WorldWideScience

Sample records for accelerated similarity searching

  1. SW#db: GPU-Accelerated Exact Sequence Similarity Database Search.

    Matija Korpar

    Full Text Available In recent years we have witnessed a growth in sequencing yield, the number of samples sequenced, and as a result-the growth of publicly maintained sequence databases. The increase of data present all around has put high requirements on protein similarity search algorithms with two ever-opposite goals: how to keep the running times acceptable while maintaining a high-enough level of sensitivity. The most time consuming step of similarity search are the local alignments between query and database sequences. This step is usually performed using exact local alignment algorithms such as Smith-Waterman. Due to its quadratic time complexity, alignments of a query to the whole database are usually too slow. Therefore, the majority of the protein similarity search methods prior to doing the exact local alignment apply heuristics to reduce the number of possible candidate sequences in the database. However, there is still a need for the alignment of a query sequence to a reduced database. In this paper we present the SW#db tool and a library for fast exact similarity search. Although its running times, as a standalone tool, are comparable to the running times of BLAST, it is primarily intended to be used for exact local alignment phase in which the database of sequences has already been reduced. It uses both GPU and CPU parallelization and was 4-5 times faster than SSEARCH, 6-25 times faster than CUDASW++ and more than 20 times faster than SSW at the time of writing, using multiple queries on Swiss-prot and Uniref90 databases.

  2. Approximate similarity search

    Amato, Giuseppe

    2000-01-01

    Similarity searching is fundamental in various application areas. Recently it has attracted much attention in the database community because of the growing need to deal with large volume of data. Consequently, efficiency has become a matter of concern in design. Although much has been done to develop structures able to perform fast similarity search, results are still not satisfactory, and more research is needed. The performance of similarity search for complex features deteriorates and does...

  3. Multivariate Time Series Similarity Searching

    Jimin Wang; Yuelong Zhu; Shijin Li; Dingsheng Wan; Pengcheng Zhang

    2014-01-01

    Multivariate time series (MTS) datasets are very common in various financial, multimedia, and hydrological fields. In this paper, a dimension-combination method is proposed to search similar sequences for MTS. Firstly, the similarity of single-dimension series is calculated; then the overall similarity of the MTS is obtained by synthesizing each of the single-dimension similarity based on weighted BORDA voting method. The dimension-combination method could use the existing similarity searchin...

  4. Scaling Group Testing Similarity Search

    Iscen, Ahmet; Amsaleg, Laurent; Furon, Teddy

    2016-01-01

    The large dimensionality of modern image feature vectors, up to thousands of dimensions, is challenging the high dimensional indexing techniques. Traditional approaches fail at returning good quality results within a response time that is usable in practice. However, similarity search techniques inspired by the group testing framework have recently been proposed in an attempt to specifically defeat the curse of dimensionality. Yet, group testing does not scale and fails at indexing very large...

  5. Accelerated Profile HMM Searches.

    Sean R Eddy

    2011-10-01

    Full Text Available Profile hidden Markov models (profile HMMs and probabilistic inference methods have made important contributions to the theory of sequence database homology search. However, practical use of profile HMM methods has been hindered by the computational expense of existing software implementations. Here I describe an acceleration heuristic for profile HMMs, the "multiple segment Viterbi" (MSV algorithm. The MSV algorithm computes an optimal sum of multiple ungapped local alignment segments using a striped vector-parallel approach previously described for fast Smith/Waterman alignment. MSV scores follow the same statistical distribution as gapped optimal local alignment scores, allowing rapid evaluation of significance of an MSV score and thus facilitating its use as a heuristic filter. I also describe a 20-fold acceleration of the standard profile HMM Forward/Backward algorithms using a method I call "sparse rescaling". These methods are assembled in a pipeline in which high-scoring MSV hits are passed on for reanalysis with the full HMM Forward/Backward algorithm. This accelerated pipeline is implemented in the freely available HMMER3 software package. Performance benchmarks show that the use of the heuristic MSV filter sacrifices negligible sensitivity compared to unaccelerated profile HMM searches. HMMER3 is substantially more sensitive and 100- to 1000-fold faster than HMMER2. HMMER3 is now about as fast as BLAST for protein searches.

  6. Semantically enabled image similarity search

    Casterline, May V.; Emerick, Timothy; Sadeghi, Kolia; Gosse, C. A.; Bartlett, Brent; Casey, Jason

    2015-05-01

    Georeferenced data of various modalities are increasingly available for intelligence and commercial use, however effectively exploiting these sources demands a unified data space capable of capturing the unique contribution of each input. This work presents a suite of software tools for representing geospatial vector data and overhead imagery in a shared high-dimension vector or embedding" space that supports fused learning and similarity search across dissimilar modalities. While the approach is suitable for fusing arbitrary input types, including free text, the present work exploits the obvious but computationally difficult relationship between GIS and overhead imagery. GIS is comprised of temporally-smoothed but information-limited content of a GIS, while overhead imagery provides an information-rich but temporally-limited perspective. This processing framework includes some important extensions of concepts in literature but, more critically, presents a means to accomplish them as a unified framework at scale on commodity cloud architectures.

  7. Biosequence Similarity Search on the Mercury System

    Krishnamurthy, Praveen; Buhler, Jeremy; Chamberlain, Roger; Franklin, Mark; Gyang, Kwame; Jacob, Arpith; Lancaster, Joseph

    2007-01-01

    Biosequence similarity search is an important application in modern molecular biology. Search algorithms aim to identify sets of sequences whose extensional similarity suggests a common evolutionary origin or function. The most widely used similarity search tool for biosequences is BLAST, a program designed to compare query sequences to a database. Here, we present the design of BLASTN, the version of BLAST that searches DNA sequences, on the Mercury system, an architecture that supports high...

  8. Similarity Measures for Boolean Search Request Formulations.

    Radecki, Tadeusz

    1982-01-01

    Proposes a means for determining the similarity between search request formulations in online information retrieval systems, and discusses the use of similarity measures for clustering search formulations and document files in such systems. Experimental results using the proposed methods are presented in three tables. A reference list is provided.…

  9. Protein structural similarity search by Ramachandran codes

    Chang Chih-Hung; Huang Po-Jung; Lo Wei-Cheng; Lyu Ping-Chiang

    2007-01-01

    Abstract Background Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed, several methods have been designed to reduce three-dimensional protein structures to one-dimensional text strings that are then analyzed by traditional sequence alignment methods; however, the accuracy is usually sacrificed and the speed is still unable to match sequence similarity search tools. Here, we ai...

  10. Protein structural similarity search by Ramachandran codes

    Chang Chih-Hung

    2007-08-01

    Full Text Available Abstract Background Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed, several methods have been designed to reduce three-dimensional protein structures to one-dimensional text strings that are then analyzed by traditional sequence alignment methods; however, the accuracy is usually sacrificed and the speed is still unable to match sequence similarity search tools. Here, we aimed to improve the linear encoding methodology and develop efficient search tools that can rapidly retrieve structural homologs from large protein databases. Results We propose a new linear encoding method, SARST (Structural similarity search Aided by Ramachandran Sequential Transformation. SARST transforms protein structures into text strings through a Ramachandran map organized by nearest-neighbor clustering and uses a regenerative approach to produce substitution matrices. Then, classical sequence similarity search methods can be applied to the structural similarity search. Its accuracy is similar to Combinatorial Extension (CE and works over 243,000 times faster, searching 34,000 proteins in 0.34 sec with a 3.2-GHz CPU. SARST provides statistically meaningful expectation values to assess the retrieved information. It has been implemented into a web service and a stand-alone Java program that is able to run on many different platforms. Conclusion As a database search method, SARST can rapidly distinguish high from low similarities and efficiently retrieve homologous structures. It demonstrates that the easily accessible linear encoding methodology has the potential to serve as a foundation for efficient protein structural similarity search tools. These search tools are supposed applicable to automated and high-throughput functional annotations or predictions for the ever increasing number of published protein structures in this post-genomic era.

  11. Secure sketch search for document similarity

    Örencik, Cengiz; Orencik, Cengiz; Alewiwi, Mahmoud Khaled; SAVAŞ, Erkay; Savas, Erkay

    2015-01-01

    Document similarity search is an important problem that has many applications especially in outsourced data. With the wide spread of cloud computing, users tend to outsource their data to remote servers which are not necessarily trusted. This leads to the problem of protecting the privacy of sensitive data. We design and implement two secure similarity search schemes for textual documents utilizing locality sensitive hashing techniques for cosine similarity. While the first one provides very ...

  12. Efficient Authentication of Outsourced String Similarity Search

    Dong, Boxiang; Wang, Hui

    2016-01-01

    Cloud computing enables the outsourcing of big data analytics, where a third party server is responsible for data storage and processing. In this paper, we consider the outsourcing model that provides string similarity search as the service. In particular, given a similarity search query, the service provider returns all strings from the outsourced dataset that are similar to the query string. A major security concern of the outsourcing paradigm is to authenticate whether the service provider...

  13. Mobile P2P Fast Similarity Search

    Bocek, T; Hecht, F. V.; Hausheer, D; Hunt, E; Stiller, B.

    2009-01-01

    In informal data sharing environments, misspellings cause problems for data indexing and retrieval. This is even more pronounced in mobile environments, in which devices with limited input devices are used. In a mobile environment, similarity search algorithms for finding misspelled data need to account for limited CPU and bandwidth. This demo shows P2P fast similarity search (P2PFastSS) running on mobile phones and laptops that is tailored to uncertain data entry and use...

  14. Multiresolution Similarity Search in Image Databases

    Heczko, Martin; Hinneburg, Alexander; Keim, Daniel A.; Wawryniuk, Markus

    2004-01-01

    Typically searching image collections is based on features of the images. In most cases the features are based on the color histogram of the images. Similarity search based on color histograms is very efficient, but the quality of the search results is often rather poor. One of the reasons is that histogram-based systems only support a specific form of global similarity using the whole histogram as one vector. But there is more information in a histogram than the distribution of colors. This ...

  15. Representation Independent Proximity and Similarity Search

    Chodpathumwan, Yodsawalai; Aleyasin, Amirhossein; Termehchy, Arash; Sun, Yizhou

    2015-01-01

    Finding similar or strongly related entities in a graph database is a fundamental problem in data management and analytics with applications in similarity query processing, entity resolution, and pattern matching. Similarity search algorithms usually leverage the structural properties of the data graph to quantify the degree of similarity or relevance between entities. Nevertheless, the same information can be represented in many different structures and the structural properties observed ove...

  16. Web Search Results Summarization Using Similarity Assessment

    Sawant V.V.

    2014-06-01

    Full Text Available Now day’s internet has become part of our life, the WWW is most important service of internet because it allows presenting information such as document, imaging etc. The WWW grows rapidly and caters to a diversified levels and categories of users. For user specified results web search results are extracted. Millions of information pouring online, users has no time to surf the contents completely .Moreover the information available is repeated or duplicated in nature. This issue has created the necessity to restructure the search results that could yield results summarized. The proposed approach comprises of different feature extraction of web pages. Web page visual similarity assessment has been employed to address the problems in different fields including phishing, web archiving, web search engine etc. In this approach, initially by enters user query the number of search results get stored. The Earth Mover's Distance is used to assessment of web page visual similarity, in this technique take the web page as a low resolution image, create signature of that web page image with color and co-ordinate features .Calculate the distance between web pages by applying EMD method. Compute the Layout Similarity value by using tag comparison algorithm and template comparison algorithm. Textual similarity is computed by using cosine similarity, and hyperlink analysis is performed to compute outward links. The final similarity value is calculated by fusion of layout, text, hyperlink and EMD value. Once the similarity matrix is found clustering is employed with the help of connected component. Finally group of similar web pages i.e. summarized results get displayed to user. Experiment conducted to demonstrate the effectiveness of four methods to generate summarized result on different web pages and user queries also.

  17. SEAL: Spatio-Textual Similarity Search

    Fan, Ju; Zhou, Lizhu; Chen, Shanshan; Hu, Jun

    2012-01-01

    Location-based services (LBS) have become more and more ubiquitous recently. Existing methods focus on finding relevant points-of-interest (POIs) based on users' locations and query keywords. Nowadays, modern LBS applications generate a new kind of spatio-textual data, regions-of-interest (ROIs), containing region-based spatial information and textual description, e.g., mobile user profiles with active regions and interest tags. To satisfy search requirements on ROIs, we study a new research problem, called spatio-textual similarity search: Given a set of ROIs and a query ROI, we find the similar ROIs by considering spatial overlap and textual similarity. Spatio-textual similarity search has many important applications, e.g., social marketing in location-aware social networks. It calls for an efficient search method to support large scales of spatio-textual data in LBS systems. To this end, we introduce a filter-and-verification framework to compute the answers. In the filter step, we generate signatures for ...

  18. New similarity search based glioma grading

    MR-based differentiation between low- and high-grade gliomas is predominately based on contrast-enhanced T1-weighted images (CE-T1w). However, functional MR sequences as perfusion- and diffusion-weighted sequences can provide additional information on tumor grade. Here, we tested the potential of a recently developed similarity search based method that integrates information of CE-T1w and perfusion maps for non-invasive MR-based glioma grading. We prospectively included 37 untreated glioma patients (23 grade I/II, 14 grade III gliomas), in whom 3T MRI with FLAIR, pre- and post-contrast T1-weighted, and perfusion sequences was performed. Cerebral blood volume, cerebral blood flow, and mean transit time maps as well as CE-T1w images were used as input for the similarity search. Data sets were preprocessed and converted to four-dimensional Gaussian Mixture Models that considered correlations between the different MR sequences. For each patient, a so-called tumor feature vector (= probability-based classifier) was defined and used for grading. Biopsy was used as gold standard, and similarity based grading was compared to grading solely based on CE-T1w. Accuracy, sensitivity, and specificity of pure CE-T1w based glioma grading were 64.9%, 78.6%, and 56.5%, respectively. Similarity search based tumor grading allowed differentiation between low-grade (I or II) and high-grade (III) gliomas with an accuracy, sensitivity, and specificity of 83.8%, 78.6%, and 87.0%. Our findings indicate that integration of perfusion parameters and CE-T1w information in a semi-automatic similarity search based analysis improves the potential of MR-based glioma grading compared to CE-T1w data alone. (orig.)

  19. New similarity search based glioma grading

    Haegler, Katrin; Brueckmann, Hartmut; Linn, Jennifer [Ludwig-Maximilians-University of Munich, Department of Neuroradiology, Munich (Germany); Wiesmann, Martin; Freiherr, Jessica [RWTH Aachen University, Department of Neuroradiology, Aachen (Germany); Boehm, Christian [Ludwig-Maximilians-University of Munich, Department of Computer Science, Munich (Germany); Schnell, Oliver; Tonn, Joerg-Christian [Ludwig-Maximilians-University of Munich, Department of Neurosurgery, Munich (Germany)

    2012-08-15

    MR-based differentiation between low- and high-grade gliomas is predominately based on contrast-enhanced T1-weighted images (CE-T1w). However, functional MR sequences as perfusion- and diffusion-weighted sequences can provide additional information on tumor grade. Here, we tested the potential of a recently developed similarity search based method that integrates information of CE-T1w and perfusion maps for non-invasive MR-based glioma grading. We prospectively included 37 untreated glioma patients (23 grade I/II, 14 grade III gliomas), in whom 3T MRI with FLAIR, pre- and post-contrast T1-weighted, and perfusion sequences was performed. Cerebral blood volume, cerebral blood flow, and mean transit time maps as well as CE-T1w images were used as input for the similarity search. Data sets were preprocessed and converted to four-dimensional Gaussian Mixture Models that considered correlations between the different MR sequences. For each patient, a so-called tumor feature vector (= probability-based classifier) was defined and used for grading. Biopsy was used as gold standard, and similarity based grading was compared to grading solely based on CE-T1w. Accuracy, sensitivity, and specificity of pure CE-T1w based glioma grading were 64.9%, 78.6%, and 56.5%, respectively. Similarity search based tumor grading allowed differentiation between low-grade (I or II) and high-grade (III) gliomas with an accuracy, sensitivity, and specificity of 83.8%, 78.6%, and 87.0%. Our findings indicate that integration of perfusion parameters and CE-T1w information in a semi-automatic similarity search based analysis improves the potential of MR-based glioma grading compared to CE-T1w data alone. (orig.)

  20. Comparison of Two ``Document Similarity Search Engines''

    Poinçot, Phillipe; Lesteven, Soizick; Murtagh, Fionn

    We have developed and used the ``CDS document map'' based on neural networks (Kohonen maps) http://simbad.u-strasbg.fr/A+A/map.pl In this self-organizing map, documents are gradually clustered by subject themes. The tool is based on keywords associated with the documents. For one selected document, we locate it on the CDS document map and retrieve articles clustered in the same area. The second search engine, used by the ADS (NASA Astrophysics Data System http://cdsads.u-strasbg.fr http://adswww.harvard.edu http://ads.nao.ac.jp, has the capability to find all similar abstracts in the ADS database, with ``keyword request''. We have compared the results of the document similarity search engines, using the same set of documents. One example will be described and results will be discussed.

  1. Efficient Video Similarity Measurement and Search

    Cheung, S-C S

    2002-12-19

    The amount of information on the world wide web has grown enormously since its creation in 1990. Duplication of content is inevitable because there is no central management on the web. Studies have shown that many similar versions of the same text documents can be found throughout the web. This redundancy problem is more severe for multimedia content such as web video sequences, as they are often stored in multiple locations and different formats to facilitate downloading and streaming. Similar versions of the same video can also be found, unknown to content creators, when web users modify and republish original content using video editing tools. Identifying similar content can benefit many web applications and content owners. For example, it will reduce the number of similar answers to a web search and identify inappropriate use of copyright content. In this dissertation, they present a system architecture and corresponding algorithms to efficiently measure, search, and organize similar video sequences found on any large database such as the web.

  2. Earthquake detection through computationally efficient similarity search.

    Yoon, Clara E; O'Reilly, Ossian; Bergen, Karianne J; Beroza, Gregory C

    2015-12-01

    Seismology is experiencing rapid growth in the quantity of data, which has outpaced the development of processing algorithms. Earthquake detection-identification of seismic events in continuous data-is a fundamental operation for observational seismology. We developed an efficient method to detect earthquakes using waveform similarity that overcomes the disadvantages of existing detection methods. Our method, called Fingerprint And Similarity Thresholding (FAST), can analyze a week of continuous seismic waveform data in less than 2 hours, or 140 times faster than autocorrelation. FAST adapts a data mining algorithm, originally designed to identify similar audio clips within large databases; it first creates compact "fingerprints" of waveforms by extracting key discriminative features, then groups similar fingerprints together within a database to facilitate fast, scalable search for similar fingerprint pairs, and finally generates a list of earthquake detections. FAST detected most (21 of 24) cataloged earthquakes and 68 uncataloged earthquakes in 1 week of continuous data from a station located near the Calaveras Fault in central California, achieving detection performance comparable to that of autocorrelation, with some additional false detections. FAST is expected to realize its full potential when applied to extremely long duration data sets over a distributed network of seismic stations. The widespread application of FAST has the potential to aid in the discovery of unexpected seismic signals, improve seismic monitoring, and promote a greater understanding of a variety of earthquake processes. PMID:26665176

  3. Performance Evaluation and Optimization of Math-Similarity Search

    Zhang, Qun; Youssef, Abdou

    2015-01-01

    Similarity search in math is to find mathematical expressions that are similar to a user's query. We conceptualized the similarity factors between mathematical expressions, and proposed an approach to math similarity search (MSS) by defining metrics based on those similarity factors [11]. Our preliminary implementation indicated the advantage of MSS compared to non-similarity based search. In order to more effectively and efficiently search similar math expressions, MSS is further optimized. ...

  4. Self-Taught Hashing for Fast Similarity Search

    Zhang, Dell; Cai, Deng; Lu, Jinsong

    2010-01-01

    The ability of fast similarity search at large scale is of great importance to many Information Retrieval (IR) applications. A promising way to accelerate similarity search is semantic hashing which designs compact binary codes for a large number of documents so that semantically similar documents are mapped to similar codes (within a short Hamming distance). Although some recently proposed techniques are able to generate high-quality codes for documents known in advance, obtaining the codes for previously unseen documents remains to be a very challenging problem. In this paper, we emphasise this issue and propose a novel Self-Taught Hashing (STH) approach to semantic hashing: we first find the optimal $l$-bit binary codes for all documents in the given corpus via unsupervised learning, and then train $l$ classifiers via supervised learning to predict the $l$-bit code for any query document unseen before. Our experiments on three real-world text datasets show that the proposed approach using binarised Laplaci...

  5. Non-accelerator neutrino mass searches

    Zuber, K.

    2000-01-01

    The current status of non-accelerator based searches for effects of a non-vanishing neutrino mass is reviewed. Beside the direct kinematical methods this includes searches for magnetic moments and a discussion of the solar neutrino problem. Double beta decay is not included.

  6. Web Search Results Summarization Using Similarity Assessment

    Sawant V.V.; Takale S.A.

    2014-01-01

    Now day’s internet has become part of our life, the WWW is most important service of internet because it allows presenting information such as document, imaging etc. The WWW grows rapidly and caters to a diversified levels and categories of users. For user specified results web search results are extracted. Millions of information pouring online, users has no time to surf the contents completely .Moreover the information available is repeated or duplicated in nature. This issue has created th...

  7. Outsourced similarity search on metric data assets

    Yiu, Man Lung; Assent, Ira; Jensen, Christian Søndergaard;

    2012-01-01

    This paper considers a cloud computing setting in which similarity querying of metric data is outsourced to a service provider. The data is to be revealed only to trusted users, not to the service provider or anyone else. Users query the server for the most similar data objects to a query example...

  8. A Similarity Search Using Molecular Topological Graphs

    Yoshifumi Fukunishi

    2009-01-01

    Full Text Available A molecular similarity measure has been developed using molecular topological graphs and atomic partial charges. Two kinds of topological graphs were used. One is the ordinary adjacency matrix and the other is a matrix which represents the minimum path length between two atoms of the molecule. The ordinary adjacency matrix is suitable to compare the local structures of molecules such as functional groups, and the other matrix is suitable to compare the global structures of molecules. The combination of these two matrices gave a similarity measure. This method was applied to in silico drug screening, and the results showed that it was effective as a similarity measure.

  9. Query-dependent banding (QDB for faster RNA similarity searches.

    Eric P Nawrocki

    2007-03-01

    Full Text Available When searching sequence databases for RNAs, it is desirable to score both primary sequence and RNA secondary structure similarity. Covariance models (CMs are probabilistic models well-suited for RNA similarity search applications. However, the computational complexity of CM dynamic programming alignment algorithms has limited their practical application. Here we describe an acceleration method called query-dependent banding (QDB, which uses the probabilistic query CM to precalculate regions of the dynamic programming lattice that have negligible probability, independently of the target database. We have implemented QDB in the freely available Infernal software package. QDB reduces the average case time complexity of CM alignment from LN(2.4 to LN(1.3 for a query RNA of N residues and a target database of L residues, resulting in a 4-fold speedup for typical RNA queries. Combined with other improvements to Infernal, including informative mixture Dirichlet priors on model parameters, benchmarks also show increased sensitivity and specificity resulting from improved parameterization.

  10. Fast similarity search in peer-to-peer networks

    Bocek, T; Hunt, E; Hausheer, D; Stiller, B.

    2008-01-01

    Peer-to-peer (P2P) systems show numerous advantages over centralized systems, such as load balancing, scalability, and fault tolerance, and they require certain functionality, such as search, repair, and message and data transfer. In particular, structured P2P networks perform an exact search in logarithmic time proportional to the number of peers. However, keyword similarity search in a structured P2P network remains a challenge. Similarity search for service discovery can significantly impr...

  11. Outsourced similarity search on metric data assets

    Yiu, Man Lung

    2012-02-01

    This paper considers a cloud computing setting in which similarity querying of metric data is outsourced to a service provider. The data is to be revealed only to trusted users, not to the service provider or anyone else. Users query the server for the most similar data objects to a query example. Outsourcing offers the data owner scalability and a low-initial investment. The need for privacy may be due to the data being sensitive (e.g., in medicine), valuable (e.g., in astronomy), or otherwise confidential. Given this setting, the paper presents techniques that transform the data prior to supplying it to the service provider for similarity queries on the transformed data. Our techniques provide interesting trade-offs between query cost and accuracy. They are then further extended to offer an intuitive privacy guarantee. Empirical studies with real data demonstrate that the techniques are capable of offering privacy while enabling efficient and accurate processing of similarity queries.

  12. The Time Course of Similarity Effects in Visual Search

    Guest, Duncan; Lamberts, Koen

    2011-01-01

    It is well established that visual search becomes harder when the similarity between target and distractors is increased and the similarity between distractors is decreased. However, in models of visual search, similarity is typically treated as a static, time-invariant property of the relation between objects. Data from other perceptual tasks…

  13. Search for Dark Photons with Accelerators

    Merkel Harald

    2014-01-01

    Full Text Available A dark photon as the mediator of an interaction of the dark sector is a well motivated extension of the standard model. While possible dark matter particles are heavy and seem to be beyond the reach of current accelerators, the dark photon is not necessarily heavy and might have a mass in the range of existing accelerators. In recent years, an extensive experimental program at several accelerators for the search for dark photons were established. In this talk, recent results and progress in the determination of exclusion limits with accelerators is presented.

  14. Learning Style Similarity for Searching Infographics

    Saleh, Babak; Dontcheva, Mira; Hertzmann, Aaron; Liu, Zhicheng

    2015-01-01

    Infographics are complex graphic designs integrating text, images, charts and sketches. Despite the increasing popularity of infographics and the rapid growth of online design portfolios, little research investigates how we can take advantage of these design resources. In this paper we present a method for measuring the style similarity between infographics. Based on human perception data collected from crowdsourced experiments, we use computer vision and machine learning algorithms to learn ...

  15. A Similarity Search Using Molecular Topological Graphs

    2009-01-01

    A molecular similarity measure has been developed using molecular topological graphs and atomic partial charges. Two kinds of topological graphs were used. One is the ordinary adjacency matrix and the other is a matrix which represents the minimum path length between two atoms of the molecule. The ordinary adjacency matrix is suitable to compare the local structures of molecules such as functional groups, and the other matrix is suitable to compare the global structures of molecules. The comb...

  16. Visual similarity is stronger than semantic similarity in guiding visual search for numbers

    Godwin, H.J.; Hout, M.C.; Menneer, T.

    2014-01-01

    Using a visual search task, we explored how behavior is influenced by both visual and semantic information. We recorded participants’ eye movements as they searched for a single target number in a search array of single-digit numbers (0–9). We examined the probability of fixating the various distractors as a function of two key dimensions: the visual similarity between the target and each distractor, and the semantic similarity (i.e., the numerical distance) between the target and each distra...

  17. Fast and secure similarity search in high dimensional space

    Furon, Teddy; Jégou, Hervé; Amsaleg, Laurent; Mathon, Benjamin

    2013-01-01

    Similarity search in high dimensional space database is split into two worlds: i) fast, scalable, and approximate search algorithms which are not secure, and ii) search protocols based on secure computation which are not scalable. This paper presents a one-way privacy protocol that lies in between these two worlds. Approximate metrics for the cosine similarity allows speed. Elements of large random matrix theory provides security evidences if the size of the database is not too big with respe...

  18. Distributed efficient similarity search mechanism in wireless sensor networks.

    Ahmed, Khandakar; Gregory, Mark A

    2015-01-01

    The Wireless Sensor Network similarity search problem has received considerable research attention due to sensor hardware imprecision and environmental parameter variations. Most of the state-of-the-art distributed data centric storage (DCS) schemes lack optimization for similarity queries of events. In this paper, a DCS scheme with metric based similarity searching (DCSMSS) is proposed. DCSMSS takes motivation from vector distance index, called iDistance, in order to transform the issue of similarity searching into the problem of an interval search in one dimension. In addition, a sector based distance routing algorithm is used to efficiently route messages. Extensive simulation results reveal that DCSMSS is highly efficient and significantly outperforms previous approaches in processing similarity search queries. PMID:25751081

  19. Distributed Efficient Similarity Search Mechanism in Wireless Sensor Networks

    Khandakar Ahmed

    2015-03-01

    Full Text Available The Wireless Sensor Network similarity search problem has received considerable research attention due to sensor hardware imprecision and environmental parameter variations. Most of the state-of-the-art distributed data centric storage (DCS schemes lack optimization for similarity queries of events. In this paper, a DCS scheme with metric based similarity searching (DCSMSS is proposed. DCSMSS takes motivation from vector distance index, called iDistance, in order to transform the issue of similarity searching into the problem of an interval search in one dimension. In addition, a sector based distance routing algorithm is used to efficiently route messages. Extensive simulation results reveal that DCSMSS is highly efficient and significantly outperforms previous approaches in processing similarity search queries.

  20. Accelerating Neuroimage Registration through Parallel Computation of Similarity Metric.

    Yun-Gang Luo

    Full Text Available Neuroimage registration is crucial for brain morphometric analysis and treatment efficacy evaluation. However, existing advanced registration algorithms such as FLIRT and ANTs are not efficient enough for clinical use. In this paper, a GPU implementation of FLIRT with the correlation ratio (CR as the similarity metric and a GPU accelerated correlation coefficient (CC calculation for the symmetric diffeomorphic registration of ANTs have been developed. The comparison with their corresponding original tools shows that our accelerated algorithms can greatly outperform the original algorithm in terms of computational efficiency. This paper demonstrates the great potential of applying these registration tools in clinical applications.

  1. Distributed Efficient Similarity Search Mechanism in Wireless Sensor Networks

    Khandakar Ahmed; Gregory, Mark A.

    2015-01-01

    The Wireless Sensor Network similarity search problem has received considerable research attention due to sensor hardware imprecision and environmental parameter variations. Most of the state-of-the-art distributed data centric storage (DCS) schemes lack optimization for similarity queries of events. In this paper, a DCS scheme with metric based similarity searching (DCSMSS) is proposed. DCSMSS takes motivation from vector distance index, called iDistance, in order to transform the issue of s...

  2. Activity-relevant similarity values for fingerprints and implications for similarity searching

    Swarit Jasial; Ye Hu; Martin Vogt; Jürgen Bajorath

    2016-01-01

    A largely unsolved problem in chemoinformatics is the issue of how calculated compound similarity relates to activity similarity, which is central to many applications. In general, activity relationships are predicted from calculated similarity values. However, there is no solid scientific foundation to bridge between calculated molecular and observed activity similarity. Accordingly, the success rate of identifying new active compounds by similarity searching is limited. Although various att...

  3. How Google Web Search copes with very similar documents

    Mettrop, W.; Nieuwenhuysen, P.; Smulders, H.

    2006-01-01

    A significant portion of the computer files that carry documents, multimedia, programs etc. on the Web are identical or very similar to other files on the Web. How do search engines cope with this? Do they perform some kind of “deduplication”? How should users take into account that web search resul

  4. The search for new accelerator techniques

    The European Committee for Future Accelerators, ECFA, organized a Conference from 27-30 September under the title The Challenge of Ultra-high Energies'. The aims were to discuss possible new acceleration techniques and, if possible, to help identify the most promising and encourage further research on them. Appropriately enough this search for the new took place in the dignified setting of New College Oxford. The fact that New College is many centuries old should have helped put things in perspective

  5. Effective and Efficient Similarity Search in Scientific Workflow Repositories

    Starlinger, Johannes; Cohen-Boulakia, Sarah; Khanna, Sanjeev; Davidson, Susan; Leser, Ulf

    2015-01-01

    Scientific workflows have become a valuable tool for large-scale data processing and analysis. This has led to the creation of specialized online repositories to facilitate worflkow sharing and reuse. Over time, these repositories have grown to sizes that call for advanced methods to support workflow discovery, in particular for similarity search. Effective similarity search requires both high quality algorithms for the comparison of scientific workflows and efficient strategies for indexing,...

  6. Indexing schemes for similarity search: an illustrated paradigm

    Pestov, Vladimir; Stojmirovic, Aleksandar

    2002-01-01

    We suggest a variation of the Hellerstein--Koutsoupias--Papadimitriou indexability model for datasets equipped with a similarity measure, with the aim of better understanding the structure of indexing schemes for similarity-based search and the geometry of similarity workloads. This in particular provides a unified approach to a great variety of schemes used to index into metric spaces and facilitates their transfer to more general similarity measures such as quasi-metrics. We discuss links b...

  7. Efficient Subgraph Similarity Search on Large Probabilistic Graph Databases

    Yuan, Ye; Chen, Lei; Wang, Haixun

    2012-01-01

    Many studies have been conducted on seeking the efficient solution for subgraph similarity search over certain (deterministic) graphs due to its wide application in many fields, including bioinformatics, social network analysis, and Resource Description Framework (RDF) data management. All these works assume that the underlying data are certain. However, in reality, graphs are often noisy and uncertain due to various factors, such as errors in data extraction, inconsistencies in data integration, and privacy preserving purposes. Therefore, in this paper, we study subgraph similarity search on large probabilistic graph databases. Different from previous works assuming that edges in an uncertain graph are independent of each other, we study the uncertain graphs where edges' occurrences are correlated. We formally prove that subgraph similarity search over probabilistic graphs is #P-complete, thus, we employ a filter-and-verify framework to speed up the search. In the filtering phase,we develop tight lower and u...

  8. SEARCH PROFILES BASED ON USER TO CLUSTER SIMILARITY

    Ilija Subasic

    2007-12-01

    Full Text Available Privacy of web users' query search logs has, since last year's AOL dataset release, been treated as one of the central issues concerning privacy on the Internet, Therefore, the question of privacy preservation has also raised a lot of attention in different communities surrounding the search engines. Usage of clustering methods for providing low level contextual search, wriile retaining high privacy/utility is examined in this paper. By using only the user's cluster membership the search query terms could be no longer retained thus providing less privacy concerns both for the users and companies. The paper brings lightweight framework for combining query words, user similarities and clustering in order to provide a meaningful way of mining user searches while protecting their privacy. This differs from previous attempts for privacy preserving in the attempt to anonymize the queries instead of the users.

  9. Multiple search methods for similarity-based virtual screening: analysis of search overlap and precision

    Holliday John D; Kanoulas Evangelos; Malim Nurul; Willett Peter

    2011-01-01

    Abstract Background Data fusion methods are widely used in virtual screening, and make the implicit assumption that the more often a molecule is retrieved in multiple similarity searches, the more likely it is to be active. This paper tests the correctness of this assumption. Results Sets of 25 searches using either the same reference structure and 25 different similarity measures (similarity fusion) or 25 different reference structures and the same similarity measure (group fusion) show that...

  10. Improving spectral library search by redefining similarity measures.

    Garg, Ankita; Enright, Catherine G; Madden, Michael G

    2015-05-26

    Similarity plays a central role in spectral library search. The goal of spectral library search is to identify those spectra in a reference library of known materials that most closely match an unknown query spectrum, on the assumption that this will allow us to identify the main constituent(s) of the query spectrum. The similarity measures used for this task in software and the academic literature are almost exclusively metrics, meaning that the measures obey the three axioms of metrics: (1) minimality; (2) symmetry; (3) triangle inequality. Consequently, they implicitly assume that the query spectrum is drawn from the same distribution as that of the reference library. In this paper, we demonstrate that this assumption is not necessary in practical spectral library search and that in fact it is often violated in practice. Although the reference library may be constructed carefully, it is generally impossible to guarantee that all future query spectra will be drawn from the same distribution as the reference library. Before evaluating different similarity measures, we need to understand how they define the relationship between spectra. In spectral library search, we often aim to find the constituent(s) of a mixture. We propose that, rather than asking which reference library spectra are similar to the mixture, we should ask which of the reference library spectra are contained in the given query mixture. This question is inherently asymmetric. Therefore, we should adopt a nonmetric measure. To evaluate our hypothesis, we apply a nonmetric measure formulated by Tversky [Psychol. Rev. 1977, 84, 327-352] known as the Contrast Model and compare its performance to the well-known Jaccard similarity index metric on spectroscopic data sets. Our results show that the Tversky similarity measure yields better results than the Jaccard index. PMID:25902003

  11. A Visual Similarity-Based 3D Search Engine

    Lmaati, Elmustapha Ait; Oirrak, Ahmed El; M.N. Kaddioui

    2009-01-01

    Retrieval systems for 3D objects are required because 3D databases used around the web are growing. In this paper, we propose a visual similarity based search engine for 3D objects. The system is based on a new representation of 3D objects given by a 3D closed curve that captures all information about the surface of the 3D object. We propose a new 3D descriptor, which is a combination of three signatures of this new representation, and we implement it in our interactive web based search engin...

  12. RAPSearch: a fast protein similarity search tool for short reads

    Choi Jeong-Hyeon

    2011-05-01

    Full Text Available Abstract Background Next Generation Sequencing (NGS is producing enormous corpuses of short DNA reads, affecting emerging fields like metagenomics. Protein similarity search--a key step to achieve annotation of protein-coding genes in these short reads, and identification of their biological functions--faces daunting challenges because of the very sizes of the short read datasets. Results We developed a fast protein similarity search tool RAPSearch that utilizes a reduced amino acid alphabet and suffix array to detect seeds of flexible length. For short reads (translated in 6 frames we tested, RAPSearch achieved ~20-90 times speedup as compared to BLASTX. RAPSearch missed only a small fraction (~1.3-3.2% of BLASTX similarity hits, but it also discovered additional homologous proteins (~0.3-2.1% that BLASTX missed. By contrast, BLAT, a tool that is even slightly faster than RAPSearch, had significant loss of sensitivity as compared to RAPSearch and BLAST. Conclusions RAPSearch is implemented as open-source software and is accessible at http://omics.informatics.indiana.edu/mg/RAPSearch. It enables faster protein similarity search. The application of RAPSearch in metageomics has also been demonstrated.

  13. Online multiple kernel similarity learning for visual search.

    Xia, Hao; Hoi, Steven C H; Jin, Rong; Zhao, Peilin

    2014-03-01

    Recent years have witnessed a number of studies on distance metric learning to improve visual similarity search in content-based image retrieval (CBIR). Despite their successes, most existing methods on distance metric learning are limited in two aspects. First, they usually assume the target proximity function follows the family of Mahalanobis distances, which limits their capacity of measuring similarity of complex patterns in real applications. Second, they often cannot effectively handle the similarity measure of multimodal data that may originate from multiple resources. To overcome these limitations, this paper investigates an online kernel similarity learning framework for learning kernel-based proximity functions which goes beyond the conventional linear distance metric learning approaches. Based on the framework, we propose a novel online multiple kernel similarity (OMKS) learning method which learns a flexible nonlinear proximity function with multiple kernels to improve visual similarity search in CBIR. We evaluate the proposed technique for CBIR on a variety of image data sets in which encouraging results show that OMKS outperforms the state-of-the-art techniques significantly. PMID:24457509

  14. Similarity preserving snippet-based visualization of web search results.

    Gomez-Nieto, Erick; San Roman, Frizzi; Pagliosa, Paulo; Casaca, Wallace; Helou, Elias S; de Oliveira, Maria Cristina F; Nonato, Luis Gustavo

    2014-03-01

    Internet users are very familiar with the results of a search query displayed as a ranked list of snippets. Each textual snippet shows a content summary of the referred document (or webpage) and a link to it. This display has many advantages, for example, it affords easy navigation and is straightforward to interpret. Nonetheless, any user of search engines could possibly report some experience of disappointment with this metaphor. Indeed, it has limitations in particular situations, as it fails to provide an overview of the document collection retrieved. Moreover, depending on the nature of the query--for example, it may be too general, or ambiguous, or ill expressed--the desired information may be poorly ranked, or results may contemplate varied topics. Several search tasks would be easier if users were shown an overview of the returned documents, organized so as to reflect how related they are, content wise. We propose a visualization technique to display the results of web queries aimed at overcoming such limitations. It combines the neighborhood preservation capability of multidimensional projections with the familiar snippet-based representation by employing a multidimensional projection to derive two-dimensional layouts of the query search results that preserve text similarity relations, or neighborhoods. Similarity is computed by applying the cosine similarity over a "bag-of-words" vector representation of collection built from the snippets. If the snippets are displayed directly according to the derived layout, they will overlap considerably, producing a poor visualization. We overcome this problem by defining an energy functional that considers both the overlapping among snippets and the preservation of the neighborhood structure as given in the projected layout. Minimizing this energy functional provides a neighborhood preserving two-dimensional arrangement of the textual snippets with minimum overlap. The resulting visualization conveys both a global

  15. Computing Semantic Similarity Measure Between Words Using Web Search Engine

    Pushpa C N

    2013-05-01

    Full Text Available Semantic Similarity measures between words plays an important role in information retrieval, natural language processing and in various tasks on the web. In this paper, we have proposed a Modified Pattern Extraction Algorithm to compute th e supervised semantic similarity measure between the words by combining both page count meth od and web snippets method. Four association measures are used to find semantic simi larity between words in page count method using web search engines. We use a Sequential Minim al Optimization (SMO support vector machines (SVM to find the optimal combination of p age counts-based similarity scores and top-ranking patterns from the web snippets method. The SVM is trained to classify synonymous word-pairs and non-synonymous word-pairs. The propo sed Modified Pattern Extraction Algorithm outperforms by 89.8 percent of correlatio n value.

  16. On optimizing distance-based similarity search for biological databases.

    Mao, Rui; Xu, Weijia; Ramakrishnan, Smriti; Nuckolls, Glen; Miranker, Daniel P

    2005-01-01

    Similarity search leveraging distance-based index structures is increasingly being used for both multimedia and biological database applications. We consider distance-based indexing for three important biological data types, protein k-mers with the metric PAM model, DNA k-mers with Hamming distance and peptide fragmentation spectra with a pseudo-metric derived from cosine distance. To date, the primary driver of this research has been multimedia applications, where similarity functions are often Euclidean norms on high dimensional feature vectors. We develop results showing that the character of these biological workloads is different from multimedia workloads. In particular, they are not intrinsically very high dimensional, and deserving different optimization heuristics. Based on MVP-trees, we develop a pivot selection heuristic seeking centers and show it outperforms the most widely used corner seeking heuristic. Similarly, we develop a data partitioning approach sensitive to the actual data distribution in lieu of median splits. PMID:16447992

  17. On Fuzzy vs. Metric Similarity Search in Complex Databases

    Eckhardt, Alan; Skopal, T.; Vojtáš, Peter

    Berlin: Springer, 2009 - ( And reasen, T.; Yager, R.; Bulskov, H.; Christiansen, H.; Larsen, H.), s. 64-75. (Lecture Notes in Artificial Intelligence . 5822). ISBN 978-3-642-04956-9. ISSN 0302-9743. [FQAS 2009. International Conference on Flexible Query Answering Systems /8./. Roskilde (DK), 26.10.2009-28.10.2009] R&D Projects: GA AV ČR 1ET100300517; GA ČR GD201/09/H057 Grant ostatní: GA ČR(CZ) GA201/09/0683 Institutional research plan: CEZ:AV0Z10300504 Keywords : fuzzy operators * non-metric search * similarity search * indexing Subject RIV: IN - Informatics, Computer Science

  18. SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters

    Lefkowitz Elliot J

    2004-10-01

    Full Text Available Abstract Background Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a useful source of functional and structural information about these sequences. Using software such as the basic local alignment search tool (BLAST or HMMPFAM to identify statistically significant matches between newly sequenced segments of genetic material and those in databases is an important task for most molecular biologists. Searching algorithms are intrinsically slow and data-intensive, especially in light of the rapid growth of biological sequence databases due to the emergence of high throughput DNA sequencing techniques. Thus, traditional bioinformatics tools are impractical on PCs and even on dedicated UNIX servers. To take advantage of larger databases and more reliable methods, high performance computation becomes necessary. Results We describe the implementation of SS-Wrapper (Similarity Search Wrapper, a package of wrapper applications that can parallelize similarity search applications on a Linux cluster. Our wrapper utilizes a query segmentation-search (QS-search approach to parallelize sequence database search applications. It takes into consideration load balancing between each node on the cluster to maximize resource usage. QS-search is designed to wrap many different search tools, such as BLAST and HMMPFAM using the same interface. This implementation does not alter the original program, so newly obtained programs and program updates should be accommodated easily. Benchmark experiments using QS-search to optimize BLAST and HMMPFAM showed that QS-search accelerated the performance of these programs almost linearly in proportion to the number of CPUs used. We have also implemented a wrapper that utilizes a database segmentation approach (DS-BLAST that provides a complementary solution for BLAST searches when the database is too large to fit into

  19. SHOP: scaffold hopping by GRID-based similarity searches

    Bergmann, Rikke; Linusson, Anna; Zamora, Ismael

    2007-01-01

    A new GRID-based method for scaffold hopping (SHOP) is presented. In a fully automatic manner, scaffolds were identified in a database based on three types of 3D-descriptors. SHOP's ability to recover scaffolds was assessed and validated by searching a database spiked with fragments of known...... scaffolds were in the 31 top-ranked scaffolds. SHOP also identified new scaffolds with substantially different chemotypes from the queries. Docking analysis indicated that the new scaffolds would have similar binding modes to those of the respective query scaffolds observed in X-ray structures. The...

  20. Quick and easy implementation of approximate similarity search with Lucene

    Amato, Giuseppe; Bolettieri, Paolo; Gennaro, Claudio; Rabitti, Fausto

    2013-01-01

    Similarity search technique has been proved to be an effective way for retrieving multimedia content. However, as the amount of available multimedia data increases, the cost of developing from scratch a robust and scalable system with content-based image retrieval facilities is quite prohibitive. In this paper, we propose to exploit an approach that allows us to convert low level features into a textual form. In this way, we are able to easily set up a retrieval system on top of the Lucene se...

  1. Rank-Based Similarity Search: Reducing the Dimensional Dependence.

    Houle, Michael E; Nett, Michael

    2015-01-01

    This paper introduces a data structure for k-NN search, the Rank Cover Tree (RCT), whose pruning tests rely solely on the comparison of similarity values; other properties of the underlying space, such as the triangle inequality, are not employed. Objects are selected according to their ranks with respect to the query object, allowing much tighter control on the overall execution costs. A formal theoretical analysis shows that with very high probability, the RCT returns a correct query result in time that depends very competitively on a measure of the intrinsic dimensionality of the data set. The experimental results for the RCT show that non-metric pruning strategies for similarity search can be practical even when the representational dimension of the data is extremely high. They also show that the RCT is capable of meeting or exceeding the level of performance of state-of-the-art methods that make use of metric pruning or other selection tests involving numerical constraints on distance values. PMID:26353214

  2. Activity-relevant similarity values for fingerprints and implications for similarity searching [version 1; referees: 3 approved

    Swarit Jasial

    2016-04-01

    Full Text Available A largely unsolved problem in chemoinformatics is the issue of how calculated compound similarity relates to activity similarity, which is central to many applications. In general, activity relationships are predicted from calculated similarity values. However, there is no solid scientific foundation to bridge between calculated molecular and observed activity similarity. Accordingly, the success rate of identifying new active compounds by similarity searching is limited. Although various attempts have been made to establish relationships between calculated fingerprint similarity values and biological activities, none of these has yielded generally applicable rules for similarity searching. In this study, we have addressed the question of molecular versus activity similarity in a more fundamental way. First, we have evaluated if activity-relevant similarity value ranges could in principle be identified for standard fingerprints and distinguished from similarity resulting from random compound comparisons. Then, we have analyzed if activity-relevant similarity values could be used to guide typical similarity search calculations aiming to identify active compounds in databases. It was found that activity-relevant similarity values can be identified as a characteristic feature of fingerprints. However, it was also shown that such values cannot be reliably used as thresholds for practical similarity search calculations. In addition, the analysis presented herein helped to rationalize differences in fingerprint search performance.

  3. Future short-baseline sterile neutrino searches with accelerators

    A number of experimental anomalies in neutrino oscillation physics point to the existence of at least one light sterile neutrino. This hypothesis can be precisely tested using neutrinos from reactors, radioactive isotopes, and particle accelerators. The focus of these proceedings is on future dedicated short-baseline sterile neutrino searches using accelerators

  4. Activity-relevant similarity values for fingerprints and implications for similarity searching [version 2; referees: 3 approved

    Swarit Jasial; Ye Hu; Martin Vogt; Jürgen Bajorath

    2016-01-01

    A largely unsolved problem in chemoinformatics is the issue of how calculated compound similarity relates to activity similarity, which is central to many applications. In general, activity relationships are predicted from calculated similarity values. However, there is no solid scientific foundation to bridge between calculated molecular and observed activity similarity. Accordingly, the success rate of identifying new active compounds by similarity searching is limited. Although various att...

  5. Dark Matter Searches at Accelerator Facilities

    Dutta, Bhaskar

    2014-01-01

    About 80 percent of the matter content of the universe is dark matter. However, the particle origin of dark matter is yet to be established. Many extensions of the Standard Model (SM) contain candidates of dark matter. The search for the particle origin is currently ongoing at the large hadron collider (LHC). In this review, I will summarize the different search strategies for this elusive particle.

  6. Similarity between Grover's quantum search algorithm and classical two-body collisions

    Zhang, Jingfu; Lu, Zhiheng

    2001-01-01

    By studying the attribute of the inversion about average operation in quantum searching algorithm, we find the similarity between the quantum searching and the course of two rigid bodies'collision. Some related questions are discussed from this similarity.

  7. Cosmic ray acceleration search in Supernova Remnants

    Galactic Supernova Remnants (SNRs) are among the best candidates as source of cosmic rays due to energetics, observed rate of explosion and as possible sites where the Fermi mechanisms naturally plays a key role. Evidence of hadronic acceleration processes taking place in SNRs are being collected with the Fermi-LAT, whose sensitivity in the range 100MeV–100GeV is crucial for disentangling possible hadronic contribution from inverse Compton or bremsstrahlung leptonic component. A survey of the detected SNRs will be given, focusing the attention on the role of the environment and the evolution stage of the SNR in the interpretation of the observed γ-ray spectra

  8. Cosmic ray acceleration search in Supernova Remnants

    Giordano, Francesco; Di Venere, Leonardo [Dipartimento di Fisica M. Merlin dell' Università e del Politecnico di Bari, I-70126 Bari (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, I-70126 Bari (Italy)

    2014-11-15

    Galactic Supernova Remnants (SNRs) are among the best candidates as source of cosmic rays due to energetics, observed rate of explosion and as possible sites where the Fermi mechanisms naturally plays a key role. Evidence of hadronic acceleration processes taking place in SNRs are being collected with the Fermi-LAT, whose sensitivity in the range 100MeV–100GeV is crucial for disentangling possible hadronic contribution from inverse Compton or bremsstrahlung leptonic component. A survey of the detected SNRs will be given, focusing the attention on the role of the environment and the evolution stage of the SNR in the interpretation of the observed γ-ray spectra.

  9. Astrophysical search strategies for accelerator blind dark matter

    Wells, James D.

    1998-01-01

    A weakly interacting dark-matter particle may be difficult to discover at an accelerator because it either (1) is too massive, (2) has no standard-model gauge interactions, or (3) is almost degenerate with other states. In each of these cases, searches for annihilation products in the Galactic halo are useful probes of dark-matter properties. Using the example of supersymmetric dark matter, I discuss how astrophysical searches for dark matter may provide discovery and mass information inacces...

  10. Gene expression module-based chemical function similarity search

    Li, Yun; Hao, Pei; Zheng, Siyuan; Tu, Kang; Fan, Haiwei; Zhu, Ruixin; Ding, Guohui; Dong, Changzheng; Wang, Chuan; Li, Xuan; Thiesen, H.-J.; Chen, Y. Eugene; Jiang, HuaLiang; Liu, Lei; Li, Yixue

    2008-01-01

    Investigation of biological processes using selective chemical interventions is generally applied in biomedical research and drug discovery. Many studies of this kind make use of gene expression experiments to explore cellular responses to chemical interventions. Recently, some research groups constructed libraries of chemical related expression profiles, and introduced similarity comparison into chemical induced transcriptome analysis. Resembling sequence similarity alignment, expression pat...

  11. Cognitive Residues of Similarity: 'After-Effects' of Similarity Computations in Visual Search

    O'Toole, Stephanie; Keane, Mark T.

    2013-01-01

    What are the 'cognitive after-effects' of making a similarity judgement? What, cognitively, is left behind and what effect might these residues have on subsequent processing? In this paper, we probe for such after-effects using a visual searcht ask, performed after a task in which pictures of real-world objects were compared. So, target objects were first presented in a comparison task (e.g., rate the similarity of this object to another) thus, presumably, modifying some of their features bef...

  12. G-Hash: Towards Fast Kernel-based Similarity Search in Large Graph Databases

    Wang, Xiaohong; Smalter, Aaron; Huan, Jun; Lushington, Gerald H.

    2009-01-01

    Structured data including sets, sequences, trees and graphs, pose significant challenges to fundamental aspects of data management such as efficient storage, indexing, and similarity search. With the fast accumulation of graph databases, similarity search in graph databases has emerged as an important research topic. Graph similarity search has applications in a wide range of domains including cheminformatics, bioinformatics, sensor network management, social network management, and XML docum...

  13. Ranking and clustering of search results: Analysis of Similarity graph

    Shevchuk, Ksenia Alexander

    2008-01-01

    Evaluate the clustering of the similarity matrix and confirm that it is high. Compare the ranking results of the eigenvector ranking and the Link Popularity ranking and confirm for the high clustered graph the correlation between those is larger than for the low clustered graph.

  14. Density-based similarity measures for content based search

    Hush, Don R [Los Alamos National Laboratory; Porter, Reid B [Los Alamos National Laboratory; Ruggiero, Christy E [Los Alamos National Laboratory

    2009-01-01

    We consider the query by multiple example problem where the goal is to identify database samples whose content is similar to a coUection of query samples. To assess the similarity we use a relative content density which quantifies the relative concentration of the query distribution to the database distribution. If the database distribution is a mixture of the query distribution and a background distribution then it can be shown that database samples whose relative content density is greater than a particular threshold {rho} are more likely to have been generated by the query distribution than the background distribution. We describe an algorithm for predicting samples with relative content density greater than {rho} that is computationally efficient and possesses strong performance guarantees. We also show empirical results for applications in computer network monitoring and image segmentation.

  15. Feasibility of new particle search at future light source accelerators

    Various types of accelerators are proposed as a future light source. Especially those design which can produce high peak power at high repetition rate utilizing energy recovery scheme are interesting also for searching a new particle which couples with photons. We estimated sensitivity of axion search with future XFEL-O, EUV-FEL, and LCSS-γ machines. It shows experiment at these machines can extend the parameter space. We also checked the feasibility of FEL output power assumed in this discussion. (author)

  16. Perceptual Grouping in Haptic Search: The Influence of Proximity, Similarity, and Good Continuation

    Overvliet, Krista E.; Krampe, Ralf Th.; Wagemans, Johan

    2012-01-01

    We conducted a haptic search experiment to investigate the influence of the Gestalt principles of proximity, similarity, and good continuation. We expected faster search when the distractors could be grouped. We chose edges at different orientations as stimuli because they are processed similarly in the haptic and visual modality. We therefore…

  17. Improving image similarity search effectiveness in a multimedia content management system

    Amato, Giuseppe; Falchi, Fabrizio; Gennaro, Claudio; Rabitti, Fausto; Savino, Pasquale; Stanchev, Peter

    2004-01-01

    In this paper, a technique for making more effective the similarity search process of images in a Multimedia Content Management System is proposed. The content-based retrieval process integrates the search on different multimedia components, linked in XML structures. Depending on the specific characteristics of an image data set, some features can be more effective than others when performing similarity search. Starting from this observation, we propose a technique that predicts the effective...

  18. On a Probabilistic Approach to Determining the Similarity between Boolean Search Request Formulations.

    Radecki, Tadeusz

    1982-01-01

    Presents and discusses the results of research into similarity measures for search request formulations which employ Boolean combinations of index terms. The use of a weighting mechanism to indicate the importance of attributes in a search formulation is described. A 16-item reference list is included. (JL)

  19. Comparative study on Authenticated Sub Graph Similarity Search in Outsourced Graph Database

    N. D. Dhamale; Prof. S. R. Durugkar

    2015-01-01

    Today security is very important in the database system. Advanced database systems face a great challenge raised by the emergence of massive, complex structural data in bioinformatics, chem-informatics, and many other applications. Since exact matching is often too restrictive, similarity search of complex structures becomes a vital operation that must be supported efficiently. The Subgraph similarity search is used in graph databases to retrieve graphs whose subgraphs...

  20. Effects of Part-based Similarity on Visual Search: The Frankenbear Experiment

    Alexander, Robert G.; Zelinsky, Gregory J.

    2012-01-01

    Do the target-distractor and distractor-distractor similarity relationships known to exist for simple stimuli extend to real-world objects, and are these effects expressed in search guidance or target verification? Parts of photorealistic distractors were replaced with target parts to create four levels of target-distractor similarity under heterogenous and homogenous conditions. We found that increasing target-distractor similarity and decreasing distractor-distractor similarity impaired sea...

  1. A Theoretical Framework for Defining Similarity Measures for Boolean Search Request Formulations, Including Some Experimental Results.

    Radecki, Tadeusz

    1985-01-01

    Reports research results into a methodology for determining similarity between queries characterized by Boolean search request formulations and discusses similarity measures for Boolean combinations of index terms. Rationale behind these measures is outlined, and conditions ensuring their equivalence are identified. Results of an experiment…

  2. SAPIR - Executing complex similarity queries over multi layer P2P search structures

    Falchi, Fabrizio; Batko, Michal

    2009-01-01

    This deliverable reports the activities conducted within Task 5.4 "Executing complex similarity queries over multi layer P2P search structures" of the SAPIR project. In particular the deliverable discusses complex similarity queries issues and the implementation of the query processing over the P2P indexing. The document is accompanied by a zip file containing the javadoc for MUFIN.

  3. MEASURING THE PERFORMANCE OF SIMILARITY PROPAGATION IN AN SEMANTIC SEARCH ENGINE

    S. K. Jayanthi

    2013-10-01

    Full Text Available In the current scenario, web page result personalization is playing a vital role. Nearly 80 % of the users expect the best results in the first page itself without having any persistence to browse longer in URL mode. This research work focuses on two main themes: Semantic web search through online and Domain based search through offline. The first part is to find an effective method which allows grouping similar results together using BookShelf Data Structure and organizing the various clusters. The second one is focused on the academic domain based search through offline. This paper focuses on finding documents which are similar and how Vector space can be used to solve it. So more weightage is given for the principles and working methodology of similarity propagation. Cosine similarity measure is used for finding the relevancy among the documents.

  4. Comparative study on Authenticated Sub Graph Similarity Search in Outsourced Graph Database

    N. D. Dhamale

    2015-11-01

    Full Text Available Today security is very important in the database system. Advanced database systems face a great challenge raised by the emergence of massive, complex structural data in bioinformatics, chem-informatics, and many other applications. Since exact matching is often too restrictive, similarity search of complex structures becomes a vital operation that must be supported efficiently. The Subgraph similarity search is used in graph databases to retrieve graphs whose subgraphs are similar to a given query graph. It has been proven successful in a wide range of applications including bioinformatics and chem-informatics, etc. Due to the cost of providing efficient similarity search services on everincreasing graph data, database outsourcing is apparently an appealing solution to database owners. In this paper, we are studying on authentication techniques that follow the popular filtering-and-verification framework. An authentication-friendly metric index called GMTree. Specifically, we transform the similarity search into a search in a graph metric space and derive small verification objects (VOs to-be-transmitted to query clients. To further optimize GMTree, we are studying on a sampling-based pivot selection method and an authenticated version of MCS computation.

  5. Efficient Retrieval of Images for Search Engine by Visual Similarity and Re Ranking

    Viswa S S

    2013-06-01

    Full Text Available Nowadays, web scale image search engines (e.g. Google Image Search, Microsoft Live Image Search rely almost purely on surrounding text features. Users type keywords in hope of finding a certain type of images. The search engine returns thousands of images ranked by the text keywords extracted from the surrounding text. However, many of returned images are noisy, disorganized, or irrelevant. Even Google and Microsoft have no Visual Information for searching of images. Using visual information to re rank and improve text based image search results is the idea. This improves the precision of the text based image search ranking by incorporating the information conveyed by the visual modality. The typical assumption that the top- images in the text-based search result are equally relevant is relaxed by linking the relevance of the images to their initial rank positions. Then, a number of images from the initial search result are employed as the prototypes that serve to visually represent the query and that are subsequently used to construct meta re rankers .i.e. The most relevant images are found by visual similarity and the average scores are calculated. By applying different meta re rankers to an image from the initial result, re ranking scores are generated, which are then used to find the new rank position for an image in the re ranked search result. Human supervision is introduced to learn the model weights offline, prior to the online re ranking process. While model learning requires manual labelling of the results for a few queries, the resulting model is query independent and therefore applicable to any other query. The experimental results on a representative web image search dataset comprising 353 queries demonstrate that the proposed method outperforms the existing supervised and unsupervised Re ranking approaches. Moreover, it improves the performance over the text-based image search engine by more than 25.48%.

  6. Improving protein structure similarity searches using domain boundaries based on conserved sequence information

    Madej Tom; Wang Yanli; Thompson Kenneth; Bryant Stephen H

    2009-01-01

    Abstract Background The identification of protein domains plays an important role in protein structure comparison. Domain query size and composition are critical to structure similarity search algorithms such as the Vector Alignment Search Tool (VAST), the method employed for computing related protein structures in NCBI Entrez system. Currently, domains identified on the basis of structural compactness are used for VAST computations. In this study, we have investigated how alternative definit...

  7. A comparison of field-based similarity searching methods: CatShape, FBSS, and ROCS.

    Moffat, Kirstin; Gillet, Valerie J; Whittle, Martin; Bravi, Gianpaolo; Leach, Andrew R

    2008-04-01

    Three field-based similarity methods are compared in retrospective virtual screening experiments. The methods are the CatShape module of CATALYST, ROCS, and an in-house program developed at the University of Sheffield called FBSS. The programs are used in both rigid and flexible searches carried out in the MDL Drug Data Report. UNITY 2D fingerprints are also used to provide a comparison with a more traditional approach to similarity searching, and similarity based on simple whole-molecule properties is used to provide a baseline for the more sophisticated searches. Overall, UNITY 2D fingerprints and ROCS with the chemical force field option gave comparable performance and were superior to the shape-only 3D methods. When the flexible methods were compared with the rigid methods, it was generally found that the flexible methods gave slightly better results than their respective rigid methods; however, the increased performance did not justify the additional computational cost required. PMID:18351728

  8. Accelerated Search for Gaussian Generator Based on Triple Prime Integers

    Boris S. Verkhovsky

    2009-01-01

    Full Text Available Problem statement: Modern cryptographic algorithms are based on complexity of two problems: Integer factorization of real integers and a Discrete Logarithm Problem (DLP. Approach: The latter problem is even more complicated in the domain of complex integers, where Public Key Cryptosystems (PKC had an advantage over analogous encryption-decryption protocols in arithmetic of real integers modulo p: The former PKC have quadratic cycles of order O (p2 while the latter PKC had linear cycles of order O(p. Results: An accelerated non-deterministic search algorithm for a primitive root (generator in a domain of complex integers modulo triple prime p was provided in this study. It showed the properties of triple primes, the frequencies of their occurrence on a specified interval and analyzed the efficiency of the proposed algorithm. Conclusion: Numerous computer experiments and their analysis indicated that three trials were sufficient on average to find a Gaussian generator.

  9. Global search acceleration in the nested optimization scheme

    Grishagin, Vladimir A.; Israfilov, Ruslan A.

    2016-06-01

    Multidimensional unconstrained global optimization problem with objective function under Lipschitz condition is considered. For solving this problem the dimensionality reduction approach on the base of the nested optimization scheme is used. This scheme reduces initial multidimensional problem to a family of one-dimensional subproblems being Lipschitzian as well and thus allows applying univariate methods for the execution of multidimensional optimization. For two well-known one-dimensional methods of Lipschitz optimization the modifications providing the acceleration of the search process in the situation when the objective function is continuously differentiable in a vicinity of the global minimum are considered and compared. Results of computational experiments on conventional test class of multiextremal functions confirm efficiency of the modified methods.

  10. Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity

    Petitjean Michel

    2009-08-01

    Full Text Available Abstract Background Virtual screening methods are now well established as effective to identify hit and lead candidates and are fully integrated in most drug discovery programs. Ligand-based approaches make use of physico-chemical, structural and energetics properties of known active compounds to search large chemical libraries for related and novel chemotypes. While 2D-similarity search tools are known to be fast and efficient, the use of 3D-similarity search methods can be very valuable to many research projects as integration of "3D knowledge" can facilitate the identification of not only related molecules but also of chemicals possessing distant scaffolds as compared to the query and therefore be more inclined to scaffolds hopping. To date, very few methods performing this task are easily available to the scientific community. Results We introduce a new approach (LigCSRre to the 3D ligand similarity search of drug candidates. It combines a 3D maximum common substructure search algorithm independent on atom order with a tunable description of atomic compatibilities to prune the search and increase its physico-chemical relevance. We show, on 47 experimentally validated active compounds across five protein targets having different specificities, that for single compound search, the approach is able to recover on average 52% of the co-actives in the top 1% of the ranked list which is better than gold standards of the field. Moreover, the combination of several runs on a single protein target using different query active compounds shows a remarkable improvement in enrichment. Such Results demonstrate LigCSRre as a valuable tool for ligand-based screening. Conclusion LigCSRre constitutes a new efficient and generic approach to the 3D similarity screening of small compounds, whose flexible design opens the door to many enhancements. The program is freely available to the academics for non-profit research at: http://bioserv.rpbs.univ-paris-diderot.fr/LigCSRre.html.

  11. Accelerated search for materials with targeted properties by adaptive design

    Xue, Dezhen; Balachandran, Prasanna V.; Hogden, John; Theiler, James; Xue, Deqing; Lookman, Turab

    2016-04-01

    Finding new materials with targeted properties has traditionally been guided by intuition, and trial and error. With increasing chemical complexity, the combinatorial possibilities are too large for an Edisonian approach to be practical. Here we show how an adaptive design strategy, tightly coupled with experiments, can accelerate the discovery process by sequentially identifying the next experiments or calculations, to effectively navigate the complex search space. Our strategy uses inference and global optimization to balance the trade-off between exploitation and exploration of the search space. We demonstrate this by finding very low thermal hysteresis (ΔT) NiTi-based shape memory alloys, with Ti50.0Ni46.7Cu0.8Fe2.3Pd0.2 possessing the smallest ΔT (1.84 K). We synthesize and characterize 36 predicted compositions (9 feedback loops) from a potential space of ~800,000 compositions. Of these, 14 had smaller ΔT than any of the 22 in the original data set.

  12. Similarity-based search of model organism, disease and drug effect phenotypes

    Hoehndorf, Robert

    2015-02-19

    Background: Semantic similarity measures over phenotype ontologies have been demonstrated to provide a powerful approach for the analysis of model organism phenotypes, the discovery of animal models of human disease, novel pathways, gene functions, druggable therapeutic targets, and determination of pathogenicity. Results: We have developed PhenomeNET 2, a system that enables similarity-based searches over a large repository of phenotypes in real-time. It can be used to identify strains of model organisms that are phenotypically similar to human patients, diseases that are phenotypically similar to model organism phenotypes, or drug effect profiles that are similar to the phenotypes observed in a patient or model organism. PhenomeNET 2 is available at http://aber-owl.net/phenomenet. Conclusions: Phenotype-similarity searches can provide a powerful tool for the discovery and investigation of molecular mechanisms underlying an observed phenotypic manifestation. PhenomeNET 2 facilitates user-defined similarity searches and allows researchers to analyze their data within a large repository of human, mouse and rat phenotypes.

  13. An efficient similarity search based on indexing in large DNA databases.

    Jeong, In-Seon; Park, Kyoung-Wook; Kang, Seung-Ho; Lim, Hyeong-Seok

    2010-04-01

    Index-based search algorithms are an important part of a genomic search, and how to construct indices is the key to an index-based search algorithm to compute similarities between two DNA sequences. In this paper, we propose an efficient query processing method that uses special transformations to construct an index. It uses small storage and it rapidly finds the similarity between two sequences in a DNA sequence database. At first, a sequence is partitioned into equal length windows. We select the likely subsequences by computing Hamming distance to query sequence. The algorithm then transforms the subsequences in each window into a multidimensional vector space by indexing the frequencies of the characters, including the positional information of the characters in the subsequences. The result of our experiments shows that the algorithm has faster run time than other heuristic algorithms based on index structure. Also, the algorithm is as accurate as those heuristic algorithms. PMID:20418167

  14. Twin Similarities in Holland Types as Shown by Scores on the Self-Directed Search

    Chauvin, Ida; McDaniel, Janelle R.; Miller, Mark J.; King, James M.; Eddlemon, Ondie L. M.

    2012-01-01

    This study examined the degree of similarity between scores on the Self-Directed Search from one set of identical twins. Predictably, a high congruence score was found. Results from a biographical sheet are discussed as well as implications of the results for career counselors.

  15. Similarity and heterogeneity effects in visual search are mediated by "segmentability".

    Utochkin, Igor S; Yurevich, Maria A

    2016-07-01

    The heterogeneity of our visual environment typically reduces the speed with which a singleton target can be found. Visual search theories explain this phenomenon via nontarget similarities and dissimilarities that affect grouping, perceptual noise, and so forth. In this study, we show that increasing the heterogeneity of a display can facilitate rather than inhibit visual search for size and orientation singletons when heterogeneous features smoothly fill the transition between highly distinguishable nontargets. We suggest that this smooth transition reduces the "segmentability" of dissimilar items to otherwise separate subsets, causing the visual system to treat them as a near-homogenous set standing apart from a singleton. (PsycINFO Database Record PMID:26784002

  16. Manifold Learning for Multivariate Variable-Length Sequences With an Application to Similarity Search.

    Ho, Shen-Shyang; Dai, Peng; Rudzicz, Frank

    2016-06-01

    Multivariate variable-length sequence data are becoming ubiquitous with the technological advancement in mobile devices and sensor networks. Such data are difficult to compare, visualize, and analyze due to the nonmetric nature of data sequence similarity measures. In this paper, we propose a general manifold learning framework for arbitrary-length multivariate data sequences driven by similarity/distance (parameter) learning in both the original data sequence space and the learned manifold. Our proposed algorithm transforms the data sequences in a nonmetric data sequence space into feature vectors in a manifold that preserves the data sequence space structure. In particular, the feature vectors in the manifold representing similar data sequences remain close to one another and far from the feature points corresponding to dissimilar data sequences. To achieve this objective, we assume a semisupervised setting where we have knowledge about whether some of data sequences are similar or dissimilar, called the instance-level constraints. Using this information, one learns the similarity measure for the data sequence space and the distance measures for the manifold. Moreover, we describe an approach to handle the similarity search problem given user-defined instance level constraints in the learned manifold using a consensus voting scheme. Experimental results on both synthetic data and real tropical cyclone sequence data are presented to demonstrate the feasibility of our manifold learning framework and the robustness of performing similarity search in the learned manifold. PMID:25781959

  17. Accelerated optimization problem search using Bose-Einstein condensation

    We investigate a computational device that harnesses the effects of Bose-Einstein condensation to accelerate the speed of finding the solution of optimization problems. Many computationally difficult problems, including NP-complete problems, can be formulated as a ground state search problem. In a Bose-Einstein condensate, below the critical temperature, bosonic particles have a natural tendency to accumulate in the ground state. Furthermore, the speed of attaining this configuration is enhanced as a result of final state stimulation. We propose a physical device that incorporates these basic properties of bosons into the optimization problem, such that an optimized solution is found by a simple cooling of the physical temperature of the device. Using a semiclassical model to calculate the equilibration time for reaching the ground state, we found that this can be sped up by a factor of N, where N is the boson number per site. This allows for the annealing times for reaching a particular error to be systematically decreased by increasing the boson number per site. (paper)

  18. Wikipedia Chemical Structure Explorer: substructure and similarity searching of molecules from Wikipedia

    Ertl, Peter; Patiny, Luc; Sander, Thomas; Rufener, Christian; Zasso, Michaël

    2015-01-01

    Background Wikipedia, the world’s largest and most popular encyclopedia is an indispensable source of chemistry information. It contains among others also entries for over 15,000 chemicals including metabolites, drugs, agrochemicals and industrial chemicals. To provide an easy access to this wealth of information we decided to develop a substructure and similarity search tool for chemical structures referenced in Wikipedia. Results We extracted chemical structures from entries in Wikipedia an...

  19. Target enhanced 2D similarity search by using explicit biological activity annotations and profiles

    Yu, Xiang; Geer, Lewis Y.; Han, Lianyi; Bryant, Stephen H

    2015-01-01

    Background The enriched biological activity information of compounds in large and freely-accessible chemical databases like the PubChem Bioassay Database has become a powerful research resource for the scientific research community. Currently, 2D fingerprint based conventional similarity search (CSS) is the most common widely used approach for database screening, but it does not typically incorporate the relative importance of fingerprint bits to biological activity. Results In this study, a ...

  20. Protein similarity search with subset seeds on a dedicated reconfigurable hardware

    Peterlongo, Pierre; Noé, Laurent; Lavenier, Dominique; Georges, Gilles; Jacques, Julien; Kucherov, Gregory; Giraud, Mathieu

    2007-01-01

    Genome sequencing of numerous species raises the need of complete genome comparison with precise and fast similarity searches. Today, advanced seed-based techniques (spaced seeds, multiple seeds, subset seeds) provide better sensitivity/specificity ratios. We present an implementation of such a seed-based technique onto parallel specialized hardware embedding reconfigurable architecture (FPGA), where the FPGA is tightly connected to large capacity Flash memories. This parallel system allows l...

  1. Efficient Similarity Search Using the Earth Mover's Distance for Large Multimedia Databases

    Assent, Ira; Wichterich, Marc; Meisen, Tobias;

    2008-01-01

    Multimedia similarity search in large databases requires efficient query processing. The Earth mover's distance, introduced in computer vision, is successfully used as a similarity model in a number of small-scale applications. Its computational complexity hindered its adoption in large multimedia...... databases. We enable directly indexing the Earth mover's distance in structures such as the R-tree and the VA-file by providing the accurate 'MinDist' function to any bounding rectangle in the index. We exploit the computational structure of the new MinDist to derive a new lower bound for the EMD Min...

  2. Database searching for compounds with similar biological activity using short binary bit string representations of molecules.

    Xue, L; Godden, J W; Bajorath, J

    1999-01-01

    In an effort to identify biologically active molecules in compound databases, we have investigated similarity searching using short binary bit strings with a maximum of 54 bit positions. These "minifingerprints" (MFPs) were designed to account for the presence or absence of structural fragments and/or aromatic character, flexibility, and hydrogen-bonding capacity of molecules. MFP design was based on an analysis of distributions of molecular descriptors and structural fragments in two large compound collections. The performance of different MFPs and a reference fingerprint was tested by systematic "one-against-all" similarity searches of molecules in a database containing 364 compounds with different biological activities. For each fingerprint, the most effective similarity cutoff value was determined. An MFP accounting for only 32 structural fragments showed less than 2% false positive similarity matches and correctly assigned on average approximately 40% of the compounds with the same biological activity to a query molecule. Inclusion of three numerical two-dimensional (2D) molecular descriptors increased the performance by 15%. This MFP performed better than a complex 2D fingerprint. At a similarity cutoff value of 0.85, the 2D fingerprint totally eliminated false positives but recognized less than 10% of the compounds within the same activity class. PMID:10529986

  3. WEB SEARCH ENGINE BASED SEMANTIC SIMILARITY MEASURE BETWEEN WORDS USING PATTERN RETRIEVAL ALGORITHM

    Pushpa C N

    2013-02-01

    Full Text Available Semantic Similarity measures plays an important role in information retrieval, natural language processing and various tasks on web such as relation extraction, community mining, document clustering, and automatic meta-data extraction. In this paper, we have proposed a Pattern Retrieval Algorithm [PRA] to compute the semantic similarity measure between the words by combining both page count method and web snippets method. Four association measures are used to find semantic similarity between words in page count method using web search engines. We use a Sequential Minimal Optimization (SMO support vector machines (SVM to find the optimal combination of page counts-based similarity scores and top-ranking patterns from the web snippets method. The SVM is trained to classify synonymous word-pairs and nonsynonymous word-pairs. The proposed approach aims to improve the Correlation values, Precision, Recall, and F-measures, compared to the existing methods. The proposed algorithm outperforms by 89.8 % of correlation value.

  4. Similarity-regulation of OS-EM for accelerated SPECT reconstruction

    Vaissier, P. E. B.; Beekman, F. J.; Goorden, M. C.

    2016-06-01

    Ordered subsets expectation maximization (OS-EM) is widely used to accelerate image reconstruction in single photon emission computed tomography (SPECT). Speedup of OS-EM over maximum likelihood expectation maximization (ML-EM) is close to the number of subsets used. Although a high number of subsets can shorten reconstruction times significantly, it can also cause severe image artifacts such as improper erasure of reconstructed activity if projections contain few counts. We recently showed that such artifacts can be prevented by using a count-regulated OS-EM (CR-OS-EM) algorithm which automatically adapts the number of subsets for each voxel based on the estimated number of counts that the voxel contributed to the projections. While CR-OS-EM reached high speed-up over ML-EM in high-activity regions of images, speed in low-activity regions could still be very slow. In this work we propose similarity-regulated OS-EM (SR-OS-EM) as a much faster alternative to CR-OS-EM. SR-OS-EM also automatically and locally adapts the number of subsets, but it uses a different criterion for subset regulation: the number of subsets that is used for updating an individual voxel depends on how similar the reconstruction algorithm would update the estimated activity in that voxel with different subsets. Reconstructions of an image quality phantom and in vivo scans show that SR-OS-EM retains all of the favorable properties of CR-OS-EM, while reconstruction speed can be up to an order of magnitude higher in low-activity regions. Moreover our results suggest that SR-OS-EM can be operated with identical reconstruction parameters (including the number of iterations) for a wide range of count levels, which can be an additional advantage from a user perspective since users would only have to post-filter an image to present it at an appropriate noise level.

  5. Accelerating chemical database searching using graphics processing units.

    Liu, Pu; Agrafiotis, Dimitris K; Rassokhin, Dmitrii N; Yang, Eric

    2011-08-22

    The utility of chemoinformatics systems depends on the accurate computer representation and efficient manipulation of chemical compounds. In such systems, a small molecule is often digitized as a large fingerprint vector, where each element indicates the presence/absence or the number of occurrences of a particular structural feature. Since in theory the number of unique features can be exceedingly large, these fingerprint vectors are usually folded into much shorter ones using hashing and modulo operations, allowing fast "in-memory" manipulation and comparison of molecules. There is increasing evidence that lossless fingerprints can substantially improve retrieval performance in chemical database searching (substructure or similarity), which have led to the development of several lossless fingerprint compression algorithms. However, any gains in storage and retrieval afforded by compression need to be weighed against the extra computational burden required for decompression before these fingerprints can be compared. Here we demonstrate that graphics processing units (GPU) can greatly alleviate this problem, enabling the practical application of lossless fingerprints on large databases. More specifically, we show that, with the help of a ~$500 ordinary video card, the entire PubChem database of ~32 million compounds can be searched in ~0.2-2 s on average, which is 2 orders of magnitude faster than a conventional CPU. If multiple query patterns are processed in batch, the speedup is even more dramatic (less than 0.02-0.2 s/query for 1000 queries). In the present study, we use the Elias gamma compression algorithm, which results in a compression ratio as high as 0.097. PMID:21696144

  6. Accelerator searches for new physics in the context of dark matter

    Lowette, Steven

    2016-05-01

    A review is given of the current status of searches for dark matter at accelerators. Particular emphasis is put on generic searches for direct production of dark matter at the LHC during its first run, and on the recent developments for the interpretation of the results, where the models using an effective field theory approach are now being complemented with more generic interpretations in the context of simplified models. Furthermore, results are reported briefly for searches for dark matter at the LHC in the context of supersymmetry, as well as for non-LHC accelerator searches.

  7. Semantic similarity measures in the biomedical domain by leveraging a web search engine.

    Hsieh, Sheau-Ling; Chang, Wen-Yung; Chen, Chi-Huang; Weng, Yung-Ching

    2013-07-01

    Various researches in web related semantic similarity measures have been deployed. However, measuring semantic similarity between two terms remains a challenging task. The traditional ontology-based methodologies have a limitation that both concepts must be resided in the same ontology tree(s). Unfortunately, in practice, the assumption is not always applicable. On the other hand, if the corpus is sufficiently adequate, the corpus-based methodologies can overcome the limitation. Now, the web is a continuous and enormous growth corpus. Therefore, a method of estimating semantic similarity is proposed via exploiting the page counts of two biomedical concepts returned by Google AJAX web search engine. The features are extracted as the co-occurrence patterns of two given terms P and Q, by querying P, Q, as well as P AND Q, and the web search hit counts of the defined lexico-syntactic patterns. These similarity scores of different patterns are evaluated, by adapting support vector machines for classification, to leverage the robustness of semantic similarity measures. Experimental results validating against two datasets: dataset 1 provided by A. Hliaoutakis; dataset 2 provided by T. Pedersen, are presented and discussed. In dataset 1, the proposed approach achieves the best correlation coefficient (0.802) under SNOMED-CT. In dataset 2, the proposed method obtains the best correlation coefficient (SNOMED-CT: 0.705; MeSH: 0.723) with physician scores comparing with measures of other methods. However, the correlation coefficients (SNOMED-CT: 0.496; MeSH: 0.539) with coder scores received opposite outcomes. In conclusion, the semantic similarity findings of the proposed method are close to those of physicians' ratings. Furthermore, the study provides a cornerstone investigation for extracting fully relevant information from digitizing, free-text medical records in the National Taiwan University Hospital database. PMID:25055314

  8. Accelerated Simplified Swarm Optimization with Exploitation Search Scheme for Data Clustering.

    Wei-Chang Yeh

    Full Text Available Data clustering is commonly employed in many disciplines. The aim of clustering is to partition a set of data into clusters, in which objects within the same cluster are similar and dissimilar to other objects that belong to different clusters. Over the past decade, the evolutionary algorithm has been commonly used to solve clustering problems. This study presents a novel algorithm based on simplified swarm optimization, an emerging population-based stochastic optimization approach with the advantages of simplicity, efficiency, and flexibility. This approach combines variable vibrating search (VVS and rapid centralized strategy (RCS in dealing with clustering problem. VVS is an exploitation search scheme that can refine the quality of solutions by searching the extreme points nearby the global best position. RCS is developed to accelerate the convergence rate of the algorithm by using the arithmetic average. To empirically evaluate the performance of the proposed algorithm, experiments are examined using 12 benchmark datasets, and corresponding results are compared with recent works. Results of statistical analysis indicate that the proposed algorithm is competitive in terms of the quality of solutions.

  9. Costly Search with Adverse Selection: Solicitation Curse vs. Accelerating Blessing

    Marilyn Pease; Kyungmin Kim

    2014-01-01

    We study the effects of endogenizing search intensity in sequential search models of trading under adverse selection. Ceteris paribus, the low-type seller obtains more surplus from search and, therefore, searches more intensively than the high-type seller. This has two ramifications for trade. On the one hand, a seller who successfully finds a buyer is more likely to be the low type (solicitation curse). On the other hand, since the low-type seller leaves the market even faster than the high-...

  10. Sequence heterogeneity accelerates protein search for targets on DNA

    The process of protein search for specific binding sites on DNA is fundamentally important since it marks the beginning of all major biological processes. We present a theoretical investigation that probes the role of DNA sequence symmetry, heterogeneity, and chemical composition in the protein search dynamics. Using a discrete-state stochastic approach with a first-passage events analysis, which takes into account the most relevant physical-chemical processes, a full analytical description of the search dynamics is obtained. It is found that, contrary to existing views, the protein search is generally faster on DNA with more heterogeneous sequences. In addition, the search dynamics might be affected by the chemical composition near the target site. The physical origins of these phenomena are discussed. Our results suggest that biological processes might be effectively regulated by modifying chemical composition, symmetry, and heterogeneity of a genome

  11. Sequence heterogeneity accelerates protein search for targets on DNA

    Shvets, Alexey A.; Kolomeisky, Anatoly B., E-mail: tolya@rice.edu [Department of Chemistry and Center for Theoretical Biological Physics, Rice University, Houston, Texas 77005 (United States)

    2015-12-28

    The process of protein search for specific binding sites on DNA is fundamentally important since it marks the beginning of all major biological processes. We present a theoretical investigation that probes the role of DNA sequence symmetry, heterogeneity, and chemical composition in the protein search dynamics. Using a discrete-state stochastic approach with a first-passage events analysis, which takes into account the most relevant physical-chemical processes, a full analytical description of the search dynamics is obtained. It is found that, contrary to existing views, the protein search is generally faster on DNA with more heterogeneous sequences. In addition, the search dynamics might be affected by the chemical composition near the target site. The physical origins of these phenomena are discussed. Our results suggest that biological processes might be effectively regulated by modifying chemical composition, symmetry, and heterogeneity of a genome.

  12. A search for integrable four-dimensional nonlinear accelerator lattices

    Nagaitsev, S

    2012-01-01

    Integrable nonlinear motion in accelerators has the potential to introduce a large betatron tune spread to suppress instabilities and to mitigate the effects of space charge and magnetic field errors. To create such an accelerator lattice one has to find magnetic and/or electric field combinations leading to a stable integrable motion. This paper presents families of lattices with one invariant where bounded motion can be easily created in large volumes of the phase space. In addition, it presents two examples of integrable nonlinear accelerator lattices, realizable with longitudinal-coordinate-dependent magnetic or electric fields with the stable nonlinear motion, which can be solved in terms of separable variables.

  13. On a criterion of similarity of the plasma accelerators of the stationary plasma jet engine type

    One examined operation of ATON stationary plasma jet engine with various working gases. Applying criterion of similarity one selected the optimal operation of engine using krypton. Paper presents comparison integral parameters of engine operated by krypton and xenon. It is shown that when using various working media engine operates under similar modes at similar values of similarity criterion

  14. A search for integrable four-dimensional nonlinear accelerator lattices

    Nagaitsev, S.; Danilov, V.

    2012-01-01

    Integrable nonlinear motion in accelerators has the potential to introduce a large betatron tune spread to suppress instabilities and to mitigate the effects of space charge and magnetic field errors. To create such an accelerator lattice one has to find magnetic and/or electric field combinations leading to a stable integrable motion. This paper presents families of lattices with one invariant where bounded motion can be easily created in large volumes of the phase space. In addition, it pre...

  15. GHOSTM: a GPU-accelerated homology search tool for metagenomics.

    Shuji Suzuki

    Full Text Available BACKGROUND: A large number of sensitive homology searches are required for mapping DNA sequence fragments to known protein sequences in public and private databases during metagenomic analysis. BLAST is currently used for this purpose, but its calculation speed is insufficient, especially for analyzing the large quantities of sequence data obtained from a next-generation sequencer. However, faster search tools, such as BLAT, do not have sufficient search sensitivity for metagenomic analysis. Thus, a sensitive and efficient homology search tool is in high demand for this type of analysis. METHODOLOGY/PRINCIPAL FINDINGS: We developed a new, highly efficient homology search algorithm suitable for graphics processing unit (GPU calculations that was implemented as a GPU system that we called GHOSTM. The system first searches for candidate alignment positions for a sequence from the database using pre-calculated indexes and then calculates local alignments around the candidate positions before calculating alignment scores. We implemented both of these processes on GPUs. The system achieved calculation speeds that were 130 and 407 times faster than BLAST with 1 GPU and 4 GPUs, respectively. The system also showed higher search sensitivity and had a calculation speed that was 4 and 15 times faster than BLAT with 1 GPU and 4 GPUs. CONCLUSIONS: We developed a GPU-optimized algorithm to perform sensitive sequence homology searches and implemented the system as GHOSTM. Currently, sequencing technology continues to improve, and sequencers are increasingly producing larger and larger quantities of data. This explosion of sequence data makes computational analysis with contemporary tools more difficult. We developed GHOSTM, which is a cost-efficient tool, and offer this tool as a potential solution to this problem.

  16. Accelerating dark-matter axion searches with quantum measurement technology

    Zheng, Huaixiu; Silveri, Matti; Brierley, R. T.; Girvin, S. M.; Lehnert, K. W.

    2016-01-01

    The axion particle, a consequence of an elegant hypothesis that resolves the strong-CP problem of quantum chromodynamics, is a plausible origin for cosmological dark matter. In searches for axionic dark matter that detect the conversion of axions to microwave photons, the quantum noise associated with microwave vacuum fluctuations will soon limit the rate at which parameter space is searched. Here we show that this noise can be partially overcome either by squeezing the quantum vacuum using r...

  17. Complementarity of Indirect and Accelerator Dark Matter Searches

    G. Bertone; Cerdeño, D. G.; Fornasa, M.; L. Pieri; Ruiz de Austri, R.; Trotta, R.

    2011-01-01

    Even if supersymmetric particles are found at the Large Hadron Collider (LHC), it will be difficult to prove that they constitute the bulk of the dark matter (DM) in the Universe using LHC data alone. We study the complementarity of LHC and DM indirect searches, working out explicitly the reconstruction of the DM properties for a specific benchmark model in the coannihilation region of a 24-parameters supersymmetric model. Combining mock high-luminosity LHC data with presentday null searches ...

  18. Searching the protein structure database for ligand-binding site similarities using CPASS v.2

    Caprez Adam

    2011-01-01

    Full Text Available Abstract Background A recent analysis of protein sequences deposited in the NCBI RefSeq database indicates that ~8.5 million protein sequences are encoded in prokaryotic and eukaryotic genomes, where ~30% are explicitly annotated as "hypothetical" or "uncharacterized" protein. Our Comparison of Protein Active-Site Structures (CPASS v.2 database and software compares the sequence and structural characteristics of experimentally determined ligand binding sites to infer a functional relationship in the absence of global sequence or structure similarity. CPASS is an important component of our Functional Annotation Screening Technology by NMR (FAST-NMR protocol and has been successfully applied to aid the annotation of a number of proteins of unknown function. Findings We report a major upgrade to our CPASS software and database that significantly improves its broad utility. CPASS v.2 is designed with a layered architecture to increase flexibility and portability that also enables job distribution over the Open Science Grid (OSG to increase speed. Similarly, the CPASS interface was enhanced to provide more user flexibility in submitting a CPASS query. CPASS v.2 now allows for both automatic and manual definition of ligand-binding sites and permits pair-wise, one versus all, one versus list, or list versus list comparisons. Solvent accessible surface area, ligand root-mean square difference, and Cβ distances have been incorporated into the CPASS similarity function to improve the quality of the results. The CPASS database has also been updated. Conclusions CPASS v.2 is more than an order of magnitude faster than the original implementation, and allows for multiple simultaneous job submissions. Similarly, the CPASS database of ligand-defined binding sites has increased in size by ~ 38%, dramatically increasing the likelihood of a positive search result. The modification to the CPASS similarity function is effective in reducing CPASS similarity scores

  19. Gene network homology in prokaryotes using a similarity search approach: queries of quorum sensing signal transduction.

    David N Quan

    Full Text Available Bacterial cell-cell communication is mediated by small signaling molecules known as autoinducers. Importantly, autoinducer-2 (AI-2 is synthesized via the enzyme LuxS in over 80 species, some of which mediate their pathogenicity by recognizing and transducing this signal in a cell density dependent manner. AI-2 mediated phenotypes are not well understood however, as the means for signal transduction appears varied among species, while AI-2 synthesis processes appear conserved. Approaches to reveal the recognition pathways of AI-2 will shed light on pathogenicity as we believe recognition of the signal is likely as important, if not more, than the signal synthesis. LMNAST (Local Modular Network Alignment Similarity Tool uses a local similarity search heuristic to study gene order, generating homology hits for the genomic arrangement of a query gene sequence. We develop and apply this tool for the E. coli lac and LuxS regulated (Lsr systems. Lsr is of great interest as it mediates AI-2 uptake and processing. Both test searches generated results that were subsequently analyzed through a number of different lenses, each with its own level of granularity, from a binary phylogenetic representation down to trackback plots that preserve genomic organizational information. Through a survey of these results, we demonstrate the identification of orthologs, paralogs, hitchhiking genes, gene loss, gene rearrangement within an operon context, and also horizontal gene transfer (HGT. We found a variety of operon structures that are consistent with our hypothesis that the signal can be perceived and transduced by homologous protein complexes, while their regulation may be key to defining subsequent phenotypic behavior.

  20. Accelerating dark-matter axion searches with quantum measurement technology

    Zheng, Huaixiu; Brierley, R T; Girvin, S M; Lehnert, K W

    2016-01-01

    The axion particle, a consequence of an elegant hypothesis that resolves the strong-CP problem of quantum chromodynamics, is a plausible origin for cosmological dark matter. In searches for axionic dark matter that detect the conversion of axions to microwave photons, the quantum noise associated with microwave vacuum fluctuations will soon limit the rate at which parameter space is searched. Here we show that this noise can be partially overcome either by squeezing the quantum vacuum using recently developed Josephson parametric devices, or by using superconducting qubits to count microwave photons.

  1. Efficient Retrieval of Images for Search Engine by Visual Similarity and Re Ranking

    Viswa S S

    2013-01-01

    Nowadays, web scale image search engines (e.g. Google Image Search, Microsoft Live Image Search) rely almost purely on surrounding text features. Users type keywords in hope of finding a certain type of images. The search engine returns thousands of images ranked by the text keywords extracted from the surrounding text. However, many of returned images are noisy, disorganized, or irrelevant. Even Google and Microsoft have no Visual Information for searching of images. Using visual information...

  2. PHOG-BLAST – a new generation tool for fast similarity search of protein families

    Mironov Andrey A

    2006-06-01

    Full Text Available Abstract Background The need to compare protein profiles frequently arises in various protein research areas: comparison of protein families, domain searches, resolution of orthology and paralogy. The existing fast algorithms can only compare a protein sequence with a protein sequence and a profile with a sequence. Algorithms to compare profiles use dynamic programming and complex scoring functions. Results We developed a new algorithm called PHOG-BLAST for fast similarity search of profiles. This algorithm uses profile discretization to convert a profile to a finite alphabet and utilizes hashing for fast search. To determine the optimal alphabet, we analyzed columns in reliable multiple alignments and obtained column clusters in the 20-dimensional profile space by applying a special clustering procedure. We show that the clustering procedure works best if its parameters are chosen so that 20 profile clusters are obtained which can be interpreted as ancestral amino acid residues. With these clusters, only less than 2% of columns in multiple alignments are out of clusters. We tested the performance of PHOG-BLAST vs. PSI-BLAST on three well-known databases of multiple alignments: COG, PFAM and BALIBASE. On the COG database both algorithms showed the same performance, on PFAM and BALIBASE PHOG-BLAST was much superior to PSI-BLAST. PHOG-BLAST required 10–20 times less computer memory and computation time than PSI-BLAST. Conclusion Since PHOG-BLAST can compare multiple alignments of protein families, it can be used in different areas of comparative proteomics and protein evolution. For example, PHOG-BLAST helped to build the PHOG database of phylogenetic orthologous groups. An essential step in building this database was comparing protein complements of different species and orthologous groups of different taxons on a personal computer in reasonable time. When it is applied to detect weak similarity between protein families, PHOG-BLAST is less

  3. Breast cancer stories on the internet: improving search facilities to help patients find stories of similar others

    Overberg, Regina Ingrid

    2013-01-01

    The primary aim of this thesis is to gain insight into which search facilities for spontaneously published stories facilitate breast cancer patients in finding stories by other patients in a similar situation. According to the narrative approach, social comparison theory, and social cognitive theory, reading stories about similar others may have the most positive impact. The research followed a user-centred design: users of search facilities (i.e., patients who want to read stories written by...

  4. Identification of protein biochemical functions by similarity search using the molecular surface database eF-site

    Kinoshita, Kengo; Nakamura, Haruki

    2003-01-01

    The identification of protein biochemical functions based on their three-dimensional structures is strongly required in the post-genome-sequencing era. We have developed a new method to identify and predict protein biochemical functions using the similarity information of molecular surface geometries and electrostatic potentials on the surfaces. Our prediction system consists of a similarity search method based on a clique search algorithm and the molecular surface database eF-site (electrost...

  5. PSimScan: algorithm and utility for fast protein similarity search.

    Anna Kaznadzey

    Full Text Available In the era of metagenomics and diagnostics sequencing, the importance of protein comparison methods of boosted performance cannot be overstated. Here we present PSimScan (Protein Similarity Scanner, a flexible open source protein similarity search tool which provides a significant gain in speed compared to BLASTP at the price of controlled sensitivity loss. The PSimScan algorithm introduces a number of novel performance optimization methods that can be further used by the community to improve the speed and lower hardware requirements of bioinformatics software. The optimization starts at the lookup table construction, then the initial lookup table-based hits are passed through a pipeline of filtering and aggregation routines of increasing computational complexity. The first step in this pipeline is a novel algorithm that builds and selects 'similarity zones' aggregated from neighboring matches on small arrays of adjacent diagonals. PSimScan performs 5 to 100 times faster than the standard NCBI BLASTP, depending on chosen parameters, and runs on commodity hardware. Its sensitivity and selectivity at the slowest settings are comparable to the NCBI BLASTP's and decrease with the increase of speed, yet stay at the levels reasonable for many tasks. PSimScan is most advantageous when used on large collections of query sequences. Comparing the entire proteome of Streptocuccus pneumoniae (2,042 proteins to the NCBI's non-redundant protein database of 16,971,855 records takes 6.5 hours on a moderately powerful PC, while the same task with the NCBI BLASTP takes over 66 hours. We describe innovations in the PSimScan algorithm in considerable detail to encourage bioinformaticians to improve on the tool and to use the innovations in their own software development.

  6. The Cost of Search for Multiple Targets: Effects of Practice and Target Similarity

    Menneer, Tamaryn; Cave, Kyle R.; Donnelly, Nick

    2009-01-01

    With the use of X-ray images, performance in the simultaneous search for two target categories was compared with performance in two independent searches, one for each category. In all cases, displays contained one target at most. Dual-target search, for both categories simultaneously, produced a cost in accuracy, although the magnitude of this…

  7. Application of Group Theory of the Similarity Solutions of the Power law Fluids Flow Past a Suddenly Accelerating Plate

    Krishna Lal

    1970-01-01

    Full Text Available The motion of a power law fluid past a suddenly accelerated wall which moves with a constant velocity U (t parallel to the wall has been considered for the similarity analysis. Recently this problem has been discussed and two possible group of transformation have been used by T.Y. Na/sup 1/. In this paper the third possible transformation has been found. The variation of the wall velocity U (t with time, t, has been worked out.

  8. Acceleration of stable interface structure searching using a kriging approach

    Kiyohara, Shin; Oda, Hiromi; Tsuda, Koji; Mizoguchi, Teruyasu

    2016-04-01

    Crystalline interfaces have a tremendous impact on the properties of materials. Determination of the atomic structure of the interface is crucial for a comprehensive understanding of the interface properties. Despite this importance, extensive calculation is necessary to determine even one interface structure. In this study, we apply a technique called kriging, borrowed from geostatistics, to accelerate the determination of the interface structure. The atomic structure of simplified coincidence-site lattice interfaces were determined using the kriging approach. Our approach successfully determined the most stable interface structure with an efficiency almost 2 orders of magnitude better than the traditional “brute force” approach.

  9. Early Visual Tagging: Effects of Target-Distractor Similarity and Old Age on Search, Subitization, and Counting

    Watson, Derrick G.; Maylor, Elizabeth A.; Allen, Gareth E. J.; Bruce, Lucy A. M.

    2007-01-01

    Three experiments examined the effects of target-distractor (T-D) similarity and old age on the efficiency of searching for single targets and enumerating multiple targets. Experiment 1 showed that increasing T-D similarity selectively reduced the efficiency of enumerating small (less than 4) numerosities (subitizing) but had little effect on…

  10. Application of 3D Zernike descriptors to shape-based ligand similarity searching

    Venkatraman Vishwesh

    2009-12-01

    Full Text Available Abstract Background The identification of promising drug leads from a large database of compounds is an important step in the preliminary stages of drug design. Although shape is known to play a key role in the molecular recognition process, its application to virtual screening poses significant hurdles both in terms of the encoding scheme and speed. Results In this study, we have examined the efficacy of the alignment independent three-dimensional Zernike descriptor (3DZD for fast shape based similarity searching. Performance of this approach was compared with several other methods including the statistical moments based ultrafast shape recognition scheme (USR and SIMCOMP, a graph matching algorithm that compares atom environments. Three benchmark datasets are used to thoroughly test the methods in terms of their ability for molecular classification, retrieval rate, and performance under the situation that simulates actual virtual screening tasks over a large pharmaceutical database. The 3DZD performed better than or comparable to the other methods examined, depending on the datasets and evaluation metrics used. Reasons for the success and the failure of the shape based methods for specific cases are investigated. Based on the results for the three datasets, general conclusions are drawn with regard to their efficiency and applicability. Conclusion The 3DZD has unique ability for fast comparison of three-dimensional shape of compounds. Examples analyzed illustrate the advantages and the room for improvements for the 3DZD.

  11. Development of methods for beam angle optimization for IMRT using an accelerated exhaustive search strategy

    Purpose: The purpose of this article is to explore the use of the accelerated exhaustive search strategy for developing and validating methods for optimizing beam orientations for intensity-modulated radiation therapy (IMRT). Combining beam-angle optimization (BAO) with intensity distribution optimization is expected to improve the quality of IMRT treatment plans. However, BAO is one of the most difficult problems to solve adequately because of the huge hyperspace of possible beam configurations (e.g., selecting 7 of 36 uniformly spaced coplanar beams would require the intercomparison of 8,347,680 IMRT plans). Methods and materials: An 'influence vector' (IV) approximation technique for high-speed estimation of IMRT dose distributions was used in combination with a fast gradient search algorithm (Newton's method) for IMRT optimization. In the IV approximation, it is assumed that the change in intensity of a ray (or bixel) proportionately changes dose along the ray. Evidence is presented that the IV approximation is valid for BAO. The scatter contribution at points away from the ray is accounted for fully in IMRT optimization after the optimum beam orientation has been determined. IVs for all candidate beam angles are generated before the start of optimization. For all subsets of beams selected from a given pool of beams (e.g., 5 of 24 uniformly spaced beams), the distribution of planning scores for the best and the worst plans, optimum angle distributions, dose distributions, and dose-volume histograms (DVH) were analyzed for one prostate and two lung cancer cases. The results of the exhaustive search technique were used to develop a 'multiresolution' search strategy. In this approach, a smaller number of beams (e.g., three) is first used to explore the hyperspace of solutions to determine the most preferred and the least preferred directions. The results of such exploration are then used as a starting point for determining an optimum configuration comprising a

  12. Search for Galactic cosmic ray accelerators with the combined IceCube+AMANDA detector

    The IceCube neutrino observatory instruments a volume of 1 cubic km of the Antarctic ice with 5160 photomultiplier tubes (PMTs) aligned on 86 strings with the goal to detect astrophysical sources of high energy neutrinos. During the construction phase from 2004 until 2011, the detector has been growing each year and data was collected in each configuration. In the season 2008/2009, 40 strings of IceCube were operated. In addition, the predecessor of IceCube, AMANDA, acted as an integrated part of the detector. With its denser spacing of PMTs, AMANDA improved the effective area below 10 TeV and acted as a first generation low energy extension of IceCube. We present a search for astrophysical sources of neutrinos in the Milky Way with the combined detector consisting of 40 strings of IceCube plus AMANDA. Potential Galactic cosmic ray accelerators are characterized by their proximity in comparison to other objects such as AGN but their energy spectra show exponential cut-offs. In transparent sources, high energy neutrinos will follow similar soft or cut-off spectra. This strongly motivates a low energy optimized analysis with IceCube. Several test including a scan of the Galactic Plane and a dedicated analysis for the Cygnus region are presented. No neutrino signal has been observed and upper limits are reported.

  13. Massively Multi-core Acceleration of a Document-Similarity Classifier to Detect Web Attacks

    Ulmer, C; Gokhale, M; Top, P; Gallagher, B; Eliassi-Rad, T

    2010-01-14

    This paper describes our approach to adapting a text document similarity classifier based on the Term Frequency Inverse Document Frequency (TFIDF) metric to two massively multi-core hardware platforms. The TFIDF classifier is used to detect web attacks in HTTP data. In our parallel hardware approaches, we design streaming, real time classifiers by simplifying the sequential algorithm and manipulating the classifier's model to allow decision information to be represented compactly. Parallel implementations on the Tilera 64-core System on Chip and the Xilinx Virtex 5-LX FPGA are presented. For the Tilera, we employ a reduced state machine to recognize dictionary terms without requiring explicit tokenization, and achieve throughput of 37MB/s at slightly reduced accuracy. For the FPGA, we have developed a set of software tools to help automate the process of converting training data to synthesizable hardware and to provide a means of trading off between accuracy and resource utilization. The Xilinx Virtex 5-LX implementation requires 0.2% of the memory used by the original algorithm. At 166MB/s (80X the software) the hardware implementation is able to achieve Gigabit network throughput at the same accuracy as the original algorithm.

  14. Efficient Retrieval of Images for Search Engine by Visual Similarity and Re Ranking

    Viswa S S

    2013-06-01

    Full Text Available Nowadays, web scale image search engines (e.g.Google Image Search, Microsoft Live ImageSearch rely almost purely on surrounding textfeatures. Users type keywords in hope of finding acertain type of images. The search engine returnsthousands of images ranked by the text keywordsextracted from the surrounding text. However,many of returned images are noisy, disorganized, orirrelevant. Even Google and Microsoft have noVisual Information for searching of images. Usingvisual information to re rank and improve textbased image search results is the idea. Thisimproves the precision of the text based imagesearch ranking by incorporating the informationconveyed by the visual modality.The typicalassumption that the top-images in the text-basedsearch result are equally relevant is relaxed bylinking the relevance of the images to their initialrank positions. Then, a number of images from theinitial search result are employed as the prototypesthat serve to visually represent the query and thatare subsequently used to construct meta re rankers.i.e. The most relevant images are found by visualsimilarity and the average scores are calculated. Byapplying different meta re rankers to an image fromthe initial result, re ranking scores are generated,which are then used to find the new rank positionfor an image in the re ranked search result.Humansupervision is introduced to learn the model weightsoffline, prior to the online re ranking process. Whilemodel learning requires manual labelling of theresults for a few queries, the resulting model isquery independent and therefore applicable to anyother query. The experimental results on arepresentative web image search dataset comprising353 queries demonstrate that the proposed methodoutperforms the existing supervised andunsupervised Re ranking approaches. Moreover, itimproves the performance over the text-based imagesearch engine by morethan 25.48%

  15. RAPSearch2: a fast and memory-efficient protein similarity search tool for next-generation sequencing data

    Zhao, Yongan; Tang, Haixu; Ye, Yuzhen

    2011-01-01

    Summary: With the wide application of next-generation sequencing (NGS) techniques, fast tools for protein similarity search that scale well to large query datasets and large databases are highly desirable. In a previous work, we developed RAPSearch, an algorithm that achieved a ~20–90-fold speedup relative to BLAST while still achieving similar levels of sensitivity for short protein fragments derived from NGS data. RAPSearch, however, requires a substantial memory footprint to identify align...

  16. Breast cancer stories on the internet : improving search facilities to help patients find stories of similar others

    Overberg, Regina Ingrid

    2013-01-01

    The primary aim of this thesis is to gain insight into which search facilities for spontaneously published stories facilitate breast cancer patients in finding stories by other patients in a similar situation. According to the narrative approach, social comparison theory, and social cognitive theory

  17. Search for doubly-charged negative ions via accelerator mass spectrometry

    The Argonne FN tandem accelerator in conjunction with an Enge split-pole magnetic spectrograph has been used as a highly sensitive mass spectrometer to search for doubly charged negative ions of 11B, 12C and 16O. No evidence for the formation of these ions in an inverted sputter source and the subsequent acceleration in the tandem has been found. The following limits for the ratio of doubly-charged to singly-charged ions were measured: X--/X- -15, 11B; -15, 12C; -14, 16O. A relatively abundant formation of the short lived, metastable He- ion in the sputter source has been observed

  18. BlastMultAl, a Blast Extension for Similarity Searching with Alignment Graphs

    Nicodème, Pierre

    1996-01-01

    We describe a new method of processing similarity queries of a proteic multiple alignment with a set (database) of protein sequences, or similarity queries of a protein sequence with a set of protein alignments. We use a representation of multiple alignments as alignment-graphs. Comparisons with different classical methods is made. This new method allows the detection of subtle similarities which are not found by the other methods. It has direct applications for similarities querying with the...

  19. SHOP: receptor-based scaffold hopping by GRID-based similarity searches

    Bergmann, Rikke; Liljefors, Tommy; Sørensen, Morten D;

    2009-01-01

    find known active CDK2 scaffolds in a database. Additionally, SHOP was used for suggesting new inhibitors of p38 MAP kinase. Four p38 complexes were used to perform six scaffold searches. Several new scaffolds were suggested, and the resulting compounds were successfully docked into the query proteins....

  20. Finding and Reusing Learning Materials with Multimedia Similarity Search and Social Networks

    Little, Suzanne; Ferguson, Rebecca; Ruger, Stefan

    2012-01-01

    The authors describe how content-based multimedia search technologies can be used to help learners find new materials and learning pathways by identifying semantic relationships between educational resources in a social learning network. This helps users--both learners and educators--to explore and find material to support their learning aims.…

  1. Acceleration Method of Neighbor Search with GRAPE and Morton-ordering

    Saitoh, T. R.; J. Koda

    2003-01-01

    We describe a new method to accelerate neighbor searches on GRAPE, i.e. a special purpose hardware that efficiently calculates gravitational forces and potentials in $N$-body simulations. In addition to the gravitational calculations, GRAPE simultaneously constructs the lists of neighbor particles that are necessary for Smoothed Particle Hydrodynamics (SPH). However, data transfer of the neighbor lists from GRAPE to the host computer is time consuming, and can be a bottleneck. In fact, the da...

  2. Improving GPU-accelerated Adaptive IDW Interpolation Algorithm Using Fast kNN Search

    Mei, Gang; Xu, Nengxiong; Xu, Liangliang

    2016-01-01

    This paper presents an efficient parallel Adaptive Inverse Distance Weighting (AIDW) interpolation algorithm on modern Graphics Processing Unit (GPU). The presented algorithm is an improvement of our previous GPU-accelerated AIDW algorithm by adopting fast k-Nearest Neighbors (kNN) search. In AIDW, it needs to find several nearest neighboring data points for each interpolated point to adaptively determine the power parameter; and then the desired prediction value of the interpolated point is ...

  3. FSim: A Novel Functional Similarity Search Algorithm and Tool for Discovering Functionally Related Gene Products

    2014-01-01

    Background. During the analysis of genomics data, it is often required to quantify the functional similarity of genes and their products based on the annotation information from gene ontology (GO) with hierarchical structure. A flexible and user-friendly way to estimate the functional similarity of genes utilizing GO annotation is therefore highly desired. Results. We proposed a novel algorithm using a level coefficient-weighted model to measure the functional similarity of gene products base...

  4. Efficient EMD-based Similarity Search in Multimedia Databases via Flexible Dimensionality Reduction

    Wichterich, Marc; Assent, Ira; Philipp, Kranen;

    2008-01-01

    The Earth Mover's Distance (EMD) was developed in computer vision as a flexible similarity model that utilizes similarities in feature space to define a high quality similarity measure in feature representation space. It has been successfully adopted in a multitude of applications with low to...... dimensionality reduction techniques for the EMD in a filter-and-refine architecture for efficient lossless retrieval. Thorough experimental evaluation on real world data sets demonstrates a substantial reduction of the number of expensive high-dimensional EMD computations and thus remarkably faster response...

  5. A Commodity Information Search Model of E-Commerce Search Engine Based on Semantic Similarity and Multi-Attribute Decision Method

    Ziming Zeng

    2010-01-01

    The paper presented an intelligent commodity information search model, which integrates semantic retrieval andmulti-attribute decision method. First, semantic similarity is computed by constructing semantic vector-space, inorder to realize the semantic consistency between retrieved result and customer’s query. Besides, TOPSISmethod is also utilized to construct the comparison mechanism of commodity by calculating the utility value ofeach retrieved commodity. Finally, the experiment is conduct...

  6. Proposal for a Similar Question Search System on a Q&A Site

    Katsutoshi Kanamori

    2014-06-01

    Full Text Available There is a service to help Internet users obtain answers to specific questions when they visit a Q&A site. A Q&A site is very useful for the Internet user, but posted questions are often not answered immediately. This delay in answering occurs because in most cases another site user is answering the question manually. In this study, we propose a system that can present a question that is similar to a question posted by a user. An advantage of this system is that a user can refer to an answer to a similar question. This research measures the similarity of a candidate question based on word and dependency parsing. In an experiment, we examined the effectiveness of the proposed system for questions actually posted on the Q&A site. The result indicates that the system can show the questioner the answer to a similar question. However, the system still has a number of aspects that should be improved.

  7. Managing Biomedical Image Metadata for Search and Retrieval of Similar Images

    Korenblum, Daniel; Rubin, Daniel; Napel, Sandy; Cesar RODRIGUEZ; Beaulieu, Chris

    2010-01-01

    Radiology images are generally disconnected from the metadata describing their contents, such as imaging observations (“semantic” metadata), which are usually described in text reports that are not directly linked to the images. We developed a system, the Biomedical Image Metadata Manager (BIMM) to (1) address the problem of managing biomedical image metadata and (2) facilitate the retrieval of similar images using semantic feature metadata. Our approach allows radiologists, researchers, and ...

  8. Application of kernel functions for accurate similarity search in large chemical databases

    2010-01-01

    Background Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screening among others. It is widely believed that structure based methods provide an efficient way to do the query. Recently various graph kernel functions have been designed to capture the intrinsic similarity of graphs. Though successful in constructing accurate predictive and classification models, graph kernel functions...

  9. Integrating structure- and ligand-based virtual screening: comparison of individual, parallel, and fused molecular docking and similarity search calculations on multiple targets.

    Tan, Lu; Geppert, Hanna; Sisay, Mihiret T; Gütschow, Michael; Bajorath, Jürgen

    2008-10-01

    Similarity searching is often used to preselect compounds for docking, thereby decreasing the size of screening databases. However, integrated structure- and ligand-based screening schemes are rare at present. Docking and similarity search calculations using 2D fingerprints were carried out in a comparative manner on nine target enzymes, for which significant numbers of diverse inhibitors could be obtained. In the absence of knowledge-based docking constraints and target-directed parameter optimisation, fingerprint searching displayed a clear preference over docking calculations. Alternative combinations of docking and similarity search results were investigated and found to further increase compound recall of individual methods in a number of instances. When the results of similarity searching and docking were combined, parallel selection of candidate compounds from individual rankings was generally superior to rank fusion. We suggest that complementary results from docking and similarity searching can be captured by integrated compound selection schemes. PMID:18651695

  10. HBLAST: Parallelised sequence similarity--A Hadoop MapReducable basic local alignment search tool.

    O'Driscoll, Aisling; Belogrudov, Vladislav; Carroll, John; Kropp, Kai; Walsh, Paul; Ghazal, Peter; Sleator, Roy D

    2015-04-01

    The recent exponential growth of genomic databases has resulted in the common task of sequence alignment becoming one of the major bottlenecks in the field of computational biology. It is typical for these large datasets and complex computations to require cost prohibitive High Performance Computing (HPC) to function. As such, parallelised solutions have been proposed but many exhibit scalability limitations and are incapable of effectively processing "Big Data" - the name attributed to datasets that are extremely large, complex and require rapid processing. The Hadoop framework, comprised of distributed storage and a parallelised programming framework known as MapReduce, is specifically designed to work with such datasets but it is not trivial to efficiently redesign and implement bioinformatics algorithms according to this paradigm. The parallelisation strategy of "divide and conquer" for alignment algorithms can be applied to both data sets and input query sequences. However, scalability is still an issue due to memory constraints or large databases, with very large database segmentation leading to additional performance decline. Herein, we present Hadoop Blast (HBlast), a parallelised BLAST algorithm that proposes a flexible method to partition both databases and input query sequences using "virtual partitioning". HBlast presents improved scalability over existing solutions and well balanced computational work load while keeping database segmentation and recompilation to a minimum. Enhanced BLAST search performance on cheap memory constrained hardware has significant implications for in field clinical diagnostic testing; enabling faster and more accurate identification of pathogenic DNA in human blood or tissue samples. PMID:25625550

  11. Search for doubly-charged negative ions via accelerator mass spectrometry

    Kutschera, W.; Frekers, D.; Pardo, R.; Rehm, K.E.; Smither, R.K.; Yntema, J.L.

    1983-01-01

    The Argonne FN tandem accelerator in conjunction with an Enge split-pole magnetic spectrograph has been used as a highly sensitive mass spectrometer to search for doubly charged negative ions of /sup 11/B, /sup 12/C and /sup 16/O. No evidence for the formation of these ions in an inverted sputter source and the subsequent acceleration in the tandem has been found. The following limits for the ratio of doubly-charged to singly-charged ions were measured: X/sup - -//X/sup -/ < 1 x 10/sup -15/, /sup 11/B; < 2 x 10/sup -15/, /sup 12/C; < 2 x 10/sup -14/, /sup 16/O. A relatively abundant formation of the short lived, metastable He/sup -/ ion in the sputter source has been observed.

  12. Efficient SAT engines for concise logics: Accelerating proof search for zero-one linear constraint systems

    Fränzle, Martin; Herde, Christian

    We investigate the problem of generalizing acceleration techniques as found in recent satisfiability engines for conjunctive normal forms (CNFs) to linear constraint systems over the Booleans. The rationale behind this research is that rewriting the propositional formulae occurring in e.g. bounded...... model checking (BMC) [Biere, Cimatti,Zhu, 1999] to CNF requires a blowup in either the formula size (worst-case exponential) or in the number of propositional variables (linear, thus yielding a worst-case exponential blow-up of the search space). We demonstrate that acceleration techniques like....... Despite the more expressive input language, the performance of our prototype implementation comes surprisingly close to that of state-of-the-art CNF-SAT engines like ZChaff [Moskewicz e.a., 2001]. First experiments with bounded model-construction problems show that the overhead in the satisfiability...

  13. Searching for magnetic monopoles trapped in accelerator material at the Large Hadron Collider

    Joergensen, M Dam; Hächler, H -P; Hirt, A; Katre, A; Mermod, P; Milstead, D; Sloan, T

    2012-01-01

    If produced in high energy particle collisions at the LHC, magnetic monopoles could stop in material surrounding the interaction points. Obsolete parts of the beam pipe near the CMS interaction region, which were exposed to the products of pp and heavy ion collisions, were analysed using a SQUID-based magnetometer. The purpose of this work is to quantify the performance of the magnetometer in the context of a monopole search using a small set of samples of accelerator material ahead of the 2013 shutdown.

  14. Searching for magnetic monopoles trapped in accelerator material at the Large Hadron Collider

    Joergensen, M. Dam; De Roeck, A; Hächler, H. -P.; Hirt, A.; Katre, A.; Mermod, P.; D. Milstead; Sloan, T.

    2012-01-01

    If produced in high energy particle collisions at the LHC, magnetic monopoles could stop in material surrounding the interaction points. Obsolete parts of the beam pipe near the CMS interaction region, which were exposed to the products of pp and heavy ion collisions, were analysed using a SQUID-based magnetometer. The purpose of this work is to quantify the performance of the magnetometer in the context of a monopole search using a small set of samples of accelerator material ahead of the 20...

  15. Web Similarity

    Cohen, Andrew; Vitányi, Paul

    2015-01-01

    Normalized web distance (NWD) is a similarity or normalized semantic distance based on the World Wide Web or any other large electronic database, for instance Wikipedia, and a search engine that returns reliable aggregate page counts. For sets of search terms the NWD gives a similarity on a scale from 0 (identical) to 1 (completely different). The NWD approximates the similarity according to all (upper semi)computable properties. We develop the theory and give applications. The derivation of ...

  16. Geometry navigation acceleration based on automatic neighbor search and oriented bounding box in Monte Carlo simulation

    Geometry navigation plays the most fundamental role in Monte Carlo particle transport simulation. It's mainly responsible for locating a particle inside which geometry volume it is and computing the distance to the volume boundary along the certain particle trajectory during each particle history. Geometry navigation directly affects the run-time performance of the Monte Carlo particle transport simulation, especially for large scale complicated systems. Two geometry acceleration algorithms, the automatic neighbor search algorithm and the oriented bounding box algorithm, are presented for improving geometry navigation performance. The algorithms have been implemented in the Super Monte Carlo Calculation Program for Nuclear and Radiation Process (SuperMC) version 2.0. The FDS-II and ITER benchmark models have been tested to highlight the efficiency gains that can be achieved by using the acceleration algorithms. The exact gains may be problem dependent, but testing results showed that runtime of Monte Carlo simulation can be considerably reduced 50%∼60% with the proposed acceleration algorithms. (author)

  17. SimSearch : a new variant of dynamic programming based on distance series for optimal and near-optimal similarity discovery in biological sequences

    Sérgio DEUSDADO; Carvalho, Paulo

    2009-01-01

    In this paper, we propose SimSearch, an algorithm implementing a new variant of dynamic programming based on distance series for optimal and near-optimal similarity discovery in biological sequences. The initial phase of SimSearch is devoted to fulfil the binary similarity matrices by signalling the distances between occurrences of the same symbol. The scoring scheme is further applied, when analysed the maximal extension of the pattern. Employing bit parallelism to analyse the global similar...

  18. Accelerator

    The invention claims equipment for stabilizing the position of the front covers of the accelerator chamber in cyclic accelerators which significantly increases accelerator reliability. For stabilizing, it uses hydraulic cushions placed between the electromagnet pole pieces and the front chamber covers. The top and the bottom cushions are hydraulically connected. The cushions are disconnected and removed from the hydraulic line using valves. (J.P.)

  19. Improving performance of content-based image retrieval schemes in searching for similar breast mass regions: an assessment

    This study aims to assess three methods commonly used in content-based image retrieval (CBIR) schemes and investigate the approaches to improve scheme performance. A reference database involving 3000 regions of interest (ROIs) was established. Among them, 400 ROIs were randomly selected to form a testing dataset. Three methods, namely mutual information, Pearson's correlation and a multi-feature-based k-nearest neighbor (KNN) algorithm, were applied to search for the 15 'the most similar' reference ROIs to each testing ROI. The clinical relevance and visual similarity of searching results were evaluated using the areas under receiver operating characteristic (ROC) curves (AZ) and average mean square difference (MSD) of the mass boundary spiculation level ratings between testing and selected ROIs, respectively. The results showed that the AZ values were 0.893 ± 0.009, 0.606 ± 0.021 and 0.699 ± 0.026 for the use of KNN, mutual information and Pearson's correlation, respectively. The AZ values increased to 0.724 ± 0.017 and 0.787 ± 0.016 for mutual information and Pearson's correlation when using ROIs with the size adaptively adjusted based on actual mass size. The corresponding MSD values were 2.107 ± 0.718, 2.301 ± 0.733 and 2.298 ± 0.743. The study demonstrates that due to the diversity of medical images, CBIR schemes using multiple image features and mass size-based ROIs can achieve significantly improved performance.

  20. Accelerating and separating mixed beams of ions with similar charge to mass ratio in the CERN ps complex

    This paper reports that sulphur 32 ions were accelerated by the CERN machines to a world record energy of 6.4 TeV. An Electron Cyclotron Resonance source produces sulphur ions as a 5 per cent contamination of an oxygen ion beam. As their charge-to-mass ratios differ by only 5.4 E-4, the two species are not distinguishable by the downstream accelerators (RFQ, Linac 1, PSB), though measurable in a specially equipped spectrometer line. In this way, enough current is available for controlled acceleration at low beta in the PSB. However, at phase transition energy in the PS - about 6 GeV/nucleon (GeV/u) - this synchrotron becomes an extremely fine spectrometer, with sulphur 16+ ions being driven inwards, and oxygen 8+ outwards. This can be used for separating the beams by manipulating the low-level radio-frequency system at transition, so that either oxygen or sulphur is selected. Indeed, the SPS could be fed with a fairly intense oxygen beam for setting-up, and later with some 2E7 sulphur ions per PS cycle. The required RF manipulations, the present understanding on beam dynamics at transition, as well as diagnostic techniques for determining the amount of sulphur are presented

  1. Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams.

    Raschke, S; Spickermann, S; Toncian, T; Swantusch, M; Boeker, J; Giesen, U; Iliakis, G; Willi, O; Boege, F

    2016-01-01

    Ultra-short proton pulses originating from laser-plasma accelerators can provide instantaneous dose rates at least 10(7)-fold in excess of conventional, continuous proton beams. The impact of such extremely high proton dose rates on A549 human lung cancer cells was compared with conventionally accelerated protons and 90 keV X-rays. Between 0.2 and 2 Gy, the yield of DNA double strand breaks (foci of phosphorylated histone H2AX) was not significantly different between the two proton sources or proton irradiation and X-rays. Protein nitroxidation after 1 h judged by 3-nitrotyrosine generation was 2.5 and 5-fold higher in response to conventionally accelerated protons compared to laser-driven protons and X-rays, respectively. This difference was significant (p < 0.01) between 0.25 and 1 Gy. In conclusion, ultra-short proton pulses originating from laser-plasma accelerators have a similar DNA damaging potential as conventional proton beams, while inducing less immediate nitroxidative stress, which probably entails a distinct therapeutic potential. PMID:27578260

  2. Similar muscles contribute to horizontal and vertical acceleration of center of mass in forward and backward walking: implications for neural control.

    Jansen, Karen; De Groote, Friedl; Massaad, Firas; Meyns, Pieter; Duysens, Jacques; Jonkers, Ilse

    2012-06-01

    Leg kinematics during backward walking (BW) are very similar to the time-reversed kinematics during forward walking (FW). This suggests that the underlying muscle activation pattern could originate from a simple time reversal, as well. Experimental electromyography studies have confirmed that this is the case for some muscles. Furthermore, it has been hypothesized that muscles showing a time reversal should also exhibit a reversal in function [from accelerating the body center of mass (COM) to decelerating]. However, this has not yet been verified in simulation studies. In the present study, forward simulations were used to study the effects of muscles on the acceleration of COM in FW and BW. We found that a reversal in function was indeed present in the muscle control of the horizontal movement of COM (e.g., tibialis anterior and gastrocnemius). In contrast, muscles' antigravity contributions maintained their function for both directions of movement. An important outcome of the present study is therefore that similar muscles can be used to achieve opposite functional demands at the level of control of the COM when walking direction is reversed. However, some muscles showed direction-specific contributions (i.e., dorsiflexors). We concluded that the changes in muscle contributions imply that a simple time reversal would be insufficient to produce BW from FW. We therefore propose that BW utilizes extra elements, presumably supraspinal, in addition to a common spinal drive. These additions are needed for propulsion and require a partial reconfiguration of lower level common networks. PMID:22423005

  3. Developing Molecular Interaction Database and Searching for Similar Pathways (MOLECULAR BIOLOGY AND INFORMATION-Biological Information Science)

    Kawashima, Shuichi; Katayama, Toshiaki; Kanehisa, Minoru

    1998-01-01

    We have developed a database named BRITE, which contains knowledge of interacting molecules and/or genes concering cell cycle and early development. Here, we report an overview of the database and the method of automatic search for functionally common sub-pathways between two biological pathways in BRITE.

  4. Topology-based document similarity search algorithm%一种基于文档拓扑的相似性搜索算法

    杨艳; 朱戈; 范文彬

    2011-01-01

    Searching for similar documents from the large number of documents quickly and efficiently is an important and time-consuming problem.The existing algorithms first find the candidate document set, and then sort them based on a document related evaluation to identify the most relevant ones.A topology-based document similarity search algorithm--Hub-Nis put forward, and the document similarity search problem is transformed into graph search problem, applying the pruning techniques, reducing the scope of scanned documents, and significantly improving retrieval efficiency.lt proves to be effective and feasible through experiment.%从海量文档中快速有效地搜索到相似文档是一个重要且耗时的问题.现有的文档相似性搜索算法是先找出候选文档集,再对候选文档进行相关性排序,找出最相关的文档.提出了一种基于文档拓扑的相似性搜索算法-Hub-N,将文档相似性搜索问题转化为图搜索问题,应用相应的剪枝技术,缩小了扫描文档的范围,提高了搜索效率.通过实验验证了算法的有效性和可行性.

  5. Novel DOCK clique driven 3D similarity database search tools for molecule shape matching and beyond: adding flexibility to the search for ligand kin.

    Good, Andrew C

    2007-10-01

    With readily available CPU power and copious disk storage, it is now possible to undertake rapid comparison of 3D properties derived from explicit ligand overlay experiments. With this in mind, shape software tools originally devised in the 1990s are revisited, modified and applied to the problem of ligand database shape comparison. The utility of Connolly surface data is highlighted using the program MAKESITE, which leverages surface normal data to a create ligand shape cast. This cast is applied directly within DOCK, allowing the program to be used unmodified as a shape searching tool. In addition, DOCK has undergone multiple modifications to create a dedicated ligand shape comparison tool KIN. Scoring has been altered to incorporate the original incarnation of Gaussian function derived shape description based on STO-3G atomic electron density. In addition, a tabu-like search refinement has been added to increase search speed by removing redundant starting orientations produced during clique matching. The ability to use exclusion regions, again based on Gaussian shape overlap, has also been integrated into the scoring function. The use of both DOCK with MAKESITE and KIN in database screening mode is illustrated using a published ligand shape virtual screening template. The advantages of using a clique-driven search paradigm are highlighted, including shape optimization within a pharmacophore constrained framework, and easy incorporation of additional scoring function modifications. The potential for further development of such methods is also discussed. PMID:17482856

  6. Search for reducing methodology of acceleration aging time in reversed sequential application of heat and radiation using numerical computational program

    Two consecutive numerical calculations on degradation of polymeric insulations under thermal and radiation environment are carried out to simulate so-called reversal sequential acceleration test. The calculation is aiming at searching the test conditions which provide material damage equivalent to the case of simultaneous exposure of heat and radiation. The total aging time in reversal sequential method becomes the shortest if all amount of target degradation is assigned to radiation process with the strongest allowable dose rate. If the total time becomes shorter than this using the heating process, radiation process in any dose rate conditions would prolong the testing time. (author)

  7. PHASE-RESOLVED INFRARED SPECTROSCOPY AND PHOTOMETRY OF V1500 CYGNI, AND A SEARCH FOR SIMILAR OLD CLASSICAL NOVAE

    We present phase-resolved near-infrared photometry and spectroscopy of the classical nova (CN) V1500 Cyg to explore whether cyclotron emission is present in this system. While the spectroscopy do not indicate the presence of discrete cyclotron harmonic emission, the light curves suggest that a sizable fraction of its near-infrared fluxes are due to this component. The light curves of V1500 Cyg appear to remain dominated by emission from the heated face of the secondary star in this system. We have used infrared spectroscopy and photometry to search for other potential magnetic systems among old CNe. We have found that the infrared light curves of V1974 Cyg superficially resemble those of V1500 Cyg, suggesting a highly irradiated companion. The old novae V446 Her and QV Vul have light curves with large amplitude variations like those seen in polars, suggesting they might have magnetic primaries. We extract photometry for 79 old novae from the Two Micron All Sky Survey Point Source Catalog and use those data to derive the mean, un-reddened infrared colors of quiescent novae. We also extract WISE data for these objects and find that 45 of them were detected. Surprisingly, a number of these systems were detected in the WISE 22 μm band. While two of those objects produced significant dust shells (V705 Cas and V445 Pup), the others did not. It appears that line emission from their ionized ejected shells is the most likely explanation for those detections

  8. Accelerator facilities probing the physics of scales: the 12 GeV upgrade of CEBAF in search of 'Quark Confinement'

    We will identify the various accelerator-based US facilities in operation and/or planned for exploring Nuclear/Particle Physics at different scales from the multibody Nucleon-Nucleon Force. Rare Nuclear Isotopes and Nuclear Astrophysics on one hand through facilities probing 'Hadronic Physics' deep inside a nucleon (such as the search for 'pentaquark' and strange matter) to colliders in search of 'new states' of nuclear matter (such as the 'quark-gluon plasma' or 'strongly interacting nuclear liquid'). In particular, we will explore in some depth the science behind the 'GlueX' experiment planned in Hall D of Jefferson Lab's upgraded 12 GeV Continuous Electron Beam Accelerator Facility (CEBAF). There, coherent Bremsstrahlung photons of 9 GeV energy, obtained from a continuous string of 12 GeV electrons stopped by a diamond crystal, will be used to photoexcite 'exotic' mesons where the degree of freedom of the strong gluonic force binding the quark-antiquark pair is excited. A careful partial wave analysis eliminating the vibrational and rotational 'quark' degrees of freedom of the 'di-quark' molecule and an analysis of the forbidden J'PC' quantum states will reveal the signal of new truly 'exotic' quantum states with pure gluonic information. The exotic meson spectroscopy will allow 'mapping the strong force' that confines quarks as a 'function of distance between quarks', with the search for a possible ultimate 'glueball' state within reach. The experiment will firmly establish QCD experimentally in the nonperturbative 'confinement regime', complementing the perturbative QCD established firmly in the regime of 'asymptotic freedom', recognized via the Nobel Prize in 2004. (author)

  9. Search for magnetic fields in particle-accelerating colliding-wind binaries

    Neiner, C.; Grunhut, J.; Leroy, B; De Becker, Michaël; Rauw, Grégor

    2014-01-01

    Some colliding-wind massive binaries, called particle-accelerating colliding-wind binaries (PACWB), exhibit synchrotron radio emission, which is assumed to be generated by a stellar magnetic field. However, no measurement of magnetic fields in these stars has ever been performed. We aim at quantifying the possible stellar magnetic fields present in PACWB to provide constraints for models. We gathered 21 high-resolution spectropolarimetric observations of 9 PACWB available in the ESPaDOnS, Nar...

  10. Tempest: Accelerated MS/MS Database Search Software for Heterogeneous Computing Platforms.

    Adamo, Mark E; Gerber, Scott A

    2016-01-01

    MS/MS database search algorithms derive a set of candidate peptide sequences from in silico digest of a protein sequence database, and compute theoretical fragmentation patterns to match these candidates against observed MS/MS spectra. The original Tempest publication described these operations mapped to a CPU-GPU model, in which the CPU (central processing unit) generates peptide candidates that are asynchronously sent to a discrete GPU (graphics processing unit) to be scored against experimental spectra in parallel. The current version of Tempest expands this model, incorporating OpenCL to offer seamless parallelization across multicore CPUs, GPUs, integrated graphics chips, and general-purpose coprocessors. Three protocols describe how to configure and run a Tempest search, including discussion of how to leverage Tempest's unique feature set to produce optimal results. © 2016 by John Wiley & Sons, Inc. PMID:27603022

  11. Throughput Analysis for a High-Performance FPGA-Accelerated Real-Time Search Application

    Wim Vanderbauwhede

    2012-01-01

    Full Text Available We propose an FPGA design for the relevancy computation part of a high-throughput real-time search application. The application matches terms in a stream of documents against a static profile, held in off-chip memory. We present a mathematical analysis of the throughput of the application and apply it to the problem of scaling the Bloom filter used to discard nonmatches.

  12. QAR数据多维子序列的相似性搜索%Similarity search for multidimensional QAR data subsequence

    杨慧; 张国振

    2013-01-01

    High dimensionality of QAR and the uncertain relevance among them which make the method to do the similarity search for time series in the low dimensionality are no longer applicable in such situation. Taking into account the specificity of the civil aviation industry, with the similarity search for QAR to ascertain the plane faults requires a special definition of the similarity. In this paper, expertise and analytic hierarchy process algorithm are combined to be used to calculate the weightiness of different dimensionalities for the plane fault. It translates the QAR data with the symbolic method, and then builds a k-d tree index, which makes it possible to do the similarity search on multidimensional QAR data subsequences. Shape and distance are used toghther to define similarity. The high precision and the low cost are proved by the experiments in this paper.%QAR数据的高维度以及维度之间不确定的相互关联性,使得原有低维空间上度量时间序列的相似性的方法不再适用,另一方面由于民航行业的特殊性,利用QAR数据进行相似性搜索来确定飞行故障,对相似性的定义也有特殊的要求.通过专家经验结合一种层次分析算法来确定飞行故障所关联的属性维度的重要性,对QAR数据的多维子序列进行符号化表示,并利用k-d树的特殊性质建立索引,使QAR数据多维子序列的快速相似性搜索成为可能,结合形状和距离对相似性进行定义和度量,实验证明查找速度快,准确度较为满意.

  13. Accelerated equilibrium core composition search using a new MCNP-based simulator

    MocDown is a new Monte Carlo depletion and recycling simulator which couples neutron transport with MCNP and transmutation with ORIGEN. This modular approach to depletion allows for flexible operation by incorporating the accelerated progression of a complex fuel processing scheme towards equilibrium and by allowing for the online coupling of thermo-fluids feedback. MocDown also accounts for the variation of decay heat with fuel isotopics evolution. In typical cases, MocDown requires just over a day to find the equilibrium core composition for a multi-recycling fuel cycle, with a self-consistent thermo-fluids solution-a task that required between one and two weeks using previous Monte Carlo-based approaches. (authors)

  14. Accelerated equilibrium core composition search using a new MCNP-based simulator

    Seifried, Jeffrey E.; Gorman, Phillip M.; Vujic, Jasmina L.; Greenspan, Ehud

    2014-06-01

    MocDown is a new Monte Carlo depletion and recycling simulator which couples neutron transport with MCNP and transmutation with ORIGEN. This modular approach to depletion allows for flexible operation by incorporating the accelerated progression of a complex fuel processing scheme towards equilibrium and by allowing for the online coupling of thermo-fluids feedback. MocDown also accounts for the variation of decay heat with fuel isotopics evolution. In typical cases, MocDown requires just over a day to find the equilibrium core composition for a multi-recycling fuel cycle, with a self-consistent thermo-fluids solution-a task that required between one and two weeks using previous Monte Carlo-based approaches.

  15. SPOT-Ligand: Fast and effective structure-based virtual screening by binding homology search according to ligand and receptor similarity.

    Yang, Yuedong; Zhan, Jian; Zhou, Yaoqi

    2016-07-01

    Structure-based virtual screening usually involves docking of a library of chemical compounds onto the functional pocket of the target receptor so as to discover novel classes of ligands. However, the overall success rate remains low and screening a large library is computationally intensive. An alternative to this "ab initio" approach is virtual screening by binding homology search. In this approach, potential ligands are predicted based on similar interaction pairs (similarity in receptors and ligands). SPOT-Ligand is an approach that integrates ligand similarity by Tanimoto coefficient and receptor similarity by protein structure alignment program SPalign. The method was found to yield a consistent performance in DUD and DUD-E docking benchmarks even if model structures were employed. It improves over docking methods (DOCK6 and AUTODOCK Vina) and has a performance comparable to or better than other binding-homology methods (FINDsite and PoLi) with higher computational efficiency. The server is available at http://sparks-lab.org. © 2016 Wiley Periodicals, Inc. PMID:27074979

  16. Accelerator mass spectrometry of actinides and the search for superheavy elements

    In the 1960s nuclear shell model calculations indicated an increased stability of superheavy closed-shell nuclides beyond any known species. This region was quickly nicknamed island of stability', and half-lives up to 109 years were predicted for some nuclides. Assuming their presence in the Early Solar System, the predicted half-lives would be sufficiently long to find traces of these nuclides in natural materials today. Within the last decades numerous experiments - utilizing different measurement techniques - were conducted to detect superheavy elements (SHEs) in nature - all with negative results. Appreciable technical progress in Accelerator Mass Spectrometry (AMS) within recent years triggered new attempts to find SHEs in natural materials. AMS is considered to be the 'technique of choice' for the detection of long-lived radionuclides at ultra-low abundances. The outstanding selectivity of AMS allowed the investigation of chemically untreated natural samples, preventing a priori an unintended separation of SHEs in chemical preparations, which are required for other measurement techniques. For the first time the 'Vienna Environmental Research Accelerator' (VERA) facility was set up for AMS measurements in the mass range of A = 288-300 amu. Altogether 30 nuclides in the vicinity of the 'island of stability' were investigated. Sample material extracted from natural ores containing Pb or Bi and nuggets of Pt and Au was used in these measurements. Since no unambiguous events were detected, upper limits for the abundance of those nuclides within the sample matrix in the range of 10-12 to 10-15 (relative to the carrier matrix atoms) could be established. When the SHE project started at VERA, the detection of a long-lived superheavy ion species with A = 292 in thorium was reported by the group of Marinov et al. in Jerusalem performed by means of inductively coupled plasma sector field mass spectrometry (ICPSF-MS). The group also reported on the detection of four long

  17. Similarity Search in Document Collections

    Jordanov, Dimitar Dimitrov

    2009-01-01

    Hlavním cílem této práce je odhadnout výkonnost volně šířeni balík  Sémantický Vektory a třída MoreLikeThis z balíku Apache Lucene. Tato práce nabízí porovnání těchto dvou přístupů a zavádí metody, které mohou vést ke zlepšení kvality vyhledávání.

  18. Search for magnetic fields in particle-accelerating colliding-wind binaries

    Neiner, C; Leroy, B; De Becker, M; Rauw, G

    2014-01-01

    Some colliding-wind massive binaries, called particle-accelerating colliding-wind binaries (PACWB), exhibit synchrotron radio emission, which is assumed to be generated by a stellar magnetic field. However, no measurement of magnetic fields in these stars has ever been performed. We aim at quantifying the possible stellar magnetic fields present in PACWB to provide constraints for models. We gathered 21 high-resolution spectropolarimetric observations of 9 PACWB available in the ESPaDOnS, Narval and HarpsPol archives. We analysed these observations with the Least Squares Deconvolution method. We separated the binary spectral components when possible. No magnetic signature is detected in any of the 9 PACWB stars and all longitudinal field measurements are compatible with 0 G. We derived the upper field strength of a possible field that could have remained hidden in the noise of the data. While the data are not very constraining for some stars, for several stars we could derive an upper limit of the polar field...

  19. Search for magnetic fields in particle-accelerating colliding-wind binaries

    Neiner, C.; Grunhut, J.; Leroy, B.; De Becker, M.; Rauw, G.

    2015-03-01

    Context. Some colliding-wind massive binaries, called particle-accelerating colliding-wind binaries (PACWB), exhibit synchrotron radio emission, which is assumed to be generated by a stellar magnetic field. However, no measurement of magnetic fields in these stars has ever been performed. Aims: We aim at quantifying the possible stellar magnetic fields present in PACWB to provide constraints for models. Methods: We gathered 21 high-resolution spectropolarimetric observations of 9 PACWB available in the ESPaDOnS, Narval and HarpsPol archives. We analysed these observations with the least squares deconvolution method. We separated the binary spectral components when possible. Results: No magnetic signature is detected in any of the 9 PACWB stars and all longitudinal field measurements are compatible with 0 G. We derived the upper field strength of a possible field that could have remained hidden in the noise of the data. While the data are not very constraining for some stars, for several stars we could derive an upper limit of the polar field strength of the order of 200 G. Conclusions: We can therefore exclude the presence of strong or moderate stellar magnetic fields in PACWB, typical of the ones present in magnetic massive stars. Weak magnetic fields could however be present in these objects. These observational results provide the first quantitative constraints for future models of PACWB. Based on archival observations obtained at the Télescope Bernard Lyot (USR5026) operated by the Observatoire Midi-Pyrénées, Université de Toulouse (Paul Sabatier), Centre National de la Recherche Scientifique (CNRS) of France, at the Canada-France-Hawaii Telescope (CFHT) operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the CNRS of France, and the University of Hawaii, and at the European Southern Observatory (ESO), Chile.

  20. Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching.

    Parkesh, Raman; Childs-Disney, Jessica L; Nakamori, Masayuki; Kumar, Amit; Wang, Eric; Wang, Thomas; Hoskins, Jason; Tran, Tuan; Housman, David; Thornton, Charles A; Disney, Matthew D

    2012-03-14

    Myotonic dystrophy type 1 (DM1) is a triplet repeating disorder caused by expanded CTG repeats in the 3'-untranslated region of the dystrophia myotonica protein kinase (DMPK) gene. The transcribed repeats fold into an RNA hairpin with multiple copies of a 5'CUG/3'GUC motif that binds the RNA splicing regulator muscleblind-like 1 protein (MBNL1). Sequestration of MBNL1 by expanded r(CUG) repeats causes splicing defects in a subset of pre-mRNAs including the insulin receptor, the muscle-specific chloride ion channel, sarco(endo)plasmic reticulum Ca(2+) ATPase 1, and cardiac troponin T. Based on these observations, the development of small-molecule ligands that target specifically expanded DM1 repeats could be of use as therapeutics. In the present study, chemical similarity searching was employed to improve the efficacy of pentamidine and Hoechst 33258 ligands that have been shown previously to target the DM1 triplet repeat. A series of in vitro inhibitors of the RNA-protein complex were identified with low micromolar IC(50)'s, which are >20-fold more potent than the query compounds. Importantly, a bis-benzimidazole identified from the Hoechst query improves DM1-associated pre-mRNA splicing defects in cell and mouse models of DM1 (when dosed with 1 mM and 100 mg/kg, respectively). Since Hoechst 33258 was identified as a DM1 binder through analysis of an RNA motif-ligand database, these studies suggest that lead ligands targeting RNA with improved biological activity can be identified by using a synergistic approach that combines analysis of known RNA-ligand interactions with chemical similarity searching. PMID:22300544

  1. Improving Limit Surface Search Algorithms in RAVEN Using Acceleration Schemes: Level II Milestone

    Alfonsi, Andrea [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Rabiti, Cristian [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Cogliati, Joshua Joseph [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Sen, Ramazan Sonat [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Smith, Curtis Lee [Idaho National Laboratory (INL), Idaho Falls, ID (United States)

    2015-07-01

    , subject of the analysis. These methodologies are named, in the RAVEN environment, adaptive sampling strategies. These methodologies infer system responses from surrogate models constructed from already existing samples (produced using high fidelity simulations) and suggest the most relevant location (coordinate in the input space) of the next sampling point to be explored in the uncertain/parametric domain. When using those methodologies, it is possible to understand features of the system response with a small number of carefully selected samples. This report focuses on the development and improvement of the limit surface search. The limit surface is an important concept in system reliability analysis. Without going into the details, which will be covered later in the report, the limit surface could be briefly described as an hyper-surface in the system uncertainty/parametric space separating the regions leading to a prescribed system outcome. For example, if the uncertainty/parametric space is the one generated by the reactor power level and the duration of the batteries, the system is a nuclear power plant and the system outcome discriminating variable is the clad failure in a station blackout scenario, then the limit surface separates the combinations of reactor power level and battery duration that lead to clad failure from the ones that do not.

  2. Improving Limit Surface Search Algorithms in RAVEN Using Acceleration Schemes: Level II Milestone

    system, subject of the analysis. These methodologies are named, in the RAVEN environment, adaptive sampling strategies. These methodologies infer system responses from surrogate models constructed from already existing samples (produced using high fidelity simulations) and suggest the most relevant location (coordinate in the input space) of the next sampling point to be explored in the uncertain/parametric domain. When using those methodologies, it is possible to understand features of the system response with a small number of carefully selected samples. This report focuses on the development and improvement of the limit surface search. The limit surface is an important concept in system reliability analysis. Without going into the details, which will be covered later in the report, the limit surface could be briefly described as an hyper-surface in the system uncertainty/parametric space separating the regions leading to a prescribed system outcome. For example, if the uncertainty/parametric space is the one generated by the reactor power level and the duration of the batteries, the system is a nuclear power plant and the system outcome discriminating variable is the clad failure in a station blackout scenario, then the limit surface separates the combinations of reactor power level and battery duration that lead to clad failure from the ones that do not.

  3. Compression-based similarity

    Vitányi, Paul

    2011-01-01

    First we consider pair-wise distances for literal objects consisting of finite binary files. These files are taken to contain all of their meaning, like genomes or books. The distances are based on compression of the objects concerned, normalized, and can be viewed as similarity distances. Second, we consider pair-wise distances between names of objects, like "red" or "christianity." In this case the distances are based on searches of the Internet. Such a search can be performed by any search...

  4. Current trends in non-accelerator particle physics: 1, Neutrino mass and oscillation. 2, High energy neutrino astrophysics. 3, Detection of dark matter. 4, Search for strange quark matter. 5, Magnetic monopole searches

    This report is a compilation of papers reflecting current trends in non-accelerator particle physics, corresponding to talks that its author was invited to present at the Workshop on Tibet Cosmic Ray Experiment and Related Physics Topics held in Beijing, China, April 4--13, 1995. The papers are entitled 'Neutrino Mass and Oscillation', 'High Energy Neutrino Astrophysics', 'Detection of Dark Matter', 'Search for Strange Quark Matter', and 'Magnetic Monopole Searches'. The report is introduced by a survey of the field and a brief description of each of the author's papers

  5. Current trends in non-accelerator particle physics: 1, Neutrino mass and oscillation. 2, High energy neutrino astrophysics. 3, Detection of dark matter. 4, Search for strange quark matter. 5, Magnetic monopole searches

    He, Yudong [California Univ., Berkeley, CA (United States)]|[Lawrence Berkeley Lab., CA (United States)

    1995-07-01

    This report is a compilation of papers reflecting current trends in non-accelerator particle physics, corresponding to talks that its author was invited to present at the Workshop on Tibet Cosmic Ray Experiment and Related Physics Topics held in Beijing, China, April 4--13, 1995. The papers are entitled `Neutrino Mass and Oscillation`, `High Energy Neutrino Astrophysics`, `Detection of Dark Matter`, `Search for Strange Quark Matter`, and `Magnetic Monopole Searches`. The report is introduced by a survey of the field and a brief description of each of the author`s papers.

  6. Neural circuits of eye movements during performance of the visual exploration task, which is similar to the responsive search score task, in schizophrenia patients and normal subjects

    Abnormal exploratory eye movements have been studied as a biological marker for schizophrenia. Using functional MRI (fMRI), we investigated brain activations of 12 healthy and 8 schizophrenic subjects during performance of a visual exploration task that is similar to the responsive search score task to clarify the neural basis of the abnormal exploratory eye movement. Performance data, such as the number of eye movements, the reaction time, and the percentage of correct answers showed no significant differences between the two groups. Only the normal subjects showed activations at the bilateral thalamus and the left anterior medial frontal cortex during the visual exploration tasks. In contrast, only the schizophrenic subjects showed activations at the right anterior cingulate gyms during the same tasks. The activation at the different locations between the two groups, the left anterior medial frontal cortex in normal subjects and the right anterior cingulate gyrus in schizophrenia subjects, was explained by the feature of the visual tasks. Hypoactivation at the bilateral thalamus supports a dysfunctional filtering theory of schizophrenia. (author)

  7. Gesture Recognition from Data Streams of Human Motion Sensor Using Accelerated PSO Swarm Search Feature Selection Algorithm

    Simon Fong

    2015-01-01

    Full Text Available Human motion sensing technology gains tremendous popularity nowadays with practical applications such as video surveillance for security, hand signing, and smart-home and gaming. These applications capture human motions in real-time from video sensors, the data patterns are nonstationary and ever changing. While the hardware technology of such motion sensing devices as well as their data collection process become relatively mature, the computational challenge lies in the real-time analysis of these live feeds. In this paper we argue that traditional data mining methods run short of accurately analyzing the human activity patterns from the sensor data stream. The shortcoming is due to the algorithmic design which is not adaptive to the dynamic changes in the dynamic gesture motions. The successor of these algorithms which is known as data stream mining is evaluated versus traditional data mining, through a case of gesture recognition over motion data by using Microsoft Kinect sensors. Three different subjects were asked to read three comic strips and to tell the stories in front of the sensor. The data stream contains coordinates of articulation points and various positions of the parts of the human body corresponding to the actions that the user performs. In particular, a novel technique of feature selection using swarm search and accelerated PSO is proposed for enabling fast preprocessing for inducing an improved classification model in real-time. Superior result is shown in the experiment that runs on this empirical data stream. The contribution of this paper is on a comparative study between using traditional and data stream mining algorithms and incorporation of the novel improved feature selection technique with a scenario where different gesture patterns are to be recognized from streaming sensor data.

  8. Textual Spatial Cosine Similarity

    Crocetti, Giancarlo

    2015-01-01

    When dealing with document similarity many methods exist today, like cosine similarity. More complex methods are also available based on the semantic analysis of textual information, which are computationally expensive and rarely used in the real time feeding of content as in enterprise-wide search environments. To address these real-time constraints, we developed a new measure of document similarity called Textual Spatial Cosine Similarity, which is able to detect similitude at the semantic ...

  9. Similarity Search in Data Stream with Adaptive Segmental Approximations%基于适应性分段估计的数据流相似性搜索

    吴枫; 仲妍; 吴泉源; 贾焰; 杨树强

    2009-01-01

    Similarity search has attracted many researchers from various communities (real-time stock quotes, network security, sensor networks). Due to the infinite, continuous, fast and real-time properties of the data from these communities, a method is needed for online similarity search in data stream. This paper first proposes the lower bound function LB_seg_WF_(global) for DTW (dynamic time warping) in the presence of global warping constraints and LB_seg_WF for DTW without global warping constraints, which are not applied to any index structures. They are segmented DTW techniques, and can be applied to sequences and queries of varying lengths in data stream. Next, several tighter lower bounds are proposed to improve the approximate degree of the LB_seg_WF_(global) and LB_seg_WF. Finally, to deal with the possible continuously non-effective problem of LB_seg_WF_(global) or LB_seg_WF in data stream, it is believed that lower-bound LB_WF_(global) (in the presence of global warping constraints) and lower-bound LB_WF, upper-bound UB_WF (without global warping constraints) can fast estimate DTW and hence reduce a lot of redundant computations by incrementally computing. The theoretical analysis and statistical experiments confirm the validity of the proposed methods.%相似性搜索在股票交易行情、网络安全、传感器网络等众多领域应用广泛.由于这些领域中产生的数据具有无限的、连续的、快速的、实时的特性,所以需要适合数据流上的在线相似性搜索算法.首先,在具有或不具有全局约束条件下,分别提出了没有索引结构的DTW(dynamic time warping)下限函数LB_seg_WF_(global)和LB_seg_WF,它们是一种分段DTW技术,能够处理数据流上的非等长序列间在线相似性匹配问题.然后,为了进一步提高LB_seg_WF_(global)和LB_seg_WF的近似程度,提出了一系列的改进方法.最后,针对流上使用LB_seg_WF_(global)或LB_seg_WF可能会出现连续失效的情况,分别提

  10. Concept Search

    Giunchiglia, Fausto; Kharkevich, Uladzimir; Zaihrayeu, Ilya

    2008-01-01

    In this paper we present a novel approach, called Concept Search, which extends syntactic search, i.e., search based on the computation of string similarity between words, with semantic search, i.e., search based on the computation of semantic relations between concepts. The key idea of Concept Search is to operate on complex concepts and to maximally exploit the semantic information available, reducing to syntactic search only when necessary, i.e., when no semantic information is available. ...

  11. Modal Similarity

    Vigo , Dr. Ronaldo

    2009-01-01

    Just as Boolean rules define Boolean categories, the Boolean operators define higher-order Boolean categories referred to as modal categories. We examine the similarity order between these categories and the standard category of logical identity (i.e. the modal category defined by the biconditional or equivalence operator). Our goal is 4-fold: first, to introduce a similarity measure for determining this similarity order; second, to show that such a measure is a good predictor of the similari...

  12. CUDAMPF: a multi-tiered parallel framework for accelerating protein sequence search in HMMER on CUDA-enabled GPU

    Jiang, Hanyu; Ganesan, Narayan

    2016-01-01

    Background HMMER software suite is widely used for analysis of homologous protein and nucleotide sequences with high sensitivity. The latest version of hmmsearch in HMMER 3.x, utilizes heuristic-pipeline which consists of MSV/SSV (Multiple/Single ungapped Segment Viterbi) stage, P7Viterbi stage and the Forward scoring stage to accelerate homology detection. Since the latest version is highly optimized for performance on modern multi-core CPUs with SSE capabilities, only a few acceleration att...

  13. Combination of 2D/3D Ligand-Based Similarity Search in Rapid Virtual Screening from Multimillion Compound Repositories. Selection and Biological Evaluation of Potential PDE4 and PDE5 Inhibitors

    Krisztina Dobi

    2014-05-01

    Full Text Available Rapid in silico selection of target focused libraries from commercial repositories is an attractive and cost effective approach. If structures of active compounds are available rapid 2D similarity search can be performed on multimillion compound databases but the generated library requires further focusing by various 2D/3D chemoinformatics tools. We report here a combination of the 2D approach with a ligand-based 3D method (Screen3D which applies flexible matching to align reference and target compounds in a dynamic manner and thus to assess their structural and conformational similarity. In the first case study we compared the 2D and 3D similarity scores on an existing dataset derived from the biological evaluation of a PDE5 focused library. Based on the obtained similarity metrices a fusion score was proposed. The fusion score was applied to refine the 2D similarity search in a second case study where we aimed at selecting and evaluating a PDE4B focused library. The application of this fused 2D/3D similarity measure led to an increase of the hit rate from 8.5% (1st round, 47% inhibition at 10 µM to 28.5% (2nd round at 50% inhibition at 10 µM and the best two hits had 53 nM inhibitory activities.

  14. Accelerators and Dinosaurs

    Turner, Michael Stanley

    2003-01-01

    Using naturally occuring particles on which to research might have made accelerators become extinct. But in fact, results from astrophysics have made accelerator physics even more important. Not only are accelerators used in hospitals but they are also being used to understand nature's inner workings by searching for Higgs bosons, CP violation, neutrino mass and dark matter (2 pages)

  15. Cognitive residues of similarity

    OToole, Stephanie; Keane, Mark T.

    2013-01-01

    What are the cognitive after-effects of making a similarity judgement? What, cognitively, is left behind and what effect might these residues have on subsequent processing? In this paper, we probe for such after-effects using a visual search task, performed after a task in which pictures of real-world objects were compared. So, target objects were first presented in a comparison task (e.g., rate the similarity of this object to another) thus, presumably, modifying some of their features befor...

  16. Accelerated Cure Project for Multiple Sclerosis

    ... main content Accelerating research toward a cure for multiple sclerosis Home Contact Us Search form Search Connect Volunteer ... is to accelerate efforts toward a cure for multiple sclerosis by rapidly advancing research that determines its causes ...

  17. Search for major genes with progeny test data to accelerate the development of genetically superior loblolly pine

    NCSU

    2003-12-30

    This research project is to develop a novel approach that fully utilized the current breeding materials and genetic test information available from the NCSU-Industry Cooperative Tree Improvement Program to identify major genes that are segregating for growth and disease resistance in loblolly pine. If major genes can be identified in the existing breeding population, they can be utilized directly in the conventional loblolly pine breeding program. With the putative genotypes of parents identified, tree breeders can make effective decisions on management of breeding populations and operational deployment of genetically superior trees. Forest productivity will be significantly enhanced if genetically superior genotypes with major genes for economically important traits could be deployed in an operational plantation program. The overall objective of the project is to develop genetic model and analytical methods for major gene detection with progeny test data and accelerate the development of genetically superior loblolly pine. Specifically, there are three main tasks: (1) Develop genetic models for major gene detection and implement statistical methods and develop computer software for screening progeny test data; (2) Confirm major gene segregation with molecular markers; and (3) Develop strategies for using major genes for tree breeding.

  18. GPU-Accelerated Text Mining

    Cui, Xiaohui [ORNL; Mueller, Frank [North Carolina State University; Zhang, Yongpeng [ORNL; Potok, Thomas E [ORNL

    2009-01-01

    Accelerating hardware devices represent a novel promise for improving the performance for many problem domains but it is not clear for which domains what accelerators are suitable. While there is no room in general-purpose processor design to significantly increase the processor frequency, developers are instead resorting to multi-core chips duplicating conventional computing capabilities on a single die. Yet, accelerators offer more radical designs with a much higher level of parallelism and novel programming environments. This present work assesses the viability of text mining on CUDA. Text mining is one of the key concepts that has become prominent as an effective means to index the Internet, but its applications range beyond this scope and extend to providing document similarity metrics, the subject of this work. We have developed and optimized text search algorithms for GPUs to exploit their potential for massive data processing. We discuss the algorithmic challenges of parallelization for text search problems on GPUs and demonstrate the potential of these devices in experiments by reporting significant speedups. Our study may be one of the first to assess more complex text search problems for suitability for GPU devices, and it may also be one of the first to exploit and report on atomic instruction usage that have recently become available in NVIDIA devices.

  19. GPU-Accelerated Text Mining

    Accelerating hardware devices represent a novel promise for improving the performance for many problem domains but it is not clear for which domains what accelerators are suitable. While there is no room in general-purpose processor design to significantly increase the processor frequency, developers are instead resorting to multi-core chips duplicating conventional computing capabilities on a single die. Yet, accelerators offer more radical designs with a much higher level of parallelism and novel programming environments. This present work assesses the viability of text mining on CUDA. Text mining is one of the key concepts that has become prominent as an effective means to index the Internet, but its applications range beyond this scope and extend to providing document similarity metrics, the subject of this work. We have developed and optimized text search algorithms for GPUs to exploit their potential for massive data processing. We discuss the algorithmic challenges of parallelization for text search problems on GPUs and demonstrate the potential of these devices in experiments by reporting significant speedups. Our study may be one of the first to assess more complex text search problems for suitability for GPU devices, and it may also be one of the first to exploit and report on atomic instruction usage that have recently become available in NVIDIA devices

  20. Gene functional similarity search tool (GFSST)

    Russo James J; Sheng Huitao; Zhang Jinghui; Zhang Peisen; Osborne Brian; Buetow Kenneth

    2006-01-01

    Abstract Background With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomicroarray chips, more and more genes and their products have been discovered and their functions have begun to be understood. Increasing amounts of data about genes, gene products and their functions have been stored in databases. To facilitate selection of candidate genes for gene-disease research, genetic as...

  1. Personalized Search

    AUTHOR|(SzGeCERN)749939

    2015-01-01

    As the volume of electronically available information grows, relevant items become harder to find. This work presents an approach to personalizing search results in scientific publication databases. This work focuses on re-ranking search results from existing search engines like Solr or ElasticSearch. This work also includes the development of Obelix, a new recommendation system used to re-rank search results. The project was proposed and performed at CERN, using the scientific publications available on the CERN Document Server (CDS). This work experiments with re-ranking using offline and online evaluation of users and documents in CDS. The experiments conclude that the personalized search result outperform both latest first and word similarity in terms of click position in the search result for global search in CDS.

  2. A measurement of hadron production cross sections for the simulation of accelerator neutrino beams and a search for muon-neutrino to electron-neutrino oscillations in the delta m**2 about equals 1-eV**2 region

    Schmitz, David W.; /Columbia U.

    2008-01-01

    A measurement of hadron production cross-sections for the simulation of accelerator neutrino beams and a search for muon neutrino to electron neutrino oscillations in the {Delta}m{sup 2} {approx} 1 eV{sup 2} region. This dissertation presents measurements from two different high energy physics experiments with a very strong connection: the Hadron Production (HARP) experiment located at CERN in Geneva, Switzerland, and the Mini Booster Neutrino Experiment (Mini-BooNE) located at Fermilab in Batavia, Illinois.

  3. The search for evidence of particle acceleration at SN 1987A in MeV to PeV γ rays

    Young supernova remnants may be bright sources of energetic photons and neutrinos, which are produced by collisions of particles accelerated inside the remnant. The new supernova 1987A has led to renewed interest in the subject, with several papers discussing the possibility of observing high-energy neutrinos and photons from this supernova. This paper reviews the prospects for production of observable signatures of particle acceleration in SN1987A and their potential implications for energetic processes inside young, Type II supernovae. The bolometric light curve of SN1987A can place a strong upper limit on the power from a source other than the energy released in the radioactive decay chain of 56Ni → 56CO → 56Fe. This in turn limits the amount of power from a central source, such as a pulsar, that might accelerate particles. However, it is still possible that acceleration may be occurring in SN1987A at detectable levels

  4. A Denoising Autoencoder that Guides Stochastic Search

    Churchill, Alexander W.; Sigtia, Siddharth; Fernando, Chrisantha

    2014-01-01

    An algorithm is described that adaptively learns a non-linear mutation distribution. It works by training a denoising autoencoder (DA) online at each generation of a genetic algorithm to reconstruct a slowly decaying memory of the best genotypes so far. A compressed hidden layer forces the autoencoder to learn hidden features in the training set that can be used to accelerate search on novel problems with similar structure. Its output neurons define a probability distribution that we sample f...

  5. Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors.

    Eman M Dokla

    Full Text Available This study provides a comprehensive computational procedure for the discovery of novel urea-based antineoplastic kinase inhibitors while focusing on diversification of both chemotype and selectivity pattern. It presents a systematic structural analysis of the different binding motifs of urea-based kinase inhibitors and the corresponding configurations of the kinase enzymes. The computational model depends on simultaneous application of two protocols. The first protocol applies multiple consecutive validated virtual screening filters including SMARTS, support vector-machine model (ROC = 0.98, Bayesian model (ROC = 0.86 and structure-based pharmacophore filters based on urea-based kinase inhibitors complexes retrieved from literature. This is followed by hits profiling against different extended electron distribution (XED based field templates representing different kinase targets. The second protocol enables cancericidal activity verification by using the algorithm of feature trees (Ftrees similarity searching against NCI database. Being a proof-of-concept study, this combined procedure was experimentally validated by its utilization in developing a novel series of urea-based derivatives of strong anticancer activity. This new series is based on 3-benzylbenzo[d]thiazol-2(3H-one scaffold which has interesting chemical feasibility and wide diversification capability. Antineoplastic activity of this series was assayed in vitro against NCI 60 tumor-cell lines showing very strong inhibition of GI(50 as low as 0.9 uM. Additionally, its mechanism was unleashed using KINEX™ protein kinase microarray-based small molecule inhibitor profiling platform and cell cycle analysis showing a peculiar selectivity pattern against Zap70, c-src, Mink1, csk and MeKK2 kinases. Interestingly, it showed activity on syk kinase confirming the recent studies finding of the high activity of diphenyl urea containing compounds against this kinase. Allover, the new series

  6. Can Accelerators Accelerate Learning?

    The 'Young Talented' education program developed by the Brazilian State Funding Agency (FAPERJ)[1] makes it possible for high-schools students from public high schools to perform activities in scientific laboratories. In the Atomic and Molecular Physics Laboratory at Federal University of Rio de Janeiro (UFRJ), the students are confronted with modern research tools like the 1.7 MV ion accelerator. Being a user-friendly machine, the accelerator is easily manageable by the students, who can perform simple hands-on activities, stimulating interest in physics, and getting the students close to modern laboratory techniques.

  7. Accelerated simulated tempering

    We propose a new stochastic global optimization method by accelerating the simulated tempering scheme with random walks executed on a temperature ladder with various transition step sizes. By suitably choosing the length of the transition steps, the accelerated scheme enables the search process to execute large jumps and escape entrapment in local minima, while retaining the capability to explore local details, whenever warranted. Our simulations confirm the expected improvements and show that the accelerated simulated tempering scheme has a much faster convergence to the target distribution than Geyer and Thompson's simulated tempering algorithm and exhibits accuracy comparable to the simulated annealing method

  8. Accelerated simulated tempering

    Li, Yaohang; Protopopescu, Vladimir A.; Gorin, Andrey

    2004-08-01

    We propose a new stochastic global optimization method by accelerating the simulated tempering scheme with random walks executed on a temperature ladder with various transition step sizes. By suitably choosing the length of the transition steps, the accelerated scheme enables the search process to execute large jumps and escape entrapment in local minima, while retaining the capability to explore local details, whenever warranted. Our simulations confirm the expected improvements and show that the accelerated simulated tempering scheme has a much faster convergence to the target distribution than Geyer and Thompson's simulated tempering algorithm and exhibits accuracy comparable to the simulated annealing method.

  9. Particle accelerator; the Universe machine

    Yurkewicz, Katie

    2008-01-01

    "In summer 2008, scientists will switch on one of the largest machines in the world to search for the smallest of particle. CERN's Large Hadron Collider particle accelerator has the potential to chagne our understanding of the Universe."

  10. Plasma accelerators

    Recently attention has focused on charged particle acceleration in a plasma by a fast, large amplitude, longitudinal electron plasma wave. The plasma beat wave and plasma wakefield accelerators are two efficient ways of producing ultra-high accelerating gradients. Starting with the plasma beat wave accelerator (PBWA) and laser wakefield accelerator (LWFA) schemes and the plasma wakefield accelerator (PWFA) steady progress has been made in theory, simulations and experiments. Computations are presented for the study of LWFA. (author)

  11. Linear Accelerators

    Vretenar, M

    2014-01-01

    The main features of radio-frequency linear accelerators are introduced, reviewing the different types of accelerating structures and presenting the main characteristics aspects of linac beam dynamics.

  12. Memory support for desktop search

    Chen, Yi; Kelly, Liadh; Jones, Gareth J.F.

    2010-01-01

    The user's memory plays a very important role in desktop search. A search query with insufficiently or inaccurately recalled information may make the search dramatically less effective. In this paper, we discuss three approaches to support user’s memory during desktop search. These include extended types of well remembered search options, the use of past search queries and results, and search from similar items. We will also introduce our search system which incorporates these featur...

  13. Studies of accelerated compact toruses

    In an earlier publication we considered acceleration of plasma rings (Compact Torus). Several possible accelerator configurations were suggested and the possibility of focusing the accelerated rings was discussed. In this paper we consider one scheme, acceleration of a ring between coaxial electrodes by a B/sub theta/ field as in a coaxial rail-gun. If the electrodes are conical, a ring accelerated towards the apex of the cone undergoes self-similar compression (focusing) during acceleration. Because the allowable acceleration force, F/sub a/ = kappaU/sub m//R where (kappa -2, the accelerating distance for conical electrodes is considerably shortened over that required for coaxial electrodes. In either case, however, since the accelerating flux can expand as the ring moves, most of the accelerating field energy can be converted into kinetic energy of the ring leading to high efficiency

  14. Fast Structural Search in Phylogenetic Databases

    William H. Piel

    2005-01-01

    Full Text Available As the size of phylogenetic databases grows, the need for efficiently searching these databases arises. Thanks to previous and ongoing research, searching by attribute value and by text has become commonplace in these databases. However, searching by topological or physical structure, especially for large databases and especially for approximate matches, is still an art. We propose structural search techniques that, given a query or pattern tree P and a database of phylogenies D, find trees in D that are sufficiently close to P . The “closeness” is a measure of the topological relationships in P that are found to be the same or similar in a tree D in D. We develop a filtering technique that accelerates searches and present algorithms for rooted and unrooted trees where the trees can be weighted or unweighted. Experimental results on comparing the similarity measure with existing tree metrics and on evaluating the efficiency of the search techniques demonstrate that the proposed approach is promising

  15. Custom Search Engines: Tools & Tips

    Notess, Greg R.

    2008-01-01

    Few have the resources to build a Google or Yahoo! from scratch. Yet anyone can build a search engine based on a subset of the large search engines' databases. Use Google Custom Search Engine or Yahoo! Search Builder or any of the other similar programs to create a vertical search engine targeting sites of interest to users. The basic steps to…

  16. Search for optimal 2D and 3D wave launching configurations for the largest acceleration of charged particles in a magnetized plasma, resonant moments method

    Optimal two-dimensional, three-dimensional wave launching configurations are proposed for enhanced acceleration of charged particles in magnetized plasmas. A primary wave is launched obliquely with respect to the magnetic field and a secondary, low amplitude, wave is launched perpendicularly. The effect of both the launching angle of the primary wave, and the presence of the secondary wave is investigated. Theoretical predictions of the highest performances of the three-dimensional configurations are proposed using a Resonance Moments Method (RMM) based on estimates for the moments of the velocity distribution function calculated inside the resonance layers (RL). They suggest the existence of an optimal angle corresponding to non parallel launching. Direct statistical simulations show that it is possible to rise the mean electron velocity up to the order of magnitude as compared to the primary wave launching alone. It is a quite promising result because the amplitude of the secondary wave is ten times lower than the one of the first wave. The parameters used are related to magnetic plasma fusion experiments in electron cyclotron resonance heating and electron acceleration in planetary ionospheres and magnetospheres. (authors)

  17. Future accelerators (?)

    I describe the future accelerator facilities that are currently foreseen for electroweak scale physics, neutrino physics, and nuclear structure. I will explore the physics justification for these machines, and suggest how the case for future accelerators can be made

  18. Future accelerators (?)

    John Womersley

    2003-08-21

    I describe the future accelerator facilities that are currently foreseen for electroweak scale physics, neutrino physics, and nuclear structure. I will explore the physics justification for these machines, and suggest how the case for future accelerators can be made.

  19. Accelerating Value Creation with Accelerators

    Jonsson, Eythor Ivar

    2015-01-01

    accelerator programs. Microsoft runs accelerators in seven different countries. Accelerators have grown out of the infancy stage and are now an accepted approach to develop new ventures based on cutting-edge technology like the internet of things, mobile technology, big data and virtual reality. It is also......Accelerators can help to accelerate value creation. Accelerators are short-term programs that have the objective of creating innovative and fast growing ventures. They have gained attraction as larger corporations like Microsoft, Barclays bank and Nordea bank have initiated and sponsored...

  20. Perceptual grouping by similarity of surface roughness in haptics: the influence of task difficulty.

    Van Aarsen, V; Overvliet, K E

    2016-08-01

    We investigated grouping by similarity of surface roughness in the context of task difficulty. We hypothesized that grouping yields a larger benefit at higher levels of task complexity, because efficient processing is more helpful when more cognitive resources are needed to execute a task. Participants searched for a patch of a different roughness as compared to the distractors in two strips of similar or dissimilar roughness values. We reasoned that if the distractors could be grouped based on similar roughness values, exploration time would be shorter and fewer errors would occur. To manipulate task complexity, we varied task difficulty (high target saliency equalling low task difficulty), and we varied the fingers used to explore the display (two fingers of one hand being more cognitive demanding than two fingers of opposite hands). We found much better performance in the easy condition as compared to the difficult condition (in both error rates and mean search slopes). Moreover, we found a larger effect for the similarity manipulation in the difficult condition as compared to the easy condition. Within the difficult condition, we found a larger effect for the one-hand condition as compared to the two-hand condition. These results show that haptic search is accelerated by the use of grouping by similarity of surface roughness, especially when the task is relatively complex. We conclude that the effect of perceptual grouping is more prominent when more cognitive resources are needed to perform a task. PMID:27010724

  1. Plasma based accelerators

    Caldwell, Allen [Max-Planck-Institut fuer Physik, Muenchen (Germany)

    2015-05-01

    The concept of laser-induced plasma wakefields as a technique to accelerate charged particles was introduced 35 years ago as a means to go beyond the accelerating gradients possible with metallic cavities supporting radio frequency electromagnetic fields. Significant developments in laser technology have made possible the pulse intensity needed to realize this concept, and rapid progress is now underway in the realization of laser-driven plasma wakefield acceleration. It has also been realized that similar accelerating gradients can be produced by particle beams propagating in plasmas, and experimental programs have also been undertaken to study this possibility. Positive results have been achieved with electron-driven plasma wakefields, and a demonstration experiment with proton-driven wakefields is under construction at CERN. The concepts behind these different schemes and their pros and cons are described, as well as the experimental results achieved. An outlook for future practical uses of plasma based accelerators will also be given.

  2. Fresnel diffraction patterns as accelerating beams

    Zhang, Yiqi; Belić, Milivoj R.; Zheng, Huaibin; Wu, Zhenkun; Li, Yuanyuan; Lu, Keqing; Zhang, Yanpeng

    2013-01-01

    We demonstrate that beams originating from Fresnel diffraction patterns are self-accelerating in free space. In addition to accelerating and self-healing, they also exhibit parabolic deceleration property, which is in stark contrast to other accelerating beams. We find that the trajectory of Fresnel paraxial accelerating beams is similar to that of nonparaxial Weber beams. Decelerating and accelerating regions are separated by a critical propagation distance, at which no acceleration is prese...

  3. Designing reliability into accelerators

    Future accelerators will have to provide a high degree of reliability. Quality must be designed in right from the beginning and must remain a central theme throughout the project. The problem is similar to the problems facing US industry today, and examples of the successful application of quality engineering will be given. Different aspects of an accelerator project will be addressed: Concept, Design, Motivation, Management Techniques, and Fault Diagnosis. The importance of creating and maintaining a coherent team will be stressed

  4. Persistent Homology and Partial Similarity of Shapes

    Di Fabio, Barbara; Landi, Claudia

    2011-01-01

    The ability to perform shape retrieval based not only on full similarity, but also partial similarity is a key property for any content-based search engine. We prove that persistence diagrams can reveal a partial similarity between two shapes by showing a common subset of points. This can be explained using the Mayer-Vietoris formulas that we develop for ordinary, relative and extended persistent homology. An experiment outlines the potential of persistence diagrams as shape descriptors in re...

  5. Are Defect Profile Similarity Criteria Different Than Velocity Profile Similarity Criteria for the Turbulent Boundary Layer?

    Weyburne, David

    2015-01-01

    The use of the defect profile instead of the experimentally observed velocity profile for the search for similarity parameters has become firmly imbedded in the turbulent boundary layer literature. However, a search of the literature reveals that there are no theoretical reasons for this defect profile preference over the more traditional velocity profile. In the report herein, we use the flow governing equation approach to develop similarity criteria for the two profiles. Results show that t...

  6. The baryonic self similarity of dark matter

    Alard, C., E-mail: alard@iap.fr [Institut d' Astrophysique de Paris, 98bis boulevard Arago, F-75014 Paris (France)

    2014-06-20

    The cosmological simulations indicates that dark matter halos have specific self-similar properties. However, the halo similarity is affected by the baryonic feedback. By using momentum-driven winds as a model to represent the baryon feedback, an equilibrium condition is derived which directly implies the emergence of a new type of similarity. The new self-similar solution has constant acceleration at a reference radius for both dark matter and baryons. This model receives strong support from the observations of galaxies. The new self-similar properties imply that the total acceleration at larger distances is scale-free, the transition between the dark matter and baryons dominated regime occurs at a constant acceleration, and the maximum amplitude of the velocity curve at larger distances is proportional to M {sup 1/4}. These results demonstrate that this self-similar model is consistent with the basics of modified Newtonian dynamics (MOND) phenomenology. In agreement with the observations, the coincidence between the self-similar model and MOND breaks at the scale of clusters of galaxies. Some numerical experiments show that the behavior of the density near the origin is closely approximated by a Einasto profile.

  7. Finding Protein and Nucleotide Similarities with FASTA.

    Pearson, William R

    2016-01-01

    The FASTA programs provide a comprehensive set of rapid similarity searching tools (fasta36, fastx36, tfastx36, fasty36, tfasty36), similar to those provided by the BLAST package, as well as programs for slower, optimal, local, and global similarity searches (ssearch36, ggsearch36), and for searching with short peptides and oligonucleotides (fasts36, fastm36). The FASTA programs use an empirical strategy for estimating statistical significance that accommodates a range of similarity scoring matrices and gap penalties, improving alignment boundary accuracy and search sensitivity. The FASTA programs can produce "BLAST-like" alignment and tabular output, for ease of integration into existing analysis pipelines, and can search small, representative databases, and then report results for a larger set of sequences, using links from the smaller dataset. The FASTA programs work with a wide variety of database formats, including mySQL and postgreSQL databases. The programs also provide a strategy for integrating domain and active site annotations into alignments and highlighting the mutational state of functionally critical residues. These protocols describe how to use the FASTA programs to characterize protein and DNA sequences, using protein:protein, protein:DNA, and DNA:DNA comparisons. © 2016 by John Wiley & Sons, Inc. PMID:27010337

  8. Clustering by Pattern Similarity

    Hai-xun Wang; Jian Pei

    2008-01-01

    The task of clustering is to identify classes of similar objects among a set of objects. The definition of similarity varies from one clustering model to another. However, in most of these models the concept of similarity is often based on such metrics as Manhattan distance, Euclidean distance or other Lp distances. In other words, similar objects must have close values in at least a set of dimensions. In this paper, we explore a more general type of similarity. Under the pCluster model we proposed, two objects are similar if they exhibit a coherent pattern on a subset of dimensions. The new similarity concept models a wide range of applications. For instance, in DNA microarray analysis, the expression levels of two genes may rise and fall synchronously in response to a set of environmental stimuli. Although the magnitude of their expression levels may not be close, the patterns they exhibit can be very much alike. Discovery of such clusters of genes is essential in revealing significant connections in gene regulatory networks. E-commerce applications, such as collaborative filtering, can also benefit from the new model, because it is able to capture not only the closeness of values of certain leading indicators but also the closeness of (purchasing, browsing, etc.) patterns exhibited by the customers. In addition to the novel similarity model, this paper also introduces an effective and efficient algorithm to detect such clusters, and we perform tests on several real and synthetic data sets to show its performance.

  9. Laser accelerator

    Vigil, Ricardo

    2014-01-01

    Approved for public release; distribution is unlimited In 1979,W. B. Colson and S. K. Ride proposed a new kind of electron accelerator using a uniform magnetic field in combination with a circularly-polarized laser field. A key concept is to couple the oscillating electric field to the electron’s motion so that acceleration is sustained. This dissertation investigates the performance of the proposed laser accelerator using modern high powered lasers and mag-netic fields that are significan...

  10. The semantic similarity ensemble

    Andrea Ballatore

    2013-12-01

    Full Text Available Computational measures of semantic similarity between geographic terms provide valuable support across geographic information retrieval, data mining, and information integration. To date, a wide variety of approaches to geo-semantic similarity have been devised. A judgment of similarity is not intrinsically right or wrong, but obtains a certain degree of cognitive plausibility, depending on how closely it mimics human behavior. Thus selecting the most appropriate measure for a specific task is a significant challenge. To address this issue, we make an analogy between computational similarity measures and soliciting domain expert opinions, which incorporate a subjective set of beliefs, perceptions, hypotheses, and epistemic biases. Following this analogy, we define the semantic similarity ensemble (SSE as a composition of different similarity measures, acting as a panel of experts having to reach a decision on the semantic similarity of a set of geographic terms. The approach is evaluated in comparison to human judgments, and results indicate that an SSE performs better than the average of its parts. Although the best member tends to outperform the ensemble, all ensembles outperform the average performance of each ensemble's member. Hence, in contexts where the best measure is unknown, the ensemble provides a more cognitively plausible approach.

  11. Gender similarities and differences.

    Hyde, Janet Shibley

    2014-01-01

    Whether men and women are fundamentally different or similar has been debated for more than a century. This review summarizes major theories designed to explain gender differences: evolutionary theories, cognitive social learning theory, sociocultural theory, and expectancy-value theory. The gender similarities hypothesis raises the possibility of theorizing gender similarities. Statistical methods for the analysis of gender differences and similarities are reviewed, including effect sizes, meta-analysis, taxometric analysis, and equivalence testing. Then, relying mainly on evidence from meta-analyses, gender differences are reviewed in cognitive performance (e.g., math performance), personality and social behaviors (e.g., temperament, emotions, aggression, and leadership), and psychological well-being. The evidence on gender differences in variance is summarized. The final sections explore applications of intersectionality and directions for future research. PMID:23808917

  12. Cluster Tree Based Hybrid Document Similarity Measure

    M. Varshana Devi

    2015-10-01

    Full Text Available similarity measure is established to measure the hybrid similarity. In cluster tree, the hybrid similarity measure can be calculated for the random data even it may not be the co-occurred and generate different views. Different views of tree can be combined and choose the one which is significant in cost. A method is proposed to combine the multiple views. Multiple views are represented by different distance measures into a single cluster. Comparing the cluster tree based hybrid similarity with the traditional statistical methods it gives the better feasibility for intelligent based search. It helps in improving the dimensionality reduction and semantic analysis.

  13. LIBO accelerates

    2002-01-01

    The prototype module of LIBO, a linear accelerator project designed for cancer therapy, has passed its first proton-beam acceleration test. In parallel a new version - LIBO-30 - is being developed, which promises to open up even more interesting avenues.

  14. Induction accelerators

    Takayama, Ken

    2011-01-01

    A broad class of accelerators rests on the induction principle whereby the accelerating electrical fields are generated by time-varying magnetic fluxes. Particularly suitable for the transport of bright and high-intensity beams of electrons, protons or heavy ions in any geometry (linear or circular) the research and development of induction accelerators is a thriving subfield of accelerator physics. This text is the first comprehensive account of both the fundamentals and the state of the art about the modern conceptual design and implementation of such devices. Accordingly, the first part of the book is devoted to the essential features of and key technologies used for induction accelerators at a level suitable for postgraduate students and newcomers to the field. Subsequent chapters deal with more specialized and advanced topics.

  15. Acceleration and improvement of dental implants’ osseointegration. Current perspective

    Gregory VENETIS; Dimitris TATSIS; Florentia STYLIANOU; Charalampos SYMEONIDIS

    2014-01-01

    The possibility to accelerate osseointegration and/or to improve bone quality around an implant is the subject of the present literature review. The following key words were searched on Pubmed: ac-celerate, improvement, osseointegration. The publication date span was set from 2009 to 2013. Combinations of the search terms retrieved the following results: a) ac-celerate and osseointegration: 78 papers; b) improve-ment and sseointegration: 206 papers. A supplementary search on the surgical t...

  16. Constructive Similarity of Soils

    Koudelka, Petr

    Singapore : Design, CRC a iTEK CMS Web solutions, 2012 - (Phoon, K.; Beer, M.; Quek, S.; Pang, S.), s. 206-211 ISBN 978-981-07-2218-0. [APS on Structural Reliability and Its Application – Sustainable Civil Infrastructures /5./. Singapore (SG), 23.05.2012-25.05.2012] Grant ostatní: GA ČR(CZ) GAP105/11/1160 Institutional support: RVO:68378297 Keywords : model similarity * database of soil properties * soil similarity characteristic * statistical analysis * ultimate limit states Subject RIV: JM - Building Engineering

  17. Music Retrieval based on Melodic Similarity

    Typke, R.

    2007-01-01

    This thesis introduces a method for measuring melodic similarity for notated music such as MIDI files. This music search algorithm views music as sets of notes that are represented as weighted points in the two-dimensional space of time and pitch. Two point sets can be compared by calculating how mu

  18. Similarity of molecular shape.

    Meyer, A Y; Richards, W G

    1991-10-01

    The similarity of one molecule to another has usually been defined in terms of electron densities or electrostatic potentials or fields. Here it is expressed as a function of the molecular shape. Formulations of similarity (S) reduce to very simple forms, thus rendering the computerised calculation straightforward and fast. 'Elements of similarity' are identified, in the same spirit as 'elements of chirality', except that the former are understood to be variable rather than present-or-absent. Methods are presented which bypass the time-consuming mathematical optimisation of the relative orientation of the molecules. Numerical results are presented and examined, with emphasis on the similarity of isomers. At the extreme, enantiomeric pairs are considered, where it is the dissimilarity (D = 1 - S) that is of consequence. We argue that chiral molecules can be graded by dissimilarity, and show that D is the shape-analog of the 'chirality coefficient', with the simple form of the former opening up numerical access to the latter. PMID:1770379

  19. The Qualitative Similarity Hypothesis

    Paul, Peter V.; Lee, Chongmin

    2010-01-01

    Evidence is presented for the qualitative similarity hypothesis (QSH) with respect to children and adolescents who are d/Deaf or hard of hearing. The primary focus is on the development of English language and literacy skills, and some information is provided on the acquisition of English as a second language. The QSH is briefly discussed within…

  20. Limiting Similarity Revisited

    Szabo, P; Meszena, G.

    2005-01-01

    We reinvestigate the validity of the limiting similarity principle via numerical simulations of the Lotka-Volterra model. A Gaussian competition kernel is employed to describe decreasing competition with increasing difference in a one-dimensional phenotype variable. The simulations are initiated by a large number of species, evenly distributed along the phenotype axis. Exceptionally, the Gaussian carrying capacity supports coexistence of all species, initially present. In case of any other, d...

  1. Accelerating execution of the integrated TIGER series Monte Carlo radiation transport codes

    Execution of the integrated TIGER series (ITS) of coupled electron/photon Monte Carlo radiation transport codes has been accelerated by modifying the FORTRAN source code for more efficient computation. Each member code of ITS was benchmarked and profiled with a specific test case that directed the acceleration effort toward the most computationally intensive subroutines. Techniques for accelerating these subroutines included replacing linear search algorithms with binary versions, replacing the pseudo-random number generator, reducing program memory allocation, and proofing the input files for geometrical redundancies. All techniques produced identical or statistically similar results to the original code. Final benchmark timing of the accelerated code resulted in speed-up factors of 2.00 for TIGER (the one-dimensional slab geometry code), 1.74 for CYLTRAN (the two-dimensional cylindrical geometry code), and 1.90 for ACCEPT (the arbitrary three-dimensional geometry code)

  2. The Application of Similar Image Retrieval in Electronic Commerce

    YuPing Hu

    2014-01-01

    Full Text Available Traditional online shopping platform (OSP, which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers’ experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system.

  3. The application of similar image retrieval in electronic commerce.

    Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

    2014-01-01

    Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system. PMID:24883411

  4. A new approach for finding semantic similar scientific articles

    Masumeh Islami Nasab; Reza Javidan

    2015-01-01

    Calculating article similarities enables users to find similar articles and documents in a collection of articles. Two similar documents are extremely helpful for text applications such as document-to-document similarity search, plagiarism checker, text mining for repetition, and text filtering. This paper proposes a new method for calculating the semantic similarities of articles. WordNet is used to find word semantic associations. The proposed technique first compares the similarity of each...

  5. Exceptional Ground Accelerations and Velocities Caused by Earthquakes

    Anderson, John

    2008-01-17

    This project aims to understand the characteristics of the free-field strong-motion records that have yielded the 100 largest peak accelerations and the 100 largest peak velocities recorded to date. The peak is defined as the maximum magnitude of the acceleration or velocity vector during the strong shaking. This compilation includes 35 records with peak acceleration greater than gravity, and 41 records with peak velocities greater than 100 cm/s. The results represent an estimated 150,000 instrument-years of strong-motion recordings. The mean horizontal acceleration or velocity, as used for the NGA ground motion models, is typically 0.76 times the magnitude of this vector peak. Accelerations in the top 100 come from earthquakes as small as magnitude 5, while velocities in the top 100 all come from earthquakes with magnitude 6 or larger. Records are dominated by crustal earthquakes with thrust, oblique-thrust, or strike-slip mechanisms. Normal faulting mechanisms in crustal earthquakes constitute under 5% of the records in the databases searched, and an even smaller percentage of the exceptional records. All NEHRP site categories have contributed exceptional records, in proportions similar to the extent that they are represented in the larger database.

  6. Tandem accelerators

    After the installation of Ti-acceleration tubes and substantial modifications and additions to the EN tandem accelerator the performance of the machine has stabilized. The voltage behaviour of the tubes obviously improves as conditioning times necessary to run up to 6 MV decrease. A gridded lens has been added at the entrance of the first acceleration tube, and a second foil stripper is now installed in the short dead section between the high-energy tubes. The MP tandem also has been running stably during most of the year. However, beam instabilities originating from the last tube section and wear problems at the low-energy set of pelletron-chains caused some loss of beam time. During the fall, one set of pelletron charging chains has to be replaced after 49,000 hours of operation. In the course of the year, the MP and the EN tandem accelerators finished their 100,000th and 150,000th hours of operations, respectively. Preparations for the installation of the 3 MV negative heavy ion injector for the MP are progressing steadily. External beam transport, terminal ion optics, and data acquisition and control systems are to a major extent completed; the integration of the terminal power supplies has started. After the final assembly of the accelerator column structure, first voltage runs can be performed. (orig.)

  7. The qualitative similarity hypothesis.

    Paul, Peter V; Lee, Chongmin

    2010-01-01

    Evidence is presented for the qualitative similarity hypothesis (QSH) with respect to children and adolescents who are d/Deaf or hard of hearing. The primary focus is on the development of English language and literacy skills, and some information is provided on the acquisition of English as a second language. The QSH is briefly discussed within the purview of two groups of cognitive models: those that emphasize the cognitive development of individuals and those that pertain to disciplinary or knowledge structures. It is argued that the QSH has scientific merit with implications for classroom instruction. Future research should examine the validity of the QSH in other disciplines such as mathematics and science and should include perspectives from social as well as cognitive models. PMID:20415280

  8. Self Similar Optical Fiber

    Lai, Zheng-Xuan

    This research proposes Self Similar optical fiber (SSF) as a new type of optical fiber. It has a special core that consists of self similar structure. Such a structure is obtained by following the formula for generating iterated function systems (IFS) in Fractal Theory. The resulted SSF can be viewed as a true fractal object in optical fibers. In addition, the method of fabricating SSF makes it possible to generate desired structures exponentially in numbers, whereas it also allows lower scale units in the structure to be reduced in size exponentially. The invention of SSF is expected to greatly ease the production of optical fiber when a large number of small hollow structures are needed in the core of the optical fiber. This dissertation will analyze the core structure of SSF based on fractal theory. Possible properties from the structural characteristics and the corresponding applications are explained. Four SSF samples were obtained through actual fabrication in a laboratory environment. Different from traditional conductive heating fabrication system, I used an in-house designed furnace that incorporated a radiation heating method, and was equipped with automated temperature control system. The obtained samples were examined through spectrum tests. Results from the tests showed that SSF does have the optical property of delivering light in a certain wavelength range. However, SSF as a new type of optical fiber requires a systematic research to find out the theory that explains its structure and the associated optical properties. The fabrication and quality of SSF also needs to be improved for product deployment. As a start of this extensive research, this dissertation work opens the door to a very promising new area in optical fiber research.

  9. Concept Search: Semantics Enabled Information Retrieval

    Giunchiglia, Fausto; Kharkevich, Uladzimir; Zaihrayeu, Ilya

    2010-01-01

    In this paper we present a novel approach, called Concept Search, which extends syntactic search, i.e., search based on the computation of string similarity between words, with semantic search, i.e., search based on the computation of semantic relations between concepts. The key idea of Concept Search is to operate on complex concepts and to maximally exploit the semantic information available, reducing to syntactic search only when necessary, i.e., when no semantic information is available. ...

  10. Particle acceleration

    Vlahos, L.; Machado, M. E.; Ramaty, R.; Murphy, R. J.; Alissandrakis, C.; Bai, T.; Batchelor, D.; Benz, A. O.; Chupp, E.; Ellison, D.

    1986-01-01

    Data is compiled from Solar Maximum Mission and Hinothori satellites, particle detectors in several satellites, ground based instruments, and balloon flights in order to answer fundamental questions relating to: (1) the requirements for the coronal magnetic field structure in the vicinity of the energization source; (2) the height (above the photosphere) of the energization source; (3) the time of energization; (4) transistion between coronal heating and flares; (5) evidence for purely thermal, purely nonthermal and hybrid type flares; (6) the time characteristics of the energization source; (7) whether every flare accelerates protons; (8) the location of the interaction site of the ions and relativistic electrons; (9) the energy spectra for ions and relativistic electrons; (10) the relationship between particles at the Sun and interplanetary space; (11) evidence for more than one acceleration mechanism; (12) whether there is single mechanism that will accelerate particles to all energies and also heat the plasma; and (13) how fast the existing mechanisms accelerate electrons up to several MeV and ions to 1 GeV.

  11. Accelerator design

    The feasibility of constructing a TeV region electron-positron linear collider in Japan is discussed. The design target of the collider is given as follows: Energy, 1 TeV + 1 TeV; luminosity, 1032-1033/cm2/s; total length, 25km; electric power, 250MW; energy dispersion, 1%-10%; the start of the first experiment, early 1990s. For realizing the above target, the following research and developmental works are necessary. (a) Development of an acceleration tube with short filling time and high shunt resistance. (b) Short pulse microwave source with high peak power. (c) High current, single bunch linac. (d) Beam dynamics. As for the acceleration tube, some possibility is considered: For example, the use of DAW (Disk and Washer) which is being developed for TRISTAN as a traveling-wave tube; and the Jungle Gym-type acceleration tube. As a promising candidate for the microwave source, the Lasertron has been studied. The total cost of the collider construction is estimated to be about 310 billion yen, of which 120 billion yen is for the tunnel and buildings, and 190 billion yen for the accelerator facilities. The operation cost is estimated to be about 3 billion yen per month. (Aoki, K.)

  12. Accelerator operations

    This section is concerned with the operation of both the tandem-linac system and the Dynamitron, two accelerators that are used for entirely different research. Developmental activities associated with the tandem and the Dynamitron are also treated here, but developmental activities associated with the superconducting linac are covered separately because this work is a program of technology development in its own right

  13. Advanced accelerators

    This report discusses the suitability of four novel particle acceleration technologies for multi-TeV particle physics machines: laser driven linear accelerators (linac), plasma beat-wave devices, plasma wakefield devices, and switched power and cavity wakefield linacs. The report begins with the derivation of beam parameters practical for multi-TeV devices. Electromagnetic field breakdown of materials is reviewed. The two-beam accelerator scheme for using a free electron laser as the driver is discussed. The options recommended and the conclusions reached reflect the importance of cost. We recommend that more effort be invested in achieving a self-consistent range of TeV accelerator design parameters. Beat-wave devices have promise for 1-100 GeV applications and, while not directly scalable to TeV designs, the current generation of ideas are encouraging for the TeV regime. In particular, surfatrons, finite-angle optical mixing devices, plasma grating accelerator, and the Raman forward cascade schemes all deserve more complete analysis. The exploitation of standard linac geometry operated in an unconventional mode is in a phase of rapid evolution. While conceptual projects abound, there are no complete designs. We recommend that a fraction of sponsored research be devoted to this approach. Wakefield devices offer a great deal of potential; trades among their benefits and constraints are derived and discussed herein. The study of field limitation processes has received inadequate attention; this limits experiment designers. The costs of future experiments are such that investment in understanding these processes is prudent. 34 refs., 12 figs., 3 tabs

  14. CAS CERN Accelerator School. Measurement and alignment of accelerator and detector magnets. Proceedings

    These proceedings present the lectures given at the eleventh specialised course organised by the CERN Accelerator School (CAS), the topic this time being 'Measurement and Alignment of Accelerator and Detector Magnets'. A similar course was already presented at Montreux, Switzerland in 1992 and its proceedings published as CERN 92-05. However recent progress in the field, especially in the use of superconducting magnets, has been so rapid that a revised course had become imperative. The lectures start with basic magnet theory and the motivation for magnet measurements followed by a review of superconducting magnets and their field dynamics. After a review of measurement methods, the details of search and harmonic coils, magnetic resonance techniques and Hall generators are given followed by methods to minimise errors in mechanical equipment, series production and detector magnet measurements. Turning to magnet metrology and alignment, first data quality control is explained followed by the setting of reference targets, and the alignment methods for accelerators and experiments including alignment by feedback. Finally seminars are presented on the biological effects of magnetic fields and on superconducting magnet fabrication and quality control. (orig.)

  15. Similarity search and data mining techniques for advanced database systems.

    Pryakhin, Alexey

    2006-01-01

    Modern automated methods for measurement, collection, and analysis of data in industry and science are providing more and more data with drastically increasing structure complexity. On the one hand, this growing complexity is justified by the need for a richer and more precise description of real-world objects, on the other hand it is justified by the rapid progress in measurement and analysis techniques that allow the user a versatile exploration of objects. In order to manage the huge volum...

  16. Time Searching for Similar Binary Vectors in Associative Memory

    Frolov, A. A.; Húsek, Dušan; Rachkovskij, D.

    2006-01-01

    Roč. 42, č. 5 (2006), s. 615-623. ISSN 1060-0396 R&D Projects: GA MŠk(CZ) 1M0567 Institutional research plan: CEZ:AV0Z10300504 Keywords : associative memory * neural network * Hopfield network * binary vector * indexing * hashing Subject RIV: BB - Applied Statistics, Operational Research

  17. Fresnel diffraction patterns as accelerating beams

    Zhang, Yiqi; Zheng, Huaibin; Wu, Zhenkun; Li, Yuanyuan; Lu, Keqing; Zhang, Yanpeng

    2013-01-01

    We demonstrate that beams originating from Fresnel diffraction patterns are self-accelerating in free space. In addition to accelerating and self-healing, they also exhibit parabolic deceleration property, which is in stark contrast to other accelerating beams. We find that the trajectory of Fresnel paraxial accelerating beams is similar to that of nonparaxial Weber beams. Decelerating and accelerating regions are separated by a critical propagation distance, at which no acceleration is present. During deceleration, the Fresnel diffraction beams undergo self-smoothing, in which oscillations of the diffracted waves gradually focus and smooth out at the critical distance.

  18. Uniformly Accelerated Observer in Moyal Spacetime

    Acharyya, Nirmalendu; Vaidya, Sachindeo

    2010-01-01

    In Minkowski space, an accelerated reference frame may be defined as one that is related to an inertial frame by a sequence of instantaneous Lorentz transformations. Such an accelerated observer sees a causal horizon, and the quantum vacuum of the inertial observer appears thermal to the accelerated observer, also known as the Unruh effect. We argue that an accelerating frame may be similarly defined (i.e. as a sequence of instantaneous Lorentz transformations) in noncommutative Moyal spaceti...

  19. Efficient Similarity Retrieval in Music Databases

    Ruxanda, Maria Magdalena; Jensen, Christian Søndergaard

    2006-01-01

    Audio music is increasingly becoming available in digital form, and the digital music collections of individuals continue to grow. Addressing the need for effective means of retrieving music from such collections, this paper proposes new techniques for content-based similarity search. Each music...... object is modeled as a time sequence of high-dimensional feature vectors, and dynamic time warping (DTW) is used as the similarity measure. To accomplish this, the paper extends techniques for time-series-length reduction and lower bounding of DTW distance to the multi-dimensional case. Further, the...

  20. Professional Microsoft search fast search, Sharepoint search, and search server

    Bennett, Mark; Kehoe, Miles; Voskresenskaya, Natalya

    2010-01-01

    Use Microsoft's latest search-based technology-FAST search-to plan, customize, and deploy your search solutionFAST is Microsoft's latest intelligent search-based technology that boasts robustness and an ability to integrate business intelligence with Search. This in-depth guide provides you with advanced coverage on FAST search and shows you how to use it to plan, customize, and deploy your search solution, with an emphasis on SharePoint 2010 and Internet-based search solutions.With a particular appeal for anyone responsible for implementing and managing enterprise search, this book presents t

  1. Integrated Semantic Similarity Model Based on Ontology

    LIU Ya-Jun; ZHAO Yun

    2004-01-01

    To solve the problem of the inadequacy of semantic processing in the intelligent question answering system, an integrated semantic similarity model which calculates the semantic similarity using the geometric distance and information content is presented in this paper.With the help of interrelationship between concepts, the information content of concepts and the strength of the edges in the ontology network, we can calculate the semantic similarity between two concepts and provide information for the further calculation of the semantic similarity between user's question and answers in knowlegdge base.The results of the experiments on the prototype have shown that the semantic problem in natural language processing can also be solved with the help of the knowledge and the abundant semantic information in ontology.More than 90% accuracy with less than 50 ms average searching time in the intelligent question answering prototype system based on ontology has been reached.The result is very satisfied.

  2. MUON ACCELERATION

    BERG,S.J.

    2003-11-18

    One of the major motivations driving recent interest in FFAGs is their use for the cost-effective acceleration of muons. This paper summarizes the progress in this area that was achieved leading up to and at the FFAG workshop at KEK from July 7-12, 2003. Much of the relevant background and references are also given here, to give a context to the progress we have made.

  3. KEKB accelerator

    KEKB, the B-Factory at High Energy Accelerator Research Organization (KEK) recently achieved the luminosity of 1 x 1034 cm-2s-1. This luminosity is two orders higher than the world's level at 1990 when the design of KEKB started. This unprecedented result was made possible by KEKB's innovative design and technology in three aspects - beam focusing optics, high current storage, and beam - beam interaction. Now KEKB is leading the luminosity frontier of the colliders in the world. (author)

  4. Accelerating networks

    Evolving out-of-equilibrium networks have been under intense scrutiny recently. In many real-world settings the number of links added per new node is not constant but depends on the time at which the node is introduced in the system. This simple idea gives rise to the concept of accelerating networks, for which we review an existing definition and-after finding it somewhat constrictive-offer a new definition. The new definition provided here views network acceleration as a time dependent property of a given system as opposed to being a property of the specific algorithm applied to grow the network. The definition also covers both unweighted and weighted networks. As time-stamped network data becomes increasingly available, the proposed measures may be easily applied to such empirical datasets. As a simple case study we apply the concepts to study the evolution of three different instances of Wikipedia, namely, those in English, German, and Japanese, and find that the networks undergo different acceleration regimes in their evolution

  5. One Shot Detection with Laplacian Object and Fast Matrix Cosine Similarity.

    Biswas, Sujoy Kumar; Milanfar, Peyman

    2016-03-01

    One shot, generic object detection involves searching for a single query object in a larger target image. Relevant approaches have benefited from features that typically model the local similarity patterns. In this paper, we combine local similarity (encoded by local descriptors) with a global context (i.e., a graph structure) of pairwise affinities among the local descriptors, embedding the query descriptors into a low dimensional but discriminatory subspace. Unlike principal components that preserve global structure of feature space, we actually seek a linear approximation to the Laplacian eigenmap that permits us a locality preserving embedding of high dimensional region descriptors. Our second contribution is an accelerated but exact computation of matrix cosine similarity as the decision rule for detection, obviating the computationally expensive sliding window search. We leverage the power of Fourier transform combined with integral image to achieve superior runtime efficiency that allows us to test multiple hypotheses (for pose estimation) within a reasonably short time. Our approach to one shot detection is training-free, and experiments on the standard data sets confirm the efficacy of our model. Besides, low computation cost of the proposed (codebook-free) object detector facilitates rather straightforward query detection in large data sets including movie videos. PMID:27046497

  6. Search Cloud

    ... https://www.nlm.nih.gov/medlineplus/cloud.html Search Cloud To use the sharing features on this page, please enable JavaScript. Share the MedlinePlus search cloud with your users by embedding our search ...

  7. Search Tips

    ... do not need to use AND because the search engine automatically finds resources containing all of your search ... Use as a wildcard when you want the search engine to fill in the blank for you; you ...

  8. Search Cloud

    ... this page: https://medlineplus.gov/cloud.html Search Cloud To use the sharing features on this page, ... Top 110 zoster vaccine Share the MedlinePlus search cloud with your users by embedding our search cloud ...

  9. Accelerators and the Accelerator Community

    Malamud, Ernest; Sessler, Andrew

    2008-06-01

    In this paper, standing back--looking from afar--and adopting a historical perspective, the field of accelerator science is examined. How it grew, what are the forces that made it what it is, where it is now, and what it is likely to be in the future are the subjects explored. Clearly, a great deal of personal opinion is invoked in this process.

  10. Stochastic modeling of Lagrangian accelerations

    Reynolds, Andy

    2002-11-01

    It is shown how Sawford's second-order Lagrangian stochastic model (Phys. Fluids A 3, 1577-1586, 1991) for fluid-particle accelerations can be combined with a model for the evolution of the dissipation rate (Pope and Chen, Phys. Fluids A 2, 1437-1449, 1990) to produce a Lagrangian stochastic model that is consistent with both the measured distribution of Lagrangian accelerations (La Porta et al., Nature 409, 1017-1019, 2001) and Kolmogorov's similarity theory. The later condition is found not to be satisfied when a constant dissipation rate is employed and consistency with prescribed acceleration statistics is enforced through fulfilment of a well-mixed condition.

  11. accelerating cavity

    On the inside of the cavitytThere is a layer of niobium. Operating at 4.2 degrees above absolute zero, the niobium is superconducting and carries an accelerating field of 6 million volts per metre with negligible losses. Each cavity has a surface of 6 m2. The niobium layer is only 1.2 microns thick, ten times thinner than a hair. Such a large area had never been coated to such a high accuracy. A speck of dust could ruin the performance of the whole cavity so the work had to be done in an extremely clean environment.

  12. Notions of similarity for computational biology models

    Waltemath, Dagmar

    2016-03-21

    Computational models used in biology are rapidly increasing in complexity, size, and numbers. To build such large models, researchers need to rely on software tools for model retrieval, model combination, and version control. These tools need to be able to quantify the differences and similarities between computational models. However, depending on the specific application, the notion of similarity may greatly vary. A general notion of model similarity, applicable to various types of models, is still missing. Here, we introduce a general notion of quantitative model similarities, survey the use of existing model comparison methods in model building and management, and discuss potential applications of model comparison. To frame model comparison as a general problem, we describe a theoretical approach to defining and computing similarities based on different model aspects. Potentially relevant aspects of a model comprise its references to biological entities, network structure, mathematical equations and parameters, and dynamic behaviour. Future similarity measures could combine these model aspects in flexible, problem-specific ways in order to mimic users\\' intuition about model similarity, and to support complex model searches in databases.

  13. SProt: sphere-based protein structure similarity algorithm

    2011-01-01

    Background Similarity search in protein databases is one of the most essential issues in computational proteomics. With the growing number of experimentally resolved protein structures, the focus shifted from sequences to structures. The area of structure similarity forms a big challenge since even no standard definition of optimal structure similarity exists in the field. Results We propose a protein structure similarity measure called SProt. SProt concentrates on high-quality modeling of lo...

  14. Electron Accelerator Facilities

    Lecture presents main aspects of progress in development of industrial accelerators: adaptation of accelerators primary built for scientific experiments, electron energy and beam power increase in certain accelerator constructions, computer control system managing accelerator start-up, routine operation and technological process, maintenance (diagnostics), accelerator technology perfection (electrical efficiency, operation cost), compact and more efficient accelerator constructions, reliability improvement according to industrial standards, accelerators for MW power levels and accelerators tailored for specific use

  15. Search Patterns

    Morville, Peter

    2010-01-01

    What people are saying about Search Patterns "Search Patterns is a delight to read -- very thoughtful and thought provoking. It's the most comprehensive survey of designing effective search experiences I've seen." --Irene Au, Director of User Experience, Google "I love this book! Thanks to Peter and Jeffery, I now know that search (yes, boring old yucky who cares search) is one of the coolest ways around of looking at the world." --Dan Roam, author, The Back of the Napkin (Portfolio Hardcover) "Search Patterns is a playful guide to the practical concerns of search interface design. It cont

  16. Accelerator system and method of accelerating particles

    Wirz, Richard E. (Inventor)

    2010-01-01

    An accelerator system and method that utilize dust as the primary mass flux for generating thrust are provided. The accelerator system can include an accelerator capable of operating in a self-neutralizing mode and having a discharge chamber and at least one ionizer capable of charging dust particles. The system can also include a dust particle feeder that is capable of introducing the dust particles into the accelerator. By applying a pulsed positive and negative charge voltage to the accelerator, the charged dust particles can be accelerated thereby generating thrust and neutralizing the accelerator system.

  17. Searches for new macroscopic forces

    The search for new interactions and their associated bosons is a central theme in modern physics. Such searches are particularly topical today, when there is a consensus that the Standard Model cannot be complete, and that new interactions and their mediating particles are required. However, because of the wide variety of theoretical ideas for overcoming the perceived difficulties of the Standard Model, there is no consensus on the expected properties of mediating particles. One normally supposes that the bosons mediating these new interactions have not been observed because they are too massive to have been produced by existing accelerators. Therefore particle searches are usually conducted at the highest energy accelerators. However, it has recently been recognized that there is another quite different and largely unexplored window on possible new physics, namely the search for new bosons with masses so low that they would generate a macroscopic force. This paper covers recent theoretical and experimental work that addresses this possibility

  18. Relativistic mergers of black hole binaries have large, similar masses, low spins and are circular

    Amaro-Seoane, Pau; Chen, Xian

    2016-05-01

    Gravitational waves are a prediction of general relativity, and with ground-based detectors now running in their advanced configuration, we will soon be able to measure them directly for the first time. Binaries of stellar-mass black holes are among the most interesting sources for these detectors. Unfortunately, the many different parameters associated with the problem make it difficult to promptly produce a large set of waveforms for the search in the data stream. To reduce the number of templates to develop, one must restrict some of the physical parameters to a certain range of values predicted by either (electromagnetic) observations or theoretical modelling. In this work, we show that `hyperstellar' black holes (HSBs) with masses 30 ≲ MBH/M⊙ ≲ 100, i.e black holes significantly larger than the nominal 10 M⊙, will have an associated low value for the spin, i.e. a similar masses. We also address the distribution of the eccentricities of HSB binaries in dense stellar systems using a large suite of three-body scattering experiments that include binary-single interactions and long-lived hierarchical systems with a highly accurate integrator, including relativistic corrections up to O(1/c^5). We find that most sources in the detector band will have nearly zero eccentricities. This correlation between large, similar masses, low spin and low eccentricity will help to accelerate the searches for gravitational-wave signals.

  19. Application of linear induction accelerator for environmental applications

    Growing interest in the usage of power beams in industrial applications governs the design and development of various kinds of latest accelerators of high voltage, high energy, low current or high voltage high current but low average power accelerators. Conventional accelerators can be of electrostatic accelerators (Van-de-Graaff), high voltage multiplier column based accelerators (Cockcroft Walton/dynamatron type) or Microwave frequency based accelerators (R.F.LINAC) and Pulsed accelerators (Marx generator and PFL type). Linear Induction Accelerator (LIA) is linear in voltage acceleration configuration and beam gets coupled to the input pulse power by induction. It is compact and mobile compared to other accelerators of similar power regime. A unique feature of the induction accelerator is that peak voltage appears only at the output. This paper illustrates the principle and applications of linear Induction accelerator, global scenario and BARC status in this thrust area. (author)

  20. P2P Concept Search: Some Preliminary Results

    Giunchiglia, Fausto; Kharkevich, Uladzimir; Noori, S.R.H

    2009-01-01

    Concept Search extends syntactic search, i.e., search based on the computation of string similarity between words, with semantic search, i.e., search based on the computation of semantic relations between complex concepts. It allows us to deal with ambiguity of natural language. P2P Concept Search extends Concept Search by allowing distributed semantic search over structured P2P network. The key idea is to exploit distributed, rather than centralized, background knowledge and indices.

  1. Accelerating the Response of Query in Semantic Web

    Nooshin Azimi

    2014-07-01

    Full Text Available Today, XML has become one of the important formats of saving and exchanging data. XML structure flexibility enhances its use, and the content of XML documents is increasing constantly. As a result, since file management system is not able to manage such content of data, managing XML documents requires a comprehensive management system. With the striking growth of such databases, the necessity of accelerating the implementing operation of queries is felt. In this paper, we are searching for a method that has required ability for a large set of queries; the method that would access fewer nodes and would get the answer through a shorter period of time, compared to similar ways; the method which has the ability of matching with similar ways indicator, and can use them to accelerate the queries. We are seeking a method which is able to jump over the useless nodes and produces intermediate data, as compared to similar ones. A method by which nodes processing are not performed directly and automatically through a pattern matching guide.

  2. Recent trends in particle accelerator radiation safety

    The use of particle accelerators in applied and research activities continues to expand, bringing new machines with higher energy and current capabilities which create radiation safety problems not commonly encountered before. An overview is given of these increased ionizing radiation hazards, along with a discussion of some of the new techniques required in evaluating and controlling them. A computer search of the literature provided a relatively comprehensive list of publications describing accelerator radiation safety problems and related subjects

  3. Functional Similarity and Interpersonal Attraction.

    Neimeyer, Greg J.; Neimeyer, Robert A.

    1981-01-01

    Students participated in dyadic disclosure exercises over a five-week period. Results indicated members of high functional similarity dyads evidenced greater attraction to one another than did members of low functional similarity dyads. "Friendship" pairs of male undergraduates displayed greater functional similarity than did "nominal" pairs from…

  4. Contextual Factors for Finding Similar Experts

    Hofmann, Katja; Balog, Krisztian; Bogers, Toine;

    2010-01-01

    -seeking models, are rarely taken into account. In this article, we extend content-based expert-finding approaches with contextual factors that have been found to influence human expert finding. We focus on a task of science communicators in a knowledge-intensive environment, the task of finding similar experts......-centered perspective. The main focus has been on developing content-based algorithms similar to document search. These algorithms identify matching experts primarily on the basis of the textual content of documents with which experts are associated. Other factors, such as the ones identified by expertise......, given an example expert. Our approach combines expertise-seeking and retrieval research. First, we conduct a user study to identify contextual factors that may play a role in the studied task and environment. Then, we design expert retrieval models to capture these factors. We combine these with content-based...

  5. Unifying physics of accelerators, lasers and plasma

    Seryi, Andrei

    2015-01-01

    Unifying Physics of Accelerators, Lasers and Plasma introduces the physics of accelerators, lasers and plasma in tandem with the industrial methodology of inventiveness, a technique that teaches that similar problems and solutions appear again and again in seemingly dissimilar disciplines. This unique approach builds bridges and enhances connections between the three aforementioned areas of physics that are essential for developing the next generation of accelerators.

  6. Performance analysis of acceleration resolution for radar signal

    赵宏钟; 付强

    2003-01-01

    The high acceleration of moving targets has brought severe problems in radar signal processing, such as the decrease in output signal-noise-ratio and the deterioration of Doppler resolution. This paper presents an acceleration ambiguity function (AAF) for characterizing the acceleration effects and the acceleration resolution property in radar signal processing. The definition of the acceleration resolution based on AAF is also presented. Using AAF as an analyzing tool, some factors are derived including the loss factor of output SNR, the broadening factor of Doppler resolution, and the optimal accumulative time (OPT) caused by acceleration in linear-phase matched filtering. The convergent property of quadratic-phase matched-filter for searching for and estimating the acceleration is discussed. The results and conclusions are helpful for the quantitative analysis of the acceleration effects on signal processing, and for evaluation of the performance of acceleration in radar signal waveform design.

  7. Microwave View on Particle Acceleration in Flares

    Fleishman, Gregory D

    2013-01-01

    The thermal-to-nonthermal partition was found to vary greatly from one flare to another resulting in a broad variety of cases from 'heating without acceleration' to 'acceleration without heating'. Recent analysis of microwave data of these differing cases suggests that a similar acceleration mechanism, forming a power-law nonthermal tail up to a few MeV or even higher, operates in all the cases. However, the level of this nonthermal spectrum compared to the original thermal distribution differs significantly from one case to another, implying a highly different thermal-to-nonthermal energy partition in various cases. This further requires a specific mechanism capable of extracting the charged particles from the thermal pool and supplying them to a bulk acceleration process to operate in flares \\textit{in addition} to the bulk acceleration process itself, which, in contrast, efficiently accelerates the seed particles, while cannot accelerate the thermal particles. Within this 'microwave' view on the flare ener...

  8. Accelerating Semogenesis

    Johannessen, Christian Mosbæk; Boeriis, Morten

    2016-01-01

    changes in dynamical constraints on the ecosocial system brought about by the introduction of the electro-digital communication substrate. Through a discussion of the history of photography, specifically contrasting nascent photographic practice with contemporary photography, we argue that the development...... from camera to digital camera and the subsequent consolidation in recent decades of digital cameras into smartphones has had a profound impact, not only on practices of photography, but also on the processes of meaning making with photographic material. We contend that similar processes are changing...

  9. Analytical Searching.

    Pappas, Marjorie L.

    1995-01-01

    Discusses analytical searching, a process that enables searchers of electronic resources to develop a planned strategy by combining words or phrases with Boolean operators. Defines simple and complex searching, and describes search strategies developed with Boolean logic and truncation. Provides guidelines for teaching students analytical…

  10. A new adaptive fast motion estimation algorithm based on local motion similarity degree (LMSD)

    LIU Long; HAN Chongzhao; BAI Yan

    2005-01-01

    In the motion vector field adaptive search technique (MVFAST) and the predictive motion vector field adaptive search technique (PMVFAST), the size of the largest motion vector from the three adjacent blocks (left, top, top-right) is compared with the threshold to select different search scheme. But a suitable search center and search pattern will not be selected in the adaptive search technique when the adjacent motion vectors are not coherent in local region. This paper presents an efficient adaptive search algorithm. The motion vector variation degree (MVVD) is considered a reasonable factor for adaptive search selection. By the relationship between local motion similarity degree (LMSD) and the variation degree of motion vector (MVVD), the motion vectors are classified as three categories according to corresponding LMSD; then different proposed search schemes are adopted for motion estimation. The experimental results show that the proposed algorithm has a significant computational speedup compared with MVFAST and PMVFAST algorithms, and offers a similar, even better performance.

  11. A COMPARISON OF SEMANTIC SIMILARITY MODELS IN EVALUATING CONCEPT SIMILARITY

    Q. X. Xu

    2012-08-01

    Full Text Available The semantic similarities are important in concept definition, recognition, categorization, interpretation, and integration. Many semantic similarity models have been established to evaluate semantic similarities of objects or/and concepts. To find out the suitability and performance of different models in evaluating concept similarities, we make a comparison of four main types of models in this paper: the geometric model, the feature model, the network model, and the transformational model. Fundamental principles and main characteristics of these models are introduced and compared firstly. Land use and land cover concepts of NLCD92 are employed as examples in the case study. The results demonstrate that correlations between these models are very high for a possible reason that all these models are designed to simulate the similarity judgement of human mind.

  12. Learning Multi-modal Similarity

    McFee, Brian

    2010-01-01

    In many applications involving multi-media data, the definition of similarity between items is integral to several key tasks, e.g., nearest-neighbor retrieval, classification, and recommendation. Data in such regimes typically exhibits multiple modalities, such as acoustic and visual content of video. Integrating such heterogeneous data to form a holistic similarity space is therefore a key challenge to be overcome in many real-world applications. We present a novel multiple kernel learning technique for integrating heterogeneous data into a single, unified similarity space. Our algorithm learns an optimal ensemble of kernel transfor- mations which conform to measurements of human perceptual similarity, as expressed by relative comparisons. To cope with the ubiquitous problems of subjectivity and inconsistency in multi- media similarity, we develop graph-based techniques to filter similarity measurements, resulting in a simplified and robust training procedure.

  13. Pulsed DC accelerator for laser wakefield accelerator

    For the acceleration of ultra-short, high-brightness electron bunches, a pulsed DC accelerator was constructed. The pulser produced megavolt pulses of 1 ns duration in a vacuum diode. Results are presented from field emission of electrons in the diode. The results indicate that the accelerating gradient in the diode is approximately 1.5 GV/m

  14. Linear Accelerator (LINAC)

    ... News Physician Resources Professions Site Index A-Z Linear Accelerator A linear accelerator (LINAC) customizes high energy x-rays to ... ensured? What is this equipment used for? A linear accelerator (LINAC) is the device most commonly used ...

  15. Roget's Thesaurus and Semantic Similarity

    Jarmasz, Mario; Szpakowicz, Stan

    2012-01-01

    We have implemented a system that measures semantic similarity using a computerized 1987 Roget's Thesaurus, and evaluated it by performing a few typical tests. We compare the results of these tests with those produced by WordNet-based similarity measures. One of the benchmarks is Miller and Charles' list of 30 noun pairs to which human judges had assigned similarity measures. We correlate these measures with those computed by several NLP systems. The 30 pairs can be traced back to Rubenstein ...

  16. Aggregated search: a new information retrieval paradigm

    Kopliku, Arlind; Pinel-Sauvagnat, Karen; Boughanem, Mohand

    2014-01-01

    Traditional search engines return ranked lists of search results. It is up to the user to scroll this list, scan within different documents and assemble information that fulfill his/her information need. Aggregated search represents a new class of approaches where the information is not only retrieved but also assembled. This is the current evolution in Web search, where diverse content (images, videos, ...) and relational content (similar entities, features) are included in search results. I...

  17. Simrank: Rapid and sensitive general-purpose k-mer search tool

    DeSantis, T.Z.; Keller, K.; Karaoz, U.; Alekseyenko, A.V; Singh, N.N.S.; Brodie, E.L; Pei, Z.; Andersen, G.L; Larsen, N.

    2011-04-01

    Terabyte-scale collections of string-encoded data are expected from consortia efforts such as the Human Microbiome Project (http://nihroadmap.nih.gov/hmp). Intra- and inter-project data similarity searches are enabled by rapid k-mer matching strategies. Software applications for sequence database partitioning, guide tree estimation, molecular classification and alignment acceleration have benefited from embedded k-mer searches as sub-routines. However, a rapid, general-purpose, open-source, flexible, stand-alone k-mer tool has not been available. Here we present a stand-alone utility, Simrank, which allows users to rapidly identify database strings the most similar to query strings. Performance testing of Simrank and related tools against DNA, RNA, protein and human-languages found Simrank 10X to 928X faster depending on the dataset. Simrank provides molecular ecologists with a high-throughput, open source choice for comparing large sequence sets to find similarity.

  18. Prospects for searching axion-like particle dark matter with dipole, toroidal and wiggler magnets

    Baker, Oliver K. [Yale Univ., New Haven, CT (United States). Dept. of Physics; Betz, Michael; Caspers, Fritz [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Jaeckel, Joerg [Institute for Particle Physics Phenomenology, Durham (United Kingdom); Lindner, Axel; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Semertzidis, Yannis [Brookhaven National Lab., Upton, NY (United States); Sikivie, Pierre [Florida Univ., Gainesville, FL (United States). Dept. of Physics; Zioutas, Konstantin [Patras Univ. (Greece)

    2011-10-15

    In this work we consider searches for dark matter made of axions or axion-like particles (ALPs) using resonant radio frequency cavities inserted into dipole magnets from particle accelerators, wiggler magnets developed for accelerator based advanced light sources, and toroidal magnets similar to those used in particle physics detectors. We investigate the expected sensitivity of such ALP dark matter detectors and discuss the engineering aspects of building and tuning them. Brief mention is also made of even stronger field magnets that are becoming available due to improvements in magnetic technology. It is concluded that new experiments utilizing already existing magnets could greatly enlarge the mass region in searches for axion-like dark matter particles. (orig.)

  19. Prospects for searching axionlike particle dark matter with dipole, toroidal, and wiggler magnets

    Baker, Oliver K; Caspers, Fritz; Jaeckel, Joerg; Lindner, Axel; Ringwald, Andreas; Semertzidis, Yannis; Sikivie, Pierre; Zioutas, Konstantin

    2012-01-01

    In this work, we consider searches for dark matter made of axions or axionlike particles using resonant radio frequency cavities inserted into dipole magnets from particle accelerators, wiggler magnets developed for accelerator based advanced light sources, and toroidal magnets similar to those used in particle-physics detectors. We investigate the expected sensitivity of such axionlike-particle dark matter detectors and discuss the engineering aspects of building and tuning them. Brief mention is also made of even stronger field magnets which are becoming available due to improvements in magnetic technology. It is concluded that new experiments utilizing already-existing magnets could greatly enlarge the mass region in searches for axionlike dark matter particles.

  20. Prospects for searching axion-like particle dark matter with dipole, toroidal and wiggler magnets

    In this work we consider searches for dark matter made of axions or axion-like particles (ALPs) using resonant radio frequency cavities inserted into dipole magnets from particle accelerators, wiggler magnets developed for accelerator based advanced light sources, and toroidal magnets similar to those used in particle physics detectors. We investigate the expected sensitivity of such ALP dark matter detectors and discuss the engineering aspects of building and tuning them. Brief mention is also made of even stronger field magnets that are becoming available due to improvements in magnetic technology. It is concluded that new experiments utilizing already existing magnets could greatly enlarge the mass region in searches for axion-like dark matter particles. (orig.)

  1. Improving gene expression similarity measurement using pathway-based analytic dimension

    2009-01-01

    Background Gene expression similarity measuring methods were developed and applied to search rapidly growing public microarray databases. However, current expression similarity measuring methods need to be improved to accurately measure similarity between gene expression profiles from different platforms or different experiments. Results We devised new gene expression similarity measuring method based on pathway information. In short, newly devised method measure similarity between gene expre...

  2. Search and Recommendation

    Bogers, Toine

    2014-01-01

    In just a little over half a century, the field of information retrieval has experienced spectacular growth and success, with IR applications such as search engines becoming a billion-dollar industry in the past decades. Recommender systems have seen an even more meteoric rise to success with wide......-scale application by companies like Amazon, Facebook, and Netflix. But are search and recommendation really two different fields of research that address different problems with different sets of algorithms in papers published at distinct conferences? In my talk, I want to argue that search and recommendation are...... more similar than they have been treated in the past decade. By looking more closely at the tasks and problems that search and recommendation try to solve, at the algorithms used to solve these problems and at the way their performance is evaluated, I want to show that there is no clear black and white...

  3. Personalized recommendation with corrected similarity

    Personalized recommendation has attracted a surge of interdisciplinary research. Especially, similarity-based methods in applications of real recommendation systems have achieved great success. However, the computations of similarities are overestimated or underestimated, in particular because of the defective strategy of unidirectional similarity estimation. In this paper, we solve this drawback by leveraging mutual correction of forward and backward similarity estimations, and propose a new personalized recommendation index, i.e., corrected similarity based inference (CSI). Through extensive experiments on four benchmark datasets, the results show a greater improvement of CSI in comparison with these mainstream baselines. And a detailed analysis is presented to unveil and understand the origin of such difference between CSI and mainstream indices. (paper)

  4. OpenMP for Accelerators

    Beyer, J C; Stotzer, E J; Hart, A; de Supinski, B R

    2011-03-15

    OpenMP [13] is the dominant programming model for shared-memory parallelism in C, C++ and Fortran due to its easy-to-use directive-based style, portability and broad support by compiler vendors. Similar characteristics are needed for a programming model for devices such as GPUs and DSPs that are gaining popularity to accelerate compute-intensive application regions. This paper presents extensions to OpenMP that provide that programming model. Our results demonstrate that a high-level programming model can provide accelerated performance comparable to hand-coded implementations in CUDA.

  5. Relativistic blast waves that accelerate

    An approximate analytical similarity solution is derived for the problem of an ultrarelativistic, adiabatic blast wave which results from a point explosion at the origin of a cold (i.e., nonrelativistic), spherically symmetric gas in which the density decreases fast enough with radius to accelerate the shock wave toward larger radii. This solution includes both the shock propagation law and the details of the postshock flow. It is revelant to models of compact, extragalactic radio sources involving relativistic shock waves, as well as to the supernova shock model for cosmic ray acceleration

  6. CAS CERN Accelerator School: Fourth general accelerator physics course

    The fourth CERN Accelerator School (CAS) basic course on General Accelerator Physics was given at KFA, Juelich, from 17 to 28 September 1990. Its syllabus was based on the previous similar courses held at Gif-sur-Yvette in 1984, Aarhus 1986, and Salamanca 1988, and whose proceedings were published as CERN Reports 85-19, 87-10, and 89-05, respectively. However, certain topics were treated in a different way, improved or extended, while new subjects were introduced. All of these appear in the present proceedings, which include lectures or seminars on the history and applications of accelerators, phase space and emittance, chromaticity, beam-beam effects, synchrotron radiation, radiation damping, tune measurement, transition, electron cooling, the designs of superconducting magnets, ring lattices, conventional RF cavities and ring RF systems, and an introduction to cyclotrons. (orig.)

  7. Self-similar aftershock rates

    Davidsen, Jörn

    2016-01-01

    In many important systems exhibiting crackling noise --- intermittent avalanche-like relaxation response with power-law and, thus, self-similar distributed event sizes --- the "laws" for the rate of activity after large events are not consistent with the overall self-similar behavior expected on theoretical grounds. This is in particular true for the case of seismicity and a satisfying solution to this paradox has remained outstanding. Here, we propose a generalized description of the aftershock rates which is both self-similar and consistent with all other known self-similar features. Comparing our theoretical predictions with high resolution earthquake data from Southern California we find excellent agreement, providing in particular clear evidence for a unified description of aftershocks and foreshocks. This may offer an improved way of time-dependent seismic hazard assessment and earthquake forecasting.

  8. Learning Multi-modal Similarity

    McFee, Brian; Lanckriet, Gert

    2010-01-01

    In many applications involving multi-media data, the definition of similarity between items is integral to several key tasks, e.g., nearest-neighbor retrieval, classification, and recommendation. Data in such regimes typically exhibits multiple modalities, such as acoustic and visual content of video. Integrating such heterogeneous data to form a holistic similarity space is therefore a key challenge to be overcome in many real-world applications. We present a novel multiple kernel learning t...

  9. Similarity measures for protein ensembles

    Lindorff-Larsen, Kresten; Ferkinghoff-Borg, Jesper

    2009-01-01

    Analyses of similarities and changes in protein conformation can provide important information regarding protein function and evolution. Many scores, including the commonly used root mean square deviation, have therefore been developed to quantify the similarities of different protein conformations...... synthetic example from molecular dynamics simulations. We then apply the algorithms to revisit the problem of ensemble averaging during structure determination of proteins, and find that an ensemble refinement method is able to recover the correct distribution of conformations better than standard single...

  10. SELF-SIMILAR TRAFFIC GENERATOR

    Linawati Linawati; I Made Suartika

    2009-01-01

    Network traffic generator can be produced using OPNET. OPNET generates the traffic as explicit traffic or background traffic. This paper demonstrates generating traffic in OPNET 7.0 as background traffic. The traffi generator that was simulated is self-similar traffic with different Hurst parameter. The simulation results proved that OPNET with background traffic function can be as a qualified self-similar traffic generator. These results can help in investigating and analysing network perfor...

  11. Molecular similarity of MDR inhibitors

    Simon Gibbons; Mire Zloh

    2004-01-01

    Abstract: The molecular similarity of multidrug resistance (MDR) inhibitors was evaluated using the point centred atom charge approach in an attempt to find some common features of structurally unrelated inhibitors. A series of inhibitors of bacterial MDR were studied and there is a high similarity between these in terms of their shape, presence and orientation of aromatic ring moieties. A comparison of the lipophilic properties of these molecules has also been conducted suggesting that this ...

  12. HOW DISSIMILARLY SIMILAR ARE BIOSIMILARS?

    Ramshankar Vijayalakshmi; Kesavan Sabitha; Krishnamurthy Arvind

    2012-01-01

    Recently Biopharmaceuticals are the new chemotherapeutical agents that are called as “Biosimilars” or “follow on protein products” by the European Medicines Agency (EMA) and the American regulatory agencies (Food and Drug Administration) respectively. Biosimilars are extremely similar to the reference molecule but not identical, however close their similarities may be. A regulatory framework is therefore in place to assess the application for marketing authorisation of biosimilars. When a bi...

  13. Method of similarity for cavitation

    The knowledge of possible cavitation in subassembly nozzles of the fast reactor core implies the realization of a fluid dynamic model test. We propose a method of similarity based on the non-dimensionalization of the equation of motion for viscous capillarity fluid issued from the Cahn and Hilliard model. Taking into account the dissolved gas effect, a condition of compatibility is determined. This condition must be respected by the fluid in experiment, along with the scaling between the two similar flows. (author)

  14. Supervised Learning with Similarity Functions

    Kar, Purushottam; Jain, Prateek

    2012-01-01

    We address the problem of general supervised learning when data can only be accessed through an (indefinite) similarity function between data points. Existing work on learning with indefinite kernels has concentrated solely on binary/multi-class classification problems. We propose a model that is generic enough to handle any supervised learning task and also subsumes the model previously proposed for classification. We give a "goodness" criterion for similarity functions w.r.t. a given superv...

  15. Faceted Search

    Tunkelang, Daniel

    2009-01-01

    We live in an information age that requires us, more than ever, to represent, access, and use information. Over the last several decades, we have developed a modern science and technology for information retrieval, relentlessly pursuing the vision of a "memex" that Vannevar Bush proposed in his seminal article, "As We May Think." Faceted search plays a key role in this program. Faceted search addresses weaknesses of conventional search approaches and has emerged as a foundation for interactive information retrieval. User studies demonstrate that faceted search provides more

  16. Are search committees really searching?

    Hoffmeir, Patricia A

    2003-02-01

    Academic chair searches are admittedly a labor-intensive process, but they are made more difficult and often lead to less-than-optimal outcomes because search committees spend their time "advertising," "looking," but not truly searching for academic chairs. At the onset, certain "realities" must be acknowledged, including (1) understanding that unless your organization is renowned in the specialty for which you are conducting the search, candidates won't be pounding at your door for a job, (2) searches that fail to include an overall assessment of the department in question are likely to miss the mark, (3) chairs must have demonstrated not only clinical expertise but also business savvy, (4) the best candidate is not necessarily someone who is already a department chair, (5) when it comes to chair searches, it's a buyer's market, and (6) the search process is inextricably linked to the success of the search. Key to the process of conducting an academic chair search are the judicious formation of the search committee; committee members' willingness to do their homework, attend all committee meeting, and keep the committee's activities confidential; crafting, not revising, the current job description for the open chair position; interviewing viable candidates rather than all candidates and adhering to a coordinated interviewing process; and evaluating internal and external candidates according to the same parameters. PMID:12584089

  17. Status of Searches for Magnetic Monopoles

    Patrizii, L

    2015-01-01

    The searches for magnetic monopoles (Ms) is a fascinating interdisciplinary field with implications in fundamental theories, in particle physics, astrophysics, and cosmology. The quantum theory of Ms and its consistency with electrodynamics was derived by Dirac. This marked the start of the searches for classical monopoles at every new accelerator, up to the LHC. Magnetic monopoles are required by Grand Unification Theories, but unlike classical monopoles they would be incredibly massive, out of the reach of any conceivable accelerator. Large efforts have been made to search for them in the cosmic radiation as relic particles from the early Universe in the widest range of mass and velocity experimentally accessible. In this paper the status of the searches for classical Ms at accelerators, for GUT, superheavy Ms in the penetrating cosmic radiation and for Intermediate Mass Ms at high altitudes is discussed, with emphasis on the most recent results and future perspectives.

  18. Representation is representation of similarities.

    Edelman, S

    1998-08-01

    Advanced perceptual systems are faced with the problem of securing a principled (ideally, veridical) relationship between the world and its internal representation. I propose a unified approach to visual representation, addressing the need for superordinate and basic-level categorization and for the identification of specific instances of familiar categories. According to the proposed theory, a shape is represented internally by the responses of a small number of tuned modules, each broadly selective for some reference shape, whose similarity to the stimulus it measures. This amounts to embedding the stimulus in a low-dimensional proximal shape space spanned by the outputs of the active modules. This shape space supports representations of distal shape similarities that are veridical as Shepard's (1968) second-order isomorphisms (i.e., correspondence between distal and proximal similarities among shapes, rather than between distal shapes and their proximal representations). Representation in terms of similarities to reference shapes supports processing (e.g., discrimination) of shapes that are radically different from the reference ones, without the need for the computationally problematic decomposition into parts required by other theories. Furthermore, a general expression for similarity between two stimuli, based on comparisons to reference shapes, can be used to derive models of perceived similarity ranging from continuous, symmetric, and hierarchical ones, as in multidimensional scaling (Shepard 1980), to discrete and nonhierarchical ones, as in the general contrast models (Shepard & Arabie 1979; Tversky 1977). PMID:10097019

  19. TM01 mode accelerating cavity optimization

    The cost of an accelerator depends greatly upon the effective use of rf power for particle acceleration. Before completing an accelerator design, an optimization of the accelerating cells relative to the effective shunt impedance should be made to measure the structure's efficiency in providing a high and effective acceleration of particles for a given rf power. Optimization of the accelerating cell resonant at f/sub r/ = 1350 MHz (TM01 mode) relative to the maximum effective shunt impedance ZT2 was performed at the Los Alamos Scientific Laboratory using the computer program SUPERFISH. The study was parametric; one parameter was changed while the others were held constant. Frequency adjustments were made by changing the cavity radius. Results presented in this report can be used to design similar cavities at different resonant frequencies or to design a more complicated cavity (TM02 mode) for the disk and washer structure

  20. Accelerating cosmologies from exponential potentials

    It is learnt that exponential potentials of the form V ∼ exp(-2cφ/Mp) arising from the hyperbolic or flux compactification of higher-dimensional theories are of interest for getting short periods of accelerated cosmological expansions. Using a similar potential but derived for the combined case of hyperbolic-flux compactification, we study a four-dimensional flat (or open) FRW cosmologies and give analytic (and numerical) solutions with exponential behavior of scale factors. We show that, for the M-theory motivated potentials, the cosmic acceleration of the universe can be eternal if the spatial curvature of the 4d spacetime is negative, while the acceleration is only transient for a spatially flat universe. We also briefly discuss about the mass of massive Kaluza-Klein modes and the dynamical stabilization of the compact hyperbolic extra dimensions. (author)

  1. Acceleration without Horizons

    Doria, Alaric; Munoz, Gerardo

    2015-01-01

    We derive the metric of an accelerating observer moving with non-constant proper acceleration in flat spacetime. With the exception of a limiting case representing a Rindler observer, there are no horizons. In our solution, observers can accelerate to any desired terminal speed $v_{\\infty} < c$. The motion of the accelerating observer is completely determined by the distance of closest approach and terminal velocity or, equivalently, by an acceleration parameter and terminal velocity.

  2. A New Search for $ \

    Dore, U; Kodama, K; Ushida, N; Loverre, P F

    2002-01-01

    % WA95\\\\ \\\\ The question whether neutrino flavours mix at some level - and the related question whether neutrinos have non-zero mass - is one of the remaining great challenges of experimental physics. Neutrinos from supernovae, from the sun, from the earth's atmosphere, from nuclear reactors and from radioactive decays are currently under study; in this frame, experiments using accelerators play a privileged role because the well known neutrino source properties allow high precision measurements and background control.\\\\ \\\\The main goal of the CHORUS experiment is to search for neutrino oscillations in the $\

  3. VEDs for charged particle accelerators: Indian scenario

    In the initial times after their invention, the charged particle accelerators have, primarily, been used for fundamental studies on nuclei and atoms. From the first modern accelerator, the cathode ray tube, used by J.J. Thomson for the discovery of electron, very recently the gigantic 27 km circumference Large Hadron Collider (LHC) is operational in the search of Higg's boson and related physics issues. Particle accelerators have emerged as powerful microscopes for investigating the finest details of cells, genes, molecules, atoms, protons, neutrons, muons, electrons, quarks and, possibly, still undiscovered even more fundamental constituents of the universe, such as dark matter and dark energy. Several noble prize winning discoveries have been made using accelerators. Accelerators are now being used in a wide area of industrial and medical applications. They are used for the production of radioisotopes for medical imaging, cancer therapy, food sterilization, treatment of waste water, sterilization of medical equipment, material modification, mass spectroscopy, cargo scanning, fabrication of semiconductors etc. Ongoing effort towards the development of accelerators with megawatt beam power is showing hope for a cleaner source of nuclear energy and treatment of nuclear waste. Several tens of thousands of accelerators are presently operational in the world for basic research and applications. Development of new accelerators has several times been driven by new technologies and materials and sometimes they have driven the technological developments towards cutting edge. Some examples are ultra-high vacuum in large volumes, superfluid helium in cryogenics, cryocoolers, superconducting magnets and RF cavities, high power vacuum electronic devices, global control systems, superfast computing and communication networks, giant data storage/processing systems etc. India has been pursuing a fairly robust programme of accelerator development at various institutions. It

  4. BIOCONAID System (Bionic Control of Acceleration Induced Dimming). Final Report.

    Rogers, Dana B.; And Others

    The system described represents a new technique for enhancing the fidelity of flight simulators during high acceleration maneuvers. This technique forces the simulator pilot into active participation and energy expenditure similar to the aircraft pilot undergoing actual accelerations. The Bionic Control of Acceleration Induced Dimming (BIOCONAID)…

  5. Similarity measures for face recognition

    Vezzetti, Enrico

    2015-01-01

    Face recognition has several applications, including security, such as (authentication and identification of device users and criminal suspects), and in medicine (corrective surgery and diagnosis). Facial recognition programs rely on algorithms that can compare and compute the similarity between two sets of images. This eBook explains some of the similarity measures used in facial recognition systems in a single volume. Readers will learn about various measures including Minkowski distances, Mahalanobis distances, Hansdorff distances, cosine-based distances, among other methods. The book also summarizes errors that may occur in face recognition methods. Computer scientists "facing face" and looking to select and test different methods of computing similarities will benefit from this book. The book is also useful tool for students undertaking computer vision courses.

  6. Dusty-Plasma Particle Accelerator

    Foster, John E.

    2005-01-01

    A dusty-plasma apparatus is being investigated as means of accelerating nanometer- and micrometer-sized particles. Applications for the dusty-plasma particle accelerators fall into two classes: Simulation of a variety of rapidly moving dust particles and micrometeoroids in outer-space environments that include micrometeoroid streams, comet tails, planetary rings, and nebulae and Deposition or implantation of nanoparticles on substrates for diverse industrial purposes that could include hardening, increasing thermal insulation, altering optical properties, and/or increasing permittivities of substrate materials. Relative to prior apparatuses used for similar applications, dusty-plasma particle accelerators offer such potential advantages as smaller size, lower cost, less complexity, and increased particle flux densities. A dusty-plasma particle accelerator exploits the fact that an isolated particle immersed in plasma acquires a net electric charge that depends on the relative mobilities of electrons and ions. Typically, a particle that is immersed in a low-temperature, partially ionized gas, wherein the average kinetic energy of electrons exceeds that of ions, causes the particle to become negatively charged. The particle can then be accelerated by applying an appropriate electric field. A dusty-plasma particle accelerator (see figure) includes a plasma source such as a radio-frequency induction discharge apparatus containing (1) a shallow cup with a biasable electrode to hold the particles to be accelerated and (2) a holder for the substrate on which the particles are to impinge. Depending on the specific design, a pair of electrostatic-acceleration grids between the substrate and discharge plasma can be used to both collimate and further accelerate particles exiting the particle holder. Once exposed to the discharge plasma, the particles in the cup quickly acquire a negative charge. Application of a negative voltage pulse to the biasable electrode results in the

  7. Accelerator and Ion Beam Tradeoffs for Studies of Warm Dense Matter

    One approach for heating a target to ''Warm Dense Matter'' conditions (similar, for example, to the interiors of giant planets or certain stages in Inertial Confinement Fusion targets), is to use intense ion beams as the heating source (see refs.[6] and [7] and references therein for motivation and accelerator concepts). By consideration of ion beam phase space constraints, both at the injector, and at the final focus, and consideration of simple equations of state and relations for ion stopping, approximate conditions at a target foil may be calculated. Thus target temperature and pressure may be calculated as a function of ion mass, ion energy, pulse duration, velocity tilt, and other accelerator parameters. We connect some of these basic parameters to help search the extensive parameter space (including ion mass, ion energy, total charge in beam pulse, beam emittance, target thickness and density)

  8. Similarity Measures for Comparing Biclusterings.

    Horta, Danilo; Campello, Ricardo J G B

    2014-01-01

    The comparison of ordinary partitions of a set of objects is well established in the clustering literature, which comprehends several studies on the analysis of the properties of similarity measures for comparing partitions. However, similarity measures for clusterings are not readily applicable to biclusterings, since each bicluster is a tuple of two sets (of rows and columns), whereas a cluster is only a single set (of rows). Some biclustering similarity measures have been defined as minor contributions in papers which primarily report on proposals and evaluation of biclustering algorithms or comparative analyses of biclustering algorithms. The consequence is that some desirable properties of such measures have been overlooked in the literature. We review 14 biclustering similarity measures. We define eight desirable properties of a biclustering measure, discuss their importance, and prove which properties each of the reviewed measures has. We show examples drawn and inspired from important studies in which several biclustering measures convey misleading evaluations due to the absence of one or more of the discussed properties. We also advocate the use of a more general comparison approach that is based on the idea of transforming the original problem of comparing biclusterings into an equivalent problem of comparing clustering partitions with overlapping clusters. PMID:26356865

  9. Approaches to Sequence Similarity Representation

    Sokolov, Artem; Rachkovskij, Dmitri

    2006-01-01

    We discuss several approaches to similarity preserving coding of symbol sequences and possible connections of their distributed versions to metric embeddings. Interpreting sequence representation methods with embeddings can help develop an approach to their analysis and may lead to discovering useful properties.

  10. A square from similar rectangles

    Dorichenko, Sergey; Skopenkov, Mikhail

    2013-01-01

    In the present popular science paper we determine when a square can be dissected into rectangles similar to a given rectangle. The approach to the question is based on a physical interpretation using electrical networks. Only secondary school background is assumed in the paper.

  11. Photonic Crystal Laser Accelerator Structures

    Cowan, Benjamin; Javanmard, Mehdi; Siemann, Robert H.

    2003-01-01

    Photonic crystals have great potential for use as laser-driven accelerator structures. A photonic crystal is a dielectric structure arranged in a periodic geometry. Like a crystalline solid with its electronic band structure, the modes of a photonic crystal lie in a set of allowed photonic bands. Similarly, it is possible for a photonic crystal to exhibit one or more photonic band gaps, with frequencies in the gap unable to propagate in the crystal. Thus photonic crystals can confine an optic...

  12. HOW DISSIMILARLY SIMILAR ARE BIOSIMILARS?

    Ramshankar Vijayalakshmi

    2012-05-01

    Full Text Available Recently Biopharmaceuticals are the new chemotherapeutical agents that are called as “Biosimilars” or “follow on protein products” by the European Medicines Agency (EMA and the American regulatory agencies (Food and Drug Administration respectively. Biosimilars are extremely similar to the reference molecule but not identical, however close their similarities may be. A regulatory framework is therefore in place to assess the application for marketing authorisation of biosimilars. When a biosimilar is similar to the reference biopharmaceutical in terms of safety, quality, and efficacy, it can be registered. It is important to document data from clinical trials with a view of similar safety and efficacy. If the development time for a generic medicine is around 3 years, a biosimilar takes about 6-9 years. Generic medicines need to demonstrate bioequivalence only unlike biosimilars that need to conduct phase I and Phase III clinical trials. In this review, different biosimilars that are already being used successfully in the field on Oncology is discussed. Their similarity, differences and guidelines to be followed before a clinically informed decision to be taken, is discussed. More importantly the regulatory guidelines that are operational in India with a work flow of making a biosimilar with relevant dos and dont’s are discussed. For a large populous country like India, where with improved treatments in all sectors including oncology, our ageing population is increasing. For the health care of this sector, we need more newer, cheaper and effective biosimilars in the market. It becomes therefore important to understand the regulatory guidelines and steps to come up with more biosimilars for the existing population and also more information is mandatory for the practicing clinicians to translate these effectively into clinical practice.

  13. High intensity hadron accelerators

    In this paper we give an introductory discussion of high intensity hadron accelerators with special emphasis on the high intensity feature. The topics selected for this discussion are: Types of acclerator - The principal actions of an accelerator are to confine and to accelerate a particle beam. Focusing - This is a discussion of the confinement of single particles. Intensity limitations - These are related to confinement of intense beams of particles. Power economics - Considerations related to acceleration of intense beams of particles. Heavy ion kinematics - The adaptation of accelerators to accelerate all types of heavy ions

  14. The direction of acceleration

    Wilhelm, Thomas; Burde, Jan-Philipp; Lück, Stephan

    2015-11-01

    Acceleration is a physical quantity that is difficult to understand and hence its complexity is often erroneously simplified. Many students think of acceleration as equivalent to velocity, a ˜ v. For others, acceleration is a scalar quantity, which describes the change in speed Δ|v| or Δ|v|/Δt (as opposed to the change in velocity). The main difficulty with the concept of acceleration therefore lies in developing a correct understanding of its direction. The free iOS app AccelVisu supports students in acquiring a correct conception of acceleration by showing acceleration arrows directly at moving objects.

  15. 2014 CERN Accelerator Schools: Plasma Wake Acceleration

    2014-01-01

    A specialised school on Plasma Wake Acceleration will be held at CERN, Switzerland from 23-29 November, 2014.   This course will be of interest to staff and students in accelerator laboratories, university departments and companies working in or having an interest in the field of new acceleration techniques. Following introductory lectures on plasma and laser physics, the course will cover the different components of a plasma wake accelerator and plasma beam systems. An overview of the experimental studies, diagnostic tools and state of the art wake acceleration facilities, both present and planned, will complement the theoretical part. Topical seminars and a visit of CERN will complete the programme. Further information can be found at: http://cas.web.cern.ch/cas/PlasmaWake2014/CERN-advert.html http://indico.cern.ch/event/285444/

  16. Accelerator probes for new stable quarks

    Belostky, Konstantin M; Shibaev, Konstantin I

    2011-01-01

    The nonbaryonic dark matter of the Universe can consist of new stable double charged particles $O^{--}$, bound with primordial helium in heavy neutral O-helium (OHe)"atoms" by ordinary Coulomb interaction. O-helium dark atoms can play the role of specific nuclear interacting dark matter and provide solution for the puzzles of dark matter searches. The successful development of composite dark matter scenarios appeals to experimental search for the charged constituents of dark atoms. If $O^{--}$ is a "heavy quark cluster" $\\bar U \\bar U \\bar U$, its production at accelerators is virtually impossible and the strategy of heavy quark search is reduced to search for heavy stable hadrons, containing only single heavy quark (or antiquark). Estimates of production cross section of such particles at LHC are presented and the experimental signatures for new stable quarks are outlined.

  17. Retrieval of similar chess positions

    Ganguly, Debasis; LEVELING, JOHANNES; Jones, Gareth J.F.

    2014-01-01

    We address the problem of retrieving chess game positions similar to a given query position from a collection of archived chess games. We investigate this problem from an information retrieval (IR) perspective. The advantage of our proposed IR-based approach is that it allows using the standard inverted organization of stored chess positions, leading to an ecient retrieval. Moreover, in contrast to retrieving exactly identical board positions, the IR-based approach is able to provide approxim...

  18. Interfacial Molecular Searching Using Forager Dynamics

    Monserud, Jon H.; Schwartz, Daniel K.

    2016-03-01

    Many biological and technological systems employ efficient non-Brownian intermittent search strategies where localized searches alternate with long flights. Coincidentally, molecular species exhibit intermittent behavior at the solid-liquid interface, where periods of slow motion are punctuated by fast flights through the liquid phase. Single-molecule tracking was used here to observe the interfacial search process of DNA for complementary DNA. Measured search times were qualitatively consistent with an intermittent-flight model, and ˜10 times faster than equivalent Brownian searches, suggesting that molecular searches for reactive sites benefit from similar efficiencies as biological organisms.

  19. SPATIO-TEXTUAL SIMILARITY JOIN

    Ch Shylaja and Supreethi K.P

    2015-07-01

    Full Text Available Data mining is the process of discovering interesting patterns and knowledge from large amounts of data. Spatial databases store large space related data, such as maps, preprocessed remote sensing or medical imaging data. Modern mobile phones and mobile devices are equipped with GPS devices; this is the reason for the Location based services to gain significant attention. These Location based services generate large amounts of spatio- textual data which contain both spatial location and textual description. The spatiotextual objects have different representations because of deviations in GPS or due to different user descriptions. This calls for the need of efficient methods to integrate spatio-textual data. Spatio-textual similarity join meets this need. Spatio-textual similarity join: Given two sets of spatio-textual data, it finds all the similar pairs. Filter and refine framework will be developed to device the algorithms. The prefix filter technique will be extended to generate spatial and textual signatures and inverted indexes will be built on top of these signatures. Candidate pairs will be found using these indexes. Finally the candidate pairs will be refined to get the result. MBR-prefix based signature will be used to prune dissimilar objects. Hybrid signature will be used to support spatial and textual pruning simultaneously.

  20. Roget's Thesaurus and Semantic Similarity

    Jarmasz, Mario

    2012-01-01

    We have implemented a system that measures semantic similarity using a computerized 1987 Roget's Thesaurus, and evaluated it by performing a few typical tests. We compare the results of these tests with those produced by WordNet-based similarity measures. One of the benchmarks is Miller and Charles' list of 30 noun pairs to which human judges had assigned similarity measures. We correlate these measures with those computed by several NLP systems. The 30 pairs can be traced back to Rubenstein and Goodenough's 65 pairs, which we have also studied. Our Roget's-based system gets correlations of .878 for the smaller and .818 for the larger list of noun pairs; this is quite close to the .885 that Resnik obtained when he employed humans to replicate the Miller and Charles experiment. We further evaluate our measure by using Roget's and WordNet to answer 80 TOEFL, 50 ESL and 300 Reader's Digest questions: the correct synonym must be selected amongst a group of four words. Our system gets 78.75%, 82.00% and 74.33% of ...

  1. Landscape similarity, retrieval, and machine mapping of physiographic units

    Jasiewicz, Jaroslaw; Netzel, Pawel; Stepinski, Tomasz F.

    2014-09-01

    We introduce landscape similarity - a numerical measure that assesses affinity between two landscapes on the basis of similarity between the patterns of their constituent landform elements. Such a similarity function provides core technology for a landscape search engine - an algorithm that parses the topography of a study area and finds all places with landscapes broadly similar to a landscape template. A landscape search can yield answers to a query in real time, enabling a highly effective means to explore large topographic datasets. In turn, a landscape search facilitates auto-mapping of physiographic units within a study area. The country of Poland serves as a test bed for these novel concepts. The topography of Poland is given by a 30 m resolution DEM. The geomorphons method is applied to this DEM to classify the topography into ten common types of landform elements. A local landscape is represented by a square tile cut out of a map of landform elements. A histogram of cell-pair features is used to succinctly encode the composition and texture of a pattern within a local landscape. The affinity between two local landscapes is assessed using the Wave-Hedges similarity function applied to the two corresponding histograms. For a landscape search the study area is organized into a lattice of local landscapes. During the search the algorithm calculates the similarity between each local landscape and a given query. Our landscape search for Poland is implemented as a GeoWeb application called TerraEx-Pl and is available at http://sil.uc.edu/. Given a sample, or a number of samples, from a target physiographic unit the landscape search delineates this unit using the principles of supervised machine learning. Repeating this procedure for all units yields a complete physiographic map. The application of this methodology to topographic data of Poland results in the delineation of nine physiographic units. The resultant map bears a close resemblance to a conventional

  2. Searching for heavy leptons

    This frankly speculative paper discusses ways in which leptons heavier than the tau (if they exist) might be found. The status of the tau is briefly reviewed, and methods for searching for sequential charged leptons beyond the tau and other charged leptons at PEP, PETRA, and CESR are sketched. Charged leptons with mass greater than 20 GeV/c2 might be found at proton accelerators in hadron-hadron, photon-hadron, or ν-hadron collisions. Unstable, neutral heavy leptons might have unique, conserved lepton number or nonunique lepton number. The most difficult leptons to detect are stable neutral heavy leptons; nevertheless, a possible detection method is suggested. The obvious solution to seeking the postulated leptons is an e+e- colliding beam storage ring with c.m. energy = several hundred GeV. Until such a machine is built, one can employ Z0 → L+ + L-; the use of R/sub Z0/ and GAMMA/sub Z0/ in this connection is discussed. If heavier Z0's exist, the heavy lepton search can be extended to higher energies. Another solution for producing these leptons involves the use of clashing e+e- linear accelerators. Characteristics of storage rings are compared with those of clashing linacs; a general description is given of the proposed SLAC Linac-Collider, along with the physics that could be done at such a machine. 6 figures

  3. Low voltage electron beam accelerators

    Widely used electron accelerators in industries are the electron beams with acceleration voltage at 300 kV or less. The typical examples are shown on manufactures in Japan, equipment configuration, operation, determination of process parameters, and basic maintenance requirement of the electron beam processors. New electron beam processors with acceleration voltage around 100 kV were introduced maintaining the relatively high dose speed capability of around 10,000 kGy x mpm at production by ESI (Energy Science Inc. USA, Iwasaki Electric Group). The application field like printing and coating for packaging requires treating thickness of 30 micron or less. It does not require high voltage over 110 kV. Also recently developed is a miniature bulb type electron beam tube with energy less than 60 kV. The new application area for this new electron beam tube is being searched. The drive force of this technology to spread in the industries would be further development of new application, process and market as well as the price reduction of the equipment, upon which further acknowledgement and acceptance of the technology to societies and industries would entirely depend. (Y. Tanaka)

  4. Low voltage electron beam accelerators

    Ochi, Masafumi [Iwasaki Electric Co., Ltd., Tokyo (Japan)

    2003-02-01

    Widely used electron accelerators in industries are the electron beams with acceleration voltage at 300 kV or less. The typical examples are shown on manufactures in Japan, equipment configuration, operation, determination of process parameters, and basic maintenance requirement of the electron beam processors. New electron beam processors with acceleration voltage around 100 kV were introduced maintaining the relatively high dose speed capability of around 10,000 kGy x mpm at production by ESI (Energy Science Inc. USA, Iwasaki Electric Group). The application field like printing and coating for packaging requires treating thickness of 30 micron or less. It does not require high voltage over 110 kV. Also recently developed is a miniature bulb type electron beam tube with energy less than 60 kV. The new application area for this new electron beam tube is being searched. The drive force of this technology to spread in the industries would be further development of new application, process and market as well as the price reduction of the equipment, upon which further acknowledgement and acceptance of the technology to societies and industries would entirely depend. (Y. Tanaka)

  5. San Francisco Accelerator Conference

    'Where are today's challenges in accelerator physics?' was the theme of the open session at the San Francisco meeting, the largest ever gathering of accelerator physicists and engineers

  6. Dielectric Laser Acceleration

    England, R. Joel; Noble, Robert J.; Wu, Ziran; Qi, Minghao

    2013-01-01

    We describe recent advances in the study of particle acceleration using dielectric near-field structures driven by infrared lasers, which we refer to as Dielectric Laser Accelerators. Implications for high energy physics and other applications are discussed.

  7. Standing wave linear accelerator

    Consideration is being given to standing wave linear accelerator containing generator, phase shifter, two accelerating resonator sections, charged particle injector and waveguide bridge. Its first arm is oined up with generator via the phase shifter, the second and the third ones-with accelerating sections and the fourth one - with HF-power absorber. HF-power absorber represents a section of circular diaphragmatic wavequide with transformer with input wave and intrawaveguide output load located between injector and the first accelerating section. The section possesses holes in side walls lying on accelerator axis. The distances between centers of the last cell of the fast accelerating section and the first cell of the second accelerating sectiOn equal (2n+3)lambda/4, where n=1, 2, 3..., lambda - wave length of generator. The suggested system enables to improve by one order spectral characteristics of accelerators as compared to the prototype in which magnetrons are used as generator

  8. Improved plasma accelerator

    Cheng, D. Y.

    1971-01-01

    Converging, coaxial accelerator electrode configuration operates in vacuum as plasma gun. Plasma forms by periodic injections of high pressure gas that is ionized by electrical discharges. Deflagration mode of discharge provides acceleration, and converging contours of plasma gun provide focusing.

  9. High Energy Particle Accelerators

    Audio Productions, Inc, New York

    1960-01-01

    Film about the different particle accelerators in the US. Nuclear research in the US has developed into a broad and well-balanced program.Tour of accelerator installations, accelerator development work now in progress and a number of typical experiments with high energy particles. Brookhaven, Cosmotron. Univ. Calif. Berkeley, Bevatron. Anti-proton experiment. Negative k meson experiment. Bubble chambers. A section on an electron accelerator. Projection of new accelerators. Princeton/Penn. build proton synchrotron. Argonne National Lab. Brookhaven, PS construction. Cambridge Electron Accelerator; Harvard/MIT. SLAC studying a linear accelerator. Other research at Madison, Wisconsin, Fixed Field Alternate Gradient Focusing. (FFAG) Oakridge, Tenn., cyclotron. Two-beam machine. Comments : Interesting overview of high energy particle accelerators installations in the US in these early years. .

  10. Turning Search into Knowledge Management.

    Kaufman, David

    2002-01-01

    Discussion of knowledge management for electronic data focuses on creating a high quality similarity ranking algorithm. Topics include similarity ranking and unstructured data management; searching, categorization, and summarization of documents; query evaluation; considering sentences in addition to keywords; and vector models. (LRW)

  11. Self-similar blast waves incorporating deflagrations of variable speed

    Guirguis, R. H.; Kamel, M. M.; Oppenheim, A. K.

    1983-01-01

    The present investigation is concerned with the development of a systematic approach to the problem of self-similar blast waves incorporating nonsteady flames. The regime covered by the presented solutions is bounded on one side by an adiabatic strong explosion and, on the other, by deflagration propagating at an infinite acceleration. Results for a representative set of accelerations are displayed, taking into account the full range of propagation speeds from zero to velocities corresponding to the Chapman-Jouguet deflagration. It is found that the distribution of stored energy in the undisturbed medium determines the acceleration of the deflagration-shock wave system. The obtained results reveal the existence of a simple relation between the location of the deflagration and its Mach number.

  12. Maximal Acceleration Is Nonrotating

    Page, Don N.

    1997-01-01

    In a stationary axisymmetric spacetime, the angular velocity of a stationary observer that Fermi-Walker transports its acceleration vector is also the angular velocity that locally extremizes the magnitude of the acceleration of such an observer, and conversely if the spacetime is also symmetric under reversing both t and phi together. Thus a congruence of Nonrotating Acceleration Worldlines (NAW) is equivalent to a Stationary Congruence Accelerating Locally Extremely (SCALE). These congruenc...

  13. Accelerators at school

    Latest subject covered by the CERN Accelerator School was 'Applied Geodesy of Particle Accelerators', which attracted an impressive number of outside participants to CERN for a week in April. Since the forerunners of today's particle accelerators were demonstrated over 50 years ago, the positioning of accelerator components has progressed from the laboratory bench-top to tunnels tens of kilometres long. Despite this phenomenal growth in size, sub-millimetre accuracy is still required

  14. A Solid state accelerator

    We present a solid state accelerator concept utilizing particle acceleration along crystal channels by longitudinal electron plasma waves in a metal. Acceleration gradients of order 100 GV/cm are theoretically possible, but channeling radiation limits the maximum attainable energy to 105 TeV for protons. Beam dechanneling due to multiple scattering is substantially reduced by the high acceleration gradient. Plasma wave dissipation and generation in metals are also discussed

  15. Superconducting accelerator technology

    Modern and future accelerators for high energy and nuclear physics rely increasingly on superconducting components to achieve the required magnetic fields and accelerating fields. This paper presents a practical overview of the phenomenon of superconductivity, and describes the design issues and solutions associated with superconducting magnets and superconducting rf acceleration structures. Further development and application of superconducting components promises increased accelerator performance at reduced electric power cost

  16. Applications of particle accelerators

    Particle accelerators are now widely used in a variety of applications for scientific research, applied physics, medicine, industrial processing, while possible utilisation in power engineering is envisaged. Earlier presentations of this subject, given at previous CERN Accelerator School sessions have been updated with papers contributed to the first European Conference on Accelerators in Applied Research and Technology (ECAART) held in September 1989 in Frankfurt and to the Second European Particle Accelerator Conference in Nice in June 1990. (orig.)

  17. Accelerator development in BARC

    Charged particle accelerators have played crucial role in the field of both basic and applied sciences. This has been possible because the accelerators have been extensively utilized from unraveling the secrets of nature to diverse applications such as implantation, material modification, medical diagnostics and therapy, nuclear energy and clean air and water. The development of accelerators in BARC can be categorized in two broad categories namely proton and heavy ion based accelerators and electron based accelerators. The heavy ion accelerators with sufficiently high energies are currently being used for conducting frontline nuclear and allied research whereas the electron accelerators are being routinely used for various industrial applications. Recently, there is a strong interest for developing the high energy and high intensity accelerators due to their possibility of effective utilization towards concept of energy amplification (Accelerator Driven System), incineration nuclear waste and transmutation. This talk will discuss details of the accelerator development program in BARC with particular emphasis on the recent development at Low Energy High Intensity Proton Accelerator (LEHIPA) Facility in Ion Accelerator Development Division, BARC. (author)

  18. Far field acceleration

    Far fields are propagating electromagnetic waves far from their source, boundary surfaces, and free charges. The general principles governing the acceleration of charged particles by far fields are reviewed. A survey of proposed field configurations is given. The two most important schemes, Inverse Cerenkov acceleration and Inverse free electron laser acceleration, are discussed in detail

  19. The CERN Accelerator School

    2016-01-01

    Introduction to accelerator physics The CERN Accelerator School: Introduction to Accelerator Physics, which should have taken place in Istanbul, Turkey, later this year has now been relocated to Budapest, Hungary.  Further details regarding the new hotel and dates will be made available as soon as possible on a new Indico site at the end of May.

  20. Acceleration: It's Elementary

    Willis, Mariam

    2012-01-01

    Acceleration is one tool for providing high-ability students the opportunity to learn something new every day. Some people talk about acceleration as taking a student out of step. In actuality, what one is doing is putting a student in step with the right curriculum. Whole-grade acceleration, also called grade-skipping, usually happens between…

  1. On the structure of acceleration in turbulence

    Liberzon, A.; Lüthi, B.; Holzner, M.; Ott, Søren; Berg, Jacob; Mann, Jakob

    2012-01-01

    Acceleration and spatial velocity gradients are obtained simultaneously in an isotropic turbulent flow via three dimensional particle tracking velocimetry. We observe two distinct populations of intense acceleration events: one in flow regions of strong strain and another in regions of strong...... vorticity. Geometrical alignments with respect to vorticity vector and to the strain eigenvectors, curvature of Lagrangian trajectories and of streamlines for total acceleration, and for its convective part, , are studied in detail. We discriminate the alignment features of total and convective acceleration...... statistics, which are genuine features of turbulent nature from those of kinematic nature. We find pronounced alignment of acceleration with vorticity. Similarly, and especially are predominantly aligned at 45°with the most stretching and compressing eigenvectors of the rate of the strain tensor, , and...

  2. Mechanisms for similarity based cooperation

    Traulsen, A.

    2008-06-01

    Cooperation based on similarity has been discussed since Richard Dawkins introduced the term “green beard” effect. In these models, individuals cooperate based on an aribtrary signal (or tag) such as the famous green beard. Here, two different models for such tag based cooperation are analysed. As neutral drift is important in both models, a finite population framework is applied. The first model, which we term “cooperative tags” considers a situation in which groups of cooperators are formed by some joint signal. Defectors adopting the signal and exploiting the group can lead to a breakdown of cooperation. In this case, conditions are derived under which the average abundance of the more cooperative strategy exceeds 50%. The second model considers a situation in which individuals start defecting towards others that are not similar to them. This situation is termed “defective tags”. It is shown that in this case, individuals using tags to cooperate exclusively with their own kind dominate over unconditional cooperators.

  3. Internet Search Engines

    Fatmaa El Zahraa Mohamed Abdou

    2004-01-01

    A general study about the internet search engines, the study deals main 7 points; the differance between search engines and search directories, components of search engines, the percentage of sites covered by search engines, cataloging of sites, the needed time for sites appearance in search engines, search capabilities, and types of search engines.

  4. Internet Search Engines

    Fatmaa El Zahraa Mohamed Abdou

    2004-09-01

    Full Text Available A general study about the internet search engines, the study deals main 7 points; the differance between search engines and search directories, components of search engines, the percentage of sites covered by search engines, cataloging of sites, the needed time for sites appearance in search engines, search capabilities, and types of search engines.

  5. The Accelerator Reliability Forum

    Lüdeke, Andreas; Giachino, R

    2014-01-01

    A high reliability is a very important goal for most particle accelerators. The biennial Accelerator Reliability Workshop covers topics related to the design and operation of particle accelerators with a high reliability. In order to optimize the over-all reliability of an accelerator one needs to gather information on the reliability of many different subsystems. While a biennial workshop can serve as a platform for the exchange of such information, the authors aimed to provide a further channel to allow for a more timely communication: the Particle Accelerator Reliability Forum [1]. This contribution will describe the forum and advertise it’s usage in the community.

  6. Direct Laser Acceleration in Laser Wakefield Accelerators

    Shaw, Jessica

    2016-01-01

    In this dissertation, the direct laser acceleration (DLA) of ionization-injected electrons in a laser wakefield accelerator (LWFA) operating in the quasi-blowout regime has been investigated through experiment and simulation. In the blowout regime of LWFA, the radiation pressure of an intense laser pulse can push a majority of the plasma electrons out and around the main body of the pulse. The expelled plasma electrons feel the electrostatic field of the relatively-stationary ions and are t...

  7. Next linear collider test accelerator injector upgrade

    Yeremian, A.D.; Miller, R.H. [Stanford Linear Accelerator Center, CA (United States)

    1995-12-31

    The Next Linear Collider Test Accelerator (NLCTA) is being constructed at SLAC to demonstrate multibunch beam loading compensation, suppression of higher order deflecting modes and measure transverse components of the accelerating fields in X-band accelerating structures. Currently a simple injector which provides the average current necessary for the beam loading compensations studies is under construction. An injector upgrade is planned to produce bunch trains similar to that of the NLC with microbunch intensity, separation and energy spread, identical to that of NLC. We discuss the design of the NLCTA injector upgrade.

  8. Personnel hazards from medical electron accelerator photoneutrons

    For medical accelerators, neutron penetration through the room entry door is the major personnel hazard. Most therapy accelerator rooms are designed with at least a rudimentary maze to avoid the use of massive doors. Often, however, the maze may be similar to those shown in scale outline drawings of some medical electron accelerator rooms where the authors have made neutron measurements outside the doors which were of different thicknesses and compositions. The results are tabulated. It should be noted that there can be significant dose equivalents (H) at the door when a maze is inadequate, and that all three components - fast neutron, thermal neutron, and neutron capture γ rays - can be equally important

  9. Calculation of tolerances in accelerating structures

    A method is suggested for calculating tolerances for similar elements of an accelerating-focusing channel of a charged particle linac the particle dynamics in which is described by linear or non-linear equations. Tolerances for each drift tube of the accelerating structure with modified variable-phase focusing are determined with respect to tolerances for the output parameters of an accelerated beam at preset lengths of drift tubes. The tolerances obtained in supposition of equal effects, equal tolerances and those accounting for the cost of fabrication and assembling of the elements of the structure are compared. The algorithm suggested can also be used for calculating tolerances in structures with hard focusing

  10. MINOS Sterile Neutrino Search

    Koskinen, David Jason [Univ. College London, Bloomsbury (United Kingdom)

    2009-02-01

    The Main Injector Neutrino Oscillation Search (MINOS) is a long-baseline accelerator neutrino experiment designed to measure properties of neutrino oscillation. Using a high intensity muon neutrino beam, produced by the Neutrinos at Main Injector (NuMI) complex at Fermilab, MINOS makes two measurements of neutrino interactions. The first measurement is made using the Near Detector situated at Fermilab and the second is made using the Far Detector located in the Soudan Underground laboratory in northern Minnesota. The primary goal of MINOS is to verify, and measure the properties of, neutrino oscillation between the two detectors using the v μ→ Vτ transition. A complementary measurement can be made to search for the existence of sterile neutrinos; an oft theorized, but experimentally unvalidated particle. The following thesis will show the results of a sterile neutrino search using MINOS RunI and RunII data totaling ~2.5 x 1020 protons on target. Due to the theoretical nature of sterile neutrinos, complete formalism that covers transition probabilities for the three known active states with the addition of a sterile state is also presented.

  11. MINOS Sterile Neutrino Search

    Koskinen, David Jason; /University Coll. London

    2009-09-01

    The Main Injector Neutrino Oscillation Search (MINOS) is a long-baseline accelerator neutrino experiment designed to measure properties of neutrino oscillation. Using a high intensity muon neutrino beam, produced by the Neutrinos at Main Injector (NuMI) complex at Fermilab, MINOS makes two measurements of neutrino interactions. The first measurement is made using the Near Detector situated at Fermilab and the second is made using the Far Detector located in the Soudan Underground laboratory in northern Minnesota. The primary goal of MINOS is to verify, and measure the properties of, neutrino oscillation between the two detectors using the {nu}{sub {mu}} {yields} V{sub {tau}} transition. A complementary measurement can be made to search for the existence of sterile neutrinos; an oft theorized, but experimentally unvalidated particle. The following thesis will show the results of a sterile neutrino search using MINOS RunI and RunII data totaling {approx}2.5 x 10{sup 20} protons on target. Due to the theoretical nature of sterile neutrinos, complete formalism that covers transition probabilities for the three known active states with the addition of a sterile state is also presented.

  12. Hot self-similar relativistic MHD flows

    Zakamska, Nadia L; Blandford, Roger D

    2008-01-01

    We consider axisymmetric relativistic jets with a toroidal magnetic field and an ultrarelativistic equation of state, with the goal of studying the lateral structure of jets whose pressure is matched to the pressure of the medium through which they propagate. We find all self-similar steady-state solutions of the relativistic MHD equations for this setup. One of the solutions is the case of a parabolic jet being accelerated by the pressure gradient as it propagates through a medium with pressure declining as p(z)\\propto z^{-2}. As the jet material expands due to internal pressure gradients, it runs into the ambient medium resulting in a pile-up of material along the jet boundary, while the magnetic field acts to produce a magnetic pinch along the axis of the jet. Such jets can be in a lateral pressure equilibrium only if their opening angle \\theta_j at distance z is smaller than about 1/\\gamma, where \\gamma is the characteristic bulk Lorentz-factor at this distance; otherwise, different parts of the jet canno...

  13. Performance Indexes: Similarities and Differences

    André Machado Caldeira

    2013-06-01

    Full Text Available The investor of today is more rigorous on monitoring a financial assets portfolio. He no longer thinks only in terms of the expected return (one dimension, but in terms of risk-return (two dimensions. Thus new perception is more complex, since the risk measurement can vary according to anyone’s perception; some use the standard deviation for that, others disagree with this measure by proposing others. In addition to this difficulty, there is the problem of how to consider these two dimensions. The objective of this essay is to study the main performance indexes through an empirical study in order to verify the differences and similarities for some of the selected assets. One performance index proposed in Caldeira (2005 shall be included in this analysis.

  14. Features Based Text Similarity Detection

    Kent, Chow Kok

    2010-01-01

    As the Internet help us cross cultural border by providing different information, plagiarism issue is bound to arise. As a result, plagiarism detection becomes more demanding in overcoming this issue. Different plagiarism detection tools have been developed based on various detection techniques. Nowadays, fingerprint matching technique plays an important role in those detection tools. However, in handling some large content articles, there are some weaknesses in fingerprint matching technique especially in space and time consumption issue. In this paper, we propose a new approach to detect plagiarism which integrates the use of fingerprint matching technique with four key features to assist in the detection process. These proposed features are capable to choose the main point or key sentence in the articles to be compared. Those selected sentence will be undergo the fingerprint matching process in order to detect the similarity between the sentences. Hence, time and space usage for the comparison process is r...

  15. Arabic Stemmer for Search Engines Information Retrieval

    Ahmed Khalid

    2016-01-01

    Full Text Available Arabic language is very different and difficult structure than other languages, that’s because it is a very rich language with complex morphology. Many stemmers have been developed for Arabic language but still there are many weakness and problems. There is still lack of usage of Arabic stemming in search engines. This paper introduces a rooted word Arabic stemmer technique. The results of the introduced technique for six Arabic sentences are used in famous search engines Google Chrome, Internet Explore and Mozilla Firefox to check the effect of using Arabic stemming in these search engines in terms of the total number of searched pages and the search time ratio for actual sentences and their stemming results. The results show that Arabic words stemming increase and accelerate the search engines output.

  16. A similarity-based data warehousing environment for medical images.

    Teixeira, Jefferson William; Annibal, Luana Peixoto; Felipe, Joaquim Cezar; Ciferri, Ricardo Rodrigues; Ciferri, Cristina Dutra de Aguiar

    2015-11-01

    A core issue of the decision-making process in the medical field is to support the execution of analytical (OLAP) similarity queries over images in data warehousing environments. In this paper, we focus on this issue. We propose imageDWE, a non-conventional data warehousing environment that enables the storage of intrinsic features taken from medical images in a data warehouse and supports OLAP similarity queries over them. To comply with this goal, we introduce the concept of perceptual layer, which is an abstraction used to represent an image dataset according to a given feature descriptor in order to enable similarity search. Based on this concept, we propose the imageDW, an extended data warehouse with dimension tables specifically designed to support one or more perceptual layers. We also detail how to build an imageDW and how to load image data into it. Furthermore, we show how to process OLAP similarity queries composed of a conventional predicate and a similarity search predicate that encompasses the specification of one or more perceptual layers. Moreover, we introduce an index technique to improve the OLAP query processing over images. We carried out performance tests over a data warehouse environment that consolidated medical images from exams of several modalities. The results demonstrated the feasibility and efficiency of our proposed imageDWE to manage images and to process OLAP similarity queries. The results also demonstrated that the use of the proposed index technique guaranteed a great improvement in query processing. PMID:26414378

  17. The future of particle accelerators

    Plasma-based accelerators are developing as credible, and compact, accelerators for the future. We review the status and prospects for electron and proton accelerators using laser Wakefield acceleration. (author)

  18. Interdisciplinary glossary — particle accelerators and medicine

    Dmitrieva, V. V.; Dyubkov, V. S.; Nikitaev, V. G.; Ulin, S. E.

    2016-02-01

    A general concept of a new interdisciplinary glossary, which includes particle accelerator terminology used in medicine, as well as relevant medical concepts, is presented. Its structure and usage rules are described. An example, illustrating the quickly searching technique of relevant information in this Glossary, is considered. A website address, where one can get an access to the Glossary, is specified. Glossary can be refined and supplemented.

  19. CASE in CERN's accelerator sector

    As in the software industry where computer aided software engineering (CASE) methodologies and tools are commonly used, CERN endeavours to introduce this technology to improve the efficiency of designing, producing and maintaining software. A large project is currently under development in the administrative area whereas a dedicated group had been set up to evaluate state of the art techniques for software development relating to physics experiments. A similar activity, though on a smaller scale, has been initiated in the accelerator sector also in view of the large amount of software that will be required by the LEP200 and the LHC projects. This paper briefly describes this technology and gives an account of current experience with the use of CASE methods and tools for technical projects in the accelerator sector at CERN. (author)

  20. Alaska, Gulf spills share similarities

    The accidental Exxon Valdez oil spill in Alaska and the deliberate dumping of crude oil into the Persian Gulf as a tactic of war contain both glaring differences and surprising similarities. Public reaction and public response was much greater to the Exxon Valdez spill in pristine Prince William Sound than to the war-related tragedy in the Persian Gulf. More than 12,000 workers helped in the Alaskan cleanup; only 350 have been involved in Kuwait. But in both instances, environmental damages appear to be less than anticipated. Natures highly effective self-cleansing action is primarily responsible for minimizing the damages. One positive action growing out of the two incidents is increased international cooperation and participation in oil-spill clean-up efforts. In 1990, in the aftermath of the Exxon Valdez spill, 94 nations signed an international accord on cooperation in future spills. The spills can be historic environmental landmarks leading to creation of more sophisticated response systems worldwide

  1. Relativistic Self-similar Disks

    Cai, M J; Cai, Mike J.; Shu, Frank H.

    2002-01-01

    We formulate and solve by semi-analytic means the axisymmetric equilibria of relativistic self-similar disks of infinitesimal vertical thickness. These disks are supported in the horizontal directions against their self-gravity by a combination of isothermal (two-dimensional) pressure and a flat rotation curve. The dragging of inertial frames restricts possible solutions to rotation speeds that are always less than 0.438 times the speed of light, a result first obtained by Lynden-Bell and Pineault in 1978 for a cold disk. We show that prograde circular orbits of massive test particles exist and are stable for all of our model disks, but retrograde circular orbits cannot be maintained with particle velocities less than the speed of light once the disk develops an ergoregion. We also compute photon trajectories, planar and non-planar, in the resulting spacetime, for disks with and without ergoregions. We find that all photon orbits, except for a set of measure zero, tend to be focused by the gravity of the flat...

  2. Particle-accelerator decommissioning

    Generic considerations involved in decommissioning particle accelerators are examined. There are presently several hundred accelerators operating in the United States that can produce material containing nonnegligible residual radioactivity. Residual radioactivity after final shutdown is generally short-lived induced activity and is localized in hot spots around the beam line. The decommissioning options addressed are mothballing, entombment, dismantlement with interim storage, and dismantlement with disposal. The recycle of components or entire accelerators following dismantlement is a definite possibility and has occurred in the past. Accelerator components can be recycled either immediately at accelerator shutdown or following a period of storage, depending on the nature of induced activation. Considerations of cost, radioactive waste, and radiological health are presented for four prototypic accelerators. Prototypes considered range from small accelerators having minimal amounts of radioactive mmaterial to a very large accelerator having massive components containing nonnegligible amounts of induced activation. Archival information on past decommissionings is presented, and recommendations concerning regulations and accelerator design that will aid in the decommissioning of an accelerator are given

  3. An introduction to acceleration mechanisms

    This paper discusses the acceleration of charged particles by electromagnetic fields, i.e., by fields that are produced by the motion of other charged particles driven by some power source. The mechanisms that are discussed include: Ponderamotive Forces, Acceleration, Plasma Beat Wave Acceleration, Inverse Free Electron Laser Acceleration, Inverse Cerenkov Acceleration, Gravity Acceleration, 2D Linac Acceleration and Conventional Iris Loaded Linac Structure Acceleration

  4. Accelerated convergence and robust asymptotic regression of the Gumbel scale parameter for gapped sequence alignment

    Searches through biological databases provide the primary motivation for studying sequence alignment statistics. Other motivations include physical models of annealing processes or mathematical similarities to, e.g., first-passage percolation and interacting particle systems. Here, we investigate sequence alignment statistics, partly to explore two general mathematical methods. First, we model the global alignment of random sequences heuristically with Markov additive processes. In sequence alignment, the heuristic suggests a numerical acceleration scheme for simulating an important asymptotic parameter (the Gumbel scale parameter λ). The heuristic might apply to similar mathematical theories. Second, we extract the asymptotic parameter λ from simulation data with the statistical technique of robust regression. Robust regression is admirably suited to 'asymptotic regression' and deserves to be better known for it

  5. Brazing techniques for side-coupled electron accelerator structures

    The collaboration between the Los Alamos National Laboratory and the National Bureau of Standards (NBS), started in 1979, has led to the development of an advanced c-w microtron accelerator design. The four 2380-MHz NBS accelerating structures, containing a total of 184 accelerating cavities, have been fabricated and delivered. New fabrication methods, coupled with refinements of hydrogen-furnace brazing techniques described in this paper, allow efficient production of side-coupled structures. Success with the NBS RTM led to Los Alamos efforts on similar 2450-MHz accelerators for the microtron accelerator operated by the Nuclear Physics Department of the University of Illinois. Two accelerators (each with 17 cavities) have been fabricated; in 1986, a 45-cavity accelerator is being fabricated by private industry with some assistance from Los Alamos. Further private industry experience and refinement of the described fabrication techniques may allow future accelerators of this type to be completely fabricated by private industry

  6. A New Generalized Similarity-Based Topic Distillation Algorithm

    ZHOU Hongfang; DANG Xiaohui

    2007-01-01

    The procedure of hypertext induced topic search based on a semantic relation model is analyzed, and the reason for the topic drift of HITS algorithm was found to prove that Web pages are projected to a wrong latent semantic basis. A new concept-generalized similarity is introduced and, based on this, a new topic distillation algorithm GSTDA(generalized similarity based topic distillation algorithm) was presented to improve the quality of topic distillation. GSTDA was applied not only to avoid the topic drift, but also to explore relative topics to user query. The experimental results on 10 queries show that GSTDA reduces topic drift rate by 10% to 58% compared to that of HITS(hypertext induced topic search) algorithm, and discovers several relative topics to queries that have multiple meanings.

  7. Positive selection, relaxation, and acceleration in the evolution of the human and chimp genome.

    Leonardo Arbiza

    2006-04-01

    Full Text Available For years evolutionary biologists have been interested in searching for the genetic bases underlying humanness. Recent efforts at a large or a complete genomic scale have been conducted to search for positively selected genes in human and in chimp. However, recently developed methods allowing for a more sensitive and controlled approach in the detection of positive selection can be employed. Here, using 13,198 genes, we have deduced the sets of genes involved in rate acceleration, positive selection, and relaxation of selective constraints in human, in chimp, and in their ancestral lineage since the divergence from murids. Significant deviations from the strict molecular clock were observed in 469 human and in 651 chimp genes. The more stringent branch-site test of positive selection detected 108 human and 577 chimp positively selected genes. An important proportion of the positively selected genes did not show a significant acceleration in rates, and similarly, many of the accelerated genes did not show significant signals of positive selection. Functional differentiation of genes under rate acceleration, positive selection, and relaxation was not statistically significant between human and chimp with the exception of terms related to G-protein coupled receptors and sensory perception. Both of these were over-represented under relaxation in human in relation to chimp. Comparing differences between derived and ancestral lineages, a more conspicuous change in trends seems to have favored positive selection in the human lineage. Since most of the positively selected genes are different under the same functional categories between these species, we suggest that the individual roles of the alternative positively selected genes may be an important factor underlying biological differences between these species.

  8. Accelerator and radiation physics

    Basu, Samita; Nandy, Maitreyee

    2013-01-01

    "Accelerator and radiation physics" encompasses radiation shielding design and strategies for hadron therapy accelerators, neutron facilities and laser based accelerators. A fascinating article describes detailed transport theory and its application to radiation transport. Detailed information on planning and design of a very high energy proton accelerator can be obtained from the article on radiological safety of J-PARC. Besides safety for proton accelerators, the book provides information on radiological safety issues for electron synchrotron and prevention and preparedness for radiological emergencies. Different methods for neutron dosimetry including LET based monitoring, time of flight spectrometry, track detectors are documented alongwith newly measured experimental data on radiation interaction with dyes, polymers, bones and other materials. Design of deuteron accelerator, shielding in beam line hutches in synchrotron and 14 MeV neutron generator, various radiation detection methods, their characteriza...

  9. Leaky Fermi accelerators

    Shah, Kushal; Rom-Kedar, Vered; Turaev, Dmitry

    2015-01-01

    A Fermi accelerator is a billiard with oscillating walls. A leaky accelerator interacts with an environment of an ideal gas at equilibrium by exchange of particles through a small hole on its boundary. Such interaction may heat the gas: we estimate the net energy flow through the hole under the assumption that the particles inside the billiard do not collide with each other and remain in the accelerator for sufficiently long time. The heat production is found to depend strongly on the type of the Fermi accelerator. An ergodic accelerator, i.e. one which has a single ergodic component, produces a weaker energy flow than a multi-component accelerator. Specifically, in the ergodic case the energy gain is independent of the hole size, whereas in the multi-component case the energy flow may be significantly increased by shrinking the hole size.

  10. Accelerator reliability workshop

    Hardy, L.; Duru, Ph.; Koch, J.M.; Revol, J.L.; Van Vaerenbergh, P.; Volpe, A.M.; Clugnet, K.; Dely, A.; Goodhew, D

    2002-07-01

    About 80 experts attended this workshop, which brought together all accelerator communities: accelerator driven systems, X-ray sources, medical and industrial accelerators, spallation sources projects (American and European), nuclear physics, etc. With newly proposed accelerator applications such as nuclear waste transmutation, replacement of nuclear power plants and others. Reliability has now become a number one priority for accelerator designers. Every part of an accelerator facility from cryogenic systems to data storage via RF systems are concerned by reliability. This aspect is now taken into account in the design/budget phase, especially for projects whose goal is to reach no more than 10 interruptions per year. This document gathers the slides but not the proceedings of the workshop.

  11. Nuclear physics accelerator facilities

    This paper describes many of the nuclear physics heavy-ion accelerator facilities in the US and the research programs being conducted. The accelerators described are: Argonne National Laboratory--ATLAS; Brookhaven National Laboratory--Tandem/AGS Heavy Ion Facility; Brookhaven National Laboratory--Relativistic Heavy Ion Collider (RHIC) (Proposed); Continuous Electron Beam Accelerator Facility; Lawrence Berkeley Laboratory--Bevalac; Lawrence Berkeley Laboratory--88-Inch Cyclotron; Los Alamos National Laboratory--Clinton P. Anderson Meson Physics Facility (LAMPF); Massachusetts Institute of Technology--Bates Linear Accelerator Center; Oak Ridge National Laboratory--Holifield Heavy Ion Research Facility; Oak Ridge National Laboratory--Oak Ridge Electron Linear Accelerator; Stanford Linear Accelerator Center--Nuclear Physics Injector; Texas AandM University--Texas AandM Cyclotron; Triangle Universities Nuclear Laboratory (TUNL); University of Washington--Tandem/Superconducting Booster; and Yale University--Tandem Van de Graaff

  12. Accelerator reliability workshop

    About 80 experts attended this workshop, which brought together all accelerator communities: accelerator driven systems, X-ray sources, medical and industrial accelerators, spallation sources projects (American and European), nuclear physics, etc. With newly proposed accelerator applications such as nuclear waste transmutation, replacement of nuclear power plants and others. Reliability has now become a number one priority for accelerator designers. Every part of an accelerator facility from cryogenic systems to data storage via RF systems are concerned by reliability. This aspect is now taken into account in the design/budget phase, especially for projects whose goal is to reach no more than 10 interruptions per year. This document gathers the slides but not the proceedings of the workshop

  13. Switched Matrix Accelerator

    We describe a new concept for a microwave circuit functioning as a charged-particle accelerator at mm-wavelengths, permitting an accelerating gradient higher than conventional passive circuits can withstand consistent with cyclic fatigue. The device provides acceleration for multiple bunches in parallel channels, and permits a short exposure time for the conducting surface of the accelerating cavities. Our analysis includes scalings based on a smooth transmission line model and a complementary treatment with a coupled-cavity simulation. We provide also an electromagnetic design for the accelerating structure, arriving at rough dimensions for a seven-cell accelerator matched to standard waveguide and suitable for bench tests at low power in air at 91.392. GHz. A critical element in the concept is a fast mm-wave switch suitable for operation at high-power, and we present the considerations for implementation in an H-plane tee. We discuss the use of diamond as the photoconductor switch medium

  14. Database automation of accelerator operation

    Database management techniques are applied to automating the setup of operating parameters of a heavy-ion accelerator used in nuclear physics experiments. Data files consist of ion-beam attributes, the interconnection assignments of the numerous power supplies and magnetic elements that steer the ions' path through the system, the data values that represent the electrical currents supplied by the power supplies, as well as the positions of motors and status of mechanical actuators. The database is relational and permits searching on ranges of any subset of the ion-beam attributes. A file selected from the database is used by the control software to replicate the ion beam conditions by adjusting the physical elements in a continuous manner

  15. An assessment of orthographic similarity measures for several African languages

    Keet, C. Maria

    2016-01-01

    Natural Language Interfaces and tools such as spellcheckers and Web search in one's own language are known to be useful in ICT-mediated communication. Most languages in Southern Africa are under-resourced, however. Therefore, it would be very useful if both the generic and the few language-specific NLP tools could be reused or easily adapted across languages. This depends on the notion, and extent, of similarity between the languages. We assess this from the angle of orthography and corpora. ...

  16. Fundamentals of database indexing and searching

    Bhattacharya, Arnab

    2014-01-01

    Fundamentals of Database Indexing and Searching presents well-known database searching and indexing techniques. It focuses on similarity search queries, showing how to use distance functions to measure the notion of dissimilarity.After defining database queries and similarity search queries, the book organizes the most common and representative index structures according to their characteristics. The author first describes low-dimensional index structures, memory-based index structures, and hierarchical disk-based index structures. He then outlines useful distance measures and index structures

  17. CAS - CERN Accelerator School: RF for Accelerators

    2012-01-01

    These proceedings present the lectures given at the twenty-fourth specialized course organized by the CERN Accelerator School (CAS). The course was held in Ebeltoft, Denmark, from 8-17 June, 2010 in collaboration with Aarhus University, with the topic 'RF for Accelerators' While this topic has been covered by CAS previously, early in the 1990s and again in 2000, it was recognized that recent advances in the field warranted an updated course. Following introductory courses covering the background physics, the course attempted to cover all aspects of RF for accelerators; from RF power generation and transport, through cavity and coupler design, electronics and low level control, to beam diagnostics and RF gymnastics. The lectures were supplemented with several sessions of exercises, which were completed by discussion sessions on the solutions.

  18. Accelerator shielding benchmark problems

    Accelerator shielding benchmark problems prepared by Working Group of Accelerator Shielding in the Research Committee on Radiation Behavior in the Atomic Energy Society of Japan were compiled by Radiation Safety Control Center of National Laboratory for High Energy Physics. Twenty-five accelerator shielding benchmark problems are presented for evaluating the calculational algorithm, the accuracy of computer codes and the nuclear data used in codes. (author)

  19. Accelerator shielding benchmark problems

    Hirayama, H.; Ban, S.; Nakamura, T. [and others

    1993-01-01

    Accelerator shielding benchmark problems prepared by Working Group of Accelerator Shielding in the Research Committee on Radiation Behavior in the Atomic Energy Society of Japan were compiled by Radiation Safety Control Center of National Laboratory for High Energy Physics. Twenty-five accelerator shielding benchmark problems are presented for evaluating the calculational algorithm, the accuracy of computer codes and the nuclear data used in codes. (author).

  20. The foxhole accelerating structure

    This report examines some properties of a new type of open accelerating structure. It consists of a series of rectangular cavities, which we call foxholes, joined by a beam channel. The power for accelerating the particles comes from an external radiation source and enters the cavities through their open upper surfaces. Analytic and computer calculations are presented showing that the foxhole is a suitable structure for accelerating relativistic electrons

  1. Japan Accelerator Conference

    At the international level, the high energy accelerator scene evolves rapidly and the International Conference on High Energy Accelerators is where its strong pulse can best be felt. This year, the Conference was held for the first time in Japan, with the 14th meeting in the series having been hosted in August by the Japanese KEK National Laboratory for High Energy Physics, Tsukuba. The venue was a recognition of the premier accelerator physics and technology status achieved by this diligent nation

  2. A study of Consistency in the Selection of Search Terms and Search Concepts: A Case Study in National Taiwan University

    Mu-hsuan Huang

    2001-12-01

    Full Text Available This article analyzes the consistency in the selection of search terms and search contents of college and graduate students in National Taiwan University when they are using PsycLIT CD-ROM database. 31 students conducted pre-assigned searches, doing 59 searches generating 609 search terms. The study finds the consistency in selection of search terms of first level is 22.14% and second level is 35%. These results are similar with others’ researches. About the consistency in search concepts, no matter the overlaps of searched articles or judge relevant articles are lower than other researches. [Article content in Chinese

  3. Superconducting accelerator magnets

    In the near future, a large number of high quality superconducting dipole and quadrupole magnets will be required for construction of the next generation multi-TeV high energy hadron accelerator-colliders. To establish the construction technology of such accelerator- colliders, extensive and world-wide R and D programs are now carrying out at several laboratories. In this paper the important issues in superconducting accelerator magnets such as cables, design, fabrication, testing and cryogenic system are discussed together with some details on coil cross- sectional current configurations, quality control of materials, quench protections, radiation heating and etc. The key technology in superconducting accelerator magnets is summarized

  4. High Gradient Accelerator Research

    Temkin, Richard [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States). Dept. of Physics. Plasma Science and Fusion Center

    2016-07-12

    The goal of the MIT program of research on high gradient acceleration is the development of advanced acceleration concepts that lead to a practical and affordable next generation linear collider at the TeV energy level. Other applications, which are more near-term, include accelerators for materials processing; medicine; defense; mining; security; and inspection. The specific goals of the MIT program are: • Pioneering theoretical research on advanced structures for high gradient acceleration, including photonic structures and metamaterial structures; evaluation of the wakefields in these advanced structures • Experimental research to demonstrate the properties of advanced structures both in low-power microwave cold test and high-power, high-gradient test at megawatt power levels • Experimental research on microwave breakdown at high gradient including studies of breakdown phenomena induced by RF electric fields and RF magnetic fields; development of new diagnostics of the breakdown process • Theoretical research on the physics and engineering features of RF vacuum breakdown • Maintaining and improving the Haimson / MIT 17 GHz accelerator, the highest frequency operational accelerator in the world, a unique facility for accelerator research • Providing the Haimson / MIT 17 GHz accelerator facility as a facility for outside users • Active participation in the US DOE program of High Gradient Collaboration, including joint work with SLAC and with Los Alamos National Laboratory; participation of MIT students in research at the national laboratories • Training the next generation of Ph. D. students in the field of accelerator physics.

  5. High-intensity accelerators

    The design of high-intensity accelerators is described, using examples of machines being built at the Los Alamos National Laboratory. The major design problem with these accelerators is associated with control of beam loss when accelerator intensity is increased. Beam dynamics, beam loss, and the radio-frequency quadrupole structure are discussed in the first part of the chapter followed by an explanation of plans to achieve high-intensity operation in three projects: the Fusion Material Irradiation Tests (a joint effort with the Hanford Development Laboratory in Richland, Washington), the Proton Storage Ring (an addition to the LAMPF accelerator), and the Racetrack Microtron Project

  6. Computer programs in accelerator physics

    Three areas of accelerator physics are discussed in which computer programs have been applied with much success: i) single-particle beam dynamics in circular machines, i.e. the design and matching of machine lattices; ii) computations of electromagnetic fields in RF cavities and similar objects, useful for the design of RF cavities and for the calculation of wake fields; iii) simulation of betatron and synchrotron oscillations in a machine with non-linear elements, e.g. sextupoles, and of bunch lengthening due to longitudinal wake fields. (orig.)

  7. JUELICH: COSY acceleration and cooling

    The COSY cooler synchrotron at the KFA Forschungszentrum Jülich, inaugurated on 1 April, is now well on its way towards precision-defined high energy beams to open new fields for Jülich physics experiments. In two important goals, on 25 May the first beam cooled by electrons circulated inside the accelerator, then on 25 July physicists succeeded in accelerating the beam from the 270 MeV/c injection momentum to 600 MeV. Shortly after, this was pushed well above 1 GeV. Throughout the tuning process the number of stored particles increased steadily, finally peaking at 1.1 x 1011, a value compatible with the predicted limit at the injection energy. This success was the result of a painstaking search for the optimum parameter set, the commissioning crew being acutely aware that bringing such a large machine on line was a major experiment in its own right. The 3.3 GeV/c COSY machine belongs to the new class of hadron storage and cooler synchrotrons which started with CERN's LEAR low energy antiproton ring. COSY will 'sharpen' its beams to a narrow momentum spread using both electron and stochastic cooling to control the circulating particles. In addition it will provide space for internal experiments. Both features will allow for novel experimental approaches, and more than 100 physicists are eagerly waiting for the first proton reactions in their detectors

  8. Numerical study of similarity in prototype and model pumped turbines

    Similarity study of prototype and model pumped turbines are performed by numerical simulation and the partial discharge case is analysed in detail. It is found out that in the RSI (rotor-stator interaction) region where the flow is convectively accelerated with minor flow separation, a high level of similarity in flow patterns and pressure fluctuation appear with relative pressure fluctuation amplitude of model turbine slightly higher than that of prototype turbine. As for the condition in the runner where the flow is convectively accelerated with severe separation, similarity fades substantially due to different topology of flow separation and vortex formation brought by distinctive Reynolds numbers of the two turbines. In the draft tube where the flow is diffusively decelerated, similarity becomes debilitated owing to different vortex rope formation impacted by Reynolds number. It is noted that the pressure fluctuation amplitude and characteristic frequency of model turbine are larger than those of prototype turbine. The differences in pressure fluctuation characteristics are discussed theoretically through dimensionless Navier-Stokes equation. The above conclusions are all made based on simulation without regard to the penstock response and resonance

  9. Angular velocities, angular accelerations, and coriolis accelerations

    Graybiel, A.

    1975-01-01

    Weightlessness, rotating environment, and mathematical analysis of Coriolis acceleration is described for man's biological effective force environments. Effects on the vestibular system are summarized, including the end organs, functional neurology, and input-output relations. Ground-based studies in preparation for space missions are examined, including functional tests, provocative tests, adaptive capacity tests, simulation studies, and antimotion sickness.

  10. Accelerator Modeling with MATLAB Accelerator Toolbox

    This paper introduces Accelerator Toolbox (AT)--a collection of tools to model storage rings and beam transport lines in the MATLAB environment. The objective is to illustrate the flexibility and efficiency of the AT-MATLAB framework. The paper discusses three examples of problems that are analyzed frequently in connection with ring-based synchrotron light sources

  11. Quantum search followed by classical search versus quantum search alone

    Sousa, P. R. M.; Mendes, F. V.; Ramos, R. V.

    2015-01-01

    In this work, we show that the usage of a quantum gate that gives extra information about the solution searched permits to improve the performance of the search algorithm by switching from quantum to classical search in the appropriated moment. A comparison to the case where only quantum search is used is also realized.

  12. Improved Scatter Search Using Cuckoo Search

    Ahmed T.Sadiq Al-Obaidi

    2013-01-01

    The Scatter Search (SS) is a deterministic strategy that has been applied successfully to some combinatorial and continuous optimization problems. Cuckoo Search (CS) is heuristic search algorithm which is inspired by the reproduction strategy of cuckoos. This paper presents enhanced scatter search algorithm using CS algorithm. The improvement provides Scatter Search with random exploration for search space of problem and more of diversity and intensification for promising solutions. The origi...

  13. Timescales for detecting a significant acceleration in sea level rise

    Haigh, Ivan D.; Wahl, Thomas; Rohling, Eelco J.; Price, René M.; Pattiaratchi, Charitha B.; Calafat, Francisco M.; Dangendorf, Sönke

    2014-01-01

    There is observational evidence that global sea level is rising and there is concern that the rate of rise will increase, significantly threatening coastal communities. However, considerable debate remains as to whether the rate of sea level rise is currently increasing and, if so, by how much. Here we provide new insights into sea level accelerations by applying the main methods that have been used previously to search for accelerations in historical data, to identify the timings (with uncer...

  14. Dynamic Spectrum Sensing Through Accelerated Particle Swarm Optimization

    Paschos, Alexandros E.; Kapinas, Vasileios M.; Hadjileontiadis, Leontios J.; Karagiannidis, George K.

    2015-01-01

    A novel optimization algorithm, called accelerated particle swarm optimization (APSO), is proposed for dynamic spectrum sensing in cognitive radio networks. While modified swarm-based optimization algorithms focus on slight variations of the standard mathematical formulas, in APSO, the acceleration variable of the particles in the swarm is also considered in the search space of the optimization problem. We show that the proposed APSO-based dynamic spectrum sensing technique is more efficient ...

  15. Status report on the University of Manitoba Accelerator Laboratory

    The University of Manitoba cyclotron completed an extensive upgrading program in late 1984. Since then, the cyclotron has operated very reliably and has realized the upgrading objectives for acceleration of H- ions. Future plans for upgrading and operation will be discussed. Recent trends in the funding of small accelerator laboratories have necessitated a search for financial support in fields not directly related to nuclear physics. Some facilities and services for use in these areas of research will be described. (author)

  16. Search for $\

    Astier, Pierre; Baldisseri, Alberto; Baldo-Ceolin, Massimilla; Banner, M; Bassompierre, Gabriel; Benslama, K; Besson, N; Bird, I; Blumenfeld, B; Bobisut, F; Bouchez, J; Boyd, S; Bueno, A G; Bunyatov, S; Camilleri, L L; Cardini, A; Cattaneo, Paolo Walter; Cavasinni, V; Cervera-Villanueva, A; Challis, R C; Chukanov, A; Collazuol, G; Conforto, G; Conta, C; Contalbrigo, M; Cousins, R; Daniels, D; Degaudenzi, H M; Del Prete, T; De Santo, A; Dignan, T; Di Lella, L; do Couto e Silva, E; Dumarchez, J; Ellis, M; Feldman, G J; Ferrari, R; Ferrère, D; Flaminio, Vincenzo; Fraternali, M; Gaillard, J M; Gangler, E; Geiser, A; Geppert, D; Gibin, D; Gninenko, S N; Godley, A; Gómez-Cadenas, J J; Gosset, J; Gössling, C; Gouanère, M; Grant, A; Graziani, G; Guglielmi, A M; Hagner, C; Hernando, J A; Hubbard, D B; Hurst, P; Hyett, N; Iacopini, E; Joseph, C L; Juget, F R; Kent, N; Kirsanov, M M; Klimov, O; Kokkonen, J; Kovzelev, A; Krasnoperov, A V; Kustov, D; Lacaprara, S; Lachaud, C; Lakic, B; Lanza, A; La Rotonda, L; Laveder, M; Letessier-Selvon, A A; Lévy, J M; Linssen, Lucie; Ljubicic, A; Long, J; Lupi, A; Marchionni, A; Martelli, F; Méchain, X; Mendiburu, J P; Meyer, J P; Mezzetto, Mauro; Mishra, S R; Moorhead, G F; Naumov, D V; Nédélec, P; Nefedov, Yu A; Nguyen-Mau, C; Orestano, D; Pastore, F; Peak, L S; Pennacchio, E; Pessard, H; Petti, R; Placci, A; Polesello, G; Pollmann, D; Polyarush, A Yu; Popov, B; Poulsen, C; Rebuffi, L; Renò, R; Rico, J; Riemann, P; Roda, C; Rubbia, André; Salvatore, F; Schahmaneche, K; Schmidt, B; Schmidt, T; Sconza, A; Sevior, M E; Sillou, D; Soler, F J P; Sozzi, G; Steele, D; Stiegler, U; Stipcevic, M; Stolarczyk, T; Tareb-Reyes, M; Taylor, G; Tereshchenko, V V; Toropin, A N; Touchard, A M; Tovey, Stuart N; Tran, M T; Tsesmelis, E; Ulrichs, J; Vacavant, L; Valdata-Nappi, M; Valuev, V Y; Vannucci, François; Varvell, K E; Veltri, M; Vercesi, V; Vidal-Sitjes, G; Vieira, J M; Vinogradova, T G; Weber, F V; Weisse, T; Wilson, F F; Winton, L J; Yabsley, B D; Zaccone, Henri; Zuber, K; Zuccon, P

    2001-01-01

    We present the results of a search for nu(mu)-->nu(e) oscillations in the NOMAD experiment at CERN. The experiment looked for the appearance of nu(e) in a predominantly nu(mu) wide-band neutrino beam at the CERN SPS. No evidence for oscillations was found. The 90% confidence limits obtained are delta m^2 10 eV^2.

  17. Search for $\

    Astier, Pierre; Baldisseri, Alberto; Baldo-Ceolin, Massimilla; Banner, M; Bassompierre, Gabriel; Benslama, K; Besson, N; Bird, I; Blumenfeld, B; Bobisut, F; Bouchez, J; Boyd, S; Bueno, A G; Bunyatov, S A; Camilleri, L L; Cardini, A; Cattaneo, Paolo Walter; Cavasinni, V; Cervera-Villanueva, A; Challis, R C; Chukanov, A; Collazuol, G; Conforto, G; Conta, C; Contalbrigo, M; Cousins, R D; Daniels, D; De Santo, A; Degaudenzi, H M; Del Prete, T; Di Lella, L; Dignan, T; Dumarchez, J; Feldman, G J; Ferrari, A; Ferrari, R; Ferrère, D; Flaminio, Vincenzo; Fraternali, M; Gaillard, J M; Gangler, E; Geiser, A; Geppert, D; Gibin, D; Gninenko, S N; Godley, A; Gosset, J; Gouanère, M; Grant, A; Graziani, G; Guglielmi, A M; Gómez-Cadenas, J J; Gössling, C; Hagner, C; Hernando, J; Hong, T M; Hubbard, D B; Hurst, P; Hyett, N; Iacopini, E; Joseph, C L; Juget, F R; Kent, N; Kirsanov, M M; Klimov, O; Kokkonen, J; Kovzelev, A; Krasnoperov, A V; Kustov, D; La Rotonda, L; Lacaprara, S; Lachaud, C; Lakic, B; Lanza, A; Laveder, M; Letessier-Selvon, A A; Linssen, Lucie; Ljubicic, A; Long, J; Lupi, A; Lévy, J M; Marchionni, A; Martelli, F; Mendiburu, J P; Meyer, J P; Mezzetto, Mauro; Mishra, S R; Moorhead, G F; Méchain, X; Naumov, D V; Nefedov, Yu A; Nguyen-Mau, C; Nédélec, P; Orestano, D; Pastore, F; Peak, L S; Pennacchio, E; Pessard, H; Petti, R; Placci, A; Polesello, G; Pollmann, D; Polyarush, A Yu; Popov, B; Poulsen, C; Rebuffi, L; Renò, R; Rico, J; Riemann, P; Roda, C; Rubbia, André; Salvatore, F; Schahmaneche, K; Schmidt, B; Schmidt, T; Sconza, A; Sevior, M E; Shih, D; Sillou, D; Soler, F J P; Sozzi, G; Steele, D; Stiegler, U; Stipcevic, M; Stolarczyk, T; Tareb-Reyes, M; Taylor, G N; Tereshchenko, V V; Toropin, A N; Touchard, A M; Tovey, Stuart N; Tran, M T; Tsesmelis, E; Ulrichs, J; Vacavant, L; Valdata-Nappi, M; Valuev, V Yu; Vannucci, François; Varvell, K E; Veltri, M; Vercesi, V; Vidal-Sitjes, G; Vieira, J M; Vinogradova, T G; Weber, F V; Weisse, T; Wilson, F F; Winton, L J; Yabsley, B D; Zaccone, Henri; Zuber, K; Zuccon, P; do Couto e Silva, E

    2003-01-01

    We present the results of a search for nu_mu → nu_e oscillations in the NOMAD experiment at Cern. The experiment looked for the appearance of nu_e in a predominantly nu_mu wide-band neutrino beam at the CERN SPS. No evidence for oscillations was found. The 90% confidence limits obtained are Delta m^2 ~ 10 eV^2.

  18. Accelerator-based BNCT

    The activity in accelerator development for accelerator-based BNCT (AB-BNCT) both worldwide and in Argentina is described. Projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators are briefly presented. In particular, the present status and recent progress of the Argentine project will be reviewed. The topics will cover: intense ion sources, accelerator tubes, transport of intense beams, beam diagnostics, the 9Be(d,n) reaction as a possible neutron source, Beam Shaping Assemblies (BSA), a treatment room, and treatment planning in realistic cases. - Highlights: • The activity in accelerator development for accelerator-based BNCT (AB-BNCT) both worldwide and in Argentina is described. • Projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators are briefly presented. • The present status and recent progress of the Argentine project will be reviewed. • Topics cover intense ion sources, accelerator tubes, transport of intense beams and beam diagnostics, among others

  19. COLLECTIVE-FIELD ACCELERATION

    Sessler, Andrew M.

    1969-07-04

    Diverse methods proposed for the acceleration of particles by means of collective fields are reviewed. A survey is made of the various currently active experimental programs devoted to investigating collective acceleration, and the present status of the research is briefly noted.

  20. Racetrack linear accelerators

    An improved recirculating electron beam linear accelerator of the racetrack type is described. The system comprises a beam path of four straight legs with four Pretzel bending magnets at the end of each leg to direct the beam into the next leg of the beam path. At least one of the beam path legs includes a linear accelerator. (UK)

  1. Hamburg Accelerator Conference (2)

    From 20-24 July, Hamburg welcomed the Fifteenth International Conference on High Energy Accelerators (HEACC). The HEACC Conference traditionally reviews the status of all major accelerator projects whether they are already running like clockwork, still in the construction phase, or waiting impatiently for financial approval

  2. Asia honours accelerator physicists

    2010-01-01

    "Steve Meyers of Cern and Jie Wei of Beijing's Tsinghua University are the first recipients of a new prize for particle physics. The pair were honoured for their contributions to numerous particle-accelerator projects - including Cern's Large Hadron Collider - by the Asian Committee for Future Accelerators (ACFA)..." (1 paragraph)

  3. Accelerators for energy production

    A tremendous progress of accelerators for these several decades, has been motivated mainly by the research on subnuclear physics. The culmination in high energy accelerators might be SSC, 20 TeV collider in USA, probably the ultimate accelerator being built with the conventional principle. The technology cultivated and integrated for the accelerator development, can now stably offer the high power beam which could be used for the energy problems. The Inertial Confinement Fusion (ICF) with high current, 10 kA and short pulse, 20 ns heavy ion beam (HIB) of mass number ∼200, would be the most promising application of accelerators for energy production. In this scenario, the fuel containing D-T mixture, will be compressed to the high temperature, ∼10 keV and to the high density state, ∼1000 times the solid density with the pressure of ablative plasma or thermal X ray produced by bombarding of high power HIB. The efficiency, beam power/electric power for accelerator, and the repetition rate of HIB accelerators could be most suitable for the energy production. In the present paper, the outline of HIB ICF (HIF) is presented emphasizing the key issues of high current heavy ion accelerator system. (author)

  4. KEK digital accelerator

    Iwashita, T.; Adachi, T.; Takayama, K.; Leo, K. W.; Arai, T.; Arakida, Y.; Hashimoto, M.; Kadokura, E.; Kawai, M.; Kawakubo, T.; Kubo, Tomio; Koyama, K.; Nakanishi, H.; Okazaki, K.; Okamura, K.; Someya, H.; Takagi, A.; Tokuchi, A.; Wake, M.

    2011-07-01

    The High Energy Accelerator Research Organization KEK digital accelerator (KEK-DA) is a renovation of the KEK 500 MeV booster proton synchrotron, which was shut down in 2006. The existing 40 MeV drift tube linac and rf cavities have been replaced by an electron cyclotron resonance (ECR) ion source embedded in a 200 kV high-voltage terminal and induction acceleration cells, respectively. A DA is, in principle, capable of accelerating any species of ion in all possible charge states. The KEK-DA is characterized by specific accelerator components such as a permanent magnet X-band ECR ion source, a low-energy transport line, an electrostatic injection kicker, an extraction septum magnet operated in air, combined-function main magnets, and an induction acceleration system. The induction acceleration method, integrating modern pulse power technology and state-of-art digital control, is crucial for the rapid-cycle KEK-DA. The key issues of beam dynamics associated with low-energy injection of heavy ions are beam loss caused by electron capture and stripping as results of the interaction with residual gas molecules and the closed orbit distortion resulting from relatively high remanent fields in the bending magnets. Attractive applications of this accelerator in materials and biological sciences are discussed.

  5. Accelerators Beyond The Tevatron?

    Lach, Joseph; /Fermilab

    2010-07-01

    Following the successful operation of the Fermilab superconducting accelerator three new higher energy accelerators were planned. They were the UNK in the Soviet Union, the LHC in Europe, and the SSC in the United States. All were expected to start producing physics about 1995. They did not. Why?

  6. Accelerator for nuclear transmutation

    A review on nuclear transmutation of radioactive wastes using particle accelerators is given. Technical feasibility, nuclear data, costs of various projects are discussed. It appears that one high energy accelerator (1500 MeV, 300 mA proton) could probably handle the amount of actinides generated by the actual French nuclear program

  7. Thoughts of accelerator tubes

    A brief, subjective review is given of mechanisms that may be limiting electrostatic accelerator tubes to present levels of performance. Suggestions are made for attacking these limitations with the purpose of stimulating the thinking of designers and users of electrostatic accelerators

  8. Mapping of VSG similarities in Trypanosoma brucei.

    Weirather, Jason L; Wilson, Mary E; Donelson, John E

    2012-02-01

    The protozoan parasite Trypanosoma brucei switches its variant surface glycoprotein (VSG) to subvert its mammalian hosts' immune responses. The T. brucei genome contains as many as 1600 VSG genes (VSGs), but most are silent noncoding pseudogenes. Only one functional VSG, located in a telomere-linked expression site, is transcribed at a time. Silent VSGs are copied into a VSG expression site through gene conversion. Truncated gene conversion events can generate new mosaic VSGs with segments of sequence identity to other VSGs. To examine the VSG family sub-structure within which these events occur, we combined the available VSG sequences and annotations with scripted BLAST searches to map the relationships among VSGs in the T. brucei genome. Clusters of related VSGs were visualized in 2- and 3-dimensions for different N- and C-terminal regions. Five types of N-termini (N1-N5) were observed, within which gene recombinational events are likely to occur, often with fully-coding 'functional' or 'atypical'VSGs centrally located between more dissimilar VSGs. Members of types N1, N3 and N4 are most closely related in the middle of the N-terminal region, whereas type N2 members are more similar near the N-terminus. Some preference occurs in pairing between specific N- and C-terminal types. Statistical analyses indicated no overall tendency for more related VSGs to be located closer in the genome than less related VSGs, although exceptions were noted. Many potential mosaic gene formation events within each N-terminal type were identified, contrasted by only one possible mosaic gene formation between N-terminal types (N1 and N2). These data suggest that mosaic gene formation is a major contributor to the overall VSG diversity, even though gene recombinational events between members of different N-terminal types occur only rarely. PMID:22079099

  9. Enhancing Solution Similarity in Multi-Objective Vehicle Routing Problems with Different Demand Periods

    Murata, Tadahiko; Itai, Ryota

    2008-01-01

    In this chapter, we proposed a local search that can be used in a two-fold EMO algorithm for multiple-objective VRPs with different demands. The simulation results show that the proposed method have the fine effectiveness to enhance the similarity of obtained routes for vehicles. Although the local search slightly deteriorates the maximum duration, it improves the similarity of the routes that may decrease the possibility of getting lost the way of drivers. If drivers get lost their ways duri...

  10. Maximal Acceleration Is Nonrotating

    Page, D N

    1998-01-01

    In a stationary axisymmetric spacetime, the angular velocity of a stationary observer that Fermi-Walker transports its acceleration vector is also the angular velocity that locally extremizes the magnitude of the acceleration of such an observer, and conversely if the spacetime is also symmetric under reversing both t and phi together. Thus a congruence of Nonrotating Acceleration Worldlines (NAW) is equivalent to a Stationary Congruence Accelerating Locally Extremely (SCALE). These congruences are defined completely locally, unlike the case of Zero Angular Momentum Observers (ZAMOs), which requires knowledge around a symmetry axis. The SCALE subcase of a Stationary Congruence Accelerating Maximally (SCAM) is made up of stationary worldlines that may be considered to be locally most nearly at rest in a stationary axisymmetric gravitational field. Formulas for the angular velocity and other properties of the SCALEs are given explicitly on a generalization of an equatorial plane, infinitesimally near a symmetry...

  11. Collinear wake field acceleration

    In the Voss-Weiland scheme of wake field acceleration a high current, ring-shaped driving bunch is used to accelerate a low current beam following along on axis. In such a structure, the transformer ratio, i.e., the ratio of maximum voltage that can be gained by the on-axis beam and the voltage lost by the driving beam, can be large. In contrast, it has been observed that for an arrangement in which driving and driven bunches follow the same path, and where the current distribution of both bunches is gaussian, the transformer ratio is not normally greater than two. This paper explores some of the possibilities and limitations of a collinear acceleration scheme. In addition to its application to wake field acceleration in structures, this study is also of interest for the understanding of the plasma wake field accelerator. 11 refs., 4 figs

  12. Controllable Laser Ion Acceleration

    Kawata, S.; Kamiyama, D.; Ohtake, Y.; Takano, M.; Barada, D.; Kong, Q.; Wang, P. X.; Gu, Y. J.; Wang, W. M.; Limpouch, J.; Andreev, A.; Bulanov, S. V.; Sheng, Z. M.; Klimo, O.; Psikal, J.; Ma, Y. Y.; Li, X. F.; Yu, Q. S.

    2016-02-01

    In this paper a future laser ion accelerator is discussed to make the laser-based ion accelerator compact and controllable. Especially a collimation device is focused in this paper. The future laser ion accelerator should have an ion source, ion collimators, ion beam bunchers, and ion post acceleration devices [Laser Therapy 22, 103(2013)]: the ion particle energy and the ion energy spectrum are controlled to meet requirements for a future compact laser ion accelerator for ion cancer therapy or for other purposes. The energy efficiency from the laser to ions is improved by using a solid target with a fine sub-wavelength structure or a near-critical density gas plasma. The ion beam collimation is performed by holes behind the solid target or a multi-layered solid target. The control of the ion energy spectrum and the ion particle energy, and the ion beam bunching would be successfully realized by a multistage laser-target interaction.

  13. Linear induction accelerator

    This paper examines a new layout for the injector and accelerating sectins of a linear induction accelerator. The sections are combined in a single housing: an induction system with a current-pulse generator based on double strip shaping lines laid over ferromagnetic cores; a multichannel spark discharger with forced current division among channels; and a system for core demagnetization and electron-beam formation and transport. The results of formation of an electron beam in the injector system and its acceleration in the first accelerating section of the accelerator for injection of beams with energies of 0.2-0.4 MeV, currents of 1-2 kA, and pulse durations of 60 nsec are given

  14. Accelerating DSMC data extraction.

    Gallis, Michail A.; Piekos, Edward Stanley

    2006-10-01

    In many direct simulation Monte Carlo (DSMC) simulations, the majority of computation time is consumed after the flowfield reaches a steady state. This situation occurs when the desired output quantities are small compared to the background fluctuations. For example, gas flows in many microelectromechanical systems (MEMS) have mean speeds more than two orders of magnitude smaller than the thermal speeds of the molecules themselves. The current solution to this problem is to collect sufficient samples to achieve the desired resolution. This can be an arduous process because the error is inversely proportional to the square root of the number of samples so we must, for example, quadruple the samples to cut the error in half. This work is intended to improve this situation by employing more advanced techniques, from fields other than solely statistics, for determining the output quantities. Our strategy centers on exploiting information neglected by current techniques, which collect moments in each cell without regard to one another, values in neighboring cells, nor their evolution in time. Unlike many previous acceleration techniques that modify the method itself, the techniques examined in this work strictly post-process so they may be applied to any DSMC code without affecting its fidelity or generality. Many potential methods are drawn from successful applications in a diverse range of areas, from ultrasound imaging to financial market analysis. The most promising methods exploit relationships between variables in space, which always exist in DSMC due to the absence of shocks. Disparate techniques were shown to produce similar error reductions, suggesting that the results shown in this report may be typical of what is possible using these methods. Sample count reduction factors of approximately three to five were found to be typical, although factors exceeding ten were shown on some variables under some techniques.

  15. CAS CERN accelerator school: 5. general accelerator physics course. Vol. 2. Proceedings

    The fifth CERN Accelerator School (CAS) basic course on General Accelerator Physics was given at the University of Jyvaeskylae, Finland, from 7 to 18 September 1992. Its syllabus was based on the previous similar courses held at Gif-sur-Yvette in 1984, Aarhus 1986, Salamanca 1988 and Juelich 1990, and whose proceedings were published as CERN Reports 85-19, 87-10, 89-05 and 91-04, respectively. However, certain topics were treated in a different way, improved or extended, while new subjects were introduced. As far as the proceedings of this school are concerned the opportunity was taken not only to include the lectures presented but also to select and revise the most appropriate chapters from the previous similar schools. In this way the present volumes constitute a rather complete introduction to all aspects of the design and construction of particle accelerators, including optics, emittance, luminosity, longitudinal and transverse beam dynamics, insertions, chromaticity, transfer lines, resonances, accelerating structures, tune shifts, coasting beams, lifetime, synchrotron radiation, radiation damping, beam-beam effects, diagnostics, cooling, ion and positron sources, RF and vacuum systems, injection and extraction, conventional, permanent and superconducting magnets, cyclotrons, RF linear accelerators, microtrons, as well as applications of particle accelerators (including therapy) and the history of accelerators. See hints under the relevant topics. (orig.)

  16. Future Accelerators Seminar in Japan

    ICFA, the International Committee for Future Accelerators, was set up by the Particles and Fields Commission of the International Union of Pure and Applied Physics (IUPAP) in 1976. Its mandate was 'To organize workshops for the study of problems related to an international super-high energy accelerator complex (VBA) and to elaborate the framework of its construction and of its use. To organize meetings for the exchange of information on future plans of regional facilities and for the formulation of advice on joint studies and uses.' In the seven years of its existence (it first met in August 1977), ICFA has organized three workshops on the first topic — t w o on 'Possibilities and Limitations of Accelerators and Detectors' (Fermilab, 1978 and Les Diablerets, 1979) and one on 'Possibilities and Limitations for Superconducting Accelerator Magnets' (Protvino, 1981). At an ICFA meeting at Fermilab in August 1983, it was realized that the second topic had been somewhat neglected. It was therefore decided to postpone a fourth workshop scheduled at the Japanese National Laboratory for High Energy Physics (KEK) and to organize instead a Seminar on 'Future Perspectives in High Energy Physics' similar to that held in New Orleans in 1975, which had in fact led to the creation of ICFA.The Seminar (jointly hosted by the Institute of Nuclear Study of Tokyo University and KEK, with support from the Ministry of Education, Science and Culture, the Yamada Science Foundation and the Nishina Memorial Foundation) took place from 14-20 May. There were about a hundred participants, mostly senior scientists from Western and Eastern Europe, USA, USSR and Japan (including the Directors of almost all the major high energy physics Laboratories) and representatives from Australia, Canada, China, India, Mexico, South Korea and Vietnam

  17. METRIC OF ACCELERATING AND ROTATING REFERENCE SYSTEMS IN GENERAL RELATIVITY

    Trunev A. P.

    2015-01-01

    Metric describing the accelerated and rotating reference system in general relativity in the case of an arbitrary dependence of acceleration and angular velocity on time has been proposed. It is established that the curvature tensor in such metrics is zero, which corresponds to movement in the flat spaces. It is shown that the motion of test bodies in the metric accelerated and rotating reference system in general relativity is similarly to the classical motion in non-inertial reference frame...

  18. Brasofensine NeuroSearch.

    Yu, P

    2000-12-01

    Brasofensine (NS-2214) is a dopamine reuptake inhibitor under development by NeuroSearch for the potential treatment of Parkinson's disease (PD) [178224]. The compound entered phase II trials in Denmark in November 1996, and phase I trials in the US in January 1996 [195505], [206604]. Bristol-Myers Squibb (BMS) had been codeveloping the compound until June 1999, when it decided to withdraw from the collaboration due to financial restraints of further regulatory requirements (such as additional toxicology documentation) [318365], [329665]. NeuroSearch was seeking licensing agreements with one or more international pharmaceutical companies to accelerate the development and marketing of brasofensine [187758] and had plans to meet with new potential partners for discussions concerning brasofensine licensing in late 1999 [337221]. A more complete evaluation of the effects of brasofensine was anticipated to be obtained through controlled trials, of at least 3 months duration, comparing it with a placebo and the marketed anti-Parkinson's drug, L-DOPA [317406]. In addition, further animal (monkey) tests were planned in order to document the safety of the drug in long-term treatment. These studies were expected to be discussed with the US FDA in October 1999 and, if satisfactory, the 3-month clinical trials were planned to commence in mid-2000 [337221]. At a meeting with the FDA during 1999, NeuroSearch presented plans for developing brasofensine alone. These were found to be satisfactory on condition that further preclinical studies were performed prior to any more clinical development [371542]. In August 2000, Lehman Brothers predicted worldwide sales of US $45 million in 2002 and US $175 million in 2003 [389229]. In February 1999, Lehman Brothers predicted the drug had a 35% probability of reaching market, with an estimated first launch date in 2002. The analysts predicted peak sales would occur in 2009, with sales of $250 million at that time [319225]. PMID:11249705

  19. Coherent and incoherent nonparaxial self-accelerating Weber beams

    Zhang, Yiqi; Wen, Feng; Li, Changbiao; Zhang, Zhaoyang; Zhang, Yanpeng; Belić, Milivoj R

    2016-01-01

    We investigate the coherent and incoherent nonparaxial Weber beams, theoretically and numerically. We show that the superposition of coherent self-accelerating Weber beams with transverse displacement cannot display the nonparaxial accelerating Talbot effect. The reason is that their lobes do not accelerate in unison, which is a requirement for the appearance of the effect. While for the incoherent Weber beams, they naturally cannot display the accelerating Talbot effect but can display the nonparaxial accelerating properties, although the transverse coherence length is smaller than the beam width, based on the second-order coherence theory. Our research method directly applies to the nonparaxial Mathieu beams as well, and one will obtain similar conclusions as for the Weber beams, although this is not discussed in the paper. Our investigation identifies families of nonparaxial accelerating beams that do not exhibit the accelerating Talbot effect, and in addition broadens the understanding of coherence proper...

  20. An experimental investigation on self-acceleration of cellular spherical flames

    Wu, Fujia; Jomaas, Grunde; Law, Chung K.

    2013-01-01

    The cells that continuously develop over the flame surface of an expanding spherical flame increase its area and thereby the global propagation rate, resulting in the possibility of self-acceleration. The present study examines whether this self-acceleration could be self-similar, and, if so...... demonstrate the strong possibility of self-similar flame acceleration, weak influence of the system pressure and diffusional-thermal instability, and a corresponding moderate spread in the power-law acceleration exponent....

  1. Multimode Process Fault Detection Using Local Neighborhood Similarity Analysis☆

    Xiaogang Deng; Xuemin Tian

    2014-01-01

    Traditional data driven fault detection methods assume unimodal distribution of process data so that they often perform not wel in chemical process with multiple operating modes. In order to monitor the multimode chemical process effectively, this paper presents a novel fault detection method based on local neighborhood similarity analysis (LNSA). In the proposed method, prior process knowledge is not required and only the multimode normal operation data are used to construct a reference dataset. For online monitoring of process state, LNSA applies moving window technique to obtain a current snapshot data window. Then neighborhood searching technique is used to acquire the corresponding local neighborhood data window from the reference dataset. Similarity analysis between snapshot and neighborhood data windows is performed, which includes the calculation of principal component analysis (PCA) similarity factor and distance similarity factor. The PCA similarity factor is to capture the change of data direction while the distance similarity factor is used for monitoring the shift of data center position. Based on these similarity factors, two monitoring statistics are built for multimode process fault detection. Final y a simulated continuous stirred tank system is used to demonstrate the effectiveness of the proposed method. The simulation results show that LNSA can detect multimode process changes effectively and performs better than traditional fault detection methods.

  2. Dependency Similarity, Attraction and Perceived Happiness.

    Pandey, Janak

    1978-01-01

    Subjects were asked to evaluate either a similar personality or a dissimilar personality. Subjects rated similar others more positively than dissimilar others and, additionally, perceived similar others as more helpful and sympathetic than dissimilar others. (Author)

  3. The Search for Directed Intelligence

    Lubin, Philip

    2016-01-01

    We propose a search for sources of directed energy systems such as those now becoming technologically feasible on Earth. Recent advances in our own abilities allow us to foresee our own capability that will radically change our ability to broadcast our presence. We show that systems of this type have the ability to be detected at vast distances and indeed can be detected across the entire horizon. This profoundly changes the possibilities for searches for extra-terrestrial technology advanced civilizations. We show that even modest searches can be extremely effective at detecting or limiting many civilization classes. We propose a search strategy that will observe more than 10 12 stellar and planetary systems with possible extensions to more than 10 20 systems allowing us to test the hypothesis that other similarly or more advanced civilization with this same capability, and are broadcasting, exist.

  4. Accelerator programme at CAT

    The Accelerator Programme at the Centre for Advanced Technology (CAT), Indore, has very broad based concept under which all types of accelerators are to be taken up for design and fabrication. This centre will be housing a wide variety of accelerators to serve as a common facility for the universities, national laboratories in addition to laboratories under the Department of Atomic Energy. In the first phase of the programme, a series of electron accelerators are designed and fabricated. They are synchrotron radiation sources of 450 MeV (INDUS-I) and of 2 GeV (INDUS-II), microtron upto energy of 20 MeV, linear accelerator upto 20 MeV, and DC Accelerator for industrial irradiation upto 750 KeV and 20 KW. A proton accelerator of 300 MeV with 20 MeV linac injector is also designed. CAT is also developing a strong base for support technologies like ultra high vacuum, radio frequency and microwaves, DC pulsed and superconducting magnets, power supplies and controls etc. These technologies are very useful for other industrial applications also. To develop user groups to utilise INDUS-II synchrotron radiation source, a batch production of rotating Anode X-ray generators with power supplies has been initiated. So also, the sputter ion pumps, electron guns, turbo molecular pumps are brought into batch production. (author)

  5. The miniature accelerator

    Antonella Del Rosso

    2015-01-01

    The image that most people have of CERN is of its enormous accelerators and their capacity to accelerate particles to extremely high energies. But thanks to some cutting-edge studies on beam dynamics and radiofrequency technology, along with innovative construction techniques, teams at CERN have now created the first module of a brand-new accelerator, which will be just 2 metres long. The potential uses of this miniature accelerator will include deployment in hospitals for the production of medical isotopes and the treatment of cancer. It’s a real David-and-Goliath story.   Serge Mathot, in charge of the construction of the "mini-RFQ", pictured with the first of the four modules that will make up the miniature accelerator. The miniature accelerator consists of a radiofrequency quadrupole (RFQ), a component found at the start of all proton accelerator chains around the world, from the smallest to the largest. The LHC is designed to produce very high-intensity beams ...

  6. Collective ion acceleration

    Progress achieved in the understanding and development of collective ion acceleration is presented. Extensive analytic and computational studies of slow cyclotron wave growth on an electron beam in a helix amplifier were performed. Research included precise determination of linear coupling between beam and helix, suppression of undesired transients and end effects, and two-dimensional simulations of wave growth in physically realizable systems. Electrostatic well depths produced exceed requirements for the Autoresonant Ion Acceleration feasibility experiment. Acceleration of test ions to modest energies in the troughs of such waves was also demonstrated. Smaller efforts were devoted to alternative acceleration mechanisms. Langmuir wave phase velocity in Converging Guide Acceleration was calculated as a function of the ratio of electron beam current to space-charge limiting current. A new collective acceleration approach, in which cyclotron wave phase velocity is varied by modulation of electron beam voltage, is proposed. Acceleration by traveling Virtual Cathode or Localized Pinch was considered, but appears less promising. In support of this research, fundamental investigations of beam propagation in evacuated waveguides, of nonneutral beam linear eigenmodes, and of beam stability were carried out. Several computer programs were developed or enhanced. Plans for future work are discussed

  7. Collective ion acceleration

    Godfrey, B.B.; Faehl, R.J.; Newberger, B.S.; Shanahan, W.R.; Thode, L.E.

    1977-01-01

    Progress achieved in the understanding and development of collective ion acceleration is presented. Extensive analytic and computational studies of slow cyclotron wave growth on an electron beam in a helix amplifier were performed. Research included precise determination of linear coupling between beam and helix, suppression of undesired transients and end effects, and two-dimensional simulations of wave growth in physically realizable systems. Electrostatic well depths produced exceed requirements for the Autoresonant Ion Acceleration feasibility experiment. Acceleration of test ions to modest energies in the troughs of such waves was also demonstrated. Smaller efforts were devoted to alternative acceleration mechanisms. Langmuir wave phase velocity in Converging Guide Acceleration was calculated as a function of the ratio of electron beam current to space-charge limiting current. A new collective acceleration approach, in which cyclotron wave phase velocity is varied by modulation of electron beam voltage, is proposed. Acceleration by traveling Virtual Cathode or Localized Pinch was considered, but appears less promising. In support of this research, fundamental investigations of beam propagation in evacuated waveguides, of nonneutral beam linear eigenmodes, and of beam stability were carried out. Several computer programs were developed or enhanced. Plans for future work are discussed.

  8. Large electrostatic accelerators

    Jones, C.M.

    1984-01-01

    The increasing importance of energetic heavy ion beams in the study of atomic physics, nuclear physics, and materials science has partially or wholly motivated the construction of a new generation of large electrostatic accelerators designed to operate at terminal potentials of 20 MV or above. In this paper, the author briefly discusses the status of these new accelerators and also discusses several recent technological advances which may be expected to further improve their performance. The paper is divided into four parts: (1) a discussion of the motivation for the construction of large electrostatic accelerators, (2) a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, (3) a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and (4) a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year. Due to time and space constraints, discussion is restricted to consideration of only tandem accelerators.

  9. Searching for uranium

    In the not-so-distant past, the search for uranium usually followed a conceptual approach in which an unexplored terrain was selected because of its presumed similarities with one that is known to contain one or more deposits. A description, in general terms, is given of the methodology adopted during the different stages of the exploration programme, up to the point of a discovery. Three case histories prove that, in order to reach this point, a certain amount of improvisation and luck is usually required. (author)

  10. Autonomous Search

    Hamadi, Youssef; Saubion, Frédéric

    2012-01-01

    Decades of innovations in combinatorial problem solving have produced better and more complex algorithms. These new methods are better since they can solve larger problems and address new application domains. They are also more complex which means that they are hard to reproduce and often harder to fine-tune to the peculiarities of a given problem. This last point has created a paradox where efficient tools are out of reach of practitioners. Autonomous search (AS) represents a new research field defined to precisely address the above challenge. Its major strength and originality consist in the

  11. RF linear accelerators

    Wangler, Thomas P

    2008-01-01

    Thomas P. Wangler received his B.S. degree in physics from Michigan State University, and his Ph.D. degree in physics and astronomy from the University of Wisconsin. After postdoctoral appointments at the University of Wisconsin and Brookhaven National Laboratory, he joined the staff of Argonne National Laboratory in 1966, working in the fields of experimental high-energy physics and accelerator physics. He joined the Accelerator Technology Division at Los Alamos National Laboratory in 1979, where he specialized in high-current beam physics and linear accelerator design and technology. In 2007

  12. Entropic accelerating universe

    Easson, Damien A., E-mail: easson@asu.ed [Institute for the Physics and Mathematics of the Universe, University of Tokyo, Kashiwa, Chiba 277-8568 (Japan); Department of Physics and School of Earth and Space Exploration and Beyond Center, Arizona State University, Phoenix, AZ 85287-1504 (United States); Kavli Institute for Theoretical Physics, University of California, Santa Barbara, CA 93106-4030 (United States); Frampton, Paul H., E-mail: frampton@physics.unc.ed [Institute for the Physics and Mathematics of the Universe, University of Tokyo, Kashiwa, Chiba 277-8568 (Japan); Department of Physics and Astronomy, University of North Carolina, Chapel Hill, NC 27599 (United States); Smoot, George F., E-mail: gfsmoot@lbl.go [Institute for the Physics and Mathematics of the Universe, University of Tokyo, Kashiwa, Chiba 277-8568 (Japan); Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA 94720 (United States); Physics Department, University of California, Berkeley, CA 94720 (United States); Institute for the Early Universe, Ewha Womans University and Advanced Academy, Seoul (Korea, Republic of); Chaire Blaise Pascale, Universite Paris Denis Diderot, Paris (France)

    2011-01-31

    To accommodate the observed accelerated expansion of the universe, one popular idea is to invoke a driving term in the Friedmann-Lemaitre equation of dark energy which must then comprise 70% of the present cosmological energy density. We propose an alternative interpretation which takes into account the entropy and temperature intrinsic to the horizon of the universe due to the information holographically stored there. Dark energy is thereby obviated and the acceleration is due to an entropic force naturally arising from the information storage on the horizon surface screen. We consider an additional quantitative approach inspired by surface terms in general relativity and show that this leads to the entropic accelerating universe.

  13. Entropic accelerating universe

    To accommodate the observed accelerated expansion of the universe, one popular idea is to invoke a driving term in the Friedmann-Lemaitre equation of dark energy which must then comprise 70% of the present cosmological energy density. We propose an alternative interpretation which takes into account the entropy and temperature intrinsic to the horizon of the universe due to the information holographically stored there. Dark energy is thereby obviated and the acceleration is due to an entropic force naturally arising from the information storage on the horizon surface screen. We consider an additional quantitative approach inspired by surface terms in general relativity and show that this leads to the entropic accelerating universe.

  14. ACCELERATORS: School prizes

    Dedicated to its goal of encouraging scientists and students to work in the field of particle accelerators, the US Particle Accelerator School (operating since 1981) has switched to a new format. Starting this year, it will offer in alternate years basic accelerator physics plus advanced subjects in both university and symposium styles over four weeks. Expanding the school from two to four weeks gives additional flexibility, and undergraduate participation should be encouraged by university credits being offered for particular courses. In the intervening years, the school will organize six-day topical courses

  15. FMIT accelerator vacuum system

    The Fusion Materials Irradiation Test (FMIT) Facility accelerator is being designed to continuously accelerate 100-mA deuterons to 25 MeV. High vacuum pumping of the accelerator structure and beam lines will be done by ion pumps and titanium sublimation pumps. The design of the roughing system includes a Roots blower/mechanical pump package. For economy the size of the system has been designed to operate at 10-6 torr, where beam particle scattering on residual gases is negligible. For minimum maintenance in this neutron factory, the FMIT vacuum system is designed from the point of view of simplicity and reliability

  16. Hadron accelerators in medicine

    The application of hadron accelerators (protons and light ions) in cancer therapy is discussed. After a brief introduction on the rationale for the use of heavy charged particles in radiation therapy, a discussion is given on accelerator technology and beam delivery systems. Next, existing and planned facilities are briefly reviewed. The Italian Hadron-therapy Project is then described in some detail, with reference ro both the National Centre for Oncological Hadron-therapy and the design of different types of compact proton accelerators aimed at introducing proton therapy in a large umber of hospitals. (author)

  17. The auroral electron accelerator

    A model of the auroral electron acceleration process is presented in which the electrons are accelerated resonantly by lower-hybrid waves. The essentially stochastic acceleration process is approximated for the purposes of computation by a deterministic model involving an empirically derived energy transfer function. The empirical function, which is consistent with all that is known of electron energization by lower-hybrid waves, allows many, possibly all, observed features of the electron distribution to be reproduced. It is suggested that the process occurs widely in both space and laboratory plasmas. (author)

  18. Confronting Twin Paradox Acceleration

    Murphy, Thomas W.

    2016-05-01

    The resolution to the classic twin paradox in special relativity rests on the asymmetry of acceleration. Yet most students are not exposed to a satisfactory analysis of what exactly happens during the acceleration phase that results in the nonaccelerated observer's more rapid aging. The simple treatment presented here offers both graphical and quantitative solutions to the problem, leading to the correct result that the acceleration-induced age gap is 2Lβ years when the one-way distance L is expressed in light-years and velocity β ≡v/c .

  19. Auroral electron acceleration

    Two theories of auroral electron acceleration are discussed. Part 1 examines the currently widely held view that the acceleration is an ordered process in a quasi-static electric field. It is suggested that, although there are many factors seeming to support this theory, the major qualifications and uncertainties that have been identified combine to cast serious doubt over its validity. Part 2 is devoted to a relatively new interpretation in terms of stochastic acceleration in turbulent electric fields. This second theory, which appears to account readily for most known features of the electron distribution function, is considered to provide a more promising approach to this central question in magnetospheric plasma physics. (author)

  20. The particle accelerator

    As the Palais de la Decouverte (in Paris) is the sole scientific vulgarization establishment in the world to operate an actual particle accelerator able to provoke different types of nuclear reactions, the author recalls some historical aspects of the concerned department since the creation of the 'Radioactivity - Atom synthesis' department in 1937. He recalls the experiments which were then performed, the installation of the particle accelerator in 1964 and its renewal. He describes what's going on in this accelerator. He gives an overview of the difficulties faced after it has been decided to move it, of the works which had to be performed, and of radiation protection measures

  1. Accelerator Toolbox for MATLAB

    This paper introduces Accelerator Toolbox (AT)--a collection of tools to model particle accelerators and beam transport lines in the MATLAB environment. At SSRL, it has become the modeling code of choice for the ongoing design and future operation of the SPEAR 3 synchrotron light source. AT was designed to take advantage of power and simplicity of MATLAB--commercially developed environment for technical computing and visualization. Many examples in this paper illustrate the advantages of the AT approach and contrast it with existing accelerator code frameworks

  2. Web Search Engines: Search Syntax and Features.

    Ojala, Marydee

    2002-01-01

    Presents a chart that explains the search syntax, features, and commands used by the 12 most widely used general Web search engines. Discusses Web standardization, expanded types of content searched, size of databases, and search engines that include both simple and advanced versions. (LRW)

  3. Database search van tijdreeksen, met toepassing in de firma Medtronic

    KELLENS, Tom

    2006-01-01

    In deze thesis richten we ons op het probleem van similarity search van tijdreeksen. Similarity search kan onderverdeeld worden in twee categorieën, nl. whole matching en subsequence matching. Dit laatste kan beschouwd worden als een veralgemening van whole matching. We zullen in dit werk zien hoe deze veralgemening met behulp van sliding window technieken kan gerealiseerd worden. Similarity search is in essentie gebaseerd op een afstandsfunctie. Op basis van het soort af...

  4. The Hofmethode: Computing Semantic Similarities between E-Learning Products

    Oliver Michel

    2009-11-01

    Full Text Available The key task in building useful e-learning repositories is to develop a system with an algorithm allowing users to retrieve information that corresponds to their specific requirements. To achieve this, products (or their verbal descriptions, i.e. presented in metadata need to be compared and structured according to the results of this comparison. Such structuring is crucial insofar as there are many search results that correspond to the entered keyword. The Hofmethode is an algorithm (based on psychological considerations to compute semantic similarities between texts and therefore offer a way to compare e-learning products. The computed similarity values are used to build semantic maps in which the products are visually arranged according to their similarities. The paper describes how the Hofmethode is implemented in the online database edulap, and how it contributes to help the user to explore the data in which he is interested.

  5. Enhancing Divergent Search through Extinction Events

    Lehman, Joel; Miikkulainen, Risto

    2015-01-01

    capacity to evolve. This hypothesis is tested through experiments in two evolutionary robotics domains. The results show that combining extinction events with divergent search increases evolvability, while combining them with convergent search offers no similar benefit. The conclusion is that extinction...

  6. Missing Links in Middle School: Developing Use of Disciplinary Relatedness in Evaluating Internet Search Results

    Keil, Frank C.; Kominsky, Jonathan F.

    2013-01-01

    In the “digital native” generation, internet search engines are a commonly used source of information. However, adolescents may fail to recognize relevant search results when they are related in discipline to the search topic but lack other cues. Middle school students, high school students, and adults rated simulated search results for relevance to the search topic. The search results were designed to contrast deep discipline-based relationships with lexical similarity to the search topic. R...

  7. Search for supernova debris on the Moon

    The enhanced deposition of 60Fe in a deep ocean ferro-manganese crust about (2.1±0.4) Myr ago indicate that one or more supernova (SN) explosions occurred in the vicinity of the Solar System. That observation was only possible with the ultrasensitive Accelerator Mass Spectrometry (AMS) technique at the Maier-Leibnitz-Laboratory, which is able to measure concentrations of 60Fe/Fe down to a level of 10-16 and even below. Due to its lack of atmosphere and its negligible sedimentation rate, the Lunar surface is an excellent quantitative reservoir for SN debris. We searched for live 60Fe (T1/2 = 2.62 x 106 yr) and 53Mn (T1/2 = 3.7 x 106 yr) in different samples from 3 Apollo missions. 53Mn is, similar as 26Al and 60Fe, a tool to trace nucleosynthesis activities. It is formed primarily during the explosive silicon-burning of the inner shells of SNe via 53Fe which β-decays to 53Mn. Samples where we found an enhanced 60Fe concentration showed also an enhancement of 53Mn. This could be the first detection of live 53Mn originating from recent nucleosynthesis.

  8. Search for supernova debris on the Moon

    Fimiani, Leticia; Faestermann, Thomas; Gomez Guzman, Jose Manuel; Hain, Karin; Korschinek, Gunther; Ludwig, Peter [Physics Department, Technische Universitaet Muenchen, Garching (Germany); Herzog, Gregory; Ligon, Bret; Park, Jisun [Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ (United States); Rugel, Georg [Forschungszentrum Dresden Rossendorf, Dresden (Germany)

    2014-07-01

    The enhanced deposition of {sup 60}Fe in a deep ocean ferro-manganese crust about (2.1±0.4) Myr ago indicate that one or more supernova (SN) explosions occurred in the vicinity of the Solar System. That observation was only possible with the ultrasensitive Accelerator Mass Spectrometry (AMS) technique at the Maier-Leibnitz-Laboratory, which is able to measure concentrations of {sup 60}Fe/Fe down to a level of 10{sup -16} and even below. Due to its lack of atmosphere and its negligible sedimentation rate, the Lunar surface is an excellent quantitative reservoir for SN debris. We searched for live {sup 60}Fe (T{sub 1/2} = 2.62 x 10{sup 6} yr) and {sup 53}Mn (T{sub 1/2} = 3.7 x 10{sup 6} yr) in different samples from 3 Apollo missions. {sup 53}Mn is, similar as {sup 26}Al and {sup 60}Fe, a tool to trace nucleosynthesis activities. It is formed primarily during the explosive silicon-burning of the inner shells of SNe via {sup 53}Fe which β-decays to {sup 53}Mn. Samples where we found an enhanced {sup 60}Fe concentration showed also an enhancement of {sup 53}Mn. This could be the first detection of live {sup 53}Mn originating from recent nucleosynthesis.

  9. Domain enhanced lookup time accelerated BLAST

    Boratyn Grzegorz M

    2012-04-01

    Full Text Available Abstract Background BLAST is a commonly-used software package for comparing a query sequence to a database of known sequences; in this study, we focus on protein sequences. Position-specific-iterated BLAST (PSI-BLAST iteratively searches a protein sequence database, using the matches in round i to construct a position-specific score matrix (PSSM for searching the database in round i + 1. Biegert and Söding developed Context-sensitive BLAST (CS-BLAST, which combines information from searching the sequence database with information derived from a library of short protein profiles to achieve better homology detection than PSI-BLAST, which builds its PSSMs from scratch. Results We describe a new method, called domain enhanced lookup time accelerated BLAST (DELTA-BLAST, which searches a database of pre-constructed PSSMs before searching a protein-sequence database, to yield better homology detection. For its PSSMs, DELTA-BLAST employs a subset of NCBI’s Conserved Domain Database (CDD. On a test set derived from ASTRAL, with one round of searching, DELTA-BLAST achieves a ROC5000 of 0.270 vs. 0.116 for CS-BLAST. The performance advantage diminishes in iterated searches, but DELTA-BLAST continues to achieve better ROC scores than CS-BLAST. Conclusions DELTA-BLAST is a useful program for the detection of remote protein homologs. It is available under the “Protein BLAST” link at http://blast.ncbi.nlm.nih.gov. Reviewers This article was reviewed by Arcady Mushegian, Nick V. Grishin, and Frank Eisenhaber.

  10. SPS accelerating cavity

    1983-01-01

    See photo 8202397: View towards the downstream end of one of the SPS accelerating cavities (200 MHz, travelling wave structure). See 7603195 and 8011289 for more details, 7411032 for the travelling wave structure, and also 8104138.

  11. SPS accelerating cavity

    1983-01-01

    View towards the downstream end of one of the SPS accelerating cavities (200 MHz, travelling wave structure). See 7603195 and 8011289 for more details, 7411032 for the travelling wave structure, and also 8104138.

  12. Applicatons of accelerators

    The great diversity of possible applications of accelerators has been demonstrated in the past few years. Apart from the more familiar uses of accelerators for fundamental particle, nuclear, and solid state physics research, the applications range from microscopic trace analysis through cancer therapy to nuclear power and large volume radiation processing. Accelerators are also being used for applied research in proton radiography, radiation damage studies, laser excitation and materials analysis. The required beam properties vary from an extremely low emittance with very low beam current to megawatt beam power with a low level of beam spill. At the Chalk River Nuclear Laboratories developments are underway on applications of accelerators to nuclear fuel breeding and to cancer therapy. (author)

  13. Non-accelerator experiments

    This report discusses several topics which can be investigated without the use of accelerators. Topics covered are: (1) proton decay, (2) atmospheric neutrinos, (3) neutrino detection, (4) muons from Cygnus X-3, and (5) the double-beta decay

  14. Joint International Accelerator School

    CERN Accelerator School

    2014-01-01

    The CERN and US Particle Accelerator Schools recently organised a Joint International Accelerator School on Beam Loss and Accelerator Protection, held at the Hyatt Regency Hotel, Newport Beach, California, USA from 5-14 November 2014. This Joint School was the 13th in a series of such schools, which started in 1985 and also involves the accelerator communities in Japan and Russia.   Photo courtesy of Alfonse Pham, Michigan State University.   The school attracted 58 participants representing 22 different nationalities, with around half from Europe and the other half from Asia and the Americas. The programme comprised 26 lectures, each of 90 minutes, and 13 hours of case study. The students were given homework each day and had an opportunity to sit a final exam, which counted towards university credit. Feedback from the participants was extremely positive, praising the expertise and enthusiasm of the lecturers, as well as the high standard and quality of their lectures. Initial dis...

  15. Rejuvenating CERN's Accelerators

    2004-01-01

    In the coming years and especially in 2005, CERN's accelerators are going to receive an extensive renovation programme to ensure they will perform reliably and effectively when the LHC comes into service.

  16. Vibration control in accelerators

    Montag, C.

    2011-01-01

    In the vast majority of accelerator applications, ground vibration amplitudes are well below tolerable magnet jitter amplitudes. In these cases, it is necessary and sufficient to design a rigid magnet support structure that does not amplify ground vibration. Since accelerator beam lines are typically installed at an elevation of 1-2m above ground level, special care has to be taken in order to avoid designing a support structure that acts like an inverted pendulum with a low resonance frequency, resulting in untolerable lateral vibration amplitudes of the accelerator components when excited by either ambient ground motion or vibration sources within the accelerator itself, such as cooling water pumps or helium flow in superconducting magnets. In cases where ground motion amplitudes already exceed the required jiter tolerances, for instance in future linear colliders, passive vibration damping or active stabilization may be considered.

  17. Acceleration of Logarithmic Convergence

    Gaskin, J. G.; Ford, W. F.

    1998-01-01

    In this paper, we shall give a characterization of all monotonically decreasing sequence of positive terms, whose sum converge and then introduce a Transformation which can be used to accelerate the convergence of a large class of logarithmically convergent series.

  18. Amps particle accelerator definition study

    Sellen, J. M., Jr.

    1975-01-01

    The Particle Accelerator System of the AMPS (Atmospheric, Magnetospheric, and Plasmas in Space) payload is a series of charged particle accelerators to be flown with the Space Transportation System Shuttle on Spacelab missions. In the configuration presented, the total particle accelerator system consists of an energetic electron beam, an energetic ion accelerator, and both low voltage and high voltage plasma acceleration devices. The Orbiter is illustrated with such a particle accelerator system.

  19. A symmetrical rail accelerator

    Igenbergs, E. (Technische Univ. Muenchen, Lehrstuhl fuer Raumfahrttechnik, Richard-Wagner-Strasse 18, 8000 Muenchen 2 (DE))

    1991-01-01

    This paper reports on the symmetrical rail accelerator that has four rails, which are arranged symmetrically around the bore. The opposite rails have the same polarity and the adjacent rails the opposite polarity. In this configuration the radial force acting upon the individual rails is significantly smaller than in a conventional 2-rail configuration and a plasma armature is focussed towards the axis of the barrel. Experimental results indicate a higher efficiency compared to a conventional rail accelerator.

  20. Entropic Accelerating Universe

    Easson, Damien A.; Frampton, Paul H.; Smoot, George F.

    2010-01-01

    To accommodate the observed accelerated expansion of the universe, one popular idea is to invoke a driving term in the Friedmann-Lemaitre equation of dark energy which must then comprise 70% of the present cosmological energy density. We propose an alternative interpretation which takes into account the entropy and temperature intrinsic to the horizon of the universe due to the information holographically stored there. Dark energy is thereby obviated and the acceleration is due to an entropic...

  1. Accelerated cyclic corrosion tests

    Prošek T.

    2016-01-01

    Accelerated corrosion testing is indispensable for material selection, quality control and both initial and residual life time prediction for bare and painted metallic, polymeric, adhesive and other materials in atmospheric exposure conditions. The best known Neutral Salt Spray (NSS) test provides unrealistic conditions and poor correlation to exposures in atmosphere. Modern cyclic accelerated corrosion tests include intermittent salt spray, wet and dry phases and eventually other technical p...

  2. CEBAF Accelerator Achievements

    In the past decade, nuclear physics users of Jefferson Lab's Continuous Electron Beam Accelerator Facility (CEBAF) have benefited from accelerator physics advances and machine improvements. As of early 2011, CEBAF operates routinely at 6 GeV, with a 12 GeV upgrade underway. This article reports highlights of CEBAF's scientific and technological evolution in the areas of cryomodule refurbishment, RF control, polarized source development, beam transport for parity experiments, magnets and hysteresis handling, beam breakup, and helium refrigerator operational optimization.

  3. Advanced Accelerator Concepts

    This conference proceedings represent the results of theThird Advanced Accelerator Concepts Workshop held in PortJefferson, New York. The workshop was sponsored by the U.S.Department of Energy, the Office of Navel Research and BrookhavenNational Laboratory. The purpose was to assess new techniques forproduction of ultra-high gradient acceleration and to addressengineering issues in achieving this goal. There are eighty-onepapers collected in the proceedings and all have been abstractedfor the database

  4. Self-similarity and transport in the standard map

    Anomalous transport is investigated for the Standard Map. A chain of exact self similar islands in the vicinity of the period 5 accelerator island is found for a particular value of the map parameter. The transport is found to be superdiffusive with an anomalous exponent related to the characteristic temporal and spatial scaling parameters of the island chain. The value of the transport exponent is compared to the theory. The escape time distribution and Poincare recurrence distribution are found to have power-like tails and the corresponding exponents are obtained and compared to the theory

  5. Nuclear physics accelerator facilities

    Brief descriptions are given of DOE and Nuclear Physics program operated and sponsored accelerator facilities. Specific facilities covered are the Argonne Tandem/Linac Accelerator System, the Tandem/AGS Heavy Ion Facility at Brookhaven National Laboratory, the proposed Continuous Beam Accelerator at Newport News, Virginia, the Triangle Universities Nuclear Laboratory at Duke University, the Bevalac and the SuperHILAC at Lawrence Berkeley Laboratory, the 88-Inch Cyclotron at Lawrence Berkeley Laboratory, the Clinton P. Anderson Meson Physics Facility at Los Alamos National Laboratory, the Bates Linear Accelerator Center at Massachusetts Institute of Technology, the Holifield Heavy Ion Research Facility at Oak Ridge National Laboratory, the Nuclear Physics Injector at Stanford Linear Accelerator Center, the Texas A and M Cyclotrons, the Tandem/Superconducting Booster Accelerator at the University of Washington and the Tandem Van de Graaff at the A.W. Wright Nuclear Structure Laboratory of Yale University. Included are acquisition cost, research programs, program accomplishments, future directions, and operating parameters of each facility

  6. Multimegawatt cyclotron autoresonance accelerator

    Means are discussed for generation of high-quality multimegawatt gyrating electron beams using rf gyroresonant acceleration. TE111-mode cylindrical cavities in a uniform axial magnetic field have been employed for beam acceleration since 1968; such beams have more recently been employed for generation of radiation at harmonics of the gyration frequency. Use of a TE11-mode waveguide for acceleration, rather than a cavity, is discussed. It is shown that the applied magnetic field and group velocity axial tapers allow resonance to be maintained along a waveguide, but that this is impractical in a cavity. In consequence, a waveguide cyclotron autoresonance accelerator (CARA) can operate with near-100% efficiency in power transfer from rf source to beam, while cavity accelerators will, in practice, have efficiency values limited to about 40%. CARA experiments are described in which an injected beam of up to 25 A, 95 kV has had up to 7.2 MW of rf power added, with efficiencies of up to 96%. Such levels of efficiency are higher than observed previously in any fast-wave interaction, and are competitive with efficiency values in industrial linear accelerators. Scaling arguments suggest that good quality gyrating megavolt beams with peak and average powers of 100 MW and 100 kW can be produced using an advanced CARA, with applications in the generation of high-power microwaves and for possible remediation of flue gas pollutants. copyright 1996 American Institute of Physics

  7. Accelerators for America's Future

    Bai, Mei

    2016-03-01

    Particle accelerator, a powerful tool to energize beams of charged particles to a desired speed and energy, has been the working horse for investigating the fundamental structure of matter and fundermental laws of nature. Most known examples are the 2-mile long Stanford Linear Accelerator at SLAC, the high energy proton and anti-proton collider Tevatron at FermiLab, and Large Hadron Collider that is currently under operation at CERN. During the less than a century development of accelerator science and technology that led to a dazzling list of discoveries, particle accelerators have also found various applications beyond particle and nuclear physics research, and become an indispensible part of the economy. Today, one can find a particle accelerator at almost every corner of our lives, ranging from the x-ray machine at the airport security to radiation diagnostic and therapy in hospitals. This presentation will give a brief introduction of the applications of this powerful tool in fundermental research as well as in industry. Challenges in accelerator science and technology will also be briefly presented

  8. APT accelerator technology

    The proposed accelerator production of tritium (APT) project requires an accelerator that provides a cw proton beam of 100 m A at 1300 MeV. Since the majority of the technical risk of a high-current cw (continuous-wave, 100% DF) accelerator resides in the low-energy section, Los Alamos is building a 20 MeV duplicate of the accelerator front end to confirm design codes, beam performance, and demonstrate operational reliability. We report on design details of this low-energy demonstration accelerator (LEDA) and discuss the integrated design of the full accelerator for the APT plant. LEDA's proton injector is under test and has produced more than 130 mA at 75 keV. Fabrication is proceeding on a 6.7- MeV, 8-meter-long RFQ, and detailed design is underway on coupled-cavity drift-tube linac (CCDTL) structures. In addition, detailed design and technology experiments are underway on medium-beta superconducting cavities to assess the feasibility of replacing the conventional (room-temperature copper) high-energy linac with a linac made of niobium superconducting RF cavities. (author)

  9. Combined Compute and Storage: Configurable Memristor Arrays to Accelerate Search

    Liu, Yang; Dwyer, Chris; Lebeck, Alvin R.

    2016-01-01

    Emerging technologies present opportunities for system designers to meet the challenges presented by competing trends of big data analytics and limitations on CMOS scaling. Specifically, memristors are an emerging high-density technology where the individual memristors can be used as storage or to perform computation. The voltage applied across a memristor determines its behavior (storage vs. compute), which enables a configurable memristor substrate that can embed computation with storage. T...

  10. Evidence and Search for Sterile Neutrinos at Accelerators

    W. C. Louis

    2013-01-01

    Full Text Available The LSND short-baseline neutrino experiment has published evidence for antineutrino oscillations at a mass scale of ~1 eV2. The MiniBooNE experiment, designed to test this evidence for oscillations at an order of magnitude higher neutrino energy and distance, observes excesses of events in both neutrino mode and antineutrino mode. While the MiniBooNE neutrino excess has a neutrino energy spectrum that is softer than expected from LSND, the MiniBooNE antineutrino excess is consistent with neutrino oscillations and with the LSND oscillation signal. When combined with oscillation measurements at the solar and atmospheric mass scales, assuming that the LSND and MiniBooNE signals are due to neutrino oscillations, these experiments imply the existence of more than three neutrino mass states and, therefore, one or more sterile neutrinos. Such sterile neutrinos, if proven to exist, would have a big impact on particle physics, nuclear physics, and astrophysics and would contribute to the dark matter of the universe. Future experiments under construction or proposed at Fermilab, ORNL, CERN, and in Japan will provide a definitive test of short-baseline neutrino oscillations and will have the capability of proving the existence of sterile neutrinos.

  11. Diffusive Shock Acceleration and Reconnection Acceleration Processes

    Zank, G. P.; Hunana, P.; Mostafavi, P.; Le Roux, J. A.; Li, Gang; Webb, G. M.; Khabarova, O.; Cummings, A.; Stone, E.; Decker, R.

    2015-12-01

    Shock waves, as shown by simulations and observations, can generate high levels of downstream vortical turbulence, including magnetic islands. We consider a combination of diffusive shock acceleration (DSA) and downstream magnetic-island-reconnection-related processes as an energization mechanism for charged particles. Observations of electron and ion distributions downstream of interplanetary shocks and the heliospheric termination shock (HTS) are frequently inconsistent with the predictions of classical DSA. We utilize a recently developed transport theory for charged particles propagating diffusively in a turbulent region filled with contracting and reconnecting plasmoids and small-scale current sheets. Particle energization associated with the anti-reconnection electric field, a consequence of magnetic island merging, and magnetic island contraction, are considered. For the former only, we find that (i) the spectrum is a hard power law in particle speed, and (ii) the downstream solution is constant. For downstream plasmoid contraction only, (i) the accelerated spectrum is a hard power law in particle speed; (ii) the particle intensity for a given energy peaks downstream of the shock, and the distance to the peak location increases with increasing particle energy, and (iii) the particle intensity amplification for a particular particle energy, f(x,c/{c}0)/f(0,c/{c}0), is not 1, as predicted by DSA, but increases with increasing particle energy. The general solution combines both the reconnection-induced electric field and plasmoid contraction. The observed energetic particle intensity profile observed by Voyager 2 downstream of the HTS appears to support a particle acceleration mechanism that combines both DSA and magnetic-island-reconnection-related processes.

  12. What can we expect from future accelerators

    This talk covers a general but highly subjective overview of the expectation for new accelerator development. An updated version of the Livingston chart demonstrates the exponential growth in time of the equivalent laboratory energy of accelerators. A similar Livingston chart pertaining only to electron-positron colliders shows an exponential growth but in the past only one technology - electron-positron storage rings - have been responsible for this development. The question addressed is whether the type of exponential growth reflected by these two charts can be sustained in the future

  13. Annotated bibliography on high-intensity linear accelerators

    A technical bibliography covering subjects important to the design of high-intensity beam transport systems and linear accelerators is presented. Space charge and emittance growth are stressed. Subject and author concordances provide cross-reference to detailed citations, which include an abstract and notes on the material. The bibliography resides in a computer database that can be searched for key words and phrases

  14. Accelerated Peer-Review Journal Usage Technique for Undergraduates

    Wallace, J. D.

    2008-01-01

    The internet has given undergraduate students ever-increasing access to academic journals via search engines and online databases. However, students typically do not have the ability to use these journals effectively. This often poses a dilemma for instructors. The accelerated peer-review journal usage (APJU) technique provides a way for…

  15. Neutrino mass and mixing, and non-accelerator experiments

    We review the current status of experimental knowledge about neutrinos derived from kinematic mass measurements, neutrino oscillation searches at reactors and accelerators, solar neutrinos, atmospheric neutrinos, and single and double beta decay. The solar neutrino results yield fairly strong and consistent indication that neutrino oscillations are occurring. Other evidence for new physics is less consistent and convincing

  16. Annotated bibliography on high-intensity linear accelerators. [240 citations

    Jameson, R.A.; Roybal, E.U.

    1978-01-01

    A technical bibliography covering subjects important to the design of high-intensity beam transport systems and linear accelerators is presented. Space charge and emittance growth are stressed. Subject and author concordances provide cross-reference to detailed citations, which include an abstract and notes on the material. The bibliography resides in a computer database that can be searched for key words and phrases.

  17. Improved Scatter Search Using Cuckoo Search

    Ahmed T.Sadiq Al-Obaidi

    2013-02-01

    Full Text Available The Scatter Search (SS is a deterministic strategy that has been applied successfully to some combinatorial and continuous optimization problems. Cuckoo Search (CS is heuristic search algorithm which is inspired by the reproduction strategy of cuckoos. This paper presents enhanced scatter search algorithm using CS algorithm. The improvement provides Scatter Search with random exploration for search space of problem and more of diversity and intensification for promising solutions. The original and improved Scatter Search has been tested on Traveling Salesman Problem. A computational experiment with benchmark instances is reported. The results demonstrate that the improved Scatter Search algorithms produce better performance than original Scatter Search algorithm. The improvement in the value of average fitness is 23.2% comparing with original SS. The developed algorithm has been compared with other algorithms for the same problem, and the result was competitive with some algorithm and insufficient with another.

  18. Accelerator business in Japan expanding

    Accelerators have become to be used increasingly in Japan in such fields as medicine, physics research and industry. This has caused stiff competition for market share by the manufacturers of accelerators. Electron beam accelerators for industrial use provide an indispensable means for adding values to products, for example, electric cables with incombustible insulators. Linear accelerators for the nondestructive inspection of nuclear components have been widely installed at equipment manufacturing plants. Active efforts have been exerted to develop small synchrotron radiation accelerators for next generation electronic industry. Cyclotrons for producing short life radioisotopes for medical diagnosis and electron beam accelerators for radiation therapy are also used routinely. The suppliers of accelerators include the companies manufacturing heavy electric machinery, heavy machinery and the engineering division of steelmakers. Accelerator physics is being formed, but universities do not yet offer the course regarding accelerators. Accelerator use in Japan and the trend of accelerator manufacturers are reported. (K.I.)

  19. Cavity characterization for general use in linear electron accelerators

    The main objective of this work is to is to develop measurement techniques for the characterization of microwave cavities used in linear electron accelerators. Methods are developed for the measurement of parameters that are essential to the design of an accelerator structure using conventional techniques of resonant cavities at low power. Disk-loaded cavities were designed and built, similar to those in most existing linear electron accelerators. As a result, the methods developed and the estimated accuracy were compared with those from other investigators. The results of this work are relevant for the design of cavities with the objective of developing linear electron accelerators. (author)

  20. Data mining technique for fast retrieval of similar waveforms in Fusion massive databases

    Fusion measurement systems generate similar waveforms for reproducible behavior. A major difficulty related to data analysis is the identification, in a rapid and automated way, of a set of discharges with comparable behaviour, i.e. discharges with 'similar' waveforms. Here we introduce a new technique for rapid searching and retrieval of 'similar' signals. The approach consists of building a classification system that avoids traversing the whole database looking for similarities. The classification system diminishes the problem dimensionality (by means of waveform feature extraction) and reduces the searching space to just the most probable 'similar' waveforms (clustering techniques). In the searching procedure, the input waveform is classified in any of the existing clusters. Then, a similarity measure is computed between the input signal and all cluster elements in order to identify the most similar waveforms. The inner product of normalized vectors is used as the similarity measure as it allows the searching process to be independent of signal gain and polarity. This development has been applied recently to TJ-II stellarator databases and has been integrated into its remote participation system