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A-3 Test Stand construction update
The concrete foundation placed Dec. 18 (foreground) for Stennis Space Center's future A-3 Test Stand has almost completely cured by early January, according to Bo Clarke, NASA's contracting officer ...
Water tank installed at A-3 Test Stand
A water tank is lifted into place at the A-3 Test Stand being built at NASA's John C. Stennis Space Center. Fourteen water, liquid oxygen (LOX) and isopropyl alcohol (IPA) tanks are being installed to ...
Water tank installed at A-3 Test Stand
A water tank is lifted into place at the A-3 Test Stand being built at NASA's John C. Stennis Space Center. Fourteen water, liquid oxygen (LOX) and isopropyl alcohol (IPA) tanks are being installed to ...
Liquid oxygen tank installed at A-3 Test Stand
A liquid oxygen (LOX) tank is lifted into place at the A-3 Test Stand being built at NASA's John C. Stennis Space Center. Fourteen LOX, isopropyl alcohol (IPA) and water tanks are being installed to ...
Liquid oxygen tank installed at A-3 Test Stand
A liquid oxygen (LOX) tank is lifted into place at the A-3 Test Stand being built at NASA's John C. Stennis Space Center. Fourteen LOX, isopropyl alcohol (IPA) and water tanks are being installed to ...
Isopropyl alcohol tank installed at A-3 Test Stand
An isopropyl alcohol (IPA) tank is lifted into place at the A-3 Test Stand being built at NASA's John C. Stennis Space Center. Fourteen IPA, water and liquid oxygen (LOX) tanks are being installed to ...
Isopropyl alcohol tank installed at A-3 Test Stand
An isopropyl alcohol (IPA) tank is lifted into place at the A-3 Test Stand being built at NASA's John C. Stennis Space Center. Fourteen IPA, water and liquid oxygen (LOX) tanks are being installed to ...
Engineers conduct key water test for A-3 stand
Water cascades from the A-2 Test Stand at Stennis Space Center as engineers challenge the limits of the high-pressure water system as part of the preparation process for the A-3 Test Stand ...
Water storage vessels for the A-3 Test Stand are delivered to Stennis on Aug. 12.
Water storage vessels for the A-3 Test Stand are delivered to Stennis on Aug. 12.
Last scheduled SSME removed after firing
Space shuttle main engine No. 0525 is lifted from the A-2 Test Stand at Stennis Space Center against the backdrop of the new A-3 Test Stand under construction, offering a glimpse of the ...
Planning for Plume Diagnostics for Ground Testing of J-2X Engines at the SSC
... ground-breaking ceremony for the new A-3 rocket engine test stand took place at SSC on August 23, 2007. A-3 is the first large - scale test stand to ...
Construction of the A-3 Test Stand approaches another milestone with delivery and installation of water, isopropyl alcohol (IPA) and liquid oxygen (LOX) tanks. The three LOX tanks shown on the left and ...
Keesler Air Force Base team tours Stennis
... toured several areas, including the A-3 Test Stand construction site and the Pratt & Whitney Rocketdyne engine assembly facility. Management team members visiting Stennis ...
Mississippi lieutenant governor visits Stennis
Stennis Space Center Director Gene Goldman (left) stands with Mississippi Lt. Gov. Phil Bryant at the A-3 Test Stand construction site during an Oct. 1 visit by the state official. During his ...
The Ares Launch Vehicles: Critical for America's Continued Leadership in Space
... scenes: from the construction of the A-3 test stand, construction of portions of the vehicles, through various tests of the components of the Ares Launch Vehicles, ...
Engine Gimbal Requirements for Ground Testing of J-2X
... at test stands A-1, A-2, and A-3 at Stennis Space Center(SSC) in Bay St. Louis, Mississippi. Gimbal requirements and stage interface conditions were investigated by applying a ...
http://hdl.handle.net/1959.14/74881
"Us and them" or "United we stand, divided we fall"?: the singular versus the universal in the history of language -- 2. Globalisation and its impact on attitudes to language in international business -- 3. Sex, lies and stereotypes: putting cultural tips for doing business in France to the test -- 4. Foreign language use in business: surveying the surveys -- 5. Survey methodology: if at first you do not succeed... think of Descartes and turn to PR -- 6. When a picture is not necessarily worth a thousand words: behaviour and attitudes of New Zealand companies in the French market -- 7. Views from the "other" side: French reactions to the linguistic and cultural efforts of their New Zealand partners in the French market -- Conclusion. Publisher: Saarbrücken : VDM Verlag Dr. Müller Contributor: Macquarie University. Dept. of European Languages Other identifier: ISBN:9783639102697; mq-rm-2007010275 Language: eng
http://espace.library.uq.edu.au/view/UQ:76035
The aim of this study was to examine the reliability and validity of field tests for assessing physical function in mid-aged and young-old people (55-70 y). Tests were selected that required minimal space and equipment and could be implemented in multiple field settings such as a general practitioner's office. Nineteen participants completed 2 field and I laboratory testing sessions. Intra-class correlations showed good reliability for the tests of upper body strength (lift and reach, R=.66), lower body strength (sit to stand, R=.80) and functional capacity (Canadian Step Test, R=.92), but not for leg power (single timed chair rise, R=.28). There was also good reliability for the balance test during 3 stances: parallel (94.7% agreement), semi-tandem (73.7%), and tandem (52.6%). Comparison of field test results with objective laboratory measures found good validity for the sit to stand (cf 1RM leg press, Pearson r=.68, p .05), balance (r=-.13, -.18, .23) and rate of force development tests (r=-.28). It was concluded that the lower body strength and cardiovascular function tests were appropriate for use in field settings with mid-aged and young-old adults. Publisher: Sports Medicine Australia Relation: isMemberOf School of Human Movement Studies Publications; isMemberOf Excellence in Research Australia (ERA) - Collection
http://espace.library.uq.edu.au/view/UQ:13062
The aim of this study was to examine the reliability and validity of field tests for assessing physical function in mid-aged and young-old people (55–70 y). Tests were selected that required minimal space and equipment and could be implemented in multiple field settings such as a general practitioner's office. Nineteen participants completed 2 field and 1 laboratory testing sessions. Intra-class correlations showed good reliability for the tests of upper body strength (lift and reach, R= .66), lower body strength (sit to stand, R= .80) and functional capacity (Canadian Step Test, R= .92), but not for leg power (single timed chair rise, R= .28). There was also good reliability for the balance test during 3 stances: parallel (94.7% agreement), semi-tandem (73.7%), and tandem (52.6%). Comparison of field test results with objective laboratory measures found good validity for the sit to stand (cf 1RM leg press, Pearson r= .68, p .05), balance (r= −.13, −.18, .23) and rate of force development tests (r= −.28). It was concluded that the lower body strength and cardiovascular function tests were appropriate for use in field settings with mid-aged and young-old adults. Relation: isMemberOf School of Human Movement Studies Publications; isMemberOf Excellence in Research Australia (ERA) - Collection Coverage: 2005-03-01 00:00:00
http://espace.library.uq.edu.au/view/UQ:123267
Study Design. An in vitro study was conducted to determine the biomechanical properties of a new simple, percutaneous, posterior fixation technique for the lumbar spine involving a new implant, the so-called Lumbar Facet Interference Screw. Objectives. The purpose of this study was to compare the biomechanical properties of this new fixation device with translaminar and pedicle screw fixation. Summary of Background Data. Several techniques were described to perform a minimal invasive posterior stabilization of the lumbar spine after an anterior lumbar interbody fusion procedure. Yet, due to the high complexity of these minimally invasive surgical procedures, currently, hardly any of these percutaneous posterior fixation techniques is carried out routinely. Methods. Ten human lumbar spines were tested in flexion, extension, axial rotation, and lateral bending using a nonconstrained testing method. First, all motion segments were evaluated intact (group 1). After complete discectomy of L4-L5, the following stabilization techniques were tested sequentially (n=10/group): group 2: "stand-alone" cage; group 3: cage plus translaminar screws; group 4: cage plus Lumbar Facet Interference Screw; and group 5: cage plus pedicle screws. Stiffness, ranges of motion, and neutral and elastic zones were determined. Results. In comparison to the intact motion segment, the "stand-alone" cage showed a significantly higher (P<0.05) range of motion, neutral zone, and elastic zone and a significantly lower (P<0.05) stiffness in extension and rotation. Generally, all fixation techniques using cages plus posterior stabilization decreased range of motion, neutral zone, and elastic zone and increased stiffness in comparison to the "stand-alone" cage group. There was no significant difference between the cage plus interference screw and the cage plus translaminar screw group in all test modes. In comparison to the 2 facet joint stabilization techniques, pedicle screw stabilization decreased (P<0.01) range of motion, neutral zone, and elastic zone and increased (P<0.01) stiffness significantly in flexion and rotation. Conclusions. Results of this study indicate that the new Lumbar Facet Interference Screw fixation yields initial biomechanical stability similar to translaminar screw fixation, yet inferior biomechanical stability compared to pedicle screw fixation. Although these results are encouraging, additional biomechanical studies including cyclic loading tests have to evaluate the mid- and long-term stabilization capacity of this new minimally invasive fixation technique before human application. Relation: isMemberOf School of Veterinary Science Publications; isMemberOf Excellence in Research Australia (ERA) - Collection Coverage: 2005-01-15T00:00:00Z
http://espace.library.uq.edu.au/view/UQ:120873
Reduced gravity experimentation is important to many research groups working in various fields investigating both fundamental and applied aspects of diverse physical phenomena. Very few terrestrial or extra-terrestrial experimental facilities are currently available that allow researchers access to reduced gravity environments. The Queensland University of Technology’s has recently (2006) decommissioned a 1.9 second drop tower adapted for operation within an unused lift well of a building and has fabricated a purpose built, stand alone 2.0 second drop tower specifically to accommodate reduced gravity experimentation. The specifications and operational procedures of this new research facility are presented. Information concerning current and future areas of research is also presented and discussed. These research areas include: 1) cellular biology, 2) fluid dynamics and multiphase flow, 3) nanomaterial production including silica sol-gels and carbon nanotubes, and 4) heterogeneous combustion with a focus on bulk metallic materials burning in oxygen enriched atmospheres performed in collaboration with NASA and industry partners. Opportunities will also be discussed regarding both collaborative research and the provision of reduced gravity test services. Contributor: Peter Jacobs; Tim McIntyre; Matthew Cleary; David Buttsworth; David Mee; Rose Clements; Richard Morgan; Charles Lemckert Coverage: 2007-01-01T00:00:00Z
http://epublications.bond.edu.au/blr/vol7/iss2/4
[extract] The judgments have largely reinstated the views underlying the three traditional British cases in this area, namely, Brown v British Abrasive Wheel Co, Dafen Tinplate Co v Llanelly Steel Co and Sidebottom v Kershaw, Leese & Co. These cases stand for the principle that it is not permissible, in the absence of a specific statutory power, for the majority to alter the articles so that it can, simply for its own benefit, eliminate the minority.This short article examines the legal and intellectual bases for the judgments and concludes there is both a proper purpose test and a concept of fairness which are being appealed to by the High Court. A number of issues are referred to briefly, including the High Court's treatment of views on shares as an item of property, their view on section 180(3) of the Corporations Law and some possible implications for the future. Publisher: ePublications@bond Format: application/pdf Source: Bond Law Review
http://eprints.utas.edu.au/8977/
The natural age structure of wet eucalypt forest has important implications for biodiversity conservation and the mode of wood production. Southern Tasmanian wet eucalypt forests were sampled to describe age class variation and to test the following hypotheses that relate to it: (1) Eucalyptus regnans stands are more likely to be single-cohort than Eucalyptus obliqua and mixed stands; (2) old-growth trees are associated with multi-cohort wet eucalypt forests; (3) the E. regnans stands are more multi-cohort than Victorian E. regnans stands. Data from 762 stands, all with either E. obliqua or E. regnans were analysed to determine how stand characteristics related to forest type and to the presence of old-growth trees. Over half the stands studied were multi-cohort. Stands with E. regnans had a lesser tendency towards multi-cohortness than stands lacking this species, although most old-growth stands, including those dominated by E. regnans, were multi-cohort. In contrast, most regrowth stands of all species combinations were single-cohort. The proportions of E. regnans stands that were multi-cohort were similar to some estimates from the same type of forest in Victoria. Modifications of forestry regimes in wet eucalypt forests could help to maintain the existence of these biodiverse multi-cohort forests in the landscape. Relation: Turner, PAM and Balmer, J and Kirkpatrick, JB Stand-replacing wildfires? The incidence of multi-cohort and single-cohort Eucalyptus regnans and E. obliqua forests in southern Tasmania. Forest Ecology and Management, 258 (4). pp. 366-375. ISSN 0378-1127 Format: application/pdf
http://eprints.qut.edu.au/28573/
Introduction and Aims: Remote delivery of interventions is needed to address large numbers of people with alcohol use disorders who are spread over large areas. Previous correspondence trials typically examined its effects as stand-alone treatment. This study aimed to test whether adding postal treatment to general practitioner (GP) support would lower alcohol use more than GP intervention alone. Design and Methods: A single-blind, randomised controlled trial with a crossover design was conducted over 12 months on 204 people with alcohol use disorders. Participants in an immediate correspondence condition received treatment over the first 3 months; those receiving delayed treatment received it in months 3–6. Results: Few participants were referred from GPs, and little intervention was offered by them. At 3 months, 78% of participants remained in the study. Those in immediate treatment showed greater reductions in alcohol per week, drinking days, anxiety, depression and distress than those in the delayed condition. However, post-treatment and follow-up outcomes still showed elevated alcohol use, depression, anxiety and distress. Greater baseline anxiety predicted better alcohol outcomes, although more mental distress at baseline predicted dropout. Discussion and Conclusions: The study gave consistent results with those from previous research on correspondence treatments, and showed that high levels of participant engagement over 3 months can be obtained. Substantial reductions in alcohol use are seen, with indications that they are well maintained. However, many participants continue to show high-risk alcohol use and psychological distress. Publisher: Australasian Professional Society on Alcohol and other Drugs Relation: DOI:10.1111/j.1465-3362.2008.00011.x; Kavanagh, David and Connolly, Jennifer M. (2009) Mailed treatment to augment primary care for alcohol disorders : a randomised controlled trial. Drug and Alcohol Review, 28(1). pp. 73-80. Format: application/pdf Rights: Copyright 2009 Australasian Professional Society on Alcohol and other Drugs
http://eprints.qut.edu.au/14492/
Reduced gravity experimentation is important to many research groups working in various fields investigating both fundamental and applied aspects of diverse physical phenomena. Very few terrestrial or extra-terrestrial experimental facilities are currently available that allow researchers access to reduced gravity environments. The Queensland University of Technology’s has recently (2006) decommissioned a 1.9 second drop tower adapted for operation within an unused lift well of a building and has fabricated a purpose built, stand alone 2.0 second drop tower specifically to accommodate reduced gravity experimentation. The specifications and operational procedures of this new research facility are presented. Information concerning current and future areas of research is also presented and discussed. These research areas include: 1) cellular biology, 2) fluid dynamics and multiphase flow, 3) nanomaterial production including silica sol-gels and carbon nanotubes, and 4) heterogeneous combustion with a focus on bulk metallic materials burning in oxygen enriched atmospheres performed in collaboration with NASA and industry partners. Opportunities will also be discussed regarding both collaborative research and the provision of reduced gravity test services. Publisher: School of Engineering, The University of Queensland Relation: Steinberg, Ted (2007) Reduced Gravity Testing and Research Capabilities at Queensland University of Technology's New 2.0 Second Drop Tower. In: 16th Australasian Fluid Mechanics Conference (AFMC), 3-7 December, 2007, Gold Coast, Queensland. Format: application/pdf Rights: Copyright 2007 Ted Steinberg
http://eprints.jcu.edu.au/5900/1/5900_Likoswe_%26_Lawn_2008.pdf
The response to terminal water deficit stress of three grain legumes, soybean, cowpea and pigeonpea, was evaluated in plants grown in large tubes, in competition with either the same species or one of the other two species. The aim was to explore how species differences in drought response affected water use, growth and survival of plants in pure stand and in competition. Two plants, comprising the test species and its competitor, were grown in each tube. Water was withheld 26 days after sowing by which time each plant had at least three fully expanded trifoliolate leaves. Leaf water status and plant growth were measured through destructive samples when 80% and 90% of the estimated plant available water (PAW) was depleted and at plant death, while PAW depletion, node growth and leaf survival were monitored at 2–3 day intervals until the last plants died (61 days after water was withheld). In pure stand, the rate of PAW depletion was initially slowest in cowpea despite its much larger leaf area, and fastest in soybean. Node growth was most sensitive in cowpea, ceasing at 65% PAW depletion compared with 85% PAW depletion in pigeonpea and soybean, so that the latter two species produced relatively more nodes after water was withheld. However, senescence of the lower leaves was most rapid in soybean and slowest in cowpea. Cowpea and pigeonpea extracted almost all PAW and died an average 18 days and 14 days, respectively, after maximum PAW depletion. In contrast, soybean died before 90% of PAW was depleted and so in pure stand used less water. There were otherwise only minor differences between the species combinations in the timing and maximum level of PAW depletion. The ability of cowpea and pigeonpea to maintain leaf water status above lethal levels for longer was achieved through different means. Cowpea relied primarily on dehydration avoidance and maintained tissue water status higher for longer, whereas pigeonpea demonstrated greater dehydration tolerance. While significant levels of osmotic adjustment (OA) were identified in soybean and pigeonpea, OA appeared to be of limited benefit to leaf survival in soybean. Pigeonpea invested significantly more total dry matter (TDM) in roots than either cowpea or soybean. Cowpea survived longest in pure stand whereas pigeonpea and soybean survived shortest in pure stand, suggesting that the dehydration avoidance response of cowpea was more effective in competition with like plants whereas the dehydration tolerance strategies of pigeonpea and soybean were least effective when competing against like plants. On average, TDM per plant ranked in the order cowpea > soybean > pigeonpea, largely reflecting initial differences in plant size when water was withheld. However, there was an inverse relation between TDM of a species and that of its competitor, so that in effect, water not used by a given plant to produce TDM was used by its competitor and there were no differences in TDM production per tube. Publisher: CSIRO Format: application/pdf Other identifier: Likoswe, A.A., and Lawn, Bob (2008) Response to terminal water deficit stress of cowpea, pigeonpea, and soybean in pure stand and in competition. Australian Journal of Agricultural Research, 59 (1). pp. 27-37. ISSN 1836-5795
2009-01-01
We developed a general trace element model called Tracey to simulate dynamically the possible accumulation of radionuclides as a result of an long-term radioactive contamination of groundwater in terrestrial ecosystems. The overall objectives of the study are to: 1) Develop and evaluate a multi-compartmental model that dynamically simulates the transport and accumulation of a radionuclide in the soil-plant system at a time scale relevant for risk assessment of nuclear fuel waste. And 2) Asses the possible accumulation of radionuclide in terrestrial ecosystems due to an eventual long-term continuous radioactive groundwater contamination. Specific objectives were to assess: - The proportion of the contamination accumulated and where it is stored in the ecosystem. - The importance of the plant uptake approach for accumulation of radionuclides. - The most important ... >>
Full Text Available.BackgroundMuscle soreness and decreased performance often follow a bout of high-intensity exercise. By reducing these effects, an athlete can train more frequently and increase long-term performance. The purpose of this study is to examine whether a high-potency, black tea extract (BTE) alters the delayed onset muscle soreness (DOMS), oxidative stress, inflammation, and cortisol (CORT) responses to high-intensity anaerobic exercise.MethodsCollege-age males (N = 18) with 1+ yrs of weight training experience completed a double-blind, placebo-controlled, crossover study. Subjects consumed the BTE (1,760 mg BTE·d-1) or placebo (PLA) for 9 days. Each subject completed two testing sessions (T1 & T2), which occurred on day 7 of the intervention. T1 & T2 consisted of a 30 s Wingate Test plus eight 10 s intervals. Blood samples were obtained before, 0, 30 & 60 min following the interval sessions and were used to analyze the total to oxidized glutathione ratio (GSH:GSSG), 8-isoprostane (8-iso), CORT, and interleukin 6 (IL-6) secretion. DOMS was recorded at 24 & 48 h post-test using a visual analog scale while BTE or PLA continued to be administered. Significance was set at P < 0.05.ResultsCompared to PLA, BTE produced significantly higher average peak power (P = 0.013) and higher average mean power (P = 0.067) across nine WAnT intervals. BTE produced significantly lower DOMS compared to PLA at 24 h post test (P < 0.001) and 48 h post test (P < 0.001). Compared to PLA, BTE had a slightly higher GSH:GSSG ratio at baseline which became significantly higher at 30 and 60 min post test (P < 0.002). AUC analysis revealed BTE to elicit significantly lower GSSG secretion (P = 0.009), significantly higher GSH:GSSG ratio (P = 0.001), and lower CORT secretion (P = 0.078) than PLA. AUC analysis did not reveal a significant difference in total IL-6 response (P = 0.145) between conditions.ConclusionsConsumption of theaflavin-enriched black tea extract led to improved recovery and a reduction in oxidative stress and DOMS responses to acute anaerobic intervals. An improved rate of recovery can benefit all individuals engaging in high intensity, anaerobic exercise as it facilitates increased frequency of exercise.
BackgroundMuscle soreness and decreased performance often follow a bout of high-intensity exercise. By reducing these effects, an athlete can train more frequently and increase long-term...Full Text Available
Full Text Available.BackgroundThe CoAct (Cocreating Activity) study is investigating a novel lifestyle intervention, aimed at the working population, with daily activity monitoring and distance counselling via telephone and secure web messages. The main purpose of this study is to evaluate the effectiveness of lifestyle counselling on the level of physical activity in an occupational health setting. The purposes include also analysing the potential effects of changes in physical activity on productivity at work and sickness absence, and healthcare costs. This article describes the design of the study and the participant flow until and including randomization.Methods/DesignCoAct is a randomised controlled trial with two arms: a control group and intervention group with daily activity monitoring and distance counselling. The intervention focuses on lifestyle modification and takes 12 months. The study population consists of volunteers from 1100 eligible employees of a Finnish insurance company. The primary outcomes of this study are change in physical activity measured in MET minutes per week, work productivity and sickness absence, and healthcare utilisation. Secondary outcomes include various physiological measures. Cost-effectiveness analysis will also be performed. The outcomes will be measured by questionnaires at baseline, after 6, 12, and 24 months, and sickness absence will be obtained from the employer's registers.DiscussionNo trials are yet available that have evaluated the effectiveness of daily physical activity monitoring and distance counselling in an occupational health setting over a 12 month period and no data on cost-effectiveness of such intervention are available.Trial RegistrationClinicalTrials.gov identifier: NCT00994565
BackgroundThe CoAct (Cocreating Activity) study is investigating a novel lifestyle intervention, aimed at the working population, with daily activity monitoring and distance counselling...Full Text Available
2010-01-01
The objective of this study was to determine the effect of body position, chest wrap, and sedation on functional residual capacity (FRC) in 6 healthy dogs. Functional residual capacity was determined...Full Text Available
2010-01-01
Full Text Available.The objective of this study was to determine the effect of body position, chest wrap, and sedation on functional residual capacity (FRC) in 6 healthy dogs. Functional residual capacity was determined by helium dilution (re-breathing) whilst in different clinically relevant conditions. These conditions included the standing (sternal) and lateral positions in unsedated dogs and then again both standing and lateral following chest bandaging, and sedation with acepromazine, IV and butorphanol, IV. The mean FRC at each measurement point was determined, as was the change in FRC (delta FRC) from one measurement point to another. Analysis of variance (ANOVA) with repeated measures with Fisher’s LSD post hoc test was used to evaluate the effect of interventions. The differences in delta FRC were evaluated using a t-test or Wilcoxon rank-sum test. P < 0.05 was considered significant. The mean FRC at baseline, defined as standing, unsedated and unwrapped, was 75.3 ± 23.8 mL/kg. Body position or sedation had the most profound effect on FRC with right lateral recumbency lowering FRC by a median of 20.4 mL/kg and sedation lowering FRC by a median of 19.8 mL/kg. Common clinical procedures and positioning result in lowered FRC in healthy deep-chested dogs. In critically ill or injured dogs, the iatrogenic loss of FRC through chest bandaging, sedation, or body position may be clinically relevant.
The Savannah River Site`s Groundwater Monitoring Program: Fourth quarter 1991
1992-06-02
The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site`s (SRS) Groundwater Monitoring Program. During fourth quarter 1991, EPD/EMS conducted extensive sampling of monitoring wells. EPD/EMS established two sets of criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead, they aid personnel in sample scheduling, interpretation of data, and trend identification. Beginning in 1991, the flagging criteria are based on EPA drinking water standards and method detection limits. A detailed explanation of the current flagging criteria is presented in the Flagging Criteria section of this document. Analytical results from fourth quarter 1991 are listed in this report.
The Savannah River Site's Groundwater Monitoring Program: Fourth quarter 1991
1992-06-02
The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site's (SRS) Groundwater Monitoring Program. During fourth quarter 1991, EPD/EMS conducted extensive sampling of monitoring wells. EPD/EMS established two sets of criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead, they aid personnel in sample scheduling, interpretation of data, and trend identification. Beginning in 1991, the flagging criteria are based on EPA drinking water standards and method detection limits. A detailed explanation of the current flagging criteria is presented in the Flagging Criteria section of this document. Analytical results from fourth quarter 1991 are listed in this report.
The DESY RF driven H- volume source
1998-01-01
Since 1994 an RF driven H- volume source has been operated in the DESY source test stand. In 1995 the source was operated successfully as injector for LINAC III and DESY III. The source is planned as a Cs free low emittance replacement of the magnetron. H- sources for HERA have to run for long uninterrupted periods (300 days) with a low duty factor (0.01%) and a high reliability. New Al2O3 ceramic antenna constructions are presented in order to improve the antenna lifetime. Recent measurements have demonstrated H- currents of up to 80mA in our uncesiated volume source. This was possible due to a negative bias of the collar, a tantalum coating on the collar inside and an optimization of collar and extraction geometry
Tai Chi for osteopenic women: design and rationale of a pragmatic randomized controlled trial
Full Text Available.BackgroundPost-menopausal osteopenic women are at increased risk for skeletal fractures. Current osteopenia treatment guidelines include exercise, however, optimal exercise regimens for attenuating bone mineral density (BMD) loss, or for addressing other fracture-related risk factors (e.g. poor balance, decreased muscle strength) are not well-defined. Tai Chi is an increasingly popular weight bearing mind-body exercise that has been reported to positively impact BMD dynamics and improve postural control, however, current evidence is inconclusive. This study will determine the effectiveness of Tai Chi in reducing rates of bone turnover in post-menopausal osteopenic women, compared with standard care, and will preliminarily explore biomechanical processes that might inform how Tai Chi impacts BMD and associated fracture risks.Methods/DesignA total of 86 post-menopausal women, aged 45-70y, T-score of the hip and/or spine -1.0 and -2.5, have been recruited from primary care clinics of a large healthcare system based in Boston. They have been randomized to a group-based 9-month Tai Chi program plus standard care or to standard care only. A unique aspect of this trial is its pragmatic design, which allows participants randomized to Tai Chi to choose from a pre-screened list of community-based Tai Chi programs. Interviewers masked to participants' treatment group assess outcomes at baseline and 3 and 9 months after randomization. Primary outcomes are serum markers of bone resorption (C-terminal cross linking telopeptide of type I collagen), bone formation (osteocalcin), and BMD of the lumbar spine and proximal femur (dual-energy X-ray absorptiometry). Secondary outcomes include health-related quality-of-life, exercise behavior, and psychological well-being. In addition, kinetic and kinematic characterization of gait, standing, and rising from a chair are assessed in subset of participants (n = 16) to explore the feasibility of modeling skeletal mechanical loads and postural control as mediators of fracture risk.DiscussionResults of this study will provide preliminary evidence regarding the value of Tai Chi as an intervention for decreasing fracture risk in osteopenic women. They will also inform the feasibility, value and potential limitations related to the use of pragmatic designs for the study of Tai Chi and related mind-body exercise. If the results are positive, this will help focus future, more in-depth, research on the most promising potential mechanisms of action identified by this study.Trial registrationThis trial is registered in Clinical Trials.gov, with the ID number of NCT01039012.
Tai Chi for osteopenic women: design and rationale of a pragmatic randomized controlled trial
BackgroundPost-menopausal osteopenic women are at increased risk for skeletal fractures. Current osteopenia treatment guidelines include exercise, however, optimal exercise regimens...Full Text Available
Systems in Development: Motor Skill Acquisition Facilitates 3D Object Completion
2010-01-01
How do infants learn to perceive the backs of objects that they see only from a limited viewpoint? Infants’ 3D object completion abilities emerge in conjunction with developing motor...Full Text Available
Systems in Development: Motor Skill Acquisition Facilitates 3D Object Completion
2010-01-01
Full Text Available.How do infants learn to perceive the backs of objects that they see only from a limited viewpoint? Infants’ 3D object completion abilities emerge in conjunction with developing motor skills—independent sitting and visual-manual exploration. Twenty-eight 4.5- to 7.5-month-old infants were habituated to a limited-view object and tested with volumetrically complete and incomplete (hollow) versions of the same object. Parents reported infants’ sitting experience, and infants’ visual-manual exploration of objects was observed in a structured play session. Infants’ self-sitting experience and visual-manual exploratory skills predicted looking to the novel, incomplete object on the habituation task. Further analyses revealed that self-sitting facilitated infants’ visual inspection of objects while they manipulated them. The results are framed within a developmental systems approach, wherein infants’ sitting skill, multimodal object exploration, and object knowledge are linked in developmental time.
Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
2010-01-01
Remineralization of minor enamel defects is a normal physiological process that is well known to clinicians and researchers in dentistry and oral biology. This process can be facilitated by various...Full Text Available
Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
2010-01-01
Full Text Available.Remineralization of minor enamel defects is a normal physiological process that is well known to clinicians and researchers in dentistry and oral biology. This process can be facilitated by various dietary and oral hygiene procedures and may also concern dentin caries lesions. Dental caries is reversible if detected and treated sufficiently early. Habitual use of xylitol, a sugar alcohol of the pentitol type, can be associated with significant reduction in caries incidence and with tooth remineralization. Other dietary polyols that can remarkably lower the incidence of caries include erythritol which is a tetritol-type alditol. Based on known molecular parameters of simple dietary alditols, it is conceivable to predict that their efficacy in caries prevention will follow the homologous series, that is, that the number of OH-groups present in the alditol molecule will determine the efficacy as follows: erythritol ≥ xylitol > sorbitol. The possible difference between erythritol and xylitol must be confirmed in future clinical trials.
Full Text Available.BackgroundMalnutrition is a common consequence of disease in older patients. Both in hospital setting and in community setting oral nutritional support has proven to be effective. However, cost-effectiveness studies are scarce. Therefore, the aim of our study is to investigate the effectiveness and cost-effectiveness of transmural nutritional support in malnourished elderly patients, starting at hospital admission until three months after discharge.MethodsThis study is a randomized controlled trial. Patients are included at hospital admission and followed until three months after discharge. Patients are eligible to be included when they are ≥ 60 years old and malnourished according to the following objective standards: Body Mass Index (BMI in kg/m2) < 20 and/or ≥ 5% unintentional weight loss in the previous month and/or ≥ 10% unintentional weight loss in the previous six months. We will compare usual nutritional care with transmural nutritional support (energy and protein enriched diet, two additional servings of an oral nutritional supplement, vitamin D and calcium supplementation, and consultations by a dietitian). Each study arm will consist of 100 patients. The primary outcome parameters will be changes in activities of daily living (determined as functional limitations and physical activity) between intervention and control group. Secondary outcomes will be changes in body weight, body composition, quality of life, and muscle strength. An economic evaluation from a societal perspective will be conducted alongside the randomised trial to evaluate the cost-effectiveness of the intervention in comparison with usual care.ConclusionIn this randomized controlled trial we will evaluate the effect of transmural nutritional support in malnourished elderly patients after hospital discharge, compared to usual care. Primary endpoints of the study are changes in activities of daily living, body weight, body composition, quality of life, and muscle strength. An economic evaluation will be performed to evaluate the cost-effectiveness of the intervention in comparison with usual care.Trial registrationNetherlands Trial Register (ISRCTN29617677, registered 14-Sep-2005)
BackgroundMalnutrition is a common consequence of disease in older patients. Both in hospital setting and in community setting oral nutritional support has proven to be effective....Full Text Available
Parkinson's Disease; Severe Gait Disorders With Freezing; No Dementia
Site Selection for the Salt Disposition Facility at the Savannah River Site
2000-11-15
A site selection study was conducted to identify a suitable location for the construction and operation of a new Salt Disposition Facility (SDF) at the Savannah River Site (SRS). The facility to be sited is a single processing facility and support buildings that could house either of three technology alternatives being developed by the High Level Waste Systems Engineering Team: Small Tank Tetraphenylborate Precipitation, Crystalline Silicotitanate Non-Elutable Ion Exchange or Caustic Side Solvent Extraction. A fourth alternative, Direct Disposal in grout, is not part of the site selection study because a location has been identified that is unique to this technology (i.e., Z-Area). Facility site selection at SRS is a formal, documented process that seeks to optimize siting of new facilities with respect to facility-specific engineering requirements, sensitive environmental resources, and applicable regulatory requirements. In this manner, the prime objectives of cost minimization, environmental protection, and regulatory compliance are achieved. The results from this geotechnical characterization indicated that continued consideration be given to Site B for the proposed SDF. Suitable topography, the lack of surface hydrology and floodplain issues, no significant groundwater contamination, the presence of minor soft zones along the northeast portion of footprint, and no apparent geological structure in the Gordon Aquitard support this recommendation.
Present status of the 972 MHz RF test-stand 2006
2006-01-01
A 972 MHz Klystron (tube no.3) and the improved Klystron oil tank was installed at the 972 MHz RF test stand, and has been confirmed the sufficient performance. The high power RF test of the first ACS module has been carried out from May 2006. The 972 MHz RF test stand has been operated for about seventy hours without any troubles. (author)
Potential Role of Thymosin-α1 Adjuvant Therapy for Glioblastoma
2009-01-01
Glioblastomas are high-grade, malignant CNS neoplasms that are nearly always fatal within 12 months of diagnosis. Immunotherapy using proinflammatory cytokines such as IL-2 or IL-12 may prolong survival...Full Text Available
Potential Role of Thymosin-α1 Adjuvant Therapy for Glioblastoma
2009-01-01
Full Text Available.Glioblastomas are high-grade, malignant CNS neoplasms that are nearly always fatal within 12 months of diagnosis. Immunotherapy using proinflammatory cytokines such as IL-2 or IL-12 may prolong survival with glioblastoma. Thymosin-α1 (Talpha1) is a thymic hormone and immunemodulator that increase IL-2 production and T-cell proliferation. We examined potential therapeutic effects of Talpha1 in experimental in vivo glioblastoma, and characterized Talpha1's anti-tumor effects in vitro. Rar 9L cells (104) were implanted into the right frontal lobe of adult Long Evans rats that were subsequently treated with vehicle, BCNU, Talpha1, or Talpha1+BCNU from postoperative day 6. Talpha1+BCNU significantly lowered tumor burdens, and increased cure rates. In vitro experiments demonstrated that Talpha1 had no direct effect on viability or mitochondrial function, and instead, it increased expression of pro-apoptosis genes, including FasL, FasR and TNFα-R1 (65.89%, 44.08%, and 22.18%, resp.), and increased 9L cell sensitivity to oxidative stress. Moreover, Talpha1 enhanced 9L cell sensitivity to both Granzyme B- and BCNU-mediated killing. The findings suggest that Talpha1 enhances BCNUmediated eradication of glioblastoma in vivo, and that Talpha1 mediates its effects by activating pro-apoptosis mechanisms, rendering neoplastic cells more sensitive to oxidative stress and immune-mediated killing by Granzyme B and chemotherapeutic agents.
Performance of 3.9 GHz SRF cavities at Fermilab's ILCTA()MDB horizontal test stand
2008-01-01
Fermilab is building a cryomodule containing four 3.9 GHz superconducting radio frequency (SRF) cavities for the Free electron LASer in Hamburg (FLASH) facility at the Deutsches Elektronen-SYnchrotron (DESY) laboratory. Before assembling the cavities into the cryomodule, each individual cavity is tested at Fermilab's Horizontal Test Stand (HTS). The HTS provides the capability to test fully-dressed SRF cavities at 1.8 K with high-power pulsed RF in order to verify that the cavities achieve performance requirements under these conditions. The performance at the HTS of the 3.9 GHz cavities built for FLASH is presented here
Performance of 3.9 GHz SRF Cavities at Fermilab's ILCTA-MDB Horizontal Test Stand
2009-01-01
Fermilab is building a cryomodule containing four 3.9 GHz superconducting radio frequency (SRF) cavities for the Free electron LASer in Hamburg (FLASH) facility at the Deutsches Elektronen-SYnchrotron (DESY) laboratory. Before assembling the cavities into the cryomodule, each individual cavity is tested at Fermilab's Horizontal Test Stand (HTS). The HTS provides the capability to test fully-dressed SRF cavities at 1.8 K with high-power pulsed RF in order to verify that the cavities achieve performance requirements under these conditions. The performance at the HTS of the 3.9 GHz cavities built for FLASH is presented here
Outcome of coronary plaque burden: a 10-year follow-up of aggressive medical management
Full Text Available.BackgroundThe effect of aggressive medical therapy on quantitative coronary plaque burden is not generally known, especially in ethnic Chinese.AimsWe reasoned that Cardiac CT could conveniently quantify early coronary atherosclerosis in our patient population, and hypothesized that serial observation could differentiate the efficacy of aggressive medical therapy regarding progression and regression of the atherosclerotic process, as well as evaluating the additional impact of life-style modification and the relative effects of the application of statin therapy.MethodsWe employed a standardized Cardiac CT protocol to serially scan 113 westernized Hong Kong Chinese individuals (64 men and 49 women) with Chest Pain and positive coronary risk factors. In all cases included for this serial investigation, subsequent evaluation showed no significantly-obstructive coronary disease by functional studies and angiography. After stringent risk factor modification, including aggressive statin therapy to achieve LDL-cholesterol lowering conforming to N.C.E.P. ATP III guidelines, serial CT scans were performed 1-12 years apart for changes in coronary artery calcification (CAC), using the Agatston Score (AS) for quantification.ResultsAt baseline, the mean AS was 1413.6 for males (mean age 54.4 years) and 2293.3 for females (mean age 62.4 years). The average increase of AS in the entire study population was 24% per year, contrasting with 16.4% per year on strict risk factor modification plus statin therapy, as opposed to 33.2% per year for historical control patients (p < 0.001). Additionally, 20.4% of the 113 patients demonstrated decreasing calcium scores. Medical therapy also yielded a remarkably low adverse event rate during the follow-up period --- 2 deaths, 2 strokes and only 1 case requiring PCI.ConclusionsThis study revealed that aggressive medical therapy can positively influence coronary plaque aiding in serial regression of calcium scores.
Outcome of coronary plaque burden: a 10-year follow-up of aggressive medical management
BackgroundThe effect of aggressive medical therapy on quantitative coronary plaque burden is not generally known, especially in ethnic Chinese.AimsWe...Full Text Available
Neurofeedback and biofeedback with 37 migraineurs: a clinical outcome study
Full Text Available.BackgroundTraditional peripheral biofeedback has grade A evidence for effectively treating migraines. Two newer forms of neurobiofeedback, EEG biofeedback and hemoencephalography biofeedback were combined with thermal handwarming biofeedback to treat 37 migraineurs in a clinical outpatient setting.Methods37 migraine patients underwent an average of 40 neurofeedback sessions combined with thermal biofeedback in an outpatient biofeedback clinic. All patients were on at least one type of medication for migraine; preventive, abortive or rescue. Patients kept daily headache diaries a minimum of two weeks prior to treatment and throughout treatment showing symptom frequency, severity, duration and medications used. Treatments were conducted an average of three times weekly over an average span of 6 months. Headache diaries were examined after treatment and a formal interview was conducted. After an average of 14.5 months following treatment, a formal interview was conducted in order to ascertain duration of treatment effects.ResultsOf the 37 migraine patients treated, 26 patients or 70% experienced at least a 50% reduction in the frequency of their headaches which was sustained on average 14.5 months after treatments were discontinued.ConclusionsAll combined neuro and biofeedback interventions were effective in reducing the frequency of migraines with clients using medication resulting in a more favorable outcome (70% experiencing at least a 50% reduction in headaches) than just medications alone (50% experience a 50% reduction) and that the effect size of our study involving three different types of biofeedback for migraine (1.09) was more robust than effect size of combined studies on thermal biofeedback alone for migraine (.5). These non-invasive interventions may show promise for treating treatment-refractory migraine and for preventing the progression from episodic to chronic migraine.
Neurofeedback and biofeedback with 37 migraineurs: a clinical outcome study
BackgroundTraditional peripheral biofeedback has grade A evidence for effectively treating migraines. Two newer forms of neurobiofeedback, EEG biofeedback and hemoencephalography...Full Text Available
NDCX-II project commencing at LBNL
2009-01-01
Earlier this year, the U.S. Department of Energy Office of Fusion Energy Sciences approved the NDCX-II project, a second-generation Neutralized Drift Compression eXperiment. NDCX-II is a collaborative effort of scientists and engineers from Lawrence Berkeley National Laboratory (LBNL), Lawrence Livermore National Laboratory (LLNL), and the Princeton Plasma Physics Laboratory (PPPL), in a formal collaboration known as the Virtual National Laboratory for Heavy Ion Fusion Science (HIFS-VNL). Supported by $11 M of funding from the American Recovery and Reinvestment Act, construction at LBNL commenced in July of 2009, with completion anticipated in March of 2012. Applications of this facility will include studies of: the basic physics of the poorly understood 'warm dense matter' regime of temperatures around 1 eV and densities near solid, using uniform, volumetric ion ... >>
Level-adjustment in millimeter range of concrete floor casting
2005-01-01
Trial of surface level control in millimetre range on concrete floor has been applied in the accelerator tunnel at SCSS test accelerator, which is under construction at SPring-8 site. SCSS project is aiming at generating X-ray laser, in which very tight alignment on accelerator component, as low as 8 micron-meter transverse for 80 m undulator line, is required. To do this, we introduced various new techniques: (1) HeNe laser in line alignment system, (2) ceramic stable stand for BPMs, and (3) a robotic machine to grind the concrete floor into a very flat surface with 50 micron-meter accuracy. To match with those techniques, we are trying to find a suitable way for casting to minimize the level error less than +-5 mm. (author)
Ionizing radiation detection meter systems usability evaluation. Technical memorandum
2002-01-01
In support of the Canadian Forces Nuclear Detection, Identification and Dosimetry project a usability trial of three Ionizing Radiation Detection Meter Systems (IRDMS) was conducted 18-22 June 2001 at Connaught Ranges. The systems evaluated: System 1: ANPDR 77 Operational System with PDR 77 Alpha/Beta probes and GPS (Global Positioning System) Training System. System 2: ADM 300C Operational System with ABP 100 Alpha/Beta probes and GPS Training System, and System 3: RAM R200 Operational System with PA 100M and RG12 Alpha/Beta probes and GPS Training System. Twelve military personnel (Private to Captain) determined compliance with the bid evaluation criteria. The counter-balanced study, based on a Latin square design, was divided into two assessment phases, an operational phase and a training system phase, which rotated three groups (of four participants each) ... >>
Full Text Available.BackgroundThere are growing reasons to use both information and communication functions of learning technologies as part of clinical education, but the literature offers few accounts of such implementations or evaluations of their impact. This paper details the process of implementing a blend of online and face-to-face learning and teaching in a clinical education setting and it reports on the educational impact of this innovation.MethodsThis study designed an online community to complement a series of on-site workshops and monitored its use over a semester. Quantitative and qualitative data recording 43 final-year medical students' and 13 clinical educators' experiences with this blended approach to learning and teaching were analysed using access, adoption and quality criteria as measures of impact.ResultsThe introduction of the online community produced high student ratings of the quality of learning and teaching and it produced student academic results that were equivalent to those from face-to-face-only learning and teaching. Staff had mixed views about using blended learning.ConclusionsProjects such as this take skilled effort and time. Strong incentives are required to encourage clinical staff and students to use a new mode of communication. A more synchronous or multi-channel communication feedback system might stimulate increased adoption. Cultural change in clinical teaching is also required before clinical education can benefit more widely from initiatives such as this.
BackgroundThere are growing reasons to use both information and communication functions of learning technologies as part of clinical education, but the literature offers few accounts...Full Text Available
International society of sports nutrition position stand: caffeine and performance
Position Statement: The position of The Society regarding caffeine supplementation and sport performance is summarized by the following seven points: 1.) Caffeine is effective for enhancing sport performance...Full Text Available
International society of sports nutrition position stand: caffeine and performance
Full Text Available.Position Statement: The position of The Society regarding caffeine supplementation and sport performance is summarized by the following seven points: 1.) Caffeine is effective for enhancing sport performance in trained athletes when consumed in low-to-moderate dosages (~3-6 mg/kg) and overall does not result in further enhancement in performance when consumed in higher dosages (≥ 9 mg/kg). 2.) Caffeine exerts a greater ergogenic effect when consumed in an anhydrous state as compared to coffee. 3.) It has been shown that caffeine can enhance vigilance during bouts of extended exhaustive exercise, as well as periods of sustained sleep deprivation. 4.) Caffeine is ergogenic for sustained maximal endurance exercise, and has been shown to be highly effective for time-trial performance. 5.) Caffeine supplementation is beneficial for high-intensity exercise, including team sports such as soccer and rugby, both of which are categorized by intermittent activity within a period of prolonged duration. 6.) The literature is equivocal when considering the effects of caffeine supplementation on strength-power performance, and additional research in this area is warranted. 7.) The scientific literature does not support caffeine-induced diuresis during exercise, or any harmful change in fluid balance that would negatively affect performance.
Implications of Genetic Polymorphisms in Inflammation-Induced Atherosclerosis
Inflammation is the mainstay of atherosclerosis and is an important governing factor at all stages of the disease process from lesion formation to plaque build-up and final end-stage rupture and thrombosis....Full Text Available
Implications of Genetic Polymorphisms in Inflammation-Induced Atherosclerosis
Full Text Available.Inflammation is the mainstay of atherosclerosis and is an important governing factor at all stages of the disease process from lesion formation to plaque build-up and final end-stage rupture and thrombosis. An overview of the numerous clinico-epidemiological studies on the association between inflammatory gene polymorphisms and Cardiovascular disease (CVD) and its co-morbidities have shown that the risk associated with any single genotype is modest while the haplotypes, especially those defined on the basis of tag-SNP approach, have better coverage of the gene and show moderately higher impact on disease risk. Nevertheless, even these associations have been inconsistent with low cross-race repeatability. This has been attributed to many plausible causes such as clinical heterogeneity, sample selection criteria, variable genetic landscapes across different ethnic groups, confounding effect of co-morbidities etc. On the other hand, unbiased studies such as the family-based linkage and case-control based associations that have taken into account, thousands of genotypic markers spanning the whole genome, have had the ability to identify novel genetic loci for coronary artery disease. These studies have shown that many inflammatory genes are involved in the regulation of specific biomarkers of inflammation that collectively contribute to the disease-associated risk. In addition, there appears to be considerable cross talk between the different biochemical and metabolic processes. Therefore, consideration of all these factors can build towards an ‘atherosclerotic bionetwork’ that can refine our quest for developing a robust risk stratification tool for cardiovascular disease.
High heat flux test with HIP-bonded Cu/SS mock-ups for the ITER first wall
2008-01-01
In order to verify the integrity of the first wall (FW) of the International Thermonuclear Experimental Reactor (ITER), the fabricated Cu/SS mock-ups were tested with an e-beam facility, JEBIS (JAEA (Japan Atomic Energy Agency) Electron Beam Irradiation Stand). The Cu/SS mock-ups were joined with CuCrZr as the heat sink material among Cu alloys and 316L austenitic stainless steel (SS316L) as the structural material. Hot isostatic pressing (HIP) was used as a manufacturing method at 1050 deg. C and 100 MPa for 2 h. The high heat flux (HHF) tests were performed for two Cu/SS mock-ups under different heat flux conditions (5 MW/m2 and 3.2 MW/m2) and duration times, which were determined from the preliminary analysis with ANSYS-10. The temperature results from the test showed good agreement with the analysis results, and the fatigue lifetime was evaluated ... >>
Hanford Works monthly report, February 1949
1949-03-18
This document details activities of the Hanford Works during the month of February 1949. (JL)
Hanford Laboratories monthly activities report, July 1963
1963-08-15
This is the monthly report for the Hanford Laboratories Operation, July 1963. Metallurgy, reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, visits, biology operation, physics and instrumentation research, and employee relations are discussed.
Hanford Laboratories monthly activities report, January 1963
1963-02-15
This is the monthly report for the Hanford Laboratories Operation January 1963. Reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, biology operation, physics and instrumentation research, operations research and synthesis, programming, and radiation protection operation are discussed.
Hanford Laboratories Operation monthly activities report, September 1960
1960-10-15
This is the monthly report for the Hanford Laboratories Operation, October, 1960. Metallurgy, reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, visits, biology operation, physics and instrumentation research, and employee relations are discussed.
Hanford Laboratories Operation monthly activities report, November 1959
1959-12-15
This is the monthly report for the Hanford Laboratories Operation, November 1959. Metallurgy, reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, visits, biology operation, physics and instrumentation research, and employee relations are discussed.
Hanford Laboratories Operation monthly activities report, June 1961
1961-07-15
The monthly report for the Hanford Laboratories Operation, June 1961. Reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, biology operation, and physics and instrumentation research, operations research and synthesis operation, programming, laboratory auxiliaries operation, and professional placement and relations practices are discussed.
Hanford Laboratories Operation monthly activities report, July 1962
1962-08-15
This is the monthly report for the Hanford Laboratories Operation July 1962. Reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, biology operation, physics and instrumentation research, operations research and synthesis, programming, and radiation protection operation are discussed.
Hanford Laboratories Operation monthly activities report, July 1960
1960-08-15
This document presents a summary of work and progress at the Hanford Engineer Works for July, 1969. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and separation sections. The Engineering Department`s section summarizes work for the Technical, Design, and Project sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical, Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Services Departments have sections presenting their monthly statistics, work, progress, and summaries.
Hanford Laboratories Operation monthly activities report, January 1961
1961-02-15
This is the monthly report for the Hanford Laboratories Operation, January 1961. Metallurgy, reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, visits, biology operation, physics and instrumentation research, and employee relations are discussed.
Hanford Laboratories Operation monthly activities report, December 1962
1963-01-15
This is the monthly report for the Hanford Laboratories Operation, December 1962. Metallurgy, reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, visits, biology operation, physics and instrumentation research, and employee relations are discussed.
Hanford Laboratories Operation monthly activities report, December 1961
1962-01-15
The monthly report for the Hanford Laboratories Operation, May 1961. Reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, biology operation, and physics and instrumentation research, operations research and synthesis operation, programming, laboratory auxiliaries operation, and technical administration operation are discussed.
Hanford Atomic Products Operation monthly report, March 1954
1954-04-23
This document presents a summary of work and progress at the Hanford Engineer Works for March 1954. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The Manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and Separation sections. The Engineering Department`s section summaries work for the Technical, Design, and Project Sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical, Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Service departments have sections presenting their monthly statistics, work, progress, and summaries.
Fourth DOE Natural Phenomena Hazards Mitigation Conference: Proceedings. Volume 1
1993-12-31
This conference allowed an interchange in the natural phenomena area among designers, safety professionals, and managers. The papers presented in Volume I of the proceedings are from sessions I - VIII which cover the general topics of: DOE standards, lessons learned and walkdowns, wind, waste tanks, ground motion, testing and materials, probabilistic seismic hazards, risk assessment, base isolation and energy dissipation, and lifelines and floods. Individual papers are indexed separately. (GH)
Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets
Full Text Available.BackgroundSolving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve overall performance. The Cell Broadband Engine (CBE), a heterogeneous multi-core processor, provides power-efficient and cost-effective high-performance computing. One application area is image analysis and visualisation, in particular registration of 2D cross-sections into 3D image datasets. Such techniques can be used to put different image modalities into spatial correspondence, for example, 2D images of histological cuts into morphological 3D frameworks.ResultsWe evaluate the CBE-driven PlayStation 3 as a high performance, cost-effective computing platform by adapting a multimodal alignment procedure to several characteristic hardware properties. The optimisations are based on partitioning, vectorisation, branch reducing and loop unrolling techniques with special attention to 32-bit multiplies and limited local storage on the computing units. We show how a typical image analysis and visualisation problem, the multimodal registration of 2D cross-sections and 3D datasets, benefits from the multi-core based implementation of the alignment algorithm. We discuss several CBE-based optimisation methods and compare our results to standard solutions. More information and the source code are available from http://cbe.ipk-gatersleben.de.ConclusionsThe results demonstrate that the CBE processor in a PlayStation 3 accelerates computational intensive multimodal registration, which is of great importance in biological/medical image processing. The PlayStation 3 as a low cost CBE-based platform offers an efficient option to conventional hardware to solve computational problems in image processing and bioinformatics.
Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets
BackgroundSolving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve...Full Text Available
Effects of a 14-month low-cost maintenance training program in patients with chronic systolic heart failure: a randomized study
2009-01-01
BACKGROUND: Exercise training is known to be beneficial in chronic heart failure (CHF) patients but there is a lack of studies following patient groups for longer duration with maintenance training programs to defer deconditioning. METHODS: Study base consisted of all patients diagnosed with CHF in a 3-year period. Sixty-six patients with systolic CHF (ejection fraction
Development of a radioactive ion beam test stand at LBNL
1999-01-01
For the on-line production of a 14O+ ion beam, an integrated target-transfer line ion source system is now under development at LBNL. 14O is produced in the form of CO in a high temperature carbon target using a 20 MeV 3He beam from the LBNL 88'' Cyclotron via the reaction 12C(3He,n)14O. The neutral radioactive CO molecules diffuse through an 8 m room temperature stainless steel line from the target chamber into a cusp ion source. The molecules are dissociated, ionized and extracted at energies of 20 to 30 keV and mass separated with a double focusing bending magnet. The different components of the setup are described. The release and transport efficiency for the CO molecules from the target through the transfer line was measured for various target temperatures. The ion beam transport ... >>
2008-01-01
A high-brightness and low-divergence neutral beam is obtained for a Zeeman polarimetry of edge plasmas on JT-60U. The electron density and the pitch angle of the magnetic field line, thus the plasma current density distribution, can be measured by the Zeeman polarimetry using the lithium beam. A thermionic ion source heated by an electron beam is developed in order to obtain the ion beam current extraction over 10 mA. The beam optics is designed after detailed numerical simulation taking the space charge effects into account because a low-divergence angle of the neutral lithium beam leads to a narrow spectrum of the beam emission. It is also necessary to keep the beam radius small for good spatial resolution due to a long beam line of 6.5 m. The newly developed ion gun is operated on a test stand which simulates the diagnostic arrangement on JT-60U. The ion beam current of 10 mA at a beam ... >>
Data acquisition system of 324 MHz klystron test stand at J-PARC LINAC
2006-01-01
The J-PARC (Japan Proton Accelerator Research Complex) Linac consists of RFQ, DTL1-3 and SDTL1-15. They are driven by 324 MHz klystrons. We measured RF characteristics of 24 klystrons, and obtained various parameters by klystron high power tests at test stations. In this paper, we report the data acquisition system used by this high power tests. (author)
Cyborg Scripting Language Advanced Customization
Introduction ................................................................................................................. 11 The Solution Series files.............................................................................................. 13 Reading random files................................................................................................... 17 Reading files sequentially ........................................................................................... 31 Section 2 exercise 1..................................................................................................... 35 Unlocking files ............................................................................................................ 37 Writing and rewriting records ..................................................................................... 39 Deleting records .......................................................................................................... 45 Section summary ......................................................................................................... 49 Section 2 exercise 2.
Correlation Between Strand Stability and Magnet Performance
2005-01-01
Magnet programs at BNL, LBNL and FNAL have observed instabilities in high Jc Nb3Sn strands and magnets made from these strands. This paper correlates the strand stability determined from a short sample-strand test to the observed magnet performance. It has been observed that strands that carry high currents at high fields (greater than 10 T) cannot sustain these same currents at low fields (1-3 T) when the sample current is fixed and the magnetic field is ramped. This suggests that the present generation of strand is susceptible to flux jumps (FJ). To prevent flux jumps from limiting stand performance, one must accommodate the energy released during a flux jump. To better understand FJ this work has focused on wire with a given sub-element diameter and shows that one can significantly improve stability by increasing the copper conductivity (higher ... >>
Comparison of CFD and Test Techniques for Cavitation Inception
2009-01-01
Cavitation erosion on centrifugal pump impellers is a one of the fundamental factors that cause performance degradation and life shortening of the pumps. One approach to estimate the expected life of an impeller is to use sheet cavity length on the blade surface. While observing the cavity length is more suitable to accurately predict the impeller damage, it is not readily available in the field or on the test stand. Recently, the prediction of the cavity length by using commercial CFD codes has been tried by several authors. As an alternative to direct measure the cavity length of an impeller, a means of estimating cavity length of an impeller based on the relation of operating NPSH to that of 3% NPSH and inception NPSH was developed by Cooper. Although this method seems to be attractive, it is not easy to accurately estimate the inception NPSH without flow visualization. Some recent ... >>
2010-01-01
Full Text Available.AbstractAs part of a drug discovery programme to discover new treatments for human African trypanosomiasis, recombinant trypanothione reductase from Trypanosoma brucei has been expressed, purified and characterized. The crystal structure was solved by molecular replacement to a resolution of 2.3 Å and found to be nearly identical to the T. cruzi enzyme (root mean square deviation 0.6 Å over 482 Cα atoms). Kinetically, the Km for trypanothione disulphide for the T. brucei enzyme was 4.4-fold lower than for T. cruzi measured by either direct (NADPH oxidation) or DTNB-coupled assay. The Km for NADPH for the T. brucei enzyme was found to be 0.77 μM using an NADPH-regenerating system coupled to reduction of DTNB. Both enzymes were assayed for inhibition at their respective S = Km values for trypanothione disulphide using a range of chemotypes, including CNS-active drugs such as clomipramine, trifluoperazine, thioridazine and citalopram. The relative IC50 values for the two enzymes were found to vary by no more than 3-fold. Thus trypanothione reductases from these species are highly similar in all aspects, indicating that they may be used interchangeably for structure-based inhibitor design and high-throughput screening.
2010-01-01
AbstractAs part of a drug discovery programme to discover new treatments for human African trypanosomiasis, recombinant trypanothione reductase from Trypanosoma brucei...Full Text Available
2005-01-01
The modeling of complex transients in Nuclear Power Plants (NPP) remains a challenging topic for Best Estimate (BE) three-dimensional coupled code computational tools. Nowadays, this technique is extensively used since it allows decreasing conservatism in the calculation models by performing more realistic simulations based on a more precise consideration of multidimensional effects under complex transients in NPPs. This paper represents a contribution to the assessment and validation of coupled code technique through the Kozloduy VVER-1000 pump trip test. The coupled RELAP5/3.3-PARCS/2.6 and DYN3D/3-RELAP5/3.3 code systems are used in simulations. The obtained results are assessed against experimental data and also through the code-to-code comparison. The DYN3D/RELAP5 computational model of VVER-1000 has been developed and adjusted for simulations with ... >>
Commissioning the Front End Test Stand High Performance H- Ion Source at RAL
2009-01-01
The RAL Front End Test Stand (FETS) is being constructed to demonstrate a chopped H- beam of up to 60 mA at 3 MeV with 50 p.p.s. and sufficiently high beam quality for future high-power proton accelerators (HPPA). High power proton accelerators with beam powers in the several megawatt range have many applications including drivers for spallation neutron sources, neutrino factories, waste transmuters and tritium production facilities. The aim of the FETS project is to demonstrate that chopped low energy beams of high quality can be produced and is intended to allow generic experiments exploring a variety of operational conditions. This paper details the first stage of construction- the installation and commissioning of the ion source. Initial performance figures are reported
Commissioning and early operating experience with the Fermilab horizontal test facility
2007-01-01
Fermilab has constructed a facility for testing dressed superconducting radiofrequency (RF) cavities at 1.8 K with high-power pulsed RF. This test stand was designed to test both 9-cell 1.3 GHz TESLA-style cavities and 9-cell 3.9 GHz cavities being built by Fermilab for DESY's TTF-FLASH facility. An overview of the test stand and a description of its initial commissioning is described here
Calibration of the CDF tile-fiber endplug calorimeters using moving radioactive sources
1998-01-01
The use of moving radioactive gamma sources to assess, calibrate and monitor scintillating tile calorimeters is discussed, and the techniques and equipment are described. The capabilities of the technique are illustrated using Cs137 sources with the CDF Endplug Upgrade EM and Hadron calorimeters at testbeams and at a cosmic ray test stand. Source measurements of all the tiles in testbeam modules which are exact replicas of the calorimeters, predict the relative responses of EM towers to 50 GeV positrons and muons, and of Hadron towers to 50 GeV pions, with RMS accuracies of 1.3%, 1.8% and 2.0%, respectively. Source measurements will be used in lieu of testbeam measurements for the initial calibration of all towers in the final calorimeters. Source measurements of single tiles are reproducible to 0.4% and will be used to monitor gain changes of the photomultiplier ... >>
Application of coupled code technique to a safety analysis of a standard MTR research reactor
2009-01-01
Accident analyses in nuclear research reactors have been performed, up to now, using simple computational tools based on conservative physical models. These codes, developed to focus on specific phenomena in the reactor, were widely used for licensing purposes. Nowadays, the advances in computer technology make it possible to switch to a new generation of computational tools that provides more realistic description of the phenomena occurring in a nuclear research reactor. Recent International Atomic Energy Agency (IAEA) activities have emphasized the maturity in using Best Estimate (BE) Codes in the analysis of accidents in research reactors. Indeed, some assessments have already been performed using BE thermal-hydraulic system codes such as RELAP5/Mod3. The challenge today is oriented to the application of coupled code techniques for research reactors safety ... >>
Analysis of reactivity measurements in core physics experiments on full-MOX BWR
2009-01-01
A core physics experimental program FUBILA has been performed to study core physics characteristics of full-MOX BWR cores consisting of high Pu-enriched MOX assemblies for high burnups. The program includes the measurement of reactivity worth, which is essential in operating BWR cores. The reactivity worth is due to the reactivity caused by (1) changes in the in-channel void fraction of assemblies, (2) the insertion of a B4C control blade, (3) Gd2O3-UO2 rods and UO2 rods in assemblies, and (4) the mixing of boron in a moderator related to a stand-by liquid control system. The reactivity worth was measured by the modified neutron source multiplication method using the reactivity worth of a pilot rod as a reference worth. The measured reactivity worth was determined by processing count rates of neutron detectors ... >>
An Investigation into the Cognition Behind Spontaneous String Pulling in New Caledonian Crows
The ability of some bird species to pull up meat hung on a string is a famous example of spontaneous animal problem solving. The “insight” hypothesis claims that this complex behaviour...Full Text Available
An Investigation into the Cognition Behind Spontaneous String Pulling in New Caledonian Crows
Full Text Available.The ability of some bird species to pull up meat hung on a string is a famous example of spontaneous animal problem solving. The “insight” hypothesis claims that this complex behaviour is based on cognitive abilities such as mental scenario building and imagination. An operant conditioning account, in contrast, would claim that this spontaneity is due to each action in string pulling being reinforced by the meat moving closer and remaining closer to the bird on the perch. We presented experienced and naïve New Caledonian crows with a novel, visually restricted string-pulling problem that reduced the quality of visual feedback during string pulling. Experienced crows solved this problem with reduced efficiency and increased errors compared to their performance in standard string pulling. Naïve crows either failed or solved the problem by trial and error learning. However, when visual feedback was available via a mirror mounted next to the apparatus, two naïve crows were able to perform at the same level as the experienced group. Our results raise the possibility that spontaneous string pulling in New Caledonian crows may not be based on insight but on operant conditioning mediated by a perceptual-motor feedback cycle.
Allele Interaction – Single Locus Genetics Meets Regulatory Biology
Full Text Available.BackgroundSince the dawn of genetics, additive and dominant gene action in diploids have been defined by comparison of heterozygote and homozygote phenotypes. However, these definitions provide little insight into the underlying intralocus allelic functional dependency and thus cannot serve directly as a mediator between genetics theory and regulatory biology, a link that is sorely needed.Methodology/Principal FindingsWe provide such a link by distinguishing between positive, negative and zero allele interaction at the genotype level. First, these distinctions disclose that a biallelic locus can display 18 qualitatively different allele interaction sign motifs (triplets of +, – and 0). Second, we show that for a single locus, Mendelian dominance is not related to heterozygote allele interaction alone, but is actually a function of the degrees of allele interaction in all the three genotypes. Third, we demonstrate how the allele interaction in each genotype is directly quantifiable in gene regulatory models, and that there is a unique, one-to-one correspondence between the sign of autoregulatory feedback loops and the sign of the allele interactions.Conclusion/SignificanceThe concept of allele interaction refines single locus genetics substantially, and it provides a direct link between classical models of gene action and gene regulatory biology. Together with available empirical data, our results indicate that allele interaction can be exploited experimentally to identify and explain intricate intra- and inter-locus feedback relationships in eukaryotes.
Allele Interaction – Single Locus Genetics Meets Regulatory Biology
BackgroundSince the dawn of genetics, additive and dominant gene action in diploids have been defined by comparison of heterozygote and homozygote phenotypes. However, these definitions...Full Text Available
A New Chamber for Studying the Behavior of Drosophila
Methods available for quickly and objectively quantifying the behavioral phenotypes of the fruit fly, Drosophila melanogaster, lag behind in sophistication the tools developed for manipulating...Full Text Available
A New Chamber for Studying the Behavior of Drosophila
Full Text Available.Methods available for quickly and objectively quantifying the behavioral phenotypes of the fruit fly, Drosophila melanogaster, lag behind in sophistication the tools developed for manipulating their genotypes. We have developed a simple, easy-to-replicate, general-purpose experimental chamber for studying the ground-based behaviors of fruit flies. The major innovative feature of our design is that it restricts flies to a shallow volume of space, forcing all behavioral interactions to take place within a monolayer of individuals. The design lessens the frequency that flies occlude or obscure each other, limits the variability in their appearance, and promotes a greater number of flies to move throughout the center of the chamber, thereby increasing the frequency of their interactions. The new chamber design improves the quality of data collected by digital video and was conceived and designed to complement automated machine vision methodologies for studying behavior. Novel and improved methodologies for better quantifying the complex behavioral phenotypes of Drosophila will facilitate studies related to human disease and fundamental questions of behavioral neuroscience.
A Demonstration of the Transition from Ready-to-Hand to Unready-to-Hand
The ideas of continental philosopher Martin Heidegger have been influential in cognitive science and artificial intelligence, despite the fact that there has been no effort to analyze these ideas empirically....Full Text Available
A Demonstration of the Transition from Ready-to-Hand to Unready-to-Hand
Full Text Available.The ideas of continental philosopher Martin Heidegger have been influential in cognitive science and artificial intelligence, despite the fact that there has been no effort to analyze these ideas empirically. The experiments reported here are designed to lend empirical support to Heidegger's phenomenology and more specifically his description of the transition between ready-to-hand and unready-to-hand modes in interactions with tools. In experiment 1, we found that a smoothly coping cognitive system exhibits type positively correlated noise and that its correlated character is reduced when the system is perturbed. This indicates that the participant and tool constitute a self-assembled, extended device during smooth coping and this device is disrupted by the perturbation. In experiment 2, we examine the re-organization of awareness that occurs when a smoothly coping, self-assembled, extended cognitive system is perturbed. We found that the disruption is accompanied by a change in attention which interferes with participants' performance on a simultaneous cognitive task. Together these experiments show that a smoothly coping participant-tool system can be temporarily disrupted and that this disruption causes a change in the participant's awareness. Since these two events follow as predictions from Heidegger's work, our study offers evidence for the hypothesized transition from readiness-to-hand to unreadiness-to-hand.
Testing the Effect of Metabolic Rate on DNA Variability at the Intra-Specific Level
We tested the metabolic rate hypothesis (whereby rates of mtDNA evolution are postulated to be mediated primarily by mutagenic by-products of respiration) by examining whether mass-specific metabolic...Full Text Available
Testing the Effect of Metabolic Rate on DNA Variability at the Intra-Specific Level
Full Text Available.We tested the metabolic rate hypothesis (whereby rates of mtDNA evolution are postulated to be mediated primarily by mutagenic by-products of respiration) by examining whether mass-specific metabolic rate was correlated with root-to-tip distance on a set of mtDNA trees for the springtail Cryptopygus antarcticus travei from sub-Antarctic Marion Island.Using Bayesian analyses and a novel application of the comparative phylogenetic method, we did not find significant evidence that contemporary metabolic rates directly correlate with mutation rate (i.e., root-to-tip distance) once the underlying phylogeny is taken into account. However, we did find significant evidence that metabolic rate is dependent on the underlying mtDNA tree, or in other words, lineages with related mtDNA also have similar metabolic rates.We anticipate that future analyses which apply this methodology to datasets with longer sequences, more taxa, or greater variability will have more power to detect a significant direct correlation between metabolic rate and mutation rate. We conclude with suggestions for future analyses that would extend the preliminary approach applied here, in particular highlighting ways to tease apart oxidative stress effects from the effects of population size and/or selection coefficients operating on the molecular evolutionary rate.
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