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Sample records for acids research database

  1. The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection.

    Fernández-Suárez, Xosé M; Rigden, Daniel J; Galperin, Michael Y

    2014-01-01

    The 2014 Nucleic Acids Research Database Issue includes descriptions of 58 new molecular biology databases and recent updates to 123 databases previously featured in NAR or other journals. For convenience, the issue is now divided into eight sections that reflect major subject categories. Among the highlights of this issue are six databases of the transcription factor binding sites in various organisms and updates on such popular databases as CAZy, Database of Genomic Variants (DGV), dbGaP, DrugBank, KEGG, miRBase, Pfam, Reactome, SEED, TCDB and UniProt. There is a strong block of structural databases, which includes, among others, the new RNA Bricks database, updates on PDBe, PDBsum, ArchDB, Gene3D, ModBase, Nucleic Acid Database and the recently revived iPfam database. An update on the NCBI's MMDB describes VAST+, an improved tool for protein structure comparison. Two articles highlight the development of the Structural Classification of Proteins (SCOP) database: one describes SCOPe, which automates assignment of new structures to the existing SCOP hierarchy; the other one describes the first version of SCOP2, with its more flexible approach to classifying protein structures. This issue also includes a collection of articles on bacterial taxonomy and metagenomics, which includes updates on the List of Prokaryotic Names with Standing in Nomenclature (LPSN), Ribosomal Database Project (RDP), the Silva/LTP project and several new metagenomics resources. The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been expanded to 1552 databases. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/). PMID:24316579

  2. The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection

    Rigden, Daniel J.; Fernández-Suárez, Xosé M.; Galperin, Michael Y.

    2015-01-01

    The 2016 Database Issue of Nucleic Acids Research starts with overviews of the resources provided by three major bioinformatics centers, the U.S. National Center for Biotechnology Information (NCBI), the European Bioinformatics Institute (EMBL-EBI) and Swiss Institute for Bioinformatics (SIB). Also included are descriptions of 62 new databases and updates on 95 databases that have been previously featured in NAR plus 17 previously described elsewhere. A number of papers in this issue deal wit...

  3. The Nucleic Acid Database (NDB)

    Berman, H. M.; Feng, Z.; Schneider, Bohdan; Westbrook, J.; Zardecki, C.

    Vol. F. Dordrecht : Kluwer Academic, 2001 - (Rossmann, M.; Arnold, E.), s. 657-682 Institutional research plan: CEZ:AV0Z4040901 Keywords : database * nucleic acid Subject RIV: CF - Physical ; Theoretical Chemistry

  4. Native Health Research Database

    ... APP WITH JAVASCRIPT TURNED OFF. THE NATIVE HEALTH DATABASE REQUIRES JAVASCRIPT IN ORDER TO FUNCTION. PLEASE ENTER ... To learn more about searching the Native Health Database, click here. Keywords Title Author Source of Publication ...

  5. Database Research: Achievements and Challenges

    Shan Wang; Xiao-Yong Du; Xiao-Feng Meng; Hong Chen

    2006-01-01

    Database system is the infrastructure of the modern information system. The R&D in the database system moves along by giant steps. This report presents the achievements Renmin University of China (RUC) has made in the past 25 years and at the same time addresses some of the research projects we, RUC, are currently working on. The National Natural Science Foundation of China supports and initiates most of our research projects and these successfully conducted projects have produced fruitful results.

  6. Biological Databases for Human Research

    Dong Zou; Lina Ma; Jun Yu; Zhang Zhang

    2015-01-01

    The completion of the Human Genome Project lays a foundation for systematically studying the human genome from evolutionary history to precision medicine against diseases. With the explosive growth of biological data, there is an increasing number of biological databases that have been developed in aid of human-related research. Here we present a collection of human-related biological databases and provide a mini-review by classifying them into different categories according to their data types. As human-related databases continue to grow not only in count but also in volume, challenges are ahead in big data storage, processing, exchange and curation.

  7. Database searches for qualitative research

    Evans, David

    2002-01-01

    Interest in the role of qualitative research in evidence-based health care is growing. However, the methods currently used to identify quantitative research do not translate easily to qualitative research. This paper highlights some of the difficulties during searches of electronic databases for qualitative research. These difficulties relate to the descriptive nature of the titles used in some qualitative studies, the variable information provided in abstracts, and the differences in the ind...

  8. Correlates of Access to Business Research Databases

    Gottfried, John C.

    2010-01-01

    This study examines potential correlates of business research database access through academic libraries serving top business programs in the United States. Results indicate that greater access to research databases is related to enrollment in graduate business programs, but not to overall enrollment or status as a public or private institution.…

  9. Database Support for Research in Public Administration

    Tucker, James Cory

    2005-01-01

    This study examines the extent to which databases support student and faculty research in the area of public administration. A list of journals in public administration, public policy, political science, public budgeting and finance, and other related areas was compared to the journal content list of six business databases. These databases…

  10. National Database for Autism Research (NDAR)

    U.S. Department of Health & Human Services — National Database for Autism Research (NDAR) is an extensible, scalable informatics platform for austism spectrum disorder-relevant data at all levels of biological...

  11. Research reactor records in the INIS database

    This report presents a statistical analysis of more than 13,000 records of publications concerned with research and technology in the field of research and experimental reactors which are included in the INIS Bibliographic Database for the period from 1970 to 2001. The main objectives of this bibliometric study were: to make an inventory of research reactor related records in the INIS Database; to provide statistics and scientific indicators for the INIS users, namely science managers, researchers, engineers, operators, scientific editors and publishers, decision-makers in the field of research reactors related subjects; to extract other useful information from the INIS Bibliographic Database about articles published in research reactors research and technology. (author)

  12. Indexing Research Papers in Open Access Databases

    Alexandra-Emilia Fortiş

    2009-01-01

    This paper synthesizes the actions performed in order to transform a classic scientific research journal – “Annals. Computer Science Series” – available only in printed form until 2008, into a modern e-journal with free access to the full text of the articles. For achieving this goal, the research papers have been included in various article databases, portals and library catalogs which offered a high visibility to the journal. Keywords: Open-Acces Initiative, article database, standards, me...

  13. NALDB: nucleic acid ligand database for small molecules targeting nucleic acid.

    Kumar Mishra, Subodh; Kumar, Amit

    2016-01-01

    Nucleic acid ligand database (NALDB) is a unique database that provides detailed information about the experimental data of small molecules that were reported to target several types of nucleic acid structures. NALDB is the first ligand database that contains ligand information for all type of nucleic acid. NALDB contains more than 3500 ligand entries with detailed pharmacokinetic and pharmacodynamic information such as target name, target sequence, ligand 2D/3D structure, SMILES, molecular formula, molecular weight, net-formal charge, AlogP, number of rings, number of hydrogen bond donor and acceptor, potential energy along with their Ki, Kd, IC50 values. All these details at single platform would be helpful for the development and betterment of novel ligands targeting nucleic acids that could serve as a potential target in different diseases including cancers and neurological disorders. With maximum 255 conformers for each ligand entry, our database is a multi-conformer database and can facilitate the virtual screening process. NALDB provides powerful web-based search tools that make database searching efficient and simplified using option for text as well as for structure query. NALDB also provides multi-dimensional advanced search tool which can screen the database molecules on the basis of molecular properties of ligand provided by database users. A 3D structure visualization tool has also been included for 3D structure representation of ligands. NALDB offers an inclusive pharmacological information and the structurally flexible set of small molecules with their three-dimensional conformers that can accelerate the virtual screening and other modeling processes and eventually complement the nucleic acid-based drug discovery research. NALDB can be routinely updated and freely available on bsbe.iiti.ac.in/bsbe/naldb/HOME.php. Database URL: http://bsbe.iiti.ac.in/bsbe/naldb/HOME.php. PMID:26896846

  14. Research on computer virus database management system

    Qi, Guoquan

    2011-12-01

    The growing proliferation of computer viruses becomes the lethal threat and research focus of the security of network information. While new virus is emerging, the number of viruses is growing, virus classification increasing complex. Virus naming because of agencies' capture time differences can not be unified. Although each agency has its own virus database, the communication between each other lacks, or virus information is incomplete, or a small number of sample information. This paper introduces the current construction status of the virus database at home and abroad, analyzes how to standardize and complete description of virus characteristics, and then gives the information integrity, storage security and manageable computer virus database design scheme.

  15. Databases and QSAR for Cancer Research

    Adeel Malik

    2006-01-01

    Full Text Available In this review, we take a survey of bioinformatics databases and quantitative structure-activity relationship studies reported in published literature. Databases from the most general to special cancer-related ones have been included. Most commonly used methods of structure-based analysis of molecules have been reviewed, along with some case studies where they have been used in cancer research. This article is expected to be of use for general bioinformatics researchers interested in cancer and will also provide an update to those who have been actively pursuing this field of research.

  16. PAPER REGISTRATION TO REPOSITORY FROM RESEARCHER DATABASE

    Kensuke Baba; Masao Mori

    2012-01-01

    This paper introduces a system that realizes a simultaneous registration of scholarly papers for both a researcher database and a repository. An institutional repository is a method to realize free access to research outputs. However, the number of scholarly papers archived in institutional repositories is extremely small compared to the papers practically produced by researchers. The authors considered that an obstacle to increase the number is the efforts of researchers to register their pa...

  17. Emerging multidisciplinary research across database management systems

    Nica, Anisoara; Varde, Aparna

    2011-01-01

    The database community is exploring more and more multidisciplinary avenues: Data semantics overlaps with ontology management; reasoning tasks venture into the domain of artificial intelligence; and data stream management and information retrieval shake hands, e.g., when processing Web click-streams. These new research avenues become evident, for example, in the topics that doctoral students choose for their dissertations. This paper surveys the emerging multidisciplinary research by doctoral students in database systems and related areas. It is based on the PIKM 2010, which is the 3rd Ph.D. workshop at the International Conference on Information and Knowledge Management (CIKM). The topics addressed include ontology development, data streams, natural language processing, medical databases, green energy, cloud computing, and exploratory search. In addition to core ideas from the workshop, we list some open research questions in these multidisciplinary areas.

  18. PAPER REGISTRATION TO REPOSITORY FROM RESEARCHER DATABASE

    Kensuke Baba

    2012-01-01

    Full Text Available This paper introduces a system that realizes a simultaneous registration of scholarly papers for both a researcher database and a repository. An institutional repository is a method to realize free access to research outputs. However, the number of scholarly papers archived in institutional repositories is extremely small compared to the papers practically produced by researchers. The authors considered that an obstacle to increase the number is the efforts of researchers to register their papers to institutional repositories, and they developed a system that realizes a simultaneous registration of papers to the researcher database and the institutional repository in their university. This paper introduces the main idea and the details of the implementation of the system.

  19. Emerging multidisciplinary research across database management systems

    Nica, Anisoara; Suchanek, Fabian; Varde, Aparna

    2010-01-01

    The database community is exploring more and more multidisciplinary avenues: Data semantics overlaps with ontology management; reasoning tasks venture into the domain of artificial intelligence; and data stream management and information retrieval shake hands, e.g., when processing Web click-streams. These new research avenues become evident, for example, in the topics that doctoral students choose for their dissertations. This paper surveys the emerging multidisciplinary research by doctoral...

  20. The Mining Environment Database on abandoned mines, acid mine drainage, and land reclamation

    Laurentian University Library has developed an on-line Mining Environment Database. The database provides references and abstracts to journal articles, books and government reports dealing with acid mine drainage, land reclamation, and abandoned mines. The database, created in 1988, now contains over 7,900 citations on reclamation planning, acid mine drainage, sulfide-based tailings, soil and water contamination, mine closure techniques, and other related topics dealing with mining environment studies. Subject coverage is international and focuses on hard rock mining topics. A stand-alone product for IBM-compatible computers is now available. The database is mastered on four high-density diskettes, and special search software is provided to allow full keyword searching of the database citations. Laurentian has acquired copies of all the materials cited in the database. Access to the on-line database is free of charge, with the exception of long-distance costs, and copy, delivery, or Fax charges for requested material. Suggestions for materials not found in the database and donations of pertinent research information from individuals, corporations, institutions, and government departments are welcomed. Private consulting reports (with the appropriate client approval) are especially welcomed, because this category of research literature cannot be purchased or obtained using normal methods, and is often discarded after a mine property is closed. The process of building a comprehensive research database requires a continuing partnership of information specialists and research users to develop a world class research literature database on mining environment and reclamation

  1. DATABASES in the RESEARCH of INTERNATIONAL ALLIANCES

    Susana Costa e Silva; Ferreira, Mário Pedro

    2007-01-01

    The low level of formality and the diversity of international alliances create an important challenge for researchers. Unlike mergers and acquisitions, alliances include various types of cooperation agreements between organizations and do not require formal registration. Therefore, in this field, secondary data is scarce and the few available international databases present several disadvantages. This manuscript attempts to discuss and assess options available to circumvent dif...

  2. CRITTER: A database for managing research animals

    Lees, V. Wayne; Lukey, Claire; Orr, Richard

    1993-01-01

    We describe CRITTER, a computer database program for managing research animals. We designed it especially for institutions which operate health surveillance plans, such as specific pathogen-free schemes. Because CRITTER can be used to record any type of test result in any species of animal, it can be customized to suit each institution and its management protocol. In addition to maintaining a current inventory of each individual animal and its location, the program retains historical informat...

  3. Database use in psychiatric research: An international review

    Nicola Higgins; Louise Howard

    2005-01-01

    Objective: Whilst database use for the purposes of audit is well established amongst clinicians, their research potential has yet to be fully realised. This review provides an international perspective on research using databases in psychiatry, considering the advantages and constraints of their use. Method: Large databases used in psychiatric research were identified through a systematic search of MEDLINE and EMBASE databases. The types of research conducted with these databases were then gr...

  4. The CAP Theorem Versus Databases with Relaxed ACID properties

    Frank, Lars; Ulslev Pedersen, Rasmus; Frank, Christian Havnø; Larsson, N. Jesper

    2014-01-01

    traditional ACID properties and all the CAP properties were implemented. This optimizing is especially important in mobile integrated databases, where disconnections are normal and frequent. It is also important in distributed databases like EHR (electronic Health Records) where many different hospital...... locations are involved, since the risk for disconnections increases with the number of participating locations. We use distributed integrated EHR databases as an example where our optimizing method may contribute....

  5. Construction of databases: advances and significance in clinical research.

    Long, Erping; Huang, Bingjie; Wang, Liming; Lin, Xiaoyu; Lin, Haotian

    2015-12-01

    Widely used in clinical research, the database is a new type of data management automation technology and the most efficient tool for data management. In this article, we first explain some basic concepts, such as the definition, classification, and establishment of databases. Afterward, the workflow for establishing databases, inputting data, verifying data, and managing databases is presented. Meanwhile, by discussing the application of databases in clinical research, we illuminate the important role of databases in clinical research practice. Lastly, we introduce the reanalysis of randomized controlled trials (RCTs) and cloud computing techniques, showing the most recent advancements of databases in clinical research. PMID:27215009

  6. Security Research on Engineering Database System

    2002-01-01

    Engine engineering database system is an oriented C AD applied database management system that has the capability managing distributed data. The paper discusses the security issue of the engine engineering database management system (EDBMS). Through studying and analyzing the database security, to draw a series of securi ty rules, which reach B1, level security standard. Which includes discretionary access control (DAC), mandatory access control (MAC) and audit. The EDBMS implem ents functions of DAC, ...

  7. Revolutionary Database Technology for Data Intensive Research

    2012-01-01

    The ability to explore huge digital resources assembled in data warehouses, databases and files, at unprecedented speed, is becoming the driver of progress in science. However, existing database management systems (DBMS) are far from capable of meeting the scientists' requirements. The Database Architectures group at CWI in Amsterdam cooperates with astronomers, seismologists and other domain experts to tackle this challenge by advancing all aspects of database technology. The group’s researc...

  8. Using Databases and Web Resources for Glycomics Research

    Aoki-Kinoshita, Kiyoko F

    2013-01-01

    Many databases of carbohydrate structures and related information can be found on the World Wide Web. This review covers the major carbohydrate databases that have potential utility for glycoscientists and researchers entering the glycosciences. The first half provides a brief overview of carbohydrate databases and web resources (including a history of carbohydrate databases and carbohydrate notations used in these databases), and the second half provides a guide that can be used as an index ...

  9. Aggregated Interdisciplinary Databases and the Needs of Undergraduate Researchers

    Fister, Barbara; Gilbert, Julie; Fry, Amy Ray

    2008-01-01

    After seeing growing frustration among inexperienced undergraduate researchers searching a popular aggregated interdisciplinary database, the authors questioned whether the leading interdisciplinary databases are serving undergraduates' needs. As a preliminary exploration of this question, the authors queried vendors, analyzed their marketing…

  10. RIDE: the Research Infrastructure Database for EPOS

    Bailo, Daniele; Bartoloni, Alessandro; Jeffery, Keith G.; Clemenceau, Alice; Hoffmann, Thomas L.

    2013-04-01

    The European Plate Observing System (EPOS) is a European initiative which aims to promote and make possible innovative approaches for a better understanding of the physical processes laying behind natural events and geo-science phenomena (earthquakes, volcanic eruptions, unrest episodes and tsunamis etc.) by integrating existing national and trans-national Research Infrastructures (RIs). Such integration will increase access and use of the multidisciplinary data recorded by solid Earth monitoring networks, acquired in laboratory experiments and/or produced by computational simulations. Here we present the Research Infrastructures Database for EPOS (RIDE), a database containing technical information about the different RIs declared by EPOS partners and EPOS associate partners, which will eventually compose the EPOS distributed Research Infrastructure. The main goals of RIDE are (i) to allow the EPOS RI to be organized, with interactive access and information mining available to a broad community of users and stakeholders, (ii) to have a first set of information to be stored in the EPOS catalogue, which will be used as a basis for the development of EPOS Core Services, (iii) to enable EPOS partners to revise and update the current RI information, (iv) to show the contents of the EPOS integration plan to all stakeholders, (v) to facilitate the dissemination of existing data infrastructures to different communities and to promote a discussion within the community to implement the present data infrastructures. RIDE - whose driving technology is Apache CouchDB - contains at the current status detailed information on more than 200 Research Infrastructures. It enables any user to visualize RIs and sensors on a map, to carry out statistics on the stored data and to browse through the details of any RI. Based on the content of RIDE it is now possible to estimate the potential size of the new EPOS distributed RI: EPOS is going to integrate more than 7000 sensors (seismic

  11. Database use in psychiatric research: An international review

    Nicola Higgins

    2005-03-01

    Full Text Available Objective: Whilst database use for the purposes of audit is well established amongst clinicians, their research potential has yet to be fully realised. This review provides an international perspective on research using databases in psychiatry, considering the advantages and constraints of their use. Method: Large databases used in psychiatric research were identified through a systematic search of MEDLINE and EMBASE databases. The types of research conducted with these databases were then grouped into categories for discussion. A narrative synthesis of results is presented, illustrated with examples. Results: Research identified included pharmacoepidemiology, perinatal, aetiological, suicidology and health service research. Conclusions: Databases have been used to address a range of questions in psychiatry, often by employing linkage between clinical and national administrative databases. The success of such research is not only dependent on appropriate methodology and database design, but also on clinician commitment to data entry. Further exploitation of linkage potential between databases is envisaged, alongside international development of clinical databases designed with the purpose of research in mind.

  12. Czech multicenter research database of severe COPD

    Novotna B

    2014-11-01

    Full Text Available Barbora Novotna,1 Vladimir Koblizek,1 Jaromir Zatloukal,2 Marek Plutinsky,3 Karel Hejduk,4 Zuzana Zbozinkova,4 Jiri Jarkovsky,4 Ondrej Sobotik,5 Tomas Dvorak,6 Petr Safranek71Department of Pneumology, University Hospital Hradec Kralove, Charles University in Prague, Faculty of Medicine in Hradec Kralove, Hradec Kralove, 2Department of Pulmonology, University Hospital, Palacky University, Olomouc, 3Department of Pulmonology, University Hospital, Masaryk University, Brno, 4Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, 5Department of Pulmonology, University Hospital Motol, Charles University, Praha, 6Department of Pulmonology, Hospital Bulovka, Praha, 7Department of Pulmonology, University Hospital, Charles University, Plzen, the Czech RepublicPurpose: Chronic obstructive pulmonary disease (COPD has been recognized as a heterogeneous, multiple organ system-affecting disorder. The Global Initiative for Chronic Obstructive Lung Disease (GOLD places emphasis on symptom and exacerbation management. The aim of this study is examine the course of COPD and its impact on morbidity and all-cause mortality of patients, with respect to individual phenotypes and GOLD categories. This study will also evaluate COPD real-life patient care in the Czech Republic.Patients and methods: The Czech Multicentre Research Database of COPD is projected to last for 5 years, with the aim of enrolling 1,000 patients. This is a multicenter, observational, and prospective study of patients with severe COPD (post-bronchodilator forced expiratory volume in 1 second ≤60%. Every consecutive patient, who fulfils the inclusion criteria, is asked to participate in the study. Patient recruitment is done on the basis of signed informed consent. The study was approved by the Multicentre Ethical Committee in Brno, Czech Republic.Results: The objective of this paper was to outline the methodology of this study.Conclusion: The establishment of the

  13. Arabidopsis Hormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis

    Peng, Zhi-Yu; Zhou, Xin; Li, Linchuan; Yu, Xiangchun; Li, Hongjiang; Jiang, Zhiqiang; Cao, Guangyu; Bai, Mingyi; Wang, Xingchun; Jiang, Caifu; Lu, Haibin; Hou, Xianhui; Qu, Lijia; Wang, Zhiyong; Zuo, Jianru

    2008-01-01

    Plant hormones are small organic molecules that influence almost every aspect of plant growth and development. Genetic and molecular studies have revealed a large number of genes that are involved in responses to numerous plant hormones, including auxin, gibberellin, cytokinin, abscisic acid, ethylene, jasmonic acid, salicylic acid, and brassinosteroid. Here, we develop an Arabidopsis hormone database, which aims to provide a systematic and comprehensive view of genes participating in plant h...

  14. Databases in the 3rd Millennium: Trends and Research Directions

    Jaroslav Pokorny

    2010-04-01

    Full Text Available A database approach to data of arbitrary types has shown that the architecture of a universal database machine is restricting in a number of cases. There appear special-purpose data servers using now types of hardware devices. Data is moving toward the user, who exploits mobile devices equipped with database functionality. The goal of the paper is to present new trends in databases, particularly in their architectures and to show on cloud computing, data streams, mobile and embedded databases, and databases supporting Web.2.0 some new ideas and possibilities of solution of associated problems. The other goal of the paper is also to point out on actual problems associated with database research.

  15. Privacy and Data-Based Research

    Ori Heffetz; Katrina Ligett

    2014-01-01

    What can we, as users of microdata, formally guarantee to the individuals (or firms) in our dataset, regarding their privacy? We retell a few stories, well-known in data-privacy circles, of failed anonymization attempts in publicly released datasets. We then provide a mostly informal introduction to several ideas from the literature on differential privacy, an active literature in computer science that studies formal approaches to preserving the privacy of individuals in statistical databases...

  16. Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

    Surati, Mosmi; Robinson, Matthew; Nandi, Suvobroto; Faoro, Leonardo; Demchuk, Carley; Kanteti, Rajani; Ferguson, Benjamin; Gangadhar, Tara; Hensing, Thomas; Hasina, Rifat; Husain, Aliya; Ferguson, Mark; Karrison, Theodore; Salgia, Ravi

    2011-01-01

    The Thoracic Oncology Program Database Project was created to serve as a comprehensive, verified, and accessible repository for well-annotated cancer specimens and clinical data to be available to researchers within the Thoracic Oncology Research Program. This database also captures a large volume of genomic and proteomic data obtained from various tumor tissue studies. A team of clinical and basic science researchers, a biostatistician, and a bioinformatics expert was convened to design the ...

  17. Business Faculty Research: Satisfaction with the Web versus Library Databases

    Dewald, Nancy H.; Silvius, Matthew A.

    2005-01-01

    Business faculty members teaching at undergraduate campuses of the Pennsylvania State University were surveyed in order to assess their satisfaction with free Web sources and with subscription databases for their professional research. Although satisfaction with the Web's ease of use was higher than that for databases, overall satisfaction for…

  18. The Vocational Guidance Research Database: A Scientometric Approach

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the use of…

  19. Research on methods of designing and building digital seabed database

    Su Tianyun; Liu Baohua; Zhai Shikui; Liang Ruicai; Zheng Yanpeng; Fu Qiang

    2007-01-01

    With a review of the recent development in digitalization and application of seabed data , this paper systematically proposed methods for integrating seabed data by analyzing its feature based on ORACLE database management system and advanced techniques of spatial data management. We did research on storage structure of seabed data, distributed- integrated database system, standardized spatial database and seabed metadata management system in order to effectively manage and use these seabed information in practical application . Finally , we applied the methods researched and proposed in this paper to build the Bohai Sea engineering geology database that stores engineering geology data and other seabed information from the Bohai Sea area . As a result , the Bohai Sea engineering geology database can effectively integrate huge amount of distributed and complicated seabed data to meet the practical requisition of Bohai Sea engineering geology environment exploration and exploitation.

  20. Research reactor records in the INIS Database - A bibliometric study

    This report presents a statistical analysis of more than 13,000 records of publications concerned with research and technology in the field of research and/or experimental reactors which are included in the INIS Bibliographic Database for the period from 1970 to 2002. The main objectives of this bibliometric study were: to make an inventory of research reactor related records in the INIS Database; to provide statistics and scientific indicators for the INIS users, namely science managers, researchers, engineers, operators, scientific editors and publishers, decision-makers in the field of research reactors related subjects; to extract other useful information from the INIS Bibliographic Database about articles published in research reactors research and technology. Special attention is devoted to publications related to fuel management and RERTR issues. The quantitative data in this report are obtained for various properties of relevant INIS records such as year of publication, secondary subject categories, countries of publication, language, publication types, literary types, etc. (author)

  1. Databases for multilevel biophysiology research available at Physiome.jp

    Yoshiyuki eAsai

    2015-09-01

    Full Text Available Physiome.jp (http://physiome.jp is a portal site inaugurated in 2007 to support model-based research in physiome and systems biology. At Physiome.jp, several tools and databases are available to support construction of physiological, multi-hierarchical, large-scale models. There are three databases in Physiome.jp, housing mathematical models, morphological data, and time-series data. In late 2013, the site was fully renovated, and in May 2015, new functions were implemented to provide information infrastructure to support collaborative activities for developing models and performing simulations within the database framework. This article describes updates to the databases implemented since 2013, including cooperation among the three databases, interactive model browsing, user management, version management of models, management of parameter sets, and interoperability with applications.

  2. Scientific research into training and database

    Lanfranco

    2013-12-01

    Full Text Available School and university, privileged places of experience and exercise of the mind, with a quality organization pursuing competence and merit, urged to pressure by the data and materials research, as well as under the pressure of the network.

  3. FRED-MD: A Monthly Database for Macroeconomic Research

    Michael W. McCracken; Ng, Serena

    2015-01-01

    This paper describes a large, monthly frequency, macroeconomic database with the goal of establishing a convenient starting point for empirical analysis that requires "big data." The dataset mimics the coverage of those already used in the literature but has three appealing features. First, it is designed to be updated monthly using the FRED database. Second, it will be publicly accessible, facilitating comparison of related research and replication of empirical work. Third, it will relieve r...

  4. Amino Acid Sequence - KOME | LSDB Archive [Life Science Database Archive metadata

    Full Text Available [ Credits ] BLAST Search Image Search Home About Archive Update History Contact us ...CE Amino acid sequence Joomla SEF URLs by Artio About This Database Database Description Download License Update History

  5. DANBIO-powerful research database and electronic patient record

    Hetland, Merete Lund

    2011-01-01

    an overview of the research outcome and presents the cohorts of RA patients. The registry, which is approved as a national quality registry, includes patients with RA, PsA and AS, who are followed longitudinally. Data are captured electronically from the source (patients and health personnel). The IT...... an electronic patient 'chronicle' in routine care, and at the same time provides a powerful research database.......The nationwide DANBIO registry has been designed to capture operational clinical data as part of routine clinical care. At the same time, it provides a powerful research database. This article reviews the DANBIO registry with focus on problems and solutions of design, funding and linkage, provides...

  6. Fedora Content Modelling for Improved Services for Research Databases

    Elbæk, Mikael Karstensen; Heller, Alfred; Pedersen, Gert Schmeltz

    A re-implementation of the research database of the Technical University of Denmark, DTU, is based on Fedora. The backbone consists of content models for primary and secondary entities and their relationships, giving flexible and powerful extraction capabilities for interoperability and reporting....... By adopting such an abstract data model, the platform enables new and improved services for researchers, librarians and administrators....

  7. Fusion research and technology records in INIS database

    This article is a summary of a survey study ''''A survey on publications in Fusion Research and Technology. Science and Technology Indicators in Fusion R and T'''' by the same author on Fusion R and T records in the International Nuclear Information System (INIS) bibliographic database. In that study, for the first time, all scientometric and bibliometric information contained in a bibliographic database, using INIS records, is analyzed and quantified, specific to a selected field of science and technology. A variety of new science and technology indicators which can be used for evaluating research and development activities is also presented in that study that study

  8. A lexical database tool for quantitative phonological research

    Bird, S D

    1999-01-01

    A lexical database tool tailored for phonological research is described. Database fields include transcriptions, glosses and hyperlinks to speech files. Database queries are expressed using HTML forms, and these permit regular expression search on any combination of fields. Regular expressions are passed directly to a Perl CGI program, enabling the full flexibility of Perl extended regular expressions. The regular expression notation is extended to better support phonological searches, such as search for minimal pairs. Search results are presented in the form of HTML or LaTeX tables, where each cell is either a number (representing frequency) or a designated subset of the fields. Tables have up to four dimensions, with an elegant system for specifying which fragments of which fields should be used for the row/column labels. The tool offers several advantages over traditional methods of analysis: (i) it supports a quantitative method of doing phonological research; (ii) it gives universal access to the same se...

  9. Current research status, databases and application of single nucleotide polymorphism.

    Javed, R; Mukesh

    2010-07-01

    Single Nucleotide Polymorphisms (SNPs) are the most frequent form of DNA variation in the genome. SNPs are genetic markers which are bi-allelic in nature and grow at a very fast rate. Current genomic databases contain information on several million SNPs. More than 6 million SNPs have been identified and the information is publicly available through the efforts of the SNP Consortium and others data bases. The NCBI plays a major role in facillating the identification and cataloging of SNPs through creation and maintenance of the public SNP database (dbSNP) by the biomedical community worldwide and stimulate many areas of biological research including the identification of the genetic components of disease. In this review article, we are compiling the existing SNP databases, research status and their application. PMID:21717869

  10. GiSAO.db: a database for ageing research

    Grillari Johannes

    2011-05-01

    Full Text Available Abstract Background Age-related gene expression patterns of Homo sapiens as well as of model organisms such as Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster are a basis for understanding the genetic mechanisms of ageing. For an effective analysis and interpretation of expression profiles it is necessary to store and manage huge amounts of data in an organized way, so that these data can be accessed and processed easily. Description GiSAO.db (Genes involved in senescence, apoptosis and oxidative stress database is a web-based database system for storing and retrieving ageing-related experimental data. Expression data of genes and miRNAs, annotation data like gene identifiers and GO terms, orthologs data and data of follow-up experiments are stored in the database. A user-friendly web application provides access to the stored data. KEGG pathways were incorporated and links to external databases augment the information in GiSAO.db. Search functions facilitate retrieval of data which can also be exported for further processing. Conclusions We have developed a centralized database that is very well suited for the management of data for ageing research. The database can be accessed at https://gisao.genome.tugraz.at and all the stored data can be viewed with a guest account.

  11. Gas Hydrate Research Database and Web Dissemination Channel

    Micheal Frenkel; Kenneth Kroenlein; V Diky; R.D. Chirico; A. Kazakow; C.D. Muzny; M. Frenkel

    2009-09-30

    To facilitate advances in application of technologies pertaining to gas hydrates, a United States database containing experimentally-derived information about those materials was developed. The Clathrate Hydrate Physical Property Database (NIST Standard Reference Database {number_sign} 156) was developed by the TRC Group at NIST in Boulder, Colorado paralleling a highly-successful database of thermodynamic properties of molecular pure compounds and their mixtures and in association with an international effort on the part of CODATA to aid in international data sharing. Development and population of this database relied on the development of three components of information-processing infrastructure: (1) guided data capture (GDC) software designed to convert data and metadata into a well-organized, electronic format, (2) a relational data storage facility to accommodate all types of numerical and metadata within the scope of the project, and (3) a gas hydrate markup language (GHML) developed to standardize data communications between 'data producers' and 'data users'. Having developed the appropriate data storage and communication technologies, a web-based interface for both the new Clathrate Hydrate Physical Property Database, as well as Scientific Results from the Mallik 2002 Gas Hydrate Production Research Well Program was developed and deployed at http://gashydrates.nist.gov.

  12. A relational database application in support of integrated neuroscience research.

    Rudowsky, Ira; Kulyba, Olga; Kunin, Mikhail; Ogarodnikov, Dmitri; Raphan, Theodore

    2004-12-01

    The development of relational databases has significantly improved the performance of storage, search, and retrieval functions and has made it possible for applications that perform real-time data acquisition and analysis to interact with these types of databases. The purpose of this research was to develop a user interface for interaction between a data acquisition and analysis application and a relational database using the Oracle9i system. The overall system was designed to have an indexing capability that threads into the data acquisition and analysis programs. Tables were designed and relations within the database for indexing the files and information contained within the files were established. The system provides retrieval capabilities over a broad range of media, including analog, event, and video data types. The system's ability to interact with a data capturing program at the time of the experiment to create both multimedia files as well as the meta-data entries in the relational database avoids manual entries in the database and ensures data integrity and completeness for further interaction with the data by analysis applications. PMID:15657974

  13. Arabidopsis Hormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis.

    Peng, Zhi-yu; Zhou, Xin; Li, Linchuan; Yu, Xiangchun; Li, Hongjiang; Jiang, Zhiqiang; Cao, Guangyu; Bai, Mingyi; Wang, Xingchun; Jiang, Caifu; Lu, Haibin; Hou, Xianhui; Qu, Lijia; Wang, Zhiyong; Zuo, Jianru; Fu, Xiangdong; Su, Zhen; Li, Songgang; Guo, Hongwei

    2009-01-01

    Plant hormones are small organic molecules that influence almost every aspect of plant growth and development. Genetic and molecular studies have revealed a large number of genes that are involved in responses to numerous plant hormones, including auxin, gibberellin, cytokinin, abscisic acid, ethylene, jasmonic acid, salicylic acid, and brassinosteroid. Here, we develop an Arabidopsis hormone database, which aims to provide a systematic and comprehensive view of genes participating in plant hormonal regulation, as well as morphological phenotypes controlled by plant hormones. Based on data from mutant studies, transgenic analysis and gene ontology (GO) annotation, we have identified a total of 1026 genes in the Arabidopsis genome that participate in plant hormone functions. Meanwhile, a phenotype ontology is developed to precisely describe myriad hormone-regulated morphological processes with standardized vocabularies. A web interface (http://ahd.cbi.pku.edu.cn) would allow users to quickly get access to information about these hormone-related genes, including sequences, functional category, mutant information, phenotypic description, microarray data and linked publications. Several applications of this database in studying plant hormonal regulation and hormone cross-talk will be presented and discussed. PMID:19015126

  14. Key-linked on-line databases for clinical research.

    Müller, Thomas H

    2012-01-01

    Separating patient identification data from clinical data and/or information about biomaterial samples is an effective data protection measure, especially in clinical research employing "on-line", i.e., web-based, data capture. In this paper, we show that this specialised technique can be generalised into a network architecture of interconnected on-line databases potentially serving a variety of purposes. The basic idea of this approach consists of maintaining logical links, i.e., common record keys, between corresponding data structures in pairs of databases while keeping the actual key values hidden from clients. For client systems, simultaneous access to corresponding records is mediated by temporary access tokens. At the relational level, these links are represented by arbitrary unique record keys common to both databases. This architecture allows for integration of related data in different databases without replicating or permanently sharing this data in one place. Each participating on-line database can determine the degree of integration by specifying linkage keys only for those data structures that may be logically connected to other data. Logical links can de designed for specific use cases. In addition, each database controls user access by enforcing its own authorisation scheme. Another advantage is that individual database owners retain considerable leeway in adapting to changing local requirements without compromising the integration into the network. Beyond protecting individual subject identification data, this architecture permits splitting a cooperatively used data pool to achieve many kinds of objectives. Application examples could be clinical registries needing subject contact information for follow-up, biomaterial banks with or without genetic information, and automatic or assisted integration of data from electronic medical records into research data. PMID:22874246

  15. About the database of Meteorological and Environmental Research

    2011-01-01

    The journal of Meteorological and Environmental Research [ISSN: 2152 -3940]has been included and stored by four fa-mous databases: CAS,CABI,CSA and CNKI.CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  16. Nephele:Electronic Database of Materials Research of Paintings

    Zitová, Barbara; Beneš, Miroslav; Hradil, David; Hradilová, J.

    Belgie : Ename Center for Public Archaeology and Heritage Presentation, 2007. s. 79-79. [The 3rd Annual Ename International Colloquium. 21.03.07-24.03.07, Gent] R&D Projects: GA MŠk(CZ) 1M0572 Institutional research plan: CEZ:AV0Z10750506 Keywords : image database * image retrieval Subject RIV: JC - Computer Hardware ; Software

  17. Geoscience research databases for coastal Alabama ecosystem management

    Hummell, Richard L.

    1995-01-01

    Effective management of complex coastal ecosystems necessitates access to scientific knowledge that can be acquired through a multidisciplinary approach involving Federal and State scientists that take advantage of agency expertise and resources for the benefit of all participants working toward a set of common research and management goals. Cooperative geostatic investigations have led toward building databases of fundamental scientific knowledge that can be utilized to manage coastal Alabama's natural and future development. These databases have been used to assess the occurrence and economic potential of hard mineral resources in the Alabama EFZ, and to support oil spill contingency planning and environmental analysis for coastal Alabama.

  18. RepSeq – A database of amino acid repeats present in lower eukaryotic pathogens

    Smith Deborah F

    2007-04-01

    Full Text Available Abstract Background Amino acid repeat-containing proteins have a broad range of functions and their identification is of relevance to many experimental biologists. In human-infective protozoan parasites (such as the Kinetoplastid and Plasmodium species, they are implicated in immune evasion and have been shown to influence virulence and pathogenicity. RepSeq http://repseq.gugbe.com is a new database of amino acid repeat-containing proteins found in lower eukaryotic pathogens. The RepSeq database is accessed via a web-based application which also provides links to related online tools and databases for further analyses. Results The RepSeq algorithm typically identifies more than 98% of repeat-containing proteins and is capable of identifying both perfect and mismatch repeats. The proportion of proteins that contain repeat elements varies greatly between different families and even species (3–35% of the total protein content. The most common motif type is the Sequence Repeat Region (SRR – a repeated motif containing multiple different amino acid types. Proteins containing Single Amino Acid Repeats (SAARs and Di-Peptide Repeats (DPRs typically account for 0.5–1.0% of the total protein number. Notable exceptions are P. falciparum and D. discoideum, in which 33.67% and 34.28% respectively of the predicted proteomes consist of repeat-containing proteins. These numbers are due to large insertions of low complexity single and multi-codon repeat regions. Conclusion The RepSeq database provides a repository for repeat-containing proteins found in parasitic protozoa. The database allows for both individual and cross-species proteome analyses and also allows users to upload sequences of interest for analysis by the RepSeq algorithm. Identification of repeat-containing proteins provides researchers with a defined subset of proteins which can be analysed by expression profiling and functional characterisation, thereby facilitating study of pathogenicity

  19. Databases

    National Aeronautics and Space Administration — The databases of computational and experimental data from the first Aeroelastic Prediction Workshop are located here. The databases file names tell their contents...

  20. Databases

    Kunte, P.D.

    Information on bibliographic as well as numeric/textual databases relevant to coastal geomorphology has been included in a tabular form. Databases cover a broad spectrum of related subjects like coastal environment and population aspects, coastline...

  1. Concierge: Personal database software for managing digital research resources

    Hiroyuki Sakai

    2007-11-01

    Full Text Available This article introduces a desktop application, named Concierge, for managing personal digital research resources. Using simple operations, it enables storage of various types of files and indexes them based on content descriptions. A key feature of the software is a high level of extensibility. By installing optional plug-ins, users can customize and extend the usability of the software based on their needs. In this paper, we also introduce a few optional plug-ins: literaturemanagement, electronic laboratory notebook, and XooNlps client plug-ins. XooNIps is a content management system developed to share digital research resources among neuroscience communities. It has been adopted as the standard database system in Japanese neuroinformatics projects. Concierge, therefore, offers comprehensive support from management of personal digital research resources to their sharing in open-access neuroinformatics databases such as XooNIps. This interaction between personal and open-access neuroinformatics databases is expected to enhance the dissemination of digital research resources. Concierge is developed as an open source project; Mac OS X and Windows XP versions have been released at the official site (http://concierge.sourceforge.jp.

  2. [Benefits of large healthcare databases for drug risk research].

    Garbe, Edeltraut; Pigeot, Iris

    2015-08-01

    Large electronic healthcare databases have become an important worldwide data resource for drug safety research after approval. Signal generation methods and drug safety studies based on these data facilitate the prospective monitoring of drug safety after approval, as has been recently required by EU law and the German Medicines Act. Despite its large size, a single healthcare database may include insufficient patients for the study of a very small number of drug-exposed patients or the investigation of very rare drug risks. For that reason, in the United States, efforts have been made to work on models that provide the linkage of data from different electronic healthcare databases for monitoring the safety of medicines after authorization in (i) the Sentinel Initiative and (ii) the Observational Medical Outcomes Partnership (OMOP). In July 2014, the pilot project Mini-Sentinel included a total of 178 million people from 18 different US databases. The merging of the data is based on a distributed data network with a common data model. In the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCEPP) there has been no comparable merging of data from different databases; however, first experiences have been gained in various EU drug safety projects. In Germany, the data of the statutory health insurance providers constitute the most important resource for establishing a large healthcare database. Their use for this purpose has so far been severely restricted by the Code of Social Law (Section 75, Book 10). Therefore, a reform of this section is absolutely necessary. PMID:26092163

  3. Systematically retrieving research – a case study evaluating seven databases.

    Taylor, B.J.; Wylie, E.; Dempster, Martin; Donnelly, Michael

    2007-01-01

    Objective: Developing the scientific underpinnings of social welfare requires effective and efficient methods of retrieving relevant items from the increasing volume of research. Method: We compared seven databases by running the nearest equivalent search on each. The search topic was chosen for relevance to social work practice with older people. Results: Highest sensitivity was achieved by Medline (52%), Social Sciences Citation Index (46%) and Cumulative Index of Nursing and Allied Health ...

  4. About the Database of Meteorological and Environmental Research

    2012-01-01

    The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by five famous databases:CAS,CABI,CSA,EBSCO and CNKI. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive source for chemical information. Centre for Agriculture and Bioscience International(CABI) is a not-for-profit international

  5. About the Database of Meteorological and Environmental Research

    2012-01-01

    正The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by five famous databases:CAS,CABI,CSA,EBSCO and CNKI. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive source for chemical information. Centre for Agriculture and Bioscience International(CABI) is a not-for-profit international

  6. XML Database Researching%XML数据库技术研究

    秦杰; 杨树强; 窦文华

    2003-01-01

    XML database is a new database technology. This paper gives an overview about the last research aboutXML database and its related productions,then comparing XML database with traditional RDBMS. We analyze andpoint out some weaknesses about XML database,and give out our viewpoint.

  7. BAO Plate Archive Project: Digitization, Electronic Database and Research Programmes

    Mickaelian, A. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Farmanyan, S. V.; Gigoyan, K. S.; Gyulzadyan, M. V.; Khachatryan, K. G.; Knyazyan, A. V.; Kostandyan, G. R.; Mikayelyan, G. A.; Nikoghosyan, E. H.; Paronyan, G. M.; Vardanyan, A. V.

    2016-06-01

    The most important part of the astronomical observational heritage are astronomical plate archives created on the basis of numerous observations at many observatories. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,000 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt type and other smaller telescopes during 1947-1991. In 2002-2005, the famous Markarian Survey (also called First Byurakan Survey, FBS) 1874 plates were digitized and the Digitized FBS (DFBS) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. A large project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage was started in 2015. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 11 astronomers and 2 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database will be used to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects, mainly including high proper motion stars, variable objects and Solar System bodies.

  8. Databases

    Nick Ryan

    2004-01-01

    Full Text Available Databases are deeply embedded in archaeology, underpinning and supporting many aspects of the subject. However, as well as providing a means for storing, retrieving and modifying data, databases themselves must be a result of a detailed analysis and design process. This article looks at this process, and shows how the characteristics of data models affect the process of database design and implementation. The impact of the Internet on the development of databases is examined, and the article concludes with a discussion of a range of issues associated with the recording and management of archaeological data.

  9. GENAS: a database system for nucleic acid sequence analysis.

    Kuhara, S; Matsuo, F; Futamura, S; A. Fujita; Shinohara, T.; Takagi, T.; Sakaki, Y

    1984-01-01

    A database system, named GENAS (GENe Analyzing System), for computer analysis of sequence was constructed using Adbis which is a relational database management system (1). GENAS enables us to retrieve any sequence data from EMBL nucleotide sequence data library (2) and readily to analyze them (if necessary, together with private data) by various application programs in a interactive manner. Analysis of structure of replication origin of replicons was demonstrated using this system.

  10. DANBIO-powerful research database and electronic patient record

    Hetland, Merete Lund

    2011-01-01

    The nationwide DANBIO registry has been designed to capture operational clinical data as part of routine clinical care. At the same time, it provides a powerful research database. This article reviews the DANBIO registry with focus on problems and solutions of design, funding and linkage, provides...... an overview of the research outcome and presents the cohorts of RA patients. The registry, which is approved as a national quality registry, includes patients with RA, PsA and AS, who are followed longitudinally. Data are captured electronically from the source (patients and health personnel). The IT...... platform is based on open-source software. Via a unique personal identification code, linkage with various national registers is possible for research purposes. Since the year 2000, more than 10,000 patients have been included. The main focus of research has been on treatment efficacy and drug survival...

  11. The FoodCast Research Image Database (FRIDa

    Francesco eForoni

    2013-03-01

    Full Text Available In recent years we have witnessed to an increasing interest in food processing and eating behaviors. This is probably due to several reasons. The biological relevance of food choices, the complexity of the food-rich environment in which we presently live (making food-intake regulation difficult, and the increasing health care cost due to illness associated with food (food hazards, food contamination, and aberrant food-intake. Despite the importance of the issues and the relevance of this research, comprehensive and validated databases of stimuli are rather limited, outdated, or not available for noncommercial purposes to independent researchers who aim at developing their own research program. The FoodCast Research Image Database (FRIDa we present here is comprised of 877 images from eight different categories: natural-food (e.g., strawberry, transformed-food (e.g., French fries, rotten-food (e.g., moldy banana, natural-nonfood items (e.g., pinecone, artificial food-related objects (e.g., teacup, artificial objects (e.g., guitar, animals (e.g., camel, and scenes (e.g., airport. FRIDa has been validated on a sample of healthy participants (N=73 on standard variables (e.g., valence, familiarity etc. as well as on other variables specifically related to food items (e.g., perceived calorie content; it also includes data on the visual features of the stimuli (e.g., brightness, high frequency power etc.. FRIDa is a well-controlled, flexible, validated, and freely available (http://foodcast.sissa.it/neuroscience/ tool for researchers in a wide range of academic fields and industry.

  12. Databases in the 3rd Millennium: Trends and Research Directions

    Jaroslav Pokorny

    2010-01-01

    A database approach to data of arbitrary types has shown that the architecture of a universal database machine is restricting in a number of cases. There appear special-purpose data servers using now types of hardware devices. Data is moving toward the user, who exploits mobile devices equipped with database functionality. The goal of the paper is to present new trends in databases, particularly in their architectures and to show on cloud computing, data streams, mobile and embedded databases...

  13. Managing Consistency Anomalies in Distributed Integrated Databases with Relaxed ACID Properties

    Frank, Lars; Ulslev Pedersen, Rasmus

    2014-01-01

    In central databases the consistency of data is normally implemented by using the ACID (Atomicity, Consistency, Isolation and Durability) properties of a DBMS (Data Base Management System). This is not possible if distributed and/or mobile databases are involved and the availability of data also...... been committed and completed, the execution has the consistency property. The above definition of the consistency property is not useful in distributed databases with relaxed ACID properties because such a database is almost always inconsistent. In the following, we will use the concept Consistency...... distributed consistency property. We will also illustrate how to use the countermeasures against the consistency anomalies in ERP systems integrated with heterogeneous E-commerce systems and the databases of mobile salesman ERP modules. The methods described in this paper may be used in so called CAP...

  14. Geo-scientific database for research and development purposes

    Document available in extended abstract form only. The Research and Development Division must manage, secure and reliable manner, a large number of data from scientific disciplines and diverse means of acquisition (observations, measurements, experiments, etc.). This management is particularly important for the Underground research Laboratory, the source of many recording continuous measurements. Thus, from its conception, Andra has implemented two management tools of scientific information, the 'Acquisition System and Data Management' [SAGD] and GEO database with its associated applications. Beyond its own needs, Andra wants to share its achievements with the scientific community, and it therefore provides the data stored in its databases or samples of rock or water when they are available. Acquisition and Data Management (SAGD) This system manages data from sensors installed at several sites. Some sites are on the surface (piezometric, atmospheric and environmental stations), the other are in the Underground Research Laboratory. This system also incorporates data from experiments in which Andra participates in Mont Terri Laboratory in Switzerland. S.A.G.D fulfils these objectives by: - Make available in real time on a single system, with scientists from Andra but also different partners or providers who need it, all experimental data from measurement points - Displaying the recorded data on temporal windows and specific time step, - Allowing remote control of the experimentations, - Ensuring the traceability of all recorded information, - Ensuring data storage in a data base. S.A.G.D has been deployed in the first experimental drift at -445 m in November 2004. It was subsequently extended to the underground Mont Terri laboratory in Switzerland in 2005, to the entire surface logging network of the Meuse / Haute-Marne Center in 2008 and to the environmental network in 2011. All information is acquired, stored and manage by a software called Geoscope. This software

  15. Knowledge map of artemisinin research in SCI and Medline database

    Qiang Yao , Jing Chen , Peng-Hui Lyu , Shi-Jing Zhang , Fei-Cheng Ma & Jian-Guo Fang

    2012-12-01

    Full Text Available Background & objectives: Artemisinin was first extracted from the herb Artemisia annua which has been used formany centuries in Chinese traditional medicine as a treatment for fever and malaria. It has been given the 2011Lasker-DeBakey clinical medical research award. In this paper, knowledge map of artemisinin research wasdrawn to provide some information for global researchers interested in artemisinin and its relevant references.Methods: In this work, bibliometric analysis and knowledge visualization technology were applied to evaluateglobal scientific production and developing trend of artemisinin research through Science Citation Index (SCIpapers and Medline papers with online version published as following aspects: publication outputs, subjectcategories, journals, countries, international collaboration, citations, authorship and co-authorship, author keywords and co-words analysis. The Thomson Data Analyzer (TDA, Netdraw and Aureka software were employedto analyze the SCI as well as Medline papers data for knowledge mapping.Results: Global literature of artemisinin research has increased rapidly over the past 30 years and has boosted inrecent years. Seen from the statistical study in many aspects, Pharmacology & Pharmacy, and Chemistry are stillthe main subjects of artemisinin research with parasitology and tropical medicine increasing quickly. MalariaJournal and American Journal of Tropical Medicine are top productive journals both in SCI and Medline databases.Quantity and quality of papers in US are in a leading position, although papers quantity and active degree indeveloping countries such as P.R. China, Thailand and India are relatively high, the quality of papers from thesecountries needs to be improved. New emerging key words and co-words remind us that mechanism of action,pharmacokinetics, artemisinin-based alternatives, etc. are the future trends of artemisinin research.Conclusion: Through bibliometric analysis the development

  16. TB database: an integrated platform for tuberculosis research.

    Reddy, T B K; Riley, Robert; Wymore, Farrell; Montgomery, Phillip; DeCaprio, Dave; Engels, Reinhard; Gellesch, Marcel; Hubble, Jeremy; Jen, Dennis; Jin, Heng; Koehrsen, Michael; Larson, Lisa; Mao, Maria; Nitzberg, Michael; Sisk, Peter; Stolte, Christian; Weiner, Brian; White, Jared; Zachariah, Zachariah K; Sherlock, Gavin; Galagan, James E; Ball, Catherine A; Schoolnik, Gary K

    2009-01-01

    The effective control of tuberculosis (TB) has been thwarted by the need for prolonged, complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the absence of biomarkers of clinical status. The promise of the genomics era for TB control is substantial, but has been hindered by the lack of a central repository that collects and integrates genomic and experimental data about this organism in a way that can be readily accessed and analyzed. The Tuberculosis Database (TBDB) is an integrated database providing access to TB genomic data and resources, relevant to the discovery and development of TB drugs, vaccines and biomarkers. The current release of TBDB houses genome sequence data and annotations for 28 different Mycobacterium tuberculosis strains and related bacteria. TBDB stores pre- and post-publication gene-expression data from M. tuberculosis and its close relatives. TBDB currently hosts data for nearly 1500 public tuberculosis microarrays and 260 arrays for Streptomyces. In addition, TBDB provides access to a suite of comparative genomics and microarray analysis software. By bringing together M. tuberculosis genome annotation and gene-expression data with a suite of analysis tools, TBDB (http://www.tbdb.org/) provides a unique discovery platform for TB research. PMID:18835847

  17. The GUDMAP database--an online resource for genitourinary research.

    Harding, Simon D; Armit, Chris; Armstrong, Jane; Brennan, Jane; Cheng, Ying; Haggarty, Bernard; Houghton, Derek; Lloyd-MacGilp, Sue; Pi, Xingjun; Roochun, Yogmatee; Sharghi, Mehran; Tindal, Christopher; McMahon, Andrew P; Gottesman, Brian; Little, Melissa H; Georgas, Kylie; Aronow, Bruce J; Potter, S Steven; Brunskill, Eric W; Southard-Smith, E Michelle; Mendelsohn, Cathy; Baldock, Richard A; Davies, Jamie A; Davidson, Duncan

    2011-07-01

    The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research. PMID:21652655

  18. The GUDMAP database – an online resource for genitourinary research

    Harding, Simon D.; Armit, Chris; Armstrong, Jane; Brennan, Jane; Cheng, Ying; Haggarty, Bernard; Houghton, Derek; Lloyd-MacGilp, Sue; Pi, Xingjun; Roochun, Yogmatee; Sharghi, Mehran; Tindal, Christopher; McMahon, Andrew P.; Gottesman, Brian; Little, Melissa H.; Georgas, Kylie; Aronow, Bruce J.; Potter, S. Steven; Brunskill, Eric W.; Southard-Smith, E. Michelle; Mendelsohn, Cathy; Baldock, Richard A.; Davies, Jamie A.; Davidson, Duncan

    2011-01-01

    The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research. PMID:21652655

  19. University Real Estate Development Database: A Database-Driven Internet Research Tool

    Wiewel, Wim; Kunst, Kara

    2008-01-01

    The University Real Estate Development Database is an Internet resource developed by the University of Baltimore for the Lincoln Institute of Land Policy, containing over six hundred cases of university expansion outside of traditional campus boundaries. The University Real Estate Development database is a searchable collection of real estate…

  20. Research Note on the Energy Infrastructure Attack Database (EIAD

    Jennifer Giroux

    2013-12-01

    Full Text Available The January 2013 attack on the In Amenas natural gas facility drew international attention. However this attack is part of a portrait of energy infrastructure targeting by non-state actors that spans the globe. Data drawn from the Energy Infrastructure Attack Database (EIAD shows that in the last decade there were, on average, nearly 400 annual attacks carried out by armed non-state actors on energy infrastructure worldwide, a figure that was well under 200 prior to 1999. This data reveals a global picture whereby violent non-state actors target energy infrastructures to air grievances, communicate to governments, impact state economic interests, or capture revenue in the form of hijacking, kidnapping ransoms, theft. And, for politically motivated groups, such as those engaged in insurgencies, attacking industry assets garners media coverage serving as a facilitator for international attention. This research note will introduce EIAD and position its utility within various research areas where the targeting of energy infrastructure, or more broadly energy infrastructure vulnerability, has been addressed, either directly or indirectly. We also provide a snapshot of the initial analysis of the data between 1980-2011, noting specific temporal and spatial trends, and then conclude with a brief discussion on the contribution of EIAD, highlighting future research trajectories. 

  1. Acid Rain Students Do Original Research.

    Outdoor Communicator, 1984

    1984-01-01

    At Park Senior High School (Cottage Grove, Minnesota), 46 juniors and seniors planted 384 red pine seedlings in connection with their original research on acid rain, with advice from Dr. Harriet Stubbs, director of the Acid Precipitation Awareness Program (West Saint Paul), which has been developing acid rain teaching materials. (MH)

  2. Intra-disciplinary differences in database coverage and the consequences for bibliometric research

    Faber Frandsen, Tove; Nicolaisen, Jeppe

    2008-01-01

    disciplines focusing on interdisciplinary differences; however, little is known about the potential existence of intradisciplinary differences in database coverage. Focusing on intradisciplinary differences, the article documents large database-coverage differences within two disciplines (economics and......Bibliographic databases (including databases based on open access) are routinely used for bibliometric research. The value of a specific database depends to a large extent on the coverage of the discipline(s) under study. A number of studies have determined the coverage of databases in specific...

  3. Reactor core materials research and integrated material database establishment

    Mainly two research areas were covered in this project. One is to establish the integrated database of nuclear materials, and the other is to study the behavior of reactor core materials, which are usually under the most severe condition in the operating plants. During the stage I of the project (for three years since 1999) in- and out of reactor properties of stainless steel, the major structural material for the core structures of PWR (Pressurized Water Reactor), were evaluated and specification of nuclear grade material was established. And the damaged core components from domestic power plants, e.g. orifice of CVCS, support pin of CRGT, etc. were investigated and the causes were revealed. To acquire more resistant materials to the nuclear environments, development of the alternative alloys was also conducted. For the integrated DB establishment, a task force team was set up including director of nuclear materials technology team, and projector leaders and relevant members from each project. The DB is now opened in public through the Internet

  4. Database application research in real-time data access of accelerator control system

    The control system of Shanghai Synchrotron Radiation Facility (SSRF) is a large-scale distributed real-time control system, It involves many types and large amounts of real-time data access during the operating. Database system has wide application prospects in the large-scale accelerator control system. It is the future development direction of the accelerator control system, to replace the differently dedicated data structures with the mature standardized database system. This article discusses the application feasibility of database system in accelerators based on the database interface technology, real-time data access testing, and system optimization research and to establish the foundation of the wide scale application of database system in the SSRF accelerator control system. Based on the database interface technology, real-time data access testing and system optimization research, this article will introduce the application feasibility of database system in accelerators, and lay the foundation of database system application in the SSRF accelerator control system. (authors)

  5. ProtRepeatsDB: a database of amino acid repeats in genomes

    Chauhan Virander S

    2006-07-01

    Full Text Available Abstract Background Genome wide and cross species comparisons of amino acid repeats is an intriguing problem in biology mainly due to the highly polymorphic nature and diverse functions of amino acid repeats. Innate protein repeats constitute vital functional and structural regions in proteins. Repeats are of great consequence in evolution of proteins, as evident from analysis of repeats in different organisms. In the post genomic era, availability of protein sequences encoded in different genomes provides a unique opportunity to perform large scale comparative studies of amino acid repeats. ProtRepeatsDB http://bioinfo.icgeb.res.in/repeats/ is a relational database of perfect and mismatch repeats, access to which is designed as a resource and collection of tools for detection and cross species comparisons of different types of amino acid repeats. Description ProtRepeatsDB (v1.2 consists of perfect as well as mismatch amino acid repeats in the protein sequences of 141 organisms, the genomes of which are now available. The web interface of ProtRepeatsDB consists of different tools to perform repeat s; based on protein IDs, organism name, repeat sequences, and keywords as in FASTA headers, size, frequency, gene ontology (GO annotation IDs and regular expressions (REGEXP describing repeats. These tools also allow formulation of a variety of simple, complex and logical queries to facilitate mining and large-scale cross-species comparisons of amino acid repeats. In addition to this, the database also contains sequence analysis tools to determine repeats in user input sequences. Conclusion ProtRepeatsDB is a multi-organism database of different types of amino acid repeats present in proteins. It integrates useful tools to perform genome wide queries for rapid screening and identification of amino acid repeats and facilitates comparative and evolutionary studies of the repeats. The database is useful for identification of species or organism specific

  6. COPASAAR – A database for proteomic analysis of single amino acid repeats

    Dalby Andrew R

    2005-08-01

    Full Text Available Abstract Background Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and medically significant, and are associated with cancers and neuro-degenerative diseases such as Huntington's Chorea, where a poly-glutamine repeat is responsible for causing the disease. The COPASAAR database is a new tool to facilitate the rapid analysis of single amino acid repeats at a proteome level. The database aims to simplify the comparison of repeat distributions between proteomes in order to provide a better understanding of their function and evolution. Results A comparative analysis of all proteomes in the database (currently 244 shows that single amino acid repeats account for about 12–14% of the proteome of any given species. They are more common in eukaryotes (14% than in either archaea or bacteria (both 13%. Individual analyses of proteomes show that long single amino acid repeats (6+ residues are much more common in the Eukaryotes and that longer repeats are usually made up of hydrophilic amino acids such as glutamine, glutamic acid, asparagine, aspartic acid and serine. Conclusion COPASAAR is a useful tool for comparative proteomics that provides rapid access to amino acid repeat data that can be readily data-mined. The COPASAAR database can be queried at the kingdom, proteome or individual protein level. As the amount of available proteome data increases this will be increasingly important in order to automate proteome comparison. The insights gained from these studies will give a better insight into the evolution of protein sequence and function.

  7. 77 FR 66622 - Submission for OMB Review; Comment Request: National Database for Autism Research (NDAR) Data...

    2012-11-06

    ... Database for Autism Research (NDAR) Data Access Request SUMMARY: Under the provisions of Section 3507(a)(1... control number. Proposed Collection: Title: National Database for Autism Research (NDAR) Data Access... organization or corporations with approved assurance from the DHHS Office of Human Research Protections...

  8. LLNL Middle East and North Africa research database

    The Lawrence Livermore National Laboratory (LLNL) Comprehensive Nuclear-Test-Ban Treaty Research and Development (CTBT R and D) program has made significant progress populating a comprehensive seismic research database (RDB) for seismic events and derived research products in the Middle East and North Africa (MENA). Our original ME/NA study region has enlarged and is now defined as an area including the Middle East, Africa, Europe, Southwest Asia, the Former Soviet Union and the Scandinavian/Arctic region. The LLNL RDB will facilitate calibration of all International Monitoring System (IMS) stations (primary and auxiliary) or their surrogates (if not yet installed) as well as a variety of gamma stations. The RDB provides not only a coherent framework in which to store and organize large volumes of collected seismic waveforms and associated event parameter information, but also provides an efficient data processing/research environment for deriving location and discrimination correction sur faces and capabilities. In order to accommodate large volumes of data from many sources with diverse formats the RDB is designed to be flexible and extensible in addition to maintaining detailed quality control information and associated metadata. Station parameters, instrument responses, phase pick information, and event bulletins were compiled and made available through the RDB. For seismic events in the MENA region occurring between 1976 and 1999, we have systematically assembled, quality checked and organized event waveforms; continuous seismic data from 1990 to present are archived for many stations. Currently, over 11,400 seismic events and 1.2 million waveforms are maintained in the RDB and made readily available to researchers. In addition to open sources of seismic data, we have established collaborative relationships with several ME/NA countries that have yielded additional ground truth and broadband waveform data essential for regional calibration and capability

  9. USDA food and nutrient databases provide the infrastructure for food and nutrition research, policy, and practice.

    Ahuja, Jaspreet K C; Moshfegh, Alanna J; Holden, Joanne M; Harris, Ellen

    2013-02-01

    The USDA food and nutrient databases provide the basic infrastructure for food and nutrition research, nutrition monitoring, policy, and dietary practice. They have had a long history that goes back to 1892 and are unique, as they are the only databases available in the public domain that perform these functions. There are 4 major food and nutrient databases released by the Beltsville Human Nutrition Research Center (BHNRC), part of the USDA's Agricultural Research Service. These include the USDA National Nutrient Database for Standard Reference, the Dietary Supplement Ingredient Database, the Food and Nutrient Database for Dietary Studies, and the USDA Food Patterns Equivalents Database. The users of the databases are diverse and include federal agencies, the food industry, health professionals, restaurants, software application developers, academia and research organizations, international organizations, and foreign governments, among others. Many of these users have partnered with BHNRC to leverage funds and/or scientific expertise to work toward common goals. The use of the databases has increased tremendously in the past few years, especially the breadth of uses. These new uses of the data are bound to increase with the increased availability of technology and public health emphasis on diet-related measures such as sodium and energy reduction. Hence, continued improvement of the databases is important, so that they can better address these challenges and provide reliable and accurate data. PMID:23269654

  10. An integrated database to support research on Escherichia coli

    Baehr, A.; Dunham, G.; Matsuda, Hideo; Michaels, G.; Taylor, R.; Overbeek, R.; Rudd, K.E. [National Inst. of Mental Health, Bethesda, MD (United States); Ginsburg, A.; Joerg, D.; Kazic, T. [Washington Univ., St. Louis, MO (United States). Dept. of Genetics; Hagstrom, R.; Zawada, D. [Argonne National Lab., IL (United States); Smith, C.; Yoshida, Kaoru [Lawrence Berkeley Lab., CA (United States)

    1992-01-01

    We have used logic programming to design and implement a prototype database of genomic information for the model bacterial organism Escherichia coli. This report presents the fundamental database primitives that can be used to access and manipulate data relating to the E. coli genome. The present system, combined with a tutorial manual, provides immediate access to the integrated knowledge base for E. coli chromosome data. It also serves as the foundation for development of more user-friendly interfaces that have the same retrieval power and high-level tools to analyze complex chromosome organization.

  11. Research of database-based modeling for mining management system

    WU Hai-feng; JIN Zhi-xin; BAI Xi-jun

    2005-01-01

    Put forward the method to construct the simulation model automatically with database-based automatic modeling(DBAM) for mining system. Designed the standard simulation model linked with some open cut Pautomobile dispatch system. Analyzed and finded out the law among them, and designed model maker to realize the automatic programming of the new model program.

  12. Research and development of Chinese LCA database and LCA software

    GONG Xianzheng; NIE Zuoren; Wang Zhihong; ZUO Tieyong

    2006-01-01

    This paper detailed introduces the related work for building Chinese National Database, Sinocenter, of materials life cycle assessment (MLCA) and developing the environmental burden dataset of materials.The MLCA database was built in 2004, and the basic framework mainly includes LCA methodology, materials environmental dataset about energy consumption, resource input and environmental emissions.Nowadays, the database contains about fifty-thousand records of the main materials industries, such as cement, iron and steel, nonferrous metal, etc., and also includes the primary LCI data of fossil fuels and electricity grid in China.At the same time, the LCA method localization work is going on, for instance, calculated the resource characterization factors of 42 kinds of metal and 58 sorts of nonmetal, and also obtained some heavy metal impact factors in water.Based on the database, the iron and steel dataset has been developed with the data quality analysis, and some environmental burden data could be queried in our website, www.cnmlca.com, in the future.Lastly, according to the framework of the ISO14040 series standards, the antitype of Chinese LCA evaluation system was developed to support materials and products LCA evaluation in China.

  13. Hydrometeorological Database (HMDB) for Practical Research in Ecology

    Novakovskiy, A; V. Elsakov

    2014-01-01

    The regional HydroMeteorological DataBase (HMDB) was designed for easy access to climate data via the Internet. It contains data on various climatic parameters (temperature, precipitation, pressure, humidity, and wind strength and direction) from 190 meteorological stations in Russia and bordering countries for a period of instrumental observations of over 100 years. Open sources were used to ingest data into HMDB. An analytical block was also developed to perform the most common statistical ...

  14. Database of amino acid-nucleotide contacts in the DNA complexes with homeodomain family proteins

    The analysis of amino acid-nucleotide contacts in interfaces of the protein-DNA complexes, intended to find consistencies in the protein-DNA recognition, is a complex problem that requires analysis of the physicochemical characteristics of these contacts, of the positions of the participating amino acids and nucleotides in the chains of the protein and the DNA, respectively, as well as conservatism of these contacts. Thus, those heterogeneous data should be systematized. For this purpose we have developed a database of amino acid-nucleotide contacts ANTPC (Amino acid Nucleotide Type Position Conservation) following the archetypal example of the proteins in the homeodomain family. We show that it can be used for comparison and classification of interfaces of the protein-DNA complexes

  15. The Beltsville Human Nutrition Research Center's Porcine Immunology and Nutrition Resource Database

    Several diverse genomics-based databases have developed to facilitate research with human and rodent models. Current porcine gene databases, however, lack the nutritional and immunological orientation and robust annotation to design effective molecular tools to study relevant pig models. To address ...

  16. USDA food and nutrient databases provide the infrastructure for food and nutrition research, policy and practice

    The USDA food and nutrient databases provide the basic infrastructure for food and nutrition research, nutrition monitoring, and dietary practice. They have had a long history that goes back to 1892, and are unique, as they are the only databases available in the public domain that perform these fu...

  17. Neutron cross-sections database for amino acids and proteins analysis

    Biological materials may be studied using neutrons as an unconventional tool of analysis. Dynamics and structures data can be obtained for amino acids, protein and others cellular components by neutron cross sections determinations especially for applications in nuclear purity and conformation analysis. The instrument used for this is the crystal spectrometer of the Instituto de Engenharia Nuclear (IEN-CNEN-RJ), the only one in Latin America that uses neutrons for this type of analyzes and it is installed in one of the reactor Argonauta irradiation channels. The experimentally values obtained are compared with calculated values using literature data with a rigorous analysis of the chemical composition, conformation and molecular structure analysis of the materials. A neutron cross-section database was constructed to assist in determining molecular dynamic, structure and formulae of biological materials. The database contains neutron cross-sections values of all amino acids, chemical elements, molecular groups, auxiliary radicals, as well as values of constants and parameters necessary for the analysis. An unprecedented analytical procedure was developed using the neutron cross section parceling and grouping method for data manipulation. This database is a result of measurements obtained from twenty amino acids that were provided by different manufactories and are used in oral administration in hospital individuals for nutritional applications. It was also constructed a small data file of compounds with different molecular groups including carbon, nitrogen, sulfur and oxygen, all linked to hydrogen atoms. A review of global and national scene in the acquisition of neutron cross sections data, the formation of libraries and the application of neutrons for analyzing biological materials is presented. This database has further application in protein analysis and the neutron cross-section from the insulin was estimated. (author)

  18. Neutron cross-sections database for amino acids and proteins analysis

    Voi, Dante L.; Ferreira, Francisco de O.; Nunes, Rogerio Chaffin, E-mail: dante@ien.gov.br, E-mail: fferreira@ien.gov.br, E-mail: Chaffin@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Rocha, Helio F. da, E-mail: hrocha@gbl.com.br [Universidade Federal do Rio de Janeiro (IPPMG/UFRJ), Rio de Janeiro, RJ (Brazil). Instituto de Pediatria

    2015-07-01

    Biological materials may be studied using neutrons as an unconventional tool of analysis. Dynamics and structures data can be obtained for amino acids, protein and others cellular components by neutron cross sections determinations especially for applications in nuclear purity and conformation analysis. The instrument used for this is the crystal spectrometer of the Instituto de Engenharia Nuclear (IEN-CNEN-RJ), the only one in Latin America that uses neutrons for this type of analyzes and it is installed in one of the reactor Argonauta irradiation channels. The experimentally values obtained are compared with calculated values using literature data with a rigorous analysis of the chemical composition, conformation and molecular structure analysis of the materials. A neutron cross-section database was constructed to assist in determining molecular dynamic, structure and formulae of biological materials. The database contains neutron cross-sections values of all amino acids, chemical elements, molecular groups, auxiliary radicals, as well as values of constants and parameters necessary for the analysis. An unprecedented analytical procedure was developed using the neutron cross section parceling and grouping method for data manipulation. This database is a result of measurements obtained from twenty amino acids that were provided by different manufactories and are used in oral administration in hospital individuals for nutritional applications. It was also constructed a small data file of compounds with different molecular groups including carbon, nitrogen, sulfur and oxygen, all linked to hydrogen atoms. A review of global and national scene in the acquisition of neutron cross sections data, the formation of libraries and the application of neutrons for analyzing biological materials is presented. This database has further application in protein analysis and the neutron cross-section from the insulin was estimated. (author)

  19. Landslide databases for applied landslide impact research: the example of the landslide database for the Federal Republic of Germany

    Damm, Bodo; Klose, Martin

    2014-05-01

    This contribution presents an initiative to develop a national landslide database for the Federal Republic of Germany. It highlights structure and contents of the landslide database and outlines its major data sources and the strategy of information retrieval. Furthermore, the contribution exemplifies the database potentials in applied landslide impact research, including statistics of landslide damage, repair, and mitigation. The landslide database offers due to systematic regional data compilation a differentiated data pool of more than 5,000 data sets and over 13,000 single data files. It dates back to 1137 AD and covers landslide sites throughout Germany. In seven main data blocks, the landslide database stores besides information on landslide types, dimensions, and processes, additional data on soil and bedrock properties, geomorphometry, and climatic or other major triggering events. A peculiarity of this landslide database is its storage of data sets on land use effects, damage impacts, hazard mitigation, and landslide costs. Compilation of landslide data is based on a two-tier strategy of data collection. The first step of information retrieval includes systematic web content mining and exploration of online archives of emergency agencies, fire and police departments, and news organizations. Using web and RSS feeds and soon also a focused web crawler, this enables effective nationwide data collection for recent landslides. On the basis of this information, in-depth data mining is performed to deepen and diversify the data pool in key landslide areas. This enables to gather detailed landslide information from, amongst others, agency records, geotechnical reports, climate statistics, maps, and satellite imagery. Landslide data is extracted from these information sources using a mix of methods, including statistical techniques, imagery analysis, and qualitative text interpretation. The landslide database is currently migrated to a spatial database system

  20. Design and deployment of a large brain-image database for clinical and nonclinical research

    Yang, Guo Liang; Lim, Choie Cheio Tchoyoson; Banukumar, Narayanaswami; Aziz, Aamer; Hui, Francis; Nowinski, Wieslaw L.

    2004-04-01

    An efficient database is an essential component of organizing diverse information on image metadata and patient information for research in medical imaging. This paper describes the design, development and deployment of a large database system serving as a brain image repository that can be used across different platforms in various medical researches. It forms the infrastructure that links hospitals and institutions together and shares data among them. The database contains patient-, pathology-, image-, research- and management-specific data. The functionalities of the database system include image uploading, storage, indexing, downloading and sharing as well as database querying and management with security and data anonymization concerns well taken care of. The structure of database is multi-tier client-server architecture with Relational Database Management System, Security Layer, Application Layer and User Interface. Image source adapter has been developed to handle most of the popular image formats. The database has a user interface based on web browsers and is easy to handle. We have used Java programming language for its platform independency and vast function libraries. The brain image database can sort data according to clinically relevant information. This can be effectively used in research from the clinicians" points of view. The database is suitable for validation of algorithms on large population of cases. Medical images for processing could be identified and organized based on information in image metadata. Clinical research in various pathologies can thus be performed with greater efficiency and large image repositories can be managed more effectively. The prototype of the system has been installed in a few hospitals and is working to the satisfaction of the clinicians.

  1. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research.

    Post, Andrew; Kurc, Tahsin; Overcash, Marc; Cantrell, Dedra; Morris, Tim; Eckerson, Kristi; Tsui, Circe; Willey, Terry; Quyyumi, Arshed; Eapen, Danny; Umpierrez, Guillermo; Ziemer, David; Saltz, Joel

    2011-01-01

    In the CTSA era there is great interest in aggregating and comparing populations across institutions. These sites likely represent data differently in their clinical data warehouses and other databases. Clinical data warehouses frequently are structured in a generalized way that supports many constituencies. For research, there is a need to transform these heterogeneous data into a shared representation, and to perform categorization and interpretation to optimize the data representation for investigators. We are addressing this need by extending an existing temporal abstraction-based clinical database query system, PROTEMPA. The extended system allows specifying data types of interest in federated databases, extracting the data into a shared representation, transforming it through categorization and interpretation, and loading it into a registry database that can be refreshed. Such a registry's access control, data representation and query tools can be tailored to the needs of research while keeping local databases as the source of truth. PMID:22211179

  2. A Relational Database of WHO Mortality Data Prepared to Facilitate Global Mortality Research

    Albert de Roos

    2015-09-01

    Full Text Available Detailed world mortality data such as collected by the World Health Organization gives a wealth of information about causes of death worldwide over a time span of 60 year. However, the raw mortality data in text format as provided by the WHO is not directly suitable for systematic research and data mining. In this Data Paper, a relational database is presented that is created from the raw WHO mortality data set and includes mortality rates, an ICD-code table and country reference data. This enriched database, as a corpus of global mortality data, can be readily imported in relational databases but can also function as the data source for other types of databases. The use of this database can therefore greatly facilitate global epidemiological research that may provide new clues to genetic or environmental factors in the origins of diseases.

  3. Nigeria Anopheles vector database: an overview of 100 years' research.

    Patricia Nkem Okorie

    Full Text Available Anopheles mosquitoes are important vectors of malaria and lymphatic filariasis (LF, which are major public health diseases in Nigeria. Malaria is caused by infection with a protozoan parasite of the genus Plasmodium and LF by the parasitic worm Wuchereria bancrofti. Updating our knowledge of the Anopheles species is vital in planning and implementing evidence based vector control programs. To present a comprehensive report on the spatial distribution and composition of these vectors, all published data available were collated into a database. Details recorded for each source were the locality, latitude/longitude, time/period of study, species, abundance, sampling/collection methods, morphological and molecular species identification methods, insecticide resistance status, including evidence of the kdr allele, and P. falciparum sporozoite rate and W. bancrofti microfilaria prevalence. This collation resulted in a total of 110 publications, encompassing 484,747 Anopheles mosquitoes in 632 spatially unique descriptions at 142 georeferenced locations being identified across Nigeria from 1900 to 2010. Overall, the highest number of vector species reported included An. gambiae complex (65.2%, An. funestus complex (17.3%, An. gambiae s.s. (6.5%. An. arabiensis (5.0% and An. funestus s.s. (2.5%, with the molecular forms An. gambiae M and S identified at 120 locations. A variety of sampling/collection and species identification methods were used with an increase in molecular techniques in recent decades. Insecticide resistance to pyrethroids and organochlorines was found in the main Anopheles species across 45 locations. Presence of P. falciparum and W. bancrofti varied between species with the highest sporozoite rates found in An. gambiae s.s, An. funestus s.s. and An. moucheti, and the highest microfilaria prevalence in An. gambiae s.l., An. arabiensis, and An. gambiae s.s. This comprehensive geo-referenced database provides an essential baseline on

  4. Security and Health Research Databases: The Stakeholders and Questions to Be Addressed

    Stewart, Sara

    2006-01-01

    Health research database security issues abound. Issues include subject confidentiality, data ownership, data integrity and data accessibility. There are also various stakeholders in database security. Each of these stakeholders has a different set of concerns and responsibilities when dealing with security issues. There is an obvious need for training in security issues, so that these issues may be addressed and health research will move on without added obstacles based on misunderstanding s...

  5. The Danish Integrated Database for Labor Market Research: Towards Demystification for the English Speaking Audience

    Bram Timmermans

    2010-01-01

    An increasing number of studies, in a wide range of disciplines, make use of so-called linked employer-employee databases. These detailed databases are only available in a limited number of countries. Denmark is one of the countries that makes this data available to researchers that are connected to a Danish research institute. Due to the sensitivity of the data, access is only granted after a thorough screening process and under strict conditions. Nevertheless, there is an international inte...

  6. Research Reactor Benchmarking Database: Facility Specification and Experimental Data

    This web publication contains the facility specifications, experiment descriptions, and corresponding experimental data for nine different research reactors covering a wide range of research reactor types, power levels and experimental configurations. Each data set was prepared in order to serve as a stand-alone resource of well documented experimental data, which can subsequently be used in benchmarking and validation of the neutronic and thermal-hydraulic computational methods and tools employed for improved utilization, operation and safety analysis of research reactors

  7. Knowledge map of artemisinin research in SCI and Medline database

    Qiang Yao , Jing Chen , Peng-Hui Lyu , Shi-Jing Zhang , Fei-Cheng Ma & Jian-Guo Fang

    2012-01-01

    Background & objectives: Artemisinin was first extracted from the herb Artemisia annua which has been used formany centuries in Chinese traditional medicine as a treatment for fever and malaria. It has been given the 2011Lasker-DeBakey clinical medical research award. In this paper, knowledge map of artemisinin research wasdrawn to provide some information for global researchers interested in artemisinin and its relevant references.Methods: In this work, bibliometric analysis and knowledge vi...

  8. Research in Mobile Database Query Optimization and Processing

    Agustinus Borgy Waluyo

    2005-01-01

    Full Text Available The emergence of mobile computing provides the ability to access information at any time and place. However, as mobile computing environments have inherent factors like power, storage, asymmetric communication cost, and bandwidth limitations, efficient query processing and minimum query response time are definitely of great interest. This survey groups a variety of query optimization and processing mechanisms in mobile databases into two main categories, namely: (i query processing strategy, and (ii caching management strategy. Query processing includes both pull and push operations (broadcast mechanisms. We further classify push operation into on-demand broadcast and periodic broadcast. Push operation (on-demand broadcast relates to designing techniques that enable the server to accommodate multiple requests so that the request can be processed efficiently. Push operation (periodic broadcast corresponds to data dissemination strategies. In this scheme, several techniques to improve the query performance by broadcasting data to a population of mobile users are described. A caching management strategy defines a number of methods for maintaining cached data items in clients' local storage. This strategy considers critical caching issues such as caching granularity, caching coherence strategy and caching replacement policy. Finally, this survey concludes with several open issues relating to mobile query optimization and processing strategy.

  9. Research on Data Sharing between AutoCAD and MapGIS in Cadastral Database Construction

    Yang Cai; Jiajia Liu

    2010-01-01

    In the Second Chinese Country Survey, MAPGIS (Map Geographic Information System) is widely used all over the country in the Cadastral Database Construction. There are plenty original data is saved in the AutoCAD (Auto Computer Aided Design) data format. Therefore it is important to find a way which can exchange and share the data between AutoCAD and MAPGIS effectively and efficiently. In order to use MapGIS cadastral management system building cadastral database, it researched the current tra...

  10. The Pitfalls of Cyberspace and Electronic Database Research--Who Sells What to Whom for Which Audience?

    Willey, Susan

    2000-01-01

    Raises questions about the validity and reliability of doing research online via the proliferation of academic databases. Finds different versions of the Lexis-Nexis database have differing search capabilities. Argues that dependence on database research findings means dependence on decisions made by a few people who design search engines and…

  11. Large-scale spatial population databases in infectious disease research.

    Linard, Catherine; Tatem, Andrew J

    2012-01-01

    Modelling studies on the spatial distribution and spread of infectious diseases are becoming increasingly detailed and sophisticated, with global risk mapping and epidemic modelling studies now popular. Yet, in deriving populations at risk of disease estimates, these spatial models must rely on existing global and regional datasets on population distribution, which are often based on outdated and coarse resolution data. Moreover, a variety of different methods have been used to model population distribution at large spatial scales. In this review we describe the main global gridded population datasets that are freely available for health researchers and compare their construction methods, and highlight the uncertainties inherent in these population datasets. We review their application in past studies on disease risk and dynamics, and discuss how the choice of dataset can affect results. Moreover, we highlight how the lack of contemporary, detailed and reliable data on human population distribution in low income countries is proving a barrier to obtaining accurate large-scale estimates of population at risk and constructing reliable models of disease spread, and suggest research directions required to further reduce these barriers. PMID:22433126

  12. Large-scale spatial population databases in infectious disease research

    Linard Catherine

    2012-03-01

    Full Text Available Abstract Modelling studies on the spatial distribution and spread of infectious diseases are becoming increasingly detailed and sophisticated, with global risk mapping and epidemic modelling studies now popular. Yet, in deriving populations at risk of disease estimates, these spatial models must rely on existing global and regional datasets on population distribution, which are often based on outdated and coarse resolution data. Moreover, a variety of different methods have been used to model population distribution at large spatial scales. In this review we describe the main global gridded population datasets that are freely available for health researchers and compare their construction methods, and highlight the uncertainties inherent in these population datasets. We review their application in past studies on disease risk and dynamics, and discuss how the choice of dataset can affect results. Moreover, we highlight how the lack of contemporary, detailed and reliable data on human population distribution in low income countries is proving a barrier to obtaining accurate large-scale estimates of population at risk and constructing reliable models of disease spread, and suggest research directions required to further reduce these barriers.

  13. Raman database of amino acids solutions: A critical study of Extended Multiplicative Signal Correction

    Candeloro, Patrizio

    2013-01-01

    The Raman spectra of biological materials always exhibit complex profiles, constituting several peaks and/or bands which arise due to the large variety of biomolecules. The extraction of quantitative information from these spectra is not a trivial task. While qualitative information can be retrieved from the changes in peaks frequencies or from the appearance/disappearance of some peaks, quantitative analysis requires an examination of peak intensities. Unfortunately in biological samples it is not easy to identify a reference peak for normalizing intensities, and this makes it very difficult to study the peak intensities. In the last decades a more refined mathematical tool, the extended multiplicative signal correction (EMSC), has been proposed for treating infrared spectra, which is also capable of providing quantitative information. From the mathematical and physical point of view, EMSC can also be applied to Raman spectra, as recently proposed. In this work the reliability of the EMSC procedure is tested by application to a well defined biological system: the 20 standard amino acids and their combination in peptides. The first step is the collection of a Raman database of these 20 amino acids, and subsequently EMSC processing is applied to retrieve quantitative information from amino acids mixtures and peptides. A critical review of the results is presented, showing that EMSC has to be carefully handled for complex biological systems. © 2013 The Royal Society of Chemistry.

  14. A meta-database comparison from various European Research and Monitoring Networks dedicated to forest sites

    Danielewska A

    2013-01-01

    Full Text Available Of a wide variety of international forest research and monitoring networks, several networks are dedicated to the effects of climate change on forests, while the effects of anthropogenic pollutants on forests have been a major area for both monitoring and research for decades. The large amounts of data already obtained within existing monitoring programmes and large-scale international projects can be used to increase understanding of the state and potential of forest mitigation and adaptation to climate change in a polluted environment, and a major challenge now is to evaluate and integrate the presently available databases. We present a meta-database with the main goal to highlight available data and integrate the information about research and monitoring of selected European Research and Monitoring Networks (ERMNs. Depending on the selected ERMNs, the list of variables and the measurement units differ widely in the databases. As a result, activities related to the identification, evaluation and integration of the presently available databases are important for the scientific community. Furthermore, and equally important, the recognition of current knowledge gaps and future needed research is made easier. This analysis suggests that: ground-level ozone is under-investigated, although it is one of the pollutants of greatest concern to forests; in addition to CO2, long-term other greenhouse gasses (GHG flux measurements should be carried out; there is still a need of improving links between monitoring of atmospheric changes and impacts on forests; research-oriented manipulative experiments in the forests are missing.

  15. Assessing urology and nephrology research activity in Arab countries using ISI web of science bibliometric database

    Waleed M. Sweileh; Zyoud, Sa’ed H.; Al-Jabi, Samah W.; Sawalha, Ansam F

    2014-01-01

    Background Bibliometric analysis is increasingly being used for research assessment. The main objective of this study was to assess research output in Urology and Nephrology subject from the Arab countries. Original scientific articles or reviews published from the 21 Arab countries in “Urology and Nephrology” subject were screened using the ISI Web of Science database. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies by analyzing the...

  16. Finding our foundation: Analysis of the LISA database for research retrievability

    Perryman, Carol; Lu, Dihui

    2006-01-01

    Objective: The primary objective of this study is to examine the Library and Information Science Abstracts (LISA) database to determine if research literature can consistently be retrieved by using keywords identifying the research methodologies used. Question: For the journals named, are articles identified as ‘research’ able to be consistently retrieved by using keywords related to research methodology? Methods: Citations from the top 10 Library and Information Science journals for ...

  17. Moving to Google Cloud: Renovation of Global Borehole Temperature Database for Climate Research

    Xiong, Y.; Huang, S.

    2013-12-01

    Borehole temperature comprises an independent archive of information on climate change which is complementary to the instrumental and other proxy climate records. With support from the international geothermal community, a global database of borehole temperatures has been constructed for the specific purpose of the study on climate change. Although this database has become an important data source in climate research, there are certain limitations partially because the framework of the existing borehole temperature database was hand-coded some twenty years ago. A database renovation work is now underway to take the advantages of the contemporary online database technologies. The major intended improvements include 1) dynamically linking a borehole site to Google Earth to allow for inspection of site specific geographical information; 2) dynamically linking an original key reference of a given borehole site to Google Scholar to allow for a complete list of related publications; and 3) enabling site selection and data download based on country, coordinate range, and contributor. There appears to be a good match between the enhancement requirements for this database and the functionalities of the newly released Google Fusion Tables application. Google Fusion Tables is a cloud-based service for data management, integration, and visualization. This experimental application can consolidate related online resources such as Google Earth, Google Scholar, and Google Drive for sharing and enriching an online database. It is user friendly, allowing users to apply filters and to further explore the internet for additional information regarding the selected data. The users also have ways to map, to chart, and to calculate on the selected data, and to download just the subset needed. The figure below is a snapshot of the database currently under Google Fusion Tables renovation. We invite contribution and feedback from the geothermal and climate research community to make the

  18. Development of a pseudo/anonymised primary care research database: Proof-of-concept study.

    MacRury, Sandra; Finlayson, Jim; Hussey-Wilson, Susan; Holden, Samantha

    2016-06-01

    General practice records present a comprehensive source of data that could form a variety of anonymised or pseudonymised research databases to aid identification of potential research participants regardless of location. A proof-of-concept study was undertaken to extract data from general practice systems in 15 practices across the region to form pseudo and anonymised research data sets. Two feasibility studies and a disease surveillance study compared numbers of potential study participants and accuracy of disease prevalence, respectively. There was a marked reduction in screening time and increase in numbers of potential study participants identified with the research repository compared with conventional methods. Accurate disease prevalence was established and enhanced with the addition of selective text mining. This study confirms the potential for development of national anonymised research database from general practice records in addition to improving data collection for local or national audits and epidemiological projects. PMID:24935212

  19. Development of a computational database for probabilistic safety assessment of nuclear research reactors

    Macedo, Vagner S.; Oliveira, Patricia S. Pagetti de; Andrade, Delvonei Alves de, E-mail: vagner.macedo@usp.br, E-mail: patricia@ipen.br, E-mail: delvonei@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The objective of this work is to describe the database being developed at IPEN - CNEN / SP for application in the Probabilistic Safety Assessment of nuclear research reactors. The database can be accessed by means of a computational program installed in the corporate computer network, named IPEN Intranet, and this access will be allowed only to professionals previously registered. Data updating, editing and searching tasks will be controlled by a system administrator according to IPEN Intranet security rules. The logical model and the physical structure of the database can be represented by an Entity Relationship Model, which is based on the operational routines performed by IPEN - CNEN / SP users. The web application designed for the management of the database is named PSADB. It is being developed with MySQL database software and PHP programming language is being used. Data stored in this database are divided into modules that refer to technical specifications, operating history, maintenance history and failure events associated with the main components of the nuclear facilities. (author)

  20. Development of a computational database for probabilistic safety assessment of nuclear research reactors

    The objective of this work is to describe the database being developed at IPEN - CNEN / SP for application in the Probabilistic Safety Assessment of nuclear research reactors. The database can be accessed by means of a computational program installed in the corporate computer network, named IPEN Intranet, and this access will be allowed only to professionals previously registered. Data updating, editing and searching tasks will be controlled by a system administrator according to IPEN Intranet security rules. The logical model and the physical structure of the database can be represented by an Entity Relationship Model, which is based on the operational routines performed by IPEN - CNEN / SP users. The web application designed for the management of the database is named PSADB. It is being developed with MySQL database software and PHP programming language is being used. Data stored in this database are divided into modules that refer to technical specifications, operating history, maintenance history and failure events associated with the main components of the nuclear facilities. (author)

  1. The Chinchilla Research Resource Database: resource for an otolaryngology disease model

    Shimoyama, Mary; Smith, Jennifer R.; De Pons, Jeff; Tutaj, Marek; Khampang, Pawjai; Hong, Wenzhou; Erbe, Christy B.; Ehrlich, Garth D.; Bakaletz, Lauren O.; Kerschner, Joseph E.

    2016-01-01

    The long-tailed chinchilla (Chinchilla lanigera) is an established animal model for diseases of the inner and middle ear, among others. In particular, chinchilla is commonly used to study diseases involving viral and bacterial pathogens and polymicrobial infections of the upper respiratory tract and the ear, such as otitis media. The value of the chinchilla as a model for human diseases prompted the sequencing of its genome in 2012 and the more recent development of the Chinchilla Research Resource Database (http://crrd.mcw.edu) to provide investigators with easy access to relevant datasets and software tools to enhance their research. The Chinchilla Research Resource Database contains a complete catalog of genes for chinchilla and, for comparative purposes, human. Chinchilla genes can be viewed in the context of their genomic scaffold positions using the JBrowse genome browser. In contrast to the corresponding records at NCBI, individual gene reports at CRRD include functional annotations for Disease, Gene Ontology (GO) Biological Process, GO Molecular Function, GO Cellular Component and Pathway assigned to chinchilla genes based on annotations from the corresponding human orthologs. Data can be retrieved via keyword and gene-specific searches. Lists of genes with similar functional attributes can be assembled by leveraging the hierarchical structure of the Disease, GO and Pathway vocabularies through the Ontology Search and Browser tool. Such lists can then be further analyzed for commonalities using the Gene Annotator (GA) Tool. All data in the Chinchilla Research Resource Database is freely accessible and downloadable via the CRRD FTP site or using the download functions available in the search and analysis tools. The Chinchilla Research Resource Database is a rich resource for researchers using, or considering the use of, chinchilla as a model for human disease. Database URL: http://crrd.mcw.edu PMID:27173523

  2. The Chinchilla Research Resource Database: resource for an otolaryngology disease model.

    Shimoyama, Mary; Smith, Jennifer R; De Pons, Jeff; Tutaj, Marek; Khampang, Pawjai; Hong, Wenzhou; Erbe, Christy B; Ehrlich, Garth D; Bakaletz, Lauren O; Kerschner, Joseph E

    2016-01-01

    The long-tailed chinchilla (Chinchilla lanigera) is an established animal model for diseases of the inner and middle ear, among others. In particular, chinchilla is commonly used to study diseases involving viral and bacterial pathogens and polymicrobial infections of the upper respiratory tract and the ear, such as otitis media. The value of the chinchilla as a model for human diseases prompted the sequencing of its genome in 2012 and the more recent development of the Chinchilla Research Resource Database (http://crrd.mcw.edu) to provide investigators with easy access to relevant datasets and software tools to enhance their research. The Chinchilla Research Resource Database contains a complete catalog of genes for chinchilla and, for comparative purposes, human. Chinchilla genes can be viewed in the context of their genomic scaffold positions using the JBrowse genome browser. In contrast to the corresponding records at NCBI, individual gene reports at CRRD include functional annotations for Disease, Gene Ontology (GO) Biological Process, GO Molecular Function, GO Cellular Component and Pathway assigned to chinchilla genes based on annotations from the corresponding human orthologs. Data can be retrieved via keyword and gene-specific searches. Lists of genes with similar functional attributes can be assembled by leveraging the hierarchical structure of the Disease, GO and Pathway vocabularies through the Ontology Search and Browser tool. Such lists can then be further analyzed for commonalities using the Gene Annotator (GA) Tool. All data in the Chinchilla Research Resource Database is freely accessible and downloadable via the CRRD FTP site or using the download functions available in the search and analysis tools. The Chinchilla Research Resource Database is a rich resource for researchers using, or considering the use of, chinchilla as a model for human disease.Database URL: http://crrd.mcw.edu. PMID:27173523

  3. An Integrated Sequence-Structure Database incorporating matching mRNA sequence, amino acid sequence and protein three-dimensional structure data.

    Adzhubei, I A; Adzhubei, A. A.; Neidle, S.

    1998-01-01

    We have constructed a non-homologous database, termed the Integrated Sequence-Structure Database (ISSD) which comprises the coding sequences of genes, amino acid sequences of the corresponding proteins, their secondary structure and straight phi,psi angles assignments, and polypeptide backbone coordinates. Each protein entry in the database holds the alignment of nucleotide sequence, amino acid sequence and the PDB three-dimensional structure data. The nucleotide and amino acid sequences for ...

  4. Quality standards for real-world research. Focus on observational database studies of comparative effectiveness.

    Roche, Nicolas; Reddel, Helen; Martin, Richard; Brusselle, Guy; Papi, Alberto; Thomas, Mike; Postma, Dirjke; Thomas, Vicky; Rand, Cynthia; Chisholm, Alison; Price, David

    2014-02-01

    Real-world research can use observational or clinical trial designs, in both cases putting emphasis on high external validity, to complement the classical efficacy randomized controlled trials (RCTs) with high internal validity. Real-world research is made necessary by the variety of factors that can play an important a role in modulating effectiveness in real life but are often tightly controlled in RCTs, such as comorbidities and concomitant treatments, adherence, inhalation technique, access to care, strength of doctor-caregiver communication, and socio-economic and other organizational factors. Real-world studies belong to two main categories: pragmatic trials and observational studies, which can be prospective or retrospective. Focusing on comparative database observational studies, the process aimed at ensuring high-quality research can be divided into three parts: preparation of research, analyses and reporting, and discussion of results. Key points include a priori planning of data collection and analyses, identification of appropriate database(s), proper outcomes definition, study registration with commitment to publish, bias minimization through matching and adjustment processes accounting for potential confounders, and sensitivity analyses testing the robustness of results. When these conditions are met, observational database studies can reach a sufficient level of evidence to help create guidelines (i.e., clinical and regulatory decision-making). PMID:24559028

  5. A meta-database comparison from various European Research and Monitoring Networks dedicated to forest sites

    Danielewska, A.; Clarke, N.; Olejnik, Janusz; Hansen, K.; de Vries, W.; Lundin, L.; Tuovinen, J-P.; Fischer, R.; Urbaniak, M.; Paoletti, E.

    2013-01-01

    Roč. 6, JAN 2013 (2013), s. 1-9. ISSN 1971-7458 Institutional support: RVO:67179843 Keywords : Research and Monitoring Network * Meta-database * Forest * Monitoring Subject RIV: EH - Ecology, Behaviour Impact factor: 1.150, year: 2013

  6. Current trends and new challenges of databases and web applications for systems driven biological research

    Do HanKim

    2010-12-01

    Full Text Available Dynamic and rapidly evolving nature of systems driven research imposes special requirements on the technology, approach, design and architecture of computational infrastructure including database and web application. Several solutions have been proposed to meet the expectations and novel methods have been developed to address the persisting problems of data integration. It is important for researchers to understand different technologies and approaches. Having familiarized with the pros and cons of the existing technologies, researchers can exploit its capabilities to the maximum potential for integrating data. In this review we discuss the architecture, design and key technologies underlying some of the prominent databases (DBs and web applications. We will mention their roles in integration of biological data and investigate some of the emerging design concepts and computational technologies that are likely to have a key role in the future of systems driven biomedical research.

  7. Privacy protection and public goods: building a genetic database for health research in Newfoundland and Labrador

    Kosseim, Patricia; Pullman, Daryl; Perrot-Daley, Astrid; Hodgkinson, Kathy; Street, Catherine; Rahman, Proton

    2013-01-01

    Objective To provide a legal and ethical analysis of some of the implementation challenges faced by the Population Therapeutics Research Group (PTRG) at Memorial University (Canada), in using genealogical information offered by individuals for its genetics research database. Materials and methods This paper describes the unique historical and genetic characteristics of the Newfoundland and Labrador founder population, which gave rise to the opportunity for PTRG to build the Newfoundland Genea...

  8. The Risk of Fracture in Patients With Multiple Sclerosis: The UK General Practice Research Database

    Bazelier, M. T.; van Staa, T.; Uitdehaag, B. M. J.;

    2011-01-01

    conducted a population-based cohort study using data from the UK General Practice Research Database linked to the National Hospital Registry (1997-2008). Incident MS patients (n = 5565) were matched 1:6 by year of birth, sex, and practice with patients without MS (controls). Cox proportional-hazards models...... may be indicated in patients with MS, especially those prescribed GCs or antidepressants. (C) 2011 American Society for Bone and Mineral Research....

  9. Building adisease-specific research database -longitudinal follow-up of thyroid cancer patients

    Vejvalka, J.; Pejcha, T.; Varga, F.; Křenek, M.; Vlček, P.; Jirsa, Ladislav

    Bari : Politecnico di Bari, 2007 - (Sicurello, F.; Mastronardi, G.), s. 111-111 ISBN 978-88-95614-02-1. [Italian Association of Telemedicine and Medical Informatics --- 8th Congress. Bari (IT), 13.12.2007-15.12.2007] R&D Projects: GA AV ČR(CZ) 1ET100750404 Institutional research plan: CEZ:AV0Z10750506 Keywords : research database * thyroid cancer * longitudinal follow-up Subject RIV: IN - Informatics, Computer Science

  10. PeDaB - the personal dosimetry database at the research centre Juelich

    In May, 1997 the mainframe based registration, processing and archiving of personal monitoring data at the research centre Juelich (FZJ) was transferred to a client server system. A complex database application was developed. The client user interface is a Windows based Microsoft ACCESS application which is connected to an ORACLE database via ODBC and TCP/IP. The conversion covered all areas of personal dosimetry including internal and external exposition as well as administrative areas. A higher degree of flexibility, data security and integrity was achieved. (orig.)

  11. GDR (Genome Database for Rosaceae: integrated web resources for Rosaceae genomics and genetics research

    Ficklin Stephen

    2004-09-01

    Full Text Available Abstract Background Peach is being developed as a model organism for Rosaceae, an economically important family that includes fruits and ornamental plants such as apple, pear, strawberry, cherry, almond and rose. The genomics and genetics data of peach can play a significant role in the gene discovery and the genetic understanding of related species. The effective utilization of these peach resources, however, requires the development of an integrated and centralized database with associated analysis tools. Description The Genome Database for Rosaceae (GDR is a curated and integrated web-based relational database. GDR contains comprehensive data of the genetically anchored peach physical map, an annotated peach EST database, Rosaceae maps and markers and all publicly available Rosaceae sequences. Annotations of ESTs include contig assembly, putative function, simple sequence repeats, and anchored position to the peach physical map where applicable. Our integrated map viewer provides graphical interface to the genetic, transcriptome and physical mapping information. ESTs, BACs and markers can be queried by various categories and the search result sites are linked to the integrated map viewer or to the WebFPC physical map sites. In addition to browsing and querying the database, users can compare their sequences with the annotated GDR sequences via a dedicated sequence similarity server running either the BLAST or FASTA algorithm. To demonstrate the utility of the integrated and fully annotated database and analysis tools, we describe a case study where we anchored Rosaceae sequences to the peach physical and genetic map by sequence similarity. Conclusions The GDR has been initiated to meet the major deficiency in Rosaceae genomics and genetics research, namely a centralized web database and bioinformatics tools for data storage, analysis and exchange. GDR can be accessed at http://www.genome.clemson.edu/gdr/.

  12. DOG-SPOT database for comprehensive management of dog genetic research data

    Sutter Nathan B

    2010-12-01

    Full Text Available Abstract Research laboratories studying the genetics of companion animals have no database tools specifically designed to aid in the management of the many kinds of data that are generated, stored and analyzed. We have developed a relational database, "DOG-SPOT," to provide such a tool. Implemented in MS-Access, the database is easy to extend or customize to suit a lab's particular needs. With DOG-SPOT a lab can manage data relating to dogs, breeds, samples, biomaterials, phenotypes, owners, communications, amplicons, sequences, markers, genotypes and personnel. Such an integrated data structure helps ensure high quality data entry and makes it easy to track physical stocks of biomaterials and oligonucleotides.

  13. Respiratory infections research in afghanistan: bibliometric analysis with the database pubmed

    Infectious diseases research in a low-income country like Afghanistan is important. Methods: In this study an internet-based database Pubmed was used for bibliometric analysis of infectious diseases research activity. Research publications entries in PubMed were analysed according to number of publications, topic, publication type, and country of investigators. Results: Between 2002-2011, 226 (77.7%) publications with the following research topics were identified: respiratory infections 3 (1.3%); parasites 8 (3.5%); diarrhoea 10 (4.4%); tuberculosis 10 (4.4%); human immunodeficiency virus (HIV) 11(4.9%); multi-drug resistant bacteria (MDR) 18(8.0%); polio 31(13.7%); leishmania 31(13.7%); malaria 46(20.4%). From 2002-2011, 11 (4.9%) publications were basic science laboratory-based research studies. Between 2002-2011, 8 (3.5%) publications from Afghan institutions were identified. Conclusion: In conclusion, the internet-based database Pubmed can be consulted to collect data for guidance of infectious diseases research activity of low-income countries. The presented data suggest that infectious diseases research in Afghanistan is limited for respiratory infections research, has few studies conducted by Afghan institutions, and limited laboratory-based research contributions. (author)

  14. Second Research Coordination Meeting on Reference Database for Neutron Activation Analysis. Summary Report

    The second meeting of the Co-ordinated Research Project on 'Reference Database for Neutron Activation Analysis'; was held at the IAEA, Vienna from 7-9 May, 2007. A summary of the presentations made by participants is given, along with reports on specifically assigned tasks and subsequent discussions. In order to meet the overall objectives of this CRP, the outputs have been reiterated and new task assignments made. The aims of the Co-ordinated Research Project (CRP) on 'Reference Database for Neutron Activation Analysis' are to improve the status of the database of nuclear constants for k0-NAA, to contribute to the quantification of nuclear structure and decay data, and to remove or reduce some of the discrepancies that exist between the integral constants and values derived from differential data. This CRP originated following the support of the International Nuclear Data Committee (INDC) which advises the Nuclear Data Section (NDS) on nuclear data issues. The INDC recommended in the Summary Report of their meeting of May 2002, INDC/P(02)-23, that a CRP on 'Reference Database for Neutron Activation Analysis' be initiated in 2005

  15. Research progress and prospects of low phytic acid crops

    The contents and deposit forms of phytic acid and its physiological functions were summarized. The researches on the molecular genetic basis and possible mechanisms of low phytic acid mutations were reviewed, and the future perspectives were discussed. (authors)

  16. Status of research reactor spent fuel world-wide: Database summary

    Results complied in the research reactor spent fuel database are used to assess the status of research reactor spent fuel world-wide. Fuel assemblies, their types, enrichment, origin of enrichment and geological distribution among the industrialized and developed countries of the world are discussed. Fuel management practices in wet and dry storage facilities and the concerns of reactor operators about long-term storage of their spent fuel are presented and some of the activities carried out by the International Atomic Energy Agency to address the issues associated with research reactor spent fuel are outlined. (author). 4 refs, 17 figs, 4 tabs

  17. A middle layer solution to support ACID properties for NoSQL databases

    Ayman E. Lotfy

    2016-01-01

    Full Text Available The main objective of this paper is to keep the strengths of RDBMSs as consistency and ACID properties and at the same time providing the benefits that inspired the NoSQL movement through a middle layer. The proposed middle layer uses a four phase commit protocol to ensure: the use of recent data, the use of the Pessimistic technique to forbid others dealing with data while it is used and the data updates residing in many locations to avoid the loss of data and disappointment. This mechanism is required, especially in distributed database application NoSQL based environment, because allowing conflicting transactions to continue not only wastes constrained computing power and decreases bandwidth, but also exacerbates conflicts. The middle layer keeps tracking all running transactions and manages with other layers the execution of concurrent transactions. This solution will help increase both of the scalability, and throughput. Finally, the experimental results show that the throughput of the system improves on increasing the number of middle layers in scenarios and the amount of updates to read in a transaction increases. Also the data are consistent with executing many transactions related to each other through updating the same data. The scalability and availability of the system is not affected while ensuring strict consistency.

  18. Insight: An ontology-based integrated database and analysis platform for epilepsy self-management research.

    Sahoo, Satya S; Ramesh, Priya; Welter, Elisabeth; Bukach, Ashley; Valdez, Joshua; Tatsuoka, Curtis; Bamps, Yvan; Stoll, Shelley; Jobst, Barbara C; Sajatovic, Martha

    2016-10-01

    We present Insight as an integrated database and analysis platform for epilepsy self-management research as part of the national Managing Epilepsy Well Network. Insight is the only available informatics platform for accessing and analyzing integrated data from multiple epilepsy self-management research studies with several new data management features and user-friendly functionalities. The features of Insight include, (1) use of Common Data Elements defined by members of the research community and an epilepsy domain ontology for data integration and querying, (2) visualization tools to support real time exploration of data distribution across research studies, and (3) an interactive visual query interface for provenance-enabled research cohort identification. The Insight platform contains data from five completed epilepsy self-management research studies covering various categories of data, including depression, quality of life, seizure frequency, and socioeconomic information. The data represents over 400 participants with 7552 data points. The Insight data exploration and cohort identification query interface has been developed using Ruby on Rails Web technology and open source Web Ontology Language Application Programming Interface to support ontology-based reasoning. We have developed an efficient ontology management module that automatically updates the ontology mappings each time a new version of the Epilepsy and Seizure Ontology is released. The Insight platform features a Role-based Access Control module to authenticate and effectively manage user access to different research studies. User access to Insight is managed by the Managing Epilepsy Well Network database steering committee consisting of representatives of all current collaborating centers of the Managing Epilepsy Well Network. New research studies are being continuously added to the Insight database and the size as well as the unique coverage of the dataset allows investigators to conduct

  19. Dental health services research utilizing comprehensive clinical databases and information technology.

    Hayden, W J

    1997-01-01

    Marketplace pressures for accountability in dentistry have made clear dental delivery systems' weaknesses in information generation, management, and analysis methods. Without this type of information, dentistry is unable to quantify and document the outcomes of the dental care services it provides. The Pew Health Professions Commission and the Institute of Medicine both suggest that dental schools should be among the leaders in the development and teaching of dental information capabilities, as well as the source of fundamental dental health services research. This paper argues that dental schools are the logical location for the development of valid, reliable, and acceptable health services research methods and databases. It describes the development of an insurance claims database to demonstrate the types of investigations possible, as well as the weaknesses and shortcomings of pure administrative data. PMID:9024342

  20. Development of the Database for Environmental Sound Research and Application (DESRA: Design, Functionality, and Retrieval Considerations

    Brian Gygi

    2010-01-01

    Full Text Available Theoretical and applied environmental sounds research is gaining prominence but progress has been hampered by the lack of a comprehensive, high quality, accessible database of environmental sounds. An ongoing project to develop such a resource is described, which is based upon experimental evidence as to the way we listen to sounds in the world. The database will include a large number of sounds produced by different sound sources, with a thorough background for each sound file, including experimentally obtained perceptual data. In this way DESRA can contain a wide variety of acoustic, contextual, semantic, and behavioral information related to an individual sound. It will be accessible on the Internet and will be useful to researchers, engineers, sound designers, and musicians.

  1. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research

    Post, Andrew; Kurc, Tahsin; Overcash, Marc; Cantrell, Dedra; Morris, Tim; Eckerson, Kristi; Tsui, Circe; Willey, Terry; Quyyumi, Arshed; Eapen, Danny; Umpierrez, Guillermo; Ziemer, David; Saltz, Joel

    2011-01-01

    In the CTSA era there is great interest in aggregating and comparing populations across institutions. These sites likely represent data differently in their clinical data warehouses and other databases. Clinical data warehouses frequently are structured in a generalized way that supports many constituencies. For research, there is a need to transform these heterogeneous data into a shared representation, and to perform categorization and interpretation to optimize the data representation for ...

  2. Third research coordination meeting on reference database for neutron activation analysis. Summary report

    The third meeting of the Co-ordinated Research Project on 'Reference Database for Neutron Activation Analysis' was held at the IAEA, Vienna from 17-19 November 2008. A summary of presentations made by participants is given, reports on specific tasks and subsequent discussions. With the aim of finalising the work of this CRP and in order to meet initial objectives, outputs were discussed and detailed task assignments agreed upon. (author)

  3. Development of a Local Entomological Database for Education and Research using Simulation (Virtual) Methods

    Khater, Emad I.; Mona G. Mahmoud; Enas H. Ghallab; Magdi G. Shehata; Yasser M. Abd El-Latif

    2014-01-01

    Bioinformatics has been regarded as one of the rapidly-evolving fields with enormous impact on the history of life and biomedical sciences. It is an interdisciplinary science that integrates life sciences, mathematics and computer science in order to extract meaningful biological insights from large data sets of raw DNA and protein sequences. Our objective was the development of an entomogenomics database (provisionally named EntomDB) for education and research in entomology (entomology is th...

  4. The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2016 Update on Research.

    Jacobs, Marshall L; Jacobs, Jeffrey P; Pasquali, Sara K; Hill, Kevin D; Hornik, Christoph; O'Brien, Sean M; Shahian, David M; Habib, Robert H; Edwards, Fred H

    2016-09-01

    The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD) is the largest congenital and pediatric cardiac surgical clinical data registry in the world. With more than 400,000 total operations from nearly all centers performing pediatric and congenital heart operations in North America, the STS CHSD is an unparalleled platform for clinical investigation, outcomes research, and quality improvement activities in this subspecialty. In 2015, several major original publications reported analyses of data in the CHSD pertaining to specific diagnostic and procedural groups, age-defined cohorts, or the entire population of patients in the database. Additional publications reported the most recent development, evaluation, and application of metrics for quality measurement and reporting of pediatric and congenital heart operation outcomes. This use of the STS CHSD for outcomes research and for quality measurement continues to expand as database participation and the available wealth of data in it continue to grow. This article reviews outcomes research and quality improvement articles published in 2015 based on STS CHSD data. PMID:27492669

  5. The Subviral RNA Database: a toolbox for viroids, the hepatitis delta virus and satellite RNAs research

    Pelchat Martin

    2006-03-01

    Full Text Available Abstract Background Viroids, satellite RNAs, satellites viruses and the human hepatitis delta virus form the 'brotherhood' of the smallest known infectious RNA agents, known as the subviral RNAs. For most of these species, it is generally accepted that characteristics such as cell movement, replication, host specificity and pathogenicity are encoded in their RNA sequences and their resulting RNA structures. Although many sequences are indexed in publicly available databases, these sequence annotation databases do not provide the advanced searches and data manipulation capability for identifying and characterizing subviral RNA motifs. Description The Subviral RNA database is a web-based environment that facilitates the research and analysis of viroids, satellite RNAs, satellites viruses, the human hepatitis delta virus, and related RNA sequences. It integrates a large number of Subviral RNA sequences, their respective RNA motifs, analysis tools, related publication links and additional pertinent information (ex. links, conferences, announcements, allowing users to efficiently retrieve and analyze relevant information about these small RNA agents. Conclusion With its design, the Subviral RNA Database could be considered as a fundamental building block for the study of these related RNAs. It is freely available via a web browser at the URL: http://subviral.med.uottawa.ca.

  6. MIMIC II: a massive temporal ICU patient database to support research in intelligent patient monitoring

    Saeed, M.; Lieu, C.; Raber, G.; Mark, R. G.

    2002-01-01

    Development and evaluation of Intensive Care Unit (ICU) decision-support systems would be greatly facilitated by the availability of a large-scale ICU patient database. Following our previous efforts with the MIMIC (Multi-parameter Intelligent Monitoring for Intensive Care) Database, we have leveraged advances in networking and storage technologies to develop a far more massive temporal database, MIMIC II. MIMIC II is an ongoing effort: data is continuously and prospectively archived from all ICU patients in our hospital. MIMIC II now consists of over 800 ICU patient records including over 120 gigabytes of data and is growing. A customized archiving system was used to store continuously up to four waveforms and 30 different parameters from ICU patient monitors. An integrated user-friendly relational database was developed for browsing of patients' clinical information (lab results, fluid balance, medications, nurses' progress notes). Based upon its unprecedented size and scope, MIMIC II will prove to be an important resource for intelligent patient monitoring research, and will support efforts in medical data mining and knowledge-discovery.

  7. A DICOM based radiotherapy plan database for research collaboration and reporting

    Westberg, J.; Krogh, S.; Brink, C.; Vogelius, I. R.

    2014-03-01

    Purpose: To create a central radiotherapy (RT) plan database for dose analysis and reporting, capable of calculating and presenting statistics on user defined patient groups. The goal is to facilitate multi-center research studies with easy and secure access to RT plans and statistics on protocol compliance. Methods: RT institutions are able to send data to the central database using DICOM communications on a secure computer network. The central system is composed of a number of DICOM servers, an SQL database and in-house developed software services to process the incoming data. A web site within the secure network allows the user to manage their submitted data. Results: The RT plan database has been developed in Microsoft .NET and users are able to send DICOM data between RT centers in Denmark. Dose-volume histogram (DVH) calculations performed by the system are comparable to those of conventional RT software. A permission system was implemented to ensure access control and easy, yet secure, data sharing across centers. The reports contain DVH statistics for structures in user defined patient groups. The system currently contains over 2200 patients in 14 collaborations. Conclusions: A central RT plan repository for use in multi-center trials and quality assurance was created. The system provides an attractive alternative to dummy runs by enabling continuous monitoring of protocol conformity and plan metrics in a trial.

  8. A DICOM based radiotherapy plan database for research collaboration and reporting

    Purpose: To create a central radiotherapy (RT) plan database for dose analysis and reporting, capable of calculating and presenting statistics on user defined patient groups. The goal is to facilitate multi-center research studies with easy and secure access to RT plans and statistics on protocol compliance. Methods: RT institutions are able to send data to the central database using DICOM communications on a secure computer network. The central system is composed of a number of DICOM servers, an SQL database and in-house developed software services to process the incoming data. A web site within the secure network allows the user to manage their submitted data. Results: The RT plan database has been developed in Microsoft .NET and users are able to send DICOM data between RT centers in Denmark. Dose-volume histogram (DVH) calculations performed by the system are comparable to those of conventional RT software. A permission system was implemented to ensure access control and easy, yet secure, data sharing across centers. The reports contain DVH statistics for structures in user defined patient groups. The system currently contains over 2200 patients in 14 collaborations. Conclusions: A central RT plan repository for use in multi-center trials and quality assurance was created. The system provides an attractive alternative to dummy runs by enabling continuous monitoring of protocol conformity and plan metrics in a trial.

  9. Human health risk assessment database, 'the NHSRC toxicity value database': Supporting the risk assessment process at US EPA's National Homeland Security Research Center

    The toxicity value database of the United States Environmental Protection Agency's (EPA) National Homeland Security Research Center has been in development since 2004. The toxicity value database includes a compilation of agent property, toxicity, dose-response, and health effects data for 96 agents: 84 chemical and radiological agents and 12 biotoxins. The database is populated with multiple toxicity benchmark values and agent property information from secondary sources, with web links to the secondary sources, where available. A selected set of primary literature citations and associated dose-response data are also included. The toxicity value database offers a powerful means to quickly and efficiently gather pertinent toxicity and dose-response data for a number of agents that are of concern to the nation's security. This database, in conjunction with other tools, will play an important role in understanding human health risks, and will provide a means for risk assessors and managers to make quick and informed decisions on the potential health risks and determine appropriate responses (e.g., cleanup) to agent release. A final, stand alone MS ACESSS working version of the toxicity value database was completed in November, 2007

  10. Fine-grained policy control in U.S. Army Research Laboratory (ARL) multimodal signatures database

    Bennett, Kelly; Grueneberg, Keith; Wood, David; Calo, Seraphin

    2014-06-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) consists of a number of colocated relational databases representing a collection of data from various sensors. Role-based access to this data is granted to external organizations such as DoD contractors and other government agencies through a client Web portal. In the current MMSDB system, access control is only at the database and firewall level. In order to offer finer grained security, changes to existing user profile schemas and authentication mechanisms are usually needed. In this paper, we describe a software middleware architecture and implementation that allows fine-grained access control to the MMSDB at a dataset, table, and row level. Result sets from MMSDB queries issued in the client portal are filtered with the use of a policy enforcement proxy, with minimal changes to the existing client software and database. Before resulting data is returned to the client, policies are evaluated to determine if the user or role is authorized to access the data. Policies can be authored to filter data at the row, table or column level of a result set. The system uses various technologies developed in the International Technology Alliance in Network and Information Science (ITA) for policy-controlled information sharing and dissemination1. Use of the Policy Management Library provides a mechanism for the management and evaluation of policies to support finer grained access to the data in the MMSDB system. The GaianDB is a policy-enabled, federated database that acts as a proxy between the client application and the MMSDB system.

  11. Computer-Aided Systems Engineering for Flight Research Projects Using a Workgroup Database

    Mizukami, Masahi

    2004-01-01

    An online systems engineering tool for flight research projects has been developed through the use of a workgroup database. Capabilities are implemented for typical flight research systems engineering needs in document library, configuration control, hazard analysis, hardware database, requirements management, action item tracking, project team information, and technical performance metrics. Repetitive tasks are automated to reduce workload and errors. Current data and documents are instantly available online and can be worked on collaboratively. Existing forms and conventional processes are used, rather than inventing or changing processes to fit the tool. An integrated tool set offers advantages by automatically cross-referencing data, minimizing redundant data entry, and reducing the number of programs that must be learned. With a simplified approach, significant improvements are attained over existing capabilities for minimal cost. By using a workgroup-level database platform, personnel most directly involved in the project can develop, modify, and maintain the system, thereby saving time and money. As a pilot project, the system has been used to support an in-house flight experiment. Options are proposed for developing and deploying this type of tool on a more extensive basis.

  12. High Tech High interns develop a mid-ocean ridge database for research and education

    Staudigel, D.; Delaney, R.; Staudigel, H.; Koppers, A.; Miller, S.

    2003-04-01

    Mid-ocean ridges (MOR) represent one of the most important geographic features on planet Earth. MORs are the locations where plates spread apart, they are the locations of most of the earths' volcanoes that harbor some of the most extreme life forms. These concepts attract much research, but mid-ocean ridges are still effectively not represented in the earth science class rooms. We began an internship at Scripps to develop a database for mid-ocean ridges as a resource for science and for education. Major research goals of this project include the development of an archival structure for data, images or any other arbitrary digital objects relating to MORs, and to compile a global data set for some of the most defining characteristics of every ridge segment. One of the challenges included the need of making MOR data useful to the scientist as well as the teacher in the class room. While this data base remains a long term project, we completed a series of first order steps that establish an archival structure and lay out the defining information for each ridge segment. To create this database we used existing maps of the age of the ocean floor (University of Sidney) and the MOR locations from the University of Texas database. We divided the global MOR system into segments through their end-point coordinates, using the mid-point lat/lon as a generic name and we digitized the area of the 11 Ma isochron. Each ridge segment was also characterized with the ocean it is in, and the names of the plates. This allowed us to create a database structure for MOR segments, similar to the seamount catalogue (http://earthref.org/databases/SC/main.htm). The data compiled allow us to determine the length of the ridges, spreading rates, the ocean crust production rates, and plate motion vectors for every ridge segment, ocean or the global ocean ridge system. The process of creating this data base introduced us to the excitement of MOR research, allowing us to create a resource that is

  13. Modeling the High Speed Research Cycle 2B Longitudinal Aerodynamic Database Using Multivariate Orthogonal Functions

    Morelli, E. A.; Proffitt, M. S.

    1999-01-01

    The data for longitudinal non-dimensional, aerodynamic coefficients in the High Speed Research Cycle 2B aerodynamic database were modeled using polynomial expressions identified with an orthogonal function modeling technique. The discrepancy between the tabular aerodynamic data and the polynomial models was tested and shown to be less than 15 percent for drag, lift, and pitching moment coefficients over the entire flight envelope. Most of this discrepancy was traced to smoothing local measurement noise and to the omission of mass case 5 data in the modeling process. A simulation check case showed that the polynomial models provided a compact and accurate representation of the nonlinear aerodynamic dependencies contained in the HSR Cycle 2B tabular aerodynamic database.

  14. Aspergillus flavus Blast2GO gene ontology database: elevated growth temperature alters amino acid metabolism

    The availability of a representative gene ontology (GO) database is a prerequisite for a successful functional genomics study. Using online Blast2GO resources we constructed a GO database of Aspergillus flavus. Of the predicted total 13,485 A. flavus genes 8,987 were annotated with GO terms. The mea...

  15. High Tech High School Interns Develop a Mid-Ocean Ridge Database for Research and Education

    Staudigel, D.; Delaney, R.; Staudigel, H.; Koppers, A. A.; Miller, S. P.

    2004-12-01

    Mid-ocean ridges (MOR) represent one of the most important geographical and geological features on planet Earth. MORs are the locations where plates spread apart, they are the locations of the majority of the Earths' volcanoes that harbor some of the most extreme life forms. These concepts attract much research, but mid-ocean ridges are still effectively underrepresented in the Earth science class rooms. As two High Tech High School students, we began an internship at Scripps to develop a database for mid-ocean ridges as a resource for science and education. This Ridge Catalog will be accessible via http://earthref.org/databases/RC/ and applies a similar structure, design and data archival principle as the Seamount Catalog under EarthRef.org. Major research goals of this project include the development of (1) an archival structure for multibeam and sidescan data, standard bathymetric maps (including ODP-DSDP drill site and dredge locations) or any other arbitrary digital objects relating to MORs, and (2) to compile a global data set for some of the most defining characteristics of every ridge segment including ridge segment length, depth and azimuth and half spreading rates. One of the challenges included the need of making MOR data useful to the scientist as well as the teacher in the class room. Since the basic structure follows the design of the Seamount Catalog closely, we could move our attention to the basic data population of the database. We have pulled together multibeam data for the MOR segments from various public archives (SIOExplorer, SIO-GDC, NGDC, Lamont), and pre-processed it for public use. In particular, we have created individual bathymetric maps for each ridge segment, while merging the multibeam data with global satellite bathymetry data from Smith & Sandwell (1997). The global scale of this database will give it the ability to be used for any number of applications, from cruise planning to data

  16. Acid mine drainage research in Canada

    Acidic drainage resulting from base metal, precious metal, and uranium mining is the largest single environmental problems facing the Canadian mining industry today. Technologies to prevent acidic drainage from occurring in waste rock piles and tailings sites, and on the walls of open pits and underground mines, need to be developed and demonstrated. There are two grounds in Canada which have accepted this challenge: the national Mine Environment Neutral Drainage (MEND) program and the British Columbia Acid Mine Drainage (BC AMD) Task Force. This paper summarizes the activities of these two organizations

  17. What Do They Tell Their Students? Business Faculty Acceptance of the Web and Library Databases for Student Research

    Dewald, Nancy H.

    2005-01-01

    Business faculty were surveyed as to their use of free Web resources and subscription databases for their own and their students' research. A much higher percentage of respondents either require or encourage Web use by their students than require or encourage database use, though most also advise use of multiple sources.

  18. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    Jones, Roy; Wilkinson, David; Lopez, Oscar L; Cummings, Jeffrey; Waldemar, Gunhild; Zhang, Richard; Mackell, Joan; Gauthier, Serge

    2011-01-01

    Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical ...

  19. Construction of a bibliographic information database and development of retrieval system for research reports in nuclear science and technology (II)

    Han, Duk Haeng; Kim, Tae Whan; Choi, Kwang; Yoo, An Na; Keum, Jong Yong; Kim, In Kwon [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-05-01

    The major goal of this project is to construct a bibliographic information database in nuclear engineering and to develop a prototype retrieval system. To give an easy access to microfiche research report, this project has accomplished the construction of microfiche research reports database and the development of retrieval system. The results of the project are as follows; 1. Microfiche research reports database was constructed by downloading from DOE Energy, NTIS, INIS. 2. The retrieval system was developed in host and web version using access point such as title, abstracts, keyword, report number. 6 tabs., 8 figs., 11 refs. (Author) .new.

  20. A database of chromatographic properties and mass spectra of fatty acid methyl esters from omega-3 products.

    Wasta, Ziar; Mjøs, Svein A

    2013-07-19

    Fatty acids in products claimed to contain oils with the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were analyzed as fatty acid methyl esters by gas chromatography-mass spectrometry using electron impact ionization. To cover the variation in products on the market, the 20 products that were studied in detail were selected from a larger sample set by statistical methodology. The samples were analyzed on two different stationary phases (polyethylene glycol and cyanopropyl) and the fatty acid methyl esters were identified by methodology that combines the mass spectra and retention indices into a single score value. More that 100 fatty acids had a chromatographic area above 0.1% of the total, in at least one product. Retention indices are reported as equivalent chain lengths, and overlap patterns on the two columns are discussed. Both columns were found suitable for analysis of major and nutritionally important fatty acids, but the large number of minor compounds that may act as interferents will be problematic if low limits of quantification are required in analyses of similar sample types. A database of mass spectral libraries and equivalent chain lengths of the detected compounds has been compiled and is available online. PMID:23773584

  1. Administrative Databases in Orthopaedic Research: Pearls and Pitfalls of Big Data.

    Patel, Alpesh A; Singh, Kern; Nunley, Ryan M; Minhas, Shobhit V

    2016-03-01

    The drive for evidence-based decision-making has highlighted the shortcomings of traditional orthopaedic literature. Although high-quality, prospective, randomized studies in surgery are the benchmark in orthopaedic literature, they are often limited by size, scope, cost, time, and ethical concerns and may not be generalizable to larger populations. Given these restrictions, there is a growing trend toward the use of large administrative databases to investigate orthopaedic outcomes. These datasets afford the opportunity to identify a large numbers of patients across a broad spectrum of comorbidities, providing information regarding disparities in care and outcomes, preoperative risk stratification parameters for perioperative morbidity and mortality, and national epidemiologic rates and trends. Although there is power in these databases in terms of their impact, potential problems include administrative data that are at risk of clerical inaccuracies, recording bias secondary to financial incentives, temporal changes in billing codes, a lack of numerous clinically relevant variables and orthopaedic-specific outcomes, and the absolute requirement of an experienced epidemiologist and/or statistician when evaluating results and controlling for confounders. Despite these drawbacks, administrative database studies are fundamental and powerful tools in assessing outcomes on a national scale and will likely be of substantial assistance in the future of orthopaedic research. PMID:26836377

  2. The Corvids Literature Database--500 years of ornithological research from a crow's perspective.

    Droege, Gabriele; Töpfer, Till

    2016-01-01

    Corvids (Corvidae) play a major role in ornithological research. Because of their worldwide distribution, diversity and adaptiveness, they have been studied extensively. The aim of the Corvids Literature Database (CLD, http://www.corvids.de/cld) is to record all publications (citation format) on all extant and extinct Crows, Ravens, Jays and Magpies worldwide and tag them with specific keywords making them available for researchers worldwide. The self-maintained project started in 2006 and today comprises 8000 articles, spanning almost 500 years. The CLD covers publications from 164 countries, written in 36 languages and published by 8026 authors in 1503 journals (plus books, theses and other publications). Forty-nine percent of all records are available online as full-text documents or deposited in the physical CLD archive. The CLD contains 442 original corvid descriptions. Here, we present a metadata assessment of articles recorded in the CLD including a gap analysis and prospects for future research. Database URL: http://www.corvids.de/cld. PMID:26868053

  3. SPIN query tools for de-identified research on a humongous database.

    McDonald, Clement J; Dexter, Paul; Schadow, Gunther; Chueh, Henry C; Abernathy, Greg; Hook, John; Blevins, Lonnie; Overhage, J Marc; Berman, Jules J

    2005-01-01

    The Shared Pathology Informatics Network (SPIN), a research initiative of the National Cancer Institute, will allow for the retrieval of more than 4 million pathology reports and specimens. In this paper, we describe the special query tool as developed for the Indianapolis/Regenstrief SPIN node, integrated into the ever-expanding Indiana Network for Patient care (INPC). This query tool allows for the retrieval of de-identified data sets using complex logic, auto-coded final diagnoses, and intrinsically supports multiple types of statistical analyses. The new SPIN/INPC database represents a new generation of the Regenstrief Medical Record system - a centralized, but federated system of repositories. PMID:16779093

  4. Research Update: The materials genome initiative: Data sharing and the impact of collaborative ab initio databases

    Jain, Anubhav; Persson, Kristin A.; Ceder, Gerbrand

    2016-05-01

    Materials innovations enable new technological capabilities and drive major societal advancements but have historically required long and costly development cycles. The Materials Genome Initiative (MGI) aims to greatly reduce this time and cost. In this paper, we focus on data reuse in the MGI and, in particular, discuss the impact of three different computational databases based on density functional theory methods to the research community. We also discuss and provide recommendations on technical aspects of data reuse, outline remaining fundamental challenges, and present an outlook on the future of MGI's vision of data sharing.

  5. The Government Finance Database: A Common Resource for Quantitative Research in Public Financial Analysis.

    Pierson, Kawika; Hand, Michael L; Thompson, Fred

    2015-01-01

    Quantitative public financial management research focused on local governments is limited by the absence of a common database for empirical analysis. While the U.S. Census Bureau distributes government finance data that some scholars have utilized, the arduous process of collecting, interpreting, and organizing the data has led its adoption to be prohibitive and inconsistent. In this article we offer a single, coherent resource that contains all of the government financial data from 1967-2012, uses easy to understand natural-language variable names, and will be extended when new data is available. PMID:26107821

  6. Scientific Research Database of the 2008 Ms8.0 Wenchuan Earthquake

    Liang, C.; Yang, Y.; Yu, Y.

    2013-12-01

    Nearly 5 years after the 2008 Ms8.0 Wenchuan Earthquake, the Ms7.0 Lushan earthquake stroke 70km away along the same fault system. Given the tremendous life loss and property damages as well as the short time and distance intervals between the two large magnitude events, the scientific probing into their causing factors and future seismic activities in the nearby region will continue to be in the center of earthquake research in China and even the world for years to come. In the past five years, scientists have made significant efforts to study the Wenchuan earthquake from various aspects using different datasets and methods. Their studies cover a variety of topics including seismogenic environment, earthquake precursors, rupture process, co-seismic phenomenon, hazard relief, reservoir induced seismicity and more. These studies have been published in numerous journals in Chinese, English and many other languages. In addition, 54 books regarding to this earthquake have been published. The extremely diversified nature of all publications makes it very difficult and time-consuming, if not impossible, to sort out information needed by individual researcher in an efficient way. An information platform that collects relevant scientific information and makes them accessible in various ways can be very handy. With this mission in mind, the Earthquake Research Group in the Chengdu University of Technology has developed a website www.wceq.org to attack this target: (1) articles published by major journals and books are recorded into a database. Researchers will be able to find articles by topics, journals, publication dates, authors and keywords e.t.c by a few clicks; (2) to fast track the latest developments, researchers can also follow upon updates in the current month, last 90days, 180 days and 365 days by clicking on corresponding links; (3) the modern communication tools such as Facebook, Twitter and their Chinese counterparts are accommodated in this site to share

  7. Improving Care And Research Electronic Data Trust Antwerp (iCAREdata): a research database of linked data on out-of-hours primary care

    Colliers, Annelies; Bartholomeeusen, Stefaan; Remmen, Roy; Coenen, Samuel; Michiels, Barbara; Bastiaens, Hilde; Van Royen, Paul; Verhoeven, Veronique; Holmgren, Philip; De Ruyck, Bernard; Philips, Hilde

    2016-01-01

    Background Primary out-of-hours care is developing throughout Europe. High-quality databases with linked data from primary health services can help to improve research and future health services. Methods In 2014, a central clinical research database infrastructure was established (iCAREdata: Improving Care And Research Electronic Data Trust Antwerp, www.icaredata.eu) for primary and interdisciplinary health care at the University of Antwerp, linking data from General Practice Cooperatives, Em...

  8. National Database for Autism Research (NDAR): Big Data Opportunities for Health Services Research and Health Technology Assessment.

    Payakachat, Nalin; Tilford, J Mick; Ungar, Wendy J

    2016-02-01

    The National Database for Autism Research (NDAR) is a US National Institutes of Health (NIH)-funded research data repository created by integrating heterogeneous datasets through data sharing agreements between autism researchers and the NIH. To date, NDAR is considered the largest neuroscience and genomic data repository for autism research. In addition to biomedical data, NDAR contains a large collection of clinical and behavioral assessments and health outcomes from novel interventions. Importantly, NDAR has a global unique patient identifier that can be linked to aggregated individual-level data for hypothesis generation and testing, and for replicating research findings. As such, NDAR promotes collaboration and maximizes public investment in the original data collection. As screening and diagnostic technologies as well as interventions for children with autism are expensive, health services research (HSR) and health technology assessment (HTA) are needed to generate more evidence to facilitate implementation when warranted. This article describes NDAR and explains its value to health services researchers and decision scientists interested in autism and other mental health conditions. We provide a description of the scope and structure of NDAR and illustrate how data are likely to grow over time and become available for HSR and HTA. PMID:26446859

  9. Acid rain and related air-pollution research. A directory of USDA and state projects in CRIS. Final report

    The directory is a listing of the ongoing and recently completed research projects from the Current Research Information System (CRIS) database of the U.S. Department of Agriculture (USDA), which deal with acid rain and the related effects of air pollutants on crops and livestock. The projects were identified in March 1986, and include research active as of October 1982. The CRIS database contains projects conducted or sponsored by the USDA, State agricultural experiment stations and land-grant institutions, State forestry schools and other cooperating State institutions. CRIS is operated by the Cooperative State Research Service, USDA. Project abstracts appear in the main entry section, which is organized into chapters based upon plant, animal and natural resource categories used for classifying projects in the CRIS database. Projects assigned more than one category are repeated in each of the applicable chapters. Additional points of access are provided by a keyword/title index, investigator index, and performing institution index

  10. DMPD: Nucleic acid-sensing TLRs as modifiers of autoimmunity. [Dynamic Macrophage Pathway CSML Database

    Full Text Available 17082566 Nucleic acid-sensing TLRs as modifiers of autoimmunity. Deane JA, Bolland ...S. J Immunol. 2006 Nov 15;177(10):6573-8. (.png) (.svg) (.html) (.csml) Show Nucleic acid-sensing TLRs as modifiers of autoimmunity.... PubmedID 17082566 Title Nucleic acid-sensing TLRs as modifiers of autoimmunity. Aut

  11. Development of a Local Entomological Database for Education and Research using Simulation (Virtual Methods

    Emad I. Khater

    2014-01-01

    Full Text Available Bioinformatics has been regarded as one of the rapidly-evolving fields with enormous impact on the history of life and biomedical sciences. It is an interdisciplinary science that integrates life sciences, mathematics and computer science in order to extract meaningful biological insights from large data sets of raw DNA and protein sequences. Our objective was the development of an entomogenomics database (provisionally named EntomDB for education and research in entomology (entomology is the science of insects. This DB includes DNA/protein sequence data selected from genomes of major insect models of importance in biology and biomedical research. EntomDB will represent a customized easy, interactive and self-learning resource tool for beginner users in poor-resource settings. This will enable the users to learn basic skills in bioinformatics and genomics, needlessly to search through the numerous databases currently available on the World-Wide Web with their complex interfaces and contents. EntomDB will help students and young researchers in studying the primary structure, splicing, and translation and predict function of different genes by using simple simulation methods. It is also designed to be adaptable to work off-line, in case no internet connection is available. EntomDB is primarily designed for entomology discipline; however, it can easily be adapted for other disciplines in life and biomedical sciences. EntomDB will have important educational and developmental outcomes in promoting bioinformatics learning in the developing world and provide affordable first-level training for advanced degree and research levels.

  12. An examination of models of issue development: Environmental scanning using on-line databases: Final report. [Acid rain, PCBs, thermal pollution, ground water pollution

    Clabaugh, G.T.; Hallett, J.J.

    1987-02-01

    Examining the evolution of six environmental issues over a ten-year period, this study investigates the dominant theories of issue development and the applicability of on-line information sources to the issues management process. The research methodology used was a form of content analysis known as bibliometric analysis. Six environmental issues (acid rain, PCBs, thermal pollution, groundwater contamination, leaking underground storage tanks and leachate) were selected for a retrospective analysis of their evolution as public issues. Their evolution was tracked through the scientific, popular, legislative and national press, then compared to existing models of issue development. The research was conducted using a high-speed proprietary software program, and was based on how often the chosen issues were mentioned in selected databases. The rise and/or fall in frequency for each issue was charted and the resultant patterns were compared to theoretical models. More than 20 million articles from 24 databases were individually scanned for mentions of the issues, and efforts were made to find patterns in their growth and evolution. Charts and graphs of the results were generated and analyzed. A number of questions were raised about the use of computers and on-line information as issues management tools, plus suggestions for future research.

  13. Turning text into research networks: information retrieval and computational ontologies in the creation of scientific databases.

    Flávio Ceci

    Full Text Available BACKGROUND: Web-based, free-text documents on science and technology have been increasing growing on the web. However, most of these documents are not immediately processable by computers slowing down the acquisition of useful information. Computational ontologies might represent a possible solution by enabling semantically machine readable data sets. But, the process of ontology creation, instantiation and maintenance is still based on manual methodologies and thus time and cost intensive. METHOD: We focused on a large corpus containing information on researchers, research fields, and institutions. We based our strategy on traditional entity recognition, social computing and correlation. We devised a semi automatic approach for the recognition, correlation and extraction of named entities and relations from textual documents which are then used to create, instantiate, and maintain an ontology. RESULTS: We present a prototype demonstrating the applicability of the proposed strategy, along with a case study describing how direct and indirect relations can be extracted from academic and professional activities registered in a database of curriculum vitae in free-text format. We present evidence that this system can identify entities to assist in the process of knowledge extraction and representation to support ontology maintenance. We also demonstrate the extraction of relationships among ontology classes and their instances. CONCLUSION: We have demonstrated that our system can be used for the conversion of research information in free text format into database with a semantic structure. Future studies should test this system using the growing number of free-text information available at the institutional and national levels.

  14. TarNet: An Evidence-Based Database for Natural Medicine Research

    Ren, Guomin; Sun, Guibo; Sun, Xiaobo

    2016-01-01

    Background Complex diseases seriously threaten human health. Drug discovery approaches based on “single genes, single drugs, and single targets” are limited in targeting complex diseases. The development of new multicomponent drugs for complex diseases is imperative, and the establishment of a suitable solution for drug group-target protein network analysis is a key scientific problem that must be addressed. Herbal medicines have formed the basis of sophisticated systems of traditional medicine and have given rise to some key drugs that remain in use today. The search for new molecules is currently taking a different route, whereby scientific principles of ethnobotany and ethnopharmacognosy are being used by chemists in the discovery of different sources and classes of compounds. Results In this study, we developed TarNet, a manually curated database and platform of traditional medicinal plants with natural compounds that includes potential bio-target information. We gathered information on proteins that are related to or affected by medicinal plant ingredients and data on protein–protein interactions (PPIs). TarNet includes in-depth information on both plant–compound–protein relationships and PPIs. Additionally, TarNet can provide researchers with network construction analyses of biological pathways and protein–protein interactions (PPIs) associated with specific diseases. Researchers can upload a gene or protein list mapped to our PPI database that has been manually curated to generate relevant networks. Multiple functions are accessible for network topological calculations, subnetwork analyses, pathway analyses, and compound–protein relationships. Conclusions TarNet will serve as a useful analytical tool that will provide information on medicinal plant compound-affected proteins (potential targets) and system-level analyses for systems biology and network pharmacology researchers. TarNet is freely available at http://www.herbbol.org:8001/tarnet

  15. A Green's function database platform for seismological research and education: applications and examples

    Heimann, Sebastian; Kriegerowski, Marius; Dahm, Torsten; Simone, Cesca; Wang, Rongjiang

    2016-04-01

    The study of seismic sources from measured waveforms requires synthetic elementary seismograms (Green's functions, GF) calculated for specific earth models and source receiver geometries. Since the calculation of GFs is computationally expensive and requires careful parameter testing and quality control, pre-calculated GF databases, which can be re-used for different types of applications, can be of advantage. We developed a GF database web platform for the seismological community (http://kinherd.org/), where a researcher can share Green's function stores and retrieve synthetic seismograms on the fly for various point and extended earthquake source models for many different earth models at local, regional and global scale. This web service is part of a rich new toolset for the creation and handling of Green's functions and synthetic seismograms (http://emolch.github.com/pyrocko/gf). It can be used off-line or in client mode. We demonstrate core features of the GF platform with different applications on global, regional and local scales. These include the automatic inversion of kinematic source parameter from teleseismic body waves, the improved depth estimate of shallow induced earthquakes from regional seismological arrays, or the relative moment tensor inversion of local earthquakes from volcanic induced seismicity.

  16. Delivering research output to the user using ICT services: Marine contamination database web interface

    This project is about developing a web-based interface for accessing the Marine Contamination database records. The system contains of information pertaining to the occurrence of contaminants and natural elements in the marine eco-system based on samples taken at various locations within the shores of Malaysia in the form of sediment, seawater and marine biota. It represents a systematic approach for recording, storing and managing the vast amount of marine environmental data collected as output of the Marine Contamination and Transport Phenomena Research Project since 1990. The resultant collection of data is to form the background information (or baseline data) which could later be used to monitor the level of marine environmental pollutions around the country. Data collected from the various sampling and related laboratory activities are previously kept in conventional forms such as Excel worksheets and other documents, both in digital and/or paper form. With the help of modern database storage and retrieval techniques, the task of storage and retrieval of data has been made easier and manageable. It can also provide easy access to other parties who are interested in the data. (author)

  17. Research progress in muscle-derived stem cells Literature retrieval results based on international database

    Li Zhang; Wei Wang

    2012-01-01

    OBJECTIVE: To identify global research trends of muscle-derived stem cells (MDSCs) using a bibliometric analysis of the Web of Science, Research Portfolio Online Reporting Tools of the National Institutes of Health (NIH), and the Clinical Trials registry database (ClinicalTrials.gov). DATA RETRIEVAL: We performed a bibliometric analysis of data retrievals for MDSCs from 2002 to 2011 using the Web of Science, NIH, and ClinicalTrials.gov. MAIN OUTCOME MEASURES: (1) Type of literature; (2) annual publication output; (3) distribution according to journals; (4) distribution according to country; (5) distribution according to institution; (6) top cited authors over the last 10 years; (7) projects financially supported by the NIH; and (8) clinical trials registered.RESULTS: (1) In all, 802 studies on MDSCs appeared in the Web of Science from 2002 to 2011, almost half of which derived from American authors and institutes. The number of studies on MDSCs has gradually increased over the past 10 years. Most papers on MDSCs appeared in journals with a particular focus on cell biology research, such as Experimental Cell Research, Journal of Cell Science, and PLoS One. (2) Eight MDSC research projects have received over US$6 billion in funding from the NIH. The current project led by Dr. Johnny Huard of the University of Pittsburgh-"Muscle-Based Tissue Engineering to Improve Bone Healing"-is supported by the NIH. Dr. Huard has been the most productive and top-cited author in the field of gene therapy and adult stem cell research in the Web of Science over last 10 years. (3) On ClinicalTrials.gov, "Muscle Derived Cell Therapy for Bladder Exstrophy Epispadias Induced Incontinence" Phase 1 is registered and sponsored by Johns Hopkins University and has been led by Dr. John P. Gearhart since November 2009.CONCLUSION: From our analysis of the literature and research trends, we found that MDSCs may offer further benefits in regenerative medicine.

  18. The human studies database project: federating human studies design data using the ontology of clinical research.

    Sim, Ida; Carini, Simona; Tu, Samson; Wynden, Rob; Pollock, Brad H; Mollah, Shamim A; Gabriel, Davera; Hagler, Herbert K; Scheuermann, Richard H; Lehmann, Harold P; Wittkowski, Knut M; Nahm, Meredith; Bakken, Suzanne

    2010-01-01

    Human studies, encompassing interventional and observational studies, are the most important source of evidence for advancing our understanding of health, disease, and treatment options. To promote discovery, the design and results of these studies should be made machine-readable for large-scale data mining, synthesis, and re-analysis. The Human Studies Database Project aims to define and implement an informatics infrastructure for institutions to share the design of their human studies. We have developed the Ontology of Clinical Research (OCRe) to model study features such as design type, interventions, and outcomes to support scientific query and analysis. We are using OCRe as the reference semantics for federated data sharing of human studies over caGrid, and are piloting this implementation with several Clinical and Translational Science Award (CTSA) institutions. PMID:21347149

  19. Proyecto AVIS: a Spanish open access bird database available for research

    Sara Varela

    2014-12-01

    Full Text Available Proyecto AVIS1 is an open access citizen science database that stores information collected by amateur ornithologists about bird occurrences and abundance in Spain. Proyecto AVIS was launched in 2005 and today stores data from 415 species (ca. 90% of bird species in Spain; it covers 30% of the Spanish territory, including the Canary Islands in the Atlantic Ocean and the Balearic Islands in the Mediterranean Sea. Here, we acknowledge the work of all the volunteers that have gathered bird records in the field and uploaded these observations over the last 10 years, and introduce Proyecto AVIS to a broader community of biogeographers and macroecologists to promote its use for research

  20. Development of a database for prompt γ-ray neutron activation analysis. Summary report of the second research coordination meeting

    This report summarizes the presentations, recommendations and conclusions of the Second Research Co-ordination Meeting on Development of a Database for Prompt γ-ray Neutron Activation Analysis. The purpose of this meeting was to review results achieved on the development of the database, discuss further developments and planning of the products ol this CRP. Actions to be taken were agreed upon with the aim to complete the project by the end of 2002. (author)

  1. Workshop report: Identifying opportunities for global integration of toxicogenomics databases, 26–27 June 2013, Research Triangle Park, NC, USA

    Hendrickx, Diana M.; Boyles, Rebecca R.; Kleinjans, Jos C. S.; Dearry, Allen

    2014-01-01

    A joint US-EU workshop on enhancing data sharing and exchange in toxicogenomics was held at the National Institute for Environmental Health Sciences. Currently, efficient reuse of data is hampered by problems related to public data availability, data quality, database interoperability (the ability to exchange information), standardization and sustainability. At the workshop, experts from universities and research institutes presented databases, studies, organizations and tools that attempt to...

  2. Hydrogen bonding in oxalic acid and its complexes: A database study of neutron structures

    R Chitra; Amit Das; R R Choudhury; M Ramanadham; R Chidambaram

    2004-08-01

    The basic result of carboxylic group that the oxygen atom of the –OH never seems to be a hydrogen bond acceptor is violated in the cases, namely urea oxalic acid and bis urea oxalic acid complexes, where the hydroxyl oxygen atom is an acceptor of a weak N–H... O hydrogen bond. The parameters of this hydrogen bond, respectively in these structures are: hydrogen acceptor distance 2.110 Å and 2.127 Å and the bending angle at hydrogen, 165.6° and 165.8°. The bond strength around the hydroxyl oxygen is close to 1.91 valence units, indicating that it has hardly any strength left to form hydrogen bonds. These two structures being highly planar, force the formation of this hydrogen bond. As oxalic acid is the common moiety, the structures of the two polymorphs, -oxalic acid and -oxalic acid, also were looked into in terms of hydrogen bonding and packing.

  3. Creating a data exchange strategy for radiotherapy research: towards federated databases and anonymised public datasets.

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Büttner, Daniel; Debus, Jürgen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A; Lewensohn, Rolf; Lühr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Björn; Zips, Daniel; Baumann, Michael

    2014-12-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational models to support medical decisions (e.g. risk/benefit analysis of treatment options) represent just a fraction of the potential benefits of medical data-pooling. Distributed machine learning and knowledge exchange from federated databases can be considered as one beyond other attractive approaches for knowledge generation within "Big Data". Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning data, are deemed to be fundamental elements for large multi-centre studies in the field of radiation therapy and oncology. To fully utilise the captured medical information, the study data have to be more than just an electronic version of a traditional (un-modifiable) paper CRF. Challenges that have to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data exchange in the field of radiation therapy and oncology. PMID:25458128

  4. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational models to support medical decisions (e.g. risk/benefit analysis of treatment options) represent just a fraction of the potential benefits of medical data-pooling. Distributed machine learning and knowledge exchange from federated databases can be considered as one beyond other attractive approaches for knowledge generation within “Big Data”. Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning data, are deemed to be fundamental elements for large multi-centre studies in the field of radiation therapy and oncology. To fully utilise the captured medical information, the study data have to be more than just an electronic version of a traditional (un-modifiable) paper CRF. Challenges that have to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data exchange in the field of radiation therapy and oncology

  5. Data quality in European primary care research databases. Report of a workshop held in London September 2013

    Tate, A Rosemary; KALRA, Dipak; Boggon, Rachael; Beloff, Natalia; Puri, Shivani; Williams, Tim

    2014-01-01

    Primary care research databases provide a significant resource for health services and epidemiological research. However since data are recorded primarily for clinical care their suitability for research may vary widely according to the research application or recording practices of individual general practitioners. A methodological approach for characterising data quality is required. We describe a one-day workshop entitled “Towards a common protocol for measuring and monitoring data quality...

  6. Development of a reference database for ion beam analysis. Summary report of the first research coordination meeting

    A summary is given of the First Research Coordination Meeting on the Development of a Reference Database for Ion Beam Analysis, including background information, objectives, recommendations for measurements, and a list of tasks assigned to participants. The next research co-ordination meeting will be held in May 2007. (author)

  7. Searching biosignal databases by content and context: Research Oriented Integration System for ECG Signals (ROISES).

    Kokkinaki, Alexandra; Chouvarda, Ioanna; Maglaveras, Nicos

    2012-11-01

    Technological advances in textile, biosensor and electrocardiography domain induced the wide spread use of bio-signal acquisition devices leading to the generation of massive bio-signal datasets. Among the most popular bio-signals, electrocardiogram (ECG) possesses the longest tradition in bio-signal monitoring and recording, being a strong and relatively robust signal. As research resources are fostered, research community promotes the need to extract new knowledge from bio-signals towards the adoption of new medical procedures. However, integrated access, query and management of ECGs are impeded by the diversity and heterogeneity of bio-signal storage data formats. In this scope, the proposed work introduces a new methodology for the unified access to bio-signal databases and the accompanying metadata. It allows decoupling information retrieval from actual underlying datasource structures and enables transparent content and context based searching from multiple data resources. Our approach is based on the definition of an interactive global ontology which manipulates the similarities and the differences of the underlying sources to either establish similarity mappings or enrich its terminological structure. We also introduce ROISES (Research Oriented Integration System for ECG Signals), for the definition of complex content based queries against the diverse bio-signal data sources. PMID:21397354

  8. Groundwater restoration research of acid ISL in China

    Based on the research on groundwater restoration of acid in situ leach mining project in West of China, development of groundwater restoration research in China is shown. The restoration test results demonstrate that Electrodialysis reversal (EDR) is an effective method for groundwater restoration. The plan of in-situ leach groundwater restoration is shown in this study also. (author)

  9. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers,Asian Agricultural Research eventually passes the extremely strict appraisal,to be indexed by CABI’ s full text repository.CABI is globally acclaimed as one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry.Since inception of publication,Asian Agricultural Research has also been indexed by AGE Database,Naresuan University Library,Rural Development Foundation of India,Royal Tropical Institute and CSA Illumina.Editorial office of Asian Agricultural Research CABI Database CABI Database,one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry,is compiled by Centre for Agricultural Bioscience International.This data base,since 1973,has indexed 5

  10. NOAA's Integrated Tsunami Database: Data for improved forecasts, warnings, research, and risk assessments

    Stroker, Kelly; Dunbar, Paula; Mungov, George; Sweeney, Aaron; McCullough, Heather; Carignan, Kelly

    2015-04-01

    The National Oceanic and Atmospheric Administration (NOAA) has primary responsibility in the United States for tsunami forecast, warning, research, and supports community resiliency. NOAA's National Geophysical Data Center (NGDC) and co-located World Data Service for Geophysics provide a unique collection of data enabling communities to ensure preparedness and resilience to tsunami hazards. Immediately following a damaging or fatal tsunami event there is a need for authoritative data and information. The NGDC Global Historical Tsunami Database (http://www.ngdc.noaa.gov/hazard/) includes all tsunami events, regardless of intensity, as well as earthquakes and volcanic eruptions that caused fatalities, moderate damage, or generated a tsunami. The long-term data from these events, including photographs of damage, provide clues to what might happen in the future. NGDC catalogs the information on global historical tsunamis and uses these data to produce qualitative tsunami hazard assessments at regional levels. In addition to the socioeconomic effects of a tsunami, NGDC also obtains water level data from the coasts and the deep-ocean at stations operated by the NOAA/NOS Center for Operational Oceanographic Products and Services, the NOAA Tsunami Warning Centers, and the National Data Buoy Center (NDBC) and produces research-quality data to isolate seismic waves (in the case of the deep-ocean sites) and the tsunami signal. These water-level data provide evidence of sea-level fluctuation and possible inundation events. NGDC is also building high-resolution digital elevation models (DEMs) to support real-time forecasts, implemented at 75 US coastal communities. After a damaging or fatal event NGDC begins to collect and integrate data and information from many organizations into the hazards databases. Sources of data include our NOAA partners, the U.S. Geological Survey, the UNESCO Intergovernmental Oceanographic Commission (IOC) and International Tsunami Information Center

  11. Copernicus benefits the Norwegian Satellite Earth Observation Database for Marine and Polar Research

    Korosov, Anton; Johannessen, Johnny

    2014-05-01

    The Norwegian Satellite Earth Observation Database for Marine and Polar Research (NORMAP) is developed for creating and maintaining a repository of Earth Observation data over the high latitude and Arctic regions to facilitate, stimulate and strengthen high quality and original multidisciplinary Earth System research, application, exploitation and education in marine, polar and climate sciences. As such it is complementing and supporting the Norwegian strategy for advancing these science disciplines in the high latitude and Arctic regions. In the international arena, NORMAP benefits and complements the EU GMES MyOcean project, and other previous GMES downstream services such as AQUAMAR, MONARCH-A, SIDARUS, etc. With the launch of the first Sentinel-1 mission NORMAP will be reinforced by the new data flow from the Copernicus Space Component. NORMAP is also acquiring data from a multitude of other satellites through the unified Copernicus system and will become one of the national thematic information services designed to benefit the environmental monitoring and support effective policy-making.

  12. Food-pics: an image database for experimental research on eating and appetite

    Jens eBlechert

    2014-06-01

    Full Text Available Our current environment is characterized by the omnipresence of food cues. The sight and smell of real foods, but also graphically depictions of appetizing foods, can guide our eating behavior, for example, by eliciting food craving and influencing food choice. The relevance of visual food cues on human information processing has been demonstrated by a growing body of studies employing food images across the disciplines of psychology, medicine, and neuroscience. However, currently used food image sets vary considerably across laboratories and image characteristics (contrast, brightness, etc. and food composition (calories, macronutrients, etc. are often unspecified. These factors might have contributed to some of the inconsistencies of this research. To remedy this, we developed food-pics, a picture database comprising 568 food images and 315 non-food images along with detailed meta-data. A total of N = 1988 individuals with large variance in age and weight from German speaking countries and North America provided normative ratings of valence, arousal, palatability, desire to eat, recognizability and visual complexity. Furthermore, data on macronutrients (g, energy density (kcal, and physical image characteristics (color composition, contrast, brightness, size, complexity are provided. The food-pics image data base is freely available under the creative commons license with the hope that the set will facilitate standardization and comparability across studies and advance experimental research on the determinants of eating behavior.

  13. Database and Registry Research in Orthopaedic Surgery: Part 2: Clinical Registry Data.

    Pugely, Andrew J; Martin, Christopher T; Harwood, Jared; Ong, Kevin L; Bozic, Kevin J; Callaghan, John J

    2015-11-01

    The use of large-scale national databases for observational research in orthopaedic surgery has grown substantially in the last decade, and the data sets can be categorized as either administrative claims or clinical registries. Clinical registries contain secondary data on patients with a specific diagnosis or procedure. The data are typically used for patient outcome surveillance to improve patient safety and health-care quality. Registries used in orthopaedic research exist at the regional, national, and international levels, and many were designed to specifically collect outcomes relevant to orthopaedics, such as short-term surgical complications, longer-term outcomes (implant survival or reoperations), and patient-reported outcomes. Although heterogeneous, clinical registries-in contrast to claims data-typically have a more robust list of variables, with relatively precise prospective data input, management infrastructure, and reporting systems. Some weaknesses of clinical registries include a smaller number of patients, inconstant follow-up duration, and use of sampling methods that may limit generalizability. Within the U.S., national joint registry adoption has lagged international joint registries. Given the changing health-care environment, it is likely that clinical registries will provide valuable information that has the potential to influence clinical practice improvement and health-care policy in the future. PMID:26537168

  14. Research on Activators for Lead-Acid Batteries

    Sugawara, Michio; Kozawa, Akiya

    2008-01-01

    Abstract : The ITE Battery Research group has developed a new organic battery activator for new and used lead-acid batteries. Ten years of investigation have established the validity of the ITE activator that prolongs the useful life of lead-acid batteries. It has been shown that the specific gravity of spent batteries can be restored to the original level in automotive, motive power; uninterruptible power supplies (UPS) and stationary energy storage batteries. Our results show that the disca...

  15. Nucleic Acid Aptamers: Research Tools in Disease Diagnostics and Therapeutics

    Baby Santosh; Pramod K. Yadava

    2014-01-01

    Aptamers are short sequences of nucleic acid (DNA or RNA) or peptide molecules which adopt a conformation and bind cognate ligands with high affinity and specificity in a manner akin to antibody-antigen interactions. It has been globally acknowledged that aptamers promise a plethora of diagnostic and therapeutic applications. Although use of nucleic acid aptamers as targeted therapeutics or mediators of targeted drug delivery is a relatively new avenue of research, one aptamer-based drug “Ma...

  16. Research and application of ORACLE performance optimizing technologies for building airplane environment resource database

    Zhang, Jianjun; Sun, Jianyong; Cheng, Conggao

    2013-03-01

    Many problems exist in processing experimental aircraft vibration (temperature, humidity) data and generating the intermediate calculations during the construction of airplane environment resource database, such as the need to deal with both structural and non-structural data, weak capacity of the client browser for data processing and massive network data transferring etc. To solve the above problems, some strategies on tuning and optimization performance of database are employed base on Oracle11g, which include data storage structure tuning, the memory configuration of the server, the disk I/O tuning and SQL statement tuning. The experimental results show that the performance of airplane environment resource database is enhanced about 80% compared with the database developed in the initial demonstration and validation phase. The application of new optimization strategies to the database construction can lay a sound foundation for finishing building airplane environment resource database.

  17. Free access to INIS database provides a gateway to nuclear energy research results

    Free access to INIS database was opened to all the Internet users around the world on May, 2009. The article reviews the history of INIS (the International Nuclear Information System), data aquisition process, database content and search possibilities. INIS is focused on the worldwide literature of the peaceful uses of nuclear energy and the database is produced in close collaboration with the IEA/ETDE World Energy Base (ETDEWEB), a database focusing on all aspects of energy. Nuclear Science Abstracts database (NSA), which is a comprehensive collection of international nuclear science and technology literature for the period 1948 through 1976, is also briefly discussed in the article. In Finland, the recently formed Aalto University is responsible for collecting and disseminating information (literature) and for the preparation of input to the INIS and IEA/ETDE Databases on the national level

  18. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    Jones, Roy; Wilkinson, David; Lopez, Oscar L;

    2011-01-01

    Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical...... community because of concerns that commercial, rather than scientific, goals are the primary purpose of such endeavours. Thus, there are few examples of sustained collaboration between leading academic clinical researchers and industry professionals in a large-scale data mining project. We present here a...

  19. Healthcare Databases in Thailand and Japan: Potential Sources for Health Technology Assessment Research

    Saokaew, Surasak; Sugimoto, Takashi; Kamae, Isao; Pratoomsoot, Chayanin; Chaiyakunapruk, Nathorn

    2015-01-01

    Background Health technology assessment (HTA) has been continuously used for value-based healthcare decisions over the last decade. Healthcare databases represent an important source of information for HTA, which has seen a surge in use in Western countries. Although HTA agencies have been established in Asia-Pacific region, application and understanding of healthcare databases for HTA is rather limited. Thus, we reviewed existing databases to assess their potential for HTA in Thailand where ...

  20. RDD Databases

    National Oceanic and Atmospheric Administration, Department of Commerce — This database was established to oversee documents issued in support of fishery research activities including experimental fishing permits (EFP), letters of...

  1. The research of network database security technology based on web service

    Meng, Fanxing; Wen, Xiumei; Gao, Liting; Pang, Hui; Wang, Qinglin

    2013-03-01

    Database technology is one of the most widely applied computer technologies, its security is becoming more and more important. This paper introduced the database security, network database security level, studies the security technology of the network database, analyzes emphatically sub-key encryption algorithm, applies this algorithm into the campus-one-card system successfully. The realization process of the encryption algorithm is discussed, this method is widely used as reference in many fields, particularly in management information system security and e-commerce.

  2. 5-Aminosalicylic acid dependency in Crohn's disease: A Danish Crohn Colitis Database study

    Duricova, D.; Pedersen, N.; Elkjaer, M.;

    2010-01-01

    Background and aims The role of 5 aminosalicylic acid (5 ASA) in Crohns disease is unclear The outcome of the first course of 5 ASA monotherapy with emphasis on 5 ASA dependency was retrospectively assessed in consecutive cohort of 537 Crohn s disease patients diagnosed 1953-2007 Methods Following...

  3. CottonGen: a genomics, genetics and breeding database for cotton research

    CottonGen (http://www.cottongen.org) is a curated and integrated web-based relational database providing access to publicly available genomic, genetic and breeding data for cotton. CottonGen supercedes CottonDB and the Cotton Marker Database, with enhanced tools for easier data sharing, mining, vis...

  4. The Research Potential of the Electronic OED Database at the University of Waterloo: A Case Study.

    Berg, Donna Lee

    1991-01-01

    Discusses the history and structure of the online database of the second edition of the Oxford English Dictionary (OED) and the software tools developed at the University of Waterloo to manipulate the unusually complex database. Four sample searches that indicate some types of problems that might be encountered are appended. (DB)

  5. FishPathogens.eu a new database in the research of aquatic animal diseases

    Jonstrup, Søren Peter; Gray, T.; Olesen, Niels Jørgen

    We live in a world where the amount of information available is enormous. In order to keep track of the available knowledge, databases are needed to collect, store, and sort it. Www.fishpathogens.eu is a database developed and maintained by the European Union Reference Laboratory for Fish Disease...

  6. Patterns of Undergraduates' Use of Scholarly Databases in a Large Research University

    Mbabu, Loyd Gitari; Bertram, Albert; Varnum, Ken

    2013-01-01

    Authentication data was utilized to explore undergraduate usage of subscription electronic databases. These usage patterns were linked to the information literacy curriculum of the library. The data showed that out of the 26,208 enrolled undergraduate students, 42% of them accessed a scholarly database at least once in the course of the entire…

  7. LLNL Middle East and North Africa and Former Soviet Union Research Database

    O' Boyle, J.L.; Ruppert, S.D.; Hauk, T.F.; Dodge, D.; Firpo, M.

    2000-07-14

    The Lawrence Livermore National Laboratory (LLNL) Ground-Based Nuclear Explosion Monitoring (GNEM) R and D program has made significant progress populating a comprehensive Seismic Research knowledge Base (SRKB) and deriving calibration parameters for the Middle East and North Africa (ME/NA) and Former Soviet Union (FSU) regions. The LLNL SRKB provides not only a coherent framework in which to store and organize very large volumes of collected seismic waveforms, associated event parameter information, and spatial contextual data, but also provides an efficient data processing/research environment for deriving location and discrimination correction surfaces. The SRKB is a flexible and extensible framework consisting of a relational database (RDB), Geographical Information System (GIS), and associated product/data visualization and data management tools. This SRKB framework is designed to accommodate large volumes of data (over 2 million waveforms from 20,000 events) in diverse formats from many sources in addition to maintaining detailed quality control and metadata. Using the SRKB framework, they are combining travel-time observations, event characterization studies, and regional tectonic models to assemble a library of ground truth information and phenomenology correction surfaces required for support of the ME/NA and FSU regionalization program. Corrections and parameters distilled from the LLNL SRKB provide needed contributions to the DOE Knowledge Base (DOE KB) for the ME/NA and FSU regions and will help improve monitoring for underground nuclear testing. The LLNL research products will facilitate calibration of IMS stations (primary and auxiliary), their surrogates (if not yet installed) and selected gamma stations necessary to complete the above tasks in the ME/NA and FSU regions. They present expanded lookup tables for critical station parameter information (including location and response) and a new integrated and reconciled event catalog dataset including

  8. Database Description - PLACE | LSDB Archive [Life Science Database Archive metadata

    Full Text Available elements (A preliminary report) Author name(s): Kenichi Higo*, Yoshihiro Ugawa and Masao Iwamoto Journal: 5... Yoshihiro Ugawa, Masao Iwamoto and Hiromi Higo Journal: Nucleic Acids Research, 1998, Vol.26, No.1 :358-359...E) database: 1999 Author name(s): Kenichi Higo*, Yoshihiro Ugawa, Masao Iwamoto and Tomoko Korenaga Journal:

  9. Researches on Cartographic Database-Based Interactive Three-Dimensional Topographic Map

    Jiang Wenping; Xi Daping

    2003-01-01

    With the development of computer graphics, the three-dimensional (3D) visualization brings new technological revolution to the traditional cartography. Therefore, the topographic 3D-map emerges to adapt to this technological revolution, and the applications of topographic 3D-map are spread rapidly to other relevant fields due to its incomparable advantage. The researches on digital map and the construction of map database offer strong technical support and abundant data source for this new technology, so the research and development of topographic 3D-map will receive greater concern. The basic data of the topographic 3D-map are rooted mainly in digital map and its basic model is derived from digital elevation model (DEM) and 3D-models of other DEM-based geographic features. In view of the potential enormous data and the complexity of geographic features, the dynamic representation of geographic information becomes the focus of the research of topographic 3D-map and also the prerequisite condition of 3D query and analysis. In addition to the equipment of hardware that are restraining, to a certain extent, the 3D representation, the data organization structure of geographic information will be the core problem of research on 3D-map. Level of detail (LOD), space partitioning, dynamic object loading (DOL) and object culling are core technologies of the dynamic 3D representation. The objectselection, attribute-query and model-editing are important functions and interaction tools for users with 3D-maps provided by topographic 3D-map system, all of which are based on the data structure of the 3Dmodel. This paper discusses the basic theories, concepts and cardinal principles of topographic 3D-map,expounds the basic way to organize the scene hierarchy of topographic 3D-map based on the node mechanism and studies the dynamic representation technologies of topographic 3D-map based on LOD, space partitioning, DOL and object culling. Moreover, such interactive operation

  10. Development and application of characteristic database for uranium mining and metallurgy in the library of Beijing Research Institute of Chemical Engineering and Metallurgy

    Beijing Research Institute of Chemical Engineering and Metallurgy (BRICEM) is a multi disciplinary comprehensive research institute engaged in uranium mining, engineering design and related material researches. After 53 years of researches and development, BRICEM has accumulated a plenty of valuable data and resources. By analyzing the actual conditions of BRICEM's technological database, this thesis aims to propose the idea of building a characteristic database for uranium mining and metallurgy. It gives an in-depth analysis on content design, development status and problems of database development, in order to come up with solutions to these problems, as well as suggestions on the future development plans of the characteristic database. (author)

  11. The Nordic prescription databases as a resource for pharmacoepidemiological research-a literature review

    Wettermark, B; Zoëga, H; Furu, K;

    2013-01-01

    PURPOSE: All five Nordic countries have nationwide prescription databases covering all dispensed drugs, with potential for linkage to outcomes. The aim of this review is to present an overview of therapeutic areas studied and methods applied in pharmacoepidemiologic studies using data from these...... databases. METHODS: The study consists of a Medline-based structured literature review of scientific papers published during 2005-2010 using data from the prescription databases in Denmark, Finland, Iceland, Norway, and Sweden, covering 25 million inhabitants. Relevant studies were analyzed in terms of...

  12. The Method of Analysis Derived Coefficients of Database as a New Method of Historical Research (for Example, a Database of Ballistic Parameters of Naval Artillery

    Nicholas W. Mitiukov

    2015-12-01

    Full Text Available In paper there is proposed a new method of historical research, based on analysis of derivatives coefficients of database (for example, the form factor in the database of ballistic data. This method has a much greater protection from subjectivism and direct falsification, compared with the analysis obtained directly from the source of the numerical series, as any intentional or unintentional distortion of the raw data provides a significant contrast ratio derived from the average sample values. Application of this method to the analysis of ballistic data base of naval artillery allowed to find the facts, forcing a new look at some of the events in the history data on the German naval artillery before World War I, probably overpriced for disinformation opponents of the Entente; during the First World War, Spain, apparently held secret talks with the firm Bofors ended purchase of Swedish shells; the first Russian naval rifled guns were created obvious based on the project Blackly, not Krupp as traditionally considered.

  13. Asian Agricultural Research is indexed by CABI, CSA Illumina, AGE and other famous databases in many countries

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry. Since inception of publication, Asian Agricultural Research has also been indexed by AGE Database, Naresuan University Library, Rural Development Foundation of India, Royal Tropical Institute and CSA lllumina.

  14. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most author-itative and prestigious abstract data bases concerning agriculture and forestry. Since inception of publication, Asian Agri-cultural Research has also been indexed by AGE Database, Naresuan University Library, Rural Development Foundation of India, Royal Tropical Institute and CSA Illumina.

  15. Summary Report of 1st Research Coordination Meeting on Development of Reference Database for Beta-delayed Neutron Emission

    A summary is given of the 1st Research Coordination Meeting of the new IAEA Coordinated Research Project (CRP) on Development of a Reference Database for Beta-delayed neutron emission data. Participants presented their work, reviewed the current status of the field with regards to individual precursors and aggregate data, and discussed the scope of the work to be undertaken. A list of priorities and task assignments was produced. (author)

  16. The Aspergillus Genome Database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community

    Arnaud, Martha B.; Chibucos, Marcus C; Costanzo, Maria C.; Crabtree, Jonathan; Inglis, Diane O.; Lotia, Adil; Orvis, Joshua; Shah, Prachi; Skrzypek, Marek S.; Binkley, Gail; Miyasato, Stuart R.; Wortman, Jennifer R.; Sherlock, Gavin

    2009-01-01

    The Aspergillus Genome Database (AspGD) is an online genomics resource for researchers studying the genetics and molecular biology of the Aspergilli. AspGD combines high-quality manual curation of the experimental scientific literature examining the genetics and molecular biology of Aspergilli, cutting-edge comparative genomics approaches to iteratively refine and improve structural gene annotations across multiple Aspergillus species, and web-based research tools for accessing and exploring ...

  17. Existing data sources for clinical epidemiology: The clinical laboratory information system (LABKA research database at Aarhus University, Denmark

    Grann AF

    2011-04-01

    Full Text Available Anne Fia Grann, Rune Erichsen, Anders Gunnar Nielsen, Trine Frøslev, Reimar W ThomsenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkAbstract: This paper provides an introduction to the clinical laboratory information system (LABKA research database in Northern and Central Denmark. The database contains millions of stored laboratory test results for patients living in the two Danish regions, encompassing 1.8 million residents, or one-third of the country's population. More than 1700 different types of blood test analyses are available. Therefore, the LABKA research database represents an incredible source for studies involving blood test analyses. By record linkage of different Danish registries with the LABKA research database, it is possible to examine a large number of biomarkers as predictors of disease risk and prognosis and as markers of disease severity, and to evaluate medical treatments regarding effectiveness and possible side effects. Large epidemiological studies using routinely stored blood test results for individual patients can be performed because it is possible to link the laboratory data to high-quality individual clinical patient data in Denmark.Keywords: biochemistry, laboratory procedures, diagnosis, therapeutic drug monitoring, epidemiological methods, registries

  18. Amino acid sequences of predicted proteins and their annotation for 95 organism species. - Gclust Server | LSDB Archive [Life Science Database Archive metadata

    Full Text Available Gclust Server Amino acid sequences of predicted proteins and their annotation for 95 organism species. Data ...detail Data name Amino acid sequences of predicted proteins and their annotation for 95 organism species. De...scription of data contents Amino acid sequences of predicted proteins and their a...nnotation for 95 organism species. The data are given in a CSV format text file. Data file File name: gclust...tation in original database Annotation at the original website Species Species name Length Amino acid sequen

  19. ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes

    Novichkov, Pavel S.; Ratnere, Igor; Wolf, Yuri I.; Koonin, Eugene V.; Dubchak, Inna

    2009-07-23

    The database of Alignable Tight Genomic Clusters (ATGCs) consists of closely related genomes of archaea and bacteria, and is a resource for research into prokaryotic microevolution. Construction of a data set with appropriate characteristics is a major hurdle for this type of studies. With the current rate of genome sequencing, it is difficult to follow the progress of the field and to determine which of the available genome sets meet the requirements of a given research project, in particular, with respect to the minimum and maximum levels of similarity between the included genomes. Additionally, extraction of specific content, such as genomic alignments or families of orthologs, from a selected set of genomes is a complicated and time-consuming process. The database addresses these problems by providing an intuitive and efficient web interface to browse precomputed ATGCs, select appropriate ones and access ATGC-derived data such as multiple alignments of orthologous proteins, matrices of pairwise intergenomic distances based on genome-wide analysis of synonymous and nonsynonymous substitution rates and others. The ATGC database will be regularly updated following new releases of the NCBI RefSeq. The database is hosted by the Genomics Division at Lawrence Berkeley National laboratory and is publicly available at http://atgc.lbl.gov.

  20. THE BUILDING OF THE SPATIAL DATABASE OF THE SATCHINEZ ORNITHOLOGICAL RESERVE AS A PREMISE OF MODERN ECOLOGICAL RESEARCH

    M. Török-Oance

    2005-01-01

    Full Text Available The creation of a database for the Ornithological Reserve “The Satchinez Marshes” was a necessity for a modern and complex ecological research. This database offers the possibility of a precise localization of the species of plants and animals identified in the field and it is a genuine base for the identification of the main types of habitats and ecosystems in the reserve. With the help of the Terrain Numerical Model, the analysis, at the level of pixels, of the abiotical factors involved in the repartition of ecosystems was made possible, as well as the three-dimensions visualizations of all the results. With the help of the aerophotograms taken in 1963 and 1973, we reconstructed the situation of the reserve at that time, by creating a database of the terrain usage at that time. The same thing was done in 2004, using more diverse sources: cadastral planes, images taken from the satellite, air photos taken in the same year and last, but not least, data collected in the field in 2003-2004. At the same time, this database can be considered a bench-mark (for the year 2004 for the identification of the modifications that occurred during 1963 and 2004, but for future research as well.

  1. RESEARCH ON HLR MOBILITY DATABASE FAILURE RECOVERY AND PERFORMANCE ANALYSIS FOR CDMA2000 SYSTEMS

    Liu Caixia; Yu Dingjiu; Cheng Dongnian; Tang Hongbo; Wu Jiangxing

    2004-01-01

    In this paper, a novel Home Location Register(HLR) mobility database recovery scheme is proposed. With database backing-up and signal sending as its key processes, the presented scheme is designed for the purpose of both decreasing system costs and reducing number of lost calls. In our scheme, an algorithm is developed for an HLR to identify such VLRs that there are new MSs roaming into them since the latest HLR database backing up. The identification of those VLRs is used by the HLR to send Unreliable Roaming Data Directive messages to each of them to get the correct location information of those new MSs. Additionally, two kinds of relationships, one between the number of lost calls and the database backing-up period and the other between the backing-up cost and the period, are well analyzed. Both analytical and numerical results indicate that there will be an optimal HLR database backing-up period if certain system parameters are given and the total cost can be consequently minimized.

  2. Workshop report: Identifying opportunities for global integration of toxicogenomics databases, 26-27 June 2013, Research Triangle Park, NC, USA.

    Hendrickx, Diana M; Boyles, Rebecca R; Kleinjans, Jos C S; Dearry, Allen

    2014-12-01

    A joint US-EU workshop on enhancing data sharing and exchange in toxicogenomics was held at the National Institute for Environmental Health Sciences. Currently, efficient reuse of data is hampered by problems related to public data availability, data quality, database interoperability (the ability to exchange information), standardization and sustainability. At the workshop, experts from universities and research institutes presented databases, studies, organizations and tools that attempt to deal with these problems. Furthermore, a case study showing that combining toxicogenomics data from multiple resources leads to more accurate predictions in risk assessment was presented. All participants agreed that there is a need for a web portal describing the diverse, heterogeneous data resources relevant for toxicogenomics research. Furthermore, there was agreement that linking more data resources would improve toxicogenomics data analysis. To outline a roadmap to enhance interoperability between data resources, the participants recommend collecting user stories from the toxicogenomics research community on barriers in data sharing and exchange currently hampering answering to certain research questions. These user stories may guide the prioritization of steps to be taken for enhancing integration of toxicogenomics databases. PMID:25326818

  3. Design and utilization of a Flight Test Engineering Database Management System at the NASA Dryden Flight Research Facility

    Knighton, Donna L.

    1992-01-01

    A Flight Test Engineering Database Management System (FTE DBMS) was designed and implemented at the NASA Dryden Flight Research Facility. The X-29 Forward Swept Wing Advanced Technology Demonstrator flight research program was chosen for the initial system development and implementation. The FTE DBMS greatly assisted in planning and 'mass production' card preparation for an accelerated X-29 research program. Improved Test Plan tracking and maneuver management for a high flight-rate program were proven, and flight rates of up to three flights per day, two times per week were maintained.

  4. Research on Optimization of Oracle Database%Oracle数据库系统优化调整

    刘超; 张明安

    2014-01-01

    在过去的几十年中,OracIe 数据库已经逐渐成为世界上最为广泛的大型数据库管理系统。而数据库 DBA的重要工作就是要确保利用 OracIe 的强大特性来提高企业的生产力。其中最有效的方法就是通过 OracIe 调优,它有大量的调整参数和技术来改进 OracIe 数据库的性能。文章从数据库内存参数调整、索引技术、数据库分区以及SQL 语句的优化等四个方面来研究 OracIe 数据库的性能调整。%In the past few decades, Oracle database has become the world's large database management system. The important work of DBA is to ensure that the use of the powerful features of Oracle and improve their productivity. One of the most ef ective ways is through the Oracle tuning. Certainly, the performance of Oracle database can be improved through a large number of parameters and technology. The article explains the things from Database memory parameter adjustment,index technology,database partition, and SQL statement optimization etc onthe performance optimization of Oracle database.

  5. Oracle数据库死锁问题研究%Research on Deadlock of Oracle Database

    姜文; 刘立康

    2014-01-01

    数据库是网络环境下多用户使用的共享资源,数据库在处理多线程大量数据存取过程中很可能出现死锁现象。文中介绍了Oracle数据库锁机制和死锁发生的原因,Oracle数据库检测死锁采用的相关视图。详细叙述了SQL语句检测死锁、死锁的定位方法和解决数据库死锁的方法。编写了在Linux环境中死锁检测脚本,模拟Oracle数据库死锁测试了脚本的正确性。实际应用表明该方法可以有效监测程序中的主要模块是否发生死锁,而且简单有效。%The database is a shared resource of multi-user in network environment,database deadlock phenomenon is likely to occur in multi-threaded process by large amounts of data access. Introduce the Oracle database locking mechanism and the causes the deadlock oc-curs,the Oracle database detects the related views deadlock uses. A detailed description is conducted for the SQL states the deadlock de-tection,the positioning method of deadlock and the resolution of the database deadlock. Compiled the deadlock detection script in the Linux environment,simulate the Oracle database deadlock to test the correctness of the script. Practical application shows that the script can be effective monitoring whether the program's main module is deadlock or not,with simplicity and effectiveness.

  6. SU-E-P-26: Oncospace: A Shared Radiation Oncology Database System Designed for Personalized Medicine, Decision Support, and Research

    Purpose: Advancement in Radiation Oncology (RO) practice develops through evidence based medicine and clinical trial. Knowledge usable for treatment planning, decision support and research is contained in our clinical data, stored in an Oncospace database. This data store and the tools for populating and analyzing it are compatible with standard RO practice and are shared with collaborating institutions. The question is - what protocol for system development and data sharing within an Oncospace Consortium? We focus our example on the technology and data meaning necessary to share across the Consortium. Methods: Oncospace consists of a database schema, planning and outcome data import and web based analysis tools.1) Database: The Consortium implements a federated data store; each member collects and maintains its own data within an Oncospace schema. For privacy, PHI is contained within a single table, accessible to the database owner.2) Import: Spatial dose data from treatment plans (Pinnacle or DICOM) is imported via Oncolink. Treatment outcomes are imported from an OIS (MOSAIQ).3) Analysis: JHU has built a number of webpages to answer analysis questions. Oncospace data can also be analyzed via MATLAB or SAS queries.These materials are available to Consortium members, who contribute enhancements and improvements. Results: 1) The Oncospace Consortium now consists of RO centers at JHU, UVA, UW and the University of Toronto. These members have successfully installed and populated Oncospace databases with over 1000 patients collectively.2) Members contributing code and getting updates via SVN repository. Errors are reported and tracked via Redmine. Teleconferences include strategizing design and code reviews.3) Successfully remotely queried federated databases to combine multiple institutions’ DVH data for dose-toxicity analysis (see below – data combined from JHU and UW Oncospace). Conclusion: RO data sharing can and has been effected according to the Oncospace

  7. SU-E-P-26: Oncospace: A Shared Radiation Oncology Database System Designed for Personalized Medicine, Decision Support, and Research

    Bowers, M; Robertson, S; Moore, J; Wong, J; DeWeese, T; McNutt, T [Johns Hopkins University, Baltimore, MD (United States); Phillips, M [Univ Washington, Seattle, WA (United States); Hendrickson, K [University of Washington, Seattle, WA (United States); Song, W; Kwok, P [Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, U of T, Toronto, Ontario (Canada)

    2015-06-15

    Purpose: Advancement in Radiation Oncology (RO) practice develops through evidence based medicine and clinical trial. Knowledge usable for treatment planning, decision support and research is contained in our clinical data, stored in an Oncospace database. This data store and the tools for populating and analyzing it are compatible with standard RO practice and are shared with collaborating institutions. The question is - what protocol for system development and data sharing within an Oncospace Consortium? We focus our example on the technology and data meaning necessary to share across the Consortium. Methods: Oncospace consists of a database schema, planning and outcome data import and web based analysis tools.1) Database: The Consortium implements a federated data store; each member collects and maintains its own data within an Oncospace schema. For privacy, PHI is contained within a single table, accessible to the database owner.2) Import: Spatial dose data from treatment plans (Pinnacle or DICOM) is imported via Oncolink. Treatment outcomes are imported from an OIS (MOSAIQ).3) Analysis: JHU has built a number of webpages to answer analysis questions. Oncospace data can also be analyzed via MATLAB or SAS queries.These materials are available to Consortium members, who contribute enhancements and improvements. Results: 1) The Oncospace Consortium now consists of RO centers at JHU, UVA, UW and the University of Toronto. These members have successfully installed and populated Oncospace databases with over 1000 patients collectively.2) Members contributing code and getting updates via SVN repository. Errors are reported and tracked via Redmine. Teleconferences include strategizing design and code reviews.3) Successfully remotely queried federated databases to combine multiple institutions’ DVH data for dose-toxicity analysis (see below – data combined from JHU and UW Oncospace). Conclusion: RO data sharing can and has been effected according to the Oncospace

  8. Active Databases & Their Research Status%主动数据库及其研究现状

    梁雯

    2001-01-01

    The similarities and differences between an active database and a traditional database are expounded. The general model of an active database and the model of the Active Database Management System are discussed. In the light of the deficiencies of the object-oriented database, the paper probes into the superiorities of combining the active database with the object-oriented database. It also discusses the present situation and the development of the active database as well as the problems to be solved.

  9. The Operational Parameter Electronic Database of the IPR-R1 TRIGA Research Reactor

    in a historical database. In every operation of the research reactor about forty variables are registered by the data acquisition system. The system provides data for the last five years (since 2004)

  10. Patient-related risk factors for fracture-healing complications in the United Kingdom General Practice Research Database

    HERNANDEZ, ROHINI K.; Do, Thy P.; Critchlow, Cathy W; Dent, Ricardo E.; Jick, Susan S

    2012-01-01

    Background and purpose A variety of risk factors have been hypothesized to contribute to the development of fracture-healing complications; however, population-based estimates of the strength of these risk factors are limited. In this case-control study, we evaluated patient-related risk factors for fracture-healing complications. Methods Using the United Kingdom General Practice Research Database, we identified patients with a fracture-healing complication (delayed union, nonunion, or maluni...

  11. Creating a sampling frame for population-based veteran research: Representativeness and overlap of VA and Department of Defense databases

    Donna L. Washington, MD, MPH; Su Sun, MPH; Mark Canning, BA

    2010-01-01

    Most veteran research is conducted in Department of Veterans Affairs (VA) healthcare settings, although most veterans obtain healthcare outside the VA. Our objective was to determine the adequacy and relative contributions of Veterans Health Administration (VHA), Veterans Benefits Administration (VBA), and Department of Defense (DOD) administrative databases for representing the U.S. veteran population, using as an example the creation of a sampling frame for the National Survey of Women Vete...

  12. Scientometric dimensions of nuclear science and technology research in India : a study based on INIS (1970-2002) database

    Kademani, B. S.; Vijai, Kumar; Anil, Sagar; Anil, Kumar

    2006-01-01

    This paper attempts to analyse quantitatively the growth and development of Nuclear Science and Technology research in India in terms of publication output as reflected in International Nuclear Information System (INIS) (1970-2002) database. During 1970-2002 a total of 55313 papers were published by the Indian Nuclear scientists to various domains : Physics (23033), Chemistry (16368),Life and Environmental Sciences (7203) Engineering and Technology ( 6960), Other Aspects of Nuclear and Non Nu...

  13. Historical land use databases: a new layer of information for geographical research

    Kramer, H.; Mücher, C.A.; Hazeu, G.W.

    2011-01-01

    In this paper we describe how historical land use information has been derived for the whole of Europe, using the World Atlas of Agriculture, scale 1: 2,500,000. This paper describes the process of converting the analog land-use maps to a digital European historical land-use database, the Historical

  14. D Digital Model Database Applied to Conservation and Research of Wooden Construction in China

    Zheng, Y.

    2013-07-01

    Protected by the Tai-Hang Mountains, Shanxi Province, located in north central China, is a highly prosperous, densely populated valley and considered to be one of the cradles of Chinese civilization. Its continuous habitation and rich culture have given rise to a large number of temple complexes and pavilions. Among these structures, 153 can be dated as early as from the Tang dynasty (618- 907C.E.) to the end of the Yuan dynasty (1279-1368C.E.) in Southern Shanxi area. The buildings are the best-preserved examples of wooden Chinese architecture in existence, exemplifying historic building technology and displaying highly intricate architectural decoration and detailing. They have survived war, earthquakes, and, in the last hundred years, neglect. In 2005, a decade-long conservation project was initiated by the State Administration of Cultural Heritage of China (SACH) to conserve and document these important buildings. The conservation process requires stabilization, conservation of important features, and, where necessary, partial dismantlement in order to replace unsound structural elements. Project team of CHCC have developed a practical recording system that created a record of all building components prior to and during the conservation process. After that we are trying to establish a comprehensive database which include all of the 153 earlier buildings, through which we can easily entering, browse, indexing information of the wooden construction, even deep into component details. The Database can help us to carry out comparative studies of these wooden structures, and, provide important support for the continued conservation of these heritage buildings. For some of the most important wooden structure, we have established three-dimensional models. Connected the Database with 3D Digital Model based on ArcGIS, we have developed 3D Digital Model Database for these cherish buildings. The 3D Digital Model Database helps us set up an integrate information inventory

  15. 动态WEB数据库应用探究%Application Research of dynamic WEB database

    乔立龙

    2015-01-01

    数据库技术现在已经相对成熟,并且结构比较严谨,不过这个灵活度还不够,如果可以实现把数据库和web相结合,那么必定能够在很大程度上扩大数据库的一个应用领域,这个相结合的方式其实也是现在数据库技术研究的一个热点。本课题总介绍的动态WEB数据库技术是采用这个中间件来完成的,这个的一个实现方法是:使用中间件吧这个Web服务器还有数据库服务器连在一个。由于中间件不当当可以使得前端用户能够访问后端异构数据库的这个数据源而达到一个中间件透明化的效果,同时还能够确保存取访问接口的一个开放性。%Database technology is already mature,and more rigorous structure,but this flexibility is not enough,if can realize the combination of database and web,then will be able to expand the database in a large extent of an applied field,the combination of in fact,is now the database technology a hot. This topic describes the dynamic web database technology is using the middleware to accomplish,this a realization method is that using middleware it the web server and database server connected to a.Due to the middleware Dangdang can make the front-end user to access heterogeneous backend database with the data source to a middleware transparency effect,but also can ensure the access interface of an open.

  16. Geoscientific (GEO) database of the Andra Meuse / Haute-Marne research center

    Document available in extended abstract form only. The GEO database (geo-scientific database of the Meuse/Haute-Marne Center) is a tool developed by Andra, with a view to group in a secured computer form all data related to the acquisition of in situ and laboratory measurements made on solid and fluid samples. This database has three main functions: - Acquisition and management of data and computer files related to geological, geomechanical, hydrogeological and geochemical measurements on solid and fluid samples and in situ measurements (logging, on sample measurements, geological logs, etc). - Available consultation by the staff on Andra's intranet network for selective viewing of data linked to a borehole and/or a sample and for making computations and graphs on sets of laboratory measurements related to a sample. - Physical management of fluid and solid samples stored in a 'core library' in order to localize a sample, follow-up its movement out of the 'core library' to an organization, and carry out regular inventories. The GEO database is a relational Oracle data base. It is installed on a data server which stores information and manages the users' transactions. The users can consult, download and exploit data from any computer connected to the Andra network or Internet. Management of the access rights is made through a login/ password. Four geo-scientific explanations are linked to the Geo database, they are: - The Geosciences portal: The Geosciences portal is a web Intranet application accessible from the ANDRA network. It does not require a particular installation from the client and is accessible through the Internet navigator. A SQL Server Express database manages the users and access rights to the application. This application is used for the acquisition of hydrogeological and geochemical data collected on the field and on fluid samples, as well as data related to scientific work carried out at surface level or in drifts

  17. A plant resource and experiment management system based on the Golm Plant Database as a basic tool for omics research

    Selbig Joachim

    2008-05-01

    names generated by the system and barcode labels facilitate identification and management of the material. Web pages are provided as user interfaces to facilitate maintaining the system in an environment with many desktop computers and a rapidly changing user community. Web based search tools are the basis for joint use of the material by all researchers of the institute. Conclusion The Golm Plant Database system, which is based on a relational database, collects the genetic and environmental information on plant material during its production or experimental use at the Max-Planck-Institute of Molecular Plant Physiology. It thus provides information according to the MIAME standard for the component 'Sample' in a highly standardised format. The Plant Database system thus facilitates collaborative work and allows efficient queries in data analysis for systems biology research.

  18. Development of a database for prompt γ-ray neutron activation analysis. Summary report of the first research coordination meeting

    This report summarizes the presentations, recommendations and conclusions of the First Research Co-ordination Meeting on Development of a Database for Prompt γ-ray Neutron Activation Analysis. Neutron-capture Prompt γ-ray Activation Analysis (PGAA) is a non-destructive radioanalytical method, capable of rapid or in-situ simultaneous multielement analysis of many elements of the Periodic Table, from hydrogen to uranium, in the same sample. Inaccuracy and incompleteness of the data available for use in PGAA are a significant handicap in the qualitative and quantitative analysis of capture-gamma spectra. The goal of this CRP is to replace the twenty-year-old data from a single laboratory with something fundamentally new: an evaluated database which includes a combination of evaluated nuclear physics data, physical theory, and recent measurements. The resulting database will be comparable in quality with that for radioactive decay. In addition, more accurate values of neutron capture cross-sections and γ-ray intensities that result from this database will improve the accuracy of radiation shielding calculations. (author)

  19. Oracle数据库应用中安全问题研究%Research Oracle Database Application Security Issues

    姚树春

    2014-01-01

    The Oracle database is the most direct way for enterprises to share resources, and its own security has also become the focus of one of the elements considered in today's enterprise. Although database systems bring people in dealing with the many convenient data problems, but also to the system brought a lot of security risks, in order to ensure reliable and secure database management system to ensure safety in the application of this paper, the Oracle database application security issues make research initiatives.%Oracle数据库的建立是企业实现资源共享的最直接途径,其自身的安全性也成为现今企业重点考虑的要素之一。尽管数据库系统带给了人们在处理数据问题上的诸多便利,但同时也给系统带来了诸多安全隐患,为保证数据库系统管理的安全可靠、确保在应用方面的安全性,本文就Oracle数据库应用中安全问题的举措做出研究。

  20. Establishment of database and network for research of stream generator and state of the art technology review

    A significant number of steam generator tubes are defective and are removed from service or repaired world widely. This wide spread damage has been caused by diverse degradation mechanisms, some of which are difficult to detect and predict. Regarding domestic nuclear power plants, also, the increase of number of operating nuclear power plants and operating periods may result in the increase of steam generator tube failure. So, it is important to carry out the integrity evaluation process to prevent the steam generator tube damage. There are two objectives of this research. The one is to make database for the research of steam generator at domestic research institution. It will increase the efficiency and capability of limited domestic research resources by sharing data and information through network organization. Also, it will enhance the current standard of integrity evaluation procedure that is considerably conservative but can be more reasonable. The second objective is to establish the standard integrity evaluation procedure for steam generator tube by reviewing state of the art technology. The research resources related to steam generator tubes are managed by the established web-based database system. The following topics are covered in this project: development of web-based network for research on steam generator tubes review of state of the art technology

  1. Establishment of database and network for research of stream generator and state of the art technology review

    Choi, Jae Bong; Hur, Nam Su; Moon, Seong In; Seo, Hyeong Won; Park, Bo Kyu; Park, Sung Ho; Kim, Hyung Geun [Sungkyunkwan Univ., Seoul (Korea, Republic of)

    2004-02-15

    A significant number of steam generator tubes are defective and are removed from service or repaired world widely. This wide spread damage has been caused by diverse degradation mechanisms, some of which are difficult to detect and predict. Regarding domestic nuclear power plants, also, the increase of number of operating nuclear power plants and operating periods may result in the increase of steam generator tube failure. So, it is important to carry out the integrity evaluation process to prevent the steam generator tube damage. There are two objectives of this research. The one is to make database for the research of steam generator at domestic research institution. It will increase the efficiency and capability of limited domestic research resources by sharing data and information through network organization. Also, it will enhance the current standard of integrity evaluation procedure that is considerably conservative but can be more reasonable. The second objective is to establish the standard integrity evaluation procedure for steam generator tube by reviewing state of the art technology. The research resources related to steam generator tubes are managed by the established web-based database system. The following topics are covered in this project: development of web-based network for research on steam generator tubes review of state of the art technology.

  2. Bioinformatics glossary based Database of Biological Databases: DBD

    Siva Kiran RR; Setty MVN; Hanumatha Rao G

    2009-01-01

    Database of Biological/Bioinformatics Databases (DBD) is a collection of 1669 databases and online resources collected from NAR Database Summary Papers (http://www.oxfordjournals.org/nar/database/a/) & Internet search engines. The database has been developed based on 437 keywords (Glossary) available in http://falcon.roswellpark.org/labweb/glossary.html. Keywords with their relevant databases are arranged in alphabetic order which enables quick accession of databases by researchers. Dat...

  3. Identification of Oxygenated Fatty Acid as a Side Chain of Lipo-Alkaloids in Aconitum carmichaelii by UHPLC-Q-TOF-MS and a Database

    Ying Liang

    2016-03-01

    Full Text Available Lipo-alkaloid is a kind of C19-norditerpenoid alkaloid usually found in Aconitum species. Structurally, they contain an aconitane skeleton and one or two fatty acid moieties of 3–25 carbon chains with 1–6 unsaturated degrees. Analysis of the lipo-alkaloids in roots of Aconitum carmichaelii resulted in the isolation of six known pure lipo-alkaloids (A1–A6 and a lipo-alkaloid mixture (A7. The mixture shared the same aconitane skeleton of 14-benzoylmesaconine, but their side chains were determined to be 9-hydroxy-octadecadienoic acid, 13-hydroxy-octadecadienoic acid and 10-hydroxy-octadecadienoic acid, respectively, by MS/MS analysis after alkaline hydrolysis. To our knowledge, this is the first time of the reporting of the oxygenated fatty acids as the side chains in naturally-occurring lipo-alkaloids. In order to identify more lipo-alkaloids, a compound database was established based on various combinations between the aconitane skeleton and the fatty acid chain, and then, the identification of lipo-alkaloids was conducted using the database, UHPLC-Q-TOF-MS and MS/MS. Finally, 148 lipo-alkaloids were identified from A. carmichaelii after intensive MS/MS analysis, including 93 potential new compounds and 38 compounds with oxygenated fatty acid moieties.

  4. Proyecto AVIS: a Spanish open access bird database available for research

    Sara Varela; Eduardo Casabella; José Antonio Palomar; Juan Antonio Arce; José Carlos González; Rafael Barrientos

    2014-01-01

    Proyecto AVIS1 is an open access citizen science database that stores information collected by amateur ornithologists about bird occurrences and abundance in Spain. Proyecto AVIS was launched in 2005 and today stores data from 415 species (ca. 90% of bird species in Spain); it covers 30% of the Spanish territory, including the Canary Islands in the Atlantic Ocean and the Balearic Islands in the Mediterranean Sea. Here, we acknowledge the work of all the volunteers that have gathered bird reco...

  5. The Human Studies Database Project: Federating Human Studies Design Data Using the Ontology of Clinical Research

    Sim, Ida; Carini, Simona; Tu, Samson; Wynden, Rob; Pollock, Brad H.; Mollah, Shamim A.; Gabriel, Davera; Hagler, Herbert K.; Scheuermann, Richard H.; Lehmann, Harold P.; Wittkowski, Knut M.; Nahm, Meredith; Bakken, Suzanne

    2010-01-01

    Human studies, encompassing interventional and observational studies, are the most important source of evidence for advancing our understanding of health, disease, and treatment options. To promote discovery, the design and results of these studies should be made machine-readable for large-scale data mining, synthesis, and re-analysis. The Human Studies Database Project aims to define and implement an informatics infrastructure for institutions to share the design of their human studies. We h...

  6. PGSB PlantsDB: updates to the database framework for comparative plant genome research

    Spannagl, Manuel; Nussbaumer, Thomas; Bader, Kai C.; Martis, Mihaela M.; Seidel, Michael; Kugler, Karl G.; Gundlach, Heidrun; Mayer, Klaus F. X

    2015-01-01

    PGSB (Plant Genome and Systems Biology: formerly MIPS) PlantsDB (http://pgsb.helmholtz-muenchen.de/plant/index.jsp) is a database framework for the comparative analysis and visualization of plant genome data. The resource has been updated with new data sets and types as well as specialized tools and interfaces to address user demands for intuitive access to complex plant genome data. In its latest incarnation, we have re-worked both the layout and navigation structure and implemented new keyw...

  7. PGSB PlantsDB: updates to the database framework for comparative plant genome research

    Spannagl, Manuel; Nussbaumer, Thomas; Bader, Kai C.; Martis, Mihaela-Maria; Seidel, Michael; Kugler, Karl G; Gundlach, Heidrun; Mayer, Klaus F. X.

    2016-01-01

    PGSB (Plant Genome and Systems Biology: formerly MIPS) PlantsDB (http://pgsb.helmholtz-muenchen.de/plant/index.jsp) is a database framework for the comparative analysis and visualization of plant genome data. The resource has been updated with new data sets and types as well as specialized tools and interfaces to address user demands for intuitive access to complex plant genome data. In its latest incarnation, we have re-worked both the layout and navigation structure and implemented new keyw...

  8. Oracle Database Security Research%Oracle数据库安全性分析研究

    胡歆

    2012-01-01

    随着计算机网络的发展,数据的共享日益加强,数据的安全保密越来越重要。为了响应数据安全需求,Oracle在其数据库产品中实现了强大的安全特性。文章从数据库用户安全、权限设置、数据限制等几个方面对Oracle数据库的安全性能进行分析研究。%With the development of computer network,data sharing is strengthened increasingly,data security is becoming more and more important.In response to the data security requirements,Oracle in its database product to achieve a strong security features.This article from the database user permissions settings,security,data on several aspects such as the Oracle database security performance analysis.

  9. Data Mining in Distributed Database of the First Egyptian Thermal Research Reactor (ETRR-1)

    Distributed database (DDB)technology application systems are growing up to cover many fields an domains, and at different levels. the aim of this paper is to shade some lights on applying the new technology of distributed database on the ETRR-1 operation data logged by the data acquisition system (DACQUS)and one can extract a useful knowledge. data mining with scientific methods and specialize tools is used to support the extraction of useful knowledge from the rapidly growing volumes of data . there are many shapes and forms for data mining methods. predictive methods furnish models capable of anticipating the future behavior of quantitative or qualitative database variables. when the relationship between the dependent an independent variables is nearly liner, linear regression method is the appropriate data mining strategy. so, multiple linear regression models have been applied to a set of data samples of the ETRR-1 operation data, using least square method. the results show an accurate analysis of the multiple linear regression models as applied to the ETRR-1 operation data

  10. Establishing the user requirements for the research reactor decommissioning database system

    In generally, so much information and data will be raised during the decommissioning activities. It is need a systematical electric system for the management of that. A database system for the decommissioning information and data management from the KRR-1 and 2 decommissioning project is developing now. All information and data will be put into this database system and retrieval also. For the developing the DB system, the basic concept, user requirements were established the then set up the system for categorizing the information and data. The entities of tables for input the data was raised and categorized and then converted the code. The ERD (Entity Relation Diagram) was also set up to show their relation. In need of the developing the user interface system for retrieval the data, is should be studied the analyzing on the relation between the input and output the data. Through this study, as results, the items of output tables are established and categorized according to the requirement of the user interface system for the decommissioning information and data. These tables will be used for designing the prototype and be set up by several feeds back for establishing the decommissioning database system