International Nuclear Information System (INIS)

The study compares the doses absorbed by the dentomaxillary area in spiral CT and panoramic examinations. The dose measurements demonstrate that patients receive smaller doses with panoramic radiography than with spiral CT with Dentascan. After following for some variations from instrumental differences, they are in substantial agreement with literature data. Further investigations are needed considering the radiobiological risk related to the growing spread of Dentascan examinations.

International Nuclear Information System (INIS)

The distribution of the central benzodiazepine receptor specific ligand iodine-123 iomazenil was investigated in seven human adults from whole-body scans, blood samples and urine collected up to 24 h after injection. Using 12 source organs, the MIRD method was applied to calculate the absorbed radiation dose of the radioligand in various organs. The urinary bladder wall (0.15 mGy/MBq), lower large intestinal wall (0.071 mGy/MBq) testes (0.044 mGy/MBq) and upper large intestined wall (0.038 mGy/MBq) received the highest absorbed doses. The average effective dose equivalent of "1"2"3I-IBZM for adults was estimated to be 0.033 mSv/MBq. (orig.).

CERN Document Server

Determination of absorbed dose in a patient irradiated by beams of x or gamma rays in radiotherapy procedures

Energy Technology Data Exchange (ETDEWEB)

The concept of a multi-cavity volumetric solar receiver is very attractive for the profitability of certain of its characteristics such as high efficiency and economy. The absorber is based on a pack of small ceramic cavities which intercept and absorb the inherent high solar flux reflected from an array of mirrors. Atmospheric air acts as a coolant medium when it is drawn through the pack. A model for an overall heat transfer performance of the receiver is given and numerically solved.

Science.gov (United States)

This invention is an improved solar energy cavity receiver for exposing materials and components to high temperatures. The receiver includes a housing having an internal reflective surface defining a cavity and having an inlet for admitting solar radiation thereto. A photothermal absorber is positioned in the cavity to receive radiation from the inlet. A reflective baffle is positioned between the absorber and the inlet to severely restrict the re-radiation of energy through the inlet. The front surface of the baffle defines a narrow annulus with the internal reflective surface of the housing. The front surface of the baffle is contoured to reflect incoming radiation onto the internal surface of the housing, from which it is reflected through the annulus and onto the front surface of the absorber. The back surface of the baffle intercepts infrared radiation from ...

Energy Technology Data Exchange (ETDEWEB)

This invention is an improved solar energy cavity receiver for exposing materials and components to high temperatures. The receiver includes a housing having an internal reflective surface defining a cavity and having an inlet for admitting solar radiation thereto. A photothermal absorber is positiond in the cavity to receive radiation from the inlet. A reflective baffle is positioned between the absorber and the inlet to severely restrict the re-radiation of energy through the inlet. The front surface of the baffle defines a narrow annulus with the internal reflective surface of the housing. The front surface of the baffle is contoured to reflect incoming radiation onto the internal surface of the housing, from which it is reflected through the annulus and onto the front surface of the absorber. The back surface of the baffle intercepts radiation from the front ...

Energy Technology Data Exchange (ETDEWEB)

The study compares the doses absorbed by the dentomaxillary area in spiral CT and panoramic examinations. The dose measurements demonstrate that patients receive smaller doses with panoramic radiography than with spiral CT with Dentascan. After following for some variations from instrumental differences, they are in substantial agreement with literature data. Further investigations are needed considering the radiobiological risk related to the growing spread of Dentascan examinations. [Italian] Questo lavoro intende confrontare le dosi assorbite nel distretto dento-mascellare, con le due principali tecniche utilizzate in questo campo: TC spirale e ortopantomografia. Emerge come l'esame panoramico delle arcate dentarie eseguito con l'ortopantomografo comporti la'ssorbimento di dosi inferiori rispetto a quelle dell'esame TC spirale con programma ...

International Nuclear Information System (INIS)

While there have been many experimental and calculational investigations on absorbed dose distribution in the patient resulting from conventional X-ray procedures, such data for computerized tomography (CT) are still sparse. As this diagnostic procedure has shown a rapid increase in application during recent years, we have determined absorbed dose to body organs in a human phantom resulting from CT examinations. The exposure model consists of the heterogeneous MIRD-5 phantom and a suitable Monte-Carlo method to calculate absorbed dose to organs of interest. The exposure conditions are specified according to the exposure specifications of a CT-scanner currently in use. The calculations cover the range of body tissues of interest in terms of organ absorbed doses as well as a risk weighted absorbed ...

International Nuclear Information System (INIS)

Irradiation of the human body in diagnostic X-ray procedures results in different absorbed doses in the various body organs. A somatic dose index in formulated by applying the relative sensitivity of the human to each of the most important somatic effects and utilizing the absorbed dose in the affected organs. This quantity is used to convey a cumulative somatic impact and is computed for common radiographic views in diagnostic radiology as a function of beam quality for a nominal IR entrance exposure. Using typical X-ray beam qualities and exposures, the frequency of the various radiographic views that make up an examination and the frequencies of the various examinations in the national population, illustrative examples of the application of the somatic dose index are presented. (author).

British Library Electronic Table of Contents (United Kingdom)

Purpose Study the radiolysis of solid-state metoclopramide hydrochloride at various absorbed doses. Elucidate the structure of the degradation products to gain information on the radiolysis mechanisms. Methods Solid-state metoclopramide samples were irradiated at several doses with gamma rays and high-energy electrons to evaluate the influence of the dose rate. High-performance liquid chromatography with a diode array detector was used to measure the chemical potency as a function of the absorbed dose and to quantify the degradation products. The characterization of degradation products was performed by liquid chromatography/atmospheric pressure chemical ionization/tandem mass spectrometry. Results The degradation of solid-state metoclopramide after irradiation was negligible. No qualitati...

International Nuclear Information System (INIS)

When evaluating the risks of oncogenesis and cancer mortality following exposure to the radiations of the atomic bombs (A-bombs), the medical X-ray doses received by the A-bomb survivors must also be estimated and considered. Using a human phantom, dosimetry was performed to estimate the X-ray doses received by A-bomb survivors during medical examinations at the Radiation Effects Foundation (RERF) as part of the long-term follow-up on the Adult Health Study (AHS). These examinations have been estimated to represent nearly 45% of the survivors' cumulative medical irradiation dose. Doses to the salivary glands, thyroid gland, lung, breast, stomach and colon were measured using thermoluminescent dosemeters. The results, which are reported here, will aid in estimating organ doses received by individual AHS participants. ...

Energy Technology Data Exchange (ETDEWEB)

The receiver whose convective heat loss test results are presented was designed to absorb 5 MW of solar energy, using a molten salt working fluid. During the tests, this receiver was brought to a temperature of about 343 C by a small group of heliostats. Total receiver heat loss due to emitted radiation, conduction and convection was first determined, and the convection loss was established by calculating the radiation and conduction losses analytically and subtracting their sum from the total. Losses due to convection are found to be 1.43 percent of the total heat input.

International Nuclear Information System (INIS)

Wood-polymer composites (WPC) have been prepared of pinewood with different monomers using Gamma radiation: acrylamide, butyl acrylate, butyl methacrylate, styrene, acrylonitrile, and polyester. The polymer loading was determined as a function of monomer concentration and absorbed dose. The data show that polymer loading increases by increasing the monomer concentration. In two cases, BMA and polyester, the polymer loading decreases at high concentrations. This can be explained by the increase of the viscosity. Thus the diffusion of the compound into bulk would be slower. The absorbed dose seems to play a positive role in enhancing the polymer loading by increasing the dose. The mechanical properties, tensile and compression strength, have been improved in the most cases for all monomer concentrations or absorbed doses. Using polyester there ...

Energy Technology Data Exchange (ETDEWEB)

Depth dose distributions for protons in the energy range from 2 to 600 MeV have been calculated by Monte Carlo and analytical methods. The dependence on energy of Maximum Dose Equivalent (MDE), quality factor and isotropic factor recommended for practical use are presented. The problems connected with regulation of maximum permissible proton fluxes are discussed. (author).

International Nuclear Information System (INIS)

The Effective Dose Equivalent Concept defined by the International Commission on Radiological Protection in 1977 considers the risk from irradiation including both hereditary and somatic effects. This paper will deal with the definition of a concept for somatic effects only, the somatically significant dose equivalent. This is defined as the dose equivalent which if received by every member of the population, would be expected to produce the same total somatic injury to the population as does the actual dose equivalent received by various individuals. The somatically effective dose equivalent for a particular radiopharmaceutical is the weighted sum of the average dose equivalent to various organs. The dose equivalent to various organs can be derived from an extended MIRD formalism also considering ...

International Nuclear Information System (INIS)

The central benzodiazepine receptor tracer [N-methyl-"1"1C]iomazenil (Ro 16-0154) was synthesized by alkylation of the desmethyl precursor noriomazenil with ["1"1C]methyl iodide. The ["1"1C]CH_3I (prepared by reduction of ["1"1C]CO_2 with LiAlH_4 followed by reaction with HI) was reacted with noriomazenil inN,N -dimethylformamide and Bu_4N"+OH"- for 1 min at 80 deg. C and purified by HPLC (C_1_8, 34% CH_3CN/H_2O, 7 mL/min). The product was obtained with synthesis time 35 #+-# 5 min (mean #+-# SD, n = 7), radiochemical yield (EOB) 36 #+-# 16%, radiochemical purity 99 #+-# 1%, and specific activity 5100 #+-# 2800 mCi/#mu#mol. Absorbed radiation doses were calculated from previously acquired human biodistribution data. The urinary bladder wall received the highest dose (0.099 mGy/MBq) for 4.8 h voiding interval and the effective dose equivalent was 0.015 mSv/MBq. After i.v. injection ...

Energy Technology Data Exchange (ETDEWEB)

This report uses experimental data to compare the performance of two sodium cooled solar central receivers operated at the International Energy Agency Small Solar Power Systems project near Almeria, Spain. Performance includes point-in-time steady state efficiency, average efficiency, start-up time, and operation time. Point-in-time steady state efficiency calculations were based on the statistical method of least squares using receiver incident and absorbed powers. One receiver, a cavity type, showed a peak steady state receiver efficiency of 87% +- 5% and an average efficiency of about 67%. The other receiver, an external ''billboard'' type, had a peak steady state receiver efficiency of 96% +- 4% and an average efficiency of about 79%. The original design peak steady state efficiency predictions for ...

UK PubMed Central (United Kingdom)

PurposeTo determine the dosimetric impact of inter-fraction anatomical movements in prostate cancer patients receiving proton therapy.Full Text Available

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the accuracy of dose calculations by three algorithms. Depth dose, OPF (Output Factor) and dose profiles were measured in a heterogeneous phantom. These values were also calculated by three algorithms of the Batho power law (BPL), Equivalent-Tissue Air Ratio (ETAR) and Convolution superposition (CS). The data were obtained for 4, 6 and 10 MV photon beams with a linear accelerator (Varian 21EX). Field size ranged from 3 x 3 cm"2 to 10 x 10 cm"2. Dose profiles of beam penumbra were also measured by a 0.125 ml ionization chamber at the point of 8, 13 and 18 cm from the surface of the phantom at intervals of 1 mm. Differences between measured and calculated depth doses were within 2% in BPL and CS, but depth doses were overestimated in ETAR. OPFs were also overestimated with the error of more than 4% in ETAR. ...

International Nuclear Information System (INIS)

The National Radiological Protection Board is to carry out a survey of doses received by patients from the diagnostic use of X-rays, beginning in June 1977, and carried out at over 100 National Health Service hospitals. Details are given of the reasons for carrying out the survey and the survey objectives. The survey working methods are discussed, together with methods of calculation of the genetically significant dose. The radiation doses will be measured by a thermoluminescent dosimeter developed specially for the survey. (U.K.).

International Nuclear Information System (INIS)

Ionizing radiations that differ in number, size, and distribution of energy deposition events might be expected to cause different effects for the same absorbed dose. Furthermore, microdosimetry calculations suggest that large variations in biological effectiveness might be expected for internally deposited alpha-emitting radionuclides for the same absorbed dose, depending upon the specific activity and spatial distribution of the sources in tissue. The study described in this article was designed to demonstrate these phenomena in vitro. Cultured Chinese hamster ovary (CHO-K1 BH4) cells were exposed in vitro to inert, insoluble ceramic microspheres in zirconium dioxide labeled with "2"3"9Pu. The average exit energy of the 5.15 MeV alpha particle was calculated to be 4.3 MeV. Exposure times varied from four to seven hours to achieve the desired dose level.

International Nuclear Information System (INIS)

Carcinogenesis is now generally recognized to be an important detrimental effect in man after low dose irradiation. The carcinogenic action of ionizing radiation is clearly demonstrated after exposure to relatively high doses (in excess of 0.5 Gy) but for lower dose levels reliable direct observations are not available. With the introduction of special protocols for the performance of large scale screening programs by mammography the average absorbed dose in glandular tissue in the average breast can be restricted to a value of 3 mGy per mammogram. The risk for tumor induction after exposure to these low doses can never be established from human epidemiology. In order to investigate the risk of repeated exposure to small dose of ionizing radiation the induction of mammary tumors has been investigated in rats of the WAG/Rij strain after ...

International Nuclear Information System (INIS)

The decree refers to conditions of irradiation of food and its components for radappertization and radurization using gamma radiation from cobalt 60 or cesium 137, X radiation or electron beam up to maximum total medium absorbed dose 10 kGy.

International Nuclear Information System (INIS)

An attempt was made to quantify the radiation risk of diagnostic radiology. After a general introduction of terms as radiation damage, radiation risk and effective dose equivalent, based on publications of the ICRP, somatic dose indexes were computed for several radiologic investigations, that comprise organ doses committed to red bone marrow, lung, female breast and thyroid with and without considering the rest of the body. The dose for the rest of the body was assumed to be equal to the dose received by the red bone marrow, that is also distributed over the whole body. Neglecting the exposure of the rest of the body resulted in an insignificant increase in the estimated somatic risk, with its experimental determination not being necessary. (author).

Energy Technology Data Exchange (ETDEWEB)

To determine a suitable combination of X-ray filter and tube kilovoltage for Fuji Computed Radiography (FCR), provide better detection of pulmonary nodules, and reduce patient exposure, we compared observer performance with different X-ray filters and tube voltages. Radiographs were obtained with a copper filter backed by aluminium, with a tungsten filter backed by yttrium and aluminium, and with a lead filter backed by yttrium and aluminium, at both 100 kVp and 135 kVp. Observer performance in detecting simulated lung nodules, which were placed on the posterior aspect of a chest phantom, was compared using receiver operating characteristic (ROC) techniques for each combination of the X-ray filter and tube voltage. The results of the study indicated that (1) nodule detection was superior for the images obtained with 135 kVq as compared with 100 kVp; (2) approximately equal detection rates were obtained for the three X-ray filter sets, although results with the ...

Energy Technology Data Exchange (ETDEWEB)

Two neutron emesis experiments were conducted at the Armed Forces Radiobiology Research Institute (AFRRI). In both experiments (described as Phase I and Phase II) the radiation dose required to cause emesis in 50% of subjects (ED50) was determined for both neutron reactor and gamma reactor source radiation. Emesis onset, offset and duration times post-exposure are reported. Neutrons were maximized from the reactor by passing the beam through a 15.25 cm (6 in.) thick lead wall to filter out gamma photons. Gamma rays were maximized by thermalizing neutrons in 30.5 cm (12 in.) of water, then absorbing the thermal neutrons in a gadolinium-cadmium shield. In Phase I, 28 dogs were exposed to radiation: 12 were exposed to gamma photons at the rate of 0.69 Gy/min and 16 were exposed to neutrons at 1.2 Gy/min. In Phase II, 58 dogs in 3 groups were exposed to radiation: 19 were exposed in the gamma group at 0.75 Gy/min, 20 were exposed in the undrugged ...

International Nuclear Information System (INIS)

In areas where radiation dose monitoring has not been performed, it is essential to use material available in the environment be able to rapidly assess doses to individuals for immediate emergency medical care or for general estimation of the radiological consequences. It was shown that certain types of telephone cards containing microchips have the potential to be used as individual radiation dosimeters in emergency situations to detect doses over 250 mGy by luminescence measurements. In order to understand the dosimetric properties of chip cards, the components obtained from INFINIEON Company at various stages of production were used for luminescence measurements. It is found that the protecting layer used above the chips so called 'globe top' is the main source of radiation induced signal in chip cards. The globe top produced by INFINIEON at that stage is found to contain SiO2 and Epoxy. In order to improve the ...

International Nuclear Information System (INIS)

Doses to the salivary glands, thyroid gland, breast, lung, stomach and colon during mass radiological gastric screening, mass radiographic chest screening, upper gastrointestinal series and computed tomography were determined by exposing a female human phantom to simulated radiological X-ray examinations as performed in community hospitals. The doses were measured using thermoluminescent dosemeters, and the results will be used to document organ doses received by participants in the Atomic Bomb Casualty Commission/Radiation Effects Research Foundation Adult Health Study. (Author).

UK PubMed Central (United Kingdom)

Purpose:The oral chemotherapy cycle management program (CMP) provides clinical management support to patients receiving certain oral chemotherapies. The CMP includes a dose-monitoring...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

To date, no single passive detector has been found that measures dose equivalent from ionizing radiation exposure in low-Earth orbit. We have developed the I.S.S. Passive Dosimetry System (P.D.S.), utilizing a combination of TLD in the form of the self-contained Pille TLD system and stacks of CR-39 plastic nuclear track detector (P.N.T.D.) oriented in three mutually orthogonal directions, to measure total dose and dose equivalent aboard the International Space Station (I.S.S.). The Pille TLD system, consisting on an on board reader and a large number of Ca{sub 2}SO{sub 4}:Dy TLD cells, is used to measure absorbed dose. The Pille TLD cells are read out and annealed by the I.S.S. crew on orbit, such that dose information for any time period or condition, e.g. for E.V.A. or following a solar particle event, is immediately available. Near-tissue equivalent CR-39 ...

International Nuclear Information System (INIS)

Techniques for reducing computation time in 3D photon dose calculations are addressed with specific emphasis given to the convolution/superposition approach. A single polyenergetic superposition model calculating absorbed dose per incident photon fluence (Gy cm"2) was developed in terms of TERMA and a total energy deposition kernel (a total point spread function). A novel approach was devised for reducing calculation time. The method, named the CF method, was based on the use of a conventional, fast model (here a modified power-law method was used) for the generation of 3D dose distributions on a fine dose matrix. Superposition calculations were carried out on a coarse matrix and calculation speed was increased simply by reducing the number of calculations. A set of correction factors was derived on the coarse grid from the ratio of the dose values from ...

Energy Technology Data Exchange (ETDEWEB)

Epiphyseal plates of growing bones are sensitive to ionizing radiation and this poses problems for the paediatric radiotherapist. In this case report we describe a child in whom electron beam therapy to the groin delivered only low dose radiation to the proximal hip epiphyses - 130 cGy fractionated over 5 weeks - but who suffered late maldevelopment. We explore the success of various radiotherapy techniques in minimizing the dose to the hip epiphyses in four other children. The appropriate positioning of the limb, the choice of treatment modality and, where possible, individual shielding blocks are considered and their effect on the dose to the hip estimated. Absorbed doses of radiation delivered to the midpoint of the proximal femoral epiphyses have been retrospectively determined. (author).

International Nuclear Information System (INIS)

The suitability of calcium silicate bricks (CSBs) for the retrospective measurement of gamma dose using luminescence techniques has been investigated. Bricks of this type are distinguished from fired clay bricks by containing negligible clay and requiring comparatively low temperature treatment during manufacture. They have been used widely in the construction f buildings in the Former Soviet Union since the 1970s but hitherto have not been used for retrospective dosimetry measurements. A procedure based on the se of the 210 deg. C thermoluminescence (TL) peak of quartz was tested with granular quartz extracted from three types of CSB, one of which had been taken from a settlement downwind of Chernobyl. The degree to which the residual geological TL signal within the temperature range of the 210 deg. C L peak had been reduced during manufacture varied with brick type; the levels of residual TL corresponded, in the samples tested, to absorbed ...

Energy Technology Data Exchange (ETDEWEB)

Simulations and experiments have been carried out to explore using a plastic scintillator as a dosimetry probe in the vicinity of a pulsed bremsstrahlung source in the range 4 to 20 MeV. Taking advantage of the tissue-equivalent properties of this detector in conjunction with the use of a fast digital signal processor near real-time dosimetry was shown to be possible. The importance of accounting for a broad energy electron beam in bremsstrahlung production, and photon scattering and build-up, in correctly interpreting dosimetry results at long stand-off distances is highlighted by comparing real world experiments with ideal geometry simulations. Close agreement was found between absorbed energy calculations based upon spectroscopic techniques and calculations based upon signal integration, showing a ratio between 10 MeV absorbed dose to 12 MeV absorbed dose of 0.66 at a distance of ...

Energy Technology Data Exchange (ETDEWEB)

Methylmethacrylate polymerisation in the presence of 4 wt% butadiene-acrylonitrile rubber was carried out at fixed dose-rate and temperature. The effect of irradiation was investigated with respect to the mechanical and dynamic-mechanical properties in the solid state. A general increase of the 'compatibilisation' on irradiation is obtained. In fact both rubber and polymethylmethacrylate glass transition temperatures, determined through dynamic-mechanical analysis, reveal the presence of strong interactions between the components. Furthermore an improvement of the mechanical tensile properties of the blends is observed when irradiation is continued after polymerisation, at least until a certain absorbed dose.

International Nuclear Information System (INIS)

The Monte Carlo transport codes LAHET and MCNP were used to calculate energy fluence spectra at three neutron therapy facilities. The results compare very favourably with measured data. Kerma spectra and the ratio of ICRU muscle tissue kerma to A-150 kerma, along the carbon to oxygen kerma ratio, were determined. Absorbed dose rate calculations are in reasonable agreement with measured values. Use of these codes to study modifications to existing therapy beams is briefly discussed. (author).

Energy Technology Data Exchange (ETDEWEB)

To determine if barbiturates would protect brain at high doses of radiation, survival rates in rats that received whole-brain x-irradiation during pentobarbital- or lidocaine-induced anesthesia were compared with those of control animals that received no medication and of animals anesthetized with ketamine. The animals were shielded so that respiratory and digestive tissues would not be damaged by the radiation. Survival rates in rats that received whole-brain irradiation as a single 7500-rad dose under pentobarbital- or lidocaine-induced anesthesia was increased from between from 0% and 20% to between 45% and 69% over the 40 days of observation compared with the other two groups (p less than 0.007). Ketamine anesthesia provided no protection. There were no notable differential effects upon non-neural tissues, suggesting that pentobarbital afforded protection through modulation of ...

Energy Technology Data Exchange (ETDEWEB)

The performance of a solar chemical heat pipe was studied using CO{sub 2}reforming of methane as the endothermic reaction. A directly heated vertical reactor, packed with a rhodium catalyst was used. The solar tests were carried out in the Schaeffer solar furnace of the Weizmann Institute of Science. The power absorbed was up to 6.3 KW, the maximal flow rates of the gases reached 11,000 1/h, and the methane conversions reached 85%. A computer model was developed to simulate the process. Agreement of the calculations with the experimental results was quite satisfactory.

International Nuclear Information System (INIS)

With accurate calculation algorithms in inverse planning for beamlet-based intensity modulated radiotherapy (IMRT), it takes time to calculate the dose matrix, which represents the dose distribution of each beamlet element to each voxel for unit fluence. To reduce the calculation time, coarse or approximate algorithms are often a choice, but this results in a final dose distribution that cannot reflect the real value. In addition, it is necessary to test if a coarse algorithm is capable of calculating the dose matrix of beamlets. In this work, simulated dynamics optimization algorithm was applied to optimize the segment weight to minish the dose error from the dose matrix calculation. After calculating the dose matrix by ray-tracing algorithm which takes into account just the primary component of absorbed ...

International Nuclear Information System (INIS)

Full - grown pupae of the cotton leaf worm Spodoptera littorals (Boisd.) were gamma - irradiated with low doses of 25,50,75, or 100 Gy for male line and with 50 or 100 Gy for female line . The effects on reproduction, development and sex ratio were the biological aspects studied among P1,F1,F2 and F 3 generations . Also, the effects of dose accumulation applied grown male pupae through two or three filial generations and the retarded influence on their F1,F2,and F 3 progeny were examined. In another trial the histological examinations for ovaries and testes of irradiated parents and for their generation were made . The F1 males were more sterile than irradiated parental males while F1 females were more fertile than their irradiated parental females. Irradiation of P1 males did not clearly affect neither the percentage of mated females nor the average number of spermatophores per mated female among the individuals of P1,F1,F2 and F 3 ...

CERN Document Server

Radiation protection of the personnel who will perform interventions in the LHC Beam Cleaning Insertions is mandatory and includes the design of equipment and the establishment of work procedures. Residual dose rates due to activated equipment are expected to reach significant values such that any maintenance has to be planned and optimized in advance. Three-dimensional maps of dose equivalent rates at different cooling times after operation of the LHC have been calculated with FLUKA. The simulations are based on an explicit calculation of induced radioactivity and of the transport of the radiation from the radioactive decay. The paper summarizes the results for the Beam Cleaning Insertions and discusses the estimation of individual and collective doses received by personnel during critical interventions, such as the exchange of a collimator or the installation of Phase 2. The given examples outline the ...

International Nuclear Information System (INIS)

Following the publication (Stenhouse and Baxter, Nature; 267:828 (1977)) of the levels of bomb "1"4C and the residence times of carbon in the human body, excess radiation burdens from this radioisotope are evaluated under the assumption that no radiation dose, however small, can be regarded as entirely harmless biologically. The estimated annual absorbed dose attributable to "1"4C both natural and man-made for 1953-1973 and similar predicted figures for 1975-2025 are shown graphically. The cumulated doses to gonads (over 30 yr) and to bone marrow and bone-lining cells (over 60 yr) and also estimates of the biological damage to reproductive cells from "1"4C #beta#-irradiation (30 yr accumulated dose) are presented. It is concluded from both genetic and somatic considerations, that the potential human radiation burden due to artificially produced "1"4C calculated using the assumptions ...

International Nuclear Information System (INIS)

The risks from mining and processing of ores is reviewed on a generic basis with particular reference to some of the confusions which can arise due to lack of consistency or common logic in the use of exclusion, exemption and clearance. The difference in exclusion and exemption are challenged by comparing doses received in high background radiation areas and the doses received from a mining practice. The common principle of risk to the human species is not applied consistently. The differences between IAEA recommendations and local regulatory conditions are compared, and the use of exemption levels as clearance levels is considered. A case study on management of mine tailings is presented with special focus on the use of clearance levels. In all areas of review the interpretation of regulation is subject to confusion resulting from inconsistencies which can distort free market economics. (author).

Energy Technology Data Exchange (ETDEWEB)

Faced with increasing indications for the use of iodine-131 labelled lipiodol in the treatment of hepatocellular carcinoma (HCC), it appears essential to develop an individualized dosimetrY so we can predict the potential effectiveness of this treatment and adjust the activity to be injected. We developed a dosimetric protocol based on imagery and dedicated to calculation of the tumoral dose during the treatment of hepatocellular carcinoma by iodine-131 labelled lipiodol. This concept was developed on a SPECT- CT gantry, and integrates corrections for the phenomena of attenuation, diffusion and dead time. The dose is calculated according to the formalism proposed by the Medical Internal Radiation Dose Committee (MIRD). This protocol was applied to a series of 41 patients in the framework of a retrospective study. The results obtained in terms of biodistribution are compatible with previously published data. The total ...

International Nuclear Information System (INIS)

The 9.50 GHz electron paramagnetic resonance (EPR) spectra of unirradiated and "6"0Co #gamma#-ray irradiated cardamom (Elettaria cardamomum L. Maton, Zingiberaceae), ginger ((Zingiber officinale Rosc., Zingiberaceae), and saffron (Crocus sativus L., Iridaceae) have been investigated at room temperature. All unirradiated spices presented a weak resonance line with g-factors around free-electron ones. After #gamma#-ray irradiation at an absorbed dose of up to 11.3 kGy, the presence of EPR spectra whose amplitude increase monotonously with the absorbed dose has been noticed with all spices. A 100 "oC isothermal annealing of 11.3 kGy irradiated samples has shown a differential reduction of amplitude of various components that compose initial spectra, but even after 3.6 h of thermal treatment, the remaining amplitude represents no less then 30% of the initial ones. The same peculiarities have been noticed ...

Energy Technology Data Exchange (ETDEWEB)

In order to calculate the doses received by the organs of 530 children treated by radiation for cancer between 1945 and 1969 at the G. Roussy Institute, we have developed a computer program for organ location calculation. To calculate the location of each child's organs of interest at the time of the treatment, only two parameters are necessary; sex and height or sex and age when the height at the time of the treatment is unknown. The algorithm is based on the metric studies of growth known as auxology. Each organ is located by one point representing its center. The model has been checked on 100 healthy children.

Energy Technology Data Exchange (ETDEWEB)

Gel dosimetry is a new dosimetry method applied in radiation therapy. Gel dosimeters consist of a radiation sensitive gel, which can integrate absorbed doses from several radiation sources or beams. The dose to the gel can be evaluated by magnetic resonance imaging (MRI), a procedure that is the focus of the present thesis. A robust tool for the evaluation of the nonuniformity in MRI has been developed, the Deviation Image method. Unlike previously presented methods, the Deviation Image method includes all nonuniformity variations across a phantom surface and is insensitive to stochastic noise. Methods for the estimation of stochastic noise were analyzed in terms of sensitivity to nonuniformities. A method that averages the stochastic noise level over five regions over the phantom surface, and a method that assesses the stochastic noise level from the background, were found to be the methods of choice. Pronounced MR image ...

International Nuclear Information System (INIS)

The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and careful caudal shielding of the field are ...

British Library Electronic Table of Contents (United Kingdom)

Purpose To study the chemical modifications induced upon irradiation of solid human insulin at radiosterilization doses and investigate the influence of the absorbed dose on radiolysis. Materials and Methods Volatile radiolytic products were monitored by gas chromatography coupled with mass spectrometry (GC-MS) and non-volatile products by two different high performance liquid chromatography (HPLC) methods: the formation of higher molecular weight proteins was assessed by size exclusion liquid chromatography whereas assays for related compounds and chemical potency tests were carried out using reverse-phase HPLC-UV. Conformational changes were investigated by measurements of circular dichroism. Results After gamma irradiation at 10?kGy, the recovery of insulin was 96.8%; higher molecular w...

Energy Technology Data Exchange (ETDEWEB)

Although it has been established that lead is transferred in milk from mother to suckling offspring, the physiological processes and parameters involved are not well understood. Single i.v. doses (0.2 mg/kg) or p.o. doses (2 mg/kg) of radiolabeled lead were administered to lactating and nonlactating female mice, and lead concentrations in blood, plasma, and milk were determined during a 21-day period. Large differences in lead elimination were observed between lactating and nonlactation mice. A significant fraction (25%) of the initial maternal dose (absorbed dose) was transferred to the suckling pups. The ratio of lead concentration in milk to lead concentration in plasma was found to be nearly constant over time. However, the milk-to-blood concentration ratios decreased during the same period. Furthermore, the concentration of lead in milk exceeded the plasma concentration by a ...

International Nuclear Information System (INIS)

Recent research findings of epidemiologist Alice Stewart suggest that nuclear workers may be at risk of contracting cancer even though their measured occupational doses fall within current safety standards. It is argued that these standards are inappropriate as they are based on extrapolations of studies on survivors of the Hiroshima and Nagasaki explosions. These individuals received single doses of radiation, whereas today's nuclear industry personnel are exposed to low-level ionizing radiation over the length of their working lives. Stewart's team linked low dose occupational exposure to ionizing radiation with an increased risk of cancer in respiratory, digestive and blood-forming tissues. The nuclear industry and United States government agencies hotly contest these assertion with their potentially damaging political and economic consequences. (UK).

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Subcutaneous involvement frequently occurs in maxillary sinus carcinoma. Radical resection does not include removal of the skin at risk. In standard postoperative wedge-pair treatment plans, the surface dose is dependent upon beam weighting, beam energy, and patient contour. Thermoluminescent dosimetry (TLD) measurements were performed to evaluate the surface dose of patients undergoing postoperative irradiation of maxillary sinus carcinoma following primary resection. When 60 Gy was delivered to isocenter with a 45 degrees wedge pair and 6 MV photons with 1 cm bolus, the subcutaneous tissues at risk received {approximately} 30 Gy. Based upon presented TLD measurements, supplemental electron beam therapy to the subcutaneous tissues if primarily involved should be considered.

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A number of diagnostic X-ray units in Poland were subjected to analysis. The air kerma on X-ray tables was measured for the X-ray parameters used routinely during lumbo-sacral spine radiography of standard adult patient. Measurements of air kerma were performed using TLD made of lithium-fluoride. The doses received by patients in different X-ray departments can differ more than two orders of magnitude (from 0.42 mGy up to 72.11 mGy), for the same X-ray examination. The dose can be significantly reduced if fluorescent screens made from components of rare earth are used. (author). 10 refs, 1 fig., 2 tabs.

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Radiation protection programs for workers are based, in the United States, on a hierarchy of limitations stemming from Federal guidance approved by the President. This guidance, which consists of principles, policies, and numerical primary guides, is used by Federal agencies as the basis for developing and implementing their own regulatory standards. The primary guides are usually expressed in terms of limiting doses to workers. The protection of workers against taking radioactive materials into the body, however, is accomplished largely through the use of regulations based on derived guides expressed in terms of quantities or concentrations of radionuclides. The values of these derived guides are chosen so as to assure that workers in work environments that conform to them are unlikely to receive radiation doses that exceed the primary guides. The purpose of the present report is to set forth derived guides that are ...

International Nuclear Information System (INIS)

Rectum reference dose points have a direct impact on the morbidity seen in gynecological intracavitaty radiotherapy. The aim of this study is to obtain less morbidity by marking rectum with radio opaque solution. Fourteen patients with gynecological cancer who underwent external radiotherapy received 15 Gray (Gy) intracavitary radiotherapy. During the internal radiotherapy planning, radio opaque solution has been administered into the rectum to observe it on lateral radiogram. Thus rectum reference dose point and five points were marked at sites nearest to the sources. Nucletron Planning system was used for obtaining three-dimensional planning. After therapy patients were followed at every three months. Median follow-up was 18 months. Most frequently observed morbidities were grade 1-2 rectitis and cystitis in six patients. As a result, more accurate rectum dose values and less factors causing ...

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Ovarian function was evaluated in 11 women 16 to 43 years of age at treatment who received doxorubicin, cyclophosphamide, and high doses of methotrexate with or without radiotherapy in adjuvant therapy of soft tissue sarcoma. Five women (16-33 yr old) who received chemotherapy alone or combined with radiotherapy only at sites distant from the ovaries (chest wall, thigh, and leg) had minimal menstrual irregularities or temporary cessation of menses during therapy; cyclic menses returned promptly after therapy. Gonadotropin levels (expressed as means +/- SD) (follicle-stimulating hormone (FSH), 10 +/- 15 mlU/ml; luteinizing hormone (LH), 10 +/- 4 mlU/ml) and 17 ..beta..-estradiol (E/sub 2/) levels (means +/- SD, 208 +/- 147 pg/ml) were normal. By contrast, 4 older women (ages 36-43 yr) who received similar treatment developd persistent amenorrhea with postmenopausal levels of gonadotropin (FSH, 109 +/- 29 ...

International Nuclear Information System (INIS)

Purpose: A retrospective analysis was undertaken to determine the indications for, the efficacy of, and the long-term complications of two courses of total skin electron beam therapy for mycosis fungoides. Methods and Materials: A retrospective analysis of 15 patients with the pathologic diagnosis of mycosis fungoides treated in the Department of Radiation Oncology at Stanford University Medical Center between 1968 and 1990 was performed. All patients received two courses of high-dose electron beam therapy to the skin. The mean dose for the total skin treatment for the first course was 32.6 Gy and 23.4 Gy for the second course of treatment. Results: Following the first course of total skin electron beam therapy, 11 of 15 had a complete response, with a mean duration of 11.6 months. All patients received adjuvant therapies between the first and second courses of high-dose total skin ...

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This study evaluates the effect of gamma radiation on the viability of fungi and actinomycetes that contaminate medicinal plants. The relationship between the total lipids of some fungi and actinomycetes and their sensitivity to gamma radiation is also investigated. The data reveal that the viable counts of these florae decrease approximately exponentially with the radiation dose, the effective dose for the elimination of these microorganisms being about 5 kGy for all the medicinal plants under study. Response of pure cultures of fungi and actinomycetes isolated from medicinal plants to increasing absorbed doses of gamma radiation indicate that an increase in radioresistance is in the following order: Streptomyces rimosus, Fusarium solani, Nocardia kuroishii. F. oxysporum, A. fumigatus, A. flavus, A. parasiticus and A. ochraceus. The total lipid contents of molds and actinomycetes have been reported to ...

KoreaScience (Korea)

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Solar ultraviolet radiation is damaging for living organisms due to its high energy pro each photon. The UV radiation is often separated into three regions according to the wavelength: UVC (200-280 nm), UVB (280-320 nm) and UVA (320-400 nm). The most hazardous part, UVC is absorbed completely in the upper atmosphere by molecular oxygen. UVB radiation is absorbed by atmospheric ozone partly, and it is reaching Earth`s surface, as UVA radiation. Besides atmospheric ozone, very important factors in determining the intensity of UVB radiation globally are the solar zenith angle and cloudiness. It may be calculated from global ozone changes that the clear-sky UVB doses may have enhanced by 10-15 % during spring and 5-10 % during summer at the latitudes of Finland, following the decrease of total ozone between 1979-90. The Finnish ozone and UV monitoring activities have become a part of international activities, especially the EU ...

International Nuclear Information System (INIS)

Magnetic particles (MAG*SEP"S"M) coated with various absorbents were evaluated for the separation and recovery of low concentrations of cesium from nuclear waste solutions. The MAG*SEP"S"M particles were coated with (1) clinoptilolite, (2) transylvanian volcanic tuff, (3) resorcinol formaldehyde, and (4) crystalline silico-titanate, and then were contacted with a Hanford supernatant simulant. Particles coated with the crystalline silico-titanate were identified by Bradtec as having the highest capacity for cesium removal under the conditions tested (variation of pH, ionic strength, cesium concentration, and absorbent/solution ratio). The MAG*SEP"S"M particles coated with resorcinol formaldehyde had high distribution ratios values and could also be used to remove cesium from Hanford supernant simulant. Gamma irradiation studies were performed on the MAG*SEP"S"M particles with a gamma dose equivalent to 100 cycles of use. ...

International Nuclear Information System (INIS)

Full text: Optically stimulated luminescence (OSL) dating of individual sand-sized grains of quartz has advanced significantly over the past decade opening up new vistas in luminescence geochronology. Today, single-grain OSL dating can be used to constrain the burial ages of many deposits, including fluvial sediments, glaciofluvial material and archaeological sediments. It also provides a means of examining the stratigraphic integrity of archaeological sites where sediment mixing might have occurred. An OSL age is calculated by dividing the burial dose (the dose absorbed by the grain since it was last exposed to sunlight) by the environmental dose rate (the rate of supply of ionizing radiation to the grain over the period of burial). To obtain reliable OSL ages, therefore, an accurate estimate of the dose rate is required for each sample. Here we describe our OSL dating campaign at ...

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The use of hypothesis which assumes a dose / harmful effect relationship without a limit allows the calculation of risks attributable to doses too small to produce detectable, harmful biological effects. The daughter product of this hypothesis is ALARA concept which requires that the dose received is kept as low as reasonably achievable. This concept of prudent avoidance is generally accepted by international radiation protection organisations and universally applied by radiation health professionals. The acceptance of a hypothesis which assumes that a single nuclear event can cause carcinogenesis, has generated levels of anxiety which may have resulted in significant detriment to those possibly exposed to ionising radiation. The anxiety generated may have caused more detriment and a higher death rate than the worst case ` theoretical` value calculated using the Linear or Quadratic Linear Hypothesis. ...

International Nuclear Information System (INIS)

Background and purpose: the recent RTOG guidelines for future clinical developments in gynecologic malignancies included the investigation of dose escalation in the paraaortic (PO) region which is, however, very difficult to target due to the presence of critical organs such as kidneys, liver, spinal cord, and digestive structures. The aim of this study was to investigate intensity-modulated radiotherapy's (IMRT) possibilities of either increasing, in a safe way, the dose to 50-60 Gy in case of macroscopic disease or decreasing the dose to organs at risk (OR) when treatment is given in an adjuvant setting. Material and methods: the dosimetric charts of 14 patients irradiated to the PO region at the department of radiation oncology, university hospital of Liege, Belgium, in 2000 were analyzed in order to compare six-field conformal external-beam radio-therapy (CEBR) and five-beam IMRT approaches. Both CEBR and IMRT ...

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In the Harghita volcanic range (Romania) there are many occurrences of dry CO{sub 2} emanations, called mofettes. The emanating gas with high carbon dioxide content has a proved curative effect. The gas also contains important quantities of radon. Since the mofettes are used in curative purposes in several illnesses, in most of the cases without medical supervising, has been proposed to determine the radon activity concentration in some of the most frequented mofettes from Romania. The seasonal variations have also been monitored and were calculated the effective doses received by the patients during a cure. The radon activity concentrations' levels above the mofettes indoor air range between 548 and 10 717 Bq/m{sup 3} while within the gas pools' values between 3210 and 32 781 Bq/m{sup 3} have been measured. The effective dose received by the patients during a cure is between 0.0086 ...

International Nuclear Information System (INIS)

We report the radiation exposure dose received by the anesthesiologist and nurse in the orthopaedic operating room, when a fluoroscopic image intensifier is in use. This study was done in 12 femoral neck fracture operations performed from January to May 1995. Radiation was monitored with the MYDOSE MINIX PDM 107 made by Aloka Co. which were attached in front and behind the nurse's lead apron, in front of the lead apron of the anesthesiologist. The average imaging time was 9.78 min. The average radiation dose in front of the anesthesiologist is lead apron was 2.08#mu#SV, and in front and behind the nurse's lead apron were 5.67#mu#SV, 0.08#mu#SV respectively. This study and review of the literature indicate that the operating room anesthesiologist and nurse receive a lower exposure than the orthopaedist. We can disregard the problem of radiation exposure to the anesthesiologist and nurse during an ...

International Nuclear Information System (INIS)

The primary UK legislation relating to the use of radioactive materials are the Radioactive Substances Act 1993 (RSA, 1993) and the Ionising Radiations Regulations 1999 (IRR, 1999). These implement the European Union's Basic Safety Standards Directive (EUBSS) (EC, 1996). The Radioactive Substances Act 1993 (RSA93) regulates the accumulation, storage and disposal of radioactive waste, principally to control potential doses to members of the public. The Ionising Radiations Regulations 1999 (IRR, 1999) deal primarily with regulating the doses that people receive at work. Both of these pieces of legislation apply to the use of materials containing naturally occurring radionuclides. Historically UK regulations relating to radioactive materials have covered both artificial and natural radionuclides

International Nuclear Information System (INIS)

Using high-resolution y-rays spectrometry, the natural radioactivity of 14 samples of natural and o manufactured Egyptian building materials have been investigated. The samples were collected from local market and construction sites. From the measured gamma-ray spectra, specific activities were determined. The radium equivalent activity in each sample was estimated. Radiological evaluations of these materials indicate that all materials meet the external gamma-ray dose limitation. Calculation of concentration indices by assuming a Markkanen room model is constructed from these materials, to find the excess gamma-ray dose taken over that received from the outdoors. The Austrian Standard ONORM S 5200 is used in testing the building materials.

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Experiments were designed to elucidate whether or not the irradiated bone marrow cells receive any stimulation for the self-replication and differentiation from normal 'stromal' cell colonies in the bone marrow cell culture in vitro. When irradiated or unirradiated bone marrow cells were overlaid on the normal adherent cell colonies, the proliferation of haemopoietic stem cells was supported, the degree of the stimulation depending on the starting cellular concentration. There was, however, no significant changes in the concentration of either CFUs or CFUc regardless of the dose of irradiation on the bone marrow cells overlaid. This was a great contrast to the dose-dependent decrease of CFUs or CFUc within the culture in which both the stem cells and stromal cells were simultaneously irradiated. These results suggest that the balance of self-replication and differentiation of the haemopoietic stem cells is ...

British Library Electronic Table of Contents (United Kingdom)

Magnesium fructose-1,6-diphosphate is a novel agent of antimyocardial ischaemia. In the present study, the subchronic toxicity of magnesium fructose-1,6-diphosphate was investigated after 13-week repeated intravenous administration in beagle dogs. The animals received doses of 0, 75, 150 and 300 mg/kg/day (three males and three females for each dose). During the study period, clinical signs, mortality, body weights, food consumption, electrocardiogram, urinalysis, haematology, clinical biochemistry, macroscopic findings, organ weights and histopathology were examined. The administration of magnesium fructose-1,6-diphosphate resulted in increased incidence of clinical signs, including salivation and emesis. These effects were transient and were noted in almost all dogs given 300 mg/kg/day a...

International Nuclear Information System (INIS)

New values of the factors required to convert the reading of a radiation dosemeter calibrated in terms of air kerma (or exposure) into absorbed dose to water for medium-energy x-radiation were given in a code of practice published by the International Atomic Energy Agency in 1987. These are not considered to possess sufficient support from other sources. It is therefore recommended that the F-factors given or codes of practice should continue to be used. Values of backscatter factors for low-energy x-radiation (below 140 kV) in Supplement 17 of the British Journal of Radiology appear to be inaccurate. New values based on Monte Carlo calculations, and supported by new experimental data, are given for use in radiotherapy. (author).

International Nuclear Information System (INIS)

The radiation induced reactions in LDPE in the presence of phenolic type antioxidants have been studied. It was shown that various antioxidants can influence the polyethylene network formation and the radical yield in different ways. The dependence of network structure on absorbed doses was determined by gel analysis, hot-set test and extraction of antioxidants for samples irradiated with accelerated electrons. It was found that the antioxidants eluted from polyethylene in higher percentage influence polymer crosslinking to a smaller degree. The ESR studies of #gamma#-irradiated blends of polyethylene with antioxidant indicate the presence of alkyl and phenoxyl radicals. The role of antioxidant molecules on radiation induced reactions in polyethylene-antioxidant systems is considered. The correlation between the network structure and the type of additive in polyethylene is also discussed. (author).

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The purpose of this work was to determine the radiolytic hydrogen gas yield of irradiated CSSX solvent at several temperatures. The active ingredient of this solvent is calix[4]arene-bis-(t-octylbenzo) crown-6, a calixarene crown ether used for cesium complexation. The solvent also contains 1-(2,2,3,3-tetrafluoropropoxy)-3-(4-sec-butylphenoxy)-2-propanol, a fluorinated alcoholic solvent modifer used to improve the solubility of the calixarene and its cesium complex in the Isopar L diluent. Isopar L is a branch-chain alkane and comprises most of the mixture. Samples of this solution were irradiated to various absorbed ?-ray doses in gas-tight sample containers, which were then sampled for hydrogen gas content. The methods are described below.

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Procedures for {sup 131}I ablation in renal failure are not known. In one patient receiving dialysis, detailed dosimetry and health safety aspects were obtained. The results showed insignificant contamination of equipment, but a surprisingly significant reduction in biologic half-life of {sup 131}I due to efficient dialysis extraction. The data indicate that {sup 131}I ablation can be done safely and easily during dialysis but that much higher {sup 131}I doses must be used to achieve equivalent results to those obtained in patients with normal renal function.

International Nuclear Information System (INIS)

Background: In the German CESS-studies, Ewing's sarcoma patients with pulmonary metastases at diagnosis were considered as candidates for additional bilateral lung irradiation. We have retrospectively analyzed the impact of radiotherapy on survival. Material and methods: Out of 42 patients presenting with pulmonary metastases of Ewing's sarcoma between 1981 and June 1992, 30 were evaluable. One patient died of progressive disease prior to lung irradiation. The other patients had a complete radiographic remission either after chemotherapy (n=25) or chemotherapy plus resection of lung metastases (n=4). 22 patients received bilateral lung irradiation with doses of 12 to 21 Gy (once daily 1.5 Gy or twice daily 1.25 Gy), six had no further treatment and one had bone marrow transplantation for consolidation. Results: Ten patients are in complete remission, nine of them had received lung irradiation and one had a complete ...

International Nuclear Information System (INIS)

Values of the chemical yield, G, and of the molar extinction coefficient, epsilon, for Fricke dosimetry, have been recommended by ICRU. For epsilon, the value in ICRU Reports 17 and 21, 2205 1.mol"-"1.cm"-"1, based on an analysis of 83 reported values. It was suggested that, where neither a careful wavelength calibration nor absorbance linearity checks had been performed, a standard error of 1.5% should be assumed; otherwise 0.15% could be accepted. Alternatively, the accuracy in applying this chemical dose meter was considered improved if there was an independent determination of epsilon with the same spectrophotometer as was used for the determination of the optical density of irradiated Fricke solution. The accuracy claimed for both methods remains questionable, since no complete argumentation could be given for the differences of up to 13% in the published values. Taking into account the discussion of the sources of error by Bryant, ...

International Nuclear Information System (INIS)

Thermoluminescence (TL) and Electron Paramagnetic Resonance (EPR) dosimetry were used to measure dose effects in borosilicate glass with time, from 10 minutes to #approx#60 days following exposure to a dose of up to 10,000 Rad. TL and EPR results were consistent and performed similarly, with both techniques capable of achieving an estimated limit of detection of between 50-100 Rad. Three peaks were identified in the TL glow curve at roughly 110 C, 205 C, and 225 C. The intensity of the 205 C peak was the dominant peak over the time period of this study. The stability of all of the peaks with time since irradiation increased with their corresponding temperature and little or no variation was observed in the glow curve response to a specified total dose attained at different dose rates. The intensity of the 205 C peak decreased logarithmically with time regardless of total dose. Based ...

International Nuclear Information System (INIS)

Purpose: To evaluate the effect of low-dose radiation therapy and surgery on local control in patients with Ewing's Sarcoma. Materials and Methods: Between 1979 and 1995 24 patients (ages 4-47) with Ewing's sarcoma were treated with combined modality therapy that included multi agent chemotherapy, surgical resection, and radiation therapy. Twelve patients had metastatic disease at the time of presentation (pleura = 3, lung = 5, bone 4). Tumor location was central in 16 and peripheral in 8. Multi agent chemotherapy consisted of vincristine/actinomycin D/cyclophosphamide/doxorubicin in 19. The same agents with the addition of ifosfamide and etoposide were given in 5. The extent of resection was considered to be radical in 14 and of the 16 patients who received preoperative chemotherapy, 5 were found to have a pathologic complete response. All patients with lung metastases at diagnosis received whole-lung irradiation to 1400 ...

International Nuclear Information System (INIS)

Processing of food with ionizing radiation is a method suitable to enhance shelf-life and hygienic quality. Up to a dose of 10 kGy the method is considered wholesome. In many countries the practical use of food irradiation is increasing, however, in the Federal Republic of Germany the process is strictly forbidden. Applications and methods for radiation processing of food are compiled, limits and prospects are explained, and advantages and disadvantages are compared with traditional methods. Identification of irradiated foods and dosimetry and process control for radiation processing of food are areas where further research is needed. Continuous processing of particulate foods in bulk is an application where electron accelerators might be profitable. Beam parameters and velocity distribution of food particles in the treatment area can be matched for an effective result. Thus, dose distribution can be adjusted for homogeneous treatment and at ...

International Nuclear Information System (INIS)

The accuracy of dose computation within the lungs depends strongly on the performance of the calculation algorithm in regions of electronic disequilibrium that arise near tissue inhomogeneities with large density variations. There is a lack of data evaluating the performance of highly developed analytical dose calculation algorithms compared to Monte Carlo computations in a clinical setting. We compared full Monte Carlo calculations (performed by our Monte Carlo dose engine MCDE) with two different commercial convolution/superposition (CS) implementations (Pinnacle-CS and Helax-TMS's collapsed cone model Helax-CC) and one pencil beam algorithm (Helax-TMS's pencil beam model Helax-PB) for 10 intensity modulated radiation therapy (IMRT) lung cancer patients. Treatment plans were created for two photon beam qualities (6 and 18 MV). For each dose calculation algorithm, patient, and beam quality, the ...

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Non-uniform radionuclide distribution in tumours will lead to a non-uniform absorbed dose. The aim of this study was to investigate how tumour control probability (TCP) depends on the radionuclide distribution in the tumour, both macroscopically and at the subcellular level. The absorbed dose in the cell nuclei of tumours was calculated for {sup 90}Y, {sup 177}Lu, {sup 103m}Rh and {sup 211}At. The radionuclides were uniformly distributed within the subcellular compartment and they were uniformly, normally or log-normally distributed among the cells in the tumour. When all cells contain the same amount of activity, the cumulated activities required for TCP = 0.99 (A-tilde{sub TCP=0.99}) were 1.5-2 and 2-3 times higher when the activity was distributed on the cell membrane compared to in the cell nucleus for {sup 103m}Rh and {sup 211}At, respectively. TCP for {sup 90}Y was not affected by different ...

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In an effort to evaluate the feasibility of introducing computed radiography (FCR) into mass screening for lung cancer, the ability of FCR to detect nodules one cm in diameter was examined using a humanoid chest phantom. Based on the receiver operating characteristic (ROC) analysis, the detectability of FCR was compared with that of conventional radiography and photofluorography. The values of area under ROC curves were higher for FCR (0.963 for image similar to that with conventional film-intensifying screen system, image A; and 0.952 for processed image, image B) than the other two methods (0.774 for radiography and 0.789 for photofluorography). Degradation of image quality in FCR could be avoided by a wide latitude even if proper exposure techniques might not be employed. Images A and B in FCR yielded excellent delineation for nodules in the lung field and in the retrocardiac and subdiaphragmatic regions, respectively. This may have implications for the value of ...

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An approximate solution was proposed in which a sensitivity analysis by the storage and release of heat was performed for the subject issues and in which an operating method was thereby determined for the equipment constituting the system by means of a linear programming. Accordingly, a heat storage type energy supply system for a district cooling and heating was taken up as a concrete object to be examined. This system consisted of a gas turbine generator, initial power receiving equipment, gas boiler, electric heat pump for ice heat storage, cooling tower, heat exchanger, steam absorbing refrigerating machine, ice heat storage tank, cold and warm water heat storage tank, etc. As a result of comparison between the proposed method and the resolving method, the former showed -0.92 to 2.58% in the increase in the operating cost compared with the latter. A case where the operating cost of the resolving method was sometimes larger than the proposed ...

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ITN Energy Systems is developing next-generation solar cells based on the concepts of an optical rectenna. ITN's optical rectenna consists of two key elements: (1) an optical antenna to efficiently absorb the incident solar radiation, and (2) a high-frequency metal-insulator-metal (MIM) tunneling diode that rectifies the AC field across the antenna, providing DC power to an external load. The combination of a rectifying diode at the feedpoints of a receiving antenna is often referred to as a rectenna. Rectennas were originally proposed in the 1960s for power transmission by radio waves for remote powering of aircraft for surveillance or communications platforms. Conversion efficiencies greater than 85% have been demonstrated at radio frequencies (efficiency defined as DC power generated divided by RF power incident on the device). Later, concepts were proposed to extend the rectennas into the IR and optical region of the ...

British Library Electronic Table of Contents (United Kingdom)

This study addresses the solar thermal decomposition of natural gas for the co-production of hydrogen and carbon black (CB) as a high-value nano-material with the bonus of zero CO2 emission. The work focused on the development of a medium-scale solar reactor (10kW) based on the indirect heating concept. The solar reactor is composed of a cubic cavity receiver (20cm-side), which absorbs concentrated solar irradiation through a quartz window by a 9cm-diameter aperture. The reacting gas flows inside four graphite tubular reaction zones that are settled vertically inside the cavity. Experimental results in the temperature range 1740-2070K are presented: acetylene (C2H2) was the most important by-product with a mole fraction of up to about 7%, depending on the gas residence time. C2H2 content i...

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In this work dosimetric analysis using thermoluminescence technique to study the beams characteristics of x-rays employed in dental radiology has been carried out. The obtained results with CaSO{sub 4}:Dy thermoluminescent dosimeters (TLD) were compared to the doses obtained with parallel-plates ionization chamber. Dosimetric evaluations were also done using radiographic films of large dimensions. The x-rays equipments analyzed were installed in the radiological services of Odontology Department of Sergipe Federal University (U.F.S.). Depending on the anatomical region to be examined the proper exposure time was select, for a fix voltage of 70 kV. The results with TLD and ionization chamber have been determined to female and male individuals. The intraoral regions analysed were the peri apical of the incisors, molar and pre-molar teeth and the occlusive region. These regions were simulated using acrylic plates absorbers installed on the film ...

International Nuclear Information System (INIS)

Purpose: To evaluate the outcomes of patients with Ewing's sarcoma family of tumors (ESFT) treated with modern radiotherapy techniques with MRI along with optimal chemotherapy. Methods and Materials: The records of all 60 patients with ESFT who received radiation to the primary site between 1990 and 2004 were reviewed. All patients received chemotherapy, including vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide. Radiation was used as the sole modality for local control in 31 patients and was given either before (n = 3) or after surgical resection (n = 26) in the remainder. All patients had MRI and CT scan-based treatment planning, and 43% received intensity-modulated radiation therapy. Radiation doses ranged from 30 Gy to 60 Gy (median, 51 Gy), and 35% received hyperfractionated radiotherapy. Results: Median age was 16 years (range, 2-40 years). Because of ...

International Nuclear Information System (INIS)

Between 1984 and 1988, seven women with breast cancer were treated with intraoperative electron beam therapy (IOEBT). All patients were Caucasian. Patient age ranged from 37 to 62 (median 53) years. Histopathology was infiltrating duct carcinoma (6/7) or medullary carcinoma (1/7). Four tumors were staged T1 N0 MO, one T1 N1 MO, one T2 N1 MO, and one lesion was recurrent. At the time of primary lumpectomy or axillary node dissection, a dose of 10 or 15 Gy IOEBT was administered to the tumor bed with 6 or 9 MeV electrons through the lumpectomy wound. All patients received 45 or 50 Gy over five to six weeks with 6 MV photons to the breast and, in four patients, to the regional nodes. Three patients received adjuvant chemotherapy and tamoxifen. No post-operative complications were observed. All patients are alive as of August, 1989, with no evidence of recurrent disease. Excellent cosmesis is the rule. Clinical and technical ...

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In August 1982, a 44-year-old man was diagnosed as having rectal cancer, histologically diagnosed as well differentiated adenocarcinoma, and abdominoperineal resection and colostomy were performed. Postoperatively, he received chemotherapy with mitomycin C up to a total dose of 100 mg. In September 1986, lung metastasis occurred and he was treated with a combination chemotherapy consisting of cisplatin, pirarubicin and 5-fluorouracil. In the following year, radiation treatment (total: 6900 rad) was given for a recurrent pelvic lesion. Peripheral blood on April 30, 1988, showed anemia, thrombocytopenia and appearance of myeloblasts, and a diagnosis of acute myelogenous leukemia (FAB: M1) was made. Combination chemotherapy (including aclarubicin, vincristine, behenoyl ara-C, daunorubicin, 6-mercaptopurine, cytarabine, etoposide and prednisolone) failed to induce remission and the patient died in June 1988. This case was thought to be one of ...

International Nuclear Information System (INIS)

Purpose: Radiotherapy (RT) has been the predominant local treatment for Ewing's sarcoma of bone at the University of Florida. Twice-daily hyperfractionated RT was initiated in 1982 to improve local control and functional outcome. This retrospective review compares the results of once-daily vs. twice-daily RT in patients with primary Ewing's sarcoma of an extremity, with emphasis on functional outcome. Methods and Materials: Between June 1971 and January 1990, 37 patients were treated at the University of Florida for nonmetastatic Ewing's sarcoma of bone with a primary lesion in an extremity. Three patients underwent amputation. Of 34 patients treated with RT, 31 had RT alone and 3 had a combination of RT and local excision. Before 1982, 14 patients received once-daily RT; since 1982, 17 patients have received twice-daily RT. Doses of once-daily RT varied from 47 to 61 Gy at 1.8-2 Gy per fraction. Doses ...

British Library Electronic Table of Contents (United Kingdom)

Testosterone influences various aspects of affective behavior, which is mediated by different brain regions within the emotion circuitry. Previous neuroimaging studies have demonstrated that testosterone increases neural activity in the amygdala. To investigate whether this could be due to altered regulation of amygdala functioning which is thought to be mediated by the prefrontal cortex, we studied the effects of exogenous testosterone on the interaction between the amygdala and other brain regions. Healthy middle-aged women received a single nasal testosterone dose in a randomized, placebo-controlled, crossover manner, and performed an emotional face matching task while their brain activity was measured with functional MRI. The results show that testosterone rapidly reduced functional co...

International Nuclear Information System (INIS)

The term 'health/functional food' (HFF) refers to food supplements containing nutrients or other substances (in a concentrated form) that have a nutritional or physiological effect whose purpose is to supplement the normal diet. The Korean Health/Functional Food Act that came into effect in 2004 requires these products to be marketed in measured doses, such as in pills, tablets, capsules, and liquids. HFFs are of two types: generic and product-specific. There are 37 ingredients listed in the act for generic HFFs, and if an HFF contains a new active ingredient that is not included in the generic 37 products, it is considered a product-specific HFF. The standardization, safety, and efficacy of a new active ingredient are reviewed by the Korean Food and Drug Administration in order to receive approval as a product-specific HFF. Conforming with international standards and protecting public health requires constant upgrading of the Health/Functional ...

British Library Electronic Table of Contents (United Kingdom)

Summary Background There is a need for new artemisinin-based combination therapies that are convenient, effective, and safe. We compared the efficacy and safety of pyronaridine-artesunate with that of artemether-lumefantrine for treatment of uncomplicated P falciparum malaria. Methods This phase 3, parallel-group, double-blind, randomised, non-inferiority trial was undertaken in seven sites in Africa and three sites in southeast Asia. In a double-dummy design, patients aged 3-60 years with uncomplicated P falciparum malaria were randomly assigned in a 2:1 ratio to receive pyronaridine-artesunate once a day or artemether-lumefantrine twice a day, orally for 3 days, plus respective placebo. Randomisation was done by computer-generated randomisation sequence in blocks of nine by study centre....

Energy Technology Data Exchange (ETDEWEB)

Molybdenum is an essential element for living organisms. Moreover its radionuclides may represent an incorporation risk for members of the public and/or radiation workers after a nuclear accident or a release of radioactive materials. However, only few reliable data on Mo biokinetics in humans were available. The results of recent tracer kinetic investigations with stable isotopes have shown several differences from the ICRP data with regard to the processes of intestinal absorption and of excretion. As a consequence, the dose coefficients calculated with a revised biokinetic model deviate from the ICRP estimates. By ingestion of {sup 99}Mo radionuclides with solid food, for example, the dose to the colon may be higher of a factor up to 1 order of magnitude, due to the fraction of non-absorbed material which traverses the gastro-intestinal tract. (orig.) [Deutsch] Molybdaen ist einerseits ein fuer Lebewesen essentielles ...

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Hepatocellular carcinoma (HCC) is the most common primary liver cancer and has very limited therapeutic options. Recently, it has been found that hyaluronic acid (HA) shows selective binding to CD44 receptors expressed in most cancer histotypes. Since the trend in cancer treatment is the use of targeted radionuclide therapy, the aim of this research was to label HA with rhenium-188 and to evaluate its potential use as a hepatocarcinoma therapeutic radiopharmaceutical. Methods: {sup 188}Re-HA was prepared by a direct labelling method to produce a ReO(O-COO){sub 2}-type coordination complex. {sup 188}Re-HA protein binding and its stability in saline, phosphate buffer, human serum and cysteine solutions were determined. Biokinetic and dosimetric data were estimated in healthy mice (n=60) using the Medical Internal Radiation Dose methodology and mouse model beta-absorbed fractions. To evaluate liver toxicity, alanine aminotranferase (AST) and ...

KoreaScience (Korea)

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KoreaScience (Korea)

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KoreaScience (Korea)

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KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

The objective of the Hanford Environmental Dose Reconstruction Project (HEDR) is to estimate the potential radiation doses received by people living within the sphere of influence of the Hanford Site. A potential critical pathway for human radiation exposure is through the consumption of waterfowl that frequent onsite waste-water ponds or through eating of fish, shellfish, and waterfowl that reside in/on the Columbia River and its tributaries downstream of the reactors. This document summarizes information on fish, shellfish, and waterfowl radiation contamination for samples collected by Hanford monitoring personnel and offsite agencies for the period 1945 to 1972. Specific information includes the types of organisms sampled, the kinds of tissues and organs analyzed, the sampling locations, and the radionuclides reported. Some tissue concentrations are also included. We anticipate that these yearly summaries will be helpful ...

International Nuclear Information System (INIS)

Absorption of lead is known to be enhanced during infancy. In this study, the sites of intestinal accumulation of Pb by suckling rats have been determined under various conditions using "2"0"3Pb as a tracer. When "2"0"3Pb was administered intragastrically (IG) as a soluble salt, accumulation occurred primarily in the duodenum, regardless of dose and vehicle. In contrast, when rat pups suckled from a dam which had received "2"0"3Pb, the only region of the small intestine showing accumulation of radioactivity was the ileum. To confirm that these differences were not related to the route of administration, rat milk was labeled with "2"0"3Pb and was then used for IG administration. Once again, accumulation (4 hr post-administration) was confined to the ileum. When the dose was increased 10-fold, milk Pb displayed some accumulation in duodenal tissue, but very much less than that of soluble Pb at the same time and dosage. At 20 ...

Science.gov (United States)

The effects of cocaine on the maternal and fetal pituitary-adrenal axis in vivo during pregnancy have not been reported. Six pregnant ewes and their fetuses underwent instrumentation at 113 to 119 days' gestation. Ewes were assigned to receive an intravenous bolus injection of vehicle or cocaine (0.5, 1.0, or 2.0 mg.kg-1) at 124 to 136 days' gestation. Maternal arterial blood gases, fetal pH and fetal PCO2 were unchanged after injection of cocaine or vehicle. After administration of 2.0 mg.kg-1 cocaine, arterial fetal PO2 fell 3.2 +/- 1.72 mm Hg (p less than 0.05) at +5 minutes, returning to baseline by +15 minutes. Maternal and fetal adrenocorticotropin levels rose within 5 minutes after the highest cocaine dose (p less than 0.05). There was a significant (p less than 0.05) increase in maternal cortisol at all doses of cocaine and in fetal cortisol at +15 minutes after the 2.0 mg.kg-1. PMID:1847006

International Nuclear Information System (INIS)

The Seismic Proving Test of Heavy Component with Energy Absorbing Supports has been conducted to prove the reliability of advanced seismic technology, supporting heavy component such as PWR steam generator with large capacity energy absorbing supports under the sponsorship of Ministry of Economical Trade and Industry. If energy absorbing supports are adopted for NPP heavy components, support structure of facility will be much simplified due to their seismic energy absorbing effect. The paper describes the results of lead damper element test and seismic test at Tadotsu Laboratory, using 1/2.5 scale PWR Steam Generator model supported by Lead Extraction Damper (LED) and development of characteristics evaluation formula of energy absorbing support. (author)

Energy Technology Data Exchange (ETDEWEB)

Natural radioactive materials under certain conditions can reach hazardous radiological levels. The natural radionuclide ({sup 238}U, {sup 232}Th, {sup 40}K) contents of rock samples at various locations in the North Tushki area were investigated using gamma-spectrometric analysis. Estimates of the measured radionuclide content have been made for the absorbed dose rate of gamma radiation. The equivalent radium (R{sub eq}) and the external hazard index (H{sub ex}) which resulted from the natural radionuclides in soil are also calculated and tabulated. The studied samples have been collected from various rock exposures in the North Tushki area. The distribution of major oxides, U and Th were studied. It is found that the enrichment and depletion of the major oxides are mainly due to the effect of hydrothermal alteration, which caused mobility of some major oxides, which increases some elements and decreases others. It is important to mention that ...

International Nuclear Information System (INIS)

Alanine/EPR Dosimetry system is classified as a reference-standard dosimeter which used to calibrate radiation environments and to calibrate routine dosimeters in absorbed dose range of 1 to 105 Gy. Characteristics of Alanine/EPR dosimetry system are better suitable than routinely used personnel dosimeters for the long term radiation measurement in harsh condition of Nuclear power plant : This system is not significantly affected by temperature and humidity and also has low fading rate. About 1 year ago, Alanine and Lithium compound dosimeters were installed at Wolsung unit 1 for the environment monitoring as a part of equipment qualification program. 35 positions which are most severe and representative cable positions were chosen for radiation and temperature monitoring. The recovered alanine dosimeter in the period of maintenance was measured by E-scan alanine analyzer system, Meanwhile measurement result shows extremely high radiation level ...

International Nuclear Information System (INIS)

Exposures from most natural and artificial sources, with the exception of those from medical radiology, are received at average dose rates of only a few microsieverts a day. Such risks as may be caused by these exposures are most unlikely to be determined with precision directly by epidemiological studies of populations exposed at these low rates. They may, however, be reliably inferred from the observed risks of exposure to rather larger doses delivered at higher dose rates in the light of the increasing knowledge of the phenomena involved in the initial cellular damage, the extent to which such damage is incorrectly repaired, and the processes which intervene between the genetic or other harm to cells and the likelihood of its final expression in inherited abnormality, in cancer development, or in defective foetal or embryonic growth. Current studies are of great importance, therefore, in examining ...

Energy Technology Data Exchange (ETDEWEB)

There is a continuing need to understand dose-response relationships for ionizing radiation in order to protect the health of the public and nuclear workers from undue exposures. However, relatively few human populations have been exposed to doses of radiation high enough to cause observable, long-term health effects from which to derive dose-response relationships. This is particularly true for internally deposited radionuclides, although much effort has been devoted to epidemiological studies of the few types of exposures available, including lung cancers in uranium miners form the inhalation of the radioactive decay products of Ra, liver cancers in patients injected with Thorotrast X-ray contrast medium containing Th, bone cancers in radium dial painters who ingested Ra, and bone cancers in patients who received therapeutic doses of Ra. These four types of exposures to internally ...

Energy Technology Data Exchange (ETDEWEB)

The feasibility of using desferrioxamine (DF), an iron chelator, as a therapeutic agent against paraquat (PQ/sup + +/) toxicity in male Sprague-Dawley rats was explored, based on the rationale of limiting toxic hydroxyl radical production from hydrogen peroxide by removing redox-active iron. Body weights, mortality, and lung histopathology were followed for periods up to 14 days after intraperitoneal injection of PQ/sup + +/ (20 or 25 mg/kg body weight) with or without concurrent daily subcutaneous injections of DF (300 mg/day). Animals receiving PQ/sup + +/ showed the expected typical patterns of mortality and of lung histopathology, namely: marked edema, subpleural hemorrhage, acute inflammation, perivascular mononuclear cell infiltrates, sloughing of alveolar and bronchiolar lining cells, and diffuse interstitial fibrosis. Desferrioxamine alone was non-toxic. Surprisingly, results when both PQ/sup + +/ and DF were administered indicated a failure of DF to ...

Energy Technology Data Exchange (ETDEWEB)

Background and Purpose: In an earlier phase II study, irradiation together with razoxane was shown to improve local control in recurrent rectal cancer. Therefore, the Austrian Society of Radiooncology (OeGRO) initiated a randomized controlled trial in 1992 to compare this combined treatment versus radiation therapy alone. Patients and Methods: Between 1992 and 1999, 36 patients with localized recurrences of rectal cancer were randomized to receive radiotherapy without (group A) or with razoxane (group B). The prognostic variables of the two groups were similar except for a longer median latency period from initial surgery to local recurrence in group A. High-energy photons with daily fractions between 170 and 200 cGy were used. The median total radiation dose was 60 Gy in each group. The patients in group B received a median razoxane dose of 9.6 g (range, 5-12 g). Main outcome measures were local ...

International Nuclear Information System (INIS)

Full text: Introduction. Children, especially premature infants and neonates, are at a much higher risk to obtain an X ray induced disturbance of life - particularly cancer. On the one hand this is due to their longer life expectancy and on the other hand it is due to their higher cell proliferation rate. The paediatric radiology unit of the Inselspital Bern recently installed some of the most advanced X ray equipment nowadays available. It is based on the two latest digital technologies: double read computed radiography (CR) and direct digital radiography (DR). Only the implementation of these digital radiography systems permits the digital acquisition and additionally the analysis of acquired data. The systematic analysis of large amounts of biometric data and exposition data is the basis for further dose reduction and a systematic quality control (QC). Patients are increasingly critical concerning radiation exposure - especially parents regarding their children. ...

International Nuclear Information System (INIS)

Full text: Production: This radio iodine produced by three methods: 1) Wet method: The irradiated tellurium is dissolved in an oxidizing mixture which also converts iodine in to iodide. This is a chemical method and iodine that it produced with this method has low purity and efficiency. 2). Dry Method: The irradiated tellurium is dissolved in furnace (750 deg. C) with sublimation method and iodine absorbed in sodium solution . In this case we have more than 99.5 % purity and 80 % efficiency. We are using this type in Iran. 3) Fission fragment method: In this case the iodine separated from fission fragment directly and we have high purity (career free) and specific activity of iodine. Application: Iodine is a versatile tracer element. It is used to determine thyroid cancer metastases, and size, shape and activity of the thyroid gland. Critical organ of iodine is thyroid gland. One of the common diagnostic procedures for determining thyroid function therefore, is to ...

Energy Technology Data Exchange (ETDEWEB)

A number of ion exchange materials are being evaluated as part of the Tank Waste Remediation System (TWRS) Pacific Northwest Laboratory (PNL) Pretreatment Project for the removal of {sup 137}Cs from aqueous tank wastes. Two of these materials are organic resins; a phenol-formaldehyde resin (Duolite CS-100) produced by Rohm and Haas Co. (Philadelphia, Pennsylvania) and a resorcinol-formaldehyde (RF) resin produced by Boulder Scientific Co. (Mead, Colorado). One of the key parameters in the assessment of the organic based ion exchange materials is its useful lifetime in the radioactive and chemical environment that will be encountered during waste processing. The focus of the work presented in this report is the radiation stability of the CS-100 and the RF resins. The scope of the testing included one test with a sample of the CS-100 resin and testing of two batches of the RF resin (BSC-187 and BSC-210). Samples of the exchangers were irradiated with a {sup 60}Co source to a total ...

Energy Technology Data Exchange (ETDEWEB)

To evaluate a dose conversion factor from the `Working Level of Month` (WLM) of radon to the absorbed dose (mGy), the quality of radon and its progeny was assessed, and exposures controlled for each deposition region were planed as follows: 1) exposure of radon gas to the entire respiratory tract, 2) exposure of `unattached` fractions to the upper respiratory tract, 3) exposure of `attached` fractions onto ultrafine particles to the deep lung, 4) exposure of `attached` fractions onto fine particles to the lower respiratory tract, 5) exposure of `attached` fractions onto coarse particles to the upper respiratory tract. In this preliminary study, a prototype exposure system of radon and its progeny for small rodents was designed. A whole body exposure chamber with a volume of about 0.5 m{sup 3} was used, which it held 20 rats. The aging and mixing chamber separated by the exposure chamber had a volume of about 1 m{sup 3}. As ...

International Nuclear Information System (INIS)

Cinnabar, a naturally occurring mercuric sulfide (HgS), has long been used in combination with traditional Chinese medicine as a sedative for more than 2000 years. Up to date, its pharmacological and toxicological effects are still unclear, especially in clinical low-dose and long-term use. In this study, we attempted to elucidate the effects of cinnabar on the time course of changes in locomotor activities, pentobarbital-induced sleeping time, motor equilibrium performance and neurobiochemical activities in mice during 3- to 11-week administration at a clinical dose of 10 mg/kg/day. The results showed that cinnabar was significantly absorbed by gastrointestinal (G-I) tract and transported to brain tissues. The spontaneous locomotor activities of male mice but not female mice were preferentially suppressed. Moreover, frequencies of jump and stereotype-1 episodes were progressively decreased after 3-week oral administration ...

International Nuclear Information System (INIS)

Electron beams as a source of directed energy are under study at the Lawrence Livermore National Laboratory (LLNL). An intense 10-kA, 50-MeV, 50-ns full-width half-maximum, pulsed electron beam is generated by the prototype Advanced Test Accelerator (ATA) at the Laboratory's Site 300. Whenever the electron beam is stopped in materials, intense radiation is generated. Estimates based on available data in the literature show that for materials such as lead, photon radiation (x ray, gamma, bremsstrahlung) levels can be as large as 10"4 roentgens per pulse at 1 m in the zero-degree direction (i.e., the electron-beam direction). Neutrons, which are emitted isotropically, are produced at a level of 10"1"3 n/m"2 per pulse. Depending upon the number of pulses and the shielding geometry, the accumulated dose is potentially lethal to personnel and potentially damaging to instrumentation that may be used for diagnostics. To provide shielding for minimizing the risk of ...

Energy Technology Data Exchange (ETDEWEB)

Full text: This presentation will review the progress achieved so far by the Irish national regulatory agency, the Radiological Protection Institut e of Ireland (R.P.I.I.) in the investigation of work activities where the presence of natural radiation sources (NORM) could lead to a significant increase in exposure to workers or members of the public which cannot be disregarded from the radiation protection point of view. Since the coming into force in Ma y 2000 of the Radiological Protection Act, 1991 (Ionising Radiation) Order, 2000 (S.I. No. 125 of 2000) which implements the Eu B.S.S. Directive 96/29/EURATOM, four major NORM industries currently active in Ireland have been investigated. According to the literature, they are all considered liable to involve work practices resulting in exposure to NORM. They include: the gas extraction and production industry, the peat- and coal-firing power generation industry and the bauxite/alumina refining industry. For the gas industry, monitoring ...

International Nuclear Information System (INIS)

Beagle dogs were given single, whole-body "6"0Co gamma-radiation exposures at one of three prenatal (8, 28, or 55 days postcoitus) or three postnatal (2, 70, or 365 days postpartum) ages to evaluate the relative radiosensitivity of various stages of brain development. A total of 387 dogs received mean doses ranging from 0.16 to 3.83 Gy, and 120 dogs were sham-irradiated. Groups of dogs were sacrificed at preselected times from 70 days to 11 years of age. Brain weight decreased significantly with increasing dose in dogs irradiated at 28 or 55 days postcoitus or at 2 days postpartum. Irradiations at 28 days postcoitus were dramatically more effective in causing a reduction in brain weight than those at 55 days postcoitus or 2 days postpartum. Among dogs given 1.0 Gy or more and followed for up to 4 years, there was a radiation effect evident at all three sensitive exposure ages. Among dogs given lower ...

Science.gov (United States)

The effects of felbamate on the pharmacokinetics of a low-dose combination oral contraceptive containing 30 micrograms ethinyl estradiol and 75 micrograms gestodene were assessed in a randomized, double-blind, placebo-controlled parallel-group study in healthy premenopausal female volunteers established in a regimen of oral contraceptive use. They received either placebo or 2400 mg/day felbamate from midcycle (day 15) to midcycle (day 14) of two consecutive oral contraceptive cycles (months 1 and 2). Pharmacokinetic assessments of ethinyl estradiol and gestodene were performed on day 14 of both cycles. To determine whether ovulation occurred, plasma progesterone and urinary luteinizing hormone levels were measured, and diaries recording vaginal bleeding were kept. Felbamate treatment resulted in a significant 42% decrease in gestodene area under the plasma concentration-time curve (0 to 24 hours) (p = 0.018) compared with baseline, whereas a ...

Energy Technology Data Exchange (ETDEWEB)

The radionuclide characteristics of light-water-reactor (LWR) spent fuel play key roles in the design and licensing activities for radioactive waste transportation systems, interim storage facilities, and the final repository site. Several areas of analysis require detailed information concerning the time-dependent behavior of radioactive nuclides including (1) neutron/gamma-ray sources for shielding studies, (2) fissile/absorber concentrations for criticality safety determinations, (3) residual decay heat predictions for thermal considerations, and (4) curie and/or radiological toxicity levels for materials assumed to be released into the ground/environment after long periods of time. The crucial nature of the radionuclide predictions over both short and long periods of time has resulted in an increased emphasis on thorough validation for radionuclide generation/depletion codes. Current radionuclide generation/depletion codes have the capability to follow the ...

International Nuclear Information System (INIS)

Random motion of a particle, emitting and absorbing tachyons, is investigated. It is shown that if bradyon is in equilibrium with neutral gas, i.e. it absorbs and emits tachyons, which do not have any charges, tha particle with each absorption-emittance of a tachyon changes its energy and momentum, never varying its own mass, and as a result it moves like a brownian particle. Thus, bradyon, interacting with tachyon gas, increases its momentum continuously in agreement with the Einstein-Fokker-Planck type equation.

Energy Technology Data Exchange (ETDEWEB)

To determine the presence, prevalence, and clinical importance of /sup 99m/Tc pertechnetate uterine uptake, this retrospective analysis of 71 Meckel's scans was undertaken. Specifically, each study was evaluated for the presence of a focal accumulation of radiotracer cephalad to the bladder. Patients received an intravenous dose of 150 microCi/kg of /sup 99m/Tc pertechnetate. Each study consisted of 15 one minute anterior serial gamma camera images, and a 15, 30, and 60 minute anterior, right lateral and posterior scintiscan. Menstrual histories were obtained from all patients except two. No males (33/33), nor premenstrual (13/13), menopausal (4/4) or posthysterectomy (2/2) patients revealed a uterine blush. Eleven of 15 patients (73%) with regular menses demonstrated a uterine blush. They were in the menstrual or secretory phases of their cycle. Four demonstrated no uterine uptake, had regular periods, but were in the proliferative ...

British Library Electronic Table of Contents (United Kingdom)

We evaluated the use of a novel gene porter (Den123-a nontoxic self-assembled dendritic spheroidal nanoparticle made of biodegradable monomers), aiming to enhance and improve the desired immune response in protection from allergy. Footpad DNA immunization in Balb/c mice was done three times using the Bet v 1a gene with or without Den123 with 2-week intervals followed by sensitization with rBetv1 (5mg) in alum twice in a weekly interval. Different doses of pCMV-Betv1 were used (10mg and 100mg). The protective role of different formulations was evaluated by measuring the IgG1, IgG2a and IgE antibody production, cytokine release of isolated splenocytes and b-hexosaminidase release from the RBL cells. Higher and increasing ratios of IgG2a/IgG1 were seen in mice which received plasmids in combi...

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The use of ionising radiation for the preservation of food has been under investigation for many years but has yet to receive worldwide acceptance. Although irradiation can be carefully controlled, it is generally accepted that the development of a test or tests for the detection of irradiated food would enhance consumer confidence and might help to enforce labelling regulations. The 2-alkylcyclobutanones are reported to be the only cyclic compounds formed as the products of the radiolysis of saturated and unsaturated triglycerides. The synthesis of 2-dodecylcyclobutanone (DCB) and 2-tetradecylcyclobutanone (TCB), which are formed from palmitic and stearic acid respectively following irradiation, has been carried out and using irradiated chicken meat as the model for a high-lipid containing food, both cyclobutanones have been extracted with hexane and then identified using gas chromatography/mass spectrometry (GC/MS). DCB and TCB have been detected in chicken meat ...

British Library Electronic Table of Contents (United Kingdom)

The aim of this pilot study was to evaluate the feasibility of long-term subcutaneous application of low-dose IL-2 in children with malignancies at very high risk of relapse who underwent highly T cell and B cell depleted HLA-identical (MUD) or full haplotype mismatched related hematopoetic stem cell transplantation. We studied 11 patients with acute leukemias/myelodysplastic syndrome and juvenile myelomonocytic leukemia (active disease and/or second stem cell transplantation, n = 8; >=CR 2, n = 2) and relapsed or progressive Ewings sarcoma (n = 2) who received prophylactic IL-2 treatment for a high probability of disease recurrence after allo-HSCT. Toxicities from IL-2 were transient fever, fatigue and local inflammation. In one patient GvHD grade III with no clear association to IL-2 adm...

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This work is a retrospective study of 86 patients with squamous cell (51) and basal cell (35) carcinoma of the face. The median age was 67 years. The staging is as following: 31 cases T{sub 1} and T{sub 2}, 55 patients T{sub 3} and T{sub 4}. All patients were considered NO. Electron beam was used in all cases and energy ranged from 5 to 15 MeV depending on the thickness of the tumor. The total tumor dose was 60-70 Gy delivered in 6 weeks. In 7 cases of very old patients the authors have used concentrated irradiation: 3 patients received 21 Gy in one fraction and 4 patients 48 Gy in 8 fractions. 96.8% patients T{sub 1} i T{sub 2} are NED contrary to 56.4% T{sub 3} i T{sub 4}. Cosmetic results were considered as good in 52, fairly good in 7 and bad in 2 patients.

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The effects of fine-particle C, such as diesel soot, on the optical properties of urban haze in the visible wavelength range were explored to determine the dominant effects and to see if simple parameters (such as visual range in green) provide an adequate measure of these effects. It is known that fine-particle C absorbs more strongly in the blue than in the red, so that when it is mixed with a white pigment, the resulting gray can appear somewhat brown. The possibility of a similar effect in urban hazes was investigated, but found not to occur. When the sun is overhead, the near-horizon sky chromaticities caused by mixtures of fine-particle C and non-absorbing aerosol can also be produced by non-absorbing aerosols alone. It is shown that absorbing aerosol will darken the horizon sky, and a simple equation for the radiance of the horizon sky is derived. The effect of absorbing ...

International Nuclear Information System (INIS)

This report deals with the preliminary results of trials in the DATECA project with stage I, II and III patients with non-seminomatous germ cell tumours. Stage 1 patients were randomized between infradiaphragmatic irradiation and observation. No significant difference in recurrence rates has been observed as yet. Eighteen of 95 patients had recurrence with a median time to relapse of 3 months. Fifteen patients achieved complete remission after treatment by combiantion chemotherapy while 3 patients are still undergoing treatment. Stage II patients received 6 series of cis-platinum, bleomycin, and vinblastine. The patients were initially randomized to receive chemotherapy alone versus chemotherapy plus irradiation. Irradiation led to increased toxicity and decreased doses of the antineoplastic drugs. Fifty-one patients were studied. The overall complete remission rate was 89 per cent including 7 patients who achieved complete ...

UK PubMed Central (United Kingdom)

Background and objectives: Patients receiving dialysis have a high burden of cardiovascular disease. Some receive coronary artery revascularization but the optimal method is controversial.Design,...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A model for energy transport in a solid particle cavity receiver is developed and applied to the design and analysis of a receiver for the Central Receiver Test Facility (CRTF), Albuquerque, New Mexico. The model gives thermal performance results - including particle temperatures, cavity efficiencies, and wall temperatures - which directly affect the economic and technical feasibility of a solid particle receiver. In addition, design criteria relevant to the configuration of a solid particle cavity receiver are developed. Results for CRTF indicate that at design conditions particle temperatures will exceed 1200/sup 0/K with cavity efficiencies on the order of 75%.

International Nuclear Information System (INIS)

... dose rates inhalation iodine 134 krypton 88 nuclear decay quality factor

International Nuclear Information System (INIS)

The aim of this study was to evaluate the results of postoperative radiotherapy in a case of perihilar cholagiocarcinoma by analyzing overall survival rate, patterns of failure, prognostic factors for overall survival, and toxicity. Between January 1998 and March 2008, 38 patients with perihilar cholangiocarcinoma underwent a surgical resection and adjuvant radiotherapy. The median patient age was 59 years (range, 28 to 72 years), which included 23 men and 15 women. The extent of surgery was complete resection in 9 patients, microscopically positive margins in 25 patients, and a subtotal resection in 4 patients. The tumor bed and regional lymphatics initially received 45 Gy or 50 Gy, but was subsequently boosted to a total dose of 59.4 Gy or 60 Gy in incompletely resected patients. The median radiotherapy dose was 59.4 Gy. Concurrent chemotherapy was administered in 30 patients. The median follow-up period was 14 months ...

Science.gov (United States)

Purpose: Photodynamic therapy (PDT) is based on the interaction of a photosensitizing (PS) agent, light, and oxygen. Few new PS agents are being developed to the in vivo stage, partly because of the difficulty in finding the right treatment conditions. Response surface methodology, an empirical modeling approach based on data resulting from a set of designed experiments, was suggested as a rational solution with which to select in vivo PDT conditions by using a new peptide-conjugated PS targeting agent, neuropilin-1. Methods and Materials: A Doehlert experimental design was selected to model effects and interactions of the PS dose, fluence, and fluence rate on the growth of U87 human malignant glioma cell xenografts in nude mice, using a fixed drug-light interval. All experimental results were computed by Nemrod-W software and Matlab. Results: Intrinsic diameter growth rate, a tumor growth parameter independent of the initial volume of the tumor, was selected as ...

International Nuclear Information System (INIS)

This paper is a progress report on the role of radiation therapy (RT) in local tumor control and the decreased incidence of pulmonary metastasis in 251 patients entered in the Intergroup Ewing's Sarcoma Study. All were followed for more that 1 year, and their RT records were reviewed. Doses to the primary tumor in the range of 4,500--6,500 rad were administered over approximately 5 to 6 weeks in combination with 4 drugs, i.e., vincristine (VCR), dactinomycin (DAC), cyclophosphamide (CY), and adriamycin, or only the first 3. One group of patients received the 3 drugs and bilateral pulmonary irradiation (approximately 1,500 rad in 2 wk). Preliminary analysis showed a local primary tumor control of approximately 90%. Patients with lesions in the pelvis and humerus had local failure rates of 13% (7 of 54) and 21.4% (6 of 28), respectively. The treatment groups differed significantly in the incidence of pulmonary metastasis. Patients treated with ...

Science.gov (United States)

The epileptogenic and neurodegenerative effects of gamma-dendrotoxin, from Dendroaspis angusticeps, a specific blocker of a non-inactivating, voltage-sensitive K+ channel, were studied after focal injection into one dorsal hippocampus in rats pretreated with CGP040116, a N-methyl-D-aspartate (NMDA) receptor antagonist, and in rats bearing a monolateral surgical lesion of the Schaffer collaterals whose terminals originate from CA3 pyramids and release glutamate in the CA1 hippocampal area. Administration of 35 pmol gamma-dendrotoxin elicited in all of the treated animals (n=8) bilateral EEG discharges and damage to the hippocampal formation. Quantitation of the damage revealed significant bilateral neuronal cell loss in the CA1, CA3 and CA4 pyramidal cell layers. The lowest dose (0.35 pmol; n=4) of the toxin used did not affect EEG activity and failed to cause significant hippocampal cell loss whereas the 3.5 pmol (n=6) dose caused EEG seizures ...

Energy Technology Data Exchange (ETDEWEB)

The Tomographic Gamma Scanning (TGS) technique is a relatively new method in the field of non-destructive assay (NDA) of radioactive waste. The TGS technique combines High Resolution Gamma Spectrometry (HRGS) with Three-Dimensional (3-D) low spatial resolution transmission and emission image reconstruction techniques to achieve assay goals. When compared to the traditional methods such as Segmented Gamma Scanning (SGS), the TGS technique can yield better accuracies for cases where the radionuclide is distributed non-uniformly in a heterogeneous matrix. The TGS technique is ideally suited for low-to-moderate density waste matrices, say 1.0 g cm{sup -3} or below for 55 US gal. drums, although it can be extended to higher densities by using alternative approaches to the design or analyses. Recently Canberra Industries designed, built and characterized four such TGS systems for nuclear power plant applications. Many of the design features and the end application itself set these TGS ...

Energy Technology Data Exchange (ETDEWEB)

Objective: To evaluate technical feasibility and acute and subacute radiotolerance of a self-expandable stent loaded with {sup 125}I seeds in the rabbit esophagus. Methods: A self-expandable stent designed for esophageal application was made of 0.16 mm nitinol wire and loaded with {sup 125}I seeds (CIAE-6711). Twenty-seven stents with three different radioactive dosages (n = 9 in each dosage group) were implanted in the esophagus of healthy rabbits, while nine stents alone were used as controls. The stents were perorally deployed into the esophagus under fluoroscopic guidance. Radiological follow-up included plain chest film, CT scan, and barium esophagography which were undertaken in all rabbits of each group at 2, 4, and 8 weeks, respectively, which were correlated to histopathological findings. The stented esophageal segments along with their adjacent tissues were harvested for histopathological examinations. Results: The stent was successfully deployed into the targeted esophageal ...

International Nuclear Information System (INIS)

The mechanism of lead transport is presented, and especially the particular similarities or dissimilarities between lead and calcium in this process. The absorption of these metals was determined cockerels, raised on a commercial diet or on a specified diet, using in vivo ligated loop procedure. The dose administered into the loop contained 0.5 #mu#Ci "2"0"3Pb (and/or 0.1 #mu#Ci "4"7Ca), and 0.01 mM lead acetate (and/or mM CaCl_2) in 0.5 ml 0.15 M NaCl,pH 6.5. It was shown that lead is rapidly taken up by the mucosal tissue, and slowly transferred into the body, whereas less calcium is retained by the tissue and the transfer of calcium is many times as effective as that for lead. They appear to respond in a similar manner to a low calcium intake and vitamin D treatment. Increasing luminal stable lead concentration significantly reduced the percentage of radiolead significantly reduced the percentage of radiolead absorbed, but did not affect the ...

Energy Technology Data Exchange (ETDEWEB)

The transfer of 203Pb and/or 47Ca across the intestinal epithelium of the chick was investigated, with emphasis given to the functional role of cholecalciferol (vitamin D-3). 203Pb, after introduction in the intestinal lumen, is rapidly accumulated by the intestinal tissue, and only a fraction of 203Pb is translocated parenterally (absorbed). Cholecalciferol did not significantly affect the accumulation of 203Pb by intestinal tissue but did accelerate 203Pb movement across the basal-lateral membrane. In contrast, cholecalciferol both decreased 47Ca tissue levels and increased 47Ca absorption. In rachitic chicks, the rate of absorption of 203Pb was greater in the distal than in the proximal segments of the intestine; after cholecalciferol repletion, the degree of absorption in al segments was similar, indicting the order of cholecalciferol effectiveness as duodenum greater than or equal to jejunum greater than ileum. An acute dose of 1,25(OH)2D3 ...

Energy Technology Data Exchange (ETDEWEB)

The absorbed dose delivered to the patient in brachytherapy is directly proportional to the source strength in terms of the reference air-kerma rate (RAKR). Verification of this quantity by the hospitals is widely recognized as an important part of a quality assurance program. An external audit was performed on behalf of the Secondary Standard Dosimetry Laboratory at the Swedish Radiation Protection Authority (SSI). The aim was to investigate how accurately the source-strength in 192Ir brachytherapy is determined at Swedish hospitals. The SSI reference well-type ion chamber and calibrated equipment were used to measure the RAKR of an 192Ir source in each of the 14 Swedish afterloading units. Comparisons with values determined by vendors and hospitals were made. Agreement in values of RAKR as determined by SSI, hospitals and vendors were in all cases within the +-3% uncertainty (at a coverage factor of k=2), typically guaranteed by the vendors. ...

Energy Technology Data Exchange (ETDEWEB)

Thermal absorption with its combined thermal and mechanical loads in a solar receiver does depend significantly on the distribution of incident solar radiation. For a cavity receiver with paraboloid collectar a method is derived which enables the calculation of solar radiation distribution on the areas inside the receiver. The theoretical bases are presented first, and a subsequent example shows the influence of the most important geometric parameters on the distribution of solar radiation.

Energy Technology Data Exchange (ETDEWEB)

A preliminary study of two different kinds of solar receivers (a rotating cavity receiver and a volumetric receiver) suitable to operate in the 1 kW solar facility at the University of Rome is presented. Possible applications of solar energy in the aluminum extraction from leucite and chemical storage by the CuO/Cu[sub 2]O cycle are presented and discussed. (author).

Wastenet

all Certified ESM facilities capable of receiving used mobile phone waste from non-Annex VII countries.

Energy Technology Data Exchange (ETDEWEB)

A thermal analysis of the Omnium-G receiver is presented and the technique is shown to be generally applicable to solar thermal receivers utilizing a directly heated thermal mass. The thermal loss coefficient, including reradiation losses, is calculated and shown to agree quite well with the experimentally measured thermal loss coefficient. The rate of heat transfer to the working fluid is also analyzed and the analysis is used to show that the Omnium-G receiver is well matched to the water/steam working fluid because the steam outlet temperature is almost the same as the receiver temperature. A general procedure for calculating receiver performance is presented. With this procedure, the energy delivery to any working fluid, the delivered temperature of the working fluid, and the pressure drop through the receiver can be determined. An example of the calculation ...

Energy Technology Data Exchange (ETDEWEB)

The authors investigate the optimisation of solar-heated cavity receivers in which solar energy collected by a paraboloid collector is converted into electrical energy. The focussed solar energy enters the receiver through an aperture to heat the working fluid, which flows inside the receiver tubes and is compressed by the compressor of a gas turbine system, to the highest process temperature. A method of calculating the distribution on the inner receiver surfaces of the solar radiation reflected by the paraboloid collector is presented to begin with. The interchange of radiant energy inside the receiver cavity can be calculated on this basis, including the radiation loads, the temperatures of the inner receiver walls, and the radiative and convective losses. The temperature fields in the tube walls must be known for determining the strength required of ...

Energy Technology Data Exchange (ETDEWEB)

Use of hydrogen absorbing alloys in various practical applications is always connected with the problem of production of starting alloys. The transition from laboratory samples to small-scale production involves the change of furnace and its operation mode and this has an effect on the preparation method of mixture of starting metal. Also, for some applications such as thermosorption compressors the exact values of thermodynamical parameters of reaction are needed. In the present work we present the results of investigation of series Laves phase hydrogen-absorbing alloys which can be promising in for use in different devices. 1 ref.

Energy Technology Data Exchange (ETDEWEB)

An improved hybrid solar/combustion powered receiver of the type having an insulated housing with a front end and a rear end, a heat exchanger positioned adjacent the rear housing end for extracting heat energy out of the receiver, the insulated housing surrounding the heat exchanger and forming a receiver cavity, the housing also including an aperature having an aperture axis, the aperture located in the front housing end for admitting solar radiation to the cavity to impinge upon the heat exchanger, and a plurality of gas burners to provide combustion gases within the receiver.

International Nuclear Information System (INIS)

Full text: Thermoluminescence (TL) is a phenomenon of light emission caused by heating a pre-irradiated material. When ionizing radiation hits a TL material, electrons are freed from some atoms and moved in the material, leaving behind 'holes' of positive charge. Subsequently when the TL material is heated, the electrons and the 'holes' re-combine, and release the extra energy in the form of light. The light intensity can be measured, and related to the amount of energy initially absorbed through exposure to the ionizing radiation. In nineteen sixties thermoluminescence dosimeters (TLD) became popular for dosimetric applications in view of their small size, sensitivity and accuracy. Consequently, in early seventies, several countries started adopting of TLD for personnel monitoring. The idea of introducing TLD to replace the then prevalent film dosimeter for personnel monitoring in India was mooted and successfully implemented by Dr. K G Vohra. Limitations of ...

Science.gov (United States)

This paper presents the development and evaluation of field- controllable, semi-active magneto-rheological fluid (MRF) shock absorbers for a mountain bicycle. Recent trends in the bicycle industry show a movement towards semi-active suspension systems. Two new MRF dampers are designed and tested with the intent of being used on the front and rear suspension of a modern mountain bicycle. The MRF shock absorbers are designed to emulate the performance of the original equipment manufacturer shock absorbers in passive mode. Application of an input electric current to the MRF shock absorber causes a dramatic increase in the damping capacity. Procedures and results are presented for the design and experimental characterization of these MRF dampers.

Energy Technology Data Exchange (ETDEWEB)

An emergency shutdown system for high-temperature gas-cooled pebble-bed reactors is proposed in addition to the common absorber rod shutdown system. This system is based on the strongly absorbing effect of small boronated graphite spheres (called KLAK), which trickle in case of emergency by gravity from the top reflector into the reactor core. The inner reflector of the Siemens-Argonaut reactor was substituted by an assembly of spherical Arbeitsgemeinschaft Versuchsreaktor fuel elements, and the shutdown effect was examined by installing well-defined KLAK nests inside this assembly. The purpose was to develop and prove a calculational procedure for determining criticality values for assemblies of large fuel spheres and small absorbing spheres.

British Library Electronic Table of Contents (United Kingdom)

Abstract The characteristics of desulfurization and denitrification with composite absorbent were researched through aqueous absorption experiments. The removal efficiencies of SO2 and NO were up to 100 and 95%, respectively. The composite absorbent included NaClO2 and component M. Existence of component M in the solution could reduce the absorbent cost compared with using sodium chlorite alone. Chlorine dioxide, as main reaction intermediate product, participated in oxidation reaction. The optimal experimental conditions involved NaClO2 concentration of1.13 mmol/L, solution pH of 5.5, molar ratio (M/NaClO2) of 4.1, reaction temperature of 323 K. The optimal solution pH and reaction temperature were both in the required ranges of limestone-gypsum wet flue gas desulfurization (FGD) process....

KoreaScience (Korea)

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International Nuclear Information System (INIS)

Method for description of X-ray radiation dose distribution based on semiempirical description of dose fields is suggested. At that dose field description parameters can be easily individualized for concrete X-ray device.

International Nuclear Information System (INIS)

Else of solar energy as substitute for conventional fuels at a competitive cost requires efficient conversion from solar radiation to usable forms of energy. In solar thermal or thermochemical applications, high efficiency usually re- quires high temperature and high concentration of incoming radiation. The main form of energy loss from high temperature solar central receivers is thermal emission ('re radiation'), at an effective temperature close to the maximum receiver temperature. This loss is reduced if the aperture is divided into segments, most of which are maintained at lower temperatures. A two-stage partitioned receiver demonstrating this concept is under construction at the Weizman Solar Tower. The high-temperature stage is the DIAPR (Directly Irradiated Annular Pressurized Receiver). The low-temperature stage is made of tubular cavity receivers of simpler design. ...

International Nuclear Information System (INIS)

Dosimetric studies in 80 patients examined with the tomographic device 'Somatom' are reported. The gonad doses are compared to those of conventional radiographic techniques.

International Nuclear Information System (INIS)

Purpose: To determine if involved field radiation (IF) is equivalent to standard whole bone radiation (SF) in local tumor control; to establish patterns of failure following treatment; and to determine response, event free (EFS) and overall survival rates from multi-disciplinary therapy in Ewing's Sarcoma (ES). Materials and Methods: Between 1983 and 1988, 184 children with ES were enrolled onto POG 8346. 178 (97%) met eligibility criteria; 6 had non-ES pathology. Induction treatment of Cyclophosphamide/Adriamycin (C/A) x 12 weeks was followed by local treatment either surgery or radiation therapy (XRT) and C/A, Dactinomycin and Vincristine for 50 weeks. Resection was advised for patients with small primary tumors if accomplished without functional loss. 40 patients were randomized to receive SF, whole bone XRT to 39.6 Gy plus a 16.2 Gy boost (total 55.8 Gy) or IF to 55.8 Gy while 84 were assigned to IF XRT. Results: Of 179 eligible patients, 141 (79%) had ...

International Nuclear Information System (INIS)

A simple dose-saving procedure for the diagnosis of congenital hip dysplasia employing a diaphragm in nearfocus position is presented. Doses to the skin and the gonads were measured with a phantom for the new and other techniques. With optimal techniques the skin dose is smaller than 2 mR and the gonadal doses lie around 0.1 mR for both male and female patients. An estimate of the dose burden from undesired radiation is appended. (orig.).

British Library Electronic Table of Contents (United Kingdom)

An energy transfer and conversion model for high-temperature solar cavity receivers has been developed using the transport behaviour of solar radiation as described by the spectral radiative exchange factors. A Monte-Carlo ray-tracing method coupled with optical properties was adopted, to predict radiation characteristics of the solar collector system by calculating radiative exchange factors. A cavity receiver with a plano-convexo quartz window was proposed, based upon the directional characteristics of the focal flux and the redistribution effect of the quartz window. Parametric studies on the windowed receiver provided a more uniform flux distribution, higher efficiency and lower loss than the windowless receivers. The predicted results serve as a design reference for the solar receiver...

Energy Technology Data Exchange (ETDEWEB)

Results from a numerical model of axisymmetric solar cavity receivers are compared with experimental data for tests of a novel test bed receiver in the Saudi National Laboratories solar furnace. The computed energy transfer rates and temperatures are compared with the experimental data for different receiver geometries, aperture sizes, and operating conditions. In general, the agreement between the numerical model and the experimental data is better for the small-to-midsized apertures than for the large apertures. The analysis indicates that for the larger apertures, the convective heat losses are overpredicted. It also suggests that these losses could be better characterized. Sensitivity analyses show that both the total solar energy input rate and the convective heat-loss coefficient significantly affect the receiver thermal performance and that the distribution of the input solar flux significantly ...

International Nuclear Information System (INIS)

The use of absorbable polyglactin 910 mesh (Vicryl) is described in a case of Ewing's sarcoma of the pelvis. An operation was performed to hold the small bowel and colon out of the pelvis for a temporary period during which radical radiotherapy was delivered. The mesh allowed the temporary displacement of bowel and obviated bowel radiation morbidity. (author).

Energy Technology Data Exchange (ETDEWEB)

The brochure reports on the construction and method of operation of heat pumps: - Efficiency and temperature difference - output figure - circuit processes - saving of primary energy - monovalent and bivalent plants - absorber, earth collectors - heat recovery. (HW) [Deutsch] Die Broschuere berichtet ueber den Aufbau und die Wirkungsweise von Waermepumpen: - Wirkungsgrad und Temperaturdifferenz - Leistungszahl - Kreisprozesse - Einsparung von Primaerenergie - monovalente und bivalente Anlagen - Absorber, Erdkollektoren - Waermerueckgewinnung. (HW)

Energy Technology Data Exchange (ETDEWEB)

LEDF(Large Equipment Dismantling Facility) is the solid waste processing technology development facility that carries out high-volume reduction and low dosage processing. The high-volume reduction processing of the high dose {alpha}-waste configured with combustible waste, pvc and rubber, spent ion exchange resin, and noncombustible waste have been planned the incinerating and melting facility using the in-can type high frequency induction heating in LEDF. This test is intended to clarify the design data. It was confirmed that the incinerating and melting performance, molten solid properties and exhaust gas processing performance with pilot testing equipment and bench scale equipment. The result of this test are as follows. 1. Processing speed is 6.7 kg/h for the combustible waste, 13.0 kg/h for the ion exchange resin, and 30.0 kg/h for the noncombustible waste. For above optimum processing conditions are as follows. Operating temperature is 1000degC for the ...

Science.gov (United States)

Thermal Cavity Receivers,". JPL. Publication. 83-97,. 1983. 5Hall, III, C.A., Glakpe, E.K., Cannon,. J.N., and. Kerslake,. T.W., "Modeling ...

Energy Technology Data Exchange (ETDEWEB)

The United States and Russia have agreed to jointly develop a solar dynamic (SD) system for flight demonstration on the Russian Mir space station starting in late 1997. Two important components of this SD system are the solar concentrator and heat receiver provided by Russia and the US, respectively. This paper describes optical analysis of the concentrator and solar flux predictions on target receiver surfaces. The optical analysis is performed using the code CIRCE2. These analyses account for finite sun size with limb darkening, concentrator surface slope and position errors, concentrator petal thermal deformation, gaps between petals, and the shading effect of the receiver support struts. The receiver spatial flux distributions are then combined with concentrator shadowing predictions. Geometric shadowing patterns are traced from the concentrator to the target receiver surfaces. ...

International Nuclear Information System (INIS)

''Paraquat lung'' which is complicated with paraquat poisoning has been a lethal pulmonary pathology presenting intra-alveolar fibrosis, but an effective therapy has not been developed so far. We hypothesized that the type II alveolar cells producing surfactant were damaged by paraquat which was actively accumulated through out the blood by alveolar epithelial cells. To prove this hypothesis, we examined the effect of an intratracheal administration of an artificial lung surfactant (surfacten, Mitsubishi Tanabe Pharma Corporation, Osaka) on mortality in a model of murine paraquat poisoning. Paraquat was given intramuscularly 3 days after the intratracheal surfactant administration. The mice used were C57BL/6J strain and Balb/C strain. The lethal dose, 50% (LD50), of paraquat was about 28 mg/kg in the C57BL/6J strain and about 9 mg/kg in the Balb/C strain, respectively. Mortalities of paraquat poisoning in both strains of mice improved significantly when the mice ...

Science.gov (United States)

A series of radioactive catastrophes (from 1948 to 1967) in the Southern Urals in the USSR led to intensive environmental contamination. Radioactive wastes were dispersed over the 20000 km(2) territory of four provinces-Chelyabinsk, Sverdlovsk, Tyumen' and Kurgan-due to the activity of the military facility that was built in 1948 for the production of nuclear bomb plutonium. The results of 50 years of investigations into the consequences of these disasters allow a general picture of the events that occurred to be reconstructed and allow the medical consequences of the irradiation of about half a million residents to be depicted. However, due to the atmosphere of secrecy and inadequate medical procedures, the results of medical studies of radiation victims are scant. The current protocols present a unique opportunity to study the DNA damage at the nucleotide resolution level in the genome of inhabitants of the given region, who presumably received chronic ...

Energy Technology Data Exchange (ETDEWEB)

The microbiological safety, refrigeration shelf-life, and nutritional quality of chicken breast meat were investigated following combined electron-beam irradiation and cooking under vacuum (sous-vide). Chicken breast meat inoculated with 10{sup 6} CFU/g of Listeria monocytogenes was irradiated with an electron beam at doses up to 3.1 kGy under vacuum in barrier bags, cooked in a boiling water bath for 3 min 45 s (previously determined to achieve an internal temperature of 71.1{sup o}C), and stored at 8{sup o}C for up to 5 weeks. Listeria was undetectable in samples treated with combined sous-vide and irradiation at 3.1 kGy, but the organism survived the sous-vide treatment without irradiation and multiplied during storage. A similar study, conducted with uninoculated chicken breast meat, revealed that the product which received both irradiation (3 kGy) and sous-vide treatment had a shelf-life of at least 8 weeks at 8{sup o}C, whereas the ...

International Nuclear Information System (INIS)

Background and purpose: We evaluate the feasibility of concomitant and adjuvant docetaxel combined with three-dimensional conformal radiotherapy (3D-CRT) and androgen deprivation in high-risk prostate carcinomas. Methods: Fifty men with high-risk localized prostate cancer (16), locally advanced (28) or very high-risk prostate cancer (6) were included. Seventy Gy were delivered on prostate and seminal vesicles in 35 fractions, concurrently with weekly docetaxel (20 mg/m"2). Three weeks after the completion of 3D-CRT, docetaxel was given for 3 cycles (60 mg/m"2), every 3 weeks. Patients had to receive LHRH agonist during 3 years. Results: The intent to treat analysis shows that four patients out of 15 stopped prematurely the chemotherapy due to grade 3-4 acute toxicity. In the per protocol analysis, 46 patients completed a full-dose chemoradiation regimen representing 413 cycles: five patients experienced a grade 3 toxicity, and 15 patients ...

International Nuclear Information System (INIS)

High energy physics facilities must monitor the radiation doses received by their personnel. This monitoring can only be effective if the radiation detection devices can be calibrated with a good degree of accuracy. Radiation fields are usually composed of several types of radiation, including gamma rays, beta radiation, neutrons, etc. The neutron detection instruments respond not only to the neutrons coming directly from the source but also those scattered from the floor, walls, and ceiling. The amount of neutron scattering varies from site to site depending on the construction materials and layout of the building. The purpose of this study was to determine the scattered neutron fraction in the central volume of the calibration mezzanine of the Radiation Physics Calibration Facility (RPCF) at the Fermi National Accelerator Laboratory (Fermilab). At Fermilab, radiation workers dosimeters use CR39 for neutron detection, which are sent to an ...

Energy Technology Data Exchange (ETDEWEB)

US Department of Energy (DOE) Order 5820.2A (DOE, 1988) requires performance assessments on all new and existing low-level radioactive waste (LLW) disposal sites. An integral part of performance assessment is estimating the fluxes of radioactive gases such as radon-220 and radon-222. Data needs pointed out by mathematical models drive site characterization. They provide a logical means of performing the required flux estimations. Thorium-230 waste, consisting largely of thorium hydroxide and thorium oxides, has been approved for disposal in shallow trenches and pits at the LLW Radioactive Waste Management Site in Area 5 of the Nevada Test Site. A sophisticated gas transport model, CASCADR8 (Lindstrom et al., 1992b), was used to simulate the transport and fate of radon-222 from its source of origin, nine feet below a closure cap of native soil, through the dry alluvial earth, to its point of release into the atmosphere. CASCADR8 is an M-chain gas-phase radionuclide transport and fate ...

Energy Technology Data Exchange (ETDEWEB)

Solar heating of gas turbine plants steps back more and more into the focus of current research. The mainly instationary operation of solar turbine power plants can only be predicted with sufficient accuracy if the transient behaviour of the receiver for the solar radiation is known. Therefore the transient behaviour of cavity receivers of different design is investigated. The mathematical model used for the simulation of the heat transfer and energy storage processes is illustrated. Computed results for receivers with various inner lining are compared and evaluated concerning their use in practice.

Science.gov (United States)

... mounted new operations against the TTP stronghold in ... was the fourth tranche of Pakistan's IMF-backed ... and brought the total funds received by ...

Science.gov (United States)

with full-scale component test data, a final requirement for completing general materials selection criteria. It also should be pointed out that, ...

Science.gov (United States)

An electric power generating apparatus is described, including: a solar collector; a primary thermal loop including primary thermal fluid; a cavity receiver to receive reflected solar energy from the solar reflector, convert the solar energy into thermal energy, and transmit the thermal energy to the primary thermal fluid by heating the primary thermal fluid not to exceed a given temperature, the given temperature being substantially equal to 700 F; a Stirling engine receiving the primary thermal fluid heated by the cavity receiver, including means to generate mechanical power and means to generate electrical power from the means to generate mechanical power.

Energy Technology Data Exchange (ETDEWEB)

The conception of a solar receiver intended to equip a tower power-station has to combine multiple requirements: very highly concentrated solar flux, unsteady in time and space; necessity to obtain a high efficiency; respect of the physical limits of the materials and of the fluid. The description of Themis solar receiver and of its operation is preceded by considerations which have led to the choice of the cavity, of the fluid and of its circulation.

Science.gov (United States)

Two patients receiving maintenance dialysis therapy developed osteonecrosis, the first in the humeral head and the second in the talus. Both patients lacked known risk factors for developing osteonecrosis. A possible pathogenic role of secondary hyperparathyroidism in this disorder is suggested. Rheumatologists evaluating patients receiving maintenance dialysis with rheumatic manifestations should be aware of this potential complication. PMID:2185360

Energy Technology Data Exchange (ETDEWEB)

The mainly instationary operation of a solar heated receiver can be simulated with sufficient accuracy only if data about the dynamic behavior are available. For this reason, the dynamic behavior of a solar cavity receiver with parabolic dish collector is investigated. The development of a mathematical simulation considering heat transfer and storage processes is presented and the procedure for a numerical solution is illustrated. The performance of the calculation method is finally demonstrated by simulating the passage of a cloud.

International Nuclear Information System (INIS)

A survey to determine the annual genetically significant dose and mean bone-marrow dose to the Australian population from radiological procedures has been undertaken. For diagnostic radiology the following were carried out: determination of the frequency of a procedure; measurement of patient doses using TLD and processing of data and calculation of gonadal and bone-marrow doses.

Energy Technology Data Exchange (ETDEWEB)

We have developed a low-temperature particle detector that uses a novel quasiparticle trapping mechanism to funnel athermal phonon energy from an 80 mg Ge absorber into a 1.6 mg doped Ge thermistor via a superconducting Al film. We report on pulse height spectra obtained at 320 mK by scanning a {sup 241}Am alpha source along the device, and show that up to 20% of the energy deposited in the Ge absorber by a 5.5 MeV alpha particle interaction can be collected into a thermistor via quasiparticle trapping. We show that this device is sensitive to the position of an alpha particle interaction in the Ge absorber for interaction distances of up to 5 mm from a quasiparticle trap.

Energy Technology Data Exchange (ETDEWEB)

Properly quantified performance of a solar-thermal cavity receiver must not only account for the energy gains and losses as dictated by the First Law of thermodynamics, but it must also account for the quality of that energy. Energy quality can only be determined from the Second Law. In this paper, an equation developed for the Second-Law efficiency of a cavity receiver is presented as an evolution from the definition of available energy or ''availability'' (occasionally called exergy). The variables required are all either known or readily determined. The importance of considering the Second-Law is emphasized by a comparison of the First- and Second-Law efficiencies around an example of data collected from two receivers that were designed for different purposes, where the attempt was made to demonstrate that a Second-Law approach to quantifying the performance of a solarthermal cavity ...

Energy Technology Data Exchange (ETDEWEB)

The present paper deals with the conversion of solar energy in a gas turbine plant with a parabolic dish collector. Particular consideration is devoted to the thermodynamic and mechanical design and partload behavior of the receiver. The incident sunlight is focussed by the parabolic dish and then beamed into the cavity receiver. Here the working medium of the gas turbine flows through tubes and is heated up to the receiver outlet temperature. The task of the receiver is to transfer the radiated energy as efficiently as possible to the working medium. Furthermore the required heating surface should be small as possible i.e. optimum use must be made of the tube material with respect to its state of stress. It is shown which geometric and thermodynamic plant parameters influence these two design criteria. An optimum receiver design is presented on the basis of the results thus ...