Swinburn Boyd; Vos Theo; Magnus Anne; Markwick Alison; Moodie Marj; Carter Rob; Haby Michele M
Abstract Background The aim of the ACE-Obesity study was to determine the economic credentials of interventions which aim to prevent unhealthy weight gain in children and adolescents. We have reported elsewhere on the modelled effectiveness of 13 obesity prevention interventions in children. In this paper, we report on the cost results and associated methods together with the innovative approach to priority setting that underpins the ACE-Obesity study. Methods The Assessing Cost Effectiveness...
Full Text Available Abstract Background The aim of the ACE-Obesity study was to determine the economic credentials of interventions which aim to prevent unhealthy weight gain in children and adolescents. We have reported elsewhere on the modelled effectiveness of 13 obesity prevention interventions in children. In this paper, we report on the cost results and associated methods together with the innovative approach to priority setting that underpins the ACE-Obesity study. Methods The Assessing Cost Effectiveness (ACE approach combines technical rigour with 'due process' to facilitate evidence-based policy analysis. Technical rigour was achieved through use of standardised evaluation methods, a research team that assembles best available evidence and extensive uncertainty analysis. Cost estimates were based on pathway analysis, with resource usage estimated for the interventions and their 'current practice' comparator, as well as associated cost offsets. Due process was achieved through involvement of stakeholders, consensus decisions informed by briefing papers and 2nd stage filter analysis that captures broader factors that influence policy judgements in addition to cost-effectiveness results. The 2nd stage filters agreed by stakeholders were 'equity', 'strength of the evidence', 'feasibility of implementation', 'acceptability to stakeholders', 'sustainability' and 'potential for side-effects'. Results The intervention costs varied considerably, both in absolute terms (from cost saving [6 interventions] to in excess of AUD50m per annum and when expressed as a 'cost per child' estimate (from Conclusion The use of consistent methods enables valid comparison of potential intervention costs and cost-offsets for each of the interventions. ACE-Obesity informs policy-makers about cost-effectiveness, health impact, affordability and 2nd stage filters for important options for preventing unhealthy weight gain in children. In related articles cost-effectiveness results and
This volume consists of seven appendices related to ACES, the first three of which are concerned with computer programs. The appendices are entitled: (A) ACESIM: Residential Program Listing; (B) Typical Inputs and Outputs of ACESIM; (C) CACESS: Commercial Building Program Listing; (D) Typical Weather-Year Selection Requirements; (E) Building Characteristics; (F) List of Major Variables Used in the Computer Programs; and (G) Bibliography. 79 references.
Economics education is circumscribe a multiplicative feedback through expansion, diversification, intensive interaction between the economy and education, as being in an economic perspective on education, along with sociological, psychological, technological, religious, family, public, etc. pespective, in other words, an application of economic theories, paradigms and approaches to economic education act, act deeply human, spiritual nature. In practice perspective, the economy has education a...
This chapter explores the potential advantages and disadvantages of Agent-based Computational Economics (ACE) for the study of economic systems. General points are concretely illustrated using an ACE model of a two-sector decentralized market economy. Six issues are highlighted: Constructive understanding of production, pricing, and trade processes; the essential primacy of survival; strategic rivalry and market power; behavioral uncertainty and learning; the role of conventions and organizat...
Full Text Available Neo-fermented buckwheat sprouts (neo-FBS contain angiotensin-converting enzyme (ACE inhibitors and vasodilators with blood pressure-lowering (BPL properties in spontaneously hypertensive rats (SHRs. In this study, we investigated antihypertensive mechanisms of six BPL peptides isolated from neo-FBS (FBPs by a vasorelaxation assay and conventional in vitro, in vivo, and a new ex vivo ACE inhibitory assays. Some FBPs demonstrated moderate endothelium-dependent vasorelaxation in SHR thoracic aorta and all FBPs mildly inhibited ACE in vitro. Orally administered FBPs strongly inhibited ACE in SHR tissues. To investigate detailed ACE-inhibitory mechanism of FBPs in living body tissues, we performed the ex vivo assay by using endothelium-denuded thoracic aorta rings isolated from SHRs, which demonstrated that FBPs at low concentration effectively inhibited ACE in thoracic aorta tissue and suppressed angiotensin II-mediated vasoconstriction directly associated with BPL. These results indicate that the main BPL mechanism of FBP was ACE inhibition in living body tissues, suggesting that high FBP's bioavailability including absorption, tissue affinity, and tissue accumulation was responsible for the superior ACE inhibition in vivo. We propose that our ex vivo assay is an efficient and reliable method for evaluating ACE-inhibitory mechanism responsible for BPL activity in vivo.
Bergh, van den, H.
This provides a short overview of the main themes of ecological economics (EE). It isargued that EE provides a platform that fosters multidisciplinary environmental research bybringing together the core contributing disciplines economics and ecology. In addition, EE isregarded as a pluralistic approach to environmental research that can be set opposite to, and hasindeed developed as a response to, traditional environmental and resource economics. Acomparison of the two fields is presented to ...
Karl A Hassan
Full Text Available The era of antibiotics as a cure-all for bacterial infections appears to be coming to an end. The emergence of multidrug resistance in many hospital-associated pathogens has resulted in superbugs that are effectively untreatable. Multidrug efflux pumps are well known mediators of bacterial drug resistance. Genome sequencing efforts have highlighted an abundance of putative efflux pump genes in bacteria. However, it is not clear how many of these pumps play a role in antimicrobial resistance. Several studies have demonstrated that efflux pump genes that participate in drug resistance are typically under tight regulatory control and expressed only in response to their substrates. Consequently, changes in gene expression following antimicrobial shock treatments may be used to identify efflux pumps that mediate antimicrobial resistance, informing targeted functional analyses of these proteins. Using this approach we have characterised novel efflux pumps in both Gram-negative and Gram-positive bacteria. Notably, we recently applied this strategy to characterise the AceI efflux pump from Acinetobacter. AceI is a prototype for a new family of multidrug efflux proteins that is conserved across many proteobacterial lineages. Different efflux pumps in this family have been shown to confer resistance to biocides including chlorhexidine, dequalinium, benzalkonium, proflavine and/or acriflavine. The discovery of this novel family of multidrug efflux proteins raises the possibility that additional undiscovered intrinsic resistance proteins may be encoded in the core genomes of pathogenic bacteria.
Martins, Nuno O.
Copyright © 2011 Elsevier B.V. All rights reserved. The relationship between sustainability economics and the capability approach has recently been explored. Here I shall discuss this relationship, and argue that a study of the ontology underlying the capability approach can help us to see more clearly the interconnections between sustainability economics and the capability approach. In particular, the interpretations of the capability approach as an ontological exercise, which have recent...
Falch, Morten; Tadayoni, Reza
While telecom markets have been liberalized, the institutional framework for spectrum management has largely remained unchanged. In particular, the process of allocation of the spectrum to different applications is still based on technical rather than economic criteria. This paper contrasts...... economic and technical approaches to frequency management, with an examination of spectrum management challenges and the current regulatory framework as the starting point. The benefits and limitations of the free market approach are discussed, and an economic evaluation of the Danish spectrum is used to...
Global environmental problems raise a host of major policy questions. They are all scientifically complex and controversial, and no scientific consensus is likely to emerge until irreversible decisions have been made. The costs and benefits of these changes transcend national boundaries, and nations, which cannot appropriate the global costs and benefits of such changes, are unlikely to be able or willing to make efficient decisions on how to combat these global externalities. In addition, these concerns sometimes have impacts over hundreds of years and thereby strain political decision making, which often functions effectively only when the crisis is at hand. This chapter considers some of the economic issues involved in deciding how to react to the threat of global warming. The author first reviews the theory and evidence on the greenhouse effect. He then presents evidence on the impacts of greenhouse warming, the costs of stabilizing climate, and the kinds of adaptations that might be available. In the final section, he reviews the policy initiatives that nations might follow in the near term
Full Text Available The paper aims to assess how economic benchmarking is being used by airports as a means of performance measurement and comparison of major international airports in the world. The study focuses on current benchmarking practices and methods by taking into account different factors according to which it is efficient to benchmark airports performance. As methods are considered mainly data envelopment analysis and stochastic frontier analysis. Apart from them other approaches are discussed by airports to provide economic benchmarking. The main objective of this article is to evaluate the efficiency of the airports and answer some undetermined questions involving economic benchmarking of the airports.
The paper aims to assess how economic benchmarking is being used by airports as a means of performance measurement and comparison of major international airports in the world. The study focuses on current benchmarking practices and methods by taking into account different factors according to which it is efficient to benchmark airports performance. As methods are considered mainly data envelopment analysis and stochastic frontier analysis. Apart from them other approaches are discussed by air...
Vleeming W; van Amsterdam JGC; de Wildt DJ; Stricker B; TOX
Dit rapport beschrijft de risico's die verbonden zijn aan het gebruik van angiotensine converting enzym (ACE) remmers. Hierbij staat de bijwerking angio-oedeem centraal. De benodigde literatuur is verzameld aan de hand van een zoekaktie middels MEDLINE. ACE-remmers zijn in gebruik ter behand
This publication presents options raised through various forums for marketing adult and community education (ACE) in Victoria, Australia, and suggested strategies. After an introduction (chapter 1), chapters 2 and 3 provide a broad view of the current situation for marketing ACE. Chapter 2 discusses general issues in the current position--ACE…
Full Text Available Article deals with category of time from economic point of view. Dependence of economic systems from economic time is analyzed. Based on analysis of economic time definition its features are improved.
Environmental economics postulates the assumption of homo economicus and presumes that externality occurs as a result of the rational economic activities of economic agents. This paper examines this assumption using an experimental economic approach in the context of regime shift, which has been receiving increasing attention. We observe that when externality does not exist, economic agents (subjects of experimemt) act economically rationally, but when externality exists, economic agents avoi...
Yan, T.; Shih, J.; Sanchirico, J. N.
Although groundwater accounts for about 20% of the water consumption in the US, recent urban development, land use changes and agricultural activities in many regions (for example, Chesapeake Bay and eastern shore of Maryland) have resulted in deleterious impacts on groundwater quality. These impacts have dramatically increased potential human health and ecological system risks. One example is nitrogen pollution delivered to local waterways from septic systems via groundwater. Conventional approaches for nitrogen removal, such as pumping and treatment (nitrification-denitrification) process, tend to be expensive. On the other hand, economic incentive approaches (such as marketable permits) have the potential to increase the efficiency of environmental policy by reducing compliance costs for regulated entities and individuals and/or achieving otherwise uneconomical pollution reduction. The success of the sulfur dioxide trading market has led to the creation of trading markets for other pollutants, especially at the regional, state, and smaller (e.g. watershed) scales. In this paper, we develop an integrated framework, which includes a groundwater flow and transport model, and a conceptual management model. We apply this framework to a synthetic set up which includes one farm and two development areas in order to investigate the potential of using economic incentive approaches for groundwater quality management. The policy analysis is carried out by setting up the objective of the modeling framework to minimize the total cost of achieving groundwater quality goals at specific observation point using either a transferable development right (TDR) system between development areas and/or using a tax for fertilizer usage in the farm area. The TDR system consists of a planning agency delineating a region into restricted-use (e.g., agriculture, open space) and high intensity zones (e.g., residential, commercial uses). The agency then endows landowners in the restricted area
The Antiproton Cell Experiment (ACE) as shown by Michael Holzscheiter (spokesperson), Niels Bassler (co-spokesperson) and Helge Knudsen. ACE is located on the Antiproton Decelerator (AD) at CERN. An antiproton annihilates a proton in the nucleus of a cancer cell, producing a pair of gamma rays, destroying the entire cell and some surrounding cells. Many fewer antiprotons are required in this treatment than in the equivalent proton hadron therapy, so there is less risk of healthy tissue damage.
Turgut, Mehmet Burak
This paper studies the spatial economic activity in Turkey and estimates the correlation between wages and consumer demand across NUTS1 regions of Turkey. First, I estimate simple market potential function to test whether closeness to larger markets has impact on wages. Second, I estimate Krugman (1993) economic geography model to see the agglomeration forces in Turkey. The results suggest that wages are higher in the regions close to larger markets and low trade costs and high share of expen...
Desplaces, David E.; Wergeles, Fred; McGuigan, Patrick
This article outlines the implementation of a service-learning approach in an entrepreneurship programme using an "economic gardening" strategy. Economic Gardening through Service-Learning (EGS-L) is an approach to economic development that helps local businesses and students grow through a facilitated learning process. Learning is made possible…
Purpose: The purpose of this paper is to review the focus and practice of Adult and Community Education (ACE) as well as its conceptualization and delivery and to suggest parameters for an approach based on excellence, a balanced scorecard and performance to meet community needs. Design/methodology/approach: The review examines key aspects of the…
Clive L Spash; Mauricio G. Villena
A neglected aspect of ecological economics is the link to the social context. The socio-economic perspective extends standard economic analysis into concerns for distribution, ethics and the power of institutions which form and implement policy. We explore how an institutional perspective on ecological economics might operate and provide a distinct methodology. In order to understand the institutional approach and how it differs from the standard economic methodology a historical overview...
Full Text Available Object oriented development languages and event driven programming, distributed or centralized data processing with thick or rich clients are used at present in information systems (IS development. Using of existing methodologies and methods In IS designing does not always mean reaching of needed project solution quality. In some cases it is more effective to use combination of structured and object oriented tools or new methodology, which is built according the newest information technologies. One of such methodologies is Advanced Customer Oriented Development of Software (ACES, which is oriented on IS of economic organization development and application of the newest information technologies. ACES was established by the authors at Faculty of Economic Informatics of University of Economics in Bratislava.
Ciani Scarnicci, Manuela
Amartya Sen (1933-) is one of the greatest scholars who studied the relationship between ethics and economics and was held the Nobel Economics Prize thanks to this. At the awarding of the Nobel prize, while talking about his studies, the motive was: “...has been highly instrumental in restoring an ethical dimension to economics and related disciplines”. Precisely the theories of this binomial taken from the work of A. Sen “Economics and Ethics” are the basis of this work. Thanks to A. Se...
Bergh, van den, E.; Gowdy, J.
Recent advances in evolutionary theory have important implications for environmental economics. A short overview is offered of evolutionarythinking in economics. Subsequently, major concepts and approaches inevolutionary biology and evolutionary economics are presented andcompared. Attention is devoted, among others, to Darwinian selection,punctuated equilibrium, sorting mechanisms, Lamarckian evolution,coevolution and self-organization. Basic features of evolution, such assustained change, i...
Meyer, William V.; Sicker, Ron; Brown, Dan; Eustace, John
Increment 45 - 46 Science Symposium presentation of Advanced Colloids Experiment (ACE-T1) to RPO. The purpose of this event is for Principal Investigators to present their science objectives, testing approach, and measurement methods to agency scientists, managers, and other investigators.
McHale, John; Rogers, Keith
There is growing international interest in a Canadian-style points system for selecting economic immigrants. Although existing points systems have been influenced by the human capital literature, the findings have traditionally been incorporated in an ad hoc way. This paper explores a formal method for designing a points system based on a human capital earnings regression for predicting immigrant economic success. The method is implemented for Canada using the IMDB, a remarkable longitudinal ...
Posner, Richard A
With the rise of the law and economics movement, the focus of economic analysis of intellectual property has begun to shift to more concrete and manageable issues concerning the structure and texture of the complicated pattern of common law and statutory doctrines, legal institutions and business practices relating to intellectual property. Among the issues discussed in this paper are the length of protection for intellectual property, the rules that allow considerable copying of intellectual...
Nowadays, more than ever, economic relations between states are the ones that define the general character of the relations between them and establish economic security as a concept which cannot be neglected anymore. Globalization, the process that shapes the international environment, undermines the old definition of economic security and forces its redefinition. The article aims to identify and analyse the effects of globalization on economic security and the new approaches it takes in this...
Development economists are increasingly concerned about the correct approach to economic analysis of projects. By looking for a compromise between theory (which identifies ideals) and practice (which deals within the bounds of time and resource constraints), Lovei focuses on potential guidelines for economic appraisals of water supply projects. He summarizes theory and the current World Bank guidelines on the economic analysis of water supply projects; reviews the method of economic analysis ...
Full Text Available Nowadays, more than ever, economic relations between states are the ones that define the general character of the relations between them and establish economic security as a concept which cannot be neglected anymore. Globalization, the process that shapes the international environment, undermines the old definition of economic security and forces its redefinition. The article aims to identify and analyse the effects of globalization on economic security and the new approaches it takes in this context.
Pradeep Kumar Arora* and Ashish Chauhan
Full Text Available Hypertension is a chronic increase in blood pressure, characterized as primary and secondary hypertension. The disorder is associated with various risk factors like obesity, diabetes, age, lack of exercise etc. Hypertension is being treated since ancient times by Ayurvedic, Chinese and Unani medicine. Now various allopathic drugs are available which include diuretics, calcium channel blockers, α-blockers, β-blockers, vasodilators, central sympatholytics and ACE-inhibitors. Non-pharmacological treatments include weight reduction, dietary sodium reduction, increased potassium intake and reduction in alcohol consumption. ACE-inhibitors are widely used in the treatment of hypertension by inhibiting the angiotensin converting enzyme responsible for the conversion of angiotensin I to angiotensin II (responsible for vasoconstriction. Various structure activity relationship studies led to the synthesis of ACE-inhibitors, some are under clinical development. This comprehensive review gives various guidelines on classification of hypertension, hypertension therapy including ancient, pharmacological, non-pharmacological therapies, pharmacoeconomics, historical perspectives of ACE, renin, renin angiotensin system (circulating vs local RAS, mechanism of ACE inhibitors, and development of ACE inhibitors. Review also emphasizes on the recent advancements on ACE inhibitors including drugs in clinical trials, computational studies on ACE-inhibitors, peptidomimetics, dual, natural, multi-functional ACE inhibitors, and conformational requirements for ACE-inhibitors.
Dziubinski, Matt P.; Grassi, Stefano
This paper shows the potential of heterogeneous computing in solving dynamic equilibrium models in economics. We illustrate the power and simplicity of the C++ Accelerated Massive Parallelism recently introduced by Microsoft. Starting from the same exercise as Aldrich et al. (2011) we document a...
Dziubinski, Matt P.; Grassi, Stefano
This paper shows the potential of heterogeneous computing in solving dynamic equilibrium models in economics. We illustrate the power and simplicity of the C++ Accelerated Massive Parallelism recently introduced by Microsoft. Starting from the same exercise as Aldrich et al. (2011) we document a speed gain together with a simplified programming style that naturally enables parallelization.
Nuno Carlos LEITÃO
Full Text Available The relationship between financial development and economic growth has been studied long time in economics (Adam Smith and Schumpeter. Structural reforms and the integration of financial markets have been attracting the interest of the academic community. This manuscript examines the link between financial development and economic growth. The European Union Countries (EU-27, and BRIC (Brazil, Russia, India and China were examined, between 1980 and 2006. Using a static and dynamic panel data approach, the results demonstrate that the financial development contribute to economic growth. Our study also consider productivity and trade, these proxies confirm the positive effect on economic growth.
As pointed out in the OECD BEMUSE Program, when a high computation time is taken to obtain the relevant output values of a complex physical model (or code), the number of statistical samples that must be evaluated through it is a critical factor for the sampling-based uncertainty analysis. Two alternative methods have been utilized to avoid the problem associated with the size of these statistical samples: one is based on Wilks' formula, which is based on simple random sampling, and the other is based on the conventional nonlinear regression approach. While both approaches provide a useful means for drawing conclusions on the resultant uncertainty with a limited number of code runs, there are also some unique corresponding limitations. For example, a conclusion based on the Wilks' formula can be highly affected by the sampled values themselves, while the conventional regression approach requires an a priori estimate on the functional forms of a regression model. The main objective of this paper is to assess the feasibility of the ACE-RSM approach as a complementary method to the Wilks' formula and the conventional regression-based uncertainty analysis. This feasibility was assessed through a practical application of the ACE-RSM approach to the LOFT L2-5 LBLOCA PCT uncertainty analysis, which was implemented as a part of the OECD BEMUSE Phase III program
Meisam Karami; Shaghayegh Malekifar; Muhammad Siddique; Saif-Ur-Rehman Khan
Organizational change in Transitional economies is influenced by multiple political, historical and economic factors not present in established market economies. This study proposes an organizational economics approach to organizational change in emerging economies. Based on transaction cost economics and resource based view, the cost of change is proposed as a mediator of change and perceived commitment to transition is proposed as antecedents of cost of change for organizations in emerging ...
As a result of this research, the methodical approaches to comprehensive economic assessment of water resources are worked out. In particular, it is offered to conduct the comprehensive economic assessment in three stages. In the first stage, the economic assessment of water resources as the basis of human life is carried out. The result of this assessment is the monetary value of social and environmental significance of water resource of water body for human and the environment. The main met...
Since the 1960s, the influence of economic thought on education has been steadily increasing. Taking Jean-Jacques Rousseau's educational thought as a point of departure, Tal Gilead critically inquires into the philosophical foundations of what can be termed the economic approach to education. Gilead's focus in this essay is on happiness and the…
Full Text Available In article features of an economic approach are considered when developing the anti-corruption measures directed on restriction of possibilities of any discretion and excessive intervention of civil servants in economic activity, including through differentiation of functions and specification of competences. The special urgency of researches of a problem of corruption as special social phenomenon is noted.
Full Text Available The author substantiated necessity of detailed classification of economic risks, formulated principles, which should be considered in a process ofdevelopment of classifications. The author described characteristics, which may be used for creation of a classification of economic risks. Classificationsdeveloped by modern scientists are proposed. The author offers to reduce characterization of a risk to such positions as uncertainty,danger, losses, and probability. Construction of a detailed classification of risks enable to most thoroughly attack the problem of appearance offactors that contribute a risk and to research risks as a whole. Thus, further researches in this branch continue to be actual and necessary, especiallyfor a practical activity. Basing on a classification, each type of a risk can be thoroughly analyzed, modeled, separated into elements. Theseprocesses enable to decrease uncertainty of a situation, making an appropriate decision. The classifications of risks considered in the article enableto determine a position of each type of risks in their general system and also effectively use particular techniques and methods of minimizationand management of risks.
Averch, Harvey A.
This article reviews the principal methods economists and cost benefit analysts use in evaluating research. Two common approaches are surplus measures (combinations of consumer and producer surpluses) and productivity measures. Technical difficulties and political and organizational constraints are discussed for these measures. (SLD)
Ion Gh. Rosca
Full Text Available Human society steps, with or without its willing, towards knowledge era which rises new exigencies for education and research. Universities are influenced and, in the same time, influence the new society. They define new duties, visions and aims according to the European common space organizing. New arguments appear as national priority, changes within concepts approaches are produced, universities adapt to new structures, integrate within education’s global market, ensuring a high level ofthe research and training services.
Ion Gh. Rosca
Full Text Available Human society steps, with or without its willing, towards knowledge era which rises new exigencies for education and research. Universities are influenced and, in the same time, influence the new society. They define new duties, visions and aims according to the European common space organizing. New arguments appear as national priority, changes within concepts approaches are produced, universities adapt to new structures, integrate within education’s global market, ensuring a high level of the research and training services.
This book takes the non-economist by the hand in a step-by-step economic approach of environmental issues and how to handle them. Two chapters provide an introduction to the concepts of the economy, chapter six in decision theory. In the first chapter, the economist discovers a broader vision by testing the economic approach to insights from other disciplines. Chapter 4 explains how economic reasoning can contribute tot environmental protection in practice. The consideration of the costs and benefits of environmental protection indicates objectives that must be pursued for the community. The conflict between private and public interest forces policy makers to get and maintain the numerous polluters focused on environmental protection. Suitable instruments are discussed in chapter five, including criteria for choice and an in-depth study of the economic instruments levies and tradable emission permits. The EU Emission trading Scheme is used as reference. [mk
Atkinson, Robert D.; Hackler, Darrene
In climate change, as in all policy issues, economic philosophy has a significant influence on how people view both the problems and the solutions. For the first time, ITIF surveys four dominant schools of economic thought and analyzes how adherents approach policy options for climate change and energy policy. With climate change and major energy legislation stalled, maybe it is time to put aside fixed philosophical notions and take a practical look on ways to address climate change in an eco...
Smith, Richard Gavin; Berry, Philippa A M
The new ACE2 (Altimeter Corrected Elevations 2) Global Digital Elevation Model (GDEM) which has recently been released aims to provide the most accurate GDEM to date. ACE2 was created by synergistically merging the SRTM and altimetry datasets. The comprehensive comparison carried out between the two datasets yielded a myriad of information, with the areas of disagreement providing as much valuable information as the areas of agreement. Analysis of the comparison dataset revealed that certain topographic features displayed consistent differences between the two datasets. The largest differences globally are present over the rainforests, particularly the two largest, around the Amazon and the Congo. The differences range between 10 m and 40 m; these differences can be attributed to the height of the rainforest canopy, as the SRTM returned height values from somewhere within the uppermost reaches of the vegetation whereas the altimeter was able to penetrate through and return true ground heights. The second major class of terrain feature to demonstrate coherent differences are desert regions; here, different deserts present different characteristics. The final area of interest is that of Wetlands; these are areas of special significance because even a slight misrepresentation of the heights can have wide ranging effects in modelling wetland areas. These examples illustrate the valuable additional information content gleaned from the synergistic global combination of the two datasets. PMID:21509388
Beginning RPG Maker VX Ace takes you through the process of using the RPG Maker VX Ace game development engine to create your very own role playing game. The book has been designed with the complete beginner in mind who has little to no experience with the engine. Tutorials and exercises will take you from installing the software to putting the final touches upon your first project. Game design can be quite a daunting challenge, as it generally involves a large amount of programming know-how on top of having to plan everything out that makes a good game what it is. RPG Maker VX Ace
Power Economic Dispatch (ED) is vital and essential daily optimization procedure in the system operation. Present day large power generating units with multi-valves steam turbines exhibit a large variation in the input-output characteristic functions, thus non-convexity appears in the characteristic curves. Various mathematical and optimization techniques have been developed, applied to solve economic dispatch (ED) problem. Most of these are calculus-based optimization algorithms that are based on successive linearization and use the first and second order differentiations of objective function and its constraint equations as the search direction. They usually require heat input, power output characteristics of generators to be of monotonically increasing nature or of piecewise linearity. These simplifying assumptions result in an inaccurate dispatch. Genetic algorithms have used to solve the economic dispatch problem independently and in conjunction with other AI tools and mathematical programming approaches. Genetic algorithms have inherent ability to reach the global minimum region of search space in a short time, but then take longer time to converge the solution. GA based hybrid approaches get around this problem and produce encouraging results. This paper presents brief survey on hybrid approaches for economic dispatch, an architecture of extensible computational framework as common environment for conventional, genetic algorithm and hybrid approaches based solution for power economic dispatch, the implementation of three algorithms in the developed framework. The framework tested on standard test systems for its performance evaluation. (authors)
This paper discusses the need for changing priorities in plant life management. Following a brief review of the major world-wide trends which are affecting plant life management, the fundamental nature of the plant life management process itself is considered. It is suggested that a consistent approach to the management of economic and safety risk can provide a mechanism for continuous improvement of the process. One such approach, Techno-Economic Ageing and Maintenance Management - TEAMM, is described. The tool required for this process are discussed and examples given of its application to ageing plant and evaluation of life extension. 2 figs
National Aeronautics and Space Administration — The proposed innovation is a static, cathode-fed, 2000 psi, balanced-pressure Advanced Cathode Electrolyzer (ACE) based on PEM electrolysis technology. It...
An Integrated Approach to Economical, Reliable, Safe Nuclear Power Production is the latest evolution of a concept which originated with the Defense-in-Depth philosophy of the nuclear industry. As Defense-in-Depth provided a framework for viewing physical barriers and equipment redundancy, the Integrated Approach gives a framework for viewing nuclear power production in terms of functions and institutions. In the Integrated Approach, four plant Goals are defined (Normal Operation, Core and Plant Protection, Containment Integrity and Emergency Preparedness) with the attendant Functional and Institutional Classifications that support them. The Integrated Approach provides a systematic perspective that combines the economic objective of reliable power production with the safety objective of consistent, controlled plant operation
Full Text Available Construction of short-length LDPC codes with good, both waterfall and error-floor, behavior is still an attractive research problem. Recently proposed construction algorithms in this field are based on remarkably simple ideas, but yet, their effectiveness can still be questioned. In this paper we investigate a novel measure of goodness of a given LDPC code namely its ACE spectrum, based on a previously introduced ACE metrics associated with each cycle in LDPC code graph.
aus dem Moore, Nils
We contribute to the empirical literature on the debt bias of corporate income taxation through a micro-econometric evaluation of the so-called ACE corporate tax reform in Belgium based on firm-level accounting data. We interpret the tax reform that came into effect in January 2006 as an economic quasi experiment. We identify its causal impact on the leverage ratio of Belgian corporations by means of a difference-in-differences (DiD) approach, using corporations from the UK as comparison grou...
Fernández, Francisco J.; Blanco, Maria
The economic effects of climate change on agriculture have been widely assessed in the last two decades. Many of these assessments are based on the integration of biophysical and agro-economic models, allowing to understand the physical and socio-economic responses of the agricultural sector to future climate change scenarios. The evolution of the bio-economic approach has gone through different stages. This review analyses its evolution: firstly, framing the bio-economic approach into the co...
The article formed the complex process of economic assessment of forest resources and given it's definition. A new approach to determining costs for locking the main types of forest. Allocated forestry (in Keywords: forest) and forest harvesting (in forest exploitation) rents.
WANG Xiao-yan; CAO Li-ping
This paper mainly discusses the feasibility to establish economic policy systems for control and management of agricultural nonpoint source pollution in China. The current situation of serious agricultural nonpoint source pollution in China is described firstly. Based on the environmental policy and economics theories, the system of economic policies for control and management of agricultural nonpoint source pollution is designed in this paper. This system includes the policy objective, the designing principle and the methods. The key issues include pollution charge,inputs tax for restriction, subsides for induction and incentive, effluent trading for least cost reduction. The emphases are optimized on inputs tax and agricultural chemical tax permit under complete information, as well as sub-optimized inputs tax under incomplete information, subsides for farm due to positive and negative externality. The functions and suitability of the policies are also analyzed in the paper. According to the field experiment results and other relating economic data in watershed of the Chaohe River, Beijing, some economic approaches to reducing agricultural nonpoint source pollution are proposed. The main idea is to encourage and support the farmers to improve their farming way,and to implement the policy of castigating charge simultaneously. The feasibility of the policies are analyzed with consideration of economy, technology and institution. It is concluded that the economic policies are necessary and feasible.
Recently previous works have shown that multilateral nuclear fuel cycle approach has benefits not only of non-proliferation but also of cost effectiveness. This is because for most facilities in nuclear fuel cycle, there exist economies of scale, which has a significant impact on the costs of nuclear fuel cycle. Therefore, the evaluation of economic rationality is required as one of the evaluation factors for the multilateral nuclear fuel cycle approach. In this study, we consider some options with respect to multilateral approaches to nuclear fuel cycle in Asian-Pacific region countries that are proposed by the University of Tokyo. In particular, the following factors are embedded into each type: A) no involvement of assurance of services, B) provision of assurance of services including construction of new facility, without transfer of ownership, and C) provision of assurance of service including construction of new joint facilities with ownership transfer of facilities to multilateral nuclear fuel cycle approach. We show the overnight costs taking into account install and operation of nuclear fuel cycle facilities for each option. The economic parameter values such as uranium price, scale factor, and market output expansion influences the total cost for each option. Thus, we show how these parameter values and economic risks affect the total overnight costs for each option. Additionally, the international facilities could increase the risk of transportation for nuclear material compared to national facilities. We discuss the potential effects of this transportation risk on the costs for each option. (author)
Thomson, D. J.; Maclennan, C. G.; Lanzerotti, L. J.
The EPAM charged particle instrument on ACE is the backup for the HISCALE instrument on Ulysses making the two ideally suited for spatial coherence studies over large heliosphere distances. Fluxes of low-energy ( ~50 - 200 keV) electrons are detected in eight spatial sectors on both spacecraft. A spherical harmonic description of the particle flux as a function of time using only the l=0 and l=1 degree coefficients describes most of the observed flux. Here we concentrate on the three l=1 coefficients for the 60--100 kev electrons.Between the two spacecraft these result in nine coherence estimates that are all typically moderately coherent, but the fact that the different coefficients at each spacecraft are also coherent with each other makes interpretation difficult. To avoid this difficulty we estimated the canonical coherences between the two groups of three series. This, in effect, chooses an optimum coordinate system at each spacecraft and for each frequency and estimates the coherence in this frame. Using one--minute data, we find that the canonical coherences are generally larger at high frequencies (3 mHz and above) than they are at low frequencies. This appears to be generally true and does not depend particularly on time, range, etc. However, if the data segment is chosen too long, say > 30 days with 1--minute sampling, the coherence at high frequencies drops. This may be because the spatial and temporal features of the mode are confounded, or possibly because the solar modes p--modes are known to change frequency with solar activity, so do not appear coherent on long blocks.The coherences are not smooth functions of frequency, but have a bimodal distribution particularly in the 100 μHz to 5 mHz range. Classifying the data at frequencies where the canonical coherences are high in terms of apparent polarization and orientation, we note two major families of modes that appear to be organized by the Parker spiral. The magnetic field data on the two
The paper proposes to ground the taxonomy of economic systems on the identification of strongly performative institutions as distinctive features. I analyse performativity on the basis of the Aoki model of institutions, enriched by current approaches to performativity, which I combine with Searle's notion of a status function. Performativity is conceived as resulting from the conjunction of public representations (sign systems) and behavioral dispositions which channel strategic interactions ...
Schelleman, H; Klungel, O H; van Duijn, C M; Witteman, J C M; Hofman, A; de Boer, A; Stricker, B H Ch
AIMS: We investigated whether the insertion/deletion (I/D) polymorphism of the ACE gene modified the adherence to ACE inhibitors as measured by the discontinuation of an ACE inhibitor, or addition of another antihypertensive drug. METHODS: This was a cohort study among 239 subjects who started ACE i
Luis M. Abadie
Full Text Available This paper deals with the economics of gasification facilities in general and IGCC power plants in particular. Regarding the prospects of these systems, passing the technological test is one thing, passing the economic test can be quite another. In this respect, traditional valuations assume constant input and/or output prices. Since this is hardly realistic, we allow for uncertainty in prices. We naturally look at the markets where many of the products involved are regularly traded. Futures markets on commodities are particularly useful for valuing uncertain future cash flows. Thus, revenues and variable costs can be assessed by means of sound financial concepts and actual market data. On the other hand, these complex systems provide a number of flexibility options (e.g., to choose among several inputs, outputs, modes of operation, etc.. Typically, flexibility contributes significantly to the overall value of real assets. Indeed, maximization of the asset value requires the optimal exercise of any flexibility option available. Yet the economic value of flexibility is elusive, the more so under (price uncertainty. And the right choice of input fuels and/or output products is a main concern for the facility managers. As a particular application, we deal with the valuation of input flexibility. We follow the Real Options approach. In addition to economic variables, we also address technical and environmental issues such as energy efficiency, utility performance characteristics and missions (note that carbon constraints are looming. Lastly, a brief introduction to some stochastic processes suitable for valuation purposes is provided.
This article argues that the relatively new field of personnel economics (PE) holds strong potential as a tool for studying public sector workforces. This subfield of labor economics is based on a strong foundation of microeconomics, which provides a robust theoretical foundation for studying workforce and organizational design issues. PE has evolved on this foundation to a strong practical emphasis, with theoretical insights designed for practical use and with strong focus on empirical research. The field is also characterized by creative data entrepreneurship. The types of datasets that personnel economists use are described. If similar datasets can be obtained for public sector workforces, PE should be a very useful approach for studying them. PMID:19829236
Timchuk Boris S.
The article deals with the essence of economic policy as a science, analyzes the two-century transformation of the economic policy, offers a versatile approach to determination of the economic policy in the New economy.
Full Text Available In the article, the need of transition to the rational subsoil use (the alternative mining approach is proved, which unlike general one supposes the increasing of extraction rate of valuable components in the deposit and multiple use of raw materials, the maximizing recycling, the decreasing of land occupation, the increasing of the development period of deposit at some income decrease up to the moderate level, which is enough to provide the attraction for investors. The multicriteriality is considered as the crucial principle of rational subsoil use at taking management decisions, i.e. the considering of ecological, economic and social targets, aimed at receiving moderate profit at proper social and environmental standards. The graphic representation of models of the general mining approach and the alternative one allows to emphasize the specified advantages of transition to rational subsoil resources development and reflect them in design equation. In the paper, three performance strategies providing the implementation of the alternative approach are offered: full-field development, application ecologically and economically effective systems and the development processes, consideration of reclamation and minimization of long term environmental effects of mining
This paper deals with the economics of gasification facilities in general and Integrated Gasification Combined Cycle (IGCC) power plants in particular. Regarding the prospects of these systems, passing the technological test is one thing, passing the economic test can be quite another. In this respect, traditional valuations assume constant input and/or output prices. Since this is hardly realistic, we allow for uncertainty in prices. We naturally look at the markets where many of the products involved are regularly traded. Futures markets on commodities are particularly useful for valuing uncertain future cash flows. Thus, revenues and variable costs can be assessed by means of sound financial concepts and actual market data. On the other hand, these complex systems provide a number of flexibility options (e.g., to choose among several inputs, outputs, modes of operation, etc.). Typically, flexibility contributes significantly to the overall value of real assets. Indeed, maximization of the asset value requires the optimal exercise of any flexibility option available. Yet the economic value of flexibility is elusive, the more so under (price) uncertainty. And the right choice of input fuels and/or output products is a main concern for the facility managers. As a particular application, we deal with the valuation of input flexibility. We follow the Real Options approach. In addition to economic variables, we also address technical and environmental issues such as energy efficiency, utility performance characteristics and emissions (note that carbon constraints are looming). Lastly, a brief introduction to some stochastic processes suitable for valuation purposes is provided. (author)
Levina R. S.
This article emphasizes the need to develop methodologies through applying valid economic knowledge within research approaches used in writing final and PhD theses in order to apply this knowledge in the development of entrepreneurship in the context of model approaches. The proposed methodological approach in the field of economic education contributes to the training of highly qualified specialists in economics.
Pradeep Kumar Arora* and Ashish Chauhan
Hypertension is a chronic increase in blood pressure, characterized as primary and secondary hypertension. The disorder is associated with various risk factors like obesity, diabetes, age, lack of exercise etc. Hypertension is being treated since ancient times by Ayurvedic, Chinese and Unani medicine. Now various allopathic drugs are available which include diuretics, calcium channel blockers, α-blockers, β-blockers, vasodilators, central sympatholytics and ACE-inhibitors. Non-pharmacological...
Full Text Available Modern society is characterised not only by a fascination with scientific technology as a means of solving all problems, especially those that stand in the way of material progress (technicism, but also by an obsessive interest in everything that has to do with money (economism or mammonism. The article discusses the relationship between technicism and economism, on the basis of their relationship to utilitarian thinking: the quest for the greatest happiness for the greatest number of people. Recent major studies of neo-liberalism (seen as an intensification of utilitarianism by Laval and Dardot are used as reference to the development of utilitarianism. It is suggested that the western view of the world, as expressed in economism and technicism, with a utilitarian ethics, features three absolutisations: those of theoretical thinking, technology and economics. In a second part, the article draws on the framework of reformational philosophy to suggest an approach that, in principle, is not marred by such absolutisations.
Greenbaum, Daniel; Costantini, Maria; Van Erp, Annemoon; Shaikh, Rashid; Bailey, Brent; Tennant, Chris; Khalek, Imad; Mauderly, Joe; McDonald, Jacob; Zielinska, Barbara; Bemis, Jeffrey; Storey, John; Hallberg, Lance; Clark, Nigel
The objective of the Advanced Collaborative Emissions Study (ACES) was to determine before widespread commercial deployment whether or not the new, energy-efficient, heavy duty diesel engines (2007 and 2010 EPA Emissions Standards Compliant) may generate anticipated toxic emissions that could adversely affect the environment and human health. ACES was planned to take place in three phases. In Phase 1, extensive emissions characterization of four production-intent prototype engine and control systems designed to meet 2007 standards for nitrogen oxides (NOx) and particulate matter (PM) was conducted at an existing emissions characterization facility: Southwest Research Institute (SwRI). One of the tested engines was selected (at random, after careful comparison of results) for health testing in Phase 3. In Phase 2, extensive emission characterization of three production-intent prototype engine and control systems meeting the 2010 standards (including more advanced NOx controls to meet the more stringent 2010 NOx standards) was conducted at the same test facility. In Phase 3, one engine/aftertreatment system selected from Phase 1 was further characterized during health effects studies (at an existing inhalation toxicology laboratory: Lovelace Respiratory Research Institute, [LRRI]) to form the basis of the ACES safety assessment. The Department of Energy (DOE) award provided funding for emissions characterization in Phases 1 and 2 as well as exposure characterization in Phase 3. The main health analyses in Phase 3 were funded separately and are not reported here.
Full Text Available A quantitative structure-activity relationship (QSAR model of angiotensin-converting enzyme- (ACE- inhibitory peptides was built with an artificial neural network (ANN approach based on structural or activity data of 58 dipeptides (including peptide activity, hydrophilic amino acids content, three-dimensional shape, size, and electrical parameters, the overall correlation coefficient of the predicted versus actual data points is =0.928, and the model was applied in ACE-inhibitory peptides preparation from defatted wheat germ protein (DWGP. According to the QSAR model, the C-terminal of the peptide was found to have principal importance on ACE-inhibitory activity, that is, if the C-terminal is hydrophobic amino acid, the peptide's ACE-inhibitory activity will be high, and proteins which contain abundant hydrophobic amino acids are suitable to produce ACE-inhibitory peptides. According to the model, DWGP is a good protein material to produce ACE-inhibitory peptides because it contains 42.84% of hydrophobic amino acids, and structural information analysis from the QSAR model showed that proteases of Alcalase and Neutrase were suitable candidates for ACE-inhibitory peptides preparation from DWGP. Considering higher DH and similar ACE-inhibitory activity of hydrolysate compared with Neutrase, Alcalase was finally selected through experimental study.
Full Text Available The paper studies the categorical-conceptual apparatus of risk and its refinement based on a critical analysis of existing systematic scientific approaches. Determined that in the refinement of the economic nature of the risk of a number of controversial issues: the definition of the objective or subjective nature of risk; matching of concepts such as «risk», «danger», «loss», «probability of loss»; definition of negative or positive consequences of risk; identification of risk with its consequences, or source of origin, which makes the relevance of research topics. As a result of scientific research has been refined interpretation of risk as an economic category, the characteristics of the company associated with the probability of unforeseen situations that may lead to negative and positive impacts, assessment of which requires the development of alternatives for management decisions. Clarification of the definition focuses on the possibility (probability of a favorable (unfavorable events which require certain corrective action management unit of the enterprise. The author emphasizes the mandatory features of the category of «risk», in particular: the concept of risk is always associated with the uncertainty of the future; event occurring has implications for the enterprise (both negative and positive; consequences for necessitates the development of a number of alternative solutions to the possible elimination of the negative consequences of risky events; risk – a mandatory attribute of modern management (its value is enhanced in terms of market conditions; subject to risk assessment and management by the company. Dedicated and updated features contribute to the clarification of the nature of the economic risk and categorical conceptual apparatus of risk management.
Lima Dênis Pires de
Full Text Available This report outlines the discovery, the design and development of new compounds, and, structure-activity relationships for this drug category. Updated approaches to planned syntheses of new worthy ACE-inhibitors are also exploited.
Turyshev, Slava G; Toth, Viktor T
We develop a high-precision model for relativistic observables of the Atomic Clock Ensemble in Space (ACES) experiment on the International Space Station (ISS). We develop all relativistic coordinate transformations that are needed to describe the motion of ACES in Earth orbit and to compute observable quantities. We analyze the accuracy of the required model as it applies to the proper-to-coordinate time transformations, light time equation, and spacecraft equations of motion. We consider various sources of nongravitational noise and their effects on ACES. We estimate the accuracy of orbit reconstruction that is needed to satisfy the ACES science objectives. Based on our analysis, we derive models for the relativistic observables of ACES, which also account for the contribution of atmospheric drag on the clock rate. We include the Earth's oblateness coefficient $J_2$ and the effects of major nongravitational forces on the orbit of the ISS. We demonstrate that the ACES reference frame is pseudo-inertial at th...
Gheorghe Săvoiu; Constantin Manea
The main aim of this paper is to attempt a theoretical delineation of a new econoscience now known as financial econometrics, which is as a result of a dual approach, one originally from economics to econometrics, followed by another one, articulate, from financial economics to financial econometrics, both purely theoretical, simultaneously stressing the importance of economic and financial modelling, historically detailing the emergence and development of this new econoscience, outlining its...
Full Text Available The resolution of the environmental/economic dispatch (EED problem using the different methods which are proposed in literature consumes an important computing time. Thus, the present paper deals with a technique based on two steps to solve the EED problem of electric energy power in real-time for forecast load curve. The first step uses the NSGAII approach (Non-dominated Sorting Genetic Algorithm to solve the multi-objective problem MOP for different levels of load by treating the two cases, problem without line constraints and with line constraints. To verify effectiveness of this approach, NSGAII is compared with other algorithms which are used in the literature. Such as, weighted sum method (WSM, NPGA (Niched Pareto Genetic Algorithm, NSGA and SPEA (Strength Pareto Evolutionary Algorithm. To exploit the results in real time for forecast load curve, second step uses a radial basis function neural network (RBFN with 3 layers, input layer formed by the level of global load, hidden layer and output layer formed by the generations of the various machines. The validity and effectiveness of this technique are verified by an example of a load curve of a didactic electric network IEEE 30-bus system with 6-generating units.
Dr. Anastasios Alexandridis
Full Text Available The analysis of international policy co-ordination has been a major growth area within macroeconomics for the past twenty years. It has, however, developed in a confused way, combining approaches from a number of areas of economic theory and being forced to confront the gap between that theory and international political economy. At the same time, basic approaches to the desirability of increased co-ordination often remain embedded in the original attitudes of participants towards domestic macroeconomic policy. This relates most obviously to issues such as the desirability of government management of the economy and the nature of the exchange rate system. The result has been that we now have an increasingly well-developed, highly technical body of literature which, with some interesting exceptions, supports the idea of increased international macroeconomic policy co-ordination, while remaining cautious about the size of the gains which will come from it. At the same time, uncertainty remains over the precise meaning of several of the terms used in the field and, more importantly, over the interpretation of the outcomes of international conferences and the actions of governments. This latter uncertainty relates not just to the likely consequences of policy actions but even to the motives for them. It is this contrast between the smooth surface of theory and the unevenness of historical events which we wish to capture here
Wang, Bin; Liu, Juanjuan; Wang, Shudong; Cheng, Wei; Juan, Liu; Liu, Chengsi; Xiao, Qingnong; Kuo, Ying-Hwa
Four-dimensional variational data assimilation (4DVar) is one of the most promising methods to provide optimal analysis for numerical weather prediction (NWP). Five national NWP centers in the world have successfully applied 4DVar methods in their global NWPs, thanks to the increment method and adjoint technique. However, the application of 4DVar is still limited by the computer resources available at many NWP centers and research institutes. It is essential, therefore, to further reduce the computational cost of 4DVar. Here, an economical approach to implement 4DVar is proposed, using the technique of dimensionreduced projection (DRP), which is called "DRP-4DVar." The proposed approach is based on dimension reduction using an ensemble of historical samples to define a subspace. It directly obtains an optimal solution in the reduced space by fitting observations with historical time series generated by the model to form consistent forecast states, and therefore does not require implementation of the adjoint of tangent linear approximation. To evaluate the performance of the DRP-4DVar on assimilating different types of mesoscale observations, some observing system simulation experiments are conducted using MM5 and a comparison is made between adjoint-based 4DVar and DRP-4DVar using a 6-hour assimilation window.
H. Schelleman (Hedi); O.H. Klungel (Olaf); C.M. van Duijn (Cock); J.C.M. Witteman (Jacqueline); A. Hofman (Albert); A. de Boer (Anthonius); B.H.Ch. Stricker (Bruno)
textabstractAims: We investigated whether the insertion/deletion (I/D) polymorphism of the ACE gene modified the adherence to ACE inhibitors as measured by the discontinuation of an ACE inhibitor, or addition of another antihypertensive drug. Methods: This was a cohort study among 239 subjects who s
Bower, M; Brock, C; Holden, L; Nelstrop, A; Makey, A R; Rustin, G J; Newlands, E S
Mediastinal germ cell tumours (MGCT) are rare and most published series reflect the experiences of individual institutions over many years. Since 1979, we have treated 16 men (12 non-seminomatous germ cell tumours and 4 seminomas) with newly diagnosed primary MGCT with POMB/ACE chemotherapy and elective surgical resection of residual masses. This approach yielded complete remissions in 15/16 (94%) patients. The median follow-up was 6.0 years and no relapses occurred more than 2 years after treatment. The 5 year overall survival in the non-seminomatous germ cell tumours (NSGCT) is 73% (95% confidence interval 43-90%). One patient with NSGCT developed drug-resistant disease and died without achieving remission and 2 patients died of relapsed disease. In addition, 4 patients with bulky and/or metastatic seminoma were treated with POMB/ACE. One died of treatment-related neutropenic sepsis in complete remission and one died of relapsed disease. Finally, 4 patients (2 NSGCT and 2 seminomas) referred at relapse were treated with POMB/ACE and one was successfully salvaged. The combination of POMB/ACE chemotherapy and surgery is effective management for MGCT producing high long-term survival rates. PMID:9291802
Kyer, Ben L.; Maggs, Gary E.
Contends that supply-side economics has generated a long-standing debate in both academic and political circles. Discusses the concepts of supply-side economics and how it is represented by the Laffer Curve. Illustrates the use of graphic analysis of tax rates and revenue to show the Laffer effect and supply-side economics. (CFR)
Full Text Available Economic Informatics originates in the industry economy and the electronic processing of information. A clear distinction is made between IT and economic informatics, and further between general and particular economic informatics (the particular economic informatics meaning administration, industrial informatics etc. Economic informatics is deemed to be an applicative science relating to the conception, working modality and representation of IT and communication systems, oriented towards companies which are using electronic computers. This paper pursues to integrate applications allowing the information systems to interconnect at informational level, by information sharing, and at service level, considering the control of the related processes in real time.
Wen-Yeh Hsieh, Tang-Ching Kuan, Kun-Shan Cheng, Yan-Chiou Liao, Mu-Yuan Chen, Pei-Heng Lin, Yuan-Chang Hsu, Chen-Yi Huang, Wei-Hua Hsu, Sheng-Yao Yu, Chih-Sheng Lin
Full Text Available Objective: Pleural effusion is common problem, but the rapid and reliable diagnosis for specific pathogenic effusions are lacking. This study aimed to identify the diagnosis based on clinical variables to differentiate pleural tuberculous exudates from other pleural effusions. We also investigated the role of renin-angiotensin system (RAS and matrix metalloproteinase (MMPs in the pathogenesis of pleural exudates.Experimental design: The major components in RAS and extracellular matrix metabolism, including angiotensin converting enzyme (ACE, ACE2, MMP-2 and MMP-9 activities, were measured and compared in the patients with transudative (n = 45 and exudative (n = 80 effusions. The exudative effusions were come from the patients with tuberculosis (n = 20, pneumonia (n = 32, and adenocarcinoma (n = 28.Results: Increased ACE and equivalent ACE2 activities, resulting in a significantly increased ACE/ACE2 ratio in exudates, were detected compared to these values in transudates. MMP-9 activity in exudates was significantly higher than that in transudates. The significant correlation between ACE and ACE2 activity that was found in transudates was not found in exudates. Advanced analyses showed significantly increased ACE and MMP-9 activities, and decreased ACE2 activity in tuberculous pleural effusions compared with those in pneumonia and adenocarcinoma effusions. The results indicate that increased ACE and MMP-9 activities found in the exudates were mainly contributed from a higher level of both enzyme activities in the tuberculous pleural effusions.Conclusion: Interplay between ACE and ACE2, essential functions in the RAS, and abnormal regulation of MMP-9 probably play a pivotal role in the development of exudative effusions. Moreover, the ACE/ACE2 ratio combined with MMP-9 activity in pleural fluid may be potential biomarkers for diagnosing tuberculous pleurisy.
Nicolai J. Foss
Full Text Available As the transaction cost theory of the firm was taking shape in the 1970s, another important movement in economics was emerging: a revival of the ‘Austrian’ tradition in economic theory associated with such economists as Ludwig von Mises and F. A. Hayek (1973; Dolan, 1976; Spadaro, 1978. As Oliver Williamson has pointed out, Austrian economics is among the diverse sources for transaction cost economics. In particular, Williamson frequently cites Hayek (e.g., Williamson, 1985, p. 8; 1991, p. 162, particularly Hayek’s emphasis on adaptation as a key problem of economic organisation (Hayek, 1945. Following Williamson’s lead, a reference to Hayek’s ‘The Use of Knowledge in Society’ (Hayek, 1945 has become almost mandatory in discussions of economic organisation (e.g., Ricketts, 1987, p. 59; Milgrom and Roberts, 1992, p. 56; Douma and Schreuder 1991, p. 9. However, there are many other potential links between Austrian and transaction cost economics that have not been explored closely and exploited.This article argues that characteristically Austrian ideas about property, entrepreneurship, economic calculation, tacit knowledge, and the temporal structure of capital have important implications for theories of economic organisation, transaction cost economics in particular. Austrian economists have not, however, devoted substantial attention to the theory of the firm, preferring to focus on business-cycle theory, welfare economics, political economy, comparative economic systems, and other areas. Until recently the theory of the firm was an almost completely neglected area in Austrian economics, but over the last decade, a small Austrian literature on the firm has emerged. While these works cover a wide variety of theoretical and applied topics, their authors share the view that Austrian insights have something to offer students of firm organisation.
Hamming, I.; van Goor, H.; Turner, A. J.; Rushworth, C. A.; Michaud, A. A.; Corvol, P.; Navis, G.
Angiotensin-converting enzyme (ACE) 2 is thought to counterbalance ACE by breakdown of angiotensin (Ang) II and formation of Ang(1-7). Both enzymes are highly expressed in the kidney, but reports on their regulation differ. To enhance our understanding of the regulation of renal ACE and ACE2, we inv
Moreno-Cruz, Juan; Taylor, M. Scott
This paper sets out a simple spatial model of energy exploitation to ask how the location and productivity of energy resources may affect the distribution of economic activity around the globe. This is a very large research question, and we take one small step towards answering it by combining elements from resource and energy economics into one framework that links the spatial productivity of energy sources (both renewable and non-renewable) to the incentives for economic activity to concent...
Mosab I. Tabash; Raj S. Dhankar
This paper explores empirically the relationship between the development of Islamic finance system and economic growth and its direction in Qatar. Using econometric analysis, annually time-series data of economic growth and Islamic banks’ financing from 1990 to 2008 were used. We use Islamic banks’ financing funds given by Islamic banks as a proxy for the development of Islamic finance system and Gross Domestic Product (GDP), and Gross Fixed Capital Formation (GFCF) as proxies for real econom...
Halkos, George; Tzeremes, Nickolaos
This paper by using Data Envelopment Analysis (DEA) and statistical inference evaluates the citation performance of 229 economic journals. The paper categorizes the journals into four main categories (A to D) based on their efficiency levels. The results are then compared to the 27 “core economic journals” as introduced by Dimond (1989). The results reveal that after more than twenty years Diamonds’ list of “core economic journals” is still valid. Finally, for the first time the paper uses da...
Ronghai He; Haile Ma; Weirui Zhao; Wenjuan Qu; Jiewen Zhao; Lin Luo; Wenxue Zhu
A quantitative structure-activity relationship (QSAR) model of angiotensin-converting enzyme- (ACE-) inhibitory peptides was built with an artificial neural network (ANN) approach based on structural or activity data of 58 dipeptides (including peptide activity, hydrophilic amino acids content, three-dimensional shape, size, and electrical parameters), the overall correlation coefficient of the predicted versus actual data points is = 0 . 9 2 8 , and the model was applied in ACE-inhibitory ...
Beylot, Antoine; Boitier, Baptiste; Lancesseur, Nicolas; Villeneuve, Jacques
In a context of waste management policies aimed at promoting waste prevention and recycling and, conversely, reducing waste landfilling, this study investigates how waste is generated and treated in a consumption perspective. A Waste Input-Output Analysis is implemented that considers 14 waste fractions and four waste management techniques. Input-Output Tables extended to wastes are initially compiled for the year 2008 considering France and five of its main import suppliers, and further completed with data on waste treatment. Wastes from economic activities are accordingly reallocated to the product categories of household consumption that induce their production. In particular, considering five waste categories (dry recyclable wastes, mixed wastes, mineral wastes, organic wastes, and total wastes) as an aggregation of the 14 waste fractions studied, the ten product categories with the highest contribution account for 64-86% of the total generation of wastes. Waste intensity and volume of expenses are analyzed as the drivers for the amounts of wastes induced by each product category. Similarly, the products responsible for the largest amounts of waste landfilling and incineration without energy recovery, i.e. the management techniques at the bottom of the "waste management hierarchy", are identified. Moreover, this study highlights the relative importance of waste produced abroad as compared to that produced in France, regarding the total amount of waste induced by French household consumption. The sensitivity of results to the modeling of import production is subsequently discussed. Finally, the potential perspectives for this type of consumption approach are considered with respect to its utility and current limitations in a context of waste policy planning, and more particularly regarding the way waste policy targets are set. PMID:26851169
Full Text Available The main aim of this paper is to attempt a theoretical delineation of a new econoscience now known as financial econometrics, which is as a result of a dual approach, one originally from economics to econometrics, followed by another one, articulate, from financial economics to financial econometrics, both purely theoretical, simultaneously stressing the importance of economic and financial modelling, historically detailing the emergence and development of this new econoscience, outlining its subject and objectives, and describing some of the most commonly used methods and models, while noting the presence of increasingly sharp competition of econophysics, sociophysics and economy quantum, in the universe of modelling the processes and phenomena in classical economics and financial economics.
Blanco Fonseca, Maria; Ramos, Fabien; Van Doorslaer, Benjamin
Projections for world food production and prices play a crucial role to evaluate and tackle future food security challenges. Understanding how these projections will be affected by climate change is the main objective of this study. By means of a bio-economic approach we assess the economic impacts of climate change on agrifood markets, providing both a global analysis and a regionalised evaluation within the EU. To account for uncertainty, we analyse the IPCC emission scenario A1B for the 20...
Highlights: • For fast and exact broadening of the ACE data tables, we used a new broadening algorithm. • A new code called FDBACE has been developed which generates high temperature ACE files. • This code can be easily converted to a module for using internally in Monte Carlo code. • A parallel algorithm is used for fast broadening based on shared memory scheme. - Abstract: In this article we introduce a code called FDBACE (Fast Doppler Broadening ACE) which has been developed as a tool for MCNP users to enhance the generation of high temperature ACE data tables. In this code, we developed new broadening, thinning and unionization subroutines, implemented in FORTRAN programming language, for directly broadening the ACE data table at desired temperature. For fast and exact broadening of the ACE data tables, we used a new parallel broadening algorithm based on the kernel broadening approach and shared memory scheme (using OpenMP). The thermal scattering table for molecules and crystalline solids, and probability table for unresolved resonances are computed by interpolating data between two bracketing temperatures. This code, which reads the ACE data table file and broadens it to the desired temperature and then writes it to a new ACE data table file, can be easily converted to an internal module embedded in Monte Carlo source code for In-line Doppler broadening. Accuracy, performance and formatting of FDBACE are evaluated for validation of the proposed method by three different test cases. The results obtained from FDBACE code, shows that it has a good performance over previous codes such as NJOY, SIGACE and MAKXSF in generating high temperature ACE data tables
Vicente Caballero de la Torre
Full Text Available This paper presents the origin of the issue of empathy in the History of Ideas and its importance in economics, as well as its revitalization. It concludes that it is not the study of empathy, so fashionable today, but the study of decision making the place where Economics can find the nature of emotions in relation to human behavior. This nature is its power to inhibit behavior. The study of repentance is itself more interesting and helpful for the economy than the study of empathy. Finally, the institutional approach is presented as the best in order to understand the issues related to economic human behavior
This article explores the application of economic theory to the measurement of growth in public service output. This approach is designed to take account of changes in the quality of the output. The article discusses two alternative economic approaches; the basic expenditure determinants approach and the use of outcome production functions. The article demonstrates how the approaches could work in practice with ahypothetical example of expenditure and outcome production functions for police s...
Van Galen, Dean; Schneider-Rebozo, Lissa; Havholm, Karen; Andrews, Kris
This chapter presents the state of Wisconsin and the University of Wisconsin System as an ongoing case study for best practices in systematic, intentional, statewide programming and initiatives connecting undergraduate research and economic development.
Raymond Franck; Francois Melese; John Dillard
Proceedings Paper (for Acquisition Research Program) This study examines defense acquisition through the new lens of Transaction Cost Economics (TCE). TCE is an emergent field in economics that has multiple applications to defense acquisition practices. TCE''s original focus was to guide ''make-or-buy?'' decisions that define the boundaries of a firm. This study reviews insights afforded by TCE that impact government outsourcing (''buy'' decisions), paying special attention to defense pro...
Rodriguez Acosta, Mauricio
This dissertation consists of four chapters in Political Economy and Resource Economics from a macroeconomic perspective. This collection of works emphasizes the endogenous nature of institutions and their importance for economic development. The four chapters revolve around two central questions: 1. Why do inefficient institutions emerge and persist over time? And, 2. What are the dynamic consequences of inefficient institutions? The first two chapters investigate these two central questions...
OBJECTIVES OF THE STUDY: This thesis has three main objectives. To provide a thorough review of the theoretical foundation of corruption in economics, introduce the methodologies and their main results and lastly design an economic corruption experiment addressing mechanics and importance of reciprocity for individuals in comparison to other moral costs of corruption. THEORETICAL FOUNDATION: Theoretical foundation reviewed in the thesis comprises of both theoretical and practical ...
Sequeira, Tiago Neves; Campos, Carla
On average, tourism-specialized countries grow more than others. This fact is inconsistent with economic theory as, in particular, endogenous growth theory suggests that economic growth is linked with: (1) sectors with high intensity in R&D and thus high productivity; (2) large scale. In this paper, we use panel data methods to go further in treating the endogeneity problem. In general and contrary to previous works, we conclude that tourism, on its own, cannot explain the higher growth rates...
A. Berezhna; Yu. Popova
The urgent for today problem of socio-economic development of cities of Ukraine is explored there. Modeling is the methodological basis of research.On the basis of the detailed analysis of works of domestic and foreign scientists in the field of socio-economic development there has been defined basic types of models (linear, partial improvement, multiple-line, actor, structural), generalized the developments in relation to territorial development, to which in particular belong: analysis of fu...
Cristiano Perugini; Gaetano Martino
Towards an Interpretation of Economic Inequality in Rural Areas: a Conceptual and Empirical Approach (by Gaetano Martino and Cristiano Perugini) - ABSTRACT: Department of Economic Sciences and Rural Appraisal, University of Perugia 1 Department of Economics, Finance and Statistics, University of Perugia 2 (Paper first received, April 2005; in final form, April 2006) Abstract Economic inequality among European regions has been widely investigated, and a large number of empirical results have e...
Priddat, Birger P.
Only a few economists knew about hermeneutical economics. But my request is to confirm hermeneutical economics only for the reason to make it criticable. Without any doubt, hermeneutical economics is worth to be criticized; but it is an incomplete approach. The first part presents Ludwig M. Lachmann's version of hermeneutical economics. Lachmann is picked up from the scenario of hermeneutical economists (i.e. Ebeling, Berger, Lavoie, some authors of Kirzner 1986, etc.), because he is the most...
Jaiswal, Kishor; Wald, David J.
We extended the U.S. Geological Survey's Prompt Assessment of Global Earthquakes for Response (PAGER) empirical fatality estimation methodology proposed by Jaiswal et al. (2009) to rapidly estimate economic losses after significant earthquakes worldwide. The requisite model inputs are shaking intensity estimates made by the ShakeMap system, the spatial distribution of population available from the LandScan database, modern and historic country or sub-country population and Gross Domestic Product (GDP) data, and economic loss data from Munich Re's historical earthquakes catalog. We developed a strategy to approximately scale GDP-based economic exposure for historical and recent earthquakes in order to estimate economic losses. The process consists of using a country-specific multiplicative factor to accommodate the disparity between economic exposure and the annual per capita GDP, and it has proven successful in hindcast-ing past losses. Although loss, population, shaking estimates, and economic data used in the calibration process are uncertain, approximate ranges of losses can be estimated for the primary purpose of gauging the overall scope of the disaster and coordinating response. The proposed methodology is both indirect and approximate and is thus best suited as a rapid loss estimation model for applications like the PAGER system.
Fernández, Francisco J.; Blanco, Maria
The economic effects of climate change on agriculture have been widely assessed in the last two decades. Many of these assessments are based on the integration of biophysical and agro-economic models, allowing to understand the physical and socio-economic responses of the agricultural sector to future climate change scenarios. The evolution of the bio-economic approach has gone through different stages.This review analyses its evolution: firstly, framing the bio-economic approach into the con...
Devkota, Surendra R.
This dissertation analyzes the sustainability of the economy of Nepal. The main empirical question addressed is whether the Tenth Plan of Nepal (2002--2007) will meet its projected economic output goal and achieve its primary goal of reducing poverty. To this end, economic growth scenarios are examined in terms of availability of energy demand and supply, and income disparity among different households. The structure of the Nepali economy is examined using a Leontief input-output table, a Ghosian supply-side input-output table, and a social accounting matrix for the year 1999. Based on the input-output analysis of energy demand and supply for the 10th Plan, it is unlikely that energy requirements of the projected output will be met, unless some extra sources of energy are developed. Households need to switch their energy use from fuel wood/biomass to other alternatives. In order to meet the target of the Plan vis-a-vis energy demand or supply, a few policy measures are urgently needed, though some of these options require many years to develop. Household income inequality and distribution is examined through the SAM multipliers; namely aggregate, transfer, open-loop, and closed-loop multipliers. The investment-income multiplier scenarios for the 10th Plan indicate that the nominal income of households may increase due to the increased investment, which will not necessarily improve the bottom deciles households, particularly socio-economically deprived households. Economic growth in Nepal during the past fifty years demonstrates that the modernization model is unsuccessful. Economic growth occurred at some centers at the cost of periphery. A huge regional disparity has developed between hills and plains, east and west, city and rural areas. Nepal's persistent poverty indicates a failure of modernization theory. The Tenth Plan would be another continuation of a failed legacy, unless social and natural endowments are considered for sustainability. Nepal could be an
Information economics provides important tools to articulate an economics analysis of the governance mechanisms for the generation and exploitation of localized technological knowledge. A variety of hybrid forms of knowledge governance ranging from coordinated transactions and constructed interactions to quasi-hierarchies can be found between the two unrealistic extremes of pure markets and pure organizations. The notion of localized technological knowledge as a highly heterogeneous dynamic p...
William D. Nordhaus
What are the prospects for long-run economic growth? The present study looks at a recently launched hypothesis, which I label Singularity. The idea here is that rapid growth in computation and artificial intelligence will cross some boundary or Singularity after which economic growth will accelerate sharply as an ever-accelerating pace of improvements cascade through the economy. The paper develops a growth model that features Singularity and presents several tests of whether we are rapidly a...
William D. Nordhaus
What are the prospects for long-run economic growth?, the present study looks at a more recently launched hypothesis, which I label Singularity. The idea here is that rapid growth in computation and artificial intelligence will cross some boundary or Singularity after which economic growth will accelerate sharply as an ever-accelerating pace of improvements cascade through the economy. The paper develops a growth model that features Singularity and presents several tests of whether we are rap...
Davis, George C.; Jacob, Jacy; Good, Deborah J.
Food intake is greatly influenced by economic factors. Consequently, neuroeconomics has been identified as a new and important area for understanding the interaction between genotypes and phenotypes related to food intake. A foundational element of economics is choice between alternatives. Changing food choices are a central element in the explanation of the increasing obesity rates in human populations. The purpose of this research is to incorporate the key element of choice into the investi...
Heitor Reis, António; Dionísio, Andreia
This paper illustrates an application of Constructal Theory to spatial economics and Þnance. Constructal theory is about the generation of architecture in ßow systems in general. Simply stated, the constructal law proclaims a tendency to maximize ßow access in time, i.e., for a Þnite-size ßow system to persist in time (to live), it must evolve in such a way that it provides easier access to the currents that ßow through it. Constructal optimization in spatial economics is po...
Zhu, JZ; Irving, MR; Xu, GY
This article presents a new nonlinear convex network flow programming model and algorithm for solving the on-line economic power dispatch with N and N−1 security. Based on the load flow equations, a new nonlinear convex network flow model for secure economic power dispatch is set up and then transformed into a quadratic programming model, in which the search direction in the space of the flow variables is to be solved. The concept of maximum basis in a network flow graph was introduced so tha...
Larissa Margareta BĂTRÂNCEA; Ramona Anca NICHITA; Ioan BĂTRÂNCEA; Bogdan Andrei MOLDOVAN
The paper reviews the models of tax compliance with an emphasis on economic and behavioral perspectives. Although the standard tax evasion model of Allingham and Sandmo and other similar economic models capture some important aspects of tax compliance (i.e., taxpayers’ response to increases in tax rate, audit probability, penalty rate) they do not suffice the need for an accurate prediction of taxpayers’ behavior. The reason is that they do not offer a comprehensive perspective on the sociolo...
Hayek’s contribution to the analysis of law has been widely criticized and disputed. This paper shares with a recent assessment by Beaulier, Boettke and Coyne the opinion that the significance of Hayek’s legal writings and their relevance to law and economics can only be completely understood by jointly analyzing his economic theory and his legal theory. Moreover it will be argued that both theories must be reconsidered in light of Hayek’s theory of mind. This theory, in fact, represents the ...
Full Text Available Collapsed gully erosion constantly plagues the sustainability of rural areas in China. To control collapsed gully erosion, an ecological and economic approach, which uses tree plantation to gain economic benefits and control soil erosion, has been widely applied by local governments in Southern China. However, little is known about the economic feasibility of this new method. The objective of this study was to determine the effectiveness and economic benefits of the new method. Based on a case study in Changting County, Southeast China, two farms were selected to represent a timber tree plantation and a fruit tree plantation, respectively. The Annual Capital Capitalization Method and Return on Investment (ROI were selected to conduct cost-benefit analysis. In contrast to previous studies, we found that the new approach was far from economic. The value of the newly-built forestland in Sanzhou Village and Tufang Village is 2738 RMB ha−1 and 5477 RMB ha−1, respectively, which are extremely lower than the costs of ecological restoration. Meanwhile, the annual ROI is −3.60% and −8.90%, respectively, which is negative and also far poorer than the average value of forestry in China. The costs of conservation were substantially over the related economic benefits, and the investors would suffer from greater loss if they invested more in the conservation. Low-cost terraces with timber trees had less economic loss compared with the costly terraces with fruit tree plantation. Moreover, the cost efficiency of the new approaches in soil conservation was also greatly poorer than the conventional method. The costs of conserving one ton soil per year for conventional method, new method for planting timber trees, and planting fruit trees were 164 RMB, 696 RMB, and 11,664 RMB, respectively. Therefore, the new collapsed gully erosion control methods are uneconomic and unsuitable to be widely carried out in China in the near future.
Responses from 64 of 80 extension agents specializing in community resources and economic development identified the "Journal of the Community Development Society" as the primary source of ideas and information. Frequently cited program topics were entrepreneurship, fiscal policy, budgeting, strategic planning, and leadership development. Among…
Harle, K.M.; Sanfey, A.G.
Although recent economic models of human decision making have recognised the role of emotion as an important biasing factor, the impact of incidental emotion on decisions has remained poorly explored. To address this question, we jointly explored the role of emotional valence (i.e., positive vs. neg
Rao, R. Ramesh; Jani, Rohana
The economic progress made by many countries is attributed to many factors. Education is often quoted as a major contributing factor. There are many researches done in evaluating and determining the role of education in nations. In this paper, factors of education which have helped in the case of Malaysia are dwelled upon. Education has helped…
Full Text Available Does Eastern Germany differ significantly from Western part in economic terms? How have new Bundeslnder been developing over past twenty years? How fast has East been catching up with West? What could have hampered convergence? How today are German states equipped with factors determining future growth? How the new Bundeslnder performed do compared with the old ones? This paper seeks to address above mentioned questions. It offers a comprehensive review of key economic developments of two decades of reunited Germany. Particularly it examines current economic landscape; investigates convergence processes taking place since reunification and tries to identify most likely impediments hampering full catching up. Finally, it aims at assessing contemporary growth potential of German states. With respect to the starting point poor performance of East Germany back in 1990 the progress made and results achieved are impressive. Though, comparing the situation with Western part of the country significant discrepancies continue to exist. Certainly, assessment of the last twenty years of reunited Germany hinges much upon perspective taken. Two decades after Berlin Wall Fall opinions on economic consequences of reunification are more balanced, since much has been achieved, but much still needs to be done.
The goals and measurement strategy of the Aerosol/Cloud/Ecosystems Mission (ACE) are described. ACE will help to answer fundamental science questions associated with aerosols, clouds, air quality and global ocean ecosystems. Specifically, the goals of ACE are: 1) to quantify aerosol-cloud interactions and to assess the impact of aerosols on the hydrological cycle and 2) determine Ocean Carbon Cycling and other ocean biological processes. It is expected that ACE will: narrow the uncertainty in aerosol-cloud-precipitation interaction and quantify the role of aerosols in climate change; measure the ocean ecosystem changes and precisely quantify ocean carbon uptake; and, improve air quality forecasting by determining the height and type of aerosols being transported long distances. Overviews are provided of the aerosol-cloud community measurement strategy, aerosol and cloud observations over South Asia, and ocean biology research goals. Instruments used in the measurement strategy of the ACE mission are also highlighted, including: multi-beam lidar, multiwavelength high spectra resolution lidar, the ocean color instrument (ORCA)--a spectroradiometer for ocean remote sensing, dual frequency cloud radar and high- and low-frequency micron-wave radiometer. Future steps for the ACE mission include refining measurement requirements and carrying out additional instrument and payload studies.
Oleg Sergeevich Sukharev
Full Text Available The subject matter of the article — the development of the doctrine of “coherent” Regional Development and research of the structural quality of the development of regional systems on the basis of theoretical analysis of institutional factors (parameters that determine the manufacturability of the regional economy. The purpose of the research — to show the possibilities of technological change and shift of economic growth in a particular regional system, with stringent limits for accelerated development, with an emphasis on industrial regions. To this end, formed a number of structural models and analyze the impact of technological factors on the growth parameters of the regional economy, the definition of conditions for the development of the industrial region. Methodology. The correlation and regression analysis are applied, which allows to establish a statistically significant relationship between the relevant parameters, the econometric models are used to demonstrate the possibility of estimating the growth parameters via the control parameters, including the technological factor. The structural aspect of regional economic growth is taken into account by the division of investment on the old and new technologies. Result and scope of the research. Increasing adaptability of the regional economy is possible at the expense of compounding results in the use of (old and the application of new technologies. This principle specifies the algorithm of formation of regional development priorities, provides a choice of strategy of technological development of the regional system. Investing resources only in the field of new technologies can dramatically enhance the disparity of regional economic system, the parameters of diversion of resources and the creation of a new resource will determine the pace of growth in the region. Conclusions. Dynamics of investment into old technology provides a major impact on the rate of economic growth in the
The economic evaluation of fusion research to date has focussed on the benefits of essentially unlimited energy for future generations. In this paper it is shown that energy research in general, and fusion research in particular, also provides benefits in the short term, benefitting us today as well as future generations. Short-term benefits are the result of two distinct aspects of fusion research. First, fusion research provides information for decision making on both the continuing fusion research efforts and on other energy research programs. Second, fusion research provides an expectation of a future energy source thereby promoting accelerated consumption of existing fossil fuels today. Both short-term benefits can be quantitatively evaluated and both are quite substantial. Together, these short-term benefits form the primary economic rationale for fusion research
Dougan, James D.
Economic theory predicts an inverse relationship between the quantity of a commodity supplied to the marketplace and the equilibrium market price of that commodity. This prediction was tested in three experiments. Pigeons responded on simple variable-interval schedules, and quantity of reinforcement supplied was varied in a different way in each experiment. In Experiment 1, quantity supplied was varied by manipulating reinforcement rate while keeping session length constant. In Experiment 2, ...
Ríos, Sergio Daniel
Microalgae oil has been identified as a reliable resource for biodiesel production due to its high lipid productivity and potential cultivation in non-fertile locations. However, high scale production of microalgae based biodiesel depends on the optimization of the entire process to be economically feasible. The present work combine the optimization of microalgae downstream processes with computational tools for the modeling of different scenarios of the harvesting, oil extraction and transes...
Kwan Soo Kim
This paper ï¬ rst develops the model, based on endogenous growth argument, in which environmental quality is included as input and thus makes possible the explanation of issues related to resource allocation and its impacts on the environment. Second, it analyzes the relationship between land market performance and underinvestment by incorporating information about soil quality into the analytical framework It extends existing literature on the economic modelling of soil conservation in sever...
This paper extends the notion of the rational agent in economics by acknowledging the role of the unconscious in the agent�s decision-making process. It argues that the unconscious can be modelled by a rational agent with his own objective function and set of information. The combination of both the conscious and unconscious agents is called the "dual agent". This dual agent presents rationally biased behaviors that may not disappear through aggregation, and could be potentially measured. It ...
A different intermodal transportation model based on cost analysis considering technical, economical, and operational parameters is presented. The model consists of such intermodal modes as sea-road, sea-railway, road-railway, and multimode of sea-road-railway. A case study of cargo transportation has been carried out by using the suggested model. Then, the single road transportation mode has been compared to intermodal modes in terms of transportation costs. This comparison takes into accoun...
Chiswick, Carmel Ullman
An economic theory of immigration and immigrant absorption for a religious minority is developed and applied to Jewish history. Human capital is classified according to whether it is allocative or productive, transferable or location-specific, general or Jewish. Crossclassifying these categories leads to various hypotheses about self-selection among Jewish immigrants and their influence on the Jewish community in their destination. Complementarity between general and Jewish human capital is a...
Wiśniewski, Marcin; Jaros, Sławomir; Bąska, Piotr; Cappello, Michael; Długosz, Ewa; Wędrychowicz, Halina
Hookworms are intestinal nematodes that infect up to 740 million people, mostly in tropical and subtropical regions. Adult worms suck blood from damaged vessels in the gut mucosa, digesting hemoglobin using aspartic-, cysteine- and metalloproteases. Targeting aspartic hemoglobinases using drugs or vaccines is therefore a promising approach to ancylostomiasis control. Based on homology to metalloproteases from other hookworm species, we cloned the Ancylostoma ceylanicum metalloprotease 7 cDNA (Ace-mep-7). The corresponding Ace-MEP-7 protein has a predicted molecular mass of 98.8 kDa. The homology to metallopeptidases from other hookworm species and its predicted transmembrane region support the hypothesis that Ace-MEP-7 may be involved in hemoglobin digestion in the hookworm gastrointestinal tract, especially that our analyses show expression of Ace-mep-7 in the adult stage of the parasite. Immunization of Syrian golden hamsters with Ace-mep-7 cDNA resulted in 50% (p < 0.01) intestinal worm burden reduction. Additionally 78% (p < 0.05) egg count reduction in both sexes was observed. These results suggest that immunization with Ace-mep-7 may contribute to reduction in egg count released into the environment during the A. ceylanicum infection. PMID:26795262
Larissa Margareta BĂTRÂNCEA
Full Text Available The paper reviews the models of tax compliance with an emphasis on economic and behavioral perspectives. Although the standard tax evasion model of Allingham and Sandmo and other similar economic models capture some important aspects of tax compliance (i.e., taxpayers’ response to increases in tax rate, audit probability, penalty rate they do not suffice the need for an accurate prediction of taxpayers’ behavior. The reason is that they do not offer a comprehensive perspective on the sociological and psychological factors which shape compliance (i.e., attitudes, beliefs, norms, perceptions, motivations. Therefore, the researchers have considered examining taxpayers’ inner motivations, beliefs, perceptions, attitudes in order to accurately predict taxpayers’ behavior. As a response to their quest, behavioral models of tax compliance have emerged. Among the sociological and psychological factors which shape tax compliance, the ‘slippery slope’ framework singles out trust in authorities and the perception of the power of authorities. The aim of the paper is to contribute to the understanding of the reasons for which there is a need for a tax compliance model which incorporates both economic and behavioral features and why governments and tax authorities should consider these models when designing fiscal policies.
Johnson Taiwo Olajide
Full Text Available Most of the developing and under-developed countries have been facing a lot of challenges on the issue of economic growth, despite the fact that they are endowed with both natural and human resources. This study examines the determinants of real per Capita GDP growth in Organization of the Petroleum Exporting Countries (OPEC using a panel of twelve countries for the period of 1986 and 2010.The pooled Ordinary Least Squares (OLS, Fixed Effect (FE and Random Effect (RE models were employed to assess the relationship between CGDP and other economic variables used. The result showed that price level of consumptions (pc and investment share (ci are the important factors of CGDP that contribute to the economic growth of OPEC countries. The result also established that exchange rate (Xrat, price of GDP (p, purchasing power parity (ppp and ci have a positive influence on CGDP. The test statistic revealed that Random Effects Model (REM estimator is more efficient than OLS and that there is no significance difference between Fixed Effects Model (FEM and REM estimators.
Full Text Available In the past years majority of EU members experienced the highest economic decline in their modern history, but impacts of the global financial crisis were not distributed homogeneously across the continent. The aim of the paper is to examine a cohesion of European Union (plus Norway and Iceland in terms of an economic development of its members from the 1st of January 2008 to the 31st of December 2012. For the study five economic indicators were selected: GDP growth, unemployment, inflation, labour productivity and government debt. Annual data from Eurostat databases were averaged over the whole period and then used as an input for a cluster analysis. It was found that EU countries were divided into six different clusters. The most populated cluster with 14 countries covered Central and West Europe and reflected relative homogeneity of this part of Europe. Countries of Southern Europe (Greece, Portugal and Spain shared their own cluster of the most affected countries by the recent crisis as well as the Baltics and the Balkans states in another cluster. On the other hand Slovakia and Poland, only two countries that escaped a recession, were classified in their own cluster of the most successful countries
Karaçay Çakmak Hatice
Full Text Available The aim of this article is to examine the capability approach of Amartya Sen and mainstream economic theory in terms of their epistemological, methodological and philosophical/cultural aspects. The reason for undertaking this analysis is the belief that Sen's capability approach, contrary to some economists' claim, is uncongenial to mainstream economic views on epistemology and methodology (not on ontologically. However, while some social scientists regard that Sen, on the whole, is a mainstream economist, his own approach strongly criticizes both the theory and practice of mainstream economics.
B. Tom (Beril)
textabstractThe beneficial effect of angiotensin-converting enzyme (ACE) inhibitors in hypertension and heart failure may relate, at least in part, to their capacity to interfere with bradykinin metabolism. In addition, recent studies have provided evidence for bradykinin-potentiating effects of ACE
Stéphane J. Baele
Full Text Available The 2000s have witnessed the arrival and growing popularity of randomized controlled experiments (RCTs in Development Economics. Whilst this new way of conducting research on development has unfolded important insights, the ethical challenge it provokes has not yet been systematically examined. The present article aims at filling this gap by providing the first ad hoc discussion of the moral issues that accompany the use of RCTs in Development Economics. Claiming that this new research agenda needs its own, specific set of ethical guidelines, we expose the six ethical problems that these experiments potentially provoke and that should therefore be carefully assessed by ethics committees before an RCT is launched and by scholarly journals before its results are published.
Dmitry V. Gorbachev
Full Text Available The article describes the systematic approach to developing a system of combined models of discrete processes. Mathematical basis for constructing a model of information Petri nets.
We consider an overlapping generations model with public education and social security where the overall size of these policies is determined in a repeated voting game. We investigate the interaction between the politically determined policies and economic development in a Markov perfect equilibrium. The following results are obtained. First, the level of human capital determines whether these policies are sustained in the Markov perfect equilibrium. Second, if the level of initial human ...
Collins, R. Lorraine; Vincent, Paula C.; Yu, Jihnhee; Liu, Liu; Epstein, Leonard H.
In the U.S., marijuana is the most commonly used illicit drug. Its prevalence is growing, particularly among young adults. Behavioral economic indices of the relative reinforcing efficacy (RRE) of substances have been used to examine the appeal of licit (e.g., alcohol) and illicit (e.g., heroin) drugs. The present study is the first to use an experimental, simulated purchasing task to examine the RRE of marijuana. Young-adult (M age = 21.64 years) recreational marijuana users (N = 59) complet...
Energy is fundamental to the economic development of a society. Ensuring energy security is critical to the security, sovereignty, and well-being of any country. However, there is no consensus on the definition of energy security. This book attempts to construct an appropriate definition for the concept of energy security. The evolution of energy security is traced at both the global level and in the Indian context. The book elaborates on the concept of energy security, highlights its linkages, enumerates India’s indigenous energy resources, examines the status of energy security in the country, and makes policy suggestions to ensure energy security in the country.
The aurthor discusses various approaches to the characterization of the category “distribution” as the set of factors of economic growth as a unified system that allows to structure the existing growth factors, determine their subordination and to identify the most significant causal phenomena and conditions of economic growth.
Full Text Available The aurthor discusses various approaches to the characterization of the category “distribution” as the set of factors of economic growth as a unified system that allows to structure the existing growth factors, determine their subordination and to identify the most significant causal phenomena and conditions of economic growth.
Mistry, Rashmita S.; Lowe, Edward D.; Benner, Aprile D.; Chien, Nina
The current study used a mixed-methods approach to examine how low-income mothers managed their household economies, their experiences of economic pressure, and the consequences for family and child functioning. Qualitative analyses (N = 32 families) revealed that experiences of economic pressure were associated with an inability to afford "both"…
Full Text Available To gain a greater understanding of the spatial spillover effect of greenhouse gas emissions and their influencing factors, this paper provides a spatial analysis of four gas pollutants (CO2 emissions, SO2 emissions, NOx emissions, and dust emissions. Focusing on China, the paper also explores whether the four gas pollutants are influenced by the emissions of neighboring regions and other possible sources. The paper uses a global spatial autocorrelation analysis, local spatial association analysis and spatial lag model for empirical work. The results suggest that CO2, SO2, and NOx emissions show significant positive results for both the spatial correlation and space cluster effect in provincial space distribution.CO2 and NOx emissions have a significant positive spillover effect, while the SO2 emissions’ spatial spillover effect is positive but not significant. Economic growth and urbanization are the key determinants of CO2, dust, and NOx emissions, while energy efficiency and industrialization do not appear to play a role. This raises questions about the method of examining the spatial relationship between gas pollution, economic growth and urbanization in the future.
The command-and-control system to air quality controls is a mixture of technology-forcing standards for existing sources and offset for new sources. More stringent controls are required to achieve the ambient air quality standards in non-attainment urban areas which have been conformed with burgeoning economic growth. Due to the economy of scale and locale of polluting sources, some sources can implement these controls in a more cost-effective manner than others. In order to minimize the control costs of regulated sources, trading of emissions has been stipulated and has occurred among power plants to curb acid rain at the national level. Southern California is currently embarking on the trading of oxides of nitrogen, reactive organic compounds, and oxides of sulfur among existing and new stationary sources. New economic opportunities for entrepreneurs with advances control technology will arise under emissions trading. Trading will also result in the redistribution of emissions geographically and across industries. Through the linkage of a linear-programming trading model, a regional econometric model, and an urban airshed model, the impact of trading on the Southern California economy can thus be examined. This paper describes a framework which can be used to compare and contrast RECLAIM with the command-and-control system; and discusses a few issues which may arise in a trading market and how these issues can be dealt with are also examined
Zuniga, Allison F.; Rasky, Daniel; Pittman, Robert B.; Zapata, Edgar; Lepsch, Roger
The NASA COTS (Commercial Orbital Transportation Services) Program was a very successful program that developed and demonstrated cost-effective development and acquisition of commercial cargo transportation services to the International Space Station (ISS). The COTS acquisition strategy utilized a newer model than normally accepted in traditional procurement practices. This new model used Space Act Agreements where NASA entered into partnerships with industry to jointly share cost, development and operational risks to demonstrate new capabilities for mutual benefit. This model proved to be very beneficial to both NASA and its industry partners as NASA saved significantly in development and operational costs while industry partners successfully expanded their market share of the global launch transportation business. The authors, who contributed to the development of the COTS model, would like to extend this model to a lunar commercial services program that will push development of technologies and capabilities that will serve a Mars architecture and lead to an economical and sustainable pathway to transporting humans to Mars. Over the past few decades, several architectures for the Moon and Mars have been proposed and studied but ultimately halted or not even started due to the projected costs significantly exceeding NASA's budgets. Therefore a new strategy is needed that will fit within NASA's projected budgets and takes advantage of the US commercial industry along with its creative and entrepreneurial attributes. The authors propose a new COTS-like program to enter into partnerships with industry to demonstrate cost-effective, cis-lunar commercial services, such as lunar transportation, lunar ISRU operations, and cis-lunar propellant depots that can enable an economical and sustainable Mars architecture. Similar to the original COTS program, the goals of the proposed program, being notionally referred to as Lunar Commercial Orbital Transfer Services (LCOTS
Full Text Available A different intermodal transportation model based on cost analysis considering technical, economical, and operational parameters is presented. The model consists of such intermodal modes as sea-road, sea-railway, road-railway, and multimode of sea-road-railway. A case study of cargo transportation has been carried out by using the suggested model. Then, the single road transportation mode has been compared to intermodal modes in terms of transportation costs. This comparison takes into account the external costs of intermodal transportation. The research reveals that, in the short distance transportation, single transportation modes always tend to be advantageous. As the transportation distance gets longer, intermodal transportation advantages begin to be effective on the costs. In addition, the proposed method in this study leads to determining the fleet size and capacity for transportation and the appropriate transportation mode.
Kagliwal, Lalit D; Survase, Shrikant A; Singhal, Rekha S; Granström, Tom
A process for the fermentative production of propionic acid from whole wheat flour using starch and gluten as nutrients is presented. Hydrolysis of wheat flour starch using amylases was optimized. A batch fermentation of hydrolysate supplemented with various nitrogen sources using Propionibacterium acidipropionici NRRL B 3569 was performed. The maximum production of 48.61, 9.40, and 11.06 g of propionic acid, acetic acid and succinic acid, respectively, was found with wheat flour hydrolysate equivalent to 90 g/l glucose and supplemented with 15 g/l yeast extract. Further, replacement of yeast extract with wheat gluten hydrolysate showed utilization of gluten hydrolysate without compromising the yields and also improving the economics of the process. The process so developed could be useful for production of animal feed from whole wheat with in situ production of preservatives, and also suggest utilization of sprouted or germinated wheat for the production of organic acids. PMID:23357590
Collins, R Lorraine; Vincent, Paula C; Yu, Jihnhee; Liu, Liu; Epstein, Leonard H
In the United States, marijuana is the most commonly used illicit drug. Its prevalence is growing, particularly among young adults. Behavioral economic indices of the relative reinforcing efficacy (RRE) of substances have been used to examine the appeal of licit (e.g., alcohol) and illicit (e.g., heroin) drugs. The present study is the first to use an experimental, simulated purchasing task to examine the RRE of marijuana. Young-adult (M age = 21.64 years) recreational marijuana users (N = 59) completed a computerized marijuana purchasing task designed to generate demand curves and the related RRE indices (e.g., intensity of demand-purchases at lowest price; Omax-max. spent on marijuana; Pmax-price at which marijuana expenditure is max). Participants "purchased" high-grade marijuana across 16 escalating prices that ranged from $0/free to $160/joint. They also provided 2 weeks of real-time, ecological momentary assessment reports on their marijuana use. The purchasing task generated multiple RRE indices. Consistent with research on other substances, the demand for marijuana was inelastic at lower prices but became elastic at higher prices, suggesting that increases in the price of marijuana could lessen its use. In regression analyses, the intensity of demand, Omax, and Pmax, and elasticity each accounted for significant variance in real-time marijuana use. These results provide support for the validity of a simulated marijuana purchasing task to examine marijuana's reinforcing efficacy. This study highlights the value of applying a behavioral economic framework to young-adult marijuana use and has implications for prevention, treatment, and policies to regulate marijuana use. PMID:24467370
This paper attempts to examine the dynamic relationship between economic growth, nuclear energy consumption, labor and capital for India for the period 1969-2006. Applying the bounds test approach to cointegration developed by we find that there was a short- and a long-run relationship between nuclear energy consumption and economic growth. Using four long-run estimators we also found that nuclear energy consumption has a positive and a statistically significant impact on India's economic growth. Further, applying the approach to Granger causality and the variance decomposition approach developed by , we found a positive and a significant uni-directional causality running from nuclear energy consumption to economic growth without feedback. This implies that economic growth in India is dependent on nuclear energy consumption where a decrease in nuclear energy consumption may lead to a decrease in real income. For a fast growing energy-dependent economy this may have far-reaching implications for economic growth. India's economic growth can be frustrated if energy conservation measures are undertaken without due regard to the negative impact they have on economic growth.
Marta Rey García; Luis Ignacio Álvarez González
Theoretical debate about the nature of charitable foundations has traditionally become polarized around two distinct conceptual approaches: the non-profit or third sector approach, versus the social economy approach. This research tries to find a common ground between these two approaches, and to highlight the specificities of the foundation as an organizational formula, supporting its current socio-economic relevance with latest quantitative data on the contemporary Spanish foundation sector...
This paper describes the principles, and suggests a methodology for expanding the dispatch of electrical power production systems for involving a pure minimum cost dispatch, to also include environmental objectives. The approach is qualitative in that no attempt is made as to assign a specific monetary value to environmental impacts, but rather maintaining the physical value of the impact through the decision process. However, the initial relative weights assigned to environmental impacts in the methodology are based on the many recent attempts to monetize environmental damages. The main contribution of the approach is to analyze how dispatch changes as a function of the total environmental weight, and as a function of the relative weighing of individual environmental insults, e.g., SO2, NOx and CO2. The methodology is illustrated with a sample production system involving environmental coast estimates from major US studies
Full Text Available Syncope is defined as a transient loss of consciousness due to sudden temporary decline in cerebral perfusion. Cough syncope is classically seen in middle aged obese men with obstructive pulmonary disease. In patients that use Angiotensin converting enzyme (ACE inhibitors, a dry persistent cough can emerge due to the side effects of this medication. Seventy years old male patient that use ACE inhibitor for hypertension accepted to the clinic with the complaint of syncope. A bout of coughing has developed during electroencephalography recording and 10 seconds in duration of subcortical like epileptiform discharges were viewed. The ACE inhibitor the patient was receiving was replaced with calcium channel blocker and no complaint was observed during the follow up period. [Cukurova Med J 2015; 40(3.000: 619-622
Full Text Available In the past, philosophy of education and curriculum designing focused on specialization and single disciplinarity approach .But since the turn of the 20th century, by a vast literature of realizing real and new educational needs and competencies beyond a single discipline, and criticizing the limits of that narrow approach to the reality, defining integrated curriculum or non-disciplinarity approaches has been a topic of discussion .Over the last decades, theorists offered six basic categories for non-disciplinary works :Parallel Disciplinary Approach, Interdisciplinary Approach, Multi-Disciplinary Approach, Cross-Disciplinary Approach, Plural-Disciplinary Approach and Supra/Trans-Disciplinary Approach. Through these approaches, integration seemed to be a matter of degree and method from fundamentally different starting points. Economics also is essentially an integrated discipline from different social sciences, mathematics, economic subjects, knowledge and ideas, and even methodology of natural sciences, and inevitably, its curriculum, educational programs and courses can not be designed unless benefited from these literature and approaches in the curriculum designing subject area. The present article briefly defines the non-disciplinarity approaches and shows their implications, applications and theoretical capacity in designing different possible curriculum and graduate educational courses in Economics.
The economic and schedule risks of Environmental Restoration (ER) projects are commonly analyzed toward the end of the baseline development process. Risk analysis is usually performed as the final element of the scheduling or estimating processes for the purpose of establishing cost and schedule contingency. However, there is an opportunity for earlier assessment of risks, during development of the technical scope and Work Breakdown Structure (WBS). Integrating the processes of risk management and baselining provides for early incorporation of feedback regarding schedule and cost risk into the proposed scope of work. Much of the information necessary to perform risk analysis becomes available during development of the technical baseline, as the scope of work and WBS are being defined. The analysis of risk can actually be initiated early on during development of the technical baseline and continue throughout development of the complete project baseline. Indeed, best business practices suggest that information crucial to the success of a project be analyzed and incorporated into project planning as soon as it is available and usable
Belokrylova Olga, S.
Full Text Available It is shown that the innovative activity of universities in Russia is always accompanied by the organizational changes carried out in the framework of the concept of stage-by-stage approach – a combination of natural and subjectively rational principle and based on intra-organizational integration of all subjects of University ethos for joint decisions in the field of organizational change. The authors analyze the mission transformation of universities determined by formation of information society which now is including not only development of the human capital, but also creation of knowledge as the competitive product possessing the essential production and social importance.
The EC/US study of the external costs of fuel cycles is designed to trace through all the environmental impacts arising from the use of a particular fuel, from the 'cradle' to the 'grave'; to quantify these impacts as far as possible (giving priority to those that are the considered the most important) and to value the damages arising from them in money terms as far as possible (again keeping to the priority listing established by the physical quantification). The fuel cycle has been identified as consisting of the following elements: activities -> emissions/burdens; emissions/burdens -> physical environmental impacts; physical impacts -> external environmental impacts; external impacts -> costs of these impacts. The activities consist of all the operations that are carried out in connection with the extraction transportation, use in electricity generation and finally disposal of the fuel. The emissions or burdens arising from the cycle result in physical impacts, which in turn imply certain environmental impacts. An illustration of a typical fuel cycle (coal) audits environmental impacts is given in Figures. The work of the fuels cycle study teams is to complete the valuation of the shaded areas but giving priority to those impacts that are likely to be quantitatively important. .Each fuel cycle is evaluated in a location-specific context, so that it refers to the impacts arising from the use of coal, or gas or whatever fuel is being considered at an actual plant that is operating. The purpose of this report on economic valuation is to: (a) examine the literature or economic valuation of environmental externalities in Europe; (b) assess its relevance to the fuel cycle study and (c) make recommendations on how the detailed analysis of the individual fuel cycles should use the economic valuation. It is important to recognize that the report is not a complete survey of all the research ever done on environmental valuation. Although as complete a survey of all the
Konno, C.; Ochiai, K.; Takakura, K.; Sato, S.
Some neutron KERMA factors in ACE files are negative and extremely large if nuclear data libraries do not keep energy-balance. The status of neutron KERMA factors in the official ACE file of ENDF/B-VII.1 is examined. As a result, it is found out that neutron KERMA factors of nuclei more than 200 in ENDF/B-VII.1 have some problems. Effects of the inadequate KERMA factor are also investigated, which are large for neutron heat while those are small for total (neutron + gamma) heat. Users who use only neutron KERMA factors should check if the factors are adequate or not before they use the factors.
Do, Truong Xuan; Lim, Young-Il; Jang, Sungsoo; Chung, Hwa-Jee
A hierarchical four-level approach to determine economic potential (4-level EP) is proposed for preliminary techno-economic analysis of new processes. The 4-level EP includes input/output structure, process flow structure, heat integration (HI), and economic feasibility. Two case studies on a 30.2 t/d (or 12.7 million l/yr) bioethanol plant with and without jet fuel production from palm empty fruit bunches (EFB) were investigated by applying the 4-level EP. The plant flowsheet was established based on experiments in a 0.1t/d pilot plant, including sequential dilute acid and alkali pretreatment, and separate hydrolysis and fermentation (SHF). EP approached a more reliable value through the hierarchical 4-level EP. The heating energy was reduced considerably by HI. The product value was estimated at $0.8-$1.3/kg of equivalent bioethanol. It was suggested through sensitivity analysis that a large plant size, enhanced production yields, and capital cost reduction were necessary for the lignocellulosic bioethanol production to be profitable. PMID:25898083
The options available to Energy Service Companies when improving the energy performance of an existing building are often driven by short-term payback cycles. The value of a measure is based on how quickly it pays for itself. The more quickly the energy savings created by the measure exceed the cost of purchasing and installing the measure, the more comfortable the engineer feels recommending that improvement. In the best cases, the short-term approach will quickly retire the debts associated with a particular retrofit and provide a dependable, albeit limited net savings stream for the property owner. The engineer has obtained energy savings for his client. The problem with this short-term approach is that it automatically eliminates other conservation measures which, over longer time horizons, could add far more value for the customer. The installation of new, extremely energy efficient replacement windows is a case in point. During preliminary discussions with our clients, (typically Public Housing Authorities or owners of subsidized, multi-family housing), the conversation eventually turns to the issue of replacement windows. The perception is that new windows are a luxury. The decision to install new windows is driven by maintenance costs and, in some cases, resident complaints over operability or draftiness associated with the existing windows. Typically the windows are not handled as part of the mainstream energy conservation program. If the client has already installed new windows, he probably based his selection on the low bidder of a unit that has marginal thermal performance. Every property has a budget and compromises must often be made to meet budgets. The purchaser may have not gotten the Cadillac of windows, but at least he got a good deal on the window that he did buy. His maintenance problems have been solved for the near term and resident complaints have gone down, for now
Full Text Available This paper addresses a special zone design problem for economic census investigators that is motivated by a real-world application. This paper presented a heuristic multikernel growth approach via Constrained Delaunay Triangulation (CDT. This approach not only solved the barriers problem but also dealt with the polygon data in zoning procedure. In addition, it uses a new heuristic method to speed up the zoning process greatly on the premise of the required quality of zoning. At last, two special instances for economic census were performed, highlighting the performance of this approach.
Lasaitiene, Daina; Chen, Yun; Nannmark, Ulf; Wollmer, Per; Friberg, Peter
The renin-angiotensin system (RAS) is developmentally up-regulated and it is essential for kidney development in several species. Given the fact that the rat lung undergoes postnatal development, the mammalian lung possesses the highest angiotensin-converting enzyme (ACE) levels and ACE activity increases during the first weeks postpartum, we tested the hypothesis that ACE inhibition influences postnatal lung development. Rats were given the ACE inhibitor enalapril (10 mg kg-1) from 0 to 9 da...
Starting in 1991, the French and German cooperation led to common work based on the experience of the two designers FRAMATOME and SIEMENS KWU with all their know how, the most important utilities in France and Germany operating NPP and the technical supports of the Licensing Authorities GRS and IPSN. The conclusion of that work was the issue in November 1997 and February 1999 respectively of two Basic Design reports for a European Pressurized Reactor (EPR) with a power of 4250 MWth and 4900 MWth. The Basic Design approach was led under two key items: Enhancement of the overall safety level by implementation of design measures to: make the plant less dependant to common cause failures; practically eliminate all high pressure core melt sequences which could lead to important radioactive releases to the environment; implement specific systems to face severe accident situation with low-pressure core melt. Use of the many years of experiences in two different nuclear designs is to reach an overall availability figure over 91%, partly due to design improvements on the safety level. With such an objective, demonstrated by feedback of experience on already operating plants, the EPR project can be proposed as a competitive alternative to the most recent fossil plants. (author)
Cutler, David M; Jessup, Amber I; Kenkel, Donald S; Starr, Martha A
The question of how to evaluate lost consumer surplus in benefit-cost analyses has been contentious. There are clear health benefits of regulations that curb consumption of goods with health risks, such as tobacco products and foods high in fats, calories, sugar, and sodium. Yet, if regulations cause consumers to give up goods they like, the health benefits they experience may be offset by some utility loss, which benefit-cost analyses of regulations need to take into account. This paper lays out the complications of measuring benefits of regulations aiming to curb consumption of addictive and habitual goods, rooted in the fact that consumers' observed demand for such goods may not be in line with their true preferences. Focusing on the important case of tobacco products, the paper describes four possible approaches for estimating benefits when consumers' preferences may not be aligned with their behavior, and identifies one as having the best feasibility for use in applied benefit-cost analyses in the near term. PMID:27102854
B. Tom (Beril); R. de Vries (René); P.R. Saxena (Pramod Ranjan); A.H.J. Danser (Jan)
textabstractACE inhibitors block B(2) receptor desensitization, thereby potentiating bradykinin beyond blocking its hydrolysis. Angiotensin (Ang)-(1-7) also acts as an ACE inhibitor and, in addition, may stimulate bradykinin release via angiotensin II type 2 receptors.
"This paper proposes a socio-psychological approach for empirical research into the influence of civil society contexts on the practices of individual economic actors. This methodological approach is based on social theories that explicitly take into account the link between structure and agency, and the paper explains how such framework can be utilised in qualitative interview-based studies. To illustrate the usefulness of such socio-psychological approach, the paper reports on the findings ...
This paper presents the design overview and approach to addressing the aforementioned economic challenges for two Advanced BWR designs. The first plant is the ABWR and the second is the ESBWR. The ABWR relies on proven technology and components and an extensive infrastructure that has been built up over the last 20 years. Because it has proven and standards safety systems it has very limited uncertainty regarding licensing. Finally, it relies on the economies of scale and overall design flexibility to improve the overall economics of power generation. The ESBWR on the other hand has taken an innovative approach to reduce systems and components to simplify the overall plant to improve plant economics. The overall plant design is indeed simpler, but improved economics required reliance on some economies of scale also. This design embodied in the ESBWR, also has minimized the overall development cost by utilizing features and components from the ABWR and SBWR technology programs
Zhukov Andrii V.
Full Text Available The article offers developments of a methodical approach to diagnostics of efficiency of production economic activity of an enterprise, which, unlike the existing ones, is realised through the following stages: analysis of the enterprise external environment; analysis of the enterprise internal environment; identification of components of efficiency of production economic activity for carrying out complex diagnostics by the following directions: efficiency of subsystems of the enterprise production economic activity, efficiency of use of separate types of resources and socio-economic efficiency; scorecard formation; study of tendencies of change of indicators; identification of cause-effect dependencies between the main components of efficiency for diagnosing reasons of its level; diagnosing deviations of indicator values from their optimal values; development of a managerial decision on preserving and increasing efficiency of production economic activity of the enterprise.
Eu.V. Mishenin; I.I. Koblianska
The aim of the article. The article highlights the lack of effectiveness of existing system of education management in Ukraine from its basic function performance – to satisfy the needs of social and economic system of human resources, according to the required quantity, quality, educational culture, right place and time with the lowest public costs. The results of the analysis. The article is focused on the forming of organizational and economic bases of the use of logistic approach in th...
The self-employment rate includes entrepreneurs out of opportunity and entrepreneurs out of necessity. While the effect of opportunity entrepreneurs on economic development should be positive, there should be no or a negative effect of necessity entrepreneurship. We use a geographically weighted regression (GWR) approach to analyze whether the effect of self-employment on economic development is heterogeneous across European NUTS-2 regions. We find that regions having a significant positive e...
Hoikkanen, Anssi; Bacigalupo, Margherita; Lusoli, Wainer; Maghiros, Ioannis; Nikolov, Stavri
This paper discusses the economics of electronic identity (eIdentity) from both theoretical and practical perspectives. Personal identity data are becoming increasingly important in online transactions, and they have never been monetised to the extent they are today. Consequently, there is a need for an improved understanding of the economic externalities resulting from the electronic use of identities in transactions. In this context, we distinguish four main theoretical approaches for under...
Full Text Available Problem Statement : Previous studies have associated angiotensin-converting enzyme (ACE with variability inthe skeletal muscle baseline strength, though conclusions have been inconsistent across investigations.Approach: The purpose of this study was to review the most important studies that have been exanimate thepossible association between ACE genotype and skeletal muscle baseline strength in elite male and femaleathletes involved in elderly populations. This research is needed because the possibility that the DD genotypemay be associated with a greater proportion of fast twitch fibers could explain the influence of the ACE D alleleupon strength/ power, particularly at high velocities, but this evidence remains equivocal in older people becausemore studies are necessary.Results: Thus, according to scientific evidence, changes in muscle strength with exercise training in olderindividuals may be dependent on ACE I/D genotype. Of note, the results provide a novel insight that thesegenetic variations may interact to determine muscle mass in older women specially. The determination of thispredisposition in this population, highlighting the interest of study, for the prophylactic attitude on the factorsand causes of aging (sarcopenia, osteoporosis, risk of falls, reduction of functional physical go through thisanalysis.Conclusions/Recommendations: In this work, the state of the art related to the influence of the ACE genotypeon skeletal muscle strength was presented and some important relations were reported
Niyato, D.; Lu, X.; Wang, P.; Kim, D I; Han, Z.
Internet of things (IoT) has been proposed to be a new paradigm of connecting devices and providing services to various applications, e.g., transportation, energy, smart city, and healthcare. In this paper, we focus on an important issue, i.e., economics of IoT, that can have a great impact to the success of IoT applications. In particular, we adopt and present the information economics approach with its applications in IoT. We first review existing economic models developed for IoT services....
Full Text Available Thorstein Veblen, a founder of original or old institutional economics, combined social and evolutionary thought in his institutionalist approach to dealing with psychological, social, and economic issues. The psychological content of Veblen's writings takes instinct and habits into consideration. The economic literature on the psychological content of Veblen's writings has focused on habits, despite the importance of instincts in Veblen's works. This paper attempts to discuss Veblen's notion of instincts in order to make its role clearer in his approach to conspicuous consumer decision making. It discusses the role of instincts, the instinct of workmanship, the relationship between habits and instincts, and their influence on the conspicuous consumer. Consequently, this paper contributes to a better understanding of how inner forces and socialization culminate in behavior in Veblen's conspicuous consumer approach.
Full Text Available John Dewey is one of the most significant figures in pragmatist philosophy, an approach which he systematically applied to the study of economic, social and cultural structure. In our work, we will focus on the main aspects of Dewey’s approach to the study of aspects that make up “human nature” and how do they interact with the characteristics of the cultural context. We will illustrate how the concepts elaborated by Dewey can contribute to the heterodox analysis of a host of economic and social issues. Dewey highlights the crucial role of public policies for facilitating the development of volunteer associations in all areas of the social structure. In the analysis of these aspects, Dewey’s key contribution lies in removing the concepts of democracy and participation from the limbo of abstraction in which they tended to be confined by previous approaches and connecting them to the evolution of economic and social forms.
Falkenberg, Susan Skanderup; Stagsted, Jan; Nielsen, Henrik Hauch
secondary marine products. The approach in this study is to hydrolyse skin and belly flap tissue from Salmon with the use of mammalian digestive proteases from pancreas and intestinal mucosa and test hydrolysates for antioxidative capacity, intestinal DPP-IV and angiotensin converting enzyme (ACE...... amino groups, antioxidative capacity by ABTS (2,2-azinobis(3-ethylbenzothiazoline-6-sulfonicacid)), DPP-IV and ACE inhibiting activity. Degree of hydrolysis (DH) of hydrolysates was approximately 13% and 10% for belly flap and skin respectively. No clear difference was observed in DH between pancreatin...... and pancreatin + mucosa hydrolysates. No DH was obtained for tissues hydrolysed with only intestinal mucosa extract. Preliminary results showed antioxidant activity and intestinal DPP-IV and ACE inhibiting activity in 10 kDa fraction from both belly flap and skin hydrolysates but with a higher...
Modern society is characterised not only by a fascination with scientific technology as a means of solving all problems, especially those that stand in the way of material progress (technicism), but also by an obsessive interest in everything that has to do with money (economism or mammonism). The article discusses the relationship between technicism and economism, on the basis of their relationship to utilitarian thinking: the quest for the greatest happiness for the greatest number of peopl...
AceWiki is a prototype that shows how a semantic wiki using controlled natural language - Attempto Controlled English (ACE) in our case - can make ontology management easy for everybody. Sentences in ACE can automatically be translated into first-order logic, OWL, or SWRL. AceWiki integrates the OWL reasoner Pellet and ensures that the ontology is always consistent. Previous results have shown that people with no background in logic are able to add formal knowledge to AceWiki without being in...
AceWiki is a prototype that shows how a semantic wiki using controlled natural language - Attempto Controlled English (ACE) in our case - can make ontology management easy for everybody. Sentences in ACE can automatically be translated into first-order logic, OWL, or SWRL. AceWiki integrates the OWL reasoner Pellet and ensures that the ontology is always consistent. Previous results have shown that people with no background in logic are able to add formal knowledge to AceWiki without being instructed or trained in advance.
Economic valuation of environmental attributes are pragmatic approach to evaluating the impacts and it helps decision makers to arrive at objective decisions on the basis of cost benefit ratio. For determining the physical impact and its quantification, four evaluation methods, namely-market price method, surrogate market price, survey based and cost based approaches are generally used. The present paper reviews the importance of environmental evaluation of impacts of mining and also reviews a few suitable methodologies that could be effectively used for economic evaluation of environmental impacts in open cast mining projects. (author)
Sustainable Development Commission
As part of the Trust's approach to good corporate citizenship, the Actions for Community Employment (ACE) project provides increased employment opportunities for local residents, generating a more representative workforce across the Trust's three teaching hospitals and contributing to sustainable regeneration in one of the most disadvantaged areas of Britain. Publisher PDF
Sprigg, James A.; Pryor, Richard J.; Jorgensen, Craig Reed
We are extending the existing features of Aspen, a powerful economic modeling tool, and introducing new features to simulate the role of confidence in economic activity. The new model is built from a collection of autonomous agents that represent households, firms, and other relevant entities like financial exchanges and governmental authorities. We simultaneously model several interrelated markets, including those for labor, products, stocks, and bonds. We also model economic tradeoffs, such as decisions of households and firms regarding spending, savings, and investment. In this paper, we review some of the basic principles and model components and describe our approach and development strategy for emulating consumer, investor, and business confidence. The model of confidence is explored within the context of economic disruptions, such as those resulting from disasters or terrorist events.
Journal rankings based on citation indexes are widely used in the economics field for global top journals. We propose an alternative way to rank journals based on the publishing behavior of top ranked authors. We justify this approach by depicting the scientific publishing market as following a matching process. Compared to the citation approach, the methodology that we propose has comparative advantages in terms of time effort to produce national and subdiscipline rankings, and it makes it p...
Sandal, Leif Kristoffer; Berge, Gerhard
Dynamic optimization problems covers a great class of problems in management science and technology. The classical problem formulations being the variational approach as in classical mechanics, like Hamilton's principle and the optimal control theory in economics as the Pontryagin's maximum principle. In this account we start with a general problem formulation as an alternative to an approach based on solving differential equations. We focus on creating an analytical environment aimed at deri...
Dewachter, Hans; Lyrio, M.
We adapt Brandt's (1999) nonparametric approach to determine the optimal portfolio choice of a risk averse foreign exchange investor who uses moving average trading signals as the information instrument for investment opportunities. Additionally, we assess the economic value of the estimated optimal trading rules based on the investor's preferences. The approach consists of a conditional generalized method of moments (GMM) applied to the conditional Euler optimality conditions. The method pre...
Hans Dewachter; Marco Lyrio
We adapt Brandt's (1999) nonparametric approach to determine the optimal portfolio choice of a risk averse foreign exchange investor who uses moving average trading signals as the information instrument for investment opportunities. Additionally, we assess the economic value of the estimated optimal trading rules based on the investor's preferences. The approach consists of a conditional generalized method of moments (GMM) applied to the conditional Euler optimality conditions. The method pre...
Matyushenko Olga I.
Full Text Available The article identifies urgency of the enterprise life cycle theory in the system of managing financial and economic activity of an enterprise, identifies problems and insufficiently developed theoretical issues, namely, identification of the main indicator of the state of an organisation on the life cycle curve, which thoroughly characterises its financial and economic activity. It develops and offers a methodical approach to identification of the financial and economic state of an enterprise. The article analyses, generalises and identifies main sub-systems of an enterprise within the proposed methods. On the basis of analysis of works of scientists the article identifies main indicators that characterise each subsystem of an enterprise and identifies the entropy method, having analysed the existing methods of calculation of an integral indicator, as the most justified approach to calculation of the enterprise life cycle integral indicator.
Full Text Available Central Bank of Indonesia with dual banking system – i.e Shariah and Conventional Bank – keep on developing system that considered as an answer to generate the national economic growth. One of the banking activities that emphasized by the Central Bank of Indonesia is fund distribution through either conventional bank credit or shariah bank fi nancing. Having the Experimental Economic Approach based on Induced Value Theory and employing ANOVA, this paper found that shariah bank musharakah fi nancing system would come up with higher profi t opportunity compare to conventional credit system. One main reason is that musharakah fi nancing in shariah bank applies profi t and lost sharing (PLS scheme so that will not be a burden to the customer when he fi nd low profi t.Keywords: Credit Loan, Musharakah Financing, Induced Value Theory, Experimental Economic Approach, Analysis of Variance (ANOVA.
Full Text Available This article tries to show that there are alternative approaches to the economic theory, besides the well-known economic schools, Classicism, Neoclassicism and Keynesianism. The neoclassical principles allow a formalization – widely accepted by experts – that provide effective tools for measuring the effects of the economic activity. The economic science pays a special attention to the study of the economic agents’ behaviors, and to the economic results obtained by them through economic activity. Any human science uses principles and works with assumptions, and the neoclassical assumptions have generated efficient tools for quantifying the economic outcomes, and for accounting the economic growth. But these hypothesis, such as the assumption of economic agents’ rationality, allow a very limited understanding of the behaviors of economic agents within the markets. The recent invention of the Nuclear Magnetic Resonance device, allowed the emrgence of a new scientific paradigm, the development of neurosciences. Researchers can observe at a high level of graphic detail various types of activities that occur in the human brain, and some economists have introduced in the study of the economic theory, for example, the assumption that the consumer is driven by emotions when purchasing quantities of goods and services. So, economists may look for additional theories to explain the behavior of the economic agents. An increasingly importance is given to the theoretical contributions built on the work of the economist Joseph Alois Schumpeter, who has an original economic approach based on his own principles. It is proposed to focus the attention on a mesoeconomic vision about the industry, to understand how resources are being allocated and reallocated between companies, and to study the economic processes of evolution, which are influenced by the emergence and dissemination of the innovations. It is supposed that the price is allocating the
King, Dominic; Greaves, Felix; Vlaev, Ivo; Darzi, Ara
Policies that change the environment or context in which decisions are made and "nudge" people toward particular choices have been relatively ignored in health care. This article examines the role that approaches based on behavioral economics could play in "nudging" providers and patients in ways that could slow health care spending growth. The basic insight of behavioral economics is that behavior is guided by the very fallible human brain and greatly influenced by the environment or context in which choices are made. In policy arenas such as pensions and personal savings, approaches based on behavioral economics have provided notable results. In health care, such approaches have been used successfully but in limited ways, as in the use of surgical checklists that have increased patient safety and reduced costs. With health care spending climbing at unsustainable rates, we review the role that approaches based on behavioral economics could play in offering policy makers a potential set of new tools to slow spending growth. PMID:23569045
Flégl, Martin; Vltavská, Kristýna
The paper evaluates research and teaching efficiency at faculties of economics in the public higher education institutions in the Czech Republic. Evaluation is provided in two periods between the years 2006-2010 and 2007-2011. For this evaluation the Data Envelopment Analysis and Index approach are used. Data Envelopment Analysis measures research…
David S Cobden
Full Text Available David S Cobden1, Louis W Niessen2, Frans FH Rutten1, W Ken Redekop11Department of Health Policy and Management, Section of Health Economics – Medical Technology Assessment (HE-MTA, Erasmus MC, Erasmus University Rotterdam, The Netherlands; 2Department of International Health, Johns Hopkins University School of Public Health, Johns Hopkins Medical Institutions, Baltimore, MD, USAAims: While strong correlations exist between medication adherence and health economic outcomes in type 2 diabetes, current economic analyses do not adequately consider them. We propose a new approach to incorporate adherence in cost-effectiveness analysis.Methods: We describe a theoretical approach to incorporating the effect of adherence when estimating the long-term costs and effectiveness of an antidiabetic medication. This approach was applied in a Markov model which includes common diabetic health states. We compared two treatments using hypothetical patient cohorts: injectable insulin (IDM and oral (OAD medications. Two analyses were performed, one which ignored adherence (analysis 1 and one which incorporated it (analysis 2. Results from the two analyses were then compared to explore the extent to which adherence may impact incremental cost-effectiveness ratios.Results: In both analyses, IDM was more costly and more effective than OAD. When adherence was ignored, IDM generated an incremental cost-effectiveness of $12,097 per quality-adjusted life-year (QALY gained versus OAD. Incorporation of adherence resulted in a slightly higher ratio ($16,241/QALY. This increase was primarily due to better adherence with OAD than with IDM, and the higher direct medical costs for IDM.Conclusions: Incorporating medication adherence into economic analyses can meaningfully influence the estimated cost-effectiveness of type 2 diabetes treatments, and should therefore be considered in health care decision-making. Future work on the impact of adherence on health economic
Lybbert, Travis J.; Nikolas J. Zolas
International technological diffusion is a key determinant of cross-country differences in economic performance. While patents can be a useful proxy for innovation and technological change and diffusion, fully exploiting patent data for such economic analyses requires patents to be tied to measures of economic activity. In this paper, we describe and explore a new algorithmic approach to constructing concordances between the International Patent Classification (IPC) system that organizes pate...
The aim of this paper is to re-examine the relationship between electricity consumption, economic growth, and employment in Portugal using the cointegration and Granger causality frameworks. This study covers the sample period from 1971 to 2009. We examine the presence of a long-run equilibrium relationship using the bounds testing approach to cointegration within the Unrestricted Error-Correction Model (UECM). Moreover, we examine the direction of causality between electricity consumption, economic growth, and employment in Portugal using the Granger causality test within the Vector Error-Correction Model (VECM). As a summary of the empirical findings, we find that electricity consumption, economic growth, and employment in Portugal are cointegrated and there is bi-directional Granger causality between the three variables in the long-run. With the exception of the Granger causality between electricity consumption and economic growth, the rest of the variables are also bi-directional Granger causality in the short-run. Furthermore, we find that there is unidirectional Granger causality running from economic growth to electricity consumption, but no evidence of reversal causality. - Highlights: → We re-examine the relationship between electricity consumption, economic growth, and employment in Portugal. → The electricity consumption and economic growth is causing each other in the long-run. → In the short-run, economic growth Granger-cause electricity consumption, but no evidence of reversal causality. → Energy conservation policy will deteriorate the process of economic growth in the long-run. → Portugal should increase investment on R and D to design new energy savings technology.
Kim, Hakkwan; Parajuli, Prem B.; Yu, Fei; Columbus, Eugene P.
Economic analysis and modeling are essential and important issues for the development of current feedstock and process technology for bio-gasification. The objective of this study was to develop an economic model and apply to predict the unit cost of syngas production from a micro-scale bio-gasification facility. An economic model was programmed in C++ computer programming language and developed using a parametric cost approach, which included processes to calculate the total capital costs and the total operating costs. The model used measured economic data from the bio-gasification facility at Mississippi State University. The modeling results showed that the unit cost of syngas production was $1.217 for a 60 Nm-3 h-1 capacity bio-gasifier. The operating cost was the major part of the total production cost. The equipment purchase cost and the labor cost were the largest part of the total capital cost and the total operating cost, respectively. Sensitivity analysis indicated that labor costs rank the top as followed by equipment cost, loan life, feedstock cost, interest rate, utility cost, and waste treatment cost. The unit cost of syngas production increased with the increase of all parameters with exception of loan life. The annual cost regarding equipment, labor, feedstock, waste treatment, and utility cost showed a linear relationship with percent changes, while loan life and annual interest rate showed a non-linear relationship. This study provides the useful information for economic analysis and assessment of the syngas production using a modeling approach.
Odhiambo, Nicholas M. [Economics Department, University of South Africa (UNISA), P.O. Box 392, UNISA, 0003, Pretoria (South Africa)], E-mail: firstname.lastname@example.org
In this paper, we examine the intertemporal causal relationship between energy consumption and economic growth in Tanzania during the period of 1971-2006. Unlike the majority of the previous studies, we employ the newly developed autoregressive distributed lag (ARDL)-bounds testing approach by Pesaran et al. [2001. Bounds testing approaches to the analysis of level relationships. Journal of Applied Econometrics 16, 289-326] to examine this linkage. We also use two proxies of energy consumption, namely total energy consumption per capita and electricity consumption per capita. The results of the bounds test show that there is a stable long-run relationship between each of the proxies of energy consumption and economic growth. The results of the causality test, on the other hand, show that there is a unidirectional causal flow from total energy consumption to economic growth and a prima-facie causal flow from electricity consumption to economic growth. Overall, the study finds that energy consumption spurs economic growth in Tanzania.
In this paper, we examine the intertemporal causal relationship between energy consumption and economic growth in Tanzania during the period of 1971-2006. Unlike the majority of the previous studies, we employ the newly developed autoregressive distributed lag (ARDL)-bounds testing approach by Pesaran et al. [2001. Bounds testing approaches to the analysis of level relationships. Journal of Applied Econometrics 16, 289-326] to examine this linkage. We also use two proxies of energy consumption, namely total energy consumption per capita and electricity consumption per capita. The results of the bounds test show that there is a stable long-run relationship between each of the proxies of energy consumption and economic growth. The results of the causality test, on the other hand, show that there is a unidirectional causal flow from total energy consumption to economic growth and a prima-facie causal flow from electricity consumption to economic growth. Overall, the study finds that energy consumption spurs economic growth in Tanzania
Odhiambo, Nicholas M. [Economics Department, University of South Africa (UNISA), P.O. Box 392, UNISA, 0003, Pretoria (South Africa)
In this paper, we examine the intertemporal causal relationship between energy consumption and economic growth in Tanzania during the period of 1971-2006. Unlike the majority of the previous studies, we employ the newly developed autoregressive distributed lag (ARDL)-bounds testing approach by Pesaran et al. [2001. Bounds testing approaches to the analysis of level relationships. Journal of Applied Econometrics 16, 289-326] to examine this linkage. We also use two proxies of energy consumption, namely total energy consumption per capita and electricity consumption per capita. The results of the bounds test show that there is a stable long-run relationship between each of the proxies of energy consumption and economic growth. The results of the causality test, on the other hand, show that there is a unidirectional causal flow from total energy consumption to economic growth and a prima-facie causal flow from electricity consumption to economic growth. Overall, the study finds that energy consumption spurs economic growth in Tanzania. (author)
Availability of and access to useful energy is a crucial factor for maintaining and improving human well-being. Looming scarcities and increasing awareness of environmental, economic, and social impacts of conventional sources of non-renewable energy have focused attention on renewable energy sources, including biomass. The complex interactions of social, economic, and ecological factors among the bioenergy system components of feedstock supply, conversion technology, and energy allocation have been a major obstacle to the broader development of bioenergy systems. For widespread implementation of bioenergy to occur there is a need for an integrated approach to model the social, economic, and ecological interactions associated with bioenergy. Such models can serve as a planning and evaluation tool to help decide when, where, and how bioenergy systems can contribute to development. One approach to integrated modeling is by assessing the sustainability of a bioenergy system. The evolving nature of sustainability can be described by an adaptive systems approach using general systems principles. Discussing these principles reveals that participation of stakeholders in all components of a bioenergy system is a crucial factor for sustainability. Multi-criteria analysis (MCA) is an effective tool to implement this approach. This approach would enable decision-makers to evaluate bioenergy systems for sustainability in a participatory, transparent, timely, and informed manner
Highlights: • Exploitation of medium to low temperature geothermal sources: ORC power plants. • Integrated energetic and economic approach for the analysis of geothermal power plants. • A brief overview of the cost items of geothermal power plants. • Analysis of specific cost of geothermal power plants based on the method proposed. • Analysis of sustainability of geothermal energy systems based on resource durability. - Abstract: The perspectives of future development of geothermal power plants, mainly of small size for the exploitation of medium–low temperature reservoirs, are discussed and analyzed in the present paper. Even if there is a general interest in new power plants and investments in this sector are recognized, the new installations are reduced; the apparent advantage of null cost of the energy source is negatively balanced by the high drilling and installation costs. A key element for the design of a geothermal plant for medium temperature geothermal source is the definition of the power of the plant (size): this is important in order to define not only the economic plan but also the durability of the reservoir. Considering that it is not possible that the development of geothermal industry could be driven only by an economic perspective, the authors propose a method for joining energetic and economic approaches. The result of the combined energetic and economic analysis is interesting particularly in case of Organic Rankine Cycle (ORC) power plants in order to define a suitable and optimal size and to maximize the resource durability. The method is illustrated with reference to some particular case studies, showing that the sustainability of small size geothermal plants will be approached only if the research for more economic solutions will be combined with efforts in direction of efficiency increase
Full Text Available In this paper, we investigate the impact of tax composition on economic growth, based on a panel-model approach. The dataset includes six East-European countries and covers the period 1995-2012. Specifically, the study explores the relative impact of different components of tax revenue (direct and indirect tax revenue, as percentage of total tax revenue on economic growth. The paper adds marginally to the empirical literature, showing how the two types of tax revenue influence economic growth in Eastern Europe, under an extended set of economic and sociopolitical control variables. The most important empirical output, for the 6 investigated East-European countries during 1995-2012, suggests that direct taxes are significant and negatively correlated with economic growth, while indirect taxes exert a positive influence on the dependent variable, though insignificant. As for the control variables, it seems that only freedom from corruption and political stability have a significant impact on economic growth. The study suggests that the design of tax systems in Eastern European countries is in accordance with the Commission’s priorities regarding its growth-friendliness. As for policy implications, governments should continue shifting the tax burden away from labour on to tax bases linked to consumption, property, and combating pollution, with potential positive effects both for growth and for fighting against tax evasion.
The study probes cointegration and causality between carbon emissions and economic growth for India using ARDL bounds testing approach complemented by Johansen-Juselius maximum likelihood procedure in a multivariate framework by incorporating energy supply, investment and employment for time span 1971-2006. The study fails to establish long-run equilibrium relationship and long term causality between carbon emissions and economic growth; however, there exists a bi-directional short-run causality between the two. Hence, in the short-run, any effort to reduce carbon emissions could lead to a fall in the national income. This study also establishes unidirectional short-run causality running from economic growth to energy supply and energy supply to carbon emissions. The absence of causality running from energy supply to economic growth implies that in India, energy conservation and energy efficiency measures can be implemented to minimize the wastage of energy across value chain. Such measures would narrow energy demand-supply gap. Absence of long-run causality between carbon emissions and economic growth implies that in the long-run, focus should be given on harnessing energy from clean sources to curb carbon emissions, which would not affect the country's economic growth.
Full Text Available This paper describes new approaches to social and economic research being developed by the Social and Economic Research component of the Special Programme for Research and Trainning in Tropical Diseases of the World Health Organization. One of these is a study to acess the possibility of identifying high risk communities for urinary schistosomiasis through a "mailed"questionaire approach distributed through an existing administrative system, thereby eliminating the need for face-to-face interviews by the research or disease control team. This approach, developed by the Swiss Tropical Institute in Ifakara, Tanzania, i s currently being tested in seven other African countries. The paper also describes a change of emphasis of economic research on schistosomiasis, focusing on the intra-household effects of the disease on rural households, rather than, as previously done, studying the impact of the disease on the productivity of individual wage labourers. Other priorities involve the identification of epidemiological information neede for improoved decision-making regarding acceptable treatment strategies in endemic areas with limited financial capacity, as well as research on how the adverse effects of economic development projects can be alleviated.
Lefever, Els; Hoste, Veronique
Breaking news on economic events such as stock splits or mergers and acquisitions has been shown to have a substantial impact on the financial markets. As it is important to be able to automatically identify events in news items accurately and in a timely manner, we present in this paper proof-of-concept experiments for a supervised machine learning approach to economic event detection in newswire text. For this purpose, we created a corpus of Dutch financial news articles in which 10 types o...
New Approaches to the Design and Economics of EHV Transmission Plant examines the limitations of EHV transmission plant. Analysis is also covered in the book to correct these limitations. The concept behind EHV is that allowable transfer of electricity is related to the square of the voltage. Factors such as the expense of supplying a certain volume of electricity over a given distance and creations of power stations are examined. The book provides economic studies of alternative design policies based on estimation of costs and benefits of the design parameters. The text also focuses on the pr
ED (Economic Dispatch) is non-convex constrained optimization problem, and is used for both on line and offline studies in power system operation. Conventionally, it is solved as convex problem using optimization techniques by approximating generator input/output characteristic. Curves of monotonically increasing nature thus resulting in an inaccurate dispatch. The GA (Genetic Algorithm) has been used for the solution of this problem owing to its inherent ability to address the convex and non-convex problems equally. This approach brings the solution to the global minimum region of search space in a short time and then takes longer time to converge to near optimal results. GA based hybrid approaches are used to fine tune the near optimal results produced by GA. This paper proposes NGH (Neuro Genetic Hybrid) approach to solve the economic dispatch with valve point effect. The proposed approach combines the GA with the ANN (Artificial Neural Network) using SI (Swarm Intelligence) learning rule. The GA acts as a global optimizer and the neural network fine tunes the GA results to the desired targets. Three machines standard test system has been tested for validation of the approach. Comparing the results with GA and NGH model based on back-propagation learning, the proposed approach gives contrast improvements showing the promise of the approach. (author)
Nakaten, Natalie; Kempka, Thomas; Burchart-Korol, Dorota; Krawczyk, Piotr; Kapusta, Krzysztof; Stańczyk, Krzysztof
Underground coal gasification (UCG) enables the utilization of coal reserves that are economically not exploitable because of complex geological boundary conditions. In the present study we investigate UCG as a potential economic approach for conversion of deep-seated coals into a synthesis gas and its application within three different utilization options. Related to geological boundary conditions and the chosen gasification agent, UCG synthesis gas composes of varying methane, hydrogen, nitrogen, carbon monoxide and carbon dioxide amounts. In accordance to its calorific value, the processed UCG synthesis gas can be utilized in different manners, as for electricity generation in a combined cycle power plant or for feedstock production making use of its various chemical components. In the present study we analyze UCG synthesis gas utilization economics in the context of clean electricity generation with an integrated carbon capture and storage process (CCS) as well as synthetic fuel and fertilizer production (Kempka et al., 2010) based on a gas composition achieved during an in situ UCG trial in the Wieczorek Mine. Hereby, we also consider chemical feedstock production in order to mitigate CO2 emissions. Within a sensitivity analysis of UCG synthesis gas calorific value variations, we produce a range of capital and operational expenditure bandwidths that allow for an economic assessment of different synthesis gas end use approaches. To carry out the integrated techno-economic assessment of the coupled systems and the sensitivity analysis, we adapted the techno-economic UCG-CCS model developed by Nakaten et al. (2014). Our techno-economic modeling results demonstrate that the calorific value has a high impact on the economics of UCG synthesis gas utilization. In the underlying study, the synthesis gas is not suitable for an economic competitive electricity generation, due to the relatively low calorific value of 4.5 MJ/Nm³. To be a profitable option for electricity
YUE WAN; HONG-WEI YANG; TOSHIHIKO MASUI
In China, combustion of fossil fuels and biomass has produced serious air pollution that does harm to human health. Based on dose-response relationships derived from epidemiological studies, the authors calculated the number of deaths and people with health problems which were thought to be attributable to China's air pollution in the year of 2000. In order to estimate the corresponding economic impacts from the national point of view, the general equilibrium approach was selected as an analysis tool for this study. A computable general equilibrium (CGE) model was constructed involving 39 sectors and 32 commodities.The human capital approach (HCA) was also used for comparison. The economic burden of disease for people estimated by HCA was equivalent to 1.26‰ (ranging from 0.44‰ to 1.84‰) of China's gross domestic product (GDP). China's GDP loss estimated by the general equilibrium approach reached 0.38‰ (ranging from 0.16‰ to 0.51‰). The difference between the two approaches and the implications of the results were discussed.
Wan, Yue; Yang, Hong-Wei; Masui, Toshihiko
In China, combustion of fossil fuels and biomass has produced serious air pollution that does harm to human health. Based on dose-response relationships derived from epidemiological studies, the authors calculated the number of deaths and people with health problems which were thought to be attributable to China's air pollution in the year of 2000. In order to estimate the corresponding economic impacts from the national point of view, the general equilibrium approach was selected as an analysis tool for this study. A computable general equilibrium (CGE) model was constructed involving 39 sectors and 32 commodities. The human capital approach (HCA) was also used for comparison. The economic burden of disease for people estimated by HCA was equivalent to 1.26 per thousand (ranging from 0.44 per thousand to 1.84 per thousand) of China's gross domestic product (GDP). China's GDP loss estimated by the general equilibrium approach reached 0.38 per thousand (ranging from 0.16 per thousand to 0.51 per thousand). The difference between the two approaches and the implications of the results were discussed. PMID:16544525
We present AceWiki, a prototype of a new kind of semantic wiki using the controlled natural language Attempto Controlled English (ACE) for representing its content. ACE is a subset of English with a restricted grammar and a formal semantics. The use of ACE has two important advantages over existing semantic wikis. First, we can improve the usability and achieve a shallow learning curve. Second, ACE is more expressive than the formal languages of existing semantic wikis. Our evaluation shows that people who are not familiar with the formal foundations of the Semantic Web are able to deal with AceWiki after a very short learning phase and without the help of an expert.
Hughes, Dyfrig; Charles, Joanna; Dawoud, Dalia; Edwards, Rhiannon Tudor; Holmes, Emily; Jones, Carys; Parham, Paul; Plumpton, Catrin; Ridyard, Colin; Lloyd-Williams, Huw; Wood, Eifiona; Yeo, Seow Tien
Trial-based economic evaluations are an important aspect of health technology assessment. The availability of patient-level data coupled with unbiased estimates of clinical outcomes means that randomised controlled trials are effective vehicles for the generation of economic data. However there are methodological challenges to trial-based evaluations, including the collection of reliable data on resource use and cost, choice of health outcome measure, calculating minimally important differences, dealing with missing data, extrapolating outcomes and costs over time and the analysis of multinational trials. This review focuses on the state of the art of selective elements regarding the design, conduct, analysis and reporting of trial-based economic evaluations. The limitations of existing approaches are detailed and novel methods introduced. The review is internationally relevant but with a focus towards practice in the UK. PMID:26753558
Full Text Available Angiotensin-converting enzyme (ACE regulates normal blood pressure and fluid homeostasis through its action in the renin-angiotensin-system (RAS. Ace-/- mice are smaller in size, have low blood pressure and defective kidney structure and functions. All of these defects are cured by transgenic expression of somatic ACE (sACE in vascular endothelial cells of Ace-/- mice. sACE is expressed on the surface of vascular endothelial cells and undergoes a natural cleavage secretion process to generate a soluble form in the body fluids. Both the tissue-bound and the soluble forms of ACE are enzymatically active, and generate the vasoactive octapeptide Angiotensin II (Ang II with equal efficiency. To assess the relative physiological roles of the secreted and the cell-bound forms of ACE, we expressed, in the vascular endothelial cells of Ace-/- mice, the ectodomain of sACE, which corresponded to only the secreted form of ACE. Our results demonstrated that the secreted form of ACE could normalize kidney functions and RAS integrity, growth and development of Ace-/- mice, but not their blood pressure. This study clearly demonstrates that the secreted form of ACE cannot replace the tissue-bound ACE for maintaining normal blood pressure; a suitable balance between the tissue-bound and the soluble forms of ACE is essential for maintaining all physiological functions of ACE.
This work treats on the hypothesis that the American imperialism uses its nuclear arsenal for reforming geographical spaces that allow him to impel its economic development in the context of the progressive exhaustion of the natural resources of the planet and of the ferocious dispute for market niches and investment destinations, and like the political and military decisions crawl to the different scenarios of economic competition. In the chapter 1 it is insinuated like has been reproduced the Warlike-industrial Complex (CBI) American from the second world postwar period until the present time in the idea of explaining like it is that it is valorized to the capital in scale enlarged starting from the denominated sector producing of destruction means and understanding that the system specifically capitalist is a system where continually the is destroyed previously taken place to manufacture a new merchandise in a luck of creative destruction. In the chapter 2, the topic of the specific contradictions of the CBI is approached that disable him to be the tip of lance of the world imperialism. The chapter 3 try on the productive linkages in the production of nuclear bombs, as well as in the production of the vectors of nuclear transportation and on the implications derived for the world security of the different industries associated to the nuclear energy (as the petroleum, the electricity, the natural gas) and to the transportation vectors of these locating which you/they are the different States where the world supremacy is disputed and that they have like one of its so many negotiation-confrontation letters its nuclear strategic arsenals. What is looked for in a thermonuclear war is the enemy's total elimination, from their offensive capacity, their defensive capacity, until their supplies, their reservations, etc., with the result that the chapters 4 and 5 of this thesis are presented to offer a better understanding that they mean the nuclear arsenals in the
Bustamante-Ara, Natalia; Santiago Dorrego, Catalina; Verde Rello, Zoraida; Yvert, Thomas; Gómez Gallego, Félix; Rodríguez Romo, Gabriel; González Gil, Pedro; Serra-Rexach, José A.; Ruiz, Jonatan R.; Lucía Mulas, Alejandro
We studied the association of ACE and ACTN3 polymorphisms with skeletal muscle phenotypes (i. e. upper and lower body muscular strength and functional tests) in Spanish nonagenarian subjects [n=41, 33 women, 8 men, age: 90-97 years]. Mean values of the study phenotypes were not significantly different (all P>0.05) between ACE and ACTN3 genotypes. The analyses of the combined effects between genotypes ( ACE DD & ACTN3 RR/RX vs. ACE II/ID & ACTN3 XX) did not yield any significant difference. Ou...
Taddei, Stefano; Bortolotto, L
Historically, the first described effect of an angiotensin converting enzyme (ACE) inhibitor was an increased activity of bradykinin, one of the substrates of ACE. However, in the subsequent years, molecular models describing the mechanism of action of ACE inhibitors in decreasing blood pressure and cardiovascular risk have focused mostly on the renin-angiotensin system. Nonetheless, over the last 20 years, the importance of bradykinin in regulating vasodilation, natriuresis, oxidative stress, fibrinolysis, inflammation, and apoptosis has become clearer. The affinity of ACE appears to be higher for bradykinin than for angiotensin I, thereby suggesting that ACE inhibitors may be more effective inhibitors of bradykinin degradation than of angiotensin II production. Data describing the effect of ACE inhibition on bradykinin signaling support the hypothesis that the most cardioprotective benefits attributed to ACE inhibition may be due to increased bradykinin signaling rather than to decreased angiotensin II signaling, especially when high dosages of ACE inhibitors are considered. In particular, modulation of bradykinin in the endothelium appears to be a major target of ACE inhibition. These new mechanistic concepts may lead to further development of strategies enhancing the bradykinin signaling. PMID:27260014
This report explains installation of ACE/ONED code, structure of input and output, how to prepare input and introduces some sample inputs. ACE/ONED developed by KAERI is a two-group one-dimensional diffusion theory code for nuclear design and reactor simulations. The usage of ACE/ONED encompasses core follow calculation, load-following calculation, plant power control simulation, xenon oscillation simulation, control rod maneuvering, and so on. ACE/ONED programmed of FORTRAN 77 in most part can be run on almost all kinds of computer including personal computer. 4 tabs., 4 figs., 8 refs. (Author) .new
The environmental/economic dispatch (EED) is an important daily optimization task in the operation of many power systems. It involves the simultaneous optimization of fuel cost and emission objectives which are conflicting ones. The EED problem can be formulated as a large-scale highly constrained nonlinear multiobjective optimization problem. In recent years, many metaheuristic optimization approaches have been reported in the literature to solve the multiobjective EED. In terms of metaheuristics, recently, scatter search approaches are receiving increasing attention, because of their potential to effectively explore a wide range of complex optimization problems. This paper proposes an improved scatter search (ISS) to deal with multiobjective EED problems based on concepts of Pareto dominance and crowding distance and a new scheme for the combination method. In this paper, we have considered the standard IEEE (Institute of Electrical and Electronics Engineers) 30-bus system with 6-generators and the results obtained by proposed ISS algorithm are compared with the other recently reported results in the literature. Simulation results demonstrate that the proposed ISS algorithm is a capable candidate in solving the multiobjective EED problems. - Highlights: ► Economic dispatch. ► We solve the environmental/economic economic power dispatch problem with scatter search. ► Multiobjective scatter search can effectively improve the global search ability
Full Text Available One of the obvious trends in current business environment is the increased competition. In this context, organizations are becoming more and more aware of the importance of knowledge as a key factor in obtaining competitive advantage. A possible solution in knowledge management is Economic Intelligence (EI that involves the collection, evaluation, processing, analysis, and dissemination of economic data (about products, clients, competitors, etc. inside organizations. The availability of massive quantities of data correlated with advances in information and communication technology allowing for the filtering and processing of these data provide new tools for the production of economic intelligence.The research is focused on innovative aspects of economic intelligence process (models of analysis, activities, methods and informational tools and is providing practical guidelines for initiating this process. In this paper, we try: (a to contribute to a coherent view on economic intelligence process (approaches, stages, fields of application; b to describe the most important models of analysis related to this process; c to analyze the activities, methods and tools associated with each stage of an EI process.
Full Text Available This paper presents an economics-based approach for studying the problem of resource allocation among software development phases. Our approach is structured along two parallel axes: theoretical and empirical. We developed a general economic model for analyzing the allocation problem as a constrained profit maximization problem. The model, based on a novel concept of software production function, considers the effects of different allocations of development resources on output measures of the resulting software product. An empirical environment for evaluating and refining the model is presented, and a first exploratory study for characterizing the model's components and developers' resource allocation decisions is described. The findings illustrate how the model can be applied and validate its underlying assumptions and usability. Future quantitative empirical studies can refine and substantiate various aspects of the proposed model and ultimately improve the productivity of software development processes.
This study builds a monetary growth model with inflation policy and education. The model is a synthesis of the Uzawa-Lucas two-sector growth model and traditional monetary model with the money-in-utility (MIU) approach. We show how money, physical capital and human capital interact over time under exogenous inflation policy in a free market economy. The dynamics of the economy is described by three differential equations. We show that the monetary economic system has a saddle equilibrium poin...
Bunyaratavej Kraiwinee; Hahn Eugene D.
Empirical convergence analyses have helped provide insight as to whether economies are converging. Previous works on convergence have tended to focus on a particular economic indicator exclusively, even though the convergence process has multiple components. Improved estimates of convergence are likely to result from an integrated approach wherein several indicators are considered simultaneously. The proposed model integrates convergence analyses for three convergence variables to estimate th...
Hajamini, Mehdi; Falahi, Mohammad Ali
In the growth literature, there is a nonlinear relationship between economic growth and government size, which is similar to an inverted U-shaped curve. This curve can be used to determine the optimum share of government expenditures. This paper, using threshold panel approach, attempts to investigate this nonlinear effect for 15 European countries, empirically. For the size of government, four measures are considered as follows: (i) total expenditures to gross domestic product, (ii) final co...
This paper examines the dynamic causal relationships between foreign direct investment (FDI), trade and economic growth in India by applying the bounds testing (ARDL) approach to cointegration for the period from 1970 to 2012. The bounds tests suggest that the variables of interest are bound together in the long-run when GDP per capita is the dependent variable. The empirical findings confirm that there is bi-directional Granger causality between FDI and trade, unidirectional Granger causalit...
Claudy, Marius; O'Driscoll, Aidan
This paper argues that the moderate success of policies aiming to stimulate the uptake of Sustainable Energy Systems (SES) in the domestic sector is grounded in a poor understanding of the ‘consumer’. The predominant economic approach behind most policies assumes that improving the cost-benefit ratio of technologies via grants and subsidies and providing sufficient information will automatically incentivise householders’ to invest into SES. Yet, policymakers often neglect behavioural determin...
João Carlos Lopes; Tanya Araujo
This paper contributes to further understanding the economic performance of Portuguese and Spanish regions, using a stochastic network approach. The empirical analysis is made at the territorial level of NUT 3 regions and covers the period 1995-2008. The performance of regions is based on GDP per capita at Purchasing Power Standards. The network analysis is based on a metric space built from the correlation coefficients between the log-difference of annual growth rates. The metric space and t...
Lopes, João Carlos; Araújo, Tânya
This paper contributes to further understanding the economic performance of Portuguese and Spanish regions, using a stochastic network approach. The empirical analysis is made at the territorial level of NUT 3 regions and covers the period 1995-2008. The performance of regions is based on GDP per capita at Purchasing Power Standards. The network analysis is based on a metric space built from the correlation coefficients between the log-difference of annual growth rates. The metric space an...
Volkov V. A.; Orlov A. I.
In this article we propose a general theoretical model of estimation of the feasibility of an innovation-investment project. For specifying a general model to estimate the feasibility of a project we have highlighted the stages of development of projects in the aerospace industry. Organizational-economic approaches to estimation of the feasibility of projects to create rocket and space technology are presented in terms of algorithms. They take into account the specifics of the space industry,...
This paper will discuss a new approach to studying finance-growth nexus, based on the production inputs. We analyze, from a panel of 93 countries (developed countries and least developed countries) over the period 1972-2012, the standard regress of economic growth as well as a new proxy for financial activity and interaction effects of the latter with catching up, education, and physical capital accumulation. The results of the Least Squares Dummy Variable estimator show that, from a global p...
This paper presents a novel heuristic optimization approach to constrained economic load dispatch (ELD) problems using the adaptive-variable population - PSO technique. The proposed methodology easily takes care of different constraints like transmission losses, dynamic operation constraints (ramp rate limits) and prohibited operating zones and also accounts for non-smoothness of cost functions arising due to the use of multiple fuels. Simulations were performed over various systems with different numbers of generating units, and comparisons are performed with other existing relevant approaches. The findings affirmed the robustness, fast convergence and proficiency of the proposed methodology over other existing techniques
Larson, Kyle B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tagestad, Jerry D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Perkins, Casey J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Oster, Matthew R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Warwick, M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Geerlofs, Simon H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
This study was conducted with the support of the U.S. Department of Energy’s (DOE’s) Wind and Water Power Technologies Office (WWPTO) as part of ongoing efforts to minimize key risks and reduce the cost and time associated with permitting and deploying ocean renewable energy. The focus of the study was to discuss a possible approach to exploring scenarios for ocean renewable energy development in Hawaii that attempts to optimize future development based on technical, economic, and policy criteria. The goal of the study was not to identify potentially suitable or feasible locations for development, but to discuss how such an approach may be developed for a given offshore area. Hawaii was selected for this case study due to the complex nature of the energy climate there and DOE’s ongoing involvement to support marine spatial planning for the West Coast. Primary objectives of the study included 1) discussing the political and economic context for ocean renewable energy development in Hawaii, especially with respect to how inter-island transmission may affect the future of renewable energy development in Hawaii; 2) applying a Geographic Information System (GIS) approach that has been used to assess the technical suitability of offshore renewable energy technologies in Washington, Oregon, and California, to Hawaii’s offshore environment; and 3) formulate a mathematical model for exploring scenarios for ocean renewable energy development in Hawaii that seeks to optimize technical and economic suitability within the context of Hawaii’s existing energy policy and planning.
Craig W. Herbold
Full Text Available High throughput sequencing of phylogenetic and functional gene amplicons provides tremendous insight into the structure and functional potential of complex microbial communities. Here, we introduce a highly adaptable and economical PCR approach to barcoding and pooling libraries of numerous target genes. In this approach, we replace gene- and sequencing platform-specific fusion primers with general, interchangeable barcoding primers, enabling nearly limitless customized barcode-primer combinations. Compared to barcoding with long fusion primers, our multiple-target gene approach is more economical because it overall requires lower number of primers and is based on short primers with generally lower synthesis and purification costs. To highlight our approach, we pooled over 900 different small-subunit rRNA and functional gene amplicon libraries obtained from various environmental or host-associated microbial community samples into a single, paired-end Illumina MiSeq run. Although the amplicon regions ranged in size from approximately 290 to 720 bp, we found no significant systematic sequencing bias related to amplicon length or gene target. Our results indicate that this flexible multiplexing approach produces large, diverse and high quality sets of amplicon sequence data for modern studies in microbial ecology.
Bayerstadler, Andreas; Benstetter, Franz; Heumann, Christian; Winter, Fabian
Predictive Modeling (PM) techniques are gaining importance in the worldwide health insurance business. Modern PM methods are used for customer relationship management, risk evaluation or medical management. This article illustrates a PM approach that enables the economic potential of (cost-) effective disease management programs (DMPs) to be fully exploited by optimized candidate selection as an example of successful data-driven business management. The approach is based on a Generalized Linear Model (GLM) that is easy to apply for health insurance companies. By means of a small portfolio from an emerging country, we show that our GLM approach is stable compared to more sophisticated regression techniques in spite of the difficult data environment. Additionally, we demonstrate for this example of a setting that our model can compete with the expensive solutions offered by professional PM vendors and outperforms non-predictive standard approaches for DMP selection commonly used in the market. PMID:23780751
C, Aucelli, Pietro P.; Balteanu, Dan; Pisano, Luca; Rosskopf, Carmen M.; Zumpano, Veronica
Land degradation due to mass wasting and accelerated water erosion represents at global scale a serious threat to socio-economic development not only in urban areas but also in rural and hence less populated territories where the main economic resources are frequently directly linked to the exploitation of the agricultural, pastoral and natural resources, often threatened especially by landslide phenomena. The assessment of damage induced by landslides, thus, provides an important contribution to support decision making concerning the sustainable management of land use. In this paper a methodological approach developed in GIS environment for valuing the economic damage induced by landslides in rural areas is presented. It allows direct damage estimation related to landslide phenomena by means of a synthetic approach which considers the loss of land value associated with landslides state of activity. This approach was tested in a study area (a small-scale catchment in Molise Region, Southern Italy) which is highly representative of the Adriatic flank of the Molise Apennine, highly exploited for farming and, in the same time, very sensible to slope instability. Several environmental calculation matrices were defined at the pixel scale in relation to different states of activity of landslides. For each cell, soil uses and related Average Agricultural Values (AAVs) were determined. The economic damage value (DV) was computed by multiplying the obtained specified AAV with a specific landslide-damage index (LDI) which was calculated on the basis of the extent and state of activity of landslides within each cell. This procedure allowed the estimation of the DV and the real agricultural value for each cell. Summing up the results coming from each cell, the total loss of land value due to landslides and the residual total agricultural value for the entire study area were calculated. Furthermore, in order to assess for the entire study area the landslide exposition of rural
Jackson, B.; Cubela, R.B.; Sakaguchi, K.; Johnston, C.I.
Angiotensin converting enzyme (ACE) was characterized by radioligand studies utilizing the potent ACE inhibitor 351A, a derivative of lisinopril. Ligand binding characteristics were similar for ACE derived from testis, lung, and kidney, despite known differences in structure between ACe from these sources. This observation suggests that the ACE active enzymatic site is similar in different tissues. The effect of the orally active ACE inhibitor perindopril was studied ex vivo in tissues of the rat after oral gavage. Radioligand bound to tissue ACE was reduced after perindopril treatment, in tissue homogenates of lung and kidney, but not testis. Autoradiographs of radioligand binding to tissue sections obtained ex vivo after oral perindopril showed inhibition of ACE in the aorta, lung, and kidney, but did not reveal any inhibition of ACE in the testis. ACE in small vessels of the testis was inhibited as in the aorta, while at the same time testicular ACE was unaffected. ACE in rat testis appears to have a similar enzymatic binding site to ACE from the lung and kidney. Perindopril inhibited ACE in the lung and kidney but did not affect ACE in the testis, suggesting the drug is limited in testicular penetration by the blood-testis barrier. This may explain the lack of any reports of adverse effects of ACE inhibitors on testicular function.
Bleumink, GS; Schut, Anna F.C.; Sturkenboom, MCJM; van Duijn, CM; Deckers, JW; Hofman, A; Kingma, J. Herre; Witteman, JCM; Stricker, BHC
Background The response to angiotensin-l converting enzyme (ACE)-inhibitor therapy is highly variable. Residual ACE activity during treatment, potentially modified by the ACE insertion/deletion (I/D) polymorphism, may explain part of this variability. We studied the possible interaction between ACE-
... High Blood Pressure: Is an ACE Inhibitor Drug Right for You? What are ACE inhibitors? ACE inhibitors, ... talk with your doctor about which drugs are right for you. If your blood pressure is slightly ...
Full Text Available The paper emphasizes the economic performance of the fresh European sea bass production and profitability of related processing to value-added fillets. Croatian annual farmed European sea bass and gilthead sea bream production in amount of 4,000 tones plays only about 1.7% of the World production with mediocre economic benefits for producers. However, product diversification, including processing measures as filleting, vacuuming and smoked processing can ensure additional product value providing long-term strategic orientation for fish-farmers. Seabass filleting, although at the initial phase, can be a modus of value-added production, which protects the producers of the price risk volatility targeting the population averse to the long lasting traditional fish mill preparation. Applied Real Option method can be helpful tool in the situation when the strategic project value includes not just the current economic features but also opportunities related to the basic model. Option approach indicates that seabass filleting triplicate the economic performance with respect to fresh seabass production.
Full Text Available During 1989, the moment of changes in Eastern Europe, in socialist countries political system were transformed, by renouncing communism, and adopting market based economy. The process had major implications on economic systems in countries such Romania, Bulgaria, Hungary, Poland, Czechoslovakia, that from that moment engaged in wide-ranging political, social, economic and institutional reforms. The year 1989 also marked the beginning of the transition from socialist economy to a market economy to centralized countries mentioned, a process with profound implications on the economic system and financial default. This important structural reforms necessary functioning new economic framework and assumed behavior modification specific old economy, focused on socialist property, presumably achieve in conditions of relative stability allowing rapidly and sustainable growth. This paper takes into discussion some models used by FMI and World Bank (WB that had implications on financial policy applied in transition country, referring to absorption theory, monetary approach to balance of payment and stabilization programs, as short terms models, respectively.
Di Cagno, Alessandra; Sapere, Nadia; Piazza, Marina; Aquino, Giovanna; Iuliano, Enzo; Intrieri, Mariano; Calcagno, Giuseppe
In the angiotensin-converting enzyme (ACE) gene, Alu deletion, in intron 16, is associated with higher concentrations of ACE serum activity and this may be associated with elite sprint and power performance. The Alu insertion is associated with lower ACE levels and this could lead to endurance performance. Moreover, recent studies have identified a single-nucleotide polymorphism of the angiotensin type 1 receptor gene AGTR1, which seems to be related to ACE activity. The aim of this study was to examine the involvement of the ACE and the AGTR1 gene polymorphisms in 28 Italian elite rhythmic gymnasts (age range 21 ± 7.6 years), and compare them to 23 middle level rhythmic gymnasts (age range 17 ± 10.9 years). The ACE D allele was significantly more frequent in elite athletes than in the control population (χ(2)=4.07, p=0.04). Comparisons between the middle level and elite athletes revealed significant differences (p<0.0001) for the ACE DD genotype (OR=6.48, 95% confidence interval=1.48-28.34), which was more frequent in elite athletes. There were no significant differences in the AGTR1 A/C genotype or allele distributions between the middle level and elite athletes. In conclusion, the ACE D allele genotype could be a contributing factor to high-performance rhythmic gymnastics that should be considered in athlete development and could help to identify which skills should be trained for talent promotion. PMID:23145508
Cox, Clara B.
Diane Bell, professor of anthropology and director of women's studies at George Washington University and one of 37 American Council on Education (ACE) Fellows, will spend the current academic year in the provost's office at Virginia Tech, examining the globalization efforts of the university and its core curriculum as part of her ACE fellowship.
Full Text Available The article discusses the widely used classic method of analysis, forecasting and decision-making in the various economic problems, called SWOT analysis. As known, it is a qualitative comparison of multicriteria degree of Strength, Weakness, Opportunity, Threat for different kinds of risks, forecasting the development in the markets, status and prospects of development of enterprises, regions and economic sectors, territorials etc. It can also be successfully applied to the evaluation and analysis of different project management tasks - investment, innovation, marketing, development, design and bring products to market and so on. However, in practical competitive market and economic conditions, there are various uncertainties, ambiguities, vagueness. Its making usage of SWOT analysis in the classical sense not enough reasonable and ineffective. In this case, the authors propose to use fuzzy logic approach and the theory of fuzzy sets for a more adequate representation and posttreatment assessments in the SWOT analysis. In particular, has been short showed the mathematical formulation of respective task and the main approaches to its solution. Also are given examples of suitable computer calculations in specialized software Fuzicalc for processing and operations with fuzzy input data. Finally, are presented considerations for interpretation of the results.
Nuclear power plants (NPPs) with water cooled reactors [either light water reactors (LWRs) or heavy water reactors (HWRs)] constitute the large majority of the currently operating plants. Water cooled reactors can make a significant contribution to meeting future energy needs, to reducing greenhouse gas emissions, and to energy security if they can compete economically with fossil alternatives, while continuing to achieve a very high level of safety. It is generally agreed that the largest commercial barrier to the addition of new nuclear power capacity is the high capital cost of nuclear plants relative to other electricity generating alternatives. If nuclear plants are to form part of the future generating mix in competitive electricity markets, capital cost reduction through simplified designs must be an important focus. Reductions in operating, maintenance and fuel costs should also be pursued. The Department of Nuclear Energy of the IAEA is examining the competitiveness of nuclear power and the means for improving its economics. The objective of this TECDOC is to emphasize the need, and to identify approaches, for new nuclear plants with water cooled reactors to achieve competitiveness while maintaining high levels of safety. The cost reduction methods discussed herein can be implemented into plant designs that are currently under development as well as into designs that may be developed in the longer term. Many of the approaches discussed also generally apply to other reactor types (e.g. gas cooled and liquid metal cooled reactors). To achieve the largest possible cost reductions, proven means for reducing costs must be fully implemented, and new approaches described in this document should be developed and implemented. These new approaches include development of advanced technologies, increased use of risk-informed methods for evaluating the safety benefit of design features, and international consensus regarding commonly acceptable safety requirements that
Badari, V S
Developing countries are experiencing rapid population growth, which hinders development of economic planning. There are 2 ways to determine the gain to the economy resulting from preventing a birth: a macro-economic growth approach, which establishes a comparison of the income per capita of a country with and without fertility control, and the investment approach which weighs the advantages and disadvantages of additional births in terms of the anticipated future production and consumption of these births, compared with the gain of preventing them. If decrease of population growth helps development planning, it makes sense to establish incentive payments for preventing a birth. Arguments against the investment approach are: the amount spent for bonuses could be higher than the amount saved; it could be used for new investment. In the discounting procedure, consumption has been exagerated while reducing the value of production. Leibenstein's contention is that family programs are followed more by middle class families, whose children won't become marginal workers. These critics have been refuted. Enke, main contributor to this approach, states that the incentive payment should not exceede the value of preventing a birth. Also, to avoid the cost of resources the bonus could be given in services and productive goods. The discounting procedure has been considered valid in those cases in which present consumption is more relevant than future consumption and investible funds, in which case discounting is unavoidable. On the other hand, if incentives are offered, more participation of the poorer classes can be expected. Based on the investment approach, some economists, like Enke and Badari, analized the worth of an averted birth in India and agreed that the gains were substantial. This indicated that the investment approach is a useful guide for developing countries. PMID:12261074
This study deals with estimation of energy demand based on economic indicators in Turkey. The genetic algorithm energy demand (GAEDM) Model is developed based on past data using the genetic algorithm approach. The economic indicators that are used during the model development are: gross national product (GNP), population and import and export figures of Turkey. Two forms of the GAEDM model are developed to estimate energy demand. The GAEDM can be used for estimating the energy demand in the future by optimizing the parameter value using available data. The future energy demand is calculated under different scenarios. The current models overestimate the energy demand in the years 2020 and 2025. The relative estimation errors of the GAEDM model are the lowest when they are compared with the Ministry of Energy and Natural Resources (MENR) projection
Changhyup Park; Joe M.Kang; Taewoong Ahn
The paper presents a stochastic and economic analysis for petroleum development under uncertain market and technical environments. Mean-reversion with jumps for price forecasting is used to consider market uncertainty, while various scenarios for the reservoir properties and cost are employed to consider technical uncertainty. Monte Carlo simulation is carried out to obtain the feasible range of net present values and internal rates of return. The influence of stochastic parameters is examined through correlation coefficients. The stochastic approach yields more reliable evaluation and effectively investigates the characteristics of development. The integration of uncertainties and contractual terms results in an irregular tendency in the future cash flow and reveals that a larger reserve does not guarantee a greater profit. The reserve and the well rate affect the economic values whereas the parameters for price prediction don't. The research confirms the necessity of qualifying uncertainties for realistic decision-making at the initial stage of development.
The absence of a 287 base pair alu sequence in the ACE gene (D allele) is associated with higher ACE levels than its presence (I allele) in adults. We carried out a case control study of thr ACE*I/D dimorphism in relation to circulating ACE activities to evaluate associations between the two variables in adults, compared to younger (18 years or less) individuals. Genotypes of the ACE*I/D dimorphism were determined on DNA samples from a population of 164 random (unrelated) Emirtaes nationals, composed of groups: 112 subjects above 18 years of age (range=20-77), and 52 subjects of 18 years or less (range=1-18) and analyzed for putative associations with serum ACE activities. ACE*I/D genotypes of the 164 individualds were determined by assays based on polymerase chain reaction. ACE activities were determined on serum samples of these subjects bu colorimetric assays. The D allele was associared with increasd ACE values in both adult and younger individuals. Mean ACE activity levels associated with II, ID and DD genotypes, however, were 42%-61% higher in the 18 years and under group of subjects. The ACE*I/D marker accounted for 28% of the variance of the phenomenon determining ACE levels in adults, and for 30% among youngsters. The ACE*I/D dimorphism is correlated strongly with circulating ACE activities in both and young Emirati, subjects and the corresponding mean ACE activities were significantly higher among the youngsters. (author)
Claxton, K; Posnett, J
Whilst significant advances have been made in persuading clinical researchers of the value of conducting economic evaluation alongside clinical trials, a number of problems remain. The most fundamental is the fact that economic principles are almost entirely ignored in the traditional approach to trial design. For example, in the selection of an optimal sample size no consideration is given to the marginal costs or benefits of sample information. In the traditional approach this can lead to either unbounded or arbitrary sample sizes. This paper presents a decision-analytic approach to trial design which takes explicit account of the costs of sampling, the benefits of sample information and the decision rules of cost-effectiveness analysis. It also provides a consistent framework for setting priorities in research funding and establishes a set of screens (or hurdles) to evaluate the potential cost-effectiveness of research proposals. The framework permits research priority setting based explicitly on the budget constraint faced by clinical practitioners and on the information available prior to prospective research. It demonstrates the link between the value of clinical research and the budgetary restrictions on service provision, and it provides practical tools to establish the optimal allocation of resources between areas of clinical research or between service provision and research. PMID:9003938
Boot, Sander Paul
textabstractIn international water policy, a trend can be observed towards more attention for economic approaches in water management. In 1992, at the International Conference on Water and the Environment (ICWE) in Dublin, the Convention on the Protection and Use of Transboundary Water Courses and International Lakes was adopted. Guiding Principle 4 of this convention states that ‘water has an economic value in all its competing uses and should be recognised as an economic good’. The argument...
Dmytro Stechenko; Olga Omelchenko
The approach to the restructuring of engineering enterprises on the basis of economic and mathematical models complex and scenarios for its implementation are given in the article. The structure and features of the formation of organizational restructuring and economic provision are described. The components of economic and mathematical methods of restructuring are considered: a general model of restructuring, that determines the design of its planning, development and implementation; the ove...
Rozilee Asid; Mori Kogid; Dullah Mulok; Jaratin Lily
The main objective of present study is to investigate the implications of intellectual property rights (IPR) protection on foreign direct investment and economic growth in Malaysia. We used the ARDL bounds testing approach to cointegration for long run relationship between the variables. Although researches with regards to foreign direct investment and economic growth have been conducted extensively in the Malaysian economic context, the role of IPR protection however has yet to be discussed ...