UK PubMed Central (United Kingdom)

Interactions between presynaptic and postsynaptic cellular adhesion molecules (CAMs) drive synapse maturation during development. These trans-synaptic interactions are regulated by alternative splicing...Full Text Available

UK PubMed Central (United Kingdom)

The docking protein p130Cas is a prominent Src substrate found in focal adhesions (FAs) and is implicated in regulating critical aspects of cell motility including FA disassembly and protrusion of the...Full Text Available

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Not Available

International Science & Technology Center (ISTC)

Prevention of Radionuclide Migration from the Soil of Semipalatinsk Nuclear Test Site by Using of Interpolymer Complexes

Science.gov (United States)

Feline heartworm disease is a very different clinical entity from canine heartworm disease. In cats, the arrival and death of immature heartworms in the pulmonary arteries can cause coughing and dyspnea as early as 3 months postinfection. Adult heartworms suppress the function of pulmonary intravascular macrophages and thus reduce clinical disease in chronic feline heartworm infection. Approximately 80% of asymptomatic cats self-cure. Median survival time for symptomatic cats is 1.5 years, or 4 years if only cats living beyond the day of presentation are considered. Aberrant worm migration is more frequent than it is in dogs, and sudden death can occur with no prior clinical signs. The bacterial endosymbiont Wolbachia likely contributes to the inflammatory pathology of heartworm disease, but its role is not yet fully clear. Unfortunately, the diagnosis, treatment, and management of feline heartworm disease are far from simple. Antemortem ...

UK PubMed Central (United Kingdom)

The adhesive proteins secreted by marine mussels form a natural glue that cures rapidly to form strong and durable bonds in aqueous environments. These mussel adhesive proteins contain an unusual...Full Text Available

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... content of the environment) are significant factors affecting the useful service life of adhesive bonded plastic composite sandwich panels at 650 F ...

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... Title : Adhesive 'PED-B' for Cementing Plastics of Formula 57-40 to the Surfaces of Contruction Units,. ... Glue PED-B is not explosive. ...

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Not Available

Energy Technology Data Exchange (ETDEWEB)

This work has analyzed the key variables of indentation tip radius, contact radius, delamination radius, residual stress and superlayer/film/interlayer properties on nanoindentation measurements of adhesion. The goal to connect practical works of adhesion for very thin films to true works of adhesion has been achieved. A review of this work titled ''Interfacial toughness measurements of thin metal films,'' which has been submitted to Acta Materialia, is included.

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PMID:15922238

British Library Electronic Table of Contents (United Kingdom)

The adhesion strength of polybutylene terephthalate (PBT) on aluminum was investigated using density functional theory-based total energy calculations. Aluminum atom was connected to a PBT monomer at different orientations and total energies were calculated in order to determine the most stable orientation. The energy differences showed that the Al oriented at 180degree with the ester group of the monomer bonded strongly. Using this orientation, the PBT monomer-adhesion on aluminum surface and the aluminum atom adhesion on PBT bulk were also investigated.

British Library Electronic Table of Contents (United Kingdom)

This paper analyses Italian interregional migration flows. The approach taken is to decompose labour mobility flows into short distance and long distance migration and to model the effects of economic variables, social capital and quality of life variables, and amenity variables, on the mobility behaviour of individuals. We estimate these different types of migration flows using a negative binomial model, augmented with instruments to control for potential endogeneity issues. Our findings demonstrate that long distance migration reflects a disequilibrium model of migration whereas short distance migration largely reflects an equilibrium model of migration. As such, attempts to model interregional migration in general will be mis-specified as the simultaneously-operating underlying mobility...

British Library Electronic Table of Contents (United Kingdom)

Contents The aim of this study was a cytogenetic analysis of stallions semen to find sex chromosome aberrations and to determine if there was an association between stallion-s age and aberration frequency for the sex chromosomes. Sperm samples were collected from 22 stallions of various age from 3 to 23-years. Multicolour FISH was performed on each sample, using probes for the sex chromosomes and EGFR gene, localized on 4p12 in domestic horse. A total of 26199 sperm cells were analysed (from 1 070 to 1 532 per animal). Among the analysed cells, there were 50.318% with X chromosome, 48.543% with Y chromosome and 1.139% with aberrant chromosomes. The frequency of aberrations was: sex chromosomes nullisomy (0.466%), XY aneuploidy (0.454%), XX disomy (0.146%), YY disomy (0.041%), diploidy (0.0...

UK PubMed Central (United Kingdom)

We combine data from the Latin American Migration Project and the Mexican Migration Project to estimate models predicting the likelihood of taking of first and later trips to the United States...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The effect of flame temperature on the Moza-Austin sticking test has been evaluated by increasing the adiabatic flame temperature used to melt the pellet and make it drop. It was found that the variation of apparent contact angle with substrate temperature, for an oxidized steel substrate, was almost independent of flame temperature over the range of 1750-2500 C. However, the strength of adhesion to the substrate increased with higher flame temperature at each substrate temperature. The adhesion force of a drop frozen on the substrate at constant temperature also increased with time up to about one h. This indicated that the adhesion was not caused solely by mechanical anchoring of solidified glass in the pores of the oxide layer. Reduction of the substrate temperature to lower temperatures after attachment of the drop caused lower strength of adhesion, but this was partially restored by raising the ...

UK PubMed Central (United Kingdom)

Adhesion of Spirogyra (tentatively, Spirogyra fluviatilis) cells to glass is described. The cells of an algal filament can adhere to a substrate only when they are...Full Text Available

UK PubMed Central (United Kingdom)

The mechanical properties of laminated window profiles manufactured using two types of adhesives were determined. The objective of this study is to evaluate the effects of heat treatment on some mechanical...Full Text Available

UK PubMed Central (United Kingdom)

E-cadherins belong to a family of membrane-bound, cellular adhesion proteins. Their adhesive properties mainly involve the two N-terminal extracellular domains (EC1 and EC2). The junctions between these...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Three popular imaging methods were used to carry out seismic migration from the Alberta foothills: Kirchhoff integral, reverse-time and explicit finite-difference migration methods. The imaging comparisons of reverse-time, Kirchhoff and f-x post-stack depth migration leads to the following conclusions. All of the three migration methods can provide acceptable and well-imaged intermediate results on the simplest model. Post-stack migration was not very sensitive to the accuracy of the velocity field once a reliable structural stack was available. With respect to the imaging accuracy and calculation cost, the Kirchhoff migration method seemed to be superior to reverse-time and f-x migration algorithms because its results on different kinds of velocity cases were basically kept coherent and consistent with the velocity model given by Mobil. ...

British Library Electronic Table of Contents (United Kingdom)

Intrinsic spherical aberrations of electron lenses have been the major resolution limiting factor in electron microscopes for several decades. While effective correctors have recently been implemented, an alternative to correct these aberrations is to circumvent them by scaling down lens dimensions by several orders of magnitude. We have fabricated electrostatic lenses exhibiting one micrometer diameter apertures and evaluated their beam forming properties against predictions from numerical ray tracing simulations. It turns out that it is routinely possible to shape a paraxial low-energy electron beam by such micron-sized lenses. Beam profiles have been measured both at a distant detector as well as in a plane close to the lens. It is shown that the lens can form a parallel beam extending ...

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PMID:17710912

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

Migration-based methods have been recently proposed to improve the estimation of angle-dependent reflectivity in the presence of complex structures. An anisotropic prestack reverse-time migration is developed to estimate the reflectivity as function of the local illumination angle. This migration method generates four simultaneous images which corresponds to the in-depth (local) plane-wave response for PP, PS, SP and SS reflections, and can be used in a Zoeppritz-based elastic inversion scheme. (author)

UK PubMed Central (United Kingdom)

An ultrasmall spot size scanning laser ophthalmoscope has been developed that employs an annular aberration-corrected incident beam to increase the effective numerical aperture of the eye thereby reducing...Full Text Available

UK PubMed Central (United Kingdom)

Chronic pain patients who show aberrant drug-related behavior often are discontinued from treatment when they are noncompliant with their use of opioids for pain. The purpose of this study was...Full Text Available

UK PubMed Central (United Kingdom)

Poland's anomaly is an uncommon congenital aberration of the chest wall characterized by absence of the pectoralis major muscle and other nearby musculoskeletal components. In this series, a wide spectrum...Full Text Available

UK PubMed Central (United Kingdom)

The inflammatory process has direct effects on normal and abnormal wound healing. Hypertrophic scar formation is an aberrant form of wound healing and is an indication of an exaggerated function of...Full Text Available

UK PubMed Central (United Kingdom)

Purpose of reviewSevere congenital neutropenia (SCN) is a primary immunodeficiency in which lack of neutrophils causes inadequate innate immune host response to bacterial...Full Text Available

UK PubMed Central (United Kingdom)

A number of aberrant morphological phenotypes were noted during propagation of the Arabidopsis thaliana DNA hypomethylation mutant, ddm1, by repeated self-pollination. Onset of a spectrum of morphological...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCentrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation...Full Text Available

Environmental Research Database

ObjectivesFirst comprehensive evaluation of the mechanical properties of an epoxy adhesive in different environments using a nano-indenter. ~%~~%~Use AFM/SEM and finite element modelling to generate knowledge of the precise mechanism of indentation in the epoxy adhesive. ~%~~%~Develop an improved data reduction algorithm for generating meaningful mechanical property data from indentation tests for adhesive materials.~%~ ~%~Validate the nano-indentation method of generating mechanical property data against [continued...]DescriptionThis project aims to address the problem of insufficient data on adhesive materials for effective modelling of joint behaviour in different environments. The methodology to be used is based on depth sensing indentation tests at different loads and rates and in different environments. Post-indentation deformation and recovery will be monitored ...

International Nuclear Information System (INIS)

The advent of aberration correction for electron microscope lenses has produced a significant advance in the improvement of resolution in microscopy. This improvement, while significant in itself, promises to have its most profound impact in materials science when it delivers quantitative information to challenge models and modellers. This capability for an electron microscope-modelling synergy to deliver useful results at the atomic level is not yet firmly established. For this reason, one of the major challenges for electron microscopy in materials science over this decade is to study systems where electron microscopists and modellers can work collaboratively. This paper explores some examples.

Energy Technology Data Exchange (ETDEWEB)

Electron energy loss (EEL) spectroscopy and high angle annular dark field (HAADF) imaging in aberration-corrected electron microscopes are powerful techniques to determine the chemical composition and structure of materials at atomic resolution. We have implemented Smart Acquisition, a flexible system of scanning transmission electron microsocpy (STEM) beam position control and EELS collection, on two aberration-corrected dedicated cold field emission gun (FEG) STEMs located at SuperSTEM, Daresbury Laboratory. This allows the collection of EEL spectra from spatially defined areas with a much lower electron dose possible than existing techniques such as spectrum imaging.

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VSP reverse-time migration is a well adaptable wave equation migration method. Its control equation not only describes all-direction propagation of seismic wave but also removes interbed multiples. Clearbout's image principle is generalized to determine image conditions, real VSP data are used to determine boundary condition, and two way reflection-free wave equation is solved by making reverse-time extrapolation. In each step of extrapolation, the migration value at relevant image point is obtained by using the image condition. The complete migration of a seismic section is achieved when reverse-time extrapolation reaches the minimum image time. In this paper it is proved theoretically and practically that this method is applicable to any velocity variation and makes the migrated section have both good resolution and high S/N ratio. Besides, this method results in high ...

Science.gov (United States)

A rapidly hydrated sorbent for moderate-temperature dry flue gas desulfurization was prepared by rapidly hydrating adhesive carrier particles and lime. The circulation ash from a circulating fluidized bed boiler and chain boiler ash, both of which have rough surfaces with large specific surface areas and specific pore volumes, can improve the adhesion, abrasion resistance, and desulfurization characteristics of rapidly hydrated sorbent when used as the adhesive carrier particles. The adhesion ability of sorbent made from circulation ash is 67.4% higher than that of the existing rapidly hydrated sorbent made from fly ash, the abrasion ratio is 76.2% lower, and desulfurization ability is 14.1% higher. For sorbent made from chain boiler ash, the adhesion ability is increased by 74.7%, the desulfurization ability is increased by 30.3%, and abrasion ratio is decreased by 52.4%. The ...

British Library Electronic Table of Contents (United Kingdom)

The present study describes the screening of five lactic acid bacteria (LAB) for use as probiotics based on their competitive adhesion and production of antagonistic substances against some fish pathogens. A reduction of adhesion of all pathogenic strains tested was obtained with three of the LAB strains (Lactococcus lactis subsp. lactis CLFP100, Lactococcus lactis subsp. cremoris CLFP102 and Lactobacillus curvatus CLFP150). With the exception of fish pathogens Flavobacterium psychrophilum and Renibacterium salmoninarum that were not inhibited by LAB strains, production of antagonistic compounds by all tested LAB was observed against at least one of the indicator strains. Based on mucus adhesion, competitive exclusion, and suppression of fish pathogen growth, the selected LAB strains can b...

UK PubMed Central (United Kingdom)

Cells of the mononuclear phagocyte lineage have the capability to adhere to and fuse with each other and to differentiate into osteoclasts and giant cells. To investigate the macrophage adhesion/fusion...Full Text Available

International Nuclear Information System (INIS)

This paper reports on a series of experiments performed to examine the ability of ion beam assisted thermal deposition to produce good adhesion of Au metallization on GaAs left-angle 100 right-angle substrates. A study of the influence of Ar ion-assisted thermal deposition of the Au films as well as in situ pre-sputtering of the GaAs surface with low-energy Ar ions prior to thermal deposition, shows that strong adhesion can be achieved without resorting to chemical cleaning. The substrate temperature and the relative flux of Ar ions to incident Au atoms were varied in order to correlate these parameters with film adhesion. The interfaces of films processed under these various conditions were examined by XTEM, RBS and XPS. Orientation texture was studied by x-ray diffraction (XRD).

Energy Technology Data Exchange (ETDEWEB)

VSP data are usually recorded in common-shot gather and contain less informations. It is difficult, therefore, to obtain good migration result by using conventional migration methods. Both inner interface reflections and interformational multiples can be removed by reverse-time migration with the use of two-way nonreflection wave equation: besides, boundary reflection in VSP can be eliminated using Clayton's absorption boundary condition. It is proved that reverse-time migration is able to improve migration quality. The imaging condition is still obtained by generalizing Claerbout's imaging principle and solving eikonal equation. This is a very practical wave equation migration method. This method is applicable to prestack VSP data, conventional multiple-offset shot gather and the simultaneous migration of VSP data and ...

UK PubMed Central (United Kingdom)

ObjectiveAlthough endoscopic procedures for lumbar disc diseases have improved greatly, the postoperative outcomes for high grade inferior migrated discs are not satisfactory. Because...Full Text Available

International Nuclear Information System (INIS)

In view of the interest in the use of gamma irradiation to extend the storage life of pre-packaged foods a report is made on the effects of gamma radiation on the migration of Irganox 1076 and Irganox 1010, antioxidants present in food packaging plastics, into synthetic triglyceride fatty-food simulant HB307 and iso-octane. The extent of migration was assayed by h.p.l.c. techniques. Migration into HB307 and iso-octane decreased steadily as irradiation progressed suggesting that gamma irradiation of packaging materials helps to prevent the contamination of food by antioxidants in the packaging. (U.K.).

Science.gov (United States)

Intrinsic spherical aberrations of electron lenses have been the major resolution limiting factor in electron microscopes for several decades. While effective correctors have recently been implemented, an alternative to correct these aberrations is to circumvent them by scaling down lens dimensions by several orders of magnitude. We have fabricated electrostatic lenses exhibiting one micrometer diameter apertures and evaluated their beam forming properties against predictions from numerical ray tracing simulations. It turns out that it is routinely possible to shape a paraxial low-energy electron beam by such micron-sized lenses. Beam profiles have been measured both at a distant detector as well as in a plane close to the lens. It is shown that the lens can form a parallel beam extending no more than 800 nm from the optical axes at a distance of 200 microm beyond the lens exit. We believe that these findings constitute a prerequisite to derive ...

Energy Technology Data Exchange (ETDEWEB)

The present conference on lens design encompasses physical and geometrical optics, diffractive optics, the optimization of optical design, software packages, ray tracing, the use of artificial intelligence, the achromatization of materials, zoom optics, microoptics and GRIN lenses, and IR lens design. Specific issues addressed include diffraction-performance calculations in lens design, the optimization of the optical transfer function, a rank-down method for automatic lens design, applications of quadric surfaces, the correction of aberrations by using HOEs in UV and visible imaging systems, and an all-refractive telescope for intersatellite communications. Also addressed are automation techniques for optics manufacturing, all-reflective phased-array imaging telescopes, the thermal aberration analysis of a Nd:YAG laser, the analysis of illumination systems, athermalized FLIR optics, and the design of array systems using shared symmetry.

Science.gov (United States)

Migration of protoplanets inside an accretion disc of a forming star is the most probable scenario for planetary system formation according to current models. Unsolved problems exist, concerning migration times and mechanisms. We report here the results of a 2D hydrodynamic study within an SPH scheme, analysing migration of an Earth-like or a Jupiter-like planet inside an inviscid sub-Keplerian accretion disc, as a function of the initial specific angular momentum of the infalling accretion disc matter. Particle capture by the protoplanet causes a rapid migration, within a few orbits, for the Earth like planet, and about 104 orbits for the Jupiter like planets. The effect of a planet pseudo-atmosphere is also discussed.

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A theoretical background of crosshole reflection imaging with pre stack, multi-mode reverse time migration has been investigated. The crosshole migration has been carried out by solving two-way scalar wave equation with finite difference approximation. The wave field extrapolation was performed backward in time, with the imaging condition applied at each extrapolation time step to create partial image of the reflector. The complete migrated image was obtained by adding all the partial images from each time step. With multi-component crosshole data available, it is possible to separate the recorded data into primary P- and S-wave field. Separating wave field before migration is helpful in enhancing migrated image quality since only one wave mode can be dealt at a time with the scalar wave equation. It is possible to migrate mixed-mode primary reflections(P-S and ...

Energy Technology Data Exchange (ETDEWEB)

Underground injection, compared to other waste disposal methods, is considered to have the advantages of isolating wastes in a confined brine aquifer well below the horizon of human activity and underground sources of drinking water (USDWs). While most of injected wastes move laterally in the injection zone, posing a long-term concern to the human health and environment, a small amount can migrate upward to the upper aquifers, causing a greater threat to the quality of USDWs. Both the dual porosity and the single porosity models were used to investigate the migration of injected wastes through these hydrologic conduits. The results indicate that regional upward migration through an extensive confining formation is a slow process. Nevertheless, injected wastes can move upward rapidly through microannuli and channels in the cement sheath and spread over a distance in the upper aquifer. The wastes can also ...

International Nuclear Information System (INIS)

In the heat exchangers of power plants, scale deposition may occur, especially at the leading edge of contraction. The growth of scale can lead to an increase in pressure and cause oscillation of the water level. In our previous study, the dependence of flow on contraction geometry was analyzed numerically and empirically. It was shown that the contraction ratio of hydraulic diameter of the flow path contributed greatly to the difference in pressure drop and turbulent kinetic energy at the leading edge of the flow path. In this study, the effect of contraction geometry and flow rate on scale adhesion was studied in AVT chemistry at 270degC using a high-velocity scale-adhesion test loop. The differential pressure and the amount of scale deposited due to scale adhesion at the leading edge of the flow path increased more in a quatrefoil-type flow path than in drill-type flow path. The differential pressure and the amount of ...

International Nuclear Information System (INIS)

Low molecular weight epoxy resin based on diglycidyl ether of bisphenol A was synthesized and mixed at constant percentages with natural rubber. The rubber epoxy system was cured with various types of curing agents such as ethylene diamine, maleic anhydride as well as the prepared resole phenol formaldehyde. A study of the photo-induced crosslinking of the prepared elastic adhesives and film samples was carried out by exposure to ultraviolet lamp (300 w) for 2 weeks at 20 deg. C. Samples containing ethylene diamine were cured at 25 + - 1 deg. C. for 24 h while samples containing maleic anhydride or resole phenol formaldehyde resins were thermally cured at 150-170 deg. C. for 10 min. Cured adhesive compositions were tested mechanically and physically and evaluated as wood adhesives. While hardness, chemical resistance as well as heat stability of the prepared cured film sample were investigated. The obtained data indicate ...

International Nuclear Information System (INIS)

A general expression for the current-density distribution of a focused-ion beam (FIB) in the chromatic-aberration region is set up in the form of a definite integral. With the experimentally obtained ion-energy distribution of a liquid-metal ion source, its contribution to the FIB current-density distribution is estimated. Calculated results explain the wide-exponential tail of a FIB.

Energy Technology Data Exchange (ETDEWEB)

Development of a number of original 3-D migration methods and algorithms is described. The computational efficiency of these algorithms is demonstrated by implementing them on vector and parallel supercomputers. Two-dimensional post-stack and pre-stack depth migration algorithms in the frequency - space domain using implicit finite difference method were also developed and implemented on a parallel computer, and adapted for applications that range from deep crustal imaging of seismic wavefields that involve wide ranging travel times and frequencies. All implicit finite difference migration algorithms were highly prallelized . The one pass 3-D post-stack depth migration algorithm was extensively used for imaging of seismic monitoring data from Cold Lake, Alberta. Experience shows that it provides the right trade-off between accuracy and computational efficiency. A new formulation of the 3-D reverse-time ...

Energy Technology Data Exchange (ETDEWEB)

The microstructure of the interphase in semicrystalline polymer matrix composites has a dramatic influence on their mechanical properties. Studies have been performed to alter this region and to correlate various interphase morphologies with changes in fiber-matrix adhesion. A reinforced nylon 66 composite, when subjected to specific thermal histories, contains an interphase composed of transcrystallinity. This region has been altered by coating fibers with a diluent, poly(vinyl pyrrolidone), and/or adding the diluent to the matrix material in very small quantities. Interphase morphology was investigated with optical microscopy, and adhesion was measured using a modified fiber pull-out test. It was found that transcrystallinity increases the interfacial shear strength. The effect different interphase morphologies have on the durability of bulk composite samples is currently under investigation.

International Nuclear Information System (INIS)

One of the key issues in safety assessment of high-level nuclear waste disposal is evaluating the effects of uncertainty inherent in radionuclide migration parameter values. In this paper, radionuclide transport parameter values and error variances (uncertainties) from in-situ tracer experiments, carried out in a single fracture at the Aespoe Hard Rock Laboratory (HRL) in Sweden, are identified by solving the inverse problem in a framework of the maximum likelihood theory. From the results, it is found that the parameter value uncertainty caused by a conceptual model of radionuclide migration is greater than that caused by a fluctuation in the observed breakthrough curve data. (author)

UK PubMed Central (United Kingdom)

Cultures of chick skin fibroblasts were dissolved in solutions of sodium dodecyl sulphate, and their entire protein content was examined by gel electrophoresis. The most abundant species migrated in...Full Text Available

Science.gov (United States)

... that range from relatively low frequency strong ground motion modeling [Vidale et al., 1985] to high frequency reverse time migration of seismic ...

International Nuclear Information System (INIS)

(Dec 1973). United Kingdom Figge, K. Unilever Forschungs-GmbH,

Science.gov (United States)

into the SiC interface to form of palladium silicides (PdSix) and the subsequent migration of elemental silicon to the surface from the SiC. Palladium silicides are ...

UK PubMed Central (United Kingdom)

Receptor protein tyrosine phosphatase T (PTPRT/PTPρ) is frequently mutated in human cancers including colon, lung, gastric and skin cancers. More than half of the identified tumor-derived...Full Text Available

UK PubMed Central (United Kingdom)

Peri-prosthetic infections are notoriously difficult to treat as the biomaterial implant is ideal for bacterial adhesion and biofilm formation, resulting in decreased antibiotic sensitivity....Full Text Available

UK PubMed Central (United Kingdom)

Adhesive tape is often used to help athletes recover from ligament sprains of the ankle or to prevent further injury. The choice of taping technique or material is often decided by personal preference,...Full Text Available

UK PubMed Central (United Kingdom)

The development of three-dimensional (3D) biomimetic scaffolds which provide an optimal environment for cells adhesion, proliferation and differentiation, and guide new tissue formation has...Full Text Available

UK PubMed Central (United Kingdom)

The kinetic parameters of single bonds between neural cell adhesion molecules were determined from atomic force microscope measurements of the forced dissociation of the homophilic protein-protein bonds....Full Text Available

UK PubMed Central (United Kingdom)

In the body, vascular cells continuously interact with tissues that possess nanostructured surface features due to the presence of proteins (such as collagen and elastin) embedded in the vascular wall....Full Text Available

UK PubMed Central (United Kingdom)

Plant surfaces covered with crystalline epicuticular waxes are known to be anti-adhesive, hardly wettable and preventing insect attachment. But there are insects that are capable of gluing their eggs...Full Text Available

UK PubMed Central (United Kingdom)

The opportunistic pathogenic yeast Candida albicans exhibits growth phase-dependent changes in cell surface hydrophobicity, which has been correlated with adhesion to host tissues....Full Text Available

UK PubMed Central (United Kingdom)

INTRODUCTIONCutiplast (absorbent perforated dressing with adhesive border; Smith & Nephew) is commonly used following orthopaedic operation, but complications of its use...Full Text Available

UK PubMed Central (United Kingdom)

The covered self-expandable metallic stent (SEMS) has been developed to overcome the problem of tissue in­growth, However, stent migration is a well-known com­­plication of covered...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Elastic depth imaging of both P-wave and S-wave prestack seismic reflection data is formulated as a degraded form of Kirchhoff migration known as Wavepath Migration (WM). Applications to the SEG/EAGE salt model show that the method is sufficiently versatile anti relaitively inexpensive. It handles S-wave data with at least the same accuracy as Pwave data when local mode conversions are removed. WM also provides an understanding of multi-mode illumination.

International Nuclear Information System (INIS)

Using ab initio (SCF/6-31G) method, mechanisms of proton migrations in methaboric acid dimers have studied. It is shown that in all the dimers considered a cooperative transfer of protons occurs. The calculated values of activation barriers of cooperative proton transfer reactions in the dimers are equal to 28.6 kcal/mol.

Energy Technology Data Exchange (ETDEWEB)

3-D depth migration is one of the most active areas of research and development and it has been approached from different angles. An accurate algorithm which works in the space-frequency domain was introduced by Blacquiere et al. (1989). Unfortunately, it is computationally very expensive and not suitable for solving real-life 3-D migration problems. This led to the development of an alternative scheme (hale, 1990) which sacrifices some accuracy but is much more efficient. It is commonly referred to as the Hale-McClellan method. An alternative procedure known as reverse-time migration works in the space-time domain. It is based on the full wave equation and yields by far the most accurate results, but it requires extremely large computer resources. However, a series of new developments (Mufti et al, 1996) have made this algorithm a very practical tool even for migrating large exploration-scale 3-D real ...

Energy Technology Data Exchange (ETDEWEB)

It has recently been found that many buildings in Taiwan were constructed with radioactively contaminated rebar, which raised great concern among the residents as well as governmental officials. In order to investigate the possible cytogenetic damage to the residents of contaminated buildings, a G-banding method was carried out on the lymphocytes of 30 radiation-exposed individuals from four families and one office building, as well as 15 control individuals from laboratory personnel. The estimated cumulative radiation doses for the exposed people range from 19.63 to 280.50 mSv. Altogether, 13 females and 17 males belonging to the radiation-exposed group, and 7 females and 8 males in the control group, were included in this study. With the exception of one sample, at least 500 metaphase spreads were scored and analyzed for each individual. All the recognizable structural aberrations of chromosomes or chromatids were recorded and statistically analyzed. Comparison ...

Energy Technology Data Exchange (ETDEWEB)

TiO{sub 2} is a vital material in several technologies including, photocatalysis, gas sensing, biomaterials and optical coatings. Among the several crystal structures of this oxide, rutile has the highest density and microhardness, the highest index of refraction and the highest temperature stability. The processing of dense polycrystalline materials often includes the addition of a liquid-forming phase at higher temperatures. This technique is known as liquid-phase sintering and has been studied extensively. Rutile boundaries containing an amorphous phase have been used to study boundary migration and grain-boundary grooving. Visible-light (VLM), scanning electron (SEM) and transmission electron microscopy (TEM) in addition to electron-backscatter diffraction (EBSD) and a focused-ion beam (FIB) tool were used to characterize boundary migration in rutile. EBSD analysis was carried out on a Philips XL30 FEG SEM equipped with a DigiView 1612 ...

Energy Technology Data Exchange (ETDEWEB)

A first-order one-way wave system has been created based on characteristic analysis of the acoustic wave system and optimization of the dispersion relation. The authors demonstrate that this system is equivalent to a third-order scalar partial-differential equation which, for a homogeneous medium, reduces to a form similar to the 45{degree} paraxial wave equation. This system describes accurately waves propagating in a 2D heterogeneous medium at angles up to 75{degree}. The one-way wave system representing downgoing waves is used for a modified reverse time migration method. As a wavefield extrapolator in migration, the downgoing wave system propagates the reflection events backwards to their reflectors without scattering at the discontinuities in the velocity model. Hence, images with amplitudes proportional to reflectivity can be obtained from this migration technique. They present examples of the application of the new ...

International Nuclear Information System (INIS)

The release rate of a nuclide from a reactor or a radioactive waste disposal plant at the accident is not steady, but varies with time. The various parameters of a nuclide migration into environment vary also day after day, or with the seasons. In such cases, dynamic behavior of the nuclide in the environment must be taken into consideration. It is difficult for a mathematical model to involve all of mechanisms for the nuclide migration. The environment for evaluation of doses are usually divided into some of compartments in which a nuclide concentration is uniform. Time variations of the nuclide concentration in the compartment are described in simultaneous differential equations. The nuclide concentration can be solved as a time function, and the radiation doses, therefore, can be estimated as a time function. Generic analysis code for dynamic compartment model (GACOM) is developed for the nuclide migration and the ...

International Nuclear Information System (INIS)

The basic approach to radioactive labeling techniques in hemoglobin identification consists of mixing 14C labeled normal carrier globin with 3H labeled unknown globin and carrying out the subsequent separations and purifications looking at the distribution of 3H and 14C radioactivity. This technique was devised to ascertain the amino acid substitution in Hb Indianapolis and was instrumental in solving the structure of Hb Vicksburg. It was also useful in determining the purity of gamma-chains from cultures of human and baboon erythroid progenitors. Another use of this technique would be in identifying aberrant peaks of radioactivity in chain separation chromatograms, such as ''pre-peaks''.

Science.gov (United States)

We have developed a novel laser ray-tracing method to measure aberrations in optical systems. It consists of delivering narrow laser pencils (by a laser scanner), recording the spots that are formed on the image plane (with a CCD camera), and computing the position of each centroid. This approach could be considered an experimental (approximate) implementation of standard numerical ray tracing. Several tests and experiments, including a direct comparison with a Hartmann-Shack wave-front sensor, provided highly satisfactory results that confirmed the validity of the method and revealed potential advantages. PMID:18073906

International Nuclear Information System (INIS)

Calibration-Free Laser-Induced Breakdown Spectroscopy (CF-LIBS) has been proposed several years ago as an approach for quantitative analysis of Laser-Induced Breakdown Spectroscopy spectra. Recently developed refinement of the spectral processing method is described in the present work. Accurate quantitative results have been demonstrated for several metallic alloys. However, the degree of accuracy that can be achieved with Calibration-Free Laser-Induced Breakdown Spectroscopy analysis of generic samples still needs to be thoroughly investigated. The authors have undertaken a systematic study of errors and biasing factors affecting the calculation in the Calibration-Free Laser-Induced Breakdown Spectroscopy spectra processing. These factors may be classified in three main groups: 1) experimental aberrations (intensity fluctuations and inaccuracy in the correction for spectral efficiency of a detection system), 2) inaccuracy in theoretical parameters used for ...

Energy Technology Data Exchange (ETDEWEB)

A wavelet transformation is performed over each of the spatial coordinates of the scalar wave equation. This transformed equation is solved directly with a finite-difference scheme for both homogeneous and smooth inhomogeneous media. Wavefield extrapolation is performed completely in the spatial wavelet domain without transforming back into the space domain at each time step. The wavelet coefficients are extrapolated, rather than the wavefield itself. The numerical solution of the scalar wave equation in the spatial wavelet domain is closely related to the finite-difference method because of the compact support of the wavelet bases. Poststack reverse-time migration is implemented as an application. The resolution spaces of the wavelet transform provide a natural framework for multigrid analysis. Migrated images are constructed from various resolution spaces.

International Nuclear Information System (INIS)

The variation of surface composition and sintering of the binary Pd_7Ag_3 nanoparticles prepared by chemical reduction were studied. The composition of the as-prepared Pd_7Ag_3 nanoparticles across the diameter is inhomogeneous due to different reduction potentials of Pd and Ag. Upon heating, Ag will migrate to the surface because of its lower surface energy. Surface modification results in variation of surface composition during the sintering process. Stearic acid acts as a grain growth inhibitor. The migration of Ag to the surface is suppressed and the sintering is retarded. Modification by polyethylene glycol leads to more migration of Ag atoms from the core to the surface. This makes the nanoparticles easier to sinter.

CERN Document Server

The Ludwig-Soret effect, the migration of a species due to a temperature gradient, has been extensively studied without a complete picture of its cause emerging. Here we investigate the dynamics of DNA and spherical particles sub jected to a thermal gradient using a combination of Brownian dynamics and the lattice Boltzmann method. We observe that the DNA molecules will migrate to colder regions of the channel, an observation also made in the experiments of Duhr, et al[1]. In fact, the thermal diffusion coefficient found agrees quantitatively with the experimental value. We also observe that the thermal diffusion coefficient decreases as the radius of the studied spherical particles increases. Furthermore, we observe that the thermal fluctuations-fluid momentum flux coupling induces a gradient in the stress which leads to thermal migration in both systems.

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Polyethylene pipes and connections are being widely used in treated water distribution services. Migration of low molecular weight compounds from the polyethylene into the water can change its final quality. This paper is about the concentrations and identification of the migration compounds found in treated water after staying in contact with low and high-density polyethylene. Identification and quantification were carried out using CLSA (Closed Loop Stripping Analysis) extraction technique and gas chromatography coupled to mass spectrometry (HRGC/HRMS). (Author) 12 refs.

Science.gov (United States)

An improved method of generating angle-domain common-image gathers (ADCIGs) by VSP reverse time migration (RTM) is introduced in this paper. The formula which is used to compute the receiver wavefield for VSP RTM is modified by adding an amplitude correction term in order to conveniently output amplitude-preserved ADCIGs. Compared with the surface seismic data, VSP data contains much richer wavefields. However, the direct and downgoing waves can bring about serious imaging artifacts in ADCIGs, especially the direct wave. The feasibility and validity of this method is demonstrated by both numerical and real VSP data from western China. Thus, the ADCIGs from this method can provide reliable basic data for VSP migration velocity analysis, VSP AVO/AVA analysis, and inversion.

International Nuclear Information System (INIS)

We report a new method of generating nano and micro patterns using focused ion beam (FIB) induced adhesion. The method utilizes selective irradiation of thin metallic films grown on substrates by focused ion beam followed by peel off. After peel off of the irradiated thin film it is observed that the ion beam scanned portions are retained on the substrate, creating nano and micro patterns. The method is suitable for materials of which the adhesion to the substrate can be improved by ion bombardment. The phenomenon has been demonstrated by creating gold nano patterns of different shapes and sizes ranging from 500 nm to 5 #mu#m on SiO_2-Si substrate using 10-30 keV Ga FIB at beam currents up to 10 pA. The mechanism involved in the process has been discussed. The technique could be utilized to prepare micro and nano patterns of thin films deposited on an appropriate substrate for optical, plasmonic and sensor related applications.

International Nuclear Information System (INIS)

A method was proposed and examined to deposit thick cubic boron nitride (cBN)-rich layer of good adhesion to silicon substrate. The method combined (i) the insertion of a thick sp"2 buffer layer, and (ii) the use of an appropriate assist ion beam energy for the growth of the cBN-rich top layer. The sp"2-bonded boron nitride buffer layer was deposited under irradiation of ions with energies in the range of 200-360 eV. The buffer layer was found to contain curled graphitic basal planes, and so was supposed to be relatively deformable, and facilitate the relaxation of stresses in the cBN-rich top layer. The ion assist introduced during the growth of the cBN-rich layer was supposed to both create and annihilate defects, and so resulted in the generation and relaxation of internal stresses. Results showed that the insertion of a 492 nm sp"2 buffer layer, and the use of a beam energy of 450 eV for assisting the growth of the top layer can produce a 643-nm-thick cBN-rich ...

Science.gov (United States)

This study investigated the effect of board type (unmodified vs. MAPE modified) on the surface quality and thickness swelling-water absorption properties of recycled high density polyethylene (HDPE) based wood plastic composites. Additionally, two commercially available coatings (cellulosic coating and polyurethane lacquer coating) were also applied to composite surfaces and their adhesion strength, abrasion and scratch resistance, and gloss values were determined. This study showed that modification of the composites with MAPE coupling agent increased the surface smoothness and reduced the water absorption and thickness swelling of the panels. Abrasion resistance of the composites was also improved through MAPE modification. Regardless of board type, higher scratch resistance and gloss values were observed for polyurethane lacquer coated samples compared to those of cellulosic varnish coated ones. Improvement of adhesion strength was also seen ...

British Library Electronic Table of Contents (United Kingdom)

For a soft-contact-lens (SCL) wearer, corneal health and comfort are strongly influenced by water transport through the polymeric materials used in lens fabrication. In particular, evaporative water loss at the anterior lens surface is a potential cause of contact-lens dehydration and of post-lens tear-film depletion, which in turn, may lead to discomfort, dryness syndrome, and/or lens adhesion.We present a solution-diffusion model for transport of water through soft-contact-lens materials to mimic evaporative dehydration from a contact lens during blinking and to access possible SCL adhesion to the corneal surface under a variety of environmental conditions (e.g., wind speed and relative humidity). To describe the water-transport process, we use an extended version of the Maxwell-Stefan m...

British Library Electronic Table of Contents (United Kingdom)

This paper presents a new method of extracting biologic particles from a mixture of particles. The method is based on the pumping effect in a p-shaped ultrasonic actuator, which has a gap between its two vibrating metal plates. An adhesive tape is placed at a proper position in the gap. Due to the pumping effect which is induced by the sound field in the gap, the particles with smaller mass and radius in the mixture can be pumped up to reach the adhesive tape; while the ones with larger mass cannot. Therefore, the particles with smaller mass and radius can be extracted from the mixture. A theoretical model which can well explain the operation principle and experimental phenomena is developed. By the experimental results and the theoretical analyses based on the model, the validity of the m...

British Library Electronic Table of Contents (United Kingdom)

The colonization of an implant surface by bacteria is an extremely important medical problem, which often leads to the failure of medical devices. Modern surface modification techniques, such as ion implantation, can confer to the surfaces very different properties from those of the bulk underlying material. In this work, austenitic stainless steel 316 LVM has been superficially modified by Si^+ ion implantation. The effect of surface modification on the biocompatibility and bacterial adhesion to 316 LVM stainless steel has been investigated. To this aim, human mesenchymal stem cells (hMSCs), as precursor of osteoblastic cells, and bacterial strains relevant in infections related to orthopedic implants, i.e., Staphylococcus aureus and Staphylococcus epidermidis, have been assayed. For the ...

Energy Technology Data Exchange (ETDEWEB)

Iron nickel chromium manganese silicon and iron chromium nickel manganese silicon molybdenum niobium alloys have a so-called duplex structure in a wide concentration range. This causes an excellent resistance to wear superior in the case of adhesive stress with optimized concentrations of manganese, silicon, molybdenum and niobium. The materials can be used for welded armouring structures wherever cobalt and boron-containing alloy systems are not permissible, e.g. in nuclear science. Within the framework of pre-investigations for manufacturing of filling wire electrodes, cast test pieces were set up with duplex structure, and their wear behavior was examined. (orig.).

UK PubMed Central (United Kingdom)

AIM: To investigate the effects of transforming growth factor β1 (TGF-β1) on the differentiation of colonic lamina propria fibroblasts (CLPF) into myofibroblasts in vitro.METHODS:...Full Text Available

UK PubMed Central (United Kingdom)

SummaryIn vivo tumor cell migration through integrin-dependent pathways is key to the metastatic behavior of malignant cells. Using quantitative in vivo...Full Text Available

UK PubMed Central (United Kingdom)

The aim of this study was to investigate the supposed vertical diel migration and the accompanying physiology of Beggiatoa bacteria from hypersaline microbial mats. We combined microsensor,...Full Text Available

CERN Document Server

We present analytic and numerical results which illustrate the effects of Jupiter's accretion of nebular gas and the planet's radial migration on its Trojan companions. Initially, we approximate the system by the planar circular restricted three-body problem and assume small Trojan libration amplitudes. Employing an adiabatic invariant calculation, we show that Jupiter's thirty-fold growth from a $10 M_\\oplus$ core to its present mass causes the libration amplitudes of Trojan asteroids to shrink by a factor of about 2.5 to $\\sim 40%$ of their original size. The calculation also shows that Jupiter's radial migration has comparatively little effect on the Trojans; inward migration from 6.2 to 5.2 AU causes an increase in Trojan libration amplitudes of $\\sim4%$. In each case, the area enclosed by small tadpole orbits, if made dimensionless by using Jupiter's semimajor axis, is approximately conserved. Similar adiabatic ...

UK PubMed Central (United Kingdom)

In addition to regulating acid secretion, the gastric antral hormone gastrin regulates several important cellular processes in the gastric epithelium including proliferation, apoptosis, migration, invasion,...Full Text Available

UK PubMed Central (United Kingdom)

Deficient wound healing in diabetic patients is very frequent, but the cellular and molecular causes are poorly defined. In this study, we evaluate the hypothesis that high glucose concentrations inhibit...Full Text Available

UK PubMed Central (United Kingdom)

The destiny of the mitotically active cells of the subventricular zone (SVZ) in adult rodents is to migrate to the olfactory bulb, where they contribute to the replacement of granular and periglomerular...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThis paper is based on data gathered from a 2006 survey of 1,098 "street children" in Northern Tanzania. It examines the role that school may play in preventing the migration...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This report describes mathematical predictions for the migration of radionuclides from an emplaced radioactive waste container. The model assumes a spherical-equivalent waste solid surrounded by backfill but neglects the effect of decay heat. 7 refs., 2 tabs. (TEM)

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With an objective to discuss applicability of resistivity imaging using electromagnetic migration to detection of underground cavity, an applicability test was carried out on calculation of a numerical model and measurement data. By using the numerical model, a calculation was performed on a hypothetical case that a cubic cavity with sides each at 40 m exists in a homogenous medium of 200 ohm-m, with the cavity top located 20 m below the ground surface. As a result, it was possible to structure in a very short calculation time an image of the cavity which cannot be identified by one-dimensional inverse analysis. In the case of this cavity, a center of the image was structured on its lower face. It was shown that a location to indicate the image must be changed according to difference in the measurement locations. In a test on data measured in an underground cavity in the city of Utsunomiya, Tochigi Prefecture, it was found that the result may vary largely depending ...

CERN Document Server

The massive stars in the Galactic center inner arcsecond share analogous properties with the so-called Hot Jupiters. Most of these young stars have highly eccentric orbits, and were probably not formed in-situ. It has been proposed that these stars acquired their current orbits from the tidal disruption of compact massive binaries scattered toward the proximity of the central supermassive black hole. Assuming a binary star formed in a thin gaseous disk beyond 0.1 pc from the central object, we investigate the relevance of disk-satellite interactions to harden the binding energy of the binary, and to drive its inward migration. A massive, equal-mass binary star is found to become more tightly wound as it migrates inwards toward the central black hole. The migration timescale is very similar to that of a single-star satellite of the same mass. The binary's hardening is caused by the formation of spiral tails lagging the stars ...

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This document outlines the major steps that must be taken by the Savannah River Site (SRS) to migrate the SRS information technology (IT) environment to the new architecture described in the Savannah River Site Computing Architecture. This document proposes an IT environment that is {open_quotes}...standards-based, data-driven, and workstation-oriented, with larger systems being utilized for the delivery of needed information to users in a client-server relationship.{close_quotes} Achieving this vision will require many substantial changes in the computing applications, systems, and supporting infrastructure at the site. This document consists of a set of roadmaps which provide explanations of the necessary changes for IT at the site and describes the milestones that must be completed to finish the migration.

International Nuclear Information System (INIS)

Field experiments were conducted in the 30-km zone of Gomel's region of the Byelorussia to study factors aecting a biological radionuclide accessibility. A contamination density by radiocesium equaled 2,7-9,9 MBk/m"2, strontium 90 - 0,3-0,5 MBk/m"2 in 1991. A sowing of oats barley, lupin was carried out. It was shown that radionuclide accumulation by agricultural plants was determined basically by biological peculiarities of plants in greater degree than by the contamination density. It was shown that strontium 90 migration from the soil was more intensive than that of radiocesium. 8 tabs.

Science.gov (United States)

The dual-media approach to contaminant transport modeling has emerged over the years as a clear improvement over the conventional Fickian advection-dispersion, or single-medium model, in an increasing number of settings. Recent application to the MADE-2 tracer test at Columbus Air Force Base has extended interest to field-scale plume migration in unconsolidated sediments. Subsequent application to tritium migration from the SRS F- and H-area seepage basins within this study also demonstrated improved transport predictions.

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VSP data are usually acquired in order to obtain high-resolution images of complex structures in reservoirs and near boreholes. The authors present an elastic iterative migration scheme which has few limitations regarding the complexity of the geology, and where the macromodel for both P- and S-wave velocities is automatically improved and updated at each iteration. They avoid wavefield separation (up/down and P/S) and the simplifying assumptions of small dips underlying most such methods. The migration scheme is based on elastic inversion theory. The wavefield extrapolation is based on a high-order, coarse-grid, finite-difference solution to the elastic two-way wave equation. At each iteration, the macromodel is updated using a gradient method, in which the gradient is computed by correlation of forward-modelled fields with back-propagated residual fields. The first iteration of the migration scheme is equivalent to ...

British Library Electronic Table of Contents (United Kingdom)

Mammalodon colliveri is an unusual toothed archaic mysticete (Cetacea) from the Upper Oligocene Jan Juc Formation of south-east Australia. The morphology of the holotype skull and postcrania are described in detail. Superimposed on the generally plesiomorphic archaeocete-like morphology of Mammalodon are subtle mysticete synapomorphies. Derived features of Mammalodon include a short and bluntly rounded rostrum, reduced premaxillae, and anterodorsally directed orbits. Within Mysticeti, this suite of features is unique. The aberrant rostral morphology of Mammalodon suggests specialization for suction feeding. Janjucetus hunderi is placed in an expanded family Mammalodontidae. Phylogenetic analysis corroborates the monophyly of Basilosauridae, Neoceti, Odontoceti, and Mysticeti, and yields a ...

British Library Electronic Table of Contents (United Kingdom)

Aberrant amyloid-b peptide (Ab) accumulation along with altered expression and function of nicotinic acetylcholine receptors (nAChRs) stand prominently in the etiology of Alzheimer's disease (AD). Since the discovery that Ab is bound to a7 nAChRs under many experimental settings, including post-mortem AD brain, much effort has been expended to understand the implications of this interaction in the disease milieu. This research update will review the current literature on the a7 nAChR-Ab interaction in vitro and in vivo, the functional consequences of this interaction from sub-cellular to cognitive levels, and discuss the implications these relationships might have for AD therapies.

British Library Electronic Table of Contents (United Kingdom)

DNA methylation is considered as a potential cause of aberrations in regulation of gene expression during carcinogenesis. Therefore, changes in DNA methylation patterns may be targets for chemoprevention. In the present study, we investigated effects of all-trans retinoic acid (ATRA), vitamin D3, and resveratrol alone and in combination with adenosine analogues: 2-chloro-2'-deoxyadenosine (2CdA) and 9-beta-d-arabinosyl-2-fluoroadenine (F-ara-A), on methylation and expression of retinoic acid receptor beta 2 (RARbeta2) in MCF-7 and MDA-MB-231 breast cancer cell lines. Alterations in methylation and expression levels after treatment of cells with the tested compounds were evaluated by methylation-sensitive restriction analysis (MSRA) and real-time PCR, respectively. RARbeta2 promoter in the ...

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PVD-coatings based on TiB{sub 2} are expected to show high wear resistance and low tendency of adhesion on metal forming tools. Coating adhesion and morphology can be modified over a wide range by varying the content of nitrogen (N{sub 2}) and the deposition parameters power and bias voltage. All coatings were deposited using commercial unbalanced magnetron equipment, the deposition was homogeneous in a volume of 400 x 400 x 400 mm{sup 3}. Hipped and hot pressed TiB{sub 2}-targets were used, nitrogen (N{sub 2}) was added as gas, Ti and Al by a solid Ti-Al-target. The tribological behaviour was tested by a pin-on-disc wear test. The coatings investigated were TiB{sub 2}, TiAlB(N), TiAl(N) and TiB{sub 2}/TiAl(N). As counterpart in the pin-on-disc wear test, 6 mm diameter spheres of steel (100Cr6), aluminium, brass and bronze were used. The experiments showed a non-uniform wear behaviour. For the combinations TiAlB(N) and TiB{sub 2} versus ...

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This Test Plan outlines the testing to be done on the Special Protective Coating (SPC) Polyurea which includes: Tank Waste Compatibility, Decontamination Factor Testing, and Adhesion Strength Testing after a sample has been exposed to Radiation.

Science.gov (United States)

The long-term durability of bonds between adhesive resins and dentin is of significant importance for the longevity of bonded restorations. We carried out an in vivo one-year study to evaluate the durability of resin-dentin bonds in the oral cavity, as well as to test the hypothesis that the adhesive interface would show morphological changes in vivo over time. Very shallow saucer-shaped dentin cavities were prepared in 12 intact teeth of one Japanese monkey (Macaca fuscata) under general anesthesia. The cavities were restored with Clearfil Liner Bond II and Clearfil Photo Posterior resin composite. The teeth were extracted at three different times: immediately, and 180 and 360 days after placement of the restorations. One day after the monkey was killed, specimens of the three time periods were subjected to the micro-tensile bond test at a crosshead speed of 1 mm/min. The surfaces of the failed bonds were observed under a field emission ...

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Genomic instability can be produced by ionising radiation, so-called radiation-induced genomic instability, and chemical mutagens. Radiation-induced genomic instability occurs in both germinal and somatic cells and also in the offspring of irradiated individuals, and it is characterised by genetic changes including chromosomal rearrangements. The majority of studies of trans-generational, radiation-induced genomic instability have been described in the male germ line, whereas the authors who have chosen the female as a model are scarce. The aim of this work is to find out the radiation-induced effects in the foetal offspring of X-ray-treated female rats and, at the same time, the possible impact of this radiation-induced genomic instability on the action of a chemical mutagen. In order to achieve both goals, the quantity and quality of chromosomal damage were analysed. In order to detect trans-generational genomic instability, a total of 4806 metaphases from foetal tissues from the ...

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The Heavy-Ion Fusion Sciences Virtual National Laboratory is pursuing an approach to target heating experiments in the Warm Dense Matter regime, using spacecharge-dominated ion beams that are simultaneously longitudinally bunched and transversely focused. Longitudinal beam compression by large factors has beendemonstrated in the Neutralized Drift Compression Experiment (NDCX) with controlledramps and forced neutralization. Using an injected 30-mA K+ ion beam with initialkinetic energy 0.3 MeV, axial compression leading to ~;;50-fold current amplification andsimultaneous radial focusing to beam radii of a few mm have led to encouraging energy deposition approaching the intensities required for eV-range target heating experiments. We discuss the status of several improvements to our Neutralized Drift Compression Experiment and associated beam diagnostics that are under development to reach the necessary higher beam intensities, including: (1) greater axial compression via a longer ...

Science.gov (United States)

A significant challenge in proteomics biomarker research is to identify the changes that are of highest diagnostic interest, among the many unspecific aberrations associated with disease burden and inflammation. In the present study liver tissue specimens (n=18) from six experimental stages were collected from the resistant hepatocyte (RH) rat model of liver cancer and analyzed by 2D DIGE. The study included triplicates of regenerating liver, control "sham-operated" liver, three distinct premalignant stages and hepatomas. Out of 81 identified proteins two-thirds were differentially abundant in rat hepatomas compared to control rat liver and, secondly, the majority of proteins were also changed in precursor stages. This underscores the importance of adequate control samples in explorative cancer biomarker research. We confirm several proteomic changes previously identified in human hepatocellular carcinoma (HCC) and we identify novel candidate proteomic ...

International Nuclear Information System (INIS)

Full text: DNA rearrangement events leading to chromosomal aberrations are central to ionizing radiation-induced cell death. Although DNA double-strand breaks are probably the lesion that initiates formation of chromosomal aberrations, little is understood about the molecular mechanisms that generate and modulate DNA rearrangement. Examination of the sequences that flank sites of DNA rearrangement may provide information regarding the processes and enzymes involved in rearrangement events. Accordingly, we developed a method using inverse PCR that allows the detection and sequencing of putative radiation-induced DNA rearrangements in defined regions of the human genome. The method can detect single copies of a rearrangement event that has occurred in a particular region of the genome and, therefore, DNA rearrangement detection does not require survival and continued multiplication of the affected cell. Ionizing radiation-induced DNA ...

International Nuclear Information System (INIS)

The synovial and bone uptake of tracer in the knees of patients with rheumatoid arthritis (RA) was quantified using "9"9Tc"m-hexamethyl propylene amine oxime-labelled leucocytes and "9"9Tc"m-methylene diphosphonate (MDP), respectively. Significant neutrophil migration and MDP uptake occurred in the knees of patients with RA irrespective of the disease duration. In all but one patient neutrophil migration was reduced after intra-articular steroid injection. The change in MDP uptake after steroid injection was variable. There was a significant correlation between the percentage reduction in neutrophil migration and pain score, while the latter correlated poorly with the change in MDP uptake. The quantification of the neutrophil component of the inflammatory process is a sensitive index for monitoring RA activity and response to pharmacological interventions, while quantitative bone scintigraphy should not be employed to ...

CERN Document Server

Current theories on planetary formation establish that giant planet formation should be contextual to their quick migration towards the central star due to the protoplanets-disc interactions on a timescale of the order of $10^5$ years, for objects of nearly 10 terrestrial masses. Such a timescale should be smaller by an order of magnitude than that of gas accretion onto the protoplanet during the hierarchical growing-up of protoplanets by collisions with other minor objects. These arguments have recently been analysed using N-body and/or fluid-dynamics codes or a mixing of them. In this work, inviscid 2D simulations are performed, using the SPH method, to study the migration of one protoplanet, to evaluate the effectiveness of the accretion disc in the protoplanet dragging towards the central star, as a function of the mass of the planet itself, of disc tangential kinematics and of the presence of a planet ``pseudo-atmosphere''. To this ...

British Library Electronic Table of Contents (United Kingdom)

Several researchers have investigated morphological changes on the south-eastern Mediterranean coast during the late Holocene. However, very few of these studies include quantitative data covering the last 200?years. In this study, topographical maps, nautical charts and aerial photographs are used to estimate the shoreline migrations and beach?nearshore sand balance over the last 200?years in Haifa Bay, Israel, the northernmost final depositional sink of the Nile littoral cell. The findings reflect two main periods. During the first period, between 1799 and 1928, human intervention along the bay?s coast was negligible, a significant coastal expansion of ?50 to 150?m (averages of 0.4?1.2?m/year) was measured, and sand accumulation was estimated at ?70,000?m3 annually in the beach?nearshore...

Science.gov (United States)

We present here a study based on the migration of protoplanets in an accretion disc of a forming star, as the mainly proposed scenario for the formation of planetary systems. Attention is here focused on the mutual interactions between two protoplanets, both embedded in the accretion disc, as a function of the protoplanets masses, their relative positions, the dynamic properties of the accretion disc particles. The study is performed through a 2D SPH code and preliminary results show an oscillation of the distance between the two protoplanets, together with a slow migration of the two planets towards the central star when two Jupiter-like planets are considered. Less correlated behaviour is observed when at least one of the two protoplanets has an Earth-like mass. The role played by the disc particles initial angular momentum is discussed.

Science.gov (United States)

We propose a new algorithm for two-dimensional magnetotelluric (MT) inversion. Our algorithm is an MT inversion based on the steepest descent method, borrowed from the backpropagation technique of seismic inversion or reverse time migration, introduced in the middle 1980s by Lailly and Tarantola. The steepest descent direction can be calculated efficiently by using the symmetry of numerical Green's function derived from a mixed finite element method proposed by Nedelec for Maxwell's equation, without calculating the Jacobian matrix explicitly. We construct three different objective functions by taking the logarithm of the complex apparent resistivity as introduced in the recent waveform inversion algorithm by Shin and Min. These objective functions can be naturally separated into amplitude inversion, phase inversion and simultaneous inversion. We demonstrate our algorithm by showing three inversion results for synthetic data.

International Nuclear Information System (INIS)

The effect on human health of using food packaging made from recycled materials will depend on whether the elements will migrate into the food itself and at which levels that would be of concern. There is no EU directive for paper and board packaging, but guidelines on paper and board intended to come into contact with food are being developed in another forum. These do not propose limits for paper intended to come into contact with dry foods. However, for other foodstuffs, restriction limits in paper of 0.002 mg/dm"2 (Cd), 0.003 mg/dm"2 (Pb), and 0.002 mg/dm"2 (Hg) have been proposed. This paper describes a radiotracer method that has been applied to the determination of migration of trace elements from paper and board into real food samples.

British Library Electronic Table of Contents (United Kingdom)

Mesopelagic zooplankton may meet their nutritional and metabolic requirements in a number of ways including consumption of sinking particles, carnivory, and vertical migration. How these feeding modes change with depth or location, however, is poorly known. We analyzed fatty acid (FA) profiles to characterize zooplankton diet and large particle (>51?m) composition in the mesopelagic zone (base of euphotic zone ?1000m) at two contrasting time-series sites in the subarctic (station K2) and subtropical (station ALOHA) Pacific Ocean. Total FA concentration was 15.5 times higher in zooplankton tissue at K2, largely due to FA storage by seasonal vertical migrators such as Neocalanus and Eucalanus. FA biomarkers specific to herbivory implied a higher plant-derived food sou...

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Ab initio planewave pseudopotential method is used to study carbon diffusion and pairing in crystalline silicon. The calculation is performed with a 40 Ry planewave cutoff and 2x2x2 special k-point sampling with a supercell of 64 atoms. It is found that substitutional carbon attracts interstitial Si forming a <001> C interstitial with a large binding energy of 1.45 eV. The interstitial carbon is mobile and can migrate with a migration energy of 0.5 eV. The interstitial carbon can bind further to another substitutional carbon forming a substitutional carbon-interstitutional carbon pair with a binding energy of 1.0 eV. This model is used to understand the effect of high C concentration on the transient enhanced diffusion in Si.

International Nuclear Information System (INIS)

Water repellency en the microstructure super-hydrophobic cured surface is important for research and industrial purposes. This microstructure film can be cured on polyethylene terephthalate PET surface by electron beam (EB) at different irradiation doses 10-100 kGy. The microstructure formulation composed from hydrophobic acrylate oligomer (EB 244) and monomer (SR 440). The irradiation induced cross linking of the prepared microstructure was proved by FTIR spectroscopy and the adhesion force by abrasion test. Some factors affecting the adhesion force of the prepared microstructure film such as oligomer/monomer composition ratio and the thickness of the microstructure cured film were studied. The contact angles (8) were measured on cured surfaces before and after adding the super hydrophobic nanoparticles (Zonyl 9361). The super-hydrophobic cured surface showed the self-cleaning property. The volume of water droplet affected both the observed ...

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Duplex-coating procedures consisting of plasma nitriding and Me-C:H hard coating lead to an improved performance of the devices because the Me-C:H coating is supported by the nitrided phase and, therefore, the `eggshell-effect` is avoided. Furthermore, this support leads to a higher load-bearing capacity of the thin film. Two standard procedures (classical high-pressure plasma nitriding and unbalanced magnetron sputtering of Ti-C:H) were performed subsequently to prepare the duplex coatings on X20Cr13 ferritic stainless steel. The corrosion resistance of the steel could be improved by nitriding at 450 C compared to the untreated ferritic substrate. The roughness is determined by the nitriding step. The weakest point of the coating is the transition zone between the nitrided and the untreated substrate and not the interface between the Ti-C:H coating and the nitrided substrate as shown by the Rockwell and scratch tests. The adhesion of the duplex structure (plasma ...

Energy Technology Data Exchange (ETDEWEB)

In this paper, we report on a series of experiments designed to study the influence of plasma nitriding on the mechanical properties of austenitic stainless steel. Plasma nitriding experiments were conducted on AISI 304L steel in a temperature range of 375-475 C using pulsed-DC plasma with different N{sub 2}-H{sub 2} gas mixtures and treatment times. Firstly the formation and the microstructure of the modified layer will be highlighted followed by the results of hardness measurement, adhesion testing, wear resistance and fatigue life tests. The modified surface was analyzed directly after plasma nitriding as well as using a depth profiling method. The microhardness after plasma nitriding is increased up to 19 GPa, that is a factor of five higher compared to the untreated material (3.3 GPa). The adhesion is examined by Rockwell indentation and scratch test. No delamination of the treated layer could be observed. The wear rate after plasma ...

Energy Technology Data Exchange (ETDEWEB)

In the region of annular liquid film-mist flow, the behavior of the droplets formed from the liquid film and the rate of formation are the subjects to be clarified in connection with the forecast of dry-out point, which becomes a problem in the region of high dryness such as reactor cooling system and steam generators. Many researches have been performed on such problem in vertical tubes, but the characteristics in horizontal flow have not yet been sufficiently clarified. This series of research is to clarify various characteristics, such as the velocity of vapor phase, the flow rate distribution of droplets, the formation and adhesion of droplets and the structure of liquid film, in the region of liquid film-mist flow, where liquid film exists on the bottom of a horizontal rectangular channel, and vapor flow is accompanied by droplets. In this study, by the measurement of the flow rate distribution of droplets on respective cross sections along channel axis, the ...

Energy Technology Data Exchange (ETDEWEB)

The properties of polycrystalline (Ti, Al)N coatings deposited on non-nitrided, classically plasma-nitrided and low pressure plasma-nitrided AISI H11 steel samples were investigated. The plasma deposition and low pressure plasma nitriding were performed in a Z700-LH magnetron sputter ion plating unit, while a separate unit was used for plasma nitriding of specimens at a pressure of several millibars. The (Ti, Al)N coating was deposited onto all the samples using the same equipment as for the plasma deposition and low pressure plasma nitriding. For the characterization of the composite structures, the following methods were used: scratch test, X-ray diffraction analysis, scanning electron microscopy, scanning tunnelling microscopy and microhardness testing. It was found that plasma nitriding prior to coating deposition strongly affects the growth and properties of hard coatings, such as the microhardness, adhesion, preferred orientation, structure and morphology. ...

International Nuclear Information System (INIS)

The present study sought a biochemical explanation for retarded brain development in the heterozygous offspring of the phenylketonuric (PKU) mother. Two rat models of simulated maternal PKU, one induced by p-chloropheylalanine and phenylalanine and the other by phenylacetate, were employed in this investigation. Maternal PKU had no influence on cerebral concentrations of DNA, protein, and cholesterol, which were normal in the 2 d old pup. However, there was a noticeable disruption of the normal ganglioside pattern and a significant reduction of sialoglycoproteins. Concomitant with a delayed drop in the gangliosides Q/sub 1b/ and D_3, was a slower rise in M_1 and D/sub 1a/. At least 66% of sialoglycoproteins located on SDS-PAGE gel chromatograms, by radioactivity incorporated in vivo from radiolabeled N-acetylmannosamine and by ("3H) sialic acid released by neuraminidase from periodate-("3H) borohydride labeled glycoproteins, have mobilites of the cell adhesion ...

Energy Technology Data Exchange (ETDEWEB)

From a macroscopic point of view, corrosion of Zn alloy coated steel sheet occurs by the coating preceding corrosion mechanism; microscopically, however, the coated layer corrosion velocity in the tip of corrosion is different. In order to find the main factors of under-film corrosion of Zn and Zn-Fe alloy coatings in the salt water spray atmospheric exposure test, the correlation between point inflation-exfoliation width and chlorine penetration behavior, point adhesion, and the difference in chlorine penetration behavior due to alloy coating components were investigated. Consequently, the following results were obtained: 1. The better correlation was observed between chlorine penetration distance and point inflation-point exfoliation width. 2. The durability of coating against chlorine penetration improved by increase in point adhesion and Zn content in the coating layer. 3. Zn-Fe (10-20%) alloy coating showed better durability against ...

International Nuclear Information System (INIS)

One of the greatest opportunities for using of biomass as a precursor in the production of polymeric materials is the lignocellulose composites that can combine high performance with low costs. This work is a initial study on the production of a lignocellulose reinforced polyethylene composite. A compatibilization made by a induced gamma radiation grafting reaction was used to increase the adhesion between the matrix and the reinforced or filled fibers. The lignocellulose materials were exposed to gamma radiation in order to promote a molecular degradation and increase its reactivity. The polymer, the lignocellulose material and the compatibilization were processed by extrusion and the composite produced by this process were characterized by mechanical tests. (author)

Energy Technology Data Exchange (ETDEWEB)

There is increasing demand to functionalize meso- and nano-porous materials by coating and make the porous substrate biocompatible or environment friendly. However, coating on a meso-porous substrate poses great challenges, especially if the pore aspect ratio is high. In the current work the pulsed laser deposition (PLD) method is used for coating Ni{sub 3}Al-based meso-porous membranes with diamond-like carbon (DLC) layers of high thickness homogeneity and adhesion. (orig.)

International Nuclear Information System (INIS)

The use of polymer matrix composites in aerospace propulsion applications is currently limited by insufficient resistance to erosion by abrasive media. Erosion resistant coatings may provide necessary protection; however, adhesion to many high temperature polymer matrix composite (PMC) materials is poor. A low pressure oxygen plasma treatment process was developed to improve adhesion of CN_x coatings to a carbon reinforced, fluorinated polymer matrix composite. Fullerene-like CN_x was selected as an erosion resistant coating for its high hardness-to-elastic modulus ratio and elastic resilience which were expected to reduce erosion from media incident at different angles (normal or glancing) relative to the surface. In situ x-ray photoelectron spectroscopy was used to evaluate the effect of the plasma treatment on surface chemistry, and electron microscopy was used to identify changes in the surface morphology of the PMC substrate after plasma ...

Energy Technology Data Exchange (ETDEWEB)

Wear-resistant TiN coatings deposited on tool steels are used frequently in industry. There is a trend towards further optimizing these coatings, e.g. by plasma nitriding the tool surface prior to TiN deposition. In this work the influence of the nitriding conditions on the surface properties of AISI 304 and ASP 23 tool steels was investigated. The plasma nitriding was carried out in a triode ion plating configuration normally used to deposit TiN coatings. At the surface of AISI 304 stainless steel, only a thin compound layer (Fe{sub 4}N, Fe{sub 3}N) was found, probably as a consequence of the rather slow nitrogen diffusion in the austenite matrix. For ASP 23 high speed steel, the different nitriding behaviour of the martensitic matrix causes the formation of a diffusion layer which results in an increase in hardness at the surface. On an analogous set of specimens the TiN deposition was started immediately after the plasma nitriding. To optimize this combined treatment, the influence ...

Energy Technology Data Exchange (ETDEWEB)

In 1996, the National Marine Fisheries Service and the University of Washington completed the fourth year of a multi-year study to estimate survival of juvenile salmonids (Oncorhynchus spp.) passing through dams and reservoirs on the Snake River. Actively migrating smolts were collected near the head of Lower Granite Reservoir and at Lower Granite Dam, tagged with passive integrated transponder (PIT) tags, and released to continue their downstream migration. Individual smolts were subsequently detected at PIT-tag detection facilities at Lower Granite, Little Goose, Lower Monumental, McNary, John Day and Bonneville Dams. Survival estimates were calculated using the Single-Release (SR) and Paired-Release (PR) Models. Timing of releases of tagged hatchery steelhead (O. mykiss) from the head of Lower Granite Reservoir and yearling chinook salmon (O. tshawytscha) from Lower Granite Dam in 1996 spanned the major portion of their juvenile ...

International Nuclear Information System (INIS)

Halide complexes of astatine cations At"+ and AtO"+ were prepared and their rate of migration was measured. The complexes are of the type AtX_2"- and AtOX_2"- (X = Cl"-, Br"-, I"-). The bromo complexes, AtBr_2"- and AtOBr_2"-, have a higher stability than the chloro complexes. The hydrolysis in weakly alkaline solution of AtX_2"- resulted At"-, and that of AtOX_2"- AtO_2"-. (author).

International Nuclear Information System (INIS)

Radionuclide techniques have commonly been used to assess ventriculovenous shunt function, cerebrospinal fluid dynamics, and for the diagnosis of cerebrospinal fluid leaks. All of these techniques were utilized in this unusual case of retrograde migration of a ventriculoatrial catheter into the neck, with cutaneous fistulization and CSF leak. (orig.).

International Nuclear Information System (INIS)

Nine-component vertical seismic profiling has been conducted at the UE-25 UZ No. 16 borehole at Yucca Mountain, Nevada, in support of investigation of the hydrologic significance of fault and fracture systems. A large data set from multi-component sources and receivers allows state-of-the-art advances in processing using polarization filtering and reverse time migration, for enhanced interpretation of geologic features.

Wastenet

... In spring, the marshes are filled with the atmospheric calls of lapwings and redshanks, all breeding on one of the UK's ...Butley river and Ore estuary, Boyton Marshes attracts breeding wading birds in spring and ducks, geese and swans in winter. It's also ... The moorland landscape looks especially colourful in late summer, while spring is the perfect time to come and see migrant birds like redstarts,...Valley This is a delightful oak woodland to walk through - especially in spring and early summer when lots of migrating birds come to breed ...

UK PubMed Central (United Kingdom)

Given the possibility of highly pathogenic H5N1 avian influenza arriving in North America and monitoring programs that have been established to detect and track it, we review intercontinental movements...Full Text Available

International Nuclear Information System (INIS)

Computed tomographic findings in developmental brain anomalies are more easily classified when the system used is based on embryogenesis related to morphology. Analysis of computed tomographic findings in a series of 154 patients with brain anomalies (Chiari malformation not included) revealed that specific examples of abnormalities occurring in major stages of brain development may be recognized by computed tomography. This paper deals with a group of patients with abnormalities that reflect a disturbance in neuronal migration. (orig.).

Energy Technology Data Exchange (ETDEWEB)

After a presentation of methods and tools for the basic and extensive characterization of polluted sites and the study of evolution and transfer of current organic pollutants in the ground, the example of the rehabilitation of an old Rhone-Poulenc site (at Chauny, France) polluted with metals and arsenic, is described: soil and aquifer diagnosis, risk analysis and determination of migration schemes

International Nuclear Information System (INIS)

Defects are produced in zinc by 6.1 MeV #alpha#-particle irradiation at 4.2 K and the subsequent recovery between 4.2 and 22 K. No evidence is found for free migration of an interstitial in the temperature range investigated. The recovery spectra reveal a series of substages which are ascribed to recombination of close Frenkel pairs. (author).

Energy Technology Data Exchange (ETDEWEB)

Two methods to cool muon beams deeply below the limit conventionally established for the ionization cooling are proposed. In Phase Ionization Cooling (PIC), the beam is focused at wedge absorber plates each half of particle oscillation period by imposing a weak parametric resonance along the beam path. The resonance growth of particle amplitude is surmounted by the ionization cooling. At optimum, such arrangement results in reduction of each of two transverse emittances by an order of value in addition to the preceding 6D ionization cooling. Next, resonance focusing and transverse cooling can be continued in the regime of a fast Reverse Emittance Exchange (REMEX). Here, the sign of the absorber wedge is opposite to PIC while the dispersion increased. REMEX to be accompanied by the bunch lengthening and acceleration in order to maintain the relative energy spread at an appropriate level. The limitations due to energy straggling in absorber will be evaluated, and possibilities of beam ...

Energy Technology Data Exchange (ETDEWEB)

Our inability to associate distant regulatory elements with the genes that they regulate has largely precluded their examination for sequence alterations contributing to human disease. One major obstacle is the large genomic space surrounding targeted genes in which such elements could potentially reside. In order to delineate gene regulatory boundaries we used whole-genome human-mouse-chicken (HMC) and human-mouse-frog (HMF) multiple alignments to compile conserved blocks of synteny (CBS), under the hypothesis that these blocks have been kept intact throughout evolution at least in part by the requirement of regulatory elements to stay linked to the genes that they regulate. A total of 2,116 and 1,942 CBS>200 kb were assembled for HMC and HMF respectively, encompassing 1.53 and 0.86 Gb of human sequence. To support the existence of complex long-range regulatory domains within these CBS we analyzed the prevalence and distribution of chromosomal aberrations ...

International Nuclear Information System (INIS)

We describe a panoramic stigmatic spectrograph comprising a grazing-incidence toroidal mirror and a large-aperture free-standing transmission diffraction grating (5000 lines mm-1 ). Two spectrograph versions were constructed, with grazing angles of 7.6 and 40 and the short-wavelength spectral limits near 4 and 1.5 nm. The spectrograph aberrations were studied by numerical ray tracing. The spectrograph was used to record line and quasi-continuous spectra (1.5 - 30 nm) of multiply charged ions in a plasma generated by the second-harmonic pulses of an yttrium aluminate laser (Q = 0.15 J, ? = 5 ns, ? = 0.54 ?m, repetition rate = 0.5 Hz). In combination with a laser-produced plasma radiation source, the arrangement was used to characterise soft x-ray optical components and to generate collimated beams of polarised radiation in the 14 - 20 nm range. (laser applications and other topics in quantum electronics)

British Library Electronic Table of Contents (United Kingdom)

Huntington?s disease (HD) is caused by an expansion of a polyglutamine repeat of more than 35?units in the huntingtin protein. The expanded repeat length is inversely correlated with the age at onset (AAO); however, additional genetic factors apart from the expanded CAG repeat length can modify the course and the AAO in HD. Aberrations in macroautophagy have been observed in Huntington, Alzheimer, Parkinson, motor neuron and prion diseases. Therefore, we hypothesized that polymorphisms in autophagy-related (Atg) genes might contribute to the variation in the AAO. We initially tested eight single nucleotide polymorphisms in five Atg genes (Atg3, Atg5, Atg7, Atg16L1 and Beclin-1) for their frequency of ?1%. Subsequently, we investigated the polymorphisms Atg7 V471A and Atg16L1 T281A for a di...

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to develop a foraging model that engenders large meals. Eight free-feeding baboons were first given periodic access to a chocolate sugar-coated candy (M & Ms?) and then a jelly sugar-coated candy (Skittles?). Baboons had access to food 24?h each day, but they had to complete a two-phase operant procedure in order to eat. Responding on one lever during a 30-min appetitive phase was required before animals could start a consumption phase, where responding on another lever led to food delivery, i.e., a meal. 3?days a week for 8 or 9?weeks baboons received candy during the first meal and then food pellets were available: a 2?month interval when only pellets were available separated periods of candy access. All baboons ate as much candy in the single candy meal as ...

Energy Technology Data Exchange (ETDEWEB)

To evaluate the efficacy of newly designed covered and non-covered coated colorectal stents for colonic decompression. Twenty-six patients, (15 palliative cases and 11 preoperative) underwent treatment for the relief of colorectal obstruction using metallic stents positioned under fluoroscopic guidance. In 24 of the 26, primary colorectal carcinoma was diagnosed, and in the remaining two, recurrent colorectal carcinoma. Twenty-one patients were randomly selected to receive either a type A or type B stent; for the remaining five, type C was used. Type A, an uncovered nitinol wire stent, was lightly coated to ensure structural integrity. Type B (flare type) and C (shoulder type) stents were polyurethane covered and their diameter was 24 and 26mm, respectively. The rates of technical success, clinical success, and complications were analyzed using the chi-square test, and to analyse the mean period of patency, the Kaplan-Meier method was used. Thirty of 31 attempted placements in 26 ...

British Library Electronic Table of Contents (United Kingdom)

Summary Background Pemphigus vulgaris and pemphigus foliaceus are rare, potentially life-threatening, autoimmune disorders characterized by antibodies to epidermal adhesion molecules. Clinical characteristics are painful chronic erosions of mucous membranes and of the skin. There are only few published studies on the impact of the disease on the health status (HS) of patients with these conditions. Objectives To assess the impact of disease on the HS of patients with pemphigus. Methods Fifty-eight patients enrolled at the Bullous Skin Diseases Unit of IDI-IRCCS in the period January-June 2006 were assessed for their HS using the Medical Outcomes Study 36-item short form health survey (SF-36) questionnaire and for anxiety and depression using the Institute for Personality and Ability Testin...

International Nuclear Information System (INIS)

Research highlights: ? Reports a high protection system for the alloy in corrosive environment. ? Describes an interfacial process with self-healing properties. ? Reports the influence of substrate pre-treatment in the coating performance. - Abstract: In this paper the interface of poly(vinylidene fluoride) coatings prepared by the dip coating method and HF-treated AZ31 magnesium alloy was evaluated. The best performance of this system in corrosion tests compared to ground, as-received and acetic acid cleaned substrates is related to an acid-base interaction at the interface and to interfacial reactions which resulted in a self-healing process. The protectiveness of the samples was investigated using impedance and immersion tests while the coating morphology and interface stability were investigated by scanning electron microscopy, X-ray photoelectron spectroscopy and adhesion tests.

British Library Electronic Table of Contents (United Kingdom)

Several compatibilising systems were added to high-density polyethylene (HDPE) and polyamide 6 (PA6) blends in the presence of an organically modified montmorillonite (OMM). All the blends were prepared by using a co-rotating twin-screw extruder and characterized by SEM, TEM and XRD analyses. In addition, the rheological behaviour and the mechanical properties - tensile and impact - were evaluated. The presence of OMM affects the dimensions of the polymeric phases in the blend but not their mutual adhesion, granted only by the compatibilisers. TEM, SEM and XRD analyses indicated that there is a strict correlation between the compatibilisation level and the final interlayer distance achieved by OMM. Even if some filled compatibilised blends showed a fairly good morphology - in terms of phas...

International Nuclear Information System (INIS)

When operating a nuclear power plant the necessity arise to eliminate various defects of building constructions, to seal joints and transitional elements. The authors present data concerning the production of a sealing composition made of epoxy resin and used for NPP premises of emergency location. Analytical relations are presented between the properties of the composition (adhesion strength, water absorption and others) and its structure. Physical, mechanical and thermal properties and structural peculiarities are determined in the process of interaction between the filling and binding agents. The composition sustains sealing properties under environmental conditions at he presence of an air - vapour mixture with 160 degrees C"o temperature and 0.3 MPa surplus pressure. (author).

British Library Electronic Table of Contents (United Kingdom)

Side-chain liquid crystalline ionomer (SLCI) containing sulfonic acid groups with a polymethylhydrosiloxane main-chain was used in the blends of polypropylene (PP) and polybutylene terephthalate (PBT) as a compatibilizer. The crystalline behavior, morphological, and mechanical properties of the blends were investigated in detail by differential scanning calorimetry (DSC), polarizing optical microscope (POM), Fourier transforms infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). Revealed by the shift of Tm in DSC thermogram and the shift of the absorbed peak in FTIR spectra, specific interaction led to stronger interfacial adhesion between these phases, which resulted in much finer dispersion of the minor PBT phase in PP matrix. The SLCI containing sulfonate acid groups ac...

Energy Technology Data Exchange (ETDEWEB)

The mechanical stability of diamond-like carbon (DLC) films coated on nitinol vascular stents was investigated under cyclic loading condition by employing a stent crimping system. DLC films were coated on the vascular stent of a three dimensional structure by using a hybrid ion beam system with rotating jig. The cracking or delamination of the DLC coating occurred dominantly near the hinge connecting the V-shaped segments of the stent where the maximum strain was induced by a cyclic loading of contraction and extension. However the failures were significantly suppressed as the amorphous Si (a-Si) buffer layer thickness increased. Interfacial adhesion strength was estimated from the spalled crack size in the DLC coating for various values of the a-Si buffer layer thickness.

British Library Electronic Table of Contents (United Kingdom)

In recent years, increased attention has been focused on the use of lasers in different fabrication steps of solar cells, in particular laser doping to form emitter and/or selective emitter. In this method the laser energy is used to melt silicon, allowing the diffusion of dopant atoms to occur in the liquid phase. The main advantage of this method is the localised nature of the laser beam, which melts and diffuses a limited area without heating the bulk, therefore reducing the possible degradation associated with high temperature processes. At the University of New South Wales a novel laser doping method was developed, which combines the formation of the selective emitter with a self-aligned metallisation pattern. Despite achieving high efficiencies, concerns arose regarding the adhesion ...

International Nuclear Information System (INIS)

Cell surface glycosaminoglycans play important roles in cell adhesion and viral entry. Laboratory strains of two alphaviruses, Sindbis and Semliki Forest virus, have been shown to utilize heparan sulfate as an attachment receptor, whereas Ross River virus (RRV) does not significantly interact with it. However, a single amino acid substitution at residue 218 in the RRV E2 glycoprotein adapts the virus to heparan sulfate binding and expands the host range of the virus into chicken embryo fibroblasts. Structures of the RRV mutant, E2 N218R, and its complex with heparin were determined through the use of electron cryo-microscopy and image reconstruction methods. Heparin was found to bind at the distal end of the RRV spikes, in a region of the E2 glycoprotein that has been previously implicated in cell-receptor recognition and antibody binding.

British Library Electronic Table of Contents (United Kingdom)

In many drug dispensing devices, such as syringes and inhalers, an elatomeric gasket is used to prevent the formulation from leaking from the chamber. During device actuation, the seal is subjected to friction, which in turn causes its deformation and can cause unintentional leakage, thus dose variability. Additionally, friction of seal is responsible for a host of potential problems such undue effort required for actuation and potential wear. The mechanism of friction generation in the seal conjunction is complex, arising from adhesion of rubber in contact with the moving interface, viscous action of a thin film of fluid and deformation of seal asperities. Therefore, the first step in understanding the conjunctional behaviour of rubber seals is a fundamental study of mechanisms of frictio...

British Library Electronic Table of Contents (United Kingdom)

Polyacrylonitrile (PAN)-based carbon fabric (CF) was modified with strong HNO3 oxidation and then introduced into polyimide (PI) composites. The friction and wear properties of the carbon fabric reinforced polyimide composites (CFRP), sliding against GCr15 stainless steel rings, were investigated on an M-2000 model ring-on-block test rig under dry sliding. Experimental results revealed that the carbon fiber surface treatment largely reduced the friction and wear of the CFRP. Compared with the untreated ones, the surface-modified CF can enhance the tribological properties of CFRP efficiently due to the improved adhesion between the CF and the PI matrix. Scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS) study of the carbon fiber surface showed that the fiber surfa...

British Library Electronic Table of Contents (United Kingdom)

The carbon fibers (CF) were pre-treated in two different ways: no pre-treatment, and activation in HNO3 plus application of toluene-2,4-diisocyanate (TDI). Carbon fibers have been introduced into polyurethane (PU) composite coatings. The tribological behaviors of the polyurethane composite coating filled with CF or TDI-modified CF (TDI-CF) were studied using a ring-on-block wear tester under dry sliding, and the worn surfaces of the filled PU coatings and transfer films formed on the surface of the counterpart ring sliding against the PU coating were investigated by SEM and optical microscope (OM), respectively. Owing to the effective improvement of the interfacial adhesion between the CF and polyurethane matrix, compared with the cases of untreated CF, the employment of low content TDI-CF...

British Library Electronic Table of Contents (United Kingdom)

Gastrointestinal patches represent a novel multiparticulate drug delivery system able to increase the intestinal absorption of drugs with poor bioavailability. The number of patches to administer is a critical issue since it is related to the surface and drug concentration at the absorption site. The objective of this article is to evaluate the effect of the number of administered patches on the final absorption of leuprolide, a peptide chosen as model drug, assuming complete adhesion of all the devices to the intestinal membrane. The same dose of leuprolide was encapsulated into 2, 4 and 6 patches; the resulting intestinal absorption profiles were measured with the Ussing chamber ex vivo experimental setup and compared between them. The results showed that varying the number of patches, t...

Energy Technology Data Exchange (ETDEWEB)

Several proposals have been made on the method of calculating generation of formaldehyde released from plywood. In calculating generation per hour of a volatile organic compound of adhesives or coatings using a chamber method, such models are frequently used that the generation is largest when the specimen is exposed in the chamber and that the generation attenuates with lapse of time. In the meantime, a number of studies for calculating formaldehyde generation from construction materials are often those determining a specific quantity of generation in a stationary state, while few studies are the observation of time series variation from immediately after the exposure into the chamber. Accordingly, the subject studies used lauan plywood as the samples and examined the method of calculating the change with lapse of time of the formaldehyde generation. (translated by NEDO)

Energy Technology Data Exchange (ETDEWEB)

Nuclear fuel cycle activities of the former Soviet Union (FSU) have resulted in massive contamination of the environment in western Siberia. We are developing three-dimensional numerical models of the hydrogeology and potential contaminant migration in the West Siberian Basin. Our long-term goal at Pacific Northwest Laboratory is to help determine future environmental and human impacts given the releases that have occurred to date and the current waste management practices. In FY 1993, our objectives were to (1) refine and implement the hydrogeologic conceptual models of the regional hydrogeology of western Siberia developed in FY 1992 and develop the detailed, spatially registered digital geologic and hydrologic databases to test them, (2) calibrate the computer implementation of the conceptual models developed in FY 1992, and (3) develop general geologic and hydrologic information and preliminary hydrogeologic conceptual models relevant to the more detailed ...

CERN Document Server

We present a new computation of the linear tidal interaction of a protoplanetary core with a thin gaseous disc in which it is fully embedded. For the first time a discussion of the orbital evolution of cores with eccentricity (e) significantly larger than the gas-disc scale height to radius ratio (H/r) is given. We find that the direction of orbital migration reverses for e>1.1H/r. This occurs as a result of the orbital crossing of resonances in the disc that do not overlap the orbit when the eccentricity is very small. Simple expressions giving approximate fits to the eccentricity damping rate and the orbital migration rate are presented. We go on to calculate the rate of increase of the mean eccentricity for a system of protoplanetary cores due to dynamical relaxation. By equating the eccentricity damping time-scale with the dynamical relaxation time-scale we deduce that an equilibrium between eccentricity damping and excitation through ...

Science.gov (United States)

The progress made during the first two years of a program to study the migration of grain boundaries in ceramic oxides is reported. The principal results of the program are concerned with the structure of grain boundaries in ..cap alpha..-Al/sub 2/O/sub 3/, although important new information has also been obtained on grain boundaries in spinels and both germanlum and silicon. Attention is focused on the basal twin boundary in ..cap alpha..-Al/sub 2/O/sub 3/ which had been identified as a model interface in early work. A series of new grain boundaries exemplified by the (11anti23) twin are also discussed briefly as is the rhombohedral twin interface. Earlier results on the first-order (..sigma..=3) twin in spinel have been extended with the development of models for the computer-simulation of high-resolution TEM images of these interfaces. A study of low-angle grain boundaries in spinel is giving new insight into the effect which the large size of the unit cell and ...

Energy Technology Data Exchange (ETDEWEB)

Recent organic geochemical studies differ radically in their interpretation of the origin of the Gulf coast oils. However all studies since (and including) Thompson, et al. 1989, emphasize the considerable geographic variation in genetic oil types and are in generalized agreement as to the genetic oil types present and their spatial and stratigraphic relationships. In particular it is accepted that the Gulf rim (both north and south) is encircled by a ring of Mesozoic carbonate-sourced oils and that there is also at least one major deep water trend of carbonate-sourced oils in the northern Gulf. It is also generally agreed that many of the Gulf rim oils are of Oxfordian-Kimmeridgian age, though some, like the Sunniland oils of Florida, are of lower Cretaceous origin. Major disagreement still occurs over the sources of the Louisiana offshore oils and onshore Wilcox reservoired oils. One {open_quotes}school of thought{close_quotes} assigns all these oils to Mesozoic sources. The other ...

Energy Technology Data Exchange (ETDEWEB)

Grout has been evaluated as a means of containing low-level radioactive waste for long-term disposal. Concerns about hydrogen and reactive gas generation in the Hanford Site grout disposal facility lead to the development of the G3 model, which has predicted buildup of radiolytically formed gases in the grout region and their migration to air-filled regions. The G3 model is a one-dimensional code that couples models of gas diffusion with two-phase gas and liquid flow. It was coupled to a compartment diffusion model and these models predicted the concentrations of hydrogen I nitrous oxide, and other gases in air-filled regions of the grout disposal facility. The results have served as the technical basis for safety studies. A unique finding of the G3 model was that a liquid return, or expulsion of unbound liquid from the grout region, could occur. This liquid return is driven by displacement caused by gas bubbles that form within the grout`s microstructure. Liquid ...

CERN Document Server

In culture migrating and interacting amoeboid cells can form nematic liquid crystal phases. A polar nematic liquid crystal is formed if the interaction has a polar symmetry. One type of white blood cells (granulocytes) form clusters where the cells are oriented towards the center. The core of such an orientational defect (disclination) is either a granulocyte forced to be in an isotropic state or another cell type like a monocyte. An apolar nematic liquid crystal is formed if the interaction has an apolar symmetry. Different cell types like human melanocytes (=pigment cells of the skin), human fibroblasts (=connective tissue cells), human osteoblasts (=bone cells), human adipocytes (= fat cells) etc., form an apolar nematic liquid crystal. The orientational elastic energy is derived and the orientational defects (disclination) of nematic liquid crystals are investigated. The existence of half-numbered disclinations show that the nematic phase has an apolar ...

International Nuclear Information System (INIS)

The mobility of oxidized astatine in solutions H(Na)ClO_4 (#mu#=0.4M)-1.10"-"4M K_2Cr_2O_7 has been measured at 25 degC in the interval 0.63<=pH<=1.68. Under these conditions astatine migrates to the cathode only. The speeds of the migration depends upon the concentration of hydrogen ions in solutions are: pH 1.68 Usub(c)=1.17.10"-"4 cm"2 V"-"1 s"-"1; pH 0.63 Usub(c)=2.67.10"-"4 cm"2 V"-"1 s"-"1. The effect agrees with the opinion that the singly charged cation of astatine formed in acidic solutions is a strong aquacomplex [(H_2O)sub(x)At]"+ (x=1-2) (protonated hypoastatic acid). Deprotonation constant of this cation is Ksub(dp)=0.032+-0.005. Specific properties of the astatine cation are given. They can be explained, probably, through the peculiarities of its structure. (author).

Science.gov (United States)

A mathematical model of 137Cs migration in forest ecosystem is presented, which describes the behaviour of this radionuclide in the forest litter-soil system, trees, understory and forest animals. The model's parameters for different types of forest ecosystems are estimated and model's adequacy is tested through the use of independent experimental data. The sensitivity of the model's output variables is analyzed to variations in the most significant parameters. The differences in the seasonal and mean annual dynamics of 137Cs concentration in muscles of roe deers and mooses are shown to be defined by specific features of the diets of these animals and variations in 137Cs content in the main diet components. PMID:11402557

Energy Technology Data Exchange (ETDEWEB)

This study was initiated to provide empirical data and analyses on the dam passage timing, travel rate, survival, and life history variation of fall Chinook salmon that are produced in the Clearwater River. The area of interest for this study focuses on the lower four miles of the Clearwater River and its confluence with the Snake River because this is an area where many fish delay their seaward migration. The goal of the project is to increase our understanding of the environmental and biological factors that affect juvenile life history of fall Chinook salmon in the Clearwater River. The following summaries are provided for each of the individual chapters in this report.

Energy Technology Data Exchange (ETDEWEB)

Transient, greatly enhanced diffusion has been observed on annealing solid-phase-epitaxial (SPE) grown Si-Sb alloys. This is shown to be due to a high concentration of interstitials being trapped during SPE regrowth. The migration enthalpy, for diffusion of Sb by an interstitialcy mechanism was measured as 1.8 +/- 0.2 eV. The interstitials eventually condensed into loops, marking the end of the transient. In a SPE grown Si-Bi alloy a similar transient enhanced diffusion was observed, with an activation energy of 2.0 +/- 0.2 eV, but no loops formed. 8 figures, 7 references.

Energy Technology Data Exchange (ETDEWEB)

This invention refers to the organic geochemistry and can be used in prospecting for oil and gas. The method includes taking samples of rocks, extracting from them the chloroform bitumoid and its thermal processing. In order to improve the accuracy, the equal quantities of bitumoid taken are exposed to gradual thermal treatment to temperatures exceeding the thresholds of thermal stability of sulfur-containing compounds, in each temperature interval, the content of hydrogen sulfide released in this case is revealed, and by its drastic increase at temperatures corresponding to the temperatures of the productive part of the section, a conclusion is drawn about the epigenetic nature of the bitumoid. The method makes it possible to improve the resolution of the bituminological prospecting for oil and gas.

British Library Electronic Table of Contents (United Kingdom)

Epitaxial thin films of nanotwinned face-centered cubic metals such as Cu possess an unprecedented combination of high hardness and high electrical conductivity due to the unique structure of nanometer-spaced coherent twin boundaries. Recent studies of in-situ nanoindentation in a transmission electron microscope have provided new insights on the deformation behavior of nanotwins that are reviewed here. In particular, two unit processes are highlighted: first, stress-induced migration of ?3 {112} incoherent twin boundary that leads to de-twinning of nanotwins; second, twinning dislocation can be multiplied at ?3 {111} coherent twin boundary.

International Nuclear Information System (INIS)

We have investigated the formation and coarsening of Ga droplets on focused-ion-beam (FIB) irradiated GaAs surfaces. To separately examine formation and coarsening, Ga droplets were fabricated by Ga"+ FIB irradiation of GaAs substrates with and without pre-patterned holes. We determined the droplet growth rate and size distribution as a function of FIB energy following irradiation. The data suggest a droplet formation mechanism that involves Ga precipitation from a Ga-rich layer, followed by droplet coarsening via a combination of diffusion and Ostwald ripening or coalescence via droplet migration (dynamic coalescence).

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In the presented case study CRS processing was able to improve the overall data quality of the processed lines in terms of signal-to-noise ratio and imaging. The complex geology is causing serious problems in conventional NMO/DMO processing that were solved by CRS processing. Even a depth processing with velocities calculated from CRS attributes gives good results similar to those from PreSDM in terms of the velocity field. Data quality of poststack depth migrated CRS stacks is even better than the image from PreSDM. (orig.)

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The passive continental margin in the northern South China Sea is a weakly active area. It has been found to be favorable for large gas field development and also to be profitable for gas hydrate. The active faults, diapir structure, slump deposits, faults break of slopes, gas chimneys and sandstone of submarine fan, control the concentration of gas hydrate. Gas chimneys are widely distributed in the northern South China Sea. They supply the pathway for migration of deeper gas to gas hydrate stability zones especially in the basin of tectonic inactive zone. This paper discussed the geological structures of gas hydrate occurrence in gas fields and presented a detailed analysis of gas chimneys within the northern slope of the South China Sea. The paper described the geological setting of the Qiongdongnan Basin and provided information on the data description and processing. Two multichannel seismic (MCS) reflection profiles were used for the study. In order to ...

International Nuclear Information System (INIS)

This paper reports about in-situ corrosion studies on selected materials for long-term resistant high-level waste (HLW) packagings acting as a barrier in a rock salt repository. The materials (Ti 99.8-Pd, Hastelloy C4 and five iron-base materials) were investigated in heated boreholes in the Asse salt mine under simulated HLW disposal conditions prevailing in normal operation of repository and in certain accident scenarios. The experiments under normal operating conditions were performed at temperatures of 120 deg. C to 210 deg. C (vertical temperature profile in the boreholes) without and with gamma irradiation (3#centre dot#10"2 Gy/h, Co-60 source) within the framework of the German/US Brine Migration Test. In these experiments only small amounts of migrated brine inclusions (NaCl-rich) from the rock salt were present as corrosion medium. In the experiments carried out under simulated accident conditions with intrusion of larger amounts of ...

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A general space- and energy-dependent formalism is developed in order to analyze zero-power neutron noise experiments in fast reactor systems. A generalized dispersion equation is combined with theoretical expressions for the experimentally measured power spectral density and variance-to-mean ratio which makes it possible to express these quantities in terms of a double moment of the Laplace and Fourier transformed Green's function of a slowing-down operator rather than those of the full Boltzmann operator. Several spatial approximations are analyzed in the context of the general formalism. In each case, the power spectral density and variance-to-mean ratio are written in terms of an appropriate fast reactor dispersion law for the medium which can be calculated from the solution to a simple slowing-down equation. The resultant expression for the power spectral density are analyzed for various combinations of neutron migration descriptions, slowing-down ...

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The author presents and analyzes three approaches to calculating explicit two-dimensional (2D) depth-extrapolation filters for all propagation modes (P, SV, and SH) in transversely isotropic media with vertical and tilted axis of symmetry. These extrapolation filters are used to do 2D poststack depth migration, and also, just as for isotropic media, these 2D filters are used in the McClellan transformation to do poststack 3D depth migration. Furthermore, the same explicit filters can also be used to do depth-extrapolation of prestack data. The explicit filters are derived by generalizations of three different approaches: the modified Taylor series, least-squares, and minimax methods initially developed for isotropic media. The examples here show that the least-squares and minimax methods produce filters with accurate extrapolation (measured in the ability to position steep reflectors) for a wider range of propagation angles than that obtained ...

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The results of the 2006 investigation of contaminant sources at Navarre, Kansas, clearly demonstrate the following: {sm_bullet} Sources of carbon tetrachloride contamination were found on the Navarre Co-op property. These sources are the locations of the highest concentrations of carbon tetrachloride found in soil and groundwater at Navarre. The ongoing groundwater contamination at Navarre originates from these sources. {sm_bullet} The sources on the Co-op property are in locations where the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) never conducted grain storage operations. {sm_bullet} No definitive sources of carbon tetrachloride were identified on the portion of the current Co-op property formerly used by the CCC/USDA. {sm_bullet} The source areas on the Co-op property are consistent with the locations of the most intense Co-op operations, both historically and at present. The Co-op historically stored carbon tetrachloride for retail sale and used ...

Science.gov (United States)

Objective: To determine whether asymptomatic bacterial vaginosis (BV) is associated with upper genital tract inflammation or bacterial colonization.Methods: Fifty nonpregnant women with intact uteri who planned to undergo gynecologic surgery and had no recent symptoms of vaginal infection were enrolled. We obtained a vaginal swab for Gram stain, endocervical swab for chlamydia and gonorrhea DNA probe testing, and Pipelle endometrial biopsy for aerobic and anaerobic cultures and histology. We correlated surgical findings and histology of available surgical specimens with the microbiologic results. The diagnosis of BV was made according to Speigel's criteria. Bacteria isolated from the uterus were classified as high virulence versus low virulence. Contingency tables were analyzed using the chi-square or Fisher Exact tests.Results: Twenty-one of 50 patients had BV on Gram stain, 3 had intermediate BV, and 3 had unreadable slides. Eleven patients had histologic endometritis, including 7 of ...

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Influenza virus infection during pregnancy has been implicated as one of cause of premature delivery, abortion and stillbirth. We have reported that cultured human fetal membrane chorion cells undergoing apoptosis by influenza virus infection secrete unidentified heat-stable monocyte differentiation-inducing (MDI) factors. In this study, cellular, biological and immunochemical characteristics of MDI factors were investigated using human monocytic leukemia THP-1 cells by nitroblue tetrazolium reduction and cell adhesion assays. The treatment of THP-1 cells with culture supernatants from the influenza virus-infected chorion cells induced the nitroblue tetrazolium reduction ability, which was inhibited by the addition of superoxide dismutase and diphenyleneiodonium chloride, an inhibitor for reduced nicotinamide adenine dinucleotide phosphate oxidase. The phenomenon was also observed in human peripheral blood monocytes and histiocytic leukemia U937 cells, but not in ...

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Natural bone consists of hard nanostructured hydroxyapatite (HA) in a nanostructured protein-based soft hydrogel template (ie, mostly collagen). For this reason, nanostructured HA has been an intriguing coating material on traditionally used titanium for improving orthopedic applications. In addition, helical rosette nanotubes (HRNs), newly developed materials which form through the self-assembly process of DNA base pair building blocks in body solutions, are soft nanotubes with a helical architecture that mimics natural collagen. Thus, the objective of this in vitro study was for the first time to combine the promising attributes of HRNs and nanocrystalline HA on titanium and assess osteoblast (bone-forming cell) functions. Different sizes of nanocrystalline HA were synthesized in this study through a wet chemical precipitation process following either hydrothermal treatment or sintering. Transmission electron microscopy images showed that HRNs aligned with nanocrystalline HA, which ...

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Ramsar, a city in the northern Iran, has the highest level of natural background radiation in the world. It has been clearly shown that low doses of ionising radiation can induce resistance to subsequent higher exposures. This phenomenon is termed radioadaptive response. We have compared induction of cytogenetic radioadaptive response by High Natural Background Radiation (HNBR) in Ramsar and X-ray occupational exposure as conditioning doses in human peripheral blood lymphocytes. 30 healthy control individuals, living in Ramsar but in normal background radiation areas, 15 healthy individuals from Talesh Mahalleh, a region with extraordinary high level of background radiation, and 7 X-ray radiographers working in Ramsar hospital located in normal natural background ionising radiation area were evaluated. Peripheral blood samples were prepared and exposed to challenge dose of 0 and 2 Gy. Lymphocytes were scored using analysis of metaphase, for the presence of chromosomal ...

International Nuclear Information System (INIS)

The development of leukemia and thyroid cancer is characterized by activation of the abl oncogene and ret oncogene, respectively. In order to clarify the relationship between these gene aberrations and radiation, the pro-myelogenous leukemia-derived cell line HL60 and the thyroid cancer-derived cell line 8505C, were irradiated in vitro with 100Gy of X-rays. RNA was then extracted from 10"8 cells of the respective cell lines and examined by the reverse transcription PCR method for rearrangements of abl and ret genes. Five kinds of positive bands were observed in the HL-60 cells irradiated with 100Gy of X-ray. Similarly, six positive bands were also observed in the 8505C cells irradiated with 100Gy. In vitro X-irradiation activation of oncogenes found in radiation induced cancers imply that gene rearrangement by X-rays is involved in the development of malignant tumors. Furthermore, in an experiment to detect radiation effects in A-bomb survivors, RNA was extracted ...

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A crucial step in human breast cancer progression is the acquisition of invasiveness. There is a distinct lack of human cell culture models to study the transition from pre-invasive to invasive phenotype as it may occur 'spontaneously' in vivo. To delineate molecular alterations important for this transition, we isolated human breast epithelial cell lines that showed partial loss of tissue polarity in three-dimensional reconstituted-basement membrane cultures. These cells remained non-invasive; however, unlike their non-malignant counterparts, they exhibited a high propensity to acquire invasiveness through basement membrane in culture. The genomic aberrations and gene expression profiles of the cells in this model showed a high degree of similarity to primary breast tumor profiles. The xenograft tumors formed by the cell lines in three different microenvironments in nude mice displayed metaplastic phenotypes, including squamous and basal ...

International Nuclear Information System (INIS)

Spent nuclear wastes are inevitable issues to use nuclear power as a sustainable energy. Therefore, every country has their fuel cycles which are best for their environmental and/or political circumstances for the use of nuclear energy. These days agreements are made that spent nuclear fuels should be recycled to minimize waste volume and its toxicity all around the world. Republic of Korea also has a plan to recycle the spent nuclear fuels by using Gen-IV concept burner reactors and pyro-process plants. Not many options of national nuclear strategies are exist because Korea has too many people for its limited land space. KAERI already has been proposing a national fuel cycle concept called 'KIEP-21' that encompasses all the requirements of the advanced nuclear fuel cycle such as reduction of volume, toxicity, HLW heat load and so on. Authors suggest non-national fuel cycle concept called 'PyroGreen' for the sustainable nuclear energy system. PyroGreen is also comprised of ...

British Library Electronic Table of Contents (United Kingdom)

The X-ray storage phosphor CsBr:Eu2+ in form of needle image plates is believed to be a promising alternative to the granular BaFBr:Eu2+ with regard to PSL yield and spatial resolution. Unfortunately, CsBr:Eu2+ exhibits poor radiation hardness, which is caused by a migration of europium ions initiated by naturally existing defect centers like (Eu2+-VCs)-centers and X-ray generated MEu-centers. It will be shown that the formation of (Eu2+-O2?)-dipoles at the expense of (Eu2+-VCs)-dipoles, incorporated by thermal annealing in O2-containing and humid atmosphere, does not improve the radiation stability. There is, however, a strong improvement in the radiation hardness by codoping of CsBr:Eu2+ with lithium ions, which is accompanied by a complete suppression of the previously observed MEu-cent...

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The nickel-rich superalloys Alloy 600 and Alloy 800 have been corroded in mildly alkaline deuterated aqueous conditions typical of secondary coolant circuits in a nuclear power station. The oxide films and substrates of these alloys have been analysed by imaging SIMS depth profiling, which makes it possible to describe elemental distribution in all three dimensions. The measurement of the distribution of the secondary ions NiO[sup -], FeO[sup -] and CrO[sup -] appears useful for detailing the behaviour of nickel, iron and chromium within oxidized phases. The measurement of D[sup -] distribution outlines the extent of oxide hydration. For Alloy 800, evidence of sodium migration into the grain boundaries of the alloy substrate is found. For Alloy 600, no grain boundary sodium ingress can be identified under comparable corrosion conditions. (author).

International Nuclear Information System (INIS)

After the publication of the 2nd progress report of geological disposal of TRU waste in Japan, policy and general scheme of future study for the waste disposal in Japan was published by ANRE and JAEA. This annual report summarized aim and progress of individual problem, which was assigned into JAEA in the published policy and general scheme. The problems are as follows; characteristics of TRU waste and its geologic disposal, treatment and waste production, quality control and inspection methodology for waste, mechanical analysis of near-field, data acquisition and preparation on radionuclides migration, cementitious material transition, bentonite and rock alteration in alkaline solution, nitrate effect, performance assessment of the disposal system and decomposition of nitrate as an alternative technology. (author)

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Abstract Introduction. Spinal cord stimulation (SCS) is an effective procedure for the treatment of neuropathic extremity pain, with success rates approaching 70%. However, mechanical failures, including breakage and migration, can significantly limit the long-term effectiveness of SCS. A systematic analysis of surgical techniques was undertaken by a consensus group, coupled with extensive in vivo and in vitro biomechanical testing of system components. Methods. A computer model based on morphometric data was used to predict movement in a standard SCS system between an anchored lead and pulse generator placed in various locations. These displacements were then used to determine a realistic range of forces exerted on components of the SCS system. Laboratory fixtures were constructed to subj...

Science.gov (United States)

A methodology and hypothetical case study are presented for incorporation of uncertainty and variability into calculations of human health risk appropriate for regional, or basin-scale, groundwater management problems. Uncertainty in well water concentration is introduced through complex contaminant migration patterns in the subsurface. Variability is considered in parameters related to individual behavior patterns and biological effects and to groundwater extraction and distribution networks. A joint uncertainty and variability (JUV) analysis is used to generate a two-dimensional distribution or risk surface that spans both transport uncertainty as well as individual variability. Cuts in this distributional surface (fractiles of variability and percentiles of uncertainty) are presented and discussed. Comparisons with alternative approaches based upon deterministic transport models are also made. In addition, important distinctions are made between the case where ...

British Library Electronic Table of Contents (United Kingdom)

This study provides a comprehensive description of the main morphological and histological events that take place during larval and post-larval development of Senegal sole Solea senegalensis in order to establish a reference for its normal developmental organogenesis. Five stages have been described. Before gill development at the onset of metamorphosis (eye migration process, stage 4c), the skin was the main site of gas and ion exchange, whereas during stages 3 and 4, the skin begins differentiating into the definitive juvenile structure. The timing of development of the endocrine system depends on each organ, the endocrine pancreas and thyroid gland being the first to differentiate (stages 2 and 3, respectively), followed by the interrenal tissue and stannius corpuscles that develop at m...

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The Mississippi Office of Geology has conducted field trials using the surface exploration techniques of geomicrobial, radiometrics, and free soil gas. The objective of these trials is to determine if Mississippi oil and gas fields have surface hydrocarbon expression resulting from vertical microseepage migration. Six fields have been surveyed ranging in depth from 3,330 ft to 18,500 ft. The fields differ in trapping styles and hydrocarbon type. The results so far indicate that these fields do have a surface expression and that geomicrobial analysis as well as radiometrics and free soil gas can detect hydrocarbon microseepage from pressurized reservoirs. All three exploration techniques located the reservoirs independent of depth, hydrocarbon type, or trapping style.