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Sample records for accelerated stress studies

  1. Comparison of acceleration and impact stress as possible loading factors in phonation: a computer modeling study.

    Horácek, Jaromír; Laukkanen, Anne-Maria; Sidlof, Petr; Murphy, Peter; Svec, Jan G

    2009-01-01

    Impact stress (the impact force divided by the contact area of the vocal folds) has been suspected to be the main traumatizing mechanism in voice production, and the main cause of vocal fold nodules. However, there are also other factors, such as the repetitive acceleration and deceleration, which may traumatize the vocal fold tissues. Using an aeroelastic model of voice production, the present study quantifies the acceleration and impact stress values in relation to lung pressure, fundamental frequency (F0) and prephonatory glottal half-width. Both impact stress and acceleration were found to increase with lung pressure. Compared to impact stress, acceleration was less dependent on prephonatory glottal width and, thus, on voice production type. Maximum acceleration values were about 5-10 times greater for high F0 (approx. 400 Hz) compared to low F0 (approx. 100 Hz), whereas maximum impact stress remained nearly unchanged. This suggests that acceleration, i.e. the inertia forces, may present at high F0 a greater load for the vocal folds, and in addition to the collision forces may contribute to the fact that females develop vocal fold nodules and other vocal fold traumas more frequently than males. PMID:19571548

  2. A Study on the Storage Reliability of LSINS Based on Step-stress Accelerated Life Test

    Teng Fei

    2015-01-01

    Full Text Available Based on the step-stress accelerated life test and the laser strap-down inertial navigation system, this paper studies the accelerated life model and the test method, provides the likelihood function, the likelihood equation and the two-order derivative when the stress level is k, evaluates the effectiveness of the method with the simulation test model established by MATLAB, applies the research findings in the storage reliability study of the XX laser strap-down inertial navigation system, and puts forward an effective evaluation method of the storage life of the inertial navigation system.

  3. Traumatic stress, oxidative stress and posttraumatic stress disorder: neurodegeneration and the accelerated-aging hypothesis

    Miller, Mark W.; Sadeh, Naomi

    2014-01-01

    Posttraumatic stress disorder (PTSD) is associated with elevated risk for a variety of age-related diseases and neurodegeneration. In this paper, we review evidence relevant to the hypothesis that chronic PTSD constitutes a form of persistent life stress that potentiates oxidative stress (OXS) and accelerates cellular aging. We provide an overview of empirical studies that have examined the effects of psychological stress on OXS, discuss the stress-perpetuating characteristics of PTSD, and th...

  4. Accelerator research studies

    This progress report for the Accelerator Research Studies program at the University of Maryland covers the second year (June 1, 1989 to May 31, 1990) of the current three-year contract period from June 1, 1988 to May 31, 1991, funded by the Department of Energy under Contract No. AC05-85ER40216. The research program is divided into three separate tasks, as follows: the study of Transport and Longitudinal Compression of Intense, High-Brightness Beams; the study of Collective Ion Acceleration by Intense Electron Beams and Pulse-Powered Plasma Focus; the study of Microwave Sources and Parameter Scaling for High-Frequency Linacs. This report consists of three sections in which the progress for each task is documented separately. An introduction and synopsis is presented at the beginning of the progress report for each task

  5. Accelerator research studies

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy under contract number AC05-85ER40216-8, is currently in the third year of its three-year funding cycle. This Renewal Proposal requests DOE support for the next three-year period from June 1, 1991 to May 31, 1994. It documents the progress made during the past year and outlines the proposed research program for the next three years. The program consisted of the following three tasks: Task A, ''Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams,'' Task B, ''Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams,'' Task C, ''Study of a Gyroklystron High-Power Microwave Source for Linear Colliders.'' These tasks will be discussed in this paper

  6. Accelerator research studies

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy under grant number DE-FG05-91ER40642, is currently in the second year of a three-year funding cycle. The program consists of the following three tasks: TASK A, ''Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams,'' (P.I., M. Reiser); TASK B, ''Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams,'' (Co-P.I.'s, W.W. Destler, M. Reiser, M.J. Rhee, and C.D. Striffler); TASK C, ''Study of a Gyroklystron High-Power Microwave Source for Linear Colliders,'' (Co-P.I.'s, V.L. Granatstein, W. Lawson, M. Reiser, and C.D. Striffler). In this report we document the progress that has been made during the past year for each of the three tasks

  7. Accelerator research studies

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy under grant number DE-FG05-91ER40642, is currently in the first year of a three-year funding cycle. The program consists of the following three tasks: TASK A, Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams, TASK B, Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams; TASK C, Study of a Gyroklystron High-power Microwave Source for Linear Colliders. In this report we document the progress that has been made during the past year for each of the three tasks

  8. Accelerator research studies

    1993-01-01

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy under grant number DE-FG05-91ER40642, is currently in the second year of a three-year funding cycle. The program consists of the following three tasks: TASK A, Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams,'' (P.I., M. Reiser); TASK B, Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams,'' (Co-P.I.'s, W.W. Destler, M. Reiser, M.J. Rhee, and C.D. Striffler); TASK C, Study of a Gyroklystron High-Power Microwave Source for Linear Colliders,'' (Co-P.I.'s, V.L. Granatstein, W. Lawson, M. Reiser, and C.D. Striffler). In this report we document the progress that has been made during the past year for each of the three tasks.

  9. 丁腈橡胶应力加速老化行为的研究%Study of Stress Accelerated Aging Behavior of Sulfured Nitrile-butadiene Rubber

    熊英; 付宝强; 郭少云; 芦忠

    2012-01-01

    The storage life of nitrile-butadiene rubber (NBR) was calculated according to Arrhenius equation by using high temperature accelerated aging method and the criterion of elongation. The aging behavior of NBR under different stress was studied and the aging mechanism was discussed. The results showed that stress has important impact on aging behavior of NBR; when there is no stress, NBR's storage life is over 19 years according to Arrhenius equation; its storage life reduces 50% under bending stress; its storage life is less than 2 years under tensile-bending stress. This is because stress will induce the orientation and deformation of NBR molecular chain, and change and restrain its bond lengths and bond angles, which also reduce the breaking activation energy of the molecular chain, accelerate the aging process, and shorten the storage life or the service life of NBR.%以丁腈橡胶为例,采用高温加速老化法,以拉伸断裂伸长率作为贮存寿命指标,通过Arrhenius方程对丁腈橡胶贮存寿命的推算,研究了不同应力作用下丁腈橡胶的老化行为,并初步探讨了应力作用下丁腈橡胶的老化机理.结果表明,应力作用对丁腈橡胶的老化行为有较大影响,当丁腈橡胶不承受任何应力作用时,采用Arrhenius方程推算其在常温下的贮存寿命超过19a;受弯曲应力作用时,其贮存寿命降低了50%;在拉伸应力和弯曲应力同时作用时,其贮存寿命小于2a.原因是在应力作用下丁腈橡胶的分子链发生取向变形,键长和键角发生改变并受到约束,分子链的断裂活化能降低、老化进程加快,寿命缩短.

  10. Estimation in Step-Stress Accelerated Life Tests for Power Generalized Weibull Distribution with Progressive Censoring

    M. M. Mohie EL-Din

    2015-01-01

    Full Text Available Based on progressive censoring, step-stress partially accelerated life tests are considered when the lifetime of a product follows power generalized Weibull distribution. The maximum likelihood estimates (MLEs and Bayes estimates (BEs are obtained for the distribution parameters and the acceleration factor. In addition, the approximate and bootstrap confidence intervals (CIs of the estimators are presented. Furthermore, the optimal stress change time for the step-stress partially accelerated life test is determined by minimizing the asymptotic variance of MLEs of the model parameters and the acceleration factor. Simulation results are carried out to study the precision of the MLEs and BEs for the parameters involved.

  11. An Accelerated Stress Test Method for Electrostatically Driven MEMS Devices

    Ruan, Jinyu Jason; Monnereau, Nicolas; Trémouilles, David; Mauran, Nicolas; Coccetti, Fabio; Nolhier, Nicolas; Plana, Robert

    2012-01-01

    This paper addresses an innovative solution to develop a circuit to perform accelerated stress tests of capacitive microelectromechanical-system (MEMS) switches and shows the use of instruments and equipment to monitor physical aging phenomena. A dedicated test circuit was designed and fabricated in order to meet the need for accelerated techniques for those structures. It integrated an in-house miniaturized circuit connected to additional test equipment (e.g., oscilloscopes and capacitance m...

  12. Biomarkers of oxidant stress, insulin sensitivity and endothelial activation in rheumatoid arthritis: a cross-sectional study of their association with accelerated atherosclerosis

    Walker Michael G

    2009-05-01

    Full Text Available Abstract Background Women with rheumatoid arthritis (RA have increased morbidity and mortality due to coronary heart disease. Chronic systemic inflammation is known to accelerate atherosclerosis and increase arterial stiffness in patients, but other mechanisms may also be involved. Biomarkers of oxidant stress, inflammation, insulinaemia and endothelial dysfunction were measured in blood and urine from 46 RA patients and 48 age-matched controls. Plaque formation and intima-medial thickness (IMT were measured using B-mode carotid Doppler scan. Findings The prevalence of plaque was increased (p = 0.042 in RA patients between 50–59 years old compared to the same age group in controls. 8-isoprostane (p = 0.004, C-reactive protein (p Conclusion The burden of atherosclerosis is particularly increased in middle-aged women with RA. Patients with RA have increased levels of oxidant stress, inflammation, insulin and soluble adhesion molecules. As the association between classical risk factors was much weaker in RA patients compared to controls, these additional factors may be more important in the accelerated development of atheroma in RA.

  13. Bayesian optimal design of step stress accelerated degradation testing

    Xiaoyang Li; Mohammad Rezvanizaniani; Zhengzheng Ge; Mohamed Abuali; Jay Lee

    2015-01-01

    This study presents a Bayesian methodology for de-signing step stress accelerated degradation testing (SSADT) and its application to batteries. First, the simulation-based Bayesian de-sign framework for SSADT is presented. Then, by considering his-torical data, specific optimal objectives oriented Kul back–Leibler (KL) divergence is established. A numerical example is discussed to il ustrate the design approach. It is assumed that the degrada-tion model (or process) fol ows a drift Brownian motion;the accele-ration model fol ows Arrhenius equation; and the corresponding parameters fol ow normal and Gamma prior distributions. Using the Markov Chain Monte Carlo (MCMC) method and WinBUGS software, the comparison shows that KL divergence is better than quadratic loss for optimal criteria. Further, the effect of simulation outliers on the optimization plan is analyzed and the preferred sur-face fitting algorithm is chosen. At the end of the paper, a NASA lithium-ion battery dataset is used as historical information and the KL divergence oriented Bayesian design is compared with maxi-mum likelihood theory oriented local y optimal design. The results show that the proposed method can provide a much better testing plan for this engineering application.

  14. Study on superconducting accelerating cavities

    A test cavity of cylindrical shape has been designed and constructed to study superconducting accelerating cavities for TRISTAN e+e- Ring. Higher order modes have been calculated by using SUPERFISH program and an analytical method, and measured. The measured resonant frequencies well agree with the calculated results. (author)

  15. Long-term moderate exercise accelerates the recovery of stress-evoked cardiovascular responses.

    Hsu, Yuan-Chang; Tsai, Sheng-Feng; Yu, Lung; Chuang, Jih-Ing; Wu, Fong-Sen; Jen, Chauying J; Kuo, Yu-Min

    2016-01-01

    Psychological stress is an important global health problem. It is well documented that stress increases the incidences of various cardiovascular disorders. Regular exercise is known to reduce resting blood pressure (BP) and heart rate (HR). This study was designed to clarify the effects of long-term exercise on stress-evoked cardiovascular responses and to emphasize post-stress recovery effects. Male Wistar rats underwent 8 weeks of moderate treadmill training, with cardiovascular responses, autonomic nervous system activities and local Fos reactivity changes in the cardiovascular regulation center were monitored before, during and after immobilization stress. A spectral analysis of cardiovascular parameters was used to examine autonomic nervous activities. We found that long-term exercise (i) lowered resting BP, HR and sympathetic activity, but increased resting parasympathetic activity and baroreflex sensitivity (BRS); (ii) accelerated post-stress recovery of stress-evoked cardiovascular and sympathetic responses along with increased BRS and (iii) accelerated post-stress recovery of stress-evoked neuron activations in the paraventricular nucleus, but delayed it in the nucleus of the tractus solitarius. We conclude that, in rats, long-term exercise accelerated recovery of stress-evoked cardiovascular responses differentially altering hypothalamic and medullar neuron activities. PMID:26473638

  16. Sustained acceleration of colonic transit following chronic homotypic stress in oxytocin knockout mice.

    Babygirija, Reji; Bülbül, Mehmet; Cerjak, Diana; Ludwig, Kirk; Takahashi, Toku

    2011-05-01

    Acute restraint stress delays gastric emptying and accelerates colonic transit via central corticotropin releasing factor (CRF) in rats. In contrast, central oxytocin has anxiolytic effects and attenuates the hypothalamus-pituitary-adrenal (HPA) axis in response to stress. Our recent study showed that up regulated oxytocin expression attenuates hypothalamic CRF expression and restores impaired gastric motility following chronic homotypic stress in mice. We studied the effects of acute and chronic homotypic stress on colonic transit and hypothalamic CRF mRNA expression in wild type (WT) and oxytocin knockout (OXT-KO) mice. Colonic transit was measured following acute restraint stress or chronic homotypic stress (repeated restraint stress for 5 consecutive days). (51)Cr was injected via a catheter into the proximal colon. Ninety minutes after restraint stress loading, the entire colon was removed. The geometric center (GC) was calculated to evaluate colonic transit. Expression of CRF mRNA in the supraoptic nucleus (SON) was measured by real time RT-PCR. Colonic transit was significantly accelerated following acute stress in WT (GC=8.1±0.8; n=7) and OXT KO mice (GC=9.4±0.3; n=7). The accelerated colonic transit was significantly attenuated in WT mice (GC=6.6±0.5; n=9) following chronic homotypic stress while it was still accelerated in OXT KO mice (GC=9.3±0.5; n=8). The increase in CRF mRNA expression at the SON was much greater in OXT-KO mice, compared to WT mice following chronic homotypic stress. It is suggested that oxytocin plays a pivotal role in mediating the adaptation mechanism following chronic homotypic stress in mice. PMID:21439349

  17. Amps particle accelerator definition study

    Sellen, J. M., Jr.

    1975-01-01

    The Particle Accelerator System of the AMPS (Atmospheric, Magnetospheric, and Plasmas in Space) payload is a series of charged particle accelerators to be flown with the Space Transportation System Shuttle on Spacelab missions. In the configuration presented, the total particle accelerator system consists of an energetic electron beam, an energetic ion accelerator, and both low voltage and high voltage plasma acceleration devices. The Orbiter is illustrated with such a particle accelerator system.

  18. Accelerator research studies. Progress report

    The major goal of this project is to study the effects that lead to emittance growth and limitation of beam current and brightness in periodic focusing systems (including linear accelerators). This problem is of great importance for all accelerator applications requiring high intensity beams with small emittance such as heavy ion fusion, spallation neutron sources and high energy physics. In the latter case, future machines must not only provide higher energies (in the range of 10 to 100 TeV), but also higher luminosities than the existing facilities. This implies considerably higher phase-space density of the particle beam produced by the injector linac, i.e., the detrimental emittance growth and concurrent beam loss observed in existing linacs must be avoided

  19. Studies of accelerated compact toruses

    In an earlier publication we considered acceleration of plasma rings (Compact Torus). Several possible accelerator configurations were suggested and the possibility of focusing the accelerated rings was discussed. In this paper we consider one scheme, acceleration of a ring between coaxial electrodes by a B/sub theta/ field as in a coaxial rail-gun. If the electrodes are conical, a ring accelerated towards the apex of the cone undergoes self-similar compression (focusing) during acceleration. Because the allowable acceleration force, F/sub a/ = kappaU/sub m//R where (kappa -2, the accelerating distance for conical electrodes is considerably shortened over that required for coaxial electrodes. In either case, however, since the accelerating flux can expand as the ring moves, most of the accelerating field energy can be converted into kinetic energy of the ring leading to high efficiency

  20. Optimal Design of Multiple Stresses Accelerated Life Test Plan Based on Transforming the Multiple Stresses to Single Stress

    GAO Liang; CHEN Wenhua; QIAN Ping; PAN Jun; HE Qingchuan

    2014-01-01

    For planning optimum multiple stresses accelerated life test plans, a commonly followed guiding principle is that all parameters of the life-stress relationship should be estimated, and the number of the stress level combinations must be no less than the number of parameters of the life-stress relationship. However, the general objective of an accelerated life test(ALT) is to assess thep-th quantile of the product life distribution under normal stress. For this objective,estimating all model parameters is not necessary, and this will increase the cost of test. Based on the theoretical conclusion that the stress level combinations of the optimum multiple stresses ALT plan locate on a straight line through the origin of coordinate, it is proposed that a design idea of planning the optimum multiple stresses ALT plan through transforming the problem of designing an optimum multiple stresses ALT plan to designing an optimum single stress ALT plan. Moreover, a method of planning the optimum multiple stresses ALT plan which can avoid estimating all model parameters is established. An example shows that, the proposed plan which only has two stress level combinations could achieve an accuracy no less than the traditional plan, and save the test time and cost on one stress level combination at least; when the actual product life is less than the design value, even the deviation of the model initial parameters value is up to 20%, the variance of the estimation of thep-th quantile of the proposed plan is still smaller than the traditional plans approximately 25%. A design method is provided for planning the optimum multiple stresses ALT which uses the statistical optimum degenerate test plan as the optimum multiple stresses accelerated life test plan.

  1. Flow accelerated corrosion study in feeder pipes

    Goyal, P.; Verma, V.; Singh, R.K. [Bhabha Atomic Research Centre, Mumbai (India). Reactor Safety Div.

    2014-11-15

    The Indian Pressurized Heavy Water Reactor (PHWR) core consists of a number of horizontal channels containing nuclear fuel bundles. Parallel coolant channels are connected to Inlet and Outlet header through feeder pipes. Coolant from Reactor Inlet Header is distributed to the coolant channels and after removing heat combines at Reactor Outlet Header. Due to space constraints the feeder pipes are joined to the channel with one or two elbows close to the end fittings of the coolant channels. The carbon steel feeder pipes carry high temperature fluid at higher velocity and are liable to undergo Flow Accelerated Corrosion (FAC). In the recent inspection it has been found that feeders having double elbow are more susceptible to FAC on the intrados of second elbow. But it was found that in some of the elbows maximum thinning due to FAC was observed on the intrados of the first elbow. Hence to resolve this, effect of first bend orientation with respect of upstream direction has been studied. Two different approaches are used for predicting the FAC rate from calculated value of wall shear stress by CFD. One method is based on evaluating of wear rate using Colburn analogy and the other using an empirical equation between wear rate and shear stress. In Colburn analogy, mass transfer coefficient is evaluated by knowing shear stress and equilibrium concentration. For a case study, wall shear stress obtained from k-ε turbulence model was compared with k-ω SST turbulence model and no appreciable change in the wall shear stress has been found. Hence for subsequent analysis k-ε turbulence model was chosen because large mesh size near to the surface (first layer thickness) is permitted due to higher y{sup +} value.

  2. Constant-stress partially accelerated life tests for inverted Weibull distribution with multiple censored data

    Amal S. Hassan

    2015-04-01

    Full Text Available Testing the lifetime of items under normal use condition often requires a long period of time, especially for products having high reliability. To minimize the costs involved in testing without reducing the quality of the data obtained, the items run at higher than usual level of stresses to induce early failures in a short time. This article concerns with constant–stress partially accelerated life test with multiple censored data. The life time of test item is assumed to follow inverted Weibull distribution. Maximum likelihood estimates are obtained for the model parameters and acceleration factor. In addition, asymptotic variance and covariance matrix of the estimators is given. The confidence intervals of the unknown parameters and acceleration factor are constructed for large sample sizes. Simulation studies are performed to investigate the performance of the estimators.

  3. Step-Stress Accelerated Degradation Testing for Solar Reflectors: Preprint

    Jones, W.; Elmore, R.; Lee, J.; Kennedy, C.

    2011-09-01

    To meet the challenge to reduce the cost of electricity generated with concentrating solar power (CSP) new low-cost reflector materials are being developed including metalized polymer reflectors and must be tested and validated against appropriate failure mechanisms. We explore the application of testing methods and statistical inference techniques for quantifying estimates and improving lifetimes of concentrating solar power (CSP) reflectors associated with failure mechanisms initiated by exposure to the ultraviolet (UV) part of the solar spectrum. In general, a suite of durability and reliability tests are available for testing a variety of failure mechanisms where the results of a set are required to understand overall lifetime of a CSP reflector. We will focus on the use of the Ultra-Accelerated Weathering System (UAWS) as a testing device for assessing various degradation patterns attributable to accelerated UV exposure. Depending on number of samples, test conditions, degradation and failure patterns, test results may be used to derive insight into failure mechanisms, associated physical parameters, lifetimes and uncertainties. In the most complicated case warranting advanced planning and statistical inference, step-stress accelerated degradation (SSADT) methods may be applied.

  4. Increased rate of acceleration on Pine Island Glacier strongly coupled to changes in gravitational driving stress

    J. B. T. Scott

    2009-05-01

    Full Text Available Pine Island Glacier, Antarctica, has been undergoing several related changes for at least two decades; these include acceleration, thinning and grounding line retreat. During the first major ground-based study between 2006 and 2008, GPS receivers were used to monitor ice flow from 55 km to 171 km inland, along the central flowline. At four sites both acceleration and thinning rates over the last two years exceeded rates observed at any other time over the last two decades. At the downstream site acceleration was 6.4% over 2007 and thinning was 3.5±0.5 ma−1. Acceleration and thinning have spread rapidly inland with the acceleration 171 km inland at 4.1% over 2007, greater than any measured annual flow increase along the whole glacier prior to 2006. Increases in surface slope, and hence gravitational driving stress, correlate well with the acceleration and no sustained change in longitudinal stress gradient is needed to explain the force balance. There is no indication that the glacier is approaching a new steady state.

  5. Status of the Fatigue Studies on the CLIC Accelerating Structures

    Calatroni, S; Neupert, H; Wuensch, Walter; CERN. Geneva

    2006-01-01

    The need for high accelerating gradients for the future multi-TeV e+e- Compact Linear Collider (CLIC) imposes considerable constraints on the materials of the accelerating structures. The surfaces exposed to high pulsed RF (Radio Frequency) currents are subject to cyclic thermal stresses which are expected to induce surface break up by fatigue. Since no fatigue data exists in the literature up to very large numbers of cycles and for the particular stress pattern present in RF cavities, a comprehensive study of copper alloys in this parameter range has been initiated. Fatigue data for selected copper alloys in different states are presented

  6. Accelerated versus traditional nursing students: a comparison of stress, critical thinking ability and performance.

    Yousseff, F A; Goodrich, N

    1996-02-01

    A high demand for graduate nurses and a dwindling pool of nursing school applicants have led several collegiate nursing programs to adopt innovative programs to increase the number of eligible applicants. One option is the development of accelerated nursing program. Because of the relative newness of these programs, the need to ascertain data about accelerated students and their success in these programs is vital. This prospective study examines the differences in stress levels, critical thinking ability, and performance of traditional and accelerated nursing students. A voluntary convenient sample (n = 94) was used from nursing students enrolled in the Associate Degree Nursing (ADN) program. The State-Trait Anxiety Inventory and the Scale of Judgmental Abilities were used to measure the two independent variables. The grade point average in nursing courses and the National Council Licensure Exam scores were employed to measure performance of students. Results revealed that accelerated students showed consistently higher stress levels than those of the traditional students. Moreover, the accelerated group had significantly higher grade averages in nursing courses than traditional students. Implications for nurse educators and recommendations for further studies were made. PMID:8655267

  7. Accelerated stress testing of amorphous silicon solar cells

    Stoddard, W. G.; Davis, C. W.; Lathrop, J. W.

    1985-01-01

    A technique for performing accelerated stress tests of large-area thin a-Si solar cells is presented. A computer-controlled short-interval test system employing low-cost ac-powered ELH illumination and a simulated a-Si reference cell (seven individually bandpass-filtered zero-biased crystalline PIN photodiodes) calibrated to the response of an a-Si control cell is described and illustrated with flow diagrams, drawings, and graphs. Preliminary results indicate that while most tests of a program developed for c-Si cells are applicable to a-Si cells, spurious degradation may appear in a-Si cells tested at temperatures above 130 C.

  8. Step-Stress Accelerated Degradation Testing (SSADT) for Photovoltaic (PV) Devices and Cells (Presentation)

    Lee, J.; Elmore, R.; Suh, C.; Jones, W.

    2010-10-01

    Presentation on step-stress accelerated degradation testing (SSADT) for photovoltaics (PV). Developed are a step-stress degradation test (SSADT) for PV reliability tests and a lifetime prediction model for PV products.

  9. STATISTICAL INFERENCE OF WEIBULL DISTRIBUTION FOR TAMPERED FAILURE RATE MODEL IN PROGRESSIVE STRESS ACCELERATED LIFE TESTING

    WANG Ronghua; FEI Heliang

    2004-01-01

    In this note, the tampered failure rate model is generalized from the step-stress accelerated life testing setting to the progressive stress accelerated life testing for the first time. For the parametric setting where the scale parameter satisfying the equation of the inverse power law is Weibull, maximum likelihood estimation is investigated.

  10. Accelerator research studies: Annual technical report

    This paper discusses accelerator research at the University of Maryland. The three task studies contained in this paper are: Instabilities and Emittance Growth in Periodic Focusing Systems for Intense Beams; Collective Ion Acceleration by Intense Electron Beams and Pulse Powered Plasma Focus; and Microwave Sources and Parameter Scaling for High-Frequency e+e/sup /minus// Supercollider Linacs

  11. Report on accelerated corrosion studies.

    Mowry, Curtis Dale; Glass, Sarah Jill; Sorensen, Neil Robert

    2011-03-01

    Sandia National Laboratories (SNL) conducted accelerated atmospheric corrosion testing for the U.S. Consumer Product Safety Commission (CPSC) to help further the understanding of the development of corrosion products on conductor materials in household electrical components exposed to environmental conditions representative of homes constructed with problem drywall. The conditions of the accelerated testing were chosen to produce corrosion product growth that would be consistent with long-term exposure to environments containing humidity and parts per billion (ppb) levels of hydrogen sulfide (H{sub 2}S) that are thought to have been the source of corrosion in electrical components from affected homes. This report documents the test set-up, monitoring of electrical performance of powered electrical components during the exposure, and the materials characterization conducted on wires, screws, and contact plates from selected electrical components. No degradation in electrical performance (measured via voltage drop) was measured during the course of the 8-week exposure, which was approximately equivalent to 40 years of exposure in a light industrial environment. Analyses show that corrosion products consisting of various phases of copper sulfide, copper sulfate, and copper oxide are found on exposed surfaces of the conductor materials including wires, screws, and contact plates. The morphology and the thickness of the corrosion products showed a range of character. In some of the copper wires that were observed, corrosion product had flaked or spalled off the surface, exposing fresh metal to the reaction with the contaminant gasses; however, there was no significant change in the wire cross-sectional area.

  12. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling

    Zannas, A.; Arloth, J.; Carrillo Roa, T.; Iurato, S.; Roeh, S.; Ressler, K; Nemeroff, C.; Smith, A.; Bradley, B; Heim, C; Menke, A.; Lange, J; Brueckl, T.; Ising, M; Wray, N.

    2015-01-01

    Background Chronic psychological stress is associated with accelerated aging and increased risk for aging-related diseases, but the underlying molecular mechanisms are unclear. Results We examined the effect of lifetime stressors on a DNA methylation-based age predictor, epigenetic clock. After controlling for blood cell-type composition and lifestyle parameters, cumulative lifetime stress, but not childhood maltreatment or current stress alone, predicted accelerated epigenetic aging in an ur...

  13. Stress studies in EFG

    1984-01-01

    Electrical characterization of defects induced in FZ and CZ silicon stress in four-point bending above 1200 C was started. Techniques to study electrical activity that will permit correlation of defect activity with diffusion length and with room and low temperature EBIC are being developed. Preliminary characterization of defects in ribbon grown at very low speeds of less than 1 cm/min shows that the dislocation density is very low over significant regions of cross section, while regions of high dislocation density (approx. 5 x 10(6)/cm(2)) occur in bands in a number of places. Addition measurements of stress distributions in EFG material were obtained at the University of Illinois using shadow-Moire interferometry.

  14. Accelerated fat cell aging links oxidative stress and insulin resistance in adipocytes

    Finny Monickaraj; Sankaramoorthy Aravind; Pichamoorthy Nandhini; Paramasivam Prabu; Chandrakumar Sathishkumar; Viswanathan Mohan; Muthuswamy Balasubramanyam

    2013-03-01

    Telomere shortening is emerging as a biological indicator of accelerated aging and aging-related diseases including type 2 diabetes. While telomere length measurements were largely done in white blood cells, there is lack of studies on telomere length in relation to oxidative stress in target tissues affected in diabetes. Therefore, the aim of this study is to induct oxidative stress in adipocytes and to test whether these adipocytes exhibit shortened telomeres, senescence and functional impairment. 3T3-L1 adipocytes were subjected to oxidative stress and senescence induction by a variety of means for 2 weeks (exogenous application of H2O2, glucose oxidase, asymmetric dimethylarginine (ADMA) and glucose oscillations). Cells were probed for reactive oxygen species generation (ROS), DNA damage, mRNA and protein expression of senescent and pro-inflammatory markers, telomere length and glucose uptake. Compared to untreated cells, both ROS generation and DNA damage were significantly higher in cells subjected to oxidative stress and senescence. Adipocytes subjected to oxidative stress also showed shortened telomeres and increased mRNA and protein expression of p53, p21, TNF and IL-6. Senescent cells were also characterized by decreased levels of adiponectin and impaired glucose uptake. Briefly, adipocytes under oxidative stress exhibited increased ROS generation, DNA damage, shortened telomeres and switched to senescent/pro-inflammatory phenotype with impaired glucose uptake.

  15. A specific group of genes respond to cold dehydration stress in cut Alstroemeria flowers whereas ambient dehydration stress accelerates developmental senescence expression patterns.

    Wagstaff, Carol; Bramke, Irene; Breeze, Emily; Thornber, Sarah; Harrison, Elizabeth; Thomas, Brian; Buchanan-Wollaston, Vicky; Stead, Tony; Rogers, Hilary

    2010-06-01

    Petal development and senescence entails a normally irreversible process. It starts with petal expansion and pigment production, and ends with nutrient remobilization and ultimately cell death. In many species this is accompanied by petal abscission. Post-harvest stress is an important factor in limiting petal longevity in cut flowers and accelerates some of the processes of senescence such as petal wilting and abscission. However, some of the effects of moderate stress in young flowers are reversible with appropriate treatments. Transcriptomic studies have shown that distinct gene sets are expressed during petal development and senescence. Despite this, the overlap in gene expression between developmental and stress-induced senescence in petals has not been fully investigated in any species. Here a custom-made cDNA microarray from Alstroemeria petals was used to investigate the overlap in gene expression between developmental changes (bud to first sign of senescence) and typical post-harvest stress treatments. Young flowers were stressed by cold or ambient temperatures without water followed by a recovery and rehydration period. Stressed flowers were still at the bud stage after stress treatments. Microarray analysis showed that ambient dehydration stress accelerates many of the changes in gene expression patterns that would normally occur during developmental senescence. However, a higher proportion of gene expression changes in response to cold stress were specific to this stimulus and not senescence related. The expression of 21 transcription factors was characterized, showing that overlapping sets of regulatory genes are activated during developmental senescence and by different stresses. PMID:20457576

  16. Behavioral stress accelerates prostate cancer development in mice

    Hassan, Sazzad; Karpova, Yelena; Baiz, Daniele; Yancey, Dana; Pullikuth, Ashok; Flores, Anabel; Register, Thomas; Cline, J. Mark; D’Agostino, Ralph; Danial, Nika; Datta, Sandeep Robert; Kulik, George

    2013-01-01

    Prostate cancer patients have increased levels of stress and anxiety. Conversely, men who take beta blockers, which interfere with signaling from the stress hormones adrenaline and noradrenaline, have a lower incidence of prostate cancer; however, the mechanisms underlying stress–prostate cancer interactions are unknown. Here, we report that stress promotes prostate carcinogenesis in mice in an adrenaline-dependent manner. Behavioral stress inhibited apoptosis and delayed prostate tumor invol...

  17. Heating of the fuel mixture due to viscous stress ahead of accelerating flames in deflagration-to-detonation transition

    Valiev, Damir; Bychkov, Vitaly; Akkerman, V'yacheslav; Eriksson, Lars-Erik; Marklund, Mattias

    2008-01-01

    The role of viscous stress in heating of the fuel mixture in deflagration-to-detonation transition in tubes is studied both analytically and numerically. The analytical theory is developed in the limit of low Mach number; it determines temperature distribution ahead of an accelerating flame with maximum achieved at the walls. The heating effects of viscous stress and the compression wave become comparable at sufficiently high values of the Mach number. In the case of relatively large Mach num...

  18. Radiative processes for Rindler and accelerating observers and the stress-tensor detector

    De Paola, R

    1996-01-01

    We consider a monopole detector interacting with a massive scalar field. The radiative processes are discussed from the accelerated frame point of view. After this, we obtain the Minkowski vacuum stress tensor measured by the accelerated observer using a non-gravitational stress tensor detector as discussed by Ford and Roman (PRD 48, 776 (1993)). Finally, we analyse radiative processes of the monopole detector travelling in a world line that is inertial in the infinite past and has a constant proper acceleration in the infinite future.

  19. Stress and efficiency studies

    1985-01-01

    Optical and electrical characterization of defects has been started in EFG ribbon grown in a system that will be used to test the stress model. Temperature and stress field modeling aimed at defining low stress growth configuration is also in progress, and results will be used to guide development of the experimental system. The baseline defect configuration for ribbon grown at speeds of approx. 1 cm/min consists of dislocation densities of the order of 10 to the 5th power to 10 to the 6th power/sq cm, as well as saucer type etch pits and line defects. All these defects are inhomogeneously distributed. EBIC measurements indicate that diffusion lengths are in the range 20 to 60 microns, and significant spatial inhomogeneities occur through the ribbon thickness. Growth speed changes in the range 0.7-1.0 cm/min do not produce significant variations in ribbon defect configurations.

  20. W-band accelerator study in KEK

    Zhu, Xiongwei; Nakajima, Kazuhisa

    2001-05-01

    In this paper, we summarize the W-band accelerator study in KEK. We present a design study on W-Band photocathode RF gun which is capable of generating and accelerating 300 pC electron bunch. The design system is made up of 91.392 GHz photocathode RF gun and 91.392 GHz traveling wave linac cells. Based on the numerical simulation using SUPERFISH and PARMELA and the conventional RF linac scaling law, the design will produce 300 pC at 1.74 MeV with bunch length 0.72 ps and normalized transverse emittance 0.55 mm mrad. We study the beam dynamics in high frequency and high gradient; due to the high gradient, the pondermotive effect plays an important role in beam dynamics; we found the pondermotive effect still exist with only the fundamental space harmonics (synchrotron mode) due to the coupling of the transverse and longitudinal motion.

  1. Temperature and thermal stresses in accelerator target plates

    Simple calculations of temperatures and elastic thermal stresses are given for a particular design of spallation neutron target plate in normal operation and in a quench process used in its manufacture. The main conclusion is that considerable plastic deformation will occur in both circumstances. (author)

  2. Investigation of reliability attributes and accelerated stress factors of terrestrial solar cells. Second annual report

    Lathrop, J.W.; Prince, J.L.

    1980-04-01

    The work covered in this report represents the second year's effort of a continuing program to determine the reliability attributes of terrestrial solar cells. Three main tasks were undertaken during the reporting period: (1) a study of the electrical behavior of cells in the second (reverse) quadrant, (2) the accelerated stress testing of three new state of the art cells and (3) the continued bias-temperature testing of four Block II type silicon cells at 78/sup 0/C and 135/sup 0/C. Electrical characteristics measured in the second quadrant were determined to be a function of the cell's thermal behavior with breakdown depending on the initiation of localized heating. This implied that high breakdown cells may be more fault tolerant when forced to operate in the second quadrant - a result contrary to conventional thinking. The accelerated stress tests used in the first (power) quadrant were bias-temperature, bias-temperature-humidity, temperature-humidity, thermal shock, and thermal cycle. The new type cells measured included an EFG cell, a polycrystalline cell, and a Czochralski cell. Electrical parameters measured included I/sub SC/, V/sub OC/, P/sub M/, and I/sub M/. Incorporated in the report are the distributions of prestress electrical data for all cell types. Significant differences in the response to the various stress tests were observed between cell types. A microprocessed controlled, short interval solar cell tester was designed and construction initiated on a prototype for use in the program.

  3. Accelerator physics studies for the SSC

    In the spring of 1984, a reference designs study (RDS) was carried out to identify the issues and to provide a crude cost estimate of the SSC. Following the RDS, a Central Design Group was formed in October to perform the detailed design RandD for construction of the SSC. This paper is a brief review of progress made on the accelerator physics studies since October 1984. For major issues not discussed here, many of them of great importance, the RDS report is still the valid source of information

  4. Constant-stress partially accelerated life tests for inverted Weibull distribution with multiple censored data

    Amal S. Hassan; Salwa M. Assar; Ahmed N. Zaky

    2015-01-01

    Testing the lifetime of items under normal use condition often requires a long period of time, especially for products having high reliability. To minimize the costs involved in testing without reducing the quality of the data obtained, the items run at higher than usual level of stresses to induce early failures in a short time. This article concerns with constant–stress partially accelerated life test with multiple censored data. The life time of test item is assumed to follow inverted Weib...

  5. Studies on HF quadrupole accelerator structures

    The present thesis had the aim to elaborate advantages and disadvantages of existing high frequency resonators in the MHz range regarding their use as RFQ power supply structures and to limit their application ranges. After a short survey over potential and field distributions in the RFQ suitable criteria for the valuation of RFQ resonators are indicated. For the experimentally studied resonators equivalent circuits are presented, in some cases these are theoretically analyzed. Finally the construction of the GSI/Frankfurt proton model as well experiments with the accelerated proton beams are described. (orig.)

  6. MAFIA study of the RFQ1 accelerator

    Adams, F. P.; de Jong, M. S.; Hutcheon, R. M.

    1991-05-01

    The RFQ1 accelerator has been modeled using the MAFIA codes. Calculated resonant frequency shifts due to the introduction of components into the accelerator agree reasonably well with measurements. Heating predictions based on calculated results correspond well with observations.

  7. Vacuum studies for the Vivitron accelerator

    Experimental measurements have been conducted for an accelerating tube section and for the vacuum pressure running conditions in the Strasbourg MP accelerating tube. Based on the deduced parameters, on the proposed terminal stripping arrangement and tube pumping system for the Vivitron, the vacuum pressure distribution has been determined along the accelerating tube

  8. Quantum corrections to the stress-energy tensor in thermodynamic equilibrium with acceleration

    Becattini, F.; Grossi, E.

    2015-08-01

    We show that the stress-energy tensor has additional terms with respect to the ideal form in states of global thermodynamic equilibrium in flat spacetime with nonvanishing acceleration and vorticity. These corrections are of quantum origin and their leading terms are second order in the gradients of the thermodynamic fields. Their relevant coefficients can be expressed in terms of correlators of the stress-energy tensor operator and the generators of the Lorentz group. With respect to previous assessments, we find that there are more second-order coefficients and that all thermodynamic functions including energy density receive acceleration and vorticity dependent corrections. Notably, also the relation between ρ and p , that is, the equation of state, is affected by acceleration and vorticity. We have calculated the corrections for a free real scalar field—both massive and massless—and we have found that they increase, particularly for a massive field, at very high acceleration and vorticity and very low temperature. Finally, these nonideal terms depend on the explicit form of the stress-energy operator, implying that different stress-energy tensors of the scalar field—canonical or improved—are thermodynamically inequivalent.

  9. Accelerated Aging during Chronic Oxidative Stress: A Role for PARP-1

    Daniëlle M. P. H. J. Boesten

    2013-01-01

    Full Text Available Oxidative stress plays a major role in the pathophysiology of chronic inflammatory disease and it has also been linked to accelerated telomere shortening. Telomeres are specialized structures at the ends of linear chromosomes that protect these ends from degradation and fusion. Telomeres shorten with each cell division eventually leading to cellular senescence. Research has shown that poly(ADP-ribose polymerase-1 (PARP-1 and subtelomeric methylation play a role in telomere stability. We hypothesized that PARP-1 plays a role in accelerated aging in chronic inflammatory diseases due to its role as coactivator of NF-κb and AP-1. Therefore we evaluated the effect of chronic PARP-1 inhibition (by fisetin and minocycline in human fibroblasts (HF cultured under normal conditions and under conditions of chronic oxidative stress, induced by tert-butyl hydroperoxide (t-BHP. Results showed that PARP-1 inhibition under normal culturing conditions accelerated the rate of telomere shortening. However, under conditions of chronic oxidative stress, PARP-1 inhibition did not show accelerated telomere shortening. We also observed a strong correlation between telomere length and subtelomeric methylation status of HF cells. We conclude that chronic PARP-1 inhibition appears to be beneficial in conditions of chronic oxidative stress but may be detrimental under relatively normal conditions.

  10. Study of Tandem Accelerator Technology and Its Prospects

    Tandem accelerator is an ion acceleration tool in which negative ions injected in the accelerator tube and stripped to become positive ions, then accelerated by electrostatic high voltage such that its energy is multiplied. In this paper, we describe the prospect of accelerator application briefly in agriculture and biotechnology, industry, health and medicine, environment fields. Technical study on tandem accelerator included SNICS and alphatross ion sources, acceleration system and stripper system. The study result for many kinds of negative ions and its current which should be injected in the accelerator tube and the output of tandem accelerator H+, and the distribution of C+, Ni+, Au+, Br+ ion on varying charge state is shown. (author)

  11. Residual stress measurements of U-bends and correlation with accelerated stress corrosion tests

    Various experimental techniques have been used to determine the residual stresses in U-bends of steam generator tubing. These include x-ray diffraction, strain gage sectioning, and strain gage sectioning with layer removal. The relative merits of each are discussed and the results from several investigations are presented. There is a large variability, even for a given technique, but most residual stress values are compressive or low tension implying little concern for stress corrosion cracking due to fabrication

  12. International Society for Traumatic Stress Studies

    ... Traumatic Stress Studies Log In Search for: International Society for Traumatic Stress Studies Assessing Trauma Acute Stress ... effects of severe psychological trauma on individuals and society. http://www.listeningtotrauma.org/ view full calendar Join ...

  13. Theoretical and experimental studies of a plasma- and particle accelerator

    Using the combination of a coaxial plasma accelerator with a compression coil a dense and fast plasma flow can be produced and applied for gas-dynamical acceleration of particles. The theoretical and experimental studies presented here contribute to a better understanding of the acceleration process and to the operational application of the system as a micrometeor simulator. (orig.)

  14. Accelerator

    The invention claims equipment for stabilizing the position of the front covers of the accelerator chamber in cyclic accelerators which significantly increases accelerator reliability. For stabilizing, it uses hydraulic cushions placed between the electromagnet pole pieces and the front chamber covers. The top and the bottom cushions are hydraulically connected. The cushions are disconnected and removed from the hydraulic line using valves. (J.P.)

  15. Chronic stress accelerates ligature-induced periodontitis by suppressing glucocorticoid receptor-α signaling

    Lu, Huaixiu; Xu, Minguang; Wang, Feng; Liu, Shisen; Gu, Jing; Lin, Songshan; Zhao, Lisheng

    2016-01-01

    Periodontitis is a common chronic inflammatory disease. Recent studies have shown that chronic stress (CS) might modulate periodontal disease, but there are few models of CS-induced periodontitis, and the underlying mechanisms are unclear. The present study established a rat model of periodontitis associated with CS induced by nylon thread ligatures. The severity of periodontitis was evaluated in this model by radiographic and pathological examination. The inflammatory reaction indicated by the elevated serum levels of interleukin (IL)-1β, IL-6 and IL-8 was assessed by enzyme-linked immunosorbent assay. Toll-like receptor-4 (TLR4) and glucocorticoid receptor-α (GR-α) expressions were detected by reverse transcriptase-PCR and western blotting. Open-field tests and serum corticosterone were used to evaluate CS. The results showed that CS induced behavioral changes and increased corticosterone levels of the animals with periodontitis. CS stimulation markedly increased alveolar bone loss, periodontal pocket depth and the number of plaques. It also enhanced the inflammatory reaction. These results suggest that CS accelerated the ligature-induced pathological changes associated with periodontitis. Further analysis of the mechanisms involved showed that GR-α expression was significantly downregulated in periodontal tissues of the animals undergoing CS. Blocking GR-α signaling in lipopolysaccharide and corticosteroid-treated human periodontal ligament fibroblast cells in vitro significantly upregulated the expression of p-Akt (protein kinase B) and TLR4, promoted nuclear factor-κB activity and increased levels of IL-1β, IL-6 and IL-8. This research suggests that CS might accelerate the pathological progression of periodontitis by a GR-α signaling-mediated inflammatory response and that this may be a potential therapeutic target for the treatment of periodontal disease, particularly in patients with CS. PMID:27012709

  16. ESTIMATION OF PARAMETERS IN STEP-STRESS ACCELERATED LIFE TESTS FOR THE RAYLEIGH DISTRIBUTION UNDER CENSORING SETUP

    N. Chandra

    2014-12-01

    Full Text Available In this paper, step-stress accelerated life test strategy is considered in obtaining the failure time data of the highly reliable items or units or equipment in a specified period of time. It is assumed that life time data of such items follows a Rayleigh distribution with a scale parameter (θ which is the log linear function of the stress levels. The maximum likelihood estimates (MLEs of the scale parameters ( i θ at both the stress levels (s , i = 2,1 i are obtained under a cumulative exposure model. A simulation study is performed to assess the precision of the MLEs on the basis of mean square error (MSE and relative absolute bias (RABias. The coverage probabilities of approximate and bootstrap confidence intervals for the parameters involved under both the censoring setup are numerically examined. In addition to this, asymptotic variance and covariance matrix of the estimators are also presented.

  17. Heating of the fuel mixture due to viscous stress ahead of accelerating flames in deflagration-to-detonation transition

    Valiev, Damir; Akkerman, V'yacheslav; Eriksson, Lars-Erik; Marklund, Mattias

    2008-01-01

    The role of viscous stress in heating of the fuel mixture in deflagration-to-detonation transition in tubes is studied both analytically and numerically. The analytical theory is developed in the limit of low Mach number; it determines temperature distribution ahead of an accelerating flame with maximum achieved at the walls. The heating effects of viscous stress and the compression wave become comparable at sufficiently high values of the Mach number. In the case of relatively large Mach number, viscous heating is investigated by direct numerical simulations. The simulations were performed on the basis of compressible Navier-Stokes gas-dynamic equations taking into account chemical kinetics. In agreement with the theory, viscous stress makes heating and explosion of the fuel mixture preferential at the walls. The explosion develops in an essentially multi-dimensional way, with fast spontaneous reaction spreading along the walls and pushing inclined shocks. Eventually, the combination of explosive reaction an...

  18. Constant-Step Stress Accelerated Life Test of VFD under Logarithmic Normal Distribution Case

    2006-01-01

    In order to solve the life problem of vacuum fluorescent display (VFD) within shorter time, and reduce the life prediction cost, a constant-step stress accelerated life test was performed with its cathode temperature increased. Statistical analysis was done by applying logarithmic normal distribution for describing the life, and least square method (LSM) for estimating logarithmic normal parameters. Self-designed special software was used to predict the VFD life. It is verified by numerical results that the VFD life follows logarithmic normal distribution,and that the life-stress relationship satisfies linear Arrhenius equation completely. The accurate calculation of the key parameters enables the rapid estimation of VFD life.

  19. Constant-step stress accelerated life test of VFD under Weibull distribution case

    ZHANG Jian-ping; GENG Xin-min

    2005-01-01

    Constant-step stress accelerated life test of Vacuum Fluorescent Display (VFD) was conducted with increased cathode temperature. Statistical analysis was done by applying Weibull distribution for describing the life, and Least Square Method (LSM)for estimating Weibull parameters. Self-designed special software was used to predict the VFD life. Numerical results showed that the average life of VFD is over 30000 h, that the VFD life follows Weibull distribution, and that the life-stress relationship satisfies linear Arrhenius equation completely. Accurate calculation of the key parameter enabled rapid estimation of VFD life.

  20. Studying Radiation Damage in Structural Materials by Using Ion Accelerators

    Hosemann, Peter

    2011-02-01

    Radiation damage in structural materials is of major concern and a limiting factor for a wide range of engineering and scientific applications, including nuclear power production, medical applications, or components for scientific radiation sources. The usefulness of these applications is largely limited by the damage a material can sustain in the extreme environments of radiation, temperature, stress, and fatigue, over long periods of time. Although a wide range of materials has been extensively studied in nuclear reactors and neutron spallation sources since the beginning of the nuclear age, ion beam irradiations using particle accelerators are a more cost-effective alternative to study radiation damage in materials in a rather short period of time, allowing researchers to gain fundamental insights into the damage processes and to estimate the property changes due to irradiation. However, the comparison of results gained from ion beam irradiation, large-scale neutron irradiation, and a variety of experimental setups is not straightforward, and several effects have to be taken into account. It is the intention of this article to introduce the reader to the basic phenomena taking place and to point out the differences between classic reactor irradiations and ion irradiations. It will also provide an assessment of how accelerator-based ion beam irradiation is used today to gain insight into the damage in structural materials for large-scale engineering applications.

  1. Reliability Estimation based on Step-Stress Accelerated Degradation Testing by Unequal Interval Time Series Analysis

    Li Wang; Zaiwen Liu; Chongchong Yu

    2013-01-01

    This paper proposes a reliability estimation method based on Step-Stress Accelerated Degradation Testing (SSADT) data analysis using unequal interval time series analysis. A Multi-Regression Time Varying Auto-Regressive (MRTVAR) degradation time series model is proposed. Product SSADT data are treated as unequal interval composite time series and described using MRTVAR time series model and utilized to predict long-term trend of degradation. By using the suggested method, product reliability ...

  2. Life prediction of OLED for constant-stress accelerated degradation tests using luminance decaying model

    In order to acquire the life information of organic light emitting diode (OLED), three groups of constant stress accelerated degradation tests are performed to obtain the luminance decaying data of samples under the condition that the luminance and the current are respectively selected as the indicator of performance degradation and the test stress. Weibull function is applied to describe the relationship between luminance decaying and time, least square method (LSM) is employed to calculate the shape parameter and scale parameter, and the life prediction of OLED is achieved. The numerical results indicate that the accelerated degradation test and the luminance decaying model reveal the luminance decaying law of OLED. The luminance decaying formula fits the test data very well, and the average error of fitting value compared with the test data is small. Furthermore, the accuracy of the OLED life predicted by luminance decaying model is high, which enable rapid estimation of OLED life and provide significant guidelines to help engineers make decisions in design and manufacturing strategy from the aspect of reliability life. - Highlights: • We gain luminance decaying data by accelerated degradation tests on OLED. • The luminance decaying model objectively reveals the decaying law of OLED luminance. • The least square method (LSM) is employed to calculate Weibull parameters. • The plan designed for accelerated degradation tests proves to be feasible. • The accuracy of the OLED life and the luminance decaying fitting formula is high

  3. Performance Improvisation of Cantilever-type Silicon Micro AccelerationSensors Using Stress Concentration Regions Technique

    B.P. Joshi

    2007-05-01

    Full Text Available Acceleration sensors find applications in missile and competent munitions subsystems.Cantilever-type sensor's sensitivity and bandwidth are dependant on material properties of  thecantilever and structure of proof mass. It is always desired to design a sensor as sensitive aspossible but also maintaining higher bandwidth. In piezoresistive (cantilever-type accelerometers,various techniques were employed by designers to enhance their sensitivity and bandwidth.Most of these techniques are usually focused on shape and size of either cantilever or proofmass. This paper presents a concept of creating stress concentration regions (SCRs on thecantilever for enhancing its sensitivity. Five types of structures were simulated to study thebehaviour of piezoresistive sensors with SCRs implementation. Use of SCRs results in substantialincrease in the sensitivity, which is of the order of 1.85 times the nominal sensitivity. It was aimedat maximising sensor's performance factor, which is the product of sensor bandwidth andsensitivity. This study gives new dimension to the ways of improving performance of cantilever-type inertial piezoresistive sensor.

  4. Accelerator-based studies of intercombination transitions

    Intercombination transitions in multiply-charged few-electron ions have been studied for a number of years now by a number of methods, including beam-foil spectroscopy. Only very recently it has been realized that the intrinsic properties of the beam-foil light source, in particular the time resolution, offer means to single out and measure such transitions from the multiline spectra of many-electron ions where the exploitation of other light sources has been less successful. Wavelengths and transition rates of these lines provide both a test of many-electron atomic theory and tools for plasma diagnostics. As examples, data on Mg-, Al- and Si-like ions of elements Ti-Zn are presented and compared with tokamak, laser-produced plasma and solar flare data. It turns out that the level of adequacy reached by the various theoretical approaches for predictions of wavelengths and transition probabilities in the individual isoelectronic sequences is very different. However, even calculational schemes which are successful for one sequence are much worse for others. The variety of isoelectronic sequences and the ranges of ionic charge for each of the sequences which are accessible at typical heavy-ion accelerator laboratories are outlined in order to encourage the use of existing facilities for this type of spectroscopy. (orig.)

  5. The Study of Expert System Utilization for the Accelerator Operation

    The utilization of expert system in the accelerator laboratory has been studied. The study covers the utilization of expert system in the setting up experiment (tuning parameter), controlling system, safety or warning system. The results study shows, that using the expert system in the accelerator would be easy to operate the accelerator for user and operator. Increasing the skill of expert system could be updated without logical mechanism modification. (author)

  6. Investigation of reliability attributes and accelerated stress factors of terrestrial solar cells. First annual report

    Prince, J.L.; Lathrop, J.W.

    1979-05-01

    The results of accelerated stress testing of four different types of silicon terrestrial solar cells are discussed. The accelerated stress tests used included bias-temperature tests, bias-temperature-humidity tests, thermal cycle and thermal shock tests, and power cycle tests. Characterization of the cells was performed before stress testing and at periodic down-times, using electrical measurement, visual inspection, and metal adherence pull tests. Electrical parameters measured included short-circuit current, I/sub sc/, open circuit voltage, V/sub oc/, and output power, voltage, and current at the maximum power point, P/sub m/, V/sub m/, and I/sub m/ respectively. Incorporated in the report are the distributions of the prestress electrical data for all cell types. Data was also obtained on cell series and shunt resistance. Significant differences in the response to the various stress tests was observed between cell types. On the basis of the experience gained in this research work, a suggested Reliability Qualification Test Schedule was developed.

  7. Computational studies and optimization of wakefield accelerators

    Laser- and particle beam-driven plasma wakefield accelerators produce accelerating fields thousands of times higher than radio-frequency accelerators, offering compactness and ultrafast bunches to extend the frontiers of high energy physics and to enable laboratory-scale radiation sources. Large-scale kinetic simulations provide essential understanding of accelerator physics to advance beam performance and stability and show and predict the physics behind recent demonstration of narrow energy spread bunches. Benchmarking between codes is establishing validity of the models used and, by testing new reduced models, is extending the reach of simulations to cover upcoming meter-scale multi-GeV experiments. This includes new models that exploit Lorentz boosted simulation frames to speed calculations. Simulations of experiments showed that recently demonstrated plasma gradient injection of electrons can be used as an injector to increase beam quality by orders of magnitude. Simulations are now also modeling accelerator stages of tens of GeV, staging of modules, and new positron sources to design next-generation experiments and to use in applications in high energy physics and light sources

  8. Recovery mechanisms in proton exchange membrane fuel cells after accelerated stress tests

    Zhang, Xu; Guo, Liejin; Liu, Hongtan

    2015-11-01

    The mechanisms of performance recovery after accelerated stress test (AST) in proton exchange membrane fuel cells (PEMFCs) are systematically studied. Experiments are carried out by incorporating a well-designed performance recovery procedure right after the AST protocol. The experiment results show that the cell performance recovers significantly from the degraded state after the AST procedure. The results from cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) measurements further show that the performance recovery can be divided into kinetic and mass transport recoveries. It is further determined that the kinetic recovery, i.e. the recovery of electrochemical active area (ECA), is due to two distinct mechanisms: the reduction of platinum oxide and the re-attachment of detached platinum nanoparticles onto the carbon surface. The mass transport resistance is probably due to reduction of hydrophilic oxide groups on the carbon surface and the microstructure change that alleviates flooding. Performance comparisons show that the recovery procedure is highly effective, indicating the results of AST significantly over-estimate the true degradation in a PEM fuel cell. Therefore, a recovery procedure is highly recommended when an AST protocol is used to evaluate cell degradations to avoid over-estimating true performance degradations in PEMFCs.

  9. Lifetime Prediction for Degradation of Solar Mirrors using Step-Stress Accelerated Testing (Presentation)

    Lee, J.; Elmore, R.; Kennedy, C.; Gray, M.; Jones, W.

    2011-09-01

    This research is to illustrate the use of statistical inference techniques in order to quantify the uncertainty surrounding reliability estimates in a step-stress accelerated degradation testing (SSADT) scenario. SSADT can be used when a researcher is faced with a resource-constrained environment, e.g., limits on chamber time or on the number of units to test. We apply the SSADT methodology to a degradation experiment involving concentrated solar power (CSP) mirrors and compare the results to a more traditional multiple accelerated testing paradigm. Specifically, our work includes: (1) designing a durability testing plan for solar mirrors (3M's new improved silvered acrylic "Solar Reflector Film (SFM) 1100") through the ultra-accelerated weathering system (UAWS), (2) defining degradation paths of optical performance based on the SSADT model which is accelerated by high UV-radiant exposure, and (3) developing service lifetime prediction models for solar mirrors using advanced statistical inference. We use the method of least squares to estimate the model parameters and this serves as the basis for the statistical inference in SSADT. Several quantities of interest can be estimated from this procedure, e.g., mean-time-to-failure (MTTF) and warranty time. The methods allow for the estimation of quantities that may be of interest to the domain scientists.

  10. Design of an electromagnetic accelerator for turbulent hydrodynamic mix studies

    Susoeff, A.R.; Hawke, R.S.; Morrison, J.J.; Dimonte, G.; Remington, B.A.

    1993-12-08

    An electromagnetic accelerator in the form of a linear electric motor (LEM) has been designed to achieve controlled acceleration profiles of a carriage containing hydrodynamically unstable fluids for the investigation of the development of turbulent mix. The Rayleigh- Taylor instability is investigated by accelerating two dissimilar density fluids using the LEM to achieve a wide variety of acceleration and deceleration profiles. The acceleration profiles are achieved by independent control of rail and augmentation currents. A variety of acceleration-time profiles are possible including: (1) constant, (2) impulsive and (3) shaped. The LEM and support structure are a robust design in order to withstand high loads with deflections and to mitigate operational vibration. Vibration of the carriage during acceleration could create artifacts in the data which would interfere with the intended study of the Rayleigh-Taylor instability. The design allows clear access for diagnostic techniques such as laser induced fluorescence radiography, shadowgraphs and particle imaging velocimetry. Electromagnetic modeling codes were used to optimize the rail and augmentation coil positions within the support structure framework. Results of contemporary studies for non-arcing sliding contact of solid armatures are used for the design of the driving armature and the dynamic electromagnetic braking system. A 0. 6MJ electrolytic capacitor bank is used for energy storage to drive the LEM. This report will discuss a LEM design which will accelerate masses of up to 3kg to a maximum of about 3000g{sub o}, where g{sub o} is accelerated due to gravity.

  11. Coupler Studies for PBG Fiber Accelerators

    Photonic band gap (PBG) fiber with hollow core defects are being designed and fabricated for use as laser driven accelerators because they can provide gradients of several GeV/m for picosecond pulse lengths. We expect to produce fiber down to λ = 1.5-2.0 (micro)m wavelengths but still lack a viable means for efficient coupling of laser power into such structures due to the very different character of the TM-like modes from those used in the telecom field and the fact that the defect must function as both a longitudinal waveguide for the accelerating field and a transport channel for the particles. We discuss the status of our work in pursuing both end and side coupling. For both options, the symmetry of these crystals leads to significant differences with the telecom field. Side coupling provides more options and appears to be preferred. Our goals are to test gradients, mode content and coupling efficiencies on the NLCTA at SLAC. While there are many potential types of fiber based on very different fabrication methods and materials we will concentrate on 2D axisymmetric glass with hexagonal symmetry but will discuss several different geometries including 2D and 3D planar structures. Since all of these can be fabricated using modern techniques with a variety of dielectric materials they are expected to have desirable optical and radiation hardness properties. Thus, we expect a new generation of very high gradient accelerators that extends the Livingston-Panofsky chart of exponential growth in energy vs. time at greatly reduced costs. For illustration, Fig.1 shows a simulation of our first engineered fiber with an accelerating mode expected near 7.3 (micro)m that is now ready to test on the NLCTA. In this example, one sees the uniform longitudinal accelerating field in the central defect as first shown by Lin3 together with a hexagonal array of surrounding hot spots. Contrary to what one expects from the telecom field, Ng et al. have shown4 that the ideal end

  12. Accelerated Growth Rate and Increased Drought Stress Resilience of the Model Grass Brachypodium distachyon Colonized by Bacillus subtilis B26.

    François Gagné-Bourque

    Full Text Available Plant growth-promoting bacteria (PGB induce positive effects in plants, for instance, increased growth and reduced abiotic stresses susceptibility. The mechanisms by which these bacteria impact the host plant are numerous, diverse and often specific. Here, we studied the agronomical, molecular and biochemical effects of the endophytic PGB Bacillus subtilis B26 on the full life cycle of Brachypodium distachyon Bd21, an established model species for functional genomics in cereal crops and temperate grasses. Inoculation of Brachypodium with B. subtilis strain B26 increased root and shoot weights, accelerated growth rate and seed yield as compared to control plants. B. subtilis strain B26 efficiently colonized the plant and was recovered from roots, stems and blades as well as seeds of Brachypodium, indicating that the bacterium is able to migrate, spread systemically inside the plant, establish itself in the aerial plant tissues and organs, and is vertically transmitted to seeds. The presence of B. subtilis strain B26 in the seed led to systemic colonization of the next generation of Brachypodium plants. Inoculated Brachypodium seedlings and mature plants exposed to acute and chronic drought stress minimized the phenotypic effect of drought compared to plants not harbouring the bacterium. Protection from the inhibitory effects of drought by the bacterium was linked to upregulation of the drought-response genes, DREB2B-like, DHN3-like and LEA-14-A-like and modulation of the DNA methylation genes, MET1B-like, CMT3-like and DRM2-like, that regulate the process. Additionally, total soluble sugars and starch contents increased in stressed inoculated plants, a biochemical indication of drought tolerance. In conclusion, we show a single inoculation of Brachypodium with a PGB affected the whole growth cycle of the plant, accelerating its growth rates, shortening its vegetative period, and alleviating drought stress effects. These effects are relevant to

  13. Parametric study of emerging high power accelerator applications using Accelerator Systems Model (ASM)

    Emerging applications for high power rf linacs include fusion materials testing, generation of intense spallation neutrons for neutron physics and materials studies, production of nuclear materials and destruction of nuclear waste. Each requires the selection of an optimal configuration and operating parameters for its accelerator, rf power system and other supporting subsystems. Because of the high cost associated with these facilities, economic considerations become paramount, dictating a full evaluation of the electrical and rf performance, system reliability/availability, and capital, operating, and life cycle costs. The Accelerator Systems Model (ASM), expanded and modified by Northrop Grumman during 1993-96, provides a unique capability for detailed layout and evaluation of a wide variety of normal and superconducting accelerator and rf power configurations. This paper will discuss the current capabilities of ASM, including the available models and data base, and types of trade studies that can be performed for the above applications. (author)

  14. Cooling the APS storage ring radio-frequency accelerating cavities: Thermal/stress/fatigue analysis and cavity cooling configuration

    The 7-GeV Advanced Photon Source positron storage ring requires sixteen separate 352-MHz radio-frequency (rf) accelerating cavities. Cavities are installed as groups of four, in straight sections used elsewhere for insertion devices. They occupy the first such straight section after injection, along with the last three just before injection. Cooling is provided by a subsystem of the sitewide deionized water system. Pumping equipment is located in a building directly adjacent to the accelerator enclosure. A prototype cavity was fabricated and tested where cooling was via twelve 19-mm-diameter [3/4 in] brazed-on tubes in a series-parallel flow configuration. Unfortunately, the thermal contact to some tubes was poor due to inadequate braze filler. Here, heat transfer studies, including finite-element analysis and test results, of the Advanced Photon Source (APS) storage ring 352-MHz rf accelerating cavities are described. Stress and fatigue life of the copper are discussed. Configuration of water cooling is presented

  15. Cardiovascular studies in the rhesus monkey. [brain circulation during stress

    Stone, H. L.; Sandler, H.

    1977-01-01

    Criteria are given for selecting the macaca mulatta as the analogue of the human in the study of cerebral circulation, particularly the control of the cerebral vascular bed during normal and stressful conditions. Topics discussed include surgical preparation of subject; responses to changes in arterial pressure, oxygen, and carbon dioxide; innervation of cerebral vessels; cerebral flow response to acceleration; and cerebral blood flow and cerebellar stimulation.

  16. Studies on mechanisms of the laser particle acceleration

    Within the last decade, many developments towards higher energies and particle numbers paved the way of particle acceleration performed by high intensity laser systems. Up to now, the process of a field-induced acceleration process (Target-Normal-Sheath-Acceleration (TNSA)) is investigated the most. Acceleration occurs as a consequence of separation of charges on a surface potential. Here, the broad energy spectrum is a problem not yet overcome although many improvements were achieved. Calculations for intensities higher than 1020..21 W/cm2 give hint that Radiation-Pressure-Acceleration (RPA) may lead to a sharper, monoenergetic energy spectrum. Within the framework of this thesis, the investigation of the acceleration mechanism is studied experimentally in the intensity range of 1019 W/cm2. Suitable targets were developed and applied for patent. A broad range of parameters was scanned by means of high repetition rates together with an adequate laser system to provide high statistics of several thousands of shots, and the dependence of target material, intensity, laser polarisation and pre plasma-conditions was verified. Comparisons with 2-d numeric simulations lead to a model of the acceleration process which was analyzed by several diagnostic methods, giving clear evidence for a new, not field-induced acceleration process. In addition, a system for a continuous variation of the polarization based on reflective optics was developed in order to overcome the disadvantages of retardation plates, and their practicability of high laser energies can be achieved.

  17. The senescence-accelerated mouse (SAM): a higher oxidative stress and age-dependent degenerative diseases model.

    Chiba, Yoichi; Shimada, Atsuyoshi; Kumagai, Naoko; Yoshikawa, Keisuke; Ishii, Sanae; Furukawa, Ayako; Takei, Shiro; Sakura, Masaaki; Kawamura, Noriko; Hosokawa, Masanori

    2009-04-01

    The SAM strain of mice is actually a group of related inbred strains consisting of a series of SAMP (accelerated senescence-prone) and SAMR (accelerated senescence-resistant) strains. Compared with the SAMR strains, the SAMP strains show a more accelerated senescence process, a shorter lifespan, and an earlier onset and more rapid progress of age-associated pathological phenotypes similar to human geriatric disorders. The higher oxidative stress status observed in SAMP mice is partly caused by mitochondrial dysfunction, and may be a cause of this senescence acceleration and age-dependent alterations in cell structure and function. Based on our recent observations, we discuss a possible mechanism for mitochondrial dysfunction resulting in the excessive production of reactive oxygen species, and a role for the hyperoxidative stress status in neurodegeneration in SAMP mice. These SAM strains can serve as a useful tool to understand the cellular mechanisms of age-dependent degeneration, and to develop clinical interventions. PMID:18688709

  18. A specific group of genes respond to cold dehydration stress in cut Alstroemeria flowers whereas ambient dehydration stress accelerates developmental senescence expression patterns

    Wagstaff, Carol; Bramke, I.; Breeze, E.; Thornber, S.; Harrison, E; Thomas, B.; Buchanan-Wollaston, V.; Stead, T.; Rogers, H.

    2010-01-01

    Petal development and senescence entails a normally irreversible process. It starts with petal expansion and pigment production, and ends with nutrient remobilization and ultimately cell death. In many species this is accompanied by petal abscission. Post-harvest stress is an important factor in limiting petal longevity in cut flowers and accelerates some of the processes of senescence such as petal wilting and abscission. However, some of the effects of moderate stress in young flowers are r...

  19. Helical flows of second grade fluid due to constantly accelerated shear stresses

    Jamil, M.; Rauf, A.; Fetecau, C.; Khan, N. A.

    2011-04-01

    The helical flows of second grade fluid between two infinite coaxial circular cylinders is considered. The motion is produced by the inner cylinder that at the initial moment applies torsional and longitudinal constantly accelerated shear stresses to the fluid. The exact analytic solutions, obtained by employing the Laplace and finite Hankel transforms and presented in series form in term of usual Bessel functions of first and second kind, satisfy both the governing equations and all imposed initial and boundary conditions. In the limiting case when α → 0, the solutions for Newtonian fluid are obtained for the same motion. The large-time solutions and transient solutions for second grade fluid are also obtained, and effect of material parameter α and kinematic viscosity ν is discussed. In the last, the effects of various parameters of interest on fluid motion as well as the comparison between second grade and Newtonian fluids are analyzed by graphical illustrations.

  20. Accelerated aging of reproductive capacity in male rat offspring of protein-restricted mothers is associated with increased testicular and sperm oxidative stress

    Rodríguez-González, Guadalupe L.; Reyes-Castro, Luis A.; Vega, Claudia C; Boeck, Lourdes; Ibáñez, Carlos; Nathanielsz, Peter W.; Larrea, Fernando; Zambrano, Elena

    2014-01-01

    Maternal protein restriction (MPR) in pregnancy causes life course organ dysfunction, but few studies link the developmental origins of disease hypothesis to early aging. Suboptimal developmental nutrition increases oxidative stress (OS) and male infertility, damaging sperm function. We hypothesized that MPR in pregnancy accelerates age-related changes in testicular and sperm function related to both maternal diet and increased testicular OS in rat offspring. We studied male rats whose pregna...

  1. Investigation of reliability attributes and accelerated stress factors on terrestrial solar cells. Third annual report

    Lathrop, J.W.; Hartman, R.A.; Saylor, C.R.

    1981-01-01

    The third year of the accelerated reliability testing program concentrated on electrical measurement instrumentation and in modeling cell behavior in the second quadrant. In addition, some preliminary work was done on correlating cell color changes with electrical degradation. Not reported are results of continuing accelerated stress tests on state of the art cells. A number of new cells were added to the program, but not in time for sufficient data to be obtained, while the older cells are undergoing extended test periods and new data are not yet available on them. The all-digital, microprocessor controlled, short interval tester, which was designed and fabricated, has replaced the manual measurement procedure formerly used. This has improved measurement accuracy and repeatability, reduced measurement time, and through coordinated data management procedures, eliminated data errors. A complete description of the tester including schematics and software is given and its operating procedures described. A computer model, based on the thermal and electrical properties of the cells and encapsulating materials, was developed to relate cell temperature to electrical characteristics in the second quadrant. This model adequately predicted the behavior of both encapsulated and unencapsulated cells, although accurate temperature measurements on encapsulated cells were difficult to obtain. In addition, only cells of one type were used for comparison and other cell types may require different parameter values for fitting. Use of the model should permit the prediction of a cell's sensitivity to degradation in the second quadrant. The computer program is listed together with a description of its operation.

  2. Accelerated adhesion of grafted skins by laser-induced stress wave-based gene transfer of hepatocyte growth factor

    Aizawa, Kazuya; Sato, Shunichi; Saitoh, Daizoh; Tsuda, Hitoshi; Ashida, Hiroshi; Obara, Minoru

    2009-02-01

    In our previous study, we delivered plasmid DNA coding for human hepatocyto growth factor (hHGF) to rat skin grafts based on laser-induced stress wave (LISW), by which production of CD31-positive cells in the grafted skins was found to be enhanced, suggesting improved angiogenesis. In this study, we validated the efficacy of this method to accelerate adhesion of grafted skins; reperfusion and reepithelialization in the grafted skins were examined. As a graft, dorsal skin of a rat was exsected and its subcutaneous fat was removed. Plasmid DNA expression vector for hHGF was injected into the graft; on its back surface a laser target with a transparent sheet for plasma confinement was placed, and irradiated with three nanosecond laser pulses at a laser fluence of 1.2 J/cm2 (532 nm; spot diameter, 3 mm) to generate LISWs. After the application of LISWs, the graft was transplanted onto its donor site. We evaluated blood flow by laser Doppler imaging and analyzed reepithelialization based on immunohistochemistry as a function of postgrafting time. It was found that both reperfusion and reepithelialization were significantly enhanced for the grafts with gene transfection than for normal grafts; reepithelialization was completed within 7 days after transplantation with the transfected grafts. These findings demonstrate that adhesion of grafted skins can be accelerated by delivering HGF gene to the grafts based on LISWs.

  3. Usefulness of an accelerated transoesophageal stress echocardiography in the preoperative evaluation of high risk severely obese subjects awaiting bariatric surgery

    Tessier Michel

    2010-07-01

    Full Text Available Abstract Background Severe obesity is associated with an increased risk of coronary artery disease (CAD. Bariatric surgery is an effective procedure for long term weight management as well as reduction of comorbidities. Preoperative evaluation of cardiac operative risk may often be necessary but unfortunately standard imaging techniques are often suboptimal in these subjects. The purpose of this study was to demonstrate the feasibility, safety and utility of transesophageal dobutamine stress echocardiography (TE-DSE using an adapted accelerated dobutamine infusion protocol in severely obese subjects with comorbidities being evaluated for bariatric surgery for assessing the presence of myocardial ischemia. Methods Subjects with severe obesity [body mass index (BMI >40 kg/m2] with known or suspected CAD and being evaluated for bariatric surgery were recruited. Results Twenty subjects (9M/11F, aged 50 ± 8 years (mean ± SD, weighing 141 ± 21 kg and with a BMI of 50 ± 5 kg/m2 were enrolled in the study and underwent a TE-DSE. The accelerated dobutamine infusion protocol used was well tolerated. Eighteen (90% subjects reached their target heart rate with a mean intubation time of 13 ± 4 minutes. Mean dobutamine dose was 31.5 ± 9.9 ug/kg/min while mean atropine dose was 0.5 ± 0.3 mg. TE-DSE was well tolerated by all subjects without complications including no significant arrhythmia, hypotension or reduction in blood arterial saturation. Two subjects had abnormal TE-DSE suggestive of myocardial ischemia. All patients underwent bariatric surgery with no documented cardiovascular complications. Conclusions TE-DSE using an accelerated infusion protocol is a safe and well tolerated imaging technique for the evaluation of suspected myocardial ischemia and cardiac operative risk in severely obese patients awaiting bariatric surgery. Moreover, the absence of myocardial ischemia on TE-DSE correlates well with a low operative risk of cardiac event.

  4. Maxwell-Faraday stresses in electromagnetic fields and the self-force on a uniformly accelerating point charge

    The physical analysis of a uniformly accelerating point charge provides a rich problem to explore in advanced courses in electrodynamics and relativity since it brings together fundamental concepts in relation to electromagnetic radiation, Einstein's equivalence principle and the inertial mass of field energy in ways that reveal subtleties in each of these concepts. By first exploring the heuristic value of Maxwell's and Faraday's idea that the electromagnetic field is like a stressed material medium, it is shown in this paper that the problem also provides an interesting application of the electromagnetic stress-energy-momentum tensor and that an analysis using this tensor provides clear physical insight into this highly subtle and contentious problem and the so-called '4/3 problem' of classical electromagnetic theory. In particular, it is shown that the stress force on a uniformly accelerating, uniformly charged spherical shell due to its own field is simply the (relativistic) inertial mass of the charge's electrostatic field times the acceleration. Since the inertial mass of the electromagnetic field forms part of the observed rest mass of a charged particle, it is argued that the results are therefore consistent with the Lorentz-Abraham-Dirac equation of motion for an accelerating point charge, which implies that for uniform acceleration, the work done by the force acting on the charge only goes into increasing the kinetic energy of the charge, none goes into the creation of radiation

  5. Thermal stress studies using optical holographic interferometry

    Harris, W. J.; Woods, D. C.

    1974-01-01

    The application of holography to thermal stress studies is discussed. Interference fringes as produced by holograms and their interpretation are reviewed in relation to workpiece displacement. Three potential mechanisms are given to explain thermal displacement as detected by holographic methods. Results of some thermal stressing studies are reported, including tests on a live rocket motor.

  6. Does cyclic stress and accelerated ageing influence the wear behavior of highly crosslinked polyethylene?

    Affatato, Saverio; De Mattia, Jonathan Salvatore; Bracco, Pierangiola; Pavoni, Eleonora; Taddei, Paola

    2016-06-01

    First-generation (irradiated and remelted or annealed) and second-generation (irradiated and vitamin E blended or doped) highly crosslinked polyethylenes were introduced in the last decade to solve the problems of wear and osteolysis. In this study, the influence of the Vitamin-E addition on crosslinked polyethylene (XLPE_VE) was evaluated by comparing the in vitro wear behavior of crosslinked polyethylene (XLPE) versus Vitamin-E blended polyethylene XLPE and conventional ultra-high molecular weight polyethylene (STD_PE) acetabular cups, after accelerated ageing according to ASTM F2003-02 (70.0±0.1°C, pure oxygen at 5bar for 14 days). The test was performed using a hip joint simulator run for two millions cycles, under bovine calf serum as lubricant. Mass loss was found to decrease along the series XLPE_VE>STD_PE>XLPE, although no statistically significant differences were found between the mass losses of the three sets of cups. Micro-Raman spectroscopy was used to investigate at a molecular level the morphology changes induced by wear. The spectroscopic analyses showed that the accelerated ageing determined different wear mechanisms and molecular rearrangements during testing with regards to the changes in both the chain orientation and the distribution of the all-trans sequences within the orthorhombic, amorphous and third phases. The results of the present study showed that the addition of vitamin E was not effective to improve the gravimetric wear of PE after accelerated ageing. However, from a molecular point of view, the XLPE_VE acetabular cups tested after accelerated ageing appeared definitely less damaged than the STD_PE ones and comparable to XLPE samples. PMID:26970299

  7. Study on mitigation of stress corrosion cracking by peening

    In order to verify stability of residual stress improvement effect of peeing for mitigation of stress corrosion cracking in components of PWR plant, relaxation behavior of residual stress induced by water jet peening (WJP) and ultrasonic shot peening (USP) on surface of alloy 600 and its weld metal was investigated under various thermal aging and stress condition considered for actual plant operation. In the case of thermal aging at 320-380degC, surface residual stress relaxation was observed at the early stage of thermal aging, but no significant stress relaxation was observed after that. Applied stress below yield stress does not significantly affect stress relaxation behavior of surface residual stress. Furthermore, it was confirmed that cyclic stress does not accelerate stress relaxation. (author)

  8. Studies on a multichannel RF acceleration system (MEQALAC)

    The present thesis deals with the theoretical and experimental studies on a multichannel RF acceleration system for large currents of heavy ions. After a short introduction the high-frequency properties of the used modified interdigital H-structure was discussed. The resonator was treated in a model of an oscillating circuit with concentred switching elements. With the model the resonator capacitance and inductance were calculated from which the characteristic resonator parameters resulted. The measurements of the distribution of the electric field showed that by application of closed supports a nearly constant voltage slope could be reached for all studied structure types. The voltage distribution could within certain limits be influenced by the capacitance distribution and the distribution of the free area for the radial magnetic field along the accelerator structure. Starting from the KV differential equations by the approximation of a constant external focusing the influence of the misfit of the beams to the channel was described by a perturbation calculation. The beam measurements with the MEQALAC prove its suitability as accelerator for intense ion beams at low incident energy. A maximal He+ beam of fourfold 2 mA was accelerated from 40 to 115 keV by an assembly of four channels, each of them has a radius of only 3 mm. The acceleration efficiency amounts thereby to 50%. (orig./HSI)

  9. Accelerator studies at cooler rings TARN and TARN II

    Two ion cooler rings, TARN and TARN II were constructed and operated from 1975 to 1992 at the Institute for Nuclear Study, Univ. of Tokyo, for mainly accelerator studies concerning the beam accumulation, acceleration and cooling. The main subjects performed in these facilities were; 1) beam stacking in transverse and longitudinal phase spaces, 2) stochastic momentum cooling, 3) electron cooling, 4) synchrotron acceleration and 5) slow beam extraction. In the present paper, typical experimental results on these subjects, arc described as well as the basic physical idea underlying these experimental results. The technical details are out of scope of the present paper. They can be found in the other papers refered in the concerned section in the text. (author)

  10. Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs

    Tveden-Nyborg, Pernille; Andersen, Stine Hasselholt; Miyashita, Namiyo;

    2012-01-01

      Increased oxidative stress in the brain has consistently been implied in ageing and in several degenerative brain disorders. Acting as a pivotal antioxidant in the brain, vitamin C is preferentially retained during deficiency and may play an essential role in neuroprotection during ageing. Thus......, a lack of vitamin C could be associated with an increase in redox imbalance in the ageing brain. The present study compared oxidative stress of ageing to that of a long-term non-scorbutic vitamin C deficiency in guinea pigs. Adults (3-9 months old) were compared to old (36-42 months old) animals...... during a six-month dietary intervention by assessing vitamin C transport and redox homeostasis in the brain. In contrast to our hypothesis, chronic vitamin C deficiency did not affect the measured markers of oxidative stress in the brains of adult and aged animals. However, aged animals generally showed...

  11. Shifting gears: Thermodynamics of genetic information storage suggest stress-dependence of mutation rate, which can accelerate adaptation

    Hilbert, Lennart

    2011-01-01

    Background: Acceleration of adaptation dynamics by stress-induced hypermutation has been found experimentally. Evolved evolvability is a prominent explanation. We investigate a more generally applicable explanation by a physical constraint. Methods and Results: A generic thermodynamical analysis of genetic information storage obviates physical constraints on the integrity of genetic information. The capability to employ metabolic resources is found as a major determinant of mutation probability in stored genetic information. Incorporation into a non-recombinant, asexual adaptation toy model predicts cases of markedly accelerated adaptation, driven by a transient increase of mutation rate. No change in the mutation rate as a genetic trait is required. The mutation rate of one and the same genotype varies dependent on stress level. Implications: Stress-dependent mutation rates are physically necessary and challenge a condition-independent genotype to mutation rate mapping. This holds implications for evolutiona...

  12. Characterization Study of Accelerator for Application in Biotechnology

    The characterization of accelerator for application in biotechnology was studied. Accelerator is a machine to produce ion beam particles. Accelerator can be used for biotechnology experiments. Ion beam particles irradiation on the biological material will produced variabilities of genetics and induced mutations. In general, new varieties were found by hybridization method or mutation breeding method by gamma rays irradiation. Ion beam particles can be used for biological material irradiation to find variabilities of genetics and induced mutations. The high percentage of mutation rate and LET value by ion beam particles irradiation was found higher than by gamma rays irradiation. Ion beam particle irradiation can also be controlled and foewed to target in biological material. The characterization of accelerator needed for biotechnology experiments are types of accelerator (Tandem Van de Graff, AVF Cyclotron, Synchrotron, Rilac), types of ion particles (C, He, electron, Ar, Ne, Ni, Al, Xe and Au), range of energy (5 - 2.090 MeV), range of dose irradiation (10 - 250 Gy), range of ion current (0.02 - 20 nA), range of ion beam particles diameter (10 - 100 μm), range of LET value (300 - 1.800 keV/μm ) and irradiation time (5 - 30 seconds/samples). (author)

  13. Accelerated resolution therapy: an innovative mental health intervention to treat post-traumatic stress disorder.

    Finnegan, Alan; Kip, K; Hernandez, D; McGhee, S; Rosenzweig, L; Hynes, C; Thomas, M

    2016-04-01

    Post-traumatic stress disorder (PTSD) is a disabling trauma and stress-related disorder that may occur after a person experiences a traumatic event, and evokes a combination of intrusion and avoidance symptoms, negative alterations in cognitions and mood, and alterations in arousal and reactivity. Accelerated resolution therapy (ART) is an emerging psychotherapy that provides fast and lasting resolution for mental health problems such as PTSD. ART has been shown to achieve a positive result in one to five sessions, typically over a 2-week period, and requires no homework, skills practice or repeated exposure to targeted events. Initial research, including one randomised control trial, has demonstrated that ART interventions can significantly reduce symptoms of psychological trauma in both civilians and US service members and veterans. These results suggest that ART be considered as either a primary treatment option or for refractory PTSD in those with a suboptimal response to endorsed first-line therapies. Conservative estimates indicate substantial potential cost savings in PTSD treatment. Despite the need for more definitive clinical trials, there is increasing interest in ART in the USA, including in the US Army. The growing positive empirical evidence is compelling, and there appears to be sufficient evidence to warrant UK researchers undertaking ART research. The armed forces offer the potential for comparative international trials. However, equally important are veterans, emergency services personnel and those subjected to violence. ART appears to also have application in other conditions, including depression, anxiety disorders, and alcohol or drug misuse. ART can potentially help personnel traumatised by the unique challenges of war and conflict zones by providing brief psychotherapy in a readily accessible and culturally competent manner. ART facilitates the provision of interventions and resolutions in theatre, thus enhancing forces' fighting capability

  14. Diagnostics for studies of novel laser ion acceleration mechanisms

    Diagnostic for investigating and distinguishing different laser ion acceleration mechanisms has been developed and successfully tested. An ion separation wide angle spectrometer can simultaneously investigate three important aspects of the laser plasma interaction: (1) acquire angularly resolved energy spectra for two ion species, (2) obtain ion energy spectra for multiple species, separated according to their charge to mass ratio, along selected axes, and (3) collect laser radiation reflected from and transmitted through the target and propagating in the same direction as the ion beam. Thus, the presented diagnostic constitutes a highly adaptable tool for accurately studying novel acceleration mechanisms in terms of their angular energy distribution, conversion efficiency, and plasma density evolution

  15. Studies of Nanotube Channeling for Efficient Beam Scraping at Accelerators

    Biryukov, V M

    2005-01-01

    While particle beam steering (and in particular, "scraping") in accelerators by bent channeling crystals is an established technique extensively tested at IHEP Protvino and other major high-energy labs, an interesting question is how one could improve channeling capabilities by applying modern nanotechnology. Theoretical research of nanotube channeling was in progress over recent years. In this work, we assess potential benefits from nanotube channeling for real accelerator systems. We report simulation studies of channeling in nanostructured material (carbon SWNT and MWNT) tested for possible serving as a primary scraper for the collimation systems of hadron colliders. The advantages of nanostructured material as a potential choice for a primary scraper in a high-energy accelerator such as LHC or the Tevatron are discussed in comparison to crystal lattices and amorphous material. We evaluate physical processes relevant to this application and reveal nanotechnology requirements.

  16. Monte Carlo simulations and benchmark studies at CERN's accelerator chain

    AUTHOR|(CDS)2083190; Brugger, Markus

    2015-01-01

    Mixed particle and energy radiation fields present at the Large Hadron Collider (LHC) and its accelerator chain are responsible for failures on electronic devices located in the vicinity of the accelerator beam lines. These radiation effects on electronics and, more generally, the overall radiation damage issues have a direct impact on component and system lifetimes, as well as on maintenance requirements and radiation exposure to personnel who have to intervene and fix existing faults. The radiation environments and respective radiation damage issues along the CERN’s accelerator chain were studied in the framework of the CERN Radiation to Electronics (R2E) project and are hereby presented. The important interplay between Monte Carlo simulations and radiation monitoring is also highlighted.

  17. Continuing studies of the plasma beat wave accelerator

    This is a proposal for the release of third year funds for the ''Plasma Beat Wave Accelerator'' program (PBWA) at UCLA under the direction of Professor C. Joshi. This report is also a summary of progress on this project since March 1990; i.e., the date of the last report to the DOE. Once again we note that although the program is for historical reasons called the Plasma Beat Wave Accelerator Program, our group is active in all areas of applications of lasers and plasmas in future high energy accelerators. These are as follows: heat gradient plasma structures; excited by plasma beat wave technique; laser wake field technique; and plasma wake field technique. Development of a photoinjector-driven, 20 MeV linac; and theoretical studies of the plasma lens and use of plasmas at the final focus

  18. Beat-wave accelerator studies at the Rutherford Appleton Laboratory

    The study carried out in 1982-83 at the Rutherford Appleton Laboratory to examine how one might use the beat-wave principle to construct a useful high energy accelerator is reviewed, and comments are made on later developments. A number of problems are evident to which solutions cannot at present be foreseen. (author)

  19. Accelerated brain aging in schizophrenia : A longitudinal pattern recognition study

    Schnack, Hugo G.; Van Haren, Neeltje E M; Nieuwenhuis, Mireille; Pol, Hilleke E Hulshoff; Cahn, Wiepke; Kahn, René S.

    2016-01-01

    OBJECTIVE: Despite the multitude of longitudinal neuroimaging studies that have been published, a basic question on the progressive brain loss in schizophrenia remains unaddressed: Does it reflect accelerated aging of the brain, or is it caused by a fundamentally different process? The authors used

  20. ACCELERATED STABILITY STUDIES OF A POLYHERBAL PREPARATION (EAZMOVR) CAPSULE

    Chauhan, S K; A. Tyagi; Singh, B.; Agarwal, S.

    1999-01-01

    The stability of Eazmov capsule in accelerated condition ie by exposing it to the temperature at 45°C and 40°C with 75% relative humidity was studied. The samples were periodically anallysed upto six months for their organoleptic characteristics, assay of active plant ingredients and the DPTLC finger printing and their peak area analysis, which were found to be stable/ consistent during the period of study. The change in quantifiable components was within 90% of the initial amount, indicating...

  1. Dedicated medical ion accelerator design study. Final report

    Results and conclusions are reported from a design study for a dedicated medical accelerator. Basing efforts on the current consensus regarding medical requirements, the resulting demands on accelerator and beam delivery systems were analyzed, and existing accelerator technology was reviewed to evaluate the feasibility of meeting these demands. This general analysis was augmented and verified by preparing detailed preliminary designs for sources of therapeutic beams of neutrons, protons and heavy ions. The study indicates that circular accelerators are the most desirable and economical solutions for such sources. Synchrotrons are clearly superior for beams of helium and heavier ions, while synchrotrons and cyclotrons seem equally well suited for protons although they have different strengths and weaknesses. Advanced techniques of beam delivery are of utmost importance in fully utilizing the advantages of particle beams. Several issues are invloved here. First, multi-treatment room arrangements are essential for making optimal use of the high dose rate capabilities of ion accelerators. The design of corresponding beam switching systems, the principles of which are already developed for physics experimental areas, pose no problems. Second, isocentric beam delivery substantially enhances flexibility of dose delivery. After several designs for such devices were completed, it was concluded that high field magnets are necessary to keep size, bulk and cost acceptable. Third, and most important, is the generation of large, homogeneous radiation fields. This is presently accomplished with the aid of scattering foils, occluding rings, collimators, ridge filters, and boluses. A novel approach, three-dimensional beam scanning, was developed here, and the most demanding components of such a system (fast-scanning magnet and power supply) were built and tested

  2. A comparative study of accelerated tests to simulate atmospheric corrosion

    In this study, specimens coated with five organic coating systems were exposed to accelerated tests for periods up to 2000 hours, and also to weathering for two years and six months. The accelerated tests consisted of the salt spray test, according to ASTM B-117; Prohesion (ASTM G 85-98 annex 5A); Prohesion combined with cyclic exposure to UV-A radiation and condensation; 'Prohchuva' a test described by ASTM G 85-98 using a salt spray with composition that simulated the acid rain of Sao Paulo, but one thousand times more concentrated, and 'Prohchuva' combined with cyclic exposure to UV-A radiation and condensation. The coated specimens were exposed with and without incision to expose the substrate. The onset and progress of corrosion at and of the exposed metallic surface, besides coating degradation, were followed by visual observation, and photographs were taken. The coating systems were classified according to the extent of corrosion protection given to the substrate, using a method based on ASTM standards D-610, D-714, D-1654 and D-3359. The rankings of the coatings obtained from accelerated tests and weathering were compared and contrasted with classification of the same systems obtained from literature, for specimens exposed to an industrial atmosphere. Coating degradation was strongly dependent on the test, and could be attributed to differences in test conditions. The best correlation between accelerated test and weathering was found for the test Prohesion alternated with cycles of exposure to UV-A radiation and condensation. (author)

  3. Experimental studies of plasma wake-field acceleration and focusing

    More than four years after the initial proposal of the Plasma Wake-field Accelerator (PWFA), it continues to be the object of much investigation, due to the promise of the ultra-high accelerating gradients that can exist in relativistic plasma waves driven in the wake of charged particle beams. These large amplitude plasma wake-fields are of interest in the laboratory, both for the wealth of basic nonlinear plasma wave phenomena which can be studied, as well as for the applications of acceleration of focusing of electrons and positrons in future linear colliders. Plasma wake-field waves are also of importance in nature, due to their possible role in direct cosmic ray acceleration. The purpose of the present work is to review the recent experimental advances made in PWFA research at Argonne National Laboratory, in which many interesting beam and plasma phenomena have been observed. Emphasis is given to discussion of the nonlinear aspects of the PWFA beam-plasma interaction. 29 refs., 13 figs

  4. The accelerator driven transmutation technology - A study on the linac for proton accelerator

    Han, Bum Soo; Joh, Ki Hun; Kim, Sung Myun; Park, Heung Gyu; Park, Jong Pil; Kang, Bo Sun [Samsung Heavy Industries, Taejon (Korea)

    1999-04-01

    The purpose of this study is to investigate the manufacturing technology of proton accelerators, and to find the adequate manufacturing technique for construction of such proton accelerators. Review of manufacturing technology for RFQ has been carried out - RFQ machine of other country has been reviewed on the aspects of manufacturing, - Machining of engineering mock-up has been performed based on the designed data, - Brazing technology for RFQ, and brazing test and analysis of Copper specimen. Adequate brazing conditions for RFQ - 1st brazing (vane to section, 950 deg C), Filler metal composition: Cu-20Sn, Brazing conditions: peak temp. 950 deg C (holding time 20min, rising rate 7 deg C/min), Atmosphere: H{sub 2}. - 2nd brazing (section to section, 850 deg C or less), Filler metal: Cu-Sn4%-P7.5%-Ag6%, Brazing conditions: peak temp. 750 deg C (holding time 20min, rising rate 7 deg C/min), Atmosphere: H{sub 2}. 8 refs., (author). 31 figs., 6 tabs.

  5. Feasibility Study on the Development of Proton Accelerator II

    Whang, Ki Woong [Korea Accelerator and Plasma Research Association, Seoul (Korea, Republic of)

    1997-09-01

    Present status and research trend of KOMAC (Korea Multipurpose Accelerator Complex)-grade accelerator construction in Europe, Japan, America, and Russia are surveyed in view of basic nuclear technology study in 2nd feasibility study on the KOMAC. KOMAC can be applied to study the increasing of nuclear reactor safety, the Proto-plant of transmutation technology for low cost nuclear fuel, the nuclear data production, the life science, mechanical dynamics, the structure probe, the radioisotope production, the cancer therapy, and the defense industry etc. And also KOMAC structure selection is investigated in point of utilization aims referred from various proposal of LANL and ORNL in USA, Neutron Science Research program in Japan, Energy Amplifier in Europe, and Institute of Theoretical and Experimental physics in Russia. As a result of meeting, study team is approached to the conclusion the KOMAC should be constructed to get the nuclear transmutation technology and the world leadership in future nuclear industry. Member`s opinion of study team agreed new nuclear technology, such as Accelerator Driven Energy Amplifier will be possible to sustain a survival of human being in post 21c. 7 tabs., 10 figs. (author)

  6. Biometric study using hyperspectral imaging during stress

    Nagaraj, Sheela; Quoraishee, Shafik; Chan, Gabriel; Short, Kenneth R.

    2010-04-01

    To the casual observer, transient stress results in a variety of physiological changes that can be seen in the face. Although the conditions can be seen visibly, the conditions affect the emissivity and absorption properties of the skin, which imaging spectrometers, commonly referred to as Hyperspectral (HS) cameras, can quantify at every image pixel. The study reported on in this paper, using Hyperspectral cameras, provides a basis for continued study of HS imaging to eventually quantify biometric stress. This study was limited to the visible to near infrared (VNIR) spectral range. Signal processing tools and algorithms have been developed and are described for using HS face data from human subjects. The subjects were placed in psychologically stressful situations and the camera data were analyzed to detect stress through changes in dermal reflectance and emissivity. Results indicate that hyperspectral imaging may potentially serve as a non-invasive tool to measure changes in skin emissivity indicative of a stressful incident. Particular narrow spectral bands in the near-infrared region of the electromagnetic spectrum seem especially important. Further studies need to be performed to determine the optimal spectral bands and to generalize the conclusions. The enormous information available in hyperspectral imaging needs further analysis and more spectral regions need to be exploited. Non-invasive stress detection is a prominent area of research with countless applications for both military and commercial use including border patrol, stand-off interrogation, access control, surveillance, and non-invasive and un-attended patient monitoring.

  7. Study of electrostatic acceleration of H and D negative ion beams. Application to the 1 MeV SINGAP accelerator

    In the framework of the development of a neutral beam injection system for ITER (International Thermonuclear Experimental Reactor), the electrostatic acceleration of negative ion H/D beams up to an energy of 1 MeV has been studied. With the support of 3-D beam trajectory calculations, the limitations of the multi-aperture multi-grid acceleration concept, ITER reference concept, ar shown and the relevance of a new concept, called SINGAP, is demonstrated. In a SINGAP accelerator, beamlets are pre-accelerated with a classical triode multi-apertures system up to ∼ 50 keV. The pre-accelerated beamlets are then merged into a single beam and post-accelerated at high energy through a large SINGle APerture using one SINgle GAP. The optics of one pre-accelerated beamlet has been studied on the INCA triode accelerator at the Ecole Polytechnique. A diagnostic has been developed to measure the emittance of the pre-accelerated beamlet. A diagnostic has been developed to measure the emittance of the pre-accelerated beamlet. Values of ∼ 0.03π.mrad.cm for the effective normalized emittance and ∼ 12 mrad for the minimal beam divergence have been found (Hbeams). Besides, the effects of co-extracted electrons and pressure in the transport region on the beam optics are shown and experiment is compared to beam numerical simulation. On the Cadarache 1 MeV, 100 mA, D- SINGAP accelerator, beams of 1 s pulse were produced at a level of 900 keV (without observing breakdowns between electrodes). SINGAP optics has been investigated using an infrared calorimetric beam profile diagnostic (2-D) and a neutral beam profile diagnostic (1-D). The control of the beam optics is very satisfying: a divergence of ∼ 10 mrad has been measured, and 3-D simulations and experimentation are in good agreement. (author)

  8. Comparative study of acceleration transducers for biomedical applications

    Buchczik, Dariusz; Wyżgolik, Roman; Pietraszek, Stanisław

    2006-10-01

    The results of comparative studies of the metrological parameters of acceleration transducers constructed in Institute of Electronics, Silesian University of Technology is presented in this article. The construction of the transducers is based on commercially available monolithic accelerometers and optimized for biomedical applications. The parameters determined during the tests are similar to the parameters of the monolithic accelerometers declared by their manufacturers. It proofs that both the mechanical and the electronic construction of the transducers are correct.

  9. Study of the Accelerator Technology Development for Cancer Radiotherapy

    The hadronic particle beams including both protons, neutrons and charged particles have been studied for cancer therapy by a number of research centers in several countries during the past two decades. In this paper is briefly discussed concerning the accelerator type and its applications. The future trends are seen in the new technological developments like the use of proton gantries, beam scanning techniques, improved patient handling system and in the increasing precision of treatment. (author)

  10. Cluster in situ studies of the auroral acceleration region

    Li, Bin

    2014-01-01

    This thesis addresses a central topic in auroral physics, namely particle accelerationproducing intense aurora as well as energetic plasma outflow. Cluster satellitemeasurements of electric and magnetic fields, electrons and ions, collected across auroralfield lines, are used to study various aspects of the quasi-static auroral accelerationregion (AAR), its relation to the auroral density cavity, and the relative role of quasistaticand Alfvénic acceleration for producing aurora.The accelerati...

  11. Studies of hydrogen pellet acceleration with fuseless electromagnetic railgun

    A fuseless circular-bore electromagnetic railgun specifically designed for injection of high-velocity hydrogen pellets was constructed and tested. Hydrogen pellets were first accelerated to medium velocities (∼ 500 m/s) using a gas gun and then injected into the railgun. Once a pellet entered the railgun, a plasma arc was initiated by electrically breaking down the propellant gas which followed the pellet from the gas gun into the railgun. Utilizing the propulsive force of this plasma arc armature, further acceleration of the hydrogen pellet was achieved. Using a 60 cm long railgun, proof-of-principle experiments were performed on hydrogen pellets, 1.6 mm, in diameter and 2.15 mm in length, producing velocities exceeding 1.5 km/s. Encouraged by this preliminary success, more extensive studies are in progress to further improve the performance and capabilities of the current system

  12. Mechanical stability study for Integrable Optics Test Accelerator at Fermilab

    McGee, M W; Carlson, K; Leibfritz, J; Nobrega, L; Valishev, A

    2016-01-01

    The Integrable Optics Test Accelerator (IOTA) is proposed for operation at Fermilab. The goal of IOTA is to create practical nonlinear accelerator focusing systems with a large frequency spread and stable particle motion. The IOTA is a 40 m circumference, 150 MeV (e-), 2.5 MeV (p+) diagnostic test ring. A heavy low frequency steel floor girder is proposed as the primary tier for IOTA device component support. Two design lengths; (8) 3.96 m and (2) 3.1 m long girders with identical cross section completely encompass the ring. This study focuses on the 3.96 m length girder and the development of a working prototype. Hydrostatic Level Sensor (HLS), temperature, metrology and fast motion measurements characterize the anticipated mechanical stability of the IOTA ring.

  13. Mechanical Stability Study for Integrable Optics Test Accelerator at Fermilab

    McGee, Mike [Fermilab; Andrews, Richard [Fermilab; Carlson, Kermit [Fermilab; Leibfritz, Jerry [Fermilab; Nobrega, Lucy [Fermilab; Valishev, Alexander [Fermilab

    2016-07-01

    The Integrable Optics Test Accelerator (IOTA) is proposed for operation at Fermilab. The goal of IOTA is to create practical nonlinear accelerator focusing systems with a large frequency spread and stable particle motion. The IOTA is a 40 m circumference, 150 MeV (e-), 2.5 MeV (p⁺) diagnostic test ring. A heavy low frequency steel floor girder is proposed as the primary tier for IOTA device component support. Two design lengths; (8) 4 m and (2) 2.8 m long girders with identical cross section completely encompass the ring. This study focuses on the 4 m length girder and the development of a working prototype. Hydrostatic Level Sensor (HLS), temperature, metrology and fast motion measurements characterize the anticipated mechanical stability of the IOTA ring.

  14. Application of accelerator mass spectrometry in aluminum metabolism studies

    The recent recognition that aluminum causes toxicity in uremic patients and may be associated with Alzheimer's disease has stimulated many studies of its biochemical effects. However, such studies were hampered by the lack of a suitable tracer. In a novel experiment, we have applied the new technique of accelerator mass spectrometry to investigate aluminum kinetics in rats, using as a marker the long-lived isotope 26Al. We present the first aluminum kinetic model for a biological system. The results clearly demonstrate the advantage this technique holds for isotope tracer studies in animals as well as humans. (Author) (24 refs., 3 figs.)

  15. Development of an accelerated test for Internal Sulfate Attack study

    Khelil Nacim

    2014-04-01

    Full Text Available Internal Sulfate Attack (ISA is a pathology that occurs under certain conditions in concrete having undergone heating above 70 °C at early age (through heating in pre-casting industry or due to hydration in large concrete parts. This reaction deemed very slow, numerous methods to speed up reactions leading to delayed ettringite formation have been developed. These methods are all based on the material damage. Another type of test is currently under development. It is based on rehabilitation techniques such as electrochemical chloride extraction (ECE in order to accelerate the leaching of alkalis that could be one of the triggers of the pathology. The study presented in this paper focused on concrete specimens prepared from cement (CEM I 52.5 N enriched with Na2SO4. These concretes have undergone a heat treatment typical of those used in precast plants (up to 24 hours with a maximum temperature of 80 °C. Various paths were explored for the development of the accelerated test. The first results showed that it was necessary to use a removable titanium anode ruthenium anode instead of stainless steel embedded in the concrete. Then tests with de-ionized water as the solute to the cathode did not accelerate the onset of expansions. The experiment has been modified and potassium carbonate was added to the solution. This modification didn’t show any significant improvement, and other experiments are being carried out to explain this result.

  16. Aluminum ions accelerated the oxidative stress of copper-mediated melanin formation

    Di, Junwei; Bi, Shuping

    2003-11-01

    A comparison between the effects of aluminum and cupric ions on the dopachrome (DC) conversion and the cooperation effect of the both ions in the DOPA oxidation to melanin pathway has been studied by UV-Vis spectrophotometric method. Both aluminum and cupric ions catalyze the DC conversion reaction, which is an important step in the melanin synthesis pathway. However, cupric ions catalyze the conversion of DC to yield 5,6-dihydroxyindole-2-carboxylic acid (DHICA) but the product of DC conversion catalyzed by aluminum is 5,6-dihydroxyindole (DHI). DOPA oxidation catalyzed by aluminum and cupric ions is studied in the presence of hydrogen peroxide. The results from our experiments provide evidence that aluminum can markedly increase the oxidative stress of copper-mediated the melanin formation and influence the properties of the melanin by means of changing the ratio of DHICA/DHI in the acidic environment (pH 5.5).

  17. Life prediction of 808nm high power semiconductor laser by accelerated life test of constant current stress

    Yao, Nan; Li, Wei; Zhao, Yihao; Zhong, Li; Liu, Suping; Ma, Xiaoyu

    2015-10-01

    High power semiconductor laser is widely used because of its high transformation efficiency, good working stability, compact volume and simple driving requirements. Laser's lifetime is very long, but tests at high levels of stress can speed up the failure process and shorten the times to failure significantly. So accelerated life test is used here for forecasting the lifetime of 808nm CW GaAs/AlGaAs high power semiconductor laser that has an output power of 1W under 1.04A. Accelerated life test of constant current stress based on the Inverse Power Law Relationship was designed. Tests were conducted under 1.3A, 1.6A and 1.9A at room temperature. It is the first time that this method is used in the domestic research of laser's lifetime prediction. Applying Weibull Distribution to describe the lifetime distribution and analyzing the data of times to failure, characteristics lifetime's functional relationship model with current is achieved. Then the characteristics lifetime under normal current is extrapolated, which is 9473h. Besides, to confirm the validity of the functional relationship model, we conduct an additional accelerated life test under 1.75A. Based on this experimental data we calculated the characteristics lifetime corresponding to 1.75A that is 171h, while the extrapolated characteristics lifetime from the former functional relationship model is 162h. The two results shows 5% deviation that is very low and acceptable, which indicates that the test design is reasonable and authentic.

  18. Understanding How Kurtosis Is Transferred from Input Acceleration to Stress Response and Its Influence on Fatigue Llife

    Kihm, Frederic; Rizzi, Stephen A.; Ferguson, Neil S.; Halfpenny, Andrew

    2013-01-01

    High cycle fatigue of metals typically occurs through long term exposure to time varying loads which, although modest in amplitude, give rise to microscopic cracks that can ultimately propagate to failure. The fatigue life of a component is primarily dependent on the stress amplitude response at critical failure locations. For most vibration tests, it is common to assume a Gaussian distribution of both the input acceleration and stress response. In real life, however, it is common to experience non-Gaussian acceleration input, and this can cause the response to be non-Gaussian. Examples of non-Gaussian loads include road irregularities such as potholes in the automotive world or turbulent boundary layer pressure fluctuations for the aerospace sector or more generally wind, wave or high amplitude acoustic loads. The paper first reviews some of the methods used to generate non-Gaussian excitation signals with a given power spectral density and kurtosis. The kurtosis of the response is examined once the signal is passed through a linear time invariant system. Finally an algorithm is presented that determines the output kurtosis based upon the input kurtosis, the input power spectral density and the frequency response function of the system. The algorithm is validated using numerical simulations. Direct applications of these results include improved fatigue life estimations and a method to accelerate shaker tests by generating high kurtosis, non-Gaussian drive signals.

  19. Diffusive shock acceleration at laser driven shocks: studying cosmic-ray accelerators in the laboratory

    Reville, B; Gregori, G

    2012-01-01

    The non-thermal particle spectra responsible for the emission from many astrophysical systems are thought to originate from shocks via a first order Fermi process otherwise known as diffusive shock acceleration. The same mechanism is also widely believed to be responsible for the production of high energy cosmic rays. With the growing interest in collisionless shock physics in laser produced plasmas, the possibility of reproducing and detecting shock acceleration in controlled laboratory experiments should be considered. The various experimental constraints that must be satisfied are reviewed. It is demonstrated that several currently operating laser facilities may fulfil the necessary criteria to confirm the occurrence of diffusive shock acceleration of electrons at laser produced shocks. Successful reproduction of Fermi acceleration in the laboratory could open a range of possibilities, providing insight into the complex plasma processes that occur near astrophysical sources of cosmic rays.

  20. Numerical studies of multipactor in dielectric-loaded accelerator structures

    Sinitsyn, Oleksandr; Nusinovich, Gregory; Antonsen, Thomas

    2009-11-01

    Multipactor (MP) is known as the avalanche growth of the number of secondary electrons emitted from a solid surface exposed to an rf electric field under vacuum conditions. MP may occur in various microwave and rf systems such as microwave tubes, rf windows and launchers, accelerating structures, and rf satellite payloads. In this work we present results of MP analysis in dielectric-loaded accelerator (DLA) structures. The starting point of our work was experimental and theoretical studies of DLA structures jointly done by Argonne National Laboratory and Naval Research Laboratory (J. G. Power et al., Phys. Rev. Lett. 92, 164801 (2004); J. G. Power et al., AIP Conf. Proc. 877, 362 (2006)). In the theoretical model developed during those studies the space-charge field due to the total number of particles is taken into account as a parameter. We perform our studies using a self-consistent approach with the help of time-dependent two-dimensional code developed at the University of Maryland (O. V. Sinitsyn et al., Phys. Plasmas 16, 073102 (2009)). Results include analysis of MP evolution at an early stage, detailed studies of individual electron trajectories, analysis of MP onset time under various conditions and comparison of some results with the experimental data.

  1. Studies of ablation pressure, ablative acceleration and ablative implosions

    Time and space resolved X-ray spectroscopy have been used to measure ablation rate and ablation pressure on plane targets irradiated by the first and second harmonics of Nd glass laser light. Streaked X-ray shadowgraphy has been applied to the study of ablatively imploded spherical shell targets uniformly irradiated by six 1.05 μm laser beams. The results give a direct measurement of shell acceleration and thus of ablation pressure and show evidence of fluid instability increasing as the shell ratio is varied from 10 to 100. A direct determination of implosion core density is also obtained. (author)

  2. Study of a multi-beam accelerator driven thorium reactor

    The primary advantages that accelerator driven systems have over critical reactors are: (1) Greater flexibility regarding the composition and placement of fissile, fertile, or fission product waste within the blanket surrounding the target, and (2) Potentially enhanced safety brought about by operating at a sufficiently low value of the multiplication factor to preclude reactivity induced events. The control of the power production can be achieved by vary the accelerator beam current. Furthermore, once the beam is shut off the system shuts down. The primary difference between the operation of an accelerator driven system and a critical system is the issue of beam interruptions of the accelerator. These beam interruptions impose thermo-mechanical loads on the fuel and mechanical components not found in critical systems. Studies have been performed to estimate an acceptable number of trips, and the value is significantly less stringent than had been previously estimated. The number of acceptable beam interruptions is a function of the length of the interruption and the mission of the system. Thus, for demonstration type systems and interruption durations of 1sec 5mins 2500/yr and 50/yr are deemed acceptable. However, for industrial scale power generation without energy storage type systems and interruption durations of t 5mins, the acceptable number of interruptions are 25000, 2500, 250, and 3 respectively. However, it has also been concluded that further development is required to reduce the number of trips. It is with this in mind that the following study was undertaken. The primary focus of this study will be the merit of a multi-beam target system, which allows for multiple spallation sources within the target/blanket assembly. In this manner it is possible to ameliorate the effects of sudden accelerator beam interruption on the surrounding reactor, since the remaining beams will still be supplying source neutrons. The proton beam will be assumed to have an

  3. Stress and efficiency studies in EFG

    1986-01-01

    The goals of this program were: (1) to define minimum stress configurations for silicon sheet growth at high speeds; (2) to quantify dislocation electrical activity and their limits on minority carrier diffusion length in deformed silicon; and (3) to study reasons for degradation of lifetime with increases in doping level in edge-defined film-fed growth (EFG) materials. A finite element model was developed for calculating residual stress with plastic deformation. A finite element model was verified for EFG control variable relationships to temperature field of the sheet to permit prediction of profiles and stresses encountered in EFG systems. A residual stress measurement technique was developed for finite size EFG material blanks using shadow Moire interferometry. Transient creep response of silicon was investigated in the temperature range between 800 and 1400 C in strain and strain regimes of interest in stress analysis of sheet growth. Quantitative relationships were established between minority carrier diffusion length and dislocation densities using Electron Beam Induced Current (EBIC) measurement in FZ silicon deformed in four point bending tests.

  4. Brief Treatment of Symptoms of Post-Traumatic Stress Disorder (PTSD by Use of Accelerated Resolution Therapy (ART®

    Kevin E. Kip

    2012-06-01

    Full Text Available Post-Traumatic Stress Disorder (PTSD is a prevalent, disabling anxiety disorder. This prospective cohort study reports on a new exposure-based therapy known as Accelerated Resolution Therapy (ART® that incorporates the use of eye movements administered in a brief treatment period (1–5 one-hour sessions within three weeks. Eighty adults aged 21–60 years with symptoms of PTSD were recruited from the Tampa Bay area. The ART-based psychotherapy was designed to minimize anxiety and body sensations associated with recall of traumatic memories and to replace distressing images with favorable ones. Participants’ mean age was 40 years, 77% were female, and 29% were Hispanic. Participants underwent a median of three ART sessions, 66 of 80 (82.5% completed treatment, and 54 of 66 (81.8% provided 2-month follow-up data. Mean scores pre- and post-ART and at 2-month follow-up were: PTSD Checklist: 54.5 ± 12.2 vs. 31.2 ± 11.4 vs. 30.0 ± 12.4; Brief Symptom Inventory: 30.8 ± 14.6 vs. 10.1 ± 10.8 vs. 10.1 ± 12.1; Center for Epidemiologic Studies Depression Scale: 29.5 ± 10.9 vs. 11.8 ± 11.1 vs. 13.5 ± 12.1; Trauma Related Growth Inventory-Distress scale: 18.9 ± 4.1 vs. 7.4 ± 5.9 vs. 8.2 ± 5.9 (p < 0.0001 for all pre-ART vs. post-ART and 2-month comparisons. No serious adverse events were reported. ART appears to be a brief, safe, and effective treatment for symptoms of PTSD.

  5. Biotic stress accelerates formation of climate-relevant aerosols in boreal forests

    J. Joutsensaari

    2015-04-01

    Full Text Available Boreal forests are a major source of climate-relevant biogenic secondary organic aerosols (SOA and will be greatly influenced by increasing temperature. Global warming is predicted to increase emissions of reactive biogenic volatile organic compounds (BVOC from vegetation directly, but will also induce large-scale insect outbreaks, which significantly increase emissions of reactive BVOC. Thus, climate change factors could substantially accelerate the formation of biogenic SOA in the troposphere. In this study, we have combined results from field and laboratory experiments, satellite observations and global scale modelling in order to evaluate the effects of insect herbivory and large-scale outbreaks on SOA formation and the Earth's climate. Field measurements demonstrated 11-fold and 20-fold increases in monoterpene and sesquiterpene emissions, respectively, from damaged trees during a pine sawfly (Neodiprion sertifer outbreak in eastern Finland. Laboratory chamber experiments showed that feeding by pine weevils (Hylobius abietis increased VOC emissions from Scots pine and Norway spruce seedlings by 10–50 fold resulting in 200–1000 fold increases in SOA masses formed via ozonolysis. The influence of insect damage on aerosol concentrations in boreal forests was studied with a global chemical transport model GLOMAP and MODIS satellite observations. Global scale modelling was performed using a 10-fold increase in monoterpene emission rates and assuming 10% of the boreal forest area was experiencing outbreak. Results showed a clear increase in total particulate mass (local max. 480% and cloud condensation nuclei concentrations (45%. Satellite observations indicated a two-fold increase in aerosol optical depth (AOD over western Canada's pine forests in August during a bark beetle outbreak. These results suggest that more frequent insect outbreaks in a warming climate could result in substantial increase in biogenic SOA formation in the boreal

  6. Biotic stress accelerates formation of climate-relevant aerosols in boreal forests

    Joutsensaari, J.; Yli-Pirilä, P.; Korhonen, H.; Arola, A.; Blande, J. D.; Heijari, J.; Kivimäenpää, M.; Mikkonen, S.; Hao, L.; Miettinen, P.; Lyytikäinen-Saarenmaa, P.; Faiola, C. L.; Laaksonen, A.; Holopainen, J. K.

    2015-11-01

    Boreal forests are a major source of climate-relevant biogenic secondary organic aerosols (SOAs) and will be greatly influenced by increasing temperature. Global warming is predicted to not only increase emissions of reactive biogenic volatile organic compounds (BVOCs) from vegetation directly but also induce large-scale insect outbreaks, which significantly increase emissions of reactive BVOCs. Thus, climate change factors could substantially accelerate the formation of biogenic SOAs in the troposphere. In this study, we have combined results from field and laboratory experiments, satellite observations and global-scale modelling in order to evaluate the effects of insect herbivory and large-scale outbreaks on SOA formation and the Earth's climate. Field measurements demonstrated 11-fold and 20-fold increases in monoterpene and sesquiterpene emissions respectively from damaged trees during a pine sawfly (Neodiprion sertifer) outbreak in eastern Finland. Laboratory chamber experiments showed that feeding by pine weevils (Hylobius abietis) increased VOC emissions from Scots pine and Norway spruce seedlings by 10-50 fold, resulting in 200-1000-fold increases in SOA masses formed via ozonolysis. The influence of insect damage on aerosol concentrations in boreal forests was studied with a global chemical transport model GLOMAP and MODIS satellite observations. Global-scale modelling was performed using a 10-fold increase in monoterpene emission rates and assuming 10 % of the boreal forest area was experiencing outbreak. Results showed a clear increase in total particulate mass (local max. 480 %) and cloud condensation nuclei concentrations (45 %). Satellite observations indicated a 2-fold increase in aerosol optical depth over western Canada's pine forests in August during a bark beetle outbreak. These results suggest that more frequent insect outbreaks in a warming climate could result in substantial increase in biogenic SOA formation in the boreal zone and, thus

  7. Studies of Al metabolism in animal by accelerator mass spectrometry

    WangNa-Xiu; ZhuHan-Min; 等

    1997-01-01

    The correlation between Al metabolism and senile dementia in animal has been studied by AMS(accelerator mass spectrometry).Three groups of laboratory rats were fed with normal food.food with high Al content,and with enriched Ca and Mg together with high Al,respectively for six to eight months.Mapping test was made to recored th degree of wisdom degeneration.Half of the rats were sacrificed and Al contents in various organs were measured by atomic absorption spectroscopy.The rest were injected with 26Al,killed after 5,10,15,25,and 35d and 26Al contents measured by AMS.The distribution of Al as well as the correlation among the accumulation of 26Al,and the existed Al content and dementia was studied.

  8. An Experimental Study of a Pulsed Electromagnetic Plasma Accelerator

    Thio, Y. C. Francis; Eskridge, Richard; Lee, Mike; Smith, James; Martin, Adam; Markusic, Tom E.; Cassibry, Jason T.; Rodgers, Stephen L. (Technical Monitor)

    2002-01-01

    Experiments are being performed on the NASA Marshall Space Flight Center (MSFC) pulsed electromagnetic plasma accelerator (PEPA-0). Data produced from the experiments provide an opportunity to further understand the plasma dynamics in these thrusters via detailed computational modeling. The detailed and accurate understanding of the plasma dynamics in these devices holds the key towards extending their capabilities in a number of applications, including their applications as high power (greater than 1 MW) thrusters, and their use for producing high-velocity, uniform plasma jets for experimental purposes. For this study, the 2-D MHD modeling code, MACH2, is used to provide detailed interpretation of the experimental data. At the same time, a 0-D physics model of the plasma initial phase is developed to guide our 2-D modeling studies.

  9. Stress among Malaysian Academics: A Conceptual Study

    Zafir Mohd Makhbul

    2013-01-01

    Full Text Available Academic stress had been prevalent in universities all around the world. This shows that the academic environment no longer provides the low-stress working environment that the academician once enjoyed. Rapid development, global competition, technology and changes in the nature of jobs today could make the job more demanding than ever, and workers are more prone to injuries and illnesses. Stressors such as work relationship, work-life balance, job overload, job control, job security, pay and benefits, resources and communication, as well as aspects of the job could also be the source of pressure in the workplace. As the effects of the stressors, individual and organizational commitment, as well as physical health and psychological well-being of the employees will suffer. This in turn will impede the productivity of the organization such as teaching, supervision, publication, training, student service, administrative duties, and social responsibility productivity. However, the study between stress and academic productivity is very limited. Proper interventions are required to minimize stress at the workplace.

  10. Understanding student stress: a qualitative study of the stress experienced by third level students

    Aherne, Declan

    1998-01-01

    Stress can be understood in terms of the meaning of stressful experiences for individuals. The meaning of stressful experiences involves threats to self-adequacy, where self-adequacy is considered a basic human need. Appropriate research methods are required to explore this aspect of stress. The present study is a qualitative exploration of the stress experienced by a group of 27 students at the National Institute of Higher Education, Limerick (since renamed the University of Limerick). The s...

  11. Stressed out? Associations between perceived and physiological stress responses in adolescents: The TRAILS study

    Oldehinkel, Albertine J.; Ormel, Johan; Bosch, Nienke M.; Bouma, Esther M. C.; Van Roon, Arie M.; Rosmalen, Judith G. M.; Riese, Harriette

    2011-01-01

    Studies regarding the interrelation of perceived and physiological stress indices have shown diverging results. Using a population sample of adolescents (N=715, 50.9% girls, mean age 16.11 years, SD=0.59), we tested three hypotheses: (1) perceived responses during social stress covary with concurrent physiological stress responses; (2) high pretest levels of perceived stress predict large physiological responses; and (3) large physiological responses to social stress predict low posttest perc...

  12. Curcumin Mitigates Accelerated Aging after Irradiation in Drosophila by Reducing Oxidative Stress

    Ki Moon Seong

    2015-01-01

    Full Text Available Curcumin, belonging to a class of natural phenol compounds, has been extensively studied due to its antioxidative, anticancer, anti-inflammatory, and antineurodegenerative effects. Recently, it has been shown to exert dual activities after irradiation, radioprotection, and radiosensitization. Here, we investigated the protective effect of curcumin against radiation damage using D. melanogaster. Pretreatment with curcumin (100 μM recovered the shortened lifespan caused by irradiation and increased eclosion rate. Flies subjected to high-dose irradiation showed a mutant phenotype of outstretched wings, whereas curcumin pretreatment reduced incidence of the mutant phenotype. Protein carbonylation and formation of γH2Ax foci both increased following high-dose irradiation most likely due to generation of reactive oxygen species. Curcumin pretreatment reduced the amount of protein carbonylation as well as formation of γH2Ax foci. Therefore, we suggest that curcumin acts as an oxidative stress reducer as well as an effective protective agent against radiation damage.

  13. Nanoscale-alumina induces oxidative stress and accelerates amyloid beta (Aβ) production in ICR female mice

    Shah, Shahid Ali; Yoon, Gwang Ho; Ahmad, Ashfaq; Ullah, Faheem; Amin, Faiz Ul; Kim, Myeong Ok

    2015-09-01

    The adverse effects of nanoscale-alumina (Al2O3-NPs) have been previously demonstrated in both in vitro and in vivo studies, whereas little is known about their mechanism of neurotoxicity. It is the goal of this research to determine the toxic effects of nano-alumina on human neuroblastoma SH-SY5Y and mouse hippocampal HT22 cells in vitro and on ICR female mice in vivo. Nano-alumina displayed toxic effects on SH-SY5Y cell lines in three different concentrations also increased aluminium abundance and induced oxidative stress in HT22 cells. Nano-alumina peripherally administered to ICR female mice for three weeks increased brain aluminium and ROS production, disturbing brain energy homeostasis, and led to the impairment of hippocampus-dependent memory. Most importantly, these nano-particles induced Alzheimer disease (AD) neuropathology by enhancing the amyloidogenic pathway of Amyloid Beta (Aβ) production, aggregation and implied the progression of neurodegeneration in the cortex and hippocampus of these mice. In conclusion, these data demonstrate that nano-alumina is toxic to both cells and female mice and that prolonged exposure may heighten the chances of developing a neurodegenerative disease, such as AD.

  14. Plasma accelerators

    Recently attention has focused on charged particle acceleration in a plasma by a fast, large amplitude, longitudinal electron plasma wave. The plasma beat wave and plasma wakefield accelerators are two efficient ways of producing ultra-high accelerating gradients. Starting with the plasma beat wave accelerator (PBWA) and laser wakefield accelerator (LWFA) schemes and the plasma wakefield accelerator (PWFA) steady progress has been made in theory, simulations and experiments. Computations are presented for the study of LWFA. (author)

  15. Beam dynamics studies in a tesla positron pre-accelerator

    Moiseev, V A; Flöttmann, K

    2001-01-01

    The TESLA linear collider is based on superconducting accelerating cavities.Behind the positron production target normal conducting cavities have to be used in order to cope with high particle losses and with focusing solenoid surrounding the cavities.The main purpose of this pre-accelerator is to provide maximum capture efficiency for the useful part of the totally acceptable positron beam with technically reasonable parameters of the linac.The coupled optimization of the capture optics behind the target and pre-accelerator rf-operation has been carried out.The beam dynamics simulation results as well as the pre-accelerator peculiarities are presented.

  16. Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8.

    Sureda, Francesc X; Gutierrez-Cuesta, Javier; Romeu, Marta; Mulero, Miquel; Canudas, Anna Maria; Camins, Antoni; Mallol, Jordi; Pallàs, Mercè

    2006-04-01

    The senescence-accelerated strains of mice (SAMP) are well-characterized animal models of senescence. Senescence may be related to enhanced production or defective control of reactive oxygen species, which lead to neuronal damage. Therefore, the activity of various oxidative-stress related enzymes was determined in the cortex of 5 months-old senescence-accelerated mice prone-8 (SAMP-8) of both sexes and compared with senescence-accelerated mice-resistant-1 (SAMR-1). Glutathione reductase and peroxidase activities in SAMP-8 male mice were lower than in male SAMR-1, and a decreased catalase activity was found in both male and female SAMP-8 mice, which correlates with the lower catalase expression found by Western blotting. Nissl staining showed marked loss of neuronal cells in the cerebral cortex of five month-old SAMP-8 mice. SAMP-8 mice also had marked astrogliosis and microgliosis. We also found an increase in caspase-3 and calpain activity in the cortex. In addition, we observed morphological changes in the immunostaining of tau protein in SAMP-8, indicative of a loss of their structural function. Altogether, these results show that, at as early as 5 months of age, SAMP-8 mice have cytological and molecular alterations indicative of neurodegeneration in the cerebral cortex and suggestive of altered control of the production of oxidative species and hyper-activation of calcium-dependent enzymes. PMID:16542809

  17. Study on the ablation in railgun electromagnetic accelerators

    One of the possible applications of the railguns is the injection of the particles ranged 1-5 mm with the velocities of more that 2 km/s in the fusion reactor for the refueling and plasma diagnostics. Railguns in a range of square bore configurations 4x4-10x10 mm are studied to determine the influence of wall ablation on the macroparticles acceleration under the current up to 200 kA. Caprolon and fiberglass are used as insulators. The problems of the energy transfer from the discharge to an insulator and the problems of achieving velocities higher that 2km/s in the small bare railgun are discussed. 6 refs.; 5 figs

  18. Study on radiation sterilization of electron beam accelerator

    To study the effects of radiation sterilization of the electron beam, the three species of microorganisms, Escherichia. coli, Staphylococcus aureus and Proteus vulgaris were irradiated with the electron beam, delivered by the electron accelerator independently developed by the Institute of Modern Physics, Chinese Academy of Sciences, and the changes of superoxide dismutase (SOD) activity of these irradiated microorganisms were also tested. The results indicated that the Staphylococcus aureus were fully radio-sterilized with the radiation dosage of 2.0 kGy, but 2.2 kGy to the Escherichia. coli and Proteus vulgaris. Moreover, the data also demonstrated that the irradiation had noticeable effects on the SOD activity of the three microorganisms. (authors)

  19. Reliability studies of a high-power proton accelerator for accelerator-driven system applications for nuclear waste transmutation

    The main effort of the present study is to analyze the availability and reliability of a high-performance linac (linear accelerator) conceived for Accelerator-Driven Systems (ADS) purpose and to suggest recommendations, in order both to meet the high operability goals and to satisfy the safety requirements dictated by the reactor system. Reliability Block Diagrams (RBD) approach has been considered for system modelling, according to the present level of definition of the design: component failure modes are assessed in terms of Mean Time Between Failure (MTBF) and Mean Time To Repair (MTTR), reliability and availability figures are derived, applying the current reliability algorithms. The lack of a well-established component database has been pointed out as the main issue related to the accelerator reliability assessment. The results, affected by the conservative character of the study, show a high margin for the improvement in terms of accelerator reliability and availability figures prediction. The paper outlines the viable path towards the accelerator reliability and availability enhancement process and delineates the most proper strategies. The improvement in the reliability characteristics along this path is shown as well

  20. A STUDY ON APPLICABILITY OF GROUND RESPONSE ACCELERATION METHOD TO DEEP VERTICAL UNDERGROUND STRUCTURES

    Matsumoto, Mai; Shiba, Yukio; Watanabe, Kazuaki

    This paper discusses the applicability of ground response acceleration method to seismic analysis for deep vertical underground structures. To examine the applicability, an analysis of relationships between response of ground and the shaft was conducted. It was found from the analysis that vertical axial stress of the shaft was not correspond with shear stress of ground. Accordingly, it was concluded that the axial stress was not evaluated correctly by the existing method. Therefore, to extend the applicability of the method, ground responses correlated with the axial stress were analyzed and a new method using these ground responses was proposed.

  1. [Sugar consumption and prenatal acceleration. II. Studies on the etiology and pathophysiology of secular prenatal acceleration].

    Ziegler, E

    1976-12-01

    The pathophysiologic considerations support the causal relationship between the secular trend of sugar consumption in industrialized society and the development of prenatal acceleration, which is evident on the basis of epidemiological data. The excessive consumption of sugar and the other quickly absorbed "refined" carbohydrates enhances the hormonogenic effect of food which is also potentiated by the proteins. Together with the caloric overloading, provoked also by the excess in fat, characteristic for the affluent society, the excessive sugar consumption enhances in the pregnant women obesity and "protodiabetes" (PFEIFFER), in the predisposed child the tendency to hyperinsulinism with its consequences. In a prediabetic mother with normal glucose-tolerance the regularly repeated postprandial overfloating of the fetus with maternal glucose changes the feto-maternal hormonal regulation and enhances together with the overloading of substrate, i.e. energy and elements of biosyntheses, the accelerated fetal growth and especially the obesity of the large baby. PMID:1035212

  2. Study on the focusing properties of the accelerating tube

    An accelerating tube is an electrostatic lens system. The author made use of the micro unit model to derive the path equations of an accelerating tube by integrating the ion path of a unit electrostatic lens. The focusing properties are discussed according to the calculated results

  3. Accelerators for the study of many particle systems

    Alonso, J.R.

    1985-08-01

    Higher energy accelerators continue to play an important role in nuclear physics, probing ever more deeply into the properties and behavior of the constituents of nuclear matter. Three main projectile-types currently used are electrons, light hadrons (protons, mesons) and heavy ions; each addresses different aspects of the reaction process. Current and planned accelerators for each of these probes are discussed.

  4. Simulation Study of Laser Plasma Accelerator Via Vorpal

    Zhu, Xiongwei

    2015-01-01

    In this paper, we use PIC code Vorpal to do the extensive simulation about the laser plasma accelerator in the linear, quasilinear and nonlinear regime respectively. We design the ~100 MeV or so laser plasma accelerator ( LPA ) via Vorpal simulation. Finally, we discuss the application of the designed LPA in the compact light source field.

  5. Experimental study of ion heating and acceleration during magnetic reconnection

    Hsu, S.C.

    2000-01-28

    This dissertation reports an experimental study of ion heating and acceleration during magnetic reconnection, which is the annihilation and topological rearrangement of magnetic flux in a conductive plasma. Reconnection is invoked often to explain particle heating and acceleration in both laboratory and naturally occurring plasmas. However, a simultaneous account of reconnection and its associated energy conversion has been elusive due to the extreme inaccessibility of reconnection events, e.g. in the solar corona, the Earth's magnetosphere, or in fusion research plasmas. Experiments for this work were conducted on MRX (Magnetic Reconnection Experiment), which creates a plasma environment allowing the reconnection process to be isolated, reproduced, and diagnosed in detail. Key findings of this work are the identification of local ion heating during magnetic reconnection and the determination that non-classical effects must provide the heating mechanism. Measured ion flows are sub-Alfvenic and can provide only slight viscous heating, and classical ion-electron interactions can be neglected due to the very long energy equipartition time. The plasma resistivity in the reconnection layer is seen to be enhanced over the classical value, and the ion heating is observed to scale with the enhancement factor, suggesting a relationship between the magnetic energy dissipation mechanism and the ion heating mechanism. The observation of non-classical ion heating during reconnection has significant implications for understanding the role played by non-classical dissipation mechanisms in generating fast reconnection. The findings are relevant for many areas of space and laboratory plasma research, a prime example being the currently unsolved problem of solar coronal heating. In the process of performing this work, local measurements of ion temperature and flows in a well-characterized reconnection layer were obtained for the first time in either laboratory or observational

  6. Experimental study of ion heating and acceleration during magnetic reconnection

    This dissertation reports an experimental study of ion heating and acceleration during magnetic reconnection, which is the annihilation and topological rearrangement of magnetic flux in a conductive plasma. Reconnection is invoked often to explain particle heating and acceleration in both laboratory and naturally occurring plasmas. However, a simultaneous account of reconnection and its associated energy conversion has been elusive due to the extreme inaccessibility of reconnection events, e.g. in the solar corona, the Earth's magnetosphere, or in fusion research plasmas. Experiments for this work were conducted on MRX (Magnetic Reconnection Experiment), which creates a plasma environment allowing the reconnection process to be isolated, reproduced, and diagnosed in detail. Key findings of this work are the identification of local ion heating during magnetic reconnection and the determination that non-classical effects must provide the heating mechanism. Measured ion flows are sub-Alfvenic and can provide only slight viscous heating, and classical ion-electron interactions can be neglected due to the very long energy equipartition time. The plasma resistivity in the reconnection layer is seen to be enhanced over the classical value, and the ion heating is observed to scale with the enhancement factor, suggesting a relationship between the magnetic energy dissipation mechanism and the ion heating mechanism. The observation of non-classical ion heating during reconnection has significant implications for understanding the role played by non-classical dissipation mechanisms in generating fast reconnection. The findings are relevant for many areas of space and laboratory plasma research, a prime example being the currently unsolved problem of solar coronal heating. In the process of performing this work, local measurements of ion temperature and flows in a well-characterized reconnection layer were obtained for the first time in either laboratory or observational

  7. Studies of Coupled Cavity Linac (CCL) Accelerating Structures with 3-D Codes

    Spalek, G.; Christiansen, D. W.; Smith, P D; Greninger, P. T.; Charman, C. M.

    2000-01-01

    The cw CCL being designed for the Accelerator Production of Tritium (APT) project accelerates protons from 96MeV to 211MeV. It consists of 99 segments each containing up to seven accelerating cavities. Segments are coupled by intersegment coupling cavities and grouped into supermodules. The design method needs to address not only basic cavity sizing for a given coupling and pi/2 mode frequency, but also the effects of high power densities on the cavity frequency, mechanical stresses, and the ...

  8. Brief Treatment of Co-Occurring Post Traumatic Stress and Depressive Symptoms By Use of Accelerated Resolution Therapy (ART®

    Kevin eKip

    2013-03-01

    Full Text Available This uncontrolled prospective cohort study evaluated the use of Accelerated Resolution Therapy (ART for treatment of comorbid symptoms of post-traumatic stress disorder (PTSD and major depressive disorder (MDD. Twenty-eight adult subjects, mean age of 41 years (79% female, 36% Hispanic, received a mean of 3.7 + 1.1 ART treatment sessions (range 1-5. ART is a new exposure-based psychotherapy that makes use of eye movements. Subjects completed a range of self-report psychological measures before and after treatment with ART including the 17-item PCL-C checklist (symptoms of PTSD and 20-item Center for Epidemiologic Studies Depression Scale (CES-D. For the PCL-C, the pre-ART mean (+ standard deviation was 62.5 (8.8 with mean reductions of -29.6 (12.5, -30.1 (13.1, and -31.4 (14.04 at post-ART, 2-month, and 4-month follow up, respectively (p<0.0001 for comparisons to Pre-ART score. Compared to pre-ART status, this corresponded to standardized effect sizes of 2.37, 2.30, and 3.01, respectively. For the CES-D, the pre-ART mean was 35.1 (8.8 with mean reductions of -20.6 (11.0, -18.1 (11.5, and -15.6 (14.4 at post-ART, 2-month, and 4-month follow up, respectively (p<0.0001 compared to Pre-ART score. This corresponded to standardized effect sizes of 1.88, 1.58, and 1.09, respectively. Strong correlations were observed at 2-month and 4-month follow-up for post-treatment changes in PTSD and depression symptom scores (r=0.79, r=0.76, respectively, p<0.0002. No serious treatment-related adverse effects were reported. In summary, ART appears to be a promising brief, safe, and effective treatment for adults with clinically significant comorbid symptoms of PTSD and depression. Future controlled and mechanistic studies with this emerging therapy are warranted, particularly given its short treatment duration, and in light of current heightened emphasis on health care cost constraints.

  9. Antenatal stress: An Irish case study.

    Carolan-Olah, Mary

    2013-05-16

    BACKGROUND:: stress in pregnancy is common and impacts negatively on women, infants and families. A number of factors contribute to high levels of stress in pregnancy, including financial concerns, marital discord, low support systems and low socio-economic status. OBJECTIVES:: the aim of this study was to evaluate stress anxiety levels and depressive symptoms among low risk women in an area in Ireland that was particularly impacted by the 2008 economic crisis. DESIGN:: a quantitative descriptive cross-sectional design was used. Data were collected using the Edinburgh Postnatal Depression Scale (EPDS), the Perceived Stress Scale and the State Trait Anxiety Inventory (STAI). Data was collected at a single time during the second trimester. SETTING:: this paper reports a case study of one maternity service in Ireland. Participants included low risk pregnant women who were attending the hospital clinic for routine antenatal care. RESULTS:: of 150 questionnaires distributed, 74 completed questionnaires were returned indicating a 49.3% return rate. Findings indicated high levels of stress, anxiety and depressive symptomatology among participants. There were no significant difference in mean EPDS score for different age groups (F4,69=2.48, P=0.052), living arrangements (F4,68=0.90, P=0.5) or usual occupation (F4,69=1.45, P=0.2). A score of ≥12 was taken as indicative of probable antenatal depression and 86.5% of participants responded with a score of 12 or above. PSS scores were also high and more than three quarters of respondents scored ≥15 (75.6%) and more than a third had scores ≥20 (35.1%), out of a total score of 40. There was a significant difference in mean PSS score between the different age groups (F4,69=3.60, P=0.010) but not for living arrangements or usual occupation. A STAI score of ≥39 was taken as indicative of antenatal anxiety, and 74.3% of participants responded with a score of 39 or above. There were no significant differences in mean STAI

  10. A study on anti-stress property of Nardostachys jatamamsi on stress induced Drosophila melanogaster

    Shilpashree R.

    2011-09-01

    Full Text Available Stress is a feeling that’s created when we react to particular events. It s the body’s way of rising to a challenge and preparing to meet a tough situation with focus, strength, stamina, and heightened alertness. As a result of the stress immune system can be suppressed by chronic stress opening to increased infections and increasing the risk of autoimmune diseases. So one has to learn away to overcome stress. Here is an attempt made to overcome the stress induced in Drosophila melanogaster a model organism, in this study. Methotrexate is used to induce the stress at different concentration taking different group of flies and a Nardostachys jatamamsi plant extract having antistress property is used to relieve the stress induced. This stress relieve measured by the various stress related enzymes like catalase and Superoxide dismutase by this antistress property of the plant Nardostachys jatamamsi was shown.

  11. A study of diagnostics expert system for accelerator applications

    Knowledge based techniques are proving to be useful in a number of problem domains which typically requires human expertise. Expert systems employing knowledge based techniques are a recent product of artificial intelligence. Methods developed in the artificial intelligence area can be applied with success for certain classes of problems in accelerator. Accelerators are complex devices with thousands of components. The number of possible faults or problems that can appear is enormous. A diagnostics expert system can provide great help in finding and diagnosing problems in Indus-II accelerator sub-systems. (author)

  12. Clinical experimental stress studies: methods and assessment.

    Bali, Anjana; Jaggi, Amteshwar Singh

    2015-01-01

    Stress is a state of threatened homeostasis during which a variety of adaptive processes are activated to produce physiological and behavioral changes. Stress induction methods are pivotal for understanding these physiological or pathophysiological changes in the body in response to stress. Furthermore, these methods are also important for the development of novel pharmacological agents for stress management. The well-described methods to induce stress in humans include the cold pressor test, Trier Social Stress Test, Montreal Imaging Stress Task, Maastricht Acute Stress Test, CO2 challenge test, Stroop test, Paced Auditory Serial Addition Task, noise stress, and Mannheim Multicomponent Stress Test. Stress assessment in humans is done by measuring biochemical markers such as cortisol, cortisol awakening response, dexamethasone suppression test, salivary α-amylase, plasma/urinary norepinephrine, norepinephrine spillover rate, and interleukins. Physiological and behavioral changes such as galvanic skin response, heart rate variability, pupil size, and muscle and/or skin sympathetic nerve activity (microneurography) and cardiovascular parameters such as heart rate, blood pressure, and self-reported anxiety are also monitored to assess stress response. This present review describes these commonly employed methods to induce stress in humans along with stress assessment methods. PMID:26020552

  13. Study of spin resonances in the accelerators with snakes

    Spin resonances in the circular accelerators with snakes are studied to understand the nature of snake resonances. We analyze the effect of snake configuration, and the snake superperiod on the resonance. Defining the critical resonance strength ε/sub c/ as the maximum tolerable resonance strength without losing the beam polarization after passing through the resonance, we found that ε/sub c/ is a sensitive function of the snake configuration, the snake superperiod at the first order snake resonance, the higher order snake resonance conditions and the spin matching condition. Under properly designed snake configuration, the critical resonance strength ε/sub c/ is found to vary linearly with N/sub S/ as = (1/π)sin/sup /minus/1/(cos πν/sub z//sup /1/2//)N/sub S/, where ν/sub z/ and N/sub S/ are the betatron tune and the number of snakes respectively. We also study the effect of overlapping intrinsic and imperfection resonances. The imperfection resonance should be corrected to a magnitude of insignificance (e.g., ε≤0.1 for two snakes case) to maintain proper polarization. 23 refs., 25 figs

  14. Study of electron groupings in the Saclay linear accelerator

    The classical theory of the linear accelerator buncher does not fit the experimental measurements of the shape of the bunch of electrons performed at Saclay by the method of the energy spectrum. If the spurious effect of the mode converter at the input of the linac is taken into account the theory can fit the experimental results and also explain the variations of the phase of the bunch on the accelerating sine wave. (authors)

  15. Study and characteristics of a VIVITRON type electrostatic accelerator

    The conception of the 2 MV tandem electrostatic accelerator ARAMIS, which is intended for research in solid state and astrophysics, benefits from certain technological advances of the VIVITRON. Our study has dealt with the shape and arrangement of the column electrodes for this machine. We have employed the program Poisson which performs two-dimensional calculations of the electrical constraint at the surface of the conductors. The maximum field strength on the constrained regions has a value of 11.5 MV/m. This completely acceptable result let one expect that the machine operation will be satisfactory. Certain limitations inherent in the bidimensional calculations have led us to consider programs treating three dimensions. Access to the finite element library MODULEF at the Centre de Calcul in Strasbourg has increased the computational possibilities. The case of an insulating post in the coaxial terminal-tank structure has thus been treated. This work has allowed the construction of the column electrodes to proceed. They will be ready the beginning 1987. The tandem ARAMIS being built should be operational by the end of 1987

  16. Parametric study of the accelerator-driven transmutation system

    A couple of parametric studies were performed for an accelerator-driven transmutation system in KAERI (Korea Atomic Energy Research Institute). For the analysis, LAHET code system developed by LANL was employed. Molten salt fuel was adopted with its chemical composition of 64NaCl3-1Pu-35MA(Minor Actinide)Cl3. The isotope compositions of Pu and Ma were determined based on the composition in the 10-year cooled spent fuel having 3.2 W% initial enrichment and 33GWD/MTU discharge burnup. Proton beam of 20 mA, 1 GeV was assumed for the neutron production by the spallation reaction with the fuel. The fuel was designed to perform multifunction such as target, coolant. From the calculation results, one proton was believed to produce about 27 neutrons and the neutron multiplication factor was found to be 0.95 for the given system condition. For the beam of 20 mA, 1 GeV, the neutron flux reached up to 1.26x1015 n/cm2 and the corresponding total thermal power was 773 MWth. It was believed that the proposed system could transmute 502 kg of MA a year. 3 refs., 3 figs., 1 tab

  17. The SuperB Accelerator: Overview and Lattice Studies

    Biagini, M.E.; Boni, R.; Boscolo, M.; Drago, A.; Guiducci, S.; Preger, M.; Raimondi, P.; Tomassini, S.; Vaccarezza, C.; Zobov, M.; /Frascati; Cai, Y.; Fisher, A.; Heifets, S.; Novokhatski, A.; Pivi, M.T.; Seeman, J.; Sullivan, M.; Wienands, U.; /SLAC; Paoloni, E.; Marchiori, G.; /Pisa U.; Koop, I.; /Novosibirsk, IYF /Daresbury /LBL, Berkeley /CERN /Orsay, LAL /KEK, Tsukuba

    2011-11-22

    SuperB aims at the construction of a very high luminosity (10{sup 36} cm{sup -2} s{sup -1}) asymmetric e{sup +}e{sup -} Flavour Factory, with possible location at the campus of the University of Rome Tor Vergata, near the INFN Frascati National Laboratory. In this paper the basic principles of the design and details on the lattice are given. SuperB is a new machine that can exploit novel very promising design approaches: (1) large Piwinski angle scheme will allow for peak luminosity of the order of 10{sup 36} cm{sup -2} s{sup -1}, well beyond the current state-of-the-art, without a significant increase in beam currents or shorter bunch lengths; (2) 'crab waist' sextupoles will be used for suppression of dangerous resonances; (3) the low beam currents design presents reduced detector and background problems, and affordable operating costs; (4) a polarized electron beam can produce polarized {tau} leptons, opening an entirely new realm of exploration in lepton flavor physics. SuperB studies are already proving useful to the accelerator and particle physics communities. The principle of operation is being tested at DAFNE. The baseline lattice, based on the reuse of all PEP-II hardware, fits in the Tor Vergata University campus site, near Frascati. A CDR is being reviewed by an International Review Committee, chaired by J. Dainton (UK). A Technical Design Report will be prepared to be ready by beginning of 2010.

  18. Experimental study of proton acceleration with ultra-high intensity, high contrast laser beam

    This thesis reports experimental work in the domain of laser-matter interaction to study the production of energetic proton beams. The ion beams accelerated by laser have been increasing in quality, in energy and in repeatability as laser technology keeps improving. The presence of the pedestal before the high peak laser pulse introduces many unknowns in the accelerating conditions that are created on the front and on the rear surface of the target. The first part of the experimental activities is focused to a better comprehension and the experimental validation of the interaction of a 'pedestal-like', moderate intensity, laser pulse on Aluminum targets. The developed interferometric technique proved to be reliable and produced a complete set of maps of the early stages of the plasma expansion. The reflectometry experiment stresses the importance of the quality of the metallic targets and underlines some obscure points on the behaviour of the rear surface of the illuminated foil. For instance the reflectometry measurements on the thicker targets are significantly different from what is foreseen by the simulations about the timescale of the shock break out. In the second part, the XPW laser pulse is used in ion acceleration from thin metal foils. The laser and target parameters are varied to put in evidence the dependence of the ion beam to the experimental condition. In conclusion I can say that first, during the variation of the target thickness, an optimum is put in evidence. Secondly, the correlation between the laser pulse duration and the proton cutoff energy is qualitatively different between thicker (15 μm) and thinner (1.5 μm, 3 μm) targets. For the first, an optimal pulse duration exists while for the seconds, no variation is found - in the searched space - from the monotonic decreasing of the cutoff energy with the peak intensity. The experimental results put however in evidence some points that are not completely understood. (A.C.)

  19. Electron accelerator for radiation sterilization and R and D study

    Upgrading of radiation facility located at Institute of Nuclear Chemistry and Technology in Warsaw has been initiated, with support of IAEA TC Project, towards higher technical and economical effectiveness, better operational characteristics suitable for radiation processing and research programs in order to promote in Poland the radiation technologies for sterilization medical devices and tissue grafts as well as food product hygenization and other radiation processes where high energy electrons are required. The objective of the project is 10 MeV, 15 kW linear electron accelerator equipped with microwave source based on modern klystron device TH2158 operated at frequency 2856 MHz and standing wave accelerating section. The following stages of the project have been described: electron gun construction, design of microwave system of accelerator including pulse power supply, completion and installation of necessary systems including klystron stand, pulse power supply stand, driving generator stand and waveguide system. The klystron modulator was designed with high power semiconductor HV transistor. Electron beam alignment, beam parameters evaluation and accelerator commissioning are foreseen in the final stage of the project. The better accelerator availability, more stable beam parameters, better spare parts availability, reduced exploitation costs and higher beam power are expected after successful project implementation. Implementation of the project will provide opportunity to develop skills and knowledge of the personnel engaged. It will make also possible to apply the results to another facility in Poland and other central European countries. (author)

  20. An Overview of the Study on Stress Magnitude

    Sheng Shuzhong; Wan Yongge

    2009-01-01

    Crustal stress field holds an important position in geodynamics research, such as in plate motion simulations, uplift of the Qinghai-Xizang (Tibet) Plateau and earthquake preparation and occurrence. However, most of the crustal stress studies emphasize particularly on the determination of stress direction, with little study being done on stress magnitude at present. After reviewing ideas on a stress magnitude study from geological, geophysical and various other aspects, a method to estimate the stress magnitude in the source region according to the deflection of stress direction before and after large earthquakes and the stress drop tensor of earthquake rupture has been developed. The proposed method can also be supplemented by the average apparent stress before and after large earthquakes. The stress direction deflection before and after large earthquakes can be inverted by massive focal mechanisms of foreshocks and aftershocks and the stress drop field generated by the seismic source can be calculated by the detailed distribution of the earthquake's rupture. The mathematical relationship can then be constructed between the stress drop field, where its magnitude and direction are known and the stress tensor before and after large earthquakes, where its direction is known but magnitude is unknown, thereby obtaining the stress magnitude. The average apparent stress before and after large earthquakes can be obtained by using the catalog of broadband radiated energy and seismic moment tensor of foreshocks and aftershocks and the different responses to stress drops. This relationship leads to another estimation of stress magnitude before a large earthquake. The stress magnitude and its error are constrained by combining the two methods, which provide new constraints for the geodyuamics study.

  1. A study of neutron output from a medical linear accelerator

    In recent years, medical linear accelerators of higher energies (E>10 MeV) are becoming of common use in Brazil and the National Nuclear Energy Commission (CNEN) is facing the problem of licensing these Radiative Facilities. The question of how to shield these rooms, considering the neutron output from these machines, is not trivial. Many empirical models suggest how to calculate the neutron dose equivalent due to these particles, which are mainly produced trough (g,n) reactions in the accelerator head. In this article we present some measurements of neutrons produced by a 18 MeV Varian CLINAC 2100C linear accelerator at the Albert Einstein Hospital, in Sao Paulo, Brazil. The results are compared with theoretical calculations based on empirical models as well as on the equations presented in NCRP 79. (author)

  2. Beam dynamics studies of the Heavy Ion Fusion Accelerator injector

    A driver-scale injector for the Heavy Ion Fusion Accelerator project has been built at LBL. This machine has exceeded the design goals of high voltage (> 2 MV), high current (> 0.8 A of K+) and low normalized emittance (< 1 π mm-mr). The injector consists of a 750 keV diode pre-injector followed by an electrostatic quadrupole accelerator (ESQ) which provides strong (alternating gradient) focusing for the space-charge dominated beam and simultaneously accelerates the ions to 2 MeV. The fully 3-D PIC code WARP together with EGUN and POISSON were used to design the machine and analyze measurements of voltage, current and phase space distributions. A comparison between beam dynamics characteristics as measured for the injector and corresponding computer calculations will be presented

  3. Transformer ratio studies for single bunch plasma wakefield acceleration

    In Plasma Wakefield Acceleration (PWFA) plasma oscillations are driven by ultra relativistic electron beams. The ratio of the maximum accelerating field behind the driving beam (bunch) and the maximum decelerating field inside the driving beam (bunch) is defined as Transformer Ratio, a key parameter that determines the energy gain in particle acceleration. We investigate the transformer ratio for different shapes of a single driving bunch. One dimensional, fluid, relativistic, cold plasma equations have been numerically solved. A complete map of the transformer ratio is obtained by varying: bunch shape, bunch length and density ratio. It is found that the transformer ratio critically depends on the bunch shape and on the density ratio. Moreover both in the linear as well as in the non-linear regime the theoretical limit of 2 for the transformer ratio of a single symmetric bunch can be exceeded using asymmetric bunches in the linear regime as well as symmetric bunches in nonlinear regime

  4. Occupational stress :a study of stress levels as perceived by selected employees related to situational and dispositional stress

    Jones, Kenneth D.

    1992-01-01

    Evidence from studies related to the workplace (Ziemenski, 1981 and Knautz, 1982) suggest that occupational stress is a causal factor in job-related illnesses such as coronary heart disease, psychoneurotic and personality disorders, and migraine headaches. II In addition to physiological problems resulting from stress almost every psychosocial variable of importance is affected by stress in the workplace, including productivity, morale, and the .psychological well-bein...

  5. Correlation Studies of Trehalose with Oxidative Stress in Ethanol Stressed Yeast Pachysolen tannophilus

    R.K. Saharan; S C Sharma

    2010-01-01

    The aim of the study was to investigate the role of trehalose in ethanol induced oxidative stress condition in yeast Pachysolen tannophilus. The laboratory experiments were carried out during 2009 and 2010 at the Yeast Stress Response Study Laboratory of Biochemistry Department in Panjab University at Chandigarh, India. R esistance of the yeast Pachysolen tannophilus to ethanol stress was studied under 10% (v/v) ethanol concentrations for different time periods (0, 60 and 120 min). After trea...

  6. Mechanical stability study for Integrable Optics Test Accelerator at Fermilab

    McGee, M. W.; Andrews, R; Carlson, K.; Leibfritz, J.; Nobrega, L.; Valishev, A.

    2016-01-01

    The Integrable Optics Test Accelerator (IOTA) is proposed for operation at Fermilab. The goal of IOTA is to create practical nonlinear accelerator focusing systems with a large frequency spread and stable particle motion. The IOTA is a 40 m circumference, 150 MeV (e-), 2.5 MeV (p+) diagnostic test ring. A heavy low frequency steel floor girder is proposed as the primary tier for IOTA device component support. Two design lengths; (8) 3.96 m and (2) 3.1 m long girders with identical cross secti...

  7. SOURCES OF ACADEMIC STRESS – A STUDY ON MANAGEMENT STUDENTS

    Purna Prabhakar Nandamuri; Gowthami Ch

    2011-01-01

    The objective of this study is to explore the components of academic stress amongthe post graduate management students. Academic stress among students has long beenresearched on, and researchers have identified different stressors. The study further tries tomake an in-depth investigation into each component of academic stress such as curriculum andinstruction, team work related issues, assessment, and placement, to identify the micro issuesthat are causing stress. Around twelve micro issues h...

  8. Stress in medical students: A cross sectional study

    Chauhan, Hiteshkumar Muktilal; Shah, Hirendra R; Chauhan, Sumitraben Hiteshkumar; Chaudhary, Sucheta M

    2014-01-01

    Background & Objectives: Stress occurs when pressure is greater than resources available. Medical education has many factors causing stress among the medical students. This study was conducted to find out the prevalence of stress among medical students and to know the factors causing stress in them.Methods: This is a cross sectional study, conducted on the Ist MBBS to III/IInd MBBS students of B. J. Medical College, Ahmedabad, using a semistructured self administered questionnaire, in Oct...

  9. Calculation of mechanical stresses and deformations in superconducting magnets of the accelerating-storage complex

    To provide working capacity of superconducting magnets, mechanical stresses and deformations in the superconducting coil and tyre under conditions maximally approaching the practical ones are calculated. Calculations are carried out for the following processes: construction deformation under the effect of ponderomotive forces corresponding to the 50 kGs magnetic field in the centre; coil compression by a press; welding in points; magnet cooling till helium tempe-- rature. It is shown that the tyre thickness should be not less than 2.5 cm to prevent changes in the coil shape. The maximum press loading should be 3150 kg/cm2. The numerical values of deviations of coordinates of some boundary points of the coil from the optimum values at additional press compression are given

  10. Using optical lines to study particle acceleration at supernova remnants

    Morlino, Giovanni [APC, AstroParticule et Cosmologie, Université Paris Diderot, CNRS/IN2P3, CEA/Irfu, Observatoire de Paris, Sorbonne Paris Cité, 10, rue Alice Domon et Léonie Duquet, F-75205 Paris Cedex 13 (France); Department of Physics and Astronomy, Purdue University, 525 Northwestern Avenue, West Lafayette, IN 47907-2036 (United States)

    2014-11-15

    The shocks of several young supernova remnants (SNR) are often associated with very thin optical filaments dominated by Balmer emission resulting from charge-exchange and collisional excitation between neutral Hydrogen from the interstellar medium and shocked protons and electrons. Optical lines are a direct probe of the conditions at the shock, in particular the width of the narrow and broad components reflect the temperature upstream and downstream of the shock, respectively. When the shock accelerate efficiently non-thermal particles, the shock structure changes producing anomalous Balmer lines and it is possible to use their line shape and their spatial profile to check the efficiency of SNR shocks in accelerating cosmic rays. Here we illustrate the kinetic theory of shock acceleration in presence of neutrals with some applications to young SNRs. We show that in three cases (RCW 86, SNR 0509-67.5 and Tycho) anomalous Balmer lines can be explained assuming that a fraction of ∼ 10% of the total shock kinetic energy is converted into not thermal particles, while in one single case, the northwestern part of SN 1006, there is no evidence of efficient acceleration.

  11. The stress connection : neuroimaging studies of emotion circuits in social stress, personality, and stress-related psychopathology

    Veer, Ilya Milos

    2015-01-01

    The aim of this thesis was to identify the neural mechanisms that enable a person to adaptively respond to, and recover from stress, which was studied in healthy controls, in people with increased vulnerability or resilience to stress-related disorders, and in people with depression or PTSD, using m

  12. Design study of double-layer beam trajectory accelerator based on the Rhodotron structure

    Jabbari, Iraj; Poursaleh, Ali Mohammad; Khalafi, Hossein

    2016-08-01

    In this paper, the conceptual design of a new structure of industrial electron accelerator based on the Rhodotron accelerator is presented and its properties are compared with those of Rhodotron-TT200 accelerator. The main goal of this study was to reduce the power of RF system of accelerator at the same output electron beam energy. The main difference between the new accelerator structure with the Rhodotron accelerator is the length of the coaxial cavity that is equal to the wavelength at the resonant frequency. Also two sets of bending magnets were used around the acceleration cavity in two layers. In the new structure, the beam crosses several times in the coaxial cavity by the bending magnets around the cavity at the first layer and then is transferred to the second layer using the central bending magnet. The acceleration process in the second layer is similar to the first layer. Hence, the energy of the electron beam will be doubled. The electrical power consumption of the RF system and magnet system were calculated and simulated for the new accelerator structure and TT200. Comparing the calculated and simulated results of the TT200 with those of experimental results revealed good agreement. The results showed that the overall electrical power consumption of the new accelerator structure was less than that of the TT200 at the same energy and power of the electron beam. As such, the electrical efficiency of the new structure was improved.

  13. Feasibility study on the construction and utilization of charged particle accelerators

    This is a report on the thorough studies of feasible accelerator to be constructed in Korea from various aspects. By following the brief descriptions on the operational principles and applications of various types of particle accelerators, estimations of required budgeting for construction and operation of those accelerators are given in detail. From the forecasted availability of government investment to accelerator project and also from the expected great role of accelerators to be played for nuclear power developments, we draw three steps' development program of accelerator technology in Korea. The first step is mainly aimed to user development and accumulation of accelerator technology through the construction and utilization of 50-100MeV electron linear accelerator. The second step to be recommended is the construction of 20-30MeV proton linear accelerator which can be used as an injector for future proton synchrotron. The third step is construction and utilization of several GeV proton synchrotron. However, development of accelerator technology in advanced countries is so fast that above-mentioned second and third step may not be regarded to be definite plans

  14. Materials surfaces studies using cyclotron accelerated 14 N

    As part of Cyclotron Laboratory efforts to broaden the range of nuclear methods' applications to materials science using various charged particles, nitrogen-14 has been accelerated using the subharmonic regime (10-14 MeV for 14 N 3+ at 11,300 - 13,000 k Hz and B = 11.5 - 13.3 kGs). Results concerning the RBS characterization of metallic glass multilayer structures and Ni - Cr alloys using 14 N ions are presented. A comparison between RBS method performances using alpha particles and nitrogen-14 ions accelerated at the IPNE Cyclotron is also made. Possible new uses of 14 N ion beams, especially in metallic surface treatment, are discussed. (Author)

  15. Optical fiber feasibility study in Accelerated Pavement Testing facility

    Bueche, N.; Rychen, P.; Dumont, A.-G.; Santagata, E.

    2009-01-01

    The presented research has been carried out within the European project Intelligent Roads (INTRO). The major objective followed was to assess the potential of optical fiber for pavement monitoring in comparison with classical strain gauges. Thus, both measurement devices have been tested under the same conditions in a full scale Accelerated Pavement Testing (APT) at LAVOC. This facility allows the user to control different parameters such as loading configuration and temperature and, as a mat...

  16. Young Supernovae as Experimental Sites to Study Electron Acceleration Mechanism

    Maeda, Keiichi

    2012-01-01

    Radio emissions from young supernovae (~ 1 year after the explosion) show a peculiar feature in the relativistic electron population at a shock wave, where their energy distribution is steeper than typically found in supernova remnants (SNRs) and than the prediction from the standard diffusive shock acceleration (DSA) mechanism. This is especially established for a class of stripped envelope supernovae (SNe IIb/Ib/Ic) where a combination of high shock velocity and low circumstellar material (...

  17. Design study of an accelerator for heavy ion fusion

    Design of a demonstration accelerator for heavy ion fusion based on a synchrotron system is briefly described. The proposed complex system of injector linac, rapid cycling synchrotron and five accumulation rings can produce a peak current 1.6 kA, peak power 32 TW and total energy 0.3 MJ. Investigations of the intrabeam scattering give a lifetime of the beam longer than the fusion cycle time of 1 sec

  18. A Provisional Study of ADS Within Turkic Accelerator Complex Project

    Arik, M; Caliskan, A; Cetiner, M A; Sultansoy, S

    2012-01-01

    The Turkic Accelerator Complex (TAC) project has been developed with the support of the Turkish State Planning Organization by the collaboration of 10 Turkish universities. The complex is planned to have four main facilities, namely: SASE FEL Facility Based on 1 GeV Electron Linac, Third Generation Synchrotron Radiation Facility (SR) Based on 3.56 GeV Positron Synchrotron, Super-Charm Factory ($\\sqrt{s} = 3.77$ GeV) by colliding the electron beam coming from the linac with an energy of 1 GeV and positron beam coming through the positron ring with an energy of 3.56 GeV, GeV scale proton accelerator. Later has two-fold goal: Neutron Spallation Source (NSS) and ADS. The proton accelerator construction will have 3 MeV, 100 MeV, and 1 GeV phases. The technical design report is planned to be finished in 2013. Since Turkey has essential Thorium reserves the ADS becomes very attractive for our country as emerging energy technology.

  19. A STUDY OF OXIDATIVE STRESS IN DIABETES

    Babu Rao

    2015-06-01

    Full Text Available Non - enzymatic free radical mediated oxidation of biological molecules, membranes and tissues is associated with a variety of pathological events such as cancer, aging and diabetes mellitus . [1] Increased oxidative stress is seen in both types of diabetes me llitus namely type 1 and type 2, irrespective of duration, complications and treatment. In diabetes mellitus, oxidative stress seems primarily due to both an increased plasma free radical concentration and a sharp decline in antioxidant defences . [1] Among the causes of enhanced free radical production, hyperglycemia and hyper insulinemia seem to play a major role , [2,3] Hyperglycemia is the more easily modifiable factor among the two and good glycemic control can reduce the oxidative stress. Controversy pers ists regarding the other possible mechanisms of increased oxidative stress in diabetes and whether oxidative stress normalizes with adequate metabolic control alone. The role of oxidative stress and diabetic complications has been extensively investigated. Oxidative stress has been suggested to be involved in the genesis of both macro and micro angiopathy [4,5] Prospective trials are now underway addressing the controversial issues of possible role of pharmacological antioxidants in preventing or at least de laying the onset of diabetic complications.

  20. Translucent tissue defect in potato (Solanum tuberosum L.) tubers is associated with oxidative stress accompanying an accelerated aging phenotype.

    Zommick, Daniel H; Kumar, G N Mohan; Knowles, Lisa O; Knowles, N Richard

    2013-12-01

    Translucent tissue defect (TTD) is an undesirable postharvest disorder of potato tubers characterized by the development of random pockets of semi-transparent tissue containing high concentrations of reducing sugars. Translucent areas turn dark during frying due to the Maillard reaction. The newly released cultivar, Premier Russet, is highly resistant to low temperature sweetening, but susceptible to TTD. Symptoms appeared as early as 170 days after harvest and worsened with time in storage (4-9 °C, 95 % RH). In addition to higher concentrations of glucose, fructose and sucrose, TTD resulted in lower dry matter, higher specific activities of starch phosphorylase and glc-6-phosphate dehydrogenase, higher protease activity, loss of protein, and increased concentrations of free amino acids (esp. asparagine and glutamine). The mechanism of TTD is unknown; however, the disorder has similarities with the irreversible senescent sweetening that occurs in tubers during long-term storage, where much of the decline in quality is a consequence of progressive increases in oxidative stress with advancing age. The respiration rate of non-TTD 'Premier Russet' tubers was inherently higher (ca. 40 %) than that of 'Russet Burbank' tubers (a non-TTD cultivar). Moreover, translucent tissue from 'Premier Russet' tubers had a 1.9-fold higher respiration rate than the average of non-translucent tissue and tissue from non-TTD tubers. Peroxidation of membrane lipids during TTD development resulted in increased levels of malondialdehyde and likely contributed to a measurable increase in membrane permeability. Superoxide dismutase and catalase activities and the ratio of oxidized to total glutathione were substantially higher in translucent tissue. TTD tubers also contained twofold less ascorbate than non-TTD tubers. TTD appears to be a consequence of oxidative stress associated with accelerated aging of 'Premier Russet' tubers. PMID:24037414

  1. CFD study of flow accelerated corrosion in 3D elbows

    Highlights: • Calculated the MTC effects under the FAC operating conditions of Indian power plant. • The validation of MTC results with the experimental data of NPP has been carried out. • The vortical flow behavior is captured in terms of vortex corelines. • The close proximity effect is analyzed. • These results will help to developing the targeted inspection plans of failures. - Abstract: The objective of this paper is to examine the last step of the mechanistic model of wall thinning degradation mechanism i.e., convective mass transfer in feeder pipes under different environments of nuclear power plants (NPP). In the present study, the flow and mass transfer of demineralised water in carbon steel pipes such as single and double elbow was simulated under Indian NPP feeder water system conditions. The numerical simulations of mass transfer results are compared with the wall thickness measurement data of feeder pipes of Indian and CANDU NPP. The eddy structures and their interactions with the wall and the formation of vortex corelines were examined to analyze the flow changes in double elbow pipe. These vortex corelines appeared at the downstream of the bends. The intensity of these vortex corelines has been calculated by plotting the helicity along the vortex coreline. Due to the formation of vortex corelines and resulting flow changes, the mass transfer coefficient (MTC) varies circumferentially. MTC is the most important parameter to predict the highly susceptible FAC locations. For the MTC analysis, the Chilton–Colburn analogy in terms of wall shear stress was used. From this analogy, the effecting behavior of flow and geometrical parameters such as Reynolds number (Re) and the close proximity of bends, respectively, on MTC are studied. The locations of maximum MTC are calculated for both the single elbow of 73° and 90° and the double elbow of 90° and are shown in terms of contours. The flow singularity exists at the elbows; specifically in the

  2. A STUDY OF OXIDATIVE STRESS IN DIABETES

    Babu Rao; Santhoshi; Sridhar V; Souris; Der, Margaret

    2015-01-01

    Non - enzymatic free radical mediated oxidation of biological molecules, membranes and tissues is associated with a variety of pathological events such as cancer, aging and diabetes mellitus . [1] Increased oxidative stress is seen in both types of diabetes me llitus namely type 1 and type 2, irrespective of duration, complications and treatment. In diabetes mellitus, oxidative stress seems primarily due to both an increased plasma free radical concentra...

  3. Stress 'deafness' in a language with fixed word stress: an ERP study on Polish

    Ulrike eDomahs

    2012-11-01

    Full Text Available The aim of the present contribution was to examine the factors influencing the prosodic processing in a language with predictable word stress. For Polish, a language with fixed penultimate stress but several well-defined exceptions, difficulties in the processing and representation of prosodic information have been reported (e.g., Peperkamp & Dupoux, 2002. The present study utilized event-related potentials (ERPs to investigate the factors influencing prosodic processing in Polish. These factors are i the predictability of stress and ii the prosodic structure in terms of metrical feet. Polish native speakers were presented with correctly and incorrectly stressed Polish words and instructed to judge the correctness of the perceived stress patterns. For each stress violation an early negativity was found which was interpreted as reflection of an error-detection mechanism, and in addition exceptional stress patterns (= antepenultimate stress and post-lexical (= initial stress evoked a task-related positivity effect (P300 whose amplitude and latency is correlated with the degree of anomaly and deviation from an expectation. Violations involving the default (= penultimate stress in contrast did not produce such an effect. This asymmetrical result is interpreted to reflect that Polish native speakers are less sensitive to the default pattern than to the exceptional or post-lexical patterns. Behavioral results are orthogonal to the electrophysiological results showing that Polish speakers had difficulties to reject any kind of stress violation. Thus, on a meta-linguistic level Polish speakers appeared to be stress-‘deaf’ for any kind of stress manipulation, whereas the neural reactions differentiate between the default and lexicalized patterns.

  4. Accelerated adhesion of grafted skin by laser-induced stress wave-based gene transfer of hepatocyte growth factor

    Aizawa, Kazuya; Sato, Shunichi; Terakawa, Mitsuhiro; Saitoh, Daizoh; Tsuda, Hitoshi; Ashida, Hiroshi; Obara, Minoru

    2009-11-01

    Gene therapy using wound healing-associated growth factor gene has received much attention as a new strategy for improving the outcome of tissue transplantation. We delivered plasmid DNA coding for human hepatocyte growth factor (hHGF) to rat free skin grafts by the use of laser-induced stress waves (LISWs); autografting was performed with the grafts. Systematic analysis was conducted to evaluate the adhesion properties of the grafted tissue; angiogenesis, cell proliferation, and reepithelialization were assessed by immunohistochemistry, and reperfusion was measured by laser Doppler imaging as a function of time after grafting. Both the level of angiogenesis on day 3 after grafting and the increased ratio of blood flow on day 4 to that on day 3 were significantly higher than those in five control groups: grafting with hHGF gene injection alone, grafting with control plasmid vector injection alone, grafting with LISW application alone, grafting with LISW application after control plasmid vector injection, and normal grafting. Reepithelialization was almost completed on day 7 even at the center of the graft with LISW application after hHGF gene injection, while it was not for the grafts of the five control groups. These findings demonstrate the validity of our LISW-based HGF gene transfection to accelerate the adhesion of grafted skins.

  5. Crane RF accelerator for high current radiation damage studies

    An electron accelerator was designed and built for the Naval Weapons Support Center for transient radiation effects on electronics experiments and testing. The Crane L Band RF Electron Linac was designed to provide high currents over a wide range of pulse widths and energies. The energy extends to 60 MeV and pulse widths vary from a few ns to 10 μsec. Beam currents range from 20 amps in the short pulse case to 1.5 amps in the long pulse case. This paper describes the linac, its architecture, the e-gun and pulser, waveguides, klystrons and modulator, vacuum system, beam transport, and control systems. fig., tab

  6. Status of 3-body studies at the Saskatchewan Accelerator Laboratory

    The Accelerator Laboratory at the University of Saskatchewan is in the midst of a major update that will convert our conventional 300 MeV linac to a high duty factor machine with a high quality extracted electron beam. Since the initial proposals for the use of this new facility have been predominantly concerned with photon and electron induced reactions in light nuclei, I thought it appropriate to quickly review the present status, mention a few of the proposed experiments that are relevant to this symposium and summarize the experimental equipment that has been approved for the upgraded facility. (orig.)

  7. A quantitative scintigraphic study of stress fractures

    Multi-phase skeletal scintigraphy as employed in the investigation of stress fractures in 63 patients, mainly military recruits. 128 stress lesions, including stress fractures, shin splints, muscle trauma, joint lesions and enteropathies were seen in 60 patients. Ninety five stress fractures were identified in 55 patients of which 15 lesions were asymptomatic. Multiple stress fractures occurred in 29 of these patients. The tibia was the bone most frequently involved, (n=73), while the femur, fibula and feet showed a much less incidence (n=8,6,6 respectively), with only one metatarsal lesion. This distribution pattern was different from other reported series. Classification of diaphyseal stress fractures on the basis of percentage width involvement of the shaft showed 28 class II lesion (20-40%), 18 class III (41-60%), 15 class IV (61-80%) and 17 class V lesions (81-100%). No class I lesion 0-20%) was identified. Quantitation of all phases, i.e. the blood flow image (BFI, 0.60 sec), the early tissue phase image (ETI, 2-3 min), the late tissue phase image (LTI 5-6 min) and the delayed bone scan (BS-2 hr), was performed and lesion to normal ratios calculated. Statistical analysis showed a significant positive linear correlation between the width of the lesion and each of its BFI, ETI, LTI and BS ratios respectively. The BS ratio (means) progressively increased with the increase in class, and the difference in the mean values between adjacent classes was significant. In the light of this quantitative and statistical analysis, a modified quantitative classification system was proposed to include 3 groups of minor, intermediate and major stress fractures based on the interactive consideration of width and metabolic actively of the lesion

  8. Stressed out? Associations between perceived and physiological stress responses in adolescents : The TRAILS study

    Oldehinkel, Albertine J.; Ormel, Johan; Bosch, Nienke M.; Bouma, Esther M. C.; Van Roon, Arie M.; Rosmalen, Judith G. M.; Riese, Harriette

    2011-01-01

    Studies regarding the interrelation of perceived and physiological stress indices have shown diverging results. Using a population sample of adolescents (N=715, 50.9% girls, mean age 16.11 years, SD=0.59), we tested three hypotheses: (1) perceived responses during social stress covary with concurren

  9. A study of light ion accelerators for cancer treatment

    Prelec, K.

    1997-07-01

    This review addresses several issues, such as possible advantages of light ion therapy compared to protons and conventional radiation, the complexity of such a system and its possible adaptation to a hospital environment, and the question of cost-effectiveness compared to other modalities for cancer treatment or to other life saving procedures. Characteristics and effects of different types of radiation on cells and organisms will be briefly described; this will include conventional radiation, protons and light ions. The status of proton and light ion cancer therapy will then be described, with more emphasis on the latter; on the basis of existing experience the criteria for the use of light ions will be listed and areas of possible medical applications suggested. Requirements and parameters of ion beams for cancer treatment will then be defined, including ion species, energy and intensity, as well as parameters of the beam when delivered to the target (scanning, time structure, energy spread). Possible accelerator designs for light ions will be considered, including linear accelerators, cyclotrons and synchrotrons and their basic features given; this will be followed by a review of existing and planned facilities for light ions. On the basis of these considerations a tentative design for a dedicated light ion facility will be suggested, a facility that would be hospital based, satisfying the clinical requirements, simple to operate and reliable, concluding with its cost-effectiveness in comparison with other modalities for treatment of cancer.

  10. Beam Loss Calibration Studies for High Energy Proton Accelerators

    Stockner, M

    2007-01-01

    CERN's Large Hadron Collider (LHC) is a proton collider with injection energy of 450 GeV and collision energy of 7 TeV. Superconducting magnets keep the particles circulating in two counter rotating beams, which cross each other at the Interaction Points (IP). Those complex magnets have been designed to contain both beams in one yoke within a cryostat. An unprecedented amount of energy will be stored in the circulating beams and in the magnet system. The LHC outperforms other existing accelerators in its maximum beam energy by a factor of 7 and in its beam intensity by a factor of 23. Even a loss of a small fraction of the beam particles may cause the transition from the superconducting to the normal conducting state of the coil or cause physical damage to machine components. The unique combination of these extreme beam parameters and the highly advanced superconducting technology has the consequence that the LHC needs a more efficient beam cleaning and beam loss measurement system than previous accelerators....

  11. A study of light ion accelerators for cancer treatment

    This review addresses several issues, such as possible advantages of light ion therapy compared to protons and conventional radiation, the complexity of such a system and its possible adaptation to a hospital environment, and the question of cost-effectiveness compared to other modalities for cancer treatment or to other life saving procedures. Characteristics and effects of different types of radiation on cells and organisms will be briefly described; this will include conventional radiation, protons and light ions. The status of proton and light ion cancer therapy will then be described, with more emphasis on the latter; on the basis of existing experience the criteria for the use of light ions will be listed and areas of possible medical applications suggested. Requirements and parameters of ion beams for cancer treatment will then be defined, including ion species, energy and intensity, as well as parameters of the beam when delivered to the target (scanning, time structure, energy spread). Possible accelerator designs for light ions will be considered, including linear accelerators, cyclotrons and synchrotrons and their basic features given; this will be followed by a review of existing and planned facilities for light ions. On the basis of these considerations a tentative design for a dedicated light ion facility will be suggested, a facility that would be hospital based, satisfying the clinical requirements, simple to operate and reliable, concluding with its cost-effectiveness in comparison with other modalities for treatment of cancer

  12. Beam Dynamics Studies for a Laser Acceleration Experiment

    Spencer, James; Noble, Robert; Palmer, Dennis T; Siemann, Robert

    2005-01-01

    The NLC Test Accelerator at SLAC was built to address various beam dynamics issues for the Next Linear Collider. An S-Band RF gun, originally proposed for the NLCTA, is being installed together with a large-angle extraction line at 60 MeV. This is followed by a matching section, final focus and buncher for the laser acceleration experiment, E163. The laser-electron interaction area is followed by a broad range, high resolution spectrometer (HES) for electron bunch analysis. The RF gun is discussed in another paper. We discuss only the beam dynamics and high resolution analysis system at 6 MeV based on using Parmela and high-order Transport for bunch charges from 50 pC to 1 nC. Beyond the diagnostics, this system uses the emittance compensating solenoids and a low energy, high resolution spectrometer (LES) to help tune for best operating point and match to the linac. Optical symmetries in the design of the 25.5° extraction line provide 1:1 phase space transfer without linear dispersion or use of sextu...

  13. Beam Dynamics Studies for a Laser Acceleration Experiment

    The NLC Test Accelerator (NLCTA) at SLAC was built to address various beam dynamics issues for the Next Linear Collider. An S-Band RF gun is being installed together with a large-angle extraction line at 60 MeV followed by a matching section, buncher and final focus for the laser acceleration experiment, E163. The laser-electron interaction area is followed by a broad range, high resolution spectrometer (HES) for electron bunch analysis. Another spectrometer at 6 MeV will be used for analysis of bunch charges up to 1 nC. Emittance compensating solenoids and the low energy spectrometer (LES) will be used to tune for best operating point and match to the linac. Optical symmetries in the design of the 25.5o extraction line provide 1:1 phase space transfer without use of sextupoles for a large, 6D phase space volume and range of input conditions. Design techniques, tolerances, tuning sensitivities and orthogonal knobs are discussed

  14. Curcumin Mitigates Accelerated Aging after Irradiation in Drosophila by Reducing Oxidative Stress

    Ki Moon Seong; Mira Yu; Kyu-Sun Lee; Sunhoo Park; Young Woo Jin; Kyung-Jin Min

    2015-01-01

    Curcumin, belonging to a class of natural phenol compounds, has been extensively studied due to its antioxidative, anticancer, anti-inflammatory, and antineurodegenerative effects. Recently, it has been shown to exert dual activities after irradiation, radioprotection, and radiosensitization. Here, we investigated the protective effect of curcumin against radiation damage using D. melanogaster. Pretreatment with curcumin (100 μM) recovered the shortened lifespan caused by irradiation and incr...

  15. Accelerated Stress Testing of Hydrocarbon-Based Encapsulants for Medium-Concentration CPV Applications

    Kempe, M. D.; Moricone, T. J.; Kilkenny, M.; Zhang, J. Z.

    2011-02-01

    Concentrating photovoltaic (CPV) systems have great potential to reduce photovoltaic (PV) electricity costs because of the relatively low cost of optical components as compared to PV cells. A transparent polymeric material is used to optically couple the PV cell to optical components and is thus exposed to the concentrated light source at elevated temperatures. In this work polymeric encapsulant materials are positioned close to a Xenon arc lamp to expose them to ultraviolet radiation (UV) that is about 42 times as intense as sunlight. Furthermore, different glass types are used as filters to modify the spectral distribution of light in the UV range. A strong sensitivity of non-silicone-based encapsulants to light below ~350 nm is demonstrated. Of all the materials examined in this study, the polydimethyl silicone samples performed the best. The next best material was an ionomer which maintained optical transmission but became photo-oxidized where exposed to the atmosphere.

  16. A study of learning stress and stress management strategies of the students of postgraduate level: a case study of Islamia University of Bahawalpur, Pakistan

    BUKHSH, Qadir; Shahzad, Abid Hussain; Nisa, Muzammil

    2011-01-01

    Stress management .........................This study was designed to study Learning Stress and Stress Management Strategies for University Students. The objectives of the study were to find out the common symptoms of stress, causes of stress and to suggest stress management strategies used by students for coping with stress. For collecting data, survey method was adopted. This study was completed by following the procedure of descriptive method of research. 39 questions were used for data co...

  17. A study on phase stress of centrifugally cast duplex stainless steel by neutron diffraction

    With great corrosion resistance and mechanical property, ferrite-austenitic duplex stainless steel have been applied to components in corrosive environments such as sea water pumps. Due to different coefficients of thermal expansion and elastic modulus between the two phases, phase stress occurs after heat treatment or material processing such as casting, forging and machining, which may affect material properties such as fatigue strength, welding stability and so on. In this study, phase stress distribution along thickness direction of duplex stainless steel hollow cylinders fabricated by centrifugal casting was measured by pulsed neutron diffraction using time-of-flight (TOF) method. Also lattice strain and phase stress evolution were discussed by in-situ neutron diffraction measurement during tensile test. All these measurements were conducted at Japan Proton Accelerator Research Complex (J-PARC). (author)

  18. System and safety studies of accelerator driven transmutation systems

    The research on safety of Accelerator-Driven Transmutation Systems (ADS) at the department has been focused on: a) ADS core design and development of advanced nuclear fuel optimised for high transmutation rates and good safety features; b) analysis of ADS-dynamics c) computer code and nuclear data development relevant for simulation and optimization of ADS; d) participation in ADS experiments including 1 MW spallation target manufacturing, subcritical experiments MUSE (CEA-Cadarache). Moreover, during the reporting period the EU-project 'IABAT', co-ordinated by the department has been finished and 4 other projects have been initiated in the frame of the 5th European Framework Programme. Most of the research topics reported in this paper are referred to appendices, which have been published in the open literature. The topics, which are not yet published, are described here in more details

  19. Supernova Acceleration Probe: Studying Dark Energy with Type Ia Supernovae

    Albert, J; Allam, S; Althouse, W E; Amanullah, R; Annis, J; Astier, Pierre; Aumeunier, M; Bailey, S; Baltay, C; Barrelet, E; Basa, S; Bebek, C; Bergström, L; Bernstein, G; Bester, M; Besuner, B; Bigelow, B; Blandford, R; Bohlin, R; Bonissent, A; Bower, C; Brown, M; Campbell, M; Carithers, W; Cole, D; Commins, Eugene D; Craig, W; Davis, T; Dawson, K; Day, C; De Harveng, M; De Jongh, F; Deustua, S; Diehl, H; Dobson, T; Dodelson, S; Ealet, A; Ellis, R; Emmet, W; Figer, D; Fouchez, D; Frerking, M; Frieman, J A; Fruchter, A; Gerdes, D; Gladney, L; Goldhaber, G; Goobar, A; Groom, D; Heetderks, H; Hoff, M; Holland, S; Huffer, M; Hui, L; Huterer, D; Jain, B; Jelinsky, P; Juramy, C; Karcher, A; Kent, S; Kahn, S; Kim, A; Kolbe, W; Krieger, B; Kushner, G; Kuznetsova, N; Lafever, R; Lamoureux, J; Lampton, M; Lefèvre, O; Lebrun, V; Levi, M; Limon, P; Lin, H; Linder, E; Loken, S; Lorenzon, W; Malina, R; Marian, L; Marriner, J P; Marshall, P; Massey, R; Mazure, A; McGinnis, B; McKay, T; McKee, S; Miquel, R; Mobasher, B; Morgan, N; Mortsell, E; Mostek, N; Mufson, S; Musser, J; Nakajima, R; Nugent, P; Olus, H; Pain, R; Palaio, N; Pankow, D; Peoples, John; Perlmutter, S; Peterson, D; Prieto, E; Rabinowitz, D; Réfrégier, A; Rhodes, J; Roe, N; Rusin, D; Scarpine, V; Schubnell, M; Seiffert, M; Sholl, M; Shukla, H; Smadja, G; Smith, R M; Smoot, George F; Snyder, J; Spadafora, A; Stabenau, F; Stebbins, A; Stoughton, C; Szymkowiak, A; Tarle, G; Taylor, K; Tilquin, A; Tomasch, A; Tucker, D; Vincent, D; Von der Lippe, H; Walder, J P; Wang, G; Weinstein, A; Wester, W; White, M

    2005-01-01

    The Supernova Acceleration Probe (SNAP) will use Type Ia supernovae (SNe Ia) as distance indicators to measure the effect of dark energy on the expansion history of the Universe. (SNAP's weak-lensing program is described in a companion White Paper.) The experiment exploits supernova distance measurements up to their fundamental systematic limit; strict requirements on the monitoring of each supernova's properties lead to the need for a space-based mission. Results from pre-SNAP experiments, which characterize fundamental SN Ia properties, will be used to optimize the SNAP observing strategy to yield data, which minimize both systematic and statistical uncertainties. SNAP has achieved technological readiness and the collaboration is poised to begin construction.

  20. Accelerating Wave Function Convergence in Interactive Quantum Chemical Reactivity Studies

    Mühlbach, Adrian H; Reiher, Markus

    2015-01-01

    The inherently high computational cost of iterative self-consistent-field (SCF) methods proves to be a critical issue delaying visual and haptic feedback in real-time quantum chemistry. In this work, we introduce two schemes for SCF acceleration. They provide a guess for the initial density matrix of the SCF procedure generated by extrapolation techniques. SCF optimizations then converge in fewer iterations, which decreases the execution time of the SCF optimization procedure. To benchmark the proposed propagation schemes, we developed a test bed for performing quantum chemical calculations on sequences of molecular structures mimicking real-time quantum chemical explorations. Explorations of a set of six model reactions employing the semi-empirical methods PM6 and DFTB3 in this testing environment showed that the proposed propagation schemes achieved speedups of up to thirty percent as a consequence of a reduced number of SCF iterations.

  1. Electromagnetic simulation study of dielectric wall accelerator structures

    ZHAO Quan-Tang; ZHANG Zi-Min; YUAN Ping; CAO Shu-Chun; SHEN Xiao-Kang; JING Yi; LIU Ming; ZHAO Hong-Wei

    2012-01-01

    Two types of dielectric wall accelerator (DWA) structures,a bi-polar Blumlein line and zero integral pulse line (ZIP) structures were investigated.The high gradient insulator simulated by the particle in cell code confirms that it has little influence on the axial electric field.The results of simulations using CST microwave studio indicate how the axial electric field is formed,and the electric field waveforms agree with the theoretical one very well.The influence of layer-to-layer coupling in a ZIP structure is much smaller and the electric field waveform is much better.The axial of the Blumlein structure's electric field has better axial stability.From both of the above,it found that for a shorter pulse width,the axial electric field is much higher and the pulse stability and fidelity are much better.The CST simulation is very helpful for designing DWA structures.

  2. Accelerating Wave Function Convergence in Interactive Quantum Chemical Reactivity Studies.

    Mühlbach, Adrian H; Vaucher, Alain C; Reiher, Markus

    2016-03-01

    The inherently high computational cost of iterative self-consistent field (SCF) methods proves to be a critical issue delaying visual and haptic feedback in real-time quantum chemistry. In this work, we introduce two schemes for SCF acceleration. They provide a guess for the initial density matrix of the SCF procedure generated by extrapolation techniques. SCF optimizations then converge in fewer iterations, which decreases the execution time of the SCF optimization procedure. To benchmark the proposed propagation schemes, we developed a test bed for performing quantum chemical calculations on sequences of molecular structures mimicking real-time quantum chemical explorations. Explorations of a set of six model reactions employing the semi-empirical methods PM6 and DFTB3 in this testing environment showed that the proposed propagation schemes achieved speedups of up to 30% as a consequence of a reduced number of SCF iterations. PMID:26788887

  3. System and safety studies of accelerator driven transmutation systems

    Gudowski, W.; Wallenius, J.; Tucek, K.; Eriksson, Marcus; Carlsson, Johan; Seltborg, P.; Cetnar, J. [Royal Inst. of Technology, Stockholm (Sweden). Dept. of Nuclear and Reactor Physics

    2001-05-01

    The research on safety of Accelerator-Driven Transmutation Systems (ADS) at the department has been focused on: a) ADS core design and development of advanced nuclear fuel optimised for high transmutation rates and good safety features; b) analysis of ADS-dynamics c) computer code and nuclear data development relevant for simulation and optimization of ADS; d) participation in ADS experiments including 1 MW spallation target manufacturing, subcritical experiments MUSE (CEA-Cadarache). Moreover, during the reporting period the EU-project 'IABAT', co-ordinated by the department has been finished and 4 other projects have been initiated in the frame of the 5th European Framework Programme. Most of the research topics reported in this paper are referred to appendices, which have been published in the open literature. The topics, which are not yet published, are described here in more details.

  4. Studies of pear-shaped nuclei using accelerated radioactive beams

    Gaffney, L P; Scheck, M; Hayes, A B; Wenander, F; Albers, M; Bastin, B; Bauer, C; Blazhev, A; Bonig, S; Bree, N; Cederkall, J; Chupp, T; Cline, D; Cocolios, T E; Davinson, T; DeWitte, H; Diriken, J; Grahn, T; Herzan, A; Huyse, M; Jenkins, D G; Joss, D T; Kesteloot, N; Konki, J; Kowalczyk, M; Kroll, Th; Kwan, E; Lutter, R; Moschner, K; Napiorkowski, P; Pakarinen, J; Pfeiffer, M; Radeck, D; Reiter, P; Reynders, K; Rigby, S V; Robledo, L M; Rudigier, M; Sambi, S; Seidlitz, M; Siebeck, B; Stora, T; Thoele, P; Van Duppen, P; Vermeulen, M J; von Schmid, M; Voulot, D; Warr, N; Wimmer, K; Wrzosek-Lipska, K; Wu, C Y; Zielinska, M

    2013-01-01

    There is strong circumstantial evidence that certain heavy, unstable atomic nuclei are ‘octupole deformed’, that is, distorted into a pear shape. This contrasts with the more prevalent rugby-ball shape of nuclei with reflection-symmetric, quadrupole deformations. The elusive octupole deformed nuclei are of importance for nuclear structure theory, and also in searches for physics beyond the standard model; any measurable electric-dipole moment (a signature of the latter) is expected to be amplified in such nuclei. Here we determine electric octupole transition strengths (a direct measure of octupole correlations) for short-lived isotopes of radon and radium. Coulomb excitation experiments were performed using accelerated beams of heavy, radioactive ions. Our data on and $^{224}$Ra show clear evidence for stronger octupole deformation in the latter. The results enable discrimination between differing theoretical approaches to octupole correlations, and help to constrain suitable candidates for experimental...

  5. Particle acceleration studies with intense lasers and advanced light sources

    Murphy, C. D.; Gray, R. J.; MacLellan, D. A.; Rusby, D.; McKenna, P.; Ridgers, C. P.; Booth, N.; Robinson, A. P. L.; Wilson, L.; Green, J. S.

    2013-10-01

    The interaction of lasers with matter is a subject which has progressed rapidly over the last two decades as higher intensity lasers are found to have possible applications in inertial fusion, laboratory astrophysics and ion acceleration for oncology or ultrafast proton probing. All of these applications require a good understanding of laser-electron coupling and fast electron transport in solid targets which has proven difficult to diagnose. Here we present data from an experiment carried out on the Astra Gemini laser system at STFC-Rutherford Appleton Laboratory, where novel targets and diagnostics illuminate the complex processes at play. An outline of how x-ray free electron lasers may further expand our understanding of such processes will also be described.

  6. Studies on mechanisms of the laser particle acceleration; Untersuchungen zu Mechanismen der Laser-Teilchenbeschleunigung

    Aurand, Bastian

    2012-06-20

    Within the last decade, many developments towards higher energies and particle numbers paved the way of particle acceleration performed by high intensity laser systems. Up to now, the process of a field-induced acceleration process (Target-Normal-Sheath-Acceleration (TNSA)) is investigated the most. Acceleration occurs as a consequence of separation of charges on a surface potential. Here, the broad energy spectrum is a problem not yet overcome although many improvements were achieved. Calculations for intensities higher than 10{sup 20..21} W/cm{sup 2} give hint that Radiation-Pressure-Acceleration (RPA) may lead to a sharper, monoenergetic energy spectrum. Within the framework of this thesis, the investigation of the acceleration mechanism is studied experimentally in the intensity range of 10{sup 19} W/cm{sup 2}. Suitable targets were developed and applied for patent. A broad range of parameters was scanned by means of high repetition rates together with an adequate laser system to provide high statistics of several thousands of shots, and the dependence of target material, intensity, laser polarisation and pre plasma-conditions was verified. Comparisons with 2-d numeric simulations lead to a model of the acceleration process which was analyzed by several diagnostic methods, giving clear evidence for a new, not field-induced acceleration process. In addition, a system for a continuous variation of the polarization based on reflective optics was developed in order to overcome the disadvantages of retardation plates, and their practicability of high laser energies can be achieved.

  7. Analytical and Experimental Study of Residual Stresses in CFRP

    Chia-Chin Chiang

    2013-01-01

    Full Text Available Fiber Bragg Grating sensors (FBGs have been utilized in various engineering and photoelectric fields because of their good environment tolerance. In this research, residual stresses of carbon fiber reinforced polymer composites (CFRP were studied using both experimental and analytical approach. The FBGs were embedded inside middle layers of CFRP to study the formation of residual stress during curing process. Finite element analysis was performed using ABAQUS software to simulate the CFRP curing process. Both experimental and simulation results showed that the residual stress appeared during cooling process and the residual stresses could be released when the CFRP was machined to a different shape.

  8. Kinetic studies of stress-corrosion cracking

    Noronha, P. J.

    1977-01-01

    Use of time-to-failure curves for stress-corrosion cracking processes may lead to incorrect estimates of structural life, if material is strongly dependent upon prestress levels. Technique characterizes kinetics of crackgrowth rates and intermediate arrest times by load-level changes.

  9. A Factor Analytic Study of the Teaching Events Stress Inventory.

    Alexander, Livingston; And Others

    The purpose of this study was to determine if definitive factors emerge from the responses of teachers to the Teaching Events Stress Inventory (TESI). In a series of three studies during the years 1980 to 1982, data were collected to assess the levels and sources of stress experienced by 660 teachers in central and western Kentucky. The subjects…

  10. Proteomic studies of drought stress response in Fabaceae

    Tanja ZADRAŽNIK

    2015-11-01

    Full Text Available Drought stress is a serious threat to crop production that influences plant growth and development and subsequently causes reduced quantity and quality of the yield. Plant stress induces changes in cell metabolism, which includes differential expression of proteins. Proteomics offer a powerful approach to analyse proteins involved in drought stress response of plants. Analyses of changes in protein abundance of legumes under drought stress are very important, as legumes play an important role in human and animal diet and are often exposed to drought. The presented results of proteomic studies of selected legumes enable better understanding of molecular mechanisms of drought stress response. The study of drought stress response of plants with proteomic approach may contribute to the development of potential drought-response markers and to the development of drought-tolerant cultivars of different legume crop species.

  11. Stress of Kindergarten teachers: How we tried to detect and to reduce it by using a small and wearable ECG and acceleration measuring device?

    Shirouzu, Shigenori; Seno, Yumeka; Tobioka, Ken; Masaki, Takeo; Yasumatsu, Kiyotaka; Mishima, Norio; Sugano, Hisanobu

    2015-08-01

    In 2014 school year, four female teachers of Nazareth Kindergarten decided to resign (DRT) due to workplace stress caused by human relationships between themselves. Our preliminary interview investigation revealed there was a stressor (STR), a certain elder female teacher and her less polite words and attitude. Using small and wearable ECG and acceleration measuring device, we measured 24 hour's autonomic nervous system's activity (ASNA) and sleep behavior of the STR and surrounding teachers, and tried to evaluate their stress objectively and to understand the reason of STR's less polite behaviors. For comparison, we also measured female Mind-Body Medicine (MBM) patients suffering adjustment disorder and clinical depression. PMID:26737766

  12. Accelerated Resolution Therapy for treatment of pain secondary to symptoms of combat-related posttraumatic stress disorder

    Kevin E. Kip

    2014-05-01

    Full Text Available Background: As many as 70% of veterans with chronic pain treated within the US Veterans Administration (VA system may have posttraumatic stress disorder (PTSD, and conversely, up to 80% of those with PTSD may have pain. We describe pain experienced by US service members and veterans with symptoms of PTSD, and report on the effect of Accelerated Resolution Therapy (ART, a new, brief exposure-based therapy, on acute pain reduction secondary to treatment of symptoms of PTSD. Methods: A randomized controlled trial of ART versus an attention control (AC regimen was conducted among 45 US service members/veterans with symptoms of combat-related PTSD. Participants received a mean of 3.7 sessions of ART. Results: Mean age was 41.0 + 12.4 years and 20% were female. Most veterans (93% reported pain. The majority (78% used descriptive terms indicative of neuropathic pain, with 29% reporting symptoms of a concussion or feeling dazed. Mean pre-/post-change on the Pain Outcomes Questionnaire (POQ was −16.9±16.6 in the ART group versus −0.7±14.2 in the AC group (p=0.0006. Among POQ subscales, treatment effects with ART were reported for pain intensity (effect size = 1.81, p=0.006, pain-related impairment in mobility (effect size = 0.69, p=0.01, and negative affect (effect size = 1.01, p=0.001. Conclusions: Veterans with symptoms of combat-related PTSD have a high prevalence of significant pain, including neuropathic pain. Brief treatment of symptoms of combat-related PTSD among veterans by use of ART appears to acutely reduce concomitant pain.

  13. Particle selection for laser-accelerated proton therapy feasibility study

    In this paper we present calculations for the design of a particle selection system for laser-accelerated proton therapy. Laser-accelerated protons coming from a thin high-density foil have broad energy and angular spectra leading to dose distributions that cannot be directly used for therapeutic applications. Our solution to this problem is a compact particle selection and collimation device that delivers small pencil beams of protons with desired energy spectra. We propose a spectrometer-like particle selection and beam modulation system in which the magnetic field will be used to spread the protons spatially according to their energies and emitting angles. Subsequently, an aperture will be used to select the protons within a therapeutic window of energy (energy modulation). It will be shown that for the effective proton spatial differentiation, the primary collimation device should be used, which will collimate protons to the desired angular distribution and limit the spatial mixing of different energy protons once they have traveled through the magnetic system. Due to the angular proton distribution, the spatial mixing of protons of different energies will always be present and it will result in a proton energy spread with the width depending on the energy. For 250 MeV protons, the width (from the maximum to the minimum energy) is found to be 50 MeV for the magnetic field configuration used in our calculations. As the proton energy decreases, its energy width decreases as well, and for 80 MeV protons it equals 9 MeV. The presence of the energy width in the proton energy distribution will modify the depth dose curves needed for the energy modulation calculation. The matching magnetic field setup will ensure the refocusing of the selected protons and the final beam will be collimated by the secondary collimator. The calculations presented in this article show that the dose rate that the selection system can yield is on the order of D=260 Gy/min for a field size

  14. Laser-plasma-accelerators-A novel, versatile tool for space radiation studies

    The potential of laser-plasma-based accelerator technology for future advanced space radiation studies is investigated. Laser-plasma accelerators have been shown to be capable of robust generation of particle beams such as electrons, protons, neutrons and ions, as well as photons, having a wide range of accessible parameters. Further, instead of maximum accelerating fields of the order of MV/m as in state-of-the-art accelerators, laser-plasma acceleration operates with fields up to TV/m and can thus be used to reach as yet inaccessible parameter regimes, but which are very relevant to space radiation studies. Due to their versatility and compactness, the same laser-plasma-accelerator can be used in university-scale labs to generate different kinds of particle and photon beams, each yielding up to kGy doses per shot, and allowing combinations of different kinds of radiation production simultaneously. Laser-plasma-accelerators provide the advantage of cost-effective radiation generation, thus ameliorating the current shortage of beam time for testing of radiation resistivity of electronic components. Beyond this, laser-plasma-accelerators can be used to reproduce certain aspects of space radiation, e.g. broad, decreasing multi-MeV-scale spectra, with substantially improved level of fidelity, as compared to state-of-the-art technology. This can increase the significance of electronic components testing, and in turn yield increased reliability and safety of future manned or unmanned space missions, high-altitude flights, as well as the electronic components used in harsh radiation environments in general. Laser-plasma-accelerators may therefore become indispensable tools for next-generation space radiation studies.

  15. Psychological Stress on Female Mice Diminishes the Developmental Potential of Oocytes: A Study Using the Predatory Stress Model

    Yu-Xiang Liu; Ya-Nan Cheng; Yi-Long Miao; De-Li Wei; Li-Hua Zhao; Ming-Jiu Luo; Jing-He Tan

    2012-01-01

    Although the predatory stress experimental protocol is considered more psychological than the restraint protocol, it has rarely been used to study the effect of psychological stress on reproduction. Few studies exist on the direct effect of psychological stress to a female on developmental competence of her oocytes, and the direct effect of predatory maternal stress on oocytes has not been reported. In this study, a predatory stress system was first established for mice with cats as predators...

  16. Hyperion Studies Of Crop Stress In Mexico

    Lobell, David B.; Asner, Gregory P.

    2004-01-01

    Satellite-based measurements of crop stress could provide much needed information for cropland management, especially in developing countries where other precision agriculture technologies are too expensive (Pierce and Nowak 1999; Robert 2002). For example, detection of areas that are nitrogen deficient or water stressed could guide fertilizer and water management decisions for all farmers within the swath of the satellite. Several approaches have been proposed to quantify canopy nutrient or water content based on spectral reflectance, most of which involve combinations of reflectance in the form of vegetation indices. While these indices are designed to maximize sensitivity to leaf chemistry, variations in other aspects of plant canopies may significantly impact remotely sensed reflectance. These confounding factors include variations in canopy structural properties (e.g., leaf area index, leaf angle distribution) as well as the extent of canopy cover, which determines the amount of exposed bare soil within a single pixel. In order to assess the utility of spectral indices for monitoring crop stress, it is therefore not only necessary to establish relationships at the leaf level, but also to test the relative importance of variations in other canopy attributes at the spatial scale of the remote sensing measurement. In this context, the relative importance of a given attribute will depend on (1) the sensitivity of the reflectance index to variation in the attribute and (2) the degree to which the attribute varies spatially and temporally.

  17. Spectrographic Approach to Study of RF Conditioning Process in Accelerating RF Structures

    Tomizawa, H; Taniuchi, T

    2004-01-01

    The acceleration gradient of a linac is limited by rf breakdown in its accelerating structure. We applied an imaging spectrograph system to study the mechanism of rf breakdown phenomena in accelerating rf structures. Excited outgases emit light during rf breakdown, and the type of outgases depend on surface treatments and rinsing methods for their materials. To study rf breakdown, we used 2-m-long accelerating structures and investigated the effects when high-pressure ultrapure water rinsing (HPR) treatment was applied to these rf structures. We performed experiments to study the outgases under rf conditioning with quadruple mass spectroscopy and imaging spectrography. As a result, we could observe instantly increasing signals at mass numbers of 2 (H2

  18. A visualization study of Rayleigh-Taylor instability of flames generated by sudden acceleration

    Ma, L.; Yao, X.; Chomiak, J. [Chalmers Univ. of Technology, Goeteborg (Sweden). Dept. of Thermo- and Fluid Dynamics

    1996-07-01

    The Rayleigh-Taylor instability phenomenon occurs in flames when the pressure in the products is higher than in the mixture. The development of this phenomenon in premixed flames was investigated experimentally. A square glass tube for standard flammability limit studies and a methane air mixture were used in the experiment. The flame was accelerated by a falling piston and flame shapes and positions were recorded. Results showed that sudden acceleration does not induce small scale instabilities of flame, contrary to predictions of existing linear theories. The accelerated flames form large scale bubbles which propagate with constant speed relative to the gas. 20 refs., 6 figs.

  19. Mechanical Design of Superconducting Accelerator Magnets

    Toral, Fernando

    2015-01-01

    This paper is about the mechanical design of superconducting accelerator magnets. First, we give a brief review of the basic concepts and terms. In the following sections, we describe the particularities of the mechanical design of different types of superconducting accelerator magnets: solenoids, cos-theta, superferric, and toroids. Special attention is given to the pre-stress principle, which aims to avoid the appearance of tensile stresses in the superconducting coils. A case study on a co...

  20. Applications of accelerator mass spectrometry to environmental and paleoclimate studies

    Full text: A wide range of climatic, geologic and archaeological records can be characterized by measuring their 14C and 10Be concentrations, using the accelerator mass spectrometry (AMS). These records are found not only in the traditional sampling sites such as lake sediments and ice cores, but also in diverse natural records such as: loess/paleosol deposits, corals, speleothems and forest-fire horizons. The in-situ production of cosmogenic radionuclides in terrestrial materials is a new methodology which provides several possibilities of determining their chronology. The purpose of this paper is to highlight selected applications of AMS, which have bearing to our understanding of both chronology of archival materials, and learning about climatic changes in the past. The development of a good chronology is very important to the understanding of past climatic changes and their relationship to other events. To correlate distinct climatic features requires that we are able to correlate phenomena, which can be dated independently. The improvement in the radiocarbon calibration curve over the last 26,000 yr has allowed us to cross-correlate fluctuations in the 14C curve directly with those in the ice-core record. This capability has improved attempts to cross-correlate different climatic events observed in one record with other proxy records. This extension of the calibration curve used tree rings to about 11,500 calibrated years and beyond that used corals and varved marine sediments. Other newer but perhaps less-reliable records can take us back to the limits of radiocarbon dating, using lake sediments and speleothem records. An important consideration in the geochronology of past climate change is that the same event might be manifest in different ways in different parts of the world. For example, the uniformly cold younger Dryas in northern Europe and eastern North America might not have the same expression elsewhere. To give one example, although the Younger

  1. Psychological stress during pregnancy and stillbirth: prospective study

    Wisborg, K.; Barklin, A.; Hedegaard, M.;

    2008-01-01

    OBJECTIVE: To study the association between psychological stress during pregnancy and stillbirth. DESIGN: Prospective follow-up study. SETTING: Aarhus University Hospital, Skejby, Denmark,1989-98. POPULATION: A total of 19 282 singleton pregnancies in women with valid information about psychologi......OBJECTIVE: To study the association between psychological stress during pregnancy and stillbirth. DESIGN: Prospective follow-up study. SETTING: Aarhus University Hospital, Skejby, Denmark,1989-98. POPULATION: A total of 19 282 singleton pregnancies in women with valid information about...... psychological stress during pregnancy. METHODS: Information about psychological stress during pregnancy was obtained from questionnaires and measured by the 12-item General Health Questionnaires (GHQ). A score was generated by the sum of all the answers, each contributing a value between 0 (low psychological...... stress) and 3 (high psychological stress). Women with an intermediate level of psychological stress (scores of 7-11) were considered the reference group. Scores of 0-6 were defined as a low level of psychological stress and scores of 12-36 as the highest level. The association between psychological...

  2. Decreasing Students' Stress through Time Management Training: An Intervention Study

    Häfner, Alexander; Stock, Armin; Oberst, Verena

    2015-01-01

    The aim of this study was to examine the effects of a time management training program on perceived control of time and perceived stress in the context of higher education. Twenty-three undergraduate students attended a time management training intervention and reported demands, perceived stress and perceived control of time directly before 2 and…

  3. Dynamic triggering: Stress modeling and a case study

    Gonzalez-Huizar, Hector; Velasco, Aaron A.

    2011-02-01

    Changes in the static stress can trigger nearby earthquakes that occur within a few fault lengths from the causative event. Transient stresses caused by passage of surface waves commonly trigger events at remote distances, yet little is documented or understood about the processes and stresses necessary for remote triggering. To understand the causative stresses and environments behind remote, or dynamic, triggering, we must decipher the stresses caused by the passage of the surface waves in relation to the local stress field and fault conditions where the triggered events occur. In this study, we model the change in the stress field that the passing of Rayleigh and Love waves causes on a fault plane of arbitrary orientation relative to the direction of propagation of the waves, and we apply a Coulomb failure criterion to calculate the potential of these stress changes to trigger reverse, normal, or strike-slip failure. We compare these model results with data from dynamically triggered earthquakes in the Australian Bowen Basin, an area with low seismicity and mapped regional stress and that is at the margin of a stable continental craton. Our data analysis shows that for this region, surface waves arriving at 45° from the average strike direction are the most likely to trigger local seismicity. This agrees with our observations.

  4. FLUKA Monte Carlo for Basic Dosimetric Studies of Dual Energy Medical Linear Accelerator

    K. Abdul Haneefa; T. Siji Cyriac; M. M. Musthafa; Ganapathi Raman, R.; Hridya, V. T.; A Siddhartha; Shakir, K. K.

    2014-01-01

    General purpose Monte Carlo code for simulation of particle transport is used to study the basic dosimetric parameters like percentage depth dose and dose profiles and compared with the experimental measurements from commercial dual energy medical linear accelerator. Varian Clinac iX medical linear accelerator with dual energy photon beams (6 and 15 MV) is simulated using FLUKA. FLAIR is used to visualize and edit the geometry. Experimental measurements are taken for 100 cm source-to-surface ...

  5. Understanding Abiotic Stress Tolerance Mechanisms: Recent Studies on Stress Response in Rice

    Ji-Ping Gao; Dai-Yin Chao; Hong-Xuan Lin

    2007-01-01

    Abiotic stress is the main factor negatively affecting crop growth and productivity worldwide. The advances in physiology, genetics, and molecular biology have greatly improved our understanding of plant responses to stresses. Rice plants are sensitive to various abiotic stresses. In this short review, we present recent progresses in adaptation of rice to salinity, water deficit and submergence. Many studies show that salt tolerance is tightly associated with the ability to maintain ion homeostasis under salinity. Na+ transporter SKC1 unloads NaMrom xylem, plasma membrane NaVHTantiporter SOS1 excludes sodium out of cytosol and tonoplast Na+/H+antiporter NHX1 sequesters Na+ into the vacuole. Silicon deposition in exodermis and endodermis of rice root reduces sodium transport through the apoplastic pathway. A number of transcription factors regulate stress-inducible gene expression that leads to initiating stress responses and establishing plant stress tolerance. Overexpression of some transcription factors, including DREB/CBF and MAC, enhances salt, drought, and cold tolerance in rice. A variant of one of ERF family genes, Sub1A-1, confers immersion tolerance to lowland rice. These findings and their exploitation will hold promise for engineering breeding to protect crop plants from certain abiotic stresses.

  6. Dextran's effects on stressed lenses: water, electrolyte, and radioisotope studies

    To evaluate the beneficial effects of dextran 40 as an additive to infusion solutions, we studied an experimental model of lens stress with use of buffered, low calcium (Ca++)-containing solutions. Incubation in low Ca++ solutions (pCa = 10.7) for ten hours (stress period) resulted in lens swelling and electrolyte imbalances that were irreversible even with reincubation in physiologic, normal Ca++-containing media (pCa = 2.7) (recovery period). The addition of 6% or more of dextran to the media inhibited lens water gain during the stress period. It also rendered the resultant electrolyte imbalances reversible during the recovery period, thus exerting a protective effect. Radioisotope-tracer studies showed that dextran improved the ability of the lens to accumulate rubidium chloride Rb 86 and reduced its efflux during both the stress and recovery periods. Dextran did not markedly decrease sodium chloride Na 22 uptake by lenses under stress

  7. Residual stress studies of austenitic and ferritic steels

    Residual studies have been made on austenitic and ferritic steels of the types used as structural materials. The residual stress results presented here will include residual stress measurements in the heat-affected zone on butt welded Type 304 stainless steel pipes, and the stresses induced in Type 304 austenitic stainless steel and Type A508 ferritic steel by several surface preparations. Such surface preparation procedures as machining and grinding can induce large directionality effects in the residual stresses determined by X-ray techniques and some typical data will be presented. A brief description is given of the mobile X-ray residual stress apparatus used to obtain most of the data in these studies. (author)

  8. Residual Stress Studies Using the Cairo Fourier Diffractometer Facility

    The present paper deals with residual stress studies using the Cairo Fourier diffractometer facility CFDF. The CFDF is a reverse - time of -flight (RTOF) diffractometer; applies a Fourier chopper. The measurements were performed for copper samples in order to study the residual stress after welding. The maximum modulation of the Fourier chopper during the measurements was 136 khz; leading to a time resolution half-width of about 7 μ s. It has been found from the present measurements that, the resulting diffraction spectra could be successfully used for studying the residual stress; in the wavelength range between 0.7-2.9 A degree at ∼ 0.45 % relative resolution

  9. Impacts of a GHG-induced climate change on crop yields: effects of acceleration in maturation, moisture stress and optimal temperature

    The present study involves using the Canadian Climate Centre (CCC) climate change scenario to evaluate the impacts of a CO2-induced climate change on agriculture in Quebec and vicinity. Climate change using the CCC General Circulating Model (GCM) data are fed into a crop model (FAO) so as to gauge the changes in agroclimatic factors such as growing season length and growing degree days, and subsequently potential yield changes for a variety of cereal (C3 and C4), leguminous, oleaginous, vegetable and special crops, for twelve major agricultural regions in southern Quebec. Our results show that depending upon the agricultural zone and crop type, yields may increase (ex. corn and sorghum by 20%) or decrease (ex. wheat and soybean by 20 to 30%). Also, these crop yield changes appear to be related to acceleration in maturation rates, mainly to change in moisture stress and to shifts in optimal thermal growth conditions. These possible shifts in agricultural production potentials would solicit the formulation of appropriate adaptation strategies. 77 refs., 6 figs., 5 tabs

  10. Theoretical and numerical studies on the transport of transverse beam quality in plasma-based accelerators

    This work examines effects, which impact the transverse quality of electron-beams in plasma-based accelerators, by means of theoretical and numerical methods. Plasma-based acceleration is a promising candidate for future particle accelerator technologies. In plasma-based acceleration, highly intense laser beams or high-current relativistic particle beams are focused into a plasma to excite plasma-waves with extreme transverse and longitudinal electric fields. The amplitude of these fields exceed with 10-100 GV/m the ones in today's radio-frequency accelerators by several orders of magnitude, hence, in principle allowing for accordingly shorter and cheaper accelerators based on plasma. Despite the tremendous progress in the recent decade, beams from plasma accelerators are not yet achieving the quality as demanded for pivotal applications of relativistic electron-beams, e.g. free-electron lasers (FELs).Studies within this work examine how the quality can be optimized in the production of the beams and preserved during the acceleration and transport to the interaction region. Such studies cannot be approached purely analytical but necessitate numerical methods, such as the Particle-In-Cell (PIC) method, which can model kinetic, electrodynamic and relativistic plasma phenomena. However, this method is computationally too expensive for parameter-scans in three-dimensional geometries. Hence, a quasi-static PIC code was developed in connection with this work, which is significantly more effective than the full PIC method for a class of problems in plasma-based acceleration.The evolution of the emittance of beams which are injected into plasma modules was studied in this work by means of theoretical and the above numerical methods. It was shown that the beam parameters need to be matched accurately into the focusing plasma-channel in order to allow for beam-quality preservation. This suggested that new extraction and injection-techniques are required in staged plasma-acceleration

  11. Study of fatigue durability of advanced composite materials under conditions of accelerated loading

    Shih, H. M.

    1979-01-01

    The effect of temperature on the tension-tension fatigue life of the T300/5208 graphite/epoxy angle-ply laminate system was investigated in an effort to develop an acceptable and reliable method of accelerated loading. Typical S log sub 10 N curves were determined experimentally at 25 C, 75 C, and 115 C. The time-temperature superposition principle was employed to find the shift factors of uniaxial fatigue strength, and a general linear equation of S log sub 10 N for shifting purpose was established. The combined techniques of cyclic creep measurements and optical microscopy upon fatigue failure allow some assessment of the possible physical basis of S log 10 N curve shifting. Before fatigue, the laminates at all test temperatures and stress levels undergo a unique damage mechanism during fatigue loading. It is concluded that an accelerated loading method is feasible.

  12. Efficiency of particle acceleration at interplanetary shocks: Statistical study of STEREO observations

    Dresing, Nina; Klassen, Andreas; Heber, Bernd

    2016-01-01

    Context. Among others, shocks are known to be accelerators of energetic charged particles. However, many questions regarding the acceleration efficiency and the required conditions are not fully understood. In particular, the acceleration of electrons by shocks is often questioned. Aims. In this study we determine the efficiency of interplanetary shocks for $<$100 keV electrons, and for ions at $\\sim$0.1 and $\\sim$2 MeV energies, as measured by the Solar Electron and Proton Telescope (SEPT) instruments aboard the twin Solar Terrestrial Relations Observatory (STEREO) spacecraft. Methods. We employ an online STEREO in situ shock catalog that lists all shocks observed between 2007 and mid 2014 (observed by STEREO A) and until end of 2013 (observed by STEREO B). In total 475 shocks are listed. To determine the particle acceleration efficiency of these shocks, we analyze the associated intensity increases (shock spikes) during the shock crossings. For the near-relativistic electrons, we take into account the is...

  13. Motion sickness and otolith sensitivity - A pilot study of habituation to linear acceleration

    Potvin, A. R.; Sadoff, M.; Billingham, J.

    1977-01-01

    Astronauts, particularly in Skylab flights, experienced varying degrees of motion sickness lasting 3-5 days. One possible mechanism for this motion sickness adaptation is believed to be a reduction in otolith sensitivity with an attendant reduction in sensory conflict. In an attempt to determine if this hypothesis is valid, a ground-based pilot study was conducted on a vertical linear accelerator. The extent of habituation to accelerations which initially produced motion sickness was evaluated, along with the possible value of habituation training to minimize the space motion sickness problem. Results showed that habituation occurred for 6 of the 8 subjects tested. However, in tests designed to measure dynamic and static otolith function, no significant differences between pre- and post-habituation tests were observed. Cross habituation effects to a standard Coriolis acceleration test were not significant. It is unlikely that ground-based pre-habituation to linear accelerations of the type examined would alter susceptibility to space motion sickness.

  14. Theoretical study of self-balancing missiles. [design for maximum vertical or lateral accelerations

    Hopkins, E. J.

    1976-01-01

    A theoretical study based on linear theory is presented for two types of 'self-balancing' missiles, designed to accelerate vertically or laterally without pitching or yawing. One type of missile had a variable-incidence wing and the other type had wing flaps to provide acceleration. The main objective of this investigation is to compare the maximum available acceleration for these self-balancing missiles with that of conventional pitching-type missiles. Ten different configurations were considered. The results indicate that self-balancing missiles with either variable wing incidence or wing flaps are feasible, but that the maximum available acceleration for these missiles is less than for a conventional pitching-type missile having the same wing and tail surfaces.

  15. Design of an electromagnetic accelerator for turbulent hydrodynamic mix studies. Revision 1

    Susoeff, A.R.; Hawke, R.S.; Morrison, J.J.; Dimonte, G.; Remington, B.A.

    1994-03-01

    An electromagnetic accelerator in the form of a linear electric motor (LEM) has been designed to achieve controlled acceleration profiles of a carriage containing hydrodynamically unstable fluids for the investigation of the development of turbulent mix. Key features of the design include: (1) independent control of acceleration, deceleration and augmentation currents to provide a variety of acceleration-time profiles, (2) a robust support structure to minimized deflection and dampen vibration which could create artifacts in the data interfering with the intended study and (3) a compliant, non-arcing solid armature allowing optimum electrical contact. Electromagnetic modeling codes were used to optimize the rail and augmentation coil positions within the support structure framework. Design of the driving armature and the dynamic electromagnetic braking system is based on results of contemporary studies for non-arcing sliding contact of solid armatures. A 0.6MJ electrolytic capacitor bank is used for energy storage to drive the LEM. This report will discuss a LEM and armature design which will accelerate masses of up to 3kg to a maximum of about 3000g{sub o}, where g{sub o} is acceleration due to gravity.

  16. SWFSC/MMTD/ETP: Chase Encirclement Stress Studies (CHESS) 2001

    National Oceanic and Atmospheric Administration, Department of Commerce — The CHase Encirclement Stress Studies (CHESS) are part of a comprehensive research program designed to investigate the status of dolphin stocks that are involved in...

  17. A STUDY OF ANXIETY AND STRESS OF SPORTSPERSONS

    Quadri Syed Javeed

    2014-01-01

    Aim of the study was to find out the relationship anxiety and stress of sportspersons. Hypothesis: There will be no correlation between anxiety and stress of sportspersons. Sample: For the present study 100 Sample were belongings to Jalna and Aurangabad, 100 subjects were included of various games sportsmen i.e . Football, hockey, cricket, tennis and runner. The age range of subjects was 18-25 years. Purposive non-probability sampling technique was used. Tools: 1) Sports Anxie...

  18. A Comprehensive Review of Accelerated Life Test

    ZHANG Chun-hua; WANG Ya-shun; CHEN Xun; WEN Xi-sen

    2005-01-01

    Accelerated life test (ALT) is an important branch of reliability test and is a focus of research both for statisticians and reliability engineers. The paper outlines the four topics of study embodied in ALT: statistical analysis of constant-stress test, step-stress test and progressive stress test, and optimal design of ALT. It gives a general review of engineering applications of ALT, and points out some possible directions in ALT, gives some suggestions for further study.

  19. New, More Authentic Model for AIDS Will Accelerate Studies | Poster

    By Frank Blanchard, Staff Writer, and Jeff Lifson, Guest Writer Researchers are working to develop a more authentic animal model of human immunodeficiency virus (HIV) infection and AIDS that is expected to speed up studies of experimental treatments and vaccines.

  20. Accelerator research studies: Technical progress report, June 1, 1988--May 31, 1989

    This report discusses research progress in the following general topics: Study of transport and longitudinal compression of intense, high-brightness beams; study of collective ion acceleration by intense electron beams and pulse powered plasma focus; and study of microwave sources and parameter scaling for high-frequency electron-positron supercollider linacs

  1. Accelerator research studies. Final report, June 1, 1990--November 30, 1991

    The program consisted of the following three tasks: TASK A, ''Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams,'' TASK B, ''Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams,'' and TASK C, ''Study of a Gyroklystron High-Power Microwave Source for Linear Colliders.''

  2. Studies of a hybrid Trojan Horse wakefield accelerator with high transformer ratio

    Cook, Nathan; Bruhwiler, David; Hidding, Bernhard; Vay, Jean-Luc; Webb, Stephen

    2015-11-01

    Plasma wakefield acceleration uses relativistic high-charge electron bunches to generate a plasma blowout supporting intense electric fields for trapping and acceleration. Dramatic improvements in emittance, peak current and brightness are achievable through laser-controlled ionization in the plasma blowout, which is the premise of the Trojan Horse approach. The hybrid Trojan Horse concept extends this approach to use the output beam from a laser plasma accelerator to drive a Trojan Horse, resulting in a compact system that can produce higher brightness bunches with order-of-magnitude lower energy spread. We are exploring the use of multiple, shaped laser pulses to resonantly inject a shaped electron drive bunch. The resulting output bunch could generate wakes in PWFA or beam-driven dielectric structures with transformer ratios of 5 to 10 or larger. Hence, a hybrid Trojan Horse accelerator with bunch shaping may provide a compact source of nC bunches that can drive a variety of systems for studying high-gradient wakefields and lepton acceleration. Initial work will use previously simulated electron bunches from a laser plasma accelerator to drive the plasma wakefield stage. We present preliminary results from simulations using the parallel, particle-in-cell framework Warp. Work supported by the U.S. Department of Energy, Office of High Energy Physics, under Award Number DE-SC0013855.

  3. Study of charged particle acceleration by magnetic reconnection in a plasma

    M Mehdizade

    2016-02-01

    Full Text Available Magnetic reconnection, which occurs in high conducting plasmas, changes the topology of magnetic field lines and converts magnetic energy into the kinetic and thermal energy of plasma and also accelerates charged particles. This phenomenon plays an important role in changing the dynamic of laboratory and space plasmas such as fusion tokamaks and sun’s corona. The electric and magnetic fields generated by magnetic reconnection result in acceleration and drift motion of charged particles. Therefore, charged particles, depending on their injection position and initial kinetic energy, can be accelerated and escape or can be trapped in magnetic fields. In this study by considering different injection positions and initial kinetic energies, we investigate how a particle (proton is accelerated or trapped. Our numerical analyses show that the spine structure for three-dimensional magnetic reconnection can be considered as a potential mechanism for particle acceleration. In this model, a proton can be accelerated up to a few MeV within a few milliseconds. The particle’s trajectory and final kinetic energy strongly depend on its injection position.

  4. Evaluation of microwave oven heating for prediction of drug-excipient compatibilities and accelerated stability studies

    Schou-Pedersen, Anne Marie V; Østergaard, Jesper; Cornett, Claus;

    2015-01-01

    , if a microwave oven is applicable for accelerated drug stability testing. Chemical interactions were investigated in three selected model formulations of drug and excipients regarding the formation of ester and amide reaction products. The accelerated stability studies performed in the microwave oven using......, and sorbic acid. The model formulations were representative for oral solutions (co-solvents), parenteral solutions (buffer species) and solid dosage forms (organic acids applicable for solubility enhancement). The DoE studies showed overall that the same impurities were generated by microwave oven heating...... leading to temperatures between 150°C and 180°C as compared to accelerated stability studies performed at 40°C and 80°C using a conventional oven. Ranking of the reactivity of the excipients could be made in the DoE studies performed at 150-180°C, which was representative for the ranking obtained after...

  5. Design studies of a high-current radiofrequency quadrupole for accelerator-driven systems programme

    S V L S Rao; P Singh

    2010-02-01

    A 3 MeV, 30 mA radiofrequency quadrupole (RFQ) accelerator has been designed for the low-energy high-intensity proton accelerator (LEHIPA) project at BARC, India. The beam and cavity dynamics studies were performed using the computer codes LIDOS, TOUTATIS, SUPERFISH and CST microwave studio. We have followed the conventional design technique with slight modifications and compared that with the equipartitioned (EP) type of design. The sensitivity of the RFQ to the variation of input beam Twiss–Courant parameters and emittance has also been studied. In this article we discuss both design strategies and the details of the 3D cavity simulation studies.

  6. Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams.

    Raschke, S; Spickermann, S; Toncian, T; Swantusch, M; Boeker, J; Giesen, U; Iliakis, G; Willi, O; Boege, F

    2016-01-01

    Ultra-short proton pulses originating from laser-plasma accelerators can provide instantaneous dose rates at least 10(7)-fold in excess of conventional, continuous proton beams. The impact of such extremely high proton dose rates on A549 human lung cancer cells was compared with conventionally accelerated protons and 90 keV X-rays. Between 0.2 and 2 Gy, the yield of DNA double strand breaks (foci of phosphorylated histone H2AX) was not significantly different between the two proton sources or proton irradiation and X-rays. Protein nitroxidation after 1 h judged by 3-nitrotyrosine generation was 2.5 and 5-fold higher in response to conventionally accelerated protons compared to laser-driven protons and X-rays, respectively. This difference was significant (p < 0.01) between 0.25 and 1 Gy. In conclusion, ultra-short proton pulses originating from laser-plasma accelerators have a similar DNA damaging potential as conventional proton beams, while inducing less immediate nitroxidative stress, which probably entails a distinct therapeutic potential. PMID:27578260

  7. Study of stress birefringence for 193-nm immersion photomasks

    Cotte, Eric; Selle, Michael; Bubke, Karsten; Teuber, Silvio

    2005-06-01

    The goal of the present study was to investigate and quantify reticle stress birefringence in exposure conditions. Birefringence can arise in fused silica photomask substrates due to their state of stress, and cause optical effects such as phase front distortion, ray bifurcation, and polarization changes. These effects potentially produce image blurring and illumination non-uniformity, leading to lower resolution and CD variations, respectively. The main sources of substrate stress studied were the absorber stack, the mounting of a pellicle, and the impact of initial reticle bow when chucking in an exposure tool. Jones calculus was used to relate birefringence at discrete locations in the reticle, derived from the state of stress, to the net birefringence experienced by light passing through the mask. Experimentally-obtained birefringence data as well as analytical calculations of stress birefringence caused by known states of stress were used to validate the models. These results can then be compared to photomask birefringence specifications or employed in optical simulations to determine the precise impact of this substrate stress birefringence.

  8. Parametric study of transport beam lines for electron beams accelerated by laser-plasma interaction

    Scisciò, M.; Lancia, L.; Migliorati, M.; Mostacci, A.; Palumbo, L.; Papaphilippou, Y.; Antici, P.

    2016-03-01

    In the last decade, laser-plasma acceleration of high-energy electrons has attracted strong attention in different fields. Electrons with maximum energies in the GeV range can be laser-accelerated within a few cm using multi-hundreds terawatt (TW) lasers, yielding to very high beam currents at the source (electron bunches with up to tens-hundreds of pC in a few fs). While initially the challenge was to increase the maximum achievable electron energy, today strong effort is put in the control and usability of these laser-generated beams that still lack of some features in order to be used for applications where currently conventional, radio-frequency (RF) based, electron beam lines represent the most common and efficient solution. Several improvements have been suggested for this purpose, some of them acting directly on the plasma source, some using beam shaping tools located downstream. Concerning the latter, several studies have suggested the use of conventional accelerator magnetic devices (such as quadrupoles and solenoids) as an easy implementable solution when the laser-plasma accelerated beam requires optimization. In this paper, we report on a parametric study related to the transport of electron beams accelerated by laser-plasma interaction, using conventional accelerator elements and tools. We focus on both, high energy electron beams in the GeV range, as produced on petawatt (PW) class laser systems, and on lower energy electron beams in the hundreds of MeV range, as nowadays routinely obtained on commercially available multi-hundred TW laser systems. For both scenarios, our study allows understanding what are the crucial parameters that enable laser-plasma accelerators to compete with conventional ones and allow for a beam transport. We show that suitable working points require a tradeoff-combination between low beam divergence and narrow energy spread.

  9. Accelerator research studies: Technical progress report for the period June 1, 1986 to May 31, 1987

    Progress is reported in the study of instabilities and emittance growth in periodic focusing systems for intense beams, collective ion acceleration by intense electron beams and pulse-powered plasma focus, and microwave sources and parameter scaling for high-frequency linacs. Results of a solenoid lens realignment are reported. Theoretical work with particle simulation codes is underway. Laser-controlled collective ion acceleration was demonstrated, a time-resolved Thomson spectrometer was developed, and theoretical studies have led to the development of improved analytical and simulation models describing the equilibrium state and the collective acceleration mechanism in an electron beam with co-moving ions. Progress is reported in the development of a gyroklystron electron gun, and theoretical work on frequency scaling and wakefield effects resulting in codes for quick evaluation of different parameter regimes for electron-positron colliders is discussed. Studies of quadrupole wakefield effects have commenced

  10. Study of ultra-clean surfaces for accelerator structures

    For a TeV energy physics R and D on electron/positron linear colliders has been conducted hard at many laboratories from technologies of both normal conducting and superconducting. The high field gradient issue is a key to realize such a machine. Field emission limits seriously field gradient of rf cavities. Its cure is to eliminate particle contamination on cavity surfaces. It is a common issue in both normal conducting and superconducting cavities. We have started to study ultra-clean surfaces of niobium and copper applying semiconductor technologies. In this paper several results by various rinsing methods are presented and its relation with cavity performance is discussed. (author)

  11. Preliminary Study on Conducting Experiments for Assessment of Secondary Stresses

    In order to validate the new procedure for assessment of cracks in ductile materials with presence of high secondary stresses, access to the experimental results is needed. Such experimental results are very limited in the published literature. In this report, different test options are studied in order to find a proper test program to study the effects of secondary stresses at high levels of primary stresses. These options consider the use of thermal transients or welding residual stresses in the test program. A total of 36 different cases considering crack configuration, type of thermal transient and the level of mechanical loading are studied here. The fracture assessments of these cases are conducted based on the R6-method. Based on the assessment results conducted in this study, the following options are proposed for conducting the test program: Option 1: To use a thermal transient with T0 = 200 deg C and h = 5 kW/m2 deg C on edge surface cracked plates with a/t = 0.3 subjected to a mechanical bending of σb/σY > 0.8. Option 2: To use welding residual stresses on edge surface cracked plates with a/t 0.3 subjected to a mechanical bending of σb/σY > 0.6. Option 3: To use mechanically induced residual stresses (in-plane compression) in edge surface cracked specimens subjected to a mechanical bending

  12. A crystal routine for collimation studies in circular proton accelerators

    Mirarchi, D.; Hall, G.; Redaelli, S.; Scandale, W.

    2015-07-01

    A routine has been developed to simulate interactions of protons with bent crystals in a version of SixTrack for collimation studies. This routine is optimized to produce high-statistics tracking simulations for a highly efficient collimation system, like the one of the CERN Large Hadron Collider (LHC). The routine has recently been reviewed and improved through a comparison with experimental data, benchmarked against other codes and updated by adding better models of low-probability interactions. In this paper, data taken with 400 GeV/c proton beams at the CERN-SPS North Area are used to verify the prediction of the routine, including the results of a more recent analysis.

  13. Materials analysis in archaeometrical studies at Bucharest accelerators

    The scientific analysis of archaeological objects ideally requires the availability of methods, which are simultaneously non-destructive, fast, universal, versatile, sensitive and multielemental. Analyses of source materials combined with analyses of the objects could distinguish from pieces produced in different regions. Our purpose is to help archaeologists to identify objects provenance (workshops, technologies, mines) and to explain different commercial, military and political aspects. For numismatic research, we used 241Am source based XRF (X-ray Fluorescence) and 4.7 MeV alphaparticles induced PIXE (Particle Induced X-ray Emission) methods. Coins emitted by Histria (Greek colony, IVth - IIIrd Century B.C.), late Roman Empire, Byzantine Empire (Xth - XIth Century) were examined. For ceramics and glasses studies three methods were used: 3 MeV protons PIXE, 241Am source based XRF and FNAA (Fast Neutron Activation Analysis). Using a fast neutrons beam, some light elements can be determined: Al, Mg, Na, Si, but also Ca, Ti, Fe, Zn, Cd, In, Sn, Sb, Ba, Pb. The above mentioned methods are complementary and they work better together. Some results on various ceramics objects from Romanian sites (glaze and painting agents) are presented. For glasses, the problem is to identify coloring agents, decolorants, opacifiers and fining agents. Some results on medieval and XVIIIth Century samples founded in South-Eastern Romania are presented. The last example we present is a study on ancient Dacian gold coins. The methods used were XRF and PAA (Proton Activation Analysis). Three groups of coins with different composition were found, corresponding to simple, complex and no monogram pieces. Possible historical conclusions are discussed. (author)

  14. Studies of Coupled Cavity Linac (CCL) Accelerating Structures with 3-D Codes

    Spalek, G; Smith, P D; Greninger, P T; Charman, C M

    2000-01-01

    The cw CCL being designed for the Accelerator Production of Tritium (APT) project accelerates protons from 96MeV to 211MeV. It consists of 99 segments each containing up to seven accelerating cavities. Segments are coupled by intersegment coupling cavities and grouped into supermodules. The design method needs to address not only basic cavity sizing for a given coupling and pi/2 mode frequency, but also the effects of high power densities on the cavity frequency, mechanical stresses, and the structure's stop band during operation. On the APT project, 3-D RF (Ansoft Corp.'s HFSS) and coupled RF/structural (Ansys Inc.'s ANSYS) codes are being used to develop tools to address the above issues and guide cooling channel design. The code's predictions are being checked against available low power Aluminum models. Stop band behavior under power will be checked once the tools are extended to CCDTL structures that have been tested at high power. A summary of calculations made to date and agreement with measured result...

  15. Studies of coupled cavity LINAC (CCL) accelerating structures with 3-D codes

    The cw CCL being designed for the Accelerator Production of Tritium (APT) project accelerates protons from 96 MeV to 211 MeV. It consists of 99 segments each containing up to seven accelerating cavities. Segments are coupled by intersegment coupling cavities and grouped into supermodules. The design method needs to address not only basic cavity sizing for a given coupling and pi/2 mode frequency, but also the effects of high power densities on the cavity frequency, mechanical stresses, and the structure's stop band during operation. On the APT project, 3-D RF (Ansoft Corp.'s HFSS) and coupled RF/structural (Ansys Inc.'s ANSYS) codes are being used. to develop tools to address the above issues and guide cooling channel design. The code's predictions are being checked against available low power Aluminum models. Stop band behavior under power will be checked once the tools are extended to CCDTL structures that have been tested at high power. A summary of calculations made to date and agreement with measured results will be presented

  16. Laughter and Stress Relief in Cancer Patients: A Pilot Study

    Kim, S. H.; Kim, Y H; Kim, H. J.

    2015-01-01

    The purpose of this study was to examine the effect of a therapeutic laughter program and the number of program sessions on anxiety, depression, and stress in breast cancer patients. A randomized controlled trial was conducted involving 31 patients who received four sessions of therapeutic laughter program comprised and 29 who were assigned to the no-program control group. Scores for anxiety, depression, and stress were measured using an 11-point numerical rating scale. While no change was de...

  17. Police Department Personnel Stress Resilience Training: An Institutional Case Study

    Weltman, Gershon; Lamon, Jonathan; Freedy, Elan; Chartrand, Donald

    2014-01-01

    The objective of this case study was to test the impact in law enforcement personnel of an innovative self-regulation and resilience building program delivered via an iPad (Apple Inc, Cupertino, California) app and personal mentoring. The Stress Resilience Training System (SRTS) app includes training on stress and its effects, HRV coherence biofeedback, a series of HeartMath self-regulation techniques (The Institute of HeartMath, Boulder Creek, California), and HRV-controlled games. The stres...

  18. Accelerator Research Studies. Annual report for June 1, 2003 - May 31, 2004

    O' Shea, P. G.; Reiser, M.; Granatstein, V. L.; Lawson, W.; Haber, I.; Kishek, R.

    2004-01-23

    The report provides a summary progress on three tasks: Task A: Study of the Physics of Space-Charge Dominated Beams for Advanced Accelerator Applications; Task B: Studies of High-Power Gyroklystrons and Application to Linear Colliders; and, Task C: Theory and Simulation of the Physics Space-Charge Dominated Beams

  19. Accelerator transmutation studies at Los Alamos with LAHET, MCNP, and CINDER'90

    Versions of the CINDER code have been used over three decades for determination of reactor fuel inventories and aggregate neutron absorption and radioactive decay properties. The CINDER'90 code, an evolving version which requires no predetermined nuclide chain structure, is suitable for a wider range of transmutation problems including those treated with older versions. In recent accelerator transmutation studies, the CINDER'90 code has been linked with the LAHET Code System (LCS) and, for high-energy calculations, with SUPERHET. A description of the nature of these linked calculational tools is given; data requirements for the transmutation studies are described; and, examples of linked calculations are described for some interesting accelerator applications

  20. Stability of CIGS Solar Cells and Component Materials Evaluated by a Step-Stress Accelerated Degradation Test Method: Preprint

    Pern, F. J.; Noufi, R.

    2012-10-01

    A step-stress accelerated degradation testing (SSADT) method was employed for the first time to evaluate the stability of CuInGaSe2 (CIGS) solar cells and device component materials in four Al-framed test structures encapsulated with an edge sealant and three kinds of backsheet or moisture barrier film for moisture ingress control. The SSADT exposure used a 15oC and then a 15% relative humidity (RH) increment step, beginning from 40oC/40%RH (T/RH = 40/40) to 85oC/70%RH (85/70) as of the moment. The voluminous data acquired and processed as of total DH = 3956 h with 85/70 = 704 h produced the following results. The best CIGS solar cells in sample Set-1 with a moisture-permeable TPT backsheet showed essentially identical I-V degradation trend regardless of the Al-doped ZnO (AZO) layer thickness ranging from standard 0.12 μm to 0.50 μm on the cells. No clear 'stepwise' feature in the I-V parameter degradation curves corresponding to the SSADT T/RH/time profile was observed. Irregularity in I-V performance degradation pattern was observed with some cells showing early degradation at low T/RH < 55/55 and some showing large Voc, FF, and efficiency degradation due to increased series Rs (ohm-cm2) at T/RH ≥ 70/70. Results of (electrochemical) impedance spectroscopy (ECIS) analysis indicate degradation of the CIGS solar cells corresponded to increased series resistance Rs (ohm) and degraded parallel (minority carrier diffusion/recombination) resistance Rp, capacitance C, overall time constant Rp*C, and 'capacitor quality' factor (CPE-P), which were related to the cells? p-n junction properties. Heating at 85/70 appeared to benefit the CIGS solar cells as indicated by the largely recovered CPE-P factor. Device component materials, Mo on soda lime glass (Mo/SLG), bilayer ZnO (BZO), AlNi grid contact, and CdS/CIGS/Mo/SLG in test structures with TPT showed notable to significant degradation at T/RH ≥ 70/70. At T/RH = 85/70, substantial blistering of

  1. Design study of Nb3Sn impregnated advanced accelerator dipole magnet. Final report

    The invention and development of particle accelerators and the associated technology has had a profound impact upon the progress which has been achieved in US Science and Technology. Improvements in accelerator performance to date have paced the science of particle physics. Equivalent beam energies have increased 107 times over the past 50 years. Reduction in unit energy costs of 106 times has also been realized over the same period. While both of these figures represent spectacular accomplishments, the cost reductions have not kept pace with energy increase. As a result, a limitation has had to be placed on the number and diversity of high energy accelerator facilities. Further limitations can be expected if the cost/energy trends continue. The problem then becomes one of achieving an increased rate of unit energy cost reduction while maintaining performance improvement. The solution involves: full exploitation of the potential of the current accelerator technologies, and invention of entirely new technologies and methods. The present study falls into the first of these approaches in which General Electric's Advanced Energy Programs Department in Schenectady, NY was asked to assess the feasibility of applying its proven epoxy impregnation process to high field accelerator magnets. This report details the results of Phase 1 of this study

  2. Post-acceleration study for neutrino super-beam at CSNS

    WU Yang; TANG Jing-Yu

    2013-01-01

    A post-acceleration system based on the accelerators at CSNS (China Spallation Neutron Source) is proposed to build a super-beam facility for neutrino physics.Two post-acceleration schemes,one using superconducting dipole magnets in the main ring and the other using room temperature magnets,have been studied,both to achieve the final proton energy of 128 GeV and the beam power of 4 MW by taking 10% of the CSNS beam from the neutron source.The main design features and the comparison for the two schemes are presented.The CSNS super-beam facility will be very competitive in long-baseline neutrino physics studies,compared with other super-beam facilities proposed in the world.

  3. Usefulness of salivary alpha amylase as a biomarker of chronic stress and stress related oral mucosal changes ' a pilot study

    Vineetha, Ravindranath; Pai, Keerthilatha M; Vengal, Manoj; Gopalakrishna, Kodyalamoole; Narayanakurup, Dinesh

    2014-01-01

    Introduction: Salivary biomarkers are suggested to provide a reliable, noninvasive and objective measurement of chronic psychosocial stress and helps in assessment of pivotal role of stress in causation or precipitation of multitude of health problems. Objectives: To evaluate the usefulness of salivary alpha amylase activity as an objective indicator of chronic stress and to find out any correlation between stress- related mucosal complaints and its levels. Study Design: Study was conducted a...

  4. Diabetes och stress : en teoretisk studie om sambandet mellan diabetes och stress

    Backlund, Gunilla

    2013-01-01

    Syftet med denna studie är att utgående från tidigare forskningar och undersökningar undersöka upplevd stress och dess påverkan på blodsocker balansen. Syftet är också att undersöka hur en person med diabetes kan förebygga stress och förhöjda blodsockervärden genom en god egenvård. Egenvården och patientens välmående i förhållande till blodsockernivån undersöks också. Problempreciseringen för studien var: Hur påverkas patientens blodsockerbalans av stress? Hur kan patienter med diabetes påver...

  5. Stress Reactivity to an Electronic Version of the Trier Social Stress Test: A Pilot Study

    Sage E Hawn

    2015-05-01

    Full Text Available Social stressors that rely on the inclusion of confederates (i.e., Trier Social Stress Test; TSST are often used in clinical laboratory research paradigms to elicit a measurable stress response in participants. Although effective, the TSST is labor intensive and may introduce error variance as a function of confederate race, gender, and/or response characteristics. The present study aimed to develop and validate an electronic version of the TSST (e-TSST. The primary aim was to compare the e-TSST to an e-neutral control condition; the exploratory aim was to compare the magnitude of stress response elicited by the e-TSST to that elicited by the traditional TSST. Forty-three healthy adults were randomized to the e-TSST or e-neutral condition. Subjective (participant-rated distress and objective (cortisol, heart rate and blood pressure indices of stress were collected prior to, and multiple times following, the stressor. Using archival data collected from 19 healthy participants exposed to the traditional TSST in a prior study, stress reactivity was compared between the electronic and traditional versions of the TSST. The e-TSST elicited significant increases in all measures of stress reactivity compared to the e-neutral condition, with the exception of heart rate (HR. Results showed that the magnitude of subjective distress, BP, and HR responses elicited by the e-TSST did not differ significantly from that elicited by the traditional TSST. The traditional TSST elicited significantly higher cortisol than the e-TSST. Although these findings provide initial support for the development of electronic versions of the TSST, further refinement of the e-TSST is warranted prior to broad adoption of this technology. A refined, reliable e-TSST could allow for increased utilization of the TSST by enhancing convenience, reducing labor costs, and limiting potential error variance introduced by human confederates.

  6. Efficiency of particle acceleration at interplanetary shocks: Statistical study of STEREO observations

    Dresing, N.; Theesen, S.; Klassen, A.; Heber, B.

    2016-04-01

    Context. Among others, shocks are known to be accelerators of energetic charged particles. However, many questions regarding the acceleration efficiency and the required conditions are not fully understood. In particular, the acceleration of electrons by shocks is often questioned. Aims: In this study we determine the efficiency of interplanetary shocks for particle acceleration efficiency of these shocks, we analyze the associated intensity increases (shock spikes) during the shock crossings. For the near-relativistic electrons, we take into account the issue of possible ion contamination in the SEPT instrument. Results: The highest acceleration efficiency is found for low energy ions (0.1 MeV), which show a shock-associated increase at 27% of all shocks. The 2 MeV ions show an associated increase only during 5% of the shock crossings. In the case of the electrons, the shocks are nearly ineffective. Only five shock-associated electron increases were found, which correspond to only 1% of all shock crossings.

  7. YOUNG SUPERNOVAE AS EXPERIMENTAL SITES FOR STUDYING THE ELECTRON ACCELERATION MECHANISM

    Radio emissions from young supernovae (∼<1 year after the explosion) show a peculiar feature in the relativistic electron population at a shock wave, where their energy distribution is steeper than typically found in supernova remnants and than that predicted from the standard diffusive shock acceleration (DSA) mechanism. This has been especially established for the case for a class of stripped envelope supernovae (SNe IIb/Ib/Ic), where a combination of high shock velocity and low circumstellar material density makes it easier to derive the intrinsic energy distribution than in other classes of SNe. We suggest that this apparent discrepancy reflects a situation where the low energy electrons, before being accelerated by the DSA-like mechanism, are responsible for the radio synchrotron emission from young SNe, and that studying young SNe sheds light on the still-unresolved electron injection problem in the acceleration theory of cosmic rays. We suggest that the electron's energy distribution could be flattened toward high energy, most likely around 100 MeV, which marks a transition from inefficient to efficient acceleration. Identifying this feature will be a major advance in understanding the electron acceleration mechanism. We suggest two further probes: (1) millimeter/submillimeter observations in the first year after the explosion and (2) X-ray observations at about one year and thereafter. We show that these are reachable by ALMA and Chandra for nearby SNe.

  8. An alternative time marker for the study of the uniform and uniformly accelerated movements

    Osmar Henrique Moura da Silva

    2003-01-01

    Full Text Available This work presents a type of time marker set up with materials of low cost for the study of uniform movements as well as those accelerated by gravitacional force. A mechanism used to measure its frequency is coupled to it in order to find the approximate value of the acceleration of the local gravity. The experiment, that is adapted to be used during a kinematics class, can also be presented by the students at a science fair, for being a stimulating factor as it involves the students’ participation in its construction.

  9. A Study on the Vibration of the Charging Belt in an Electrostatic Accelerator

    2001-01-01

    The vibration of the charging belt in an electrostatic accelerator has intense influences on the accelerator operation. A calculating model was set up in this paper to study the belt vibration. The results show that the belt tension, belt velocity and belt current all contribute to the belt vibration. There is an optimal relationship among the three factors by which the belt would run most smoothly. There exists a minimum value of optimal tension for various belt velocities. The vibrating frequency of the is generally around several Hz.

  10. Experimental study on resonance relativistic SHF generators on the base of linear induction electron accelerator

    The results of studies on relativistic SHF-generators - orotron and gyrotron for obtaining data on the quality of a high-current electron beam shaped in the section of a linear induction accelerator are given. Axisymmetric resonators as sections of weak-irregular waveguides were used in both generators. Stable generation of short-wave radiation of 15-20 MW at the efficiency of 5-7% SHF pulse duration of 50 ns was obtained in the orotron at the wave length of 8.5 mm and current of 600 A. Stable generation of 7-10 MW SHF-radiation at the efficiency of 3-5% and pulse duration of 150 ns was observed in the gyrotron at the wave length of 12 mm. Under further acceleration in the following sections of the accelerator the electron beam may be used for obtaining radiation of shorter waves

  11. Accelerator and Ion Beam Tradeoffs for Studies of Warm Dense Matter

    Barnard, John J; Callahan, Debra; Davidson, Ronald C; Friedman, Alex; Grant-Logan, B; Grisham, Larry; Lee, Edward; Lee, Richard; Olson, Craig; Rose, David; Santhanam, Parthiban; Sessler, Andrew M; Staples, John W; Tabak, Max; Welch, Dale; Wurtele, Jonathan; Yu, Simon

    2005-01-01

    One approach to heat a target to "Warm Dense Matter" conditions (similar, for example, to the interiors of giant planets or certain stages in Inertial Confinement Fusion targets), is to use intense ion beams as the heating source. By consideration of ion beam phase space constraints, both at the injector, and at the final focus, and consideration of simple equations of state, approximate conditions at a target foil may be calculated. Thus target temperature and pressure may be calculated as a function of ion mass, ion energy, pulse duration, velocity tilt, and other accelerator parameters. We examine the variation in target performance as a function of various beam and accelerator parameters, in the context of several different accelerator concepts, recently proposed for WDM studies.

  12. Accelerated hydrolysis of substituted cellulose for potential biofuel production: kinetic study and modeling.

    Mu, Bingnan; Xu, Helan; Yang, Yiqi

    2015-11-01

    In this work, kinetics of substitution accelerated cellulose hydrolysis with multiple reaction stages was investigated to lay foundation for mechanism study and molecular design of substituting compounds. High-efficiency hydrolysis of cellulose is critical for cellulose-based bioethanol production. It is known that, substitution could substantially decrease activation energy and increase reaction rate of acidic hydrolysis of glycosidic bonds in cellulose. However, reaction kinetics and mechanism of the accelerated hydrolysis were not fully revealed. In this research, it was proved that substitution therefore accelerated hydrolysis only occurred in amorphous regions of cellulose fibers, and was a process with multiple reaction stages. With molar ratio of substitution less than 1%, the overall hydrolysis rate could be increased for around 10 times. We also quantified the relationship between the hydrolysis rate of individual reaction stage and its major influences, including molar ratio of substitution, activation energy of acidic hydrolysis, pH and temperature. PMID:26253917

  13. A study of stress affecting police officers in Lithuania.

    Zukauskas, Gediminas; Ruksenas, Osvaldas; Burba, Benjaminas; Grigaliuniene, Viktorija; Mitchell, Jeffrey T

    2009-01-01

    This research study aims to identify the key stresses encountered by police officers in Lithuania in 2003. A questionnaire was distributed to officers working in police departments throughout Lithuania. The 2003 results were a compared with a similar study carried out among male and female police officers in Lithuania 1999. The stressors determined to have the greatest negative effects were administrative problems, family problems, and an ineffective criminal justice system. Identified consequences of police stress included depression, alcoholism, physical illness, and suicide. Dealing with stressful situations led to more frequent physical illness in female police officers and higher alcohol consumption in male police officers. This paper confirms the findings of previous studies. It adds to the knowledge of the unique stresses affecting police officers. It briefly explores the consequences of stress in police work. Since the study represents a small sample of the 15,000 police officers in Lithuania, caution is urged in the application of the findings to other police departments. PMID:20524505

  14. Experimental study of liquid-metal target designs of accelerating-controlled systems

    Models of a liquid-metal target of an accelerator-controlled system have been experimentally studied at the Nizhny Novgorod State Technical University to develop an optimal design of the flow part of the target. The main explored variants of liquid-metal targets are: Design with a diaphragm (firm-and-impervious plug) mounted on the pipe tap of particle transport from the accelerator cavity to the working cavity of the liquid-metal target. Design without a diaphragm on the pipe tab of particle transport from the accelerator. The study was carried out in a high-temperature liquid-metal test bench under the conditions close to full-scale ones: the temperature of the eutectic lead-bismuth alloy was 260degC - 400degC, the coolant mass flow was 5-80 t/h, and the rarefaction in the gas cavity was 105 Pa, the coefficient of geometric similarity equal to 1. The experimental studies of hydrodynamic characteristics of flow parts in the designs of targets under full-scale conditions indicated high efficiency of a target in triggering, operating, and deactivating modes. Research and technology instructions for designs of the flow part of the liquid-metal target, the target design as a whole, and the target circuit of accelerator-controlled systems were formulated as a result of the studies. (author)

  15. Does recombinant human erythropoietin accelerate correction of post-ulcer-bleeding anaemia A pilot study

    Ladas, Spiros D.; Polymeros, Dimitrios; Pagonis, Thomas; Triantafyllou, Konstantinos; Paspatis, Gregorios; Hatziargiriou, Maria; Raptis, Sotirios A.

    2004-01-01

    AIM: Anaemia caused by acute upper gastrointestinal bleeding is treated with blood transfusion or iron, but patients usually face a two-month recovery period from post-haemorrhage anaemia. This prospective, randomised, open, pilot study was designed to investigate whether recombinant human erythropoietin (Epoetin) therapy accelerate haematocrit increase in the post-bleeding recovery period.

  16. Study of cerenkov radiation. Production of γ rays by electron accelerators

    This study is a critical comparison of the theories of Bremsstrahlung. Experimental results obtained by the production of γ radiation with electron accelerators are compared to the theoretical results in order to estimate the extent to which the various theories are valid. (author)

  17. A study of the high vacuum engineering for the accelerator tube construction has performed

    Failure of the accelerator tube vacuum systems due to construction and physical chemistry aspect are reported in this study. The problem solving are presented in this paper, where the results of this engineering concepts are met with the requirement of the technical specifications. (author)

  18. The Study of Two-Dimensional Oscillations Using a Smartphone Acceleration Sensor: Example of Lissajous Curves

    Tuset-Sanchis, Luis; Castro-Palacio, Juan C.; Gómez-Tejedor, José A.; Manjón, Francisco J.; Monsoriu, Juan A.

    2015-01-01

    A smartphone acceleration sensor is used to study two-dimensional harmonic oscillations. The data recorded by the free android application, Accelerometer Toy, is used to determine the periods of oscillation by graphical analysis. Different patterns of the Lissajous curves resulting from the superposition of harmonic motions are illustrated for…

  19. Nonlinear stability of Kelvin-Helmholtz waves in magnetic fluids stressed by a time-dependent acceleration and a tangential magnetic field

    El-Dib, Yusry O.

    1996-04-01

    The nonlinear stability of surface waves propagating between two superposed streaming magnetic fluids is investigated. The fluids are stressed by a constant tangential magnetic field and a vertical periodic acceleration. The solution employs the method of multiple scales. Owing to the periodicity, resonant cases appear. Two parametrically nonlinear Schrödinger equations are derived for the resonant cases to describe the elevation of weakly nonlinear capillary waves. The standard nonlinear Schrödinger equation is satisfied for the non resonant cases. Necessary and sufficient conditions for stability are obtained. A formula for the surface elevation is obtained in each case. It is found that the magnetic field, the velocities and the frequency of the applied periodic force play dual roles in the resonant region. Investigation of the stability criterion by nonlinear perturbation shows that an increase in the acceleration frequency has a stabilizing effect. The stabilizing role of the frequency is due to the destabilizing effect of the amplitude of the periodic acceleration.

  20. A study of oxidative stress in paucibacillary and multibacillary leprosy

    Jyothi P

    2008-01-01

    Full Text Available Background: The study and assessment of oxidative stress plays a significant role in the arena of leprosy treatment. Once the presence of oxidative stress is proved, antioxidant supplements can be provided to reduce tissue injury and deformity. Aim: To study oxidative stress in paucibacillary (PB and multibacillary (MB leprosy and to compare it with that in a control group. Methods: Fifty-eight untreated leprosy patients (23 PB and 35 MB cases were studied and compared with 58 healthy controls. Superoxide dismutase (SOD level as a measure of antioxidant status; malondialdehyde (MDA level, an indicator of lipid peroxidation; and MDA/SOD ratio, an index of oxidative stress were estimated in the serum. Results: The SOD level was decreased in leprosy patients, especially in MB leprosy. The MDA level was increased in PB and MB leprosy. The MDA/SOD ratio was significantly elevated in MB patients. There was a steady increase in this ratio along the spectrum from tuberculoid to lepromatous leprosy (LL. Conclusion: There is increased oxidative stress in MB leprosy, especially in LL. This warrants antioxidant supplements to prevent tissue injury.

  1. Magnetohydrodynamic study of adiabatic supersonic and subsonic expansion accelerations in spontaneous fast magnetic reconnection

    The thermodynamic supersonic expansion acceleration mechanism associated with the spontaneous fast magnetic reconnection is studied by two-dimensional magnetohydrodynamic (MHD) simulations and the Rankine-Hugoniot analysis. The reconnection outflow jet can steadily exceed the Alfven velocity measured in the upstream magnetic field region. Such a high speed jet cannot be explained by the Petschek model. According to previous studies, when supersonic (superfast) plasma jets generated by a pair of slow shocks expand in the direction normal to the jet, the jets can be further accelerated beyond the Alfven velocity by the adiabatic supersonic expansion process. The expansion process is caused by the swelling of the plasmoid (magnetic loop). In this paper, it is theoretically shown that the sound Mach number of the reconnection jet generated by slow shocks is determined by the plasma density and beta value in the upstream magnetic field region, in which asymmetric reconnection models are also studied. Then, the theoretical prediction of the Mach number is related to the onset of the supersonic expansion acceleration process in MHD simulations. In addition, it is shown that, also when the reconnection jet is subsonic, the jet is further accelerated by the adiabatic subsonic expansion mechanism

  2. Development of a tensile testing device under ion irradiation and study on effect of stress on radiation embrittlement

    Relatively little attention has been paid to the simultaneous effects of radiation and stress on microstructural evolution related to radiation embrittlement of reactor pressure vessel steels. In the present study, Fe ion irradiation experiments were carried out for bent specimens of A533B steel using the tandem ion accelerator in the Dual-Beam Facility for Energy Science and Technology (the DuET facility) at Kyoto University to characterize hardening and microstructure evolution in reactor pressure vessel steels under irradiation and stress. A tensile testing device under ion irradiation for the DuET facility was developed and the study on effect of stress on radiation embrittlement was started using the tensile testing device. The present paper showed the dependence of the external stress on the irradiation hardening and the influence of the external stress on the microstructure evolution appeared by the irradiation experiments for the bent specimens, and introduced the detail of the tensile testing device under ion irradiation. From the obtained results, the radiation-induced hardening decreased with increasing stress to the yield strength, and application of tensile stress would control hardening by suppressing the solute cluster nucleation and growth. (author)

  3. Salivary amylase and stress during stressful environment: three Mars analog mission crews study.

    Rai, Balwant; Kaur, Jasdeep; Foing, Bernard H

    2012-06-14

    After the establishment of the space age physicians, human factors engineers, neurologist and psychologists and their special attention to work on people's capability to meet up the physical, psychological, neuroscience and interpersonal strains of working in space, it has been regarded as an issue that seeks urgent consideration. Not study was conducted on effect of simulated Mars analog environment on stress and salivary amylase. So, this study aimed to confirm whether salivary amylase is act as stress biomarker in crew members who took part in Mars analog mission in an isolated and stressful environment. The 18 crew members were selected who took part in Mars Analog Research Station, Utah. Salivary amylase was measured using a biosensor of salivary amylase monitor and State-Trait Anxiety Inventory score at pre-extravehicular activity, post-extravehicular activity and on before mission. The state and trait anxiety scores at pre-extravehicular activity for each commander were elevated as compared to after extravehicular activity. There were significant differences in the state and trait anxiety scores between before extravehicular activity and after extravehicular activity of Commander and other members, also there were significant differences in values of before-extravehicular activity between commanders and other members. There were significant differences in values of salivary amylase at before extravehicular activity and after extravehicular activity between commander group and other members. There was significant correlation between salivary amylase and state and trait anxiety scores in all groups. Measuring salivary amylase level could be useful for stress assessment of crew members and population working in a stressful and isolated environment. PMID:22554904

  4. Study of laminated anisotropic cylindrical shells sensitive to transverse stresses

    A variational method for the determination of stresses and displacements in a multilayered cylindrical shell is presented. All included materials are linearly anisotropic (monoclinic) - i.e. directional fibres reinforced materials. This study uses a functional which is derived from the potential energy of the structure. The incoming stresses are σRR, σRθ, σRZ, and the displacements are uθ and uZ. This mixed group is the main variables of the formulation. It is shown that the stationarity conditions of the functional are the equilibrium equations and the associated boundary conditions. An approximate solution can be found using a finite element method which realizes a tridimensional discretization of the structure. The program issued is a specific mean for studying the transverse shear stresses in laminated cylindrical structures. From the results obtained it can be concluded that it meets all requirements for the purposes of this range of problems. (author)

  5. Electrochemical study of stress corrosion cracking of copper alloys

    This work deals with the electrochemical study of stress corrosion of copper alloys in aqueous environment. Selective dissolution and electrochemical oxidation are two key-points of the stress corrosion of these alloys. The first part of this thesis treats of these aspects applied to Cu-Au alloys. Measurements have been performed using classical electrochemical techniques (in potentio-dynamic, potentio-static and galvano-static modes). The conditions of occurrence of an electrochemical noise is analysed using signal processing techniques. The impact on the behavior of Cu3Au are discussed. In the second part, the stress corrosion problem is addressed in the case of surface oxide film formation, in particular for Cu-Zn alloys. We have found useful to extend this study to mechanical stress oxidation mechanisms in the presence of an oscillating potential electrochemical system. The aim is to examine the influence of these new electrochemical conditions (galvano-static mode) on the behavior of stressed brass. Finally, the potential distribution at crack tip is calculated in order to compare the different observations

  6. System and safety studies of accelerator driven transmutation systems. Annual report 1998

    Wallenius, J.; Gudowski, W.; Carlsson, Johan; Eriksson, Marcus; Tucek, K. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Nuclear and Reactor Physics

    1998-12-01

    This annual report describes the accelerator-driven transmutation project conducted at the Department of Nuclear and Reactor Physics at the Royal Institute of Technology. The main results are: development of the simulation tools for accelerator-driven transmutation calculations including an integrated Monte-Carlo burnup module and improvements of neutron energy fission yield simulations, processing of the evacuated nuclear data files including preparation of the temperature dependent neutron cross-sections, development of nuclear data for a medium energy range for some isotopes, development of the models and codes for radiation damage simulations, system studies for the spent fuel transmuter, based on heavy metal coolant and advanced nuclear fuel, contribution to the spallation target design being manufactured in IPPE, Obninsk, and accelerator reliability studies. Moreover a lot of efforts were put to further develop existing international collaboration with the most active research groups in the world together with educational activities in Sweden including a number of meetings and workshops and a graduate course in transmutation. This project has been conducted in close collaboration with the EU-project `Impact of the accelerator based technologies on nuclear fission safety` - IABAT and in bilateral cooperation with different foreign research groups 31 refs, 23 figs

  7. System and safety studies of accelerator driven transmutation systems. Annual report 1998

    This annual report describes the accelerator-driven transmutation project conducted at the Department of Nuclear and Reactor Physics at the Royal Institute of Technology. The main results are: development of the simulation tools for accelerator-driven transmutation calculations including an integrated Monte-Carlo burnup module and improvements of neutron energy fission yield simulations, processing of the evacuated nuclear data files including preparation of the temperature dependent neutron cross-sections, development of nuclear data for a medium energy range for some isotopes, development of the models and codes for radiation damage simulations, system studies for the spent fuel transmuter, based on heavy metal coolant and advanced nuclear fuel, contribution to the spallation target design being manufactured in IPPE, Obninsk, and accelerator reliability studies. Moreover a lot of efforts were put to further develop existing international collaboration with the most active research groups in the world together with educational activities in Sweden including a number of meetings and workshops and a graduate course in transmutation. This project has been conducted in close collaboration with the EU-project 'Impact of the accelerator based technologies on nuclear fission safety' - IABAT and in bilateral cooperation with different foreign research groups

  8. 3 MV hypervelocity dust accelerator at the Colorado Center for Lunar Dust and Atmospheric Studies

    A hypervelocity dust accelerator for studying micrometeorite impacts has been constructed at the Colorado Center for Lunar Dust and Atmospheric Studies (CCLDAS) at the University of Colorado. Based on the Max-Planck-Institüt für Kernphysik (MPI-K) accelerator, this accelerator is capable of emitting single particles of a specific mass and velocity selected by the user. The accelerator consists of a 3 MV Pelletron generator with a dust source, four image charge pickup detectors, and two interchangeable target chambers: a large high-vacuum test bed and an ultra-high vacuum impact study chamber. The large test bed is a 1.2 m diameter, 1.5 m long cylindrical vacuum chamber capable of pressures as low as 10−7 torr while the ultra-high vacuum chamber is a 0.75 m diameter, 1.1 m long chamber capable of pressures as low as 10−10 torr. Using iron dust of up to 2 microns in diameter, final velocities have been measured up to 52 km/s. The spread of the dust particles and the effect of electrostatic focusing have been measured using a long exposure CCD and a quartz target. Furthermore, a new technique of particle selection is being developed using real time digital filtering techniques. Signals are digitized and then cross-correlated with a shaped filter, resulting in a suppressed noise floor. Improvements over the MPI-K design, which include a higher operating voltage and digital filtering for detection, increase the available parameter space of dust emitted by the accelerator. The CCLDAS dust facility is a user facility open to the scientific community to assist with instrument calibrations and experiments.

  9. Accelerator research studies. Technical progress report, June 1, 1992--May 31, 1993

    1993-03-01

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy under grant number DE-FG05-91ER40642, is currently in the second year of a three-year funding cycle. The program consists of the following three tasks: TASK A, ``Study of Transport and Longitudinal Compression of Intense, High-Brightness Beams,`` (P.I., M. Reiser); TASK B, ``Study of Collective Ion Acceleration by Intense Electron Beams and Pseudospark Produced High Brightness Electron Beams,`` (Co-P.I.`s, W.W. Destler, M. Reiser, M.J. Rhee, and C.D. Striffler); TASK C, ``Study of a Gyroklystron High-Power Microwave Source for Linear Colliders,`` (Co-P.I.`s, V.L. Granatstein, W. Lawson, M. Reiser, and C.D. Striffler). In this report we document the progress that has been made during the past year for each of the three tasks.

  10. Study on determination of stress level by seismic stress drops and the stress axis deflections before and after large earthquakes

    WAN Yong-ge

    2006-01-01

    To obtain the stress level at the earthquake source, this paper sets forth the solution of the stress magnitude at the earthquake source by seismic stress drop and the stress axis deflections before and after large earthquakes. The pre-seismic and post-seismic stress direction can be statistically determined by a large collection of foreshock and aftershock focal mechanism data while the stress drop can be determined through the source fracture inversion from seismic wave data or crust deformation data. The paper attempts to make a fundamental contribution to seismic dynamics.

  11. The Dust Accelerator Facility of the Colorado Center for Lunar Dust and Atmospheric Studies

    The NASA Lunar Institute's Colorado Center for Lunar Dust and Atmospheric Studies has recently completed the construction of a new experimental facility to study hypervelocity dust impacts. The installation includes a 3 MV Pelletron, accelerating small particles in the size range of 0.1 to few microns to velocities in the range of 1 to 100 km/s. Here we report the capabilities of our facility, and the results of our first experiments.

  12. An accelerator-based neutron microbeam system for studies of radiation effects

    Xu, Yanping; Randers-Pehrson, Gerhard; Marino, Stephen A.; Bigelow, Alan W.; Akselrod, Mark S.; Sykora, Jeff G.; Brenner, David J.

    2010-01-01

    A novel neutron microbeam is being developed at the Radiological Research Accelerator Facility (RARAF) of Columbia University. The RARAF microbeam facility has been used for studies of radiation bystander effects in mammalian cells for many years. Now a prototype neutron microbeam is being developed that can be used for bystander effect studies. The neutron microbeam design here is based on the existing charged particle microbeam technology at the RARAF. The principle of the neutron microbeam...

  13. Stress

    Keller, Hanne Dauer

    2015-01-01

    Kapitlet handler om stress som følelse, og det trækker primært på de få kvalitative undersøgelser, der er lavet af stressforløb.......Kapitlet handler om stress som følelse, og det trækker primært på de få kvalitative undersøgelser, der er lavet af stressforløb....

  14. A Study on Effect of Local Wall Thinning in Carbon Steel Elbow Pipe on Elastic Stress Concentration

    Feeder pipes that connect the inlet and outlet headers to the reactor core in CANDU nuclear power plants are considered as safety Class 1 piping items. Therefore, fatigue of feeder pipes should be assessed at design stage in order to verify structural integrity during design lifetime. In accordance with the fatigue assessment result, cumulative usage factors of some feeder pipes have significant values. The feeder pipes made of SA-106 Grade B or C carbon steel have some elbows and bends. An active degradation mechanism for the carbon steel outlet feeder piping is local wall thinning due to flow-accelerated corrosion. Inspection results from plants and metallurgical examinations of removed feeders indicated the presence of localized thinning in the vicinity of the welds in the lower portion of outlet feeders, such as Grayloc hub-to-bend weld, Grayloc hub-to-elbow weld, elbow-to-elbow, and elbow-to-pipe weld. This local wall thinning can cause increase of peak stress due to stress concentration by notch effect. The increase of peak stress results in increase of cumulative usage factor. However, present fatigue assessment doesn't consider the stress concentration due to local wall-thinning. Therefore, it is necessary to assess the effect of local wall thinning on stress concentration. This study investigates the effect of local wall thinning geometry on stress concentration by performing finite element elastic stress analysis

  15. Longitudinal Study on Reciprocity between Personality Traits and Parenting Stress

    Rantanen, Johanna; Tillemann, Kati; Metsäpelto, Riitta-Leena; Kokko, Katja; Pulkkinen, Lea

    2015-01-01

    Reciprocal associations between the Big Five personality traits and parenting stress--including both parents' feelings of their distress and perception of their incompetence as parents--were studied with 248 participants (49% of which were males). Longitudinal data, collected at ages 33/36, 42 and 50 years, were used. Cross-lagged path…

  16. Stress and parental competence: a study with working parents

    Pérez Padilla, Javier

    2010-06-01

    Full Text Available The aim of this study is to explore the role of some dimensions related with labor and family context, and examine their influence to the stress level associated with parenthood. Special attention was given to the perceived competence as a parent after controlling different characteristics from both contexts. Several analyses were performed with the information obtained from 74 active-working parents responsible for at least one school-aged child. The results indicated that the work time, the number of children at home and the perception of difficulty about child caring were the most important variables for explaining the parental stress. Furthermore, analysis showed that a positive and optimistic perception of the parental role and child care helped to mitigate the appearance of parental stress

  17. Establishment of nuclear data system - Feasibility study for neutron-beam= facility at pohang accelerator laboratory

    Nam Kung, Won; Koh, In Soo; Cho, Moo Hyun; Kim, Kui Nyun; Kwang, Hung Sik; Park, Sung Joo [Pohang Accelerator Laboratory, Pohang (Korea, Republic of)

    1996-12-01

    Nuclear data which have been produced by a few developed countries in the= past are essential elements to many disciplines, especially to nuclear engineering. As we promote our nuclear industry further to the level of advanced countries, we also have to establish the Nuclear Data System to produce and evaluate nuclear data independently. We have studied the possibility to build a neutron-beam facility utilizing accelerator facilities, technologies and man powers at pohang Accelerator Laboratory. We found specific parameters for the PAL 100-MeV electron linac based on the existing klystron, modulator, accelerating tubes and other facilities in the PAL; the beam energy is 60-100 MeV, the beam current for the short pulse (10 ns) is 2 A and for the long pulse is 500 mA and the pulse repetition rate is 60 Hz. We propose a neutron-beam facility using PAL 100-MeV electron linac where we can use a Ta-target for the neutron generation and three different time-of-flight beam lines (10 m, 20 m, and 100 m). One may find that the proposed neutron-beam facility is comparable with other operating neutron facilities in the world. We conclude that the proposed neutron-beam facility utilizing the existing accelerator facility in the PAL would be an excellent facility for neutron data production in combination with the ` Hanaro` facility in KAERI. 8 refs., 11 tabs., 12 figs. (author)

  18. Review of heavy-ion induced desorption studies for particle accelerators

    Mahner, Edgar

    2008-10-01

    During high-intensity heavy-ion operation of several particle accelerators worldwide, large dynamic pressure rises of orders of magnitude were caused by lost beam ions that impacted under grazing angle onto the vacuum chamber walls. This ion-induced desorption, observed, for example, at CERN, GSI, and BNL, can seriously limit the ion intensity, luminosity, and beam lifetime of the accelerator. For the heavy-ion program at CERN’s Large Hadron Collider collisions between beams of fully stripped lead (Pb82+208) ions with a beam energy of 2.76TeV/u and a nominal luminosity of 1027cm-2s-1 are foreseen. The GSI future project FAIR (Facility for Antiproton and Ion Research) aims at a beam intensity of 1012 uranium (U28+238) ions per second to be extracted from the synchrotron SIS18. Over the past years an experimental effort has been made to study the observed dynamic vacuum degradations, which are important to understand and overcome for present and future particle accelerators. The paper reviews the results obtained in several laboratories using dedicated test setups, the mitigation techniques found, and their implementation in accelerators.

  19. Simulation studies of acceleration of heavy ions and their elemental compositions

    By using a one-dimensional, electromagnetic particle simulation code with full ion and electron dynamics, we have studied the acceleration of heavy ions by a nonlinear magnetosonic wave in a multi-ion-species plasma. First, we describe the mechanism of heavy ion acceleration by magnetosonic waves. We then investigate this by particle simulations. The simulation plasma contains four ion species: H, He, O, and Fe. The number density of He is taken to be 10% of that of H, and those of O and Fe are much lower. Simulations confirm that, as in a single-ion-species plasma, some of the hydrogens can be accelerated by the longitudinal electric field formed in the wave. Furthermore, they show that magnetosonic waves can accelerate all the particles of all the heavy species (He, O, and Fe) by a different mechanism, i.e., by the transverse electric field. The maximum speeds of the heavy species are about the same, of the order of the wave propagation speed. These are in good agreement with theoretical prediction. These results indicate that, if high-energy ions are produced in the solar corona through these mechanisms, the elemental compositions of these heavy ions can be similar to that of the background plasma, i.e., the corona

  20. A STUDY OF ACADEMIC STRESS AND GENDER DIFFERENCE

    Bhosale U. V.

    2014-01-01

    The present research statement of the problem was “AStudy of Academic Stress and Gender Difference.” The main objectives were to examine the academic frustration, academic conflict, academic pressure and academic anxiety among boys and girls. This study was completed on secondary school students in 10th standard. The one hundred fifty students were selected for the study. The purposive sampling method was used for the selection of the sample. The study student's gender was ind...

  1. Study of stress, self-esteem and depression in medical students and effect of music on perceived stress.

    Baste, Vrushali S; Gadkari, Jayashree V

    2014-01-01

    Medical students are exposed to many stressors and if stress is perceived negatively or becomes excessive can affect academic performance and health adversely. The objective of this study was to assess stress, predominant stressor and effect of music on perceived stress. 90 undergraduate students were selected randomly. A written questionnaire about personal information, stressful factors, ways to cope up stress, Rosenberg self-esteem scale (Rosenberg, 1965) and 'Quick Inventory of Depressive Symptomatology' self-rated 16 (QIDS-SR-16) was given.45.6% Students had mild stress, 7.7% students had moderate stress and 1.1% students had severe stress. Academic factors were the predominant cause of stress in most students, followed by physical, social and emotional. On Rosenberg self-esteem scale (Rosenberg, 1965) 85.6% students had high self-esteem and on QIDS-SR16 50% students had depression. Effect of music on perceived stress was statistically significant. Medical curriculum is associated with increased stress in students. Music can be used as simple, inexpensive and effective therapy for stress. PMID:25906616

  2. Reactor-accelerator coupled experiments (RACE): A feasibility study at TAMU

    A series of accelerator driven system (ADS) experiments are being planned to conduct demonstration and benchmark studies involving a nuclear reactor in a subcritical condition coupled to an accelerator driven neutron source. These experiments are being planned to use various levels of criticality and various power levels allowing for kinetics evaluation with and without temperature feedback. The reactor fuel to be used in these experiments is TRIGA reactor fuel. These reactor fuels are inherently safe and the reactor systems involved have large coolant capacities to ensure safe operation. The cores to be considered will be fully-instrumented and will allow for detailed and accurate data on core power levels, temperatures, and neutron fluxes during the experiments. A feasibility study is currently in progress at Texas A and M Univ. (TAMU) to determine the viability and capability of these experiments. Preliminary results of this feasibility study are given. (authors)

  3. Police department personnel stress resilience training: an institutional case study.

    Weltman, Gershon; Lamon, Jonathan; Freedy, Elan; Chartrand, Donald

    2014-03-01

    The objective of this case study was to test the impact in law enforcement personnel of an innovative self-regulation and resilience building program delivered via an iPad (Apple Inc, Cupertino, California) app and personal mentoring. The Stress Resilience Training System (SRTS) app includes training on stress and its effects, HRV coherence biofeedback, a series of HeartMath self-regulation techniques (The Institute of HeartMath, Boulder Creek, California), and HRV-controlled games. The stressful nature of law enforcement work is well established, and the need for meaningful and effective stress resilience training programs is becoming better understood, as it has been in the military. Law enforcement and military service share many stress-related features including psychological stressors connected with the mission, extended duty cycles, and exposure to horrific scenes of death and injury. San Diego (California) Police Department personnel who participated in the study were 12 sworn officers and 2 dispatchers, 10 men and 4 women. The SRTS intervention comprised an introductory 2-hour training session, 6 weeks of individualized learning and practice with the SRTS app, and four 1-hour telephone mentoring sessions by experienced HeartMath mentors spread over a four week period. Outcome measures were the Personal and Organizational Quality Assessment (POQA) survey, the mentors' reports of their observations, and records of participants' comments from the mentoring sessions. The POQA results were overwhelmingly positive: All four main scales showed improvement; Emotional Vitality improved by 25% (P=.05) and Physical Stress improved by 24% (P=.01). Eight of the nine subscales showed improvement, with the Stress subscale, perhaps the key measure of the study, improving by approximately 40% (P=.06). Participant responses were also uniformly positive and enthusiastic. Individual participants praised the program and related improvements in both on-the-job performance and

  4. Laser Wakefield Acceleration: Structural and Dynamic Studies. Final Technical Report ER40954

    Downer, Michael

    2014-12-19

    Particle accelerators enable scientists to study the fundamental structure of the universe, but have become the largest and most expensive of scientific instruments. In this project, we advanced the science and technology of laser-plasma accelerators, which are thousands of times smaller and less expensive than their conventional counterparts. In a laser-plasma accelerator, a powerful laser pulse exerts light pressure on an ionized gas, or plasma, thereby driving an electron density wave, which resembles the wake behind a boat. Electrostatic fields within this plasma wake reach tens of billions of volts per meter, fields far stronger than ordinary non-plasma matter (such as the matter that a conventional accelerator is made of) can withstand. Under the right conditions, stray electrons from the surrounding plasma become trapped within these “wake-fields”, surf them, and acquire energy much faster than is possible in a conventional accelerator. Laser-plasma accelerators thus might herald a new generation of compact, low-cost accelerators for future particle physics, x-ray and medical research. In this project, we made two major advances in the science of laser-plasma accelerators. The first of these was to accelerate electrons beyond 1 gigaelectronvolt (1 GeV) for the first time. In experimental results reported in Nature Communications in 2013, about 1 billion electrons were captured from a tenuous plasma (about 1/100 of atmosphere density) and accelerated to 2 GeV within about one inch, while maintaining less than 5% energy spread, and spreading out less than ½ milliradian (i.e. ½ millimeter per meter of travel). Low energy spread and high beam collimation are important for applications of accelerators as coherent x-ray sources or particle colliders. This advance was made possible by exploiting unique properties of the Texas Petawatt Laser, a powerful laser at the University of Texas at Austin that produces pulses of 150 femtoseconds (1 femtosecond is 10

  5. The rise of accelerated energy innovation and its implications for sustainable innovation studies:a UK perspective

    Winskel, Mark; Radcliffe, Jonathan

    2014-01-01

    Accelerated energy innovation’ has become a prominent aspect of energypolicymaking in response to more urgent drivers for change. This paper charts the rise of accelerated energy innovation in the UK, and considers its possible implications for sustainable innovation studies and research-policy exchange. As manifest in the UK, accelerated energy innovation has a number of distinctive features: an emphasis on relatively short term dynamics (years rather than decades), a focus on cost reductio...

  6. Study of occupational stress among railway engine pilots

    Devesh Kumar

    2011-01-01

    Full Text Available Background: Traffic volume and speed is going to be increased in Indian Railways successively, leading to higher stress in staff connected with train operations. The jobs of railway engine pilots come under the category of high-strain jobs, necessitating a need to conduct multicentric study to unfold the factors associated with occupational stress and organizational strategies. Materials and Methods: Present study covered 185 railway engine pilots and office clerks working in various railway zones by incidental method. Occupational Stress Index (OSI test developed by Srivastva and Singh, questionnaire of specific stressors constructed by authors and laboratory test battery for psychological screening of high-speed train pilots were used as tools. Results: Means of OSI and all the 12 occupational stressors of railway engine pilots were found significantly higher to that of office clerks. Means of OSI and occupational stressors of goods train pilots were significantly higher in comparison to high-speed train pilots and passenger train pilots. Study revealed positive correlation of speed perception and complex reaction time tests and negative correlation of other constituent tests of laboratory test battery to OSI test. Highest subgroup of stressor observedwas role overload followed by role conflict. Conclusions: These findings provide a prima facie evidence of higher occupational stress among railway engine pilots because of identified specific stressors prevalent in their job and explore the possible intervention strategies for its reduction. Significant correlation is noticed between OSI and laboratory test results, indicating its relevant utility in preliminary psychological screening.

  7. Design studies and commissioning plans for plasma acceleration research station experimental program

    Mete, O.; Xia, G.; Hanahoe, K. [School of Physics and Astronomy, The University of Manchester, Manchester M13 9PL (United Kingdom); The Cockcroft Institute, Sci-Tech Daresbury, Warrington, Halton WA4 4AD (United Kingdom); Dover, M.; Wigram, M.; Wright, J.; Zhang, J. [School of Physics and Astronomy, The University of Manchester, Manchester M13 9PL (United Kingdom); Smith, J. [Tech-X UK Ltd, Sci-Tech Daresbury, Warrington, Cheshire WA4 4FS (United Kingdom)

    2015-10-15

    Plasma acceleration research station is an electron beam driven plasma wakefield acceleration test stand proposed for CLARA facility in Daresbury Laboratory. In this paper, the interaction between the electron beam and the plasma is numerically characterised via 2D numerical studies by using VSIM code. The wakefields induced by a single bunch travelling through the plasma were found to vary from 200 MV/m to 3 GV/m for a range of bunch length, bunch radius, and plasma densities. Energy gain for the particles populating the bunch tail through the wakefields driven by the head of the bunch was demonstrated. After determining the achievable field for various beams and plasma configurations, a reference setting was determined for further studies. Considering this reference setting, the beam quality studies were performed for a two-bunch acceleration case. The maximum energy gain as well as the energy spread mitigation by benefiting from the beam loading was investigated by positioning the witness and driver bunches with respect to each other. Emittance growth mechanisms were studied considering the beam-plasma and beam-wakefield interactions. Eventually, regarding the findings, the initial commissioning plans and the aims for the later stages were summarised.

  8. Design studies and commissioning plans for plasma acceleration research station experimental program

    Plasma acceleration research station is an electron beam driven plasma wakefield acceleration test stand proposed for CLARA facility in Daresbury Laboratory. In this paper, the interaction between the electron beam and the plasma is numerically characterised via 2D numerical studies by using VSIM code. The wakefields induced by a single bunch travelling through the plasma were found to vary from 200 MV/m to 3 GV/m for a range of bunch length, bunch radius, and plasma densities. Energy gain for the particles populating the bunch tail through the wakefields driven by the head of the bunch was demonstrated. After determining the achievable field for various beams and plasma configurations, a reference setting was determined for further studies. Considering this reference setting, the beam quality studies were performed for a two-bunch acceleration case. The maximum energy gain as well as the energy spread mitigation by benefiting from the beam loading was investigated by positioning the witness and driver bunches with respect to each other. Emittance growth mechanisms were studied considering the beam-plasma and beam-wakefield interactions. Eventually, regarding the findings, the initial commissioning plans and the aims for the later stages were summarised

  9. Experimental study of ion beam optics in a two-stage accelerator

    Hydrogen ion beam optics in a two-stage linear acceleration system is studied by examining the beam divergence as a function of the voltage and gap distribution, the beam perveance, the background gas pressure, the aspect ratio, and the total accelerating energy (60-110 keV). The system consists of four electrodes with single, cylindrical, straight-bore apertures acting as an extraction-accel--decel column. An optimum relation between the field ratio and the extraction perveance is obtained from measurements for the minimum beam divergence condition. The HWHM divergence angle is 0 under optimum conditions. Qualitative agreement between the measurements and a previous theoretical study is noticed. A potential application of the results to high energy neutral beam injectors for fusion research is also discussed

  10. Contribution to the study of standing wave bi-periodical accelerating structures for electrons

    Experimental results on bi-periodic standing wave accelerating structures are presented. These structures which are characterized by a high effective shunt impedance, are designed for standing wave, high duty cycle electron accelerators. Two types of structures are studied: the on-axis coupled structure and the coaxial coupled structure. The expressions for the dispersion relation, coupling coefficients, phase and group velocity are derived from a coupled resonator model. An experimental method to eliminate the stop-band is put forward. The influence of the coupling slots on the dispersion curves is studied experimentally. The effective shunt impedance and the transit time factor are measured by the field perturbation techniques. Measured parameters are compared with SUPERFISH theoretical calculations. The field perturbation technique is also applied to measure the transverse shunt impedance of the dipole modes which are responsible for the beam breakup phenomenon. (author)

  11. Early Acceleration of Mathematics Students and its Effect on Growth in Self-esteem: A Longitudinal Study

    Ma, Xin

    2002-11-01

    The Longitudinal Study of American Youth (LSAY) database was employed to examine the educational practice of early acceleration of students of mathematics on the development of their self-esteem across the entire secondary grade levels. Students were classified into three different academic categories (gifted, honors, and regular). Results indicated that, in terms of the development of their self-esteem, gifted students benefited from early acceleration, honors students neither benefited nor were harmed by early acceleration, and regular students were harmed by early acceleration. Early acceleration in mathematics promoted significant growth in self-esteem among gifted male students and among gifted, honors, and regular minority students. When students were accelerated, schools showed similar average growth in self-esteem among gifted students and regular students and a large effect of general support for mathematics on the average growth in self-esteem among honors students.

  12. Anticipatory processes under academic stress: an ERP study.

    Duan, Hongxia; Yuan, Yiran; Yang, Can; Zhang, Liang; Zhang, Kan; Wu, Jianhui

    2015-03-01

    It is well known that preparing for and taking high-stakes exams has a significant influence on the emotional and physiological wellbeing of exam-takers, but few studies have investigated the resulting cognitive changes. The current study examined the effect of examination-induced academic stress on anticipation in information processing. Anticipation was indexed using the contingent negative variation (CNV). Electroencephalograms (EEG) were collected from 42 participants using the classic S1-S2 paradigm. These participants were preparing for the Chinese National Postgraduate Entrance Exam (NPEE). EEGs were also collected from 21 age-matched, non-exam comparison participants. The levels of perceived stress and state anxiety were higher and both the initial CNV (iCNV) and the late CNV (lCNV) were more negative in the exam group than in the non-exam group. These results suggest that participants under academic stress experienced greater anticipation of upcoming events. More important, for the non-exam group, state anxiety was positively related to both the iCNV and lCNV amplitude, and this correlation existed when trait anxiety was controlled; however, there was no such relationship in the exam group. These results suggested that the cortical anticipatory activity in the high-stressed exam group reached the maximum ceiling, leaving little room for transient increases in state anxiety. PMID:25659936

  13. Study of a spoke-type superconducting cavity for high power proton accelerators

    Since a few years, a lot of projects (especially dedicated to transmutation, radioactive beams production, spallation neutron sources or neutrinos factories) are based on high power proton linear accelerators. It has been demonstrated, thanks to their excellent RF performances, that superconducting elliptical cavities represent the best technological solution for the high energy part of these linacs (proton energy from typically 100 MeV). On the contrary, between 5 and 100 MeV, nothing is clearly settled and intensive studies on low-beta cavities are under progress. The main objective of this thesis is the study of a new low-beta cavity, called 'spoke', which could be used in the low energy part of European XADS (experimental accelerator driven system) and EURISOL (European isotope separation on-line) accelerators projects. A complete study of a beta 0.35 spoke cavity has been done: from its electromagnetic and mechanical optimization to warm and, above all, cold experimental tests: an accelerating field of 12.2 MV/m has been reached at T=4.2 K, that is to say one of the best value among the spoke cavities performances in the world. It has been shown that the specific ratio of a third, between the spoke bar diameter and the cavity length, led to optimize the surface electromagnetic fields. Moreover, spoke cavities can be used without any trouble, in the low energy part, due to their good rigidity. The experimental measurements performed on the cavity have confirmed the theoretical calculations, especially, concerning the expected frequency and mechanical behavior. Another study, performed on elliptical cavities, gave an explanation of the discrepancies between the measured and calculated frequencies thanks to a precise 3-dimensional geometrical control. (author)

  14. LANL sunnyside experiment: Study of neutron production in accelerator-driven targets

    Measurements have been made of the neutron production in prototypic targets for accelerator driven systems. Studies were conducted on four target assemblies containing lead, lithium, tungsten, and a thorium-salt mixture. Integral data on total neutron production were obtained as well as more differential data on neutron leakage and neutron flux profiles in the blanket/moderator region. Data analysis on total neutron production is complete and shows excellent agreement with calculations using the LAHET/MCNP code system

  15. Study of relativistic magnetron with supply from heavy-current linear induction accelerators

    The physical processes in the system of the SHF-frequency relativistic generator-power supply characterized by the strong feedback are studied. The computerized model for calculating the output parameters is similar systems represented by the equivalent schemes is developed. The concrete realization of the model is considered by the example of the linear induction accelerator on the magnetic elements, intended for the relativistic magnetron operation, the nonlinear equivalent schemes whereof are determined in accordance with the averaged motion theory

  16. Accelerator research studies. Final report, June 1, 1994--May 31, 1995

    NONE

    1995-08-01

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy has completed the third year of its three-year funding cycle and an additional one-year, no-cost extension. The program consisted of the following three tasks: Task A -- Study of the transport and longitudinal compression of intense, high-brightness beams; Task B -- Study of high-brightness beam generation in pseudospark devices; Task C -- Study of a gyroklystron high-power microwave source for linear colliders. The research carried out for each task and progress made is reported.

  17. Accelerator research studies. Final report, June 1, 1991--May 31, 1994

    NONE

    1994-12-31

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy is currently in the third year of its three-year funding cycle. The program consists of the following three tasks: Task A -- Study of the transport and longitudinal compression of intense, high-brightness beams; Task B -- Study of high-brightness beam generation in pseudospark devices; Task C -- Study of a gyroklystron high-power microwave source for linear colliders. The research for each task is detailed in this report.

  18. Accelerator research studies. Final report, June 1, 1991 - May 31, 1994

    The Accelerator Research Studies program at the University of Maryland, sponsored by the Department of Energy is currently in the third year of its three-year funding cycle. The program consists of the following three tasks: Task A -- Study of the transport and longitudinal compression of intense, high-brightness beams; Task B -- Study of high-brightness beam generation in pseudospark devices; Task C -- Study of a gyroklystron high-power microwave source for linear colliders. The research for each task is detailed in this report

  19. Accelerator-based conversion (ABC) of weapons plutonium: Plant layout study and related design issues

    In preparation for and in support of a detailed R and D Plan for the Accelerator-Based Conversion (ABC) of weapons plutonium, an ABC Plant Layout Study was conducted at the level of a pre-conceptual engineering design. The plant layout is based on an adaptation of the Molten-Salt Breeder Reactor (MSBR) detailed conceptual design that was completed in the early 1070s. Although the ABC Plant Layout Study included the Accelerator Equipment as an essential element, the engineering assessment focused primarily on the Target; Primary System (blanket and all systems containing plutonium-bearing fuel salt); the Heat-Removal System (secondary-coolant-salt and supercritical-steam systems); Chemical Processing; Operation and Maintenance; Containment and Safety; and Instrumentation and Control systems. Although constrained primarily to a reflection of an accelerator-driven (subcritical) variant of MSBR system, unique features and added flexibilities of the ABC suggest improved or alternative approaches to each of the above-listed subsystems; these, along with the key technical issues in need of resolution through a detailed R ampersand D plan for ABC are described on the bases of the ''strawman'' or ''point-of-departure'' plant layout that resulted from this study

  20. Study of stress in nuclear area workers: silent enemy

    Martins, Maria da Penha Sanches; Vanni, Silvia Regina [Centro Tecnologico da Marinha (CTMSP-SP), SP (Brazil); Andrade, Delvonei Alves de; Sabundjian, Gaiane, E-mail: delvonei@ipen.b, E-mail: gdjian@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The nuclear accidents occurred in Three Mile Island, Chernobyl and Fukushima were influenced by human factors. The objective of this paper is to study about the factors that influence the level of stress of the nuclear area workers. The paper is based on theoretical assumptions on occupational stress and its manifestations. The methodology used is based on questionnaires and interviews, obtained from Martins' work published in 2008 about the study of human factors focused on research reactor operators IEA-R1, of the Instituto de Pesquisas Energeticas e Nucleares (IPEN). In that study were analyzed the accidents occurred by human failure. The results presented in this paper showed some improvements in the reactors operators' work, and health. Operational reliability and facilities safety also improved. (author)

  1. Study of stress in nuclear area workers: silent enemy

    The nuclear accidents occurred in Three Mile Island, Chernobyl and Fukushima were influenced by human factors. The objective of this paper is to study about the factors that influence the level of stress of the nuclear area workers. The paper is based on theoretical assumptions on occupational stress and its manifestations. The methodology used is based on questionnaires and interviews, obtained from Martins' work published in 2008 about the study of human factors focused on research reactor operators IEA-R1, of the Instituto de Pesquisas Energeticas e Nucleares (IPEN). In that study were analyzed the accidents occurred by human failure. The results presented in this paper showed some improvements in the reactors operators' work, and health. Operational reliability and facilities safety also improved. (author)

  2. Design study of 500 keV H- accelerator for ITER NB system

    In the neutral beam (NB) system for heating and current drive of ITER, detailed designs of a five stage Multi Aperture and Multi Grid (MAMuG) accelerator to produce 1 MeV 40 A D- and 870 keV 46 A H- ion beams are ongoing. However, it was expected that shinethrough power from the 870 keV H0 beam was above tolerable level for the maximum plasma density prior to any H mode. Therefore, it was required to reduce the beam energy to 500 keV with maintaining high beam current. The objective of this study is to identify necessary modifications from the original five stage accelerator to a three stage accelerator to produce 500 keV H- ion beam through the physics design based on a beam optics, a beamlet steering and a stripping loss of negative ions. In the beam optics study utilizing a 2D beam analysis code, necessary modifications in aperture diameter, grid thickness and grid spacing were proposed. In a 3D multi beamlets analysis, aperture offsets in the ESG (Electron Suppression Grid) to compensate beamlet deflections and another aperture offset in the GRG (GRounded Grid) to steer the beamlets to a focal point were designed. In a 3D gas flow analysis, it was confirmed that stripping loss of negative ions was not changed and gas density around the beam source satisfied a design requirement for high voltage holding in a modified accelerator configuration proposed in the beam optics study. Finally, the items for modification were summarized. (author)

  3. Prospective community study of family stress and anxiety in (pre)adolescents: the TRAILS study

    Van Oort, Floor; Verhulst, Frank; Ormel, Johan Hans; Huizink, Anja

    2009-01-01

    textabstractFor prevention of anxiety in children and adolescents, it is important to know whether family stress is a predictor of anxiety. We studied this in 1,875 adolescents from the Tracking Adolescents' Individual Lives Survey (TRAILS) who were followed up for 2 years, from age 10-12 to 12-14 years. Adolescents reported anxiety and depression symptoms at both assessments, and parents reported family stress (family dysfunction and parenting stress) at the first assessment. Family dysfunct...

  4. Study of residual stress simulation of laser welding

    In this study, simple heat source model was applied in heat transfer and residual stress analyses of laser welding. The mechanism of laser welding is too complicated for temperature distribution to be obtained. Various heat input models have been proposed to describe the laser weld profiles, thermal absorption characteristics, and temperature distributions. In the first place, we have selected one of the models, the combination of a point and a line heat sources. Despite the model's simplicity, it is able to describe a laser weld profile. Single pass laser weld joint was made with high power CO2 laser welding in order to obtain weld profiles and residual stress distributions. These data were applied to examine the results of the analyses. In the heat transfer analysis, almost the same weld profile was able to be obtained. Additionally, welding residual stress analysis was carried out based on these data. As a result, residual stress distributions near the weld metal were almost the same as measured ones. (author)

  5. Stress corrosion studies in solvent refined coal liquefaction pilot plants

    Baylor, V.B.; Keiser, J.R.; Allen, M.D.; Lawrence, E.J.

    1980-12-01

    Coal liquefaction plants with 6000 ton/d capacity are currently being planned by DOE as a step toward commercial production of synthetic fossil fuels. These plants will demonstrate the large-scale viability of the Solvent Refined Coal (SRC) process, which has been used since 1974 in two operating pilot plants: a 50-ton/d unit at Fort Lewis, Washington, and a 6-ton/d plant in Wilsonville, Alabama. Experience in these plants has shown that austenitic stainless steels are susceptible to stress corrosion cracking associated with residual stresses from cold working or welding. The corrodents responsible for the cracking have not yet been positively identified but are suspected to include polythionic acids and chlorides. To screen candidate materials of construction for resistance to stress corrosion cracking, racks of stressed U-bend specimens in welded and as-wrought conditions have been exposed at the Wilsonville and Fort Lewis SRC pilot plants. These studies have identified alloys that are suitable for critical plant applications.

  6. Stress-corrosion cracking studies in coal-liquefaction systems

    Baylor, V.B.; Keiser, J.R.

    1981-01-01

    Coal liquefaction plants with 6000 ton/d capacity are currently being planned by DOE as a step toward commercial production of synthetic fossil fuels. These plants will demonstrate the large-scale viability of the Solvent Refined Coal (SRC) process, which has been used since 1974 in two operating pilot plants: a 50-ton/d unit at Fort Lewis, Washington, and a 6-ton/d plant in Wilsonville, Alabama. Experience in these plants has shown that austenitic stainless steels are susceptible to stress corrosion cracking associated with residual stresses from cold working or welding. The corrodants responsible for the cracking have not yet been positively identified but are suspected to include polythionic acids and chlorides. To screen candidate materials of construction for resistance to stress corrosion cracking, racks of stressed U-bend specimens in welded and as-wrought conditions have been exposed at the Wilsonville and Fort Lewis SRC pilot plants. These studies have identified alloys that are suitable for critical plant applications.

  7. The stress systems in depression: a postmortem study

    Ai-Min Bao

    2014-12-01

    Full Text Available After trauma, depressive disorders are among the most frequent emerging diagnoses. However, although the symptoms of depression are well characterized, the molecular mechanisms underlying this disorder are largely unknown. Factors involved in the heterogeneous pathogenesis of depression include polymorphisms in stress-related genes, gender, age, developmental history, and environmental (traumatic stressors such as epigenetic factors. These factors may make different parts of the stress-related brain systems more vulnerable to different stressful or traumatic life events or psychological stresses, causing alterations in a network of neurotransmitters and neuromodulators including amines, amino acids, nitric oxide (NO, and neuropeptides, and finally make individuals at risk for depression. The hypothalamo–pituitary–adrenal (HPA axis has a prominent position in this network. With the postmortem brain material obtained from the Netherlands Brain Bank, we have carried on a series of studies with the aim to elucidate the specific changes in these systems in relation to special subtypes of depression. Our final destination is to set up tailor-made treatment for depressive patients on the basis of his/her developmental history, genetic and epigenetic background, and the vulnerability in particular neurobiological systems. This presentation is a review of our findings of changes in systems of sex steroids, receptors in the hypothalamic paraventricular nucleus, corticotrophin-releasing hormone, orexin, γ-aminobutyric acid, and NO in the etiology of depression, in relation to HPA activity, sex differences, and suicide.

  8. Stress level in Finemet materials studied by impedanciometry

    Carara, Marcos; Baibich, M. N.; Sommer, R. L.

    2002-05-01

    In this work, a study of the stress relief in Finemet ribbons, Fe73.5Cu1Nb3Si16.5B6, as a function of the annealing temperature is presented. The as melt-spun samples are amorphous and become partially crystallized after annealing at appropriate temperatures. For temperatures TA⩾480 °C the samples are nanocrystalline, with a microstructure composed by α-Fe1-xSix (x˜0.2) crystallites (10 nm average diameter) embedded in an amorphous matrix. Nanocrystallization, associated with stress relief effects, improves the soft magnetic properties of this kind of material. The stress level was quantified using magnetorestriction (measured by SAMR), magnetoelastic anisotropy, and domain wall energy data obtained from impedance spectra measurements. A reduction of the internal stress from 15 to 0.2 MPa was verified when comparing the as-cast to the sample annealed at 580 °C. Improvement of the magnetic softness of the samples was also followed by the increase of the domain wall and magnetization rotation contributions to the overall effective permeability.

  9. System and safety studies of accelerator driven transmutation systems. Annual report 1999

    In 1996, SKB commenced funding of the project 'System and safety studies of accelerator driven transmutation systems and development of a spallation target'. The aim of the project was stated as: Development of a complete code for simulation of transmutation processes in an accelerator driven system. Application of the code for analysis of neutron flux, transmutation rates, reactivity changes, toxicity and radiation damages in the transmutation core. Build up of competence regarding issues related to spallation targets, development of research activities regarding relevant material issues. Performing of basic experiments in order to investigate the adequacy of using the spallation. target as a neutron source for a transmutation system, and participation in the planning and implementation of an international demonstration experiment. In the present report, activities within and related to the framework of the project, performed at the department of Nuclear and Reactor Physics at the Royal Institute of Technology during 1999, are accounted for

  10. Accelerated Thermal Aging Studies on Natural Rubber in Seismic Isolation Bearings

    Most rubbers harden and eventually become brittle owing to the aging process. The thermal aging is known to be the most significant factor in the deterioration of rubber materials. The ambient temperature substantially increases the stiffness and damping of the rubber bearings, even at room temperature. Under low temperature, a long duration of exposure increases both quantities. High temperatures have a significant effect on the mechanical properties of rubber bearings. This study focuses on the aging behavior of natural rubber material used in seismic isolation bearings by accelerated heat exposure tests. Accelerated thermal aging tests were carried out for a natural rubber material, and its lifetime was predicted. The deterioration of the rubber material is more significant at high ambient temperature. In addition, the deterioration of rubber influences the adhesion between the rubber and the steel plates. Dynamic properties of the rubber will be a critical factor for defining the service time of seismic isolation bearings

  11. Study on Serum Cortisol and Perceived Stress Scale in the Police Constables

    Sanjeev S. Walvekar; Ambekar, Jeevan G.; Devaranavadagi, Basavaraj B

    2015-01-01

    Introduction: The occupational stress may be more among the police constables. Under the stressed conditions, the body secretes more Cortisol. Elevated serum cortisol levels significantly correlate with the symptoms of metabolic Syndrome. Perceived stress scale (PSS) is the most widely used psychological tool for measuring the perception of stress. The objective of this study was to examine the association between perceived stress and Serum Cortisol and also to explore stress as an occupation...

  12. Laboratory studies of lead stress corrosion of alloy 600

    Lead stress corrosion cracking of Alloy 600 was first reported in the open literature by Copson and Dean. Since then, other laboratory studies were performed and documented either in the open literature or various company reports. The Electric Power Research Institute conducted three projects to determine the possible extent of a lead stress corrosion cracking problem in nuclear power plants. The first study was a comprehensive review of the information available either in the open literature or various company reports. The second study was a water chemistry analysis program to investigate lead contamination in operating nuclear plants. The third study, a laboratory investigation, is the subject here. The primary objective of this laboratory project was to investigate the stress corrosion cracking behavior of nuclear grade Alloy 600 and Alloy 690 tubing materials in lead contaminated environments at an elevated temperature (3240C). Variables of importance included material heat treatment, lead species, specimen location (liquid or vapor), and solution pH regime. A secondary objective was to correlate any observed cracking with the test variables and calculated high temperature lead chemistries

  13. Intensity modulated radiation therapy using laser-accelerated protons: a Monte Carlo dosimetric study

    In this paper we present Monte Carlo studies of intensity modulated radiation therapy using laser-accelerated proton beams. Laser-accelerated protons coming out of a solid high-density target have broad energy and angular spectra leading to dose distributions that cannot be directly used for therapeutic applications. Through the introduction of a spectrometer-like particle selection system that delivers small pencil beams of protons with desired energy spectra it is feasible to use laser-accelerated protons for intensity modulated radiotherapy. The method presented in this paper is a three-dimensional modulation in which the proton energy spectrum and intensity of each individual beamlet are modulated to yield a homogeneous dose in both the longitudinal and lateral directions. As an evaluation of the efficacy of this method, it has been applied to two prostate cases using a variety of beam arrangements. We have performed a comparison study between intensity modulated photon plans and those for laser-accelerated protons. For identical beam arrangements and the same optimization parameters, proton plans exhibit superior coverage of the target and sparing of neighbouring critical structures. Dose-volume histogram analysis of the resulting dose distributions shows up to 50% reduction of dose to the critical structures. As the number of fields is decreased, the proton modality exhibits a better preservation of the optimization requirements on the target and critical structures. It is shown that for a two-beam arrangement (parallel-opposed) it is possible to achieve both superior target coverage with 5% dose inhomogeneity within the target and excellent sparing of surrounding tissue

  14. A computational study of dielectric photonic-crystal-based accelerator cavities

    Bauer, C. A.

    Future particle accelerator cavities may use dielectric photonic crystals to reduce harmful wakefields and increase the accelerating electric field (or gradient). Reduced wakefields are predicted based on the bandgap property of some photonic crystals (i.e. frequency-selective reflection/transmission). Larger accelerating gradients are predicted based on certain dielectrics' strong resistance to electrical breakdown. Using computation, this thesis investigated a hybrid design of a 2D sapphire photonic crystal and traditional copper conducting cavity. The goals were to test the claim of reduced wakefields and, in general, judge the effectiveness of such structures as practical accelerating cavities. In the process, we discovered the following: (1) resonant cavities in truncated photonic crystals may confine radiation weakly compared to conducting cavities (depending on the level of truncation); however, confinement can be dramatically increased through optimizations that break lattice symmetry (but retain certain rotational symmetries); (2) photonic crystal cavities do not ideally reduce wakefields; using band structure calculations, we found that wakefields are increased by flat portions of the frequency dispersion (where the waves have vanishing group velocities). A complete comparison was drawn between the proposed photonic crystal cavities and the copper cavities for the Compact Linear Collider (CLIC); CLIC is one of the candidates for a future high-energy electron-positron collider that will study in greater detail the physics learned at the Large Hadron Collider. We found that the photonic crystal cavity, when compared to the CLIC cavity: (1) can lower maximum surface magnetic fields on conductors (growing evidence suggests this limits accelerating gradients by inducing electrical breakdown); (2) shows increased transverse dipole wakefields but decreased longitudinal monopole wakefields; and (3) exhibits lower accelerating efficiencies (unless a large photonic

  15. The studies of irradiation assisted stress corrosion cracking on reactor internals stainless steel under Xe irradiation

    Wang, Rong-shan [Suzhou Nuclear Power Research Institute, Suzhou, Jiangsu Province 215004 (China); Xu, Chao-liang, E-mail: xuchaoliang@cgnpc.com.cn [Suzhou Nuclear Power Research Institute, Suzhou, Jiangsu Province 215004 (China); Liu, Xiang-bing; Huang, Ping [Suzhou Nuclear Power Research Institute, Suzhou, Jiangsu Province 215004 (China); Chen, Yu [Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Beijing 100049 (China)

    2015-02-15

    Specimens of Chinese domestic reactor internals stainless steel were irradiated with 6 MeV Xe ions for three peak displacement damage of 2, 7 and 15 dpa at room temperature. The slow strain rate tests (SSRT), grazing incidence X-ray diffraction (GIXRD) and nano-indentation tests were carried out to study the IASCC properties, phase transition and nano-hardness variations. The SSRT results indicate that the IASCC susceptibility increases with irradiation damage. Ion irradiation accelerates the stress corrosion cracking (SCC). A new ferrite phase diffraction peak of α(1 1 0) after irradiated to 7 dpa and another two α phase of α(2 0 0) and α(2 1 1) after irradiated to 15 dpa were observed by GIXRD, which may be due to localized deformation. A similar trend of irradiation hardening and IASCC susceptibility was observed, which suggests an essential connection between them.

  16. A prospective study of stress sensitivity: Emotion regulation as a moderator of the stress-depression relationship

    Michael Tooley

    2015-01-01

    According to the Diathesis-Stress Model, vulnerabilities in neurological, physiological, cognitive or affective systems predispose some people to stress sensitivity, meaning they are more likely to become depressed when they experience stress. We tested this model in a prospective study with a group of young women (aged 18 - 23). At the first session, we measured depression and three potential vulnerabilities that have been identified in the literature: EEG asymmetry in frontal activity, self...

  17. Longitudinal study on reciprocity between personality traits and parenting stress

    Rantanen, Johanna; Tillemann, Kati; Metsäpelto, Riitta-Leena; Kokko, Katja; Pulkkinen, Lea

    2014-01-01

    Reciprocal associations between the Big Five personality traits and parenting stress—including both parents’ feelings of their distress and perception of their incompetence as parents—were studied with 248 participants (49% of which were males). Longitudinal data, collected at ages 33/36, 42 and 50 years, were used. Cross-lagged path analysis revealed that in case of both mothers and fathers, neuroticism at age 33 predicted high parenting stress, and extraversion at age 33 predicted low paren...

  18. Study on Acceleration Mechanism of Liquid Alkali-free Accelerating Components%液体无碱速凝组分的速凝机理探讨

    贺雄飞; 张迅

    2014-01-01

    The acceleration mechanism of liquid alkali-free accelerating components,including aluminum sulfate and aluminum fluoride,is discussed by testing on the setting time of cement paste mixed with aluminum sulfate and aluminum fluoride respectively,as well as by XRD analysis on the cement paste mixed with accelerating components after final setting,1-day hydration and 7-day hydration.The study results show that,due to the large amount of ettringite generated and the C3 S hydration caused by calcium ion reduction and hydration heat,the setting of the cement paste is accelerated when aluminum sulfate solution is mixed into the Portland cement;due to the C3 AH6 generated,the setting of the cement paste is accelerated by aluminum fluoride solution;the aluminum ion in the aluminum fluoride solution accelerates the hydration of the cement paste;the fluoride ion in the aluminum fluoride solution retards the setting of the cement paste.The paper can provide a theoretical basis for developing and promoting the application of high-performance liquid alkali-free accelerator.%通过测试单独掺入液体无碱速凝组分硫酸铝和氟化铝后水泥浆的凝结时间以及对掺速凝组分后达到终凝、水化1d及水化7 d 的水泥浆体进行XRD图谱分析,深入探讨液体无碱速凝剂组分硫酸铝和氟化铝对水泥的速凝机理。试验结果表明:硅酸盐水泥中掺入硫酸铝溶液因生成大量的钙矾石,同时因消耗大量的钙离子及水化热的作用促进C3 S的水化作用导致浆体快速凝结;氟化铝溶液主要通过形成C3 AH6而导致水泥浆体速凝,氟化铝溶液中铝离子对水泥水化起速凝作用,而氟离子起缓凝作用。

  19. The Invasion of Coastal Areas in South China by Ipomoea cairica May Be Accelerated by the Ecotype Being More Locally Adapted to Salt Stress.

    Liu, Gang; Gao, Yang; Huang, Fang-Fang; Yuan, Ming-Yue; Peng, Shao-Lin

    2016-01-01

    Local adaptation and phenotypic plasticity are two alternative mechanisms used by invasive plants for range expansion. We conducted a series of experiments to investigate the role of these mechanisms in the recent expansion of the invasive Ipomoea cairica from non-saline to salt-stressed coastal habitats. A comparison of the plant's photosynthetic traits and construction costs across habitats was conducted through a field survey. Meanwhile, a full factorial greenhouse experiment was conducted with two ecotypes (non-saline and coastal) of I. cairica and two salinity gradients (water and 4 g L-1 NaCl solution) to evaluate the roles of the two strategies by comparing their main traits. The results revealed that the construction cost and Amax of I. cairica did not change with the habitat type. The ecotype and saline treatments, however, significantly influenced the plant growth. The non-saline ecotype (NE) generally showed higher or equal plasticity of biomass-allocation and functional traits compared to the coastal ecotype (CE). However, the fitness and biomass of the NE significantly decreased with salinity, whereas those aspects of the CE did not change. Our results indicate that the recent expansion of I. cairica into coastal areas may be accelerated by the local adaptation of the CE to salt stress. Additionally, in South China, the CE will most likely evolve adaptations to both saline and non-saline environments, which will further broaden the invasion range of I. cairica in the future. PMID:26867222

  20. Results from recent hydrogen pellet acceleration studies with a 2-m railgun

    Kim, K.; Zhang, D.J.; King, T.; Haywood, R.; Manns, W.; Venneri, F.

    1989-12-01

    A new 3.2-mm-diameter, two-stage, fuseless, plasma-arc-driven electromagnetic railgun has been designed, constructed, and successfully operated to achieve a record velocity of 2.67 km/s({sup b}) for 3.2 mmD {times} 4 mmL solid hydrogen pellet. The first stage of this hydrogen pellet injector is a combination of a hydrogen pellet generator and a gas fun. The second stage is a 2-m-long railgun which serves as a booster accelerator. The gas fun accelerates a frozen hydrogen pellet to a medium velocity and injects it into the railgun through a perforated coupling piece, which also serves a pressure-relieving mechanism. An electrical breakdown of the propellant gas, which has followed the pellet from the gas fun into the railgun, forms a conducting plasma-arc armature immediately behind the pellet allowing for fuseless operation of the railgun. Study of the pressure profile and the behavior of the plasma-arc armature inside the railgun bore led to elimination of spurious arcing, which prevents operation of the railgun at high voltages (and, therefore, at high currents). A timing circuit that can automatically measure the pellet input velocity and allows for accurate control of arc initiation behind the pellet helps prevent pellet disintegration and mistriggering of the arc initiation circuit. Results from the recent cryogenic operation of the two-stage pellet acceleration system are reported. 11 refs., 2 figs., 1 tab.

  1. Adult student satisfaction in an accelerated RN-to-BSN program: a follow-up study.

    Boylston, Mary T; Jackson, Christina

    2008-01-01

    This mixed-method study revealed accelerated RN-to-BSN (bachelor of science in nursing) students' levels of satisfaction with a wide range of college services in a small university. Building on seminal research on the topic [Boylston, M. T., Peters, M. A., & Lacey, M. (2004). Adult student satisfaction in traditional and accelerated RN-to-BSN programs. Journal of Professional Nursing, 20, 23-32.], the Noel-Levitz Adult Student Priorities Survey (ASPS) and qualitative interview data revealed primary factors involved in nontraditional (adult) accelerated RN-to-BSN student satisfaction. The ASPS assesses both satisfaction with and importance of the following factors: academic advising effectiveness, academic services, admissions and financial aid effectiveness, campus climate, instructional effectiveness, registration effectiveness, safety and security, and service excellence. Of these factors, participants considered instructional effectiveness and academic advising effectiveness as most important and concomitantly gave high satisfaction ratings to each. In contrast, convenience of the bookstore, counseling services, vending machines, and computer laboratories were given low importance ratings. The participants cited convenience as a strong marketing factor. Loss of financial aid or family crisis was given as a reason for withdrawal and, for most students, would be the only reason for not completing the BSN program. Outcomes of this investigation may guide faculty, staff, and administrators in proactively creating an educational environment in which a nontraditional student can succeed. PMID:18804082

  2. Review of Heavy-ion Induced Desorption Studies for Particle Accelerators

    Mahner, E

    2008-01-01

    During high-intensity heavy-ion operation of several particle accelerators worldwide, large dynamic pressure rises of orders of magnitude were caused by lost beam ions that impacted under grazing angle onto the vacuum chamber walls. This ion-induced desorption, observed, for example, at CERN, GSI, and BNL, can seriously limit the ion intensity, luminosity, and beam lifetime of the accelerator. For the heavyion program at CERN's Large Hadron Collider collisions between beams of fully stripped lead (208Pb82+) ions with a beam energy of 2.76 TeV/u and a nominal luminosity of 10**27 cm**-2 s**-1 are foreseen. The GSI future project FAIR (Facility for Antiproton and Ion Research) aims at a beam intensity of 10**12 uranium (238U28+) ions per second to be extracted from the synchrotron SIS18. Over the past years an experimental effort has been made to study the observed dynamic vacuum degradations, which are important to understand and overcome for present and future particle accelerators. The paper reviews the resu...

  3. To study the emittance dilution in Superconducting Linear Accelerator Design for International Linear Collider (ILC)

    Ranjan, Kirti; Solyak, Nikolay; Tenenbaum, Peter

    2005-04-01

    Recently the particle physics community has chosen a single technology for the new accelerator, opening the way for the world community to unite and concentrate resources on the design of an International Linear collider (ILC) using superconducting technology. One of the key operational issues in the design of the ILC will be the preservation of the small beam emittances during passage through the main linear accelerator (linac). Sources of emittance dilution include incoherent misalignments of the quadrupole magnets and rf-structure misalignments. In this work, the study of emittance dilution for the 500-GeV center of mass energy main linac of the Superconducting Linear Accelerator design, based on adaptation of the TESLA TDR design is performed using LIAR simulation program. Based on the tolerances of the present design, effect of two important Beam-Based steering algorithms, Flat Steering and Dispersion Free Steering, are compared with respect to the emittance dilution in the main linac. We also investigated the effect of various misalignments on the emittance dilution for these two steering algorithms.

  4. [Anti-aging studies on the senescence accelerated mouse (SAM) strains].

    Takahashi, Ryoya

    2010-01-01

    Senescence accelerated mouse (SAM), a murine model of accelerated senescence, was established by Toshio Takeda and colleagues. SAM consists of series of SAMP (prone) and SAMR (resistant) lines. All SAMP lines (from SAMP1 to SAMP11) are characterized by accelerated accumulation of senile features, earlier onset and faster progress of age-associated pathological phenotypes, such as amyloidosis, impaired immune response, senile osteoporosis and deficits in learning and memory. These SAMP lines are useful for evaluation of putative anti-aging therapies. For example, SAMP1 line is used to study the anti-aging effect of the antioxidant containing foods and various anti-oxidants, such as coenzyme Q10, vitamin C, lycopene. SAMP8 line exhibiting an early onset of impaired learning and memory is often used for test strategies for therapeutic intervention of dementia of early onset. SAMP6 is used as an animal model for developing new strategies for the treatment of osteoporosis in humans. Various lines of SAM (P1, P6, P8, P10 and R1) are now commercially available for research. In this review, I will briefly introduce various usages of SAM in anti-aging research. PMID:20046059

  5. Study and optimization of a LINAC drift tube for high intensity proton acceleration

    High intensity proton accelerators lead to specific problems related to the need to limit beam losses. The problem is more acute in the low energy part (up to 20 MeV) where the beam transport is the most difficult. The drift tube linac (DTL) remains the reference structure for energies of a few MeV to a few dozens MeV despite the arising of some new cavity types. This thesis purpose is to design such a DTL for a high intensity proton accelerator. Until now, no such continuous wave cavity has ever been operated. To ensure the viability of such an accelerator, a short four cells prototype is designed, built and tested under nominal RF conditions. This prototype is fully representative of a complete machine except for its length. The design complexity comes from the combination of RF electromagnetism, thermal exchanges, mechanics, ultra-vacuum engineering and manufacturing constraints. More specifically, the electromagnets alignment is a primary factor, and reliability, despite being usually of secondary importance in particles accelerator science, is here a major concern considering potential industrial applications of this machine. The prototype design includes the cavity itself, but also quadrupole electromagnets whose feasibility is a limiting factor, considering the very small space available to them. Two different magnet types and associated drift tubes are studied and manufactured, to be tested in the prototype cavity. The experimental part is focused on mechanical and thermal aspects. The electromagnetic properties of the cavity are also checked. As a conclusion of this thesis, technical and conceptual improvements as suggested by the manufacturing and experimental phases are presented, to be implemented in a complete cavity. (author)

  6. Neutronic studies in support of accelerator-driven systems: The MUSE experiments in the MASURCA facility

    Soule, R.; Assal, W.; Chaussonnet, P.; Destouches, C.; Domergue, C.; Jammes, C.; Laurens, J.-M.; Lebrat, J.-F.; Mellier, F.; Perret, G.; Rimpault, G.; Servière, H.; Imel, G.; M. Thomas, G.; VILLAMARIN D.

    2004-01-01

    The MUSE program (multiplication with an external source) is in progress at the MASURCA critical facility at the Cadarache Research Center of the Commissariat à l'Energie Atomique in France. The program is dedicated to the physics studies of accelerator-driven systems in support of transmutation studies of minor actinides and long-lived fission products. It began in 1995 with the coupling of a Cf source in MASURCA and was followed by a commercial (d,T) source. In 2001, a specially constructed...

  7. Experimental Study of an ion cyclon resonance accelerator presentation of his thesis

    Ramsell, C T

    1999-01-01

    The Ion Cyclotron Resonance Accelerator (ICRA) uses the operating principles of cyclotrons and gyrotrons. The novel geometry of the ICRA allows an ion beam to drift axially while being accelerated in the azimuthal direction. Previous work on electron cyclotron resonance acceleration used waveguide modes to accelerate an electron beam [5]. This research extends cyclotron resonance acceleration to ions by using a high field superconducting magnet and an rf driven magnetron operating at a harmonic of the cyclotron frequency. The superconducting solenoid provides an axial magnetic field for radial confinement and an rf driven magnetron provides azimuthal electric fields for acceleration. The intent of the ICRA concept is to create an ion accelerator which is simple, compact, lightweight, and inexpensive. Furthermore, injection and extraction are inherently simple since the beam drifts through the acceleration region. However, use of this convenient geometry leads to an accelerated beam with a large energy spread....

  8. Fractomechanical study of stress corrosion from Zircaloy-4

    The susceptibility to stress corrosion (SC) from Zircaloy-4 wires in iodine solutions in different alcohols and in aqueous IM solutions of NaCl, KBr and K1 has been studied before. The study of fracture surfaces showed in all cases intragranular attack followed by transgranular propagation. The intragranular fracture, that was associated with intragranular attack accompanied by stress, progresses until it penetrates the material and then the transition to transgranular fracture mode occurs, which has been identified as the 'true' SC process. For this transition to occur a certain value for the stress intensity factor (K1) has to be attained independently of the corrosive medium that produces the SC. In the case of alcoholic solutions, the K1 value obtained is almost constant and independent of the alcohol used as a solvent (10 Mpa.m-1/2).The average value of K1 calculated for the intergranular-transgranular transition of Zry-4 in aqueous halogenous solutions is 10.3±1.8 Mpa.m-1/2. This value agrees with the results found in the literature measured with different techniques and using different test geometries (Cw)

  9. Stress analysis studies in optimised 'D' shaped TOKAMAK magnet designs

    A suite of computer programs TOK was developed which enabled simple data input to be used for computation of magnetic fields and forces in a toroidal system of coils with either D-shaped or circular cross section. An additional requirement was that input data to the Swansea stress analysis program FINESSE could be output from the TOK fields and forces program, and that graphical output from either program should be available. A further program was required to optimise the coil shape. This used the field calculating routines from the TOK program. The starting point for these studies was the proposed 40 coil Princeton design. The stresses resulting from three different shapes of D-coil were compared. (author)

  10. Study of thermal stress in heat affected zones during welding

    The importance of applications of welding in the nuclear industry leads to the study of the main problem concerning metal welding: sensibility to cracking. The development of computation methods allows the numerical simulation of welding effects. Due to the complexity of this problem, it is divided in three steps: thermal, metallurgical and mechanical calculus. Interactions between the 3 steps are examined. Mathematical models necessary to get residual stress (i.e. stress remaining when welding is completed and structure at ambient temperature) are described. Then parameters for metallurgical structure determination are given and compared to experiments. A508 and A533 type steels of primary coolant circuit of PWR reactors are taken as examples and the numerical simulation of a test is presented

  11. SEM studies of stressed and irradiated Climax Stock quartz monzonite

    In an effort to find the mechanism by which gamma irradiation weakens the unconfined compressive strength of Climax Stock quartz monzonite (CSQM), sections of rock which had been irradiated and loaded to near failure were studied by scanning electron microscopy and compared to sections of rock which had been loaded but not irradiated. The quantities measured and compared were numbers and lengths of microfractures in the rock. We found that the crack parameters depended neither on irradiation treatment nor even on stress history, except in one sample which actually failed. By comparison to cracks counted in other granites by other workers, the crack statistics on CSQM are much noisier and much less indicative of stress history. CSQM is structurally more heterogeneous than the other granites, which is probably the cause of the greater noise level. 12 references, 3 figures, 5 tables

  12. Study of an accelerating superconducting module and its feedback loop systems for the MYRRHA project

    The MYRRHA ( Multi-purpose hybrid Research Reactor for High-tech Applications ) project aims at constructing an accelerator driven system (ADS) demonstrator (50 a 100 MWth) to explore the feasibility of nuclear waste transmutation. Such a subcritical reactor requires an extremely reliable accelerator which delivers a CW high power protons beam (600 MeV, 4 mA). The reference solution for this machine is a superconducting linear accelerator. This thesis presents the work - undertaken at IPN Orsay in October 2008 - on the study of a prototypical superconducting module and the feedback control systems of its cavity for the high energy part of the MYRRHA linac. First, the optimization and the design of 5-cell elliptical cavities (β=0,65), operating at 704.4 MHz, are presented. Then, the experimental work focuses on a reliability oriented study of the 'cryo-module' which hold a prototypical 5-cell cavity (β=0,47). In this study, the dynamic behavior of the fast tuning system of the cavity was measured and qualified. The 'field flatness' issue in 'low beta' multi-cell cavity was also brought to light. Finally, a fault-tolerance analysis of the linac was carried out. Toward this goal, a model of the cavity, its RF feedback loop system and its tuning system feedback loop was developed. This study enabled to determine the RF power needs, the tuning system requirements and as well as to demonstrate the feasibility of fast fault-recovery scenarios to minimize the number of beam interruptions in the MYRRHA linac. (author)

  13. Micromechanical studies of cyclic creep fracture under stress controlled loading

    van der Giessen, Erik; Tvergaard, Viggo

    This paper deals with a study of intergranular failure by creep cavitation under stress-controlled cyclic loading conditions. Loading is assumed to be slow enough that diffusion and creep mechanisms (including grain boundary sliding) dominate, leading to intergranular creep fracture. This study is...... case with a facet-site microcrack yields important insight for damage accumulation under balanced loading. Under unbalanced loading, the time-average accumulation of creep cavitation gives rise to macroscopic ratchetting, while its rate is demonstrated to depend subtly on material and loading...

  14. Laboratory stress corrosion cracking studies in polythionic acid

    Baylor, V.B.; Newsome, J.F.

    1984-08-01

    Stress corrosion cracking caused by polythionic acid and/or chlorides is a problem in coal liquefaction pilot plants. This problem is also common in refineries and has been the subject of extensive research. This study examines (1) the relationship of the ASTM standard ferric sulfate-sulfuric acid test for determining sensitization to resistance to polythionic stress corrosion cracking, (2) the cracking resistance of higher-alloy Fe-Ni-Cr materials in addition to the common austenitic stainless steels, and (3) the effect of chloride concentrations up to 1% in polythionic acid solutions on cracking behavior. We found that the ferric sulfate-sulfuric acid test can be used as an acceptance test for materials resistant to polythionic acid stress corrosion cracking because of its severity. The more highly alloyed materials were more resistant to sensitization than most of the austenitic stainless steels and were virtually unattacked in polythionic acid solutions containing up to 1% chloride. Chloride increased the corrosion rate and caused localized pitting, but it did not affect significantly the number of failures or the failure mode.

  15. Study of the pulsation of an ion accelerator giving 20 nano-second pulses

    In order to measure fast neutron spectra by the time-of-flight method, we have studied a pulsed ion-source which has been placed on the 600 kV electrostatic accelerator at Fontenay-aux-Roses. We examine successively: the ion-source itself, its extraction device, the focussing equipment and the pulsation system constituted by a slit which is swept by the beam. Using this ion-source it is possible to obtain a direct current of deutons of over 800 μA, and clouds having a duration which can be adjusted to between 15 and 40 nano-seconds. (author)

  16. Study of recirculating induction accelerator as drivers for heavy ion fusion

    Two years ago, Lawrence Livermore National Laboratory (LLNL) began a study of the viability and relative utility of recirculating induction accelerators as drivers for Heavy Ion Fusion (HIF). The final draft of the report detailing the results in 284 pages was completed in September, 1991. As well as broadly involving the collaboration of many researchers from several groups at LLNL, it also benefited from contributions from several individuals in the HIF program at Lawrence Berkeley Laboratory and from others in the HIF community nationwide. This presentation summarizes the key findings given in that report

  17. Stress.

    Chambers, David W

    2008-01-01

    We all experience stress as a regular, and sometimes damaging and sometimes useful, part of our daily lives. In our normal ups and downs, we have our share of exhaustion, despondency, and outrage--matched with their corresponding positive moods. But burnout and workaholism are different. They are chronic, dysfunctional, self-reinforcing, life-shortening habits. Dentists, nurses, teachers, ministers, social workers, and entertainers are especially susceptible to burnout; not because they are hard-working professionals (they tend to be), but because they are caring perfectionists who share control for the success of what they do with others and perform under the scrutiny of their colleagues (they tend to). Workaholics are also trapped in self-sealing cycles, but the elements are ever-receding visions of control and using constant activity as a barrier against facing reality. This essay explores the symptoms, mechanisms, causes, and successful coping strategies for burnout and workaholism. It also takes a look at the general stress response on the physiological level and at some of the damage American society inflicts on itself. PMID:18846841

  18. Treatment of nasopharyngeal carcinoma using simultaneous modulated accelerated radiation therapy via helical tomotherapy: a phase II study

    Du Lei

    2016-06-01

    Full Text Available The aim of the study was to evaluate short-term safety and efficacy of simultaneous modulated accelerated radiation therapy (SMART delivered via helical tomotherapy in patients with nasopharyngeal carcinoma (NPC.

  19. Theoretical and numerical studies on the transport of transverse beam quality in plasma-based accelerators

    Mehrling, Timon

    2014-01-01

    This work examines effects, which impact the transverse quality of electron-beams in plasma-based accelerators, by means of theoretical and numerical methods. Plasma-based acceleration is a promising candidate for future particle accelerator technologies. In plasma-based acceleration, highly intense laser beams or high-current relativistic particle beams are focused into a plasma to excite plasma-waves with extreme transverse and longitudinal electric fields. The amplitude of these fields exc...

  20. LAVENDER: A steady-state core analysis code for design studies of accelerator driven subcritical reactors

    Zhou, Shengcheng; Wu, Hongchun; Cao, Liangzhi; Zheng, Youqi, E-mail: yqzheng@mail.xjtu.edu.cn; Huang, Kai; He, Mingtao; Li, Xunzhao

    2014-10-15

    Highlights: • A new code system for design studies of accelerator driven subcritical reactors (ADSRs) is developed. • S{sub N} transport solver in triangular-z meshes, fine deletion analysis and multi-channel thermal-hydraulics analysis are coupled in the code. • Numerical results indicate that the code is reliable and efficient for design studies of ADSRs. - Abstract: Accelerator driven subcritical reactors (ADSRs) have been proposed and widely investigated for the transmutation of transuranics (TRUs). ADSRs have several special characteristics, such as the subcritical core driven by spallation neutrons, anisotropic neutron flux distribution and complex geometry etc. These bring up requirements for development or extension of analysis codes to perform design studies. A code system named LAVENDER has been developed in this paper. It couples the modules for spallation target simulation and subcritical core analysis. The neutron transport-depletion calculation scheme is used based on the homogenized cross section from assembly calculations. A three-dimensional S{sub N} nodal transport code based on triangular-z meshes is employed and a multi-channel thermal-hydraulics analysis model is integrated. In the depletion calculation, the evolution of isotopic composition in the core is evaluated using the transmutation trajectory analysis algorithm (TTA) and fine depletion chains. The new code is verified by several benchmarks and code-to-code comparisons. Numerical results indicate that LAVENDER is reliable and efficient to be applied for the steady-state analysis and reactor core design of ADSRs.

  1. Studies on the particle dynamics in high-frequency quadrupole accelerators

    In the present thesis the particle dynamics in rf quadrupole accelerators (RFQ) was studied. First the analytic theory of the particle motion is presented which results directly from the equations of motion. From this follow especially equations for the maximally transportable current strength in a RFQ accelerator. Because this theory however is at higher phase shift no longer correct and can in this case only serve as approximational method and because also the anharmonic longitudinal motion was linearized it was necessary to study the particle dynamics by means of numerical solution of the equations of motion, by the PARMTEQ program the equations of motion were directly integrated whereby the space-charge effect can be included. The comparison of the simulation calcualtion with the analytic theory and the test of both in the experiment was at first performed for the proton model of a heavy ion RFQ. An essential object of the study was hereby the influence of the higher harmonics of the field distribution on the particle dynamics which were at the proton model especially high because of a low transverse phase shift. (orig./HSI)

  2. Step-stress Accelerated Degradation Testing for Solar Reflectors%美国太阳反射镜步进应力加速老化试验

    李迪凡; 张凯; 张燕; 符朝旭; 朱玉琴

    2014-01-01

    To meet the challenge of reducing the cost of electricity generated with concentrating solar power (CSP), new low-cost reflector materials are being developed, including metalized polymer reflectors. By being exposed solar reflec-tors to UV-light, we used the application of testing methods and statistical inference techniques to quantitative evaluate and improve service lifetime of solar reflectors associated with failure mechanisms, which are exposed to UV-light. We will take advantage of the Ultra Accelerated Weathering System (UAWS) to assess various degradation patterns caused by acceler-ated aging because of exposing to UV. On account of numbers of samples, test conditions, performance degradation, failure patterns and other reasons, the test results may be used to further deduce failure mechanisms, associated physical parame-ters, service lifetimes, and uncertainties. In necessary and complicated circumstances, we can use advanced planning and statistical inference, and propose step-stress accelerated degradation testing (SSADT) methods.%为了应对降低聚光发电(CSP)成本带来的挑战,研发新型的低成本反射镜材料,包括金属聚合物反射镜。通过将太阳反射镜暴露在紫外光下,利用试验应用方法和统计推论技术,定量评估和改进太阳光反射镜在紫外光下与失效机制相关的使用寿命。将利用超加速环境系统评估由紫外暴露加速老化导致的多种性能退化模式。由于样品数量、试验条件、性能退化和失效模式等原因,试验结果可用于深入推导失效机制、关联物理参数、服役寿命和不确定性。在有必要利用高级方案和统计推论的复杂情况下,建议采用步进应力加速老化试验方法。

  3. Dynamic imaging and hydrodynamics study of high velocity, laser-accelerated thin foil targets using multiframe optical shadowgraphy

    S Tripathi; S Chaurasia; P Leshma; L J Dhareshwar

    2012-12-01

    The main aim of the study of thin target foil–laser interaction experiments is to understand the physics of hydrodynamics of the foil acceleration, which is highly relevant to inertial confinement fusion (ICF). This paper discusses a simple, inexpensive multiframe optical shadow-graphy diagnostics developed for dynamic imaging of high velocity laser-accelerated target foils of different thicknesses. The diagnostic has a spatial and temporal resolution of 12 m and 500 ps respectively in the measurements. The target velocity is in the range of 106 - 107 cm/s. Hydrodynamic efficiency of such targets was measured by energy balance experiments together with the measurement of kinetic energy of the laser-driven targets. Effect of target foil thickness on the hydrodynamics of aluminum foils was studied for determining the optimum conditions for obtaining a directed kinetic energy transfer of the accelerated foil. The diagnostics has also been successfully used to study ablatively accelerated targets of other novel materials.

  4. A community study on the relationship between stress, coping, affective dispositions and periodontal attachment loss

    Leung, WK; Ng, SKS

    2006-01-01

    Background: Psychological factors may increase the risk for periodontal diseases. Contemporary conceptualization of the stress process supports the evaluation of stress at three levels: stressors, moderating and mediating factors, and stress reactions. Objective: This study was undertaken to investigate the relationship of periodontal disease in terms of clinical attachment level (CAL) to psychosocial stress, making reference to the major components of stress process. Methods: A cross-section...

  5. Study of resistance change and open failure at stripe and viahole by stress-migration

    Wada, T.; Hata, Y.

    1992-08-01

    Through investigation of stress-migration, the following have been found. 1. The resistance of a stripe decreases by mechanical stress and/or temperature below the temperature of annealing. The ratio of decrease of resistance will be the important factor for the study of stress-migration. 2. These sample structure with long lifetime on electromigration, does not always have long lifetime on stress-migration. 3. Al-Si-Cu has a strong stress-migration resistance. For relaxation of stress, Cu segregates at the aluminum grain boundary and the resistance decreases. 4. Stress induced open failure occurred at viaholes. This failure depends on the size of the viahole.

  6. Study on focusing characteristic of acceleration tube in high current implanter

    The accelerating tube is one of the most important parts in high current implanter which provides the desired energy and focusing for ion beam. The factors affecting focus characteristic in high current implanter with three gap acceleration tube are discussed. Focusing degrees of different energy ion beam are computed, and the electric field required to prevent beam expansion due to space charge effect are analyzed. The beam envelope inside the three acceleration gap shows a decrease of the beam radius with the increase of the accelerating voltage ratio up to the optimal value. Beyond this optimal value the beam lines make a crossover with the axis of the accelerating tube

  7. Study of field-limiting defects in superconducting RF cavities for electron-accelerators

    Superconducting radio-frequency resonators made from niobium are an integral part of many accelerator projects. Their main advantage are the low ohmic losses resulting in the possibility for a long pulse structure and high duty cycles up to continous wave (cw) operation. The European X-Ray Free-Electron Laser (XFEL) and the International Linear Collider (ILC) are based on this technology. In some cases the resonators reach accelerating electric fields close to the theoretical limit of bulk niobium. Yet most resonators are limited at lower fields and mass production for large scale accelerator projects suffers from the spread in the achievable gradient per resonator. The main limitations are field emission and the breakdown of superconductivity (quench). While field emission is mostly attributed to the overall surface cleanliness of the resonator, quench is usually associated with local defects. Optical inspection of the inner surface of the resonators with unprecedented resolution, accuracy and a special illumination has been established at DESY and used to study such local surface defects. More than 30 resonators have been inspected. Distinctive features from these inspections have been catalogued and assessed for their potential risk for the performance of the resonator. Several confirmed quenching defects could be extracted for further analysis and could be traced back to likely origins in the production process. A new, automated set-up for optical inspection of large series of resonators, named OBACHT, has been developed and successfully commissioned. Its design includes the minimal need for operator interference, reproducibility, robustness and versatility, in order to fit the requirements for application both in a laboratory and in a production environment. To facilitate the comparison of the results obtained during the global R and D effort on resonators for the ILC, the ILC global yield database has been established. The yield and selection rules for the

  8. Injector and beam transport simulation study of proton dielectric wall accelerator

    Zhao, Quantang, E-mail: zhaoquantang@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China); Yuan, P.; Zhang, Z.M.; Cao, S.C [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Shen, X.K. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China); Jing, Y.; Ma, Y.Y. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Yu, C.S. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China); Li, Z.P.; Liu, M.; Xiao, R.Q.; Zhao, H.W. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China)

    2012-12-01

    A simulation study of a short-pulsed proton injector for, and beam transport in, a dielectric wall accelerator (DWA) has been carried out using the particle-in-cell (PIC) code Warp. It was shown that applying 'tilt pulse' voltage waveforms on three electrodes enables the production of a shorter bunch by the injector. The fields in the DWA beam tube were simulated using Computer Simulation Technology's Microwave Studio (CST MWS) package, with various choices for the boundary conditions. For acceleration in the DWA, the beam transport was simulated with Warp, using applied fields obtained by running CST MWS. Our simulations showed that the electric field at the entrance to the DWA represents a challenging issue for the beam transport. We thus simulated a configuration with a mesh at the entrance of the DWA, intended to improve the entrance field. In these latter simulations, a proton bunch was successfully accelerated from 130 keV to about 36 MeV in a DWA with a length of 36.75 cm. As the beam bunch progresses, its transverse dimensions diminish from (roughly) 0.5 Multiplication-Sign 0.5 cm to 0.2 Multiplication-Sign 0.4 cm. The beam pulse lengthens from 1 cm to 2 cm due to lack of longitudinal compression fields. -- Highlights: Black-Right-Pointing-Pointer A pulse proton injector with tilt voltages on the three electrodes was simulated. Black-Right-Pointing-Pointer The fields in different part of the DWA were simulated with CST and analyzed. Black-Right-Pointing-Pointer The proton beam transport in DWA was simulated with Warp successfully. Black-Right-Pointing-Pointer The simulation can help for designing a real DWA.

  9. Injector and beam transport simulation study of proton dielectric wall accelerator

    A simulation study of a short-pulsed proton injector for, and beam transport in, a dielectric wall accelerator (DWA) has been carried out using the particle-in-cell (PIC) code Warp. It was shown that applying “tilt pulse” voltage waveforms on three electrodes enables the production of a shorter bunch by the injector. The fields in the DWA beam tube were simulated using Computer Simulation Technology’s Microwave Studio (CST MWS) package, with various choices for the boundary conditions. For acceleration in the DWA, the beam transport was simulated with Warp, using applied fields obtained by running CST MWS. Our simulations showed that the electric field at the entrance to the DWA represents a challenging issue for the beam transport. We thus simulated a configuration with a mesh at the entrance of the DWA, intended to improve the entrance field. In these latter simulations, a proton bunch was successfully accelerated from 130 keV to about 36 MeV in a DWA with a length of 36.75 cm. As the beam bunch progresses, its transverse dimensions diminish from (roughly) 0.5×0.5 cm to 0.2×0.4 cm. The beam pulse lengthens from 1 cm to 2 cm due to lack of longitudinal compression fields. -- Highlights: ► A pulse proton injector with tilt voltages on the three electrodes was simulated. ► The fields in different part of the DWA were simulated with CST and analyzed. ► The proton beam transport in DWA was simulated with Warp successfully. ► The simulation can help for designing a real DWA.

  10. Supernova / Acceleration Probe: A Satellite Experiment to Study the Nature of the Dark Energy

    Aldering, G; Amanullah, R; Annis, J; Astier, Pierre; Baltay, C; Barrelet, E; Basa, S; Bebek, C; Bergström, L; Bernstein, G; Bester, M; Bigelow, B; Blandford, R D; Bohlin, R; Bonissent, A; Bower, C; Brown, M; Campbell, M; Carithers, W; Commins, Eugene D; Craig, W; Day, C; De Jongh, F; Deustua, S; Diehl, T; Dodelson, S; Ealet, A; Ellis, R; Emmet, W; Fouchez, D; Frieman, J A; Fruchter, A; Gerdes, D; Gladney, L; Goldhaber, G; Goobar, A; Groom, D; Heetderks, H; Hoff, M; Holland, S; Huffer, M; Hui, L; Huterer, D; Jain, B; Jelinsky, P N; Karcher, A; Kent, S; Kahn, S; Kim, A; Kolbe, W; Krieger, B; Kushner, G; Kuznetsova, N; Lafever, R; Lamoureux, J; Lampton, M; Lefèvre, O; Levi, M; Limon, P; Lin, H; Linder, E; Loken, S; Lorenzon, W; Malina, R; Marriner, J P; Marshall, P; Massey, R; Mazure, A; McKay, T; McKee, S; Miquel, R; Morgan, N; Mortsell, E; Mostek, N; Mufson, S; Musser, J; Nugent, P; Olus, H; Pain, R; Palaio, N; Pankow, D; Peoples, John; Perlmutter, S; Prieto, E; Rabinowitz, D; Réfrégier, A; Rhodes, J; Roe, N; Rusin, D; Scarpine, V; Schubnell, M; Sholl, M; Smadja, G; Smith, R M; Smoot, George F; Snyder, J; Spadafora, A; Stebbins, A; Stoughton, C; Szymkowiak, A; Tarle, G; Taylor, K; Tilquin, A; Tomasch, A; Tucker, D; Vincent, D; Von der Lippe, H; Walder, J P; Wang, G; Wester, W

    2004-01-01

    The Supernova / Acceleration Probe (SNAP) is a proposed space-based experiment designed to study the dark energy and alternative explanations of the acceleration of the Universe's expansion by performing a series of complementary systematics-controlled measurements. We describe a self-consistent reference mission design for building a Type Ia supernova Hubble diagram and for performing a wide-area weak gravitational lensing study. A 2-m wide-field telescope feeds a focal plane consisting of a 0.7 square-degree imager tiled with equal areas of optical CCDs and near infrared sensors, and a high-efficiency low-resolution integral field spectrograph. The SNAP mission will obtain high-signal-to-noise calibrated light-curves and spectra for several thousand supernovae at redshifts between z=0.1 and 1.7. A wide-field survey covering one thousand square degrees resolves ~100 galaxies per square arcminute. If we assume we live in a cosmological-constant-dominated Universe, the matter density, dark energy density, and ...

  11. Study of high-energy particle acceleration in Tycho with gamma-ray observations

    Park, Nahee

    2015-01-01

    Gamma-ray emission from supernova remnants (SNRs) can provide a unique window to observe the cosmic-ray acceleration believed to take place in these objects. Tycho is an especially good target for investigating hadronic cosmic-ray acceleration and interactions because it is a young type Ia SNR that is well studied in other wavelengths, and it is located in a relatively clean environment. Several different theoretical models have been advanced to explain the broadband spectral energy emission of Tycho from radio to the gamma-ray emission detected by the Fermi-LAT in the GeV and by VERITAS in the TeV. We will present an update on the high-energy gamma-ray studies of Tycho with $\\sim150$ hours of VERITAS and $\\sim77$ months of the Fermi-LAT observations, which represents about a factor of two increase in exposure over previously published data. VERITAS data also include exposure with an upgraded camera, which made it possible to extend the TeV measurements toward lower energy, thanks to its improved low energy s...

  12. Comparison of Acceleration and Impact Stress as Possible Loading Factors in Phonation: A Computer Modeling Study

    Horáček, Jaromír; Laukkanen, A. M.; Šidlof, Petr; Murphy, P.; Švec, J. G.

    2009-01-01

    Roč. 61, č. 3 (2009), s. 137-145. ISSN 1021-7762 R&D Projects: GA ČR(CZ) GA101/08/1155 Institutional research plan: CEZ:AV0Z20760514 Keywords : biomechanics of voice modeling * fundamental frequency * phoniation type * gender differences in voice Subject RIV: BI - Acoustics Impact factor: 1.439, year: 2007

  13. Near-Surface Sensing of Vegetative Heavy Metal Stress: Method Development for an Accelerated Assessment of Mine Tailing Waste and Remediation Efforts

    Lee, M. T.; Gottfried, M.; Berglund, E.; Rodriguez, G.; Ceckanowicz, D. J.; Cutter, N.; Badgeley, J.

    2014-12-01

    The boom and bust history of mineral extraction in the American southwest is visible today in tens of thousands of abandoned and slowly decaying mine installations that scar the landscape. Mine tailing piles, mounds of crushed mineral ore, often contain significant quantities of heavy metal elements which may leach into surrounding soils, surface water and ground water. Chemical analysis of contaminated soils is a tedious and time-consuming process. Regional assessment of heavy metal contamination for treatment prioritization would be greatly accelerated by the development of near-surface imaging indices of heavy-metal vegetative stress in western grasslands. Further, the method would assist in measuring the ongoing effectiveness of phytoremedatian and phytostabilization efforts. To test feasibility we ground truthed nine phytoremediated and two control sites sites along the mine-impacted Kerber Creek watershed in Saguache County, Colorado. Total metal concentration was determined by XRF for both plant and soil samples. Leachable metals were extracted from soil samples following US EPA method 1312. Plants were identified, sorted into roots, shoots and leaves, and digested via microwave acid extraction. Metal concentrations were determined with high accuracy by ICP-OES analysis. Plants were found to contain significantly higher concentrations of heavy metals than surrounding soils, particularly for manganese (Mn), iron (Fe), copper (Cu), zinc (Zn), barium (Ba), and lead (Pb). Plant species accumulated and distributed metals differently, yet most showed translocation of metals from roots to above ground structures. Ground analysis was followed by near surface imaging using an unmanned aerial vehicle equipped with visible/near and shortwave infrared (0.7 to 1.5 μm) cameras. Images were assessed for spectral shifts indicative of plant stress and attempts made to correlate results with measured soil and plant metal concentrations.

  14. Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination

    Melillo Paolo; Bracale Marcello; Pecchia Leandro

    2011-01-01

    Abstract Background This study investigates the variations of Heart Rate Variability (HRV) due to a real-life stressor and proposes a classifier based on nonlinear features of HRV for automatic stress detection. Methods 42 students volunteered to participate to the study about HRV and stress. For each student, two recordings were performed: one during an on-going university examination, assumed as a real-life stressor, and one after holidays. Nonlinear analysis of HRV was performed by using P...

  15. Trauma and posttraumatic stress disorder in South Africa: analysis from the South African Stress and Health Study

    Atwoli, Lukoye; Stein, Dan J.; Williams, David R.; McLaughlin, Katie A.; Petukhova, Maria; Kessler, Ronald C.; Koenen, Karestan C

    2013-01-01

    Background: South Africa’s unique history, characterised by apartheid, a form of constitutional racial segregation and exploitation, and a long period of political violence and state-sponsored oppression ending only in 1994, suggests a high level of trauma exposure in the general population. The aim of this study was to document the epidemiology of trauma and posttraumatic stress disorder (PTSD) in the South African general population. Methods: The South African Stress and Health Study is a n...

  16. Experimental Studies Of W-band Accelerator Structures At High Field

    Hill, M E

    2001-01-01

    A high-gradient electron accelerator is desired for high- energy physics research, where frequency scalings of breakdown and trapping of itinerant beamline particles dictates operation of the accelerator at short wavelengths. The first results of design and test of a high-gradient mm-wave linac with an operating frequency at 91.392 GHz (W-band) are presented. A novel approach to particle acceleration is presented employing a planar, dielectric lined waveguide used for particle acceleration. The traveling wave fields in the planar dielectric accelerator (PDA) are analyzed for an idealized structure, along with a circuit equivalent model used for understanding the structure as a microwave circuit. Along with the W-band accelerator structures, other components designed and tested are high power rf windows, high power attenuators, and a high power squeeze-type phase shifter. The design of the accelerator and its components where eased with the aide of numerical simulations using a finite-difference electromagneti...

  17. Longitudinal study of group a bunch of electrons in a linear accelerator

    For an effective use of the electron beam, the energy dispersion shall have to be the weakest possible on the other hand the beam intensity owes shall be the biggest possible. In the practice these parameters depended of the bunching elements in the accelerator. The first part of our work presents studies concerning the influence of the modulation tension in the cavity and the drift space length on the bunching quality. The second part of this study is related to development an algorithm dedicated to determine the RF and geometrical parameters which influence the bunching quality. The studied case is a cavity followed by a drift space. The result obtained by application this algorithm is in good agreement with the others simulations result.

  18. Reproductive effort accelerates actuarial senescence in wild birds: an experimental study.

    Boonekamp, Jelle J; Salomons, Martijn; Bouwhuis, Sandra; Dijkstra, Cor; Verhulst, Simon

    2014-05-01

    Optimality theories of ageing predict that the balance between reproductive effort and somatic maintenance determines the rate of ageing. Laboratory studies find that increased reproductive effort shortens lifespan, but through increased short-term mortality rather than ageing. In contrast, high fecundity in early life is associated with accelerated senescence in free-living vertebrates, but these studies are non-experimental. We performed lifelong brood size manipulation in free-living jackdaws. Actuarial senescence--the increase in mortality rate with age--was threefold higher in birds rearing enlarged- compared to reduced broods, confirming a key prediction of the optimality theory of ageing. Our findings contrast with the results of single-year brood size manipulation studies carried out in many species, in which there was no overall discernible manipulation effect on mortality. We suggest that our and previous findings are in agreement with predictions based on the reliability theory of ageing and propose further tests of this proposition. PMID:24818237

  19. Experimental stand for studying the impact of laser-accelerated protons on biological objects

    Burdonov, K. F.; Eremeev, A. A.; Ignatova, N. I.; Osmanov, R. R.; Sladkov, A. D.; Soloviev, A. A.; Starodubtsev, M. V.; Ginzburg, V. N.; Kuz'min, A. A.; Maslennikova, A. V.; Revet, G.; Sergeev, A. M.; Fuchs, J.; Khazanov, E. A.; Chen, S.; Shaykin, A. A.; Shaikin, I. A.; Yakovlev, I. V.

    2016-04-01

    An original experimental stand is presented, aimed at studying the impact of high-energy protons, produced by the laser-plasma interaction at a petawatt power level, on biological objects. In the course of pilot experiments with the energy of laser-accelerated protons up to 25 MeV, the possibility is demonstrated of transferring doses up to 10 Gy to the object of study in a single shot with the magnetic separation of protons from parasitic X-ray radiation and fast electrons. The technique of irradiating the cell culture HeLa Kyoto and measuring the fraction of survived cells is developed. The ways of optimising the parameters of proton beams and the suitable methods of their separation with respect to energy and transporting to the studied living objects are discussed. The construction of the stand is intended for the improvement of laser technologies for hadron therapy of malignant neoplasms.

  20. Stress analysis of glass-canister interaction: a study of residual stresses and fracturing

    Residual stresses and cracking in canisters filled with vitrified nuclear waste are simulated using finite element computer calculations. Cooling rates, internal heat generation, and thermal expansion coefficients significantly affect stress levels. Glass behavior within the softening temperature range is taken to follow the instant freezing concept of Bartenev

  1. Biotechnological Approaches to Study Plant Responses to Stress

    Pérez-Clemente, Rosa M; Vicente Vives; Zandalinas, Sara I.; López-Climent, María F.; Valeria Muñoz; Aurelio Gómez-Cadenas

    2013-01-01

    Multiple biotic and abiotic environmental stress factors affect negatively various aspects of plant growth, development, and crop productivity. Plants, as sessile organisms, have developed, in the course of their evolution, efficient strategies of response to avoid, tolerate, or adapt to different types of stress situations. The diverse stress factors that plants have to face often activate similar cell signaling pathways and cellular responses, such as the production of stress proteins, upre...

  2. Proteomic studies of drought stress response in Fabaceae

    Zadražnik, Tanja; Jelka ŠUŠTAR-VOZLIČ

    2015-01-01

    Drought stress is a serious threat to crop production that influences plant growth and development and subsequently causes reduced quantity and quality of the yield. Plant stress induces changes in cell metabolism, which includes differential expression of proteins. Proteomics offer a powerful approach to analyse proteins involved in drought stress response of plants. Analyses of changes in protein abundance of legumes under drought stress are very important, as legumes play an important role...

  3. Depression and ways of coping with stress: A preliminary study

    Orzechowska, Agata; Zajączkowska, Marlena; Talarowska, Monika; Gałecki, Piotr

    2013-01-01

    Background Coping with stress is defined as all activities undertaken by a human in a stressful situation. The effect of stress on depression, its role in triggering the subsequent phases of the disease, and the factors that mediate the stress-depression relationship become more and more often subjects of research in psychiatry and psychology. Factors important for the formation of depressive symptoms and disease progression are significantly associated with coping strategies used in the face...

  4. Prospective community study of family stress and anxiety in (pre)adolescents: the TRAILS study

    Oort, Floor V. A.; Verhulst, Frank C.; Ormel, Johan; Huizink, Anja C.

    2009-01-01

    International audience For prevention of anxiety in children and adolescents, it is important to know whether family stress is a predictor of anxiety. We studied this in 1,875 adolescents from the Tracking Adolescents' Individual Lives Survey (TRAILS) who were followed up for 2 years, from age 10–12 to 12–14 years. Adolescents reported anxiety and depression symptoms at both assessments, and parents reported family stress (family dysfunction and parenting stress) at the first assessment. F...

  5. Laboratory studies of magnetized collisionless flows and shocks using accelerated plasmoids

    Weber, T. E.; Smith, R. J.; Hsu, S. C.

    2015-11-01

    Magnetized collisionless shocks are thought to play a dominant role in the overall partition of energy throughout the universe, but have historically proven difficult to create in the laboratory. The Magnetized Shock Experiment (MSX) at LANL creates conditions similar to those found in both space and astrophysical shocks by accelerating hot (100s of eV during translation) dense (1022 - 1023 m-3) Field Reversed Configuration (FRC) plasmoids to high velocities (100s of km/s); resulting in β ~ 1, collisionless plasma flows with sonic and Alfvén Mach numbers of ~10. The FRC subsequently impacts a static target such as a strong parallel or anti-parallel (reconnection-wise) magnetic mirror, a solid obstacle, or neutral gas cloud to create shocks with characteristic length and time scales that are both large enough to observe yet small enough to fit within the experiment. This enables study of the complex interplay of kinetic and fluid processes that mediate cosmic shocks and can generate non-thermal distributions, produce density and magnetic field enhancements much greater than predicted by fluid theory, and accelerate particles. An overview of the experimental capabilities of MSX will be presented, including diagnostics, selected recent results, and future directions. Supported by the DOE Office of Fusion Energy Sciences under contract DE-AC52-06NA25369.

  6. submitter Radiation Protection Studies for CERN LINAC4/SPL Accelerator Complex

    Mauro, Egidio; Silari, Marco

    2009-01-01

    CERN is presently designing a new chain of accelerators to replace the present Proton Synchrotron (PS) complex: a 160 MeV room-temperature H$^-$ linac (Linac4) to replace the present 50 MeV proton linac injector, a 3.5 GeV Superconducting Proton Linac (SPL) to replace the 1.4 GeV PS booster (PSB) and a 50 GeV synchrotron (named PS2) to replace the 26 GeV PS. Linac4 has been funded and the civil engineering work started in October 2008, whilst the SPL is in an advanced stage of design. Beyond injecting into the future 50 GeV PS, the ultimate goal of the SPL is to generate a 4 MW beam for the production of intense neutrino beams. The radiation protection design is driven by the latter requirement. This thesis summarizes the radiation protection studies conducted for Linac4. FLUKA Monte Carlo simulations, complemented by analytical estimates, were performed 1) to evaluate the propagation of neutrons through the waveguide, ventilation and cable ducts placed along the accelerator, 2) to estimate the radiological i...

  7. Plasma-Surface Interaction Research At The Cambridge Laboratory Of Accelerator Studies Of Surfaces

    The material requirements for plasma-facing components in a nuclear fusion reactor are some of the strictest and most challenging facing us today. These materials are simultaneously exposed to extreme heat loads (20 MW/m2 steady-state, 1 GW/m2 in millisecond transients) and particle fluxes (>1024 m-2 s-1) while also undergoing high neutron irradiation (1018 neutrons/m2 s). At the Cambridge Laboratory of Accelerator Studies of Surfaces (CLASS), many of the most important issues in plasma-surface interaction research, such as plasma-driven material erosion and deposition, material transport and irradiation and hydrogenic retention are investigated with the use of a 1.7 MV tandem ion accelerator. Ion-Beam Analysis (IBA) is used to investigate and quantify changes in materials due to plasma exposure and ion irradiation is used as a proxy for neutron irradiation to investigate plasma-surface interactions for irradiated materials. This report will outline the capabilities and current research activities at CLASS.

  8. A study on radiation treatment of wastewater using an electron accelerator

    A study on radiation oxidation treatment of refractory or toxic wastewater using an electron accelerator was carried out from the viewpoint of reaction engineering. For the process using electron beams, oxygen supply to the penetration range of electron (reaction zone) where the dose rate is extremely high, is significantly important. A concentric dual-tube-type bubbling column reactor was shown to be most suitable to maintain the dissolved oxygen at a high concentration. Rate expressions of pollutant reduction and oxygen consumption in the reactor were derived. The efficiency of active species utilization for oxidation, phi, was defined and shown to be an important design parameter. A new wastewater treatment system (Electron Accelerator-Dual tube Bubbling Reactor system) was proposed, and successfully demonstrated for the treatment of wastewater involving dyes and phenol. The dissolved oxygen was maintained at a high concentration by using this type of reactor for the high dose rate irradiation. phi was obtained as a function of dissolved oxygen concentration for the dye solution and was also obtained as functions of the oxygen concentration and dose rate for the phenol solution. By these experimental results, the effectiveness of EA-DBR system was proved. (author)

  9. Simulation study of an accelerator driven as a transmutation and energy generation system

    In twenty first century world is facing two issues of future concern, generation of clean energy and the protection of the environment. Oil price is soaring to a level of jeopardizing world economy and on the other hand burning fossil fuel is reaching to a point of endangering life of all creatures. The sole solution to compete the energy shortage is exploiting nuclear energy and other clean energy sources. The main concern of nuclear energy is long term radioactive waste. In principle, any nuclear reactor is able to burn and transmute minor actinides, but reactors with fast neutron spectrum must be preferred, as they allow a positive neutron gain throughout the burning process. A core dedicated to the transmutation of the minor actinides should be designed in order to minimize its self-production of actinides. A possible solution to these problems is represented by a subcritical system driven by an accelerator, which is able to safely bum and/or transmute actinides and long lived fission products, as it does not rely on delayed neutrons for control or power change and the reactivity feedbacks have only limited importance during transient response. In this study, an accelerator driven system based on Japanese design was simulated using MCNPX code to calculate neutron spectrum flux level, core sub-criticality and peaking factor

  10. OpenARC: Extensible OpenACC Compiler Framework for Directive-Based Accelerator Programming Study

    Lee, Seyong [ORNL; Vetter, Jeffrey S [ORNL

    2014-01-01

    Directive-based, accelerator programming models such as OpenACC have arisen as an alternative solution to program emerging Scalable Heterogeneous Computing (SHC) platforms. However, the increased complexity in the SHC systems incurs several challenges in terms of portability and productivity. This paper presents an open-sourced OpenACC compiler, called OpenARC, which serves as an extensible research framework to address those issues in the directive-based accelerator programming. This paper explains important design strategies and key compiler transformation techniques needed to implement the reference OpenACC compiler. Moreover, this paper demonstrates the efficacy of OpenARC as a research framework for directive-based programming study, by proposing and implementing OpenACC extensions in the OpenARC framework to 1) support hybrid programming of the unified memory and separate memory and 2) exploit architecture-specific features in an abstract manner. Porting thirteen standard OpenACC programs and three extended OpenACC programs to CUDA GPUs shows that OpenARC performs similarly to a commercial OpenACC compiler, while it serves as a high-level research framework.

  11. Effect of dietary, social, and lifestyle determinants of accelerated aging and its common clinical presentation: A survey study

    Samarakoon, S. M. S.; Chandola, H. M.; Ravishankar, B.

    2011-01-01

    Aging is unavoidable and natural phenomenon of life. Modern gerontologists are realizing the fact that aging is a disease, which Ayurveda had accepted as natural disease since long. Rate of aging is determined by one's biological, social, lifestyle, and psychological conditions and adversity of which leads to accelerated form of aging (Akalaja jara or premature aging). The aim of this study is to identify potential factors that may accelerate aging in the context of dietry factors, lifestyle ...

  12. Accelerated characterization for long-term creep behavior of polymer

    Zhao, Rongguo; Chen, Chaozhong; Li, Qifu; Luo, Xiyan

    2008-11-01

    Based on the observation that high stress results in increasing creep rate of polymeric material, which is analogous to the time-temperature equivalence, where high temperature accelerates the process of creep or relaxation of polymer, the time-stress equivalence is investigated. The changes of intrinsic time in polymer induced by temperature and stress are studied using the free volume theory, and a clock model based on the time-temperature and time-stress equivalence is constructed to predict the long-term creep behavior of polymer. Polypropylene is used for this work. The specimens with shape of dumbbell are formed via injection molding. The short-term creep tests under various stress levels are carried out at ambient temperature. The creep strains of specimens are modeled according to the concept of time-stress equivalence, and the corresponding stress shift factors are calculated. A master creep curve is built by the clock model. The result indicates that the time-stress superposition principle provides an accelerated characterization method in the laboratory. Finally, the time-dependent axial elongations at sustained stress levels, whose values are close to the tensile strength of polypropylene, are measured. The three phases of creep, i.e., the transient, steady state and accelerated creep phases, are studied, and the application and limitation of the time-stress superposition principle are discussed.

  13. Chronic unpredictable stress (CUS) enhances the carcinogenic potential of 7,12-dimethylbenz(a)anthracene (DMBA) and accelerates the onset of tumor development in Swiss albino mice.

    Suhail, Nida; Bilal, Nayeem; Hasan, Shirin; Ahmad, Ausaf; Ashraf, Ghulam Md; Banu, Naheed

    2015-11-01

    Social stressors evolving from individual and population interactions produce stress reactions in many organisms (including humans), influencing homeostasis, altering the activity of the immunological system, and thus leading to various pathological states including cancer and their progression. The present study sought to validate the effectiveness of chronic unpredictable stress (CUS) in cancer promotion and to assess oxidative stress outcomes in terms of various in vivo biochemical parameters, oxidative stress markers, DNA damage, and the development of skin tumors in Swiss albino mice. Animals were randomized into different groups based on their exposure to CUS alone, 7,12-dimethylbenz(a)anthracene (DMBA) alone (topical), and DMBA-12-O-tetradecanoylphorbol-13-acetate (TPA) (topical) and exposure to CUS prior to DMBA or DMBA-TPA treatments and sacrificed after 16 weeks of treatment. Prior exposure to CUS significantly increased the pro-oxidant effect of carcinogen, depicted by compromised levels of antioxidants in the circulation and skin, accompanied by enhanced lipid peroxidation, plasma corticosterone, and marker enzymes as compared to DMBA-alone or DMBA-TPA treatments. DNA damage results corroborated the above biochemical outcomes. Also, the development of skin tumors (in terms of their incidence, tumor yield, and tumor burden) in mice in the presence and absence of stress further strongly supported our above biochemical measurements. CUS may work as a promoter of carcinogenesis by enhancing the pro-oxidant potential of carcinogens. Further studies may be aimed at the development of interventions for disease prevention by identifying the relations between psychological factors and DNA damage. PMID:26272695

  14. HVEM-ion accelerator facility with its application to fundamental studies on nuclear materials

    High voltage electron microscopy combined with an ion accelerator, analytical electron microscopy and high resolution electron microscopy have been used for in-situ observation of radiation-induced phenomena in alloys and ceramics. Systematic experiments and their analyses have led to an understanding of the fundamental aspects of radiation effects in metallic, ionic and covalent crystals. The present paper reviews the progress of our studies on induced phenomena in alloys and ceramics under irradiation with electrons and/or ions. Particular emphasis is placed on the mechanisms of radiation-induced phenomena, such as defect aggregation, chemical disordering, precipitation, spinodal decomposition and amorphization. This paper also shows a trend of our studies on the synergistic effect of dual-beam irradiation with ions and electrons which is extremely important for designing nuclear materials. (author)

  15. A two-accelerator facility and its use for radiation damage studies in alkali halides

    An experimental system is described in which heavy ions, of energies 50-100 MeV, and light ions of energies 0.5-2 MeV, may be transported alternately from different accelerators into a common scattering chamber. The beam-transport and scattering-chamber details are described, the latter being designed to make in-beam studies of different modes of radiation damage in the target material. Experimental studies are described of simultaneous detection of back-scattered helium ions, X-rays and optical absorption in single-crystal alkali halide samples, done during continuous irradiation by a 1 MeV He beam; also back-scattered protons following intermittent irradiation by a 60 MeV oxygen beam. Analysis of the relative damage by these two beams is discussed in relation to a damage mechanism due to Pooley

  16. Decay kinetics of nicotine/NNK-DNA adducts in vivo studied by accelerator mass spectrometry

    The decay kinetics of nicotine-DNA adducts and NNK-DNA adducts in mice liver after single dosing was studied by accelerator mass spectrometry (AMS). The decay is characterized by a two-stage process. The half-lives of nicotine-DNA adducts are 1.3 d (4-24 h) and 7.0 d (1-21 d), while for NNK-DNA adducts are 0.7 d (4-24 h) and 18.0 d (1-21 d). The relatively faster decay of nicotine-DNA adducts suggests that the genotoxicity of nicotine is weaker than that of NNK. The in vitro study shows that the metabolization of nicotine is necessary for the final formation of nicotine-DNA adducts, and nicotine Δ1'(5') iminium ion is a probable metabolite species that binds to DNA molecule covalently

  17. Enhancing sample preparation capabilities for accelerator mass spectrometry radiocarbon and radiocalcium studies

    With support provided by the LLNL Accelerator Mass Spectrometry Laboratory, the UCR Radiocarbon Laboratory continued its studies involving sample pretreatment and target preparation for both AMS radiocarbon (14C) and radiocalcium (41Ca) involving applications to archaeologically -- and paleoanthropologically- related samples. With regard to AMS 14C-related studies, we have extended the development of a series of procedures which have, as their initial goal, the capability to combust several hundred microgram amounts of a chemically-pretreated organic sample and convert the resultant CO2 to graphitic carbon which will consistently yield relatively high 13C- ion currents and blanks which will yield, on a consistent basis, 14C count rates at or below 0.20% modern, giving an 2 sigma age limit of >50,000 yr BP

  18. An empirical study on managing stress in guided schools to increase educational skills

    Leila Zeinalian

    2012-01-01

    The primary objective of this paper is to study the impact of stress on educational school- children who are enrolled in guided schools. Teenagers are normally facing with stress and feelings and when the level of stress increases, they may face with problems, which would become more serious as they get older. In this study, we perform a standard stress relief program (CS-R Coping With Stress-Revised) and try to reduce the burden of stress among 1240 students who attended guided schools. We s...

  19. What characterizes persons with high levels of perceived stress in Denmark? A national representative study

    Nielsen, Line; Curtis, Tine; Kristensen, Tage S;

    2008-01-01

    with high levels of stress by factors measured at both the individual and neighbourhood levels in a national representative sample of the Danish population. METHODS: The 10,022 participants in the National Health Interview Survey 2005 were asked about perceived stress and individual factors in a cross...... perceived stress is characterized by individual and neighbourhood factors with negative impacts on quality of life and risk of illness. This knowledge can guide future stress prevention efforts. Additionally, the results suggest a negative social component where perceived stress, unhealthy lifestyle and low......AIMS: Stress is a growing public health problem, but there are only a few studies with national representative samples on the occurrence of stress. The aim of this study was to assess the level of stress, measured by the Perceived Stress Scale, in Denmark, and to identify and characterize the group...

  20. Can Accelerators Accelerate Learning?

    The 'Young Talented' education program developed by the Brazilian State Funding Agency (FAPERJ)[1] makes it possible for high-schools students from public high schools to perform activities in scientific laboratories. In the Atomic and Molecular Physics Laboratory at Federal University of Rio de Janeiro (UFRJ), the students are confronted with modern research tools like the 1.7 MV ion accelerator. Being a user-friendly machine, the accelerator is easily manageable by the students, who can perform simple hands-on activities, stimulating interest in physics, and getting the students close to modern laboratory techniques.

  1. Diethyl Phthalate Causes Oxidative Stress: An in Vitro Study

    Heena Prajapati

    2014-03-01

    Full Text Available Background: Phthalates are a group of multifunctional chemicals. Diethyl phthalate (DEP is one of the most frequently used phthalates in solvents and fixatives for numerous industrial products. Method: The present experiment was designed to assess oxidative stress, if any, caused by diethyl phthalate. For this the homogenates of liver and kidney were treated with different concentrations ( 10-40 µg/mL of DEP. 10% liver and kidney homogenates were prepared in phosphate buffered saline and used for estimation of lipid peroxidation.In final step lipid peroxidation and total protein content were analyzed. Results: The result revealed significant and dose - dependent increase in lipid peroxidation, whereas protein content reduced significantly. Maximum increase in LPO and decrease in protein content was observed at 40 µg/mL of DEP concentration. Conclusion: From this study, it can be concluded that different concentrations of DEP leads to dose- dependent significant increase in lipid peroxidation and decrease protein content.So at the different concentration of DEP cause oxidative stress.

  2. Endovascular Treatment of Thoracic Aortic Dissection: Hemodynamic Shear Stress Study

    Tang, Yik Sau; Lai, Siu Kai; Cheng, Stephen Wing Keung; Chow, Kwok Wing

    2012-11-01

    Thoracic Aortic Dissection (TAD), a life threatening cardiovascular disease, occurs when blood intrudes into the layers of the aortic wall, creating a new artificial channel (the false lumen) beside the original true lumen. The weakened false lumen wall may expand, enhancing the risk of rupture and resulting in high mortality. Endovascular treatment involves the deployment of a stent graft into the aorta, thus blocking blood from entering the false lumen. Due to the irregular geometry of the aorta, the stent graft, however, may fail to conform to the vessel curvature, and would create a ``bird-beak'' configuration, a wedge-shaped domain between the graft and the vessel wall. Computational fluid dynamics analysis is employed to study the hemodynamics of this pathological condition. With the `beaking' configuration, the local hemodynamic shear stress will drop below the threshold of safety reported earlier in the literature. The oscillating behavior of the shear stress might lead to local inflammation, atherosclerosis and other undesirable consequences. Supported by the Innovation and Technology Fund of the Hong Kong Government.

  3. Chronic pain, perceived stress, and cellular aging: an exploratory study

    Sibille Kimberly T

    2012-02-01

    Full Text Available Abstract Background Chronic pain conditions are characterized by significant individual variability complicating the identification of pathophysiological markers. Leukocyte telomere length (TL, a measure of cellular aging, is associated with age-related disease onset, psychosocial stress, and health-related functional decline. Psychosocial stress has been associated with the onset of chronic pain and chronic pain is experienced as a physical and psychosocial stressor. However, the utility of TL as a biological marker reflecting the burden of chronic pain and psychosocial stress has not yet been explored. Findings The relationship between chronic pain, stress, and TL was analyzed in 36 ethnically diverse, older adults, half of whom reported no chronic pain and the other half had chronic knee osteoarthritis (OA pain. Subjects completed a physical exam, radiographs, health history, and psychosocial questionnaires. Blood samples were collected and TL was measured by quantitative polymerase chain reaction (qPCR. Four groups were identified characterized by pain status and the Perceived Stress Scale scores: 1 no pain/low stress, 2 no pain/high stress, chronic pain/low stress, and 4 chronic pain/high stress. TL differed between the pain/stress groups (p = 0.01, controlling for relevant covariates. Specifically, the chronic pain/high stress group had significantly shorter TL compared to the no pain/low stress group. Age was negatively correlated with TL, particularly in the chronic pain/high stress group (p = 0.03. Conclusions Although preliminary in nature and based on a modest sample size, these findings indicate that cellular aging may be more pronounced in older adults experiencing high levels of perceived stress and chronic pain.

  4. Study to evaluate the effectiveness of stress management workshops on response to general and occupational measures of stress.

    Heron, R J; McKeown, S; Tomenson, J A; Teasdale, E L

    1999-09-01

    This study was designed to evaluate the effectiveness of stress management training workshops within Zeneca Pharmaceuticals. The study was of cross-sectional design, comparing groups of workshop attendees and non-attendees. In addition, self-rated well-being scores of attendees were compared with results obtained pre-workshop and 2-3 months after the workshop. Employees participating in the study were drawn from the Manufacturing, Research and Development, Sales and Marketing sites of Zeneca Pharmaceuticals located in Cheshire, United Kingdom. Three hundred and ninety persons who had participated in stress management workshops since 1988 were matched for age, gender and department with an equal number of employees who had not attended stress management workshops. Outcome measures included self-rated well-being (as measured by the 30-question General Health Questionnaire), knowledge of company guidance on the management of stress in staff, and an assessment of coping strategies. Subjects who had not attended a stress management workshop were much more likely to have a poor understanding of the principles of management of stress in staff [odds ratio (OR) = 8.3; 95% confidence interval (CI) = 3.3-21.3] and more likely to have poor coping skills (OR = 2.8; CI = 1.3-6.1). However, mean scores for the two measures were similar in attendees and non-attendees. Self-rating of current well-being was strongly associated with the life-events score, but not related to workshop attendance. The study indicates that stress management training workshops reduce the prevalence of employees with a poor understanding of the principles of the management of stress in staff and with poor coping strategies. An improvement in the self-rated well-being observed shortly after the workshop was not sustained. PMID:10665148

  5. Social support, coping, life events, and posttraumatic stress symptoms among former peacekeepers: a prospective study.

    Dirkzwager, A.J.E.; Bramsen, I.; Ploeg, H.M. van der

    2003-01-01

    This study examined both cross-sectionally and longitudinally the relationship between social support, coping strategies, additional stressful life events, and symptoms of posttraumatic stress disorder (PTSD) among Dutch former peacekeeping soldiers. Two groups of peacekeepers were investigated: 311

  6. Studies on high-precision machining of accelerator disks of X-band structure for a linear collider

    One of the critical requirements for the accelerating structures of the main linacs for a linear collider is the precise control of the distributions of the accelerating and higher order mode frequencies. This paper describes major challenges in the fabrication of disks for such accelerating structures. We have studied the issues associated with high-precision machining of copper disks that are used for the Detuned Structure(DS), Damped Detuned Structure(DDS) and Rounded Damped Detuned Structure(RDDS). We have proven that the 3D curved surface of such disks can be machined with a precision of better than ± 1 μm. We have established that the resonant frequencies of the accelerating mode for these copper disks can be controlled within 1 MHz. (author)

  7. Dielectric Laser Acceleration

    England, R. Joel; Noble, Robert J.; Wu, Ziran; Qi, Minghao

    2013-01-01

    We describe recent advances in the study of particle acceleration using dielectric near-field structures driven by infrared lasers, which we refer to as Dielectric Laser Accelerators. Implications for high energy physics and other applications are discussed.

  8. Does recombinant human erythropoietin accelerate correction of post-ulcer-bleeding anaemia? A pilot study

    Spiros D. Ladas; Dimitrios Polymeros; Thomas Pagonis; Konstantinos Triantafyllou; Gregorios Paspatis; Maria Hatziargiriou; Sotirios A.Raptis

    2004-01-01

    AIM: Anaemia caused by acute upper gastrointestinal bleeding is treated with blood transfusion or iron, but patients usually face a two-month recovery period from posthaemorrhage anaemia. This prospective, randomised, open,pilot study was designed to investigate whether recombinant human erythropoietin (Epoetin) therapy accelerate haematocrit increase in the post-bleeding recovery period.METHODS: We studied hospitalised patients admitted because of acute ulcer bleeding or haemorrhagic gastritis,who had a haematocrit of 27-33% and did not receive blood transfusions. One day after the endoscopic confirmation of cessation of bleeding, they were randomised either to erythropoietin (20 000 IU Epoetin alfa subcutaneously, on days 0, 4 and 6) plus iron (100 mg im, on days 1- 6, (G1) or iron only (G2). Haematocrit was measured on days 0, 6, 14,30, 45, and 60, respectively.RESULTS: One patient from G1 and two from G2 were lost to follow-up. Therefore, 14 and 13 patients from G1 and G2respectively were analysed. Demographic characteristics, serum iron, ferritin, total iron binding capacity, reticulocytes, and haematocrit were not significantly different at entry to the study.Median reticulocyte counts were significantly different between groups on day six (G1: 4.0, 3.0-6.4 vsG2: 3.5, 2.1-4.4%,P=0.03) and median haematocrit on day fourteen [G1: 35.9,30.7-41.0 vsG2: 32.5, 29.5-37.0% (median, range), P=0.04].CONCLUSION: Erythropoietin administration significantly accelerates correction of anemia after acute ulcer bleeding.The haematocrit gain is equivalent to one unit of transfused blood two weeks after the bleeding episode.

  9. Stress and health related quality of life of Nepalese students studying in South Korea: A cross sectional study

    Bhandari Pratibha

    2012-03-01

    Full Text Available Abstract Background In recent years there has been a growing trend among students to travel for educational purposes to other countries where there is the possibility of experiencing considerable amounts of stress affecting their physical and mental functioning. The aims of the current study were to investigate the health related quality of life (HRQOL of Nepalese students studying in South Korea to explore the relationship between HRQOL and perceived and acculturative stress, and to identify the determinants of HRQOL. Methods One hundred and thirty students were enrolled in this study. HRQOL was assessed using the Medical Outcomes Study Short Forms (SF-12 questionnaire. Perceived stress and acculturative stress was measured using the Perceived Stress Scale and Acculturative Stress Scale for international students, respectively. Pearson's correlation test and multiple regression analysis were performed. Results Perceived stress and acculturative stress were negatively correlated with HRQOL. The highest value in the HRQOL was reported for the vitality subscale and the lowest value was reported for the role-emotional. In the regression model, perceived stress, acculturative stress, relationship with advisor, and marital status accounted for a significant (p Conclusions The findings of this study indicate that Nepalese students studying in South Korea experience a considerable amount of perceived and acculturative stress, which is negatively related with their HRQOL. Provision of culture specific counseling and orientation programs may benefit the students. The determinants of HRQOL identified in this study were perceived stress, acculturative stress, relationship with advisor, and marital status.

  10. Studies of industrial emissions by accelerator-based techniques: A review of applications at CEDAD

    Calcagnile L.; Quarta G

    2012-01-01

    Different research activities are in progress at the Centre for Dating and Diagnostics (CEDAD), University of Salento, in the field of environmental monitoring by exploiting the potentialities given by the different experimental beam lines implemented on the 3 MV Tande-tron accelerator and dedicated to AMS (Accelerator Mass Spectrome-try) radiocarbon dating and IB A (Ion Beam Analysis). An overview of these activities is presented by showing how accelerator-based analytical techniques can be ...

  11. Accelerator design

    The feasibility of constructing a TeV region electron-positron linear collider in Japan is discussed. The design target of the collider is given as follows: Energy, 1 TeV + 1 TeV; luminosity, 1032-1033/cm2/s; total length, 25km; electric power, 250MW; energy dispersion, 1%-10%; the start of the first experiment, early 1990s. For realizing the above target, the following research and developmental works are necessary. (a) Development of an acceleration tube with short filling time and high shunt resistance. (b) Short pulse microwave source with high peak power. (c) High current, single bunch linac. (d) Beam dynamics. As for the acceleration tube, some possibility is considered: For example, the use of DAW (Disk and Washer) which is being developed for TRISTAN as a traveling-wave tube; and the Jungle Gym-type acceleration tube. As a promising candidate for the microwave source, the Lasertron has been studied. The total cost of the collider construction is estimated to be about 310 billion yen, of which 120 billion yen is for the tunnel and buildings, and 190 billion yen for the accelerator facilities. The operation cost is estimated to be about 3 billion yen per month. (Aoki, K.)

  12. Study on design of superconducting proton linac for accelerator driven subcritical nuclear power system

    Yu Qi; Xu Tao Guang

    2002-01-01

    As a prior option of the next generation of energy source, the accelerator driven subcritical nuclear power system (ADS) can use efficiently the uranium and thorium resource, transmute the high-level long-lived radioactive wastes and raise nuclear safety. The ADS accelerator should provide the proton beam with tens megawatts. The superconducting linac (SCL) is a good selection of ADS accelerator because of its high efficiency and low beam loss rate. It is constitute by a series of the superconducting accelerating cavities. The cavity geometry is determined by means of the electromagnetic field computation. The SCL main parameters are determined by the particle dynamics computation

  13. Study on design of superconducting proton linac for accelerator driven subcritical nuclear power system

    As a prior option of the next generation of energy source, the accelerator driven subcritical nuclear power system (ADS) can use efficiently the uranium and thorium resource, transmute the high-level long-lived radioactive wastes and raise nuclear safety. The ADS accelerator should provide the proton beam with tens megawatts. The superconducting linac (SCL) is a good selection of ADS accelerator because of its high efficiency and low beam loss rate. It is constitute by a series of the superconducting accelerating cavities. The cavity geometry is determined by means of the electromagnetic field computation. The SCL main parameters are determined by the particle dynamics computation

  14. Prevalence of stress in Casablanca medical students: a cross-sectional study

    Ben Loubir, Dalal; Serhier, Zeineb; Diouny, Samir; Battas, Omar; Agoub, Mohamed; Othmani, Mohammed Bennani

    2014-01-01

    Introduction Recently, an important literature data has reported that medical students experience stress more than students in other disciplines. In contrast, there is a significant shortage of the stress impact on the academic performance. The primary purpose of our study was to determine the prevalence of stress among Casablanca Medical students and to investigate if there is an association between stress and academic skills. Methods A total of 275 participants studying at Casablanca Medica...

  15. The process of coping with stress by Taiwanese medical interns: a qualitative study

    Liu, Chun-Hao; Tang, Woung-Ru; Weng, Wei-Hung; Lin, Yu-Hsuan; Chen, Ching-Yen

    2016-01-01

    Background Internship, the transition period from medical student to junior doctor, is highly stressful for interns in the West; however, little is known about the experience of interns in coping with stress in Taiwan. This study aimed to develop a model for coping with stress among Taiwanese interns and to examine the relationship between stress and learning outcomes. Methods For this qualitative study, we used grounded theory methodology with theoretical sampling. We collected data through ...

  16. Review of recent transgenic studies on abiotic stress tolerance and future molecular breeding in potato

    Kikuchi, Akira; Huynh, Huu Duc; Endo, Tsukasa; Watanabe, Kazuo

    2015-01-01

    Global warming has become a major issue within the last decade. Traditional breeding programs for potato have focused on increasing productivity and quality and disease resistance, thus, modern cultivars have limited tolerance of abiotic stresses. The introgression of abiotic stress tolerance into modern cultivars is essential work for the future. Recently, many studies have investigated abiotic stress using transgenic techniques. This manuscript focuses on the study of abiotic stress, in par...

  17. Work Stress and Psychological Consequences in The Workplace: Study on Elementary School Teachers

    Arismunandar Arismunandar; Nuri Emmiyati

    2016-01-01

    There are very limited studies examining the relationships between work stress and psychological consequences of the teachers, especially elementary school teachers. Therefore, the primary purpose of conducting this research is to understand the correlation between teachers work stress, and burnout and job satisfaction. It also aims to understand sources and levels of teachers work stress. The findings of the study showed that there was no correlation between teachers work stress and burnout,...

  18. Acceleration of skin wound healing with tragacanth (Astragalus preparation: an experimental pilot study in rats.

    Ehsan Fayazzadeh

    2014-01-01

    Full Text Available Gum tragacanth is a natural complex mixture of polysaccharides and alkaline minerals extracted from species of Astragalus plant, which is found widely in arid regions of the Middle East. In a pilot experimental study we examined the effects of its topical application on wound healing in ten albino adult male rats. Two similar parasagittal elliptical full-thickness wounds (control vs. test samples were created on the dorsum of each animal. Test group samples were fully covered by a thin layer of gum tragacanth daily. The extent of wound healing was evaluated by planimetric analysis on multiple occasions during the 10-day study period. On the 7th day of the study, the percent of wound closure was significantly higher in gum tragacanth-treated specimens compared to the control samples (87%±2% vs. 70%±4%, P<0.001. The majority of wounds in the test group were completely closed by the 10th day of the study. The difference in wound healing index measured by histological examination on day 10 of the study was also statistically meaningful between the two groups (0.624±0.097 vs. 0.255±0.063, P<0.05. The results of this study clearly showed the useful effects of topical application of gum tragacanth in acceleration of skin wound contraction and healing. More studies are encouraged to identify the implicating agents and precisely understand the mechanism by which they exert their wound healing effects.

  19. Study of Laser Wakefield Accelerators as injectors for Synchrotron light sources

    Hillenbrand, Steffen, E-mail: steffen.hillenbrand@kit.edu [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Organisation européenne pour la Recherche nucléaire (CERN), Geneva (Switzerland); Assmann, Ralph, E-mail: ralph.assmann@desy.de [Organisation européenne pour la Recherche nucléaire (CERN), Geneva (Switzerland); Müller, Anke-Susanne, E-mail: anke-susanne.mueller@kit.edu [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Jansen, Oliver [Heinrich-Heine-University, Düsseldorf (Germany); Judin, Vitali [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Pukhov, Alexander [Heinrich-Heine-University, Düsseldorf (Germany)

    2014-03-11

    Laser WakeField Accelerators (LWFA) feature short bunch lengths and high peak currents, combined with a small facility footprint. This makes them very interesting as injectors for Synchrotron light sources. Using the ANKA Synchrotron as an example, we investigate the possibility to inject a LWFA bunch into an electron storage ring. Particular emphasis is put on the longitudinal evolution of the bunch. - Highlights: • Short electron bunches are very interesting for the generation of Synchrotron radiation. • LWFA have therefore been studied as injectors for ring-based light sources. • It was shown that preserving their initial bunch length is very challenging. • Bunch density evolution could still lead to interesting radiation properties.

  20. Studies of the chromatic properties and dynamic aperture of the BNL colliding-beam accelerator

    The PATRICIA particle tracking program has been used to study chromatic effects in the Brookhaven CBA (Colliding Beam Accelerator). The short term behavior of particles in the CBA has been followed for particle histories of 300 turns. Contributions from magnet multipoles characteristic of superconducting magnets and closed orbit errors have been included in determining the dynamic aperture of the CBA for on and off momentum particles. The width of the third integer stopband produced by the temperature dependence of magnetization induced sextupoles in the CBA cable dipoles is evaluated for helium distribution systems having periodicity of one and six. The stopband width at a tune of 68/3 is naturally zero for the system having a periodicity of six and is approx. 10-4 for the system having a periodicity of one. Results from theory are compared with results obtained with PATRICIA; the results agree within a factor of slightly more than two

  1. Study of electron acceleration through the ? mode in a collisional plasma-filled cylindrical waveguide

    Abdoli-Arani, A.; Moghaddasi, M.

    2016-07-01

    Acceleration of an externally injected electron inside the collisional plasma-filled cylindrical waveguide during its motion in the fields of the ? mode excited by microwave radiation is studied. The effect of the electron collision frequency with background ions on the deflection angle and energy gain of electron, when it is injected along the direction of the mode propagation is investigated. The fields for the mode, the deflection angle of electron trajectory, due to these fields, and the electron energy gradient are obtained. The results for collisionless and collisional plasma are graphically presented. The numerical results illustrate that the presence of the electron collision term in the dielectric permittivity can reduce the electron's energy gain in the configuration.

  2. Study of muon-induced neutron production using accelerator muon beam at CERN

    Cosmogenic muon-induced neutrons are one of the most problematic backgrounds for various underground experiments for rare event searches. In order to accurately understand such backgrounds, experimental data with high-statistics and well-controlled systematics is essential. We performed a test experiment to measure muon-induced neutron production yield and energy spectrum using a high-energy accelerator muon beam at CERN. We successfully observed neutrons from 160 GeV/c muon interaction on lead, and measured kinetic energy distributions for various production angles. Works towards evaluation of absolute neutron production yield is underway. This work also demonstrates that the setup is feasible for a future large-scale experiment for more comprehensive study of muon-induced neutron production

  3. Degradation study of trichloroethylene and perchloric ethylene using high energy electron beam generated in industrial accelerator

    The pollution of potable water with chlorinated hydrocarbons, mainly trichloroethylene (TCE) and perchloric ethylene (PCE), is seriously increasing the problem of contamination of water, specially in highly industrialized areas. Recent studies show that depuration by ionizing radiation has been considered a possible alternative to the control of water pollution, wherein the process by ionizing radiation converts TCE and PCE into approximately 100% carbon dioxide ions. Water samples containing TCE e PCE were submitted to radiation in the pilot plant installed in the industrial electron accelerator at IPEN from Radiation Dynamics, Dynamitron II, of 1,5 MeV - 25 m A, with doses varying from 2 kGy to 8 kGy, being its parameters analyzed before and after irradiation TCE and PCE concentrations were determined by the gas chromatography method by liquid-liquid extraction using a gas chromatograph, model CG 90, with an electron capture detector. (author). 5 refs, 4 figs

  4. Development of a linear electromagnetic accelerator (Rail Gun) for impact fusion and related studies

    In order to further enhance the capability of our railgun system, we have developed a 50 cm long; 6 mm square bore railgun accelerating 0.3 g nylon projectiles to 3.1 km/s. Improvements have been carried out in the rail gun design and current source configuration. A simple electrical schematic of the gun is drawn with PSpice 9.2 schematic, which can simulate the electrical pulse that takes place when the driving capacitor bank discharges through the rail gun system and the results obtained are used to predict the performance of the rail gun before actual firing. These series of railgun development have been carried out in the context of our program related to experimental studies of Impact Fusion. (author)

  5. Focusing studies of an applied Br extraction diode on the LION accelerator

    The LION Accelerator, 1.5 MV, 4 Ω, is being used to study the characteristics of an applied Br extraction diode. The diode utilizes both an inner and outer cathode and has been observed to operate at high ion current efficiencies compared to previous extraction diodes. Typical efficiencies were measured to be ∼80% which compares very favorably with the efficiencies seen in applied Bz diodes. In this paper, the authors report the results of a series of experiments examining the role of the inner cathode in electron loss and ion emission. In addition, operation with an argon gas cell is reported. The ion beam appears to be space-charge neutralized by the gas cell foil alone, and current neutralized when the gas cell pressure is above 100 mT

  6. Simulation study of accelerator based quasi-mono-energetic epithermal neutron beams for BNCT.

    Adib, M; Habib, N; Bashter, I I; El-Mesiry, M S; Mansy, M S

    2016-01-01

    Filtered neutron techniques were applied to produce quasi-mono-energetic neutron beams in the energy range of 1.5-7.5 keV at the accelerator port using the generated neutron spectrum from a Li (p, n) Be reaction. A simulation study was performed to characterize the filter components and transmitted beam lines. The feature of the filtered beams is detailed in terms of optimal thickness of the primary and additive components. A computer code named "QMNB-AS" was developed to carry out the required calculations. The filtered neutron beams had high purity and intensity with low contamination from the accompanying thermal, fast neutrons and γ-rays. PMID:26474209

  7. Studies of the chromatic properties and dynamic aperture of the BNL colliding beam accelerator

    The PATRICIA particle tracking program has been used to study chromatic effects in the Brookhaven CBA (Colliding Beam Accelerator). The short term behavior of particles in the CBA has been followed for particle histories of 300 turns. Contributions from magnet multipoles characteristic of superconducting magnets and closed orbit errors have been included in determining the dynamic aperture of the CBA for on and off momentum particles. The width of the third integer stopband produced by the temperature dependence of magnetization induced sextupoles in the CBA cable dipoles is evaluated for helium distribution systems having periodicity of one and six. The stopband width at a tune of 68/3 is naturally zero for the system having a periodicity of six and is ∫10-4 for the system having a periodicity of one. Results from theory are compared with results obtained with PATRICIA; the results agree within a factor of slightly more than two

  8. The relationships between the use of self-regulated learning strategies and depression among medical students: an accelerated prospective cohort study.

    Van Nguyen, Hung; Laohasiriwong, Wongsa; Saengsuwan, Jiamjit; Thinkhamrop, Bandit; Wright, Pamela

    2015-01-01

    We conducted this study to determine the relationships between the use of self-regulated learning strategies (SRL) and depression scores among medical students. An accelerated prospective cohort study among 623 students at a public medical university in Vietnam was carried out during the academic year 2012-2013. The Depression, Anxiety and Stress Scales (21 items) was used to measure depression scores as the primary research outcome, and to measure anxiety and stress scores as the confounding variables. Fourteen SRL subscales including intrinsic/extrinsic goal orientation, task value, self-efficacy for learning, control of learning beliefs, rehearsal, elaboration, organization, critical thinking, meta-cognitive strategies, time and study environment, effort regulation, peer learning, and help seeking were measured using the Motivated Strategies for Learning Questionnaire. Data were collected at two points in time (once each semester). There were 744 responses at the first time (95.88%) and 623 at time two (drop-out rate of 16.26%). The generalized estimating equation was applied to identify any relationships between the use of each SRL subscale and depression scores at time 2, adjusting for the effects of depression at time 1, anxiety, stress, within cluster correlation, and potential demographic covariates. Separate multivariate GEE analysis indicated that all SRL subscales were significantly negatively associated with depression scores, except for extrinsic goal orientation and peer learning. Whereas full multivariate GEE analysis revealed that self-efficacyT1, help-seekingT1, time and study environmentT2 were found to be significantly negatively associated with depressionT2, adjusting for the effects of depressionT1, anxiety, stress, and demographic covariates. The results should be used to provide appropriate support for medical students to reduce depression. PMID:24628063

  9. Preliminary studies of a new accelerator-driven minor actinide burner in industrial scale

    Highlights: • A new accelerator-driven minor actinide (MA) burner was proposed. • Comprehensive design of spallation target, fuel assembly and subcritical core was performed. • Preliminary safety analyses indicate the inherent safety of the core in the reactivity insertion (500 pcm) and beam overpower (50% increase) transients. - Abstract: Pursuing high transmutation rate of minor actinide (MA), a preliminary conceptual design of a lead-bismuth (LBE) cooled accelerator-driven system (ADS) is proposed in this study. Parametric studies are performed to optimize the neutronics and thermal–hydraulics performances. The proton energy and axial position of the proton beam impact is investigated to obtain high neutron source efficiency and spallation neutron yield. The influences of MA/Pu mixing ratio and the ratio of pin pitch to diameter (P/D) are also optimized to control the burnup reactivity swing and the minimum coolant velocity for adequate cooling. To reduce the power peak, three kinds of power flattening techniques are adopted and compared. The results show that the inert matrix ratio zone loading method seems more versatile. Based on the analyses, an optimized three zone loading pattern is proposed for the 800 MWth subcritical core. The total transmutation rate of MA is 328.8 kg per effective full power year. Preliminary safety analyses based on the balance of power method (BOP) are performed and the results show that in the reactivity insertion and beam overpower transients, the core shows inherent safety, but the scram is necessary by cutting off the beam current to protect the core from possible damages caused by the loss of flow

  10. Preliminary studies of a new accelerator-driven minor actinide burner in industrial scale

    Li, Xunzhao; Zhou, Shengcheng [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi (China); Zheng, Youqi, E-mail: yqzheng@mail.xjtu.edu.cn [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi (China); Wang, Kunpeng [Nuclear and Radiation Safety Center, PO Box 8088, No. 54, Beijing 100082 (China); Wu, Hongchun [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi (China)

    2015-10-15

    Highlights: • A new accelerator-driven minor actinide (MA) burner was proposed. • Comprehensive design of spallation target, fuel assembly and subcritical core was performed. • Preliminary safety analyses indicate the inherent safety of the core in the reactivity insertion (500 pcm) and beam overpower (50% increase) transients. - Abstract: Pursuing high transmutation rate of minor actinide (MA), a preliminary conceptual design of a lead-bismuth (LBE) cooled accelerator-driven system (ADS) is proposed in this study. Parametric studies are performed to optimize the neutronics and thermal–hydraulics performances. The proton energy and axial position of the proton beam impact is investigated to obtain high neutron source efficiency and spallation neutron yield. The influences of MA/Pu mixing ratio and the ratio of pin pitch to diameter (P/D) are also optimized to control the burnup reactivity swing and the minimum coolant velocity for adequate cooling. To reduce the power peak, three kinds of power flattening techniques are adopted and compared. The results show that the inert matrix ratio zone loading method seems more versatile. Based on the analyses, an optimized three zone loading pattern is proposed for the 800 MWth subcritical core. The total transmutation rate of MA is 328.8 kg per effective full power year. Preliminary safety analyses based on the balance of power method (BOP) are performed and the results show that in the reactivity insertion and beam overpower transients, the core shows inherent safety, but the scram is necessary by cutting off the beam current to protect the core from possible damages caused by the loss of flow.

  11. Secondary traumatic stress and vicarious trauma: a validational study.

    Jenkins, Sharon Rae; Baird, Stephanie

    2002-10-01

    Vicarious trauma (VT) and secondary traumatic stress (STS) or compassion fatigue both describe effects of working with traumatized persons on therapists. Despite conceptual similarities, their emphases differ: cognitive schemas vs. posttraumatic symptoms and burnout, respectively. The TSI Belief Scale (TSI-BSL) measures VT; the Compassion Fatigue Self-Test (CFST) for Psychotherapists measures STS. Neither has substantial psychometric evidence yet, nor has their association been studied. Results for 99 sexual assault and domestic violence counselors show concurrent validity between TSI-BSL and CFST, moderate convergence with burnout but useful discrimination, and strong convergence with general distress, but adequate independent shared variance. Counselors with interpersonal trauma histories scored higher on CFST, but not TSI-BSL or burnout, consistent with the CFST's emphasis on trauma symptomatology. PMID:12392231

  12. Laboratory stress corrosion cracking studies with sulfur acids and chlorides

    Baylor, V.B.

    1985-10-01

    Stress corrosion cracking (SCC) caused by polythionic acid and/or chlorides has occurred in coal liquefaction pilot plants. This problem is also common in refineries and has been extensively researched. This study examines: (1) the relationship of the ASTM standard ferric sulfate-sulfuric acid test for determining sensitization to resistance to polythionic SCC; (2) the cracking resistance of higher-alloy. Fe-Ni-Cr materials and common austenitic stainless steels (SS); and (3) the effect of chloride concentrations up to 1% in polythionic acid solutions on cracking behavior. The ferric sulfatesulfuric acid test can be used as an acceptance test for materials resistant to polythionic acid SCC. More highly alloyed materials were more resistant to sensitization than most austenitic SS and were virtually unattacked in polythionic acid solutions containing up to 1% chloride. Chloride increased the corrosion rate and caused localized pitting but it did not significantly affect the number of failures or the failure mode.

  13. Biological studies of post-traumatic stress disorder.

    Pitman, Roger K; Rasmusson, Ann M; Koenen, Karestan C; Shin, Lisa M; Orr, Scott P; Gilbertson, Mark W; Milad, Mohammed R; Liberzon, Israel

    2012-11-01

    Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is considered to be known: that is, an event that involves threat to the physical integrity of oneself or others and induces a response of intense fear, helplessness or horror. Although PTSD is still largely regarded as a psychological phenomenon, over the past three decades the growth of the biological PTSD literature has been explosive, and thousands of references now exist. Ultimately, the impact of an environmental event, such as a psychological trauma, must be understood at organic, cellular and molecular levels. This Review attempts to present the current state of this understanding on the basis of psychophysiological, structural and functional neuroimaging, and endocrinological, genetic and molecular biological studies in humans and in animal models. PMID:23047775

  14. The Effect of Gender on Stress Factors: An Exploratory Study among University Students

    Michelle Calvarese

    2015-11-01

    Full Text Available This study examined the relationship between gender and reactions to stress among university students. University students were surveyed on how they typically responded when under perceived stress. There were significant differences between males and females concerning their reactions to stress. Overall, more females experienced higher levels of depression, frustration, and anxiety than their male counterparts when reacting to stress. Males also tended to have other psychological reactions different from those listed on the survey. In addition, while the stress reaction of anger was barely statistically insignificant, more females expressed anger than males as a reaction to stress.

  15. A Comparative Study of Stressful Life Events and Stress Coping Strategies in Coronary Heart Disease Patients and Non-Patients

    A. Heidari Pahlavian

    2010-10-01

    Full Text Available Introduction & Objective: Etiological researches suggest that biopsychosocial dimensions are responsible for coronary heart disease (CHD. The main goal of the present research was to compare stressful life events and stress coping strategies in coronary heart patients (Acute Myocardial Infarction and non-patients. Materials & Methods: In this cross sectional research 102 patients (all males suffering from acute myocardial infarction and 162 non-patient individuals after matching were studied and compared with regard to psychosocial life events and stress coping strategies through coping response inventory (Moos, 1993 , scaling of life Events (paykel , 1971 and researcher made questionnaire. Results: The result established that myocardial infarction patients experienced more stress than the control group during one year before heart- attack and they used more inadequate stress coping strategies comparing with the control individuals. Conclusion: This study showed that stress and inadequate coping strategies are important variables for the development of coronary heart diseases. (Sci J Hamadan Univ Med Sci 2010;17(3:33-38

  16. Perceived Stress Scale: Reliability and Validity Study in Greece

    Eleni Andreou; Alexopoulos, Evangelos C; Christos Lionis; Liza Varvogli; Charalambos Gnardellis; Chrousos, George P.; Christina Darviri

    2011-01-01

    Objective: To translate the Perceived Stress Scale (versions PSS-4, -10 and -14) and to assess its psychometric properties in a sample of general Greek population. Methods: 941 individuals completed anonymously questionnaires comprising of PSS, the Depression Anxiety and Stress scale (DASS-21 version), and a list of stress-related symptoms. Psychometric properties of PSS were investigated by confirmatory factor analysis (construct validity), Cronbach’s alpha (reliability), and by investigatin...

  17. Linear Accelerators

    Vretenar, M

    2014-01-01

    The main features of radio-frequency linear accelerators are introduced, reviewing the different types of accelerating structures and presenting the main characteristics aspects of linac beam dynamics.

  18. A multi-satellite study of accelerated ionospheric ion beams above the polar cap

    R. Maggiolo

    2006-07-01

    Full Text Available This paper presents a study of nearly field-aligned outflowing ion beams observed on the Cluster satellites over the polar cap. Data are taken at geocentric radial distances of the order of 5–9 RE. The distinction is made between ion beams originating from the polar cusp/cleft and beams accelerated almost along the magnetic field line passing by the spacecraft. Polar cusp beams are characterized by nearly field-aligned proton and oxygen ions with an energy ratio EO+ / EH+, of the order of 3 to 4, due to the ion energy repartition inside the source and to the latitudinal extension of the source. Rapid variations in the outflowing ion energy are linked with pulses/modifications of the convection electric field. Cluster data allow one to show that these perturbations of the convection velocity and the associated ion structures propagate at the convection velocity.

    In contrast, polar cap local ion beams are characterized by field-aligned proton and oxygen ions with similar energies. These beams show the typical inverted V structures usually observed in the auroral zone and are associated with a quasi-static converging electric field indicative of a field-aligned electric field. The field-aligned potential drop fits well the ion energy profile. The simultaneous observation of precipitating electrons and upflowing ions of similar energies at the Cluster orbit indicates that the spacecraft are crossing the mid-altitude part of the acceleration region. In the polar cap, the parallel electric field can thus extend to altitudes higher than 5 Earth radii. A detailed analysis of the distribution functions shows that the ions are heated during their parallel acceleration and that energy is exchanged between H+ and O+. Furthermore, intense electrostatic waves are observed simultaneously. These observations could be due to an ion-ion two-stream instability.

  19. Advanced accelerators

    This report discusses the suitability of four novel particle acceleration technologies for multi-TeV particle physics machines: laser driven linear accelerators (linac), plasma beat-wave devices, plasma wakefield devices, and switched power and cavity wakefield linacs. The report begins with the derivation of beam parameters practical for multi-TeV devices. Electromagnetic field breakdown of materials is reviewed. The two-beam accelerator scheme for using a free electron laser as the driver is discussed. The options recommended and the conclusions reached reflect the importance of cost. We recommend that more effort be invested in achieving a self-consistent range of TeV accelerator design parameters. Beat-wave devices have promise for 1-100 GeV applications and, while not directly scalable to TeV designs, the current generation of ideas are encouraging for the TeV regime. In particular, surfatrons, finite-angle optical mixing devices, plasma grating accelerator, and the Raman forward cascade schemes all deserve more complete analysis. The exploitation of standard linac geometry operated in an unconventional mode is in a phase of rapid evolution. While conceptual projects abound, there are no complete designs. We recommend that a fraction of sponsored research be devoted to this approach. Wakefield devices offer a great deal of potential; trades among their benefits and constraints are derived and discussed herein. The study of field limitation processes has received inadequate attention; this limits experiment designers. The costs of future experiments are such that investment in understanding these processes is prudent. 34 refs., 12 figs., 3 tabs

  20. The importance of physical activity and sleep for affect on stressful days: Two intensive longitudinal studies.

    Flueckiger, Lavinia; Lieb, Roselind; Meyer, Andrea H; Witthauer, Cornelia; Mata, Jutta

    2016-06-01

    We investigated the potential stress-buffering effect of 3 health behaviors-physical activity, sleep quality, and snacking-on affect in the context of everyday life in young adults. In 2 intensive longitudinal studies with up to 65 assessment days over an entire academic year, students (Study 1, N = 292; Study 2, N = 304) reported stress intensity, sleep quality, physical activity, snacking, and positive and negative affect. Data were analyzed using multilevel regression analyses. Stress and positive affect were negatively associated; stress and negative affect were positively associated. The more physically active than usual a person was on a given day, the weaker the association between stress and positive affect (Study 1) and negative affect (Studies 1 and 2). The better than usual a person's sleep quality had been during the previous night, the weaker the association between stress and positive affect (Studies 1 and 2) and negative affect (Study 2). The association between daily stress and positive or negative affect did not differ as a function of daily snacking (Studies 1 and 2). On stressful days, increasing physical activity or ensuring high sleep quality may buffer adverse effects of stress on affect in young adults. These findings suggest potential targets for health-promotion and stress-prevention programs, which could help reduce the negative impact of stress in young adults. (PsycINFO Database Record PMID:26709860

  1. Study of a microwave power source for a two-beam accelerator

    A theoretical and experimental study of a microwave power source suitable for driving a linear e+e- collider is reported. The power source is based on the Relativistic Klystron Two-Beam Accelerator (RK-TBA) concept, is driven by a 5-MeV, 1-kA induction accelerator electron beam, and operates at X-band frequencies. The development of a computer code to simulate the transverse beam dynamics of an intense relativistic electron beam transiting a system of microwave resonant structures is presented. This code is time dependent with self-consistent beam-cavity interactions and uses realistic beam parameters. Simulations performed with this code are compared with analytical theory and experiments. The concept of spacing resonant structures at distances equal to the betatron wavelength of the focusing system to suppress the growth of transverse instabilities is discussed. Simulations include energy spread over the beam to demonstrate the effect of Landau damping and establish the sensitivity of the betatron wavelength spacing scheme to errors in the focusing system. The design of the Reacceleration Experiment is described in detail and includes essentially all the issues related to a full scale RK-TBA microwave source. A total combined power from three output structures in excess of 170 MW with an amplitude stability of ±4% over a 25 ns pulse was achieved. The results of the experiment are compared to simulations used during the design phase to validate the various codes and methods used. The primary issue for the RK-TBA concept is identified as transverse beam instability associated with the excitation of higher order modes in the resonant structures used for extracting microwave power from the modulated beam. This work represents the first successful experimental demonstration of repeated cycles of microwave energy extraction from and reacceleration of a modulated beam

  2. Conceptual study of high power proton linac for accelerator driven subcritical nuclear power system

    Yu Qi; Ouyang Hua Fu; Xu Tao Guang

    2001-01-01

    As a prior option of the next generation of energy source, the accelerator driven subcritical nuclear power system (ADS) can use efficiently the uranium and thorium resource, transmute the high-level long-lived radioactive wastes and raise nuclear safety. The ADS accelerator should provide the proton beam with tens megawatts. The superconducting linac is a good selection of ADS accelerator because of its high efficiency and low beam loss rate. The ADS accelerator presented by the consists of a 5 MeV radio-frequency quadrupole, a 100 MeV independently phased superconducting cavity linac and a 1 GeV elliptical superconducting cavity linac. The accelerating structures and main parameters are determined and the research and development plan is considered

  3. Particle acceleration and plasma energization in substorms: MHD and test particle studies

    Birn, Joachim [Los Alamos National Laboratory

    2015-07-16

    The author organizes his slide presentation under the following topics: background, MHD simulation, orbit integration, typical orbits, spatial and temporal features, acceleration mechanisms, source locations, and source energies. Field-­aligned energetic particle fluxes are shown for 45-keV electrons and 80-keV protons. It is concluded that the onset from local thin current sheet is electron tearing. Acceleration is mainly from field collapse, governed by Ey = -vxXBz: importance of localization; betatron acceleration (similar if nonadiabatic); 1st order Fermi, type B (or A; current sheet acceleration). There are two source regions (of comparable importance in magnetotail): - flanks, inner tail - drift entry - early, higher energy - outer plasma sheet - reconnection entry - later, lower energy. Both thermal and suprathermal sources are important, with limited energy range for acceleration

  4. Intraplaque hemorrhage is associated with higher structural stresses in human atherosclerotic plaques: an in vivo MRI-based 3d fluid-structure interaction study

    Canton Gador

    2010-12-01

    Full Text Available Abstract Background Studies using medical images have shown that intraplaque hemorrhage may accelerate plaque progression and may produce a stimulus for atherosclerosis development by increasing lipid core and plaque volume and creating new destabilizing factors. Image-based 3D computational models with fluid-structure interactions (FSI will be used to perform plaque mechanical analysis and investigate possible associations between intraplaque hemorrhage and both plaque wall stress (PWS and flow shear stress (FSS. Methods In vivo MRI data of carotid plaques from 5 patients with intraplaque hemorrhage confirmed by histology were acquired. 3D multi-component FSI models were constructed for each plaque to obtain mechanical stresses. Plaque Wall Stress (PWS and Flow Shear Stress (FSS were extracted from all nodal points on the lumen surface of each plaque for analysis. Results The mean PWS value from all hemorrhage nodes of the 5 plaques combined was higher than that from non-hemorrhage nodes (75.6 versus 68.1 kPa, P = 0.0003. The mean PWS values from hemorrhage nodes for each of the 5 plaques were all significantly higher (5 out of 5 than those from non-hemorrhage nodes (P 2, P = 0.0002. However, the mean flow shear stress values from individual cases showed mixed results: only one out of five plaques showed mean FSS value from hemorrhage nodes was higher than that from non-hemorrhage nodes; three out of five plaques showed that their mean FSS values from hemorrhage nodes were lower than those from non-hemorrhage nodes; and one plaque showed that the difference had no statistical significance. Conclusion The results of this study suggested that intraplaque hemorrhage nodes were associated with higher plaque wall stresses. Compared to flow shear stress, plaque wall stress has a better correlation with plaque component feature (hemorrhage linked to plaque progression and vulnerability. With further validation, plaque stress analysis may provide

  5. Study on the Resistance of Cucumber to Temperature Stresses

    Ma Dehua; Pang Jin'an; Huo Zhenrong; Li Shuju; Du Shengli

    2000-01-01

    Four cucumber (Cucumis sativus L. ) inbred lines with different resistances to temperature stress were used in this experiment. The seedlings of line Q10 and Q21 that have high resistance to chilling stress also have high resistance to heat stress. The seedlings of line T94 and T55 that have lower resistance to chilling stress also have lower resistance to heat stress. It seems that the resistance of cucumber seedlings to different temperature stresses was similar. The influences of chilling and heat stress on the germination ability of cucumber seeds were different. Under the chilling stress, the germination percentage decreased less, and the germination velocity decreased more,so the germination index decreased significantly. Under the heat stress, the germination percentage and velocity of the seeds with high resistance decreased less and those of the seeds with lower resistance decreased more. The differences among the lines became more evident under the extreme heat condition. The content of chlorophyll decreased under the different temperature stresses, the content of chlorophyll a decreased more than that of chlorophyll b, so the value of chlorophyll a/b decreased.The temperature stress inhibited the photosynthesis of cucumber seedlings significantly. After chilling or heat treatment, the net photosynthetic rate (Pn) decreased remarkably. With the stomatal conductance (Gs) decreased, the stomatal limited value (Is) decreased, the intercellular CO2 concentration (Ci) increased, and both the apparent quantum efficiencies (AQE) and the carboxylation efficiencies (CE) decreased. Results showed that the non-stomatal factors were the main causes of Pn decrease, and the photosynthetic mechanism was destroyed remarkably.

  6. Designing reliability into accelerators

    Future accelerators will have to provide a high degree of reliability. Quality must be designed in right from the beginning and must remain a central theme throughout the project. The problem is similar to the problems facing US industry today, and examples of the successful application of quality engineering will be given. Different aspects of an accelerator project will be addressed: Concept, Design, Motivation, Management Techniques, and Fault Diagnosis. The importance of creating and maintaining a coherent team will be stressed

  7. Understanding Student Stress and Coping in Elementary School: A Mixed-Method, Longitudinal Study

    Sotardi, Valerie A.

    2016-01-01

    This mixed-method, longitudinal study examined daily school stress and coping strategies of elementary schoolchildren in the United States. Students (n = 65) between the ages of 7 and 11 years reported daily school stress measures for 8 weeks and completed individual stress and coping interviews. Results highlight critical relations between…

  8. The Heritability of Hedonic Capacity and Perceived Stress: A Twin Study Evaluation of Candidate Depressive Phenotypes

    Bogdan, Ryan; Pizzagalli, Diego

    2008-01-01

    Background. Anhedonia and stress sensitivity have been identified as promising depressive phenotypes. Research suggests that stress-induced anhedonia is a possible mechanism underlying the association between stress and depression. The present proof-of-concept study assessed whether hedonic capacity and stress perception are heritable and whether their genetic and environmental contributions are shared. Method. Twenty monozygotic (MZ) and 15 dizygotic (DZ) twin pairs completed a probabilistic...

  9. The Influence of Perceived Stress on Cortical Reactivity: A Proof-Of-Principle Study

    Luijcks, Rosan; Vossen, Catherine J.; Hermens, Hermie J.; van Os, Jim; Lousberg, Richel

    2015-01-01

    The aim of this study was to investigate how perceived stress may affect electroencephalographical (EEG) activity in a stress paradigm in a sample of 76 healthy participants. EEG activity was analyzed using multilevel modeling, allowing estimation of nested effects (EEG time segments within subjects). The stress paradigm consisted of a 3-minute pre-stimulus stress period and a 2-minute post-stimulus phase. At t=3 minutes, a single electrical stimulus was delivered. Participants were unaware o...

  10. Stress-Related Symptoms in Swedish Adolescents: A Study in Two Upper Secondary Schools

    Carl Antonson; Frida Thorsén; Kristina Sundquist; Jan Sundquist

    2014-01-01

    Aims: Psychiatric symptoms, sleeping problems and stress are increasing in Swedish adolescents. The aim of this study was to test the hypothesis that a combination of two potential stressors (i.e., high academic proficiency and high urbanicity) in a school setting would be related to increased stress levels and stress-related symptoms among pupils. Our second aim was to evaluate correlations between perceived stress and psychiatric symptoms, sleep quality and personality traits. Methods: 202 ...

  11. Subjective stress reactivity in psoriasis – a cross sectional study of associated psychological traits

    Remröd, Charlotta; Sjöström, Karin; Svensson, Åke

    2015-01-01

    Background Stress or psychological distress is often described as a causative or maintaining factor in psoriasis. Psychological traits may influence the appraisal, interpretation and coping ability regarding stressful situations. Detailed investigations of psychological traits in relation to stress reactivity in psoriasis are rare. The aim of this study was to examine whether patients with psoriasis who report an association between psychological distress and exacerbation, “stress reactors” (...

  12. Stressful Experiences in Children and Adolescents: Initial Report from the PSEI-NCPV Honolulu Study

    Bracha, Dr. Stefan; Ralston, Tyler; Yamashita, Jennifer; Nelson, Gretchen; Lopez, Dr. Hassen H.; Cummings, Dr. Tomas

    2003-01-01

    As part of a federal study of the biology of stress and resilience, a comprehensive, structured stress-history interview (PSEI-NCPV) was administered to 307 participants recruited in Honolulu. A moderate correlation between childhood stress and current depression was found. A relatively high rate of "severe bullying/hazing," and a high mean stress-intensity reating for "blood-drawing induced anxiety" call for further research.

  13. Dipyridamole is superior to dobutamine for thallium stress imaging: a randomised crossover study.

    Kumar, E. B.; Steel, S A; Howey, S; Caplin, J L; Aber, C P

    1994-01-01

    OBJECTIVE--To assess the value of dobutamine over dipyridamole as a pharmacological stressing agent in myocardial perfusion imaging with thallium-201. DESIGN--Stress and redistribution tomographic images were taken in a group of patients in a randomised crossover study of both agents. The scans were scored to give a value for the stress and redistribution images and a reversibility score (redistribution--stress). All patients had coronary angiography that was also scored. Differences between ...

  14. The Effect of Gender on Stress Factors: An Exploratory Study among University Students

    Michelle Calvarese

    2015-01-01

    This study examined the relationship between gender and reactions to stress among university students. University students were surveyed on how they typically responded when under perceived stress. There were significant differences between males and females concerning their reactions to stress. Overall, more females experienced higher levels of depression, frustration, and anxiety than their male counterparts when reacting to stress. Males also tended to have other psychological reactions di...

  15. A case study to determine stress sources affecting the academic performance

    Aytaç Aydın; Kemal Üçüncü; Taner Taşdemir

    2011-01-01

    Job stress affects academicians in terms of performance, scientific production, job satisfaction and health. This effect may differ according to the academicians in the structure of the organization. It is possible to mention about positive stress if organization structure positively affects academician, but it is called negative stress if it negatively affects. Lack of fee and powers, injustice employee evaluation, not getting in return for work are important stress sources. In this study, ...

  16. “A STUDY ON DEPRESSION AND STRESS AMONG COLLEGE STUDENTS IN TIRUCHIRAPALLI TOWN”

    N. Maheswari

    2015-01-01

    Stress affects everyone in a different way. Stress in academic institutions can have both positive and negative consequences if not well managed. Academic institutions have different work settings compared to non-academic and therefore one would expect the differences in symptoms, causes, and consequences of stress. By identifying the sub issues of each component of academic stress among the college students the study provides better insights to the academic administrators for initiating effo...

  17. Teacher Stress and Personal Values. An Exploratory Study

    Bachkirova, Tatiana

    2005-01-01

    This article presents the first stage of a small-scale research project into the relationship between teacher stress and personal values. It starts by outlining the problem of teacher stress and an overview of the literature investigating the sources of it. A particular combination of factors related to personal values that may increase…

  18. Stress in Family Practice Residents: An Exploratory Study Using Art.

    Julliard, Kell; Intilli, Nancy; Ryan, Jennifer; Vollmann, Sarah; Seshadri, Mahalakshmi

    2002-01-01

    Investigates the themes of 16 family practice residents' art work and their characteristics (age, gender, resident year, undergraduate training location) in relationship to stress. Residents' drawing were linked by common themes of psychological pressure, anxiety, a sense of being overwhelmed, and depression. Evidence of stress was more frequently…

  19. Stress, deformation and diffusion interactions in solids - A simulation study

    Fischer, F. D.; Svoboda, Jiří

    2015-01-01

    Roč. 78, MAY (2015), s. 427-442. ISSN 0022-5096 R&D Projects: GA ČR(CZ) GA14-24252S Institutional support: RVO:68081723 Keywords : Diffusion * Bulk * Microstructure * Viscoelastic material * Stress relaxation * Residual stress Subject RIV: BJ - Thermodynamics Impact factor: 3.598, year: 2014

  20. Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination

    Melillo Paolo

    2011-11-01

    Full Text Available Abstract Background This study investigates the variations of Heart Rate Variability (HRV due to a real-life stressor and proposes a classifier based on nonlinear features of HRV for automatic stress detection. Methods 42 students volunteered to participate to the study about HRV and stress. For each student, two recordings were performed: one during an on-going university examination, assumed as a real-life stressor, and one after holidays. Nonlinear analysis of HRV was performed by using Poincaré Plot, Approximate Entropy, Correlation dimension, Detrended Fluctuation Analysis, Recurrence Plot. For statistical comparison, we adopted the Wilcoxon Signed Rank test and for development of a classifier we adopted the Linear Discriminant Analysis (LDA. Results Almost all HRV features measuring heart rate complexity were significantly decreased in the stress session. LDA generated a simple classifier based on the two Poincaré Plot parameters and Approximate Entropy, which enables stress detection with a total classification accuracy, a sensitivity and a specificity rate of 90%, 86%, and 95% respectively. Conclusions The results of the current study suggest that nonlinear HRV analysis using short term ECG recording could be effective in automatically detecting real-life stress condition, such as a university examination.

  1. Is my stress right or wrong? Studying the production of stress by non-native speaking teachers of English

    Ika Apriani Fata

    2014-03-01

    Full Text Available This study aims at exploring the production of stress by non native English teachers in Aceh. It also inquires into how these teachers of English overcame their shortcomings in oral English language teaching. 45 non native English teachers from Aceh were recorded. They came from four regions in the province of Aceh, namely Aceh Timur, Langsa, Aceh Utara and Aceh Besar. The participants have taught English from five to 15 years. The approach used in this paper is qualitative by focusing on the method of lexical stress analysis suggested by Crystal (1969, Halliday (1970 and McCawley (1986.  The study reveals that variations of lexical stresses were produced by the teachers with 13-15 years of teaching experience.  Those from Langsa and Aceh Timur produced the most varied stresses. Therefore, it is suggested for future research to conduct a more in-depth study on this topic with a wider sample of participants and more target words. It is also proposed that possible socio-phonological language inferences in the production of English stress by EFL teachers should be explored.

  2. Effects of a "Brief Stress Management Training Program" from Medical Students’ Viewpoints: A Qualitative Study

    Sepideh Herizchi

    2015-12-01

    Full Text Available Introduction: Medical students undergo many stressors during various stages of medical education and must learn to cope with their new situation. Some studies have reported that stress management training methods have significant effects on decreasing stress in medical students. The aim of this study was to evaluate the efficacy of a "Stress Management Training Session" from medical students’ viewpoints. Methods: This study design employed a qualitative phenomenological research method. Using a goal-directed sampling method, medical students in the psychiatry ward during 3 months, participated in a "Stress Management Training Session". In this section, the nature of stress and some simple techniques for stress management were taught practically. After 1 month, participants cooperated in 3 focus group discussions. In the FGDs students explained their experiences in the stress management session and its effectiveness. After recording and writing discussions, subjects’ content was analyzed. Results: In total, 6 themes and 2:10 subthemes materialized from data analysis. In the students’ opinions, learning and using stress management techniques had good effects on their stress, sleep and headaches. Although some students didn’t notice to the efficacy on concentration, others believed stress management techniques were useful for learning and concentration. Conclusion: Based on the medical students’ opinions, learning and using stress management techniques had good effects on their stress, sleep and headaches and may improve concentration and learning quality.

  3. Parameter study for the laser-driven dielectric accelerator taking account of nonlinear optical effects

    A transmission grating type laser-driven dielectric accelerator (TG-LDA) was performed taking account of the optical damage threshold and the nonlinear optical effects such as the self-phase modulation and self-focus. The maximum laser intensity and the optimum pulse width were concluded to be 1012 W/cm2 and 2 ps, respectively. An irradiation intensity of 5 × 1011W/cm2 was suitable for a silica TG-LDA with a pulse width range from 1 ps to 10 ps. The higher order harmonics of the axial electric field distribution was capable of accelerating electrons provided that the electron speed approximately satisfies the conditions of v/c = 1/2, 1/3, or 1/4. The electrons at the initial energy of 20 kV are accelerated by an acceleration field strength of 20 MV/m, and the electrons were accelerated by higher fields as the speed increased. For relativistic energy electrons, the acceleration gradient was 600 MV/m. The accelerating length and the time to obtain 1 MeV electron were 4 mm and 50 ps, respectively. (author)

  4. Accelerated damage studies of titanate ceramics containing simulated PW-4b and JW-A waste

    Ceramic waste forms are affected by radiation damage, primarily arising from aloha-decay processes that can lead to volume expansion and amorphization of the component crystalline phases. The understanding of the extent and impact of these effects on the overall durability of the waste form is critical to the prediction of their long-term performance under repository conditions. Since 1985 ANSTO and JAERI have carried out joint studies on the use of 244Cm to simulate alpha-radiation damage in ceramic waste forms. These studies have focussed on synroc formulations doped with simulated PW-4b and JW-A wastes. The studies have established the relationship between density change and irradiation levels for Synroc containing JW-A and PW-4b wastes. The storage of samples at 200 C halves the rate of decrease in the density of the samples compared to that measured at room temperature. This effect is consistent with that found for natural samples where the amorphization of natural samples stored under crustal conditions is lower, by factors between 2 and 4, than that measured for samples from accelerated doping experiments stored at room temperature. (J.P.N.)

  5. Analytical bunch compression studies for a linac-based electron accelerator

    Schreck, M.; Wesolowski, P.

    2015-10-01

    The current paper deals with analytical bunch compression studies for FLUTE whose results are compared to simulations. FLUTE is a linac-based electron accelerator with a design energy of approximately 40 MeV currently being constructed at the Karlsruhe Institute of Technology. One of the goals of FLUTE is to generate electron bunches with their length lying in the femtosecond regime. In the first phase this will be accomplished using a magnetic bunch compressor. This compressor forms the subject of the studies presented. The paper is divided into two parts. The first part deals with pure geometric investigations of the bunch compressor where space charge effects and the backreaction of bunches with coherent synchrotron radiation are neglected. The second part is dedicated to the treatment of space charge effects. The upshot is that the analytical results in the two parts agree quite well with what is obtained from simulations. This paper shall form the basis for future analytical studies of the FLUTE bunch compressor and of bunch compression, in general.

  6. Feasibility studies on the direct wire readout on wire scanners in electron accelerators

    This bachelor thesis deals essentially with the signal processing of a so-called wire scanner, a special monitor, which comes to application in the beam diagnostics of particle accelerators. In this direct wire readout the voltage signal, which is induced by the particle beam in the measurement wire of the wire scanner, shall be directly read out. The aim of this thesis is to show fundamental considerations and perform studies, which study, whether and how in the future by means of a suited data transmission as well as readout electronics conclusion on the most important parameters of the beam, like position and profile, are possible. The measurement system presented here is divided in three main components: Signal measurement, signal preparation, and signal stretching. A suited test facility was developed and is presented in detail, in which then all components, like for instance the transmission cables, the wire-scanner fork, and the developed measurement circuit, are studied, which are of importance for a faultless signal transmission and presentation. Extensive measurements on the single components, as well as calculations for the signal transmission on and in the wire scanner were performed, whereby a good agreement could be found. Thereafter a comparison and a selection of the component used in this project were made. Furthermore improvement proposals, new constructions, and outlooks are presented, which could be of importance in further works.

  7. An Economic Study for Establishment GAMMA Irradiation and Electron Beam Accelerator Facilities for Sterilization of Arabic Sudan Gum Export

    This study was carried out to discuss the economic analysis for using gamma irradiation and electron beam accelerators facilities to develop the marketing abilities of exported Arabic Sudan gum by radiation sterilization. This study included the technical marketing aspects and financial analysis for the projects of irradiated Arabic gum.

  8. Psychological and physiological responses to stress: a review based on results from PET and MRI studies

    Cortez, Celia Martins; Cruz, Frederico Alan de Oliveira; Silva, Dilson [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. de Biologia Roberto Alcantara Gomes. Dept. de Ciencias Fisiologicas]. E-mail: ccortez@uerj.br

    2008-12-15

    A new application for the nuclear imaging techniques is the study of organic responses to stress. Neuroimaging techniques allow the assessment of brain activation changes in association with the metabolic responses to stress. In this paper, a review of general effects of the stress on organic activity is made, emphasizing important advances introduced by studies using PET and fMRI. The importance of the hypothalamus-pituitary-adrenal axis to onset the adequate psychical and organic responses to sustain the homeostasis during the stress is discussed, as well as the possibility of traumatic stressing experiences have negative effects on the brain. (author)

  9. Accelerating networks

    Evolving out-of-equilibrium networks have been under intense scrutiny recently. In many real-world settings the number of links added per new node is not constant but depends on the time at which the node is introduced in the system. This simple idea gives rise to the concept of accelerating networks, for which we review an existing definition and-after finding it somewhat constrictive-offer a new definition. The new definition provided here views network acceleration as a time dependent property of a given system as opposed to being a property of the specific algorithm applied to grow the network. The definition also covers both unweighted and weighted networks. As time-stamped network data becomes increasingly available, the proposed measures may be easily applied to such empirical datasets. As a simple case study we apply the concepts to study the evolution of three different instances of Wikipedia, namely, those in English, German, and Japanese, and find that the networks undergo different acceleration regimes in their evolution

  10. Physiological responding to stress in middle-aged males enriched for longevity: a social stress study

    S.W.M. Jansen; D. van Heemst; J. van der Grond; R. Westendorp; N.Y.L. Oei

    2015-01-01

    Individuals enriched for familial longevity display a lower prevalence of age-related diseases, such as cardiovascular- and metabolic diseases. Since these diseases are associated with stress and increased cortisol levels, one of the underlying mechanisms that may contribute to healthy longevity mig

  11. Proton-Proton Colliding-Beam Storage Rings for the National Accelerator Laboratory: Design Study 1968

    None

    1968-01-01

    This report describes the design studies on colliding-beam storage rings carried out at the National Accelerator Laboratory in the summer and fall of 1968. These studies were under the direction of Lee C. Teng. M. Stanley Livingston also played an important part in catalyzing the studies. Dr. Teng's preface, immediately following, gives a chronology of the study and lists the participants in various aspects. The purpose of the study has been to develop realistic cost estimates upon which future plans can be based. It is to be emphasized that this is not a proposal for construction. The major results of the study are that 100-100 BeV colliding beam rings can be built for approximately 75 million dollars (in 1968 dollars), utilizing conventional steel and copper magnets. This estimate includes no equipment for physics experiments. A system utilizing steel magnets that are excited by superconducting coils is estimated to cost somewhat less. A similar system using cryogenic aluminum coils appears to be slightly more costly at this time than the conventional magnet. A number of storage rings built of superconducting magnets have also been analyzed on the premise (undemonstrated as yet) that they would in fact operate satisfactorily. Such magnets designed using present technology for relatively low fields, about 40 kG, appear to be competitive with conventional magnets. Evidently a total colliding-beam facility, including experimental equipment, could be built at NAL for a sum of the order of 100 million 1968 dollars. It should be added that the terms of reference of these design studies gave emphasis to a straightforward, conservative design. Further design work and advances in technology might very well result in a significant reduction in cost or, at the same cost, provide for a greater scope.

  12. Studies of industrial emissions by accelerator-based techniques: A review of applications at CEDAD

    Calcagnile L.

    2012-04-01

    Full Text Available Different research activities are in progress at the Centre for Dating and Diagnostics (CEDAD, University of Salento, in the field of environmental monitoring by exploiting the potentialities given by the different experimental beam lines implemented on the 3 MV Tande-tron accelerator and dedicated to AMS (Accelerator Mass Spectrome-try radiocarbon dating and IB A (Ion Beam Analysis. An overview of these activities is presented by showing how accelerator-based analytical techniques can be a powerful tool for monitoring the anthropogenic carbon dioxide emissions from industrial sources and for the assessment of the biogenic content in SRF (Solid Recovered Fuel burned in WTE (Waste to Energy plants.

  13. Studies of industrial emissions by accelerator-based techniques: A review of applications at CEDAD

    Calcagnile, L.; Quarta, G.

    2012-04-01

    Different research activities are in progress at the Centre for Dating and Diagnostics (CEDAD), University of Salento, in the field of environmental monitoring by exploiting the potentialities given by the different experimental beam lines implemented on the 3 MV Tande-tron accelerator and dedicated to AMS (Accelerator Mass Spectrome-try) radiocarbon dating and IB A (Ion Beam Analysis). An overview of these activities is presented by showing how accelerator-based analytical techniques can be a powerful tool for monitoring the anthropogenic carbon dioxide emissions from industrial sources and for the assessment of the biogenic content in SRF (Solid Recovered Fuel) burned in WTE (Waste to Energy) plants.

  14. STUDY ON RESTRAINING THE RESIDUAL VIBRATION OF FLEXIBLE ARM BY PLANNING ACCELERATION

    Zhu Jian; Shao Hao; Wang Xingsong

    2000-01-01

    The method of planning acceleration is discussed to restrain the residual vibration of flexible arm.Based on the built mathematical model of the flexible arm,the equations of vibration with acceleration,vibration frequency,damping and time are obtained theoretically.According to the vibration frequency and damping,the suitable acceleration is executed experimentally to the flexible arm at the corresponding time.The result shows that this way can give rise to good effect to restrain the residual vibration.

  15. High Energy Particle Accelerators

    Audio Productions, Inc, New York

    1960-01-01

    Film about the different particle accelerators in the US. Nuclear research in the US has developed into a broad and well-balanced program.Tour of accelerator installations, accelerator development work now in progress and a number of typical experiments with high energy particles. Brookhaven, Cosmotron. Univ. Calif. Berkeley, Bevatron. Anti-proton experiment. Negative k meson experiment. Bubble chambers. A section on an electron accelerator. Projection of new accelerators. Princeton/Penn. build proton synchrotron. Argonne National Lab. Brookhaven, PS construction. Cambridge Electron Accelerator; Harvard/MIT. SLAC studying a linear accelerator. Other research at Madison, Wisconsin, Fixed Field Alternate Gradient Focusing. (FFAG) Oakridge, Tenn., cyclotron. Two-beam machine. Comments : Interesting overview of high energy particle accelerators installations in the US in these early years. .

  16. A NUMERICAL STUDY OF THE STRESS DISTRIBUTION IN HOPPER FLOW

    Haiping Zhu; Aibing Yu

    2003-01-01

    The stress distributions of granular flow in a cylindrical hopper with flat bottom are investigated by means of a combined approach of discrete element method (DEM) and averaging method. The filling and discharge of the hopper flow are first simulated at a particle level by means of a modified DEM. The results are then used to determine the velocity and stress profiles of the hopper flow by means of an averaging method. The analysis is focused on a central section plane of the hopper due to the relatively perfect axial symmetry. The velocity profiles are illustrated to be consistent with those obtained by the previous experiments, confirming the validity of the proposed approach. The distributions of four components of the planar stress tensor at different heights are quantified. It is shown that the vertical normal stress increases with increasing the height near the central axis, the horizontal normal stress varies more slowly at a higher level and is almost constant when the height is equal to or greater than about 12 particle diameter, and the magnitudes of two shear stresses are equal at the central zone of the hopper but not so at the points near the walls. The dependence of stress distributions on the wall mechanical properties such as sliding resistance and rolling resistance is also discussed.

  17. Muscle contributions to centre of mass acceleration during turning gait in typically developing children: A simulation study.

    Dixon, Philippe C; Jansen, Karen; Jonkers, Ilse; Stebbins, Julie; Theologis, Tim; Zavatsky, Amy B

    2015-12-16

    Turning while walking requires substantial joint kinematic and kinetic adaptations compared to straight walking in order to redirect the body centre of mass (COM) towards the new walking direction. The role of muscles and external forces in controlling and redirecting the COM during turning remains unclear. The aim of this study was to compare the contributors to COM medio-lateral acceleration during 90° pre-planned turns about the inside limb (spin) and straight walking in typically developing children. Simulations of straight walking and turning gait based on experimental motion data were implemented in OpenSim. The contributors to COM global medio-lateral acceleration during the approach (outside limb) and turn (inside limb) stance phase were quantified via an induced acceleration analysis. Changes in medio-lateral COM acceleration occurred during both turning phases, compared to straight walking (p<0.001). During the approach, outside limb plantarflexors (soleus and medial gastrocnemius) contribution to lateral (away from the turn side) COM acceleration was reduced (p<0.001), whereas during the turn, inside limb plantarflexors (soleus and gastrocnemii) contribution to lateral acceleration (towards the turn side) increased (p≤0.013) and abductor (gluteus medius and minimus) contribution medially decreased (p<0.001), compared to straight walking, together helping accelerate the COM towards the new walking direction. Knowledge of the changes in muscle contributions required to modulate the COM position during turning improves our understanding of the control mechanisms of gait and may be used clinically to guide the management of gait disorders in populations with restricted gait ability. PMID:26555714

  18. Study on finite element analysis technology for weld residual stress

    This paper describes the process of simulation weld flow with live-dead element and calculates the distribution of weld residual stress using the modal of the Ling'ao nuclear power station CRDM upper canopy seal weld, and the residual stress curve has been plotted. The comparison results show that the calculated result accords well with the data of WSI Company. It shows that the analysis technology for weld residual stress can be used to evaluate the repair of CRDM upper canopy. (authors)

  19. Monte Carlo simulation to study the doses in an accelerator BNCT treatment

    In this work the 7Li(p, n)7Be reaction has been studied as a neutron source for accelerator-based BNCT (Boron Neutron Capture Therapy). In order to optimize the design of the neutron production target and the beam shaping assembly, extensive MCNP simulations have been performed. These simulations include a thick Li metal target, a whole-body phantom, a moderator-reflector assembly (Al/AlF3 as moderator and graphite as reflector) and the treatment room. The doses were evaluated for two proton bombarding energies of 1.92 MeV (near to the threshold of the reaction) and 2.3 MeV (near to the resonance of the reaction) and for three Al/ALF3 moderator thicknesses (18, 26 and 34 cm). To assess the doses, a comparison using a Tumor Control Probability (TCP) model was done. In a second instance, the effect of the specific skin radiosensitivity (an RBE of 2.5 for the 10B(n,α)7Li reaction) and a 10B uptake of 17 ppm was considered for the scalp. Finally, the simulations show the advantage of irradiating with near-resonance-energy protons (2.3 MeV) because of the high neutron yield at this energy, leading to the lowest treatment times. Moreover, the 26 cm Al/AlF3 moderator has shown the best performance among the studied cases. (author)

  20. System and safety studies of accelerator driven transmutation. Annual Report 2005

    The results of the research activities on System and Safety of Accelerator-Driven Transmutation (ADS) at the Department of Nuclear and Reactor Physics are described in this report followed by the Appendices of the relevant scientific papers published in 2005. PhD and Licentiate dissertations of Marcus Ericsson, Per Seltborg, Christina Lagerstedt and Daniel Westlen (see Appendices) reflect the research mainstream of 2005. Year 2005 was also very rich in international activities with ADS in focus. Summary of conferences, seminars and lecturing activities is given in Chapter 9 Research activities of 2005 have been focused on several areas: system and safety studies of ADS; subcritical experiments; ADS source efficiency studies; nuclear fuel cycle analysis; potential of reactor based transmutation; ADS fuel development; simulation of radiation damage; and development of codes and methods. Large part of the research activities has been well integrated with the European projects of the 5th and 6th Framework Programmes of the European Commission in which KTH is actively participating. In particular European projects: RED-IMPACT, CONFIRM, FUTURE, EUROTRANS and NURESIM

  1. Studies of niobium and development of niobium resonant RF cavities for accelerator driven system

    The present approach for the fabrication of superconducting radio frequency (SRF) cavities is to roll and deep draw sheets of polycrystalline high-purity niobium. Jefferson Laboratory pioneered the use of large-grain/single-crystal Nb directly sliced from an ingot for the fabrication of single-crystal high-purity Nb SRF cavities. The large grain/single crystal niobium has several potential advantages over the polycrystalline niobium and has become a viable alternative to the standard fine grain (ASTM grain size>6 μm), high purity (RRR ≥ 250 ) niobium for the fabrication of high-performance SRF cavities for particle accelerators. The present study includes the prototype single cell low beta cavity design, fabrication, EB welding and low temperature RF test at 2K. In this study also the medium field Q-Slope has been analyzed with the help of an added non linear term in Heabel's analytical model and a linear increase of surface resistance Rs with the magnetic field

  2. System and safety studies of accelerator driven transmutation Annual Report 2005

    Gudowski, Waclaw; Wallenius, Jan; Arzhanov, Vasily; Jolkkonen, Mikael; Eriksson, Marcus; Seltborg, Per; Westlen, Daniel; Lagerstedt, Christina; Isaksson, Patrick; Persson, Carl-Magnus; Aalander, Alexandra [Royal Inst. of Technology, Stockholm (Sweden). Dept. of Nuclear and Reactor Physics

    2006-11-15

    The results of the research activities on System and Safety of Accelerator-Driven Transmutation (ADS) at the Department of Nuclear and Reactor Physics are described in this report followed by the Appendices of the relevant scientific papers published in 2005. PhD and Licentiate dissertations of Marcus Ericsson, Per Seltborg, Christina Lagerstedt and Daniel Westlen (see Appendices) reflect the research mainstream of 2005. Year 2005 was also very rich in international activities with ADS in focus. Summary of conferences, seminars and lecturing activities is given in Chapter 9 Research activities of 2005 have been focused on several areas: system and safety studies of ADS; subcritical experiments; ADS source efficiency studies; nuclear fuel cycle analysis; potential of reactor based transmutation; ADS fuel development; simulation of radiation damage; and development of codes and methods. Large part of the research activities has been well integrated with the European projects of the 5th and 6th Framework Programmes of the European Commission in which KTH is actively participating. In particular European projects: RED-IMPACT, CONFIRM, FUTURE, EUROTRANS and NURESIM.

  3. Systematic Study of Spin Effects at SPASCHARM Experiment at 70-GeV Accelerator in Protvino

    Mochalov, V. V.; Abramov, V. V.; Bazhanov, N. A.; Borisov, N. S.; Derevschikov, A. A.; Evdokimova, A. S.; Meshchanin, A. P.; Minaev, N. G.; Morozov, D. A.; Nurushev, S. B.; Ryzhikov, S. V.; Semenov, P. A.; Ryazantsev, A. V.; Strikhanov, M. N.; Rykov, V. L.; Usov, Y. A.; Vasiliev, A. N.

    2016-02-01

    A new experiment SPASCHARM for systematic study of polarization phenomena in the inclusive and exclusive hadronic reactions in the energy range of IHEP accelerator U-70 (12-50GeV) is currently under development. The universal experimental setup will detect dozens of various resonances and stable particles produced in collisions of unpolarized beams with the polarized target, and at the next stage, using polarized proton and antiproton beams. At the beginning, the final states consisting of light quarks (u, d, s) will be reconstructed, and later on the charmonium states will be studied. Measurements are planned for a variety of beams: π±,K±,p, antiprotons. Hyperon polarization and spin density matrix elements of the vector mesons will be measured along with the single-spin asymmetry (SSA). The 2π-acceptance in azimuth, which is extremely useful for reduction of systematic errors in measurements of spin observables, will be implemented in the experiment. The solid angle acceptance of the setup, Δθ ≈ 250 mrad vertically and 350 mrad horizontally in the beam fragmentation region, covers a wide range of kinematic variables pT and xF. This provides the opportunity for separating dependences on these two variables which is usually not possible in the setups with a small solid angle acceptance. Unlike some previous polarization experiments, the SPASCHARM will be able to simultaneously accumulate and record data on the both, charged and neutral particle production.

  4. System and safety studies of accelerator driven transmutation. Annual Report 2003

    The research on safety of Accelerator-Driven Transmutation Systems (ADS) at the Dept. of Nuclear and Reactor Physics reported here has been focused on different aspects of safety of the Accelerator-Driven Transmutation Systems and on Transmutation research in more general terms. An overview of the topics of our research is given in the Summary which is followed by detailed reports as separate chapters or subchapters. Some of the research topics reported in this report are referred to appendices, which have been published in the open literature. Topics, which are not yet published, are described with more details in the main part of this report. Main focus has been, as before, largely determined by the programme of the European projects of the 5th Framework Programme in which KTH is actively participating. In particular: a) ADS core design and development of advanced nuclear fuel optimised for high transmutation rates and good safety features. This activity includes even computer modeling of nuclear fuel production. Three different ADS-core concept are being investigated: Conceptual design of Pb-Bi cooled core with nitride fuel so called Sing-Sing Core developed at KTH; Pb-Bi cooled core with oxide fuel so called ANSALDO design for the European Project PDS-XADS; Gas cooled core with oxide fuel a design investigated for the European Project PDS-XADS. b) analysis of potential of advance fuels, in particular nitrides with high content of minor actinides; c) analysis of ADS-dynamics and assessment of major reactivity feedbacks; d) emergency heat removal from ADS; e) participation in ADS: MUSE (CEA-Cadarache), YALINA subcritical experiment in Minsk and designing of the subcritical experiment SAD in Dubna; f) theoretical and simulation studies of radiation damage in high neutron (and/or proton) fluxes; g) computer code and nuclear data development relevant for simulation and optimization of ADS, validation of the MCB code and sensitivity analysis; h) studies of

  5. System and safety studies of accelerator driven transmutation. Annual Report 2003

    Gudowski, Waclaw; Wallenius, Jan; Tucek, Kamil [Royal Inst. of Technology, Stockholm (Sweden). Dept. of Nuclear and Reactor Physics] [and others

    2004-12-01

    The research on safety of Accelerator-Driven Transmutation Systems (ADS) at the Dept. of Nuclear and Reactor Physics reported here has been focused on different aspects of safety of the Accelerator-Driven Transmutation Systems and on Transmutation research in more general terms. An overview of the topics of our research is given in the Summary which is followed by detailed reports as separate chapters or subchapters. Some of the research topics reported in this report are referred to appendices, which have been published in the open literature. Topics, which are not yet published, are described with more details in the main part of this report. Main focus has been, as before, largely determined by the programme of the European projects of the 5th Framework Programme in which KTH is actively participating. In particular: a) ADS core design and development of advanced nuclear fuel optimised for high transmutation rates and good safety features. This activity includes even computer modeling of nuclear fuel production. Three different ADS-core concept are being investigated: Conceptual design of Pb-Bi cooled core with nitride fuel so called Sing-Sing Core developed at KTH; Pb-Bi cooled core with oxide fuel so called ANSALDO design for the European Project PDS-XADS; Gas cooled core with oxide fuel a design investigated for the European Project PDS-XADS. b) analysis of potential of advance fuels, in particular nitrides with high content of minor actinides; c) analysis of ADS-dynamics and assessment of major reactivity feedbacks; d) emergency heat removal from ADS; e) participation in ADS: MUSE (CEA-Cadarache), YALINA subcritical experiment in Minsk and designing of the subcritical experiment SAD in Dubna; f) theoretical and simulation studies of radiation damage in high neutron (and/or proton) fluxes; g) computer code and nuclear data development relevant for simulation and optimization of ADS, validation of the MCB code and sensitivity analysis; h) studies of

  6. Studies and measurements of linear coupling and nonlinearities in hadron circular accelerators

    In this thesis a beam-based method has been developed to measure the strength and the polarity of corrector magnets (skew quadrupoles and sextupoles) in circular accelerators. The algorithm is based on the harmonic analysis (via FFT) of beam position monitor (BPM) data taken turn by turn from an accelerator in operation. It has been shown that, from the differences of the spectral line amplitudes between two consecutive BPMs, both the strength and the polarity of non-linear elements placed in between can be measured. The method has been successfully tested using existing BPM data from the SPS of CERN. A second beam-based method has been studied for a fast measurement and correction of betatron coupling driven by skew quadrupole field errors and tilted focusing quadrupoles. In this thesis it has been shown how the correction for minimizing the coupling stop band C can be performed in a single machine cycle from the harmonic analysis of multi-BPM data. The method has been successfully applied to RHIC. A third theoretical achievement is a new description of the betatron motion close to the difference resonance in presence of linear coupling. New formulae describing the exchange of RMS resonances have been derived here making use of Lie algebra providing a better description of the emittance behavior. A new way to decouple the equations of motion and explicit expressions for the individual single particle invariants have been found. For the first time emittance exchange studies have been carried out in the SIS-18 of GSI. Applications of this manipulation are: emittance equilibration under consideration for future operations of the SIS-18 as booster for the SIS-100; emittance transfer during multi-turn injection to improve the efficiency and to protect the injection septum in high intensity operations, by shifting part of the horizontal emittance into the vertical plane. Multi-particle simulations with 2D PIC space-charge solver have been run to infer heuristic scaling

  7. Studies and measurements of linear coupling and nonlinearities in hadron circular accelerators

    Franchi, A.

    2006-07-01

    In this thesis a beam-based method has been developed to measure the strength and the polarity of corrector magnets (skew quadrupoles and sextupoles) in circular accelerators. The algorithm is based on the harmonic analysis (via FFT) of beam position monitor (BPM) data taken turn by turn from an accelerator in operation. It has been shown that, from the differences of the spectral line amplitudes between two consecutive BPMs, both the strength and the polarity of non-linear elements placed in between can be measured. The method has been successfully tested using existing BPM data from the SPS of CERN. A second beam-based method has been studied for a fast measurement and correction of betatron coupling driven by skew quadrupole field errors and tilted focusing quadrupoles. In this thesis it has been shown how the correction for minimizing the coupling stop band C can be performed in a single machine cycle from the harmonic analysis of multi-BPM data. The method has been successfully applied to RHIC. A third theoretical achievement is a new description of the betatron motion close to the difference resonance in presence of linear coupling. New formulae describing the exchange of RMS resonances have been derived here making use of Lie algebra providing a better description of the emittance behavior. A new way to decouple the equations of motion and explicit expressions for the individual single particle invariants have been found. For the first time emittance exchange studies have been carried out in the SIS-18 of GSI. Applications of this manipulation are: emittance equilibration under consideration for future operations of the SIS-18 as booster for the SIS-100; emittance transfer during multi-turn injection to improve the efficiency and to protect the injection septum in high intensity operations, by shifting part of the horizontal emittance into the vertical plane. Multi-particle simulations with 2D PIC space-charge solver have been run to infer heuristic scaling

  8. Research on accelerator-driven transmutation and studies of experimental facilities

    Takizuka, Takakazu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-11-01

    JAERI is carrying out R and Ds on accelerator-driven transmutation systems under the national OMEGA Program that aims at development of the technology to improve efficiency and safety in the final disposal of radioactive waste. Research facilities for accelerator-driven transmutation experiments are proposed to construct within the framework of the planned JAERI Neutron Science Project. This paper describes the features of the proposed accelerator-driven transmutation systems and their technical issues to be solved. A research facility plan under examination is presented. The plan is divided in two phases. In the second phase, technical feasibility of accelerator-driven systems will be demonstrated with a 30-60 MW experimental integrated system and with a 7 MW high-power target facility. (author)

  9. Contribution to the study of accelerating structure for electrons and respective radiofrequency couplers

    In this work, the experimental results pertaining to the construction and evaluation of a constant gradient accelerating structure and of the radiofrequency couplers are presented. The theoretical methods to determine the initial dimensions of the iris-loaded accelerating structure are presented. The final dimensions have been experimentally determined utilizing four three-cavity sections representing the 4 sup(th), 12 sup(th), 20 sup(th) and 27 sup(th) cavities of the final structure. The diameters of the cavities were corrected for variations of temperature, pressure and humidity. A v sub(p) = c, constant gradient, twelve-cavity prototype of the accelerating structure have been constructed and its principal parameters were experimentally determined according to methods also described in this work. Two prototypes of door-knob type radiofrequency couplers have been constructed and experimental procedures to match and tune the couplers and the accelerating structure were implemented. (author)

  10. Prospective community study of family stress and anxiety in (pre)adolescents: the TRAILS study

    F.V. van Oort; F.C. Verhulst; J. Ormel; A.C. Huizink

    2010-01-01

    For prevention of anxiety in children and adolescents, it is important to know whether family stress is a predictor of anxiety. We studied this in 1,875 adolescents from the Tracking Adolescents’ Individual Lives Survey (TRAILS) who were followed up for 2 years, from age 10-12 to 12-14 years. Adoles

  11. Prospective community study of family stress and anxiety in (pre)adolescents: the TRAILS study

    Van Oort, F.V.A.; Verhulst, F.C.; Ormel, J.; Huizink, A.C.

    2010-01-01

    For prevention of anxiety in children and adolescents, it is important to know whether family stress is a predictor of anxiety. We studied this in 1,875 adolescents from the Tracking Adolescents' Individual Lives Survey (TRAILS) who were followed up for 2 years, from age 10-12 to 12-14 years. Adoles

  12. Prospective community study of family stress and anxiety in (pre)adolescents : the TRAILS study

    van Oort, Floor V. A.; Verhulst, Frank C.; Ormel, Johan; Huizink, Anja C.

    2010-01-01

    For prevention of anxiety in children and adolescents, it is important to know whether family stress is a predictor of anxiety. We studied this in 1,875 adolescents from the Tracking Adolescents' Individual Lives Survey (TRAILS) who were followed up for 2 years, from age 10-12 to 12-14 years. Adoles

  13. Comparison of depth-dose distributions between reactor and accelerator neutron beams proposed by design studies

    Accelerator epithermal neutron beams produced by 7Li(p,n)7Be reactions were compared with reactor neutron beams using a fission converter (20% enriched 235U 5mm-thick plate) from view points of neutron spectrum and depth-dose distributions in a phantom. It is possible to design accelerator epithermal neutron beams having better depth-dose distributions than reactor neutron beams. (author)

  14. Studies on a two-stage design for a high energy heavy ion accelerator

    The most prominent feature of any high energy heavy ions facility is the need for a multi-stage concept. In the first stage ions are accelerated to energies that, after stripping, ensure an abundance of fully ionized particles even for the heaviest elements, in the second stage all kinds of ions can then be accelerated under optimal conditions to extremely high energies and can eventually be stored for experiments with colliding ion beams. (orig./WL)

  15. Electron cloud studies for CERN particle accelerators and simulation code development

    Iadarola, Giovanni

    2014-01-01

    In a particle accelerator free electrons in the beam chambers can be generated by different mechanisms like the ionization of the residual gas or the photoemission from the chamber’s wall due to the synchrotron radiation emitted by the beam. The electromagnetic field of the beam can accelerate these electrons and project them onto the chamber’s wall. According to their impact energy and to the Secondary Electron Yield (SEY) of the surface, secondary electrons can be generated. Especially...

  16. An Experimental Study on Lateral Acceleration of Cars in Different Environments in Sichuan, Southwest China

    Xu, Jin; Yang, Kui; Shao, Yiming; Lu, Gongyuan

    2015-01-01

    In view of the tremendous improvements in the dynamic performance of automobiles and changes in the composition of drivers over the past several decades, it is valuable to examine the distribution of automobile’s lateral acceleration in new environments. The lateral accelerations, speeds, and trajectory curvatures of a passenger car on twelve highways with different design speeds and topographies were obtained. By synchronizing, matching, and counting, the distribution of the lateral accelera...

  17. A Study of the Design of Acceleration Control System for Missiles

    Kajita, Takanori; Eguchi, Hirofumi

    A 2-degrees of freedom PID controller is designed for a maneuvering acceleration control system. This design method is based on the combination of PID and IPD controller. Results show that (1) IP controller is superior to PI controller for the damper loop controller, (2) the selection of PI or IP controller as for the acceleration controller depends on the tradeoffs between the responsibility and the reduction of inverse response.

  18. Two-year follow-up of an open-label multicenter study of polyacrylamide hydrogel (Bulkamid®) for female stress and stress-predominant mixed incontinence

    Toozs-Hobson, Philip; Al-Singary, Waleed; Fynes, Michelle;

    2012-01-01

    Polyacrylamide hydrogel (PAHG, Bulkamid®) is a promising urethral bulking agent. This article presents the 2-year follow-up results of a multicenter study of PAHG injections for treating stress and stress-predominant mixed urinary incontinence....

  19. Hypothalamic circuit regulating colonic transit following chronic stress in rats.

    Yoshimoto, Sazu; Cerjak, Diana; Babygirija, Reji; Bulbul, Mehmet; Ludwig, Kirk; Takahashi, Toku

    2012-03-01

    Although acute stress accelerates colonic transit, the effect of chronic stress on colonic transit remains unclear. In this study, rats received repeated restraint stress (chronic homotypic stress) or various types of stress (chronic heterotypic stress) for 5 and 7 days, respectively. Vehicle saline, oxytocin (OXT), OXT receptor antagonist or corticotropin-releasing factor (CRF) receptor antagonists were administered by intracerebroventricular (ICV) injection prior to restraint stress for 90 min. Immediately after the stress exposure, the entire colon was removed and the geometric center (GC) of Na51CrO4 (a nonabsorbable radioactive marker; 0.5 μCi) distribution was calculated to measure the transit. Gene expression of OXT and CRF in the paraventricular nucleus (PVN) was evaluated by in situ hybridization. Accelerated colonic transit with the acute stressor was no longer observed following chronic homotypic stress. This restored colonic transit was reversed by ICV injection of an OXT antagonist. In contrast, chronic heterotypic stress significantly accelerated colonic transit, which was attenuated by ICV injection of OXT and by a CRF receptor 1 antagonist. OXT mRNA expression in the PVN was significantly increased following chronic homotypic stress, but not chronic heterotypic stress. However, CRF mRNA expression in the PVN was significantly increased following acute and chronic heterotypic stress, but not chronic homotypic stress. These results indicate that central OXT and CRF play a pivotal role in mediating the colonic dysmotility following chronic stress in rats. PMID:21936687

  20. Remote detection of air pollution stress to vegetation - Laboratory-level studies

    Westman, Walter E.; Price, Curtis V.

    1987-01-01

    An experimental investigation of the role of leaf chemistry, anatomy, moisture content, and canopy density on spectral reflectance in healthy and pollution stressed western conifer needles and broad-leafed species of California coastal sage scrub is presented. Acid mist at a level of pH 2.0 is found to more severely effect chlorophyll loss and leaf death than ozone at a level of 0.2 ppm for a four-week period. Both pollutants cause water loss, affecting Bands 4 and 5 in nonlinear ways. The infrared bands initially rise as free water is lost, and subsequently, scattering and reflectance decline. The net effect is shown to be a reduction in TM 4/3 and a rise in TM 5/4 with pollution stress. Under more severe pollution stresses, the decline of leaf area indices due to accelerated leaf drop accentuates the expected TM 4/3 and TM 5/4 changes.