WorldWideScience

Sample records for abuse tnd dissemination

  1. Dissemination of Project Towards No Drug Abuse (TND): Findings From a Survey of Program Adopters

    Rohrbach, Louise A.; Gunning, Melissa; Grana, Rachel; Gunning, Gaylene; Sussman, Steve

    2010-01-01

    This study examines adoption and implementation decisions among organizations that purchased Project Towards No Drug Abuse from 2001 to 2004. Telephone interviews were conducted with 120 organizations nationwide. The most common reason for adopting the program was its evidence base. In schools, classroom teachers were more likely to deliver the program than other types of implementers, and in non-school organizations, prevention specialists and counselors were more common (p

  2. An Evaluation of Immediate Outcomes and Fidelity of a Drug Abuse Prevention Program in Continuation High Schools: Project towards No Drug Abuse (TND)

    Lisha, Nadra E.; Sun, Ping; Rohrbach, Louise A.; Spruijt-Metz, Donna; Unger, Jennifer B.; Sussman, Steve

    2012-01-01

    The present study provides an implementation fidelity, process, and immediate outcomes evaluation of Project Towards No Drug Abuse (TND), a drug prevention program targeting continuation high school youth (n = 1426) at risk for drug abuse. A total of 24 schools participated in three randomized conditions: TND Only, TND and motivational…

  3. Project Towards No Drug Abuse (TND): Needs Assessment of a Social Service Referral Telephone Program for High Risk Youth

    Sussman, Steve; SKARA, SILVANA; Pumpuang, Patchareeya

    2008-01-01

    The purpose of this study was to conduct a needs assessment of a potential social service resource telephone program component among high risk youth who received the Project Towards No Drug Abuse (TND) classroom-based program (approximately 1 year earlier). Results supported youths’ overwhelming receptiveness of a social service referral program. The vast majority of respondents indicated a strong desire for resource and referral information on vocational, educational, recreational, transport...

  4. Fidelity of Implementation in Project Towards No Drug Abuse (TND): A Comparison of Classroom Teachers and Program Specialists

    Rohrbach, Louise A.; Dent, Clyde W.; SKARA, SILVANA; Sun, Ping; Sussman, Steve

    2006-01-01

    This paper presents the results of an effectiveness trial of Project Towards No Drug Abuse [TND], in which we compared program delivery by regular classroom teachers and program specialists within the same high schools. Within 18 schools that were randomly assigned to the program or control conditions, health classrooms were assigned to program delivery by teachers or (outside) specialists. Classroom sessions were observed by pairs of observers to assess three domains of implementation fideli...

  5. Blending research and practice: an evolving dissemination strategy in substance abuse.

    Michel, Mary Ellen; Pintello, Denise A; Subramaniam, Geetha

    2013-01-01

    Substance abuse is a leading cause of death and disability throughout the world. The mission of the National Institute on Drug Abuse (NIDA) is to lead the United States in bringing the power of science to bear on drug abuse and addiction. This charge has two critical components: (a) strategic support of research across a broad range of disciplines and (b) rapid, effective dissemination of research results that can improve prevention and treatment efforts, with potential to inform policy. The NIDA Clinical Trials Network and the Blending Initiative are critical elements of this strategy, and the social work field is poised to use these resources to expand its role in the dissemination and implementation of NIDA's mission. PMID:23731421

  6. Tables of nuclear data (JENDL/TND-2012)

    Several numerical data (mass, level energy, spin and parity, abundance, mass excess, β-decay energy, and half-life) of nuclides were collected with each element into the “Tables of Nuclear Data (JENDL/TND-2012).” These tables are related to the “Chart of the Nuclides” published by Japanese Nuclear Data Committee and Nuclear Data Center of Japan Atomic Energy Agency (JAEA), and data of the nuclides synthesized in the chart. Moreover, new determinations are adopted instead of the values in ENSDF for half-lives of ground state of Se-79 and Sn-126. (author)

  7. Influence networks among substance abuse treatment clinics: implications for the dissemination of innovations

    Johnson, Kimberly; Quanbeck, Andrew; Maus, Adam; Gustafson, David H.; Dearing, James W.

    2015-01-01

    Understanding influence networks among substance abuse treatment clinics may speed the diffusion of innovations. The purpose of this study was to describe influence networks in Massachusetts, Michigan, New York, Oregon, and Washington and test two expectations, using social network analysis: (1) Social network measures can identify influential clinics; and (2) Within a network, some weakly connected clinics access out-of-network sources of innovative evidence-based practices and can spread th...

  8. Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions

    Becker, Sara J

    2015-01-01

    The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers a...

  9. Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions

    Becker, Sara J.

    2014-01-01

    The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed. PMID:25937710

  10. Abuse

    ... Paying for Care Insurance Medicare Medicare Part D Benefits Medicaid Tax Deductions & Credits Legal Matters Planning Ahead Legal Documents alz.org » Caregiver Center » Safety » Abuse Text size: A A A Special Situations First Responders Traveling In a Disaster Abuse Find your local Chapter ...

  11. Disseminated Cysticercosis

    Park, Soo Yong; Kong, Min Ho; Kim, Jung hee; Song, Kwan Young

    2011-01-01

    Disseminated cysticercosis is a rare form of cysticercosis in which the cysticerci spread out through the whole body. We report the first case of a 39-year-old Mongolian with disseminated cysticercosis. He visited our hospital with generalized tonic-clonic seizure. After extensive investigation from brain computed tomography (CT), spine magnetic resonance imaging (MRI), whole body MRI and pathologic biopsy, he was diagnosed as having cysticercosis involving the brain, subcutaneous tissue, and...

  12. Ultra-pure soft water ameliorates atopic skin disease by preventing metallic soap deposition in NC/Tnd mice and reduces skin dryness in humans.

    Tanaka, Akane; Matsuda, Akira; Jung, Kyungsook; Jang, Hyosun; Ahn, Ginnae; Ishizaka, Saori; Amagai, Yosuke; Oida, Kumiko; Arkwright, Peter D; Matsuda, Hiroshi

    2015-09-01

    Mineral ions in tap water react with fatty acids in soap, leading to the formation of insoluble precipitate (metallic soap) on skin during washing. We hypothesised that metallic soap might negatively alter skin conditions. Application of metallic soap onto the skin of NC/Tnd mice with allergic dermatitis further induced inflammation with elevation of plasma immunoglobulin E and proinflammatory cytokine expression. Pruritus and dryness were ameliorated when the back of mice was washed with soap in Ca2+- and Mg2+-free ultra-pure soft water (UPSW). Washing in UPSW, but not tap water, also protected the skin of healthy volunteers from the soap deposition. Furthermore, 4 weeks of showering with UPSW reduced dryness and pruritus of human subjects with dry skin. Washing with UPSW may be therapeutically beneficial in patients with skin troubles. PMID:25739908

  13. DISSEMINATED CYSTICERCOSIS

    Nirmala

    2013-04-01

    Full Text Available INTRODUCTION: Cysticercosis is a systemic illness caused by disse mination of the larval form of the pork tapeworm, Taenia solium. Cysticerci may be found in almost any tissue. The most frequently reported locations are skin, skeletal mus cle, heart, eye, and the central nervous system . [1] FNAC and Biopsy of these lesions can show the larval structures and are diagnostic of cysticercosis. Identification of the parasitic cells give a important clue to the diagnosis of cysticercosis. We present this case of disseminated cysticercosis with ultrasonographic, cytology and histopathological correlation.

  14. Elder Abuse and Substance Abuse

    Navigation Physical Abuse Sexual Abuse Domestic Violence Psychological Abuse Financial Abuse Neglect Critical Issues The Role of Culture in Elder ... factor in all types of elder abuse, including physical mistreatment, emotional abuse, financial exploitation, and neglect. It is also a ...

  15. Elder Abuse

    ... nursing home . Types of Abuse There are many types of abuse: Physical abuse happens when someone causes bodily harm by hitting, pushing, or slapping. Emotional abuse , sometimes called psychological abuse, can include a caregiver saying hurtful words, ...

  16. Physical Abuse

    ... Additional Resources Return to: What is Elder Abuse? Physical Abuse Physical abuse is physical force or violence that results in ... may be acquaintances, sons, daughters, grandchildren, or others. Physical abuse that is perpetrated by spouses or intimate partners ...

  17. Sexual Abuse

    Navigation Physical Abuse Sexual Abuse Domestic Violence Psychological Abuse Financial Abuse Neglect Critical Issues What Communities Can Do The Role ... Abuse and Neglect Ramsey-Klawsnik, H. (1996). Assessing physical and sexual abuse in health care settings. In L.A. Baumhover & S. ...

  18. Asymptomatic Disseminated Cysticercosis

    Vaidya, Ashima; Singhal, Suman; Dhall, Sonia; Manohar, Ashish; Mahajan, Harsh

    2013-01-01

    Cysticercosis is a common problem world wide. However, disseminated cysticercosis is rare. Still rarer is asymptomatic disseminated cysticercosis. We are reporting here a rare case of asymptomatic disseminated cysticercosis which involved brain, face, orbit, lungs, heart, pancreas and spleen in a young Nigerian male, who sought medical attention for dysphagia which was diagnosed as achalasia cardia. Despite widespread dissemination of cysticercosis which involves multiple organs, the individu...

  19. DOREMI - Dissemination Plan

    Lupi??ez-Villanueva, Francisco; Vozzi, Federico; Rial, Michela; Morales, Aurora; Parodi, Oberdan; Ferro, Erina; Fortunati, Luigi; Palumbo, Filippo

    2014-01-01

    The deliverable D7.1 "Dissemination plan" aims at formulating the project's dissemination strategy and plan, identifying the specific approaches best suited for contact and interaction with target groups, considering both new (e.g. internet exploitation; cross-posting, cycling references, etc.) and traditional (e.g. press release, newsletters, conferences, etc.) dissemination avenues. The report starts with the identification of the key stakeholders of the projects and the main dissemination ...

  20. Elder Abuse

    ... facilities or nursing homes. The mistreatment may be Physical, sexual, or emotional abuse Neglect or abandonment Financial abuse - stealing of money or belongings Possible signs of elder abuse include unexplained bruises, burns, ...

  1. Child Abuse

    ... puts a child at risk of harm. Child abuse can be physical, sexual or emotional. Neglect, or not providing for a child's needs, is also a form of abuse. Most abused children suffer greater emotional than physical ...

  2. Dissemination beyond publication.

    2015-07-01

    The mantra 'publish or perish' has meant disseminating work in peer-reviewed literature. Digital has changed the way readers access content and has created a need to disseminate work widely for maximum impact. Research metrics used internationally to evaluate research are now based on the number of citations of a paper. PMID:26168805

  3. Dissemination and Exploitation Strategy

    Badger, Merete; Monaco, Lucio; Fransson, Torsten; Farinetti, Laura; Corno, Fulvio; Vercoulen, Frank

    Technology in Sweden, Politecnico di Torino in Italy, and Eindhoven University of Technology in the Netherlands. The project is partially funded by the European Commission under the 7th Framework Programme (project no. RI-283746). This report describes the final dissemination and exploitation strategy for...... project Virtual Campus Hub. A preliminary dissemination and exploitation plan was setup early in the project as described in the deliverable D6.1 Dissemination strategy paper - preliminary version. The plan has been revised on a monthly basis during the project’s lifecycle in connection with the virtual...

  4. Drug Abuse

    ... as drugged driving, violence, stress, and child abuse. Drug abuse can lead to homelessness, crime, and missed work or problems with keeping a job. It harms unborn babies and destroys families. There are different types of treatment for drug abuse. But the best is to prevent drug ...

  5. Elder abuse

    1999-01-01

    Elder abuse takes many forms and occurs in a variety of settings; it is both under-recognised and under-reported. Despite a lack of statutory guidelines or legislation, effective management is possible. More could be done to recognise abuse, and healthcare workers need to be vigilant, paying attention to both the circumstances in which abuse occurs and its warning signs.

  6. Child abuse

    Child abuse is common in most, if not all, Western nations; it probably occurs worldwide. It may be a major factor in the increase in violence throughout much of the world. Radiologists who treat children should think of the possibilitys of abuse whenever they diagnose a fracture, intracranial bleed, ar visceral injury, especially when the history is not compatible with their findings. Metaphyseal 'corner' fractures in infants usually are caused by abuse. Less than 20% of abused children, however, present injuries that can be recognized by radiologic techniques. Consequently normal roentgenograms, nuclear medicine scans, ultrasound studies, and computed tomograms do not exclude child abuse. (orig.)

  7. Extensive disseminated cysticercosis

    Sujay Khandpur; Sunil Kumar Kothiwala; Binamra Basnet; Rattan Nangia; H A Venkatesh; Raju Sharma

    2014-01-01

    Cysticercosis, especially neurocysticercosis, is a major public health problem in India. We report an unusual case of disseminated cysticercosis with extensive infiltration of the skin, central nervous system, skeletal muscles, eye, lung, and heart. A patient with extensive cutaneous cysticercosis must be thoroughly investigated for widespread internal organ involvement.

  8. 75 FR 42102 - National Institute on Drug Abuse; Notice of Closed Meeting

    2010-07-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel, Research Dissemination (1143). Date..., Contract Review Specialist, Office of Extramural Affairs, National Institute on Drug Abuse, NIH, DHHS,...

  9. How to Handle Abuse

    ... abuse: physical, sexual, verbal or emotional, and neglect. Physical abuse: Physical abuse is hitting hard with a hand or an ... choking, painful grabbing, and kicking also can be physical abuse. Sexual abuse: Your body has private parts. These ...

  10. Inhalant Abuse

    ... she is likely to try other kinds of drugs, especially alcohol and marijuana. Symptoms How can I tell if my child is abusing inhalants? It can be hard to recognize the signs of inhalant abuse. Teenagers who use inhalants may have some of the ...

  11. Abusive Relationships

    ... leaving. Where to Get Help Ending abuse and violence in teen relationships is a community effort with plenty of ... other ways to get involved in making sure dating abuse doesn’t happen to people in your school. Reviewed by: D'Arcy Lyness, PhD Date reviewed: May ... For Teens For Kids For Parents MORE ON THIS TOPIC ...

  12. Child Abuse and Domestic Abuse

    ... Traumatic Stress Disorder Reporting Domestic Abuse Reporting Suspected Child Abuse or Neglect Traumatic Brain Injury Family & Relationships There’s more to a military family than moving and deployments — take us along through each phase of your military ... Care and Youth Programs Parenting Military Youth on ...

  13. Peer abuse

    Alikaşifoğlu, Müjgan

    2011-01-01

    Peer abuse is commonly seen as bullying behaviors The most common definition of bullying used in the literature was formulated by Dan nbsp;Olweus According to Olweus bullying is an aggressive behavior that: a is intended to cause harm or distress b occurs repeatedly over nbsp;time and c occurs in a relationship in which there is an imbalance of power Peer abuse shares many characteristics with other types of nbsp;abuse namely child maltreatment and domestic violence Bullying behaviors may be ...

  14. Preventing Child Abuse and Neglect

    ... Abuse & Neglect Fatalities Preventing Child Abuse & Neglect National Child Abuse Prevention Month Overview Promoting Child & Family Well-Being Public ... Abuse & Neglect Preventing Child Abuse & Neglect Resources on child abuse prevention, protecting children from risk of abuse, and strengthening ...

  15. Drug abuse

    This paper reports that this study used SPECT to examine patients who have abused drugs to determine whether SPECT could identify abnormalities and whether these findings have clinical importance. Fifteen patients with a history of substance abuse (eight with cocaine, six with amphetamine, and one with organic solvent) underwent SPECT performed with a triple-headed camera and Tc-99m HMPAO both early for blood flow and later for functional information. These images were then processed into a 3D videotaped display used in group therapy. All 15 patients had multiple areas of decreased tracer uptake peppered throughout the cortex but mainly affecting the parietal lobes, expect for the organic solvent abuser who had a large parietal defect. The videotapes were subjectively described by a therapist as an exceptional tool that countered patient denial of physical damage from substance abuse. Statistical studies of recidivism between groups is under way

  16. Acute Disseminated Encephalomyelitis

    Kambiz Sotoudeh

    Full Text Available Acute disseminated encephalomyelitis (ADEM is an acute, inflammatory, monophasic, demyelinating and immune-mediated disorder of central nervous system; occurs mostly in children after systemic viral infections or vaccinations. Acute polysymptomatic neurologic signs such as encephalopathy, paralysis of limbs, cranial nerve involvement, ataxia and optic neuritis are common manifestations. Brain magnetic resonance imaging study is essential for diagnosis and enabling prompt diagnosis and treatment. Evidence of multifocal lesions of demyelination in subcortical white matter are seen. They are usually bilateral and asymmetrical. Treatment optins have included steroids, immunoglobulins, and plasmapheresis. ADEM is treatable and prognosis is good.

  17. Delusions of Disseminated Fungosis

    Ian Gassiep

    2014-01-01

    Full Text Available Introduction. Delusional infestation is a rare monosymptomatic hypochondriacal psychosis according to The Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association, 2013. It can be a primary disorder or associated with an underlying psychological or physical disorder. It commonly presents as delusional parasitosis, and less than 1% may be fungi related. We present this case as it is a rare presentation of a rare condition. Case Presentation. Our patient is a 60-year-old Caucasian man who presented with a 7-year history of delusional infestation manifested as a disseminated fungal infection. He had previously been reviewed by multiple physicians for the same with no systemic illness diagnosed. After multiple reviews and thorough investigation we diagnosed him with a likely delusional disorder. As is common with this patient cohort he refused psychiatric review or antipsychotic medication. Conclusion. A delusion of a disseminated fungal infestation is a rare condition. It is exceedingly difficult to treat as these patients often refuse to believe the investigation results and diagnosis. Furthermore, they either refuse or are noncompliant with treatment. Multidisciplinary outpatient evaluation may be the best way to allay patient fears and improve treatment compliance.

  18. AIDS defining disease: Disseminated cryptococcosis

    Roshan Anupama

    2006-01-01

    Full Text Available Disseminated cryptococcosis is one of the acquired immune deficiency syndrome defining criteria and the most common cause of life threatening meningitis. Disseminated lesions in the skin manifest as papules or nodules that mimic molluscum contagiosum (MC. We report here a human immunodeficiency virus positive patient who presented with MC like lesions. Disseminated cryptococcosis was confirmed by India ink preparation and histopathology. The condition of the patient improved with amphotercin B.

  19. Disseminated Mastocytosis in a Dog

    Pukay, B. P.

    1984-01-01

    A 13 year old neutered female crossbred Poodle with disseminated mastocytosis was treated with systemic glucocorticoids and antibiotics. The diagnosis was made postmortem, based on histopathological findings.

  20. Disseminated intravascular coagulation.

    Gando, Satoshi; Levi, Marcel; Toh, Cheng-Hock

    2016-01-01

    Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by widespread intravascular activation of coagulation that can be caused by infectious insults (such as sepsis) and non-infectious insults (such as trauma). The main pathophysiological mechanisms of DIC are inflammatory cytokine-initiated activation of tissue factor-dependent coagulation, insufficient control of anticoagulant pathways and plasminogen activator inhibitor 1-mediated suppression of fibrinolysis. Together, these changes give rise to endothelial dysfunction and microvascular thrombosis, which can cause organ dysfunction and seriously affect patient prognosis. Recent observations have pointed to an important role for extracellular DNA and DNA-binding proteins, such as histones, in the pathogenesis of DIC. The International Society on Thrombosis and Haemostasis (ISTH) established a DIC diagnostic scoring system consisting of global haemostatic test parameters. This scoring system has now been well validated in diverse clinical settings. The theoretical cornerstone of DIC management is the specific and vigorous treatment of the underlying conditions, and DIC should be simultaneously managed to improve patient outcomes. The ISTH guidance for the treatment of DIC recommends treatment strategies that are based on current evidence. In this Primer, we provide an updated overview of the pathophysiology, diagnosis and management of DIC and discuss the future directions of basic and clinical research in this field. PMID:27250996

  1. Acute disseminated encephalomyelitis.

    Murthy J

    2002-07-01

    Full Text Available Acute disseminated encephalomyelitis (ADEM is an uncommon inflammatory demyelinating disease of the central nervous system. The true incidence of the disease in India is undetermined and is likely to be more frequent than reported, as the common antecedent events, exanthematous fevers and Semple antirabies vaccination, which predispose to ADEM, are still prevalent. The existing evidence suggests that ADEM results from a transient autoimmune response towards myelin or other self-antigens, possibly via molecular mimicry, or by non-specific activation of auto-reactive T cell clones. ADEM is a monophasic illness with favourable long-term outcome. Involvement of neuroaxis is variable and can be diffuse or multifocal and site restricted. Magnetic resonance imaging (MRI is highly sensitive in detecting white matter lesions and the lesions described are rather extensive and subcortical in location. Involvement of the deep gray matter, particularly basal ganglia, is more frequent. Oligoclonal bands in CSF are usually absent. No therapy has been established by controlled trials in ADEM. Use of high-dose methylprednisolone, plasma exchange, and IVIG are based on the analogy of the pathogenesis of ADEM with that of multiple sclerosis (MS. Differentiation of ADEM from the first attack of MS is important from prognostic as well as therapeutic point of view. However, in the absence of biological marker, at times differentiation of ADEM from the initial presentation of MS may not be possible even by combination of clinical, CSF analysis, and MRI. This differentiation is more relevant to India where the incidence of MS is low.

  2. How Is Disseminated Intravascular Coagulation Treated?

    ... the NHLBI on Twitter. How Is Disseminated Intravascular Coagulation Treated? Treatment for disseminated intravascular coagulation (DIC) depends ... and treat the underlying cause. Acute Disseminated Intravascular Coagulation People who have acute DIC may have severe ...

  3. An Empirical Case Study of a Child Sexual Abuse Prevention Initiative in Georgia

    Schober, Daniel J.; Fawcett, Stephen B.; Thigpen, Sally; Curtis, Anna; Wright, Renee

    2012-01-01

    Objective: This empirical case study describes Prevent Child Abuse Georgia's effort to prevent child sexual abuse (CSA) by educating communities throughout the state on supporting preventive behaviour. The initiative consisted of three major components: (1) dissemination of CSA prevention messages and materials; (2) a statewide helpline that…

  4. Child Sexual Abuse

    Sexual abuse is one form of child abuse. It includes a wide range of actions between a child ... to children or pressuring them for sex is sexual abuse. Using a child for pornography is also sexual ...

  5. Prevent Child Abuse America

    ... call the police . Crisis and support contacts For Child Abuse Reporting Numbers in your State please visit: Child ... suspected child abuse and neglect. Parent Resources Prevent Child Abuse America (800) CHILDREN A resource for tips, referrals, ...

  6. What is Elder Abuse?

    ... to another, but broadly defined, abuse may be: Physical Abuse —inflicting physical pain or injury on a senior, ... abrasions, and burns may be an indication of physical abuse, neglect, or mistreatment. Unexplained withdrawal from normal activities, ...

  7. D5.1 Dissemination Plan

    Buus, Lillian; Ryberg, Thomas; Eleftheriou, Paraskevi;

    2009-01-01

    This deliverable describes the detailed dissemination plan of the EATrain2 consortium. It includes all important aspects of planned dissemination activities, defines dissemination phases and presents material and tools prepared in order to disseminate information on the EATrain2 solution. It aims...

  8. Data Dissemination in Opportunistic Networks

    Ciobanu, Radu

    2012-01-01

    Mobile devices integrating wireless short-range communication technologies make possible new applications for spontaneous communication, interaction and collaboration. An interesting approach is to use collaboration to facilitate communication when mobile devices are not able to establish direct communication paths. Opportunistic networks, formed when mobile devices communicate with each other while users are in close proximity, can help applications still exchange data in such cases. In opportunistic networks routes are built dynamically, as each mobile device acts according to the store-carry-and-forward paradigm. Thus, contacts between mobile devices are seen as opportunities to move data towards destination. In such networks data dissemination is done using forwarding and is usually based on a publish/subscribe model. Opportunistic data dissemination also raises questions concerning user privacy and incentives. Such problems are addressed di?erently by various opportunistic data dissemination techniques. ...

  9. Disseminated tuberculosis with rare involvements

    We report a case of disseminated tuberculosis involving the middle ear, the central nervous system, the spine and the lung. The tuberculous epidural abscess and otomastoiditis don't have any specific imaging features. But their coexistence with an other tuberculous involvement might suggest their tuberculous nature. The epidural abscess may result from direct extension from otomastoiditis. (authors)

  10. Disseminating and Using Research Reports.

    Overs, Robert P.; Trotter, Ann B.

    The authors offer some practical guidelines in four areas of rehabilitation research information dissemination: (1) filing and retrieval problems; (2) level and styles of writing, listing, abstracting, summarizing, and reconceptualizing; (3) profiling the average practitioner-consumers; and (4) leveling attitudinal barriers. Filing and retrieval…

  11. Childhood sexual abuse.

    Evrim Aktepe

    1993-01-01

    Sexual abuse is defined as use of child or adolescent by the adults for satisfying of sexual urges and needs with forcing, threatening or tricking. Sexual abuse can be in the form of sexual abuse without touch, sexual touch, interfemoral intercourse, sexual penetration, and sexual exploitation. The prevalence of sexual abuse is reported as 10-40%. It is seen in female four times more than in males. Abusers are frequently male, only 5-15% of them are female. The abuse by females is usually tow...

  12. Childhood Sexual Abuse

    Aktepe, Evrim

    2009-01-01

    Sexual abuse is defined as use of child or adolescent by the adults for satisfying of sexual urges and needs with forcing, threatening or tricking. Sexual abuse can be in the form of sexual abuse without touch, sexual touch, interfemoral intercourse, sexual penetration, and sexual exploitation. The prevalence of sexual abuse is reported as 10-40%. It is seen in female four times more than in males. Abusers are frequently male, only 5-15% of them are female. The abuse by females is usually tow...

  13. Childhood Sexual Abuse

    Evrim Aktepe

    2009-08-01

    Full Text Available Sexual abuse is defined as use of child or adolescent by the adults for satisfying of sexual urges and needs with forcing, threatening or tricking. Sexual abuse can be in the form of sexual abuse without touch, sexual touch, interfemoral intercourse, sexual penetration, and sexual exploitation. The prevalence of sexual abuse is reported as 10-40%. It is seen in female four times more than in males. Abusers are frequently male, only 5-15% of them are female. The abuse by females is usually towards male child. Thirty-fifty percent of abuse cases among child and adolescent are outside the family including strangers or familiar person. Some features of abusers are introvert personality, pedophilic and antisocial personality. Most of the abusers have a history of sexual abuse or aggression during childhood. Sexual intercourse between two people who are not allowed to marry by law is called as incest. Family pattern of incest is defined globally as disorganized and dysfunctional. The most commonly reported familial pattern is rigid and patriarchal family pattern with a harsh father using force quite frequently. The clinical features and impacts of the sexual abuse on the child varies according to the relation between abusers and the child, form of abuse, duration of abuse, presence of physical assault, developmental phase, child age and psychological development before the abuse. Sexual abuse history may result in psychiatric disorders including anxiety, depression, substance dependence, suicide act, borderline personality disorder, posttraumatic stress disorder. Abuse negatively affects interpersonal relationships and self esteem of abused individuals. Several studies reported close association between risky sexual behaviors in adulthood and a history of of sexual abuse during childhood. Four traumatic dynamics including traumatic sexuality with abuse, feeling of betrayal, weakness, and stigmatization exist in childhood abuse. Trauma can cause

  14. Cough and Cold Medicine Abuse

    ... and Cold Medicine Abuse DrugFacts: Cough and Cold Medicine Abuse Email Facebook Twitter Revised May 2014 Some ... diverted for abuse. How Are Cough and Cold Medicines Abused? Cough and cold medicines are usually consumed ...

  15. Knowledge dissemination: a core mission

    2011-01-01

    It’s been a year since the CERN Council approved our policy on intellectual property management, so I’d like to take a look at what we’ve achieved since then. In short, a great deal. We’ve moved away from a fairly unregulated approach towards a well balanced and clearly defined system built around sound intellectual property management designed to deliver maximum dissemination and benefit for society from CERN innovation. It’s a move that I celebrate and fully support.   In 2009, CERN signed two partnership agreements to develop CERN technologies, two commercial licenses and eleven R&D licenses. Last year, the figures were six partnership agreements, five commercial licenses and twenty R&D licenses, indicating a real increase in dissemination efforts. From 2009 to 2010, however, the number of new technologies that were identified and disclosed hardly changed: nine in 2009, ten in 2010. These numbers are good, but we must improve, particu...

  16. Skin manifestations of child abuse

    Ermertcan Aylin; Ertan Pelin

    2010-01-01

    Child abuse is a major public health problem all over the world. There are four major types of abuse: physical abuse, sexual abuse, emotional abuse and neglect. The most common manifestations of child abuse are cutaneous and their recognition; and differential diagnosis is of great importance. Clinicians, especially dermatologists, should be alert about the skin lesions of child abuse. In the diagnosis and management of child abuse, a multidisciplinary approach with ethical and legal procedur...

  17. Data Dissemination in the Wild

    Vingelmann, Peter; Pedersen, Morten Videbæk; Heide, Janus;

    2012-01-01

    This paper investigates the problem of efficient data dissemination in Mobile Ad hoc NETworks (MANETs) with high mobility. A testbed is presented; which provides a high degree of mobility in experiments. The testbed consists of 10 autonomous robots with mobile phones mounted on them. The mobile p....... The measurement results collected from the testbed are presented, and the performance of the proposed strategy is compared to a reference strategy that is based on TCP unicast connections....

  18. Child abuse - physical

    ... this page: //medlineplus.gov/ency/article/001552.htm Child abuse - physical To use the sharing features on this page, please enable JavaScript. Physical child abuse is a serious problem. Here are some facts: ...

  19. Alcoholism and Alcohol Abuse

    ... their drinking causes distress and harm. It includes alcoholism and alcohol abuse. Alcoholism, or alcohol dependence, is a disease that causes ... groups. NIH: National Institute on Alcohol Abuse and Alcoholism

  20. Prescription Drug Abuse

    ... a drug abuser aggressive or paranoid. Although stimulant abuse might not lead to physical dependence and withdrawal, the feelings these drugs give people can cause them to use the drugs more and more ...

  1. Abuse during Pregnancy

    ... partner may try to hurt your body. This physical abuse can include hitting, slapping, kicking, choking, pushing or ... your unborn baby in grave danger. During pregnancy, physical abuse can lead to miscarriage and vaginal bleeding . It ...

  2. Prescription Drug Abuse

    ... what the doctor prescribed, it is called prescription drug abuse. It could be Taking a medicine that ... purpose, such as getting high Abusing some prescription drugs can lead to addiction. These include narcotic painkillers, ...

  3. Who Owns Child Abuse?

    Gerald Cradock

    2014-11-01

    Full Text Available Expectations of contemporary child protection apparatuses are strongly influenced by beliefs inherited from the nineteenth century child rescue movement. In particular, the belief that child abuse determination is obvious. However, this assumption fails to make a distinction between nineteenth century’s emphasis on impoverished environments and the twentieth century introduction of the pathological child abuser. Moreover, the proliferation of kinds of child abuse, and the need to distinguish child abusers from non-abusers, means knowledge is now spread across an array of disciplines and professions, which necessarily destabilizes the definition of child abuse. The increasing exposure of alternate care systems as potentially abusive has similarly destabilized the old common sense solution to neglected children—namely removal. Finally, as uncertainty increases, and definitions become more divergent, the question of what child abuse is, and what should be done about it, becomes increasingly politicized.

  4. Preventing Child Abuse

    Alvy, Kerby T.

    1975-01-01

    Focuses on two major and general approaches to analyzing the problems of child abuse; briefly discusses the prevention implications; deals with the individual physical abuse of children, with particular emphasis on the relationship between theoretical formulations of the causes of individual physical abuse and preventative programs; and, finally,…

  5. Child Abuse and Neglect

    Yaşar Tıraşçı; Süleyman Gören

    2007-01-01

    Child abuse is the physical or psychological maltreatment of a child by an adult. In recent years, the affinity and aware of child abuse have been increased in Turkey. But, it is not enough. The purpose of this article was to defined child abuse and to attract attention of population and medical worker.

  6. Drug and Substance Abuse

    ... are common in later life. The Most Common Types of Drug and Substance Abuse Prescription and Over-the-Counter Medications Abuse Among ... older population than in younger people. But, other types of substance abuse, such as inappropriate use of prescription and over- ...

  7. Dissemination stability and phase noise specification of fiber-cascaded RF frequency dissemination

    Gao, C.; Wang, B.; Zhu, Xi; Yuan, Y. B.; Wang, L. J.

    2015-01-01

    Over the past decade, fiber based frequency dissemination has achieved significant progresses in following aspects. To study the dissemination stability and phase noise specifications of the fiber-cascaded RF frequency dissemination system, we perform a lab-top experiment using three sets of RF modulated frequency dissemination systems. They are linked by 50 km + 50 km +45 km fiber spools. The dissemination stabilities of each segments and whole system are measured simultaneously. After that,...

  8. Child Abuse in India

    Mohammad Reza Iravani

    2011-01-01

    Child abuse is harm to, or neglect of, a child by another person, whether adult or child. Child abuse happens in all cultural, ethnic, and income groups. Child abuse can be physical, emotional - verbal, sexual or through neglect. Abuse may cause serious injury to the child and may even result in death. A problem that is only beginning to come into light in India rape, sexual abuse, and sexual harassment are worldwide issues of gender violence. There is very little research done in this area i...

  9. Inhalant Abuse and Dextromethorphan.

    Storck, Michael; Black, Laura; Liddell, Morgan

    2016-07-01

    Inhalant abuse is the intentional inhalation of a volatile substance for the purpose of achieving an altered mental state. As an important, yet underrecognized form of substance abuse, inhalant abuse crosses all demographic, ethnic, and socioeconomic boundaries, causing significant morbidity and mortality in school-aged and older children. This review presents current perspectives on epidemiology, detection, and clinical challenges of inhalant abuse and offers advice regarding the medical and mental health providers' roles in the prevention and management of this substance abuse problem. Also discussed is the misuse of a specific "over-the-counter" dissociative, dextromethorphan. PMID:27338970

  10. Child sexual abuse in Ireland: A synthesis of two studies

    O'Reilly, Gary; Carr, Alan.

    2004-01-01

    Professionals involved in working with victims or perpetrators of childhood sexual abuse (CSA) require a basic understanding of the nature of this problem in our society. The purpose of this article is to aid such an understanding from an Irish perspective by attempting a synthesis of two excellent and comprehensive research studies. Although these studies first appeared in the literature some time ago their findings remain relevant and in need of dissemination. peer-reviewed

  11. Maltreated and abused children

    HOUFOVÁ, Jana

    2011-01-01

    According to the statistics there are forty thousand of battered and abused children in the Czech Republic. Maltreatment and abuse are not revealed in most cases and thus they accompany the children during their whole childhood. The reason is that children cannot defend themselves. The maltreatment or the abuse of a child is revealed only if somebody from the child?s neighbourhood observes anything suspicious and decides to report it, which is both a moral and a legal obligation. A person, wh...

  12. Child abuse and neglect

    Kiran, K

    2011-01-01

    Child abuse and neglect are important public health problems and recent estimates of their prevalence suggest that they are considerably more common than had hitherto been realized. Intervening to change parenting practices may, however, be important in their treatment. Despite their frequent occurrence among dental patients, neglect is the least known and identified type of abuse. The present case reports a 3-year-old girl suffering from abuse and neglect. The girl had dental neglect and als...

  13. Who Owns Child Abuse?

    Gerald Cradock

    2014-01-01

    Expectations of contemporary child protection apparatuses are strongly influenced by beliefs inherited from the nineteenth century child rescue movement. In particular, the belief that child abuse determination is obvious. However, this assumption fails to make a distinction between nineteenth century’s emphasis on impoverished environments and the twentieth century introduction of the pathological child abuser. Moreover, the proliferation of kinds of child abuse, and the need to distinguis...

  14. DISSEMINATING AGRICULTURAL INFORMATION THROUGH THE INTERNET: INDONESIAN CENTER FOR AGRICULTURAL LIBRARY AND TECHNOLOGY DISSEMINATION EXPERIENCE

    Bambang Winarko

    2011-12-01

    Full Text Available The Indonesian Center for Library and Technology Dissemination (ICALTD has a duty to disseminate agricultural information to researchers, extension workers, academicians, and other general users. Previously, the dissemination was based on printed publications. However, along with the penetration and development of the internet, the method of dissemination has changed to ITC-based dissemination. CD/VCD and internet technology application plays an important role in ICALTD’s dissemination of agricultural information. The involvement of internet technology in the dissemination of agricultural information ranges from purchasing online electronic journals for the main library collection to electronic-based processing and internet-based services. Efforts to educate stakeholders, such as administrators, content providers, and users, are carried out to ensure the successful dissemination of agricultural information.

  15. Child Sexual Abuse

    HROBAŘOVÁ, Petra

    2008-01-01

    My thesis deals with the problems of sexual abuse of children. It is divided into nine chapters, each of which has a subhead. In the first part, I focused on the term of child sexual abuse. In the second part, I focused on the problem of sexual abuse of children by family members. In the third part, I explained the term of commercial sexual violence committed against children. In the fourth part, I focused on the victims of sexual abuse and in the following part, I focused on the perpetrators...

  16. SUBSTANCE ABUSE IN INDIA

    Bano Rubeena

    2009-12-01

    Full Text Available The epidemic of substance abuse in young generation has assumed alarming dimensions in India. Changing cultural values, increasing economic stress and dwindling supportive bonds are leading to initiation into substance use. Cannabis, heroin, and Indian-produced pharmaceutical drugs are the most frequently abused drugs in India. Drug use, misuse or abuse is also primarily due to the nature of the drug abused, the personality of the individual and the addict’s immediate environment. The processes of industrialization, urbanization and migration have led to loosening of the traditional methods of social control rendering an individual vulnerable to the stresses and strains of modern life.

  17. Elder Abuse and Neglect

    Muge Gulen

    2013-06-01

    Full Text Available Abuse and neglect are preventable societal problems that influence elderly individuals physically, spiritually and socially. Elder abuse is neglected for many years and is a growing problem all over the world. The aim of this article is to review the evaluation of elderly individuals who are exposed to abuse and neglect with systematic detailed history and physical examination and to describe individual, familial, and social measures that should be taken to prevent these abuses. [Archives Medical Review Journal 2013; 22(3.000: 393-407

  18. Substance Abuse in the Military

    ... DrugFacts » Substance Abuse in the Military DrugFacts: Substance Abuse in the Military Email Facebook Twitter Revised March ... alcohol and tobacco use, and especially prescription drug abuse, are much more prevalent and are on the ...

  19. Substance abuse and rehabilitation: responding to the global burden of diseases attributable to substance abuse

    Li-Tzy Wu

    2010-11-01

    Full Text Available Li-Tzy Wu*Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, NC, USA *Li-Tzy Wu is the Editor-in-Chief of Substance Abuse and RehabilitationAbstract: Alcohol, tobacco, and illegal drug use are pervasive throughout the world. Substance use problems are among the major contributors to the global disease burden, which includes disability and mortality. The benefits of treatment far outweigh the economic costs. Despite the availability of treatment services, however, the vast majority of people with substance use disorders do not seek or use treatment. Barriers to and unmet need for evidence-based treatment are widespread even in the United States. Women, adolescents, and young adults are especially vulnerable to adverse effects from substance abuse, but they face additional barriers to getting evidence-based treatment or other social/medical services. Substance use behaviors and the diseases attributable to substance use problems are preventable and modifiable. Yet the ever-changing patterns of substance use and associated problems require combined research and policy-making efforts from all parts of the world to establish a viable knowledge base to inform for prevention, risk-reduction intervention, effective use of evidence-based treatment, and rehabilitation for long-term recovery. The new international, open-access, peer-reviewed Substance Abuse and Rehabilitation (SAR journal strives to provide an effective platform for sharing ideas for solutions and disseminating research findings globally. Substance use behaviors and problems have no boundaries. The journal welcomes papers from all regions of the world that address any aspect of substance use, abuse/dependence, intervention, treatment, and policy. The “open-access” journal makes cutting edge knowledge freely available to practitioners and researchers worldwide, and this is particularly important for addressing

  20. Disseminated candidiasis 18 years after renal transplantation

    Bismay, K.; Mathew, A.; R. Rajesh; Kurian, G.; Unni, V. N.; Kavita, R. D.; Sreehari, S.

    2012-01-01

    Although mucocutaneous candidiasis is a common infection in renal transplant recipients, disseminated candidiasis is rare. Candida pnemonia causing miliary mottling on X-ray chest with the central nervous system involvement is still rarer. We report an unusual case with disseminated candidiasis that presented 18 years after renal transplantation and improved on conventional antifungal therapy; the relevant literature is reviewed.

  1. Subarachnoid disseminative hemangiopericytoma of the spinal cord

    LIN Guo-zhong; WANG Zhen-yu; LI Zhen-dong; ZHONG Yan-feng; WANG Lei-ming

    2010-01-01

    @@ Hemangiopericytomas (HPCs) originating from central nervous system were increasingly reported recently.1 Intravertebral HPCs are predominantly epidural. Primary intradural HPCs of spinal cord are rare.2-5 Little subarachnoid dissemination has been reported. We reported a HPC of the cervical spinal cord with subarachnoid dissemination.

  2. The Effectiveness of Selected Dissemination Activities.

    Chapman, David W.; Johnson, Russell H.

    1981-01-01

    The dissemination activities through which college admissions officers heard about Project CHOICE, a three-year project to help colleges improve the information they provided to prospective students, were investigated. The study involved determining how well various dissemination methods (newsletter, journal articles, conference presentations,…

  3. Sexual abuse in children - what to know

    Sexual abuse - children ... boys are sexually abused before they turn 18. Sexual abuse of children is any activity that the abuser ... anus or vagina Tongue kissing Oral sex Intercourse Sexual abuse can also happen without physical contact, such as: ...

  4. Battling Sexual Abuse

    Dessoff, Alan

    2010-01-01

    From costly lawsuits on behalf of victims to negative media coverage, districts can face potentially devastating consequences as a result of sexual abuse of their students by district employees. This article offers a few tips on how to battle sexual abuse particularly in school districts. The author stresses that by adopting strong policies that…

  5. Child Sexual Abuse

    ... example, by a friend, neighbor, child care person, teacher, or stranger. When sexual abuse has occurred, a child can develop many distressing ... t tell children to 'always do everything the teacher or baby-sitter tells you to ... of guilt about the abuse, and begin the process of overcoming the trauma. ...

  6. Adolescent Substance Abuse.

    Thorne, Craig R.; DeBlassie, Richard R.

    1985-01-01

    Cummings (1979), citing evidence from the National Institute of Drug Abuse, reports that one of every eleven adult Americans suffers from a severe addictive problem. Drug addiction is epidemic among teenagers; one of every six teenagers suffers from a severe addictive problem. This paper focuses on adolescent drug/substance abuse. (Author)

  7. Special Issue: Substance Abuse.

    Fuhrmann, Barbara S., Ed.; Washington, Craig S., Ed.

    1984-01-01

    Presents ten articles about substance abuse: its effects, consequences, and strategies for intervention. Describes specific group therapy techniques and presents both a court service designed for assisting juveniles with drug/alcohol offenses, and a school-based substance abuse prevention program. Looks at strategies for counseling special…

  8. Dissemination stability and phase noise specification of fiber-cascaded RF frequency dissemination

    Gao, C; Zhu, Xi; Yuan, Y B; Wang, L J

    2015-01-01

    Over the past decade, fiber based frequency dissemination has achieved significant progresses in following aspects. To study the dissemination stability and phase noise specifications of the fiber-cascaded RF frequency dissemination system, we perform a lab-top experiment using three sets of RF modulated frequency dissemination systems. They are linked by 50 km + 50 km +45 km fiber spools. The dissemination stabilities of each segments and whole system are measured simultaneously. After that, the phase noise of each segment is also measured and the result shows that the phase noise spectrums of recovered frequency signal can be optimized via narrow band phase lock loop.

  9. Abuse Potential of Pregabalin

    Schjerning, Ole; Rosenzweig, Mary; Pottegård, Anton;

    2016-01-01

    BACKGROUND: Several case reports and epidemiological studies have raised concern about the abuse potential of pregabalin, the use of which has increased substantially over the last decade. Pregabalin is, in some cases, used for recreational purposes and it has incurred attention among drug abusers...... for causing euphoric and dissociative effects when taken in doses exceeding normal therapeutic dosages or used by alternative routes of administration, such as nasal insufflation or venous injection. The magnitude of the abuse potential and the mechanism behind it are not fully known. OBJECTIVE: The...... aim of this study was to present a systematic review of the data concerning the abuse potential of pregabalin. METHODS: We performed a systematic literature search and reviewed the preclinical, clinical and epidemiological data on the abuse potential of pregabalin. RESULTS: We included preclinical (n...

  10. Invisible Abuse: Utah's Response to Emotional Child Abuse

    Sirrine, Janae

    2010-01-01

    The very nature of emotional child abuse makes it difficult to detect and report. Nevertheless, scholars and professionals in the field of child welfare have identified emotional abuse as being equally detrimental to children as physical abuse and neglect. Many states, including Utah, have unclear definitions of emotional child abuse. The purpose of this study is to interpret how Utah has used its statute on emotional abuse in the court system and whether the current definition of emotional c...

  11. Child Abuse in India

    Mohammad Reza Iravani

    2011-02-01

    Full Text Available Child abuse is harm to, or neglect of, a child by another person, whether adult or child. Child abuse happens in all cultural, ethnic, and income groups. Child abuse can be physical, emotional - verbal, sexual or through neglect. Abuse may cause serious injury to the child and may even result in death. A problem that is only beginning to come into light in India rape, sexual abuse, and sexual harassment are worldwide issues of gender violence. There is very little research done in this area in India and only a few books have been written, keeping the subject even further from the consciousness of the country. However, the problem persists with staggering incidence, and Indians unique profile adds to the complexity of an already difficult subject. Fortunately, the issue of child sexual abuse is slowly becoming a more recognized issue, and for this reason, this paper will focus much on sexual abuse against minor children: the laws, victims, and perpetrators. Finally, an analysis of the aspects of Indian culture that make this issue particularly difficult to understand and cope with will be presented.

  12. Encountering Child Abuse at Camp.

    Durall, John K.

    1997-01-01

    Defines child abuse, including the three categories: physical, sexual, and psychological. Presents characteristics and behaviors of each type of abuse, and long-term effects. Discusses how to handle abuse that occurs at camp, and the effects on the camp. Sidebars present abuse statistics, 15 activities that promote psychological wellness, and 8…

  13. Child Abuse and Mandated Reporting

    Woika, Shirley; Bowersox, Carissa

    2013-01-01

    Teachers and teachers-in-training are mandated reporters; they are legally required to report any suspected child abuse or neglect. This article describes: (1) How to file a report; (2) How prevalent child abuse is; (3) What abuse is; (4) What it means to be a mandated reporter; (5) When the report should be made; and (6) What to do if abuse is…

  14. Educators, Schools, and Child Abuse.

    Broadhurst, Diane D.

    The booklet provides an overview on the school-related issues involved in child abuse and neglect. Definitions, causes, and effects of abuse and neglect are reviewed in the first chapter; guidelines for identifying physical and sexual abuse, neglect, and emotional maltreatment are offered in chapter 2. Aspects of reporting abuse are noted as are…

  15. Infantile abuse: Radiological diagnosis

    Ana Teresa Araujo Reyes

    2006-08-01

    Full Text Available Infantile abuse is a frequent problem, that must be suspected to bediagnosed, the children victims of infantile abuse can present anytype of injury, nevertheless there are associated injuries common toan inferred trauma that constitute radiological patterns highly specific for abuse, among them are the metafisial injuries, posterior costal fractures and first costal arc fractures, fractures of the toracolumbar region, fractures without apparent explanation, fractures in different stage of evolution, subdural hematoma, subarachnoid hemorrhage, intraparenquimatose contusion and diffuse axonal injury, which combined with the history of the trauma, the age, the development of mental abilities, as well as the mechanism guides the injury diagnose.

  16. DISSEMINATED HYDATIDOSIS: A RARE CASE REPORT

    Satish Prasad

    2014-01-01

    Hydatid disease is a worldwide zoonosis produced by the larval stage of the Echinococcus tape worm. (1) We report the CT findings of a rare case of disseminated hydatid disease which was confirmed later by exploratory laparotomy.

  17. Single Center Experience of Acute Disseminated Encephalomyelitis

    J Gordon Millichap

    2013-01-01

    Investigators at Department of Pediatrics, Neurology Division, Adana Medical Research Center; and Division of Child Neurology, Ankara, Turkey, retrospectively evaluated 15 children with acute disseminated encephalomyelitis (ADEM) in children from the center in Adana.

  18. Disseminated Intravascular Coagulation in Infectious Disease

    M. Levi; M. Schultz; T. van der Poll

    2010-01-01

    Severe infection and inflammation almost invariably lead to hemostatic abnormalities, ranging from insignificant laboratory changes to severe disseminated intravascular coagulation. Systemic inflammation as a result of severe infection leads to activation of coagulation, due to tissue factor-mediate

  19. Domestic Abuse and Child Health

    Rawlings, Samantha; Siddique, Zahra

    2014-01-01

    We examine the effects of different kinds of domestic abuse (physical violence, emotional abuse, sexual abuse and physical violence while the victim is pregnant) on health outcomes of children born to victims. We use data on approximately 0.6 million children born between 1975 and 2013 across thirty different developing countries to investigate this relationship. Comparing children of abused mothers with otherwise similar children whose mothers were not victims of abuse, we find these childre...

  20. Children, contact and domestic abuse

    Morrison, Fiona

    2014-01-01

    In recent years the issue of children’s contact with non-resident parents has been increasingly debated. The policy gaze has focused on contested contact when there are allegations of domestic abuse. Some commentators argue that in circumstances of domestic abuse, contact with an abusive father may not be in the ‘best interests’ of the child. To support these claims they point to evidence that domestic abuse adversely affects children, and domestic abuse often continues followi...

  1. Peritoneal dissemination from central neurocytoma: case report

    Coelho Neto Maurício; Ramina Ricardo; Meneses Murilo Sousa de; Arruda Walter Oleschko; Milano Jerônimo Buzetti

    2003-01-01

    OBJECTIVE: central neurocytoma is a low grade tumor of neuroglial origin and a relatively new histological entity. Only a few cases have been reported and its biological behavior is still uncertain. Some cases have shown an aggressive behavior (local recurrence, malignant dedifferentiation or CSF dissemination) and challenged the initial view of its relative benignity. A case of central neurocytoma with peritoneal dissemination is presented. CASE: a six years-old boy with recurrent neurocytom...

  2. Functional Genomics Identifies Drivers of Medulloblastoma Dissemination

    Mumert, Michael; Dubuc, Adrian; Wu, Xiaochong; Northcott, Paul A.; Chin, Steven S.; Pedone, Carolyn A; Taylor, Michael D.; Fults, Daniel W.

    2012-01-01

    Medulloblastomas are malignant brain tumors that arise in the cerebellum in children and disseminate via the cerebrospinal fluid to the leptomeningeal spaces of the brain and spinal cord. Challenged by the poor prognosis for patients with metastatic dissemination, pediatric oncologists have developed aggressive treatment protocols, combining surgery, craniospinal radiation, and high-dose chemotherapy that often cause disabling neurotoxic effects in long-term survivors. Insights into the genet...

  3. Postoperative Systemic Dissemination of Injected Elemental Mercury

    Kang, Suk-Hyung; Park, Seung Won; Moon, Kyung-Yoon

    2011-01-01

    There were only a few reports of mercury on pulmonary artery. However, there is no data on surgery related mercury dissemination. The objective of the present article is to describe one case of postoperative injected mercury dissemination. A 19-year-old man presented severe neck pain including meningeal irritation sign and abdominal pain after injection of mercury for the purpose of suicide. Radiologic study showed injected mercury in the neck involving high cervical epidural space and subcut...

  4. DISSEMINATED CYSTICERCOSIS WITH HUGE MUSCLE HYPERTROPHY

    Bandyopadhyay Debabrata; Sen Sumit

    2009-01-01

    Cysticercosis is caused by cysticercus cellulose, which is the larva of Taenia solium , the pork tapeworm. The larvae are carried in the blood stream after penetrating the walls of the alimentary tract and they lodge in different tissues like the skin, skeletal muscles, brain, fundus and heart, to cause disseminated cysticercosis. Cases of disseminated cysticercosis have rarely been reported in the literature. They may inhabit the muscles and cause muscular hypertrophy, which, at times, may ...

  5. Peritoneal dissemination from central neurocytoma: case report

    Coelho Neto Maurício

    2003-01-01

    Full Text Available OBJECTIVE: central neurocytoma is a low grade tumor of neuroglial origin and a relatively new histological entity. Only a few cases have been reported and its biological behavior is still uncertain. Some cases have shown an aggressive behavior (local recurrence, malignant dedifferentiation or CSF dissemination and challenged the initial view of its relative benignity. A case of central neurocytoma with peritoneal dissemination is presented. CASE: a six years-old boy with recurrent neurocytoma of III ventricle and left thalamus showed fast growth of tumor rest and ascites three and a half years after subtotal removal of the lesion. Tumor cells were identified in the ascitic fluid and implanted in the peritoneum. Chemotherapy was initiated immediately after diagnosis of peritoneal dissemination (etoposide, carboplatin, doxorubicin and cyclophosphamide. The patient developed metabolic imbalance and respiratory failure due to rapid formation of ascitic fluid and died 3 days after the diagnosis of peritoneal dissemination was established. CONCLUSION: central neurocytoma is a low grade tumor with low values of the proliferative index in the majority of cases. In spite of that, some tumors may present a very aggressive behavior and extraneural dissemination. Evaluation of proliferative index may be a guideline parameter for planning adjuvant therapies after surgical treatment in selected cases. Extraneural dissemination may occur in some cases specially in patients with ventriculoperitoneal shunt.

  6. Alcoholism and Alcohol Abuse

    ... drinking once you've started Physical dependence - withdrawal symptoms Tolerance - the need to drink more alcohol to feel the same effect With alcohol abuse, you are not physically dependent, but you still ...

  7. Sexual Abuse of Children.

    Csapo, Marg

    1988-01-01

    Canadian reports and legislation are reviewed to highlight the school's role in prevention and reporting of suspicions of child sexual abuse. The vulnerability of handicapped children and child pornography are two areas of victimization emphasized. (Author/DB)

  8. Drug abuse first aid

    ... medlineplus.gov/ency/article/000016.htm Drug abuse first aid To use the sharing features on this page, ... Diarrhea Hallucinations Nausea and vomiting Restlessness Shaking Death First Aid 1. Check the patient's airway, breathing, and pulse. ...

  9. Effects of Drug Abuse

    ... Treatment Drug Treatment Facts Does Drug Treatment Work? Types of Drug Treatment What Is a Relapse? Find Treatment/Rehab Resources Friends and Family Can Help Prevent Drug Abuse Help Children and Teens Stay Drug-Free Talking ...

  10. Other Drugs of Abuse

    ... Treatment Drug Treatment Facts Does Drug Treatment Work? Types of Drug Treatment What Is a Relapse? Find Treatment/Rehab Resources Friends and Family Can Help Prevent Drug Abuse Help Children and Teens Stay Drug-Free Talking ...

  11. Sexual abuse and incest

    Şahin, Figen; Taşar, Medine Ayşin

    2012-01-01

    Incest which is the severest form of child sexual abuse is defined as the sexual behaviours between close relatives whose marriage is illegal or describes inappropriate sexual behaviours within a family relation framework Incestous relation is accepted as a taboo therefore it is frequently a secret within the family and is a chronic process which is hard to recognize It is important to recognize and prevent incest because it is more difficult to be revealed compared to other forms of abuse an...

  12. Sexual abuse and incest

    Medine Ayşin Taşar; Figen Şahin

    2012-01-01

    Incest, which is the severest form of child sexual abuse is defined as the sexual behaviours between close relatives whose marriage is illegal or describes inappropriate sexual behaviours within a family relation framework. Incestous relation is accepted as a taboo, therefore it is frequently a secret within the family and is a chronic process which is hard to recognize. It is important to recognize and prevent incest because it is more difficult to be revealed compared to other forms of abus...

  13. Drug abuse in athletes

    Reardon CL; Creado S

    2014-01-01

    Claudia L Reardon, Shane Creado Department of Psychiatry, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA Abstract: Drug abuse occurs in all sports and at most levels of competition. Athletic life may lead to drug abuse for a number of reasons, including for performance enhancement, to self-treat otherwise untreated mental illness, and to deal with stressors, such as pressure to perform, injuries, physical pain, and retirement from sport. This review examines t...

  14. Detecting Medicare Abuse

    David Becker; Daniel Kessler; Mark McClellan

    2004-01-01

    This paper identifies which types of patients and hospitals have abusive Medicare billings that are responsive to law enforcement. For a 20 percent random sample of elderly Medicare beneficiaries hospitalized from 1994-98 with one or more of six illnesses that are prone to abuse, we obtain longitudinal claims data linked with Social Security death records, hospital characteristics, and state/year-level anti-fraud enforcement efforts. We show that increased enforcement leads certain types of t...

  15. Smart-tag Based Data Dissemination

    Bonnet, Philippe; Beaufour, Allan; Leopold, Martin

    2002-01-01

    Monitoring wide, hostile areas requires disseminating data between fixed, disconnected clusters of sensor nodes. It is not always possible to install long-range radios in order to cover the whole area. We propose to leverage the movement of mobile individuals, equipped with smart-tags, to dissemi......-tag based data dissemination. We use simulation to study the characteristics of the model we propose. Finally, we present an implementation based on Bluetooth smart-tags.......Monitoring wide, hostile areas requires disseminating data between fixed, disconnected clusters of sensor nodes. It is not always possible to install long-range radios in order to cover the whole area. We propose to leverage the movement of mobile individuals, equipped with smart......-tags, to disseminate data across disconnected static nodes spread across a wide area. Static nodes and mobile smart-tags exchange data when they are in the vicinity of each other; smart-tags disseminate data as they move around. In this paper, we propose an algorithm for update propagation and a model for smart...

  16. Agricultural information dissemination using ICTs: A review and analysis of information dissemination models in China

    Yun Zhang

    2016-03-01

    Full Text Available Over the last three decades, China’s agriculture sector has been transformed from the traditional to modern practice through the effective deployment of Information and Communication Technologies (ICTs. Information processing and dissemination have played a critical role in this transformation process. Many studies in relation to agriculture information services have been conducted in China, but few of them have attempted to provide a comprehensive review and analysis of different information dissemination models and their applications. This paper aims to review and identify the ICT based information dissemination models in China and to share the knowledge and experience in applying emerging ICTs in disseminating agriculture information to farmers and farm communities to improve productivity and economic, social and environmental sustainability. The paper reviews and analyzes the development stages of China’s agricultural information dissemination systems and different mechanisms for agricultural information service development and operations. Seven ICT-based information dissemination models are identified and discussed. Success cases are presented. The findings provide a useful direction for researchers and practitioners in developing future ICT based information dissemination systems. It is hoped that this paper will also help other developing countries to learn from China’s experience and best practice in their endeavor of applying emerging ICTs in agriculture information dissemination and knowledge transfer.

  17. Primary disseminated extrapulmonary multidrug resistant tuberculosis

    S K Das

    2012-01-01

    Full Text Available Disseminated tuberculosis is a common mode of presentation of tuberculosis in patients both with and without HIV/AIDS in India. However, primary multidrug resistance in disseminated tuberculosis involving only the extrapulmonary sites in an immunocompetent adult is rare. Here, we report a case of a 19-year-old man who had disseminated tuberculosis involving left pleura, pericardium, peritoneum and intraabdominal lymph nodes. He was initially taking WHO category I antituberculous drugs, but was not responding in spite of 5 months of chemotherapy. Culture of the pleural biopsy specimen grew Mycobacterium tuberculosis which was resistant to isoniazid and rifampicin. He was put on therapy for multidrug resistant tuberculosis,following 24 months of chemotherapyhe had an uneventful recovery.

  18. A rare case of disseminated cysticercosis

    Debananda Gonjhu

    2015-01-01

    Full Text Available Cysticercosis is a common tropical disease and a common cause of seizures and neurological morbidity. Neurocysticercosis (NCC is the most common manifestation of the disease involving the central nervous system (CNS. One of the uncommon manifestations of cysticercosis is its disseminated form. The most commonly affected organs are the subcutaneous tissues, skeletal muscles, lungs, brain, eyes, liver, and occasionally the heart, thyroid, and pancreas but in widespread dissemination it can involve any organ in the body. We report here a case of a 35-year-old-female with disseminated cysticercosis (DCC. She attended our hospital with headache, fever, and symptoms of multiple palpable nodules. After the investigations, she was diagnosed with DCC involving the brain and subcutaneous tissues all over the body. Then she was successfully treated with albendazole and steroids.

  19. Pineocytoma with diffuse dissemination to the leptomeninges

    Michael Selch

    2011-10-01

    Full Text Available Pineal parenchymal tumors are rare. Of the three types of pineal parenchymal tumors, pineocytomas are the least aggressive and are not known to diffusely disseminate. In this paper, we report the successful treatment of a case of pineocytoma with diffuse leptomeningeal relapse following initial stereotactic radiotherapy. A 39-year-old female presented with headaches, balance impairment, urinary incontinence, and blunted affect. A pineal mass was discovered on magnetic resonance imaging (MRI. A diagnosis of pineocytoma was established with an endoscopic pineal gland biopsy, and the patient received stereotactic radiotherapy. Ten years later, she developed diffuse leptomeningeal dissemination. The patient was then successfully treated with craniospinal radiation therapy. Leptomeningeal spread may develop as late as 10 years after initial presentation of pineocytoma. Our case demonstrates the importance of long-term follow-up of patients with pineal parenchymal tumors following radiation therapy, and the efficacy of craniospinal radiation in the treatment of leptomeningeal dissemination.

  20. How Do People with Intellectual Disabilities View Abuse and Abusers?

    Northway, Ruth; Melsome, Melissa; Flood, Samantha; Bennett, Davey; Howarth, Joyce; Thomas, Becki

    2013-01-01

    People with intellectual disabilities have a higher risk of being abused than other people, but to date research has not explored their views regarding abuse. This article reports the findings relating to one question within a participatory research study concerning the abuse of people with intellectual disabilities. This question asked what…

  1. Alienation and Domestic Abuse: How Abused Women Cope with Loneliness

    Arokach, Ami

    2006-01-01

    This study explored the manner in which abused women cope with loneliness. Eighty women, victims of domestic abuse, were compared to 84 women from the general population who have had no history of abusive relationships. A 34-item yes/no loneliness questionnaire was utilized in order to compare the "beneficial" ways of coping with loneliness in the…

  2. Substance Abuse Treatment Facilities Locator

    U.S. Department of Health & Human Services — The Substance Abuse and Mental Health Services Administration (SAMHSA) provides on-line resource for locating drug and alcohol abuse treatment programs. The...

  3. Childhood Sexual Abuse and Suicide

    ... abused and controlling for other adversities. 1 o Victims of child sexual abuse were more likely to report having a psychiatric disorder in the last 12 months, which puts victims at a higher risk of a suicide attempt ...

  4. Substance abuse in later life.

    D'Archangelo, E.

    1993-01-01

    Substance abuse affects an appreciable portion of the elderly population. Elderly people have characteristics that could hinder identification, diagnosis, intervention, and treatment of substance abuse. If physicians use strategies specific to the elderly, management is often successful.

  5. Medical Consequences of Drug Abuse

    ... Home » Related Topics » Medical Consequences Medical Consequences of Drug Abuse Email Facebook Twitter Drug addiction is a brain ... and lung disease can all be affected by drug abuse. Some of these effects occur when drugs are ...

  6. Child neglect and psychological abuse

    ... or neglect, call 911. Call the Childhelp National Child Abuse Hotline (1-800-4-A-CHILD). Know that ... can/identifying/. Accessed November 21, 2014. Read More Child abuse - physical Update Date 11/20/2014 Updated by: ...

  7. Child Abuse: The Hidden Bruises

    ... AACAP Facts for Families Guide Skip breadcrumb navigation Child Abuse - The Hidden Bruises Quick Links Facts For Families ... 5; Updated November 2014 The statistics on physical child abuse are alarming. It is estimated hundreds of thousands ...

  8. Adolescent Relationship Abuse (ARA) Toolkit

    U.S. Department of Health & Human Services — The Adolescent Relationship Abuse (ARA) Toolkit provides information and strategies on how to: incorporate abuse prevention into programming; conduct staff...

  9. Substance Abuse and Mental Health

    ... More Drugs and Alcohol Tobacco Learn More Substance Abuse and Mental Health Drugs and Alcohol Did you ... related topics from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) Free Resources for parents and ...

  10. Disseminated cysticercosis with huge muscle hypertrophy

    Bandyopadhyay Debabrata

    2009-01-01

    Full Text Available Cysticercosis is caused by cysticercus cellulose, which is the larva of Taenia solium , the pork tapeworm. The larvae are carried in the blood stream after penetrating the walls of the alimentary tract and they lodge in different tissues like the skin, skeletal muscles, brain, fundus and heart, to cause disseminated cysticercosis. Cases of disseminated cysticercosis have rarely been reported in the literature. They may inhabit the muscles and cause muscular hypertrophy, which, at times, may assume gross proportions. Morbidity is usually caused by the involvement of the central nervous system or the eyes.

  11. Working with the Abused Camper.

    Johnson, Rebecca Cowan

    1990-01-01

    Describes forms of and reasons behind child abuse. Describes camp staff's role as reporters of suspected abuse. Describes techniques for identifying and dealing with abuse victims. Recommends offering victims respect, support, advocacy, and unconditional love. Describes steps staff might take to maximize camp's effectiveness in helping abuse…

  12. Israeli Perspectives on Elder Abuse

    Rabi, Keren

    2006-01-01

    Despite the prevailing agreement among researchers that the increasing rate of elder abuse in Israel is relatively understudied, not sufficiently identified, and not appropriately addressed, literature on elderly abuse in the Israeli society remains limited. The common discourse on aging, eldercare, and elder abuse and neglect, mainly revolves…

  13. Commentary: Gender, Disability, and Abuse.

    Goldson, Edward J.

    1997-01-01

    This commentary discusses the research article "Gender Differences in Abused Children with and without Disabilities" (Sobsey and others) that follows, which found that children with disabilities are at greater risk for being maltreated, that boys are more frequently abused, and that boys with disabilities are sexually abused more frequently than…

  14. Cognitive and Emotional Differences between Abusive and Non-Abusive Fathers

    Francis, Karen J.; Wolfe, David A.

    2008-01-01

    Objective: Abusive fathers perpetrate a substantial portion of child physical abuse. Despite this, little is known about how they differ from non-abusive fathers. This study compared a broad range of cognitive and affective factors between physically abusive and non-abusive fathers. Methods: Abusive (n = 24) and non-abusive (n = 25) fathers…

  15. Differential diagnosis of disseminated periventricular calcifications

    Juvenile disseminated periventricular calcifications may occur in tuberous sclerosis, toxoplasmosis, cytomegaly, and in tuberculous meningitis. Cysticercosis, by contrast, does not result in corresponding intracerebral foci until an older age. Differential diagnosis is no problem if clinical findings are typical (tuberous sclerosis) or if serological verification is positive. However, any unclear clinical diagnosis can often be secured by CT. (orig.)

  16. Open Access Dissemination Challenges: A Case Study

    Young, Philip

    2009-01-01

    This paper explores dissemination, broadly considered, of an open access (OA) database as part of a librarian-faculty collaboration currently in progress. Metadata optimization for cataloging, repository submission, and search engines is examined, as are user notification methods. Libraries should consider their role in scholarly publishing, develop workflows to enable it, and extend their efforts to the web.

  17. Computer software management, evaluation, and dissemination

    1983-01-01

    The activities of the Computer Software Management and Information Center involving the collection, processing, and distribution of software developed under the auspices of NASA and certain other federal agencies are reported. Program checkout and evaluation, inventory control, customer services and marketing, dissemination, program maintenance, and special development tasks are discussed.

  18. Groupware: Improving Group Communication and Information Dissemination.

    Saka, Thomas; Shiigi, Clyde

    1996-01-01

    Faced with increased public expectations and decreased funding, the Hawaii Department of Education chose Lotus Notes groupware technology as an efficient means to support statewide collaboration and information dissemination among 4,200 users in 231 schools. Although initially resistant, respondents to a year-end evaluation of the project in one…

  19. Building State Capacity in Dissemination: Literature Review.

    Strang, Ernest W.

    This review was developed by and principally for the National Testing Service (NTS) Dissemination Project Staff. It is one of eight activities being used by NTS to develop a design for an evaluation of the State Capacity Building Program. The review is in two parts. The first part provides background information, evaluation methodologies and…

  20. Data Dissemination in Mobile Phone Sensor Networks

    Le, Viet-Duc; Le, Viet-Duc

    2012-01-01

    Deploying sensors over large areas is costly in terms of configuration, hardware, and maintenance. Using onboard sensors of today mobile phones can significantly reduce the expenses in monitoring areas and disseminating events or data. Via the available short-range Bluetooth and/or WiFi interfaces,

  1. Differential diagnosis of disseminated periventricular calcifications

    Rieger, P.; Piepgras, U.

    1986-08-01

    Juvenile disseminated periventricular calcifications may occur in tuberous sclerosis, toxoplasmosis, cytomegaly, and in tuberculous meningitis. Cysticercosis, by contrast, does not result in corresponding intracerebral foci until an older age. Differential diagnosis is no problem if clinical findings are typical (tuberous sclerosis) or if serological verification is positive. However, any unclear clinical diagnosis can often be secured by CT.

  2. Active Tools for Better Knowledge Dissemination.

    Mikulecky, Peter; Mikulecka, Jaroslava

    1999-01-01

    Suggests that a solution to the inadequacy and passivity problems with push and pull technologies could be in a combination of both, with an active component, adding more intelligence to the whole process of information and knowledge dissemination and supply. Describes basic principles of activity components in intelligent systems, and some…

  3. A Primer on Disseminating Applied Quantitative Research

    Bell, Bethany A.; DiStefano, Christine; Morgan, Grant B.

    2010-01-01

    Transparency and replication are essential features of scientific inquiry, yet scientific communications of applied quantitative research are often lacking in much-needed procedural information. In an effort to promote researchers dissemination of their quantitative studies in a cohesive, detailed, and informative manner, the authors delineate…

  4. Knowledge Management and Global Information Dissemination

    Umunadi, Ejiwoke Kennedy

    2014-01-01

    The paper looked at knowledge management and global information dissemination. Knowledge is a very powerful tool for survival, growth and development. It can be seen as the information, understanding and skills that you gain through education or experience. The paper was addressed under the following sub-headings: Knowledge management knowledge…

  5. New drugs of abuse.

    Rech, Megan A; Donahey, Elisabeth; Cappiello Dziedzic, Jacqueline M; Oh, Laura; Greenhalgh, Elizabeth

    2015-02-01

    Drug abuse is a common problem and growing concern in the United States, and over the past decade, novel or atypical drugs have emerged and have become increasingly popular. Recognition and treatment of new drugs of abuse pose many challenges for health care providers due to lack of quantitative reporting and routine surveillance, and the difficulty of detection in routine blood and urine analyses. Furthermore, street manufacturers are able to rapidly adapt and develop new synthetic isolates of older drugs as soon as law enforcement agencies render them illegal. In this article, we describe the clinical and adverse effects and purported pharmacology of several new classes of drugs of abuse including synthetic cannabinoids, synthetic cathinones, salvia, desomorphine, and kratom. Because many of these substances can have severe or life-threatening adverse effects, knowledge of general toxicology is key in recognizing acute intoxication and overdose; however, typical toxidromes (e.g., cholinergic, sympathomimetic, opioid, etc.) are not precipitated by many of these agents. Medical management of patients who abuse or overdose on these drugs largely consists of supportive care, although naloxone may be used as an antidote for desomorphine overdose. Symptoms of aggression and psychosis may be treated with sedation (benzodiazepines, propofol) and antipsychotics (haloperidol or atypical agents such as quetiapine or ziprasidone). Other facets of management to consider include treatment for withdrawal or addiction, nutrition support, and potential for transmission of infectious diseases. PMID:25471045

  6. Infant crying and abuse

    Reijneveld, S.A.; van der Wal, M.F.; Brugman, E.; Hira Sing, R.A.; Verloove-Vanhorick, S.P.

    2004-01-01

    Child abuse and neglect are important causes of child morbidity and death. We assessed potentially detrimental parental actions induced by infant crying in 3259 infants aged 1-6 months, in the Netherlands. In infants aged 6 months, 5.6% (95% CI 4.2-7.0) of parents reported having smothered, slapped,

  7. Drug abuse in athletes

    Reardon CL

    2014-08-01

    Full Text Available Claudia L Reardon, Shane Creado Department of Psychiatry, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA Abstract: Drug abuse occurs in all sports and at most levels of competition. Athletic life may lead to drug abuse for a number of reasons, including for performance enhancement, to self-treat otherwise untreated mental illness, and to deal with stressors, such as pressure to perform, injuries, physical pain, and retirement from sport. This review examines the history of doping in athletes, the effects of different classes of substances used for doping, side effects of doping, the role of anti-doping organizations, and treatment of affected athletes. Doping goes back to ancient times, prior to the development of organized sports. Performance-enhancing drugs have continued to evolve, with “advances” in doping strategies driven by improved drug testing detection methods and advances in scientific research that can lead to the discovery and use of substances that may later be banned. Many sports organizations have come to ban the use of performance-enhancing drugs and have very strict consequences for people caught using them. There is variable evidence for the performance-enhancing effects and side effects of the various substances that are used for doping. Drug abuse in athletes should be addressed with preventive measures, education, motivational interviewing, and, when indicated, pharmacologic interventions. Keywords: doping, athletes, steroids, drug abuse, mental illness

  8. Child sexual abuse

    Background: Child sexual abuse with significant impact on victim's physical, mental and social health has now been recognized as existing on an appreciable scale worldwide. Diversity of opinions exist about the concept, types, prevalence and repercussions along with a paucity of systematic and scientific work in the developing world including Pakistan. Objective: This paper aims at reviewing the literature for clarification of concept, update of estimates and correlates, and to identify lines for future research. Data sources: The literature was search through BMJ-Medline for international data, supplemented by local data through CPSP-MEDLIP service. The search term child sexual abuse with associated sub-heads were used. No constraint of time period, publication type or source applied except english Language version Comparative findings: Wide variations identified in conceptual boundaries with consequent impact on prevalence estimates. Agreement found for its existence as an international problem with rates ranging from 7% - 36% for women and 3% - 29% for men. Female abused 1.5-3 times more than male with exponential high rates in age group 3-6 years and 8-11 years. In 2/3 cases the perpetrator identified belonged to nuclear or extended family. Significant association exists with early onset of psychiatric ailments like substance abuse, eating disorders, personality disorders, dissociative disorders and depression. Conclusion and Suggestion: The need for extensive research studies in immense in developing countries like Pakistan where environmental circumstances suggest its presence at rates higher than the identified elsewhere. In addition to facilitate awareness and perhaps to clarify the concept as well as the prevalence of child sexual abuse researchers need to select methodologies and instruments with international comparison in mind. (author)

  9. Wife abuse in rural Bangladesh.

    Dalal, Koustuv; Rahman, Fazlur; Jansson, Bjarne

    2009-09-01

    Intimate partner violence (IPV) is a global public health and gender problem, especially in low-income countries. The study focused on verbal abuse, physical abuse and abuse by restricting food provision to wives by their husbands by victim and perpetrator characteristics, emphasizing the socioeconomic context of rural Bangladesh. Using a cross-sectional household survey of 4411 randomly selected married women of reproductive age, the study found that a majority of the respondents are exposed to verbal abuse (79%), while 41% are exposed to physical abuse. A small proportion (5%) of the women had suffered food-related abuse. Risk factors observed were age of the wife, illiteracy (of both victims and perpetrators), alcohol misuse, dowry management, husband's monetary greed involving parents-in-law, and wife's suspicions concerning husband's extramarital affairs. Well-established risk factors for wife abuse, along with dowry and husband's monetary greed, have a relatively high prevalence in rural Bangladesh. PMID:19534836

  10. Dissemination Matters: Influences of Dissemination Activities on User Types in an Online Educational Community

    Min Yuan

    2014-09-01

    Full Text Available Emerging online educational communities provide spaces for teachers to find resources, create instructional activities, and share these activities with others. Within these online communities, individual users’ activities may vary widely, and thus different user types can be identified. In addition, users’ patterns of activities in online communities are dynamic, and further can be affected by dissemination activities. Through analyzing usage analytics in an online teacher community called the Instructional Architect, this study explores the influences of dissemination activities on the usage patterns of different user types. Results show that dissemination activities can play an important role in encouraging users’ active participation, while the absence of dissemination activities can further increase participation inequality.

  11. Information, Vol. 1, Number 4. Teacher Corps Dissemination Project Bulletin.

    Rosenau, Fred S., Ed.

    Guidelines are provided for disseminating information on teacher corps projects. Information is given on experienced disseminators such as existing networks that are available to help in planning. Suggestions are made on targeting information and marketing. (JD)

  12. Dissemination of CERN Technologies Through External Entrepreneurs

    Lande, Bjørnulf Visdal; Huuse, Henning

    2008-01-01

    This study focuses on dissemination of innovations through external entrepreneurs. The innovations studied are developed at the European Organization for Nuclear Research (CERN) and commercialized by entrepreneurs establishing spin-off companies on the outside of the Organization. The objective of this study is to provide knowledge to facilitate future external entrepreneurs to increase dissemination of CERN technologies. The research questions looks at the timeline from preparations for creating the spin-off company, until having a product for commercialization in the market. A qualitative cross case investigation was conducted to assess the experiences of four spin-off companies. A framework was created to structure the discussion by finding and categorizing impeding- and success factors seen from the entrepreneurs point of view. The findings where structured in three phases respectively, the time before starting the company, the beginning of the company and the final development before selling products. Th...

  13. Disseminated tuberculosis in an AIDS/HIV-infected patient.

    Zahra Abdi-Liae; Pardis Moradnejad; Neda Alijani; Hamide Khazraiyan; Sedigeh Mansoori; Naseh Mohammadi

    2013-01-01

    Disseminated tuberculosis (TB) is commonly seen in HIV-infected patients and is major cause of death in these patients. In HIV-infected patients disseminated tuberculosis is frequently undiagnosed or misdiagnosed. In this article we report a case of disseminated TB in a HIV-infected patient with a relatively long history of fever and other complaints without definite diagnosis. Diagnosis of disseminated TB was confirmed by bone marrow biopsy and polymerase chain reaction analysis (PCR) of the...

  14. Tension Hydrothorax Related to Disseminated Endometriosis

    AnnaKate Deal, MD

    2016-01-01

    Full Text Available We present the case of a 34-year-old woman presenting to the emergency department (ED with dyspnea, cough, and fever. She was found to have a tension hydrothorax and was treated with ultrasound-guided thoracentesis in the ED. Subsequent inpatient evaluation showed the patient had disseminated endometriosis. Tension hydrothorax has not been previously described in the literature as a complication of this disease.

  15. Disseminated cysticercosis with pulmonary and cardiac involvement

    Jain Bharat; Sankhe Shilpa; Agrawal Mukta; Naphade Prashant

    2010-01-01

    Pulmonary and cardiac involvement by cysticercosis is extremely rare, and is usually asymptomatic. We report the case of a 19-year-old boy who presented with a history of headache and vomiting and was found to have disseminated cysticercosis with pulmonary and cardiac involvement; the emphasis is on the rare occurrence of pulmonary, cardiac, pancreatic, intraocular, and extradural spinal canal involvement in the same patient. This case demonstrates the extent to which cysticercosis can be dis...

  16. Abuse Tolerance Improvements

    Orendorff, Christopher J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Nagasubramanian, Ganesan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Fenton, Kyle R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Allcorn, Eric [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-10-01

    As lithium-ion battery technologies mature, the size and energy of these systems continues to increase (> 50 kWh for EVs); making safety and reliability of these high energy systems increasingly important. While most material advances for lithium-ion chemistries are directed toward improving cell performance (capacity, energy, cycle life, etc.), there are a variety of materials advancements that can be made to improve lithium-ion battery safety. Issues including energetic thermal runaway, electrolyte decomposition and flammability, anode SEI stability, and cell-level abuse tolerance continue to be critical safety concerns. This report highlights work with our collaborators to develop advanced materials to improve lithium-ion battery safety and abuse tolerance and to perform cell-level characterization of new materials.

  17. Types of abuse and risk factors associated with elder abuse

    Lacher, Simone; Wettstein, Albert; Senn, Oliver; Rosemann, Thomas; Hasler, Susann

    2016-01-01

    PRINCIPLES Detecting elder abuse is challenging because it is a taboo, and many cases remain unreported. This study aimed to identify types of elder abuse and to investigate its associated risk factors. METHODS Retrospective analyses of 903 dossiers created at an Independent Complaints Authority for Old Age in the Canton of Zurich, Switzerland, from January 1, 2008 to October 31, 2012. Characteristics of victims and perpetrators, types of abuse, and associated risk factors related to...

  18. Computational scalability of large size image dissemination

    Kooper, Rob; Bajcsy, Peter

    2011-01-01

    We have investigated the computational scalability of image pyramid building needed for dissemination of very large image data. The sources of large images include high resolution microscopes and telescopes, remote sensing and airborne imaging, and high resolution scanners. The term 'large' is understood from a user perspective which means either larger than a display size or larger than a memory/disk to hold the image data. The application drivers for our work are digitization projects such as the Lincoln Papers project (each image scan is about 100-150MB or about 5000x8000 pixels with the total number to be around 200,000) and the UIUC library scanning project for historical maps from 17th and 18th century (smaller number but larger images). The goal of our work is understand computational scalability of the web-based dissemination using image pyramids for these large image scans, as well as the preservation aspects of the data. We report our computational benchmarks for (a) building image pyramids to be disseminated using the Microsoft Seadragon library, (b) a computation execution approach using hyper-threading to generate image pyramids and to utilize the underlying hardware, and (c) an image pyramid preservation approach using various hard drive configurations of Redundant Array of Independent Disks (RAID) drives for input/output operations. The benchmarks are obtained with a map (334.61 MB, JPEG format, 17591x15014 pixels). The discussion combines the speed and preservation objectives.

  19. Disseminated cutaneous histoplasmosis in an immunocompetent adult

    Manoj Harnalikar

    2012-01-01

    Full Text Available Histoplasmosis, a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum var capsulatum and Histoplasma capsulatum var duboisii is endemic to many parts of the world. The clinical manifestations range from acute or chronic pulmonary infection to a progressive disseminated disease. After initial exposure to the fungus, the infection is self-limited and restricted to the lungs in 99% of healthy individuals. The remaining 1%, however, progress to either disseminated or chronic disease involving the lungs, liver, spleen, lymph nodes, bone marrow or rarely, the skin and mucous membranes. Mucocutaneous histoplasmosis is frequently reported in patients with acquired immune deficiency syndrome (AIDS, but it is rare in immunocompetent hosts. A 60-year-old male presented with asymptomatic swelling of the hard palate and crusted papules and nodules over the extremities, face and trunk. Clinically, the diagnoses of cutaneous cryptococcosis versus histoplasmosis was considered in this patient. A chest X-ray revealed hilar lymphadenopathy. Enzyme-linked immunosorbent assay (ELISA for human immunodeficiency virus (HIV was nonreactive. Skin biopsy revealed multiple tiny intracellular round yeast forms with a halo in the mid-dermis. Culture of the skin biopsy in Sabouraud′s dextrose agar showed colonies of Histoplasma capsulatum. Despite an investigation including no evidence of underlying immunosuppression was found, he was started on IV amphotericin-B (0.5 mg/kg/day. However, the patient succumbed to his disease 2 days after presentation. We report a rare case of disseminated cutaneous histoplasmosis in an immunocompetent individual.

  20. Computed tomographic evaluation in the peritoneal dissemination of gastric cancer

    We assessed the peritoneal dissemination of gastric cancer by CT in patients with neither ascites nor mesenteric thickening. A gastric wall over 20 mm in thickness and CT pattern of laminary type and bulk type were observed in patients with peritoneal dissemination. Dilatation of omental branches may suggest peritoneal dissemination of gastric cancer. (author)

  1. Medical Diagnosis of the Sexually Abused Child.

    Bays, Jan; Chadwick, David

    1993-01-01

    This article on medical diagnosis of the sexually abused child summarizes clinical research on physical findings in nonabused children, abused children, and abused children with independent confirmation of abuse. A classification of physical findings is proposed along a continuum of certainty that sexual abuse has occurred. (Author/JDD)

  2. Dental treatment abuse.

    Chalakkal, Paul; Ataide, Ida De Noronha De; Krishnan, Ramesh; Pavaskar, Rajdeep

    2014-07-01

    These case reports highlight dental treatment abuse performed by a quack on children. The anterior teeth of these children were metal capped using cement, which were otherwise healthy. The treatment was done on children without parental consent by a quack from Denmark who gave the reason as for resolving proclination of upper permanent incisors. The unanatomic, unaesthetic metal caps were removed after the child reported to the Department of Pedodontics and Preventive Dentistry. PMID:25177645

  3. Opportunities for computer abuse

    Willison, Robert; Backhouse, James

    2005-01-01

    Systems risk refers to the likelihood that an IS is inadequately guarded against certain types of damage or loss. While risks are posed by acts of God, hackers and viruses, consideration should also be given to the ‘insider’ threat of dishonest employees, intent on undertaking some form of computer abuse. Against this backdrop, a number of researchers have addressed the extent to which security managers are cognizant of the very nature of systems risk. In particular, they note how security pr...

  4. Dental Treatment Abuse

    Chalakkal, Paul; Ataide, Ida De Noronha De; Krishnan, Ramesh; Pavaskar, Rajdeep

    2014-01-01

    These case reports highlight dental treatment abuse performed by a quack on children. The anterior teeth of these children were metal capped using cement, which were otherwise healthy. The treatment was done on children without parental consent by a quack from Denmark who gave the reason as for resolving proclination of upper permanent incisors. The unanatomic, unaesthetic metal caps were removed after the child reported to the Department of Pedodontics and Preventive Dentistry.

  5. Drug abuse in athletes.

    Reardon, Claudia L; Creado, Shane

    2014-01-01

    Drug abuse occurs in all sports and at most levels of competition. Athletic life may lead to drug abuse for a number of reasons, including for performance enhancement, to self-treat otherwise untreated mental illness, and to deal with stressors, such as pressure to perform, injuries, physical pain, and retirement from sport. This review examines the history of doping in athletes, the effects of different classes of substances used for doping, side effects of doping, the role of anti-doping organizations, and treatment of affected athletes. Doping goes back to ancient times, prior to the development of organized sports. Performance-enhancing drugs have continued to evolve, with "advances" in doping strategies driven by improved drug testing detection methods and advances in scientific research that can lead to the discovery and use of substances that may later be banned. Many sports organizations have come to ban the use of performance-enhancing drugs and have very strict consequences for people caught using them. There is variable evidence for the performance-enhancing effects and side effects of the various substances that are used for doping. Drug abuse in athletes should be addressed with preventive measures, education, motivational interviewing, and, when indicated, pharmacologic interventions. PMID:25187752

  6. Breaking the cycle of abuse.

    Egeland, B; Jacobvitz, D; Sroufe, L A

    1988-08-01

    The aim of this study was to identify variables that distinguish mothers who broke the cycle of abuse from mothers who were abused as children and who also abused their own children. Based on maternal interviews and questionnaires completed over a 64-month period, measures of mothers' past and current relationship experiences, stressful life events, and personality characteristics were obtained. Abused mothers who were able to break the abusive cycle were significantly more likely to have received emotional support from a nonabusive adult during childhood, participated in therapy during any period of their lives, and to have had a nonabusive and more stable, emotionally supportive, and satisfying relationship with a mate. Abused mothers who reenacted their maltreatment with their own children experienced significantly more life stress and were more anxious, dependent, immature, and depressed. PMID:3168615

  7. ABUSE OF ANABOLIC ANDROGENIC STEROIDS

    Abbas Yavari

    2009-01-01

    According to the International Olympic Committee, the abuse of anabolic androgenic steroids (AASS) is found in over 50% of positive doping tests. AASS abuse is not restricted to the organized sports and widespread use. It remains as an unsolved public-health problem. Lower black market price, easier access to AASS, bodybuilding clubs and internet advertising are factors of this increasingly misuse. There is not real data about the prevalence of AASS abuse in various populations or countries, ...

  8. ART TEACHERS AND ABUSED CHILDREN

    Vesela Bilić, Vesna

    2011-01-01

    The aim of this paper is to provide a basic overview of how art teachers can use art drawings (artistic expression) to identify and assist children who are traumatized by abuse. Children's exposure to different forms of child abuse in families (physical, emotional and sexual abuse and neglect), and exposure to traditional (bullying) or electronic (cyberbullying) peer violence may result in  serious consequences for the child's health, welfare and functioning in life and school. Since th...

  9. Therapeutic approach to sexual abuse.

    Furniss, T; Bingley-Miller, L; Bentovim, A

    1984-01-01

    An account is given of the development of a treatment project for sexually abused children and their families. We review incidence data which indicate that sexual abuse of children is likely to be a far more frequent problem than has been recognised and cause an appreciable degree of psychological damage. Professional responses to this are confused and treatment facilities limited. Sexual abuse is seen as an expression of severe relationship problems in the family and therapeutic provision is...

  10. Child abuse in panic disorder

    Bonevski Dimitar; Novotni Antoni

    2008-01-01

    Introduction Numerous authors associate child abuse with serious long-term consequences to the general and psychological well-being in particular. Clinical research to date reveals strong correlation between childhood abuse and neglect and anxiety disorders, especially panic disorder. Material and Methods This study was conducted in order to assess the level of emotional, physical and sexual childhood abuse as well as the physical and emotional childhood neglect in 40 adult patients suffering...

  11. Nurses' perceptions about child abuse

    Ahmad Saifan; Intima A Alrimawi; Ibrahim Bashaireh

    2015-01-01

    Background: Despite the efforts to protect children around the world, child abuse and neglect remain serious and global problems. In Palestine, child abuse is hidden under the community culture, does not appear in the Ministry of Health official reports, and little is known about nurses’ perceptions towards this phenomenon.Objectives: To identify nurses’ perceptions about child abuse definition, whether they faced such cases during their work, and how they managed them.Methods: Data were coll...

  12. Early Detection of Child Abuse

    Shearman, J. K.

    1987-01-01

    Child abuse, neglect and deprivation are more common than was previously thought. Family physicians are in a unique position to help abusers and abused because of their knowledge of patients from the cradle to the grave. They should use this knowledge to observe clues about parenting potential and should make a thorough family history a routine part of history taking in potential parents. They should also observe patients carefully during pregnancy and early childhood to detect parenting prob...

  13. Forensic aspects of animal abusing

    Aleksić Jelena; Jović Slavoljub

    2008-01-01

    Animal abuse is important social issue, which includes a wide range of behaviors of humans that are harmful to animals, starting from unintentional neglect to intentional cruelty. Types of animal abuse are different and they can include physical, sexual, emotional abuse or neglect. Training dogs for fights and dog fighting are considered to be neglection of animals. Forensic veterinarians are called for testifining more often now for presenting the evidence that can lead to making a case rega...

  14. Diagnostic imaging of child abuse

    Oguma, Eiji; Aihara, Toshinori [Saitama Children' s Medical Center, Iwatsuki (Japan)

    2002-04-01

    The major role of imaging in cases of suspected child abuse is to identify the physical injuries and to confirm the occurrence of abuse. In severely abused infants, the imaging findings may be the only evidence for a diagnosis of inflicted injury. Imaging may be the first clue to abuse in children seen with apparent other conditions and lead to appropriate measures to protect them from the risk of more serious injury. The radiologist must be familiar with imaging findings of inflicted injuries to fulfill these roles. (author)

  15. Diagnostic imaging of child abuse

    The major role of imaging in cases of suspected child abuse is to identify the physical injuries and to confirm the occurrence of abuse. In severely abused infants, the imaging findings may be the only evidence for a diagnosis of inflicted injury. Imaging may be the first clue to abuse in children seen with apparent other conditions and lead to appropriate measures to protect them from the risk of more serious injury. The radiologist must be familiar with imaging findings of inflicted injuries to fulfill these roles. (author)

  16. Diagnostic imaging of child abuse

    This book provides a description for all the known radiological alterations occurring in child abuse. This allows for precise interpretation of findings by radiologists. It also helps eliminate the confusion among both clinicians and non-medical personnel involved in the diagnosis, management, and legal issues related to child abuse. CONTENTS: Introduction; Skeletal trauma: general considerations; Extremity trauma; Bony thoracic trauma; Spinal trauma; Dating fractures; Visceral trauma; Head trauma; Miscellaneous forms of abuse and neglect; The postmortem examination; Differential diagnosis of child abuse; Legal considerations; Psychosocial considerations; Technical considerations and dosimetry

  17. Abusive Head Trauma (Shaken Baby Syndrome)

    ... Things to Know About Zika & Pregnancy Abusive Head Trauma (Shaken Baby Syndrome) KidsHealth > For Parents > Abusive Head ... babies tend to cry the most. How These Injuries Happen Abusive head trauma results from injuries caused ...

  18. Men's Health: Alcohol and Drug Abuse

    ... This information in Spanish ( en español ) Alcohol and drug abuse More information on alcohol and drug abuse Alcohol ... Return to top More information on Alcohol and drug abuse Explore other publications and websites Consequences of the ...

  19. Alcohol Abuse and Other Psychiatric Disorders

    ... Health Disparities Other Psychiatric Disorders Other Substance Abuse HIV/AIDS Other Psychiatric Disorders In the current Diagnostic and Statistical Manual of Mental Disorders (DSM), alcohol abuse and other substance abuse ...

  20. A framework for disseminating evidence-based health promotion practices.

    Harris, Jeffrey R; Cheadle, Allen; Hannon, Peggy A; Forehand, Mark; Lichiello, Patricia; Mahoney, Eustacia; Snyder, Susan; Yarrow, Judith

    2012-01-01

    Wider adoption of evidence-based, health promotion practices depends on developing and testing effective dissemination approaches. To assist in developing these approaches, we created a practical framework drawn from the literature on dissemination and our experiences disseminating evidence-based practices. The main elements of our framework are 1) a close partnership between researchers and a disseminating organization that takes ownership of the dissemination process and 2) use of social marketing principles to work closely with potential user organizations. We present 2 examples illustrating the framework: EnhanceFitness, for physical activity among older adults, and American Cancer Society Workplace Solutions, for chronic disease prevention among workers. We also discuss 7 practical roles that researchers play in dissemination and related research: sorting through the evidence, conducting formative research, assessing readiness of user organizations, balancing fidelity and reinvention, monitoring and evaluating, influencing the outer context, and testing dissemination approaches. PMID:22172189

  1. Early childhood sexual abuse increases suicidal intent

    Lopez-Castroman, Jorge; Melhem, Nadine; Birmaher, Boris; Greenhill, Laurence; Kolko, David; Stanley, Barbara; Zelazny, Jamie; Brodsky, Beth; Garcia-Nieto, Rebeca; Burke, Ainsley K.; Mann, J. John; Brent, David A.; Oquendo, Maria A.

    2013-01-01

    Childhood sexual abuse has been consistently associated with suicidal behavior. We studied suicide attempt features in depressed individuals sexually abused as children. On average, sexual abuse started before age 9. It frequently coexisted with physical abuse. Suicide attempters more often had personality disorders and had endured abuse for longer, but did not differ in terms of other clinical characteristics from non-attempters. Earlier onset of sexual abuse and its duration were associated...

  2. Epidemiology Abuse: Epidemiological and Psychosocial Models of Drug Abuse

    Jacobs, Phillip E.

    1976-01-01

    In a paper presented at the National Drug Abuse Conference April 4-7, 1975, New Orleans, Louisiana, epidemiological and psychosocial approaches to drug abuse are discussed. An approach reflecting an appreciation of the psychological/social/political realities involved in addiction as well as a grounding in epidemiological principles and data is…

  3. Next generation sequencing of disseminated tumor cells

    ElenKristineMøller

    2013-12-01

    Full Text Available Disseminated tumor cells (DTCs detected in the bone marrow have been shown as an independent prognostic factor for women with breast cancer. However, the mechanisms behind the tumor cell dissemination are still unclear and more detailed knowledge is needed to fully understand why some cells remain dormant and others metastasize. Sequencing of single cells has opened for the possibility to dissect the genetic content of subclones of a primary tumor, as well as DTCs. Previous studies of genetic changes in DTCs have employed single-cell array comparative genomic hybridization which provides information about larger aberrations. To date, next generation sequencing provides the possibility to discover new, smaller and copy neutral genetic changes. In this study, we performed whole genome amplification and subsequently next generation sequencing to analyze DTCs from two breast cancer patients. We compared copy number profiles of the DTCs and the corresponding primary tumor generated from sequencing and SNP-CGH data, respectively. While one tumor revealed mostly whole arm gains and losses, the other had more complex alterations, as well as subclonal amplification and deletions. Whole arm gains or losses in the primary tumor were in general also observed in the corresponding DTC. Both primary tumors showed amplification of chromosome 1q and deletion of parts of chromosome 16q, which was recaptured in the corresponding DTCs. Interestingly, clear differences were also observed, indicating that the DTC underwent further evolution at the copy number level. This study provides a proof-of-principle for sequencing of DTCs and correlation with primary copy number profiles. The analyses allow insight into tumor cell dissemination and show ongoing copy number evolution in DTCs compared to the primary tumors.

  4. Disseminated toxocariasis in an immunocompetent host

    Madan; Raj; Aryal; Paras; Karmacharya; Amrit; Pokharel; Smith; Giri; Ranjan; Pathak; Richard; Alweis

    2014-01-01

    Toxocariasis is a zoonotic infection caused by Toxocara canis,or less commonly,Toxocara cati,which is one of the most common zoonotic infections worldwide.It commonly affects the pediatric and immunocompromised population;however,it has rarely been reported in the immunocompetent adults.Two of the well-recognized syndromes in children are visceral larva migrans and ocular larva migrans.Infection in adults usually ranges from asymptomatic to nonspecific symptoms which makes the diagnosis challenging.A case of 36 year-old male was presented with disseminated toxocariasis with pulmonary and hepatic involvement and striking peripheral eosinophilia.

  5. Disseminated toxocariasis in an immunocompetent host

    Madan Raj Aryal

    2014-10-01

    Full Text Available Toxocariasis is a zoonotic infection caused by Toxocara canis, or less commonly, Toxocara cati, which is one of the most common zoonotic infections worldwide. It commonly affects the pediatric and immunocompromised population; however, it has rarely been reported in the immunocompetent adults. Two of the well-recognized syndromes in children are visceral larva migrans and ocular larva migrans. Infection in adults usually ranges from asymptomatic to non-specific symptoms which makes the diagnosis challenging. A case of 36 year-old male was presented with disseminated toxocariasis with pulmonary and hepatic involvement and striking peripheral eosinophilia.

  6. Disseminated toxocariasis in an immunocompetent host

    Madan Raj Aryal; Paras Karmacharya; Amrit Pokharel; Smith Giri; Ranjan Pathak; Richard Alweis

    2014-01-01

    Toxocariasis is a zoonotic infection caused by Toxocara canis, or less commonly, Toxocara cati, which is one of the most common zoonotic infections worldwide. It commonly affects the pediatric and immunocompromised population; however, it has rarely been reported in the immunocompetent adults. Two of the well-recognized syndromes in children are visceral larva migrans and ocular larva migrans. Infection in adults usually ranges from asymptomatic to non-specific symptoms which makes the diagnosis challenging. A case of 36 year-old male was presented with disseminated toxocariasis with pulmonary and hepatic involvement and striking peripheral eosinophilia.

  7. Opportunities for computer abuse

    Willison, Robert Andrew; Backhouse, James

    2005-01-01

    Systems risk refers to the likelihood that an IS is inadequately guarded against certain types of damage or loss. While risks are posed by acts of God, hackers and viruses, consideration should also be given to the `insider' threat of dishonest employees, intent on undertaking some form of computer...... for the offender. To achieve this goal a model known as the `Crime Specific Opportunity Structure' is advanced. Focussing on the opportunities for computer abuse, the model addresses the nature of such opportunities with regards to the organisational context and the threats posed by rogue employees. Drawing...

  8. Abusing National Privilege

    2011-01-01

    As U.S. mortgage finance giants-Fannie Mae and Freddie Mac-try to sell their huge backlog of foreclosed homes, they face foreclosures themselves as the U.S. Government contemplates cutting their government-backed support as indicated by a white paper issued by the Obama administration in February. Zhang Monan, an associate research fellow with the State Information Center, said the downfall of Fannie Mae and Freddie Mac is the result of abuses of privileges the two companies have enjoyed since their inception.

  9. Marijuana abuse and bullous emphysema

    Harsh Golwala

    2012-01-01

    Marijuana abuse has been on an increasing trend worldwide in the last decade. We hereby report a case of severe bullous emphysema resulting in pneumothorax in a patient with few years of marijuana abuse. We also review the major conditions in the differential diagnosis of bullous emphysema in adults.

  10. Caregiver Stress and Elder Abuse

    ... how to report it: The National Center on Elder Abuse 1225 I Street, N.W., Suite 725 Phone: (202) 898-2586 Washington, D.C. 20005 Email: NCEA@nasua.org http://www.elderabusecenter.org National Committee for the Prevention of Elder Abuse 1101 Vermont Ave. NW, Suite 1000 Phone: ( ...

  11. Personality Development Following Sexual Abuse.

    Tong, Liz; And Others

    1987-01-01

    The follow-up study evaluated 37 girls and 12 boys (aged 5-19 years) who had been sexually abused an average of 2.6 years previously. Results found that, compared to control children, abused children had less confidence, fewer friends, more aggression, increased sexual awareness, and more behavior and academic problems. (Author/JDD)

  12. Drug Abuse and the Schools

    Greenberg, Jerrold S.

    1971-01-01

    In reviewing some of the background information regarding the extent of drug abuse and the types of measures presently being used, this article describes in more detail the role of the school in drug abuse. Emphasis is placed on drug education from the viewpoint of youth. (Author)

  13. The abuse of nuclear power

    Different aspects of possible abuse of nuclear power by countries or individuals are discussed. Special attention is paid to the advantage of nuclear power, despite the risk of weapon proliferation or terrorism. The concepts of some nuclear power critics, concerning health risks in the nuclear sector are rejected as untrue and abusive

  14. ABUSE OF ANABOLIC ANDROGENIC STEROIDS

    Abbas Yavari

    2009-09-01

    Full Text Available According to the International Olympic Committee, the abuse of anabolic androgenic steroids (AASS is found in over 50% of positive doping tests. AASS abuse is not restricted to the organized sports andwidespread use. It remains as an unsolved public-health problem.Lower black market price, easier access to AASS, bodybuilding clubs and internet advertising are factors of this increasingly misuse. There is not real data about the prevalence of AASS abuse in various populations or countries, because most of athletes or students, due to their prohibition or ethical aspects do not admit to AASS abuse. Often they are aware of the risks of their choice and yet, are eager to put themselves at risk without deeper consideration. The abusers use them to improve their physical fitness and appearance.Present article has been collected to elucidate the risks and adverse effects of AASS and explanation of mechanisms of these events.

  15. Radioactivity measurements as tool for physics dissemination

    In general people associate environmental radioactivity with the artificial radioactivity and knows very little about natural radioactivity. Thus there is a critical need to improve nuclear physics public education. From 2005 in Italy two programs were promoted from Ministry of Education and University and National Institute of Nuclear Physics (INFN) for scientific dissemination in the field of environmental radioactivity. High school students in many Italian regions were involved in particular in indoor radon measurements. With this program students acquired awareness about the risks of inhalation of radon and its progeny and at the same time contributed to carry out radon monitoring, participating to all the experimental phases, from detectors set-up to data analysis. In particular we report about the activities carried out at Catania University and INFN division regarding a survey in the eastern Sicily. The overall monitoring, spanned over a period of 5 years, was carried out using passive nuclear track detection technique, through CR-39 dosimeters. In total about 500 detectors were placed in dwellings and schools in 57 locations. The investigated area have shown medium-high indoor radon concentrations, higher than the Italian average (70 Bq/m3). From the evaluation of the participating teachers and students, this kind of activities represents a successful strategy to enhance dissemination of physics, in particular in radioactivity topics. (author)

  16. Disseminated intravascular coagulation in solid tumors

    It is estimated that 20-25% of cases of disseminated intravascular coagulation (DIC) relate to an underlying neoplasia primarily hematologic. It is estimated that about 5% of patients with solid tumors have CID clinic, although the incidence of subclinical alterations is much higher. The CID is not limited to the activation of the coagulation cascade, which leads to bleeding micro thrombosis and consumption of coagulation factors. Solid tumors are frequently associated adenocarcinomas producers mucin (especially gastric), usually in the context of a disseminated disease. The mucin may act as a promoter of the cascade, but probably it is a multi-event. High levels of TNF to produced by the tumor mass and chemotherapy-induced cell lysis have Also linked. Although the bleeding is usually oriented diagnosis, the most frequent cause of death is thrombosis. There are no specific tests for diagnosis. Elevated levels of D-dimer and products oriented fibrinogen degradation diagnosis. No reduction fibrinogen and almost always, one thrombocytopenia consumption. Treatment is complex and there is no consensus on many points. To recover the lost factors for consumption, it is recommended to use fresh frozen plasma and / or washed red blood cells. the heparin anticoagulation low dose is indicated since the disease causal can not be controlled quickly, but should not be initiated if there thrombocytopenia 50.000.El under profuse bleeding can require the use of tranexamic acid or EACA. Acute DIC, the case of our patient, is rare and very serious

  17. Clean coal technology promotion and dissemination

    Minchener, A.J.; McMullan, J.T.; Kubica, K. (and others) [IEA Coal Research Ltd, London (United Kingdom)

    2008-07-01

    This project has provided a means to valorise the technical achievements of the CCT power generation RD&D activities arising from the ECSC and RFCS coal utilisation programmes. The focus has been on promotion and dissemination of such results to major coal-using Member States that have recently joined the European Union, namely Poland, the Czech Republic and Romania. A comprehensive review of the scope and achievements of the ECSC and RFCS projects on coal-fired power generation RD&D has been prepared and posted on the IEACCC website. This document has been translated by the partners in the three designated States and disseminated to their respective national stakeholders. Workshops have been held successfully in each country to promote the findings of the review and to determine their respective primary interests in future RD&D. The attendees have included representatives of major power plant operators, equipment manufacturers and developers, research institutes and universities. Very positive feedback was received from those stakeholders. The project has been completed with the circulation of the report and associated information to comparable stakeholders in the EU-15 countries and other newer members of the European Union via various networks and associations. 2 tabs., 3 apps.

  18. Hydrogen Technical Analysis -- Dissemination of Information

    George Kervitsky, Jr.

    2006-03-20

    SENTECH is a small energy and environmental consulting firm providing technical, analytical, and communications solutions to technology management issues. The activities proposed by SENTECH focused on gathering and developing communications materials and information, and various dissemination activities to present the benefits of hydrogen energy to a broad audience while at the same time establishing permanent communications channels to enable continued two-way dialog with these audiences in future years. Effective communications and information dissemination is critical to the acceptance of new technology. Hydrogen technologies face the additional challenge of safety preconceptions formed primarily as a result of the crash of the Hindenburg. Effective communications play a key role in all aspects of human interaction, and will help to overcome the perceptual barriers, whether of safety, economics, or benefits. As originally proposed SENTECH identified three distinct information dissemination activities to address three distinct but important audiences; these formed the basis for the task structure used in phases 1 and 2. The tasks were: (1) Print information--Brochures that target the certain segment of the population and will be distributed via relevant technical conferences and traditional distribution channels. (2) Face-to-face meetings--With industries identified to have a stake in hydrogen energy. The three industry audiences are architect/engineering firms, renewable energy firms, and energy companies that have not made a commitment to hydrogen (3) Educational Forums--The final audience is students--the future engineers, technicians, and energy consumers. SENTECH will expand on its previous educational work in this area. The communications activities proposed by SENTECH and completed as a result of this cooperative agreement was designed to compliment the research and development work funded by the DOE by presenting the technical achievements and validations

  19. Drug abuse among the students

    Muhammad Zaman

    2015-01-01

    Full Text Available ABSTRACT:Drug abuse is the willful misuse of either licit or illicit drugs for the purpose of recreation, perceived necessity or convenience. Drug abuse is a more intense and often willful misuse of drugs often to the point of addiction. In the eastern world the incidence shows a decline or a static pattern but the number of drug addicts is still enormous.. The major drug of abuse are heroin and marijuana but designer drugs are shown to be on the increase. The aim of the study is to determine the ratio of the drug abuse in student. For this purpose we selected different institutions including “the university of Lahore”, “Forman Christian college”(private sector and Punjab university(Govt sector and conducted survey in 500 student. High proportion of students was found abusing drugs. From this study, we came across multiple factors which are the main cause of drug abuse in medical student including depression, anxiety, schizophrenia, as well as personality disorder like antisocial personality disorder. The most commonly abused drugs include stimulants, opioids, and benzodiazepines, antihistamines. Although survey have indicated high rate of illicit and prescription drugs misuse among college students, few have assessed the negative consequences, personel concerns, or interest in intervention for drugs use. Drug abuse although regarded as a personality disorder, may also be seen as worldwide epidemic with evolutionary genetic, physiology and environmental influences Controlling and affecting human behavior. Globally, the use has reached all time high. The study showed males are more drug abusers as compared to females. The drug abuse ratio in students of private sector is more as compared to Govt sector.

  20. Child abuse in panic disorder

    Bonevski Dimitar

    2008-01-01

    Full Text Available Introduction Numerous authors associate child abuse with serious long-term consequences to the general and psychological well-being in particular. Clinical research to date reveals strong correlation between childhood abuse and neglect and anxiety disorders, especially panic disorder. Material and Methods This study was conducted in order to assess the level of emotional, physical and sexual childhood abuse as well as the physical and emotional childhood neglect in 40 adult patients suffering from panic disorder, diagnosed in accordance with the 10th International Classification of Disorders diagnostic criteria, compared with the control group of 40 healthy test subjects without a history of psychiatric disorders, using the Childhood Trauma Questionnaire. The severity of the clinical manifestation in patients with panic disorder was assessed using the Panic Disorder Severity Scale. Results and Discussion There were no significant differences between the groups as to the level of sexual abuse and physical neglect, whereas in the group of patients with panic disorder, the level of physical and emotional abuse was significantly higher, with emphasis on emotional neglect. With regards to the correlation between the severity of the clinical manifestation in patients with panic disorder and the severity of suffered abuse and neglect in childhood age, significant correlation was found in the physical and emotional abuse as well as emotional neglect. There was no significant correlation in the aspect of the physical neglect and sexual abuse. Conclusion Our research underlines the importance of childhood physical abuse, and especially emotional abuse and emotional neglect in the occurrence of panic disorder later in life.

  1. [Child abuse in the family].

    De Almeida, Helena Nunes; André, Isabel Margarida; De Almeida, Ana Nunes

    2002-01-01

    The objective of this study is to carry out a current survey of the situation of child abuse in the family. It is based on a national survey conducted in 1996, which was addressed to childcare professionals (in the areas of health, education and social services). This survey was based, on the one hand, on a wide-ranging definition of child abuse, including within it not just active forms of physical and psychic violence against the child, but also forms of (both material and affective) privation, omission or negligence which affect the child's growth and development. On the other hand, this study also favoured a contextual approach to child abuse. 1,126 institutions in Portugal were contacted and 755 valid survey responses were received. This report outlines some of the results obtained, namely by providing a description of the sample of the 755 child abuse victims, the respective social and family contexts to which they and the aggressors belong, as well as the types of abuse which have been committed against them; and a typology of forms of abuse and negligence, describing not just the internal aspects that make up child abuse directly, but also its relationship to the child's social and family contexts of belonging. The typology was derived from the statistical handling of the data gathered (factorial analysis of multiple matches, followed by a hierarchical analysis into clusters). A number of key concepts are summarised in the conclusion. Children of all age groups and of both sexes, and from all types of families and social backgrounds, regardless of their place in the phratry, are subject to abuse in Portugal. But different types of abuse and negligence are associated with the contexts to which the children and their families belong. Healthcare professionals are irreplaceable when it comes to detecting the wide variety of types of child abuse, and are an essential look-out post for two types of abuse which often slip through the net of other professionals

  2. Spiritual abuse: an additional dimension of abuse experienced by abused Haredi (ultraorthodox) Jewish wives.

    Dehan, Nicole; Levi, Zipi

    2009-11-01

    This article aims to conceptualize spiritual abuse as an additional dimension to physical, psychological, sexual, and economic abuse. Growing out of an interpretivist participatory action research study in a therapeutic Haredi (Jewish ultraorthodox) group of eight abused women, spiritual abuse has been defined as any attempt to impair the woman's spiritual life, spiritual self, or spiritual well-being, with three levels of intensity: (a) belittling her spiritual worth, beliefs, or deeds; (b) preventing her from performing spiritual acts; and (c) causing her to transgress spiritual obligations or prohibitions. The concept and its typology are illustrated by means of examples from the women's abusive experiences and may be of theoretical and therapeutic worldwide relevance. PMID:19809096

  3. Disseminated cysticercosis: a case report and review of the literature

    Bhalla Ashish; Sood Ashwani; Sachdev Atul; Varma Vandna

    2008-01-01

    Abstract Introduction Cysticercosis is a common tropical disease. One of the uncommon manifestations of cysticercosis is its disseminated form. Case presentation We report an immunocompetent patient with disseminated cysticercosis, who had involvement of the brain, subcutaneous tissues, skeletal muscles, right orbit and thyroid gland. In addition, this patient developed a serum sickness which responded to therapy. Conclusion Wide spread dissemination is a rare complication of cysticercosis. A...

  4. Disseminated varicella-zoster virus in an immunocompetent adult

    Petrun, Branden; Williams, Victoria; Brice, Sylvia

    2015-01-01

    Varicella-zoster is the virus that causes varicella (chicken pox), herpes zoster (shingles), and rarely, severe disseminated disease including diffuse rash, encephalitis, hepatitis, and pneumonitis. Disseminated disease is most often seen in immunocompromised patients. We describe a case of disseminated zoster in an immunocompentent patient who had previously been immune to VZV. This case is also unusual in that his clinical presentation was most consistent with varicella while his laboratory...

  5. Splenic hemangiosarcoma with abdominal dissemination in a dog

    GÜLBAHAR, M. Yavuz

    1998-01-01

    A case of spontaneosly ruptured splenic hemangiosarcoma with abdominal dissemination in a 12-year-old male German shepherd dog is described. At necropsy, a ruptured tumor mass was seen in the ventral region of the visceral surface of the spleen, and disseminated tumor masses were seen throughout the peritoneal cavity. Histologically, in both the primary tumor mass and dis-seminated tumor masses, atypical endothelial cells lining vascular spaces as small clefts or as cavernous channels were...

  6. Magnetic resonance imaging diagnosis of disseminated necrotizing leukoencephalopathy

    Disseminated necrotizing leukoencephalopathy is a rare syndrome of progressive neurologic deterioration seen most often in patients who have received central nervous system irradiation combined with intrathecal or systemic chemotherapy in the treatment or prophylaxis of various malignancies. Magnetic resonance imaging was more sensitive than computed tomography in detecting white matter abnormalities in the case of disseminated necrotizing leukoencephalopathy reported here. Magnetic resonance imaging may be useful in diagnosing incipient white matter changes in disseminated necrotizing leukoencephalopathy, thus permitting early, appropriate therapeutic modifications

  7. Child abuse, a case report

    Andri M.T. Lubis

    2004-03-01

    Full Text Available Child abuse is a pervasive social and medical problem that remains a major cause of disability and death among children. The annual incidence of abuse is estimated to be 15 to 42 cases per 1,000 children and appears to be increasing. Fractures are the second most common presentation of physical abuse after skin lesions, and approximately one third of abused children will eventually be seen by an orthopedic surgeon. We report a 7-month-old boy who was suspected to be abused. Our diagnosis was based on findings of multiple fractures, delay in seeking medical treatment and discrepancy between the history of illness and the clinical findings. He sustained multiple fractures in variety of healing, namely fractures on left supracondylar humeri, left radius and ulna, right radius and ulna, both femora, right tibia, and left tibia and fibula. Radiological examination was an important modality in revealing the possibility of abuse on this child. He had received medical treatment, protection, consultation team for the parents and an underway police investigation. (Med J Indones 2004; 13: 59-65 Keywords: child, abuse

  8. Self-Esteem and Attitudes toward Love in Abused and Non-Abused Women.

    Chambliss, Catherine; And Others

    This study sought to identify personality differences in abused versus non-abused women. Abused women (N=25) were from several centers for abused women and non-abused women (N=39) were students in evening psychology classes. All subjects completed Rubin's Love Scale, the abbreviated Dominance and Romanticism Scale, Rosenberg's Self-Esteem Scale,…

  9. The Genesis of Pedophilia: Testing the "Abuse-to-Abuser" Hypothesis.

    Fedoroff, J. Paul; Pinkus, Shari

    1996-01-01

    This study tested three versions of the "abuse-to-abuser" hypothesis by comparing men with personal histories of sexual abuse and men without sexual abuse histories. There was a statistically non-significant trend for assaulted offenders to be more likely as adults to commit genital assaults on children. Implications for the abuse-to-abuser…

  10. CUTANEOUS COMPLICATIONS OF INJECTION DRUG ABUSE

    Bimal; De, Anuradha; Sandeep Kumar

    2014-01-01

    Drug abuse is a worldwide problem with disastrous consequences for the patient, family and society at large. The case of injection drug abusers seems a little different as cutaneous complications may occur. Considering these complications the present article attempts to review the adverse effects of parenteral drug abuse on the skin including the common skin and soft tissue infections secondary to the drug abuse.

  11. Perceived Benefit from Child Sexual Abuse.

    McMillen, Curtis; And Others

    1995-01-01

    Studies adult perceptions of benefit from child sexual abuse in 154 low-income women who were sexually abused as children. Almost half reported some perceived benefit. Benefits fell into four main categories: protecting children from abuse, self-protection, increased knowledge of child sexual abuse, and having a stronger personality. Degree of…

  12. Child-Visiting and Domestic Abuse.

    Shepard, Melanie

    1992-01-01

    Explains problems with child visiting in cases of domestic abuse. Data on domestic abuse, child care concerns, and child adjustment problems were collected from 25 mothers and 22 fathers at a child visiting program serving separated and abusive families. Psychological abuse of mothers correlated with child adjustment problems. (BB)

  13. Childhood history of abuse and child abuse potential: the role of parent’s gender and timing of childhood abuse

    Romero-Martínez, Angel; Figueiredo, Bárbara; Moya-Albiol, Luis

    2014-01-01

    It has been suggested that being physically abused leads to someone becoming a perpetrator of abuse which could be associated to parents' gender, timing of the physical abuse and specific socio-demographic variables. This study aims to investigate the role the parents' gender, timing of childhood abuse and socio-demographic variables on the relationship between parents' history of childhood physical abuse and current risk for children. The sample consisted of 920 parents (414 fathers, 506 mot...

  14. Peripartum disseminated extrapulmonary tuberculosis simulating ovarian carcinoma.

    Sherer, David M; Osho, Joseph A; Zinn, Harry; Demetus, Spiro; Huang, Jennifer; Temkin, Sarah; Abulafia, Ovadia

    2005-10-01

    Disseminated extrapulmonary tuberculosis is an uncommon complication of pregnancy. We present a 26-year-old multiparous immigrant from Haiti who was admitted following an extramural preterm delivery. Marked ascites was confirmed by computerized tomography, which also revealed a thickened greater omentum. These findings were considered suggestive of advanced ovarian carcinoma, although extrapulmonary tuberculosis was also considered despite negative tuberculin skin test screening. Image-guided omental biopsy demonstrated caseating granulomas substantiating the diagnosis of abdominal tuberculosis, which was later confirmed by cultures. The patient responded well to antituberculosis medications. This case describes the unusual peripartum presentation of abdominal tuberculosis simulating advanced ovarian carcinoma, and demonstrates the importance of considering extrapulmonary tuberculosis when encountering ascites and omental thickening during pregnancy despite negative tuberculin skin test screening. PMID:16215926

  15. Multilocular disseminated tarlov cysts: importance of imaging.

    Padma, Subramanyam; Sundaram, P Shanmuga

    2014-01-01

    With technological advancements and wider availability of multimodality imaging, incidental lesions are frequently identified in patients undergoing various imaging studies. We report here a case of multiloculated disseminated perineural or Tarlov cysts (TCs). The primary aim of our study was to (1) provide a comprehensive review of the clinical, imaging and histopathological features of TCs (2) to draw attention to the fact that multiple lumbo-sacral and dorsal TCs can produce nerve injuries and serious movement disturbances (3) to document the usefulness of the magnetic resonance imaging (MRI) and bone scan in noninvasive diagnosis and guiding management in such cases. These cysts are clearly identified by MR and computerized tomography imaging of the lumbosacral spine. However, there are no reports on the scintigraphic findings of TCs in literature. TCs are typically benign, asymptomatic lesions that can simply be monitored. Until date, no consensus exists about the best surgical strategy to be followed for their management. PMID:25191117

  16. Subcapsular sinus macrophages limit acute gammaherpesvirus dissemination.

    Frederico, Bruno; Chao, Brittany; Lawler, Clara; May, Janet S; Stevenson, Philip G

    2015-08-01

    Lymphocyte proliferation, mobility and longevity make them prime targets for virus infection. Myeloid cells that process and present environmental antigens to lymphocytes are consequently an important line of defence. Subcapsular sinus macrophages (SSMs) filter the afferent lymph and communicate with B-cells. How they interact with B-cell-tropic viruses is unknown. We analysed their encounter with murid herpesvirus-4 (MuHV-4), an experimentally accessible gammaherpesvirus related to Kaposi's sarcoma-associated herpesvirus. MuHV-4 disseminated via lymph nodes, and intranasally or subcutaneously inoculated virions readily infected SSMs. However, this infection was poorly productive. SSM depletion with clodronate-loaded liposomes or with diphtheria toxin in CD169-diphtheria toxin receptor transgenic mice increased B-cell infection and hastened virus spread to the spleen. Dendritic cells provided the main route to B-cells, and SSMs slowed host colonization, apparently by absorbing virions non-productively from the afferent lymph. PMID:25872742

  17. Data Dissemination in Mobile Computing Environment

    Dr A. Venugopal Reddy

    2009-07-01

    Full Text Available Data dissemination in asymmetrical communicationenvironment, where the downlink communication capacity ismuch greater than the uplink communication capacity, is bestsuited for mobile environment. In this architecture there will bea stationary server continuously broadcasting different dataitems over the air. The mobile clients continuously listen to thechannel and access the data of their interest whenever itappears on the channel and download the same. The typicalapplications of such architecture are stock market information,weather information, traffic information etc. The importantissue that is to be addressed in this type of data disseminationis – how quickly the mobile clients access the data item of theirinterest i.e. minimum access time so that the mobile clients savethe precious battery power while they are on mobile. Thispaper reviews the various techniques for achieving theminimum access time. The advantages and disadvantages arediscussed and explored different research areas for achievingthe minimum access time.

  18. Alpha particles for treatment of disseminated melanoma

    Link, E.M. [London Univ. (United Kingdom)

    2010-11-15

    Invading melanoma spreads to local and unpredictable distant location at the early stages of its development. It is justifiable, therefore to classify the disease as a systemic disorder. This requires a systemic treatment that reaches all melanoma cells irrespective of whether they are singly dispersed and in circulation or already forming solid tumours of various sizes. Targeted radiotherapy affects directly and selectively cancer cells provided an appropriate radionuclide and its carrier are chosen. Melanoma is a pigmented tumour. Methylene blue (MTB) accumulates selectively in melanoma cells due to its exceptionally high affinity to melanin. MTB serves, therefore, as a carrier for radionuclides. {sup 211}At-MTB has proved to be particularly effective in treating disseminated melanoma when administered systemically and, at the same time, non-toxic to normal non-pigmented and pigmented organs. (author)

  19. Alpha particles for treatment of disseminated melanoma

    Link, E.M. [London University (United Kingdom)

    2010-07-01

    Invading melanoma spreads to local and unpredictable distant location at the early stages of its development. It is justifiable, therefore, to classify the disease as a systemic disorder. This requires a systemic treatment that reaches all melanoma cells irrespective of whether they are singly dispersed and in circulation or already forming solid tumours of various sizes. Targeted radiotherapy affects directly and selectively cancer cells provided an appropriate radionuclide and its carrier are chosen. Melanoma is a pigmented tumour. Methylene blue (MTB)) accumulates selectively in melanoma cells due to its exceptionally high affinity to melanin. MTB serves, therefore, as a carrier for radionuclides. {sup 211}At-MTB has proved to be particularly effective in treating disseminated melanoma when administered systemically and, at the same time, non-toxic to normal non-pigmented and pigmented organs. (authors)

  20. Ventricular metastasis resulting in disseminated intravascular coagulation

    Davis Ian D

    2005-05-01

    Full Text Available Abstract Background Disseminated Intravascular Coagulation (DIC complicates up to 7% of malignancies, the commonest solid organ association being adenocarcinoma. Transitional Cell Carcinoma (TCC has rarely been associated with DIC. Case presentation A 74-year-old woman with TCC bladder and DIC was found to have a cardiac lesion suspicious for metastatic disease. The DIC improved with infusion of plasma and administration of Vitamin K, however the cardiac lesion was deemed inoperable and chemotherapy inappropriate; given the patients functional status. We postulate that direct activation of the coagulation cascade by the intraventricular metastasis probably triggered the coagulopathy in this patient. Conclusion Cardiac metastases should be considered in cancer patients with otherwise unexplained DIC. This may influence treatment choices.

  1. Collection, verification, sharing and dissemination of data

    Saarnak, Christopher; Utzinger, Jürg; Kristensen, Thomas K.

    2013-01-01

    that would enable all project partners to have access through a password protected Internet-based data portal. This required anonymous agreement on several common standardised sample forms, ranging from the mundane but important issue of using the same units of measurement to more complex challenges......The scientific community is charged with growing demands regarding the management of project data and outputs and the dissemination of key results to various stakeholders. We discuss experiences and lessons from CONTRAST, a multidisciplinary alliance that had been funded by the European Commission...... over a 4-year period, in order to optimize schistosomiasis control and transmission surveillance in sub-Saharan Africa. From the start, project partners from Europe and Africa set out an ambitious goal: to sample data following standard protocols at all field sites and then sharing the data in a way...

  2. Leisure and parties: Study on the dissemination of alcoholic drinks on university campuses

    Liana Abrão Romera

    2014-08-01

    Full Text Available The present study addresses the issue of alcohol consumption, emphasizing that persuasion to consumption can be observed in different contexts through advertising, mainly by posters put up at parties in university campuses. University parties represent one of the numerous forms of leisure of young adults, and sociability, flirt, and entertainment are some marks of these festive contexts. Binge-drinking has also become part of these scenarios, sometimes abusively. Generally, the parties aimed at this public are publicized with posters scattered throughout college campuses in order to convince this public to adhere and participate. This study aimed to verify the persuasion to alcohol abuse, found in fliers and posters disseminating these parties, based on the arguments used. This qualitative descriptive study was developed by combining a methodological framework composed of bibliographic and documental analysis of 173 party posters, aimed at the young public, collected in universities in the state of Sao Paulo. The analysis indicates verbal and imagetic arguments that encourage excessive drinking. The apology to beverage consumption in leisure activities puts this field of study in an important place for analyzing the behaviors experienced in it, especially by youth groups. The results represent an important step for the understanding of new modes of alcohol consumption, occupation and experience of leisure, and alert to the evelopment of prevention programs directed to this public and specific spaces.

  3. [Upgrade on alcohol abuse].

    Bordini, L; Riboldi, L

    2010-01-01

    Problematic use of alcohol configures an element of interest in the context of preventive interventions aimed to ensuring the performance of any work in safety conditions. To contrast the acute alcohol abuse in the workplace the existing legislation provides alcoholimeters controls and prohibition of recruitment and administration of alcohol. Recent legislation (D.Lgs. 81/08) establishes health surveillance for alcohol dependence and appears still incomplete and difficult to apply. Clinical diagnostic tools available to the physician for alcohol dependence identification are well-defined and recently improved thanks to new laboratory markers with high sensitivity and specificity (CDT) and self-administered questionnaires. In this contest we are awaiting for legislative action to specify conditions and procedures for inspections in the workplace in order to face the problem of alcohol dependence without excessive bureaucracy and with more attention to preventive aspects. PMID:21438261

  4. Connecting network properties of rapidly disseminating epizoonotics.

    Ariel L Rivas

    Full Text Available To effectively control the geographical dissemination of infectious diseases, their properties need to be determined. To test that rapid microbial dispersal requires not only susceptible hosts but also a pre-existing, connecting network, we explored constructs meant to reveal the network properties associated with disease spread, which included the road structure.Using geo-temporal data collected from epizoonotics in which all hosts were susceptible (mammals infected by Foot-and-mouth disease virus, Uruguay, 2001; birds infected by Avian Influenza virus H5N1, Nigeria, 2006, two models were compared: 1 'connectivity', a model that integrated bio-physical concepts (the agent's transmission cycle, road topology into indicators designed to measure networks ('nodes' or infected sites with short- and long-range links, and 2 'contacts', which focused on infected individuals but did not assess connectivity.THE CONNECTIVITY MODEL SHOWED FIVE NETWORK PROPERTIES: 1 spatial aggregation of cases (disease clusters, 2 links among similar 'nodes' (assortativity, 3 simultaneous activation of similar nodes (synchronicity, 4 disease flows moving from highly to poorly connected nodes (directionality, and 5 a few nodes accounting for most cases (a "20:80" pattern. In both epizoonotics, 1 not all primary cases were connected but at least one primary case was connected, 2 highly connected, small areas (nodes accounted for most cases, 3 several classes of nodes were distinguished, and 4 the contact model, which assumed all primary cases were identical, captured half the number of cases identified by the connectivity model. When assessed together, the synchronicity and directionality properties explained when and where an infectious disease spreads.Geo-temporal constructs of Network Theory's nodes and links were retrospectively validated in rapidly disseminating infectious diseases. They distinguished classes of cases, nodes, and networks, generating information usable

  5. Intracranial germinoma with ventricular system dissemination

    Shi-yun CHEN

    2014-05-01

    Full Text Available Objective To study the clinical, neuroimaging and histopathological features of intracranial germinoma.  Methods One case of intracranial germinoma with ventricular system dissemination was reported, and related literatures were reviewed.  Results A 34-year-old male complained of progressive dizziness for 30 d and manifested unsteady gait for 45 d. Radiological examinations revealed low signal intensity on T1WI and hyperintense on T2WI in the corpus callosum, left cerebellum, around the fourth ventricle, aqueduct mesencephalon, the ventral pons and pineal region, with even or uneven enhancement after contrast. The clinical initial diagnosis was "intracranial multiple focal lesions and high possibility of multiple sclerosis". After well response to glucocorticoid impact and dehydration, the patient stopped taking drugs but presented relapse and exacerbation. Later, he underwent biopsy on pineal region and was diagnosed as intracranial germinoma. Microscopically, the big germ cells and lymphocytes coexisted. Tumor cells were epithelioid cells with transparent cytoplasm, prominent nuclei and mitotic activity. Lymphocytes were distributed along interstitial substance of vessel and fiber, and individual syncytiotrophoblasts were sprasely distributed. Immunohistochemical staining showed tumor cells were positive for CD117 and OCT3/4, and the syncytiotrophoblasts were positive for β-human chorionic gonadotropin ( β-hCG. The clinical symptoms were completely alleviated after radiotherapy and chemotherapy.  Conclusions Because of the sensitivity for radiotherapy and chemotherapy, intracranial germinoma can be diagnosed and treated early to improve its prognosis. However, it is very easy to disseminate along with ventricular system and form multiple lesions, leading to atypical clinical and imaging manifestations, which is a big challenge for clinical diagnosis. doi: 10.3969/j.issn.1672-6731.2014.05.010

  6. Childhood Deaths from Physical Abuse.

    Kasim, Mohd. Sham; and Others

    1995-01-01

    This paper describes 30 cases of childhood deaths caused by physical abuse in Kuala Lumpur, Malaysia. Data presented include ethnic origins, age, causes of death, identity of perpetrators, and marital situation of parents. (DB)

  7. Understanding Drug Abuse and Addiction

    ... as family disintegration, loss of employment, failure in school, domestic violence, and child abuse. What Is Drug Addiction? Addiction is a chronic, often relapsing brain disease that causes compulsive drug seeking and use, despite harmful consequences ...

  8. The Prognosis of Child Abuse

    Lynch, Margaret A.

    1978-01-01

    Reviews the prognosis for abused children in terms of death, re-injury, permanent physical damage, growth failure, intellectual retardation, and personality and behavior problems. Discusses problems of collecting data and inadequacies of intervention treatments. (JB)

  9. Child neglect and emotional abuse

    ... emotionally abused. They may have: Problems in school Eating disorders, leading to weight loss or poor weight gain Emotional issues such as low self-esteem, depression, and anxiety Extreme behavior such as acting ...

  10. Personality development after physical abuse.

    Oates, R K

    1984-01-01

    Personality development after child abuse was studied in 39 children who had, on average, been admitted to hospital five and a half years previously. In contrast to a control group, the abused children had fewer friends, lower ambitions, and lower self esteem. They were more serious, shy, and subdued on a personality assessment and were more likely than the control children to have behaviour disturbances recorded on a questionnaire for teachers. Their mothers also noted a higher incidence of ...

  11. Understanding URL Abuse for Profit

    Chachra, Neha

    2015-01-01

    Large-scale online scam campaigns pose a significant security threat to casual Internet users. Attackers simultaneously abuse millions of URLs to swindle visitors by selling counterfeit goods, by phishing to steal user credentials for various online services, or even by infecting user machines with malware. In this dissertation, I address the problem of studying these large-scale fraudulent ecosystems that heavily rely on URL abuse for profit. I demonstrate the feasibility of analyzing ground...

  12. The sexually abused battered child.

    Hobbs, C J; Wynne, J M

    1990-01-01

    A total of 130 children were identified in whom both evidence of sexual abuse and non-accidental, non-genital physical injuries (bruises, fractures, scratches, burns and scalds, including failure to thrive) were found. There were 77 girls and 53 boys with mean ages 5.7 and 6.8 years respectively and the peak age between the second and seventh birthdays; this reflects previous reports indicating that physical and sexual abuse predominantly involves young children. Patterns of injury that sugge...

  13. Attitudes towards child sexual abuse

    Tennfjord, Oddfrid Skorpe

    2008-01-01

    The main purpose of the present thesis was to develop a measurement instrument aimed to reveal attitudes towards child sexual abuse, and to measure attitudes and associating personal, social and cultural factors among three different samples of Norwegian adults. Additional aims were to explore the relation between participants’ knowledge-seeking on the one hand, their experiences, attitudes and actual knowledge about abuse on the other hand.Three studies are presented based on the same data m...

  14. Child Abuse and Disabled Children

    Obilade, Titilola T.

    2004-01-01

    Abstract for presentation given at the Annual General Scientific Meeting/Workshop of the Medical Women’s Association of Nigeria in Lagos, Nigeria, on December 28, 2004. Children with disabilities are a population at a higher risk of abuse and maltreatment. Studies have shown that children with disabilities are 3.4 times more likely to be abused than nondisabled peers. These disabilities include children who are visually-impaired, hearing-impaired, chronically-ill, developmentally ...

  15. Disseminated Fusarium infection in autologous stem cell transplant recipient

    Vivian Iida Avelino-Silva; Jessica Fernandes Ramos; Fabio Eudes Leal; Leonardo Testagrossa; Yana Sarkis Novis

    2015-01-01

    Disseminated infection by Fusariumis a rare, frequently lethal condition in severely immunocompromised patients, including bone marrow transplant recipients. However, autologous bone marrow transplant recipients are not expected to be at high risk to develop fusariosis. We report a rare case of lethal disseminated Fusariuminfection in an autologous bone marrow transplant recipient during pre-engraftment phase.

  16. 48 CFR 3052.242-71 - Dissemination of contract information.

    2010-10-01

    ... prescribed in (HSAR) 48 CFR 3042.202-70, insert the following clause: Dissemination of Contract Information... performance of this contract, without the prior written consent of the Contracting Officer. An electronic or... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Dissemination of...

  17. Disseminated Fusariosis Occurring in Two Patients Despite Posaconazole Prophylaxis▿

    Bose, Prithviraj; Parekh, Hiral D.; Holter, Jennifer L.; Greenfield, Ronald A.

    2011-01-01

    Posaconazole is widely used for prophylaxis against invasive fungal infections in patients undergoing myeloablative therapy. Disseminated fusariosis is a serious invasive mold infection in such patients. Preclinical and clinical studies indicate activity of posaconazole against Fusarium. We describe two cases of disseminated fusariosis that occurred despite posaconazole prophylaxis.

  18. A novel case of canine disseminated aspergillosis following mating

    Walker, Jackson T.; Frazho, Jean K.; Randell, Susan C.

    2012-01-01

    An intact bitch with a history of mating was presented with severe lameness and a vulvar discharge. A mixed lytic, proliferative tibial lesion and open pyometra were diagnosed. Bone biopsy and uterine culture revealed disseminated aspergillosis. This is the first report of Aspergillus pyometra with dissemination following mating in the dog.

  19. Disseminated aspergillosis in an adolescent with acute lymphoblastic leukemia.

    Zwitserloot, A.M.; Warris, A.; Hek, L.G.F.M. van 't; Die, LE van; Verweij, P.E.; Mavinkurve-Groothuis, A.M.C.

    2008-01-01

    Disseminated aspergillosis in immunocompromised patients has a mortality rate of almost 100%. Despite the development of new antifungal agents, the outcome of disseminated aspergillosis has only improved slightly, particular in patients with central nervous system (CNS) involvement. The use of combi

  20. Drug abuse in slum population.

    Ghulam, Ram; Verma, Kamal; Sharma, Pankaj; Razdan, Monica; Razdan, Rahul Anand

    2016-01-01

    Substance abuse is an important health problem throughout the world including India, but prevalence and pattern of abuse varies from country to country and in different types of population. Slums have their own social and economic problems so that substance abuse may be different in this population and might be related with these problems. The aim of the present study was to study the prevalence and pattern substances in slum population. Prakash Chandra Sethi Nagar slum area of Indore district was selected for the purpose of this study. In first phase of the study, first a camp was organized to sensitize local leaders, key persons, and local inhabitants about drug abuse at Chandra Prakash Sethi Nagar. After that basic information was gathered with the key persons in Chandra Prakash Sethi Nagar. In second phase by house-to-house survey, all members of the family were interviewed in detail and information was recorded on semi-structured proforma. We observed prevalence rate of 560/1000 populations, 78.2% were males, 28.2% were females, and two-third abusers were laborers (72%). In order of frequency, tobacco was the most common substance abused in 53.9% population followed by gutka (nontobacco pan masala). Other drugs in order of frequency were alcohol 46.5%, cannabis 8.9%, opiates 4.9%, sedative and hypnotic 2.0%, solvents 1.0%, and cocaine in 0.1%. Slum population has higher prevalence rates than general population. PMID:26985110

  1. Aerial Dissemination of Clostridium difficile spores

    Banfield Kathleen R

    2008-01-01

    Full Text Available Abstract Background Clostridium difficile-associated diarrhoea (CDAD is a frequently occurring healthcare-associated infection, which is responsible for significant morbidity and mortality amongst elderly patients in healthcare facilities. Environmental contamination is known to play an important contributory role in the spread of CDAD and it is suspected that contamination might be occurring as a result of aerial dissemination of C. difficile spores. However previous studies have failed to isolate C. difficile from air in hospitals. In an attempt to clarify this issue we undertook a short controlled pilot study in an elderly care ward with the aim of culturing C. difficile from the air. Methods In a survey undertaken during February (two days 2006 and March (two days 2007, air samples were collected using a portable cyclone sampler and surface samples collected using contact plates in a UK hospital. Sampling took place in a six bedded elderly care bay (Study during February 2006 and in March 2007 both the study bay and a four bedded orthopaedic bay (Control. Particulate material from the air was collected in Ringer's solution, alcohol shocked and plated out in triplicate onto Brazier's CCEY agar without egg yolk, but supplemented with 5 mg/L of lysozyme. After incubation, the identity of isolates was confirmed by standard techniques. Ribotyping and REP-PCR fingerprinting were used to further characterise isolates. Results On both days in February 2006, C. difficile was cultured from the air with 23 samples yielding the bacterium (mean counts 53 – 426 cfu/m3 of air. One representative isolate from each of these was characterized further. Of the 23 isolates, 22 were ribotype 001 and were indistinguishable on REP-PCR typing. C. difficile was not cultured from the air or surfaces of either hospital bay during the two days in March 2007. Conclusion This pilot study produced clear evidence of sporadic aerial dissemination of spores of a clone of C

  2. DDDRC: decentralised data dissemination in VANET using raptor codes

    Kumar, Rakesh; Dave, Mayank

    2015-06-01

    The design of data dissemination protocol has been a great challenge due to the highly dynamic and unreliable wireless channel in vehicular ad hoc networks (VANET). In literature, several interesting solutions are proposed to perform data dissemination for this environment. But these solutions either use architectures requiring centralised coordination or global network knowledge or large intermediate buffers. In this paper, we propose a decentralised technique that overcomes above requirements and provides reliable and scalable communication in both dense and sparse traffic for VANET. Random walks are used in the proposed technique to disseminate data from one vehicle to other vehicles in the network. We use raptor codes to provide low decoding complexity and more scalability for data dissemination. Simulation results demonstrate that the proposed technique has better fault tolerance with lower complexity than general random-walk-based dissemination process and more scalability as compared to the other protocols.

  3. DISSEMINATION OF AND USE OF HIV/AIDS INFORMATION BY STUDENTS AT THE UNIVERSITY OF BOTSWANA

    Lauretta Wamunza

    2007-10-01

    Full Text Available Presents part of the findings of a study that was carried out at the University of Botswana to determine in general how HIV/AIDS information is disseminated to and used by undergraduate students. Both qualitative and quantitative approaches were used. A survey design was used to study a population of 9000 plus undergraduate students. Questionnaires and interviews were used to collect data. SPSS was used to analyse quantitative data while qualitative data was analysed using thematic categorization.Key findings revealed that the HIV/AIDS information disseminated to students include information on behaviour change; information on HIV/AIDS prevention; transmission and treatment. The means of disseminating information to students include the use of multiple channels such as the university Health and Wellness Centre, Lectures, peer groups, seminars/workshops, students meetings, the University Clinic and the library. The study found that the most common media used to disseminate information to students include video, print, CDs and verbal means. Finally, factors that affect access to and use of HIV/AIDS information by students include: religious orientations, substance abuse, low income levels, multiple relationships, age and gender.There is need for the University of Botswana to review its overall approach of disseminating HIV/AIDS information to students in order to make it more effective. Moreover, strong liaison among agencies involved in the fight against the spread of HIV/AIDS at the University is needed. Furthermore, a more rigorous research into issues of students’ attitudes and values in relation to HIV/AIDS is needed. Similarly, more efforts are needed to create awareness and educate students on the dangers associated with substance abuse, multiple partners and practicing unprotected sex. The need to encourage testing for HIV/AIDS among students is needed so that appropriate interventions can be put in place.The world over, HIV/AIDS has

  4. Developing Agency Dissemination Policy. Washington State Dissemination Conference, Office of the Superintendent of Public Instruction (Olympia, Washington, January 22, 1980).

    Northwest Regional Educational Lab., Portland, OR.

    Building upon groundwork established by previous meetings, this session of the Washington Dissemination Task Force focused on the preparation and intensive study of a policy and guidelines on dissemination for the Office of the State Department of Public Instruction (OSPI), and the identification of future responsibilities of the group. Conference…

  5. Erythropoietin use and abuse.

    John, M Joseph; Jaison, Vineeth; Jain, Kunal; Kakkar, Naveen; Jacob, Jubbin J

    2012-03-01

    Recombinant human erythropoietin (rhEPO) is arguably the most successful therapeutic application of recombinant DNA technology till date. It was isolated in 1977 and the gene decoded in 1985. Since then, it has found varied applications, especially in stimulating erythropoiesis in anemia due to chronic conditions like renal failure, myelodysplasia, infections like HIV, in prematurity, and in reducing peri-operative blood transfusions. The discovery of erythropoietin receptor (EPO-R) and its presence in non-erythroid cells has led to several areas of research. Various types of rhEPO are commercially available today with different dosage schedules and modes of delivery. Their efficacy in stimulating erythropoiesis is dose dependent and differs according to the patient's disease and nutritional status. EPO should be used carefully according to guidelines as unsolicited use can result in serious adverse effects. Because of its capacity to improve oxygenation, it has been abused by athletes participating in endurance sports and detecting this has proved to be a challenge. PMID:22470858

  6. Erythropoietin use and abuse

    M Joseph John

    2012-01-01

    Full Text Available Recombinant human erythropoietin (rhEPO is arguably the most successful therapeutic application of recombinant DNA technology till date. It was isolated in 1977 and the gene decoded in 1985. Since then, it has found varied applications, especially in stimulating erythropoiesis in anemia due to chronic conditions like renal failure, myelodysplasia, infections like HIV, in prematurity, and in reducing peri-operative blood transfusions. The discovery of erythropoietin receptor (EPO-R and its presence in non-erythroid cells has led to several areas of research. Various types of rhEPO are commercially available today with different dosage schedules and modes of delivery. Their efficacy in stimulating erythropoiesis is dose dependent and differs according to the patient′s disease and nutritional status. EPO should be used carefully according to guidelines as unsolicited use can result in serious adverse effects. Because of its capacity to improve oxygenation, it has been abused by athletes participating in endurance sports and detecting this has proved to be a challenge.

  7. Disseminated intravascular coagulation following administration of sunitinib

    OLIVO, ANAËLLE; NOËL, NICOLAS; BESSE, BENJAMIN; TABURET, ANNE-MARIE; LAMBOTTE, OLIVIER

    2016-01-01

    Sunitinib is an increasingly used, orally administered targeted therapy, approved by the European Medicines Agency for the treatment of various types of cancer, including gastrointestinal stromal tumor unresectable or metastatic disease, following disease progression or intolerance to imatinib, and advanced or metastatic renal cell carcinoma, progressive well-differentiated pancreatic neuroendocrine tumors in patients with unresectable, locally advanced or metastatic disease. Sunitinib inhibits several tyrosine kinases, including the vascular endothelial growth factor receptor and the platelet-derived growth factor receptor. Tyrosine kinases inhibitor therapies are generally well-tolerated; nonetheless, they are not void of side effects. The majority of patients reported are grade 1 or 2, and include common and unspecific adverse events, including fatigue, gastrointestinal disorders, skin discoloration, altered taste, cough and dyspnea. Grade 3 or 4 adverse events, including bleeding and hemorrhage, are less frequent. The present study presented the first case of disseminated intravascular coagulation associated with the administration of sunitinib, shortly following the increase of sunitinib dosage. PMID:27330781

  8. Vasogenic edema characterizes pediatric acute disseminated encephalomyelitis

    MR imaging criteria for diagnosing acute disseminated encephalomyelitis (ADEM) have not been clearly established. Due to the wide spectrum of differential considerations, new imaging features allowing early and accurate diagnosis for ADEM are needed. We hypothesized that ADEM lesions would be characterized by vasogenic edema due to the potential reversibility of the disease. Sixteen patients who met the diagnostic criteria for ADEM proposed by the International Pediatric Multiple Sclerosis Study Group (IPMSSG) and had complete MR imaging studies performed at our institution during the acute phase of the disease were identified retrospectively and evaluated by experienced pediatric neuroradiologists. Vasogenic edema was demonstrated on diffusion-weighted imaging (DWI) and corresponding apparent diffusion coefficient (ADC) maps in 12 out of 16 patients; cytotoxic edema was identified in two patients while the other two patients displayed no changes on DWI/ADC. ADC values for lesions and normal-appearing brain tissue were 1.39 ± 0.45 x 10-3 and 0.81 ± 0.09 x 10-3 mm/s2, respectively (p = 0.002). When considering a cutoff of 5 days between acute and subacute disease, no difference between ADC values in acute vs. subacute phase was depicted. However, we found a significant correlation and an inverse and significant relationship between time and ADC value. We propose that vasogenic edema is a reliable diagnostic sign of acute neuroinflammation in ADEM. (orig.)

  9. Dissemination and experience with cognitive processing therapy

    Kathleen M. Chard, PhD

    Full Text Available Clinical practice guidelines suggest that cognitive behavioral therapies are recommended for the treatment of posttraumatic stress disorder (PTSD. One of these treatments, cognitive processing therapy (CPT, is an evidence-based treatment that has been shown to be effective at treating combat, assault, and interpersonal violence trauma in randomized controlled trials. The Department of Veterans Affairs (VA Office of Mental Health Services has implemented an initiative to disseminate CPT as part of a broad effort to make evidence-based psychotherapies widely available throughout the VA healthcare system. This article provides an overview of CPT and reviews the efficacy and program evaluation data supporting its use in a variety of settings. In addition, we report on survey data from individuals who have participated in the VA initiative and on outcome data from patients treated by rollout-trained therapists. Our data suggest that many clinicians trained in the rollout show good adoption of the CPT model and demonstrate solid improvements in their patients’ PTSD and depressive symptomotology. Finally, we offer recommendations for using CPT in clinical settings.

  10. Modeling news dissemination on nuclear issues

    Reis Junior, Jose S.B.; Barroso, Antonio C.O.; Menezes, Mario O., E-mail: jsbrj@ime.usp.b, E-mail: barroso@ipen.b, E-mail: mario@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    Using a modified epidemiological model, the dissemination of news by media agents after the occurrence of large scale disasters was studied. A modified compartmented model was developed in a previous paper presented at INAC 2007. There it used to study to the Chernobyl's nuclear accident (1986) and the Concorde airplane crash (2000). Now the model has been applied to a larger and more diverse group of events - nuclear, non-nuclear and naturally caused disasters. To be comprehensive, old and recent events from various regions of the world were selected. A more robust news repository was used, and improved search techniques were developed to ensure that the scripts would not count false positive news. The same model was used but with improved non-linear embedded simulation optimization algorithms to generate the parameters of interest for our model. Individual parameters and some specific combination of them allow some interesting perceptions on how the nature of the accident / disaster gives rise to different profiles of growth and decay of the news. In our studies events involving nuclear causes generate news repercussion with more explosive / robust surge profiles and longer decaying tails than those of other natures. As a consequence of these differences, public opinion and policy makers are also much more sensitive to some issues than to others. The model, through its epidemiological parameters, shows in quantitative manner how 'nervous' the media content generators are with respect to nuclear installations and how resilient this negative feelings about nuclear is. (author)