.P. [Universidade Estadual do Centro-Oeste, Guarapuava, PR (Brazil). Dept. de Quimica; Costa, I. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Terada, M. [Universidade de Sao Paulo (POLI/USP), SP (Brazil). Escola Politecnica. Dept. de Engenharia Metalurgica e de Materiais

    2010-07-01

    This work studied the viability of substitution of sodium nitrite (NaNO{sub 2}) for benzotriazole (BTAH) in the zinc phosphate bath (PZn+NaNO{sub 2}) for phosphating of carbon steel (SAE 1010). The characterization of the samples was carried out by Scanning Electron Microscopy, Optical Microscopy and X-ray diffraction. The chemical composition was evaluated by Energy Dispersive Spectroscopy. The corrosion behavior of the samples was investigated by Open Circuit Potential, Electrochemical Impedance Spectroscopy and Anodic Potentiodynamic Polarization Curves in a 0.5 mol L{sup -1} NaCl electrolyte. The experimental results showed that the phosphate layer obtained in the solution with benzotriazole (PZn+BTAH) presented better corrosion resistance properties than that obtained in sodium nitrite. The results demonstrated that the sodium nitrite NaNO{sub 2} can be replaced by benzotriazole (BTAH) in zinc phosphate baths. (author)

  6. Dissecção espontânea do tronco celíaco: qual a melhor abordagem terapêutica?

    Francisco Leonardo Galastri; Felipe Nasser; Breno Boueri Affonso; Jorge Eduardo de Amorim; Fabiellen Berzoini Travassos

    2013-01-01

    A dissecção espontânea das artérias viscerais é um evento relativamente raro. Dor abdominal súbita no epigástrio é o sintoma mais frequentemente manifestado pelos pacientes. O avanço das técnicas de exames de imagem possibilitou o diagnóstico deste evento com maior facilidade, aumentando a incidência das dissecções das artérias viscerais. O tratamento clínico conservador, a revascularização cirúrgica, e a terapia endovascular são as três possíveis opções terapêuticas. Neste artigo, relatamos ...

  7. Behaviour of steel zinc and aluminum conductors in rural electricity systems; Comportamento de condutores de aco zincado e de aluminio no sistema de eletrificacao rural (MRT)

    Silva, Simone M. da

    1989-12-31

    In the present study, electrical and mechanical properties, the price per unity of weight and the price of rural tariffs were adopted to define the behaviour of steel zinc plated conductors (1 x 3,09 mm, 3 x 2,25 mm) and aluminum conductor steel reinforced n deg o 4. With the help of the kilometer of the line and the Kw/h costs, the values of economical currents for each conductor and the power installed were obtained, varying the distance. Regression analysis were carried out to obtain the values of economically viable current and the number of transformers, in function of the distance. (author). 12 figs., 20 tabs., 35 refs

  8. Performance evaluation of cast iron pipe for crude oil and salt water transportation; Avaliacao e desempenho de duto de aco fundido no transporte de petroleo com aguas salgadas

    Silva, Carlos Alexandre Martins da [PETROBRAS Transporte S.A. (TRANSPETRO), Rio de Janeiro, RJ (Brazil); Mainier, Fernando B. [Universidade Federal Fluminense, Niteroi, RJ (Brazil)

    2005-07-01

    The present paper aims to study and to evaluate the performance of casting iron pipe for transportation of salty and produced waters, presented in the oil industry, where salt contents ranging on very large values. The cast iron above mentioned has an yield strength of 23 kg/mm{sup 2}, tensile strength of de 46 kg/mm{sup 2} (minimum) and an elongation of 15%, and contents of some chemical alloys, such as Cr (0,8 -1,3 %), Mn (1,5 % max) and Si (1,%). Nevertheless it is an exploratory study, the dynamic tests of weight loss carried out in laboratory, with specimens machined from a used pipe piece, with salty solution (3,5 % NaCl) aerated media, has shown very promising results, enabling to qualify, satisfactorily, such material for using in transportation and transferring operations of fluids with a high salty contents, such as crude oil. (author)

  9. Electro-economic, environmental and social consequences in the efficient abatement of a hydroelectric plant (C. H. Santa Rosa, CFE-ACO); Consecuencias electro-economicas, ambientales y sociales del abatimiento eficiente de una central hidroelectrica (C. H. Santa Rosa, CFE-ACO)

    Narvaez Perez, Camilo; Garcia Conejo, Dante Aristoteles [Comision Federal de Electricidad, Centro Nacional de Control de Energia, Area de Control Occidental, Zapopan, Jalisco (Mexico)]. E-mail: camilo.narvaez@cfe.gob.mx; camilo.narvaez@univa.mx; Narvaez Perez, Claudia Universidad de Guadalajara, Zapopan, Jalisco [Mexico]). E-mail: claudia_narvaez@hotmail.com; Blanco Gomez, Cesar Eduardo [Comision Federal de Electricidad, Centro Nacional de Control de Energia, Area de Control Occidental, Zapopan, Jalisco (Mexico)

    2013-03-15

    Renewable energy systems, like hydroelectric generation system gives electric energy, in reliable economic, it takes care with environment, and growths the society, if the hydroelectric dam is suitably drained in non rainy season, if we consider, flow rate in its river, rain, thunderstorms and floods, dam's size, load shape per day, generators capacity unit and the flow in turbines, generating units maintenance and other necessities like irrigation crops in farms. In this research we propose a new methodology about hydroelectric dam drained in non rainy season. But in rainy season, you can consider this methodology with few changes and you would obtain satisfactory results. The methodology is used since 2010 in the Area de Control Occidental in the Comision Federal de Electricidad with results compared with data from previous years, in which different methodologies were applied. [Spanish] Los sistemas de energias renovables, como los complejos hidroelectricos impactan de manera electrica, economica, ambiental y social, siempre y cuando se realice adecuadamente el abatimiento de la presa en el estiaje, considerando, el aporte del cauce, las lluvias aun siendo escasas, el tamano del embalse, la demanda horaria de la carga abastecida, el tamano de los generadores y su gasto turbinado, los mantenimientos de las unidades, las necesidades hidraulicas aguas abajo y demas imponderantes. En esta investigacion se propone una metodologia de abatimiento de presas de centrales hidroelectricas en estiaje. Y para tiempo de lluvias se aplica la metodologia con variantes pequenas y con resultados satisfactorios. La metodologia es utilizada desde el 2010 en el Area de Control Occidental de la Comision Federal de Electricidad, con resultados comparados con los datos de los anos anteriores, en los cuales se aplicaron metodologias diversas.

  10. The correlation between accelerated and field corrosion tests performed in carbon steel and weathering steel coupons, coated and non-coated; Correlacao entre ensaios acelerados e ensaios de campo em corpos-de-provas de aco carbono e aco patinavel, sem e com revestimento

    Antunes, Renato Altobelli

    2002-07-01

    The performance of four different organic coating systems applied to carbon and weathering steel coupons has been assessed in this investigation. applied on the surface of carbon steel and weathering steel coupons. The coupons have been evaluated using five different tests, three field tests and two accelerated tests. The field tests were carried out at three atmospheric stations, located at COSIPA in Cubatao-SP, at Alto da Serra in Cubatao-SP and at Paula Souza in Sao Paulo city. The accelerated tests consisted of (a) exposure to alternate cycles of ultraviolet radiation/condensation combined with salt spray cycles (UVCON combined with Salt Spray) and of (b) exposure to alternate cycles of ultraviolet radiation/condensation combined with the Prohesion test. The performance of the coatings was assessed by visual observation and photographs, using a method based on ASTM D-610, ASTM D-714 and ASTM-1654 standards to rank them. The oxide phases formed on the surfaces of the non-coated specimens of carbon and weathering steels, exposed to the same tests performed with the coated specimens, were identified using three different techniques: X-ray diffraction, Raman microscopy and Moessbauer spectroscopy. In the field tests, the specimens have been exposed for 1, 2, 3, 6 and 9 months. In the accelerated ones, the results were obtained after 1340 hours (4 cycles) test. The main component identified in all the specimens collected from the field tests and from the UVCON combined with the Prohesion test was lepidocrocite ({gamma}-FeOOH). Goethite ({alpha}-FeOOH ) and magnetite (Fe{sub 3}O{sub 4}) were identified as the other two main phases present in ali the specimens. In the UVCON combined with Salt Spray test, the dominant phase was magnetite, followed by goethite and lepidocrocite. The morphology of the rust formed on the specimens was examined by scanning electron microscopy (SEM). Structures corresponding to goethite and lepidocrocited were recognized on ali specimens, except those exposed to the UVCON combined with Salt Spray testo In this case, the structures corresponding to the phases magnetite and goethite were more frequently observed than that of lepidocrocite. The weathering steel specimens, in general, presented a more compact and less porous rust layer, than that of the carbon steel specimens. The atmosphere of the COSIPA station can be considered to be the most aggressive one compared to that of Alto da Serra and Paula Souza stations, because the oxide layer on its specimens was more irregular and porous than that on the specimens exposed at the other two stations. In the specimens from the Paula Souza station, the oxide layer was found to be more compact, and its atmosphere can be considered to be the least aggressive of the three locations. (author)

  11. Shared Savings Program Accountable Care Organizations PUF

    U.S. Department of Health & Human Services — SSP ACO PUF - To address the increasing number of requests for SSP ACO data, the Centers for Medicare (CM) has created a standard analytical file that CMS can use...

  12. Study of the mechanical metallic coating properties on the steel used on sucker rods; Estudo das propriedades mecanicas de revetimentos mtalicos aplicados sobre o aco utilizado em hastes de bombeio

    Santos, A.O.; Cavalcanti, E.B.; Cruz, M.C.P.; Souza, L.P. [Universidade Tiradentes, Aracaju, SE (Brazil). Inst. de Tecnologia e Pesquisa. Lab. de Energia e Materiais; Araujo, P.M.M. [Universidade Federal de Sergipe (UFS), Sao Cristovao, SE (Brazil). Nucleo de Engenharia Mecanica], e-mail: paubaumma@yahoo.com.br

    2008-07-01

    The mechanical properties of the steel carbon alloy coating with NiCr 80/20, NiCr 20/80, 95 MXC, aluminum and cupper had been studied about hardness and modulus of elasticity of coating. A time that the sucker rods will be submitted the efforts stress, is important that the applied coverings are not more rigid of what the steel carbon, because has problems of deformations in the material applied on the sucker rods. One observed that the coverings are less rigid than the steel carbon used on the sucker rods, presenting small modulus of elasticity to the ones of the sucker rods. This property is interesting for being to the sucker rods submitted the efforts stress and compression when in operation in the oil. With regard to the hardness, it was verified that the cupper and aluminum coating are less hard than the steel carbon, therefore more degradation to the consuming for abrasion. (author)

  13. Criteria and procedures for stability studies - adopted measures for improving system dynamic performance; Criterios e procedimentos para estudos de estabilidade - definicao de acoes para a melhoria do desempenho em regime transitorio e dinamico de sistemas de transmissao

    Figueiredo, Erli F. [FURNAS, Rio de Janeiro, RJ (Brazil); Fontoura, Roberto N. [ELETROBRAS, Rio de Janeiro, RJ (Brazil); Souza, Luiz Gastao C. [ELETROSUL, Curitiba, PR (Brazil); Barros, Joao Ricardo P. de [Companhia Hidroeletrica do Sao Francisco (CHESF), Recife, PE (Brazil); Aires, Joao C. de O. [Light Servicos de Eletricidade S.A., Rio de Janeiro, RJ (Brazil); Etrusco, Wellignton [Companhia Energetica de Sao Paulo (CESP), SP (Brazil); Rosa, Aciron B. de [Companhia Estadual de Energia Eletrica do Estado do Rio Grande do Sul (CEEE), Porto Alegre, RS (Brazil); Daldagan, Maria L. [Companhia Paranaense de Energia (COPEL), Curitiba, PR (Brazil); Bastos, Jose R. [Eletricidade de Sao Paulo, Sao Paulo, SP (Brazil); Yamamura, Paulo [ELETRONORTE, Belem, PA (Brazil); Luz, Ariosto [Companhia de Energia Eltrica da Bahia, Salvador, BA (Brazil); Oliveira, Elizabeth F. [CELG (Brazil); Mello, Albert C.G. de [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil); Souza, Itamar [Centrais Eletricas de Santa Catarina S.A. (CELESC), Florianopolis, SC (Brazil); Oliveira, Amaury R.C. [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil); Martins Junior, Jose A. [Companhia Paulista de Forca e Luz (CPFL), Campinas, SP (Brazil); Ferreira, Jose S. [Espirito Santo Centrias Eletricas S.A. (ESCELSA), Vitotia, ES (Brazil); Molina, Jair M. [Empresa Energetica do Mato Grosso do Sul S.A. (ENERSUL), Campo Grande, MS (Brazil); Pereira, Marcel J.A. [Centrais Eltricas do Para S.A. (CELPA)]|[Belem, PA (Brazil); Rocha Neto, Cassiano, C. [Companhia Energetica do Ceara (COELCE), Fortaleza, CE (Brazil); Coelho, Simone N. [CELPE (Brazil); Silva, Robson P. [CEAL (Brazil)

    1994-12-31

    This work presents criterion and proceedings to the analysis of the performance of AC and DC transmission systems point to point and multi-terminal, in dynamic and transient regime. (author) 9 refs., 2 figs., 2 tabs.

  14. Hardness and microstructural characterization of API 5L X70 steel pipes welded by HF/ERW process; Caracterizacao microestrutural e de dureza em tubos de aco API 5L X70 soldados pelo processo HF/ERW

    Calcada, Mauricio Vieira; Voorwald, Herman Jacobus Cornelis; Nascimento, Marcelino Pereira do [UNESP, Guaratingueta, SP (Brazil). Faculdade de Engenharia

    2010-07-01

    The materials that stand in the manufacture of steel pipes are called API, that should have, high mechanical resistance, high corrosion resistance, high fatigue resistance, good weldability, and other properties. Thus, the purpose of this project was to evaluate the microstructure and hardness of welded joints by the HF/ERW process of API 5L X70 steel pipes. The microstructural analysis was performed using a surface finish with grit sizes from 220 to 25 {mu}m e polishing with diamond paste from 9 {mu}m to 0.05 {mu}m; the revelation was made with 3% Nital attack. The Vickers hardness was performed across the welded joint by 33 points to indentation. The results were: 80.5 {+-} 3.4% of ferrite and 19.5 {+-} 3.4% of perlite for microanalysis. As for hardness, the values were: 215.69 HV10 for weld line, 218.65 HV10 for ZTA and 218.95 HV10 for base metal. (author)

  15. "Non Working Beating Heart": novo método de proteção miocárdica no transplante cardíaco Non Working Beating Heart: a new strategy of myocardial protection during heart transplant

    Jarbas Jakson Dinkhuysen

    2011-12-01

    Full Text Available INTRODUÇÃO E OBJETIVO: Trata-se do implante em posição ortotópica bicaval bipulmonar do coração doado batendo em normotermia. Este estudo busca diminuir o tempo isquêmico e criar condições de ir se adaptando ao organismo hospedeiro. MÉTODOS: Já em CEC, a primeira anastomose a ser feita é a da aorta, reperfundindo as artérias coronárias e recuperando os batimentos. As restantes são realizadas com o coração batendo em ritmo sinusal, sendo a da artéria pulmonar a última. Esta metodologia foi aplicada em 10 pacientes receptores, sendo oito do sexo masculino, com idades entre 16 e 69 (média de 32,7 anos, PSAo 90-100 (média de 96 mmHg, PSAP 25-65 (média de 46,1 mmHg, RVP 0,9-5,0 (média de 3,17 Wood, GTP 4-13 (média de 7,9 mmHg. Entre os 10 doadores, sete eram do sexo masculino, com idade entre 15 e 48 (média 27,7 anos, peso entre 65 e 114 kg (média de 83,1 kg. As causas do coma encefálico foram: TCE (cinco, AVCH (quarto e tumor cerebral (um. RESULTADOS: O tempo isquêmico variou de 58 a 90 minutos (média 67,6 minutos, sendo que oito doadores estavam em hospitais da região metropolitana de São Paulo e dois em cidades distantes. Todos os enxertos, após completadas as anastomoses, retomaram o fluxo e o débito, mantendo bons parâmetros, com baixa dosagem de inotrópico e mantiveram estas condições no pós-operatório imediato. Não ocorreram óbitos e todos os pacientes obtiveram alta hospitalar. A evolução tardia variou de 20 dias a 10 meses, tendo ocorrido um óbito ao 4º mês pós-transplante, por sepse. CONCLUSÕES: Esta metodologia, além de reduzir o tempo isquêmico, permite ao órgão doado recuperar e manter seus batimentos sem pré nem pós-carga durante o implante, o que enseja proporcionar recuperação fisiológica, ultraestrutural, imunológica, inflamatória e mecânica do enxerto, com resultados consistentes precoces e tardios.BACKGROUND AND OBJECTIVE: We attempt to reduce the ischemic time during implantation of the donor heart in the bicaval bipulmonary orthotopic position using normothermic beating heart and thus, facilitate the transplanted heart adaptation to the recipient. This study presents a small experience about a new strategy of myocardial protection during heart transplant. METHODS: In cardiopulmonary bypass, the aorta anastomosis was done first, allowing the coronary arteries to receive blood flow and the recovering of the beats. The rest of the anastomosis is performed on a beating heart in sinus rhythm. The pulmonary anastomosis is the last to be done. This methodology was applied in 10 subjects: eight males, age 16-69 (mean 32.7 years, SPAo 90-100 mmHg (mean 96 mmHg, SPAP 25-65 mmHg (mean 46.1 mmHg, PVR 0.9 to 5.0 Wood (mean 3.17 Wood, GTP 4-13 mmHg (mean 7.9 mmHg, and eight male donors, age 15-48 years (mean 27.7 years, weight 65-114 kg (mean 83.1 kg. Causes of brain coma: encephalic trauma in five hemorrhagic stroke in four, and brain tumor in one. RESULTS: The ischemic time ranged from 58-90 minutes (mean 67.6 minutes and 8 donors were in hospitals of Sao Paulo and two in distant cities. All grafts assumed the cardiac output requiring low-dose inotropic therapy and maintained these conditions in the postoperative period. There were no deaths and all were discharged. The late evolution goes from 20 days to 10 months with one death occurred after 4 months due to sepsis. CONCLUSION: This method, besides reducing the ischemic time of the procedure, allows the donated organ to regain and maintain their beats without pre or after load during implantation entailing the physiological recovery of the graft.

  16. Infarto cerebral hemorrágico por embolización de un trombo mural cardíaco Hemorrhagic cerebral infarction due to embolization of a mural thrombus within the right ventricle

    Marín, R; Rico, A.; Blanco, M.; E. Barrero; I. Manresa; Santos, M.; J. Lucena

    2008-01-01

    Las enfermedades cerebrovasculares son consecuencia de una alteración en la circulación cerebral. Su forma más distintiva de presentación es el ictus, entendido como un déficit neurológico focal de instauración brusca y evolución rápida. Un infarto cerebral de origen oclusivo puede deberse bien a una trombosis in situ o bien a una embolia procedente de un foco distante. En las embolias cerebrales la causa principal son los trombos murales cardiacos y el área encefálica afectada con mayor frec...

  17. Organogênese e transformação genética de maracujá amarelo (Passiflora edulis f. flavicarpa Deg.) com os genes CMe-ACO1 AS e nptll via Agrobacterium tumefaciens

    Winkler, Larissa Macedo

    2013-01-01

    O Brasil é o principal produtor mundial de maracujá-amarelo (Passiflora edulis f. flavicarpa Deg.). Seus frutos, de grande valor nutricional e farmacêutico são comercializados in natura e industrializados, garantindo o abastecimento do mercado interno e exportação. Contudo, seus frutos perdem grande quantidade de água durante o processo de maturação, conferindo à eles um aspecto de murcha em poucos dias, além de aumentar a fragilidade durante o transporte. Assim, o presente trabalho teve como...

  18. Structural steels for fixed offshore platforms: technical challenges at the Brazilian national supply chain; Acos estruturais para plataformas fixas offshore: desafios tecnicos junto a cadeia de suprimentos nacional brasileira

    Castro, Fabio Modesti Orsini de [Promon Engenharia Ltda., Rio de Janeiro, RJ (Brazil)

    2012-07-01

    This paper presents the main technical requirements for structural steel applied to the construction of bottom fixed offshore platforms, based on the most widely adopted and recognized actual standards. The mechanical properties and lab tests necessary to fulfill the Risk Management and E and P companies requirements are presented aiming to build the theoretical bases necessary for the engineering design of projects of this kind. The main types of steel available in the national market are presented at the end, giving an overall look at the Brazilian steel supply chain. (author)

  19. Evaluation of the potential of additives as corrosion inhibitors of CA-50 carbon steel used as reinforcement in concretes; Avaliacao da potencialidade de aditivos como inibidores de corrosao do aco carbono CA-50 usado como armadura de estruturas de concreto

    Mennucci, Marina Martins

    2006-07-01

    In this work, various compounds were tested to evaluate their potential capability for their use as corrosion inhibitors of carbon steel reinforcement in concretes. The additives tested were sodium benzoate, polyethylene glycol, hexamethylenetetramine, benzotriazole and yttrium carbonate. Initially, exploratory tests were carried out to select the ones to be used as corrosion inhibitors, based on the inhibit ion efficiency determined from electrochemical tests, specifically polarization tests and electrochemical impedance spectroscopy. These tests were carried out in a solution composed of 0.01 N sodium hydroxide (NaOH) and 0.05 N potassium hydroxide (KOH) to simulate the composition of the solution inside the pores in concretes. The additive that presented the most promising potential to be used as corrosion inhibitor was benzotriazole (BTA). After the elimination of some compounds and selection of the additive with higher corrosion inhibit ion efficiency in the test medium, the effect of its concentration on the corrosion inhibition efficiency was evaluated. Sodium nitrite solutions with the same concentrations as those solutions with BTA were tested for comparison reasons. Sodium nitrite is a well established corrosion inhibitor for carbon steel reinforcement in concretes but it has been related to toxic effects. The BTA was associated to higher corrosion inhibition efficiencies than that of sodium nitrite in similar concentrations. A blackish adherent film was formed on the steel surface exposed to BTA solutions during long periods of immersion in the alkaline medium. The results suggest that BTA is a potential candidate for substitution of nitrites as corrosion inhibitor of reinforcements in concrete. (author)

  20. Behaviour of steel pipe exposed to fouling by heavy oil during core-annular flow; Comportamento de tubo de aco exposto a sujeira de oleo pesado durante escoamento nucleo-anular

    Barbosa, Adriana; Bannwart, Antonio C. [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Engenharia de Petroleo

    2004-07-01

    The use of water-assisted technologies such as core-annular flow to the pipelines of viscous oils has been proposed as an attractive alternative for production and transportation of heavy crudes in both onshore and offshore scenarios. Usually, core-annular flow can be created by injecting a relatively small water flow rate laterally in the pipe, so as to form a thin water annulus surrounding the viscous oil, which is pumped through the center. The reduction in friction losses obtained thanks to lubrication by water is significant, since the pressure drop in a steady state core flow becomes comparable to water flow only. For a complete assessment of core flow technology, however, unwanted effects associated with possible oil adhesion onto the pipe wall should be investigated, since these may cause severe fouling of the wall and pressure drop increase. It has been observed that oil adhesion on metallic surfaces may occur for certain types of crude and oilphilic pipe materials. In this work we present results of pressure drop monitoring during 35 hour-operation of a heavy oil-water core annular flow in a 26.08 mm. i.d. horizontal steel pipe. The oil used is described in terms of its main components and the results of static wet ability tests are also presented for comparison (author)

  1. Participação dos canais de sódio voltagem-dependentes no efeito tipo antimaníaco da feinitoína e da carbamazepina na hiperlocomoção induzida por metilfenidato

    Tonelli, Denise Aparecida Gianoti

    2013-01-01

    Resumo Alguns anticonvulsivantes como o valproato e a carbamazepina são efetivos no tratamento da fase maníaca do transtorno afetivo bipolar e embora possuam algumas diferenças farmacológicas, todos compartilham de um efeito comum que é o bloqueio dos canais de sódio voltagem-dependentes. A fenitoína também promove tal efeito e recentemente foi demonstrado que ela reduziu o tempo de imobilidade dos camundongos submetidos ao teste de natação forçada, efeito este que é bloqueado pela veratrina,...

  2. Study of API 5L X70 steel corrosion processes when in contact with some Brazilian soils; Estudo dos processos de corrosao de acos API 5L X70 em contato com alguns dos solos do Brasil

    Jesus, Sergio Luis de

    2007-07-01

    Pipelines, fuel storage tanks and other metallic structures are in permanent contact and exposed to different types of soils, of horizons or layers, or of soil aggressiveness. This interaction may cause expressive damages to the environment and to the planned work. Contamination may occur due to leakage of stored products, splitting during transportation, accidents caused by pipelines without extensive maintenance. The result of these accidents could be, among others, some financial losses. In order to recognize the dynamic interactions between metallic surfaces and the environment it is crucial to have preventive actions and to develop better-applied materials. API steel 5L X70 has been used in structures of low and high pressure with high mechanical strength and corrosion and, even so, it is susceptible to etching corrosion since it is in contact with different environments from mangrove regions to industrial environments. The present case evaluated the role of 5L X70 API steel in contact with different soil horizons representative of the Brazilian soil. This investigation correlated chemical species with solute ions in soil solution, secondary and primary phase minerals besides physical and chemical characteristics as pH, electric conductivity, total dissolved solids, among others, to the results of corrosion resistance and ways of corrosion. The evaluation was carried out using x-ray diffractometry, scanning electron microscopy, total reflection x-ray fluorescence, fuel injection flow besides texture and gravimetric analyses to soil characterization and mineralogy, identification of corrosion products, soil solution analyses, evaluation of tested materials and classification of ways and types of corrosion. This was an attempt to integrate the data to a better understanding of the process involving reagents and products. The results showed that different soil horizons such as different types of analyzed soils produce specific etching in metallic structures showing this selectivity. The study also shows that these results can be readily obtained with soil solution as an analytical means in comparison with nowadays evaluations. (author)

  3. One safety critical indicators model for regulatory actions on nuclear power plants based on a level 1 PSA; Um modelo de indicadores criticos de seguranca para acoes regulatorias em usinas nucleares baseado em uma APS nivel 1

    Araujo, Jefferson Borges

    2006-03-15

    This study presents a general methodology to the establishment, selection and use of safety indicators for a two loop PWR plant, as Angra 1. The study performed identifies areas considered critical for the plant operational safety. For each of these areas, strategic sub-areas are defined. For each strategic sub-area, specific safety indicators are defined. These proposed Safety Indicators are based on the contribution to risk considering a quantitative risk analysis. For each safety indicator, a goal, a bounded interval and proper bases are developed, to allow for a clear and comprehensive individual behavior evaluation. Additionally, an integrated evaluation of the indicators, using expert systems, was done to obtain an overview of the plant general safety. This methodology can be used for identifying situations where the plant safety is challenged, by giving a general overview of the plant operational condition. Additionally, this study can also identify eventual room for improvements by generating suggestions and recommendations, as a complement for regulatory actions and inspections, focusing resources on eventual existing weaknesses, in order to increase or maintain a high pattern of operational safety. (author)

  4. Efectos de los hidrocoloides en las características fisicoquímicas y reológicas de pastas libres de gluten aptas para individuos celíacos

    Larrosa, Virginia Judit

    2014-01-01

    El propósito de esta Tesis fue el diseño de pastas libres de gluten (LG), aptas para individuos que padecen la enfermedad celiaca, así como en los métodos de preservación industriales a fin de obtener un producto de óptimas características, de manera tal que se pueda producir y comercializar manteniendo sus atributos de calidad. En una primera etapa se adoptó una formulación básica compuesta por mezcla de almidón y harina de maíz, aceite de girasol, mezclas huevo y clara en polvo, mezcla de ...

  5. Steel production by continuous casting on Companhia Siderurgica Nacional (CSN), Volta Redonda, RJ, Brazil; Producao de aco via lingotamento continuo na Companhia Siderurgica Nacional (CSN), Volta Redonda, RJ, Brazil

    Azevedo, Renato D. de; Souza Macedo, Humberto de; Alencar Figueira Quaresma, Jose de; Bittencourt, Laercio S.; Coutinho Neto, Lourival [Companhia Siderurgica Nacional, Volta Redonda, RJ (Brazil)

    1984-12-31

    The reasons that lead Brazilian National Steel Co. to expand its continuous casting plant are presented. Start up of the new equipment, training and operating crews, production growth and operational practices evolution, are discussed. Development of steel specifications for continuous casting, replacing the conventional ingot production, the evolution of its quality and production at the LD steel casting are commented. Its production possibilities under new specifications and the development of hot slab charging process its also shown. 12 figs., 3 tabs.

  6. Machining tools in AISI M2 high-speed steel obtained by spray forming process; Ferramentas de usinagem em aco rapido AISI M2 obtido por conformacao por 'spray'

    Jesus, Edilson Rosa Barbosa de. E-mail: erbjesus@usp.br

    2004-07-01

    The aim of the present work was the obtention of AISI M2 high-speed steel by spray forming technique and the material evaluation when used as machining tool. The obtained material was hot rolled at 50% and 72% reduction ratios, and from which it was manufactured inserts for machining tests. The performance of inserts made of the spray formed material was compared to inserts obtained from conventional and powder metallurgy (MP) processed materials. The spray formed material was chemical, physical, mechanical and microstructural characterised. For further characterisation, the materials were submitted to machining tests for performance evaluation under real work condition. The results of material characterisation highlight the potential of the spray forming technique, in the obtention of materials with good characteristics and properties. Under the current processing, hot rolling and heat treatments condition, the analysis of the results of the machining tests revealed a very similar behaviour among the tested materials. Proceeding a criterious analysis of the machining results tests, it was verified that the performance presented by the powder metallurgy material (MP) was slight superior, followed by conventional obtained material (MConv), which presented a insignificant advantage over the spray formed and hot rolled (72% reduction ratio) material. The worst result was encountered for the spray forming and hot rolled (50% reduction ratio) material that presented the highest wear values. (author)

  7. Comparative study of AISI M3:2 high speed steel produced through different techniques of manufacturing; Estudo comparativo de acos rapidos AISI M3:2 produzidos por diferentes processos de fabricacao

    Araujo Filho, Oscar Olimpio de

    2006-07-01

    In this work AISI M3:2 high speed steels obtained through different techniques of manufacturing, submitted to the same heat treatment procedure were evaluated by measuring their mechanical properties of transverse rupture strength and hardness. Sinter 23 obtained by hot isostatic pressing (HIP), VWM3C obtained by the conventional route and a M3:2 high speed steel obtained by cold compaction of water atomized powders and vacuum sintered with and without the addition of a small quantity of carbon were evaluated after the same heat treatment procedure. The vacuum sintered M3:2 high speed steel can be an alternative to the more expensive high speed steel produced by hot isostatic pressing and with similar properties presented by the conventional one. The characterization of the vacuum sintered M3:2 high speed steel was performed by measuring the densities of the green compacts and after the sintering cycle. The sintering produced an acceptable microstructure and densities near to the theoretical. The transverse rupture strength was evaluated by means of three point bending tests and the hardness by means of Rockwell C and Vickers tests. The technique of scanning electronic microscopy (SEM) was used to evaluate the microstructure and to establish a relation with the property of transverse rupture strength. The structure was determined by means of X-ray diffraction (XRD) patterns and the retained austenite was detected to all the conditions of heat treatment. The main contribution of this work is to establish a relation between the microstructure and the mechanical property of transverse rupture strength and to evaluate the AISI M3:2 vacuum sintered high speed steel as an alternative to the similar commercial high speed steels. (author)

  8. Application of Nonlinear Simplex ACO in Waste Transport%非线性单纯形蚁群算法在垃圾运输问题中的应用

    李舟; 向长城

    2011-01-01

    Municipal solid waste transport management is an important issue.To address the problem, a mathematical model for waste transport is first established to get the objective function and constraints.According to the mathematical model for waste transport,an improved ant colony algorithm is used for computing.The non-linear simplex algorithm is used to generate the initial ant,and then optimize it with ant colony algorithm.Finally,the algorithm is applied to municipal waste transportation model,and good results were achieved.%城市垃圾运输问题是困扰一个城市管理的重要课题.针对该问题,首先建立了垃圾运输问题的数学模型,建立目标函数和约束条件.针对垃圾运输问题数学模型,采用改进的蚁群算法进行计算,利用非线性单纯形算法生成初始蚂蚁,然后结合蚁群算法进行优化.将该算法最后应用到城市垃圾运输模型,取得了较好的效果.

  9. Microstructural characterization of IF steel after severe plastic deformation via ARB and subsequent heat treatment; Caracterizacao microestrutural de um aco IF apos deformacao plastica severa via ARB e posterior recozimento

    Oliveira, F.C.; Abrantes, A.L.A.; Lins, J.F.C., E-mail: cristinafo2@hotmail.co [Universidade Federal Fluminense (PPGEM/UFF), Volta Redonda, RJ (Brazil). Programa de Pos-graduacao em Engenharia Metalurgica

    2010-07-01

    This study aimed to evaluate the microstructural evolution of a titanium stabilized IF steel deformed to warm through the ARB process for 5 consecutive cycles and then annealing at 600 deg C for 1 h. The material was characterized with the aid of the techniques of scanning electron microscopy and electron backscatter diffraction (Electron Backscatter Diffraction - EBSD). An intense process of microstructural refinement was observed in the deformed material and the phenomenon of dynamic recovery was predominant. It can be concluded that the annealing of severely deformed material was not sufficient for a complete recrystallization of the microstructure. (author)

  10. An ACO-Based Fair Energy Usage Routing Algorithm for Wireless Sensor Networks%基于蚁群优化的无线传感器网络能量均衡路由算法

    梁华为; 陈万明; 李帅; 梅涛; 孟庆虎

    2007-01-01

    如何有效使用无线传感器节点有限的能量来最大化网络的寿命是无线传感器网络研究的重要问题.网络能量是否均衡消耗对网络寿命有着决定性的影响.本文将蚁群优化算法应用于无线传感器网络的路径选择,提出一种基于蚁群优化的无线传感器网络能量均衡路由算法.该算法利用蚁群的动态适应性和寻优能力在网络最短路径和能量均衡消耗之间进行平衡,以达到网络能量的优化均衡消耗,进而延长整个网络的寿命.仿真实验表明,该算法在延长网络寿命方面效果较显著,与最短路径路由算法相比网络寿命延长超过33%.

  11. Effect of annealing temperature on microstructure of ferritic stainless steels with high Mo content; Efeito da temperatura de recozimento na microestrutura em acos inoxidaveis ferriticos com alto teor de Mo

    Abreu, H.F.G.; Miranda, H.C. [Universidade Federal do Ceara (UFC), Fortaleza (Brazil). Dept. de Engenharia Metalurgica e de Materiais; Herculano, L.F.G. [Universidade Federal do Ceara (UFC), Fortaleza (Brazil). Lab. de Caracterizacao de Materiais; Tavares, S.S.M. [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Dept. de Engenharia Mecanica

    2006-07-01

    The petroleum refined in Brazilian refining plants is characterized by its high content of sulphur. This fact has increased problems related to naphtenic corrosion. It is known by the experience in refining that steels with high contents of Mo present good naphtenic corrosion resistance. This papers studied aspects referring to mechanical properties and microstructure of high Mo ferritic stainless steels developed in laboratory as a function of annealing temperature. Results showed that temperatures between 1000 and 1050 deg C were more suitable to the steels studied. (author)

  12. Alpha prime effect on mechanical properties and corrosion resistance of UR 52N+ duplex stainless steel; Efeito da fase alfa linha nas propriedadesmecanicas e de resistencia a corrosao do aco inoxidavel duplex UR 52N+

    Fontes, Talita Filier

    2009-07-01

    Alpha prime phase leads to decreased corrosion resistance and mechanical properties losses of duplex stainless steels. In this work mechanical and electrochemical tests were performed in duplex stainless steel UR 52N+ aged at 475 degree C for various periods in order to determine the sensibility of these tests to alpha prime presence. Hardness tests showed a gradual increase in its values; on the other hand, impact tests revealed that the material aged for 12h losses about 80% of energy absorption capacity of the solution annealed sample. Notwithstanding cyclic polarization tests showed that significant changes are only noted for aging times greater than 96h. (author)

  13. Characterization by X ray diffraction of deleterious phases precipitated in a super duplex stainless steel; Caracterizacao por difracao de raios X de fases deleterias precipitadas em aco inoxidavel superduplex

    Pardal, Juan M.; Tavares, Sergio S. Maior; Fonseca, Maria P. Cindra; Montenegro, Talles Ribeiro, E-mail: juanpardal@vm.uff.b [Universidade Federal Fluminense (PGEMEC/UFF), Niteroi, RJ (Brazil). Programa de Pos-graduacao em Engenharia Mecanica; Dias, Antonio Jose N.; Almeida, Sergio L. de [Instituto Nacional de Tecnologia (INT), Rio de Janeiro, RJ (Brazil). Div. de Materiais Ceramicos e Metalicos. Lab. de Tecnologia de Materiais

    2010-07-01

    In this work the identification and quantification of deleterious phases in two super duplex stainless steels grade UNS S32750, with quite different grain sizes, was performed by X-ray diffraction. The materials were isothermally aged in the 800 . 950 deg C range. Direct comparison method was used to quantify the ferrite phase in each sample. The amount of deleterious phases ({sigma}, {chi} and {gamma}2) formed was calculated by the difference of the amount of ferrite phase measured in each specimen to the amount of ferrite initially measured in the un-aged steel. The results obtained give an useful contribution to the understanding of kinetics of deleterious phases precipitation in super duplex steels. (author)

  14. Effect of sigma phase in the repassivation potential of austenitic-ferritic stainless steel SEW 410 Nr. 14517; Efeito da fase sigma no potencial de repassivacao do aco inoxidavel austeno-ferritico SEW 410 Nr. 14517

    Itman Filho, A.; Pimenta, C.C.; Santos, C.M.L. [Instituto Federal do Espirito Santo, Vitoria (Brazil)], e-mail: andrei@ifes.edu.br; Casteletti, L.C. [Escola de Engenharia de Sao Carlos - EESC/USP, SP (Brazil)

    2010-07-01

    The austenitic-ferritic stainless steels, due to the optimum compromise between mechanical properties and corrosion resistance, are being used in many applications, as chemical and oil industries. In the oil exploitation, the effect of erosion-corrosion in acid environment is responsible for the increment in the equipment maintenance costs. Regarding the interest in researches of deep water oil exploitation, the proposal of this study was to evaluate the effect of the heat treatment at 850 degree C of the austenitic-ferritic stainless steel SEW 410 Nr.14517. Microstructural characterizations, microhardness measurements of the phases and corrosion tests were accomplished to evaluate the samples. The pitting potential values were obtained by galvanostatic tests in H{sub 2}SO{sub 4} acid solution. The results showed that the volumetric percentages of sigma phase increased while the ferritic phase percentages decreased, when the heat treatment time increased. The sigma phase promoted hardness increase with little corrosion resistance decrease in the austenitic-ferritic stainless steel, too. (author)

  15. The actions to incentive the use of thermal-solar systems in brazilian residences of social interest; As acoes para o incentivo ao uso de sistemas termossolares na habitacao brasileira de interesse social

    Fantinelli, Jane Tassinari [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Planejamento de Sistemas Energeticos]. E-mail: janetassinari@terra.com.br; Pereira, Jose Tomaz Vieira [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Faculdade de Engenharia Mecanica]. E-mail: tomaz@unicamp.br; Pereira, Elizabeth Marques Duarte [Pontificia Univ. Catolica de Minas Gerais (PUC-MG), Belo Horizonte (Brazil). Coordenadora do Centro Brasileiro de Desenvolvimento da Energia Solar e Termica (GREEN Solar)]. E-mail: elizabeth.pereira@green.pucminas.br

    2006-07-01

    This work presents an inquiry of the actions and promotions developed for the public power, since the first program of considered solar energy in 1987, Pro-Solar, and the successive plans and action that excessively the agents had developed for the stimulation to the substitution of the electric shower of water heating for solar collectors among classes of low-cost houses brazilian. The carried through boarding was historical, so that the period of training could be verified that if finds the public plans for the adoption of mechanisms that come to stimulate the diffusion of the solar technology in the housing of social interest. (author)

  16. Prevalência de estenose das artérias renais em 1.656 pacientes que realizaram cateterismo cardíaco Prevalence of renal artery stenosis in 1,656 patients who have undergone cardiac catheterization

    Rogério Tadeu Tumelero

    2006-09-01

    Full Text Available OBJETIVO: Determinar a prevalência de estenose da artéria renal (EAR em pacientes submetidos a cineangiocoronariografia. MÉTODOS: Estudo prospectivo, considerando 1.656 cinean-giocoronariografias seguidas de aortografia, entre janeiro/2002 e fevereiro/2004, de pacientes encaminhados à cineangiocoronariografia diagnóstica com história ou não de hipertensão arterial sistêmica (HAS. RESULTADOS: Dos 1.656 pacientes, a idade média foi de 61,6 ± 11,8 anos, 53,8% eram do sexo masculino, 10,2% eram diabéticos, 63,8% apresentavam coronariopatia obstrutiva. A presença de EAR maior que 50% foi observada em 228 (13,8% pacientes, e em 25 (1,5% destes, ocorreu bilateralmente. A coronariopatia obstrutiva foi definida como estenose que causa redução do lúmen do vaso em 50% ou mais, em um, dois ou três vasos principais, denominados uniarterial, biarterial ou triarterial, respectivamente.A quantificação era realizada através da análise visual da angiografia. Comparando os grupos com e sem EAR > 50%, observou-se diferença estatisticamente significativa quanto a gênero, idade, ocorrência de diabete melito, PA e função ventricular esquerda. Não houve diferença significativa, no entanto, quanto à ocorrência de obstrução coronariana > 50%. Quando, porém, a EAR considerada é > 70%, observa-se diferença significativa quanto a PA, associação à obstrução coronariana > 50% e à disfunção ventricular esquerda, maiores no grupo com EAR. CONCLUSÃO: A prevalência de EAR neste estudo foi comparável àquela das grandes casuísticas da literatura e, em razão de sua importância pela associação com HAS e doença renal terminal (DRT e suas seqüelas, devemos estar atentos para seu diagnóstico angiográfico.OBJECTIVE: To determine the prevalence of renal artery stenosis (RAS in patients who have undergone cineangiocoronariography. METHODS: Prospective study of cineangiocoronariography and aortography examinations conducted between January 2002 and February 2004 on 1,656 hypertensive and normotensive patients who underwent the examinations to confirm the diagnosis of obstructive coronary artery disease or valve disease. RESULTS: The average age of the 1,656 patients was 61.6 ± 11.8 years. Eight hundred and ninety-one (53.8% were male, 169 (10.2% were diabetic and 1,054 (63.8% presented obstructive coronary artery disease. Renal stenosis greater than 50% was observed in 228 (13.8% patients, and 25 (1.5% had bilateral stenosis. Obstructive coronary artery disease was defined as stenosis greater than or equal to 50% of the vessel lumen, in one, two or three main arteries, classified as single, double or triple vessels, respectively. Quantification was conducted using visual analysis of the angiography. Comparison of the groups with and without renal artery obstruction > 50%, revealed significant statistical differences in relation to gender, age, diabetes mellitus, blood pressure and left ventricular function. However, no statistical difference was noted in relation to the occurrence of coronary artery obstructions > 50%. Nevertheless, renal artery obstructions > 70%, revealed significant differences in relation to blood pressure, coronary artery obstructions > 50% and left ventricular function, which were all higher in the renal artery obstruction group. CONCLUSION: The prevalence of RAS found in our study was comparable to that reported by major medical literature case studies. RAS is associated with systemic hypertension (SH, end-stage renal disease (ESRD and its sequelae, emphasizing how important it is that we are aware of possible candidates for angiographic diagnosis of this disease.

  17. Los segmentos cardíacos primitivos, su implicación en la cardiogénesis normal aplicada a la cardiología pediátrica

    Salazar García, Marcela; Sánchez Gómez,Concepción; Contreras Ramos,Alejandra; Carrillo Ávalos,Blanca A; Revilla Monsalve,Ma Cristina; Palomino Garibay,Miguel Ángel

    2006-01-01

    El gran desarrollo de la imagenología diagnóstica en la cardiología pediátrica ha exigido un conocimiento preciso de la anatomía alterada de los corazones con cardiopatía congénita. De esta manera, la información sobre la embriología cardíaca, en los aspectos morfológicos y moleculares constituye un fundamento para comprender la anatomía de los corazones mal formados. Con base en estos hechos, en este trabajo se revisa la cardiogénesis normal, integrando los nuevos hallazgos logrados experime...

  18. A Grid Task Scheduling Method Based on Min-Min and ACO Algorithm%基于Min-Min和蚁群算法的网格任务调度方法

    黄学雨; 何焕; 戴志晃

    2009-01-01

    网格任务调度是网格计算的研究热点,也是一个NP难问题.文章结合Min-Min算法和蚁群算法的优点,提出了一种基于Min-Min蚁群算法(MMACO)的任务调度方法.仿真实验表明:在网格环境下,该算法具有较好的全局最优求解能力和较快的收敛速度.

  19. Effect of shot peening treatment in the behavior of residual stress in duplex stainless steel during medium cycle fatigue; Efeito do tratamento de shot peening no comportamento das tensoes residuais em aco inoxidavel duplex durante fadiga de medio ciclo

    Pedrosa, Peter D.S.; Rebello, Joao Marcos A. [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEMM/COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Programa de Engenharia Metalurgica e de Materiais; Fonseca, Maria P. Cindra, E-mail: mcindra@vm.uff.b [Universidade Federal Fluminense (PGMEC/UFF), Niteroi, RJ (Brazil). Escola de Engenharia. Programa de Pos-Graduacao em Engenharia Mecanica

    2010-07-01

    The lifetime of duplex stainless steel parts experiencing cyclic fatigue is directly influenced by the residual stresses present in the ferrite and austenite phases. The motivation for this work was to analyze the behaviour of the residual stresses fields introduced by shot peening treatment in both phases, in the sample surface as in the subsurface layers, in low fatigue cycles, using the X-rays diffraction technique. The results shows that the compressive residual stresses introduced by the shot peening treatment in both phases improved fatigue life of the material. However, the cyclical loads produce partial or total relief in these residual stresses fields. It was verified that the shot peening process induced the formation of microcracks only in the ferrite phase. The largest variations in the total compressive residual stresses fields also occurred in this phase. The samples surfaces were analyzed by scanning electron microscopy. (author)

  20. The role of iliopsoas muscle in the development of degenerative disease of the hip (Arthrosis) = El papel del músculo psoas-ilíaco en el desarrollo de la coxartrosis

    Suvorova Suvorova, Yulia

    2016-01-01

    A medida que la generación del baby boom alcanza a una edad de 60 años y más, habrá una gran demanda sobre los servicios de cirujanos ortopédicos para las intervenciones quirúrgicas de reemplazo de cadera . Esto podría llevar un aumento en las listas de espera para este procedimiento y que a su vez conduce al dolor, la disfunción y la posible discapacidad en este grupo de personas. Hay una posibilidad fuerte y se demostrará en esta tesis de que por intervención no quirúrgica temprana diri...

  1. Mechanical properties of API X80 steel pipe joints welded by Flux Core Arc Weld Process; Propriedades mecanicas de juntas de tubos de aco API X80 soldadas com arame tubulares

    Ordonez, Robert E. Cooper; Silva, Jose Hilton F.; Trevisan, Roseana E. [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Engenharia de Fabricacao

    2003-07-01

    Flux Core Arc Welding processes (FCAW) are beginning to be applied in pipeline welds, however, very limited experimental data regarding mechanical properties of pipeline weld joints with these processes are available in the literature. In this paper, the effects of preheat temperature and type of FCAW on mechanical properties (microhardness and tensile strength) of API X80 weld joint steel are presented. FCAW processes with gas protection and self-shielded were used. Multipasses welding were applied in 30'' diameter and 0,625'' thickness tubes. Influence factors were: FCAW type and preheat temperature. Acceptance criteria of welded joints were evaluated by API 1104 standard for tensile strength test and ASTM E384-99 for microhardness test. The results obtained showed that FCAW type and preheat temperature have no influence on mechanical properties of API X80 joint steel. (author)

  2. Aluminum and steel adhesion with polyurethanes from castor oil adhesives submitted to gamma irradiation;Estudo da adesividade do aco e aluminio com adesivo de poliuretana derivada de oleo de mamona submetido a radiacao gama

    Azevedo, Elaine C.; Assumpcao, Roberto L.; Nascimento, Eduardo M. do, E-mail: elainazeve@utfpr.edu.b [Universidade Tecnologia Federal do Parana (UTFPR), Curitiba, PR (Brazil); Claro Neto, Salvador [Universidade de Sao Paulo (USP), Sao Carlos, SP (Brazil); Soboll, Daniel S. [Universidade Tecnologia Federal do Parana (CPGEI/UTFPR), Curitiba, PR (Brazil). Programa de Pos-Graduacao em Engenharia Eletrica e Informatica Industrial; Lepienski, Carlos M., E-mail: elainazeve@utfpr.edu.b [Universidade Tecnologia Federal do Parana (UTFPR), Curitiba, PR (Brazil)

    2009-07-01

    Polyurethanes adhesive from castor oil is used to join aluminum and steel pieces. The effect of gamma radiation on the resistance to tension tests is investigated. The aluminum and steel pieces after being glued with the adhesive were submitted to gamma irradiation in doses of 1 kGy, 25 kGy and 100 kGy. The rupture strength of the joints after irradiation have a slightly increase or remains practically unchanged indicating that the adhesive properties is not affected by the gamma radiation. (author)

  3. Study of corrosion resistance of AISI 444 ferritic stainless steel for application as a biomaterial; Estudo da resistencia a corrosao do aco inoxidavel ferritico AISI 444 para aplicacao como biomaterial

    Marques, Rogerio Albuquerque

    2014-09-01

    Ferritic stainless steels are ferromagnetic materials. This property does not allow their use in orthopedic prosthesis. Nevertheless, in some specific applications, this characteristic is very useful, such as, for fixing dental and facial prostheses by using magnetic attachments. In this study, the corrosion resistance and cytotoxicity of the AISI 444 ferritic stainless steel, with low nickel content, extra-low interstitial levels (C and N) and Ti and Nb stabilizers, were investigated for magnetic dental attachments application. The ISO 5832-1 (ASTM F-139) austenitic stainless steel and a commercial universal keeper for dental attachment (Neo-magnet System) were evaluated for comparison reasons. The first stainless steel is the most used metallic material for prostheses, and the second one, is a ferromagnetic keeper for dental prostheses (NeoM). In vitro cytotoxicity analysis was performed by the red neutral incorporation method. The results showed that the AISI 444 stainless steel is non cytotoxic. The corrosion resistance was studied by anodic polarization methods and electrochemical impedance spectroscopy (EIS), in a saline phosphate buffered solution (PBS) at 37 °C. The electronic properties of the passive film formed on AISI 444 SS were evaluated by the Mott-Schottky approach. All tested materials showed passivity in the PBS medium and the passive oxide film presented a duplex nature. The highest susceptibility to pitting corrosion was associated to the NeoM SS. This steel was also associated to the highest dopant concentration. The comparatively low levels of chromium (nearly 12.5%) and molybdenum (0.3%) of NeoM relatively to the other studied stainless steels are the probable cause of its lower corrosion resistance. The NeoM chemical composition does not match that of the SUS444 standards. The AISI 444 SS pitting resistance was equivalent to the ISO 5832-1 pointing out that it is a potential candidate for replacement of commercial ferromagnetic alloys used in dental prosthesis. (author)

  4. Evaluation of performance of AISI 444 steel for application in distillation towers; Avaliacao do desempenho do aco AISI 444 para aplicacao como 'lining' em torres de destilacao

    Guimaraes, R.F.; Miranda, H.C. de; Farias, J.P. [Universidade Federal do Ceara (DEMM/UFC), Fortaleza, CE (Brazil). Dept. de Engenharia Metalurgica e de Materiais. Lab. de Caracterizacao de Materiais], e-mail: rf.guimaraes@yahoo.com.br

    2008-07-01

    In this work, the behavior of the AISI 444 ferritic stainless steel submitted to thermal fatigue test and their corrosion resistance in heavy crude oil was evaluated. The AWS E309MoL-16 and E316L-17 weld metal was employed as filler metal. Plates of the AISI 444 were welded on ASTM A-516 Gr. 60 plates and submitted to fatigue thermal cycle. Samples were extracted from plates welded and heat treated immersed in heavy crude oil at 300 deg C. Optical microscopy (OM), scanning electron microscopy (SEM) and energy dispersive of X-ray analysis (EDX) were used to characterize the microstructure and the corroded surface. The results show that the AISI 444 stainless steels did not present cracks after the thermal fatigue cycle and the heat treated immerse in heavy crude oil. The electrode AWS E309MoL-16 show better corrosion resistance than the AWS E316L-17. (author)

  5. Coping strategies after heart transplantation: psychological implications Estratégias de enfrentamento pós-transplante cardíaco: implicações psicológicas

    Paula Moraes Pfeifer

    2013-03-01

    Full Text Available OBJECTIVES: To investigate coping strategies used by patients submitted to heart transplantation and whether they are related to the perception of the disease and transplantation. METHODS: Cross-sectional study with quantitative and qualitative analysis. The sample of 32 patients was assessed by the Ways of Coping Scale and socio-demographic questionnaire, and five of them were selected for interviews. The internal consistency of the scale was assessed, the variables and strategies involved were crossed and content analysis of interviews, investigating the existence of a relationship with the speech of the participants. RESULTS: The individuals have used all coping styles, with a predominance of the problem-focused strategy. Psychologically prepared patients showed a statistically significant increase in the use of problem-focused coping and seek for social support. However, a significant increase in the use of emotion-focused coping was observed in patients who were not prepared. Analysis through the method of Bardin showed as categories: disease; reaction to call; transplantation; fantasies; postoperative; team and coping. CONCLUSION: Patients with a transplanted heart make use of all coping strategies, with a predominance of the problem-focused strategy. Psychologically prepared individuals used more active coping strategies, which highlights the importance of psychological support during the process.OBJETIVOS: Verificar as estratégias de enfrentamento utilizadas por indivíduos que tiveram o coração transplantado e suas relações com percepção da doença e do transplante. MÉTODOS: Estudo transversal com análise quantitativa e qualitativa. A amostra de 32 pacientes foi avaliada pela Escala Modos de Enfretamento de Problemas e questionário sociodemográfico; e cinco deles foram sorteados para entrevista. Realizou-se a avaliação da consistência interna da escala, cruzamentos entre as variáveis e os estilos de enfrentamento e a análise de conteúdo das entrevistas, relacionando os resultados ao discurso dos participantes. RESULTADOS: Os indivíduos utilizaram todos os estilos de enfrentamento, predominando o focalizado no problema. Nos participantes que receberam preparo psicológico, houve aumento estatisticamente significativo dos enfrentamentos focalizados no problema e na busca de suporte social. Entretanto, naqueles que não receberam preparo, houve aumento significativo da utilização do enfrentamento focalizado na emoção. Através do método de Bardin, revelaram-se como categorias: doença, reação ao chamado, transplante, fantasias, pós-operatório, equipe e enfrentamento. CONCLUSÕES: Os participantes utilizaram todos os estilos de enfrentamento, predominando a estratégia focalizada no problema. Os que receberam preparo psicológico usaram maior número de estratégias de enfrentamento ativas, o que evidencia a importância do acompanhamento psicológico durante o processo.

  6. Análisis del ECG en monitorización ambulatoria para el diagnóstico cardíaco y la predicción de muerte cardíaca súbita

    Vázquez Seisdedos, Carlos Román

    2001-01-01

    La muerte cardíaca súbita (SCD) es uno de los desafíos más importantes de la cardiología moderna debido al elevado número de personas que fallecen repentinamente sin presentar síntomas previos. Una de las principales causas de la SCD es el infarto de miocardio(IM) pues se estima que el 75 % de las personas que fallecen súbitamente tienen un IM antiguo. El análisis del ECG superficial puede ayudar a prevenir la SCD porque la isquemia miocárdica, que suele preceder al IM, conlleva cambios en la...

  7. Inibição da corrente de cálcio tipo L por tramadol e enantiômeros em miócitos cardíacos de ratos

    Emiliano Medei; Juliana M. Raimundo; José Hamilton M. Nascimento; Margarete M. Trachez; Roberto T. Sudo; Gisele Zapata-Sudo

    2011-01-01

    FUNDAMENTO: O tramadol é um analgésico de ação central cujo mecanismo de ação envolve a ativação de um receptor opioide. Anteriormente, mostramos que o tramadol e seus enantiômeros apresentavam um efeito inotrópico negativo sobre o músculo papilar no qual o (+)-enantiômero era mais potente que (-)- e (±)-tramadol. OBJETIVO: No presente trabalho, investigamos os efeitos do tramadol e seus enantiômeros na corrente de cálcio tipo L (I Ca-L). MÉTODOS: Os experimentos foram realizados em miócitos ...

  8. Sliding wear of steels (used in polished rods of oil pump jack) against polyurethane; Desgaste de deslizamento de acos (usados em hastes de unidade de bombeio de petroleo) contra poliuretano

    Gois, Gelsoneide da Silva [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil). Engenharia de Materiais; Farias, Aline Cristina Mendes; Lima da Silva, Ruthilene Catarina; Medeiros, Joao Telesforo Nobrega [Universidade Federal do Rio Grande do Norte (PPGEM/UFRN), Natal, RN (Brazil). Programa de Pos-Graduacao em Engenharia de Materiais], e-mail: gelsoneidegg@yahoo.com.br, e-mail: alineastro@yahoo.com.br, e-mail: ruthilene@ufrnet.br, e-mail: medeirosj2@asme.org

    2008-07-01

    Accelerated sliding tests were carried out in the steels AISI 316, AISI 4140, AISI 1045 coated and AISI 4142 coated, in the dry and lubricated with contaminated oil with 10% SiO{sub 2} conditions. Each cylindrical counterbody with angular generatrix of polyurethane slid against a stationary metallic specimen. The contact pressure changed by increment of normal loads of 10,0 and 2,3 N, velocity of 0,91 m/s and distance of 12 km. The wear rates were calculated through of the mass variation from specimens after each test. The wear morphology was characterized by Optical and Scanning Electron Microscopy, where identified damages by abrasion at two and three bodies. The contaminated lubricant increase the wear rate due to action of the abrasive particles. (author)

  9. PPARα及Aco x1在酒精性脂肪肝中的表达∗%Expression of PPARαand Acox1 in Rats with Alcoholic Fatty Liver Disease

    仝巧云; 葛存锦; 郑世华

    2016-01-01

    Objective To investigate the molecular biological mechanism of deposition of triglyceride(TG)in hepatocytes in alcoholic fatty liver disease(AFLD)and the pathogenesis of this condition by detecting the contents of serum tumor necrosis fac-tor-α(TNF-α),liver triglyceride(TG),peroxisome proliferator-activated receptorα(PPARα)and acyl-CoA oxidase(Acox1)mR-NAs,and liver PPARαprotein after intervention with bezafibrate,a PPARαagonist.Methods Sixty Wistar rats were randomly divided into three groups:control group(n=20),AFLD group(n=20),and bezafibrate group(n=20).Animals in control group were given distilled water by gavage once a day for 8 weeks.Those in AFLD group were given ethanol and fish oil(2.5 mL/kg) by gavage daily for the same period of time.In bezafibrate group,rats were treated by gavage with ethanol and fish oil(2.5 mL/kg)for the first 4 weeks and then with bezafibrate(100 mg/kg)for another 4 weeks.TG in the liver was measured by colorimet-ric method,serum TNF-αlevels by enzyme linked immunoabsorbent assay (ELISA),the mRNA expression of PPARαand Acox1 in hepatocytes by reverse transcription polymerase chain reaction(RT-PCR)and the expression of PPARαprotein in hep-atocytes by Western blot.Results A significant increase in TG[AFLD group(0.72±0.09)mmol/L vs.control group(0.28± 0.07)mmol/L,P<0.01]and TNF-α[AFLD group(3.01±0.31)ng/mL vs.control group(1.07±0.28)ng/mL,P<0.01]was found in AFLD group when compared with control group.After bezafibrate intervention,the contents of liver TG and serum TNF-αwere significantly decreased.The mRNA expression of PPARα[AFLD group(0.22±0.08)vs.control group(0.68± 0.13),P<0.01]and Acox1[AFLD group(0.43±0.12)vs.control group(1.14±0.21),P<0.01]was suppressed in AFLD group,which was significantly reversed by bezafibrate treatment[bezafibrate group(0.59±0.13)for PPARαmRNA vs.AFLD group,P<0.01;bezafibrate group(0.83±0.17)for Acox1 mRNA vs.AFLD group,P<0.01].The expression of PPARαpro-tein in hepatocyts was also found to decrease in AFLD group[AFLD group(0.19±0.07)vs.control group(0.48±0.11),P<0.01].After bezafibrate intervention,it was profoundly increased.Conclusion The down-expression of PPARαand Acox1 in the liver of rats with AFLD may suppress the fatty acid metabolism and lead to the TG deposition in the liver.The increase in serum TNF-αcontents also contributes to the development of AFL.Bezafibrate can prevent and treat AFL by activating PPARα,increasing the expression of PPARαand Acox1 ,promoting the metabolism of fatty acids,decreasing the TG deposition and the serum TNF-αcontents.%目的:通过测定酒精性脂肪肝大鼠血清 TNF-α、肝内甘油三酯、PPARαmRNA 及 Acox1 mRNA 含量、肝内PPARα蛋白含量,并通过PPARα激动剂苯扎贝特(Bezafibrate)的干预研究,探讨酒精性脂肪肝大鼠肝内甘油三酯沉积的分子生物学机制及酒精性脂肪肝的发病机制。方法将60只 Wistar大鼠随机分为正常对照组(n=20)、酒精性脂肪肝组(n=20)及苯扎贝特组(n=20)。正常对照组予蒸馏水灌胃8周;酒精性脂肪肝组给予鱼油2.5 mL/kg+乙醇灌胃8周;苯扎贝特组采用鱼油+乙醇灌胃,4周后加用苯扎贝特100 mg/kg灌胃治疗4周。第8周取腹腔静脉血及肝组织,采用 ELISA法测定血清TNF-α含量;比色法测定肝脏甘油三酯沉积;RT-PCR 法测定肝内 PPARαmRNA 及 Acox1 mRNA含量;Western blot法测定肝内PPARα蛋白含量。结果与正常对照组相比,酒精性脂肪肝组大鼠血清内TNF-α含量升高[(3.01±0.31)ng/mL vs.(1.07±0.28)ng/mL,P<0.01],肝内甘油三酯沉积增多[(0.72±0.09)mmol/L vs.(0.28±0.07)mmol/L,P<0.01],肝内PPARαmRNA[(0.22±0.08)vs.(0.68±0.13),P<0.01]及 Acox1 mRNA [(0.43±0.12)vs.(1.14±0.21),P<0.01]表达减少,PPARα蛋白含量减少[(0.19±0.07)vs.(0.48±0.11),P<0.01]。经苯扎贝特治疗后,苯扎贝特组大鼠血清内 TNF-α含量降低,肝内甘油三酯沉积减少,肝内 PPARαmRNA 及Acox1 mRNA表达增多,PPARα蛋白含量增多。结论酒精性脂肪肝大鼠肝内 PPARα及 Acox1表达减少,从而影响脂肪酸的代谢,导致肝内甘油三酯沉积增多,血清内 TNF-α含量升高,引起酒精性脂肪肝。苯扎贝特可通过激活PPARα,使肝内PPARα及 Acox1表达增加,促进脂肪酸的代谢,减少肝内甘油三酯沉积,降低血清内 TNF-α含量,起到预防和治疗酒精性脂肪肝的作用。

  10. Contribuição para o estudo de alguns parâmetros na avaliação do trabalho cardíaco em cães e gatos

    Marques, Ana Margarida Grilo Nobre

    2010-01-01

    No âmbito do estágio curricular realizado no Instituto Veterinário do Parque desenvolveram-se actividades na área da Clínica e Cirurgia de animais de companhia. A Cardiologia foi uma das especialidades com maior expressão, o que permitiu o acompanhamento da execução de exames de diagnóstico cardiológico, em particular a ecocardiografia. Esta dissertação incide sobre quatro parâmetros ecocardiográficos, coeficiente átrio esquerdo/aorta (AE/Ao), distância do septo ao ponto E (EPSS), fracção de ...

  11. Traumatismo cardíaco com retenção de corpo estranho em criança de sete anos Cardiac trauma with retained pellets in a seven year-old child

    Fernando Antonio Campelo Spencer Netto

    1998-08-01

    Full Text Available This is a case report about a seven year-old child who arrived at Emergency Department of Hospital da Restauração with gunshot wound on precordial area and clinical signs of cardiac tamponade. The roentgenogram showed 27 retained pellets in cardiac area. Thoracotomy was performed and repaired a cardiac wound in right ventricule. The patient developed conduction disturbance and valvar defect, but was discharged on the tenth postoperative day. Diagnosis, treatment and complications of retained projectiles are discussed.

  12. Traumatismo cardíaco com retenção de corpo estranho em criança de sete anos Cardiac trauma with retained pellets in a seven year-old child

    Fernando Antonio Campelo Spencer Netto; Paulo Sérgio Vieira de Melo; Olavo Raimundo dos Santos Filho

    1998-01-01

    This is a case report about a seven year-old child who arrived at Emergency Department of Hospital da Restauração with gunshot wound on precordial area and clinical signs of cardiac tamponade. The roentgenogram showed 27 retained pellets in cardiac area. Thoracotomy was performed and repaired a cardiac wound in right ventricule. The patient developed conduction disturbance and valvar defect, but was discharged on the tenth postoperative day. Diagnosis, treatment and complications of retained ...

  13. Study of residual stresses in welded joints of dual phase HSLA steel used in automotive industry; Estudo das tensoes residuais em juntas soldadas de aco ARBL bifasico usado na industria automobilistica

    Barbato, D.S.; Fonseca, M.P. Cindra; Marques Junior, A.S.; Chuvas, T.C.; Pardal, J.M., E-mail: mcindra@vm.uff.b [Universidade Federal Fluminense (PGMEC/UFF), Niteroi, RJ (Brazil). Programa de Pos-graduacao em Engenharia Mecanica; Berretta, J.R. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2010-07-01

    One way of weight reduction in automotive vehicles is through the use of high strength and low alloy (HSLA) steels, which enables the use of small thickness plates. Whereas the appearance of residual stresses is intrinsic to the welding process, this study evaluates the residual stresses generated in welded joints obtained by TIG and LASER welding processes and comparing them. Residual stresses were measured by X-rays diffraction technique, using a portable device with Cr{kappa}{alpha} radiation applying the double exposure method. It also evaluates the influence of shot peening treatment applied after welding, in the bend tests conducted for both welding conditions and TIG welded joints showed higher stability of compressive stresses after welding. The metallographic analysis by optical microscopy complemented the welded joints characterization. (author)

  14. Influence of treatment by vibration in residual stress generated in the laser welding of HSLA and IF steels; Influencia do tratamento de vibracao nas tensoes residuais geradas na soldagem a laser de acos ARBL e IF

    Chuvas, T.C.; Fonseca, M.P. Cindra, E-mail: chuvas@vm.uff.b [Universidade Federal Fluminense (PGMEC/UFF), Niteroi, RJ (Brazil). Programa de Pos-graduacao em Engenharia Mecanica; Castello, D.A. [Universidade Federal do Rio de Janeiro (DEM/UFRJ), RJ (Brazil). Dept. de Engenharia Mecanica

    2010-07-01

    The stress relieving treatment by vibration is a new technology under development, which has many advantages over thermal methods. In this work was analyzed the surface residual stress generated in the laser welding of biphasic HSLA and IF steels, both used in the automotive industry. Residual stresses were measured by X-ray diffraction, by the sen{sup 2} {Psi} method. Residual stresses generated in the welding of the samples were tensile at all points measured. After welding, the samples were submitted to the mechanical vibration treatment. Some samples presented a significant reduction in the stress values. The welded joints were also characterized by optical microscopy. (author)

  15. Utilization of aluminum to obtaining a duplex type stainless steel using high energy ball milling; Obtencao de um aco inoxidavel de estrutura duplex do sistema FeMnAl processado por moagem de alta energia

    Pavlak, I.E.; Cintho, O.M., E-mail: eng.igorpavlak@yahoo.com.b [Universidade Estadual de Ponta Grossa (UEPG), PR (Brazil); Capocchi, J.D.T. [Universidade de Sao Paulo (USP), SP (Brazil)

    2010-07-01

    The obtaining of stainless steel using aluminum in its composition - FeMnAl system, has been researches subject since the sixties, by good mechanical properties and resistance to oxidation presented, when compared with conventional FeNiCr stainless steel system. In another point, the aluminum and manganese are low cost then traditional elements. This work, metallic powders of iron, manganese and pure aluminum, were processed in a Spex type high-energy ball mill in nitrogen atmosphere. The milling products were compressed into pastille form and sintered under inert atmosphere. The final products were characterized by optical and electronic microscopy and microhardness test. The metallographic analysis shows a typical austenite and ferrite duplex type microstructure. The presence of these phases was confirmed according X ray diffraction analysis. (author)

  16. Mechanical properties and weldability of steel bars for reinforcing concrete obtained by TEMPCORE process; Propriedades necanicas e soldabilidade de barras de aco para concreto armado fabricadas pelo processo Tempcore

    Paula e Silva, Adriano de; Cetlin, Paulo R.; Aguilar, Maria T. P. [Minas Gerais Univ., Belo Horizonte, MG (Brazil). Escola de Engenharia; Rodrigues, Paulo C. [Fundacao Universidade de Sao Joao Del Rey (FUNREI), MG (Brazil)

    1992-12-31

    TEMPCORE process consists of a controlled cooling steel bars after passing through the last roll stand. When using water under pressure, which was previously defined, low carbon content steel can be produced as well as other alloys elements, having similar properties to steel produced by conventional process. The TEMPCORE process is discussed and the mechanical properties of TEMPCORE bars are compared with the TEMPCORE bars welded by the process of sheathed electrodes. 4 refs., 8 figs., 4 tabs.

  17. Main radiation protection actions for medical personnel as primary responders front of an event with radiological dispersive device; Principais acoes de protecao radiologica para equipe medica como primeiros respondedores frente a um evento com dispositivo de dispersao radiologica

    Duque, Hildanielle Ramos

    2015-07-01

    After the terrorist attack in New York, USA, in 2001, there was a worldwide concern about possible attacks using radioactive material in conventional detonators, called as Radiological Dispersal Device (RDD) or 'dirty bomb'. Several studies have been and are being made to form a global knowledge about this type of event. As until now, fortunately, there has not been an event with RDD, the Goiania Radiological Accident in Brazil, 1987, is used as a reference for decision-making. Several teams with technical experts should act in an event with RDD, but the medical staffs who respond quickly to the event must be properly protected from the harmful effects of radiation. Based on the radiological protection experts performance during the Goiania accident and the knowledge from lessons learned of many radiological accidents worldwide, this work presents an adaptation of the radiation protection actions for an event with RDD that helps a medical team as primary responders. The following aspects are presented: the problem of radioactive contamination from the explosion of the device in underground environment, the actions of the first responders and evaluation of health radiation effects. This work was based on specialized articles and papers about radiological accidents and RDD; as well as personal communication and academic information of the Institute of Radiation Protection and Dosimetry. The radiation protection actions, adapted to a terrorist attack event with RDD, have as a scenario a subway station in the capital. The main results are: the use of the basic radiation protection principle of time because there is no condition to take care of a patient keeping distance or using a shielding; the use of full appropriate protection cloths for contaminating materials ensuring the physical safety of professionals, and the medical team monitoring at the end of a medical procedure, checking for surface contamination. The main conclusion is that all medical actions as primary responders must be followed up by radiation protection specialists. (author)

  18. Obtaining and analysis of results of fatigue and corrosion-fatigue in steel API 5L X60; Obtencao e analise de resultados de fadiga e corrosao-fadiga em aco API 5L X60

    Araujo, Bruno Allison [Universidade Federal de Campina Grande (UFCG), PB (Brazil). Programa de Pos-Graduacao em Ciencia e Engenharia de Materiais; Silva, Antonio Almeida; Santos, Fabio Gualberto Chagas [Universidade Federal de Campina Grande (UFCG), PB (Brazil)

    2008-07-01

    The corrosion process allied to the fatigue, due to repetitive efforts of several natures, is the main responsible for the damages in pipeline and offshore structures that results in the appears of located faults, and by the way can results in leaks and financial and environmental loss. This phenomenon calls corrosion-fatigue, however, it is very complex, and mainly, in what it concerns the form as this it develops in the structure. The objective of this work is to present some results of experimental fatigue tests and corrosion-fatigue accomplished with specimen that the material originated a pipeline steel API 5L X60. The tests developed in a machine which could test until 12 specimens per time. For test of corrosion-fatigue was used a cell-of-corrosion especially projected, in this way simulated an aggressive environmental condition in a corrosion conditions. With the results of tests, was possible estimate the fatigue limits of the specimen when submitted to the repeated flexing, and compare it with evaluate corrosion-fatigue graphs, that as the literature comes moved down of the curve, in relation to the fatigue curve. (author)

  19. Plasma sintering of ferritic steel reinforced with niobium carbide prepared by high energy milling; Sinterizacao a plasma de aco ferritico reforcado com carbeto de niobio preparado por moagem de alta energia

    Silva Junior, J.F. da; Almeida, E.O.; Gomes, U.U.; Alves Junior, C.; Messias, A.P. [Universidade Federal do Rio Grande do Norte (UFRN), Natal (Brazil). Lab. de Materiais Ceramicos e Metais Especiais; Universidade Federal do Rio Grande do Norte (UFRN), Natal (Brazil). Lab. de Processamento de Materiais por Plasma

    2010-07-01

    Plasma is an ionized gas where ions are accelerated from anode to cathode surface, where the sample is placed. There are a lot of collisions on cathode surface by ions heating and sintering the sample. High energy milling (HEM) is often used to produce composite particles to be used on powder metallurgy. These particles can exhibit fine particles and high phase dispersion. This present work aim to study ferritic steels reinforced with 3%NbC prepared by HEM and sintered on plasma furnace. Ferritic steel and NbC powders were milled during 5 hours and characterized by SEM, XRD and laser scattering. Then, these composite powders were compacted in a cylindrical steel die and then sintered in a plasma furnace. Vickers microhardness tests and SEM and XRD analysis were performed on sintered samples. (author)

  20. Experiment Study of Entropy Convergence of Ant Colony Optimization

    Pang, Chao-Yang; Wang, Chong-Bao; Hu, Ben-Qiong

    2009-01-01

    Ant colony optimization (ACO) has been applied to the field of combinatorial optimization widely. But the study of convergence theory of ACO is rare under general condition. In this paper, the authors try to find the evidence to prove that entropy is related to the convergence of ACO, especially to the estimation of the minimum iteration number of convergence. Entropy is a new view point possibly to studying the ACO convergence under general condition. Key Words: Ant Colony Optimization, Conv...

  1. Avaliação da ansiedade e depressão no período pré-operatório em pacientes submetidos a procedimentos cardíacos invasivos Evaluación de la ansiedad y depresión en el período preoperatorio en pacientes sometidos a procedimientos cardíacos Evaluation of preoperative anxiety and depression in patients undergoing invasive cardiac procedures

    Antonio Fernando Carneiro

    2009-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A avaliação específica da ansiedade e da depressão não está incluída na rotina de avaliação pré-operatória, o que faz com que em situações como as doenças cardíacas, em que o estado emocional dos pacientes pode estar modificado pela própria doença, possam não ser diagnosticadas. O objetivo do estudo foi comparar o nível e a prevalência de ansiedade e depressão em pacientes com doença cardíaca a serem submetidos a procedimentos invasivos e/ou cirúrgicos, utilizando a Escala Hospitalar de Ansiedade e Depressão (Hospital Anxiety and Depression Scale - HAD. MÉTODO: Após a aprovação pelos Comitês de Ética, foram incluídos 96 pacientes, estado físico ASA II e III, que constituíram três grupos: estudo eletrofisiológico (EEF, implante de marcapasso (MP e revascularização do miocárdio (RM. Os escores considerados "ponto de corte" foram: escala HAD-ansiedade (HAD-A com ansiedade > 9; escala HAD-depressão (HAD-D com depressão > 9. RESULTADOS: Os grupos foram homogêneos quanto às variáveis sociodemográficas. Observou-se diferença estatística significativa entre os três grupos (p = 0,006; p = 0,034 quanto ao nível e prevalência de ansiedade (HAD-A e na comparação do nível de ansiedade grupo a grupo verificou-se diferença significativa entre os grupos EEF × RM e EEF × MP (p JUSTIFICATIVA Y OBJETIVOS: La evaluación específica de la ansiedad y de la depresión no está incluida en la rutina de evaluación preoperatoria, lo que hace con que en algunas situaciones como las enfermedades cardiacas, en que el estado emocional de los pacientes puede estar modificado por la propia enfermedad, puedan no quedar diagnosticadas. El objetivo del estudio fue comparar el nivel y la prevalencia de ansiedad y depresión en pacientes con enfermedad cardiaca a ser sometidos a procedimientos invasivos y/o quirúrgicos, utilizando la Escala Hospitalaria de Ansiedad y Depresión (Hospital Anxiety and Depression Scale - HAD. MÉTODO: Después de la aprobación por parte de los Comités de Ética, se incluyeron 96 pacientes, estado físico ASA II y III, que constituyeron tres grupos: estudio electrofisiológico (EEF, implante de marcapaso (MP y revascularización del miocardio (RM. Las puntuaciones consideradas "punto de corte" fueron las siguientes: escala HAD-ansiedad (HAD-A: con ansiedad > 9; escala HAD-depresión (HAD-D: con depresión > 9. RESULTADOS: Los grupos fueron homogéneos en cuanto a las variables sociodemográficas. Se observó una diferencia estadística significativa entre los tres grupos (p = 0,006; p = 0,034 en lo concerniente al nivel y a la prevalencia de ansiedad (HAD-A y en la comparación del nivel de ansiedad grupo a grupo, se verificó la diferencia significativa entre los grupos EEF x RM y EEF x MP (p BACKGROUND AND OBJECTIVES: Specific assessment of anxiety and depression is not included in routine preoperative evaluation; therefore, in cases of cardiac diseases in which the emotional status of the patient may be modified by the disease those disorders may not be diagnosed. The objective of the present study was to compare the level and prevalence of anxiety and depression in patients with cardiac disease undergoing invasive and/or surgical procedures using the Hospital Anxiety and Depression Scale - HAD. METHODS: After approval by the Ethics Committee, 96 patients, physical status ASA II and III, were divided in three groups: electrophysiological study (EPS, pacemaker (PM placement, and myocardial revascularization (MR. "Cutting points" were as follows: HAD-anxiety scale (HAD-A with anxiety > 9; HAD-depression scale (HAD-D with depression > 9. RESULTS: All three groups were homogenous regarding sociodemographic parameters. Statistically significant differences were observed among the three groups (p = 0.006; p = 0.034 in the level and prevalence of anxiety (HAD-A; and in the intergroup comparison of the anxiety level significant differences were observed between the EPS x MR and EPS x PM groups (p < 0.05. Significant differences in the level and prevalence of depression (HAD-D among the study groups were not observed. CONCLUSIONS: Patients with cardiac diseases undergoing electrophysiological studies, pacemaker implantation, and myocardial revascularization have different levels and prevalence of anxiety, but they do not show differences in the level and prevalence of depression.

  2. Cloning and sequence of cDNA encoding 1-aminocyclo- propane-1-carboxylate oxidase in Vanda flowers

    Pattana Srifah Huehne

    2013-08-01

    Full Text Available The 1-aminocyclopropane-1-carboxylate oxidase (ACO gene in the final step of ethylene biosynthesis was isolated from ethylene-sensitive Vanda Miss Joaquim flowers. This consists of 1,242 base pairs (bp encoding for 326 amino acid residues. To investigate the specific divergence in orchid ACO sequences, the deduced Vanda ACO was aligned with five other orchid ACOs. The results reveal that the ACO sequences within Doritaenopsis, Phalaenopsis and Vanda show highly conserved and almost 95% identical homology, while the ACOs isolated from Cymbidium, Dendrobium and Cattleya are 8788% identical to Vanda ACO. In addition, the 2-oxoglutarate- Fe(II_oxygenase (Oxy domain of orchid ACOs consists of a higher degree of amino acid conservation than that of the non-haem dioxygenase (DIOX_N domain. The overall homology regions of Vanda ACO are commonly folded into 12 α-helices and 12 β-sheets similar to the three dimensional template-structure of Petunia ACO. This Vanda ACO cloned gene is highly expressed in flower tissue compared with root and leaf tissues. In particular, there is an abundance of ACO transcript accumulation in the column followed by the lip and the perianth of Vanda Miss Joaquim flowers at the fully-open stage.

  3. Novel Approach to Nonlinear PID Parameter Optimization Using Ant Colony Optimization Algorithm

    Duan Hai-bin; Wang Dao-bo; Yu Xiu-fen

    2006-01-01

    This paper presents an application of an Ant Colony Optimization (ACO) algorithm to optimize the parameters in the design of a type of nonlinear PID controller. The ACO algorithm is a novel heuristic bionic algorithm, which is based on the behaviour of real ants in nature searching for food. In order to optimize the parameters of the nonlinear PID controller using ACO algorithm,an objective function based on position tracing error was constructed, and elitist strategy was adopted in the improved ACO algorithm. Detailed simulation steps are presented. This nonlinear PID controller using the ACO algorithm has high precision of control and quick response.

  4. A HYBRID OPTIMIZATION ALGORITHM BASED ON GENETIC ALGORITHM AND ANT COLONY OPTIMIZATION

    Zainudin Zukhri

    2013-09-01

    Full Text Available In optimization problem, Genetic Algorithm (GA and Ant Colony Optimization Algorithm (ACO have been known as good alternative techniques. GA is designed by adopting the natural evolution process, while ACO is inspired by the foraging behaviour of ant species. This paper presents a hybrid GA-ACO for Travelling Salesman Problem (TSP, called Genetic Ant Colony Optimization (GACO. In this method, GA will observe and preserve the fittest ant in each cycle in every generation and only unvisited cities will be assessed by ACO. From experimental result, GACO performance is significantly improved and its time complexity is fairly equal compared to the GA and ACO.

  5. Novel method based on ant colony optimization for solving ill-conditioned linear systems of equations

    2005-01-01

    A novel method based on ant colony optimization (ACO), algorithm for solving the ill-conditioned linear systems of equations is proposed. ACO is a parallelized bionic optimization algorithm which is inspired from the behavior of real ants. ACO algorithm is first introduced, a kind of positive feedback mechanism is adopted in ACO. Then, the solution problem of linear systems of equations was reformulated as an unconstrained optimization problem for solution by an ACO algorithm. Finally, the ACO with other traditional methods is applied to solve a kind of multi-dimensional Hilbert ill-conditioned linear equations. The numerical results demonstrate that ACO is effective, robust and recommendable in solving ill-conditioned linear systems of equations.

  6. An Early Assessment of Accountable Care Organizations' Efforts to Engage Patients and Their Families.

    Shortell, Stephen M; Sehgal, Neil J; Bibi, Salma; Ramsay, Patricia P; Neuhauser, Linda; Colla, Carrie H; Lewis, Valerie A

    2015-10-01

    Accountable care organizations (ACOs) have incentives to meet quality and cost targets to share in any resulting savings. Achieving these goals will require ACOs to engage more actively with patients and their families. The extent to which ACOs do so is currently unknown. Using mixed methods, including a national survey, phone interviews, and site-visits, we examine the extent to which ACOs actively engage patients and their families, explore challenges involved, and consider approaches for dealing with those challenges. Results indicate that greater ACO use of patient activation and engagement (PAE) activities at the point-of-care may be related to positive perceptions among ACO leaders of the impact of PAE investments on ACO costs, quality, and outcomes of care. We identify a number of important practices associated with greater PAE, including high-level leadership commitment, goal-setting supported by adequate resources, extensive provider training, use of interdisciplinary care teams, and frequent monitoring and reporting on progress. PMID:26038349

  7. Variation In Accountable Care Organization Spending And Sensitivity To Risk Adjustment: Implications For Benchmarking.

    Rose, Sherri; Zaslavsky, Alan M; McWilliams, J Michael

    2016-03-01

    Spending targets (or benchmarks) for accountable care organizations (ACOs) participating in the Medicare Shared Savings Program must be set carefully to encourage program participation while achieving fiscal goals and minimizing unintended consequences, such as penalizing ACOs for serving sicker patients. Recently proposed regulatory changes include measures to make benchmarks more similar for ACOs in the same area with different historical spending levels. We found that ACOs vary widely in how their spending levels compare with those of other local providers after standard case-mix adjustments. Additionally adjusting for survey measures of patient health meaningfully reduced the variation in differences between ACO spending and local average fee-for-service spending, but substantial variation remained, which suggests that differences in care efficiency between ACOs and local non-ACO providers vary widely. Accordingly, measures to equilibrate benchmarks between high- and low-spending ACOs--such as setting benchmarks to risk-adjusted average fee-for-service spending in an area--should be implemented gradually to maintain participation by ACOs with high spending. Use of survey information also could help mitigate perverse incentives for risk selection and upcoding and limit unintended consequences of new benchmarking methodologies for ACOs serving sicker patients. PMID:26953298

  8. An Ant Colony Optimization Based Dimension Reduction Method for High-Dimensional Datasets

    Ying Li; Gang Wang; Huiling Chen; Lian Shi; Lei Qin

    2013-01-01

    In this paper,a bionic optimization algorithm based dimension reduction method named Ant Colony Optimization -Selection (ACO-S) is proposed for high-dimensional datasets.Because microarray datasets comprise tens of thousands of features (genes),they are usually used to test the dimension reduction techniques.ACO-S consists of two stages in which two well-known ACO algorithms,namely ant system and ant colony system,are utilized to seek for genes,respectively.In the first stage,a modified ant system is used to filter the nonsignificant genes from high-dimensional space,and a number of promising genes are reserved in the next step.In the second stage,an improved ant colony system is applied to gene selection.In order to enhance the search ability of ACOs,we propose a method for calculating priori available heuristic information and design a fuzzy logic controller to dynamically adjust the number of ants in ant colony system.Furthermore,we devise another fuzzy logic controller to tune the parameter (q0) in ant colony system.We evaluate the performance of ACO-S on five microarray datasets,which have dimensions varying from 7129 to 12000.We also compare the performance of ACO-S with the results obtained from four existing well-known bionic optimization algorithms.The comparison results show that ACO-S has a notable ability to generate a gene subset with the smallest size and salient features while yielding high classification accuracy.The comparative results generated by ACO-S adopting different classifiers are also given.The proposed method is shown to be a promising and effective tool for mining high-dimension data and mobile robot navigation.

  9. Using health information technology to manage a patient population in accountable care organizations.

    Wu, Frances M; Rundall, Thomas G; Shortell, Stephen M; Bloom, Joan R

    2016-06-20

    Purpose - The purpose of this paper is to describe the current landscape of health information technology (HIT) in early accountable care organizations (ACOs), the different strategies ACOs are using to develop HIT-based capabilities, and how ACOs are using these capabilities within their care management processes to advance health outcomes for their patient population. Design/methodology/approach - Mixed methods study pairing data from a cross-sectional National Survey of ACOs with in-depth, semi-structured interviews with leaders from 11 ACOs (both completed in 2013). Findings - Early ACOs vary widely in their electronic health record, data integration, and analytic capabilities. The most common HIT capability was drug-drug and drug-allergy interaction checks, with 53.2 percent of respondents reporting that the ACO possessed the capability to a high degree. Outpatient and inpatient data integration was the least common HIT capability (8.1 percent). In the interviews, ACO leaders commented on different HIT development strategies to gain a more comprehensive picture of patient needs and service utilization. ACOs realize the necessity for robust data analytics, and are exploring a variety of approaches to achieve it. Research limitations/implications - Data are self-reported. The qualitative portion was based on interviews with 11 ACOs, limiting generalizability to the universe of ACOs but allowing for a range of responses. Practical implications - ACOs are challenged with the development of sophisticated HIT infrastructure. They may benefit from targeted assistance and incentives to implement health information exchanges with other providers to promote more coordinated care management for their patient population. Originality/value - Using new empirical data, this study increases understanding of the extent of ACOs' current and developing HIT capabilities to support ongoing care management. PMID:27296880

  10. Effect of plant growth-promoting bacteria on the growth and fructan production of Agave americana L.

    De La Torre-Ruiz, Neyser; Ruiz-Valdiviezo, Víctor Manuel; Rincón-Molina, Clara Ivette; Rodríguez-Mendiola, Martha; Arias-Castro, Carlos; Gutiérrez-Miceli, Federico Antonio; Palomeque-Dominguez, Héctor; Rincón-Rosales, Reiner

    2016-01-01

    The effect of plant growth-promoting bacteria inoculation on plant growth and the sugar content in Agave americana was assessed. The bacterial strains ACO-34A, ACO-40, and ACO-140, isolated from the A. americana rhizosphere, were selected for this study to evaluate their phenotypic and genotypic characteristics. The three bacterial strains were evaluated via plant inoculation assays, and Azospirillum brasilense Cd served as a control strain. Phylogenetic analysis based on the 16S rRNA gene showed that strains ACO-34A, ACO-40 and ACO-140 were Rhizobium daejeonense, Acinetobacter calcoaceticus and Pseudomonas mosselii, respectively. All of the strains were able to synthesize indole-3-acetic acid (IAA), solubilize phosphate, and had nitrogenase activity. Inoculation using the plant growth-promoting bacteria strains had a significant effect (pagave plants with proper biological characteristics for agroindustrial and biotechnological use and to increase the sugar content in this agave species. PMID:27268113

  11. Ant colony optimization approaches to clustering of lung nodules from CT images.

    Gopalakrishnan, Ravichandran C; Kuppusamy, Veerakumar

    2014-01-01

    Lung cancer is becoming a threat to mankind. Applying machine learning algorithms for detection and segmentation of irregular shaped lung nodules remains a remarkable milestone in CT scan image analysis research. In this paper, we apply ACO algorithm for lung nodule detection. We have compared the performance against three other algorithms, namely, Otsu algorithm, watershed algorithm, and global region based segmentation. In addition, we suggest a novel approach which involves variations of ACO, namely, refined ACO, logical ACO, and variant ACO. Variant ACO shows better reduction in false positives. In addition we propose black circular neighborhood approach to detect nodule centers from the edge detected image. Genetic algorithm based clustering is performed to cluster the nodules based on intensity, shape, and size. The performance of the overall approach is compared with hierarchical clustering to establish the improvisation in the proposed approach. PMID:25525455

  12. Ant Colony Optimization Approaches to Clustering of Lung Nodules from CT Images

    Ravichandran C. Gopalakrishnan

    2014-01-01

    Full Text Available Lung cancer is becoming a threat to mankind. Applying machine learning algorithms for detection and segmentation of irregular shaped lung nodules remains a remarkable milestone in CT scan image analysis research. In this paper, we apply ACO algorithm for lung nodule detection. We have compared the performance against three other algorithms, namely, Otsu algorithm, watershed algorithm, and global region based segmentation. In addition, we suggest a novel approach which involves variations of ACO, namely, refined ACO, logical ACO, and variant ACO. Variant ACO shows better reduction in false positives. In addition we propose black circular neighborhood approach to detect nodule centers from the edge detected image. Genetic algorithm based clustering is performed to cluster the nodules based on intensity, shape, and size. The performance of the overall approach is compared with hierarchical clustering to establish the improvisation in the proposed approach.

  13. Medicare Program; Medicare Shared Savings Program; Accountable Care Organizations--Revised Benchmark Rebasing Methodology, Facilitating Transition to Performance-Based Risk, and Administrative Finality of Financial Calculations. Final rule.

    2016-06-10

    Under the Medicare Shared Savings Program (Shared Savings Program), providers of services and suppliers that participate in an Accountable Care Organization (ACO) continue to receive traditional Medicare fee-for-service (FFS) payments under Parts A and B, but the ACO may be eligible to receive a shared savings payment if it meets specified quality and savings requirements. This final rule addresses changes to the Shared Savings Program, including: Modifications to the program's benchmarking methodology, when resetting (rebasing) the ACO's benchmark for a second or subsequent agreement period, to encourage ACOs' continued investment in care coordination and quality improvement; an alternative participation option to encourage ACOs to enter performance-based risk arrangements earlier in their participation under the program; and policies for reopening of payment determinations to make corrections after financial calculations have been performed and ACO shared savings and shared losses for a performance year have been determined. PMID:27295736

  14. Ant Colony Optimization Analysis on Overall Stability of High Arch Dam Basis of Field Monitoring

    Peng Lin; Xiaoli Liu; Hong-Xin Chen; Jinxie Kim

    2014-01-01

    A dam ant colony optimization (D-ACO) analysis of the overall stability of high arch dams on complicated foundations is presented in this paper. A modified ant colony optimization (ACO) model is proposed for obtaining dam concrete and rock mechanical parameters. A typical dam parameter feedback problem is proposed for nonlinear back-analysis numerical model based on field monitoring deformation and ACO. The basic principle of the proposed model is the establishment of the objective function o...

  15. A Hybrid Optimization Algorithm based on Genetic Algorithm and Ant Colony Optimization

    Zainudin Zukhri; Irving Vitra Paputungan

    2013-01-01

    In optimization problem, Genetic Algorithm (GA) and Ant Colony Optimization Algorithm (ACO) have been known as good alternative techniques. GA is designed by adopting the natural evolution process, while ACO is inspired by the foraging behaviour of ant species. This paper presents a hybrid GA-ACO for Travelling Salesman Problem (TSP), called Genetic Ant Colony Optimization (GACO). In this method, GA will observe and preserve the fittest ant in each cycle in every generation and on...

  16. Effect of plant growth-promoting bacteria on the growth and fructan production of Agave americana L.

    De La Torre-Ruiz, Neyser; Ruiz-Valdiviezo, Víctor Manuel; Rincón-Molina, Clara Ivette; Rodríguez-Mendiola, Martha; Arias-Castro, Carlos; Gutiérrez-Miceli, Federico Antonio; Palomeque-Dominguez, Héctor; Rincón-Rosales, Reiner

    2016-01-01

    The effect of plant growth-promoting bacteria inoculation on plant growth and the sugar content in Agave americana was assessed. The bacterial strains ACO-34A, ACO-40, and ACO-140, isolated from the A. americana rhizosphere, were selected for this study to evaluate their phenotypic and genotypic characteristics. The three bacterial strains were evaluated via plant inoculation assays, and Azospirillum brasilense Cd served as a control strain. Phylogenetic analysis based on the 16S rRNA gene sh...

  17. Improved Ant Algorithms for Software Testing Cases Generation

    Shunkun Yang; Tianlong Man; Jiaqi Xu

    2014-01-01

    Existing ant colony optimization (ACO) for software testing cases generation is a very popular domain in software testing engineering. However, the traditional ACO has flaws, as early search pheromone is relatively scarce, search efficiency is low, search model is too simple, positive feedback mechanism is easy to porduce the phenomenon of stagnation and precocity. This paper introduces improved ACO for software testing cases generation: improved local pheromone update strategy for ant colony...

  18. Apply Ant Colony Algorithm to Search All Extreme Points of Function

    Pang, Chao-Yang; Liu, Hui; Li, Xia; Wang, Yun-fei; Hu, Ben-Qiong

    2009-01-01

    To find all extreme points of multimodal functions is called extremum problem, which is a well known difficult issue in optimization fields. Applying ant colony optimization (ACO) to solve this problem is rarely reported. The method of applying ACO to solve extremum problem is explored in this paper. Experiment shows that the solution error of the method presented in this paper is less than 10^-8. keywords: Extremum Problem; Ant Colony Optimization (ACO)

  19. TABU SEARCH SEBAGAI LOCAL SEARCH PADA ALGORITMA ANT COLONY UNTUK PENJADWALAN FLOWSHOP

    Iwan Halim Sahputra

    2009-01-01

    Full Text Available Ant colony optimization (ACO is one of the meta-heuristic methods developed for finding solutions to optimization problems such as scheduling. Local search method is one part of the ACO which determines the quality of the resulting solution. In this paper, Tabu Search was proposed as a method of local search in ACO to solve the problem of flowshop scheduling. The purpose of this scheduling was to minimize the makespan. Makespan and computation time of the proposed method were compared to the ACO that implemented Job-Index as local search method. Using proposed algorithm, makespan values obtained were not significantly different than solutions of ACO using Job-Index method, and had computation time shorter. Abstract in Bahasa Indonesia: Ant colony optimization (ACO adalah salah satu metode meta-heuristic yang dikembangkan untuk mencari solusi bagi permasalahan optimasi seperti penjadwalan. Metode local search merupakan salah satu bagian dari ACO yang menentukan kualitas solusi yang dihasilkan. Dalam makalah ini Tabu Search diusulkan sebagai metode local search dalam algoritma ACO untuk menyelesaikan masalah penjadwalan flowshop. Tujuan dari penjadwalan ini adalah untuk meminimalkan makespan. Hasil makespan dan computation time dari metode usulan ini akan dibandingkan dengan algoritma ACO yang menggunakan Job-Index sebagai metode local search. Dengan menggunakan algoritma Tabu Search sebagai local search didapat nilai makespan yang tidak berbeda secara signifikan dibandingkan yang menggunakan metode Job-Index, dengan kelebihan computation time yang lebih singkat. Kata kunci: Tabu Search, Ant Colony Algorithm, Local Search, Penjadwalan Flowshop.

  20. PAPR reduction techniques for asymmetrically clipped optical OFDM communication system

    Wang, Yong; Zhang, Zhaojun; Sun, Lu

    2014-07-01

    In the ultraviolet communication system, ACO-OFDM technology can effectively suppress inter-symbol interference on the system performance, and further improve the transmission rate of the system. However, ACO-OFDM has a high peak to average power ratio (PAPR), and high PAPR not only reduces the power efficiency of the optical modulator, but also bring damage to the human eye or skin. In order to solve the above problem, according to ACO-OFDM signal characteristics, two clipping and filtering algorithms are used, and its performance is simulated, the simulations show that the two algorithms are able to inhibit well the PAPR of ACO-OFDM system.

  1. Comparison of Healthcare Quality Outcomes Between Accountable Care Organizations and Physician Group Practices.

    Singh, Sukhchain; Khosla, Sandeep; Sethi, Ankur

    2015-01-01

    Accountable Care Organizations (ACOs) were created under the Affordable Care Act to deliver better quality of care at reduced cost compare with the traditional fee-for-service model. But their effectiveness in achieving healthcare quality metrics is unclear. We analyzed ACO and physician group practice (PGP) performance rates for the single coronary artery disease measure and four diabetes mellitus measures now publicly reported on the Medicare Physician Compare Web site for program year 2012. There was no statistically significant difference in reported quality measures between ACOs and PGPs. Our study shows that PGPs can achieve outcomes at par with ACOs. PMID:26223106

  2. Ant colony optimization for bearings-only maneuvering target tracking in sensors network

    Benlian XU; Zhiquan WANG; Zhengyi WU

    2007-01-01

    In this paper, the problem of bearings-only maneuvering target tracking in sensors network is investigated.Two objectives are proposed and optimized by the ant colony optimization (ACO), then two kinds of node searching strategies of the ACO algorithm are presented. On the basis of the nodes determined by the ACO algorithm, the interacting multiple models extended Kalman filter (IMMEKF) for the multi-sensor bearings-only maneuvering target tracking is introduced. Simulation results indicate that the proposed ACO algorithm performs better than the Closest Nodes method.Furthermore, the Strategy 2 of the two given strategies is preferred in terms of the requirement of real time.

  3. Inverse estimation of the spheroidal particle size distribution using Ant Colony Optimization algorithms in multispectral extinction technique

    He, Zhenzong; Qi, Hong; Wang, Yuqing; Ruan, Liming

    2014-10-01

    Four improved Ant Colony Optimization (ACO) algorithms, i.e. the probability density function based ACO (PDF-ACO) algorithm, the Region ACO (RACO) algorithm, Stochastic ACO (SACO) algorithm and Homogeneous ACO (HACO) algorithm, are employed to estimate the particle size distribution (PSD) of the spheroidal particles. The direct problems are solved by the extended Anomalous Diffraction Approximation (ADA) and the Lambert-Beer law. Three commonly used monomodal distribution functions i.e. the Rosin-Rammer (R-R) distribution function, the normal (N-N) distribution function, and the logarithmic normal (L-N) distribution function are estimated under dependent model. The influence of random measurement errors on the inverse results is also investigated. All the results reveal that the PDF-ACO algorithm is more accurate than the other three ACO algorithms and can be used as an effective technique to investigate the PSD of the spheroidal particles. Furthermore, the Johnson's SB (J-SB) function and the modified beta (M-β) function are employed as the general distribution functions to retrieve the PSD of spheroidal particles using PDF-ACO algorithm. The investigation shows a reasonable agreement between the original distribution function and the general distribution function when only considering the variety of the length of the rotational semi-axis.

  4. Changes in Patients’ Experiences in Medicare Accountable Care Organizations

    McWilliams, J. Michael; Landon, Bruce E.; Chernew, Michael E.; Zaslavsky, Alan M.

    2014-01-01

    BACKGROUND Incentives for accountable care organizations (ACOs) to limit health care use and improve quality may enhance or hurt patients’ experiences with care. METHODS Using Consumer Assessment of Healthcare Providers and Systems (CAHPS) survey data covering 3 years before and 1 year after the start of Medicare ACO contracts in 2012 as well as linked Medicare claims, we compared patients’ experiences in a group of 32,334 fee-for-service beneficiaries attributed to ACOs (ACO group) with those in a group of 251,593 beneficiaries attributed to other providers (control group), before and after the start of ACO contracts. We used linear regression and a difference-in-differences analysis to estimate changes in patients’ experiences in the ACO group that differed from concurrent changes in the control group, with adjustment for the sociodemographic and clinical characteristics of the patients. RESULTS After ACO contracts began, patients’ reports of timely access to care and their primary physicians’ being informed about specialty care differentially improved in the ACO group, as compared with the control group (P = 0.01 and P = 0.006, respectively), whereas patients’ ratings of physicians, interactions with physicians, and overall care did not differentially change. Among patients with multiple chronic conditions and high predicted Medicare spending, overall ratings of care differentially improved in the ACO group as compared with the control group (P = 0.02). Differential improvements in timely access to care and overall ratings were equivalent to moving from average performance among ACOs to the 86th to 98th percentile (timely access to care) and to the 82nd to 96th percentile (overall ratings) and were robust to adjustment for group differences in trends during the preintervention period. CONCLUSIONS In the first year, ACO contracts were associated with meaningful improvements in some measures of patients’ experience and with unchanged performance in

  5. Functional Expression of the Thiolase Gene thl from Clostridium beijerinckii P260 in Lactococcus lactis and Lactobacillus buchneri

    The first step of the butanol pathway involves an acetyl-CoA acetyltransferase (ACoAAT), which controls the key branching point from acetyl-CoA to butanol. ACoAAT, also known as thiolase (EC 2.3.1.9), is encoded by the thl gene and catalyzes ligation of 2 acetyl-CoA into acetoacetyl-CoA. Bioinform...

  6. Size and albedo distributions of asteroids in cometary orbits using WISE data

    Licandro, J; Tancredi, G; Fernandez, Y

    2015-01-01

    We study the distributions of effective diameter ($D$), beaming parameter ($\\eta$), and visible geometric albedo ($p_V$) of asteroids in cometry orbits (ACOs) populations, derived from NASA's Wide-field Infrared Explorer (WISE) observations, and compare these with the same, independently determined properties of the comets. The near-Earth asteroid thermal model (NEATM) is used to compute the $D$, $p_V$ and $\\eta$. We obtained $D$ and $p_V$ for 49 ACOs in Jupiter family cometary orbits (JF-ACOs) and 16 ACOs in Halley-type orbits (Damocloids). We also obtained $\\eta$ for 45 of them. All but three JF-ACOs (95% of the sample) present a low albedo compatible with a cometary origin. The $p_V$ and $\\eta$ distributions of both ACO populations are very similar. For the entire sample of ACOs, the mean geometric albedo is $\\bar{p_V} = 0.05 \\pm 0.02$, ($\\bar{p_V} = 0.05 \\pm 0.01$ and $\\bar{p_V} =0.05 \\pm 0.02$ for JF-ACOs and Damocloids, respectively) compatible with a narrow albedo distribution similar to that of the Ju...

  7. Item Selection for the Development of Short Forms of Scales Using an Ant Colony Optimization Algorithm

    Leite, Walter L.; Huang, I-Chan; Marcoulides, George A.

    2008-01-01

    This article presents the use of an ant colony optimization (ACO) algorithm for the development of short forms of scales. An example 22-item short form is developed for the Diabetes-39 scale, a quality-of-life scale for diabetes patients, using a sample of 265 diabetes patients. A simulation study comparing the performance of the ACO algorithm and…

  8. The March to Accountable Care Organizations--How Will Rural Fare?

    MacKinney, A. Clinton; Mueller, Keith J.; McBride, Timothy D.

    2011-01-01

    Purpose: This article describes a strategy for rural providers, communities, and policy makers to support or establish accountable care organizations (ACOs). Methods: ACOs represent a new health care delivery and provider payment system designed to improve clinical quality and control costs. The Patient Protection and Affordable Care Act (ACA)…

  9. 77 FR 4632 - Defense Federal Acquisition Regulation Supplement; Independent Research and Development Technical...

    2012-01-30

    .... SUPPLEMENTARY INFORMATION: I. Background DoD published a proposed rule at 76 FR 11414 on March 2, 2011, to... interest to DoD, but fails to consider needed technical expertise. ACOs have responsibility for determining... officer (ACO) and the cognizant Defense Contract Audit Agency auditor to support the allowability of...

  10. Ant Colony Optimization and the Minimum Cut Problem

    Kötzing, Timo; Lehre, Per Kristian; Neumann, Frank;

    2010-01-01

    Ant Colony Optimization (ACO) is a powerful metaheuristic for solving combinatorial optimization problems. With this paper we contribute to the theoretical understanding of this kind of algorithm by investigating the classical minimum cut problem. An ACO algorithm similar to the one that was proved...

  11. Influência do nível de ruídos na percepção do estresse em pacientes cardíacos The influence of noise levels on the perception of stress in heart disease patients

    Aline Maria Heidemann

    2011-03-01

    Full Text Available OBJETIVO: Identificar os principais fatores geradores de estresse em pacientes internados em unidade coronariana e a influência do nível de ruídos na percepção de estresse dos mesmos. MÉTODOS: Estudo prospectivo, descritivo e quantitativo, realizado de junho a novembro de 2009 na Unidade Coronariana do Hospital de Clínicas da Unicamp. Para identificar os fatores estressantes foi utilizada a Escala de Estressores em Unidade de Terapia Intensiva (Intensive Care Unit Environmental Stressor Scale ICUESS no primeiro, segundo e terceiro dias de internação. Na primeira e segunda noite de internação, foi mensurado o nível de ruído pelo decibelímetro marca Instrutherm - modelo DEC-460. RESULTADOS: Participaram do estudo 32 pacientes cardiopatas clínicos. A mediana para a Escala de Estressores em Unidade de Terapia Intensiva foi de 67,5, 60,5 e 59,5, no primeiro, segundo e terceiro dias respectivamente, não apresentando diferença estatisticamente significante entre os valores. O maior valor de nível de ruídos foi às 21 horas, da segunda noite com mediana de 58,7dB, e o me-nor, de 51,5dB à zero hora da primeira noite. Quando feita a regressão linear múltipla, o nível de ruídos da primeira noite teve correlação de 33% com a Escala de Estressores do segundo dia, e o nível de ruídos da segunda noite teve correlação de 32,8% com a Escala de Estressores do terceiro dia, com p=0,001. CONCLUSÃO: Pacientes internados em Unidade Coronariana apresentam maior percepção de estresse. O elevado nível de ruídos também é responsável pela percepção do estresse dos pacientes.OBJECTIVES: To identify the main causes of stress in patients staying in a coronary unit and to assess the influence of noise levels on their perception of stress. METHODS: This was a prospective, descriptive and quantitative study conducted between June and November 2009 in the Coronary Unit of the Hospital de Clínicas da Universidade Estadual de Campinas. The Intensive Care Unit Environmental Stressor Scale was used on the first, second and third days of hospitalization to identify stressors. The noise level was measured on the first and second nights using an Instrutherm DEC-460 decibel meter. RESULTS: Overall, 32 clinical heart disease patients were included. The median Intensive Care Unit Environmental Stressor Scale scores were 67.5, 60.5 and 59.5 for the first, second and third days, respectively. The differences were not statistically significant. The highest noise level (a median of 58.7 dB was detected on the second night at 9:00 pm; the lowest level (51.5 dB was measured on the first night at 12:00 am. In a multiple linear regression model, the first-night noise level had a 33% correlation with the second-day stress scale score, and for the second night, the correlation with the third-day stress scale score was 32.8% (p = 0.001. CONCLUSION: Patients admitted into a coronary unit have an increased perception of stress. Higher noise levels are also responsible for the perception of stress in these patients.

  12. Presión parcial de oxígeno, pH, hematocrito, hemoglobina e índice cardíaco en pollos de engorde a 2.600 metros sobre el nivel del mar Arterial blood oxygen partial pressure, hematocrit, haemoglobin, and cardiac index in broilers at 2600 m above sea level

    E. JIMENEZ

    1998-01-01

    Full Text Available La incidencia de hipertensión arterial pulmonar (HP en pollosparrilleros constituye un problema económico importante. Dentrode los mecanismos de adaptación del organismo a la altitud se encuentran,además del aumento de la tensión arterial pulmonar, el incremento de la masa muscular ventricular derecha, la policitemía y posiblemente la hiperventilación con la subsecuente alcalosis respiratoria. Es factible que el alto nivel de energía en la ración incremente la hipoxemia derivada de la hipoxia; con lo anterior, el grado de policitemia se puede elevar y producirse un efecto agravante de la HP. Para establecer valores de pO2, Ht, Hb e IC en pollos parrilleros residentes a 2.600 m de altura sobre el nivel del mar, se estudiaron 24 aves de ambos sexos, de una población de 400 animales. Los valores promedios obtenidos fueron los siguientes: a pO2: 67.21 mmHg ± 5.21. Hubo diferencias estadísticas (pWideman y Buss (1985y Julian y col. (1985. La correlación inversa entre el IC y la pO2 arterial indican el efecto de la hipoxia de las vías aéreas en la hipoxemia y en el grado de hipertrofia e hiperplasia ventricular derecha.High incidence of cardiac failure in broilers due to hypoxic pulmonaryhypertension (PH, produces huge economical losses. Adaptive responsesinclude right ventricular hypertrophy and polycythemia. High energy levelin feed could increase hypoxemia and therefore the degree of polycythemia,thus increasing PH. To establish normal values in arterial oxygen partialpressure (pO2, pH, hematocrit (Ht, haemoglobin (Hb, and cardiacindex (CI, 24 broilers (12 males and 12 females, chosen at random, froma population of 400 birds, were studied in Bogotá, Colombia, 2600m above sea level. Mean values obtained were as follows: a pO2:67.21 ± 5.21 mmHg; statistical differences between sexes and among ages were found (p<0.05; b pH: 7.5 ± 0.05; c Ht: 37.13 ± 3.27%. In males, Ht values were higher at 24 and 37 days. In females, therewas a marked increment on day 31, but no significant differences were found (p<0.05. d Hb: 11.51 ± 1.37. e CI (right ventricular weight/total ventricular weight x 100: 26.6 ± 4.83. Highest values were found on day 31, being greater in the males. There were no statistical differences(p<0.05 between sexes or among ages for pH, Hb and CI. Hypoxemia is induced by environmental hypoxia and energy ingestion. Respiratory alcalosis was found, in comparison to data by other authors. The correlation found between pO2 and CI indicates that, in susceptible chickens hypoxemia due to airways hypoxia induces PH and therefore there is an increase in CI.

  13. Caso 4/2003 - Paciente de 61 anos, portadora de cardiopatia da doença de Chagas, com disfunção ventricular, taquicardia ventricular recorrente e marcapasso cardíaco, que apresentou morte em assistolia após ressecção cirúrgica de aneurisma de ponta

    Franco Fábio Gazelato

    2003-01-01

    Full Text Available A 61 year-old Chagasic woman, with previous left ventricular systolic disfunction, ventricular tachychardia and cardiac pacemaker, presented cardiac arrest in asystolia after surgical ressection of apical aneurysm.

  14. Development of Nb{sub 2}O{sub 5}|Cu composite as AISI 1020 steel thermal spray coating for protection against corrosion by soil in buried structures; Desenvolvimento e uso do composito de Nb{sub 2}O{sub 5}|Cu como revestimento aplicado por aspersao termica sobre o aco AISI 1020 para protecao contra a corrosao pelo solo em estruturas enterradas

    Regis Junior, Oscar [Universidade Tecnologica Federal do Parana, Ponta Grossa, PR (Brazil). Dept. de Mecanica; Silva, Jose Maurilio da; Portella, Kleber Franke [Instituto de Tecnologia para o Desenvolvimento, Curitiba, PR (Brazil). Dept. de Pesquisa em Engenharia Civil; Paredes, Ramon Sigifredo Cortes, E-mail: regis@utfpr.edu.br [Universidade Federal do Parana, Curitiba, PR (Brazil). Dept. de Mecanica

    2012-07-01

    An Nb{sub 2}O|Cu corrosion-resistant coating was developed and applied onto AISI 1020 steel substrate by Powder Flame Spray. A galvanostatic electrochemical technique was employed, with and without ohmic drop, in four different soils (two corrosively aggressive and two less aggressive). Behavior of coatings in different soils was compared using a cathodic hydrogen reduction reaction (equilibrium potential, overvoltage and exchange current density) focusing on the effect of ohmic drop. Results allow recommendation of Nb{sub 2}O{sub 5}|Cu composite for use in buried structure protection. (author)

  15. Cytomegalovirus and other herpesviruses infections in heart and bone marrow transplant recipients Infecções causadas por citomegalovírus e outros vírus do grupo herpes em transplantados cardíacos e de medula óssea

    Adriana Weinberg; Lucy S. Vilas Boas; Olavo Feher; Tania M. V. Strabelli; Maria Cristina D. S. Fink; Frederico L. Dulley; Uip, David E.; Giovani Bellotti; Dalton A. F. Chamone; Vicente Amato Neto; Pannuti, Cláudio S.

    1990-01-01

    From January 1988 to January 1989 all the heart transplant and bone marrow recipients at the Instituto do Coração of the Hospital das Clínicas of the University of São Paulo Medical School were studied for the incidence and morbidity associated with herpesviruses infections after transplantation. Five bone marrow and 5 heart transplant recipients were followed for a mean of 4.2 months post-transplantation. All the patients were seropositive for cytomegalovirus (CMV) before admission and 80% e...

  16. Quantificação de tecido conjuntivo do músculo cardíaco em equinos de tração através de técnicas histoquímicas e morfométricas Quantification of connective tissue in cardiac muscle from horses used for traction using histochemical and morphometric techniques

    Eduardo Maurício Mendes de Lima; Marcelo Ismar Silva Santana; Márcio Botelho de Castro; Pedro Primo Bombonato; Hildebrando Gomes Benedicto; André Rodrigues da Cunha Barreto Vianna

    2011-01-01

    Os cardiomiócitos são sustentados e inseridos em um esqueleto de tecido conjuntivo, este possui distribuição desigual de acordo com as propriedades das distintas regiões em que se encontra. O propósito deste estudo foi quantificar a proporção de tecido conjuntivo em relação à disposição de cardiomiócitos dos ventrículos direito e esquerdo e no septo interventricular do miocárdio de seis equinos subnutridos, adultos, sendo quatro machos e duas fêmeas, sem raça definida e utilizados para tração...

  17. Desarrollo de producto sobre la base de harinas de cereales y leguminosa para niños celíacos entre 6 y 24 meses; I: Formulación y aceptabilidad Product development on the basis of cereal and leguminous flours to coeliac disease in children between 6-24 months; I: formulation and acceptability

    P. Cerezal Mezquita

    2011-02-01

    Full Text Available La revalorización de los cultivos andinos, quinua (Chenopodium quinua Willd y lupino (Lupinus albus L, para ser utilizados en mezclas alimenticias, con cereales tradicionales como maíz (Zea mays L. y arroz (Oryza sativa L., originan mezclas sin gluten que constituyen una buena alternativa para la alimentación de niños menores de 24 meses que sufren la enfermedad celíaca, ya que mejoran la calidad de la proteína, por compensación de los aminoácidos esenciales, e incide en la diversificación de productos. En el presente trabajo se determinó la composición de los porcentajes de cada harina en la mezcla mediante Programación Lineal empleando la planilla Solver de la hoja de cálculo Excel. Se determinaron las prolaminas en las harinas de quinua y lupino por el método ELISA y se empleó la técnica del HPLC en los dos productos obtenidos, denominados "mezcla dulce" y "mezcla postre", para definir la cantidad de aminoácidos con la finalidad de suplementar alrededor del 15% de las proteínas requeridas en el día. Las mezclas de harina seleccionadas como óptimas, mezcla dulce, apropiada para la preparación de queques, así como para la mezcla postre, que por adición de agua o leche, da origen a un postre, se evaluaron después de tres meses de almacenamiento, siendo aceptables sus requisitos microbiológicos, bromatológicos y sensoriales, corroborándose los resultados, con la buena aceptación de los productos preparados a partir de las mezclas formuladas, por parte de los menores de 2 Jardines Infantiles de la Ciudad de Antofagasta-Chile.The revaluation of the Andean cultivations, quinua (Chenopodium quinua Willd and lupin (Lupinus albus L., to be used in nutritional mixtures, with traditional cereals like corn (Zea mays L. and rice (Oryza sativa L., originate mixtures without gluten which constitute a good alternative for the nutrition of children under 24 months that suffer from celiac disease, since they improve the quality of the protein, by essential amino acids compensation, and also impacts in the product's diversification strategy. In the present work, the percentage composition of each flour in the mixture was determined by means of Linear Programming by means of the Solver form from the Excel spreadsheet. Prolamines were determined in the quinua and lupin flours by the ELISA test and the HPLC technique was used in both products obtained called "sweet mix" and "dessert mix", to define the quantity of amino acids with the purpose of providing around the 15% of the proteins required in the day. The flour mixtures selected as optimum, sweet mix, suitable for the preparation of sweet pancakes, as well as for the dessert mix, that by addition of water or milk produce a semi solid dessert, were evaluated after three months of storage, being acceptable their microbiological, bromatological and sensorial requirements, corroborating the results with the good acceptance of the products, prepared from the formulated mixtures, by the children of two Day Care centers of the City of Antofagasta-Chile.

  18. Desarrollo de producto sobre la base de harinas de cereales y leguminosa para niños celíacos entre 6 y 24 meses; I: Formulación y aceptabilidad Product development on the basis of cereal and leguminous flours to coeliac disease in children between 6-24 months; I: formulation and acceptability

    P. Cerezal Mezquita; V. Urtuvia Gatica; V. Ramírez Quintanilla; N. Romero Palacios; R. Arcos Zavala

    2011-01-01

    La revalorización de los cultivos andinos, quinua (Chenopodium quinua Willd) y lupino (Lupinus albus L), para ser utilizados en mezclas alimenticias, con cereales tradicionales como maíz (Zea mays L.) y arroz (Oryza sativa L.), originan mezclas sin gluten que constituyen una buena alternativa para la alimentación de niños menores de 24 meses que sufren la enfermedad celíaca, ya que mejoran la calidad de la proteína, por compensación de los aminoácidos esenciales, e incide en la diversificació...

  19. Efeitos da acupuntura nos acupontos Shenmen (C-7 e Neiguan (PC-6 sobre a frequência cardíaca, a variabilidade da frequência cardíaca e o ritmo cardíaco em cães saudáveis

    E.G.M. Silva

    2016-02-01

    Full Text Available Acupuncture derives from traditional Chinese medicine, which aims to restore homeostasis. The action mechanism of this technique involves stimulation of certain points on the skin by inserting a needle. The aim of this study was to evaluate the influence of stimulation of acupoints C7 and PC6 on the heart rate variability, heart rate and heart rhythm in healthy dogs. 30 male and female adult dogs were used, with no breed restriction. The animals were analyzed at two different times in weekly intervals. Firstly were applied needles in the true acupoints, and on the second time we applied needles in false acupoints. Previously to the acupuncture an ECG with 2 minutes of recorder was performed, and after an insertion of needles the electrocardiographic recording was maintained during the 30 minutes of acupuncture. Results showed no significant difference between the HR when comparing true and false acupoints (p = 0.890. For heart rate variability a small difference was observed between the groups (p = 0.0051, however, when comparing the baseline with 15 and 25 minutes of monitoring in the false acupoint group, no significant results were found when compared with true acupoint. In conclusion, it is suggested that the stimulation of acupoints C-7 and PC-6 in healthy dogs does not promote change in sympathovagal balance, specifically on the heart rate variability, heart rate and heart rhythm on healthy dogs.

  20. Inflamação sistêmica causada pela periodontite crônica em pacientes vítimas de ataque cardíaco isquêmico agudo Systemic inflammation caused by chronic periodontitis in acute ischemic heart attack patients

    Fernando José de Oliveira

    2010-03-01

    Full Text Available OBJETIVO: Processos inflamatórios e infecciosos mediados por bactérias em sítios distantes têm sido descritos como fator de risco à doença coronariana isquêmica aguda (DCIA. MÉTODOS: Cento e oitenta e um pacientes com DCIA, com e sem periodontites crônicas, foram incluídos neste estudo. Os pacientes foram admitidos no HC da UNICAMP e estratificados em três grupos: grupo 1 - pacientes com periodontite crônica grave (31 homens e 19 mulheres; média de idade 55,1 ± 11,29 anos; grupo 2 - pacientes com periodontite crônica leve (40 homens e 28 mulheres; média de idade 54,8 ± 10,37 anos; grupo 3 - pacientes desdentados (43 homens e 20 mulheres; média de idade 67,5 ± 8,55 anos. Amostras sanguíneas foram coletadas para mensurar os perfis lipídico, hematológico e glicêmico. Além disso, biópsias de 17 artérias coronárias com aterosclerose e igual número de artérias mamárias internas sem degeneração aterosclerótica no grupo 1 foram investigadas. Para análise estatística utilizou-se a análise de variância (ANOVA e o teste de Scheffé para comparações múltiplas. RESULTADOS: Triglicérides e LDL estavam elevados no grupo 1 em relação ao grupo 2. O HDL apresentou-se reduzido em 20% dos pacientes do grupo 1, e em 8% nos desdentados. A glicemia estava elevada no grupo 1. DNA de bactérias periodontais foram detectados em 58,8% das artérias coronárias. CONCLUSÕES: Pacientes com DCIA e periodontite crônica grave podem apresentar perfil lipídico alterado, como também microorganismos associados com as periodontites crônicas graves podem permear dentro de vasos coronarianos.OBJECTIVE: Infectious and inflammatory processes mediated by bacteria in distant sites have been described as a risk factor for acute ischemic heart disease (AIHD. METHODS: One hundred one patients with AIHD with and without chronic periodontitis (CP were included in this study. Patients were admitted to the HC UNICAMP and stratified into three groups: in group 1, we selected patients with severe chronic periodontitis (31 men and 19 women, mean age 55.1 ± 11.29 years old; the group 2 with mild chronic periodontitis (40 men and 28 women, mean age 54.8 ± 10.37 years old and group 3 represented by the toothless (43 men and 20 women, mean age 67.5 ± 8.55 years old. Blood samples were collected to measure the lipid profiles, hematological and blood glucose levels. In addition, biopsies of seventeen coronary arteries with atherosclerosis and an equal number of internal mammary arteries without atherosclerotic degeneration in group 1 were investigated. Statistical analysis by analysis of variance (ANOVA and Scheffé test for multiple comparisons was performed. RESULTS: Triglyceride and LDL levels were elevated in group 1 than in group 2. HDL were reduced by 20% in group 1 and remained reduced by 8% in toothless. Blood glucose was higher in group 1. DNA of periodontal bacteria was detected in 58.8% of the coronary arteries. CONCLUSIONS: Patients with (AIHD and severe chronic periodontitis may have altered lipid profile, as well as microorganisms associated with CP can permeate into coronary vessels.

  1. Drenagem anômala de veia pulmonar inferior direita em veia cava inferior associada a apêndice hepático intracardíaco Anomalous drainage of the right inferior pulmonary vein into the inferior vena cava associated to intrathoracic hepatic appendix

    Carlos R Moraes

    1988-08-01

    Full Text Available Descreve-se o caso de uma paciente de 61 anos de idade, com drenagem anômala de veia pulmonar inferior direita em veia cava inferior, associada a apêndice hepático intratorácico, herniado através de fenda no diafragma. A correção cirúrgica foi realizada por anastomose direta da veia anômala com o átrio esquerdo, pela redução do apêndice hepático para a cavidade abdominal e, finalmente, pelo fechamento do defeito diafragmático. O pós-operatório decorreu sem qualquer complicação. Os autores chamam a atenção para a raridade do caso.The authors present a case of a 61-year-old woman with anomalous drainage of the right inferior pulmonary vein into the inferior vena cava associated to an intrathoracic hepatic appendix herniated through a diaphragmatic defect. Surgical correction was obtained by direct anastomosis of the anomalous vein to the left atrium, reduction of the hepatic appendix to the abdominal cavity and closure of the diphragmatic defect. The postoperative course was unevenftul. The rarity of this condition is stressed.

  2. Actions to ensure the power and utilities supplying during the start-up and regular operation of the TKCSA steel complex through island operation mode; Acoes para garantir o suprimento de energia eletrica e utilidades durante a fase de start up e de operacao regular do complexo siderurgico da TKCSA (Thyssenkrupp - Companhia Siderurgica do Atlantico) atraves do modo de operacao em ilha

    Vianna, Bernardo Matoso T.; Viana, Claudio Sobreira; Vaz, Daniel; Cesario, Fabricio; Pereira, Jose Antonio; Gimenez, Marcus Vinicius O.; Pascotto, Ricardo; Freitas Neto, Roberto Soares; Riederer, Werner [ThyssenKrupp Companhia Siderurgica do Atlantico (TKCSA), Rio de Janeiro, RJ (Brazil)

    2011-12-21

    At TKCSA, the energy and media distribution has an important function in the production processes. The electrical department is responsible for the power system operation, ensuring the receiving, transformation and supplying of this media for the regular and stable operation of the electrical equipment of the steel processes, and another important assignment of the electrical power sector is to guarantee the continuous power supply for the complex, even in case of interruption caused by the external grid, since the blast furnace, steel making and continuous casting cannot be interrupted abruptly. This continuous supply of energy is guaranteed by the Island Operation Mode (IOM), which always aims to ensure the supply of electricity from the Power Plant for the blowers, technical gases distribution system, fuel gases, steam and internal distribution of electricity and industrial water for the steel mill complex. During the complex start up and the regular operation phases, these two distribution systems (electricity and media) work interconnected and are kept in operation by the IOM, being guaranteed by the permanent operation of the electrical power generation system of Power Plant. This work presents how this concept was developed, tested and implemented at TKCSA. (author)

  3. Inflamação sistêmica causada pela periodontite crônica em pacientes vítimas de ataque cardíaco isquêmico agudo Systemic inflammation caused by chronic periodontitis in acute ischemic heart attack patients

    Fernando José de Oliveira; Reinaldo Wilson Vieira; Otávio Rizzi Coelho; Orlando Petrucci; Pedro Paulo Martins de Oliveira; Nilson Antunes; Ivone Pires F. de Oliveira; Edson Antunes

    2010-01-01

    OBJETIVO: Processos inflamatórios e infecciosos mediados por bactérias em sítios distantes têm sido descritos como fator de risco à doença coronariana isquêmica aguda (DCIA). MÉTODOS: Cento e oitenta e um pacientes com DCIA, com e sem periodontites crônicas, foram incluídos neste estudo. Os pacientes foram admitidos no HC da UNICAMP e estratificados em três grupos: grupo 1 - pacientes com periodontite crônica grave (31 homens e 19 mulheres; média de idade 55,1 ± 11,29 anos); grupo 2 - pacient...

  4. Caracterização da relação entre a massa muscular esquelética e aptidão física funcional de pessoas com insuficiência cardíaca crónica após implante cardíaco de ressincronização.

    Santos, Vanessa Sofia Teigão dos

    2015-01-01

    Mestrado em Exercício e Saúde Contexto: A terapia de ressincronização cardíaca (TRC) é recomendada para reduzir a mortalidade e morbilidade em doentes com insuficiência cardíaca crónica (ICC), cujos sintomas permanecem na classe II-IV da New York Heart Association (NYHA). Objetivo: O objetivo do estudo foi caracterizar a composição corporal e a aptidão física funcional destes doentes com TRC e verificar associações. Métodos: O estudo foi transversal observacional e descritivo, com um...

  5. Avaliação da segurança do teste de caminhada dos 6 minutos em pacientes no pré-transplante cardíaco Evaluación de la seguridad de la test de marcha de 6 minutos en pacientes en el pre-transplante cardiaco Analysis of 6-minute walk test safety in pre-heart transplantation patients

    Gerson Cipriano Jr

    2009-04-01

    Full Text Available FUNDAMENTO: O teste de caminhada dos 6 minutos (TC6 tem sido utilizado como forma de avaliação da capacidade funcional, estadiamento clínico e prognóstico cardiovascular. A segurança e o impacto metabólico são pouco descritos na literatura, principalmente em pacientes com insuficiência cardíaca grave, com indicação clínica para transplante cardiovascular. OBJETIVO: Avaliar a ocorrência de arritmias e alterações cardiovasculares durante o TC6. Correlacionar o desempenho no TC6 com o estadiamento clínico e prognóstico cardiovascular. MÉTODOS: Doze pacientes, sendo 10 masculinos, com idade de 52 ± 8 anos, foram submetidos à avaliação inicial. Realizaram o TC6 com monitoramento eletrocardiográfico por telemetria, sinais vitais e lactato. Foram acompanhados por 12 meses. RESULTADOS: Os pacientes percorreram 399,4 ± 122,5 (D, m, atingindo um esforço percebido (EP de 14,3 ± 1,5 e variação de 34% na freqüência cardíaca basal. Dois pacientes apresentaram arritmia de maior gravidade pré-TC6 e não pioraram ante o esforço, quatro tiveram elevação significativa nos níveis de lactato sangüíneo (>5 mmol/dl, e três interromperam o exame. A distância percorrida evidenciou correlação com a fração de ejeção (% e classificação funcional (NYHA. Após 12 meses de seguimento, três pacientes foram a óbito, e reinternaram-se sete por descompensação cardíaca. A relação (D/EP e freqüência cardíaca de recuperação no segundo minuto (FCR2, bpm foram inferiores no grupo-óbito. CONCLUSÃO: O comportamento clínico e eletrocardiográfico sugere que o método é seguro, mas pode ser considerado de alta intensidade para alguns pacientes com insuficiência cardíaca grave. Variáveis relacionadas ao desempenho no TC6 podem estar associadas com a mortalidade no seguimento de um ano.FUNDAMENTO: El test de marcha de 6 minutos (TM6m ha sido utilizado como forma de evaluación de la capacidad funcional, del estadiamiento clínico y el pronóstico cardiovascular. La seguridad y el impacto metabólico son poco descritos en la literatura, principalmente en pacientes con insuficiencia cardiaca severa e indicación clínica para transplante cardiovascular Objetivo: Evaluar la ocurrencia de arritmias y alteraciones cardiovasculares durante el TM6m. Correlacionar el desempeño en el TM6m con el estadiamiento clínico y el pronóstico cardiovascular. MÉTODOS: Un total de 12 pacientes, 10 varones, con edad de 52 ± 8 años, fueron sometidos a evaluación inicial. Realizaron el TM6m con monitoreo electrocardiográfico por telemetría, señales vitales y lactato. Se siguieron a los individuos por 12 meses. RESULTADOS: Los pacientes recorrieron 399,4 ± 122,5 (D, m, alcanzando un esfuerzo percibido (EP de 14,3 ± 1,5 y variación del 34% en la frecuencia cardiaca basal. Dos pacientes presentaron arritmia de mayor severidad pre-TM6m y no mostraron empeoramiento ante el esfuerzo; cuatro tuvieron elevación significativa en los niveles de lactato sanguíneo (>5 mmol/dl, y tres interrumpieron el examen. La distancia recorrida evidenció correlación con la fracción de eyección (% y la clasificación funcional (NYHA. Tras 12 meses de seguimiento, tres pacientes murieron, y siete se reinternaron por descompensación cardiaca. La relación (D/EP y frecuencia cardiaca de recuperación en el segundo minuto (FCR2, lpm fueron inferiores en el grupo óbito. CONCLUSIÓN: El comportamiento clínico y electrocardiográfico sugiere que el método es seguro, pero se puede considerarlo de alta intensidad para algunos pacientes con insuficiencia cardiaca severa. Variables relacionadas al desempeño en el TM6m pueden estar asociadas con la mortalidad en el seguimiento de un año.BACKGROUND: The 6-minute walk test (6WT has been used as a means of assessment of the functional capacity, clinical staging and cardiovascular prognosis. Its safety and metabolic impact have not been frequently described in the literature, especially in patients with severe heart failure with clinical indication for cardiovascular transplantation. OBJECTIVE: To evaluate the occurrence of arrhythmias and cardiovascular changes during 6WT. To correlate 6WT performance with clinical staging and cardiovascular prognosis. METHODS: Twelve patients, 10 of whom males, aged 52 ± 8 years were evaluated at baseline. 6WT was performed with telemetry electrocardiography, vital signs and lactate monitoring. The patients were followed-up for 12 months. RESULTS: The patients walked 399.4±122.5 (D, m, reaching a perceived exertion (PE of 14.3±1.5 and a 34% baseline heart rate variation. Two patients presented more severe pre-6WT arrhythmia which did not worsen with the exercice, four patients presented a significant increase of blood lactate levels (>5 mmol/dl, and three interrupted the test. The distance walked correlated with the ejection fraction (% and functional class (NYHA. After 12-month follow-up, three patients died and seven were rehospitalized for cardiac decompensation. The D/PE ratio and 2-minute heart rate recovery (HRR2, bpm were lower in the death group. CONCLUSION: The clinical and electrocardiographic behaviors suggest that the method is safe, but it may be considered too strenuous for some patients with severe heart failure. Variables related to 6WT performance may be associated with the one-year follow-up mortality.

  6. Tratamento convencional e endovascular para rara associação de doenças: síndrome de veia cava superior e aneurisma aorto-ilíaco - controle após 12 meses Conventional and endovascular treatment for a rare combination of diseases: superior vena cava syndrome and aortoiliac aneurysm - control after 12 months

    Gustavo Petorossi Solano

    2011-09-01

    Full Text Available A associação entre a síndrome de veia cava superior e uma dilatação aneurismática das artérias aorta e ilíacas não é comum. A abordagem de cada uma destas patologias pode ser efetuada através do modo convencional, com cirurgia aberta ou pela técnica endovascular. Neste trabalho, relatamos as duas modalidades de intervenção cirúrgica executadas e discutimos suas indicações e os resultados deste caso em particular.The association between superior vena cava syndrome and an aorto-iliac aneurysm is not common. The approach to each of theses diseases can be either by the conventional way with open surgery or by endovascular techniques. We report the two methods of surgical intervention and discuss their indications and results in this particular case.

  7. Environmental education at Bacia de Campos: activities sponsored by the Exploration and Production business Unit in the state of Rio de Janeiro, Brazil; Educacao ambiental na Bacia de Campos: acoes desenvolvidas na Unidade de Negocios de Exploracao e Producao do Rio de Janeiro

    Freire, Ana Lucia Bueno; Vidal, Roseane Dias de Medeiros; Rocha, Valmir Gomes da [PETROBRAS, Rio de Janeiro, RJ (Brazil). Unidade de Negocios

    2004-07-01

    PETROBRAS Exploration and Production Business Unit in the State of Rio de Janeiro - PETROBRAS/UN-RIO has been developing environmental education actions as part of its environmental license process at Campos Basin. These actions are included in the project for the education of the multiplier groups in environmental education and core skills on environmental education. The goals of the project are either to create an integrated understanding of the environmental issue and a responsible conduction on natural resource and community values preservation. The multiplier groups are formed by associated professionals from the state government secretaries of education, health, environment and infra-structure areas. This Project has been developed at the north area of the State of Rio de Janeiro since 1999, in partnership of the Non Government Organization - NGO named 'Centro Norte Fluminense para Conservacao da Natureza - CNFCN'. Initial actions were based on a training course to prepare multiplier professionals on environmental education. In order to keep the multiplier Professional updated on environmental skills additional training course and local seminars are planned to be implemented in the region. Another project consider to create environmental skill cores to be implemented in the region based on training courses through either the use of the local public schools facilities and the volunteer contribution of the multiplier professionals. (author)

  8. Sistema inalámbrico de monitorización cardíaco : integración con dispositivos móviles inteligentes mediante el diseño de una aplicación en la capa Software as a Service (SaaS) en el entorno de Google Cloud

    Sáez Sánchez, Sergio

    2015-01-01

    El presente proyecto final de grado está enfocado al estudio de las posibilidades de almacenamiento y procesamiento que se pueden encontrar hoy en día en la nube, así como su relación con las aplicaciones móviles para smarthpones, más concretamente en el ámbito de la salud. Para poder cumplir el objetivo mencionado, se realizará el estudio de un caso práctico de una toma de datos de un sensor de frecuencia cardiaca, y se le aplicarán una serie de algoritmos para poder tener tod...

  9. Desarrollo de producto sobre la base de harinas de cereales y leguminosa para niños celíacos entre 6 y 24 meses; II: Propiedades de las mezclas Product development on the basis of cereal and leguminous flours to coeliac disease in children aged 6-24 months; II: properties of the mixtures

    P. Cerezal Mezquita; V. Urtuvia Gatica; V. Ramírez Quintanilla; R. Arcos Zavala

    2011-01-01

    Las formulaciones alimenticias de alto contenido proteico, aportado por una mezcla de harinas a partir de dos cultivos andinos, quinua (Chenopodium quinua Willd) y lupino (Lupi-nus albus L), con dos cereales tradicionales maíz (Zea mays L.) y arroz (Oryza sativa L.), conllevaron a la preparación de una 'mezcla dulce' para la elaboración de queques y otra "mezcla postre" saborizada con plátano, que puede ser preparada con agua o con leche, constituyeron una buena alternativa como suplemento al...

  10. Exercício de força ativa a via AKT/mTor pelo receptor de angiotensina II tipo I no músculo cardíaco de ratos Activation of AKT-mTor signaling pathways by angiotensin II receptor type 1 after a session of strength exercise in cardiac muscle of rats

    Stéphano Freitas Soares Melo

    2011-09-01

    Full Text Available O receptor de angiotensina II tipo I (AT1 tem uma importante participação no desenvolvimento da hipertrofia cardíaca. Em um trabalho publicado anteriormente, por nosso grupo, demonstramos que o bloqueio do receptor AT1 durante o treinamento de força inibiu a hipertrofia cardíaca em ratos. Por isso, o objetivo deste trabalho foi estudar a participação do receptor AT1 na ativação de vias de sinalização intracelular relacionadas com o aumento da síntese de proteína em ratos submetidos a uma sessão de exercício de força. Para isso, realizamos um experimento com seis grupos de animais (n = 6; cada: controle (Con, exercitado e sacrificado cinco minutos após o exercício (Exe 5, exercitado e sacrificado 30 minutos após o exercício (Exe 30, controle tratado com losartan (Con Los, tratado com losartan, exercitado e sacrificado cinco minutos após o exercício (Exe 5 Los, tratado com losartan, exercitado e sacrificado 30 minutos após o exercício (Exe 30 Los. Os resultados mostram que no grupo Exe 5 e Exe 30 ocorreu um aumento de 63% (P The angiotensin II type I (AT1 receptor has an important participation in the development of cardiac hypertrophy. Previously, we have shown that AT1 receptor participates in the cardiac hypertrophy induced by resistance training in rats. Here, we studied the involvement of AT1 receptor in the activation of intracellular signaling pathways related to the concentric HC in rats submitted to a session of strength exercise. Male Wistar rats were divided into 6 groups (n= 6 each: control (Con; exercised and killed 5 minutes after exercise (Exe 5; exercised and killed 30 minutes after exercise (Exe 30; control treated with Losartan (Con Los; treated with Losartan, exercised and killed 5 minutes after the exercise (Exe Los 5; treated with Losartan, exercised and killed 30 minutes after training (Exe Los 30. The results show that phosphorylation activity of AKT in group Exe 5 and Exe 30 increased 63% (P < 0.05 and 62% (P < 0.05, respectively, compared with Con. Whereas the phosphorylation of mTOR was increased 65% (P < 0.05, compared to Con, only in the group Exe 30. Furthermore, these effects were blocked by losartan treatment in groups Exe Los 5 and Exe Los 30. These results, together with ours previous data shows that the AT1 receptor has an role in the activation of AKT and mTOR pathway after a session of strength exercise.

  11. Visceral leishmaniasis in heart transplant patients in the endemic state of Ceará, Brazil: a report of two casesLeishmaniose visceral em pacientes submetidos a transplante cardíaco no estado do Ceará, área endêmica no Brasil: um relato de dois casos

    Bráulio Matias de Carvalho

    2016-03-01

    Full Text Available Visceral leishmaniasis (VL in transplant patients is a serious disease, with atypical and aggressive manifestations, compromising patient survival. During the period from 2008 to 2012, 126 heart transplants were performed in the state of Ceará, Brazil, of which, two patients developed VL. Fever, pancytopenia and hepatosplenomegaly were the common clinical signs. Both patients were diagnosed and properly treated, but the first one had a clinical relapse and died, five months after treatment. These findings emphasize the importance of investigating VL in heart-transplant patients in endemic areas and highlight the importance of early diagnosis and treatment for favorable clinical outcomes.

  12. The use of steel and lead shieldings in radiotherapy rooms and its comparison with respect to neutrons doses at patients; Comparacao de blindagens de aco e de chumbo usadas em salas de radioterapia quanto a dose devido a neutrons depositada em pacientes

    Silva, M.G.; Rebello, W.F.; Andrade, E.R.; Medeiros, M.P.C.; Mendes, R.M.S.; Braga, K.L.; Gomes, R.G., E-mail: maglosilva15@gmail.com, E-mail: rebello@ime.eb.br, E-mail: fisica.dna@gmail.com, E-mail: eng.cavaliere@gmail.com, E-mail: raphaelmsm@gmail.com, E-mail: kelmo.lins@gmail.com, E-mail: ggrprojetos@gmail.com [Instituto Militar de Engenharia (IME), Rio de Janeiro, RJ (Brazil); Santos, R.F.G., E-mail: raphaelfgsantos@gmail.com [Centro Universitario Anhanguera, Niteroi, RJ (Brazil). Departamento de Engenharia; Silva, Ademir X., E-mail: ademir@con.ufrj.br [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil)

    2015-07-01

    The NCRP Report No. 151, Structural Shielding Design and Evaluation for Megavoltage X- and Gamma-Ray Radiotherapy Facilities, considers, in shielding calculations for radiotherapy rooms, the use of lead and/or steel to be applied on bunker walls. The NCRP Report calculations were performed foreseeing a better protection of people outside the radiotherapy room. However, contribution of lead and steel to patient dose should be taken into account for radioprotection purposes. This work presents calculations performed by MCNPX code in analyzing the Ambient Dose Equivalent due to neutron, H*(10){sub n}, within a radiotherapy room, in the patients area, considering the use of additional shielding of 1 TVL of lead or 1 TVL of steel, positioned at the inner faces of walls and ceiling of a bunker. The head of the linear accelerator Varian 2100/2300 C/D was modeled working at 18MeV, with 5x5cm{sup 2}, 10x10cm{sup 2}, 20x20cm{sup 2}, 30x30cm{sup 2} and 40x40cm{sup 2} openings for jaws and MLC and operating in eight gantry's angles. This study shows that the use of lead generates an average value of H*(10){sub n} at patients area, 8.02% higher than the expected when using steel. Further studies should be performed based on experimental data for comparison with those from MCNPX simulation.

  13. Characterization of the corrosion behavior of an austenitic stainless steel for biomedical applications coated with Ti N, Ti CN And DLC PVD coatings; Caracterizacao do comportamento frente a corrosao de um aco inoxidavel austenitico para aplicacoes biomedicas com revestimentos PVD de TiN, TiCN e DLC

    Antunes, Renato Altobelli

    2006-07-01

    Metallic biomaterials must present a combination of properties such as corrosion resistance, biocompatibility and mechanical resistance. Austenitic stainless steels, especially AISI 316L combine these properties with the easy of fabrication at low cost. However, they are prone to corrosion in physiological solutions. Furthermore, their corrosion products may lead to infectious ou allergenic reactions in the tissues around the implant device. In the present work, coatings produced by physical vapour deposition (PVD) methods have been applied on the surface of a 316L stainless steel to increase its corrosion resistance and biocompatibility. Three thin films were tested: titanium nitride (TiN), titanium carbonitride (TiCN) and diamond-like carbon (DLC). These materials present high hardness, wear resistance and intrinsic biocompatibility that are key features when considering biomedical applications. The characterization of the electrochemical behavior of the stainless steel coated with the three different films showed that the presence of surface defects are deleterious to the corrosion resistance of the substrate. These defects were observed using scanning electron microscopy. The evolution of the electrochemical behavior of the coated steel was explained through a mechanism based on the experimental results obtained using electrochemical impedance spectroscopy. Two different passivation treatments were carried out on the stainless steel surface, either in sulfuric or nitric acid solutions, to increase its corrosion resistance. The results suggested que these treatments were not efficient, but may be modified to improve its performance. The electronic properties of the passive films of the non-passivated and passivated stainless steel were studied using the Mott-Schottky approach. The films presented a duplex character. Below the flat band potential the behavior is typical of a highly doped type-p semiconductor. Above the flat band potential is typical of a highly doped type-n semiconductor. The doping concentration in the passive film was determined and associated with the corrosion resistance of the substrate. All PVD coatings investigated showed non-cytotoxic behavior. DLC and TiCN coatings decreased the friction coefficient of the stainless steel substrate. These properties allied with the stainless steel low cost recommend their commercial use for implants materials purposes. Nevertheless the corrosion resistance presented by the coated-steel was inferior to that of the bare steel and should be improved. At the end of the present text, some suggestions are proposed in order to improve the corrosion protection performance of the PVD coatings.

  14. Texture development study during the primary recrystallization of ferritic steels by using X ray and electron backscattering diffraction; Estudo do desenvolvimento da textura durante a recristalizacao primaria de acos ferriticos por difracao de raio-X e difracao de eletrons retroespalhados

    Loew, Marjorie

    2006-07-01

    X ray and electron backscattering diffraction, in distinct levels, were applied to evaluate microstructural changes in two low carbon ferritic steels (2 per cent Si and ABNT 1006), observing the texture development in cold lamination step (skin-pass) and in the subsequent annealing at 760 deg C. In these two steels, results showed that after the skin-pass and annealing in the conditions of the present work, the observed phenomenon is the primary recrystallization. By applying skin-pass dislocations were introduced mostly in low Taylor factor grains as they are prone to be more deformed. Nucleation and grain growth were observed in high density dislocation cell regions. Silicon presence delayed the recovery favoring the sub-boundaries increase. It was not observed the abnormal grain growth, even in the presence of Gross grains. CSL boundaries did not guarantee the grains growth. Growing nuclei gave rise to grains with distinct orientations, showing that the grain growth was not dependent on the previous presence of grains with the developed orientation. This fact demonstrates that the abnormal grain growth is not necessarily related to the Gross grains. (author)

  15. Evaluation of the mitochondrial respiration of cardiac myocytes in rats submitted to mechanical bile duct obstruction Avaliação da respiração mitocondrial de miócitos cardíacos em ratos ictéricos sumetidos à obstrução do ducto biliar

    Rafael Kemp; Orlando de Castro-e-Silva; José Sebastião dos Santos; Ajith Kumar Sankarankutty; Rodrigo Borges Correa; Caroline Floreoto Baldo; Maria Elisa Jordani Souza; Maria Cecilia Jordani

    2008-01-01

    PURPOSE: The objective of the present study was to evaluate the capacity of the myocardium for energy production by the analysis of mitochondrial respiration in rats with jaundice submitted to bile duct ligature. METHODS: Sixteen male Wistar rats were divided into 2 Groups: Group SO submitted to nontherapeutic laparotomy (sham operation) and Group IC (icteric group) submitted to bile duct ligature. After 7 days, laparotomy was again performed in all animals for cardiac muscle extraction and a...

  16. Inibição da corrente de cálcio tipo L por tramadol e enantiômeros em miócitos cardíacos de ratos Inhibition of L-type calcium current by tramadol and enantiomers in cardiac myocytes from rats

    Emiliano Medei; Juliana M. Raimundo; José Hamilton M. Nascimento; Margarete M. Trachez; Roberto T. Sudo; Gisele Zapata-Sudo

    2011-01-01

    FUNDAMENTO: O tramadol é um analgésico de ação central cujo mecanismo de ação envolve a ativação de um receptor opioide. Anteriormente, mostramos que o tramadol e seus enantiômeros apresentavam um efeito inotrópico negativo sobre o músculo papilar no qual o (+)-enantiômero era mais potente que (-)- e (±)-tramadol. OBJETIVO: No presente trabalho, investigamos os efeitos do tramadol e seus enantiômeros na corrente de cálcio tipo L (I Ca-L). MÉTODOS: Os experimentos foram realizados em miócitos ...

  17. Desarrollo de una escala de auto reporte para medición de síntomas maníacos basado en la escala de manía de la Universidad Nacional de Colombia (EMUN) / Development of a scale of selfreport for measurement ofmaniacal symptoms based on the scale of mania of the National University of Colombia (EMUN)

    Barrios Martínez, Karol Juliana

    2011-01-01

    Objetivo: Disponer de un instrumento en formato de auto-reporte basada en la escala EMUN, que optimice la evaluación clínica y que facilite el desarrollo de la investigación a nivel de síndrome maniaco en pacientes colombianos con trastorno afectivo bipolar. Diseño: adaptación y desarrollo de un cuestionario Escenario: servicios de urgencias, Hospital la victoria, Clínica nuestra señora de la paz. Población: 20 pacientes que aceptaron participar en el estudio con diagnostico de t...

  18. Comparative study of the impacts of hydroelectric power plants with impacts avoided by a Virtual Plants Equivalents (VPEs) through of energy efficiency actions; Estudo comparativo dos impactos das usinas hidreletricas com os impactos evitados por uma usina virtual equivalente atraves das acoes de eficiencia energetica

    Silva, Roberto Perillo Barbosa da; Barros, Regiane Silva de [Universidade Estadual de Campinas (FEM/UNICAMP), SP (Brazil). Fac. de Engenharia Mecanica], emails: rpbsilva@fem.unicamp.br, rsbarros@fem.unicamp.br Rossi, Luiz Antonio [Universidade Estadual de Campinas (FEAGRI/UNICAMP), SP (Brazil). Fac. Engenharia Agricola], email: rossi@feagri.unicamp.br

    2010-07-01

    This article presents a comparative study of the impacts caused by Hydroelectric Power Plants (HPPs) in relation to the impacts avoided through actions that promotes energy efficiency called Virtual Plants Equivalents (VPEs). To do so, it was considering the recent results presented by the National Program for Electric Energy Conservation (PROCEL) to the year 2008, which shows that the program actions' in this period resulted in a Virtual Plant Equivalent of 1049 MW. It was performed a survey of the values of wetland and families displaced by the construction of hydropower plants and, later, it was compared these data with the values found in the literature and, finally, it was established that the actions of energy efficiency are important instruments to avoid (or at least postpone) the social and environmental impacts directly and indirectly that affects the whole society. Thus, it is suggested that there is a stimulus in relation to energy efficiency actions, what is observed nowadays in Brazil is that these actions are negligible before the potential that exists at industrial, commercial and residential sectors. (author)

  19. Determinación y análisis comparativo de gasto cardíaco en enfermos críticos mediante Doppler transesofágico y termodilución en bolos: Experiencia preliminar Comparison of cardiac output measurement in critical patients using transesophageal Doppler or thermodilution: A preliminary report

    Max Andresen H

    2005-07-01

    Full Text Available Background: Cardiac output can be measured non invasively by transesophageal Doppler. This is an alternative to measure it by thermodilution with a catheter in the pulmonary artery. Aim: To compare both methods of cardiac output measurement. Material and methods: Simultaneous measurement of cardiac output by transesophageal Doppler and thermodilution with a catheter in the pulmonary artery in four male critical patients, aged 60±12 years, hospitalized in a University Hospital. The Bland and Altman method to compare the concordance between two measurements, was used. Results: Forty measurements were performed. The results of both methods had a correlation coefficient of 0.98. According to the Bland and Altman method, the difference between both methods was -0.5 L with a precision of 0.52 L/min (95% confidence interval -1.51 to 0.52 L/min. Considering that a change between two sequential measurements is considered significant when the difference is more than 15%, both measurements agreed in 83% of cases, that there was a change in cardiac output. Conclusions:Transesophageal Doppler is a promising non invasive technique to measure cardiac output in critical care patients. It becomes a valid alternative to the thermodilution technique. This preliminary experience must be confirmed in a larger series

  20. Effect of the welding process on the microstructure and microhardness of API 5L X80 steel welded joint used for oil transportation pipeline; Efeito do processo de soldagem sobre a microestrutura e a microdureza de juntas soldadas de aco API 5L X80 usado em tubulacoes para transporte de petroleo

    Alves, R.T.P.; Albuquerque, S.F. [Universidade Federal de Campina Grande (UFCG), PB (Brazil); Maciel, T.M.; Almeida, D.M.; Santos, M.A.

    2008-07-01

    This study had as objective to evaluate the microstructure and microhardness of API 5L X80 steel welded joints, used for pipelines to transport oil and gas, using the Shield Metal Arc Welding process with pre- heating temperature of 200 deg C and 400 deg C and the AWS E8010G electrode as filler metal. For this, besides the microhardness of the welded joint, the weld metals percentiles of micro-constituents and of columnar and regenerated grains and the medium size and extension of the heat affected zone were evaluated. The percentage of acicular ferrite in weld metal ranged from 13% to 33% which generated values of microhardness from 114 HV to 309 HV. (author)

  1. Study of carbonitriding thermochemical treatment by plasma screen in active with pressures main austenitic stainless steels AISI 409 and AISI 316L; Estudo do tratamento termoquimico de carbonitretacao por plasma em tela ativa com pressoes variaveis nos acos inoxidaveis austenitico AISI 316L e ferririco AISI 409

    Melo, M.S.; Oliveira, A.M.; Leal, V.S.; Sousa, R.R.M. de; Alves Junior, C. [Centro Federal de Educacao Tecnologica do Maranhao (CEFET/MA), Sao Luis, MA (Brazil); Centro Federal de Educacao Tecnologica do Piaui (CEFET/PI), Teresina, PI (Brazil); Universidade Federal do Rio Grande do Norte (DF/UFRN), Natal, RN (Brazil). Dept. de Fisica. Labplasma

    2010-07-01

    The technique called Active Screen Plasma Nitriding (ASPN) is being used as an alternative once it offers several advantages with respect to conventional DC plasma. In this method, the plasma does not form directly in the sample's surface but on a screen, in such a way that undesired effects such as the edge effect is minimized. Stainless steels present not very satisfactory wearing characteristics. However, plasma carbonitriding has been used as to improve its resistance to wearing due to the formation of a fine surface layer with good properties. In this work, samples of stainless steel AISI 316L and AISI 409 were treated at pressures of 2.5 and 5 mbar. After the treatments they were characterized by microhardness, microscopy and Xray diffraction. Microscopy and hardness analysis showed satisfactory layers and toughness in those steels. (author)

  2. Desarrollo de producto sobre la base de harinas de cereales y leguminosa para niños celíacos entre 6 y 24 meses; II: Propiedades de las mezclas Product development on the basis of cereal and leguminous flours to coeliac disease in children aged 6-24 months; II: properties of the mixtures

    P. Cerezal Mezquita

    2011-02-01

    Full Text Available Las formulaciones alimenticias de alto contenido proteico, aportado por una mezcla de harinas a partir de dos cultivos andinos, quinua (Chenopodium quinua Willd y lupino (Lupi-nus albus L, con dos cereales tradicionales maíz (Zea mays L. y arroz (Oryza sativa L., conllevaron a la preparación de una 'mezcla dulce' para la elaboración de queques y otra "mezcla postre" saborizada con plátano, que puede ser preparada con agua o con leche, constituyeron una buena alternativa como suplemento alimenticio para la nutrición de niños entre 6 y 24 meses que sufren la enfermedad celíaca, ya que contribuyen al mejoramiento de la calidad de la proteína, por compensación de los aminoácidos esenciales, son de bajo costo y permite un aumento en la disponibilidad de productos para los niños intolerantes al gluten. Se realizó la evaluación de algunas propiedades físicas, químicas, reológicas, mecánicas y de fluidez, así como el color de estas mezclas para un período de conservación de 90 días. Al finalizar el almacenamiento, la mezcla dulce resultó ser de "poco flujo" y la mezcla postre pasó de "poco flujo" a "flujo fácil". La viscosidad para la mezcla postre, con sus dos tipos de diluyentes, agua y leche, presentó un comportamiento de fluido pseudoplástico. Se pudo estimar que el tiempo de vida útil de las mezclas sería de 9 meses antes de llegar al límite de rancidez (10 mEq de oxígeno/kg de grasa, que inhabilitaría el producto para el consumo. Las coordenadas de color CIEL*a*b* no presentaron diferencias significativas manteniéndose el color en una tonalidad "beige".The nutritional formulations of high protein content, provided by a flour mixture from two Andean cultures, quinua (Chenopodium quinua Willd and lupino (Lupinus albus L, with two traditional cereals, maize (Zea mays L. and rice (Oryza sativa L., entailed to the preparation of a "sweet mixture" for the elaboration of "queques" and another "dessert mixture" flavoured with banana, that can be prepared with water or milk, constituted a good alternative as food supplement for the nutrition of children aged 6-24 months who suffer from celiac disease, since they contribute to the quality improvement of the protein, by essential amino acids compensation, they are of low cost and allow an increase in availability of products for gluten-intolerant children. Some physical, chemical, rheological, mechanical and fluidity properties, as well as the color of these mixtures for a period of conservation of 90 days were evaluated. At the end of the storage, the sweet mixture turned out to be of "little flow" and the dessert mixture changed from "little flow" to "easy flow". Viscosity for the dessert mixture, with its two types of dilutions, water and milk, presented a behavior of pseudoplastic fluid. It was possible to guess that the time of shelf life of the mixtures would be of 9 months before achieving the rancidity limit (10 mEq of oxigen/kg of fat, which would disqualify the product for consumption. The CIEL*a*b* color coordinates did not show significant differences keeping the colour in "a beige" tonality.

  3. Alabama Physicians and Accountable Care Organizations: Will What We Don't Know Hurt Us?

    Powell, M Paige; Post, Lindsey R; Bishop, Blake A

    2016-01-01

    Accountable care organizations (ACOs) were designed to improve the quality of care delivered to Medicare beneficiaries while also halting the growth in Medicare spending. Many existing health systems in the Northeast, Midwest, and West have formed ACOs, whereas implementation in Southern states has been slower. The study team conducted a survey of all physician members of the Medical Association of the State of Alabama to determine the likelihood of their participation in an ACO and their attitudes toward some of the characteristics, such as quality measures, regulations, and risks versus rewards. The team found that many physicians reported a lack of knowledge about these areas. Physicians who reported that they were either likely or not likely to participate overwhelmingly held unfavorable attitudes about ACOs. It would be advantageous for Alabama physicians to become more knowledgeable about ACOs in the case that they become a more predominant form of care delivery in the future. PMID:25414377

  4. Phenotype of asthma-chronic obstructive pulmonary disease overlap syndrome.

    Rhee, Chin Kook

    2015-07-01

    Many patients with asthma or chronic obstructive pulmonary disease (COPD) have overlapping characteristics of both diseases. By spirometric definition, patients with both fixed airflow obstruction (AO) and bronchodilator reversibility or fixed AO and bronchial hyperresponsiveness can be considered to have asthma-COPD overlap syndrome (ACOS). However, patients regarded to have ACOS by spirometric criteria alone are heterogeneous and can be classified by phenotype. Eosinophilic inflammation, a history of allergic disease, and smoke exposure are important components in the classification of ACOS. Each phenotype has a different underlying pathophysiology, set of characteristics, and prognosis. Medical treatment for ACOS should be tailored according to phenotype. A narrower definition of ACOS that includes both spirometric and clinical criteria is needed. PMID:26161009

  5. SWARM INTELLIGENCE FROM NATURAL TO ARTIFICIAL SYSTEMS: ANT COLONY OPTIMIZATION

    O. Deepa

    2016-03-01

    Full Text Available Successful applications coming from biologically inspired algorithm like Ant Colony Optimization (ACO based on artificial swarm intelligence which is inspired by the collective behavior of social insects. ACO has been inspired from natural ants system, their behavior, team coordination, synchronization for the searching of optimal solution and also maintains information of each ant. At present, ACO has emerged as a leading metaheuristic technique for the solution of combinatorial optimization problems which can be used to find shortest path through construction graph. This paper describe about various behavior of ants, successfully used ACO algorithms, applications and current trends. In recent years, some researchers have also focused on the application of ACO algorithms to design of wireless communication network, bioinformatics problem, dynamic problem and multi-objective problem.

  6. Transforming healthcare delivery: Why and how accountable care organizations must evolve.

    Chen, Christopher T; Ackerly, D Clay; Gottlieb, Gary

    2016-09-01

    Accountable care organizations (ACOs) have shown promise in reducing healthcare spending growth, but have proven to be financially unsustainable for many healthcare organizations. Even ACOs with shared savings have experienced overall losses because the shared savings bonuses have not covered the costs of delivering population health. As physicians and former ACO leaders, we believe in the concept of accountable care, but ACOs need to evolve if they are to have a viable future. We propose the novel possibility of allowing ACOs to bill fee-for-service for their population health interventions, a concept we call population health billing. Journal of Hospital Medicine 2016;11:658-661. © 2016 Society of Hospital Medicine. PMID:27596543

  7. Ant colony optimisation for economic dispatch problem with non-smooth cost functions

    Pothiya, Saravuth; Kongprawechnon, Waree [School of Communication, Instrumentation and Control, Sirindhorn International Institute of Technology, Thammasat University, P.O. Box 22, Pathumthani (Thailand); Ngamroo, Issarachai [Center of Excellence for Innovative Energy Systems, Faculty of Engineering, King Mongkut' s Institute of Technology Ladkrabang, Bangkok 10520 (Thailand)

    2010-06-15

    This paper presents a novel and efficient optimisation approach based on the ant colony optimisation (ACO) for solving the economic dispatch (ED) problem with non-smooth cost functions. In order to improve the performance of ACO algorithm, three additional techniques, i.e. priority list, variable reduction, and zoom feature are presented. To show its efficiency and effectiveness, the proposed ACO is applied to two types of ED problems with non-smooth cost functions. Firstly, the ED problem with valve-point loading effects consists of 13 and 40 generating units. Secondly, the ED problem considering the multiple fuels consists of 10 units. Additionally, the results of the proposed ACO are compared with those of the conventional heuristic approaches. The experimental results show that the proposed ACO approach is comparatively capable of obtaining higher quality solution and faster computational time. (author)

  8. Asthma COPD Overlap Syndrome on CT Densitometry: A Distinct Phenotype from COPD.

    Gao, Yanli; Zhai, Xiaoli; Li, Kun; Zhang, Hong; Wang, Ying; Lu, Yong; Pan, Zhenyu; Zhang, Lei; Huang, Kewu; Zhai, Renyou

    2016-08-01

    Patients with asthma COPD overlap syndrome (ACOS) are an important but poorly characterized group. This study sought to explore the distinct characteristics of ACOS on CT densitometry. The study population was randomly selected from communities via questionnaires. All participants underwent low-dose volumetric chest CT both before and after bronchodilator administration. Each CT scan was performed at full-inspiration and full-expiration for CT densitometry. Emphysema index (EI), air trapping (AT), mean lung density (MLD) and total lung volume (TLV) were measured and compared between the ACOS and COPD groups. The distributions of both EI and AT were compared between patients with ACOS and COPD. The variations between the pre- and post-BD measurements observed in patients with ACOS were compared with those in patients with COPD. A total of 71 patients completed the study, including 32 patients with COPD and 39 patients with ACOS. The patients with ACOS exhibited lower EI and more upper-zone-predominant EI distributions, compared with the patients with COPD. No significant differences were exhibited in AT and its distribution. Following bronchodilator administration, the variations in AT and expiratory MLD were greater in patients with ACOS than in patients with COPD. No differences were observed in the variations of EI and inspiratory MLD. Our results indicate that patients with ACOS have lower extent of emphysema and different emphysema distribution, as well as greater post-BD variations in air trapping, compared with patients with COPD. These findings suggest that CT densitometry characterizes ACOS as a distinct phenotype from COPD. PMID:26742511

  9. Identification and Characterization of a Novel Alpaca Respiratory Coronavirus Most Closely Related to the Human Coronavirus 229E

    Sharon K. Hietala

    2012-12-01

    Full Text Available In 2007, a novel coronavirus associated with an acute respiratory disease in alpacas (Alpaca Coronavirus, ACoV was isolated. Full-length genomic sequencing of the ACoV demonstrated the genome to be consistent with other Alphacoronaviruses. A putative additional open-reading frame was identified between the nucleocapsid gene and 3'UTR. The ACoV was genetically most similar to the common human coronavirus (HCoV 229E with 92.2% nucleotide identity over the entire genome. A comparison of spike gene sequences from ACoV and from HCoV-229E isolates recovered over a span of five decades showed the ACoV to be most similar to viruses isolated in the 1960’s to early 1980’s. The true origin of the ACoV is unknown, however a common ancestor between the ACoV and HCoV-229E appears to have existed prior to the 1960’s, suggesting virus transmission, either as a zoonosis or anthroponosis, has occurred between alpacas and humans.

  10. Serial position learning effects in patients with aneurysms of the anterior communicating artery.

    Stefanova, Elka; Kostic, Vladimir S; Ziropadja, Ljubomir; Markovic, Milan; Ocic, Gordana

    2002-08-01

    Ruptured and repaired Anterior Communicating Artery (ACoA) aneurysm can result in devastating impairments involving memory, executive function, confabulation, and personality changes. This study tested serial position learning effects (SPEs) in patients following repaired and ruptured ACoA aneurysm, using results on the Rey Auditory Verbal Learning Test (RAVLT). Thirty patients with ruptured aneurysms of the ACoA and 31 matched controls were included in the study. The primacy-recency effects were maintained during five learning trials in ACoA group, albeit at an overall lower level than in the controls. There was no difference in primacy-recency relation across five learning trials in ACoA group. On the delayed recall trial the patient group demonstrated neither a primacy, nor a recency phenomenon, reflecting a lack of recall of any parts of the word list. This kind of primacy-recency profile across learning trials in ACoA group has no similarity with SPE results in frontal lesion groups, or with SPE distributions in other amnesic disorders, despite the fact that memory and executive deficits were evident in our ACoA group. PMID:12187451

  11. A rare anomaly of the anterior communicating artery complex hidden by a large broad-neck aneurysm and disclosed by three-dimensional rotational angiography

    Double fenestration of the anterior communicating artery (ACoA) complex associated with an aneurysm is a very rare finding and is usually caused by ACoA duplication and the presence of a median artery of the corpus callosum (MACC). We present a patient in whom double fenestration was not associated with ACoA duplication or even with MACC, representing therefore, a previously unreported anatomic variation. A 43 year old woman experienced sudden headache and the CT scans showed subarachnoid haemorrhage (SAH). On admission, her clinical condition was consistent with Hunt and Hess grade II. Conventional digital subtraction angiography (DSA) was performed and revealed multiple intracranial aneurysms arising from both middle cerebral arteries (MCA) and from the ACoA. Three-dimensional rotational angiography (3D-RA) disclosed a double fenestration of the ACoA complex which was missed by DSA. The patient underwent a classic pterional approach in order to achieve occlusion of both left MCA and ACoA aneurysms by surgical clipping. The post-operative period was uneventful. A rare anatomical variation characterised by a double fenestration not associated with ACoA duplication or MACC is described. The DSA images missed the double fenestration which was disclosed by 3D-RA, indicating the importance of 3D-RA in the diagnosis and surgical planning of intracranial aneurysms. (author)

  12. Identification and Characterization of a Novel Alpaca Respiratory Coronavirus Most Closely Related to the Human Coronavirus 229E

    Crossley, Beate M.; Mock, Richard E.; Scott A. Callison; Hietala, Sharon K.

    2012-01-01

    In 2007, a novel coronavirus associated with an acute respiratory disease in alpacas (Alpaca Coronavirus, ACoV) was isolated. Full-length genomic sequencing of the ACoV demonstrated the genome to be consistent with other Alphacoronaviruses. A putative additional open-reading frame was identified between the nucleocapsid gene and 3'UTR. The ACoV was genetically most similar to the common human coronavirus (HCoV) 229E with 92.2% nucleotide identity over the entire genome. A comparison of spike ...

  13. Identification and Characterization of a Novel Alpaca Respiratory Coronavirus Most Closely Related to the Human Coronavirus 229E

    Hietala, Sharon K.; Mock, Richard E.; Scott A. Callison; Crossley, Beate M.

    2012-01-01

    In 2007, a novel coronavirus associated with an acute respiratory disease in alpacas (Alpaca Coronavirus, ACoV) was isolated. Full-length genomic sequencing of the ACoV demonstrated the genome to be consistent with other Alphacoronaviruses. A putative additional open-reading frame was identified between the nucleocapsid gene and 3'UTR. The ACoV was genetically most similar to the common human coronavirus (HCoV) 229E with 92.2% nucleotide identity over the entire genome. A comparison of s...

  14. Acetate selective fluorescent turn-on sensors derived using vitamin B6 cofactor pyridoxal-5-phosphate

    Sharma, Darshna; Kuba, Aman; Thomas, Rini; Ashok Kumar, S. K.; Kuwar, Anil; Choi, Heung-Jin; Sahoo, Suban K.

    2016-03-01

    Two new Schiff base receptors have been synthesized by condensation of pyridoxal-5-phosphate with 2-aminophenol (L1) or aniline (L2). In DMSO, the receptors showed both chromogenic and 'turn-on' fluorescence responses selectively in the presence of AcO- and F-. However, in mixed DMSO-H2O medium, the receptors showed AcO- selective 'turn-on' fluorescence without any interference from other tested anions including F-. The detection limit for AcO- was found to be 7.37 μM and 22.9 μM using the receptors L1 and L2, respectively.

  15. A Survey Paper on Solving TSP using Ant Colony Optimization on GPU

    Khushbu Khatri

    2014-12-01

    Full Text Available Ant Colony Optimization (ACO is meta-heuristic algorithm inspired from nature to solve many combinatorial optimization problem such as Travelling Salesman Problem (TSP. There are many versions of ACO used to solve TSP like, Ant System, Elitist Ant System, Max-Min Ant System, Rank based Ant System algorithm. For improved performance, these methods can be implemented in parallel architecture like GPU, CUDA architecture. Graphics Processing Unit (GPU provides highly parallel and fully programmable platform. GPUs which have many processing units with an off-chip global memory can be used for general purpose parallel computation. This paper presents a survey on different solving TSP using ACO on GPU.

  16. A Study of Different Quality Evaluation Functions in the cAnt-MinerPB Classification Algorithm

    Medland, Matthew; Otero, Fernando E. B.

    2012-01-01

    Ant colony optimization (ACO) algorithms for classification in general employ a sequential covering strategy to create a list of classification rules. A key component in this strategy is the selection of the rule quality function, since the algorithm aims at creating one rule at a time using an ACO-based procedure to search the best rule. Recently, an improved strategy has been proposed in the cAnt-MinerPB algorithm, where an ACO-based procedure is used to create a complete list of rules inst...

  17. Governance issues in the transition to accountable care: a case study of Silver Cross Hospital.

    Morrissette, Stephen G

    2012-01-01

    Recent developments in healthcare reform legislation and in the private-payer marketplace have increased impetus toward clinical integration. Industry changes require that healthcare delivery institutions confront fundamental scope and scale structural issues that may lead to increased vertical integration. To accomplish integration, firms must decide the organizational form of integration (alliance or merger/acquisition). One form of integration, accountable care organizations (ACOs), has featured prominently in recent legislation. Clinical integration and ACOs present significant shared-governance challenges that must be understood by hospital boards. The author outlines these governance issues using a case study of Silver Cross Hospital's governance structure for its ACO. PMID:23216264

  18. Examining the Solution for Solving Optimization Problems using Swarm Intelligence and Its Applications

    Selvi, V; Dr. R. Umarani

    2012-01-01

    - SI is a computational and collective behavioral metaphor that is used for solving problems. The problems can be solved by SI by taking ants, termites, bees and wasps as an example. The application of SI algorithm are ACO, PSO and ABC which have been already applied to solve real world optimization problems in engineering. ACO is a member of SI in which ACO is inspired by the behaviour of ant colonies and it constitutes some metaheuristic optimization. ACO’s aim is to search for an optimal p...

  19. The aconitate hydratase family from Citrus

    Cercos Manuel

    2010-10-01

    Full Text Available Abstract Background Research on citrus fruit ripening has received considerable attention because of the importance of citrus fruits for the human diet. Organic acids are among the main determinants of taste and organoleptic quality of fruits and hence the control of fruit acidity loss has a strong economical relevance. In citrus, organic acids accumulate in the juice sac cells of developing fruits and are catabolized thereafter during ripening. Aconitase, that transforms citrate to isocitrate, is the first step of citric acid catabolism and a major component of the citrate utilization machinery. In this work, the citrus aconitase gene family was first characterized and a phylogenetic analysis was then carried out in order to understand the evolutionary history of this family in plants. Gene expression analyses of the citrus aconitase family were subsequently performed in several acidic and acidless genotypes to elucidate their involvement in acid homeostasis. Results Analysis of 460,000 citrus ESTs, followed by sequencing of complete cDNA clones, identified in citrus 3 transcription units coding for putatively active aconitate hydratase proteins, named as CcAco1, CcAco2 and CcAco3. A phylogenetic study carried on the Aco family in 14 plant species, shows the presence of 5 Aco subfamilies, and that the ancestor of monocot and dicot species shared at least one Aco gene. Real-time RT-PCR expression analyses of the three aconitase citrus genes were performed in pulp tissues along fruit development in acidic and acidless citrus varieties such as mandarins, oranges and lemons. While CcAco3 expression was always low, CcAco1 and CcAco2 genes were generally induced during the rapid phase of fruit growth along with the maximum in acidity and the beginning of the acid reduction. Two exceptions to this general pattern were found: 1 Clemenules mandarin failed inducing CcAco2 although acid levels were rapidly reduced; and 2 the acidless "Sucreña" orange

  20. Ant colony optimisation for resource searching in dynamic peer-to-peer grids

    Krynicki, Kamil; Jaén Martínez, Francisco Javier; Mocholi Agües, Jose Antonio

    2014-01-01

    The applicability of peer-to-peer (p2p) in the domain of grid computing has been an important subject over the past years. Nevertheless, the sole merger between p2p and the concept of grid is not sufficient to guarantee non-trivial efficiency. Some claim that ant colony optimisation (ACO) algorithms might provide a definite answer to this question. However, the use of ACO in grid networks causes several problems. The first and foremost stems out of the fact that ACO algorithms usually perform...

  1. Bug bites and stings: When to see a dermatologist

    Full Text Available ... a practice Choosing a derm practice EHR & meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule ... does it work PQRS reporting Qualify for meaningful use FAQs PM webinars Quality care & guidelines Clinical guidelines ...

  2. How to Stop Biting Your Nails

    Full Text Available ... a practice Choosing a derm practice EHR & meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule ... does it work PQRS reporting Qualify for meaningful use FAQs PM webinars Quality care & guidelines Clinical guidelines ...

  3. Optimum culture medium composition for lipopeptide production by Bacillus subtilis using response surface model-based ant colony optimization

    J Satya Eswari; M Anand; C Venkateswarlu

    2016-01-01

    Central composite rotatable design (CCRD) of experiments was used to obtain data for Lipopeptide and Biomass concentrations from fermentation medium containing the following five components: glucose,monosodium glutamate, yeast extract,MgSO4·7H2O, and K2HPO4. Data was used to develop a second order regression response surface model (RSM) which was coupled with ant colony optimization (ACO) to optimize the media compositions so as to enhance the productivity of lipopeptide. The optimized media by ACO was found to yield 1.501 g/L of lipopeptide concentration which was much higher compared to 1.387 g/L predicted by Nelder–Mead optimization (NMO). The optimum from ACO was validated experimentally. RSM-based ACO is thus shown to be an effective tool for medium optimization of biosurfactant production.

  4. How to Stop Biting Your Nails

    Full Text Available ... meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule MACRA resource center PQRS reporting 2016 reporting ... Medicare physician payment MACRA implementation Alternative payment models Fee schedule State policy Legislative Conference Position statements SkinPAC ...

  5. Bug bites and stings: When to see a dermatologist

    Full Text Available ... meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule MACRA resource center PQRS reporting 2016 reporting ... Medicare physician payment MACRA implementation Alternative payment models Fee schedule State policy Legislative Conference Position statements SkinPAC ...

  6. How to Stop Biting Your Nails

    Full Text Available ... education resources MDs and DOs FAQs Video library Practice tools Coding Ask a coding expert Common coding ... coding manuals and webinars AADCoding Today Running a practice Choosing a derm practice EHR & meaningful use ACOs & ...

  7. Bug bites and stings: When to see a dermatologist

    Full Text Available ... education resources MDs and DOs FAQs Video library Practice tools Coding Ask a coding expert Common coding ... coding manuals and webinars AADCoding Today Running a practice Choosing a derm practice EHR & meaningful use ACOs & ...

  8. How to Stop Biting Your Nails

    Full Text Available ... a derm practice EHR & meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule MACRA resource center ... plans and activities Video library Find a dermatologist Home Public and patients Skin, hair, and nail care ...

  9. Bug bites and stings: When to see a dermatologist

    Full Text Available ... a derm practice EHR & meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule MACRA resource center ... plans and activities Video library Find a dermatologist Home Public and patients Skin, hair, and nail care ...

  10. Size and albedo distributions of asteroids in cometary orbits using WISE data

    Licandro, J.; Alí-Lagoa, V.; Tancredi, G.; Fernández, Y.

    2016-01-01

    Context. Determining whether asteroids in cometary orbits (ACOs) are dormant or extinct comets is relevant for understanding the end-states of comets and the sizes of the comet population. Aims: We intend to study the value distributions of effective diameter (D), beaming parameter (η), and visible geometric albedo (pV) of ACO populations, which can be derived from NASA's Wide-field Infrared Explorer (WISE) observations, and we aim to compare these with the same, independently determined properties of the comets. Methods: The near-Earth asteroid thermal model (NEATM) is used with WISE data and the absolute magnitude (H) of the ACOs to compute the D, pV and η. Results: We obtained D and pV for 49 ACOs in Jupiter family cometary orbits (JF-ACOs) and 16 ACOs in Halley-type cometary orbits (Damocloids). We also obtained the infrared beaming parameter η for 45 of them. All but three JF-ACOs (95% of the sample) present a low albedo compatible with a cometary origin. The pV and η distributions of both ACO populations are very similar. For the entire sample of ACOs, the mean geometric albedo is p̅V = 0.05±0.02, (p̅V = 0.05±0.01 and p̅V = 0.05±0.02 for JF-ACOs and for Damocloids, respectively) compatible with a narrow albedo distribution similar to that of the Jupiter family comets (JFCs), with a p̅V ~ 0.04. The mean beaming parameter is η̅ = 1.0±0.2. We find no correlations between D, pV, or η. We also compare the cumulative size distribution (CSD) of ACOs, Centaurs, and JFCs. Although the Centaur sample contains larger objects, the linear parts in their log-log plot of the CSDs presents a similar cumulative exponent (β = 1.85 ± 0.30 and 1.76 ± 0.35, respectively). The CSD for Damocloids presents a much shallower exponent β = 0.89 ± 0.17. Conclusions: The pV- and η-value distributions of ACOs are very similar to those of JF comet (JFCs) nuclei. The ACOs in Tancredi's list are the best possible candidates to be dormant/inactive comets. The CSD for JF-ACOs

  11. The ephemeral accountable care organization-an unintended consequence of the Medicare shared savings program.

    Harvey, H Benjamin; Gowda, Vrushab; Gazelle, G Scott; Pandharipande, Pari V

    2014-02-01

    A fundamental element of health care payment reform under the Affordable Care Act is the development of Accountable Care Organizations (ACOs). The ACO model employs shared-risk contracts to better align the interests of health care providers and payers with the intent of driving efficiency and quality in care. The Medicare Shared Savings Program is the most popular of the Medicare ACO programs, with over 200 health systems across the nation participating at this time. However, a pitfall in the way that the Medicare Shared Savings Program is structured, specifically the benchmarking and rebasing method, could make it difficult for even top-performing ACOs to achieve sustained success, thereby threatening the long-term viability of the program. In this paper, we present this pitfall to the radiology community as well as potential solutions that can be considered by CMS moving forward. PMID:24360903

  12. Optimatization of transient transformation methods to study gene expression in Musa acuminata (AAA group) cultivar Ambon Lumut

    Prayuni, Kinasih; Dwivany, Fenny M.

    2015-09-01

    Banana is classified as a climateric fruit, whose ripening is regulated by ethylene. Ethylene is synthesized from ACC (1-aminocyclopropane-1-carboxylic acid) by ACC oxidase enzyme which is encoded by ACO gene. Controling an important gene expression in ethylene biosynthesis pathway has became a target to delay the ripening process. Therefore in the previous study we have designed a MaACO-RNAi construct to control MaACO gene expression. In this research, we study the effectiveness of different transient transformation methods to deliver the construct. Direct injection, with or no vaccum infiltration methods were used to deliver MaACO-RNAi construct. All of the methods succesfully deliver the construct into banana fruits based on RT-PCR result.

  13. Deep ocean CTD data 2011-2013 from the Aloha Cabled Observatory (NODC Accession 0123115)

    National Oceanic and Atmospheric Administration, Department of Commerce — The ALOHA Cabled Observatory (ACO) is a system of hardware and software that extends electric power and the Internet offshore, supporting sustained real-time...

  14. Deep ocean current profiles, water temperatures, and echo amplitudes from bottom-moored ADCP during 2011-2013 of the Aloha Cabled Observatory (NODC Accession 0123608)

    National Oceanic and Atmospheric Administration, Department of Commerce — The ALOHA Cabled Observatory (ACO) is a system of hardware and software that extends electric power and the Internet offshore, supporting sustained real-time...

  15. An Ant Colony Optimization Algorithm for Microwave Corrugated Filters Design

    Ivan A. Mantilla-Gaviria

    2013-01-01

    Full Text Available A practical and useful application of the Ant Colony Optimization (ACO method for microwave corrugated filter design is shown. The classical, general purpose ACO method is adapted to deal with the microwave filter design problem. The design strategy used in this paper is an iterative procedure based on the use of an optimization method along with an electromagnetic simulator. The designs of high-pass and band-pass microwave rectangular waveguide filters working in the C-band and X-band, respectively, for communication applications, are shown. The average convergence performance of the ACO method is characterized by means of Monte Carlo simulations and compared with that obtained with the well-known Genetic Algorithm (GA. The overall performance, for the simulations presented herein, of the ACO is found to be better than that of the GA.

  16. Examining the Solution for Solving Optimization Problems using Swarm Intelligence and Its Applications

    V. Selvi

    2012-06-01

    Full Text Available - SI is a computational and collective behavioral metaphor that is used for solving problems. The problems can be solved by SI by taking ants, termites, bees and wasps as an example. The application of SI algorithm are ACO, PSO and ABC which have been already applied to solve real world optimization problems in engineering. ACO is a member of SI in which ACO is inspired by the behaviour of ant colonies and it constitutes some metaheuristic optimization. ACO’s aim is to search for an optimal path with the help of graph. In PSO, a solution of continuous optimization problems can be solved , because PSO is population based stochastic optimization techniques for the solution of continuous optimization problem. In ABC the solution for the problem is found with help of foraging behaviour of honey bees. It is also swarm based meta heuristic algorithm. This paper presents the experimental verification of ACO and EACO.

  17. Performance evaluation of ant colony optimization-based solution strategies on the mixed-model assembly line balancing problem

    Akpinar, Sener; Mirac Bayhan, G.

    2014-06-01

    The aim of this article is to compare the performances of iterative ant colony optimization (ACO)-based solution strategies on a mixed-model assembly line balancing problem of type II (MMALBP-II) by addressing some particular features of real-world assembly line balancing problems such as parallel workstations and zoning constraints. To solve the problem, where the objective is to minimize the cycle time (i.e. maximize the production rate) for a predefined number of workstations in an existing assembly line, two ACO-based approaches which differ in the mission assigned to artificial ants are used. Furthermore, each ACO-based approach is conducted with two different pheromone release strategies: global and local pheromone updating rules. The four ACO-based approaches are used for solving 20 representative MMALBP-II to compare their performance in terms of computational time and solution quality. Detailed comparison results are presented.

  18. Ethical Practice Under Accountable Care.

    Graber, Abraham D; Bhandary, Asha; Rizzo, Matthew

    2016-06-01

    Accountable Care Organizations (ACOs) are a key mechanism of the Patient Protection and Affordable Care Act (PPACA). ACOs will influence incentives for providers, who must understand these changes to make well-considered treatment decisions. Our paper defines an ethical framework for physician decisions and action within ACOs. Emerging ethical pressures providers will face as members of an ACO were classified under major headings representing three of the four principles of bioethics: autonomy, beneficence, and justice (no novel conflicts with non-maleficence were identified). Conflicts include a bias against transient populations, a motive to undertreat conditions lacking performance measures, and the mandate to improve population health incentivizing life intrusions. After introducing and explaining each conflict, recommendations are offered for how providers ought to precede in the face of novel ethical choices. Our description of novel ethical choices will help providers know what to expect and our recommendations can guide providers in choosing well. PMID:26002491

  19. Parameter estimation of Lorenz chaotic system using a hybrid swarm intelligence algorithm

    Lazzús, Juan A.; Rivera, Marco; López-Caraballo, Carlos H.

    2016-03-01

    A novel hybrid swarm intelligence algorithm for chaotic system parameter estimation is present. For this purpose, the parameters estimation on Lorenz systems is formulated as a multidimensional problem, and a hybrid approach based on particle swarm optimization with ant colony optimization (PSO-ACO) is implemented to solve this problem. Firstly, the performance of the proposed PSO-ACO algorithm is tested on a set of three representative benchmark functions, and the impact of the parameter settings on PSO-ACO efficiency is studied. Secondly, the parameter estimation is converted into an optimization problem on a three-dimensional Lorenz system. Numerical simulations on Lorenz model and comparisons with results obtained by other algorithms showed that PSO-ACO is a very powerful tool for parameter estimation with high accuracy and low deviations.

  20. Sustainable competitive advantage for accountable care organizations.

    Macfarlane, Michael Alex

    2014-01-01

    In the current period of health industry reform, accountable care organizations (ACOs) have emerged as a new model for the delivery of high-quality and cost-effective healthcare. However, few ACOs operate in direct competition with one another, and the accountable care business model has yet to present a means of continually developing new marginal value for patients and network partners. With value-based purchasing and patient consumerism strengthening as market forces, ACOs must build organizational sustainability and competitive advantage to meet the value demands set by customers and competitors. This essay proposes a strategy, adapted from the disciplines of agile software development and Lean product development, through which ACOs can engage internal and external customers in the development of new products that will provide sustainability and competitive advantage to the organization by decreasing waste in development, promoting specialized knowledge, and closely targeting customer value. PMID:25154124

  1. How to Stop Biting Your Nails

    Full Text Available ... EHR & meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule MACRA resource center PQRS reporting 2016 ... Indoor tanning Network adequacy Impacted states Private payer Medicare physician payment MACRA implementation Alternative payment models Fee ...

  2. Bug bites and stings: When to see a dermatologist

    Full Text Available ... EHR & meaningful use ACOs & medical homes Teledermatology Compliance Medicare fee schedule MACRA resource center PQRS reporting 2016 ... Indoor tanning Network adequacy Impacted states Private payer Medicare physician payment MACRA implementation Alternative payment models Fee ...

  3. Accountable Care Organizations: Integrated Care Meets Market Power.

    Scheffler, Richard M

    2015-08-01

    Will accountable care organizations (ACOs) deliver high-quality care at lower costs? Or will their potential market power lead to higher prices and lower quality? ACOs appear in various forms and structures with financial and clinical integration at their core; however, the tools to assess their quality and the incentive structures that will determine their success are still evolving. Both market forces and regulatory structures will determine how these outcomes emerge. This introduction reviews the evidence presented in this special issue to tackle this thorny trade-off. In general the evidence is promising, but the full potential of ACOs to improve the health care delivery system is still uncertain. This introductory review concludes that the current consensus is to let ACOs grow, anticipating that they will make a contribution to improve our poor-quality and high-cost delivery system. PMID:26124304

  4. Accountable Care Organizations and Antitrust Enforcement: Promoting Competition and Innovation.

    Feinstein, Deborah L; Kuhlmann, Patrick; Mucchetti, Peter J

    2015-08-01

    The antitrust laws stand to protect consumers of health care services from conduct that would raise prices, lower quality, and decrease innovation by lessening competition. Importantly, though, vigorous antitrust enforcement does not impede accountable care organizations (ACOs) and similar collaborations that advance these same goals of better and more efficient care; in fact, by fostering competitive markets, the antitrust laws encourage such initiatives. This article summarizes the legal framework that the federal antitrust agencies - the Federal Trade Commission and the Antitrust Division of the US Department of Justice - use to analyze ACOs and other collaborations among health care providers. It outlines the guidance provided by the federal antitrust agencies concerning when ACOs and other provider collaborations likely would harm competition and consumers. In addition, it reviews common antitrust issues that can arise with ACOs and provides examples of enforcement actions that have prevented health care providers from taking or continuing anticompetitive actions. PMID:26124309

  5. Free electron laser in storage rings

    Investigations on the development of a free electron laser, carried out in ACO storage ring, are reported. The emission of synchrotron radiation is obtained from the interaction of relativistic charged particles with the magnetic field of the undulator. The synchrotron radiation is stored in a cavity, where interaction with electrons occurs. From the amplification of light waves, the laser radiation is then obtained. The changes in the electron wave packets induced by LEL experiment, carried out in ACO storage ring, are reported. A better understanding of the saturation mechanism, which dictates laser equilibrium, is obtained. Experiments in Super ACO were carried out and the following topics, on the construction of the laser, were investigated: the development of an optical klystron, gain optimization, the position of the mirrors (concerning the radiation from the undulator). This work allowed the construction of a 600 MeV free electron laser, at Super ACO. The development of a laser involving UV range radiation, is considered

  6. [Cognitive dysfunction following anterior communicating artery aneurysm rupture. Comparison with alcoholic Korsakoff syndrome on neuropsychological performance].

    Mimura, M; Kato, M; Yoshimasu, H; Kashima, H

    1995-08-01

    The present study aims to compare neuropsychological performance of patients following anterior communicating artery aneurysm rupture (ACoA) with that of patients with alcoholic Korsakoff syndrome (AKS). Fifteen ACoA patients and ten age-and education-matched AKS patients were included in the study. All the patients were tested at least one year post onset of their illness at a stable condition. The WAIS and forward digit span scores of AKS were also matched to ACoA, and simple attention and general intelligence were well preserved both in ACoA and AKS. Frontal function as measured by the Wisconsin card sorting test (Keio version) (KWCST) was equivalently impaired in the two groups. Anterograde memory as measured by Wechsler memory scale subtests, serial seven word learning test, Rey auditory verbal learning test, and logical memorizing test (Luria's paired word-picture association), was more severely impaired in AKS than ACoA in contrast to the comparable attention, intelligence, and frontal function: (1) memory tasks with low correlations to KWCST (serial word learning tasks and paired verbal associates), reflecting primary simple serial memorizing, and (2) memory tasks with high correlations to KWCST (logical memory and logical memorizing), reflecting higher and complicated strategic mnemonic activities. However, the correlations between these anterograde memory subtests and KWCST were substantially equivalent in ACoA and AKS. This suggests that the differences in anterograde amnesia demonstrated in ACoA and AKS may be of quantitative, not of qualitative property. The extent of deficits in semantic encoding as measured by Wickens' release from proactive interference paradigm (PI release) was also milder in ACoA than AKS. Both AKS and ACoA failed to show PI release in contrast to normal PI release demonstrated in age-matched ten healthy subjects. PI release in ACoA, however, was in between AKS and healthy subjects. The results were interpreted in the light of a

  7. Phenotype of asthma-chronic obstructive pulmonary disease overlap syndrome

    Rhee, Chin Kook

    2015-01-01

    Many patients with asthma or chronic obstructive pulmonary disease (COPD) have overlapping characteristics of both diseases. By spirometric definition, patients with both fixed airflow obstruction (AO) and bronchodilator reversibility or fixed AO and bronchial hyperresponsiveness can be considered to have asthma-COPD overlap syndrome (ACOS). However, patients regarded to have ACOS by spirometric criteria alone are heterogeneous and can be classified by phenotype. Eosinophilic inflammation, a ...

  8. A swarm intelligence framework for reconstructing gene networks: searching for biologically plausible architectures

    Poole, Matthew; Kentzoglanakis, Kyriakos

    2011-01-01

    In this paper, we investigate the problem of reverse engineering the topology of gene regulatory networks from temporal gene expression data. We adopt a computational intelligence approach comprising swarm intelligence techniques, namely particle swarm optimization (PSO) and ant colony optimization (ACO). In addition, the recurrent neural network (RNN) formalism is employed for modelling the dynamical behaviour of gene regulatory systems. More specifically, ACO is used for searching the discre...

  9. Kinetics and mechanism of synthetic CoS oxidation process

    Štrbac N.

    2006-01-01

    Full Text Available The results of investigation of kinetics and mechanism for synthetic a-CoS oxidation process are presented in this paper. Based on experimental data obtained using DTA and XRD analysis and constructed PSD diagrams for Co-S-O system, mechanism of synthetic a-CoS oxidation process is suggested. Characteristic kinetic parameters were obtained for experimental isothermal investigations of desulfurization degree using Sharp method.

  10. Trail-Using Ant Behavior Based Energy-Efficient Routing Protocol in Wireless Sensor Networks

    Soon-gyo Jung; Byungseok Kang; Sanggil Yeoum; Hyunseung Choo

    2016-01-01

    Swarm Intelligence (SI) observes the collective behavior of social insects and other animal societies. Ant Colony Optimization (ACO) algorithm is one of the popular algorithms in SI. In the last decade, several routing protocols based on ACO algorithm have been developed for Wireless Sensor Networks (WSNs). Such routing protocols are very flexible in distributed system but generate a lot of additional traffic and thus increase communication overhead. This paper proposes a new routing protocol...

  11. Flip-OFDM for Optical Wireless Communications

    Fernando, Nirmal; Hong, Yi; Viterbo, Emanuele

    2011-01-01

    We consider two uniploar OFDM techniques for optical wireless communications: asymmetric clipped optical OFDM (ACO-OFDM) and Flip-OFDM. Both techniques can be used to compensate multipath distortion effects in optical wireless channels. However, ACO-OFDM has been widely studied in the literature, while the performance of Flip-OFDM has never been investigated. In this paper, we conduct the performance analysis of Flip-OFDM and propose additional modification to the original scheme in order to ...

  12. Automatic Checkout System for Ground Electronics of a Weapon System (Short Communication

    V. Ashok Kumar

    1997-04-01

    Full Text Available An automatic checkout system (ACOS designed and developed for a surface-to-air missile system is described. The system has a built-in self-check and has been extensively used for checking faults in the subsystems of ground electronics. It has resulted in saving a lot of effort in quickly diagnosing and rectifying faults. The salient features of the ACOS have been described and the scope for further work in this area has been outline.

  13. Statistical Approach for Selecting Elite Ants

    S., Raghavendra G

    2012-01-01

    Applications of ACO algorithms to obtain better solutions for combinatorial optimization problems have become very popular in recent years. In ACO algorithms, group of agents repeatedly perform well defined actions and collaborate with other ants in order to accomplish the defined task. In this paper, we introduce new mechanisms for selecting the Elite ants dynamically based on simple statistical tools. We also investigate the performance of newly proposed mechanisms.

  14. Using supercluster geometry as a cosmological probe

    Basilakos, S; Plionis, M

    2001-01-01

    We study the properties of superclusters detected in the Abell/ACO cluster catalogue. We identify the superclusters utilizing the `friend-of-friend' procedure, and then determine supercluster shapes by using the differential geometry approach. We find that the dominant supercluster morphological feature is filamentariness. We compare our Abell/ACO supercluster results with the corresponding ones generated from two different CDM cosmological models in order to investigate statistically which of the latter models best reproduces the observational results.

  15. Accountable Care Organizations in the Era of Healthcare Reform

    2010-01-01

    Under the Patient Protection and Affordable Care Act (PPACA) of 2010, Medicare providers, including physician groups and hospitals, will soon have the option to form accountable care organizations (ACOs) to improve quality and efficiency. ACO participants may share financial gains generated from improved clinical and economic performance, provided that quality goals and patient safeguards are met. Through future regulations, the Centers for Medicare & Medicaid Services (CMS) must implement th...

  16. Data Mining using Advanced Ant Colony Optimization Algorithm and Application to Bankruptcy Prediction

    Vishal Arora; Vadlamani Ravi

    2013-01-01

    Ant Colony Optimization (ACO) is gaining popularity as data mining technique in the domain of Swarm Intelligence for its simple, accurate and comprehensive nature of classification. In this paper the authors propose a novel advanced version of the original ant colony based miner (Ant-Miner) in order to extract classification rules from data. They call this Advanced ACO-Miner (ADACOM). The main goal of ADACOM is to explore the flexibility of using a different knowledge extraction heuristic app...

  17. Elevated CO2 enhances photosynthetic efficiency, ion uptake and antioxidant activity of Gynura bicolor DC. grown in a porous-tube nutrient delivery system under simulated microgravity.

    Wang, M; Liu, H; Dong, C; Fu, Y; Liu, H

    2016-05-01

    It is well known that plants can grow under space conditions, however, perturbations of many biological phenomena have been highlighted due to the effect of altered gravity and its possible interaction with other factors (e.g., CO2 , ion radiation, etc. Our aim was to test whether elevated CO2 could provide 'protection' to Gynura bicolor against the damaging effects of simulated microgravity (SM) on photosynthesis, ion uptake and antioxidant activity. As compared to G. bicolor grown in ambient CO2 with no SM (ACO2 ), growth and yield of the plants increased under elevated ambient CO2 with no SM (ECO2 ) and decreased under ACO2 +SM, whereas there was no significant effect on ECO2 +SM. Reductions in the content of Chl a, carotenoids and Chl a+b were 17.9%, 20.7% and 17.9% under ACO2 +SM, respectively, but under ECO2 there was a significant effect on all photosynthetic pigments except Chl b, compared to ACO2 . Photosynthesis was improved under ECO2 with SM and such an improvement was associated with improved water use efficiency and instantaneous carboxylation efficiency. Furthermore, SM caused a reduction in ion absorption rate, except for Ca(2+) , while ECO2 increased the uptake rate. Finally, the activity of SOD, POD and the content of MDA and H2 O2 were enhanced under SM treatments and were highest in ACO2 +SM. In contrast, T-AOC activity and GSH content significantly declined in ACO2 +SM compared to other treatments. These results suggest that ACO2 is not sufficient to counteract SM impact, but the increase is usually caused by improvement in CO2 nutrition in ECO2 +SM in comparison with ACO2 +SM. PMID:26669703

  18. An agent-based simulation model to study accountable care organizations.

    Liu, Pai; Wu, Shinyi

    2016-03-01

    Creating accountable care organizations (ACOs) has been widely discussed as a strategy to control rapidly rising healthcare costs and improve quality of care; however, building an effective ACO is a complex process involving multiple stakeholders (payers, providers, patients) with their own interests. Also, implementation of an ACO is costly in terms of time and money. Immature design could cause safety hazards. Therefore, there is a need for analytical model-based decision-support tools that can predict the outcomes of different strategies to facilitate ACO design and implementation. In this study, an agent-based simulation model was developed to study ACOs that considers payers, healthcare providers, and patients as agents under the shared saving payment model of care for congestive heart failure (CHF), one of the most expensive causes of sometimes preventable hospitalizations. The agent-based simulation model has identified the critical determinants for the payment model design that can motivate provider behavior changes to achieve maximum financial and quality outcomes of an ACO. The results show nonlinear provider behavior change patterns corresponding to changes in payment model designs. The outcomes vary by providers with different quality or financial priorities, and are most sensitive to the cost-effectiveness of CHF interventions that an ACO implements. This study demonstrates an increasingly important method to construct a healthcare system analytics model that can help inform health policy and healthcare management decisions. The study also points out that the likely success of an ACO is interdependent with payment model design, provider characteristics, and cost and effectiveness of healthcare interventions. PMID:24715674

  19. A Survey Paper on Solving TSP using Ant Colony Optimization on GPU

    Khushbu khatri; Vinit Kumar Gupta

    2014-01-01

    Ant Colony Optimization (ACO) is meta-heuristic algorithm inspired from nature to solve many combinatorial optimization problem such as Travelling Salesman Problem (TSP). There are many versions of ACO used to solve TSP like, Ant System, Elitist Ant System, Max-Min Ant System, Rank based Ant System algorithm. For improved performance, these methods can be implemented in parallel architecture like GPU, CUDA architecture. Graphics Processing Unit (GPU) provides highly parallel and f...

  20. An ant colony optimization algorithm for job shop scheduling problem

    Edson Flórez; Wilfredo Gómez; MSc. Lola Bautista

    2013-01-01

    The nature has inspired several metaheuristics, outstanding among these is Ant Colony Optimization (ACO), which have proved to be very effective and efficient in problems of high complexity (NP-hard) in combinatorial optimization. This paper describes the implementation of an ACO model algorithm known as Elitist Ant System (EAS), applied to a combinatorial optimization problem called Job Shop Scheduling Problem (JSSP). We propose a method that seeks to reduce delays designating th...

  1. Continuous function optimization using hybrid ant colony approach with orthogonal design scheme

    Zhang, J.; Chen, W.; Zhong, J.; Tan, X.; Li, Y.

    2006-01-01

    A hybrid Orthogonal Scheme Ant Colony Optimization (OSACO) algorithm for continuous function optimization (CFO) is presented in this paper. The methodology integrates the advantages of Ant Colony Optimization (ACO) and Orthogonal Design Scheme (ODS). OSACO is based on the following principles: a) each independent variable space (IVS) of CFO is dispersed into a number of random and movable nodes; b) the carriers of pheromone of ACO are shifted to the nodes; c) solution path can be obtained by ...

  2. An Effect and Analysis of Parameter on Ant Colony Optimization for Solving Travelling Salesman Problem

    Km. Shweta; Alka Singh

    2013-01-01

    Ant Colony optimization has proved suitable to solve a wide range of combinatorial optimization(or NP-hard) problems as the Travelling Salesman Problem (TSP). The first step of ACO algorithm is to setthe parameters that drive the algorithm. The parameter has an important impact on the performance of theant colony algorithm. The basic parameters that are used in ACO algorithms are; the relative importance (orweight) of pheromone, the relative importance of heuristics value, initial pheromone v...

  3. Quantitative computed tomography measurements of emphysema for diagnosing asthma-chronic obstructive pulmonary disease overlap syndrome

    Xie, Mengshuang; Wang, Wei; Dou, Shuang; Cui, Liwei; Xiao, Wei

    2016-01-01

    Background The diagnostic criteria of asthma–COPD overlap syndrome (ACOS) are controversial. Emphysema is characteristic of COPD and usually does not exist in typical asthma patients. Emphysema in patients with asthma suggests the coexistence of COPD. Quantitative computed tomography (CT) allows repeated evaluation of emphysema noninvasively. We investigated the value of quantitative CT measurements of emphysema in the diagnosis of ACOS. Methods This study included 404 participants; 151 asthm...

  4. Kinetics and mechanism of synthetic CoS oxidation process

    Štrbac N.; Mihajlović I.; Živković D.; Boyanov B.; Živković Ž.; Cocić M.

    2006-01-01

    The results of investigation of kinetics and mechanism for synthetic a-CoS oxidation process are presented in this paper. Based on experimental data obtained using DTA and XRD analysis and constructed PSD diagrams for Co-S-O system, mechanism of synthetic a-CoS oxidation process is suggested. Characteristic kinetic parameters were obtained for experimental isothermal investigations of desulfurization degree using Sharp method.

  5. Modified Castor Oil as an Epoxy Resin Curing Agent

    Patel, B. P.; H. S. Patel; Patel, S R

    2004-01-01

    A castor oil, an agricultural product, is an unsaturated material. Hence the castor oil is brominated by bromine liquid. The brominated castor oil (BCO) was then reacted with excess of aliphatic diamines viz; ethylene diamine, 1,3-propane diamine and 1,6-hexane diamine. The resultant amino functionalized castor oil (ACO) samples were then characterized by elemental analysis, IR spectral study and number of amino groups. All the three ACO samples were then employed for the curing of commercial...

  6. Tasks Scheduling using Ant Colony Optimization

    A. P. Shanthi

    2012-01-01

    Full Text Available Problem statement: Efficient scheduling of the tasks to heterogeneous processors for any application is critical in order to achieve high performance. Finding a feasible schedule for a given task set to a set of heterogeneous processors without exceeding the capacity of the processors, in general, is NP-Hard. Even if there are many conventional approaches available, people have been looking at unconventional approaches for solving this problem. This study uses a paradigm using Ant Colony Optimisation (ACO for arriving at a schedule. Approach: An attempt is made to arrive at a feasible schedule of a task set on heterogeneous processors ensuring load balancing across the processors. The heterogeneity of the processors is modelled by assuming different utilisation times for the same task on different processors. ACO, a bio-inspired computing paradigm, is used for generating the schedule. Results: For a given instance of the problem, ten runs are conducted based on an ACO algorithm and the average wait time of all tasks is computed. Also the average utilisation of each processor is calculated. For the same instance, the two parameters: average wait time of tasks and utilisation of processors are computed using the First Come First Served (FCFS. The results are tabulated and compared and it is found that ACO performs better than the FCFS with respect to the wait time. Although the processor utilisation is more for some processors using FCFS algorithm, it is found that the load is better balanced among the processors in ACO. There is a marginal increase in the time for arriving at a schedule in ACO compared to FCFS algorithm. Conclusion: This approach to the tasks assignment problem using ACO performs better with respect to the two parameters used compared to the FCFS algorithm but the time taken to come up with the schedule using ACO is slightly more than that of FCFS.

  7. Delivering On Accountable Care: Lessons From A Behavioral Health Program To Improve Access And Outcomes.

    Clarke, RM; Jeffrey, J; Grossman, M.; Strouse, T; Gitlin, M.; Skootsky, SA

    2016-01-01

    Patients with behavioral health disorders often have worse health outcomes and have higher health care utilization than patients with medical diseases alone. As such, people with behavioral health conditions are important populations for accountable care organizations (ACOs) seeking to improve the efficiency of their delivery systems. However, ACOs have historically faced numerous barriers in implementing behavioral health population-based programs, including acquiring reimbursement, recruiti...

  8. RESEARCH ON SOLVING TRAVELLING SALESMAN PROBLEM USING RANK BASED ANT SYSTEM ON GPU

    Khushbu Khatri; Vinit Kumar Gupta

    2015-01-01

    Ant Colony Optimization (ACO) is meta-heuristic algorithm inspired from nature to solve many combinatorial optimization problems such as Travelling Salesman Problem (TSP). There are many versions of ACO used to solve TSP like, Ant System, Elitist Ant System, Max-Min Ant System, Rank based Ant System algorithm. For improved performance, these methods can be implemented in parallel architecture like GPU, CUDA architecture. Graphics Processing Unit (GPU) provides highly parallel and fully progra...

  9. Utilidad de la determinación de la fracción I de la Troponina cardíaca (cTnI, en el diagnóstico de la muerte súbita de origen cardíaco en autopsias forenses Usefulness of cardiac troponin I (cTnI in the diagnosis of sudden cardiac death in forensic autopsies

    E. Navarro

    2007-07-01

    Full Text Available Objetives: To evaluate practical usefulness of cardiac Troponin analysis (cTnI in peripheral blood levels, in order to improve diagnosis of sudden cardiac death in routine forensic cases. Comparing these levels with Myoglobin and MB-CK blood levels in the same type of samples. Material and methods: We have studied 97 medico legal autopsies performed in the Pathology Service of the Institute of Legal Medicine (Alicante. In every case we analyzed sample of serum from peripheral blood (femoral, by Microparticle Enzyme Immunoassay (MEIA Axsym system (Abbott Diagnostics. Causes of death were classified into 6 groups according: 1 Death of cardiac origin (n=42; 2 Traumatic deaths (n=19; 3 Death by asphyxia (n=12; 4 Natural deaths of non-cardiac origin (n=8; 5 Miscellaneous group (n=6, and 6 Traumatic death with Thoracic trauma (n=10. Data was analysed by means of SPSS 14.0 statistical software program (SPSS Inc, 2005. Results: cTnI levels were significantly high in cases of sudden cardiac death, but it were also high in the group of thoracic trauma, which could raise diagnosis problems between these groups, as was shown previously in the literature. Conclusions: The determination of cTnI is more efficient than CKMB and Myoglobine in the diagnosis of sudden cardiac death. However, the elevation of mean levels of this marker in cases of severe thoracic traumatism limits its diagnostic usefulness in these situations.

  10. The role of palliative care in population management and accountable care organizations.

    Smith, Grant; Bernacki, Rachelle; Block, Susan D

    2015-06-01

    By 2021, health care spending is projected to grow to 19.6% of the GDP, likely crowding out spending in other areas. The 2010 Affordable Care Act (ACA) attempts to curb health care spending by incentivizing high-value care through the creation of Accountable Care Organizations (ACOs), which assume financial risk for patient outcomes. With this financial risk, health systems creating ACOs will be motivated to pursue innovative care models that maximize the value of care. Palliative care, as an emerging field with a growing evidence base, is positioned to improve value in ACOs by increasing high-quality care and decreasing costs for the sickest patients. ACO leaders may find palliative care input valuable in optimizing high-quality patient-centered care in the accountable care environment; however, palliative care clinicians will need to adopt new models that extrapolate their direct patient care skills to population management strategies. We propose that palliative care specialists take on responsibilities for working with ACO leaders to broaden their mission for systemwide palliative care for appropriate patients by prospectively identifying patients with a high risk of death, high symptom burden, and/or significant psychosocial dysfunction, and developing targeted, "triggered" interventions to enhance patient-centered, goal-consistent, coordinated care. Developing these new population management competencies is a critical role for palliative care teams in the ACO environment. PMID:25723619

  11. Asthma, COPD and overlap syndrome: a longitudinal study in young European adults.

    de Marco, Roberto; Marcon, Alessandro; Rossi, Andrea; Antó, Josep M; Cerveri, Isa; Gislason, Thorarinn; Heinrich, Joachim; Janson, Christer; Jarvis, Deborah; Kuenzli, Nino; Leynaert, Bénédicte; Probst-Hensch, Nicole; Svanes, Cecilie; Wjst, Matthias; Burney, Peter

    2015-09-01

    We compared risk factors and clinical characteristics, 9-year lung function change and hospitalisation risk across subjects with the asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS), asthma or COPD alone, or none of these diseases.Participants in the European Community Respiratory Health Survey in 1991-1993 (aged 20-44 years) and 1999-2001 were included. Chronic airflow obstruction was defined as pre-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacitynormal on both occasions. Based on their history of respiratory symptoms, spirometry and risk factors, subjects were classified as having asthma alone (n=941), COPD alone (n=166), ACOS (n=218) and none of these (n=5659).Subjects with ACOS shared risk factors and clinical characteristics with subjects with asthma alone, but they had an earlier age of asthma onset. FEV1 change in the ACOS group (-25.9 mL·year(-1)) was similar to that in the asthma group (-25.3 mL·year(-1)), and lower (p<0.001) than in the COPD group (-37.3 mL·year(-1)). ACOS was associated with the highest hospitalisation rate.Among young adults aged 20-44 years, ACOS seems to represent a form of severe asthma, characterised by more frequent hospitalisations, and to be the result of early-onset asthma that has progressed to fixed airflow obstruction. PMID:26113674

  12. Biomedical Image Edge Detection using an Ant Colony Optimization Based on Artificial Neural Networks

    Javad Rahebi

    2011-12-01

    Full Text Available Ant colony optimization (ACO is the algorithm that has inspired from natural behavior of ants life, which the ants leaved pheromone to search food on the ground. In this paper, ACO is introduced for resolving the edge detection in the biomedical image. Edge detection method based on ACO is able to create a matrix pheromone that shows information of available edge in each location of edge pixel which is created based on the movements of a number of ants on the biomedical image. Moreover, the movements of these ants are created by local fluctuation of biomedical image intensity values. The detected edge biomedical images have low quality rather than detected edge biomedical image resulted of a classic mask and won’t result application of these masks to edge detection biomedical image obtained of ACO. In proposed method, we use artificial neuralnetwork with supervised learning along with momentum to improve edge detection based on ACO. The experimental results shows that make use neural network are very effective in edge detection based on ACO.

  13. Structure Learning Algorithm for DBN Transition Networks Based on Ant Colony Optimization%基于蚁群优化的DBN转移网络结构学习算法

    胡仁兵; 翼俊忠; 张鸿勋; 刘椿年

    2009-01-01

    Aiming at the characteristics of dynamic Bayesian transition networks, this paper proposes a structure learning algorithm based on Ant Colony Optimization(ACO) named ACO-DBN-2S by extending the static Bayesian networks structure leaning algorithm I-ACO-B. In ACO-DBN-2S, ants select arcs from the inter-ares between time slices before from the intra-arcs in one slice, and the interval optimization strategy is improved by decreasing the times of optimizatien operation. A number of experiments under standard datasets demonstrate the algorithm can handle large data, and the precision and speed of learning are improved.%针对动态贝叶斯转移网络的特点,以I-ACO-B为基础,提出基于蚁群优化的分步构建转移网络的结构学习算法ACO-DBN-2S.算法将转移网络的结构学习分为时间片之间和时间片内2个步骤进行,通过改进隔代优化策略,减少无效优化次数.标准数据集下的大量实验结果证明,该算法能更有效地处理大规模数据,学习精度和速度有较大改进.

  14. Aprendizaje de Clases de Equivalencia de Redes Bayesianas basado en Búsqueda Competitiva de Hormigas Artificiales

    Henry Arguello

    2014-12-01

    Full Text Available This article proposes an algorithm for learning equivalence classes of Bayesian networks based on a Greed search algorithm and search patterns inspired by competitive ants. Specifically, for the proposed algorithm, we obtained a better approximation between the predicted network and the theoretical network ASIA with respect to previous algorithms for data sets with 20 and 500 samples. On average, the algorithm developed an approximation with respect to Structural Hamming Distance of 10.7% and 5.3% lower than Greedy algorithms and ACO-E respectively to 20 samples, and up to 6.8% lower tan ACO-E algorithm for 500 samples. Furthermore, for 500 samples the number of calls to the scoring function performed by the algorithm proposed was smaller than in the ACO-E algorithm in 90% of the combinations, concluding that there was a reduction in the computational complexity. Finally, we present the results of applying the proposed algorithm to a microarray samples obtained from patients with acute myeloid leukemia (AML with 6 new interactions with statistical dependencies as potential biological interactions with high probability.

  15. A novel hybrid approach based on Particle Swarm Optimization and Ant Colony Algorithm to forecast energy demand of Turkey

    Highlights: ► PSO and ACO algorithms are hybridized for forecasting energy demands of Turkey. ► Linear and quadratic forms are developed to meet the fluctuations of indicators. ► GDP, population, export and import have significant impacts on energy demand. ► Quadratic form provides better fit solution than linear form. ► Proposed approach gives lower estimation error than ACO and PSO, separately. - Abstract: This paper proposes a new hybrid method (HAP) for estimating energy demand of Turkey using Particle Swarm Optimization (PSO) and Ant Colony Optimization (ACO). Proposed energy demand model (HAPE) is the first model which integrates two mentioned meta-heuristic techniques. While, PSO, developed for solving continuous optimization problems, is a population based stochastic technique; ACO, simulating behaviors between nest and food source of real ants, is generally used for discrete optimizations. Hybrid method based PSO and ACO is developed to estimate energy demand using gross domestic product (GDP), population, import and export. HAPE is developed in two forms which are linear (HAPEL) and quadratic (HAPEQ). The future energy demand is estimated under different scenarios. In order to show the accuracy of the algorithm, a comparison is made with ACO and PSO which are developed for the same problem. According to obtained results, relative estimation errors of the HAPE model are the lowest of them and quadratic form (HAPEQ) provides better-fit solutions due to fluctuations of the socio-economic indicators.

  16. Study on ant colony optimization for fuel loading pattern problem

    Modified ant colony optimization (ACO) was applied to the in-core fuel loading pattern (LP) optimization problem to minimize the power peaking factor (PPF) in the modeled 1/4 symmetry PWR core. Loading order was found to be important in ACO. Three different loading orders with and without the adjacent effect between fuel assemblies (FAs) were compared, and it was found that the loading order from the central core is preferable because many selections of FAs to be inserted are available in the core center region. LPs were determined from pheromone trail and heuristic information, which is a priori knowledge based on the feature of the problem. Three types of heuristic information were compared to obtain the desirable performance of searching LPs with low PPF. Moreover, mutation operation, such as the genetic algorithm (GA), was introduced into the ACO algorithm to avoid searching similar LPs because heuristic information used in ACO tends to localize the searching space in the LP problem. The performance of ACO with some improvement was compared with those of simulated annealing and GA. In conclusion, good performance can be achieved by setting proper heuristic information and mutation operation parameter in ACO. (author)

  17. A Stochastic Inversion Method for Potential Field Data: Ant Colony Optimization

    Liu, Shuang; Hu, Xiangyun; Liu, Tianyou

    2014-07-01

    Simulating natural ants' foraging behavior, the ant colony optimization (ACO) algorithm performs excellently in combinational optimization problems, for example the traveling salesman problem and the quadratic assignment problem. However, the ACO is seldom used to inverted for gravitational and magnetic data. On the basis of the continuous and multi-dimensional objective function for potential field data optimization inversion, we present the node partition strategy ACO (NP-ACO) algorithm for inversion of model variables of fixed shape and recovery of physical property distributions of complicated shape models. We divide the continuous variables into discrete nodes and ants directionally tour the nodes by use of transition probabilities. We update the pheromone trails by use of Gaussian mapping between the objective function value and the quantity of pheromone. It can analyze the search results in real time and promote the rate of convergence and precision of inversion. Traditional mapping, including the ant-cycle system, weaken the differences between ant individuals and lead to premature convergence. We tested our method by use of synthetic data and real data from scenarios involving gravity and magnetic anomalies. The inverted model variables and recovered physical property distributions were in good agreement with the true values. The ACO algorithm for binary representation imaging and full imaging can recover sharper physical property distributions than traditional linear inversion methods. The ACO has good optimization capability and some excellent characteristics, for example robustness, parallel implementation, and portability, compared with other stochastic metaheuristics.

  18. QSPR Models of Compound Viscosity Based on Iterative Self-Organizing Data Analysis Technique and Ant Colony Algorithm%基于迭代自组织数据分析算法与蚁群算法建立有机物黏度的QSPR模型

    时静洁; 陈利平; 陈网桦

    2014-01-01

    为了构建310个有机物分子结构与其黏度之间的定量结构-性质关系(QSPR)模型,探讨影响有机物液体黏度的结构因素,首先运用迭代自组织数据分析技术(ISODATA)将样本集初步分类,划分为训练集和测试集,进而应用 DRAGON2.1软件计算310个有机物分子的分子结构描述符,以蚁群算法(ACO)筛选分子描述符,得到5个参数,随后分别采用多元线性回归法(MLR)和支持向量机法(SVM)建立 ACO-MLR 模型和 ACO-SVM 模型.结果表明,非线性 ACO-SVM 模型(相关系数 R 2train=0.9013, R 2test=0.9026)的性能优于线性 ACO-MLR模型(R 2train=0.7680, R 2test=0.8725). ACO-MLR模型和ACO-SVM模型对测试集所得预测值与实验值的相关系数分别为0.934和0.950,预测效果令人满意.本文应用Wil iams图对模型的应用域进行了一定的研究,所建立的模型为工程上提供了一种根据分子结构预测有机物黏度的有效方法.%The aim of this study was to construct a quantitative structure-property relationship model to identify relationships between the molecular structures and viscosities of 310 compounds, as wel as specific structural factors that could affect the viscosities of the compounds. Using an iterative self-organizing data analysis technique, the sample set was preliminarily classified into two sets, including a training set and a test set. The molecular structure descriptors of 310 compounds were calculated using version 2.1 of the Dragon software and subsequently sifted using an ant colony algorithm (ACO), which resulted in the selection of five parameters. Multiple linear regression (MLR) and the support vector machine (SVM) techniques were then used to establish ACO-MLR and ACO-SVM models, respectively. The results showed that the performance of the non-linear ACO-SVM model (correlation coefficient R 2train= 0.9013, R 2test= 0.9026) was superior to the linearACO-MLR model ( R 2train=0.7680, R 2test= 0.8725). The correlation

  19. Metal (Fe, Co, Ni) supported on different aluminas as Fischer-Tropsch catalyst

    Dahlan [Chemistry Education Study Program, Universitas Halu Oleo, Jl. HEA Mokodompit, Kendari 93232 (Indonesia); Marsih, I. Nyoman, E-mail: nyoman@chem.itb.ac.id; Ismunandar [Inorganic and Physical Chemistry Division, Departement of Chemistry, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung 40132 (Indonesia); Makertihartha, I. G. B. N. [Department of Chemical Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung 40132 (Indonesia); Praserthdam, Piyasan; Panpranot, Joongjai [Center of Excellence on Catalysis and Catalytic Reaction Engineering, Department of Chemical Engineering, Chulalongkorn University, 254 Phayathai Road, Bangkok 10330 (Thailand)

    2015-09-30

    This research aimed to compare the physico-chemical properties of the same metal M (M = iron, cobalt, nickel) supported on aluminas with different morphology and pore size as Fischer-Tropsch catalyst. The aluminas applied as support were alumina synthesized through hydrothermal process, alumina formed by pretreatment of catapal and commercial alumina which named as Ahy, Aca, and Aco respectively. Ahy has uniform morphology of nanotubes while Aca and Aco showed non-uniform morphology of particle lumps. The particle lumps of Aca were larger than those of Aco. Ahy, Aca, and Aco respectively has average pore diameter of 2.75, 2.86 and 2.9 nm. Metals were deposited on the supports by incipient-wetness impregnation method. The catalysts were characterized by XRD, H{sub 2}-TPR, and H{sub 2} chemisorption. Catalyst acitivity test for Fischer-Tropsch reaction was carried out in a micro reactor at 200 °C and 1 atm, and molar ratio of H{sub 2}/CO = 2:1. The metal oxide particle size increased in the order M/Aco < M/Aca < M/Ahy. The catalysts reducibility also increased according to the order M/Aco < M/Aca < M/Ahy suggesting that the larger metal oxide particles are more reducible. The number of active site was not proportional to the reducibility because during the reduction, larger metal oxide particles were converted into larger metal particles. On the other hand, the number of active sites was inversely proportional to the particle sizes. The number of active site increased in the order M/Ahy < M/Aco < M/Aca. The catalytic activity also increased in the following order M/Ahy < M/Aco < M/Aca. The activity per active site increased according to the order M/Aca < M/Aco < M/Ahy meaning that for M/Ahy, a little increase in active site will lead to a significance increase in catalytic activity. It showed that Ahy has potential for the better support.

  20. Metal (Fe, Co, Ni) supported on different aluminas as Fischer-Tropsch catalyst

    This research aimed to compare the physico-chemical properties of the same metal M (M = iron, cobalt, nickel) supported on aluminas with different morphology and pore size as Fischer-Tropsch catalyst. The aluminas applied as support were alumina synthesized through hydrothermal process, alumina formed by pretreatment of catapal and commercial alumina which named as Ahy, Aca, and Aco respectively. Ahy has uniform morphology of nanotubes while Aca and Aco showed non-uniform morphology of particle lumps. The particle lumps of Aca were larger than those of Aco. Ahy, Aca, and Aco respectively has average pore diameter of 2.75, 2.86 and 2.9 nm. Metals were deposited on the supports by incipient-wetness impregnation method. The catalysts were characterized by XRD, H2-TPR, and H2 chemisorption. Catalyst acitivity test for Fischer-Tropsch reaction was carried out in a micro reactor at 200 °C and 1 atm, and molar ratio of H2/CO = 2:1. The metal oxide particle size increased in the order M/Aco < M/Aca < M/Ahy. The catalysts reducibility also increased according to the order M/Aco < M/Aca < M/Ahy suggesting that the larger metal oxide particles are more reducible. The number of active site was not proportional to the reducibility because during the reduction, larger metal oxide particles were converted into larger metal particles. On the other hand, the number of active sites was inversely proportional to the particle sizes. The number of active site increased in the order M/Ahy < M/Aco < M/Aca. The catalytic activity also increased in the following order M/Ahy < M/Aco < M/Aca. The activity per active site increased according to the order M/Aca < M/Aco < M/Ahy meaning that for M/Ahy, a little increase in active site will lead to a significance increase in catalytic activity. It showed that Ahy has potential for the better support