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Sample records for 5l x70 em

  1. Study of API 5L X70 steel corrosion processes when in contact with some Brazilian soils; Estudo dos processos de corrosao de acos API 5L X70 em contato com alguns dos solos do Brasil

    Jesus, Sergio Luis de

    2007-07-01

    Pipelines, fuel storage tanks and other metallic structures are in permanent contact and exposed to different types of soils, of horizons or layers, or of soil aggressiveness. This interaction may cause expressive damages to the environment and to the planned work. Contamination may occur due to leakage of stored products, splitting during transportation, accidents caused by pipelines without extensive maintenance. The result of these accidents could be, among others, some financial losses. In order to recognize the dynamic interactions between metallic surfaces and the environment it is crucial to have preventive actions and to develop better-applied materials. API steel 5L X70 has been used in structures of low and high pressure with high mechanical strength and corrosion and, even so, it is susceptible to etching corrosion since it is in contact with different environments from mangrove regions to industrial environments. The present case evaluated the role of 5L X70 API steel in contact with different soil horizons representative of the Brazilian soil. This investigation correlated chemical species with solute ions in soil solution, secondary and primary phase minerals besides physical and chemical characteristics as pH, electric conductivity, total dissolved solids, among others, to the results of corrosion resistance and ways of corrosion. The evaluation was carried out using x-ray diffractometry, scanning electron microscopy, total reflection x-ray fluorescence, fuel injection flow besides texture and gravimetric analyses to soil characterization and mineralogy, identification of corrosion products, soil solution analyses, evaluation of tested materials and classification of ways and types of corrosion. This was an attempt to integrate the data to a better understanding of the process involving reagents and products. The results showed that different soil horizons such as different types of analyzed soils produce specific etching in metallic structures

  2. Hardness and microstructural characterization of API 5L X70 steel pipes welded by HF/ERW process; Caracterizacao microestrutural e de dureza em tubos de aco API 5L X70 soldados pelo processo HF/ERW

    Calcada, Mauricio Vieira; Voorwald, Herman Jacobus Cornelis; Nascimento, Marcelino Pereira do [UNESP, Guaratingueta, SP (Brazil). Faculdade de Engenharia

    2010-07-01

    The materials that stand in the manufacture of steel pipes are called API, that should have, high mechanical resistance, high corrosion resistance, high fatigue resistance, good weldability, and other properties. Thus, the purpose of this project was to evaluate the microstructure and hardness of welded joints by the HF/ERW process of API 5L X70 steel pipes. The microstructural analysis was performed using a surface finish with grit sizes from 220 to 25 {mu}m e polishing with diamond paste from 9 {mu}m to 0.05 {mu}m; the revelation was made with 3% Nital attack. The Vickers hardness was performed across the welded joint by 33 points to indentation. The results were: 80.5 {+-} 3.4% of ferrite and 19.5 {+-} 3.4% of perlite for microanalysis. As for hardness, the values were: 215.69 HV10 for weld line, 218.65 HV10 for ZTA and 218.95 HV10 for base metal. (author)

  3. Microbial Corrosion of API 5L X-70 Carbon Steel by ATCC 7757 and Consortium of Sulfate-Reducing Bacteria

    2014-01-01

    Various cases of accidents involving microbiology influenced corrosion (MIC) were reported by the oil and gas industry. Sulfate reducing bacteria (SRB) have always been linked to MIC mechanisms as one of the major causes of localized corrosion problems. In this study, SRB colonies were isolated from the soil in suspected areas near the natural gas transmission pipeline in Malaysia. The effects of ATCC 7757 and consortium of isolated SRB upon corrosion on API 5L X-70 carbon steel coupon were i...

  4. Study of API 5L X70 steel corrosion processes when in contact with some Brazilian soils

    Pipelines, fuel storage tanks and other metallic structures are in permanent contact and exposed to different types of soils, of horizons or layers, or of soil aggressiveness. This interaction may cause expressive damages to the environment and to the planned work. Contamination may occur due to leakage of stored products, splitting during transportation, accidents caused by pipelines without extensive maintenance. The result of these accidents could be, among others, some financial losses. In order to recognize the dynamic interactions between metallic surfaces and the environment it is crucial to have preventive actions and to develop better-applied materials. API steel 5L X70 has been used in structures of low and high pressure with high mechanical strength and corrosion and, even so, it is susceptible to etching corrosion since it is in contact with different environments from mangrove regions to industrial environments. The present case evaluated the role of 5L X70 API steel in contact with different soil horizons representative of the Brazilian soil. This investigation correlated chemical species with solute ions in soil solution, secondary and primary phase minerals besides physical and chemical characteristics as pH, electric conductivity, total dissolved solids, among others, to the results of corrosion resistance and ways of corrosion. The evaluation was carried out using x-ray diffractometry, scanning electron microscopy, total reflection x-ray fluorescence, fuel injection flow besides texture and gravimetric analyses to soil characterization and mineralogy, identification of corrosion products, soil solution analyses, evaluation of tested materials and classification of ways and types of corrosion. This was an attempt to integrate the data to a better understanding of the process involving reagents and products. The results showed that different soil horizons such as different types of analyzed soils produce specific etching in metallic structures

  5. Microbial Corrosion of API 5L X-70 Carbon Steel by ATCC 7757 and Consortium of Sulfate-Reducing Bacteria

    Arman Abdullah

    2014-01-01

    Full Text Available Various cases of accidents involving microbiology influenced corrosion (MIC were reported by the oil and gas industry. Sulfate reducing bacteria (SRB have always been linked to MIC mechanisms as one of the major causes of localized corrosion problems. In this study, SRB colonies were isolated from the soil in suspected areas near the natural gas transmission pipeline in Malaysia. The effects of ATCC 7757 and consortium of isolated SRB upon corrosion on API 5L X-70 carbon steel coupon were investigated using a weight loss method, an open circuit potential method (OCP, and a potentiodynamic polarization curves method in anaerobic conditions. Scanning electron microscopy (SEM and energy dispersive X-ray spectroscopy (EDS were then used to determine the corrosion morphology in verifying the SRB activity and corrosion products formation. Results from the study show that the corrosion rate (CR of weight loss method for the isolated SRB is recorded as 0.2017 mm/yr compared to 0.2530 mm/yr for ATCC 7757. The Tafel plot recorded the corrosion rate of 0.3290 mm/yr for Sg. Ular SRB and 0.2500 mm/yr for Desulfovibrio vulgaris. The results showed that the consortia of isolated SRB were of comparable effects and features with the single ATCC 7757 strain.

  6. Study of texture and microstructure evaluation of steel API 5L X70 under various thermomechanical cycles

    Masoumi, Mohammad, E-mail: Mohammad@alu.ufc.br; Herculano, Luis Flavio Gaspar; Ferreira Gomes de Abreu, Hamilton

    2015-07-15

    This work studies the influence of different thermomechanical paths on the microstructure and crystallographic texture across the thickness of API 5L X70 pipeline steel manufactured via hot rolling using X-ray diffraction (XRD), scanning electron microscope (SEM), and electron backscattered diffraction (EBSD). The starting materials were controlled hot-rolled at 1000 °C to 44% and 67% reductions and subsequently heat treated with such processes as annealing, water quenching and quench tempering at three different temperatures to evaluate the microstructure and crystallographic texture changes across the thickness. The banded ferrite-pearlite microstructure of the initial material was changed to acicular ferrite, quasi-polygonal ferrite, granular bainite, martensite and retained austenite via different heat treatments. Moreover, different thermomechanical paths induced crystallographic texture variations across the thickness, e.g., {112}//ND, {111}//ND (γ fibre), and {011}//ND fibres dominated on the surface plane in contact with the rolls, whereas {001}//ND and particularly the (001)[1 1 0] texture component developed in the centre plane on which shear deformation has a zero value in this region. In this study, a simple interpretation of texture evolution was analyzed by comparison with the orientation changes that occurred during different rolling schedules and post-treatment processes.

  7. Study of texture and microstructure evaluation of steel API 5L X70 under various thermomechanical cycles

    This work studies the influence of different thermomechanical paths on the microstructure and crystallographic texture across the thickness of API 5L X70 pipeline steel manufactured via hot rolling using X-ray diffraction (XRD), scanning electron microscope (SEM), and electron backscattered diffraction (EBSD). The starting materials were controlled hot-rolled at 1000 °C to 44% and 67% reductions and subsequently heat treated with such processes as annealing, water quenching and quench tempering at three different temperatures to evaluate the microstructure and crystallographic texture changes across the thickness. The banded ferrite-pearlite microstructure of the initial material was changed to acicular ferrite, quasi-polygonal ferrite, granular bainite, martensite and retained austenite via different heat treatments. Moreover, different thermomechanical paths induced crystallographic texture variations across the thickness, e.g., {112}//ND, {111}//ND (γ fibre), and {011}//ND fibres dominated on the surface plane in contact with the rolls, whereas {001}//ND and particularly the (001)[1 1 0] texture component developed in the centre plane on which shear deformation has a zero value in this region. In this study, a simple interpretation of texture evolution was analyzed by comparison with the orientation changes that occurred during different rolling schedules and post-treatment processes

  8. Development of high strength pipes grade API 5L X70 PSL2 offshore by the HFIW Process (High Frequency Induction Welding)

    Cordeiro, Wilson R.; Melo, Luis C.R.; Gomes, Igor O.; Boni, Luiz P.; Sanctis, Marco A.M. di [Apolo Tubulars, Lorena, SP (Brazil)

    2009-07-01

    High strength pipes can be manufactured with excellency in dimensional tolerances, rapidity and efficiency through HFIW process (High Frequency Induction Welding). API 5L 6 5/8 x 0,374 in pipes were made of thin, hot rolled and coiled plates with dimensional 9,300 x 1.040,0 x 140.000 mm. Mechanical tests, chemical and microstructural analysis were performed. For the microstructural analysis, ferrite and perlitic structure were detected. All the results obtained are according to API 5L, 44{sup th} edition, 2008 for the grade API 5L X70 PSL2 Offshore. (author)

  9. Obtaining and analysis of results of fatigue and corrosion-fatigue in steel API 5L X60; Obtencao e analise de resultados de fadiga e corrosao-fadiga em aco API 5L X60

    Araujo, Bruno Allison [Universidade Federal de Campina Grande (UFCG), PB (Brazil). Programa de Pos-Graduacao em Ciencia e Engenharia de Materiais; Silva, Antonio Almeida; Santos, Fabio Gualberto Chagas [Universidade Federal de Campina Grande (UFCG), PB (Brazil)

    2008-07-01

    The corrosion process allied to the fatigue, due to repetitive efforts of several natures, is the main responsible for the damages in pipeline and offshore structures that results in the appears of located faults, and by the way can results in leaks and financial and environmental loss. This phenomenon calls corrosion-fatigue, however, it is very complex, and mainly, in what it concerns the form as this it develops in the structure. The objective of this work is to present some results of experimental fatigue tests and corrosion-fatigue accomplished with specimen that the material originated a pipeline steel API 5L X60. The tests developed in a machine which could test until 12 specimens per time. For test of corrosion-fatigue was used a cell-of-corrosion especially projected, in this way simulated an aggressive environmental condition in a corrosion conditions. With the results of tests, was possible estimate the fatigue limits of the specimen when submitted to the repeated flexing, and compare it with evaluate corrosion-fatigue graphs, that as the literature comes moved down of the curve, in relation to the fatigue curve. (author)

  10. Envelhecimento por Deformação em Juntas Soldadas de Tubos de Aço API5L X65Q sem Costura

    Rodolfo Lisboa Batalha

    2015-09-01

    Full Text Available Resumo Neste trabalho, investigaram-se efeitos do fenômeno de envelhecimento por deformação em juntas obtidas por soldagem a arco elétrico com proteção gasosa (GMAW, de tubos sem costura de aço API5L X65Q. Corpos de prova (CPs obtidos a partir das juntas soldadas foram submetidos à uma deformação plástica a frio de 3% e posteriormente envelhecidas por 1h a 250°C, de forma a se induzir envelhecimento estático. Buscando avaliar o envelhecimento dinâmico, os CPs foram deformados até 3% e o carregamento foi mantido durante 1h a 250°C. Os CPs envelhecidos foram submetidos a ensaios de tração e amostras representativas foram analisadas ao microscópio óptico e microscópio eletrônico de varredura. Observou-se que o fenômeno modificou a fração volumétrica de constituintes secundários no metal de solda e na ZTA, com aumento na proporção de agregados ferrita-carbonetos. Com relação às propriedades mecânicas, constatou-se que o fenômeno reduziu a razão elástica das juntas soldadas devido a um aumento no limite de resistência, além de aumentar o alongamento total, não prejudicando, portanto, as propriedades mecânicas em tração das juntas soldadas. Ao se comparar o envelhecimento estático com o envelhecimento dinâmico, observou-se que o aumento na capacidade de deformação plástica das juntas soldadas foi maior após envelhecimento estático por deformação.

  11. Fatigue behaviour of X70 steel in crude oil

    Gajdoš, Lubomír; Šperl, Martin; Bystrianský, J.

    2015-01-01

    Roč. 49, č. 2 (2015), s. 243-246. ISSN 1580-2949 R&D Projects: GA ČR(CZ) GAP105/10/2052; GA TA ČR(CZ) TE02000162 Institutional support: RVO:68378297 Keywords : corrosion fatigue * S-N curve * X70 steel * crude oil * separated water Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 0.548, year: 2014 http://mit.imt.si/Revija/izvodi/mit152/gajdos.pdf

  12. X70管线钢焊缝弯曲不合格原因分析%Analysis on Weld Bending Disqualified Reason of X70 Pipeline Steel

    陈晓林

    2011-01-01

    检验管线钢管焊接接头塑性性能最直接、最有效的方法是弯曲试验.简要介绍了X70管线钢管的力学性能、主要化学成分、弯曲试验条件以及API SPEC 5L中对弯曲试验合格试样的判定标准.从焊缝的夹渣及气孔、脆性断裂、焊趾开裂和裂纹源等方面分析了弯曲试验不合格的现象及产生原因.最后分别给出了降低夹渣及气孔、脆性断裂、焊趾开裂等缺陷的具体措施.%The most direct and the most effective method to check welded joint plasticity of line pipe is bending test In this article,it briefly introduced the mechanical performance,main chemical compositions,bending test condition and judgment standard to qualified specimen in API SPEC 5L,and analyzed disqualified phenomena and cause for bending test from weld inclusions,gas pocket,brittle fracture,welding toe cracking,crack source and etc. Finally,it gave specific measures to reduce inclusions,gas pocket,brittle fracture,welding toe cracking and etc.

  13. Effect of Environmental Factors on Electrochemical Behavior of X70 Pipeline Steel in Simulated Soil Solution

    ZHANG Liang; LI Xiao-gang; DU Cui-wei

    2009-01-01

    Potentiodynamic polarization measurement was used to investigate the effects of temperature, dissolved ox-ygen concentration and pH on the electrochemical behavior of X70 pipeline steel in simulated solution according to the orthogonal testing method. The results showed that temperature, dissolved oxygen concentration and pH had great influence on corrosion current density (icorr)of X70 steel. Corrosion current density of X70 steel was most influenced by dissolved oxygen concentration in simulated solution. The corrosion degree of X70 steel was the least under the environment of low temperature, deficient oxygen and weak acid.

  14. Welding technique and quality of large diameter X70 line pipe for gas transmission of China

    2005-01-01

    X70 grade large diameter line pipe with helical and longitudinal seam SAW was developed and used in West-East Pipeline Project of Petrochina. The operation pressure of the pipeline was designed as 10 MPa, with diameter of 1016 mm OD. This project represents the first high-pressure, large diameter and high strength grade gas pipeline in China. All the factors affecting the safety of the pipeline shall be considered. The welds quality of line pipe is very important for safety of the pipeline. Acicular ferrite type X70 grade pipeline steel was adopted for the base material. The welds performances of X70 line pipes with 1016mm OD and 14.6-21.0 mm WT has reached a very high level, especially of low temperature Charpy V impact toughness of welds metal. Welding technique and quality status of X70 line pipe of China are investigated in this paper.

  15. Hydrogen embrittlement in subsea pipelines made from X70: Effect of plastic deformation on hydrogen diffusion

    Hauge, Anders Senumstad

    2011-01-01

    As a part of the DEEPIT project at SINTEF, hydrogen permeation tests have been carried out on API X70 pipeline steel. The effect of plastic deformationon hydrogen diffusion properties has been evaluated, using a worldwide unique permeation apparatus at NTNU. The apparatus is a purposebuild advanced version the standard hydrogen cell presented by Devanathan and Stachurski [1] in 1962.API X70 steel has been tested both in base metal (BM) and simulated heat affected zone (HAZ) conditions. The he...

  16. Tension fracture behaviors of welded joints in X70 steel pipeline

    2011-01-01

    The surface of welded joints in X70 steel pipeline was processed by laser shock wave, its mechanical behaviors of tension fracture were analyzed with tension test,and the fracture morphologies and the distributions of chemical element were observed with scanning electron microscope and energy dispersive spectrum,respectively.The experimental results show that the phenomenon of grain refinement occurs in the surface of welded joints in X70 steel pipeline after the laser shock processing,and compressive re...

  17. Effect of the welding process on the microstructure and microhardness of API 5L X80 steel welded joint used for oil transportation pipeline; Efeito do processo de soldagem sobre a microestrutura e a microdureza de juntas soldadas de aco API 5L X80 usado em tubulacoes para transporte de petroleo

    Alves, R.T.P.; Albuquerque, S.F. [Universidade Federal de Campina Grande (UFCG), PB (Brazil); Maciel, T.M.; Almeida, D.M.; Santos, M.A.

    2008-07-01

    This study had as objective to evaluate the microstructure and microhardness of API 5L X80 steel welded joints, used for pipelines to transport oil and gas, using the Shield Metal Arc Welding process with pre- heating temperature of 200 deg C and 400 deg C and the AWS E8010G electrode as filler metal. For this, besides the microhardness of the welded joint, the weld metals percentiles of micro-constituents and of columnar and regenerated grains and the medium size and extension of the heat affected zone were evaluated. The percentage of acicular ferrite in weld metal ranged from 13% to 33% which generated values of microhardness from 114 HV to 309 HV. (author)

  18. Anodic Dissolution of API X70 Pipeline Steel in Arabian Gulf Seawater after Different Exposure Intervals

    El-Sayed M. Sherif

    2014-01-01

    Full Text Available The anodic dissolution of API X70 pipeline steel in Arabian Gulf seawater (AGSW was investigated using open-circuit potential (OCP, electrochemical impedance spectroscopy (EIS, cyclic potentiodynamic polarization (CPP, and current-time measurements. The electrochemical experiments revealed that the X70 pipeline steel suffers both general and pitting corrosion in the AGSW solution. It was found that the general corrosion decreases as a result of decreasing the corrosion current density (jcorr, corrosion rate (Rcorr and absolute currents as well as the increase of polarization resistance of X70 with increasing the exposure time. On the other hand, the pitting corrosion was found to increase with increasing the immersion time. This was confirmed by the increase of current with time and by the SEM images that were obtained on the steel surface after 20 h immersion before applying an amount of 0–.35 V versus Ag/AgCl for 1 h.

  19. Development of X70MS Grade Acid-resistance SAWL Pipe%抗酸性X70MS直缝埋弧焊管的研制

    黄晓辉; 毕宗岳; 牛辉; 张世涛; 牛爱军; 吴佩军; 陈长青

    2014-01-01

    采用低C、低Mn、合金化设计和超洁净化冶炼制造的X70MS抗酸性钢板,通过控制焊接接头硬度、焊接热输入以及钢管残余应力等,开发制造出了X70MS抗酸性直缝埋弧焊管,并对焊管管体和焊缝组织性能进行了研究。结果表明,管体和焊缝的硬度均小于250HV10,0℃下母材冲击功大于410 J,焊接接头冲击功大于168 J;按照NACE-0284标准进行HIC测试,管母和焊接接头裂纹敏感率(CSR)、裂纹长度率(CLR)及裂纹厚度率(CTR)均为0;按照NACE-0177标准进行SSCC测试,采用A溶液,在72% ReL及90% ReL载荷下,管母和焊接接头均未出现断裂,管材表现出良好的力学性能和耐酸性。%The X70MS grade acid-resistance steel plate was produced by using the technology of low carbon, low manganese, microalloying design and clean smelting. By controlling the hardness of welded joints, welding heat input and the residual stress of steel pipe, the X70MS grade acid-resistance SAWL pipe was developed. Test results showed that the hardness of pipe body and weld both are less than 250 HV10. Under 0℃, the impact energy of base metal is greater than 410 J, and the impact energy of welded joint is greater than 168 J. The HIC tests were conducted in accordance with the NACE-0284 standard, the cracking sensitivity (CSR) of base metal and welded joints, the crack length ratio (CLR), and the crack thickness ratio (CTR) are all zero;The SSCC tests were conducted in accordance with NACE-0177 standard by using A solution under 72% ReL and 90% ReL loading, the fracture did not appear in base metal and welded joints, the pipes showed good mechanical properties and acid resistance.

  20. Research & Development of Grade X70 LSAW Steel Pipes for West-East Gas Pipeline

    WangXiaoxiang; SunQi

    2004-01-01

    In this article the research and development of X70 large diameter longitudinal seam submerged arc welded (LSAW) steel pipes for West-East Gas Transportation Pipeline project (WEGTP) in China are introduced, including the key technique, fabrication of pipe production line, mass production and the latest progress of LSAW steel pipe technique.

  1. X70管线钢焊接接头断裂韧性分析%Fracture Toughness of X70 Pipeline Steel Welded Joints

    祝少华; 杨军; 张万鹏; 张超

    2013-01-01

    The crack tip opening displacement (CTOD) test is usually used to evaluate material toughness. In this article, it detailedly introduced CTOD test procedure, operation steps and fitting method of calculation. In addition, it adopted CTOD test to conduct fracture toughness study for the weld in welded joints, HAZ and base metal of X70 Pipeline steel. The result showed that under the same temperature, the CTOD characteristic valuesδ0.05,δ0.2 andδ0.2BL of base metal is the highest, the HAZ is the second, and the weld is the lowest, that is to say the fracture toughness of base metal is the best, the fracture toughness of HAZ is better than that of weld, and the weld is the worst.%裂纹尖端张开位移(CTOD)试验常被用来进行材料的韧性评价。详细介绍了CTOD试验的过程、操作步骤及计算拟合方法。并采用裂纹尖端张开位移试验对X70管线钢焊接接头处焊缝、热影响区(HAZ)和母材进行了断裂韧性的测试研究。结果表明,在同一温度下, CTOD特征值δ0.05,δ0.2和δ0.2BL均呈现母材最大、热影响区次之、焊缝最小,即母材断裂韧性最优、热影响区次之、焊缝最差。

  2. A new method for preparing bionic multi scale superhydrophobic functional surface on X70 pipeline steel

    Yu, Sirong; Wang, Xiaolong; Wang, Wei; Yao, Qiang; Xu, Jun; Xiong, Wei

    2013-04-01

    The hydrophobic property of a rough surface with a low free energy coating was theoretically analyzed in this paper. In order to obtain a superhydrophobic surface, a rough surface morphology must be formed in addition to the low free energy coating on the surface. Through the shot blasting, chemical etching with concentrated hydrochloric acid, and low free energy modification with myristic acid ethanol solution, the superhydrophobic surface was obtained on X70 pipeline steel. The better process parameters for preparing superhydrophobic surface on X70 pipeline steel were obtained. The diameter of the stainless steel shot used in the shot blasting was 0.8-1.0 mm. The concentration of hydrochloric acid was 6 mol/L. The chemical etching time was 320 min. The concentration of myristic acid ethanol solution was 0.1 mol/L. The soaking time in myristic acid ethanol solution was 72 h. After X70 pipeline steel surface was treated using the process parameters mentioned above, the biggest contact angle between the specimen surface and distilled water was 153.5°, and the sliding angle was less than 5°.

  3. Fatigue crack growth rate of API X70 steel pipelines under spectrum loading

    Pipelines offer the most efficient way to transport bulk quantities of gas and oil, either from points of production to storage locations or from storage locations to distributed points of end use. As one of the main materials of west–east gas transmission pipes, X70 pipelines usually serve under variable amplitude loading (VAL). Base on the importance of in-service API X70 pipelines, it is important for the safe operation of this system to know its behaviour under VAL. This paper focuses on the ability of using the NASGRO model to predict the fatigue crack growth (FCG), based on investigation with the modified Wheeler model and experimental data. The results show that the NASGRO model give a fatigue life near by to that published in literatures and also showed the FCG rate response of X70 pipeline steels when exposed to VAL with different overload values. Extra modification to the NASGRO model may lead to better representing of FCG rate. Highlights: ► The assessment of fatigue crack propagation under different load histories are proposed and presented in this paper. ► Due to lack of knowledge in the related area, as yet no universal model exists. ► The output was based on both simulation and experiments. The simulation part was carried out based on the NASGRO model. ► This work focus on fatigue crack growth (FCG) and fatigue life based on the comparison with the previous work.

  4. Effects of Cl- and SO2-4 Ions on Corrosion Behavior of X70 Steel

    Junwei WU; Xiaogang LI; Cuiwei DU; Song WANG; Yiquan SONG

    2005-01-01

    Corrosion behaviors of X70 steel were studied by means of electrochemical experiments and morphology observation.First, through potentiodynamic polarization in solution of various Cl- ions concentration, it was found that Epit began to appear in solution of Cl- concentration above 0.1 mol/L, and there was a critical point of Cl- concentration between 0.05 mol/L and 0.1 mol/L, below which the extent of pitting and general corrosion were trivial, while in solution of Cl- concentration above 0.1 mol/L, general and pitting corrosion became greater as the increasing of Cl- concentration. All of them were confirmed by the SEM observations after anodic polarization. Second, via the potentiodynamic polarization curves of X70 steel in 0.5 mol/L Cl- solution with 0, 0.05, 0.5 and 1 mol/L SO42-ions, it was found SO42- ions were able to inhibit corrosion aroused from Cl- ions, accordingly a model was set up to describe the process. In addition, to further explore the inhibited effect of SO42- ions, EIS was used in solutions of different Cl- and SO42- concentrations, the results revealed that the e(ectrochemical resistance has a relation with the [SO42-]/[Cl-], that was, the bigger the value of [SO42-]/[Cl-], the greater the electrochemical resistance.

  5. Construction and assembly of pipelines using API 5L grade X80 tubes - considerations to be observed with high-strength steels; Construcao e montagem de dutos terrestres utilizando tubos API 5L Gr. X80

    Oliveira, Ailton C. de; Rabello, Jose Mauricio B. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

    2005-07-01

    The use of line pipes API 5L Grade X80, at the point of view of designer allows: reduction of wall thickness and pipe weight or increase of design pressure. In the pipeline construction point of view, the use of line pipes API 5L Grade X80 provide some advantages, however some difficulties must be expected in several stages of the construction and assembly. The implications in cost, productivity, inspection and integrity, with the application of these high resistance steels, complying with PETROBRAS Standard N - 464 Construcao, Montagem e Condicionamento de Dutos Terrestres (Rev. H - 2004 Dec) and the experience consolidated in pipelines construction abroad were presented. At the design stage, a comparison between pipelines designed using API 5L-X70 and API 5L-X80 was carried out approaching the aspects of variation of thickness, pressure design and design factor. An evaluation of the expected gains when choosing API 5L Grade X80 steels were done, regarding reduction of costs and pipe weight. Regarding API 5L-X80 pipe fabrication, the obtained results were reported, proving that this aspect was already overcome, showing the viability of its production in Brazil. Difficulties were detected regarding construction and assembly stage and showing the need of revision of PETROBRAS standard N-464. (author)

  6. Oblique Y-groove cracking test of the welding cold cracking susceptibility of domestic X-70 pipeline steel

    陈丽萍; 杜则裕; 李云涛; 李九生

    2002-01-01

    "Gas Transmitting From West to East Project" is significant. It should ensure the welding quality and safety of pipeline. The task is very arduous to guarantee the quality of the project in the condition of long line, complex weather and geology features. In this paper, the welding cold cracking susceptibility of domestic X-70 pipeline steel adopted by the project, which is one of the most interesting questions of welding quality about petrol pipeline, was studied by means of oblique Y-groove cracking test. The crack ratio of surface and section was tested under the conditions of different welding materials and preheat temperature .The X-70 pipeline steel has good crack resistance. The research has important value for the construction of large-scale pipeline engineering and the application of domestic X-70 pipeline steel.

  7. Correlation of microstructure and fracture properties of API X70 pipeline steels

    Hwang, Byoungchul; Kim, Young Min; Lee, Sunghak; Kim, Nack J.; Ahn, Seong Soo

    2005-03-01

    Effects of microstructure on fracture toughness and transition temperature of high-toughness X70 pipeline steels were investigated in this study. Three types of steels were fabricated by varying alloying elements such as C, Cu, and Mo, and their microstructures were varied by rolling conditions such as finish rolling temperature and finish cooling temperature. Charpy V-notch (CVN) impact tests and pressed notch drop-weight tear tests (DWTT) were conducted on the rolled steel specimens. The charpy impact test results indicated that the specimens rolled in the single-phase region of the steel containing a reduced amount of C and Mo had the highest upper shelf energy (USE) and the lowest energy transition temperature (ETT) because of the appropriate formation of acicular, quasipolygonal, or polygonal ferrite and the decreased fraction of martensite-austenite constituents. Most of the specimens rolled in the single-phase region also showed excellent DWTT properties as the percent shear area (pct SA) well exceeded 85 pct, irrespective of finish cooling temperatures, while their USE was higher than that of the specimens rolled in the two-phase region. Thus, overall fracture properties of the specimens rolled in the single-phase region were better than those of the specimens rolled in the two-phase region, considering both USE and pct SA.

  8. Texture Study Across Thickness of API X70 Steel After Hot Deformation and Different Posttreatments

    Masoumi, M.; Herculano, L. F. G.; Almeida, A. A.; Béreš, M.; de Abreu, H. F. G.

    2016-01-01

    In the present study, the texture heterogeneity across the thickness of API X70 steel subjected to hot deformation and different posttreatments was investigated. X-ray diffraction and electron backscattered diffraction were used to analyze crystallographic orientation and grain boundary distributions at the center and surface layers of specimens. The initial material was rolled at 1000°C to 67% reduction; then one deformed sample was cooled in air, and the others were quenched in water and finally tempered at 350°C and 700°C for 1 h. The shear strain generated by friction between rolls and strip induces heterogeneity across thickness. The results showed that in the center layer, the (001)[ bar{1}bar{1}0 ] texture dominated in all specimens, whereas the {110}//ND component was developed at the surface layer. Furthermore, a local misorientation histogram showed that the surface layer was subjected to a higher degree of deformation in comparison with the center layer due to additional shear deformation.

  9. Slow strain rate corrosion and fracture characteristics of X-52 and X-70 pipeline steels

    The susceptibility to stress corrosion cracking (SCC) in a NACE solution saturated with H2S, of the X-52 and X-70 steels was studied using slow strain rate tests (SSRT) and electrochemical evaluations. SCC tests were performed in samples which include the longitudinal weld bead of the pipeline steels and were carried out in the NACE solution at both room temperature and 50 deg. C. After failure, the fracture surfaces were observed in a scanning electron microscope (SEM) and the chemical analysis were obtained using X-rays energy dispersive (EDXs) techniques. The specimens tested in air, exhibited a ductile type of failure, and whereas, those tested in the corrosive solution showed a brittle fracture. Specimens tested in the NACE solution saturated with H2S presented high susceptibility to SCC. Corrosion was found to be an important factor in the initiation of some cracks. In addition, the effect of the temperature on the corrosion attack was explored. The susceptibility to SCC was manifested as a decrease in the mechanical properties. Potentiodynamic polarization curves and hydrogen permeation measurements were made. The diffusion of atomic hydrogen was related to this fracture forms. The hydrogen permeation flux increased with the increasing of temperature

  10. Research and Development of X70 with an Acicular Ferrite Microstructure for West-East Pipeline Project

    ZhengLei; GaoShan

    2004-01-01

    It is introduced in this paper that a high strength and high toughness X70 pipeline steel with an ultra-low acicular ferrite microstructure has been researched and developed at Baosteel according to the requirements of the West-East Gas Pipeline(WEGTP) project. The developed steel has higher strength, higher toughness, lower ductile-brittle transition temperature and higher dynamic tear-resistance than the conventional X70 with ferrite and pearlite microstructure. The excellent properties of the steel are benefited from ultralow carbon acicular ferrite consisting of interaction of very fine precipitated particles and high-density dislocation. And the steel has been applied on the WEGTP in China.

  11. The Effect of Chemical Composition on Microstructure and Properties of Intercritically Reheated Coarse-Grained Heat-Affected Zone in X70 Steels

    Zhu, Zhixiong; Kuzmikova, Lenka; Li, Huijun; Barbaro, Frank

    2013-12-01

    The current study investigates the effect of different levels of Ti, N, and Ti/N ratios on microstructure and properties in the intercritically reheated coarse-grained heat-affected zone (ICCGHAZ) of two-pass submerged arc welds in API 5L grade X70 pipe. Gleeble simulation was employed to reproduce the ICCGHAZ of actual welds. Hardness and Charpy V-notch (CVN) tests were performed on the simulated samples. The microstructure of simulated ICCGHAZ was characterized by optical microscopy and scanning electron microscopy (SEM). LePera color etching technique was employed to identify and quantify the martensitic-austenitic (M-A) constituent. Results show that the simulated ICCGHAZ exhibited extremely low toughness, but in the studied range of Ti and N, there was no correlation with Ti/N ratio. The beneficial effect of near-stoichiometric Ti/N ratio observed in coarse-grained heat-affected zone (CGHAZ) did not translate to ICCGHAZ. This was because of the negative effect of the blocky M-A constituent formed on prior austenite grain boundaries.

  12. Effect of inter-critically reheating temperature on microstructure and properties of simulated inter-critically reheated coarse grained heat affected zone in X70 steel

    Zhu, Zhixiong, E-mail: zhixiongzhu@gmail.com [School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, Wollongong, NSW 2522 (Australia); Kuzmikova, Lenka; Li, Huijun [School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, Wollongong, NSW 2522 (Australia); Barbaro, Frank [School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, Wollongong, NSW 2522 (Australia); CBMM Technology Suisse, 14, Rue du Rhone, Geneva 1204 (Switzerland)

    2014-05-01

    This study investigated the influence of the inter-critical reheating temperature on the microstructure and mechanical properties of a coarse grained heat affected zone (CGHAZ) in an API 5L grade X70 pipeline steel seam weld. A Gleeble 3500 thermo-mechanical simulator was employed to duplicate particular weld thermal cycles in order to accurately assess specific regions of the weld HAZ. Detailed microstructural analysis, including investigation of the martensite–austenite (M–A) constituent, was performed using optical microscope (OM), scanning electron microscope (SEM) and selective etching techniques. It is shown that the fracture toughness of the CGHAZ is significantly reduced following exposure to a subsequent inter-critical thermal cycle. Fracture toughness gradually improves as the inter-critical temperature is increased, but does not return to the value of the original CGHAZ due to the presence of isolated large M–A particles and coarse microstructure. Significance of M–A particles to the HAZ fracture toughness is first related to the location of particles along prior austenite grain boundaries, followed by the size of individual M–A particles.

  13. Effect of inter-critically reheating temperature on microstructure and properties of simulated inter-critically reheated coarse grained heat affected zone in X70 steel

    This study investigated the influence of the inter-critical reheating temperature on the microstructure and mechanical properties of a coarse grained heat affected zone (CGHAZ) in an API 5L grade X70 pipeline steel seam weld. A Gleeble 3500 thermo-mechanical simulator was employed to duplicate particular weld thermal cycles in order to accurately assess specific regions of the weld HAZ. Detailed microstructural analysis, including investigation of the martensite–austenite (M–A) constituent, was performed using optical microscope (OM), scanning electron microscope (SEM) and selective etching techniques. It is shown that the fracture toughness of the CGHAZ is significantly reduced following exposure to a subsequent inter-critical thermal cycle. Fracture toughness gradually improves as the inter-critical temperature is increased, but does not return to the value of the original CGHAZ due to the presence of isolated large M–A particles and coarse microstructure. Significance of M–A particles to the HAZ fracture toughness is first related to the location of particles along prior austenite grain boundaries, followed by the size of individual M–A particles

  14. Study of sulphate-reducing bacteria corrosion in the weld joint for API X-70 steel

    Flores, J. E.

    2012-10-01

    Full Text Available The corrosion behavior originated by sulfate-reducing bacteria (SRB was studied in two regions of welded API X-70 steel pipeline. The studies were focused on base material (BM and heat affected zone (HAZ, from the internal region of the pipe. SRB were extracted from oil and grown in a Postgate medium. Corrosion was evaluated at 60 °C for times between 5 and 64 days. Potentiodynamic polarization curves, obtained by electrochemical techniques, indicated surface activation at short times. Structural and morphological characterizations were carried out by scanning electron microscopy (SEM and optical microscopy (OM. H2S concentration and pH were also measured. Results showed an important increase in the corrosion damage up to 20 days, influenced by the SRB activity, which lead to a maximum of H2S (pH minimum. It was found a localized corrosion attack in the HAZ in a higher quantity compared to BM; and the formation of a thin film on the steel surface, originated by corrosion products and bacterial activity.

    El comportamiento ante la corrosión, originada por bacterias sulfato-reductoras (SRB, fue estudiado en dos regiones de un tubo de acero soldado API X-70. Los estudios se enfocaron en el material base (BM y la zona afectada térmicamente (HAZ, en la parte interna del tubo. Las SRB fueron extraídas del petróleo y cultivadas en un medio Postgate. El comportamiento a la corrosión fue evaluado a una temperatura de 60 °C, por periodos comprendidos entre 5 y 64 días. El análisis de las curvas de polarización potenciodinámicas, obtenidas por técnicas electroquímicas, indicó la activación de la superficie para tiempos cortos. La superficie fue caracterizada estructural y morfológicamente mediante microscopia electrónica de barrido (SEM, así como mediante microscopía óptica (OM. La concentración de H2S y el pH también fueron medidos. Los resultados mostraron un aumento importante de la corrosi

  15. Hydrogen embrittlement susceptibility of a weld simulated X70 heat affected zone under H2 pressure

    The present paper deals with hydrogen embrittlement (HE) susceptibility of a weld thermal simulated heat affected zone of X70 structural steel in high pressure hydrogen gas at 20 °C. Fracture mechanics Single Edge Notched Tension tests at various hydrogen pressures (0.1, 0.6, 10 and 40 MPa H2) have been carried out. The HE susceptibility was quantified through the measurement of the fracture toughness KQ and J (the effect of hydrogen pressure was addressed through linear load increase conditions till failure was obtained). The results show that hydrogen causes a strong decrease in the fracture toughness with increasing hydrogen pressure. The critical hydrogen pressure for the onset of HE was observed to fall between 0.1 MPa and 0.6 MPa. These results were supported by Scanning Electron Microscope (SEM) investigations of the fracture surfaces which showed a clear shift in the fracture mode at 0.6 MPa H2. Moreover, constant load tests were carried out in order to investigate the influence of hydrogen exposure time. The results imply that fracture always occurs within 8 h and that longer time to failure is related to stronger toughness reduction. This effect is more pronounced for test at 40 MPa than at 0.6 MPa hydrogen pressure levels. 3D Finite Element calculations of hydrogen diffusion have been performed and the results are discussed in relation to the experiments, in order to attempt to identify the hydrogen populations (diffusible or trapped) which act predominantly on the embrittlement of the material

  16. Research on anti-corrosion property of rare earth inhibitor for X70 steel

    ZHU Yanhua; ZHUANG Jia; YU Yongsheng; ZENG Xianguang

    2013-01-01

    Three kinds of rare earth nitrates were adopted to sodium molybdate to get three kinds of LnN-M compounded inhibitors (La(NO3)3+Na2MoO4(LaN-M),Ce(NO3)3+Na2MoO4(CeN-M),Pr(NO3)3+Na2MoO4(PrN-M)).The combination of weight-loss method and the electrochemical test,was used to evaluate and analyze the corrosion inhibition efficiency of these LnN-M inhibitors to make the research on their corrosion inhibition performance,and the sequential order of their performance was found as follows:CeN-M> LaN-M>PrN-M,among which,the inhibition efficiency of CeN-M for the X70 steel could reach 98.21%.The synergism parameters were calculated by weight-loss method,these computational data indicated that the synergistic effect between rare earth nitrates and sodium molybdate was obvious and significant.Surface morphology,chemical composition and phase components of the precipitation films were tested for discussing the mechanism of LnN-M inhibitors.The outer electronic configuration of the lanthanide was found to have an important influence on the inhibition efficiency.The CeN-M inhibitor was discovered to have the best inhibition effect with the amorphous cerium oxides.The results of this research revealed that the precipitation films formed on the surface of the steel samples had a crucial influence on the inhibition efficiencies after adding LnN-M inhibitors.

  17. Research on the Non-metallic Inclusion in X70 Pipeline Cast Slab%X70管线钢铸坯中非金属夹杂物的研究

    吴雨晨; 李俊国; 闫小林; 李守章; 曾亚南

    2009-01-01

    利用大样电解、金相观测、扫描电镜(SEM)和电子探针(EPMA)等手段,对X70管线钢铸坯中夹杂物的数量、粒径、形貌及组分进行了研究.结果表明:X70管线钢铸坯中夹杂物数量较多,粒径较大,且多为复合夹杂.针对大型夹杂物中硫化物、氧化物、硅铝酸盐和钙铝酸盐复合夹杂的特点,分析了铸坯中夹杂物的主要来源.%Utilizing the methods of sample-electrolysing, metallographic observation, SEM and EPMA, the quantity, dimension, morphologies and composition of non-metallic inclusions in X70 pipeline steel cast slab were investigated. It was suggested that there were larger amount of inclusions with larger diam-eter in the cast slab. Most of these inclusions were complex, such as sulfide, oxide, silicon aluminates and calcium aluminates inclusions. According to the characteristics of inclusions in the east slab, the ma-jor sources of different inclusions were analyzed and explored.

  18. DECREASING PITTING SUSCEPTIBILITY OF PASSIVE FILMS ON X70 PIPELINE STEEL IN NaCl SOLUTIONS BY ILLUMINATION

    W.C. Zhu; W.H. Leng; J.Q. Zhang; C.N. Cao

    2006-01-01

    The influence of UV illumination on passivity and pitting susceptibility on X70 pipeline steel in a borate buffer (pH=8.4) solution containing NaCl is described. It is observed that illumination of the sample leads to a decrease in its pitting susceptibility as indicated by pitting potential and incubation time measurements in chloride containing electrolytes. This effect is strongly dependent on the applied potential during passivation. The electronic properties of the passive films on X70steel were studied by Mott-Schottky analysis and photocurrent transient measurements. The results indicated that illumination during passivation led to modifications in the electronic properties of the passive films, mainly to a decrease of the bulk doping and an increase in the surface state density. The cause for the decrease in the pitting susceptibility is preliminary explained in terms of such modifications of the passive film.

  19. 几种焊接缺陷对X70管道环缝接头应力集中的影响%Influences on Stress Concentration of X70 Pipeline Circumferential Weld Joints of Several Welding Defects

    李根; 张腾

    2014-01-01

    利用大型有限元软件ANSYS对在工作压力下带有咬边、凹坑、焊缝余高、错边等焊接缺陷的X70环缝管道进行了应力分析。分析结果显示,在咬边、凹坑、焊缝余高、错边焊接缺陷中,焊缝余高对受内压管道环焊缝的应力集中的影响最低,错边其次,咬边较为严重,凹坑最为严重;焊缝余高不影响X70管道接头静载强度,超过2 mm的错边量对环缝接头应力集中影响明显,咬边缺陷对X70管道环缝接头应力集中的影响大于错边,缺陷凹坑缺陷对环缝接头应力集中的影响随其三维尺寸增大而增大。%In this paper, the finite element analysis software ANSYS was used to carry out stress analysis on X70 pipeline under working pressure with welding defects, such as undercut, pit, weld reinforcement and misalignment. The results indicated that in the above defects, the influence on the weld reinforcement of stress concentration is the lowest, misalignment is the second, undercut is a bit severe, and the influence on pit is the most severe. The weld reinforcement does not affect the static load strength of X70 pipeline circumferential weld joints, and the influence of misalignment more than 2 mm on stress concentration is obvious. The influence of undercut on stress concentration is more than that of misalignment, and the influence of pit increases with three-dimensional size increasing.

  20. Micro-electrochemical characterization of corrosion of welded X70 pipeline steel in near-neutral pH solution

    Zhang, G.A. [Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive NW, Calgary, Alta., T2N 1N4 (Canada); Cheng, Y.F. [Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive NW, Calgary, Alta., T2N 1N4 (Canada)], E-mail: fcheng@ucalgary.ca

    2009-08-15

    The local corrosion behavior of welded X70 pipeline steel in near-neutral pH solution was studied by micro-electrochemical measurements, including scanning vibrating electrode and local electrochemical impedance spectroscopy. The microstructure of the welded steel was observed by optical microscopy and scanning electron microscopy. It is demonstrated that the microstructure of weld metal consists of acicular ferrite and grain boundary ferrite, while that of heat-affected zone is a mixture of acicular ferrite, bainitic ferrite and a few martensite/austenite microconstituents. The microstructure of base steel is typically ferrite and pearlite. Electrochemical corrosion mechanism of welded X70 steel does not experience change upon hydrogen-charging, or stressing, or both. Hydrogen-charging is capable of enhancing the local anodic dissolution of the steel. The resistance of corrosion product layer decreases with hydrogen-charging, and heat-affected zone has the largest dissolution current upon hydrogen-charging. The increase of applied stress enhanced the anodic dissolution of welded X70 steel, especially the heat-affected zone, in near-neutral pH solution. Maximum current is observed in heat-affected zone, and increases with the increase of applied stresses. The total synergistic effect of hydrogen-charging (10 mA/cm{sup 2}) and applied stress (550 MPa) on anodic dissolution of welded X70 steel in near-neutral pH solution is determined to be within the range of 5.7 and 6.5, with a maximum value encountering in heat-affected zone.

  1. Micro-electrochemical characterization of corrosion of welded X70 pipeline steel in near-neutral pH solution

    The local corrosion behavior of welded X70 pipeline steel in near-neutral pH solution was studied by micro-electrochemical measurements, including scanning vibrating electrode and local electrochemical impedance spectroscopy. The microstructure of the welded steel was observed by optical microscopy and scanning electron microscopy. It is demonstrated that the microstructure of weld metal consists of acicular ferrite and grain boundary ferrite, while that of heat-affected zone is a mixture of acicular ferrite, bainitic ferrite and a few martensite/austenite microconstituents. The microstructure of base steel is typically ferrite and pearlite. Electrochemical corrosion mechanism of welded X70 steel does not experience change upon hydrogen-charging, or stressing, or both. Hydrogen-charging is capable of enhancing the local anodic dissolution of the steel. The resistance of corrosion product layer decreases with hydrogen-charging, and heat-affected zone has the largest dissolution current upon hydrogen-charging. The increase of applied stress enhanced the anodic dissolution of welded X70 steel, especially the heat-affected zone, in near-neutral pH solution. Maximum current is observed in heat-affected zone, and increases with the increase of applied stresses. The total synergistic effect of hydrogen-charging (10 mA/cm2) and applied stress (550 MPa) on anodic dissolution of welded X70 steel in near-neutral pH solution is determined to be within the range of 5.7 and 6.5, with a maximum value encountering in heat-affected zone.

  2. X70焊管焊接接头热影响区冲击试样缺口位置的探讨%Discussion on Impact Specimen Notch Position of X70 Welded Pipe Heat Affected Zone(HAZ)

    王丽丽; 刘通; 王自信; 顾志乾

    2015-01-01

    In this article, it studied the distribution situation of metallographic structure, impact energy and shearing area of X70 SAWH pipe welded joint HAZ specimen in different Notch position, by adopting metallographic test and Charpy impact test. The results indicated that the values of impact energy value and shearing area are related with Notch position proportion in coarse grained region, fine grained region, part of the phase change zone and inside weld. The lower the proportion of inside weld is, the greater the impact energy and shearing area. After comprehensive analysis of test results and related standards, the determination method of X70 SAWH pipe welded joint HAZ specimen Notch position was obtained; the Notch axis of HAZ impact specimen should be in the junction of specimen upper surface and outside weld fusion line, and the distance from Impact test specimen edges to the outside weld edge of 1~2 mm is applicable.%通过金相试验、夏比冲击试验研究了X70螺旋埋弧焊管焊接接头热影响区试样不同缺口位置的金相组织、冲击功及剪切面积的分布情况。试验结果显示,冲击功和剪切面积的大小与缺口位置在粗晶区、细晶区、部分相变区和内焊缝所占的比例相关,内焊缝所占比例越低,冲击功和剪切面积越大。综合分析试验结果和相关标准,得出了X70焊管焊接接头热影响区试样缺口位置的确定方法,即热影响区冲击试样的缺口轴线应在试样上表面与外焊缝熔合线交界处,冲击试样边缘距外焊缝边缘1~2 mm为宜。

  3. Effect of Cyclic Loading on Cracking Behaviour of X-70 Pipeline Steel in Near-Neutral pH Solutions

    Hao GUO; Guangfu LI; Xun CAI; Ruipeng YANG; Wu YANG

    2005-01-01

    The cracking behaviour of X-70 pipeline steel in near-neutral pH solutions was studied under different modes of cyclic loading. The crack propagation process of X-70 pipeline steel under low frequency cyclic loading condition was controlled mainly by stress corrosion cracking (SCC) mechanism. Under mixed-mode cyclic loading, both higher tensile stress and shear stress made cracks easier to propagate. Applied cathodic potentials and high content of carbon dioxide in solutions also promoted the propagation of cracks. The propagation directions of cracks were different under different cyclic loading conditions. Under mode I (pure tensile stress) cyclic loading condition, cracks were straight and perpendicular to the tensile stress axis, while under mixed-mode Ⅰ/Ⅲ (tensile/shear stress) cyclic loading,cracks were sinuous and did not propagate in the direction perpendicular to the main tensile stress axis. Under the mixed-mode cyclic loading, cracks were much easier to propagate, suggesting that shear stress intensified the role of tensile stress. In addition, shear stress promoted the interaction between cracks, resulting in easier coalescence of cracks.

  4. Effect of pH Value on Stress Corrosion Cracking of X70 Pipeline Steel in Acidic Soil Environment

    Zhiyong LIU; Cuiwei DU; Xin ZHANG; Fuming WANG; Xiaogang LI

    2013-01-01

    The effect of pH value on the stress corrosion cracking (SCC) of API X70 pipeline steel in simulated acidic soil solutions was investigated by using slow strain rate test,electrochemical polarization curves,electrochemical impedance spectroscopy,and scanning electron microscopy.pH plays an important role in the susceptibility and electrochemical mechanism of SCC.The pH higher than 5 has no significant effect on electrochemical processes.By contrast,the pH lower than 5 intensifies cathodic hydrogen evolution reactions,thus increasing the cathodic current and corrosion potential.Under different pH values,the SCC mechanism of X70 pipeline steel varies among anodic dissolution (AD),hydrogen embrittlement (HE),and the combination of AD and HE (AD + HE) with variations of applied potential.At-850 mVSCE,the SCC mechanism is HE if pH is less than 4 or AD + HE if pH value is more positive.

  5. X70钢级大径厚比热煨弯管制造工艺研究%Research on Manufacturing Technology for X70 Grade Large Diameter-thickness Ratio Hot Bending Bends

    张海波; 彭立山; 白雷杰; 赵志伟; 刘旭; 巩忠旺

    2014-01-01

    针对X70钢级大径厚比热煨弯管的制造难点,合理改进了弯管机组设备,优化弯管成型工艺参数,精确测量和控制弯管煨制温度和速度,开发了一套完整的大径厚比弯管制造工艺,该工艺解决了大径厚比弯管成型后管体椭圆度超标和弯管综合力学性能差等问题。采用该工艺进行了单根和批量生产,产品符合伊拉克MOEP工程《弯管技术规格书》要求。%In this article,according to the manufacturing difficulties of X70 grade hot bending bends with large diameter-thickness ratio,it reasonably improved bends unit equipment,optimized bends forming process parameters,accurately measured and controlled the temperature and speed in bends forming process. A complete set of large diameter-thickness ratio bends manufacturing process was developed, it resolved some problems,including ovality of bends body exceeding the standard requirements,the comprehensive mechanic properties not good,and other manufacturing difficulties. It adopted the above manufacturing process to conduct single and bulk production, the products accord with the requirements of Iraq MOEP Project Technical Specification for Bending Bends.

  6. Static Recrystallized Grain Size of Coarse-Grained Austenite in an API-X70 Pipeline Steel

    Sha, Qingyun; Li, Guiyan; Li, Dahang

    2013-12-01

    The effects of initial grain size and strain on the static recrystallized grain size of coarse-grained austenite in an API-X70 steel microalloyed with Nb, V, and Ti were investigated using a Gleeble-3800 thermomechanical simulator. The results indicate that the static recrystallized grain size of coarse-grained austenite decreases with decreasing initial grain size and increasing applied strain. The addition of microalloying elements can lead to a smaller initial grain size for hot deformation due to the grain growth inhibition during reheating, resulting in decreasing of static recrystallized grain size. Based on the experimental data, an equation for the static recrystallized grain size was derived using the least square method. The grain sizes calculated using this equation fit well with the measured ones compared with the equations for fine-grained austenite and for coarse-grained austenite of Nb-V microalloyed steel.

  7. Correlation of microstructure and charpy impact properties in API X70 and X80 line-pipe steels

    This study aims at correlating microstructure and Charpy impact properties in high-toughness API X70 and X80 line-pipe steels. Three kinds of steels were fabricated by varying alloying elements and hot rolling conditions, and their microstructures and Charpy impact properties were investigated. In addition, their effective grain sizes were characterized by the electron back-scatter diffraction (EBSD) analysis. The Charpy impact test results indicated that the steels rolled in the single phase region had the higher upper shelf energy (USE) than the steel rolled in the two phase region because their microstructures were composed of acicular ferrites. In the X80 steel rolled in the single phase region, the decreased energy transition temperature (ETT) could be explained by the decrease in the overall effective grain size due to the presence of acicular ferrite having smaller effective grain size. Thus, it had excellent mechanical properties in yield and tensile strengths, absorbed energy, and transition temperature, except in ductility

  8. The effect of processing parameters on the dynamic recrystallisation behaviour of API-X70 pipeline steel

    Al Shahrani, Abdullah, E-mail: amfa065@uowmail.edu.au [School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, New South Wales 2522 (Australia); Yazdipour, Nima; Dehghan-Manshadi, Ali [School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, New South Wales 2522 (Australia); Gazder, Azdiar A. [School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, New South Wales 2522 (Australia); Electron Microscopy Centre, University of Wollongong, New South Wales 2519 (Australia); Cayron, Cyril [CEA, DRT, LITEN, Minatec, 38054 Grenoble Cedex 9 (France); Pereloma, Elena V. [School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, New South Wales 2522 (Australia); Electron Microscopy Centre, University of Wollongong, New South Wales 2519 (Australia)

    2013-05-15

    The effect of deformation temperature and strain rate on the dynamic recrystallisation (DRX) behaviour of X70 pipeline steel was investigated. DRX parameters such as the critical and peak stresses and strains as well as the deformation activation energy were determined in the temperature range between 925 °C and 1125 °C for strain rates of 0.1, 1 and 5 s{sup −1}. The relationship between the peak stresses and strains with the Zener–Hollomon parameter was determined. The dynamically recrystallised volume fraction was computed as a function of the different temperatures and strain rates. The APRGE software was applied for the first time on electron back-scattering diffraction data of dynamically recrystallised microstructures in order to reconstruct the prior austenite from the as-quenched martensite phase. The dynamically recrystallised flow stress curves and microstructure were also predicted using cellular automata modelling. The results show an earlier onset of DRX with a decrease in strain rate or an increase in deformation temperature. The dynamically recrystallised grain size is also found to decrease with an increase in strain rate and a lowering of deformation temperature.

  9. The effect of processing parameters on the dynamic recrystallisation behaviour of API-X70 pipeline steel

    The effect of deformation temperature and strain rate on the dynamic recrystallisation (DRX) behaviour of X70 pipeline steel was investigated. DRX parameters such as the critical and peak stresses and strains as well as the deformation activation energy were determined in the temperature range between 925 °C and 1125 °C for strain rates of 0.1, 1 and 5 s−1. The relationship between the peak stresses and strains with the Zener–Hollomon parameter was determined. The dynamically recrystallised volume fraction was computed as a function of the different temperatures and strain rates. The APRGE software was applied for the first time on electron back-scattering diffraction data of dynamically recrystallised microstructures in order to reconstruct the prior austenite from the as-quenched martensite phase. The dynamically recrystallised flow stress curves and microstructure were also predicted using cellular automata modelling. The results show an earlier onset of DRX with a decrease in strain rate or an increase in deformation temperature. The dynamically recrystallised grain size is also found to decrease with an increase in strain rate and a lowering of deformation temperature

  10. Stress corrosion cracking of X70 pipeline steel in near-neutral pH soil solution

    Fang, B.Y.; Wang, J.Q.; Han, E.H.; Zhu, Z.Y.; Ke, W. [Chinese Academy of Sciences, Shenyang (China). State Key Laboratory for Corrosion and Protection, Inst. of Metal Research

    2004-07-01

    Near-neutral pH stress corrosion cracking (SCC) is characterized by wide transgranular cracks with quasi-cleavage on the fracture surface, and there is usually little evidence of general or lateral corrosion. Near-neutral pH SCC is related to dissolution and hydrogen ingress into steel pipes because discharged atomic hydrogen can enter the steel so that cracks are initiated or grown by a combination of dissolution and hydrogen-embrittlement. In this study, the SCC cracking behaviour of an X70 pipeline was investigated using slow strain rate tests (SSRT) and cyclic loading at high R and low frequency in a near-neutral pH soil solution saturated with 5 per cent carbon dioxide (CO{sub 2}) and 95 per cent nitrogen (N{sub 2}). Potentiodynamic polarization analyses and electrochemical impedance spectrum (EIS) analyses were also conducted in order to examine the effect of the concentration of bicarbonate, bubbled gas and the addition of chloride ions on polarization behaviour. Results of the SSRT tests showed that transgranular SCC occurred in the soil solution. Crack initiation was associated with pitting. The pipe's susceptibility to SCC increased with decreases in applied electrochemical potential and strain rate. Cyclic loading tests showed that crack propagation processes were dominated by SCC. At high R and low frequencies, SCC was observed on fatigued, pre-cracked specimens. Results of the electrochemical tests showed that polarization behaviours were influenced by the concentrations of bicarbonate, bubbled gas, and the addition of chloride ions. It was concluded that the addition of chloride ion can influence film stability on pipeline specimen surfaces. 22 refs., 2 tabs., 8 figs.

  11. RECRYSTALLIZATION BEHAVIOR AND PRIOR AUSTENITE GRAIN BOUNDARY CORROSION IN THE PLANE STRAIN COMPRESSION CONDITION FOR A LOW CARBON X70 PIPELINE STEEL

    Y.H. Li; J. Wang; Y.S. Li; Y. Y. Shan

    2004-01-01

    Recrystallization behavior of a low carbon X70 pipeline steel was studied in the plane strain compression condition. It was found that the dynamic recovery but no dynamic recrystallization occurred in the current experimental condition. A method for examining the prior austenite grain boundary corrosion was supposed.

  12. New calibration method for high and low triaxiality and validation on SENT specimens of API X70

    The determination of the exact mechanical properties of material is essential for an optimal and safe design of linepipes. It is especially important for the prevention of over-engineering and the reliable assessment of complex accidental loading, such as extreme bending due to loss of buoyancy of support, or abrupt ground movement. Currently, the focus of research in offshore deepwater installations and linepipes is towards pre-cracked structures with high triaxiality stress states and complex loading histories. At the same time, low triaxiality stress states must be correctly studied in order to represent shear dominated failure in pipes. A comprehensive experimental and numerical program was undertaken to determine the mechanical properties of the traditional API X70 grade of steel. The material was characterized for anisotropic plasticity, fracture initiation and uncracked ductility for various states of stress. The same material was also used for pre-cracked fracture toughness assessment. The experimental program included flat and round specimens. The first type of tests on flat butterfly-shaped, central hole, notched and circular disk specimens; were selected to address the low stress triaxiality range. Tests on round notched bar specimens and SENT fracture mechanics tests extended the characterization and verification process to higher stress triaxiality values. This program covered a wide range of stress conditions and demonstrated their effect on the material resistance to crack extension. Each test conducted was numerically simulated using solid finite element models, matching the exact geometric and loading history features. The numerical simulation provided information on the local stress and strain fields around the location of the potential or existing cracks. Based on the above hybrid experimental/numerical technique tailored for pipe applications, the MMC fracture model was calibrated. The model relates the material ductility not only to stress

  13. Fragilización por Hidrógeno de los Aceros API 5L X60 y API 5L X80 Hydrogen Embrittlement of API 5L X60 and API 5L X80 Steels

    Bruno A Araújo; Jorge A Palma; Vilar, Eudésio O.; Silva, Antonio A.

    2011-01-01

    Se ha determinado el comportamiento mecánico de los aceros API 5L grados X60 y X80, fragilizados por hidrógeno ambiental y por hidrógeno interno. El potencial y la densidad de corriente para la generación del hidrógeno fueron determinados por polarización potenciodinámica, y el tiempo de saturación estimado a partir de datos de difusividad y solubilidad obtenidos en ensayos de permeación con una célula electroquímica. La carga de hidrógeno para reproducir las condiciones de la fragilización p...

  14. Fragilización por Hidrógeno de los Aceros API 5L X60 y API 5L X80 Hydrogen Embrittlement of API 5L X60 and API 5L X80 Steels

    Bruno A Araújo

    2011-01-01

    Full Text Available Se ha determinado el comportamiento mecánico de los aceros API 5L grados X60 y X80, fragilizados por hidrógeno ambiental y por hidrógeno interno. El potencial y la densidad de corriente para la generación del hidrógeno fueron determinados por polarización potenciodinámica, y el tiempo de saturación estimado a partir de datos de difusividad y solubilidad obtenidos en ensayos de permeación con una célula electroquímica. La carga de hidrógeno para reproducir las condiciones de la fragilización por hidrógeno ambiental y fragilización por hidrógeno interno fue realizada generando un gradiente de concentración para el primer caso, y generando gradientes de concentración y de tensiones para el segundo. Luego de los ensayos de tracción se verificò que, en las condiciones definidas en este trabajo, el modo de fractura en ambos tipos de fragilización fue predominantemente dúctil. Ademàs, los dos aceros mostraron una susceptibilidad baja o moderada a la fragilización por hidrógeno ambiental, no siendo susceptibles a la fragilización por hidrógeno interno.The mechanical behavior of the API 5L X60 and X80 grade steels under environmental hydrogen embrittlement effect and internal hydrogen embrittlement effect was determined. The potential and current density for hydrogen generation were determined by potentiodynamic polarization. The saturation time was estimated from diffusivity and solubility data, obtained from permeation tests with an electrochemical cell. The hydrogen charge to reproduce the conditions of the environmental hydrogen embrittlement and the internal hydrogen embrittlement was performed by generating a concentration gradient in the first case, and a concentration and stress gradients in the second case. After the tensile tests it was verified that in the defined tests conditions, the fracture mode in both types of embrittlement was predominantly ductile. Also, both steels showed low or moderate susceptibility to

  15. Expression of CDC5L is associated with tumor progression in gliomas.

    Chen, Wenjuan; Zhang, Li; Wang, Yan; Sun, Jie; Wang, Donglin; Fan, Shaochen; Ban, Na; Zhu, Junya; Ji, Bin; Wang, Yuchan

    2016-03-01

    Cell division cycle 5-like (CDC5L) protein is a cell cycle regulator of the G2/M transition and has been reported to participate in the catalytic step of pre-messenger RNA (mRNA) splicing and DNA damage repair. Recently, it was also found to act as a candidate oncogene in osteosarcoma and cervical tumors. However, the role of CDC5L expression in tumor biology was still unclear. Here, we analyzed the expression and clinical significance of CDC5L in gliomas. The expression of CDC5L in fresh glioma tissues and paraffin-embedded slices was evaluated by western blot and immunohistochemistry, respectively. We found that CDC5L was highly expressed in glioma tissues. The expression of CDC5L was significantly associated with glioma pathology grade and Ki-67 expression. Univariate and multivariate analyses showed that high CDC5L expression was an independent prognostic factor for glioma patients' survival. To determine whether CDC5L could regulate the proliferation of glioma cells, we transfected glioma cells with interfering RNA target CDC5L, then investigated cell proliferation with cell counting kit (CCK)-8, flow cytometry assays and colony formation analyses. Our results indicated that knockdown of CDC5L would inhibit proliferation of glioma cells. Besides, reduced expression of CDC5L could induce the apoptosis of glioma cells. These findings suggested that CDC5L might play an important role in glioma and thus be a promising therapeutic target of glioma. PMID:26490980

  16. Effects of Dynamic Strain Hardening Exponent on Abnormal Cleavage Fracture Occurring During Drop Weight Tear Test of API X70 and X80 Linepipe Steels

    Kang, Minju; Kim, Hyunmin; Lee, Sunghak; Shin, Sang Yong

    2014-02-01

    In this study, drop weight tear tests (DWTT) were conducted on API X70 and X80 linepipe steels fabricated with various compositions and rolling and cooling conditions in order to correlate the strain hardening with the abnormal cleavage fracture occurring in the hammer-impacted area. Area fractions of fracture modes were measured from fractured DWTT specimens, and the measured data were analyzed in relation to microstructures, Charpy impact energy, and strain hardening. All the steels consisted of fine acicular ferrite, together with some bainitic ferrite, granular bainite, and martensite-austenite constituent. As the volume fraction of acicular ferrite increased, the area fraction of DWTT abnormal cleavage fracture decreased because the toughness of acicular ferrite was higher than other microstructures. The area fraction of abnormal cleavage fracture was weakly related with strain hardening exponents obtained from the quasi-static tensile and compressive tests, but showed better correlation with those obtained from the dynamic compressive test. This tendency could be more clearly observed when steels having similar Charpy impact energy levels were grouped. Since the DWTT was performed under a dynamic loading condition, thus, the abnormal cleavage fracture behavior should be related with the strain hardening analyzed under a dynamic loading condition.

  17. Effect of Strain Rate on Cathodic Reaction During Stress Corrosion Cracking of X70 Pipeline Steel in a Near-Neutral pH Solution

    Liu, Z. Y.; Li, X. G.; Cheng, Y. F.

    2011-10-01

    The effect of strain rate on cathodic reactions of X70 pipeline steel during stress corrosion cracking in a near-neutral pH solution was investigated by electrochemical impedance spectroscope and potentiodynamic polarization curve measurements as well as slow strain rate tests. A local additional potential model was used to understand mechanistically the role of strain rate in electrochemical cathodic reaction. It was found that an application of elastic stress would not affect the electrochemical stable state of the steel specimen at a macroscopic scale. Under a weak cathodic polarization, the interfacial charge-transfer process occurring on steel contains both cathodic and anodic reactions. Since the anodic reaction process is still significant, localized dissolution could occur even at such a cathodic potential, resulting in generation of corrosion pits. These pits could be the start sites to initiate stress corrosion cracks. Strain rate affects the corrosion reaction, which is associated with the generation of dislocation emergence points and slip steps on the specimen surface, resulting in a negative local additional potential to enhance the cathodic reaction locally.

  18. Effects of corrosion product deposit on the subsequent cathodic and anodic reactions of X-70 steel in near-neutral pH solution

    Meng, G.Z. [Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, AB, T2N 1N4 (Canada); College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001 (China); Zhang, C. [Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, AB, T2N 1N4 (Canada); Center of Corrosion and Protection, University of Science and Technology Beijing, Beijing 100083 (China); Cheng, Y.F. [Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, AB, T2N 1N4 (Canada)], E-mail: fcheng@ucalgary.ca

    2008-11-15

    The effects of corrosion product deposit on the subsequent anodic and cathodic reactions of X-70 steel in a near-neutral pH solution were investigated by localized electrochemical impedance spectroscopy (LEIS), scanning vibrating micro-electrode (SVME) and macroscopic EIS measurements as well as surface analysis technique. It is found that the deposit layer formed on the steel surface is porous, non-compact in nature. The presence of a corrosion product layer would enhance adsorption, but significantly inhibit absorption and permeation of hydrogen atoms into steel. It is due to the porous structure of the deposit that generates a spatial separation of cathodic and anodic reaction sites, resulting in an increased effective surface area for hydrogen adsorption and, simultaneously, a 'blocking' effect on hydrogen absorption and permeation. The deposit enhances greatly anodic dissolution of the steel, which is attributed to the adsorption of the intermediate species and the resultant 'self-catalytic' mechanism for corrosion of the steel in near-neutral pH solution. In the presence of corrosion product deposit on the pipeline steel surface, pipeline corrosion, especially pitting corrosion, is expected to be enhanced. Stress corrosion cracks could initiate from the corrosion pits that form under deposit. However, deposit does not contribute to hydrogen permeation, although the hydrogen evolution is enhanced.

  19. Evolution of weld metal microstructure in shielded metal arc welding of X70 HSLA steel with cellulosic electrodes: A case study

    Ghomashchi, Reza, E-mail: reza.ghomashchi@adelaide.edu.au; Costin, Walter; Kurji, Rahim

    2015-09-15

    The microstructure of weld joint in X70 line pipe steel resulted from shielded metal arc welding with E6010 cellulosic electrodes is characterized using optical and electron microscopy. A range of ferritic morphologies have been identified ranging from polygonal inter- and intra-prior austenite grains allotriomorphic, idiomorphic ferrites to Widmanstätten, acicular and bainitic ferrites. Electron Backscatter Diffraction (EBSD) analysis using Image Quality (IQ) and Inverse Pole Figure (IPF) maps through superimposition of IQ and IPF maps and measurement of percentages of high and low angle grain boundaries was identified to assist in differentiation of acicular ferrite from Widmanstätten and bainitic ferrite morphologies. In addition two types of pearlitic structures were identified. There was no martensite detected in this weld structure. The morphology, size and chemistry of non-metallic inclusions are also discussed briefly. - Highlights: • Application of EBSD reveals orientation relationships in a range of phases for shielded metal arc welding of HSLA steel. • Nucleation sites of various ferrite morphologies identified • Formation of upper and lower bainite and their morphologies.

  20. Evolution of weld metal microstructure in shielded metal arc welding of X70 HSLA steel with cellulosic electrodes: A case study

    The microstructure of weld joint in X70 line pipe steel resulted from shielded metal arc welding with E6010 cellulosic electrodes is characterized using optical and electron microscopy. A range of ferritic morphologies have been identified ranging from polygonal inter- and intra-prior austenite grains allotriomorphic, idiomorphic ferrites to Widmanstätten, acicular and bainitic ferrites. Electron Backscatter Diffraction (EBSD) analysis using Image Quality (IQ) and Inverse Pole Figure (IPF) maps through superimposition of IQ and IPF maps and measurement of percentages of high and low angle grain boundaries was identified to assist in differentiation of acicular ferrite from Widmanstätten and bainitic ferrite morphologies. In addition two types of pearlitic structures were identified. There was no martensite detected in this weld structure. The morphology, size and chemistry of non-metallic inclusions are also discussed briefly. - Highlights: • Application of EBSD reveals orientation relationships in a range of phases for shielded metal arc welding of HSLA steel. • Nucleation sites of various ferrite morphologies identified • Formation of upper and lower bainite and their morphologies

  1. X70级φ1016 mm×17.5 mm天然气管道环焊缝缺陷剖析%Analysis on Circumferential Weld Defects of X70 φ 1 016 mm×17.5 mm Gas Pipeline

    黄磊; 李记科; 王长安; 高建忠

    2013-01-01

    针对某天然气管道工程用X70级φ1 016 mm×17.5 mm焊管环焊缝焊接接头出现的缺陷,应用超声波检测和射线检测方法对缺陷进行了定位和定量检测,并通过金相分析、扫描电镜分析了缺陷中材料的性质.分析结果表明,此缺陷为第一次焊接过程中产生的焊渣在第二次补焊时未清理干净而产生的坡口未熔合.同时,分析了由于射线检测透照角度不同造成的射线底片影像异常现象.最后给出了焊接和无损检测过程中的一些合理化建议.%In this paper,aimed at the defects appeared in circumferential weld of X70 φ 1 016 mm×17.5 mm welded joint in some gas pipeline project,the positioning and quantitative detection for defects were carried out by ultrasonic inspection and X-ray inspection,and the material properties of defects were analyzed through metallographic analysis and SEM.The results showed that this kind of defect is incomplete fusion groove,which occurred in the first welding pass and didn't be cleaned completely after the second repair welding.At the same time,the abnormal phenomena of X-ray radiograph caused by different transillumination angle.Finally,some reasonable proposals in the process of welding and non-destructive test were put forward.

  2. Effect of Celluclast 1.5L on the Physicochemical Characterization of Gold Kiwifruit Pectin

    Mawson, John A.; Charles S. Brennan; Kelvin K. T. Goh; Lara Matia-Merino; Oni Yuliarti

    2011-01-01

    The effects of Celluclast 1.5L concentration on the physicochemical characterization of gold kiwifruit pectin was evaluated. Varying the enzyme concentration affected the pectin yield and pectin physicochemical properties. The viscosity of extracted pectin was largely dependent on the enzyme concentration. Celluclast 1.5L with medium concentration exhibited the highest viscosity. Varying the enzyme concentration also influenced the molecular weight distribution. High molecular weight (M w) pe...

  3. Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution.

    Xu, Wenjuan; Jing, Linlin; Wang, Quanshi; Lin, Chung-Chih; Chen, Xiaoting; Diao, Jianxin; Liu, Yuanliang; Sun, Xuegang

    2015-10-01

    Intrinsic apoptosis eliminates cells with damaged DNA and cells with dysregulated expression of oncogene. PGAM5, a member of the phosphoglycerate mutase family, has two splicing variants: PGAM5L (the long form) and PGAM5S (the short form). It has been well established that PGAM5 is at the convergent point of multiple necrosis pathways. However, the role of PGAM5 in intrinsic apoptosis is still controversial. Here we report that the PGAM5L, but not PGAM5S is a prerequisite for the activation of Bax and dephosphorylation of Drp1 in arenobufagin and staurosporine induced intrinsic apoptosis. Knockdown of PGAM5L inhibits the translocation of Bax to the mitochondria and reduces mitochondrial fission. The interaction between PGAM5L and Drp1 was observed in both arenobufagin and staurosporine treated HCT116 cells, but not in HCT116 Bax(-/-) cells. Bax transfection rescues the formation of the triplex in both arenobufagin and staurosporine stimulated HCT116 Bax(-/-) cells. Arenobufagin shows remarkable anti-cancer effects both in orthotropic and heterotropic CRC models and demonstrates less toxic effects as compared with that of cisplatin. Bax-PGAM5L-Drp1 complex is detected in arenobufagin and staurosporine treated CRC cells in vitro and in arenobufagin and cisplatin treated tumor in vivo as well. In summary, our results demonstrate that Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution. PMID:26356820

  4. 热压缩变形参数对海底用 X70管线钢再结晶行为的影响%Effects of Hot Compression Deformation Parameters on Recrystallization Behavior of X70 Pipeline Steel Used in Submarine

    王良塑; 贾书君; 刘清友; 项金钟

    2016-01-01

    采用热模拟试验机研究了应变速率为1 s-1时变形温度、变形量和变形后保温时间对海底用 X70管线钢再结晶行为的影响.结果表明:在变形量为25%的条件下,试验钢发生动态再结晶的变形温度为1000~1020℃,奥氏体晶粒可细化到33μm 左右;在变形温度为980℃的条件下,发生动态再结晶的变形量为25%~30%,当变形量达到30%时,再结晶基本完成,晶粒尺寸随变形量增大而减小;在变形温度为980℃、变形量为25%的条件下变形完成保温5 s后,试验钢开始发生静态再结晶,保温30 s 后静态再结晶基本完成,此时晶粒尺寸最小,为41μm.%Effects of deformation temperature, deformation and holding time after deformation on recrystallization behavior of X70 pipeline steel used in submarine were studied by thermal simulator.The results show that when deformation was 25%,dynamic recrystallization temperature of the tested steel was 1 000-1 020 ℃, austenite grain size could be refined to 33 μm.Under the condition of deformation temperatue of 980 ℃,dynamic recrystallization happened at deformation range of 25%-30%,dynamic recrystallization completed basically when deformation was 30%.Grain size decreased with the increase of deformation.When deformation temperature was 980 ℃,deformation was 25% and holding time was 5 s,tested steels started to static recrystallization,the static recrystallization completed basically after holding 30 s.At the moment,austenite grain size was minimum and up to 41 μm.

  5. Large scale validation of the M5L lung CAD on heterogeneous CT datasets

    Purpose: M5L, a fully automated computer-aided detection (CAD) system for the detection and segmentation of lung nodules in thoracic computed tomography (CT), is presented and validated on several image datasets. Methods: M5L is the combination of two independent subsystems, based on the Channeler Ant Model as a segmentation tool [lung channeler ant model (lungCAM)] and on the voxel-based neural approach. The lungCAM was upgraded with a scan equalization module and a new procedure to recover the nodules connected to other lung structures; its classification module, which makes use of a feed-forward neural network, is based of a small number of features (13), so as to minimize the risk of lacking generalization, which could be possible given the large difference between the size of the training and testing datasets, which contain 94 and 1019 CTs, respectively. The lungCAM (standalone) and M5L (combined) performance was extensively tested on 1043 CT scans from three independent datasets, including a detailed analysis of the full Lung Image Database Consortium/Image Database Resource Initiative database, which is not yet found in literature. Results: The lungCAM and M5L performance is consistent across the databases, with a sensitivity of about 70% and 80%, respectively, at eight false positive findings per scan, despite the variable annotation criteria and acquisition and reconstruction conditions. A reduced sensitivity is found for subtle nodules and ground glass opacities (GGO) structures. A comparison with other CAD systems is also presented. Conclusions: The M5L performance on a large and heterogeneous dataset is stable and satisfactory, although the development of a dedicated module for GGOs detection could further improve it, as well as an iterative optimization of the training procedure. The main aim of the present study was accomplished: M5L results do not deteriorate when increasing the dataset size, making it a candidate for supporting radiologists on large

  6. Large scale validation of the M5L lung CAD on heterogeneous CT datasets

    Lopez Torres, E., E-mail: Ernesto.Lopez.Torres@cern.ch, E-mail: cerello@to.infn.it [CEADEN, Havana 11300, Cuba and INFN, Sezione di Torino, Torino 10125 (Italy); Fiorina, E.; Pennazio, F.; Peroni, C. [Department of Physics, University of Torino, Torino 10125, Italy and INFN, Sezione di Torino, Torino 10125 (Italy); Saletta, M.; Cerello, P., E-mail: Ernesto.Lopez.Torres@cern.ch, E-mail: cerello@to.infn.it [INFN, Sezione di Torino, Torino 10125 (Italy); Camarlinghi, N.; Fantacci, M. E. [Department of Physics, University of Pisa, Pisa 56127, Italy and INFN, Sezione di Pisa, Pisa 56127 (Italy)

    2015-04-15

    Purpose: M5L, a fully automated computer-aided detection (CAD) system for the detection and segmentation of lung nodules in thoracic computed tomography (CT), is presented and validated on several image datasets. Methods: M5L is the combination of two independent subsystems, based on the Channeler Ant Model as a segmentation tool [lung channeler ant model (lungCAM)] and on the voxel-based neural approach. The lungCAM was upgraded with a scan equalization module and a new procedure to recover the nodules connected to other lung structures; its classification module, which makes use of a feed-forward neural network, is based of a small number of features (13), so as to minimize the risk of lacking generalization, which could be possible given the large difference between the size of the training and testing datasets, which contain 94 and 1019 CTs, respectively. The lungCAM (standalone) and M5L (combined) performance was extensively tested on 1043 CT scans from three independent datasets, including a detailed analysis of the full Lung Image Database Consortium/Image Database Resource Initiative database, which is not yet found in literature. Results: The lungCAM and M5L performance is consistent across the databases, with a sensitivity of about 70% and 80%, respectively, at eight false positive findings per scan, despite the variable annotation criteria and acquisition and reconstruction conditions. A reduced sensitivity is found for subtle nodules and ground glass opacities (GGO) structures. A comparison with other CAD systems is also presented. Conclusions: The M5L performance on a large and heterogeneous dataset is stable and satisfactory, although the development of a dedicated module for GGOs detection could further improve it, as well as an iterative optimization of the training procedure. The main aim of the present study was accomplished: M5L results do not deteriorate when increasing the dataset size, making it a candidate for supporting radiologists on large

  7. Relationship of C5L2 Receptor to Skeletal Muscle Substrate Utilization

    Roy, Christian; Paglialunga, Sabina; Schaart, Gert; Moonen-Kornips, Esther; Meex, Ruth C.; Phielix, Esther; Hoeks, Joris; Hesselink, Matthijs K. C.; Cianflone, Katherine; Schrauwen, Patrick

    2013-01-01

    Objective To investigate the role of Acylation Stimulating Protein (ASP) receptor C5L2 in skeletal muscle fatty acid accumulation and metabolism as well as insulin sensitivity in both mice and human models of diet-induced insulin resistance. Design and Methods Male wildtype (WT) and C5L2 knockout (KO) mice were fed a low (LFD) or a high (HFD) fat diet for 10 weeks. Intramyocellular lipid (IMCL) accumulation (by oil red O staining) and beta-oxidation HADH enzyme activity were determined in ske...

  8. Effect of Celluclast 1.5L on the Physicochemical Characterization of Gold Kiwifruit Pectin

    Yuliarti, Oni; Matia-Merino, Lara; Goh, Kelvin K. T.; Mawson, John A.; Brennan, Charles S.

    2011-01-01

    The effects of Celluclast 1.5L concentration on the physicochemical characterization of gold kiwifruit pectin was evaluated. Varying the enzyme concentration affected the pectin yield and pectin physicochemical properties. The viscosity of extracted pectin was largely dependent on the enzyme concentration. Celluclast 1.5L with medium concentration exhibited the highest viscosity. Varying the enzyme concentration also influenced the molecular weight distribution. High molecular weight (Mw) pectin (1.65 × 106 g/mol) was obtained when the medium concentration was used. Overall, the study clearly reflects the importance of taking into consideration the amount of cellulytic enzyme added in order to determine the final quality of pectin. PMID:22072895

  9. Effect of Celluclast 1.5L on the Physicochemical Characterization of Gold Kiwifruit Pectin

    John A. Mawson

    2011-09-01

    Full Text Available The effects of Celluclast 1.5L concentration on the physicochemical characterization of gold kiwifruit pectin was evaluated. Varying the enzyme concentration affected the pectin yield and pectin physicochemical properties. The viscosity of extracted pectin was largely dependent on the enzyme concentration. Celluclast 1.5L with medium concentration exhibited the highest viscosity. Varying the enzyme concentration also influenced the molecular weight distribution. High molecular weight (Mw pectin (1.65 × 106 g/mol was obtained when the medium concentration was used. Overall, the study clearly reflects the importance of taking into consideration the amount of cellulytic enzyme added in order to determine the final quality of pectin.

  10. Comparing responsiveness of the EQ-5D-5L, EQ-5D-3L and EQ VAS in stroke patients

    D. Golicki (Dominik); M. Niewada (Maciej); A. Karlińska (Anna); J. Buczek (Julia); A. Kobayashi (Adam); M.F. Janssen (Mathieu); A.S. Pickard (Simon)

    2015-01-01

    textabstractAims: To date, evidence to support the construct validity of the EQ-5D-5L has primarily focused on cross-sectional data. The aims of this study were to examine the responsiveness of EQ-5D-5L in patients with stroke and to compare it with responsiveness of EQ-5D-3L and visual analogue sca

  11. Avaliação da perfuração na soldagem em operação pelo processo MIG/MAG de dutos de alta resistência e baixa espessura

    Aldo S. Pereira

    2013-09-01

    Full Text Available O objetivo deste trabalho foi o desenvolvimento de reparo em dutos com pequena espessura (3,0 e 3,2 mm, fabricados em aços de alta resistência (API 5L X70 e em tubo ASTM 106 Grau B de forma a minimizar o risco de perfuração. Para o experimento, foi construída uma bancada de testes com ajuste variável de vazão e pressão do fluido, a saber, vazões de 20 l/min, 40 l/min e 80 l/min e pressões de 2 bar e 5 bar. Foram realizadas soldagens na direção longitudinal sobre tubos contendo água como fluido interno, utilizando-se o processo semiautomático MIG/MAG (GMAW com posterior avaliação do aspecto da menor penetração do cordão. Desta forma, foram empregadas duas técnicas de soldagem, puxando e empurrando a poça de fusão, assim como os modos de transferência metálica em curto circuito ou em corrente pulsada. No estudo das condições limites para a ocorrência de perfuração foram pesquisados parâmetros de soldagem em função de condições específicas de vazão e de pressão. A temperatura interna da parede da tubulação foi determinada através de uma solução analítica para a transferência de calor na soldagem. Os resultados mostraram que para o processo MIG/MAG com corrente pulsada e com a técnica empurrando a poça de fusão, mantidas todas as outras variáveis de soldagem fixas, há pequena penetração do cordão de solda. Além disso, os níveis de energia de soldagem para a ocorrência da perfuração revelaram-se superiores aos obtidos na literatura para o processo SMAW, indicando o processo como robusto e apropriado para soldagem de reparo em operação.

  12. Soldagem em operação de dutos de alta resistência e baixa espessura com ênfase nas trincas a frio In-service welding of pipelines in high strength low thickness with emphasis on cold cracks

    Aldo Santos Pereira

    2012-06-01

    Full Text Available O objetivo deste trabalho foi avaliar a ocorrência de trincas a frio quando da soldagem de dutos em operação. Foram executados dois conjuntos de experimentos: o primeiro denominado de experimento "F", em que foi variada a folga entre a calha e o tubo, e utilizados metal de base e de adição de alto carbono equivalente; o segundo denominado de experimento "R", em que foi imposta alta restrição à junta soldada e, promovido o resfriamento rápido mediante fluxo de água no interior do tubo. Foram feitas as soldagens com os seguintes processos e materiais: processo eletrodo revestido (SMAW, tubo e calha em aço ASTM A 335 P5, metal de adição AWS E 8018-B8 (experimento "F". Processos MIG/MAG pulsado (GMAW-P e arame tubular auto-protegido (FCAW-S, tubo e calha em aço API 5L X70, metais de adição AWS ER 80S-G e AWS E 71T-11, respectivamente (experimento "R". Para detectar as trincas a frio foram realizados exame visual e a inspeção com líquidos penetrantes. Adicionalmente as soldas foram avaliadas por macrografia e medição de dureza. Não foram detectadas trincas, apesar da utilização de metais de base e de adição com alto carbono equivalente e da junta com alta restrição, com o objetivo de aumentar as tensões. Admite-se que não houve fissuração devido ao uso de processos e/consumíveis com baixo teor de hidrogênio.The aim of this study was to evaluate the occurence of cold cracks associated with in-service welding of pipelines. Two sets of experiments were performed : the first of them was called experiment "F", where the gap between sleeve and pipe was varied and base and weld metal of high carbon equivalent were used, the second set of experiment was denominated "R", when higher restriction was imposed to the welded joint, which was simultaneously more rapid cooled by water flow within the pipe. The welds were made ​​with the following procedures and materials: shielded metal arc welding (SMAW of tube and pipeline

  13. Application of Celluclast 1.5L in apple pectin extraction.

    Wikiera, Agnieszka; Mika, Magdalena; Starzyńska-Janiszewska, Anna; Stodolak, Bożena

    2015-12-10

    Pectins were extracted from apple pomace with Celluclast 1.5L at a dose of 25, 50 and 75 μl per 1g of material. In obtained pectin, the galacturonic acid (GalA) content, the neutral sugars (NS) profile, the degree of methylation (DM) and acetylation (DAc), the molecular mass, protein, ash and polyphenol levels as well as antioxidant and antitumor activity were determined. The lowest dose of enzymatic preparation resulted in the yield of pectin isolation comparable with acidic treatment (15.3%). Application of higher dose caused further, almost 4% increase in polymer recovery. Enzymatically isolated pectin was characterised by larger molecular mass and contained more GalA of higher DM and DAc than polymer extracted with acid. It was also richer in protein and polyphenols, and had different NS profile, which resulted in higher antiradical activity as well as the ability to inhibit the proliferation and invasion of Caco-2 adenocarcinoma cells. PMID:26428122

  14. 3.5L V6 EcoBoost - democratization of sustainable engine technology

    Kapp, Daniel; Schamel, Andreas; Hinds, Brett; Weaver, Corey [Ford Motor Co., Dearborn, MI (United States)

    2008-07-01

    The North American automotive industry is presently facing the challenge of a recently signed energy bill increasing corporate average fuel economy standards to 35 mpg (6.7 L/km) by 2020, inclusive of cars and trucks. The passing of this bill is coincident with crude oil costs hovering in the $130USD / barrel range, retail gasoline costs in the $4USD / gallon range, and mounting evidence on CO2 emissions and global warming. Ford Motor Company has anticipated these trends, has invested in the development of fuel efficient engine technologies, and is now deploying these technologies in volume to deliver both a meaningful and sustainable response to the above challenges. Leading the deployment curve is a technology publically announced as EcoBoost, representing the application of direct fuel injection and turbocharging to an advanced gasoline engine. Ford has previously reported the fundamentals of this technology which enables a significant fuel economy improvement via engine downsizing, and a significant performance improvement via engine dynamic response. As applied to 14 and V6 engine architectures, Ford has announced plans to deploy up to 750,000 EcoBoost engines worldwide by 2013 CY, with first application in the form of a 3.5L V6 EcoBoost engine in the 2010 MY Lincoln MKS luxury sedan. This paper summaries the development of the 3.5L V6 EcoBoost engine and its associated as-installed systems. Combustion, fuel, boost, and power conversion systems are discussed in detail with emphasis on the efficiency and value of these systems which enable a singular engine design to be applied across a wide range of applications. Engine performance and fuel economy assessments are also discussed and compared to conventional gasoline engines. (orig.)

  15. Independent chromatin binding of ARGONAUTE4 and SPT5L/KTF1 mediates transcriptional gene silencing.

    M Jordan Rowley

    2011-06-01

    Full Text Available Eukaryotic genomes contain significant amounts of transposons and repetitive DNA elements, which, if transcribed, can be detrimental to the organism. Expression of these elements is suppressed by establishment of repressive chromatin modifications. In Arabidopsis thaliana, they are silenced by the siRNA-mediated transcriptional gene silencing pathway where long non-coding RNAs (lncRNAs produced by RNA Polymerase V (Pol V guide ARGONAUTE4 (AGO4 to chromatin and attract enzymes that establish repressive chromatin modifications. It is unknown how chromatin modifying enzymes are recruited to chromatin. We show through chromatin immunoprecipitation (ChIP that SPT5L/KTF1, a silencing factor and a homolog of SPT5 elongation factors, binds chromatin at loci subject to transcriptional silencing. Chromatin binding of SPT5L/KTF1 occurs downstream of RNA Polymerase V, but independently from the presence of 24-nt siRNA. We also show that SPT5L/KTF1 and AGO4 are recruited to chromatin in parallel and independently of each other. As shown using methylation-sensitive restriction enzymes, binding of both AGO4 and SPT5L/KTF1 is required for DNA methylation and repressive histone modifications of several loci. We propose that the coordinate binding of SPT5L and AGO4 creates a platform for direct or indirect recruitment of chromatin modifying enzymes.

  16. API Spec5L(44版)关于材料及试验的变化%Changes of Materials and Tests in 44th Edition of Standard API Spec 5L

    王德林; 同建辉; 孙宏; 崔明亮

    2011-01-01

    针对API Spec 5L(44版)标准,简要分析了API 5L(44版)标准对于材料与理化试验方面与前一版本的变化.新版API 5L标准相比以前版本更加精简,实际使用更方便,在理化试验方面细节上变化较大,在焊管的实际生产应用中应予以注意.

  17. Quality of life profile and psychometric properties of the EQ-5D-5L in HIV/AIDS patients

    Tran Bach

    2012-11-01

    Full Text Available Abstract Objectives We assessed health-related quality of life (HRQOL, its associated factors, and examined measurement properties of the EuroQol - 5 Dimensions - 5 Levels (EQ-5D-5L in HIV/AIDS patients. Methods A cross-sectional multi-site survey was conducted in 1016 patients (age: 35.4 ± 7.0 years; 63.8% male in three epicenters of Vietnam. Internal consistency reliability, convergent validity, and discriminative validity of the EQ-5D-5L and a visual analogue scale (VAS were evaluated. Tobit censored regression models were used to identify predictors of HRQOL in HIV/AIDS patients. Results The mean EQ-5D-5L single index and VAS were 0.65 (95% Confidence Interval (CI = 0.63; 0.67 and 70.3 (95% CI = 69.2; 71.5. Cronbach’s alpha of five dimensions was 0.85. EQ-5D-5L has a good convergent validity with VAS (0.73. It discriminated patients at different HIV/AIDS stages, duration of ART, and CD4 cell count. Predictors of poorer HRQOL included being female, lower education level, unemployment, alcohol and drug use, CD4 Conclusion The EQ-5D-5L has good measurement properties in HIV/AIDS patients and holds potentials for monitoring ART outcomes. Integration of HRQOL measurement using EQ-5D-5L in HIV/AIDS clinical practice could be helpful for economic evaluation of HIV/AIDS interventions.

  18. Association of Immune and Metabolic Receptors C5aR and C5L2 with Adiposity in Women

    Pegah Poursharifi

    2014-01-01

    Full Text Available Adipose tissue receptors C5aR and C5L2 and their heterodimerization/functionality and interaction with ligands C5a and acylation stimulating protein (ASP have been evaluated in cell and rodent studies. Their contribution to obesity factors in humans remains unclear. We hypothesized that C5a receptors, classically required for host defense, are also associated with adiposity. Anthropometry and fasting blood parameters were measured in 136 women divided by body mass index (BMI: normal/overweight (≤30 kg/m2; n = 34, obese I (≤45 kg/m2; n = 33, obese II (≤51 kg/m2; n = 33, and obese III (≤80 kg/m2; n = 36. Subcutaneous and omental adipose tissue C5aR and C5L2 expression were analysed. C5L2 expression was comparable between subcutaneous and omental across all BMI groups. Plasma ASP and ASP/omental C5L2 expression increased with BMI (P < 0.001 and P < 0.01, resp.. While plasma C5a was unchanged, C5aR expression decreased with increasing BMI in subcutaneous and omental tissues (P < 0.01 and P < 0.05, resp., with subcutaneous omental depots. Omental C5L2/C5aR ratio increased with BMI (P < 0.01 with correlations between C5L2/C5aR and waist circumference, HDL-C, and adiponectin. Tissue and BMI differences in receptors and ligands, particularly in omental, suggest relationship to metabolic disturbances and highlight adipose-immune interactions.

  19. 对APISPEC5L/ISO3183超声波探伤对比标样的认识%Cognition of Ultrasonic Testing Reference Specimen in API SPEC 5L/ISO 3183

    甘正红; 任文浩

    2011-01-01

    According to the reflection theory to ultrasonic testing reflection signal of several reference specimens specified in API SPEC 5L/ISO3183, this paper pointed out the respective reflection characteristics, and conducted analysis in conjunction with acceptance criteria. It put forward utilizing reference specimen according to different reflection regulation and equivalent weight to ultrasonic of notches and radial drilling hole (column hole), the both parties of contract should clearly stipulate acceptance reference specimen when adopting API SPEC 5L (44 edition) / ISO3183 standard; The level of sensitivity shall be tested and analyzed combining with the specific condition instead of simply determining result based on differences of artificial reflectors.%依据API SPEC 5L/ISO 3183标准规定的几种超声波探伤对比标样对超声波反射信号的反射理论,指出它们的各自反射特性,结合验收标准进行分析.提出了在使用对比标样时应根据刻槽和径向钻孔(柱孔)对超声波的反射规律不同、当量不同,建议在使用API SPEC 5L(第44版)/ISO3183标准时,合同双方应明确规定验收对比标样;灵敏度的高低不能简单地以人工反射体的差异来判定,要结合具体条件进行测试和分析.

  20. Study of phase transformations In API 5L X80 Steel in order to increase its fracture toughness

    Igor Rafael Vilarouco Pedrosa; Renato Soares de Castro; Yogendra Prasad Yadava; Ricardo Artur Sanguinetti Ferreira

    2013-01-01

    Phase transformations in API 5L X80 steel were studied in different thermomechanical sequences with a view to increasing the fracture toughness of this steel. Dilatometry tests performed on the quenched steel detected a phase transformation occurred, during heating, in the temperature range 593-618 K. This phase transformation was identified as the dissolution of M-A islands. Based on preliminary dilatometric tests, ten thermal and thermomechanical treatments were performed on X80 steel sampl...

  1. A Time Trade-off-derived Value Set of the EQ-5D-5L for Canada

    Pullenayegum, Eleanor; Gaebel, Kathy; Bansback, Nick; Bryan, Stirling; Ohinmaa, Arto; Poissant, Lise; Johnson, Jeffrey A.

    2016-01-01

    Background: The 5-level version of the EQ-5D (EQ-5D-5L) was recently developed. A number of preference-based scoring systems are being developed for several countries around the world. Objective: To develop a value set for the EQ-5D-5L based on societal preferences in Canada. Methods: We used age, sex, and education quota sampling from the general population from 4 cities across Canada. Composite time trade-off (cTTO) and traditional time trade-off (tTTO) were used as the main elicitation technique. A total of 86 EQ-5D-5L health states grouped into 10 blocks were valued using cTTO, whereas a subset of 18 severe states was also valued using tTTO. Participants meeting predefined inconsistency criteria were excluded from the analyses. For the value set development, we used tTTO and positive cTTO values, while censoring negative and zero cTTO values at zero. Models with the main effects presented using linear terms combined with various additional terms were estimated. The preferred model was selected based primarily on logically ordered coefficients, and secondly model fit. Results: Of the 1209 participants who completed the interview, 136 met criteria that excluded them from the primary analyses. The demographics and socioeconomic status of the remaining 1073 participants were similar to the Canadian general population. The preferred model has 5 linear terms for the main effects, a term for level 4 or 5 for each dimension, and a term for the squared total number of level 4 or 5 beyond the first. For this preferred model, the health utilities ranged from −0.148 for the worst (55555) to 0.949 for the best (11111) EQ-5D-5L states. Conclusions: This is the first TTO-based value set of the EQ-5D-5L for Canada. It can be used to support the health utility estimation in economic evaluations for reimbursement decision making in Canada. PMID:26492214

  2. Ford's new 3.5 l V6 gasoline engine. Downsizing with 'EcoBoost'; Der neue 3,5-l-V6-Ottomotor von Ford. Downsizing durch 'EcoBoost'

    Schmidt, Gerhard; Kapp, Daniel; Schamel, Andreas; Hinds, Brett; Weaver, Corey [Ford Motor Company, Dearborn, MI (United States)

    2009-03-15

    Ford banded a new motor technology as 'EcoBoost'. It applies direct fuel injection and turbocharging to gasoline engines and provides a major improvement in fuel economy via engine downsizing, combined with improved performance. The first Ford engine with this technology is the 3.5 l V6 EcoBoost in the 2010 Lincoln MKS luxury sedan. Combustion, fuel, boost, and power conversion systems are discussed in detail with emphasis on the efficiency and value of these systems. Engine level fuel economy and performance are discussed, and compared to conventional gasoline engines. (orig.)

  3. Phytochemical and Biological Studies of <em>Agave em>attenuata>

    Vincenzo De Feo; Muhammad Riaz; Nasir Rasool; Muhammad Zubair; Komal Rizwan; Muhammad Zia-Ul-Haq

    2012-01-01

    The present study was conducted to examine various biological activities of a methanol extract of <em>Agave attenuataem> leaves. GC-MS analysis of the <em>n>-hexane fraction from the extract revealed the presence of 31 compounds, with mono-2-ethylhexyl phthalate (11.37%), 1,2-benzenedicarboxylic acid (6.33%), <em>n>-docosane (6.30%) and eicosane (6.02%) as the major components. The leaves contained appreciable levels of total phenolic contents (10...

  4. Corrosive effect of oil's accompanying water polluted with H2S over steel (API 5L X-52)

    The corrosion from the steel to the carbon in the sale oil pipage conduction, is a serious problem, due to the material and economical looses they cause, damaging even in some cases the productive field. The purpose of this study is to determine the aggressiveness of the oil's water layer, polluted with H2S(g) , over the steel of pipelines' construction (API 5L X-52), taking into account the temperature variations which take place during the transportation of the oil, using the electrochemical techniques of polarisation resistance (LPR) and electrochemical noise. It is pretended to determine the velocity of steel corrosion in the oil's water layer polluted with H2S through electrochemical techniques. It was shown that the temperature increases and the concentration of H2S to 500 ppm in the oil's accompanying water emphasizes the corrosion phenomenon experienced by the steel (9, 188 0 mm/year to 70℃).The results of the electrochemical noise spectrums and the values of the localisation ?s index calculated, shown the presence of corrosion on the steel surface (API 5L X-52).This result was complemented through optic Microscopy which permits to corroborate the poor adherence of the sulphur layers deposited on the metal that increase the appearance of events found with the temperature increase and the concentration of H2S in the environment studied

  5. The new Nissan FF Hybrid + new 4-cylinder 2.5L supercharged engine. A new approach to powersource evolution

    Minakawa, Shunichi; Onoyama, Taiichi; Ishizuka, Takashi [Nissan Motor Co., Ltd., Kanagawa (Japan)

    2013-08-01

    In 2013, Nissan is going to launch a technology combination of 1-Motor 2-Clutch Parallel Hybrid system and 4-cylinder 2.5L supercharged engine for Infiniti QX60 HYBRID and new Nissan Pathfinder HYBRID. This Hybrid system has been developed to have three key advantages: (1) Significant improvement in fuel economy even when Highway driving, (2) Better response and more direct feeling, (3) Lightweight system and low-cost. To achieve these objectives, Nissan fitted a 1-Motor 2-Clutch Parallel system onto a new generation CVT without Torque Converter, combined with downsized 4 cylinder 2.5L supercharged Engine, which provides better fuel economy and V6 3.5-liter class driving performance. Nissan has developed the following proprietary technologies to realize the development of this Hybrid system: - High output and compact Li-ion battery, - Innovative high speed and precise motor and clutch control. Additionally, new technologies are added to both Engine and CVT. Engine: New 4-lobes Roots supercharger with precise electrical boost control. CVT: Chain driven, high efficiency and low friction with wide cover ratio. In this paper Nissan will introduce an outline of the system, key breakthrough technologies and how low fuel economy comparable with the compact car class, has been achieved and demonstrated. (orig.)

  6. Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L across eight patient groups

    Janssen, M F; Pickard, A Simon; Golicki, Dominik;

    2012-01-01

    PURPOSE: The aim of this study was to assess the measurement properties of the 5-level classification system of the EQ-5D (5L), in comparison with the 3-level EQ-5D (3L). METHODS: Participants (n = 3,919) from six countries, including eight patient groups with chronic conditions (cardiovascular...... disease, respiratory disease, depression, diabetes, liver disease, personality disorders, arthritis, and stroke) and a student cohort, completed the 3L and 5L and, for most participants, also dimension-specific rating scales. The 3L and 5L were compared in terms of feasibility (missing values...

  7. Study of phase transformations In API 5L X80 Steel in order to increase its fracture toughness

    Igor Rafael Vilarouco Pedrosa

    2013-04-01

    Full Text Available Phase transformations in API 5L X80 steel were studied in different thermomechanical sequences with a view to increasing the fracture toughness of this steel. Dilatometry tests performed on the quenched steel detected a phase transformation occurred, during heating, in the temperature range 593-618 K. This phase transformation was identified as the dissolution of M-A islands. Based on preliminary dilatometric tests, ten thermal and thermomechanical treatments were performed on X80 steel samples. Initially, the material was hot rolled and quenched and only quenched. On the material without deformation, aging was also performed at temperatures of 603, 673, 723, 773, 823 and 873 K. These treatments resulted in the formation of the acicular ferrite constituent, among others. Tensile tests showed that the aging treatments produced reductions in yield strength and increases in the elongation and toughness of X80 steel. All the treatments resulted in an increase in the tensile strength of steel.

  8. LIVE L4 and LIVE L5L experiments on melt pool and crust behaviour in the RPV lower head

    LIVE-L4 and LIVE-L5L experiments investigated thermal hydraulic behavior of corium pool in the RPV lower head with a 3D test vessel LIVE. The simulant material is 80%-20% KNO3- NaNO3. Transient and steady-state parameters such as melt temperature, heat flux distribution through the vessel wall as well as crust formation characteristics were obtained. The two tests demonstrated that transient events like melt relocation and change of decay power facilitate crust deformation and change of crust thickness. The dimensionless melt temperature and heat flux through wall during the steady state can be well described independent of power density. However the dimensionless melt temperature and heat flux are dependent on the pool height. A low pool has stronger focusing effect at the upper surface than in a high pool. (author)

  9. Cross-cultural measurement equivalence of the 5-level EQ-5D (EQ-5D-5L) in patients with type 2 diabetes mellitus in Singapore

    Wang, Ye; Tan, Ngiap-Chuan; Tay, Ee-Guan; Thumboo, Julian; Luo, Nan

    2015-01-01

    Background: This study aimed to assess the measurement equivalence of the 5-level EQ-5D (EQ-5D-5L) among the English, Chinese, and Malay versions. Methods: A convenience sample of patients with type 2 diabetes mellitus were enrolled from a public primary health care institution in Singapore. The survey questionnaire comprised the EQ-5D-5L and questions assessing participants’ socio-demographic and clinical characteristics. Multiple linear regression models were used to assess the difference i...

  10. Comportamiento de Laminaciones Coplanares y No Coplanares en Acero API5L X52 Simuladas mediante Elementos Finitos Behavior of Coplanar and Non-Coplanar Laminations in API5L X52 Steel Simulated by Finite Elements

    Alberto Servin

    2009-01-01

    Full Text Available Se determina el comportamiento mecánico de laminaciones simples y escalonadas modeladas por elementos finitos en condiciones no lineales de esfuerzo-deformación, para comprender la secuencia de la interacción de los campos de esfuerzos en los extremos de la grietas. Se estableció una matriz de simulación variando la extensión circunferencial de las laminaciones, con espesor del tubo de 610mm de diámetro, con separación vertical y horizontal para el caso de laminaciones escalonadas. Se determino la función de distribución de esfuerzos en la región de las laminaciones en función de la presión en la grieta y en el tubo. Se estableció la presión que origina alcanzar la cedencia y resistencia ultima del material API5L X52, determinando que las laminaciones simples cuya extensión circunferencial va de 24 a 127 mm, soportan 50% más de presión de cedencia que las laminaciones escalonadas, y el 100% más de presión máxima permisible. Basados en la graficas presión versus radio de las laminaciones se concluye que las laminaciones no coplanares representan mayor riesgo de agrietamiento en una tubería.The mechanical behavior of the coplanar and non coplanar laminations by finite element using non lineal material conditions was determined, with the purpose of knowing the interaction sequence of the stress fields in the crack tips. The analysis includes a matrix simulation considering the circumferential length lamination, wall thickness of the pipe 610mm diameter, with vertical and horizontal distance for non coplanar laminations. The stress distribution in the laminations regions as a function of the internal pressures in the cracks and pipe were determined. The simulations done allowed defining the yield and the strength pressure that reach the mechanical properties of the API 5L X52. It was found that coplanar laminations with 24 at 127mm of circumferential length resist 50% more yield pressure than the non coplanar laminations and

  11. KAYNAKLI API 5L X65 BORU HATTI ÇELİKLERİNİN KlRlLMA TOKLUGU

    HÜSEYİN UZUN

    2002-06-01

    Full Text Available Petrol ve dogal gaz boru hatla rında ya ygın olarak kulla nıla n ve ta ndem tozaltı ka yna k metodu ile bir leşt irilen API 5L X65 d u al fa zlı çeliğin kırılma to lduğu tespit edilmiştir. Kırılma to lduğu, çentikli üç nokta kırılma tokluğu deneyi kulla nıla ra k belirlenmiştir. Çentik, hem kayna k dikişinin or tası na hem de ısının tesiri altında ki bölgesi (IT AB içerisinin içine gelecek şekilde aç ılarak deney uygula nmıştır. Her bir nurnuneye gerilim giderme ta vlaması uygul anarak, kırılma tokluğu değerler inin nasıl etkilendiği değerlendirilmiştir. Elde edilen sonuçlara göre, gerilim giderme ta vı uygula nmamış ve uygulanmış numunelerde, kaynak dikişin in kırılma to ld u ğ u , IT AB bölgesinin kırılma to lduğundan daha yüksek çıkmıştır. Anahtar Kelimeler - API 5L X65 çeliğinin kırılma tokluğu, spira l dikişli borular, ta ndem tozaltı kaynağı. Abstract -The fra cture toughness of API 5L X65 dual­phase steel welded by ta ndem submerged are welding process, which is used widely petrolenın and na tural gas pipelines, wa s investigated. The fra cture toughness values were obta ined using by three point bend fracture toughness test specimens. The notch was machined either in the center of w el d meta l or the heat affected zone (H AZ. It wa s employed stress relief annealing in order to inves tigate the effect heat treatment on the fra cture toughness va lues. The results show tha t the fracture toughness va lues of weld metal with both heat treatment and non-h eat treatment are higher than that of the heat affected zone. Keywords - Fracture toughness of API 5L X65 steel, sp ira ll y welded pipeline, tandem submerged are welding. ı. GİRİŞ Doğal gaz ve petrol taşıma borularında, sistemin emniyeti için API 5L standardına uygun sertifikalı borular tercih edilmektedir. Bu standarda göre, boyuna veya H. UZUN: Sakarya Üniversitesi, Teknik Eğitim Fak

  12. API RP 5 L3-2014输送钢管落锤撕裂试验推荐做法简介%Introduction of Drop-Weight Tear Tests on Line Pipe Recommended Practice API RP 5 L3-2014

    孙宏

    2016-01-01

    介绍了新版的落锤撕裂试验(DWTT)的试验标准API RP 5L3-2014《输送钢管落锤撕裂试验推荐做法》,并与以前的版本API RP 5L3-1996进行了比较。对比发现新版的API RP 5L3-2014《输送钢管落锤撕裂试验推荐做法》仍然延续了API RP 5L3-1996的主要技术内容,并与国内的常用的SY/T 6476-2013和GB/T8363-2007仍然有一定差异。%The latest edition of Drop-Weight Tear Tests on Line Pipe Recommended Practice API RP 5L3-2014 was introduced compared with the last edition API RP 5L3-1996. It is found that the latest edition of API RP 5L3 still continues containing more technical content in the API RP 5L3-1996, but it is apparently different with SY/T 6476-2013 and GB/T 8363-2007, which are mainly used domestically.

  13. KAYNAKLI API 5L X65 BORU HATTI ÇELİKLERİNİN KlRlLMA TOKLUGU

    HÜSEYİN UZUN

    2002-01-01

    Petrol ve dogal gaz boru hatla rında ya ygın olarak kulla nıla n ve ta ndem tozaltı ka yna k metodu ile bir leşt irilen API 5L X65 d u al fa zlı çeliğin kırılma to lduğu tespit edilmiştir. Kırılma to lduğu, çentikli üç nokta kırılma tokluğu deneyi kulla nıla ra k belirlenmiştir. Çentik, hem kayna k dikişinin or tası na hem de ısının tesiri altında ki bölgesi (IT AB) içerisinin içine gelecek şekilde aç ılarak deney uygula nmıştır. Her bir nurnuneye gerilim giderme ta vlaması uygul anarak, kırı...

  14. Studi Laju Korosi dan Surface Morfologi Pipa Bawah Laut API 5L Grade X65 dengan Variasi Sudut Bending

    Apri Malani Putri

    2012-09-01

    Full Text Available Proses bending banyak digunakan dalam proses produksi pada pipa. Proses ini akan menghasilkan peristiwa tensile dan compress, maka stress yang terjadi akibat gaya tekan atau gaya tarik ini akan bekerja simultan pada lingkungan korosif yang dapat menyebabkan terjadinya korosi. Deformasi yang terjadi ini akan mengakibatkan perbedaan tingkat laju korosi pada setiap perubahannya, yaitu dengan sudut bending yang berbeda. Oleh karena itu, untuk membuktikannya dilakukanlah penelitian dengan tiga sudut bending yang berbeda yaitu 60°, 90°, dan 135°. Material yang digunakan adalah pipa bawah laut API 5L Grade X65. Pipa ini dibending dengan sudut di atas, kemudian dipotong tiga spesimen pada setiap intrados dan ektsrados pipa untuk setiap sudut bending. Pengujian laju korosi dengan menggunakan sel tiga elektroda dengan campuran larutan FeCl3 dan 0,3% aquades. Dari hasil penelitian diperoleh nilai laju korosi untuk intrados bending pipa ; sudut bending 60° adalah 0,75 mm/year, sudut 90° adalah 0,64 mm/year, dan untuk sudut 135° adalah 0,43 mm/year. Sedangkan untuk ekstrados pipa; sudut 60° nilai laju korosinya adalah 0,59 mm/year, sudut 90° adalah 0,49 mm/year, dan untuk sudut bending 135° nilai laju korosinya adalah 0,4 mm/year. Analisa surface morfologi yang dilakukan pada spesimen menyimpulkan bahwa semakin tinggi nilai laju korosi, maka bentuk permukaan dari spesimen akan semakin kasar,begitupun sebaliknya

  15. Reference Gene Selection in the Desert Plant <em>Eremosparton songoricuem>m>

    Dao-Yuan Zhang

    2012-06-01

    Full Text Available <em>Eremosparton songoricum em>(Litv. Vass. (<em>E. songoricumem> is a rare and extremely drought-tolerant desert plant that holds promise as a model organism for the identification of genes associated with water deficit stress. Here, we cloned and evaluated the expression of eight candidate reference genes using quantitative real-time reverse transcriptase polymerase chain reactions. The expression of these candidate reference genes was analyzed in a diverse set of 20 samples including various <em>E. songoricumem> plant tissues exposed to multiple environmental stresses. GeNorm analysis indicated that expression stability varied between the reference genes in the different experimental conditions, but the two most stable reference genes were sufficient for normalization in most conditions.<em> EsEFem> and <em>Esα-TUB> were sufficient for various stress conditions, <em>EsEF> and <em>EsACT> were suitable for samples of differing germination stages, and <em>EsGAPDH>and <em>Es>UBQ em>were most stable across multiple adult tissue samples. The <em>Es18Sem> gene was unsuitable as a reference gene in our analysis. In addition, the expression level of the drought-stress related transcription factor <em>EsDREB2em>> em>verified the utility of<em> E. songoricumem> reference genes and indicated that no single gene was adequate for normalization on its own. This is the first systematic report on the selection of reference genes in <em>E. songoricumem>, and these data will facilitate future work on gene expression in this species.

  16. Synthesis, Crystal Structure and Luminescent Property of Cd (II Complex with <em>N-Benzenesulphonyl-L>-leucine

    Xishi Tai

    2012-09-01

    Full Text Available A new trinuclear Cd (II complex [Cd3(L6(2,2-bipyridine3] [L =<em> Nem>-phenylsulfonyl-L>-leucinato] has been synthesized and characterized by elemental analysis, IR and X-ray single crystal diffraction analysis. The results show that the complex belongs to the orthorhombic, space group<em> Pem>212121 with<em> aem> = 16.877(3 Å, <em>b> em>= 22.875(5 Å, <em>c em>= 29.495(6 Å, <em>α> em>= <emem>= <emem>= 90°, <em>V> em>= 11387(4 Å3, <em>Z> em>= 4, <em>Dc>= 1.416 μg·m−3, <emem>= 0.737 mm−1, <em>F> em>(000 = 4992, and final <em>R>1 = 0.0390, <em>ωR>2 = 0.0989. The complex comprises two seven-coordinated Cd (II atoms, with a N2O5 distorted pengonal bipyramidal coordination environment and a six-coordinated Cd (II atom, with a N2O4 distorted octahedral coordination environment. The molecules form one dimensional chain structure by the interaction of bridged carboxylato groups, hydrogen bonds and p-p interaction of 2,2-bipyridine. The luminescent properties of the Cd (II complex and <em>N-Benzenesulphonyl-L>-leucine in solid and in CH3OH solution also have been investigated.

  17. Synthesis and Cytotoxic Activity of Some Novel <em>N>-Pyridinyl-2-(6-phenylimidazo[2,1-<em>b>]thiazol-3-ylacetamide Derivatives

    Huaiwei Ding

    2012-04-01

    Full Text Available A series of novel compounds bearing imidazo[2,1-<em>b>]thiazole scaffolds were designed and synthesized based on the optimization of the virtual screening hit compound <em>N>-(6-morpholinopyridin-3-yl-2-(6-phenylimidazo[2,1-b]thiazol-3-ylacetamide (5a, and tested for their cytotoxicity against human cancer cell lines, including HepG2 and MDA-MB-231. The results indicated that the compound 2-(6-(4-chlorophenylimidazo[2,1-b]thiazol-3-yl-N-(6-(4-(4-methoxybenzylpiperazin-1-ylpyridin-3-ylacetamide (5l, with slightly higher inhibition on VEGFR2 than 5a (5.72% and 3.76% inhibitory rate at 20 μM, respectively, was a potential inhibitor against MDA-MB-231 (IC50 = 1.4 μM compared with sorafenib (IC50 = 5.2 μM, and showed more selectivity against MDA-MB-231 than HepG2 cell line (IC50 = 22.6 μM.

  18. Estudio del daño por hidrógeno en uniones soldadas de un acero API 5L X52

    Réquiz, R.; Camero, S.; Aristizabal, V.; A. Rivas

    2008-01-01

    The main objective of the present investigation was to study the susceptibility to hydrogen damage on a type API 5L X52 steel welded by electrical resistance. Several techniques, such as hydrogen permeation and cathodic charging were used. The metallic material was characterized using SEM and TEM. The base metal microstructure was very similar to that one corresponding to the welded area. This microstructure was mainly comprised by ferrite and perlite, differing only in the grain size. Theref...

  19. Analisa Pengaruh Jenis Elektroda terhadap Laju Korosi pada Pengelasan Pipa API 5L Grade X65 dengan Media Korosi FeCl3

    Gita Anggaretno; Imam Rochani; Heri Supomo

    2012-01-01

    Submarine pipelines (pipa bawah laut) di desain untuk transportasi minyak, gas atau air dari lepas pantai menuju receiving point. Baja API 5L Grade X65 merupakan jenis pipa baja yang banyak digunakan pada pipa penyalur gas, air, dan minyak pada pipa bawah laut. Sistem perpipaan ini tidak mungkin terbentuk tanpa adanya proses las. Pengelasan Flux Cored Arc Welding (FCAW)  merupakan las yang umum digunakan dalam struktur anjungan lepas pantai. Penelitian ini bertujuan untuk mengetahui pengaruh ...

  20. Evaluation of Antioxidant and Antiproliferative Properties of Three <em>Actinidia> (<em>Actinidia> <em>kolomikta>, <em>Actinidia argutaem>, <em>Actinidia> <em>chinensis> Extracts <em>in Vitroem>

    Jia-Ren Liu

    2012-05-01

    Full Text Available The total phenolic content, total flavonoid content, vitamin C content, and antioxidant activities of ethanol extracts from different kiwifruit varieties (<em>Actinidia> <em>kolomikta>, <em>Actinidia argutaem>, <em>Actinidia> <em>chinensis> were determined in this study. Multiple scavenging activity assays including the hydroxyl radical, O2·radical, DPPH, and the ABTS+ radical scavenging activity assays were used to identify the antioxidant activities of <em>Actinidia> extracts. The cell viability of HepG2 and HT-29 cells was also examined in this study. The results demonstrated that the <em>Actinidia kolomiktaem> extract had a higher antioxidant activity than the other two <em>Actinidia> extracts. There is a positive correlation between antioxidant activity and the polyphenols and vitamin C content in all three extracts (<em>R>2 ≥ 0.712, <em>p> em>< 0.05. The <em>Actinidia argutaem> extract had the highest inhibitory effect on HepG2 and HT-29 cell growth. These results provide new insight into the health functions of fruit and demonstrate that <em>Actinidia> extracts can potentially have health benefits.

  1. <em>α>-Glucosidase Inhibitory Constituents from <em>Acanthopanax senticosusem> Harm Leaves

    Hai-Xue Kuang

    2012-05-01

    Full Text Available A new triterpene glycoside, 3-<em>O-[(α>-L-rhamnopyranosyl(1→2]-[<em>β>-D-glucuronopyranosyl-6-<em>O>-methyl ester]-olean-12-ene-28-olic acid (1 and a new indole alkaloid, 5-methoxy-2-oxoindolin-3-acetic acid methyl ester (5 were isolated from the leaves of <em>Acanthopanax senticosusem> Harms along with six known compounds. The structures of the new compounds were determined by means of 2D-NMR experiments and chemical methods. All the isolated compounds were evaluated for their glycosidase inhibition activities and compound 6 showed significant <em>α>-glucosidase inhibition activity.

  2. Structural and electrical conductivity studies on the solid electrolyte system {sub x}Li2O-(100-x) [0.5B{sub 2}O{sub 3}-0.5 P{sub 2}O{sub 5}] where 20<x<70

    Padmasree, K. P.; Diaz-Guillen, M. R.; Diaz-Guillen, J. A.; Mendoza, E. M.; Fuentes, A. F. [Cinvestav, unidad Saltillo, Ramos Arizpe, Coahuila (Mexico)]. E-mail: padma512@yahoo.com

    2009-09-15

    Lithium ion conducting glasses have been extensively investigated due to their potential application as solid state amorphous electrolytes in lithium rechargeable batteries. The use of glassy electrolytes in all solid state devices may provide numerous advantages like increased safety, facility of fabrication and miniaturization and having a higher conductivity than those of the crystalline counterparts. In this work, we prepared and studied the Lithium ion conducting glassy solid electrolytes of the composition {sub x}Li{sub 2}O-(1-x)[0.5B{sub 2}O{sub 3} -0.5P{sub 2}O{sub 5}] where 20<x<70, by melt quenching technique. The obtained solid material is characterized through X-ray diffraction (XRD), Differential thermal analysis (DTA), and Fourier transform infra-red spectrometry (FTIR) and impedance spectroscopy techniques. The conductivity obtained is of the order of 10-7S/cm at room temperature and IR spectra reveal that the glass matrix undergoes structural modification with the addition of the glass modifier Li{sub 2}O. [Spanish] Los vidrios conductores de ion litio se han investigado ampliamente por su aplicacion potencial como electrolitos amorfos de estado solido en baterias recargables de litio. El uso de electrolitos vitreos en todos los dispositivos de estado solido puede proporcionar numerosas ventajas como mayor seguridad, facilidad de fabricacion y miniaturizacion, asi como tener una conductividad mas alta que la de sus contrapartes cristalinas. En este trabajo, se prepararon y estudiaron los electrolitos solidos vitreos conductores de ion litio de la composicion {sub x}Li2O-(1-x)[0.5B{sub 2}O{sub 3} -0.5P{sub 2}O{sub 5}] donde 20<x<70, por medio de la tecnica de templado. El material solido obtenido se caracteriza mediante difraccion de rayos X (DRX), analisis termico diferencial (ATD) y espectrometria infrarroja de la transformada de Fourier (EITF) y tecnicas de espectroscopia por impedancia. La conductividad obtenida es del orden de 10-7S/cm a

  3. Three New Myrsinol Diterpenes from <em>Euphorbia proliferaem> and Their Neuroprotective Activities

    Yuanqiang Guo

    2012-08-01

    Full Text Available Three new myrsinol diterpenes were isolated from the roots of<em> em>>Euphorbia proliferaem>. Their structures were elucidated as 2<em>α-O>-isobutyryl-3<em>β>,5<em>α>,7<em>β>,10,15<em>β-penta-O>-acetyl-14<em>α-O>-benzoyl-10,18-dihydromyrsinol (1, 2<em>α-O>-isobutyryl-3<em>β-O>-propion-yl-5<em>α>,7<em>β>,10,15<em>β-tetra-O>-acetyl-10,18-dihydromyrsinol (2, and 2<em>α>,14<em>α-di-O>-benzoyl-3<em>β>,5<em>α>,7<em>β>,10,15<em>β-penta-O>-acetyl-10,18-dihydromyrsinol (3 on the basis of spectroscopic data analyses (IR, ESI-MS, HR-ESI-MS, and 1D and 2D NMR. Their neuroprotective activities were evaluated and compounds 1 and 2 showed neuroprotective effects against MPP+-induced neuronal cell death in SH-SY5Y cells.

  4. The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

    Vella Adrian

    2007-11-01

    Full Text Available Abstract Background As genes associated with immune-mediated diseases have an increased prior probability of being associated with other immune-mediated diseases, we tested three such genes, IL23R, IRF5 and CD40, for an association with type 1 diabetes. In addition, we tested seven genes, TAF5L, PDCD1, TCF7, IL12B, IL6, ICAM1 and TBX21, with published marginal or inconsistent evidence of an association with type 1 diabetes. Methods We genotyped reported polymorphisms of the ten genes, nonsynonymous SNPs (nsSNPs and, for the IL12B and IL6 regions, tag SNPs in up to 7,888 case, 8,858 control and 3,142 parent-child trio samples. In addition, we analysed data from the Wellcome Trust Case Control Consortium genome-wide association study to determine whether there was any further evidence of an association in each gene region. Results We found some evidence of associations between type 1 diabetes and TAF5L, PDCD1, TCF7 and IL6 (ORs = 1.05 – 1.13; P = 0.0291 – 4.16 × 10-4. No evidence of an association was obtained for IL12B, IRF5, IL23R, ICAM1, TBX21 and CD40, although there was some evidence of an association (OR = 1.10; P = 0.0257 from the genome-wide association study for the ICAM1 region. Conclusion We failed to exclude the possibility of some effect in type 1 diabetes for TAF5L, PDCD1, TCF7, IL6 and ICAM1. Additional studies, of these and other candidate genes, employing much larger sample sizes and analysis of additional polymorphisms in each gene and its flanking region will be required to ascertain their contributions to type 1 diabetes susceptibility.

  5. The Effect of Temperature and Acid Gas Loading on Corrosion Behavior of API 5L X52 Carbon Steel in Amine Unit

    Javidi, M.; Lalehparvar, M. M.; Ghassemi, A.

    2016-05-01

    The effect of temperature and H2S concentration on amine corrosion of API 5L X52 carbon steel in a CO2-saturated 25 wt.% diethanolamine solution was investigated via electrochemical techniques. It was found that increase in temperature from 25 to 80 °C resulted in severe increase in corrosion rate from 0.88 to 16.24 mpy due to increase in degradation rate of amine. Also, it was concluded that increase in H2S concentration led to increase in corrosion rate because of formation of more heat stable amine salts. The effect of temperature on corrosion rate was more significant than acid gas loading.

  6. Corrosion Study of Steel API 5A, 5L and AISI 1080, 1020 in Drill-Mud Environment of Iranian Hydrocarbon Fields

    Farzam, M.; Baghery, P.; Mardan Dezfully, H. R.

    2011-01-01

    API 5A and 5L (grades J55, H40, N80, and K55) are used in making drill pipe and well casing. In this paper after studying the rheological and chemical properties of the mud, the effective corrosion parameters were reviewed and studied. The drill pipe corrosion management, with reference to NACE PRO 502-2002 was made and showed that for 50 drilling rigs 120 million dollars is to be spent in 21 years for corrosion damage. Potentiodynamic polarization tests were made to study the drill-pipe (API...

  7. Influencia del precalentamiento en las propiedades de uniones soldadas de acero API 5L-X80 soldadas con alambre tubular autoprotegido

    Cooper, R.; Silva, J. H.F.; Trevisan, R. E.

    2004-01-01

    The present work refers to the characterization of API 5L-X80 pipeline joints welded with self-shielded flux cored wire. This process was evaluated under preheating conditions, with an uniform and steady heat input. All joints were welded in flat position (IG), with the pipe turning and the torch still. Tube dimensions were 762 mm in external diameter and 16 mm in thickness. Welds were applied on single V-groove, with six weld beads, along with three levels of preheating temperatures (room te...

  8. Neonatal Phosphate Nutrition Alters <em>in em>Vivo> and <em>in em>Vitro> Satellite Cell Activity in Pigs

    Chad H. Stahl

    2012-05-01

    Full Text Available Satellite cell activity is necessary for postnatal skeletal muscle growth. Severe phosphate (PO4 deficiency can alter satellite cell activity, however the role of neonatal PO4 nutrition on satellite cell biology remains obscure. Twenty-one piglets (1 day of age, 1.8 ± 0.2 kg BW were pair-fed liquid diets that were either PO4 adequate (0.9% total P, supra-adequate (1.2% total P in PO4 requirement or deficient (0.7% total P in PO4 content for 12 days. Body weight was recorded daily and blood samples collected every 6 days. At day 12, pigs were orally dosed with BrdU and 12 h later, satellite cells were isolated. Satellite cells were also cultured <em>in vitroem> for 7 days to determine if PO4 nutrition alters their ability to proceed through their myogenic lineage. Dietary PO4 deficiency resulted in reduced (<em>P> < 0.05 sera PO4 and parathyroid hormone (PTH concentrations, while supra-adequate dietary PO4 improved (<em>P> < 0.05 feed conversion efficiency as compared to the PO4 adequate group. <em>In vivoem> satellite cell proliferation was reduced (<em>P> < 0.05 among the PO4 deficient pigs, and these cells had altered <em>in vitroem> expression of markers of myogenic progression. Further work to better understand early nutritional programming of satellite cells and the potential benefits of emphasizing early PO4 nutrition for future lean growth potential is warranted.

  9. Analisa Pengaruh Jenis Elektroda terhadap Laju Korosi pada Pengelasan Pipa API 5L Grade X65 dengan Media Korosi FeCl3

    Gita Anggaretno

    2012-09-01

    Full Text Available Submarine pipelines (pipa bawah laut di desain untuk transportasi minyak, gas atau air dari lepas pantai menuju receiving point. Baja API 5L Grade X65 merupakan jenis pipa baja yang banyak digunakan pada pipa penyalur gas, air, dan minyak pada pipa bawah laut. Sistem perpipaan ini tidak mungkin terbentuk tanpa adanya proses las. Pengelasan Flux Cored Arc Welding (FCAW  merupakan las yang umum digunakan dalam struktur anjungan lepas pantai. Penelitian ini bertujuan untuk mengetahui pengaruh dari variasi elektroda pengelasan terhadap laju korosi pada pipa API 5L Grade X65. Variasi elektroda yang digunakan adalah elektroda spesifikasi AWS yaitu E7018, E6010 dan E6013. Metode pengujian korosi ini menggunakan bantuan sel tiga elektroda dengan media korosi FeCl3 yang mengacu pada ASTM G48. Dari pengujian ini didapatkan hasil laju korosi pada pengelasan pipa dengan elektroda E7018 adalah 0,53 mmpy, untuk elektroda E6013 adalah 0,69 mmpy, dan untuk E6010 adalah 0,62 mmpy. Perbedaan laju korosi tersebut dipengaruhi oleh tensile strength pada elektroda dan baja yang di las. Selisih kandungan unsur Mangan (Mn pada pipa dan elektroda las juga mempengaruhi perbedaan laju korosi pada pipa. Berdasarkan hasil foto SEM (Scanning Electron Microscope, secara morfologi permukaan weldmetal dengan nilai laju korosi paling tinggi, permukaanya terlihat lebih kasar. Akan tetapi laju korosi hasil las dengan elektroda-elektroda trsebut masih berada pada level yang diijinkan.

  10. Influencia del precalentamiento en las propiedades de uniones soldadas de acero API 5L-X80 soldadas con alambre tubular autoprotegido

    Cooper, R.

    2004-08-01

    Full Text Available The present work refers to the characterization of API 5L-X80 pipeline joints welded with self-shielded flux cored wire. This process was evaluated under preheating conditions, with an uniform and steady heat input. All joints were welded in flat position (IG, with the pipe turning and the torch still. Tube dimensions were 762 mm in external diameter and 16 mm in thickness. Welds were applied on single V-groove, with six weld beads, along with three levels of preheating temperatures (room temperature, 100 °C, 160 °C. These temperatures were maintained as interpass temperature. The filler metal E71T8-K6 with mechanical properties different from parent metal was used in undermatched conditions. The weld characterization is presented according to the mechanical test results of tensile strength, hardness and impact test. The mechanical tests were conducted according to API 1104, AWS and ASTM standards. API 1104 and API 51 were used as screening criteria. According to the results obtained, it was possible to remark that it is appropriate to weld API 5L-X80 steel ducts with Self-shielded Flux Cored wires, in conformance to the API standards and no preheat temperature is necessary.

    Este trabajo presenta un estudio sobre la caracterización de las propiedades mecánicas de uniones soldadas con alambre tubular autoprotegido, de acero API 5L-X80. En este sentido, se evalúa la influencia de la temperatura de precalentamiento, manteniendo el aporte de calor uniforme. Todas las uniones soldadas se realizaron en la posición plana (IG, con la antorcha fíja y la tubería girando. Se utilizó un tubo de 762 mm de diámetro exterior y 16 mm de espesor. Las soldaduras se aplicaron sobre una unión de tope con bisel en V simple, utilizando 6 pasadas, con tres niveles de temperatura de precalentamiento (ambiente, 100 °C y 160 °C. Estas temperaturas se mantuvieron como temperatura entre pasadas. El metal de aporte, del tipo E71T8-K6, se utilizó en la

  11. Constituents from <em>Vigna em>vexillata> and Their Anti-Inflammatory Activity

    Guo-Feng Chen

    2012-08-01

    Full Text Available The seeds of <em>Vigna em>genus are important food resources and there have already been many reports regarding their bioactivities. In our preliminary bioassay, the chloroform layer of methanol extracts of<em> V. vexillata em>demonstrated significant anti-inflammatory bioactivity. Therefore, the present research is aimed to purify and identify the anti-inflammatory principles of <em>V. vexillataem>. One new sterol (1 and two new isoflavones (2,3 were reported from the natural sources for the first time and their chemical structures were determined by the spectroscopic and mass spectrometric analyses. In addition, 37 known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. Among the isolates, daidzein (23, abscisic acid (25, and quercetin (40 displayed the most significant inhibition of superoxide anion generation and elastase release.

  12. The Antimicrobial Efficacy of <em>Elaeis guineensisem>: Characterization, <em>in Vitroem> and <em>in Vivoem> Studies

    Sreenivasan Sasidharan

    2012-04-01

    Full Text Available The urgent need to treat multi-drug resistant pathogenic microorganisms in chronically infected patients has given rise to the development of new antimicrobials from natural resources. We have tested <em>Elaeis guineensis em>Jacq> em>(Arecaceae methanol extract against a variety of bacterial, fungal and yeast strains associated with infections. Our studies have demonstrated that <em>E. guineensisem> exhibits excellent antimicrobial activity <em>in vitroem> and <em>in vivoem> against the bacterial and fungal strains tested. A marked inhibitory effect of the <em>E. guineensisem> extracts was observed against <em>C. albicansem> whereby <em>E. guineensisem> extract at ½, 1, or 2 times the MIC significantly inhibited <em>C. albicansem> growth with a noticeable drop in optical density (OD of the bacterial culture. This finding confirmed the anticandidal activity of the extract on <em>C. albicansem>. Imaging using scanning (SEM and transmission (TEM electron microscopy was done to determine the major alterations in the microstructure of the extract-treated <em>C. albicansem>. The main abnormalities noted via SEM and TEM studies were the alteration in morphology of the yeast cells. <em>In vivoem> antimicrobial activity was studies in mice that had been inoculated with <em>C. albicansem> and exhibited good anticandidal activity. The authors conclude that the extract may be used as a candidate for the development of anticandidal agent.<em> em>

  13. Evaluation of Pseudopteroxazole and Pseudopterosin Derivatives against <em>Mycobacterium> <em>tuberculosis> and Other Pathogens

    Malcolm W. B. McCulloch

    2012-08-01

    Full Text Available Pseudopterosins and pseudopteroxazole are intriguing marine natural products that possess notable antimicrobial activity with a commensurate lack of cytotoxicity. New semi-synthetic pseudopteroxazoles, pseudopteroquinoxalines and pseudopterosin congeners along with simple synthetic mimics of the terpene skeleton were synthesized. In order to build structure-activity relationships, a set of 29 new and previously reported compounds was assessed for <em>in> <em>vitro> antimicrobial and cytotoxic activities. A number of congeners exhibited antimicrobial activity against a range of Gram-positive bacteria including <em>Mycobacterium> <em>tuberculosis> H37Rv, with four displaying notable antitubercular activity against both replicating and non-replicating persistent forms of <em>M.> <em>tuberculosis>. One new semi-synthetic compound, 21-((1<em>H>-imidazol-5-ylmethyl-pseudopteroxazole (7a, was more potent than the natural products pseudopterosin and pseudopteroxazole and exhibited equipotent activity against both replicating and non-replicating persistent forms of <em>M.> <em>tuberculosis> with a near absence of <em>in> <em>vitro> cytotoxicity. Pseudopteroxazole also exhibited activity against strains of <em>M.> <em>tuberculosis> H37Rv resistant to six clinically used antibiotics.

  14. Efficient Heterologous Transformation of <em>Chlamydomonas> reinhardtiiem> <em>npq2em> Mutant with the Zeaxanthin Epoxidase Gene Isolated and Characterized from<em> Chlorella zofingiensisem>

    Herminia Rodríguez

    2012-09-01

    Full Text Available In the violaxanthin cycle, the violaxanthin de-epoxidase and zeaxanthin epoxidase catalyze the inter-conversion between violaxanthin and zeaxanthin in both plants and green algae. The zeaxanthin epoxidase gene from the green microalga <em>Chlorella zofingiensisem> (<em>Czzep> has been isolated<em>. em>This gene encodes a polypeptide of 596 amino acids. A single copy of <em>Czzep> has been found in the <em>C. zofingiensisem> genome by Southern blot analysis. qPCR analysis has shown that transcript levels of <em>Czzep> were increased after zeaxanthin formation under high light conditions. The functionality of <em>Czzep> gene by heterologous genetic complementation in the <em>Chlamydomonas> mutant <em>npq2em>, which lacks zeaxanthin epoxidase (ZEP activity and accumulates zeaxanthin in all conditions, was analyzed. The <em>Czzep> gene was adequately inserted in the pSI105 vector and expressed in <em>npq2em>. The positive transformants were able to efficiently convert zeaxanthin into violaxanthin, as well as to restore their maximum quantum efficiency of the PSII (Fv/Fm. These results show that <em>Chlamydomonas> can be an efficient tool for heterologous expression and metabolic engineering for biotechnological applications.

  15. Mechanism of thermal ring closure of M(CO) sub 5 L (L = bidentate ligand) produced during photolysis of group 6 hexacarbonyl complexes

    Reddy, K.B.; van Eldik, R. (Univ. of Witten/Herdecke (West Germany))

    1990-05-01

    The kinetics of the thermal ring-closure reactions of M(CO){sub 5}L, produced during the photolysis of M(CO){sub 6}/L for L = ethylenediamine (en) and 1,4-diisopropyl-1,4-diazabutadiene (dab), were studied as a function of (L), temperature, and pressure. The values of {Delta}S{double dagger} and {Delta}V{double dagger} are significantly negative, {minus}40 to {minus}170 J K{sup {minus}1} mol{sup {minus}1} and {minus}5.4 to {minus}13.7 cm{sup 3} mol{sup {minus}1}, respectively, for M = Cr (L = en) and M = Mo, W (L = en, dab) and support an associative ring-closure mechanism. The results demonstrate the crucial role played by the size of the metal center and the steric hindrance on L.

  16. Isolation and characterization of P1 minireplicons, lambda-P1:5R and lambda-P1:5L.

    Sternberg, N; Austin, S

    1983-01-01

    We have isolated two new classes of P1 miniplasmids, called lambda-P1:5R and lambda-P1:5L, by the in vivo extension of a cloned P1 fragment, EcoRI-5, which by itself is not capable of plasmid replication. The lambda-P1:5R plasmids contain EcoRI-5 plus a variable portion of the adjacent P1 EcoRI fragment 8. They have a copy number like that of P1 (about 1 per host chromosome), are faithfully segregated at cell division, and are subject to incompatibility exerted by either a single copy of P1 o...

  17. Overview of pressure-drawdown production-test results for the JAPEX/JNOC/GSC et al. Mallik 5L-38 gas hydrate production research well

    Hancock, S.H.; Carle, D.; Weatherill, B. [APA Petroleum Engineering Ltd., Calgary, AB (Canada); Dallimore, S.R. [Geological Survey of Canada, Pacific Geoscience Centre, Sidney, BC (Canada); Collett, T.S. [United States Geological Survey, Denver, CO (United States); Satoh, T. [Japan Petroleum Exploration Co. Ltd., Tokyo (Japan); Inoue, T. [Japan National Oil Corp., Chiba (Japan)

    2005-07-01

    Schlumberger's Modular Dynamic Tester (MDT) cased hole wireline tool was used during a pressure drawdown production test at the Mallik 5L-38 well to successfully test separate hydrate intervals as well as free gas and water zones. This paper provided an overview of the pressure-drawdown testing operations and results. Preliminary analysis of the gas hydrate porous-media response was also presented. Two important phenomena were observed during the hydrate tests: (1) free gas was produced on a steady state basis following the initial clean-up flow of water, and (2) the pressure response upon shut-in displayed porous media effects and indicated both flow contribution and pressure effects beyond the surface area of the hydrate open to the wellbore. Since analytical pressure transient analysis software cannot incorporate dynamic reservoir parameters, conventional analytical techniques were used to evaluate the test data.

  18. High spin, hole delocalization and electron transfer in LBaCo2O5.5 (L = Sm, Eu, Gd, Tb, Dy, Y)

    By means of electron-correlation-corrected density functional calculations for GdBaCoO5.5, it has been found that the pdσ hole delocalization in the 'almost high-spin' state is responsible for the antiferromagnetic-ferromagnetic-like transition and insulator-metal transition in isostructural LBaCo2O5.5 (L = Sm, Eu, Gd, Tb, Dy, Y), and that the simultaneous octahedral Co1 3z2 - r2 /x2 - y2 (pyramidal Co2 x2 - y2) → Co1 (Co2) yz electron transfer gives rise to the lattice anomaly at TIM. The present study, supporting the author's prior work (Wu H 2001 Phys. Rev. B 64 092413), provides a unified explanation for a number of experimental findings for LBaCo2O5.5

  19. The Bo1-specific PCR marker AWW5L7 is predictive of boron tolerance status in a range of exotic durum and bread wheats.

    Schnurbusch, Thorsten; Langridge, Peter; Sutton, Tim

    2008-12-01

    High soil boron (B) constitutes a major soil problem in many parts of the world, particularly in low-rainfall areas and land under irrigation. Low accumulation of B in the shoot or grain of cereal crops is correlated with the maintenance of biomass production and grain yield under high B conditions, suggesting that this trait is an important component of field tolerance. A novel screening protocol to measure B accumulation in aerated and supported hydroponics was validated using a set of known and exotic bread wheat (Triticum aestivum L.) and durum wheat (Triticum turgidum L. subsp. durum (Desf.) Husn.) accessions. Furthermore, B accumulation in two Triticum urartu Tumanian ex Gandilyan and 54 Triticum monococcum L. accessions was measured and showed considerable phenotypic variation. However, B accumulation in these lines was higher than that observed in the most tolerant durum or bread wheats. Mapping of high B tolerance in the durum population AUS14010/Yallaroi revealed a locus possibly allelic to Bo1, a major source of B toxicity tolerance previously identified in bread wheat. Here, we show that the Bo1-specific codominant PCR marker AWW5L7 is predictive of B tolerance status among exotic durum and bread wheat accessions. All tolerant durum accessions assayed carried very similar AWW5L7 marker fragments, indicating wide distribution of this allele among tolerant durum wheats. Three bread wheat accessions had tolerance that was independent of Bo1 and is probably located on chromosome 4A. These lines represent a valuable genetic resource for B toxicity tolerance breeding in wheat. PMID:19088810

  20. Reference Gene Selection in the Desert Plant <em>Eremosparton songoricuem>m>

    Dao-Yuan Zhang; Yuan-Ming Zhang; Wood, Andrew J.; Xiao-Shuang Li; Hong-Lan Yang

    2012-01-01

    <em>Eremosparton songoricum em>(Litv.) Vass. (<em>E. songoricumem>) is a rare and extremely drought-tolerant desert plant that holds promise as a model organism for the identification of genes associated with water deficit stress. Here, we cloned and evaluated the expression of eight candidate reference genes using quantitative real-time reverse transcriptase polymerase chain reactions. The expression of these candidate reference genes was analyzed in a diverse set...

  1. EM International. Volume 1

    1993-07-01

    It is the intent of EM International to describe the Office of Environmental Restoration and Waste Management`s (EM`s) various roles and responsibilities within the international community. Cooperative agreements and programs, descriptions of projects and technologies, and synopses of visits to international sites are all highlighted in this semiannual journal. Focus on EM programs in this issue is on international collaboration in vitrification projects. Technology highlights covers: in situ sealing for contaminated sites; and remote sensors for toxic pollutants. Section on profiles of countries includes: Arctic contamination by the former Soviet Union, and EM activities with Germany--cooperative arrangements.

  2. Estudio del daño por hidrógeno en uniones soldadas de un acero API 5L X52

    Réquiz, R.

    2008-04-01

    Full Text Available The main objective of the present investigation was to study the susceptibility to hydrogen damage on a type API 5L X52 steel welded by electrical resistance. Several techniques, such as hydrogen permeation and cathodic charging were used. The metallic material was characterized using SEM and TEM. The base metal microstructure was very similar to that one corresponding to the welded area. This microstructure was mainly comprised by ferrite and perlite, differing only in the grain size. Therefore, the susceptibility to hydrogen damage was similar in both cases. It is worth mentioning that the welded area has very small dimensions. Indeed, the fusion zone is only 5 mm wide while the heat affected zone is 1 mm wide. The hydrogen damage observed was mainly in the form of blisters, which were associated to the presence of aluminum rich inclusions. Also, it was noticed partial inclusion dissolution and some matrix attack adjacent to the inclusions.

    En la presente investigación se estudió la susceptibilidad al daño por hidrógeno en un acero API 5L X52 soldado por resistencia eléctrica. Para ello, se emplearon técnicas de permeación y de carga catódica de hidrógeno. El material fue caracterizado mediante microscopía electrónica de barrido y de transmisión. La susceptibilidad al daño por hidrógeno fue similar tanto en el metal base como en el cordón de soldadura. Este comportamiento se vincula a la microestructura homogénea constituida por perlita y ferrita, que presentan ambos, aun cuando existen diferencias en el tamaño de grano. El cordón de soldadura tenía dimensiones muy pequeñas, donde la zona de fusión y la afectada por el calor poseen espesores de 5 mm y 1 mm, respectivamente. El daño inducido por hidrógeno se presentó en forma de ampollas en la superficie del material, asociado, principalmente, a la presencia de inclusiones globulares y semiglobulares ricas en aluminio. Además, se manifestó una disoluci

  3. International EMS Systems

    Langhelle, Audun; Lossius, Hans Morten; Silfvast, Tom;

    2004-01-01

    . Access to on-line medical advice of a physician is not available; (2) Finland: the autonomy of the individual municipalities and their responsibility to cover for primary and specialised health care, as well as the EMS, and the lack of supporting or demanding legislation regarding the EMS; (3) Iceland is...... the only country that has emergency medicine (EM) as a recognised speciality but there is a need for more fully trained specialists in EM; (4) Norway: the ordinary ground ambulance is pointed out as the weakest link in the EM chain and a health reform demands extensive co-operation between the new...... health enterprises to re-establish a nation-wide air ambulance service; (5) Sweden: to create evidence based medicine standards for treatment in emergency medicine, a better integration of all part of the chain of survival, a formalised education in EM and a nation wide physician staffed helicopter EMS...

  4. Complement Receptors C5aR and C5L2 Are Associated with Metabolic Profile, Sex Hormones, and Liver Enzymes in Obese Women Pre- and Postbariatric Surgery

    Reza Rezvani

    2014-01-01

    Full Text Available Objective. Obesity is associated with metabolic dysfunction with sex differences and chronic, low-grade inflammation. We proposed that hepatic expression of immune complement C3 related receptors (C3aR, C5aR, and C5L2 would be associated with pre- or postmenopausal status and metabolic profile in severely obese women. We hypothesized that C5L2/C5aR ratio, potentially influencing the ASP/C5L2 metabolic versus C5a/C5aR immune response, would predict metabolic profiles after weight loss surgery. Materials and Methods. Fasting plasma (hormone, lipid, and enzyme analysis and liver biopsies (RT-PCR gene expression were obtained from 91 women during surgery. Results. Hepatic C5L2 mRNA expression was elevated in pre- versus postmenopausal women (P<0.01 and correlated positively with circulating estradiol, estrone, ApoB, ApoA1, ApoA1/B, waist circumference, age, and LDL-C (all P<0.05. While plasma ASP was lower in pre- versus postmenopausal women (P<0.01, the hepatic C5L2/C5aR mRNA ratio was increased (P<0.001 and correlated positively with estrone (P<0.01 and estradiol (P<0.001 and negatively with circulating ApoB and liver enzymes ALT, AST, and GGT (all P<0.05. Over 12 months postoperatively, liver enzymes in low C5L2/C5aR mRNA ratio group remained higher (ALP and ALT, P<0.05, AST and GGT, P<0.001 2-way-ANOVA. Conclusion. C5L2-C5aR association with other mediators including estrogens may contribute to hepatic metabolic and inflammatory function.

  5. Occurrence and palaeoenvironmental significance of aromatic hydrocarbon biomarkers in Oligocene sediments from the Mallik 5L-38 Gas Hydrate Production Research Well (Canada)

    Haberer, R.M.; Mangelsdorf, K.; Wilkes, H.; Horsfield, B. [Geoforschungszentrum Potsdam, Potsdam (Germany)

    2006-07-01

    The aromatic hydrocarbon biomarker distributions of thirty Oligocene sediment samples with different lithology (lignite, clay and sand) from the JAPEX/JNOC/GSC et al. Mallik 5L-38 Gas Hydrate Production Research Well, Canada, were analyzed using gas chromatography-mass spectrometry (GC-MS). The compositions vary with lithology, indicating a change in palaeoenvironmental conditions at the time of deposition. Aromatic diterpenoids of the abietane type are more abundant in the lignite samples than in the clay samples and represent a gymnosperm (e.g., conifer) dominated palaeovegetation. In contrast, in the clay samples aromatic triterpenoids are generally preserved as major constituents, indicating angiosperm dominated vegetation. The sand samples contain only minor amounts of aromatic terpenoids, but show a preference for diterpenoid gymnosperm markers. To recognise gymnosperm versus angiosperm dominated palaeoenvironments a new ratio, termed the angiosperm-gymnosperm aromatic ratio (AGAR), has been developed. Thus, the terpenoid distribution in the deltaic sediments provides information on the compositional changes in the plant community at the Mallik site (lignites) and the hinterland (clays) over time. Concomitantly, the changing dominance in the plant communities allows an insight into varying climatic conditions during the late Oligocene in the area.

  6. Numerical Evaluation of Temperature Field and Residual Stresses in an API 5L X80 Steel Welded Joint Using the Finite Element Method

    Jailson A. Da Nóbrega

    2016-01-01

    Full Text Available Metallic materials undergo many metallurgical changes when subjected to welding thermal cycles, and these changes have a considerable influence on the thermo-mechanical properties of welded structures. One method for evaluating the welding thermal cycle variables, while still in the project phase, would be simulation using computational methods. This paper presents an evaluation of the temperature field and residual stresses in a multipass weld of API 5L X80 steel, which is extensively used in oil and gas industry, using the Finite Element Method (FEM. In the simulation, the following complex phenomena were considered: the variation in physical and mechanical properties of the material as a function of the temperature, welding speed and convection and radiation mechanisms. Additionally, in order to characterize a multipass weld using the Gas Tungsten Arc Welding process for the root pass and the Shielded Metal Arc Welding process for the filling passes, the analytical heat source proposed by Goldak and Chakravarti was used. In addition, we were able to analyze the influence of the mesh refinement in the simulation results. The findings indicated a significant variation of about 50% in the peak temperature values. Furthermore, changes were observed in terms of the level and profile of the welded joint residual stresses when more than one welding pass was considered.

  7. Detection of gamma-rays with a 3.5 l liquid xenon ionization chamber triggered by the primary scintillation light

    Aprile, E; Chen Dan Li; Muhkerjee, R; Xu Fan

    2002-01-01

    A gridded ionization chamber with a drift length of 4.5 cm and a total volume of 3.5 l, was operated with high-purity liquid xenon and extensively tested with gamma-rays from sup 1 sup 3 sup 7 Cs, sup 2 sup 2 Na and sup 6 sup 0 Co radioactive sources. An electron lifetime in excess of 1 ms was inferred from two independent measurements. The electric field dependence of the collected charge and energy resolution was studied in the range 0.1-4 kV/cm, for different gamma-ray energies. With an electric field of 4 kV/cm, the spectral performance of the detector is consistent with an energy resolution of 5.9% at 1 MeV, scaling with energy as E sup - sup 0 sup . sup 5. The chamber was also used to detect the primary scintillation light produced by gamma-ray interactions in liquid xenon. The light signal was successfully used to trigger the acquisition of the charge signal with a FADC readout. A trigger efficiency of approx 85% was measured at 662 keV.

  8. Development and validation of a real time PCR for the detection of myxoma virus based on the diploid gene M000.5L/R.

    Duarte, Margarida Dias; Barros, Sílvia Carla; Henriques, Ana Margarida; Fagulha, Maria Teresa; Ramos, Fernanda; Luís, Tiago; Fevereiro, Miguel

    2014-02-01

    The myxoma virus (MYXV) causes severe infections in European rabbits that may reach mortality rates up to 100% depending on the viral strain. The typical symptoms and lesions induced by the virus are usually enough to permit the correct clinical diagnosis. However, in peracute forms the infection may be accompanied by unspecific symptoms. Sudden death may also occur without evident clinical signs of myxomatosis. Likewise, a clinical diagnosis of atypical forms of myxomatosis (amyxomatous) is often complicated and delayed due to the scarceness of skin lesions. As the disease control often depends on an early and unequivocal diagnosis of MYXV, laboratorial methods play a relevant role in the confirmation of MYXV infection. This study describes the development and validation of a novel, high accurate real time polymerase chain reaction assay (rtPCR) for the detection of MYXV. Primers were designed to amplify a 125-bp within the gene M000.5L/R, which is duplicated in the termini of the genome and is unique among Leporipoxvirus. The assay was negative for SFV and other poxviruses and was able to detect 2.6 copies of MYXV DNA proving the effectiveness, specificity and sensitivity of this diagnosis tool. The rtPCR has been applied successfully in INIAV laboratory for routine diagnosis of myxomatosis since 2005. PMID:24300832

  9. Pengaruh Variasi Goresan Lapis Lindung Dan Variasi pH Tanah Terhadap Arus Proteksi Sistem Impressed Current Cathodic Protection (ICCP Pada Pipa API 5L Grade B

    Trendy Leo Pratama

    2015-03-01

    Full Text Available Korosi merupakan penyebab utama terjadinya kegagalan material pipeline akibat berinteraksi secara langsung dengan lingkungan. Pemberian lapis lindung yang selama ini menjadi pilihan utama untuk mengontrol korosi tidak selamanya bisa diandalkan. Hal ini disebabkan kemungkinan terjadinya kerusakan lapis lindung selama proses shipping atau instalasi sangatlah besar. Oleh karena itu sering kali pemberian lapis lindung dikolaborasikan dengan perlindungan sistem proteksi katodik, khususnya sistem arus paksa (ICCP. Penelitian ini bertujuan mempelajari pengaruh luas goresan lapis lindung dan pH tanah terhadap arus proteksi sistem proteksi katodik arus paksa (ICCP. Goresan yang diberikan berbentuk lingkaran dan persegi panjang dengan luas 10 mm2, 50 mm2, 100 mm2, 150 mm2, 250 mm2, dan 500 mm2. Spesimen tanpa goresan dan tanpa lapis lindung digunakan sebagai pembanding. Sedangkan untuk variasi pH tanahnya adalah pH 3 (asam, pH 7 (netral, dan pH 11 (basa. Pipa API 5L grade B digunakan sebagai katoda dan grafit sebagai anoda, serta rectifier sebagai penyearah arus (DC. Arus proteksi ICCP diatur hingga mencapai nilai potensial proteksi -850 mV vs elektroda Cu/CuSO4. Setelah dilakukan pengkondisian awal selama 8 hari dan 7 hari pengukuran arus, didapatkan hasil bahwa semakin semakin besar goresan lapis lindung maka semakin besar arus proteksi yang dibutuhkan dalam kondisi pH tanah yang sama. Sedangkan dalam kondisi luas goresan yang sama, kebutuhan arus proteksi meningkat seiring dengan semakin rendahnya pH tanah (semakin asam

  10. Evaluation of the susceptibility to pitting corrosion of steel api 5L x42 exposed to solutions containing chloride ions and CO{sub 2} by electrochemical noise measurements; Evaluacion de la susceptibilidad a la corrosion por picado del acero api 5l x42 expuesto a un ambiente con cloruros y CO{sub 2} mediante la tecnica de ruido electroquimico

    Pena-Ballesteros, D.; Rodriguez-Vanegas, N.; Anteliz, C.; Sarmiento Klapper, H.

    2011-07-01

    The concentration of chloride ions and the partial pressure of CO{sub 2} play an important role in the degradation of low-carbon steels used for the construction of pipelines in oil and gas industry. In order to evaluate the susceptibility of carbon steel API 5L X42 to pitting corrosion electrochemical noise and linear polarization resistance measurements were carried out in aqueous solutions containing chloride ions and CO{sub 2}. The concentration of chloride ions was varied between, 10000 and 18000 ppm, and the CO{sub 2} partial pressure between 10 psi and 18 psi. Experimental results pointed out that the formation of protective layer, consisting mainly of FeCO{sub 3}, depends on the partial pressure of CO{sub 2} in the system. Nevertheless, the stability of this layer was considerably affected by increasing the concentration of chloride ions causing that localized corrosion has taken place in some areas of the surface of API 5L X42, which were detected by electrochemical noise technique. (Author) 10 refs.

  11. International EMS Systems

    Langhelle, Audun; Lossius, Hans Morten; Silfvast, Tom;

    2004-01-01

    Emergency medicine service (EMS) systems in the five Nordic countries have more similarities than differences. One similarity is the involvement of anaesthesiologists as pre-hospital physicians and their strong participation for all critically ill and injured patients in-hospital. Discrepancies do....... Access to on-line medical advice of a physician is not available; (2) Finland: the autonomy of the individual municipalities and their responsibility to cover for primary and specialised health care, as well as the EMS, and the lack of supporting or demanding legislation regarding the EMS; (3) Iceland...... is the only country that has emergency medicine (EM) as a recognised speciality but there is a need for more fully trained specialists in EM; (4) Norway: the ordinary ground ambulance is pointed out as the weakest link in the EM chain and a health reform demands extensive co-operation between the new health...

  12. The new 2.5L L4 gasoline engine for LEXUS IS300h. The renewed engine series for FR hybrid vehicles

    Ishiguro, Fumihisa; Mashiki, Zenichiro; Yamanari, Kenji [Toyota Motor Corporation, Aichi (Japan)

    2013-08-01

    To ensure future sustainable mobility, vehicles have to face crucial problems such as energy security, global warming and air quality. To address these problems, TOYOTA introduced in 1997 the TOYOTA Hybrid System (THS) and has continuously improved its technology, globally contributing to the environmental improvement by its expansion into many markets in the world. TOYOTA presented the renewed 4 Cylinder Engine Series for FF vehicles at this symposium last year. This year, Toyota presents the result of its continuous development for FR Hybrid Vehicles, especially for D and E segment vehicles. Toyota not only improved thermal efficiency and reduced CO{sub 2} but also achieved high power output. In 2012, TOYOTA launched 3.5L V6 engine for LEXUS-GS (2GR-FXE engine), as first engine of this new engine series. In 2013, TOYOTA will launch 2.5L-L4 engine for LEXUS-IS (2AR-FSE engine), as the leading engine of this series. Toyota developed these new engines, aiming at leadership with regard to fuel economy, clean exhaust gas and high reliability. Toyota carried out modifications, taking into account usage of Hybrid System. With targeting highest levels of environmental performance, Toyota improved the vehicle driving performances like acceleration response by the combination of enhanced engine power output and newly developed Hybrid System. One of the biggest feature of this series is new generation D-4S system, including two injectors (for Direct injection and Port injection) for each cylinder, high fuel pressure (greater than 18MPa) and high fuel flow rate. The new generation D-4S system helps achieving high performance and good thermal efficiency. Furthermore, Toyota added on Cooled EGR system to 2AR-FSE engine, contributing to lower the fuel consumption, especially in highway driving. The very low friction technology and the well proven Atkinson Cycle are also key features of this engine series. Thanks to the above features, the new engine series achieves high

  13. Effect of orbital automatic welding on the weld metal mechanical properties in API 5L X65 natural gas transmission pipe

    Baek, J.-H.; Kim, Y.-P.; Kim, W.-S. [Korea Gas Corp., Ansan (Korea, Republic of)

    2000-07-01

    Most natural gas transmission pipelines in Korea have been constructed using a manual welding processes but major gas companies are looking into the advantages of an automatic process for girth welding. The automatic welding process is divided into gas tungsten arc welding (GTAW) and gas-metal-arc welding (GMAW) processes. GTAW uses an inert gas such as argon to shield weld metal from the atmosphere during welding and a 0.9-1.6 mm solid wire. Filler metals used in the GMAW process are classified into solid wire and flux cored wire. In this study, Charpy impact tests, crack tip opening tests and micro-hardness tests were conducted on a steel pipeline to determine the effects of weld metal composition and microstructure on the toughness of weld metal. API 5L X65 steel pipes with 17.5 mm wall thickness and 762 mm outer diameter were welded using an orbital automatic welding process. Flux cored arc welding (FCAW) and GTAW were used to evaluate the automatic welding process. Manual welds were done using GTAW with ER70S-G filler metal for the root pass and shielded metal arc welding with low hydrogen E9016-G electrode for the remaining passes. It was concluded that the filler metals with the highest fracture toughness were E80T1-K2 and E71T-1 using the FCAW process and ER80S-G using the GTAW process. The filler metals with the correct hardness were E800T1-K2 and E71T-1 using the FCAW process. 13 refs., 3 tabs., 4 figs.

  14. Overview of pressure drawdown production test results for the Japex/JNOC/GSC Mallik 5L-38 gas hydrate research well

    Hancock, S.; Carle, D. [APA Petroleum Engineering Ltd., Calgary, AB (Canada); Dallimore, S. [Geological Survey of Canada, Sidney, BC (Canada); Collett, T. [United States Geological Survey, Denver, CO (United States); Satoh, T. [Japan Petroleum Exploration Co. Ltd., Tokyo (Japan); Inoue, T. [Japan National Oil Corp., Chiba (Japan)

    2004-07-01

    Schlumberger's Modular Dynamic Tester (MDT) cased hole wireline tool was used during a pressure drawdown production test at the Mallik 5L-38 well to successfully test 3 separate hydrate intervals as well as free gas and water zones. The MDT test was initially performed to reduce reservoir pressure below the hydrate stability point, and to shut-in and observe the pressure build-up. It was assumed that the rate of gas production would be too small to measure, so the rate of hydrate dissociation would have to be inferred from changing pressure versus time data. Two important phenomena were observed during the hydrate tests: (1) free gas was produced on a steady state basis following the initial clean-up flow of water, and (2) the pressure response upon shut-in displayed porous media effects and indicated both flow contribution and pressure effects beyond the surface area of the hydrate open to the wellbore. In response to these observations, the MDT test procedures for the hydrate intervals were changed to include multiple flow and build-up periods, as well as injection and pressure fall-off periods. The factors that should be considered in interpreting the pressure transient data obtained during the MDT tests of the hydrate intervals include wellbore and perforation geometry with respect to the pressure affected area in the reservoir; radial and time dependent hydrate saturation changes which result in dynamic multiphase fluid flow, changing relative permeability, and changing system compressibility; the addition of free gas during the shut-in periods from continued hydrate dissociation; and the changing presence and character of boundaries due either to localized fractures or the limit of the hydrate dissociation front. Since analytical pressure transient analysis software cannot incorporate such dynamic reservoir parameters, conventional analytical techniques were used to evaluate the test data. 1 fig.

  15. Isolation and Characterization of a Lycopene ε-Cyclase Gene of <em>Chlorella em>(Chromochloris> <em>zofingiensis>. Regulation of the Carotenogenic Pathway by Nitrogen and Light

    Maria Angeles Vargas

    2012-09-01

    Full Text Available The isolation and characterization of the lycopene ε-cyclase gene from the green microalga <em>Chlorella em>(Chromochloris> <em>zofingiensis> (<em>Czlcy-e> was performed. This gene is involved in the formation of the carotenoids α-carotene and lutein. <em>Czlcy-e> gene encoded a polypeptide of 654 amino acids. A single copy of <em>Czlcy-e> was found in <em>C. zofingiensisem>. Functional analysis by heterologous complementation in <em>Escherichia coliem> showed the ability of this protein to convert lycopene to δ-carotene. In addition, the regulation of the carotenogenic pathway by light and nitrogen was also studied in <em>C. zofingiensisem>. High irradiance stress did not increase mRNA levels of neither lycopene β<em>->cyclase gene (<em>lcy-b> nor lycopene ε-cyclase gene<em> em>(lcy-e> as compared with low irradiance conditions, whereas the transcript levels of <em>psy>, <em>pds>, <em>chyB> and <em>bkt> genes were enhanced, nevertheless triggering the synthesis of the secondary carotenoids astaxanthin, canthaxanthin and zeaxanthin and decreasing the levels of the primary carotenoids α-carotene, lutein, violaxanthin and β-carotene. Nitrogen starvation <em>per seem> enhanced mRNA levels of all genes considered, except <em>lcy-e and pdsem>, but did not trigger the synthesis of astaxanthin, canthaxanthin nor zeaxanthin. The combined effect of both high light and nitrogen starvation stresses enhanced significantly the accumulation of these carotenoids as well as the transcript levels of <em>bkt> gene, as compared with the effect of only high irradiance stress.

  16. Emergency Medical Service (EMS) Stations

    Kansas Data Access and Support Center — EMS Locations in Kansas The EMS stations dataset consists of any location where emergency medical services (EMS) personnel are stationed or based out of, or where...

  17. Caracterización de Revestimientos de Niobio formados por Aspersión Térmica a Plasma sobre Acero API 5l X65 Characterization of Niobium Coatings obtained by Plasma Spray Thermal Substrate on Steel API 5l X651

    José F Matos; Felipe P Motta; Ester S Rieder; Célia F. Malfatti

    2012-01-01

    Se evaluó la morfología y el comportamiento electroquímico del revestimiento de niobio obtenido por el proceso de aspersión térmica a plasma en substrato de acero API 5L X65. El revestimiento con niobio se realizó con una corriente eléctrica de 500 A, flujo de polvo metálico de niobio de 15 g/min y gas de argón de 2.0 L/min. La preparación superficial del substrato se realiza con pre-calentamiento y limpieza a presión con abrasivo de alúmina. La morfología del revestimiento fue analizada por ...

  18. The <em>Opuntia streptacanthaem> <em>OpsHSP18 em>Gene Confers Salt and Osmotic Stress Tolerance in <em>Arabidopsis thalianaem>

    Juan Francisco Jiménez-Bremont

    2012-08-01

    Full Text Available Abiotic stress limits seed germination, plant growth, flowering and fruit quality, causing economic decrease. Small Heat Shock Proteins (sHSPs are chaperons with roles in stress tolerance. Herein, we report the functional characterization of a cytosolic class CI sHSP (OpsHSP18 from <em>Opuntia streptacantha em>during seed germination in <em>Arabidopsis thalianaem> transgenic lines subjected to different stress and hormone treatments. The over-expression of the <em>OpsHSP18em> gene in <em>A. thalianaem> increased the seed germination rate under salt (NaCl and osmotic (glucose and mannitol stress, and in ABA treatments, compared with WT. On the other hand, the over-expression of the <em>OpsHSP18em> gene enhanced tolerance to salt (150 mM NaCl and osmotic (274 mM mannitol stress in <em>Arabidopsis> seedlings treated during 14 and 21 days, respectively. These plants showed increased survival rates (52.00 and 73.33%, respectively with respect to the WT (18.75 and 53.75%, respectively. Thus, our results show that <em>OpsHSP18em> gene might have an important role in abiotic stress tolerance, in particular in seed germination and survival rate of Arabidopsis plants under unfavorable conditions.

  19. Expression of Selected <em>Ginkgo em>>biloba em>Heat Shock Protein Genes After Cold Treatment Could Be Induced by Other Abiotic Stress

    Feng Xu

    2012-05-01

    Full Text Available Heat shock proteins (HSPs play various stress-protective roles in plants. In this study, three <em>HSP> genes were isolated from a suppression subtractive hybridization (SSH cDNA library of <em>Ginkgo bilobaem> leaves treated with cold stress. Based on the molecular weight, the three genes were designated <em>GbHSP16.8em>, <em>GbHSP17em> and <em>GbHSP70em>. The full length of the three genes were predicted to encode three polypeptide chains containing 149 amino acids (Aa, 152 Aa, and 657 Aa, and their corresponding molecular weights were predicted as follows: 16.67 kDa, 17.39 kDa, and 71.81 kDa respectively. The three genes exhibited distinctive expression patterns in different organs or development stages. <em>GbHSP16.8em> and <em>GbHSP70em> showed high expression levels in leaves and a low level in gynoecia, <em>GbHSP17em> showed a higher transcription in stamens and lower level in fruit. This result indicates that <em>GbHSP16.8em> and <em>GbHSP70 em>may play important roles in <em>Ginkgo> leaf development and photosynthesis, and <em>GbHSP17em> may play a positive role in pollen maturation. All three <em>GbHSPs> were up-regulated under cold stress, whereas extreme heat stress only caused up-regulation of <em>GbHSP70em>, UV-B treatment resulted in up-regulation of <em>GbHSP16.8em> and <em>GbHSP17em>, wounding treatment resulted in up-regulation of <em>GbHSP16.8em> and <em>GbHSP70em>, and abscisic acid (ABA treatment caused up-regulation of <em>GbHSP70em> primarily.

  20. Caracterización de Revestimientos de Niobio formados por Aspersión Térmica a Plasma sobre Acero API 5l X65 Characterization of Niobium Coatings obtained by Plasma Spray Thermal Substrate on Steel API 5l X651

    José F Matos

    2012-01-01

    Full Text Available Se evaluó la morfología y el comportamiento electroquímico del revestimiento de niobio obtenido por el proceso de aspersión térmica a plasma en substrato de acero API 5L X65. El revestimiento con niobio se realizó con una corriente eléctrica de 500 A, flujo de polvo metálico de niobio de 15 g/min y gas de argón de 2.0 L/min. La preparación superficial del substrato se realiza con pre-calentamiento y limpieza a presión con abrasivo de alúmina. La morfología del revestimiento fue analizada por microscopía electrónica de barrido (MEB, la rugosidad de la superficie se evaluó por perfilometría, la dureza por micro-dureza Vickers y la adherencia por ensayado de doblado a 180°. La resistencia a la corrosión del revestimiento se determinó mediante el ensayo de polarización en una solución de NaVl 3,5%. A partir de los resultados obtenidos fue posible verificar que el revestimiento presentó fisuras y poros entre las placas rociadas además de una dureza elevada en relación al substrato y adherencia no adecuada. Aún así los valores de densidad de corriente desarrollados por el sistema en comparación al acero revestido se redujeron.The morphology and electrochemical behavior of niobium coating obtained by thermal plasma spray process on a substrate of steel API 5L X65 was evaluated. The coating was obtained, using electrical current of 500 A, 15 g/min of powder and 2.0 L/min of argon gas. The preparation of the substrate surface was performed with preheating and abrasive blasting with alumina. After thermal spraying, the morphology of the coating was analyzed by scanning electron microscopy (SEM, while the surface roughness was evaluated by profilometry, hardness by Vickers microhardness test and adhesion by bending at 180 °. The corrosion resistance of the coating was evaluated from the polarization test in 3.5% NaVl solution. The results show that the coating presented cracking and lack of padding between the plates sprayed

  1. Osteoartrites em equinos

    Rocha, Francisco José Martins

    2008-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária A Osteoartrite (OA) é a principal causa de claudicação no cavalo de desporto e lazer, sendo uma afecção que tem grandes repercussões económicas. Este trabalho descreve algumas das características importantes da estrutura articular, bem como da sua fisiologia. Define a OA e todas as estruturas envolvidas no seu processo. Os mecanismos fisiopatológicos põem em evidência os factores de risco em causa e que determinam tod...

  2. A creche em Portugal

    Serrano, Leonor; Pinto, Jorge

    2015-01-01

    Na evolução das creches em Portugal verifica-se uma alternância entre conceções assistencialista de integração educacional. Procura-se refletir sobre a tensão existente entre estas duas perspetivas relativamente ao atendimento em creche em Portugal. A creche foi considerada como local de guarda por impedimento dos pais, no entanto no decurso dos tempos assistimos a tentativas de a assumir como um serviço de prestação de cuidados e de educação promovendo um desenvolvimento mais holístico e res...

  3. Homeopatia em Pediatria

    Pinto, Ana Isabel Alves

    2013-01-01

    Numa sociedade em constante processo de formação e de informação, não conhecer determinada terapia não pode ser a resposta de um profissional de farmácia ao seu utente. A divulgação massiva de tratamentos naturalistas, alternativos e baseados em saberes ancestrais, frequentemente entram em conflito com as prescrições médicas e aconselhamentos farmacêuticos. Com as medicinas alternativas a ganhar terreno paulatinamente, como se observa com a utilização da acupunctura e de fitote...

  4. Glycosylation of Vanillin and 8-Nordihydrocapsaicin by Cultured <em>Eucalyptus perrinianaem> Cells

    Naoji Kubota

    2012-05-01

    Full Text Available Glycosylation of vanilloids such as vanillin and 8-nordihydrocapsaicin by cultured plant cells of <em>Eucalyptus perrinianaem> was studied. Vanillin was converted into vanillin 4-<em>O>-b-D-glucopyranoside, vanillyl alcohol, and 4-<em>O>-b-D-glucopyranosylvanillyl alcohol by <em>E. perriniana em>cells. Incubation of cultured <em>E. perrinianaem> cells with 8-nor- dihydrocapsaicin gave 8-nordihydrocapsaicin 4-<em>O>-b-D-glucopyranoside and 8-nordihydro- capsaicin 4-<em>O>-b-D-gentiobioside.

  5. Study of the <em>in Vitroem> Antiplasmodial, Antileishmanial and Antitrypanosomal Activities of Medicinal Plants from Saudi Arabia

    Nawal M. Al-Musayeib

    2012-09-01

    Full Text Available The present study investigated the <em>in vitroem> antiprotozoal activity of sixteen selected medicinal plants. Plant materials were extracted with methanol and screened <em>in vitroem> against erythrocytic schizonts of <em>Plasmodium falciparumem>, intracellular amastigotes of <em>Leishmania infantum em>and <em>Trypanosoma cruzi em>and free trypomastigotes of<em> T. bruceiem>. Cytotoxic activity was determined against MRC-5 cells to assess selectivity<em>. em>The criterion for activity was an IC50 < 10 µg/mL (4. Antiplasmodial activity was found in the<em> em>extracts of<em> em>>Prosopis julifloraem> and <em>Punica granatumem>. Antileishmanial activity<em> em>against <em>L. infantumem> was demonstrated in <em>Caralluma sinaicaem> and <em>Periploca aphylla.em> Amastigotes of<em> T. cruzi em>were affected by the methanol extract of<em> em>>Albizia lebbeckem>> em>pericarp, <em>Caralluma sinaicaem>,> Periploca aphylla em>and <em>Prosopius julifloraem>. Activity against<em> T. brucei em>was obtained in<em> em>>Prosopis julifloraem>. Cytotoxicity (MRC-5 IC50 < 10 µg/mL and hence non-specific activities were observed for<em> em>>Conocarpus lancifoliusem>.>

  6. Purification, Characterization and Antioxidant Activities <em>in Vitroem>> em>and <em>in Vivoem> of the Polysaccharides from <em>Boletus edulisem> Bull

    Yijun Fan

    2012-07-01

    Full Text Available A water-soluble polysaccharide (BEBP was extracted from <em>Boletus edulis em>Bull using hot water extraction followed by ethanol precipitation. The polysaccharide BEBP was further purified by chromatography on a DEAE-cellulose column, giving three major polysaccharide fractions termed BEBP-1, BEBP-2 and BEBP-3. In the next experiment, the average molecular weight (Mw, IR and monosaccharide compositional analysis of the three polysaccharide fractions were determined. The evaluation of antioxidant activities both <em>in vitroem> and <em>in vivo em>suggested that BEBP-3 had good potential antioxidant activity, and should be explored as a novel potential antioxidant.

  7. A specimen of <em>Sorex> cfr. <em>samniticus> in Barn Owl's pellets from Murge plateau (Apulia, Italy / Su di un <em>Sorex> cfr. <em>samniticus> (Insectivora, Soricidae rinvenuto in borre di <em>Tyto albaem> delle Murge (Puglia, Italia

    Giovanni Ferrara

    1992-07-01

    Full Text Available Abstract In a lot of Barn Owl's pellets from the Murge plateau a specimen of <em>Sorex> sp. was detected. Thank to some morphological and morphometrical features, the cranial bones can be tentatively attributed to <em>Sorex samniticusem> Altobello, 1926. The genus <em>Sorex> was not yet included in the Apulia's fauna southwards of the Gargano district; the origin and significance of the above record is briefly discussed, the actual presence of a natural population of <em>Sorex> in the Murge being not yet proved. Riassunto Viene segnalato il rinvenimento di un esemplare di <em>Sorex> cfr. <em>samniticus> da borre di <em>Tyto albaem> delle Murge. Poiché il genere non era stato ancora segnalato nella Puglia a sud del Gargano, viene discusso il significato faunistico del reperto.

  8. <em>In Vivoem> Histamine Optical Nanosensors

    Heather A. Clark

    2012-08-01

    Full Text Available In this communication we discuss the development of ionophore based nanosensors for the detection and monitoring of histamine levels <em>in vivoem>. This approach is based on the use of an amine-reactive, broad spectrum ionophore which is capable of recognizing and binding to histamine. We pair this ionophore with our already established nanosensor platform, and demonstrate <em>in vitroem> and <em>in vivoem> monitoring of histamine levels. This approach enables capturing rapid kinetics of histamine after injection, which are more difficult to measure with standard approaches such as blood sampling, especially on small research models. The coupling together of <em>in vivoem> nanosensors with ionophores such as nonactin provide a way to generate nanosensors for novel targets without the difficult process of designing and synthesizing novel ionophores.

  9. Parasitic zoonoses: survey in foxes (<em>Vulpes vulpesem>) in the northern Apennines / Zoonosi parassitarie: indagini in volpi (<em>Vulpes vulpesem>) dell'Appennino settentrionale

    Vittorio Guberti; Giovanni Poglayen

    1991-01-01

    Abstract A parasitological survey on 153 foxes was carried out in the northern Apennines, during the period 1984-1987. The following parasites were identified: <em>Toxocara canisem> (46.4%), <em>Taenia> sp. (17%), <em>Uncinaria stenocephalaem> (11.8%), <em>Mesocestoides lineatusem> (11.1%), <em>Ancylostoma caninumem> (3.9%), <em>Taenia hydatigenaem> (3.3%), <em>Trichuris v...

  10. Burnout em cuidados paliativos

    Simões, Sílvia Cristina Almeida

    2013-01-01

    Dissertação apresentada ao Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessário à obtenção de grau de Mestre em Cuidados Paliativos. O presente trabalho foi realizado no âmbito do 3º semestre do 1º Curso de Mestrado em Cuidados Paliativos, da Escola Superior de Saúde Dr. Lopes Dias. O trabalho encontra-se estruturado em quatro capítulos: o primeiro diz respeito ao relatório da prática clínica, o segundo aborda o enquadramento teórico sobre a Síndrome de Bur...

  11. Evaluation of Pseudopteroxazole and Pseudopterosin Derivatives against <em>Mycobacterium> <em>tuberculosis> and Other Pathogens

    McCulloch, Malcolm W. B.; Brad Haltli; Marchbank, Douglas H.; Kerr, Russell G.

    2012-01-01

    Pseudopterosins and pseudopteroxazole are intriguing marine natural products that possess notable antimicrobial activity with a commensurate lack of cytotoxicity. New semi-synthetic pseudopteroxazoles, pseudopteroquinoxalines and pseudopterosin congeners along with simple synthetic mimics of the terpene skeleton were synthesized. In order to build structure-activity relationships, a set of 29 new and previously reported compounds was assessed for <em>in> <em>vitro...

  12. Ulisses em Kafka

    Stéphane Mosès

    2015-02-01

    Full Text Available ResumoEm sua introdução para Exegese de uma lenda, Stéphane Mosès afirma que a obra de Kafka não necessita de novas interpretações, mas sim de uma “análise rigorosa de sua lógica subjacente”. Assim, em “Ulisses em Kafka”, investigandoa dialética formal de “O silêncio das sereias”, Mosès procura expor a estrutura narrativa que comandaria esse breve texto em que o escritor tcheco acrescenta à astucia de Ulisses a ingenuidade como elemento de salvação.Palavras-chave: Kafka; dialética; salvação.AbstractIn his introduction to Exegèse d’une légende, Stéphane Mosès affirms that Kafka’s works are not in need of new interpretations, but rather, of a “rigorous analysis of their underlying logic”. Thus, in “Ulisses chez Kafka”, by investigating the formal dialectic of “Das Schweigen der Sirenen”, Mosès seeks to exhibit the narrative structure that would supposedly guide this short text in which the Czech author adds naïveté to Ulisses’s cunning intelligence as an element of salvation.Keywords: Kafka; dialectic; salvation.Stéphane Mosès foi professor emérito da Universidade Hebraica de Jerusalém, onde ensinou Literatura Alemã e Comparada, entre os seus principais interesses estavam o pensamento de Franz Rosenzweig e de Walter Benjamin e as literaturas de Franz Kafka e de Paul Célan. Autor de diversos livros, entre eles: L'ange de l'histoire. Rosenzweig, Benjamin, Scholem, Exégèse d'une légende, lectures de Kafka, e Rêves de Freud. Six lectures.Rodrigo Ielpo é doutor em literatura francesa pela UFRJ e em História e Semiologia do texto e da imagem pela Université Paris VII, com pós-doutorado em Teoria Literária pela UNICAMP. Professor Adjunto do Departamento de Letras Neolatinas da Universidade Federal do Rio de Janeiro, possui publicações e traduções nos seguintes temas: teoria e literatura francesa contemporâneas, escrita e processos de subjetivação.rodrigoielpo@gmail.com 

  13. Horizontal Transmission of the Entomopathogen Fungus <em>Metarhizium anisopliae em>in <em>Microcerotermes diversusem> Groups

    Mohammad Saied Mossadegh

    2012-08-01

    Full Text Available An experiment was carried out in order to investigate fungal conidia transmission of <em>Metarhizium anisopliae em>(Metschnikoff> em>Sorokin from vector (donor to healthy <em>Microcerotermes diversusem> Silvestri (Iso.: Termitidae and determine the best donor/concentration ratio for transmission. After preliminary trials, concentrations of 3.1 × 104, 3.9 × 105, 3.2 × 106 and 3.5 × 108 conidia mL−1 were selected for testing. The experiment was performed at three donor : Recipient ratios of 10, 30 and 50%. The highest mortality of recipient workers was observed after 14 days at the concentration of 3.5 × 108 conidia mL−1 and donor ratio of 50%. The mortality of recipient workers was less than 20% at all concentrations at a donor ratio of 10%. Our observations indicate social behavior of <em>M. diversusem>, such as grooming, can be effective in promoting epizootic outbreaks in a colony. While the current results suggest good potential for efficacy, the use of <em>M. anisopliaeem> as a component of integrated pest management of <em>M. diversusem> still needs to be proven under field conditions.

  14. Fumigant Antifungal Activity of Myrtaceae Essential Oils and Constituents from <em>Leptospermum petersoniiem> against Three <em>Aspergillus> Species

    Il-Kwon Park

    2012-09-01

    Full Text Available Commercial plant essential oils obtained from 11 Myrtaceae plant species were tested for their fumigant antifungal activity against <em>Aspergillus ochraceusem>, <em>A. flavusem>, and <em>A. nigerem>. Essential oils extracted from<em> em>Leptospermum> <em>petersonii> at air concentrations of 56 × 10−3 mg/mL and 28 × 10−3 mg/mL completely inhibited the growth of the three <em>Aspergillus> species. However, at an air concentration of 14 × 10−3 mg/mL, inhibition rates of <em>L. petersoniiem> essential oils were reduced to 20.2% and 18.8% in the case of <em>A. flavusem> and <em>A. nigerem>, respectively. The other Myrtaceae essential oils (56 × 10−3 mg/mL only weakly inhibited the fungi or had no detectable affect. Gas chromatography-mass spectrometry analysis identified 16 compounds in <em>L. petersoniiem>> em>essential> em>oil.> em>The antifungal activity of the identified compounds was tested individually by using standard or synthesized compounds. Of these, neral and geranial inhibited growth by 100%, at an air concentration of 56 × 10−3 mg/mL, whereas the activity of citronellol was somewhat lover (80%. The other compounds exhibited only moderate or weak antifungal activity. The antifungal activities of blends of constituents identified in <em>L. petersoniiem> oil indicated that neral and geranial were the major contributors to the fumigant and antifungal activities.

  15. Masculinização de larvas de tilápia do Nilo (<em>Oreochromis niloticusem>) por banhos de imersão e o andrógeno dissolvido em solução de dimetilsulfóxido (DMSO) - DOI: 10.4025/actascianimsci.v26i2.1867 Masculinizaton of Nile tilápia fries (<em>Oreochromis niloticusem>) through bath immersion and androgen dissolved in dimethilsulfoxide (DMSO) solution - DOI: 10.4025/actascianimsci.v26i2.1867

    Fábio Meurer; Carmino Hayashi; Robie Allan Bombardelli; Darci Carlos Fornari

    2004-01-01

    O experimento constituiu-se de dois ensaios. O primeiro objetivou determinar a concentração de dimetilsulfóxido não-prejudicial às larvas de tilápia do Nilo (Oreochromis niloticus L.) para utilização em banhos de imersão, e o segundo avaliou a masculinização e o desempenho zootécnico das larvas submetidas à imersão em diferentes concentrações hormonais. Os animais foram imersos por 36 horas em recipientes de 0,5L, com 50 larvas. No primeiro ensaio, utilizaram-se as concentrações de 0,04%; 0,1...

  16. Espondiloptose em atleta

    Ana Paula Luppino Assad

    2014-06-01

    Full Text Available Os atletas adolescentes estão sob maior risco de lombalgia e lesões estruturais da coluna. A espondilólise é responsável pela maioria das lombalgias em jovens esportistas e raramente ocorre em adultos. Relatamos o caso de uma paciente de 13 anos, atleta de judô, que chegou a nosso serviço com quadro de cinco meses de lombalgia progressiva durante os treinos, sendo inicialmente atribuída a causas mecânicas, sem que houvesse uma investigação mais detalhada por métodos de imagem. Na admissão já apresentava deformidade lombar, postura antálgica e manobra de hiperextensão lombar em unipodálico positiva bilateralmente. Realizou-se investigação, que evidenciou espondiloptose, sendo, então, submetida a tratamento cirúrgico. Com base neste relato de caso, discutimos a abordagem diagnóstica de lombalgia em atletas jovens, uma vez que a queixa de lombalgia crônica pode ser marcador de uma lesão estrutural, a qual pode ser definitiva e trazer perda funcional irreversível.

  17. 嗜麦芽寡养单胞菌降解羽毛5L发酵罐工业小试过程研究%Study on Stenotrophomonas maltophilia DHHJ fermentation in5 L fermenter pilot plant

    鲁丹; 曹张军; 周美华

    2009-01-01

    In order to industrialize the utilization of waste feather by microbiological method,the scale-upof fermentation from shaking flask to 5 L fermenter for Stenotrophomonas maltophilia DHHJ based on the study of fermentation in erlenmeyer flask was investigated.Further,this paper analyzed the fermentation process and optimized the technological parameters.The changes of material and energy in metabolic processes were conjectured,and the product formation of DHHJ batch fermentation kinetics was studied.Finally,under the circumstances of O.08 MPa pressure,2.5 L/min air flow.defined temperature of 40 ℃ and other controlled conditions,this yield was 1~2 fold higher in comparison with the shaking flask fermentation,fermentation period shortened by one day.And it provided the reliable basis for the use of the feather waste.%为了将微生物处理羽毛工艺产业化,在摇瓶发酵条件优化的基础上进行5 L发酵罐工业小试研究,确定了放大发酵条件并根据发酵条件记录对发酵过程进行分析,推测代谢过程中的物质及能量变化及产物形成的动力学模型.在通气气压为0.08 MPa,空气流量为2.5 L/min及恒温40℃的条件下,产物得率比摇瓶发酵提高了2~3倍,发酵周期缩短了l d.为羽毛废弃物的利用提供了可靠的依据.

  18. Ultrasound-Assisted Extraction of Syringin from the Bark of <em>Ilex em>rotunda> Thumb Using Response Surface Methodology

    Hui Wang

    2012-06-01

    Full Text Available In this work, a rapid extraction method based on ultrasound-assisted extraction (UAE of syringin from the bark of <em>Ilex rotunda em>Thumb using response surface methodology (RSM is described. The syringin was analyzed and quantified by high performance liquid chromatography coupled with UV detection (HPLC-UV. The extraction solvent, extraction temperature and extraction time, the three main factors for UAE, were optimized with Box-Behnken design (BBD to obtain the highest extraction efficiency. The optimal conditions were the use of a sonication frequency of 40 kHz, 65% methanol as the solvent, an extraction time of 30 min and an extraction temperature of 40 °C. Using these optimal conditions, the experimental values agreed closely with the predicted values. The analysis of variance (ANOVA indicated a high goodness of model fit and the success of the RSM method for optimizing syringin extraction from the bark of <em>I>. em>rotunda>.

  19. Classe social: conceitos e esquemas operacionais em pesquisa em saude

    Rita Barradas Barata

    2013-08-01

    Full Text Available Discute-se a utilização do conceito de classe em pesquisas em saúde, as diferentes abordagens sociológicas de estratificação social e de estrutura de classes, o potencial explicativo do conceito em estudos de determinação social e desigualdades em saúde, os modelos de operacionalização elaborados para uso em pesquisas sociológicas, demográficas ou de saúde e os limites e possibilidades desses modelos. Foram destacados quatro modelos de operacionalização: de Singer para estudo da distribuição de renda no Brasil, adaptado por Barros para uso em pesquisas epidemiológicas; de Bronfman & Tuirán para o censo demográfico mexicano, adaptado por Lombardi et al para pesquisas epidemiológicas; de Goldthorpe para estudos socioeconômicos ingleses, adaptado pela Sociedade Espanhola de Epidemiologia; e o modelo de Wright para pesquisa em sociologia e ciência política, também usado em inquéritos populacionais em saúde. Em conclusão, conceitualmente cada um dos modelos apresentados é coerente com a concepção teórica que os embasam, mas não há como optar por qualquer deles, descartando os demais.

  20. Iodo em alimentos consumidos em Portugal

    Coelho, Inês; Delgado, Inês; Costa, Sofia; Castanheira, Isabel; Calhau, Maria Antónia

    2015-01-01

    O iodo é um elemento vestigial essencial na dieta humana e animal, com uma importância nutricional bem estabelecida. É indispensável para a síntese das hormonas da tiroide, tiroxina e triiodotirosina, cujo principal papel está relacionado com o crescimento e desenvolvimento dos órgãos, em particular do cérebro. A fonte natural de iodo são os alimentos. Contudo, de acordo com a OMS um terço da população mundial sofre de algum tipo de carência de iodo. A deficiência crônica de iodo pode levar a...

  1. Prima segnalazione di <em>Brachylaima fulvusem> Dujardin, 1843 (Digenea, Brachylaimidae in <em>Sorex> cfr. <em>antinorii> Bonaparte, 1848 (Insectivora, Soricidae in Italia

    Juan Carlos Casanova

    2003-10-01

    Full Text Available Un?indagine parassitologica è stata condotta su esemplari di <em>Sorex> cfr. <em>antinorii> Bonaparte, 1840 (Insectivora, Soricidae catturati in Sila Grande (Valle Capra; 16.29.30; 39.21.40. Uno degli esemplari è stato trovato parassitato da Trematodi digenei rinvenuti nell?esofago e nello stomaco. I parassiti isolati sono stati fissati con liquido di Bouin, colorati con carminio acetico di Semichon, fissati in una serie di alcooli, chiarificati in xilolo e montati con Balsamo del Canada. I parassiti sono stati identificati come membri della Famiglia Brachylaimidae Joyeux & Foley (1930 appartenenti al genere <em>Brachylaima> Dujardin (1843. La morfologia generale ed i caratteri metrici hanno permesso di identificarli come <em>B. fulvusem> Dujardin, 1843 (lunghezza corpo: 2.39-2.46; larghezza corpo: 0.72-0.78; diametro trasversale ventosa orale: 212.48- 238.08x240.64-266.24; ventosa ventrale: 250.88-258.56x250.88-266.24; faringe 120.32-168.96; testicoli: 151.04-189.44x168.96-189.44; ovario: 122.88x171.52; uova: 26-30x2-17. Il range dei dati morfometrici coincide con quelli riscontrati da diversi autori negli esemplari di <em>B. fulvusem> in Europa centrale e occidentale (Jourdane, 1971; Lewis, 1969; Zarnowski,1960; Mas-Coma & Gallego, 1975. Dopo la descrizione originale, la sistematica di <em>B. fulvusem> Blanchard, 1847 non è stata mai confutata, sebbene varie specie dei generi <em>Harmostomum> Braun, 1899 e <em>Panopistus Sinitzinem>, 1931 siano state proposte come sinonimi di <em>B. fulvusem> da diversi autori. Zarnowski (1960 considera aperta la questione di identità di <em>H. (H. dujardiniem> Baer, 1928 e propone la sinonimia di <em>B. oesophageiem> Shaldibin, 1953 e <em>B. fulvusem>. Lewis (1969, al contrario, ha riconvalidato <em>B. oesophageiem> come specie, utilizzando criteri che, però, Jourdane (1971 ritiene, non idonei a differenziare le due specie. Mas-Coma & Gallego (1975, considerano <em

  2. The EM Earthquake Precursor

    Jones, K. B., II; Saxton, P. T.

    2013-12-01

    Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After the 1989 Loma Prieta Earthquake, American earthquake investigators predetermined magnetometer use and a minimum earthquake magnitude necessary for EM detection. This action was set in motion, due to the extensive damage incurred and public outrage concerning earthquake forecasting; however, the magnetometers employed, grounded or buried, are completely subject to static and electric fields and have yet to correlate to an identifiable precursor. Secondly, there is neither a networked array for finding any epicentral locations, nor have there been any attempts to find even one. This methodology needs dismissal, because it is overly complicated, subject to continuous change, and provides no response time. As for the minimum magnitude threshold, which was set at M5, this is simply higher than what modern technological advances have gained. Detection can now be achieved at approximately M1, which greatly improves forecasting chances. A propagating precursor has now been detected in both the field and laboratory. Field antenna testing conducted outside the NE Texas town of Timpson in February, 2013, detected three strong EM sources along with numerous weaker signals. The antenna had mobility, and observations were noted for recurrence, duration, and frequency response. Next, two

  3. <em>Bacillus anthracisem> Factors for Phagosomal Escape

    Irene Zornetta

    2012-07-01

    Full Text Available The mechanism of phagosome escape by intracellular pathogens is an important step in the infectious cycle. During the establishment of anthrax, <em>Bacillus anthracisem> undergoes a transient intracellular phase in which spores are engulfed by local phagocytes. Spores germinate inside phagosomes and grow to vegetative bacilli, which emerge from their resident intracellular compartments, replicate and eventually exit from the plasma membrane. During germination, <em>B. anthracisem> secretes multiple factors that can help its resistance to the phagocytes. Here the possible role of <em>B. anthracisem> toxins, phospholipases, antioxidant enzymes and capsules in the phagosomal escape and survival, is analyzed and compared with that of factors of other microbial pathogens involved in the same type of process.

  4. On subspecific taxonomy of <em>Microtus saviiem> (Rodentia, Arvicolidae

    Longino Contoli

    2003-10-01

    Full Text Available Riassunto Sulla tassonomia sottospecifica di <em>Microtus saviiem> (Rodentia, Arvicolidae Viene riveduta e riassunta la situazione tassonomica sottospecifica di <em>Microtus (Terricola saviiem>, anche tramite la descrizione di due nuovi taxa: <em>Microtus (Terricola savii tolfetanusem>, dei Monti della Tolfa e <em>Microtus (Terricola savii niethammericusem>, del Gargano.

  5. Ancylostoma duodenale em estrangeiros radicados em Botucatu, SP, Brasil

    Florence F.S. Kerr

    1981-06-01

    Full Text Available Utilizando-se a técnica de Harada & Mori foi efetuada verificação das espécies de Ancylostomidae prevalentes entre imigrantes europeus, asiáticos e brasileiros residentes no município de Botucatu, Estado de São Paulo, Brasil. Ancylostoma duodenale foi encontrado em 8,5% dos imigrantes asiáticos e Necator americanus em 3,5% dos europeus e em 18% dos brasileiros examinados.

  6. How <em>Varroa> Parasitism Affects the Immunological and Nutritional Status of the Honey Bee, <em>Apis melliferaem>

    Katherine A. Aronstein

    2012-06-01

    Full Text Available We investigated the effect of the parasitic mite <em>Varroa destructorem> on the immunological and nutritional condition of honey bees, <em>Apis melliferaem>, from the perspective of the individual bee and the colony. Pupae, newly-emerged adults and foraging adults were sampled from honey bee colonies at one site in S. Texas, USA. <em>Varroa>‑infested bees displayed elevated titer of Deformed Wing Virus (DWV, suggestive of depressed capacity to limit viral replication. Expression of genes coding three anti-microbial peptides (<em>defensin1, abaecin, hymenoptaecinem> was either not significantly different between <em>Varroa>-infested and uninfested bees or was significantly elevated in <em>Varroa>-infested bees, varying with sampling date and bee developmental age. The effect of <em>Varroa> on nutritional indices of the bees was complex, with protein, triglyceride, glycogen and sugar levels strongly influenced by life-stage of the bee and individual colony. Protein content was depressed and free amino acid content elevated in <em>Varroa>-infested pupae, suggesting that protein synthesis, and consequently growth, may be limited in these insects. No simple relationship between the values of nutritional and immune-related indices was observed, and colony-scale effects were indicated by the reduced weight of pupae in colonies with high <em>Varroa> abundance, irrespective of whether the individual pupa bore <em>Varroa>.

  7. Trabalho em equipa

    Antunes, Andreia Sofia Duarte

    2016-01-01

    O presente relatório de estágio tem como tema principal o trabalho em equipa. Aborda com mais pormenor o subtema dos momentos de reflexão na equipa pedagógica. Ao longo do estudo são vários os conceitos abordados e a interligação entre os mesmos. Pretendo dar a conhecer a temática em questão e conceções que lhe estão naturalmente associadas. Sendo um estudo investigativo são abordados os métodos utilizados ao longo de toda a investigação. Com este relatório pretende-se alcançar qual ...

  8. Spatial based Expectation Maximizing (EM)

    Balafar M A

    2011-01-01

    Abstract Background Expectation maximizing (EM) is one of the common approaches for image segmentation. Methods an improvement of the EM algorithm is proposed and its effectiveness for MRI brain image segmentation is investigated. In order to improve EM performance, the proposed algorithms incorporates neighbourhood information into the clustering process. At first, average image is obtained as neighbourhood information and then it is incorporated in clustering process. Also, as an option, us...

  9. Synthesis and Spectroscopic Analysis of Novel 1<em>H-Benzo[d>]imidazoles Phenyl Sulfonylpiperazines

    Amjad M. Qandil

    2012-05-01

    Full Text Available A group of benzimidazole analogs of sildenafil, 3-benzimidazolyl-4-methoxy-phenylsulfonylpiperazines 2–4 and 3-benzimidazolyl-4-methoxy-<em>N,N>-dimethyl- benzenesulfonamide (5, were efficiently synthesized. Compounds 2–5 were characterized by NMR and MS and contrary to the reported mass spectra of sildenafil, the spectra of the piperazine-containing compounds 2–4 showed a novel fragmentation pattern leading to an <em>m/z> = 316. A mechanism for the formation of this fragment was proposed.

  10. Proximate Composition, Nutritional Attributes and Mineral Composition of <em>Peperomia> <em>pellucida> L. (Ketumpangan Air Grown in Malaysia

    Maznah Ismail

    2012-09-01

    Full Text Available This study presents the proximate and mineral composition of <em>Peperomia> <em>pellucida> L., an underexploited weed plant in Malaysia. Proximate analysis was performed using standard AOAC methods and mineral contents were determined using atomic absorption spectrometry. The results indicated <em>Peperomia> <em>pellucida> to be rich in crude protein, carbohydrate and total ash contents. The high amount of total ash (31.22% suggests a high-value mineral composition comprising potassium, calcium and iron as the main elements. The present study inferred that <em>Peperomia> <em>pellucida> would serve as a good source of protein and energy as well as micronutrients in the form of a leafy vegetable for human consumption.

  11. Dinâmica da institucionalização de idosos em Belo Horizonte, Brasil

    Chaimowicz Flávio

    1999-01-01

    Full Text Available OBJETIVO: O processo de envelhecimento populacional brasileiro tem sido acompanhado por transformações epidemiológicas e sociais que, em outros países, aumentaram a demanda por instituições de longa permanência. Nesse sentido, desenvolveu-se estudo sobre dinâmica da institucionalização de idosos através da análise da oferta de leitos e características demográficas dos residentes em asilos. MÉTODOS: Foi realizado levantamento dos asilos de idosos do Município de Belo Horizonte, MG. Foram registradas datas de nascimento e admissão de 1.128 residentes de 33 dos 40 asilos em funcionamento no município. A lotação foi calculada através da capacidade informada e da taxa de institucionalização, segundo dados da Pesquisa Nacional por Amostra de Domicílios (PNAD. RESULTADOS: As taxas de institucionalização de idosos (65+ do município foram 0,9% (mulheres e 0,3% (homens. A lotação mediana dos asilos era de 92%. Dentre os 1.128 residentes arrolados (92,5% do total, as mulheres (81% apresentavam maiores médias de idade (76,4 x 70,4 anos; p=0,00 e estada (5,6 x 4,5 anos; p=0,01. DISCUSSÃO/CONCLUSÕES: Elevada lotação, listas de espera nos asilos filantrópicos (85% do total e rígidos critérios para admissão (metade recusava idosos demenciados ou dependentes sugerem que a baixa taxa de institucionalização se deve à escassez de vagas. A predominância de idosas reflete a prevalência de viúvas ou separadas na comunidade (66% contra 76% de homens casados. A proporção de homens adultos (31% < 65 anos sugere dificuldade de se auto-sustentarem após a viuvez. Elevada taxa de mortalidade (24% durante 20 meses de acompanhamento de amostra aleatória de 263 residentes, incompatível com o rigor dos critérios de admissão, determina a baixa mediana de estada (3 anos. Os dados refletem o anacronismo de um sistema não direcionado à manutenção dos idosos em seus próprios domicílios.

  12. Ultrasound-Assisted Extraction of Syringin from the Bark of <em>Ilex em>rotunda> Thumb Using Response Surface Methodology

    Hui Wang; Li-Chun Zhao; Wei Li; Xin Deng; Xiang-Hua Xia; Jian Liang; Geng-Liang Yang; Ying He

    2012-01-01

    In this work, a rapid extraction method based on ultrasound-assisted extraction (UAE) of syringin from the bark of <em>Ilex rotunda em>Thumb using response surface methodology (RSM) is described. The syringin was analyzed and quantified by high performance liquid chromatography coupled with UV detection (HPLC-UV). The extraction solvent, extraction temperature and extraction time, the three main factors for UAE, were optimized with Box-Behnken design (BBD) to obtain the highest ...

  13. Chemical Composition, Antimicrobial and Antitumor Activities of the Essential Oils and Crude Extracts of<em> Euphorbiaem>> macrorrhizaem>

    Haji Akber Aisa

    2012-05-01

    Full Text Available The present study aimed to examine the chemical composition and biological activity of essential oils extracted from <em>Euphorbia macrorrhizaem> collected from Northwest China. The major constituents of the essential oils of aerial parts and roots of <em>E. macrorrhizaem> are acorenone B (16.72% and 25.80%, (+-cycloisosativene (14.94% and 12.40%, 3a-hydroxy-5b-androstane (10.62% and 5.52%, copaene (7.37% and 6.29%, l-calamenene (4.13% and 4.65% and β-cedrene (8.40% and 7.98%, respectively. The minor components of them are thymene, γ-terpinene, thymecamphor, α-cedrene, zingiberene, trans-caryophyllene, β-chamigrene, curcumene, pentadecane, (−-α-muurolene, cuparene, γ-cadinene, (<em>Z>-3-heptadecene, 1,3,7,7-tetramethyl-2-oxabicyclo(4.4.0dec-5-en-4-one, hexahydrofarnesyl acetone, γ-elixene and palmitinic acid. The antimicrobial and antitumor activitiy of the <em>E. macrorrhizaem> essential oil against <em>Staphyloccocus aureusem>, <em>Escherichia coliem>, <em>Canidia Albicansem> and Caco-2 cells were evaluated. Among all the tested microorganisms and Caco-2 cells, the essential oils showed the strongest inhibitory effect on <em>Staphyloccocus aureus em>(MIC = 2.8 μg/mL and Caco-2 cell (IC50 = 11.86 μg/mL, whereas no effect on <em>Escherichia coliem> and <em>Candida em>albicans>. The data of this study suggested that the <em>E. macrorrhizaem> essential oils have great potential as a natural medicine for microbial infections and cancers.

  14. Effects of <em>Citrus aurantiumem> (Bitter Orange Fruit Extracts and <em>p>-Synephrine on Metabolic Fluxes in the Rat Liver

    Rosane Marina Peralta

    2012-05-01

    Full Text Available The fruit extracts of <em>Citrus aurantiumem> (bitter orange are traditionally used as weight-loss products and as appetite supressants. An important fruit component is <em>p>-synephrine, which is structurally similar to the adrenergic agents. Weight-loss and adrenergic actions are always related to metabolic changes and this work was designed to investigate a possible action of the <em>C. aurantiumem> extract on liver metabolism. The isolated perfused rat liver was used to measure catabolic and anabolic pathways, including oxygen uptake and perfusion pressure. The <em>C. aurantiumem> extract and <em>p>-synephrine increased glycogenolysis, glycolysis, oxygen uptake and perfusion pressure. These changes were partly sensitive to a- and b-adrenergic antagonists. <em>p>-Synephrine (200 mM produced an increase in glucose output that was only 15% smaller than the increment caused by the extract containing 196 mM <em>p>-synephrine. At low concentrations the <em>C. aurantiumem> extract tended to increase gluconeogenesis, but at high concentrations it was inhibitory, opposite to what happened with <em>p>-synephrine. The action of the <em>C. aurantiumem> extract on liver metabolism is similar to the well known actions of adrenergic agents and can be partly attributed to its content in <em>p>-synephrine. Many of these actions are catabolic and compatible with the weight-loss effects usually attributed to <em>C. aurantiumem>.

  15. Antioxidant Profile of <em>Trifolium pratenseem> L.

    Heidy Schwartsova

    2012-09-01

    Full Text Available In order to examine the antioxidant properties of five different extracts of <em>Trifolium pratenseem> L. (Leguminosae leaves, various assays which measure free radical scavenging ability were carried out: 1,1-diphenyl-2-picrylhydrazyl, hydroxyl, superoxide anion and nitric oxide radical scavenger capacity tests and lipid peroxidation assay. In all of the tests, only the H2O and (to some extent the EtOAc extracts showed a potent antioxidant effect compared with BHT and BHA, well-known synthetic antioxidants. In addition, <em>in vivo em>experiments were conducted with antioxidant systems (activities of GSHPx, GSHR, Px, CAT, XOD, GSH content and intensity of LPx in liver homogenate and blood of mice after their treatment with extracts of <em>T. pratenseem> leaves, or in combination with CCl4. Besides, in the extracts examined the total phenolic and flavonoid amounts were also determined, together with presence of the selected flavonoids: quercetin, luteolin, apigenin, naringenin and kaempferol, which were studied using a HPLC-DAD technique. HPLC-DAD analysis showed a noticeable content of natural products according to which the examined <em>Trifolium pratenseem> species could well be regarded as a promising new source of bioactive natural compounds, which can be used both as a food supplement and a remedy.

  16. Casca de soja em dietas para coelhos em crescimento

    Ana Carolina Kohlrausch Klinger

    2015-01-01

    Full Text Available O presente trabalho teve como objetivo avaliar efeitos da inclusão de casca de soja em substituição ao feno de alfafa sobre o desempenho, características da carcaça e trato gastrointestinal e parâmetros bioquímicos de coelhos em fase de crescimento. Foram utilizados 30 coelhos da raça Nova Zelândia Branca, divididos igualmente em três tratamentos, compostos pela dieta experimental padrão (sem inclusão de casca de soja; e pelas dietas com 50% e 100% de substituição de alfafa por casca de soja nas respectivas rações experimentais. Concluiu-se que a casca de soja pode ser incluída em dietas para coelhos em crescimento, em substituição ao feno de alfafa em até 100% sem causar danos no desempenho nas características de carcaça e do trato gastrointestinal e parâmetros bioquímicos dos animais, durante a fase de crescimento. Porém, a utilização deste co-produto exige a necessidade de estudos mais aprofundados em virtude da escassez de dados.

  17. Discussion on Tensile Test Elongation in API SPEC 5L(45th Version)%对API SPEC 5L(45版)中有关拉伸试验伸长率的讨论

    李记科; 杨红兵

    2015-01-01

    In this article, after discussion on tensile test elongation in API SPEC 5L (45th version) 10.2.4 clause, it considered its standard requirements are unreasonable. It suggests to adopt the requirements in the 6.2.1 clause of API SPEC 5L (43rd version):when elongation is recorded or reported, the record or report shall show the nominal width of the test specimen when strip specimens are used and the diameter and gauge length when round bar specimens are used, or shall state when full section specimens are used. Or the standard requirements are modified to:The percentage elongation of 4 times proportion test pieces (gauge length is 4 times the diameter of the round test pieces, L0=4D0, k= L0≈4.5 ) after fracture shall be reported.√S0 For test pieces with reference to a gauge length of 50 mm(2 in), the measured elongation after fracture shall be converted to a percentage elongation of 4 times proportion test pieces in accordance with ISO 2566-1 or ASTM A370.%对API SPEC 5L (45版)10.2.4试验方法中有关拉伸试验伸长率的内容进行了讨论,认为其标准要求不合理。建议采用API SPEC 5L (43版)6.2.1拉伸性能条款中的要求:“当需记录或报告伸长率时,如采用板状试样,记录或报告中应注明试样的公称宽度;如采用圆棒试样,应注明直径和标距长度;如采用全断面试样亦应予以注明”。或者修改为:“应报告4倍比例试样(标距长度为4倍直径的棒状试样, L0=4D0, k= L0√S0≈4.5)的断后伸长率。对于采用50 mm(2 in)定标距试样,应按照ISO 2566-1或ASTM A370,将断裂后测得的伸长率转换为4倍比例试样的断后伸长率。”

  18. A guerra em Pessoa

    Frias, Joana Matos

    2014-01-01

    Leitura e comentário crítico do poema "Os jogadores de xadrez", do heterónimo pessoano Ricardo Reis, com vista a uma proposta de sistematização da natureza da relação que o poeta manteve com os eventos em curso nos anos decisivos da sua formação e consolidação artísticas e literárias. Reading and critical review of the poem "The chess players", by Fernando Pessoaapos;s heteronym Ricardo Reis, aiming to propose a systematization of the kind of relationship the poet has maintained with the o...

  19. Envolvimento parental em creche

    Oliveira, Marta Isabel da Silva e

    2014-01-01

    Dissertação de mestrado em Educação de Infância A família e a creche são os dois primeiros ambientes sociais que proporcionam à criança estímulos e condutas, sendo, consequentemente, instituições fundamentais no seu crescimento. É importante promover uma boa comunicação entre a creche e os pais, incentivando-os a participarem na educação dos seus filhos, demonstrando o quanto é importante para as crianças este seu envolvimento. Cabe, também, aos educadores/profissionais criar c...

  20. Sustentabilidade em Hotelaria

    Almeida, Joana Branquinho Ramos de

    2016-01-01

    A grande ascensão da atividade turística ao longo das últimas décadas é um dos fenómenos económicos, sociais e culturais mais notáveis de todos os tempos. Durante muitos anos os agentes económicos do sector ignoraram os impactos ambientais desta atividade, contudo, o crescimento expressivo que se tem verificado em conjunto com as alterações climáticas, tornaram evidentes algumas sérias ameaças sociais, ambientais e culturais nos destinos turísticos mais vulneráveis. A sustentab...

  1. Frenectomia em foco

    Vieira, Joana Isabel Monteiro de Paiva

    2012-01-01

    O freio é uma estrutura anatómica oral classificada em freio labial (médio maxilar ou mandibular, lateral maxilar ou mandibular) ou lingual que se pode tornar num problema quando a sua inserção cria impedimentos estruturais e dificuldades a vários níveis. Um freio labial anormal pode causar algumas anomalias ou problemas, tais como um diastema interincisal, problemas protéticos, doença periodontal relacionada com a retenção de alimentos, dificuldades na higiene oral e na mobilidade labial. Na...

  2. Laserterapia em Implantologia

    Reis, Rita Silva

    2013-01-01

    A palavra LASER é um acrónimo de “Light Amplification by Simulated Emission of Radiation”, que significa a amplificação da radiação luminosa por um processo de emissão estimulada. Este dispositivo produz radiação eletromagnética com algumas características especiais, que a diferem de outras fontes de radiação luminosa, sendo monocromática, coerente e colimada. A maioria da literatura relacionada com o LASER distingue-o em dois grandes grupos: os de alta intensidade e os de baixa intensidade. ...

  3. Burnout em Cuidadores Formais

    Silva, Juliana Marisa Fernandes

    2016-01-01

    Dissertação apresentada à Universidade Fernando Pessoa como parte dos requisitos para a obtenção do grau de Mestre em Psicologia, ramo de Psicologia Clínica e da Saúde Este estudo é sobre a Síndrome de Burnout e teve como objetivo geral compreender se o Burnout está presente nos cuidadores formais da Santa Casa da Misericórdia de Castelo de Paiva e quais as variáveis socioprofissionais que poderão exercer influência no seu aparecimento. Pretendeu-se avaliar o Burnout dos cuidadores a tr...

  4. <em>Ipomoea aquaticaem> Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity

    Hadi, A. Hamid A.; Siddig Ibrahim Abdelwahab; Suzy Munir Salama; Salim Said Alkiyumi; Mahmood Ameen Abdullah; Ahmed Salim Alrashdi

    2012-01-01

    In the Indian system of traditional medicine (Ayurveda) it is recommended to consume <em>Ipomoea em>aquatica> to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of <em>I. aquaticaem> against liver damage were evaluated in thioacetamide (TAA)-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD) rats were orally fed with <em>...

  5. The Self-assembly Synthesis and Structure of a Novel 1-D Lead Iodide Adduct: [(Pb2I5)(L-H+)· 2DMF]n (L=Piperazine)%一种新颖一维铅碘聚合物[(Pb2I5)(L-H+)·2DMF]n(L=Piperazine)的自组装合成和晶体结构

    李浩宏; 陈之荣; 黄长沧; 赵斌; 肖荣平; 倪朝霞

    2005-01-01

    The lead iodide adduct [(Pb2I5)(L-H+) ·2DMF]n (L=piperazine) has been prepared by self-assembly and structurally characterized. It presents one dimensional structure and crystallizes in Triclinic, P1 space group with the crystal cell parameter: a=0.92206(18) nm, b=1.237 5(3) nm, c=1.297 2(3) nm,α=99.05(3)°, β=102.98(3)°, y=mula C16H43NsO4Pb4I10 and Mr=2 509.39, the final R=0.053 3 and wR=O.146 4 for 3 889 observed reflections with I>2σ(Ⅰ). CCDC: 250760.

  6. O insight em psiquiatria

    Ana Margarida P. Cardoso

    2008-12-01

    Full Text Available O sinal de que algo está a acontecer contribui para que o paciente reconheça que alguma coisa de estranho se está a passar consigo. Este reconhecimento faz com que o sujeito possa desempenhar uma função activa e seja um elemento colaborante do seu processo de recuperação. Cada doença apresenta, contudo, diferentes sintomas, uma vez que cada doença psiquiátrica consiste em diferentes perturbações com diversos efeitos sobre o funcionamento mental. Desta maneira, o fenómeno do insight que é registado em cada doença é diferente e expressa-se sob diferentes formas, não somente devido às manifestações clínicas da doença mas também devido às características individuais do sujeito.

  7. Identificazione di due polimorfismi mitocondriali utili alla discriminazione tra <em>Martes martesem> e <em>Martes foinaem>

    Licia Colli

    2003-10-01

    Full Text Available La famiglia Mustelidae è presente sul territorio italiano con 7 specie autoctone (<em>Meles melesem>, <em>Mustela ermineaem>, <em>M. nivalisem>, <em>M. putoriusem>, <em>Lutra lutraem>, <em>Martes foinaem>, <em>M. martesem> ed una naturalizzata (<em>Mustela visonem>. In tassonomia, variazioni morfologiche e morfometriche, spesso a carattere "locale", possono invalidare i tradizionali metodi di diagnosi utilizzati nell'attribuzione specifica. Inoltre criteri di discriminazione legati a caratteristiche corporee macroscopiche non sono applicabili nel caso in cui si disponga unicamente di resti quali peli, depositi fecali, tracce ematiche ecc. Nell'ambito dei mustelidi sono noti fenomeni di sovrapposizione dei caratteri diagnostici che rendono problematica l'identificazione delle specie, come nel caso di <em>M. martesem> e <em>M. foinaem>. Negli ultimi anni l'identificazione di polimorfismi genetico-molecolari a scopo tassonomico ha permesso di dirimere numerosi casi incerti. In questo lavoro sono presentati i dati preliminari di uno studio volto ad identificare polimorfismi discriminanti le due specie di mustelidi considerate. L'analisi è stata condotta con enzimi di restrizione applicati ad una regione del genoma mitocondriale. Parte della sequenza del gene citocromo b (cyt b è stata amplificata con PCR e <em>primers> universali, ottenendo un frammento di circa 360 bp. Gli enzimi di restrizione impiegati nell'analisi sono stati scelti in accordo con profili di digestione teorici, ricavati con un apposito software a partire da sequenze di cyt b di <em>M. martesem> e <em>M. foinaem> presenti in banche dati. A seguito della digestione sequenziale con gli enzimi Hae III e Bgl I, il profilo elettroforetico generato mostra la presenza di una banda di circa 180 bp negli individui appartenenti alla specie <em>M. martesem> e di due bande distinte di circa 130 e 230 bp negli esemplari di <em>M. foinaem>. Il campione da noi

  8. Corrosion behavior of X-70 pipe steel in near-neutral pH solution

    Niu, L.; Cheng, Y. F.

    2007-08-01

    The mechanism of near-neutral pH stress corrosion cracking (SCC) of natural gas pipelines has not been well-established since the first accident was found in the 1980s. In particular, the role of hydrogen in near-neutral pH SCC has remained unknown. In this work, cyclic voltammetry was used to comprehensively investigate the fundamentals of the electrochemical corrosion reactions occurring at the steel/solution interface in diluted, 5% CO 2/N 2-purged, near-neutral pH bicarbonate solutions. It is shown that there is no stable oxide film formed on the steel surface in near-neutral pH solution. The dissolution-based cracking mechanism does not apply for near-neutral pH SCC of pipelines. The formation of a metastable Fe(OH) 2 deposit layer shows a catalytic activity on hydrogen evolution reaction, indicating that a significant amount of hydrogen could be generated under near-neutral pH condition. The presence of corrosive anions in the soil electrolyte enhances both the anodic polarization of the steel and the cathodic hydrogen evolution reaction, resulting in an increased hydrogen evolution rate. The introduction of oxygen could form a stable oxide film on the surface of steel, resulting in the loss of the surface catalytic effect on hydrogen evolution reaction. Thus, a hydrogen-based mechanism does not apply for SCC in the presence of oxygen.

  9. Comparative Proteomic Analysis of <em>Lactobacillus> <em>plantarum> WCFS1 and Δ<em>ctsR> Mutant Strains Under Physiological and Heat Stress Conditions

    Daniela Fiocco

    2012-08-01

    Full Text Available Among Gram-positive bacteria, CtsR (Class Three Stress gene Repressor mainly regulates the expression of genes encoding the Clp ATPases and the ClpP protease. To gain a better understanding of the biological significance of the CtsR regulon in response to heat-shock conditions, we performed a global proteomic analysis of <em>Lactobacillus> <em>plantarum> WCFS1 and ∆<em>ctsR> mutant strains under optimal or heat stress temperatures. Total protein extracts from bacterial cells were analyzed by two-dimensional gel fractionation. By comparing maps from different culture conditions and different <em>L.> <em>plantarum> strains, image analysis revealed 23 spots with altered levels of expression. The proteomic analysis of <em>L.> <em>plantarum> WCFS1 and <em>ctsR> mutant strains confirms at the translational level the CtsR-mediated regulation of some members of the Clp family, as well as the heat induction of typical stress response genes. Heat activation of the putative CtsR regulon genes at transcriptional and translational levels, in the <em>∆ctsR> mutant, suggests additional regulative mechanisms, as is the case of <em>hsp1em>. Furthermore, isoforms of ClpE with different molecular mass were found, which might contribute to CtsR quality control. Our results could add new outlooks in order to determine the complex biological role of CtsR-mediated stress response in lactic acid bacteria.

  10. Ancylostoma duodenale em estrangeiros radicados em Botucatu, SP, Brasil

    Florence F.S. Kerr; Corrêa, Fernando M. A.

    1981-01-01

    Utilizando-se a técnica de Harada & Mori foi efetuada verificação das espécies de Ancylostomidae prevalentes entre imigrantes europeus, asiáticos e brasileiros residentes no município de Botucatu, Estado de São Paulo, Brasil. Ancylostoma duodenale foi encontrado em 8,5% dos imigrantes asiáticos e Necator americanus em 3,5% dos europeus e em 18% dos brasileiros examinados.A survey of the species of Ancylostomidae causing infection among European inmigrants and Brazilian residents in Botucatu, ...

  11. Short and Long-Term Effects of <em>Baccharis articulataem> on Glucose Homeostasis

    Flávio H. Reginatto

    2012-06-01

    Full Text Available In this study, the<em> in vivoem> effect of the crude extract and <em>n>-butanol and aqueous residual fractions of <em>Baccharis articulataem> (Lam. Pers. on serum glucose levels, insulin secretion and liver and muscle glycogen content, as well as<em> in vitroem> action on serum intestinal disaccharidase activity and albumin glycation were investigated. Oral administration of the extract and fractions reduced glycemia in hyperglycemic rats. Additionally, the <em>n>-butanol fraction, which has high flavonoids content, stimulated insulin secretion, exhibiting an insulinogenic index similar to that of glipizide. Also, the <em>n>-butanol fraction treatment significantly increased glycogen content in both liver and muscle tissue. <em>In vitroem> incubation with the crude extract and <em>n>-butanol and aqueous residual fractions inhibited maltase activity and the formation of advanced glycation end-products (AGEs. Thus, the results demonstrated that <em>B. articulataem> exhibits a significant antihyperglycemic and insulin-secretagogue role. These effects on the regulation of glucose homeostasis observed for <em>B. articulataem> indicate potential anti-diabetic properties.

  12. Osteoporose em caprinos

    Fábio B. Rosa

    2013-04-01

    Full Text Available Foi realizado um estudo de casos de osteoporose em caprinos provenientes de uma propriedade na área de abrangência do LPV-UFSM, determinando a epidemiologia, o quadro clínico-patológico e discutindo os prováveis mecanismos patogenéticos. Cinco cabras, fêmeas, SRD, de seis meses a seis anos de idade foram afetadas. As cabras eram mantidas em campo nativo, sem suplementação com ração e sob superlotação. Os principais sinais clínicos foram emagrecimento, dificuldade de locomoção e permanência em decúbito por longos períodos. As principais alterações macroscópicas nos ossos examinados foram vistas nas superfícies de corte e caracterizavam-se por depleção do osso esponjoso (porosidade e redução acentuada da espessura do osso cortical. Havia também marcada atrofia serosa da gordura da medula óssea. Microscopicamente, nas regiões avaliadas (úmero proximal, rádio distal, fêmur distal, tíbia proximal e corpos das vértebras lombares foi observada redução moderada a acentuada do número e da espessura das trabéculas ósseas nas epífises e metáfises dos ossos longos e nos corpos vertebrais. Os achados clínico-patológicos indicaram que a osteoporose observada provavelmente foi causada pela desnutrição. As alterações ósseas (diminuição no número e na espessura das trabéculas do osso esponjoso sugerem que ambos os mecanismos, má formação óssea e reabsorção óssea aumentada, contribuíram para a ocorrência de osteoporose nos caprinos deste estudo.

  13. Synthesis of 1,2,3-Triazole Derivatives and <em>in Vitroem> Antifungal Evaluation on <em>Candida> Strains

    Almir G. Wanderley

    2012-05-01

    Full Text Available 1,2,3-Triazoles have been extensively studied as compounds possessing important biological activities. In this work, we describe the synthesis of ten 2-(1-aryl-1<em>H>-1,2,3-triazol-4-ylpropan-2-ols via copper catalyzed azide alkyne cycloaddition (CuAAc or <em>click chemistryem>. Next the<em> in vitroem> antifungal activity of these ten compounds was evaluated using the microdilution broth method against 42 isolates of four different <em>Candida> species. Among all tested compounds, the halogen substituted triazole 2-[1-(4-chlorophenyl-1<em>H>-(1,2,3triazol-4-yl]propan-2-ol, revealed the best antifungal profile, showing that further modifications could be done in the structure to obtain a better drug candidate in the future.

  14. Em favor da talassografia

    Jean-Louis Boudou

    2001-01-01

    Full Text Available A Talassografia (“descrição do mar” interessa-sepelos impactos físicos, biológicos, ecológicos... culturais da violenta antropização dos ambientes costeiros (oceânicos e continentais, caracterizados pelaexigüidade, vulnerabilidade, fragilidade e plasticidade. Como o Brasil é um “país marítimo”, os geó-grafos (os talassógrafos brasileiros são convidadosa intensificar suas pesquisas nas áreas costeiras e acriar novas estruturas para divulgá-las: Revista, Encontros, Associação, Pós-Graduação... tudo em prolda talassografia.

  15. Antioxidant Profile of <em>Trifolium pratenseem> L.

    Heidy Schwartsova; Mirjana Vojinovic-Miloradov; Sanja Vlaisavljevic; Mira Popovic; Biljana Kaurinovic

    2012-01-01

    In order to examine the antioxidant properties of five different extracts of <em>Trifolium pratenseem> L. (Leguminosae) leaves, various assays which measure free radical scavenging ability were carried out: 1,1-diphenyl-2-picrylhydrazyl, hydroxyl, superoxide anion and nitric oxide radical scavenger capacity tests and lipid peroxidation assay. In all of the tests, only the H2O and (to some extent) the EtOAc extracts showed a potent antioxidant effect compar...

  16. A Great Barrier Reef <em>Sinularia> sp. Yields Two New Cytotoxic Diterpenes

    Cherie A. Motti

    2012-07-01

    Full Text Available The methanol extract of a <em>Sinularia em>sp., collected from Bowden Reef, Queensland, Australia, yielded ten natural products. These included the new nitrogenous diterpene (4<em>R>*,5<em>R>*,9<em>S>*,10<em>R>*,11<em>Z>-4-methoxy-9-((dimethylamino-methyl-12,15-epoxy-11(13-en-decahydronaphthalen-16-ol (1, and the new lobane, (1<em>R*>,2<em>R*>,4<em>S*>,15<em>E>-loba-8,10,13(14,15(16-tetraen-17,18-diol-17-acetate (2. Also isolated were two known cembranes, sarcophytol-B and (1<em>E>,3<em>E>,7<em>E>-11,12-epoxycembratrien-15-ol, and six known lobanes, loba-8,10,13(15-triene-16,17,18-triol, 14,18-epoxyloba-8,10,13(15-trien-17-ol, lobatrientriol, lobatrienolide, 14,17-epoxyloba-8,10,13(15-trien-18-ol-18-acetate and (17<em>R>-loba-8,10,13(15-trien-17,18-diol. Structures of the new compounds were elucidated through interpretation of spectra obtained after extensive NMR and MS investigations and comparison with literature values. The tumour cell growth inhibition potential of 1 and 2 along with loba-8,10,13(15-triene-16,17,18-triol, 14,17-epoxyloba-8,10,13(15-trien-18-ol-18-acetate, lobatrienolide, (1<em>E>,3<em>E>,7<em>E>-11,12-epoxycembratrien-15-ol and sarcophytol-B were assessed against three human tumour cell lines (SF-268, MCF-7 and H460. The lobanes and cembranes tested demonstrated 50% growth inhibition in the range 6.8–18.5 µM, with no selectivity, whilst 1 was less active (GI50 70–175 µM.

  17. Regional Suppression of <em>Bactrocera> Fruit Flies (Diptera: Tephritidae in the Pacific through Biological Control and Prospects for Future Introductions into Other Areas of the World

    Roger I. Vargas

    2012-08-01

    Full Text Available <em>Bactrocera> fruit fly species are economically important throughout the Pacific. The USDA, ARS U.S. Pacific Basin Agricultural Research Center has been a world leader in promoting biological control of <em>Bactrocera> spp. that includes classical, augmentative, conservation and IPM approaches. In Hawaii, establishment of <em>Bactrocera> <em>cucurbitae> (Coquillett in 1895 resulted in the introduction of the most successful parasitoid, <em>Psyttalia> <em>fletcheri> (Silvestri; similarly, establishment of <em>Bactrocera> <em>dorsalis> (Hendel in 1945 resulted in the introduction of 32 natural enemies of which <em>Fopius> <em>arisanus> (Sonan, <em>Diachasmimorpha> <em>longicaudata> (Ashmead and <em>Fopius> <em>vandenboschi> (Fullaway were most successful. Hawaii has also been a source of parasitoids for fruit fly control throughout the Pacific region including Australia, Pacific Island Nations, Central and South America, not only for <em>Bactrocera> spp. but also for <em>Ceratitis> and <em>Anastrepha> spp. Most recently, in 2002, <em>F.> <em>arisanus> was introduced into French Polynesia where <em>B.> <em>dorsalis> had invaded in 1996. Establishment of <em>D.> <em>longicaudata> into the new world has been important to augmentative biological control releases against <em>Anastrepha> spp. With the rapid expansion of airline travel and global trade there has been an alarming spread of <em>Bactrocera> spp. into new areas of the world (<em>i.e.>, South America and Africa. Results of studies in Hawaii and French Polynesia, support parasitoid introductions into South America and Africa, where <em>B.> <em>carambolae> and <em>B.> <em>invadens>, respectively, have become established. In addition, <em>P.> <em>fletcheri> is a candidate for biological control of <em>B.> <em>cucurbitae> in Africa. We review past and more

  18. Extraction of Dihydroquercetin<em> em>from <em>Larix gmeliniem>i> em>with Ultrasound-Assisted and Microwave-Assisted Alternant Digestion

    Yuangang Zu

    2012-07-01

    Full Text Available An ultrasound and microwave assisted alternant extraction method (UMAE was applied for extracting dihydroquercetin (DHQ from <em>Larix gmeliniem>i> wood. This investigation was conducted using 60% ethanol as solvent, 1:12 solid to liquid ratio, and 3 h soaking time. The optimum treatment time was ultrasound 40 min, microwave 20 min, respectively, and the extraction was performed once. Under the optimized conditions, satisfactory extraction yield of the target analyte was obtained. Relative to ultrasound-assisted or microwave-assisted method, the proposed approach provides higher extraction yield. The effect of DHQ of different concentrations and synthetic antioxidants on oxidative stability in soy bean oil stored for 20 days at different temperatures (25 °C and 60 °C was compared. DHQ was more effective in restraining soy bean oil oxidation, and a dose-response relationship was observed. The antioxidant activity of DHQ was a little stronger than that of BHA and BHT. Soy bean oil supplemented with 0.08 mg/g DHQ exhibited favorable antioxidant effects and is preferable for effectively avoiding oxidation. The <em>L. gmeliniiem> wood samples before and after extraction were characterized by scanning electron microscopy. The results showed that the UMAE method is a simple and efficient technique for sample preparation.

  19. Molluscicidal Activity of Methomyl and Cardenolide Extracts from <em>Calotropis proceraem> and <em>Adenium> <em>arabicum> Against the Land Snail <em>Monacha cantianaem>

    Alaa Bayoumi

    2012-05-01

    Full Text Available In this work, we have evaluated the molluscicidal activity of two cardenolide extracts from <em>Adenium arabicumem> Balf f. [the benzene (B and methanol (M extracts], one cardenolide extract from <em>Calotropis proceraem> (Aiton W.T. Aiton (extract C, and methomyl against the harmful land snail <em>Monacha cantianaem> (Montagu. The contact LD50 values for the above mentioned plant extracts were 12.62, 34.63, and 34.35 mg·kg−1 of body weight, respectively, while the LD50 for methomyl was 116.62 mg·kg−1, that is, the plant extracts were 9.24, 3.37, and 3.4 times more toxic than methomyl. In addition, a simple colorimetric method, based on Kedde reagent, was modified to determine cardenolide concentrations in plant extracts. Thin layer chromatography analysis (TLC showed several cardiac glycosidal compounds in each plant extract. The results proved that cardiac glycosides are promising candidate compounds that could be used to control land snails, or exploited to develop new, effective, and environmentally friendly molluscicides.

  20. Discussion about Several Problems on Evaluating X-ray Image According to API SPEC 5L%API SPEC 5L标准射线底片评定过程中的几个问题的探讨

    王晨; 侯永高; 张道峰; 闻康

    2007-01-01

    @@ 随着西气东输等长输管线的建立,我国又迎来了一个管线建设的新的高峰.钢管生产检测在国内无损检测所占比例逐渐加大.钢管厂常年使用的标准主要是GB 9711.1-1997、GB 9711.2-1999和API SPEC 5L.在API SPEC 5L标准的具体使用过程中,由于美国标准体系和工作惯例与我国在其它领域采用的射线检测存在一些不同,造成对标准底片评定的理解存在一定的模糊,下面将在常年使用API SPEC 5L标准的经验中发现的一些问题提出来,供同行参考和斧正.

  1. DESGASTE POR ABRASIÓN DEL ACERO API 5L X65 REVESTIDO CON NIOBIO POR ASPERSIÓN TÉRMICA A PLASMA Y CON INCONEL 625 POR SOLDADURA

    JOSE MATOS

    2012-01-01

    Full Text Available El objetivo de este trabajo fue evaluar y caracterizar el comportamiento mecánico en desgaste del acero API 5L X65, revestido con niobio en comparación al desempeño del revestimiento de la aleación de inconel 625 empleados en la industria de petróleo y gas. El revestimiento de niobio fue obtenido por el proceso de aspersión térmica a plasma de arco no transferido y el revestimiento inconel 625 por soldadura con electrodo revestido. La resistencia al desgaste por abrasión fue evaluada según la norma Petrobras N-2568, en un tribómetro CTER, la rugosidad y el volumen de material desgastado se determinó a través de perfilometría y la dureza de los revestimientos por microscopia Vickers. Los revestimientos obtenidos fueron caracterizados respecto a su morfología por microscopia electrónica de barrido (MEB y microscopía óptica (MO. La mayor dureza del revestimiento con niobio obtenido puede haber contribuido a reducir la tasa de desgaste en comparación con el revestimiento de inconel 625.

  2. Avaliação da microestrutura e propriedades mecânicas de metais de solda obtidos por processos de soldagem manual e automatizado utilizado na soldagem de aço API 5L X80 Evaluation of microstructure and mechanical properties of weld metals obtained by manual and automated welding process used in the welding of API 5L X80 steel

    Siderley Fernandes Albuquerque

    2011-12-01

    Full Text Available O objetivo do trabalho foi avaliar as características da zona termicamente afetada (ZTA e a microestrutura e propriedades mecânicas de metais de solda de juntas soldadas do aço API 5L X80, obtidos para quatro diferentes procedimentos de soldagem utilizando processos manuais e automatizados. Para isto, chapas do referido aço foram soldadas por processo manual ao Arco Elétrico com Eletrodo Revestido (SMAW, utilizando 473 e 673 K como temperaturas de interpasses e o eletrodo celulósico AWS E8010-G como consumível; por processo ao Arco Elétrico com Arame Tubular (FCAW robotizado, utilizando o arame AWS E71T- 1C como metal de adição e argônio com 25%CO2 como gás de proteção; por processo a Arco Elétrico com Eletrodo de Tungstênio (GTAW mecanizado na raiz da solda, usando o arame ER70S-3 e argônio como gás de proteção. As análises microestruturais foram relacionadas com os resultados de ensaios de impacto Charpy nos metais de solda e com os perfis de microdureza Vickers ao longo da junta soldada. Os resultados indicaram maiores percentuais de Ferrita Acicular e maiores valores de resistência ao impacto nos metais de solda e uma menor extensão e granulometria da ZTA, associado ao procedimento de soldagem utilizando processo automatizado com maior velocidade de soldagem.The objective of this work was to evaluate the heat affected zone characteristics and weld metals microstructure and mechanical properties of API 5L X80 steel welded joints, obtained for four different welding procedures using manual and automated processes. For this, plates of this steel were welded by manual Shielded Metal Arc Welding (SMAW process with interpasses temperatures of 473 e 673 K, and using AWS E8010-G electrode as filler metals; robotized Flux Cored Arc Welding (FCAW process, using AWS E71T-1C wire and Ar25%CO2 as consumable and mechanized Gas Tungsten Arc Welding (GTAW process, for the root pass using AWS ER70S-3 and Ar as consumable .The

  3. Antioxidative Properties of Crude Polysaccharides from <em>Inonotus obliquusem>

    Jinyou Duan; Guoting Cui; Wuxia Zhang; Haibo Mu; Amin Zhang; Shunchun Wang

    2012-01-01

    The mushroom <em>Inonotus obliquusem>> em>has been widely used as a folk medicine in Russia, Poland and most of the Baltic countries. In this study, water-soluble and alkali-soluble crude polysaccharides (IOW and IOA) were isolated from <em>I. obliquusem>, and the carbohydrate-rich fractions IOW-1 and IOA-1 were obtained respectively after deproteination and depigmentation. Their contents, such as neutral carbohydrate, uronic acid and protein, were...

  4. Antioxidant Activity of Various Parts of <em>Cinnamomum> cassiaem> Extracted with Different Extraction Methods

    Li-Yeh Chuang

    2012-06-01

    Full Text Available The aim of this study was to investigate the antioxidant activities of various parts (barks, buds, and leaves of <em>Cinnamomum cassia em>extracted with ethanol and supercritical fluid extraction (SFE. For the antioxidant activity comparison, IC50 values of the SFE and ethanol extracts in the DPPH scavenging assay were 0.562–10.090 mg/mL and 0.072–0.208 mg/mL, and the Trolox equivalent antioxidant capacity (TEAC values were 6.789–58.335 mmole Trolox/g and 133.039–335.779 mmole Trolox/g, respectively. In addition, the total flavonoid contents were 0.031–1.916 g/ 100 g dry weight of materials (DW and 2.030–3.348 g/ 100 g DW, and the total phenolic contents were 0.151–2.018 g/ 100 g DW and 6.313–9.534 g/ 100 g DW in the SFE and ethanol extracts, respectively. Based on the results, the ethanol extracts of <em>Cinnamon> barks have potential value as an antioxidant substitute and this study also provide a better technique to extract the natural antioxidant substances from <em>C. cassiaem>.

  5. Activity-Guided Isolation of Antioxidant Compounds from <em>Rhizophora apiculataem>

    Hongbin Xiao

    2012-09-01

    Full Text Available <em>Rhizophora apiculataem> (<em>R. apiculataem> contains an abundance of biologically active compounds due its special salt-tolerant living surroundings. In this study, the total phenolic content and antioxidant activities of various extract and fractions of stem of <em>R. apiculataem> were investigated. Results indicated that butanol fraction possesses the highest total phenolic content (181.84 mg/g GAE/g dry extract with strongest antioxidant abilities. Following <em>in vitroem> antioxidant activity-guided phytochemical separation procedures, lyoniresinol-3α-<em>O>-β-arabinopyranoside (1, lyoniresinol-3α-<em>O>-β-rhamnoside (2, and afzelechin-3-<em>O>-L-rhamno-pyranoside (3 were separated from the butanol fraction. These compounds showed more noticeable antioxidant activity than a BHT standard in the DPPH, ABTS and hydroxyl radical scavenging assays. HPLC analysis results showed that among different plant parts, the highest content of 13 was located in the bark (0.068%, 0.066% and 0.011%, respectively. The results imply that the <em>R. apiculataem> might be a potential source of natural antioxidants and 13 are antioxidant ingredients in <em>R. apiculataem>.

  6. Effects of Cyanobacterial Lipopolysaccharides from <em>Microcystis em>on Glutathione-Based Detoxification Pathways in the Zebrafish (<em>Danio rerioem> Embryo

    John P. Berry

    2012-05-01

    Full Text Available Cyanobacteria (“blue-green algae” are recognized producers of a diverse array of toxic secondary metabolites. Of these, the lipopolysaccharides (LPS, produced by all cyanobacteria, remain to be well investigated. In the current study, we specifically employed the zebrafish (<em>Danio rerioem> embryo to investigate the effects of LPS from geographically diverse strains of the widespread cyanobacterial genus, <em>Microcystis>, on several detoxifying enzymes/pathways, including glutathione-S-transferase (GST, glutathione peroxidase (GPx/glutathione reductase (GR, superoxide dismutase (SOD, and catalase (CAT, and compared observed effects to those of heterotrophic bacterial (<em>i.e.>, <em>E. coliem> LPS. In agreement with previous studies, cyanobacterial<em> em>LPS significantly reduced GST in embryos exposed to LPS in all treatments. In contrast, GPx moderately increased in embryos exposed to LPS, with no effect on reciprocal GR activity. Interestingly, total glutathione levels were elevated in embryos exposed to <em>Microcystis> LPS, but the relative levels of reduced and oxidized glutathione (<em>i.e.>, GSH/GSSG were, likewise, elevated suggesting that oxidative stress is not involved in the observed effects as typical of heterotrophic bacterial LPS in mammalian systems. In further support of this, no effect was observed with respect to CAT or SOD activity. These findings demonstrate that <em>Microcystis> LPS affects glutathione-based detoxification pathways in the zebrafish embryo, and more generally, that this model is well suited for investigating the apparent toxicophore of cyanobacterial LPS, including possible differences in structure-activity relationships between heterotrophic and cyanobacterial LPS, and teleost fish <em>versus> mammalian systems.

  7. On the taxonomy and distribution of <em>Crocidura cossyrensisem> and <em>Crocidura russulaem> (Insectivora, Soricidae in Maghreb

    Longino Contoli

    2001-09-01

    Full Text Available Abstract The paper examines the taxonomic status of North African <em>Crocidura russula Auctorumem>. On the basis of morphological data, the taxon needs to be divided into at least two species: <em>C. russulaem> (Hermann, 1780 from western Europe, coastal Morocco and middle-western Algeria, up to about the Algiers area, and possibly even Sardinia and Ibiza, and another species, distributed in coastal middle-eastern Algeria, Tunisia, Pantelleria and, possibly, La Galite archipelago. The first and only available name for the above, eastern taxon is <em>Crocidura cossyrensisem> Contoli, 1989.

  8. Prima segnalazione di <em>Brachylaima fulvusem> Dujardin, 1843 (Digenea, Brachylaimidae) in <em>Sorex> cfr. <em>antinorii> Bonaparte, 1848 (Insectivora, Soricidae) in Italia

    Juan Carlos Casanova; Concetta Milazzo; Gaetano Aloise; Mara Cagnin; Alexis Ribas

    2003-01-01

    Un?indagine parassitologica è stata condotta su esemplari di <em>Sorex> cfr. <em>antinorii> Bonaparte, 1840 (Insectivora, Soricidae) catturati in Sila Grande (Valle Capra; 16.29.30; 39.21.40). Uno degli esemplari è stato trovato parassitato da Trematodi digenei rinvenuti nell?esofago e nello stomaco. I parassiti isolati sono stati fissati con liquido di Bouin, colorati con carminio acetico di Semichon, fissati in una serie di alcooli, chiarificati in xilolo e m...

  9. Functional Expression in <em>Esc>herichia coliem> of the Disulfide-Rich Sea Anemone Peptide APETx2, a Potent Blocker of Acid-Sensing Ion Channel 3

    Glenn F. King

    2012-07-01

    Full Text Available Acid-sensing ion channels (ASICs are proton-gated sodium channels present in the central and peripheral nervous system of chordates. ASIC3 is highly expressed in sensory neurons and plays an important role in inflammatory and ischemic pain. Thus, specific inhibitors of ASIC3 have the potential to be developed as novel analgesics. APETx2, isolated from the sea anemone <em>Anthopleura elegantissimaem>,> em>is the most potent and selective inhibitor of ASIC3-containing channels<em>.> However, the mechanism of action of APETx2 and the molecular basis for its interaction with ASIC3 is not known. In order to assist in characterizing the ASIC3-APETx2 interaction, we developed an efficient and cost-effective <em>Escherichia coliem> periplasmic expression system for the production of APETx2. NMR studies on uniformly 13C/15N-labelled APETx2 produced in <em>E. coliem> showed that the recombinant peptide adopts the native conformation. Recombinant APETx2 is equipotent with synthetic APETx2 at inhibiting ASIC3 channels expressed in <em>Xenopus> oocytes. Using this system we mutated Phe15 to Ala, which caused a profound loss of APETx2’s activity on ASIC3. These findings suggest that this expression system can be used to produce mutant versions of APETx2 in order to facilitate structure-activity relationship studies.

  10. Adaptabilidade e estabilidade em aveia em ambientes estratificados

    Bertan Ivandro; Silva Giovani Olegário da; Valério Igor Pires; Floss Elmar Luíz; Lorencetti Claudir; Vieira Eduardo Alano; Coimbra Jefferson Luís Meireles; Carvalho Fernando Irajá Félix de; Oliveira Antônio Costa de; Benin Giovani

    2005-01-01

    Vinte cultivares de aveia (Avena sativa L.) foram avaliados para rendimento de grãos nas safras agrícolas de 2001 e 2002 em nove locais dos estados do Paraná, Rio Grande do Sul e São Paulo, com o objetivo de avaliar as estimativas dos componentes de adaptabilidade e estabilidade do rendimento de grãos em ambientes favoráveis e desfavoráveis em presença e ausência de aplicação de fungicida. Foi empregada a metodologia de EBERHART & RUSSELL (1966). A presença de significância para anos, genótip...

  11. Casca de soja em dietas para coelhos em crescimento

    Ana Carolina Kohlrausch Klinger; Geni Salete Pinto de Toledo; Daniel Prois Eggers; Alexandra Pretto; Michael Chimainski; Leila Picolli da Silva

    2015-01-01

    O presente trabalho teve como objetivo avaliar efeitos da inclusão de casca de soja em substituição ao feno de alfafa sobre o desempenho, características da carcaça e trato gastrointestinal e parâmetros bioquímicos de coelhos em fase de crescimento. Foram utilizados 30 coelhos da raça Nova Zelândia Branca, divididos igualmente em três tratamentos, compostos pela dieta experimental padrão (sem inclusão de casca de soja); e pelas dietas com 50% e 100% de substituição de alfafa por casca de soja...

  12. Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine <em>Ostreae em>concha>

    Hong-Bing Liu

    2012-05-01

    Full Text Available To compare the chemical differences between the medicinal and<em> em>cultured oyster shells, their chemical profiles were investigated. Using the ultra performance liquid chromatography-electron spraying ionization-mass spectrometry (UPLC-ESI-MS, combined with principal component analysis (PCA and orthogonal projection to latent structures discriminant analysis (OPLS-DA, the discrimination of the chemical characteristics among the medicinal and cultured oyster shells was established. Moreover, the chemometric analysis revealed some potential key compounds. After a large-scale extraction and isolation, one target key compound was unambiguously identified as caffeine (1 based on extensive spectroscopic data analysis (1D and 2D NMR, MS, and UV and comparison with literature data.

  13. PESQUISA EM DIFICULDADES DE COMPREENSÃO EM LEITURA

    Lucilene Bender de Sousa

    2013-01-01

    Full Text Available Neste artigo revisamos importantes pesquisas sobre as dificuldades de compreensão em leitura. Inicialmente, apresentamos a identificação e classificação das dificuldades já mapeadas. Em seguida, mostramos as contribuições de pesquisas experimentais que investigaram habilidades de baixo nível cognitivo e habilidades de alto nível cognitivo envolvidas na compreensão leitora. Por fim, avaliamos as duas tendências de estudos apresentadas e as necessidades brasileiras no que tange a pesquisa e o ensino da leitura.

  14. Low Diversity Bacterial Community and the Trapping Activity of Metabolites from Cultivable Bacteria Species in the Female Reproductive System of the Oriental Fruit Fly, <em>Bactrocera dorsalisem> Hendel (Diptera: Tephritidae

    Hongyu Zhang

    2012-05-01

    Full Text Available Our goal was to identify the bacteria inhabiting the reproductive system of the female oriental fruit fly, <em>Bactrocera dorsalisem> (Hendel, and evaluate the chemotaxis of <em>B>. <em>dorsalis> to the metabolites produced by the bacteria. Based on 16S rRNA-based polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE, 18 operational taxonomic units (OTUs were assigned to the five bacterial classes <em>Betaproteobacteria>, <em>Alphaproteobacteria>, <em>Gammaproteobacteria>, <em>Bacilli> and <em>Actinobacteria>. Nine OTUs were assigned to <em>Gammaproteobacteria>, which was the most highly represented class. <em>Enterobacteriaceae> constituted the dominant family, and within this family, three genera and five species were identified, including <em>Enterobacter sakazakiiem>, <em>Klebsiella> <em>oxytoca>, <em>Klebsiella> <em>pneumoniae,> Raoultellaem> <em>terrigena em>and <em>Enterobacter> <em>amnigenus>. In this set, the first two species were the dominant components, and the latter three species were the minor ones. Finally, we found that the metabolites produced by <em>R.> terrigenaem>, <em>K. oxytocaem> and <em>K.> pneumoniae em>were attractive to the <em>B.> dorsalisem> adults, and in field studies, <em>B.> dorsalisem> adults were most attracted to <em>K.> oxytocaem>. Collectively, our results suggest that the female reproductive system plays an important role in the transfer of enterobacteria from the gut to fruit. Our data may prompt the development of a female-targeted population control strategy for this fly.

  15. Isolation and Characterization of Microsatellite Markers for <em>Passiflora contractaem>

    Loreta B. Freitas

    2012-09-01

    Full Text Available <em>Passiflora contractaem> Vitta (Passifloraceae is an endemic species of the Atlantic Rainforest, one of the most species-rich ecoregions in the world, although extremely endangered. We have developed an enriched microsatellite library in order to fine-scale studies of the genetic structure<em> em>of> P. contractaem>. Twelve pairs of microsatellite primers were designed, and seven loci were successfully amplified and characterized by genotyping two wild populations of <em>P. contractaem>. All seven loci were polymorphic, with an average number of alleles found being 4.8 and 5 per population. The cross-species transferability was tested using sister species <em>Passiflora ovalisem>> em>Vell. Ex Roemer<em>. em>The development of these markers will contribute to the studies of population genetics in <em>P. contractaem> as well as future studies concerning diversity patterns in the Atlantic Rainforest, and may also help to establish strategies for the conservation of this species.

  16. Thermal Studies of Zn(II, Cd(II and Hg(II Complexes of Some <em>N-Alkyl-N>-Phenyl-Dithiocarbamates

    Peter A. Ajibade

    2012-07-01

    Full Text Available The thermal decomposition of Zn(II, Cd(II and Hg(II complexes of <em>N-ethyl-N>-phenyl and <em>N-butyl-N>-phenyl dithiocarbamates have been studied using thermogravimetric analysis (TGA and differential scanning calorimetry (DSC. The products of the decomposition, at two different temperatures, were further characterized by scanning electron microscopy (SEM and energy-dispersive X-ray spectroscopy (EDX. The results show that while the zinc and cadmium complexes undergo decomposition to form metal sulphides, and further undergo oxidation forming metal oxides as final products, the mercury complexes gave unstable volatiles as the final product.

  17. Rural Emergency Medical Services (EMS) and Trauma

    ... View more Rural Emergency Medical Services (EMS) and Trauma Emergency medical services (EMS) providers care for individuals ... hospital be part of the regional and statewide trauma system? Yes. According to Safety in Numbers: Are ...

  18. Densità di Lepre (<em>Lepus europaeusem>) e Silvilago (<em>Sylvilagus floridanusem>) in ambienti planiziali

    Sandro Bertolino; Perrone, A.; Laura Gola

    2003-01-01

    Il silvilago (<em>Sylvilagus floridanusem>) è un leporide d?origine nordamericana, introdotto in Italia a partire dal 1966 a scopo venatorio. Attualmente la specie è diffusa soprattutto in Piemonte e nella parte occidentale della Lombardia. Il silvilago potrebbe interferire con l?autoctona lepre comune (<em>Lepus europaeusem>), anche se i dati al riguardo sono limitati. Nell?autunno-inverno 2002-2003 abbiamo condotto dei censimenti notturni con faro in alcune aree ...

  19. On the taxonomy and distribution of <em>Crocidura cossyrensisem> and <em>Crocidura russulaem> (Insectivora, Soricidae) in Maghreb

    Longino Contoli; Gaetano Aloise

    2001-01-01

    Abstract The paper examines the taxonomic status of North African <em>Crocidura russula Auctorumem>. On the basis of morphological data, the taxon needs to be divided into at least two species: <em>C. russulaem> (Hermann, 1780) from western Europe, coastal Morocco and middle-western Algeria, up to about the Algiers area, and possibly even Sardinia and Ibiza, and another species, distributed in coastal middle-eastern Algeria, Tunisia, P...

  20. Do sentimento em Florbela Espanca

    Pereira, Custódia de Jesus Gonçalves

    2005-01-01

    The thesis Do Sentimento em Florbela Espanca presents as its main object of study the feelings and emotions displayed in the works of Florbela Espanca, Livro de Mágoas, Livro de Soror Saudade and Charneca em Flor. This theme is then consolidated in four subthemes, which are – Florbela, the Woman, Social and Cultural Framings, the Canon-Law and the Course Books. Thus, we have Florbela Espanca portrayed as an ordinary woman, with her obscure birth, her personal and academic progress. I...

  1. Pobreza e desigualdade em Portugal

    Sabença, Cindy Sofia dos Santos Alves Ribeiro

    2012-01-01

    A conjuntura económica atual levanta questões sobre a condição de vida e bem-estar da sociedade, obrigando a uma reflexão aprofundada sobre a Pobreza e Desigualdade em Portugal. Este estudo tem como objetivo caracterizar a situação portuguesa e apresentar quais os determinantes da Pobreza em Portugal. Para tal é utilizada a base de dados estatísticos do Eurostat não só para a caracterização da sociedade portuguesa num contexto europeu, como também para desenvolver um modelo de estimação linea...

  2. Procedimentos substantivos em auditoria financeira

    Santos, Ana Sofia Pires dos

    2014-01-01

    O presente relatório visa a conclusão do mestrado em Auditoria e Análise Financeira, cujo tema é Auditoria Financeira e procura apresentar as tarefas desenvolvidas por mim, durante o estágio curricular, enquanto assistente de auditoria na empresa Rosa Lopes Gonçalves Mendes & Associados, SROC, Lda., no Entroncamento durante 22 semanas. O relatório é composto por quatro capítulos em que nos primeiros três capítulos faço uma abordagem teórica geral à auditoria financeira, cujo objetivo é a i...

  3. Anorexia e bulimia em odontopediatria

    Bezerra, Fernanda Barros

    2015-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária Introdução: A procura de um ideal de beleza e a obsessão pela estética imposta pela sociedade moderna em que se vive têm promovido o aumento do número de pessoas com transtornos alimentares, como por exemplo, a anorexia nervosa e a bulimia nervosa. Esses transtornos contribuem para o aumento de pacientes com prejuízos, diretos e indi...

  4. Factores de risco em implantologia

    Sousa, Inês Nunes de

    2015-01-01

    A Implantologia tem ganho popularidade na medicina dentária pelos resultados previsíveis em reabilitações de áreas edêntulas, permitindo minimizar as consequências funcionais, fonéticas e estéticas que advém da perda de dentes através de uma solução fixa que satizfaz os pacientes. Esta é uma revisão da literatura existente sobre factores de risco, fracassos e complicações inerentes ao tratamento com implantes dentários. Categorizam-se os factores de risco em implantologia co...

  5. Evaluation of Antioxidant Activities of Aqueous Extracts and Fractionation of Different Parts of <em>Elsholtzia em>ciliata>

    Yuangang Zu

    2012-05-01

    Full Text Available The aim of this study was to investigate the antioxidant and free-radical scavenging activity of extract and fractions from various parts of <em>Elsholtzia ciliataem>. The inflorescences, leaves, stems and roots of <em>E. ciliataem> were extracted separately and two phenolic component enrichment methods: ethyl acetate-water liquid-liquid extraction and macroporous resin adsorption-desorption, were adopted in this study. The antioxidant activities of water extracts and fractions of <em>E. ciliataem> were examined using different assay model systems <em>in vitroem>. The fraction root E (purified by HPD300 macroporous resin exhibited the highest total phenolics content (497.2 ± 24.9 mg GAE/g, accompanied with the highest antioxidant activity against various antioxidant systems <em>in vitroem> compared to other fractions. On the basis of the results obtained, <em>E. ciliataem> extracts can be used potentially as a ready accessible and valuable bioactive source of natural antioxidants.

  6. Using open hole and cased-hole resistivity logs to monitor gas hydrate dissociation during a thermal test in the mallik 5L-38 research well, Mackenzie Delta, Canada

    Anderson, B.I.; Collett, T.S.; Lewis, R.E.; Dubourg, I.

    2008-01-01

    Gas hydrates, which are naturally occurring ice-like combinations of gas and water, have the potential to provide vast amounts of natural gas from the world's oceans and polar regions. However, producing gas economically from hydrates entails major technical challenges. Proposed recovery methods such as dissociating or melting gas hydrates by heating or depressurization are currently being tested. One such test was conducted in northern Canada by the partners in the Mallik 2002 Gas Hydrate Production Research Well Program. This paper describes how resistivity logs were used to determine the size of the annular region of gas hydrate dissociation that occurred around the wellbore during the thermal test in the Mallik 5L-38 well. An open-hole logging suite, run prior to the thermal test, included array induction, array laterolog, nuclear magnetic resonance and 1.1-GHz electromagnetic propagation logs. The reservoir saturation tool was run both before and after the thermal test to monitor formation changes. A cased-hole formation resistivity log was run after the test.Baseline resistivity values in each formation layer (Rt) were established from the deep laterolog data. The resistivity in the region of gas hydrate dissociation near the wellbore (Rxo) was determined from electromagnetic propagation and reservoir saturation tool measurements. The radius of hydrate dissociation as a function of depth was then determined by means of iterative forward modeling of cased-hole formation resistivity tool response. The solution was obtained by varying the modeled dissociation radius until the modeled log overlaid the field log. Pretest gas hydrate production computer simulations had predicted that dissociation would take place at a uniform radius over the 13-ft test interval. However, the post-test resistivity modeling showed that this was not the case. The resistivity-derived dissociation radius was greatest near the outlet of the pipe that circulated hot water in the wellbore

  7. Rodent hosts of <em>Maritrema> sp. (Digenea, Microphallidae in Sardinia Island

    Juan Carlos Casanova

    2003-10-01

    Full Text Available Prospections on helminth fauna of rodents were carried out in the Cedrino river (Eastern of Sardinia island. Twelve <em>Rattus rattusem> (L., 1758 and eight <em>Mus domesticusem> (Schwarz & Schwarz, 1943 were captured by Sherman traps. Parasitological study revealed in <em>R. rattusem> the presence of an intestinal helminth belonging to the genus <em>Maritrema> (family Microphallidae. The transmission of this Digenetic Trematode among vertebrates involves the participation of aquatic invertebrate organisms, molluscs and crustacea, acting as intermediate hosts. Dissection of 117 individuals of the Amphipod Crustacea <em>Gammarus italicusem>, collected in the same biotope, allowed the detection of encysted metacercariae. These larvae constitute the infesting stage of the parasite for vertebrates, acting these as definitive hosts ingesting parasitized crustacea as preys. Adults of <em>Maritrema> sp. were also obtained experimentally in the laboratory mice (<em>Mus domesticusem> CD1 strain. These were infested by inoculating them, using gastric probe, metacercarial cysts isolated from <em>G. italicusem>. Post-infection mice dissection was performed at different intervals of time getting adults in various maturity stages. Experimental facts confirm that <em>Maritrema> sp., as it occurs in other trematodes, do not present strict specificity to the definitive host, being able to develop as well in <em>Mus>. In nature, the presence or absence of this digenean in mammals species will be dependent of host ethological factors, mainly related to feeding habitats. This study was partially supported by the ?Comissionat per Recerca i Universitats de la Generalitat de Catalunya? 2001SGR00088.

  8. Adaptabilidade e estabilidade em aveia em ambientes estratificados

    Bertan Ivandro

    2005-01-01

    Full Text Available Vinte cultivares de aveia (Avena sativa L. foram avaliados para rendimento de grãos nas safras agrícolas de 2001 e 2002 em nove locais dos estados do Paraná, Rio Grande do Sul e São Paulo, com o objetivo de avaliar as estimativas dos componentes de adaptabilidade e estabilidade do rendimento de grãos em ambientes favoráveis e desfavoráveis em presença e ausência de aplicação de fungicida. Foi empregada a metodologia de EBERHART & RUSSELL (1966. A presença de significância para anos, genótipos, fungicidas e locais, indicou comportamento diferencial de genótipos frente às variações de ambiente e a aplicação de fungicida, nas condições de ambientes favoráveis e desfavoráveis. A aplicação de fungicida e o favorecimento do ambiente de cultivo afetaram intensamente os parâmetros de adaptabilidade (b1 e estabilidade (s²d i, indicando que estas estimativas devam ser realizadas em ambientes estratificados, apesar de nenhuma constituição genética ter evidenciado o biótipo ideal, conforme preconizado pelo modelo adotado.

  9. A Novel Apoptosis Correlated Molecule: Expression and Characterization of Protein Latcripin-1 from <em>Lentinula em>edodes> C91–3

    Min Huang

    2012-05-01

    Full Text Available An apoptosis correlated molecule—protein Latcripin-1 of <em>Lentinula> edodesem> C91-3—was expressed and characterized in <em>Pichia pastorisem> GS115. The total RNA was obtained from <em>Lentinula edodesem> C91–3. According to the transcriptome, the full-length gene of Latcripin-1 was isolated with 3'-Full Rapid Amplification of cDNA Ends (RACE and 5'-Full RACE methods. The full-length gene was inserted into the secretory expression vector pPIC9K. The protein Latcripin-1 was expressed in <em>Pichia pastorisem> GS115 and analyzed by Sodium Dodecylsulfonate Polyacrylate Gel Electrophoresis (SDS-PAGE and Western blot. The Western blot showed that the protein was expressed successfully. The biological function of protein Latcripin-1 on A549 cells was studied with flow cytometry and the 3-(4,5-Dimethylthiazol-2-yl-2,5-Diphenyl-tetrazolium Bromide (MTT method. The toxic effect of protein Latcripin-1 was detected with the MTT method by co-culturing the characterized protein with chick embryo fibroblasts. The MTT assay results showed that there was a great difference between protein Latcripin-1 groups and the control group (<em>p em>< 0.05. There was no toxic effect of the characterized protein on chick embryo fibroblasts. The flow cytometry showed that there was a significant difference between the protein groups of interest and the control group according to apoptosis function (<em>p em>< 0.05. At the same time, cell ultrastructure observed by transmission electron microscopy supported the results of flow cytometry. The work demonstrates that protein Latcripin-1 can induce apoptosis of human lung cancer cells A549 and brings new insights into and advantages to finding anti-tumor proteins.

  10. Allometric and Isometric variations in the Italian <em>Apodemus sylvaticusem> and <em>Apodemus flavicollisem> with respect to the conditions of allopatry and sympatry / Variazioni allometriche e isometriche in <em>Apodemus sylvaticusem> e <em>Apodemus flavicollisem> italiani, rispetto alle condizioni di allopatria e simpatria

    Giovanni Amori

    1986-12-01

    Full Text Available Abstract In Italy there are two species of <em>Apodemus> (<em>Sylvaemus>: <em>Apodemus sylvaticusem> on the mainland and the main island, and <em>Apodemus flavicollisem> only on the mainland. The trend of some morphometric characters of the skull (incisive foramen length - FI; interorbital breadth = IO; length of palatal bridge = PP; upper alveolar length = $M^1M^3$ was analized and some theoretical models verified for <em>A. sylvaticusem>. If one considers the sympatric population of <em>A. sylvaticusem> and <em>A. flavicollisem> simultaneously the characters PP, IO and $M^1M^3$ appear significantly isometric being directly correlated ($P leq O.O1$, while FI character results allometric with respect to the previous ones, as expected. If one considers the sympatric populations of each of the species separately, the scenario is different. For <em>A. sylvaticusem> only PP and $M^1M^3$ are isometric ($P leq 0.05$. For <em>A. flavicollisem> only $M^1M^3$ and FI appear to be correlated, although not as significantly as for <em>A. sylvaticusem> ($P le 0.05$; one tail. The insular populations of <em>A. sylvaticusem> do not show significant correlations, except for FI and $M^1M^3$ ($P le 0.05$. On the contrary, considering all populations, sympatric and allopatric, of <em>A. sylvaticusem> at the same time are significant correlations ($P le 0.05$ in all combinations of characters, except for those involving the IO. We suggest that the isometric relations in sympatric assemblages are confined within a morphological range available to the genus <em>Apodemus>. In such a space, the two species are split in two different and innerly homogeneous distributions. We found no evidence to confirm the niche variation hypothesis. On the contrary, the variability expressed as SO or CV's appears higher in the sympatric populations than in the allopatric ones, for three of the four characters, confirming previous results

  11. Parasitic zoonoses: survey in foxes (<em>Vulpes vulpesem> in the northern Apennines / Zoonosi parassitarie: indagini in volpi (<em>Vulpes vulpesem> dell'Appennino settentrionale

    Vittorio Guberti

    1991-07-01

    Full Text Available Abstract A parasitological survey on 153 foxes was carried out in the northern Apennines, during the period 1984-1987. The following parasites were identified: <em>Toxocara canisem> (46.4%, <em>Taenia> sp. (17%, <em>Uncinaria stenocephalaem> (11.8%, <em>Mesocestoides lineatusem> (11.1%, <em>Ancylostoma caninumem> (3.9%, <em>Taenia hydatigenaem> (3.3%, <em>Trichuris vulpisem> (3.3%, <em>Dipylidium caninumem> (2.6%, <em>Taenia crassicepsem> (2%. All foxes were negative for <em>Trichinella> sp. A statistical analysis was performed to evaluate differences in the parasitic fauna according to the sex and age classes of the hosts. The role that the fox could have as a reservoir of helminthic zoonoses is discussed. The results are compared with those of similar studies carried out in Italy. Riassunto Nel periodo 1984-1987 è stata condotta un'indagine parassitologica su 153 volpi abbattute nell'Appennino romagnolo. Sono stati reperiti i seguenti parassiti: <em>Toxocara canisem> (46,4%, <em>Taenia> sp. (17%, <em>Uncinaria stenocephalaem> (11,8%, <em>Mesocestoides lineatusem> (11,1%, <em>Ancylostoma caninumem> (3,9%, <em>Taenia hydatigenaem> (3,3%, <em>Trichuris vulpisem> (3,3%, <em>Dipylidium caninumem> (2,6%, <em>Taenia crassicepsem> (2%. Tutte le volpi esaminate sono risultate negative per <em>Trichinella> sp. È stata effettuata l'analisi statistica dei dati per evidenziare eventuali differenze della fauna parassitaria in relazione al sesso e all'età delle volpi. Sulla base dei dati ottenuti viene discussa l'importanza che la Volpe può assumere come serbatoio di zoonosi elmintiche. I risultati acquisiti sono inoltre comparati con quelli ottenuti in analoghe ricerche condotte in Italia.

  12. Allozymic and biometric variation in <em>Dryomys nitedulaem> (Pallas, 1778

    Maria Grazia Filippucci

    1995-05-01

    Full Text Available Abstract Biometric and genetic variation were analysed among populations of <em>D. nitedulaem> from Italy, Balkan Peninsula, Asia Minor and Israel. The biometric analysis was carried out on 84 specimens using 13 linear skull measurements. Variations in metrical characters among samples were studied by standard and multivariate analyses. The genetic analysis was carried out on 29 specimens by electrophoresis of 40 gene loci. In both analyses the Israeli sample was the most distinct. Skulls of Israeli specimens are characterized by longer mandibular tooth row, higher rhamus mandibulae, longer bullae, and narrower braincase breadth, rostra1 breadth and interorbital constriction. Electrophoretically the Israeli sample can be discriminated from European populations by four loci (<em>Ldh-1em>, <em>G6pdhem>, <em>Pep-1em>, and <em>Lap-2em> fixed for new alleles. The mean value of Nei's genetic distance between Israeli and European populations was <em>D> = 0.186, ranging from 0.153 to 0.227. The Israeli population, commonly attributed to the taxon <em>phrygius>, was different from this by biometric analysis. <em>D. n. phrygiusem> from the topotype locality in Asia Minor clustered with the European population from Turkish Thrace. In order to clarify the phylogenetic relationships of the Israeli forest dormouse, a comparison with other populations from the Caucasus and Iran and with <em>Dryomys lanigerem> from Turkey is suggested. Riassunto Variabilità genetica e biometrica in <em>Dryomys nitedulaem> (Pallas, 1778 - Variabilità biometrica e genetica sono state analizzate tra popolazioni di <em>D. nitetulaem> provenienti da Italia, Penisola Balcanica, Asia Minore ed Israele. L'analisi biometrica è stata condotta su 84 esemplari mediante 13 misurazioni craniche lineari. La variazione nei caratteri metrici tra i campioni è stata studiata mediante analisi standard e multivariata

  13. First sign of <em>Clethrionomys glareolusem> in the Po valley plain / Prima segnalazione in Pianura Padana di <em>Clethrionomys glareolusem>

    Luis Nieder

    1987-07-01

    Full Text Available Abstract The presence of <em>Clethrionomys glareolusem> (Schreber, 1790 populations is reported in the Po valley, formerly considered outside the distribution area of the species. An initial series of captures was made in the high-water area of the Po near S. Nazzaro (Monticelli d'Ongina - PC following with research was extended along the river's banks in Emilia both upstream and downstream. The search for this species was carried out by analysing food pellets relating to <em>Strix alucoem>, <em>Tyto albaem> e <em>Athene noctuaem>, thought to be among the most common predators of these intensive herbaceous and arboreal agricultural biocoenosis. The information we gathered was integrated with other Authors' unpublished and bibliographical data. The presence of <em>C. glareolusem> was noted in habitats quite different from the expected ones. Many of the problems raised by the presence of this species in "islands" along the main body of the Po river and its tributaries, and by its presumed absence from particulary suitable environments such as the Carrega woods, the Ticino park and Mesola wood must still be resolved. Riassunto Viene segnalata la presenza di popolazioni di <em>Clethrionomys glareolusem> (Schreber 1790 nella pianura Padana precedentemente considerata al di fuori dell'areale della specie. A partire da una prima serie di catture nell'area golenale del Po presso S. Nazzaro (Monticelli d'Ongina - PC, si è successivamente proceduto ad allargare l'area di ricerca lungo l'argine emiliano del Po, sia a monte sia a valle. La ricerca di questa specie è avvenuta tramite l'analisi di boli alimentari relativi a <em>Strix alucoem>, <em>Tyto albaem> e <em>Athene noctuaem>, ritenuti tra i più comuni predatori di queste biocenosi agricole intensive erbacee ed arboree. I dati da noi raccolti sono stati integrati con quelli bibliografici e inediti di altri Autori. È stata riscontrata la presenza

  14. Cuidados paliativos em cuidados intensivos

    Fonseca, Sandrina Fernandes de Andrade

    2012-01-01

    Relatório de prática clínica apresentado à Escola Superior de Saúde Dr. Lopes Dias do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de mestre em Cuidados Paliativos

  15. Action of Chitosan Against <em>Xanthomonas> Pathogenic Bacteria Isolated from <em>Euphorbia pulcherrimaem>

    Yanli Wang

    2012-06-01

    Full Text Available The antibacterial activity and mechanism of two kinds of chitosan were investigated against twelve <em>Xanthomonas> strains recovered from <em>Euphorbia pulcherrimaem>. Results indicated that both chitosans markedly inhibited bacterial growth based on OD loss. Furthermore, the release of DNA and RNA from three selected strains was increased by both chitosans. However, the release of intracellular proteins was inhibited by both chitosans at different concentration and incubation times, except chitosan A at 0.1 mg/mL for 0.5 h incubation and 0.2 mg/mL for 2.0 h incubation increased the release of proteins, indicating the complexity of the interaction and cell membranes, which was affected by incubation time, bacterial species, chitosan type and concentration. Transmission electron microscopic observations revealed that chitosan caused changes in protoplast concentration and surface morphology. In some cells, the membranes and walls were badly distorted and disrupted, while other cells were enveloped by a thick and compact ribbon-like layer. The contrary influence on cell morphology may explain the differential effect in the release of material. In addition, scanning electron microscope and biofilm formation test revealed that both chitosans removed biofilm biomass. Overall, this study showed that membrane and biofilm play an important role in the antibacterial mechanism of chitosan.

  16. Preparation and Characterization of <em>O>-Acylated Fucosylated Chondroitin Sulfate from Sea Cucumber

    Na Gao

    2012-08-01

    Full Text Available Fucosylated chondroitin sulfate (FuCS, a kind of complex glycosaminoglycan from sea cucumber, has potent anticoagulant activity. In order to understand the relationship between structures and activity, the depolymerized FuCS (dFuCS was chosen to prepare its derivates by selective substitution at OH groups. Its <em>O>-acylation was carried out in a homogeneous way using carboxylic acid anhydrides. The structures of<em> Oem>-acylated derivatives were characterized by NMR. The results indicated that the 4-<em>O>-sulfated fucose residues may be easier to be acylated than the other ones in the sulfated fucose branches. But the<em> Oem>-acylation was always accompanied by the β-elimination, and the degree of elimination was higher as that of acylation was higher. The results of clotting assay indicated that the effect of partial <em>O>-acylation of the dFuCS on their anticoagulant potency was not significant and the <em>O>-acylation of 2-OH groups of 4-<em>O>-sulfated fucose units did not affect the anticoagulant activity.

  17. Wavelet <em>q->Fisher Information for Scaling Signal Analysis

    Joel Trejo-Sanchez

    2012-08-01

    Full Text Available Abstract: This article first introduces the concept of wavelet <em>q>-Fisher information  and then derives a closed-form  expression of this quantifier for scaling signals of parameter α.  It is shown that this information measure appropriately describes the complexities  of scaling signals and provides further analysis flexibility with the parameter<em> qem>. In the limit of <em>q → 1,em> wavelet <em>q>-Fisher information  reduces to the standard wavelet Fisher information  and for <em>q  > 2em> it reverses its behavior. Experimental results on synthesized fGn signals validates the level-shift  detection capabilities of wavelet q-Fisher information. A comparative study also shows that wavelet<em> qem>-Fisher information  locates structural changes in correlated and anti-correlated fGn signals in a way comparable with standard breakpoint location techniques but at a fraction of the time. Finally, the application of this quantifier to H.<em>263 em>encoded video signals is presented.

  18. <em>Ipomoea aquaticaem> Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity

    A. Hamid A. Hadi

    2012-05-01

    Full Text Available In the Indian system of traditional medicine (Ayurveda it is recommended to consume <em>Ipomoea em>aquatica> to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of <em>I. aquaticaem> against liver damage were evaluated in thioacetamide (TAA-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD rats were orally fed with <em>I. aquaticaem> (250 and 500 mg/kg for two months along with administration of TAA (i.p injection 200 mg/kg three times a week for two months. The results showed that the treatment of <em>I. aquaticaem> significantly lowered the TAA-induced serum levels of hepatic enzyme markers (ALP, ALT, AST, protein, albumin, bilirubin and prothrombin time. The hepatic content of activities and expressions SOD and CAT that were reduced by TAA were brought back to control levels by the plant extract supplement. Meanwhile, the rise in MDA level in the TAA receiving groups also were significantly reduced by <em>I. aquaticaem> treatment. Histopathology of hepatic tissues by H&E and Masson trichrome stains displayed that <em>I. aquaticaem> has reduced the incidence of liver lesions, including hepatic cells cloudy swelling, infiltration, hepatic necrosis, and fibrous connective tissue proliferation induced by TAA in rats. Therefore, the results of this study show that the protective effect of <em>I. aquaticaem> in TAA-induced liver damage might be contributed to its modulation on detoxification enzymes and its antioxidant and free radical scavenger effects. Moreover, it confirms a scientific basis for the traditional use of <em>I. aquaticaem> for the treatment of liver disorders.

  19. Negative-Pressure Cavitation Extraction of Four Main Vinca Alkaloids from <em>Catharanthus em>roseus> Leaves

    Yuangang Zu

    2012-07-01

    Full Text Available In the present study, an improved method termed negative-pressure cavitation extraction (NPCE followed by reverse phase high-performance liquid chromatography (RP-HPLC was developed for the extraction and quantification of vindoline (VDL, catharanthine (CTR, vincristine (VCR and vinblastine (VLB from <em>Catharanthus roseus em>leaves. The optimized method employed 60-mesh particles, 80% ethanol, a negative pressure of −0.075 MPa, a solid to liquid ratio of 1:20, 30 min of extraction and three extraction cycles. Under these optimized conditions, the extraction yields of VDL, CTR, VCR and VLB are 0.5783, 0.2843, 0.018 and 0.126 mg/g DW, respectively. These extraction yields are equivalent to those from the well-known ultrasonic extraction method and higher than the yields from maceration extraction and heating reflux extraction. Our results suggest that NPCE-RP-HPLC represents an excellent alternative for the extraction and quantification of vinca alkaloids for pilot- and industrial-scale applications.

  20. Cefaleia em salvas: aspectos clinicos e terapeuticos em 26 casos

    Wilson Luiz Sanvito

    1980-12-01

    Full Text Available Vinte e seis casos de cefaléia-em-salvas são estudados do ponto de vista clínico e terapêutico. Nos aspectos clínicos são ressaltados a dramaticidade deste tipo de cefaléia, o nítido predomínio no sexo masculino, a média de idade dos pacientes, a presença de manifestações associadas e os fatores desencadeantes das crises nos períodos suscetíveis. Do ponto de vista terapêutico três esquemas medicamentosos foram utilizados: maleato de metisergida, prednisona e associação de ambas as drogas. Em 88,3% dos casos um resultado significativo foi alcançado, traduzido por melhora ou abolição das crises.

  1. Phenolic Compounds and Antioxidant Activity of Bulb Extracts of Six <em>Lilium> Species Native to China

    Lixin Niu

    2012-08-01

    Full Text Available Lily (<em>Lilium> is used as an important edible and medical plant species with a vague taxonomic classification and a long history in China. Bulbs of six <em>Lilium> species (<em>L. regaleem>,> L. concolorem>,> L. pumilumem>,> L. leucanthumem>,> L. davidii var. unicolorem> and <em>L. lancifoliumem> native to China were investigated with a view to their exploitation as a potential source of natural antioxidants due to their phenolic composition and dietary antioxidant potential. The results showed that all bulb extracts exhibited strong antioxidant activities, which generally correlated positively with the total phenolic contents (r = 0.68 to 0.94, total flavonoid contents (r = 0.51 to 0.89 and total flavanol contents (r = 0.54 to 0.95. High-performance liquid chromatography (HPLC analysis revealed that rutin and kaempferol were the major phenolic components in the extracts. Hierarchical cluster analysis showed that <em>L. regaleem> belonged to the group with high phenolic content and strong antioxidant power. <em>L. concolorem> and <em>L. pumilumem> were arranged in one group characterized by moderate phenolic content and antioxidant capacity, while <em>L. leucanthumem>, <em>L. davidii var. unicolorem> and <em>L. lancifoliumem> were clustered in the third group with low phenolic content and weak antioxidant activity. These strongly suggest that lily bulbs may serve as a potential source of natural antioxidant for food and pharmaceutical applications.

  2. Fatores de risco cardiovascular em alcoolistas em tratamento

    Mayla Cardoso Fernandes Toffolo

    2013-06-01

    Full Text Available OBJETIVO: Avaliar a presença de fatores de risco cardiovascular, com ênfase na hipertensão e na adiposidade corporal, em alcoolistas abstinentes ou não abstinentes em tratamento. MÉTODO: Trata-se de um estudo transversal com 65 pacientes alcoolistas em tratamento no CAP-Sad. O grau de dependência do álcool foi avaliado pelo SADD (Short Alcohol Dependence Data e o uso de outras drogas, pelo ASSIST (Alcohol Smoking and Substance Involvement Screening Test. Foram avaliados o perfil bioquímico e o antropométrico dos usuários. RESULTADOS: Participaram do estudo 42 homens e 23 mulheres. A maioria dos participantes (67,74% apresentou dependência alcoólica grave, com uso de álcool associado principalmente a cigarro (66,15%. A média da circunferência da cintura (CC foi significativamente maior entre os abstinentes, em comparação aos não abstinentes (AB: 88,15 ± 15,95 x NA: 81,04 ± 9,86; p = 0,03. Pacientes abstinentes há mais tempo tiveram maior sobrepeso/obesidade e adiposidade abdominal (CC do que os não abstinentes e abstinentes recentes, com razão de chances de 5,25. Os abstinentes apresentaram razão de chances de 3,38 para %GC acima da média, independente do tempo de abstinência. CONCLUSÃO: Pacientes alcoolistas abstinentes apresentam mais sobrepeso/ obesidade, adiposidade corporal (%GC e abdominal (CC do que os não abstinentes. É importante o acompanhamento multiprofissional no tratamento de alcoolistas com abordagem para fatores de risco cardiovasculares, principalmente evitando o ganho de peso.

  3. Fadiga em plataformas offshore fixas com modelos em elementos finitos

    Roberto Taier

    2002-09-01

    Full Text Available Quatro juntas tubulares de uma plataforma offshore fixa foram modeladas em elementos finitos para o cálculo das vidas à fadiga e comparação com os resultados obtidos através de modelos convencionais em elementos de barras. Foram também cotejados os fatores de concentração de tensões (SCF's, obtidos com base nas formulações paramétricas, com os calculados através dos modelos em elementos finitos. Os objetivos foram averiguar a validade do refinamento do cálculo da fadiga em juntas críticas da plataforma e avaliar as suas conseqüências na elaboração do plano de inspeção. Os resultados permitiram concluir que a análise por elementos finitos torna-se recomendada para juntas que não apresentam tipo e/ou comportamento compatíveis com as configurações padronizadas, normalmente utilizadas pelos programas. Das quatro juntas analisadas, duas delas não necessitariam fazer parte do plano de inspeção da plataforma.Four tubular joints of a fixed offshore platform were modelled using finite elements to evaluate respective fatigue lifes and comparison with the results obtained from conventional models in frame elements. Stress concentration factors (SCF's calculated from parametric formulas were also compared with those obtained from finite elements models. The results of this work have the intention of verifying the validity of the refinement of fatigue analysis on critical joints of the platform and the evaluation of its consequences in the inspection plan. Obtained results show that finite elements analysis is recommended for joints whose type and/or behaviour is not consistent with standard models, used by computational programs. From four analised joints, two of them would not need to be part of inspection plan.

  4. Phytochemical Composition, Antioxidant and Xanthine Oxidase Inhibitory Activities of <em>Amaranthus cruentusem> L. and <em>Amaranthus hybridusem> L. Extracts

    Jeanne F. Millogo

    2012-06-01

    Full Text Available This paper describes a preliminary assessment of the nutraceutical value of <em>Amaranthus cruentus (A. cruentusem> and <em>Amaranthus hybridus (A. hybridusem>, two food plant species found in Burkina Faso. Hydroacetonic (HAE, methanolic (ME, and aqueous extracts (AE from the aerial parts were screened for <em>in vitroem> antioxidant and xanthine oxidase inhibitory activities. Phytochemical analyses revealed the presence of polyphenols, tannins, flavonoids, steroids, terpenoids, saponins and betalains. Hydroacetonic extracts have shown the most diversity for secondary metabolites. The TLC analyses of flavonoids from HAE extracts showed the presence of rutin and other unidentified compounds. The phenolic compound contents of the HAE, ME and AE extracts were determined using the Folin–Ciocalteu method and ranged from 7.55 to 10.18 mg Gallic acid equivalent GAE/100 mg. Tannins, flavonoids, and flavonols ranged from 2.83 to 10.17 mg tannic acid equivalent (TAE/100 mg, 0.37 to 7.06 mg quercetin equivalent (QE /100 mg, and 0.09 to 1.31 mg QE/100 mg, respectively. The betacyanin contents were 40.42 and 6.35 mg Amaranthin Equivalent/100 g aerial parts (dry weight in <em>A. cruentusem> and <em>A. hybridusem>, respectively. Free-radical scavenging activity expressed as IC50 (DPPH method and iron reducing power (FRAP method ranged from 56 to 423 µg/mL and from 2.26 to 2.56 mmol AAE/g, respectively. Xanthine oxidase inhibitory activities of extracts of <em>A. cruentus em>and <em>A. hybridusem> were 3.18% and 38.22%, respectively.<em> em>The> A. hybridusem> extract showed the best antioxidant and xanthine oxidase inhibition activities. The results indicated that the phytochemical contents of the two species justify their traditional uses as nutraceutical food plants.

  5. Damage caused by <em>Skrjabingylus nasicolaem> (Leuckart, 1842, Metastrongylidae, to weasels (<em>Mustela nivalisem> L. in North-Western Italy

    Claudio Prigioni

    1995-12-01

    Full Text Available Abstract The percentage of infestation (incidence and the degree of damage caused by <em>Skrjabingylus nasicolaem> were analysed in 15 fresh skulls of weasels (<em>Mustela nivalisem> collected in Pavia province (Northern Italy during 1986-89 and in 79 preserved skulls from the Civic Museum of Natural History of Genoa (Liguria region. The incidence was 66.6% for the first sample of weasels and 54.4% for the second one; the mean degree of damage, assessed according King's methods, was 3.7 and 2.6 respectively. Although no significant difference in <em>Skrjabingylus> prevalence was recorded in relation to sex and age of weasels, a trend of increase in parasite incidence was observed from young to adults in the sample of weasels from the Museum of Genoa. <em>Apodemus sylvaticusem>, which was the staple in the diet of weasels collected in Pavia province, could be considered the main paratenic host of the skrjabingylosis in northern Italian plain. Riassunto Danni causati da <em>Skrjabingylus nasicolaem> (Leuckart, 1942, Metastrongylidae, nella donnola <em>Mustela nivalisem> in Italia nord occidentale - La percentuale di infestazione (incidenza e l'entità del danno causato da S<em>krjabingylus nasicolaem> sono state analizzate in 15 donnole (<em>Mustela nivalisem> reperite in aree coltivate della Provincia di Pavia nel 1986-89 e in 79 esemplari appartenenti alla collezione del Museo Civico di Storia Naturale di Genova. L'incidenza dell'infestazione è risultata del 66,6% per il primo campione e del 54,4% per il secondo, mentre l'entità media del danno, valutata secondo il metodo proposto da King, è stata di 3,7 e 2,6 rispettivamente. Sebbene non sia stata rilevata nessuna differenza signiticativa della prevalenza parassitaria in relazione al sesso ed all'età delle donnole, è stata evidenziata, per il campione del Museo di Genova, una tendenza all'incremento dell'incidenza dai

  6. Soropositividade para brucelose em suínos em abatedouros

    Diego C. Rosa

    2012-07-01

    Full Text Available O presente trabalho teve por objetivo investigar a soropositividade para brucelose em suínos em abatedouros. Foram coletados 910 soros de suínos, procedentes de 30 propriedades, abatidos em frigoríficos da região central do estado de São Paulo, e submetidos às provas de soroaglutinaçao com antígeno tamponado acidificado (AAT e 2-Mercaptoetanol (2-Me objetivando determinar a ocorrência da enfermidade nesta espécie. Do total de soros avaliados foram observados 25 (2,7% animais reagentes ao AAT pertencentes a 10 propriedades, caracterizando 36% de propriedades positivas. Dos animais positivos ao AAT, 16% apresentaram titulo de 25 (incompleto e 52% titulo de 25 na soroaglutinação lenta (SAL, 8% apresentaram titulo de 50 incompleto na SAL e 25 incompleto no 2-ME e 8% apresentaram titulo de 50 na SAL e 25 no 2-ME. Estes resultados demonstram o elevado percentual de propriedades positivas para brucelose nesta região e ressaltam a necessidade de implementação de programas oficiais efetivos para o controle da brucelose suína.

  7. <em>Hedyotis diffusaem> Willd Inhibits Colorectal Cancer Growth <em>in Vivoem> via Inhibition of STAT3 Signaling Pathway

    Jun Peng

    2012-05-01

    Full Text Available Signal Transducer and Activator of Transcription 3 (STAT3, a common oncogenic mediator, is constitutively activated in many types of human cancers; therefore it is a major focus in the development of novel anti-cancer agents. <em>Hedyotis diffusaem> Willd has been used as a major component in several Chinese medicine formulas for the clinical treatment of colorectal cancer (CRC. However, the precise mechanism of its anti-tumor activity remains largely unclear. Using a CRC mouse xenograft model, in the present study we evaluated the effect of the ethanol extract of<em> Hedyotis diffusaem> Willd (EEHDW on tumor growth <em>in vivoem> and investigated the underlying molecular mechanisms. We found that EEHDW reduced tumor volume and tumor weight, but had no effect on body weight gain in CRC mice, demonstrating that EEHDW can inhibit CRC growth <em>in vivoem> without apparent adverse effect. In addition, EEHDW treatment suppressed STAT3 phosphorylation in tumor tissues, which in turn resulted in the promotion of cancer cell apoptosis and inhibition of proliferation. Moreover, EEHDW treatment altered the expression pattern of several important target genes of the STAT3 signaling pathway, <em>i.e.>, decreased expression of Cyclin D1, CDK4 and Bcl-2 as well as up-regulated p21 and Bax. These results suggest that suppression of the STAT3 pathway might be one of the mechanisms by which EEHDW treats colorectal cancer.

  8. Trabalho em grupo com enlutados

    Melissa Pascoal

    2012-12-01

    Full Text Available A cada dia temos mais famílias vivenciando o luto gerado por homicídios, acidentes e violência, e isso tem causado alguns problemas psicológicos para as pessoas que estão nesta situação. Este artigo é um relato da experiência profissional vivida no Hospital e Maternidade Mauá com um grupo de autoajuda para pacientes em processo de luto, e seu objetivo é compartilhar a experiência e difundir este trabalho. Em 15 encontros pré-estruturados de acordo com a demanda apresentada pelo próprio grupo, foi possível trabalhar diversos temas relacionados à perda que influenciaram as participantes e ao mesmo tempo proporcionaram, além de conforto, uma possibilidade de identificação e troca, e consequentemente o ressurgimento da autoconfiança. Por meio da articulação da teoria com a prática, é evidenciado que o atendimento em grupo para enlutados é uma alternativa viável que trouxe resultados positivos e inspiradores e sua divulgação é importante para ampliar horizontes e criar novas possibilidades.

  9. Trophic systems and chorology: data from shrews, moles and voles of Italy preyed by the barn owl / Sistemi trofici e corologia: dati su <em>Soricidae>, <em>Talpidae> ed <em>Arvicolidae> d'Italia predati da <em>Tyto albaem> (Scopoli 1769

    Longino Contoli

    1986-12-01

    Full Text Available Abstract In small Mammals biogeography, available data are up to now by far too scanty for elucidate the distribution of a lot of taxa, especially with regard to the absence from a given area. In this respect, standardized quantitative sampling techniques, like Owl pellets analysis can enable not only to enhance faunistic knowledges, but also to estimate the actual absence probability of a given taxon "m", lacking from the diet of an individual raptor. For the last purpose, the relevant frequencies of "m" in the other ecologically similar sites of the same raptor species diets are averaged ($f_m$ : the relevant standard error (multiplicated by a coefficient, according to the desired degree of accuracy, in relation of the integral of probabilities subtracted ($overline{F}_m - a E$: then, the probability that a single specimen is not pertaining to "m" is obtained ($P_0 = 1 - F_m + a E$; lastly, the desiderate accuracy probability ($P_d$ is chosen. Now, "$N_d$" (the number of individuals of all prey species in a single site needed for obtain, with the desired probability, a specimen at least of "m" is obtained through $$N = frac{ln P_d}{ln P_0}$$ Obviously, every site-diet with more than "N" preyed individuals and without any "i" specimen is considered to be lacking of such taxon. A "usefulness index" for the above purposes is outlined and checked about three raptors. Some exanples about usefulness of the Owl pellet analysis method in biogeography are given, concerning <em>Tyto albaem> diets in peninsular Italy about: - <em>Sorex minutusem>, lacking in some quite insulated areas; - <em>Sorex araneusem> (sensu stricto, after GRAF et al., 1979, present also in lowland areas in Emilia-Romagna; - <em>Crocidura suaveolensem> and - <em>Suncus etruscusem>, present also in the southermost part of Calabria (Reggio province; - <em>Talpa caecaem>, present also in the Antiapennines of Latium (Cimini mounts; - <em>Talpa romanaem

  10. Meroterpenes from Endophytic Fungus A1 of Mangrove Plant <em>Scyphiphora hydrophyllaceaem>

    Peter Proksch

    2012-09-01

    Full Text Available Four new meroterpenes, guignardones F–I (14, together with two known compounds guignardones A (5 and B (6 were isolated from the endophytic fungus A1 of the mangrove plant <em>Scyphiphora hydrophem>yllacea>. Their structures and relative configurations were elucidated by spectroscopic data and single-crystal X-ray crystallography. A possible biogenetic pathway of compounds 16 was also proposed. All compounds were evaluated for inhibitory activity against methicillin-resistant <em>Staphylococcus aureusem> (MRSA and <em>Staphylococcus aureusem>.

  11. Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from <em>Rosmarinus officinalisem>>

    Chunjian Zhao

    2012-09-01

    Full Text Available Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from <em>Rosmarinus officinalisem>. Eight ionic liquids, with different cations and anions, were investigated in this work and [C8mim]Br was selected as the optimal solvent. Ultrasound extraction parameters, including soaking time, solid–liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology. The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from <em>R. officinalisem>> em>compared with traditional reference extraction methods. Ionic liquids are considered to be green solvents, in the ultrasound-assisted extraction of key chemicals from medicinal plants, and show great potential.

  12. Morphological identification of the Soprano Pipistrelle (<em>Pipistrellus pygmaeusem> Leach, 1825 in Croatia.

    Igor Pavlinić

    2008-07-01

    Full Text Available Abstract After the discovery of two different phonic types within the common pipistrelle (<em>Pipistrellus pipistrellusem>, mtDNA analysis confirmed the existence of two separate species named as common pipistrelle (<em>P. pipistrellusem> and soprano pipistrelle (<em>P. pygmaeusem>. The discrimination of these two cryptic species using external characters and measures has proved to be somewhat problematic. We examined two colonies of soprano pipistrelle from Donji Miholjac, Croatia. As a result, only two characters proved to be of help for field identification: wing venation (89% of cases and penis morphology and colour for males. The difference in length between the 2nd and 3rd phalanxes of the 3rd finger should be discarded as diagnostic trait between <em>P. pipistrellusem> and <em>P. pygmaeusem> in Croatia. Riassunto Identificazione su basi morfologiche del pipistrello pigmeo (<em>Pipistrellus pygmeausem>, Leach, 1825 in Croazia. A seguito della descrizione di due differenti "tipi fonici" nel pipistrello nano (<em>Pipistrellus pipistrellusem> e della successiva conferma su basi genetiche dell'esistenza di due specie distinte, designate come pipistrello nano (<em>P. pipistrellusem> e pipistrello pigmeo (<em>P. pygmaeusem>, la distinzione delle due specie in base a caratteristiche morfologiche esterne si è dimostrata un problema di difficile soluzione. Sulla base delle caratteristiche distintive e delle differenze biometriche proposte da altri Autori, sono state esaminate due colonie di pipistrello pigmeo a Donji Miholjac, in Croazia. I risultati ottenuti evidenziano che, tra tutti i potenziali caratteri sinora proposti, solo due risultano utili per un'identificazione diretta sul campo: la venatura delle ali, risultata utile alla discriminazione nell'89% degli esemplari analizzati, e la colorazione e morfologia del pene nei maschi. La

  13. Helminth communities of wood mouse (<em>Apodemus sylvaticusem> on the river Avena (Calabria, southern Italy

    Concetta Milazzo

    2011-02-01

    Full Text Available Helminth parasites of woodmouse <em>Apodemus sylvaticusem> were studied from May 1993 through to June 1994 on the River Avena (Calabria, southern Italy, which, as other Mediterranenan rivers, is dry for most of the year. Trapping sites were located in three different habitats of the river: slopes, shores and the riverbed. A total of 106 animals was captured and screened for the presence of helminths. Five endoparasitic species were detected: <em>Corrigia vittaem>, <em>Rictularia proniem>, <em>Heligmosomoides polygyrusem>, <em>Syphacia stromaem> and <em>S. fredericiem>. Four helminth species were recorded from the riverbed and shore sections, whereas only <em>H. polygyrusem> and <em>S. fredericiem> were found on the slopes. <em>Syphacia fredericiem> occurred at every trapping site. The total prevalence was 25.5% and total mean intensity was 27.2 parasites/mouse. No statistical significant difference was found for both the prevalence and mean intensity of infection between either habitats or sexes, suggesting that, from the point of view of the helminth community, the study area should be considered as a single habitat.

  14. Briareolate Esters from the Gorgonian <em>Briareum asbestinumem>

    Lyndon M. West

    2012-08-01

    Full Text Available Two new briarane diterpenoids briareolate esters J (1 and K (2 were isolated from the methanolic extract of the octocoral <em>Briareum> asbestinum em>collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2 showed weak growth inhibition activity against human embryonic stem cells (BG02.

  15. Feeding habits of the genet <em>Genetta genettaem> in an Iberian continental wetland

    Maite Sánchez; Patricia Rodrigues; Vicente Ortuño; Juan Herrero

    2009-01-01

    Abstract This study quantified the diet of the genet <em>Genetta genettaem> in an Iberian continental wetland, the Galachos Nature Reserve, northern Spain, based on the frequency with which items appeared in five monthly-surveyed latrines during 2004-2005. Prey types were identified <em>de visuem> using identification keys and expert advice. the genet was confirmed as an opportunistic and generalist predator, its diet including mam...

  16. Butylated Hydroxytoluene Analogs: Synthesis and Evaluation of Their <em>Multipotent em>Antioxidant Activities

    Wageeh A. Yehye

    2012-06-01

    Full Text Available A computer-aided predictions of antioxidant activities were performed with the Prediction Activity Spectra of Substances (PASS program. Antioxidant activity of compounds 1, 3, 4 and 5 were studied using 1,1-diphenyl-2-picrylhydrazyl (DPPH and lipid peroxidation assays to verify the predictions obtained by the PASS program. Compounds 3 and 5 showed more inhibition of DPPH stable free radical at 10−4 M than the well-known standard antioxidant, butylated hydroxytoluene (BHT. Compound 5 exhibited promising <em>in> <em>vitro> inhibition of Fe2+-induced <em>lipid peroxidationem> of the essential egg yolk as a lipid-rich medium<em> em>(83.99%, IC50 16.07 ± 3.51 µM/mL compared to a-tocopherol (a-TOH, 84.6%, IC50 5.6 ± 1.09 µM/mL. The parameters for drug-likeness of these BHT analogues were also evaluated according to the Lipinski’s “rule-of-five” (RO5. All the BHT analogues were found to violate one of the Lipinski’s parameters (Log<em>P> > 5, even though they have been found to be soluble in protic solvents. The predictive polar surface area (PSA and absorption percent (% ABS data allow us to conclude that they could have a good capacity for penetrating cell membranes. Therefore, one can propose these new multipotent antioxidants (MPAOs as potential antioxidants for tackling <em>oxidative stressem> and <em>lipid peroxidation processes.em>> em>

  17. Imaginary Jews and True Confessions: Ethnicity, Lyricism, and John Berryman's <em>Dream Songsem>

    Andrew S. Gross

    2009-01-01

    Berryman was fascinated with the figure of "the imaginary Jew." The phrase is the title of his first short story, it recurs in <em>The Dream Songsem>, and it was to have been the topic of the final chapter of his autobiographical novel <em>Recovery>. Critics have not treated Berryman's "imaginary Jew" kindly. Early critics saw prosopopoeia as uncongenial to the confessional project. More recent critics see the figure as a misappropriation of Jewish ident...

  18. Saponins with Neuroprotective Effects from the Roots of <em>Pulsatilla cernuaem>

    Wen-Hao Fan; Zong-Gui Yu; Hui Zhang; Yong-Nan Xu; Li-Bo Zou; Yi-Xia Gong; Hui-Ming Hua; Jian-Yu Liu; Ying-Li Guan

    2012-01-01

    Four new oleanene-type triterpenoid saponins together with six known saponins were isolated from the roots of <em>P>ulsatilla cernuaem> and their structures were elucidated on the basis of spectroscopic data, including 2D NMR spectra and chemical evidence. Among these one of the aglycones (gypsogenin) is reported for the first time from this genus. Some of these compounds showed significant neuroprotective effects against the

  19. Karyotypes of <em>Nannospalax> (Palmer 1903) populations (Rodentia: Spalacidae) from centraleastern Anatolia, Turkey

    Yüksel Coskun; Servet Ulutürk; Alaettin Kaya

    2010-01-01

    Riassunto
    Cariotipi di <em>Nannospalax> (Palmer 1903) (Rodentia, Spalacidae) dell’Anatolia centro-orientale, Turchia
    Sono stati analizzati i cariotipi di 20 (11 maschi e 9 femmine) <em>Nannospalax> catturati, nel periodo 2006-2009, in 11 località dell’Anatolia centro-orientale (Turchia). Sono state individuate sei diverse forme cromosomiche (2n=49; 2...

  20. Free Radical Scavenging, Antimicrobial and Immunomodulatory Activities of <em>Orthosiphon stamineusem>

    Nabil S. Harmal

    2012-05-01

    Full Text Available <em>Orthosiphon stamineus em>is considered an important traditional folk medicine. In this study ethanol and aqueous extracts of <em>O. stamineusem> were evaluated<em> in vitro em>for their antioxidant, antimicrobial as well as for their immunomodulatory properties on human peripheral blood mononuclear cells (PBMCs. The DPPH radical scavenging method was used for the determination of antioxidant activity, while the antibacterial efficacy was investigated by both disc diffusion method and Minimum Inhibitory Concentration (MIC against four bacterial strains (Gram-positive and Gram-negative. Furthermore, the immunomodulatory potential of the extracts was investigated through the MTT assay. Aqueous extract of <em>O. stamineusem> exhibited significant free radical scavenging activity with IC50 9.6 µg/mL, whereas the IC50 for the ethanol extract was 21.4 µg/mL. The best antimicrobial activity was shown by the aqueous extract of <em>O. stamineus em>against <em>Staphylococcus aureusem>, with inhibition zone of 10.5 mm and MIC value 1.56 mg/mL. Moreover, the results observed from the MTT assay showed that both plant extracts stimulated the PBMCs proliferation<em> in vitroem> in a concentration-dependent manner, but the aqueous extract has remarkable activity against PBMCs. These findings indicate that <em>O. stamineusem> showed high antioxidant activity and may be considered as an immunomodulatory agent.

  1. Variabilità morfologica ed ecologica in <em>Neomys fodiensem> e <em>Neomys anomalusem> nell'Appennino settentrionale

    Dino Scaravelli

    2003-10-01

    Full Text Available I due <em>Neomys> italiani sono ancora da chiarire dal punto di vista della loro caratterizzazione morfologica e ecologica. Il lavoro prende in considerazione un campione di entrambe le specie proveniente da habitat forestali dell?Appennino settentrionale per i quali sono stati identificati i principali parametri ambientali. Vengono quindi descritte la variabilità dei tratti morfologici delle due specie in aree localizzate nel Parco Nazionale Foreste Casentinesi, Monte Falterona e Campigna nell?Appennino tosco-romagnolo. Risultano di sicuro effetto discriminatorio la maschera facciale, il rapporto piede posteriore/coda e i caratteri cranici. Sulla base dei criteri identificativi si sono realizzate rilevazioni di misure corporee per le due specie e una comparazione degli habitat utilizzati. <em>N. fodiensem> appare unica specie nelle faggete-abetine e dominante nei castagneti, mentre nell?Ontaneta e nelle zone aperte e termofile si registra la sola presenza di <em>N. anomalusem>. Mancano entrambi nei prati cespugliati, nella pecceta e nella cerreta. I gradienti presenti sono quindi illustrati. Non appare una differenza altitudinale nel campione esaminato, posto in stazioni tra i 400 e i 1300 m, ma per entrambe vi sono maggiori riscontri nella fascia tra 700 e 850 m. Nell?analisi multivariata rispetto alle altre specie e alle variabili ambientali si riscontra sempre una discreta correlazione con la presenza di acqua di una certa ampiezza, che comunque è significativa solo per <em>N. fodiensem>, mentre risulta di interesse la positiva correlazione di <em>N. anomalusem> con <em>Apodemus sylvaticusem>.

  2. Manejo da podridão-de-Sclerotium em pimentão em um argisolo no Amazonas Southern blight management of bell pepper in an argissol in the Amazonas State

    Rosalee Albuquerque Coelho Netto

    2013-09-01

    Full Text Available A podridão-de-Sclerotium é uma doença comum em plantas da família Solanaceae na Amazônia. Visando avaliar estratégias de manejo para esta doença em pimentão (Capsicum annuum, L. Solanaceae, foi conduzido experimento em campo em blocos casualizados com parcelas subdivididas e seis repetições, em Argissolo Vermelho-Amarelo artificialmente infestado com Sclerotium rolfsii. O tratamento principal foi a cobertura do solo (cobertura do solo com serragem ou solo nu. Os tratamentos secundários consistiram na adição ao solo de: 1 composto vegetal (3 L por cova, 2 arroz colonizado com Trichoderma harzianum (90 g por cova contendo ≈ 1,4 x 10(9 conídios g-1, 3 composto vegetal e T. harzianum nas mesmas proporções descritas anteriormente e 4 testemunha. Todas as plantas receberam apenas adubação orgânica com composto vegetal na proporção de 1,5 L por cova, exceto as dos tratamentos com 3 L de composto por cova. A parcela principal foi constituída de três fileiras com dez plantas de pimentão (0,50 x 1,0 m e cada subparcela continha três fileiras com cinco plantas. A incidência da podridão-de-Sclerotium foi avaliada duas vezes por semana. A cobertura morta favoreceu significativamente a ocorrência da doença. Nas parcelas com esse tratamento o aumento da intensidade da doença, expressa em área abaixo da curva de progresso da doença (AACPD, foi 35,5% maior, em comparação com as parcelas sem cobertura morta. A aplicação de T. harzianum ou o incremento na quantidade de composto (de 1,5 para 3 L por cova reduziu a AACPD em 38,1% e 37,5%, respectivamente. A aplicação de T. harzianum ou o incremento na quantidade de composto, mesmo nos tratamentos com cobertura morta, reduziu significativamente a AACPD em 52,8% e em 55,1%, respectivamente, em comparação com o tratamento apenas com cobertura morta. Esses resultados sugerem que a utilização de T. harzianum e o aumento na quantidade de composto por cova são estrat

  3. Atividade de glutationa S-transferase na metabolização de acetochlor, atrazine e oxyfluorfen em milho (<em>Zea maysem> L.), sorgo (<em>Sorghum bicolorem> L.) e trigo (<em>Triticum aestivumem> L.) (Poaceae) Glutathione S-transferase activity in acetochlor, atrazine and oxyfluorfen metabolization in maize (<em>Zea maysem> L.), sorghum (<em>Sorghum bicolorem> L.) and wheat (<em>Triticum aestivumem>L.) (Poaceae)

    Ethel Lourenzi Barbosa Novelli; José Claudionir Carvalho; Guilherme Fernando Gomes Déstro; Karina Luiz Chamma; Leonardo César Ferreira; Ana Catarina Cataneo

    2002-01-01

    Este experimento foi conduzido para avaliar a seletividade em plantas dos herbicidas acetochlor, atrazine e oxyfluorfen em relação à atividade da glutationa S-transferase (GST) em plantas de milho (Zea mays L.), sorgo (Sorghum bicolor L.) e trigo (Triticum aestivum L.) (Poaceae). A atividade da GST foi detectada às 24, 48 e 72 horas após as aplicaç��es dos tratamentos. Os tratamentos do experimento consistiram de aplicação com água (controle), acetochlor (3 L.ha-1), atrazine (4 L.ha-1) e oxyf...

  4. Encapsulation-Induced Stress Helps <em>Saccharomyces cerevisiae em>Resist Convertible Lignocellulose Derived Inhibitors

    Johan O. Westman

    2012-09-01

    Full Text Available The ability of macroencapsulated <em>Saccharomyces cerevisiae em>CBS8066<em> em>to withstand readily and not readily <em>in situem> convertible lignocellulose-derived inhibitors was investigated in anaerobic batch cultivations. It was shown that encapsulation increased the tolerance against readily convertible furan aldehyde inhibitors and to dilute acid spruce hydrolysate, but not to organic acid inhibitors that cannot be metabolized anaerobically. Gene expression analysis showed that the protective effect arising from the encapsulation is evident also on the transcriptome level, as the expression of the stress-related genes <em>YAP1em>, <em>ATR1em> and <em>FLR1em> was induced upon encapsulation. The transcript levels were increased due to encapsulation already in the medium without added inhibitors, indicating that the cells sensed low stress level arising from the encapsulation itself. We present a model, where the stress response is induced by nutrient limitation, that this helps the cells to cope with the increased stress added by a toxic medium, and that superficial cells in the capsules degrade convertible inhibitors, alleviating the inhibition for the cells deeper in the capsule.

  5. Damage caused by <em>Skrjabingylus nasicolaem> (Leuckart, 1842), Metastrongylidae, to weasels (<em>Mustela nivalisem> L.) in North-Western Italy

    Claudio Prigioni; Anna Boria

    1995-01-01

    Abstract The percentage of infestation (incidence) and the degree of damage caused by <em>Skrjabingylus nasicolaem> were analysed in 15 fresh skulls of weasels (<em>Mustela nivalisem>) collected in Pavia province (Northern Italy) during 1986-89 and in 79 preserved skulls from the Civic Museum of Natural History of Genoa (Liguria region). The incidence was 66.6% for the first sample of weasels and 54.4% for the second one; the mean degr...

  6. Lectin from <em>Canavalia brasiliensisem> Seeds (ConBr Is a Valuable Biotechnological Tool to Stimulate the Growth of <em>Rhizobium tropiciem> <em>in Vitroem>

    Ricardo Pires dos Santos

    2012-05-01

    Full Text Available To study the interactions between a <em>Rhizobium tropiciem> strain and lectins isolated from the seeds of <em>Canavalia ensiformisem> (ConA and <em>Canavalia brasiliensisem> (ConBr, a lectin fluorescence assay was performed. In addition, an experiment was designed to evaluate the effect of the two lectins on bacterial growth. Both lectins were found to bind to <em>R. tropiciem> cells, but the interactions were inhibited by D-mannose. Interestingly, only ConBr stimulated bacterial growth in proportion to the concentrations used (15.6–500 µg/mL, and the bacterial growth stimulation was inhibited by D-mannose as well. Structure/Function analyses by bioinformatics were carried out to evaluate the volume and carbohydrate recognition domain (CRD configuration of ConA and ConBr. The difference of spatial arrangement and volume of CRD may indicate the variation between biological activities of both lectins. The results suggest that ConBr could be a promising tool for studies focusing on the interactions between rhizobia and host plants.

  7. Altitudinal distribution of the common longeared bat <em>Plecotus auritusem> (Linnaeus, 1758 and grey long-eared bat <em>Plecotus austriacusem> (J. B. Fischer, 1829 (Chiroptera, Vespertilionidae in the Tatra mountains (southern Poland

    Krzysztof Piksa

    2006-03-01

    Full Text Available Riassunto Distribuzione altitudinale di Orecchione bruno (<em>Plecotus auritusem> e Orecchione meridionale (<em>Plecotus austriacusem> nei Monti Tatra (Polonia meridionale. Vengono riportati nuovi dati relativi alla distribuzione altitudinale nei Monti Tatra (Polonia meridionale di <em>Plecotus auritusem> e <em>P. austriacusem>. Tali segnalazioni incrementano le conoscenze relative alla presenza di questi chirotteri a quote elevate, in particolare per la Polonia. In inverno <em>P. auritusem> è stato rinvenuto a 1921 m s.l.m. mentre in estate è stato rinvenuto a 2250 m s.l.m.; in aggiunta, sono stati ritrovati resti ossei a 1929 m s.l.m. <em>P. austriacusem> è stato segnalato in ibernazione a 1294 m s.l.m.

  8. Isolation and Characterization of 46 Novel Polymorphic EST-Simple Sequence Repeats (SSR Markers in Two Sinipercine Fishes<em> em>(Siniperca> and Cross-Species Amplification

    Liang Cao

    2012-07-01

    Full Text Available With the development of next generation sequencing technologies, transcriptome level sequence collections are emerging as prominent resources for the discovery of gene-based molecular markers. In this study, we described the isolation and characterization of 46 novel polymorphic microsatellite loci for <em>Siniperca chuatsiem> and <em>Siniperca scherzeriem> from the transcriptome of their F1 interspecies hybrids. Forty-three of these loci were polymorphic in <em>S. chuatsiem>, and 20 were polymorphic in <em>S. scherzeriem>. In <em>S. chuatsiem>, the number of alleles per locus ranged from 2 to 8, and the observed and expected heterozygosities varied from 0.13 to 1.00 and from 0.33 to 0.85, respectively. In <em>S. scherzeriem>, the number of alleles per locus ranged from 3 to 9, and the observed and expected heterozygosities varied from 0.19 to 1.00 and from 0.28 to 0.88, respectively. We also evaluated the cross-amplification of 46 polymorphic loci in four species of sinipercine fishes: <em>Siniperca kneriem>, <em>Siniperca undulataem>, <em>Siniperca obscuraem>, and <em>Coreoperca whiteheadiem>. The interspecies cross-amplification rate was very high, totaling 94% of the 184 locus/taxon combinations tested. These markers will be a valuable resource for population genetic studies in sinipercine fishes.

  9. OCCURENCE OF Salmonella IN CHICKEN CARCASSES AND CUTS COMMERCIALIZED IN GOIÂNIA-GO OCORRÊNCIA DE Salmonella EM CARCAÇAS E CORTES DE FRANGOS COMERCIALIZADOS EM GOIÂNIA-GO

    Iolanda Aparecida Nunes

    2007-09-01

    Full Text Available

    Its was analised 53 chicken carcasses and commercial cuts acquired in supermarkets of Goiânia-GO aiming to isolate <em>Salmonella>. The contamination rate was 13.2% and serotypes <em>S. brandenburgem>, <em>S. typhimuriumem>, <em>S. agonaem>, <em>S. derbyem> and <em>S. hadorem> were identified.

    KEY-WORDS: <em>Salmonella>; chicken; chicken carcasses; commercial cuts.

    No presente estudo foram analisadas, com vistas ao isolamento de <em>Salmonella>, 53 amostras de carcaças e cortes comerciais de frangos colhidas em supermercados e casas de carnes de Goiânia - GO. Observou-se freqüência média do patógeno de 13,2%, sendo identificados os sorotipos <em>E. brandenburgem>, <em>S. typhimuriumem>, <em>S.> <em>agona>, <em>S. derbyem> e <em>S. Hadarem>.

    PALAVRAS-CHAVE: <em>Salmonella>; frango de corte; carcaça; cortes comerciais.

  10. Chemical Composition and Biological Activities of the Essential Oils from <em>Duguetia lanceolataem> St. Hil. Barks

    Maria A. C. Kaplan

    2012-09-01

    Full Text Available Essential oils of <em>Duguetia lanceolataem> barks, obtained at 2 (T2 and 4 h (T4, were identified by gas chromatography and gas chromatography/mass spectrometry. β-Elemene (12.7 and 14.9%, caryophyllene oxide (12.4 and 10.7% and β-selinene (8.4 and 10.4% were the most abundant components in T2 and T4, respectively. The essential oils inhibited the growth of <em>Staphylococcus aureusem>,> Streptococcus pyogenesem>, <em>Escherichia coliem> and <em>Candida albicansem>. The essential oils were cytotoxic against brine shrimp. The extraction time influenced the chemical composition and biological activities of essential oils obtained from the barks of <em>D. lanceolataem>.

  11. DOE/EM Criticality Safety Needs Assessment

    Westfall, Robert Michael [ORNL; Hopper, Calvin Mitchell [ORNL

    2011-02-01

    The issue of nuclear criticality safety (NCS) in Department of Energy Environmental Management (DOE/EM) fissionable material operations presents challenges because of the large quantities of material present in the facilities and equipment that are committed to storage and/or material conditioning and dispositioning processes. Given the uncertainty associated with the material and conditions for many DOE/EM fissionable material operations, ensuring safety while maintaining operational efficiency requires the application of the most-effective criticality safety practices. In turn, more-efficient implementation of these practices can be achieved if the best NCS technologies are utilized. In 2002, DOE/EM-1 commissioned a survey of criticality safety technical needs at the major EM sites. These needs were documented in the report Analysis of Nuclear Criticality Safety Technology Supporting the Environmental Management Program, issued May 2002. Subsequent to this study, EM safety management personnel made a commitment to applying the best and latest criticality safety technology, as described by the DOE Nuclear Criticality Safety Program (NCSP). Over the past 7 years, this commitment has enabled the transfer of several new technologies to EM operations. In 2008, it was decided to broaden the basis of the EM NCS needs assessment to include not only current needs for technologies but also NCS operational areas with potential for improvements in controls, analysis, and regulations. A series of NCS workshops has been conducted over the past years, and needs have been identified and addressed by EM staff and contractor personnel. These workshops were organized and conducted by the EM Criticality Safety Program Manager with administrative and technical support by staff at Oak Ridge National Laboratory (ORNL). This report records the progress made in identifying the needs, determining the approaches for addressing these needs, and assimilating new NCS technologies into EM

  12. Terpene Glycosides from the Roots of <em>Sanguisorba officinalisem> L. and Their Hemostatic Activities

    Wei Sun; Zi-Long Zhang; Xin Liu; Shuang Zhang; Lu He; Zhe Wang; Guang-Shu Wang

    2012-01-01

    Guided by a hemostasis bioassay, seven terpene glycosides were isolated from the roots of <em>Sanguisorba officinalisem> L. by silica gel column chromatography and preparative HPLC. On the grounds of chemical and spectroscopic methods, their structures were identified as citronellol-1-<em>O>-α-l-arabinofuranosyl-(1→6)-β-d-glucopyranoside (1), geraniol-1-<em>O>-α-l-arabinofuranosyl-(1→6)-β-d-glucopyranoside (

  13. Brasil em obras, peões em luta, sindicatos surpreendidos

    Roberto Véras

    2014-05-01

    Full Text Available O presente artigo aborda as revoltas e greves ocorridas em março de 2011 em canteiros de obras do Programa de Aceleração do Crescimento (PAC, do Governo Federal, que alcançou grande repercussão nacional. Tem como foco os conflitos e as negociações, envolvendo trabalhadores, sindicatos, empresários, Governo, Justiça, Ministério Público do Trabalho, entre outros atores, estabelecidos durante a construção das Usinas Hidroelétricas de Jirau e Santo Antônio, situadas no Norte do país. Visou identificar as posições dos referidos atores e, sob uma perspectiva sociológica, propor reflexões sobre as potencialidades e os limites da atividade sindical. Que questões trouxeram tais acontecimentos ao sindicalismo, quanto às relações deste, de um lado, com suas próprias bases e, de outro, com o atual projeto governamental?

  14. Burnout em residentes de enfermagem

    Gianfábio Pimentel Franco; Alba Lúcia Bottura Leite de Barros; Luiz Antônio Nogueira-Martins; Sandra Salloum Zeitoun

    2011-01-01

    Enfermeiros Residentes podem experimentar desgaste físico e emocional decorrentes do cotidiano da Residência de Enfermagem. O objetivo deste estudo foi determinar a incidência do Burnout em Residentes de Enfermagem. Realizou-se um estudo exploratório, descritivo, analítico e longitudinal-prospectivo com 16 Residentes, no período de dois anos. Utilizou-se o Maslach Burnout Inventory traduzido e validado para o Brasil e um instrumento de dados sociodemográficos/ocupacionais. Dos Residentes, 17....

  15. Dinâmica da institucionalização de idosos em Belo Horizonte, Brasil Dynamics of institutionalization of older adults in Belo Horizonte, Brazil

    Flávio Chaimowicz

    1999-10-01

    Full Text Available OBJETIVO: O processo de envelhecimento populacional brasileiro tem sido acompanhado por transformações epidemiológicas e sociais que, em outros países, aumentaram a demanda por instituições de longa permanência. Nesse sentido, desenvolveu-se estudo sobre dinâmica da institucionalização de idosos através da análise da oferta de leitos e características demográficas dos residentes em asilos. MÉTODOS: Foi realizado levantamento dos asilos de idosos do Município de Belo Horizonte, MG. Foram registradas datas de nascimento e admissão de 1.128 residentes de 33 dos 40 asilos em funcionamento no município. A lotação foi calculada através da capacidade informada e da taxa de institucionalização, segundo dados da Pesquisa Nacional por Amostra de Domicílios (PNAD. RESULTADOS: As taxas de institucionalização de idosos (65+ do município foram 0,9% (mulheres e 0,3% (homens. A lotação mediana dos asilos era de 92%. Dentre os 1.128 residentes arrolados (92,5% do total, as mulheres (81% apresentavam maiores médias de idade (76,4 x 70,4 anos; p=0,00 e estada (5,6 x 4,5 anos; p=0,01. DISCUSSÃO/CONCLUSÕES: Elevada lotação, listas de espera nos asilos filantrópicos (85% do total e rígidos critérios para admissão (metade recusava idosos demenciados ou dependentes sugerem que a baixa taxa de institucionalização se deve à escassez de vagas. A predominância de idosas reflete a prevalência de viúvas ou separadas na comunidade (66% contra 76% de homens casados. A proporção de homens adultos (31% INTRODUCTION: Epidemiological and social changes related to population aging in Brazil will probably increase the need for nursing homes (NH. The study analyses the dynamics of institutionalization in Belo Horizonte, a 3 million inhabitant city of whom 8.0% are aged 60 or more. METHODS: Age and length of stay of 1,128 NH residents (92.5% of the estimated population was registered and occupancy and institutionalization rates were

  16. Il ruolo dell'Arvicola delle nevi <em>Chionomys nivalisem> come specie-preda: un'analisi della situazione italiana

    Armando Nappi

    2003-10-01

    Full Text Available L?Arvicola delle nevi <em>Chionomys nivalisem>, a causa della sua particolare nicchia ecologica costituita, nella sua componente spaziale, dai suoli pietrosi nei cui interstizi vive, viene di norma considerata una preda poco rappresentata nelle catene trofiche. In Italia, eccettuato un dato incerto di cattura da <em>Buteo buteoem>, è risultata predata da cinque specie di serpenti (<em>Coronella austriacaem>, <em>Elaphe longissimaem>, <em>Vipera aspisem>, <em>V. berusem>, <em>V. ursiniiem>, sei di uccelli (<em>Aquila chrysaetosem>, <em>Strix alucoem>, <em>Bubo buboem>, <em>Aegolius funereusem>, <em>Asio otusem> e cinque di mammiferi (<em>Vulpes vulpesem>, <em>Mustela nivalisem>, <em>M. ermineaem>, <em>Martes> sp., <em>Felis catusem>. In alcuni casi, come in <em>Vipera berusem> a Passo Fedaia (BL, <em>Asio otusem> a S. Valentino alla Muta (BZ, <em>Mustela ermineaem> nel Parco Naturale Adamello-Brenta (TN con percentuali piuttosto consistenti, rispettivamente del 69.6%, 60.71% e 35.89%. In uno studio su <em>Vulpes vulpesem> nel Parco Nazionale Gran Paradiso (TO-AO è risultata essere la preda dominante tra i roditori. Sempre nella stessa area, è interessante la predazione da <em>Aegolius funereusem> per la quale risulta, dopo <em>Clethrionomys glareolusem>, la preda più rappresentata (27.97% malgrado, da uno studio di trappolamento di micromammiferi effettuato intorno all?area di nidificazione, risulti assente rivelando così un comportamento esplorativo del rapace diretto proprio alla ricerca dell?arvicola delle nevi. Da una prima analisi sembrerebbe dunque da rivalutare il ruolo di questo roditore come preda, anche considerando il contributo in biomassa che può rappresentare. Su un totale di 184 dati reperiti sulla presenza della specie in Italia, 28 (15.2% derivano da residui di predazione. Benché non risulti un quantitativo alto comparato ad altri micromammiferi è comunque significativo

  17. Bioassay-Guided Antidiabetic Study of <em>Phaleria macrocarpaem> Fruit Extract

    Mohd Z. Asmawi

    2012-04-01

    Full Text Available An earlier anti-hyperglycemic study with serial crude extracts of <em>Phaleria macrocarpaem> (PM fruit indicated methanol extract (ME as the most effective. In the present investigation, the methanol extract was further fractionated to obtain chloroform (CF, ethyl acetate (EAF, <em>n>-butanol (NBF and aqueous (AF fractions, which were tested for antidiabetic activity. The NBF reduced blood glucose (<em>p> < 0.05 15 min after administration, in an intraperitoneal glucose tolerance test (IPGTT similar to metformin. Moreover, it lowered blood glucose in diabetic rats by 66.67% (<em>p> em>< 0.05, similar to metformin (51.11%, glibenclamide (66.67% and insulin (71.43% after a 12-day treatment, hence considered to be the most active fraction. Further fractionation of NBF yielded sub-fractions I (SFI and II (SFII, and only SFI lowered blood glucose (<em>p em>< 0.05, in IPGTT similar to glibenclamide. The ME, NBF, and SFI correspondingly lowered plasma insulin (<em>p em>< 0.05 and dose-dependently inhibited glucose transport across isolated rat jejunum implying an extra-pancreatic mechanism. Phytochemical screening showed the presence of flavonoids, terpenes and tannins, in ME, NBF and SFI, and LC-MS analyses revealed 9.52%, 33.30% and 22.50% mangiferin respectively. PM fruit possesses anti-hyperglycemic effect, exerted probably through extra-pancreatic action. Magniferin, contained therein may be responsible for this reported activity.

  18. Dois funcionalistas franceses em confronto

    Rafael Eugenio Hoyos-Andrade

    2001-02-01

    Full Text Available

    Comparamos, neste artigo, de modo aproximativo e provisório, dois modelos de análise sintática e dois métodos de representação gráfica dessas análises: trata-se dos modelos e métodos de André Martinet e Lucien Tesnière. Depois de algumas considerações introdutórias relativas ao funcionalismo dos autores em causa, arrolamos um conjunto de características que aproximam ou opõem os seus respectivos modelos. Apresentamos, em seguida, no intuito de beneficiar os estudantes universitários de sintaxe, as representações gráficas de um mesmo enunciado segundo o método estemático de Tesnière e segundo o método de visualização das relações sintáticas de Martinet, para concluir que os dois modelos/métodos, embora diferentes, poderiam eventualmente ser integrados num único sistema de análise e representação.

  19. O MAL EM ERIC WEIL

    Daniel Benevides Soares

    2014-12-01

    Full Text Available O mal ocupa a condição de problema para a filosofia desde a Antiguidade. Passando pelas ponderações dos estóicos e de Santo Agostinho, tratado no contexto da teodiceia por Leibniz, o mal aporta como objeto de preocupação para a moral em Kant. Muito conhecido por sua definição como um kantiano pós-hegeliano, é com Kant, mas indo além dele que Weil trata do mal, pensando-o como formas de violência. Considerada como o outro do sentido e da razão, a violência se manifesta de maneiras variadas. Nosso intuito é determinar o conceito de mal em Eric Weil enquanto forma de violência. Para isso, nos propomos a situar no esquema conceitual da violência duas formas de mal discutidas por Weil nos seus textos: o mal radical e o mal diabólico.

  20. Ser marrano em Minas Colonial

    Anita Novinsky

    2001-01-01

    Full Text Available Baseado em 57 Processos inéditos de marranos (cristãos-novos, conversos presos em Minas Gerais no século XVIII, este artigo procura mostrar seu papel na Idade de Ouro do Brasil. 64% deles eram mercadores e 23% eram mineiros. Pertenciam à classe média e raros eram os magnatas. Nenhum dele esteve envolvido no tráfico negreiro. Acusados do crime de judaísmo e de pertencerem a sociedades secretas, representaram 42% dos brasileiros condenados à morte. Ser marrano entre os portugueses no Brasil mais um sentimento e uma visão de mundo do que uma prática religiosa.Based on 57 unknown trials of marranos (new christians, conversos arrested by the Inquisition in Minas Gerais in the XVIII the century, this article shows their role in shapping the history of Minas Gerais. 64% of them were merchants na 23% were miners. Most of them belonged to a middle class and rare were those whit great fortunes. No one of them were engaged in slave trade. Acused of judaism and of participating in secret society the marranos of Minas represented 42% of the Brazilian burned at the stake. Being a marrano in Minas Gerais was not always being a crypto-new. Marranism in Brasil was a feeling and a approach to life.

  1. Terapia breve em hospital fechado

    Paulo Cesar Sandler

    1978-09-01

    Full Text Available O presente estudo cuida de pacientes "difíceis" da clínica psiquiátrica e psicoterápica: os pacientes que apresentam o fenômeno da atuação, cuja aproximação terapêutica tem se demonstrado problemática, mesmo com o advento das modernas técnicas de psicoterapia e das comunidades terapêuticas. Os diagnósticos psiquiátricos destes pacientes variam: são neuróticos, apresentam transtornos de pesonalidade, são psicóticos e quase sempre com graves doenças secundárias: alcoolismo e toxicomania (Códigos Classificação Internacional de Doenças 295 a 299, 300. 301, 303 e 304. Propõe-se, à luz da compreensão psicanalítica destas pessoas, um tratamento psicoterápico breve, focal, com o auxílio de uma hospitalização em regime fechado. Para a avaliação dos resultados do método psicoterápico diádico, criaram-se critérios de cura coerentes com a proposta terapêutica, e equiparam-se estes critérios clínicos a valores numéricos. Utilizando 36 pacientes internados, verificou-se até que ponto eles alcançavam estes critérios. Cada paciente recebeu um escore - valor numérico - que expressou o seu desempenho durante o tratamento em regime de internação, e sua conduta pós-alta hospitalar, durante um seguimento médio de 21 meses. Estes 36 pacientes puderam ser divididos em dois grupos: os de evolução favorável (obtivemos 36,1% e os de evolução desfavorável. Por meio de uma amostra sistemática composta por 41 pacientes que não foram submetidos ao método, internados no mesmo período de tempo, no mesmo hospital, e pareados com nossa casuística, fêz-se uma comparação estatística entre os percentis obtidos nas evoluções dos dois grupos. O valor do teste estatístico, o chi quadrado, não foi significante. O exame das proporções correspondentes a cada patologia em separado sugeriu fortemente que o tratamento estaria indicado nas neuroses e nas psicoses, mas que seria realmente ineficaz nos transtornos de

  2. Alimentazione di <em>Marmota marmotaem> in praterie altimontane delle dolomiti bellunesi

    Alessandro Rudatis

    2006-03-01

    Full Text Available Abstract The diet of <em>Marmota marmotaem> in the mountain prairie of south-eastern Italian Alps. Diet composition of two family groups of alpine marmots was investigated in two areas of the Agordino’s Dolomites (Italian Alps in June-September 2001, by means of microscopic analysis of faeces and of direct observation of feeding activity. During the whole period of activity, a high consume of Angiosperms was confirmed, especially plants in flower; among them the “graminoids” seemed to play an important role only during the initial part of the active period. Generally vegetative parts predominated over flowers. The ingestion of animal preys was not confirmed by the analysis of droppings. Comparing diet composition of the two groups, Graminaceae (<em>Poa>, <em>Phleum>, Compositae (<em>Achillea>, Cyperaceae/Juncaceae, Leguminosae (<em>Anthyllis>, Rosaceae, and Labiatae (<em>Prunella>, <em>Stachys> formed the bulk of marmot diet in the study areas. Diet showed low diversity considering the abundance of plant species in the surrounding environment. Food resources were probably used in relation to their easy digestibility, with a high content in proteins, sugar and water. The knowledge of vegetation features in relation to marmot trophic habits can represent a useful tool for the management of this species. Riassunto Il regime alimentare di due gruppi di Marmotta alpina è stato studiato in giugno-settembre 2001 in due aree delle Dolomiti agordine (SE Italia, attraverso l’analisi microscopica delle feci e l’osservazione diretta dell’attività alimentare. Durante tutto il periodo di attività si è notato un forte consumo di Angiosperme, specialmente piante a fiore, mentre le ”graminoidi” sembra giochino un ruolo importante all’inizio della stagione. In generale le parti vegetali predominano sui fiori. L’ingestione di prede animali non è stata

  3. Feeding tests on captive otters <em>Lutra lutraem>

    Elena Ferrario

    1995-12-01

    Full Text Available Abstract The study was carried out during 1990-91 in "La Torbiera" Faunistic Park (Piemonte region, northern Italy. Feeding experiments were conducted on 4 pairs of otters (<em>Lutra lutraem> of 2-7 year old, housed in enclosures of 210-360 m² in size with ponds of 20-33 m² and about 1 m in depth. Three foraging tests were done on a pair using eels <em>Anguilla anguillaem>, rainbow trout <em>Salmo gairdneriem> and roach <em>Rutilus erythrophthalmusem>, in order to collect data on dive duration and foraging success. Both parameters varied widely and were influenced by the behaviour of fish prey. For eels, slow moving fishes, the dive duration and the foraging success were lower than those of other fish species. Feeding correction factors, calculated as ratio between the weight of ingested fish and the dry weight of remains in spraints, were determined from a total of 21 experiments carried out on eels, rudd <em>Scardinius erythrophthalmusem> and bleak <em>Alburnus alburnus alborellaem>. The factors differed widely between the fish species and the highest value was found for eels. Riassunto Test alimentari sulla lontra <em>Lutra lutraem> in cattività - Lo studio è stato effettuato nel 1990-91 presso il Parco Faunistico "La Torbiera" di Agrate Conturbia (Novara, Piemonte. I test alimentari sono stati condotti su 4 coppie di lontra (<em>Lutra lutraem> di età compresa tra 2 e 7 anni, tenute in recinti di 210-360 m² provvisti di vasche di 20-33 m² profonde 1 m circa. Tre test sono stati effettuati su una coppia somministrando quantità note di Anguilla <em>Anguilla anguillaem>, Trota iridea <em>Salmo gairdneriem> e Triotto <em>Rutilus erythrophthalmusem>, al fine di valutare la durata delle immersioni e il successo di predazione. Entrambi i parametri variavano ampiamente tra le specie ittiche considerate ed erano influenzati dal comportamento delle stesse. Per l

  4. Elongation Factor 1β' Gene from <em>Spodoptera exiguaem>: Characterization and Function Identification through RNA Interference

    Li-Na Zhao

    2012-06-01

    Full Text Available Elongation factor (EF is a key regulation factor for translation in many organisms, including plants, bacteria, fungi, animals and insects. To investigate the nature and function of elongation factor 1β' from <em>Spodoptera> exiguaem> (SeEF-1β', its cDNA was cloned. This contained an open reading frame of 672 nucleotides encoding a protein of 223 amino acids with a predicted molecular weight of 24.04 kDa and pI of 4.53. Northern blotting revealed that <em>SeEF-1β'em> mRNA is expressed in brain, epidermis, fat body, midgut, Malpighian tubules, ovary and tracheae. RT-PCR revealed that <em>SeEF-1β'em> mRNA is expressed at different levels in fat body and whole body during different developmental stages. In RNAi experiments, the survival rate of insects injected with<em> SeEF-1β'em>> em>dsRNA was 58.7% at 36 h after injection, which was significantly lower than three control groups. Other elongation factors and transcription factors were also influenced when EF-1β' was suppressed. The results demonstrate that <em>SeEF-1β' em>is a key gene in transcription in <em>S. exiguaem>.

  5. Echolocation calls and morphology in the Mehelyi’s (<em>Rhinolophus mehelyiem> and mediterranean (<em>R. euryaleem> horseshoe bats: implications for resource partitioning

    Egoitz Salsamendi

    2006-03-01

    Full Text Available Abstract <em>Rhinolophus euryaleem> and <em>R. mehelyiem> are morphologically very similar species and their distributions overlap extensively in the Mediterranean basin. We modelled their foraging behaviour using echolocation calls and wing morphology and, assuming niche segregation occurs between the two species, we explored how it is shaped by these factors. Resting frequency of echolocation calls was recorded and weight, forearm length, wing loading, aspect ratio and wing tip shape index were measured. <em>R. mehelyiem> showed a significantly higher resting frequency than <em>R. euryaleem>, but differences are deemed insufficient for dietary niche segregation. Weight and forearm length were significantly larger in <em>R. mehelyiem>. The higher values of aspect ratio and wing loading and a lower value of wing tip shape index in <em>R. melehyiem> restrict its flight manoeuvrability and agility. Therefore, the flight ability of <em>R. mehelyiem> may decrease as habitat complexity increases. Thus, the principal mechanism for resource partitioning seems to be based on differing habitat use arising from differences in wing morphology. Riassunto Ecolocalizzazione e morfologia nei rinolofi di Mehely (<em>Rhinolophus mehelyiem> e euriale (<em>R. euryaleem>: implicazioni nella segregazione delle risorse trofiche. <em>Rhinolophus euryaleem> e <em>R. mehelyiem> sono specie morfologicamente molto simili, la cui distribuzione risulta largamente coincidente in area mediterranea. Il comportamento di foraggiamento delle due specie è stato analizzato in funzione delle caratteristiche dei segnali di ecolocalizzazione e della morfologia alare, ed è stata valutata l’incidenza di questi fattori nell’ipotesi di una segregazione delle nicchie. È stata rilevata la frequenza a riposo dei segnali ultrasonori, così come il peso, la lunghezza dell’avambraccio, il carico alare, e due

  6. Inhibition of <em>Burkholderia multivoransem> Adhesion to Lung Epithelial Cells by Bivalent Lactosides

    Trinidad Velasco-Torrijos

    2012-08-01

    Full Text Available <em>Burkholderia cepaciaem> complex (Bcc is an opportunistic pathogen in cystic fibrosis patients which is inherently resistant to antimicrobial agents. The mechanisms of attachment and pathogenesis of Bcc, a group of 17 species, are poorly understood. The most commonly identified Bcc species in newly colonised patients,<em> Burkholderia multivoransem>, continues to be acquired from the environment. Development of therapies which can prevent or reduce the risk of colonization on exposure to Bcc in the environment would be a better alternative to antimicrobial agents. Previously, it has been shown that Bcc strains bound to many glycolipid receptors on lung epithelia. Using a real-time PCR method to quantify the levels of binding of <em>B. multivoransem> to the lung epithelial cells, we have examined glycoconjugate derivatives for their potential to inhibit host cell attachment. Bivalent lactosides previously shown to inhibit galectin binding significantly reduced the attachment of <em>B. multivoransem> to CF lung epithelial cells at micromolar concentrations. This was in contrast to monosaccharides and lactose, which were only effective in the millimolar range. Development of glycoconjugate therapies such as these, which inhibit attachment to lung epithelial cells, represent an alternative means of preventing infection with inherently antimicrobially resistant pathogens such as <em>B. multivoransem>.

  7. Antioxidative Properties of Crude Polysaccharides from <em>Inonotus obliquusem>

    Jinyou Duan

    2012-07-01

    Full Text Available The mushroom <em>Inonotus obliquusem>> em>has been widely used as a folk medicine in Russia, Poland and most of the Baltic countries. In this study, water-soluble and alkali-soluble crude polysaccharides (IOW and IOA were isolated from <em>I. obliquusem>, and the carbohydrate-rich fractions IOW-1 and IOA-1 were obtained respectively after deproteination and depigmentation. Their contents, such as neutral carbohydrate, uronic acid and protein, were measured. Their antioxidant properties against chemicals-induced reactive species (ROS including 1,1'-Diphenyl-2-picrylhydrazyl (DPPH radical, hydroxyl radical and superoxide anion radical, as well as their protective effects on H2O2-induced PC12 cell death were investigated. Results showed that <em>I. obliquusem> polysaccharides can scavenge all ROS tested above in a dose-dependent manner. IOA and its product IOA-1 could rescue PC12 cell viability from 38.6% to 79.8% and 83.0% at a concentration of 20µg/mL. Similarly, IOW and its product IOW-1 at the same dose, can also increase cell viability to 84.9% and 88.6% respectively. The antioxidative activities of water-soluble and alkali-soluble polysaccharide constituents from <em>I. obliquusem> might contribute to diverse medicinal and nutritional values of this mushroom.

  8. Synthesis and Antibacterial Evaluation of New <em>N>-acylhydrazone Derivatives from Dehydroabietic Acid

    Wen Gu

    2012-04-01

    Full Text Available A series of new <em>N>-acylhydrazone derivatives were synthesized in good yields through the reactions of dehydroabietic acid hydrazide with a variety of substituted arylaldehydes. The structures of the synthesized compounds were confirmed by IR, 1H- and 13C-NMR, ESI-MS, elemental analysis and single crystal X-ray diffraction. From the crystal structure of compound 4l, the C=N double bonds of these <em>N>-acylhydrazones showed (<em>E>-configuration, while the NMR data of compounds 4aq indicated the existence of two rotamers for each compound in solution. The target compounds were evaluated for their antibacterial activities against four microbial strains. The result suggested that several compounds exhibited pronounced antibacterial activities. Particularly, compound 4p exhibited good antibacterial activity against <em>Staphylococcus aureusem> and <em>Bacillus subtilisem> comparable to positive control. The possible antibacterial metabolism and the strategy for further optimization of this compound were also discussed.

  9. Training for Defense? From Stochastic Traits to Synchrony in Giant Honey Bees (<em>Apis dorsataem>

    Gerald Kastberger

    2012-08-01

    Full Text Available In Giant Honey Bees, abdomen flipping happens in a variety of contexts. It can be either synchronous or cascaded, such as in the collective defense traits of shimmering and rearing-up, or it can happen as single-agent behavior. Abdomen flipping is also involved in flickering behavior, which occurs regularly under quiescent colony state displaying singular or collective traits, with stochastic, and (semi- synchronized properties. It presumably acts via visual, mechanoceptive, and pheromonal pathways and its goals are still unknown. This study questions whether flickering is preliminary to shimmering which is subject of the <em>fs em>(flickering-shimmering-transition> hypothesis? We tested the respective prediction that trigger sites (<em>ts> at the nest surface (where shimmering waves had been generated show higher flickering activity than the alternative non-trigger sites (<em>nts>. We measured the flickering activity of <em>ts>- and <em>nts>-surface bees from two experimental nests, before and after the colony had been aroused by a dummy wasp. Arousal increased rate and intensity of the flickering activity of both <em>ts>- and <em>nts> cohorts (P < 0.05, whereby the flickering intensity of <em>ts>-bees were higher than that of <em>nts>-bees (P < 0.05. Under arousal, the colonies also increased the number of flickering-active <em>ts>- and <em>nts>-cohorts (P < 0.05. This provides evidence that cohorts which are specialist at launching shimmering waves are found across the quiescent nest zone. It also proves that arousal may reinforce the responsiveness of quiescent curtain bees for participating in shimmering, practically by recruiting additional trigger site bees for expanding repetition of rate and intensity of shimmering waves. This finding confirms the <em>fs-transition> hypothesis and constitutes evidence that flickering is part of a basal colony-intrinsic information system

  10. NOVOS PARASITÓIDES EM OVOS DE Dirphia Araucariae (LEPIDOPTERA, ATTACIDAE NEW PARASITOIDS IN EGGS OF Dirphia araucariae (LEP.; ATTACIDAE

    Jácomo Divino Borges

    2007-09-01

    Full Text Available

    Foram observados novos parasitóides nos ovos de <em>Dirphia> <em>araucariae> Jones, 1908 (<em>Lepidoptera>, <em>Attacidae>. A porcentagem do parasitismo em ovos do hospedeiro, coletados na Fazenda Marabá, Município de Congonhinhas (PR foi de 20,71%, e as espécies de parasitóides identificadas e suas freqüências do: <em>Anastatus> <em>sp> (0,45%; <em>A. charitos em>De Santis, 1982 (1,08%; A. (<em>Proanastatus> <em>excavatus> (De Santis, 1952 (1,97%; <em>Ooencyrtus> <em>sp> (17,86%; <em>O.> <em>blastothricoide> De Santis, 1988 (43,65%; e <em>O. dirphiaeem> De Santis, 1988 (34,99%.

    PALAVRAS-CHAVE: <em>Anastatus> <em>spp>; <em>Araucaria> <em>angustifolia>; controle biológico; lagarta-da-araucária; <em>Ooencyrtus sppem>; pinheiro-do-Paraná.

    The parasitism in Dirphia araucariae Jones, 1908 (<em>Lepidoptera>, <em>Attacidae> was studied and the parasitoids observed on its eggs collected in 'Fazenda Marabá’, Municipality of Congonhinhas, State of Paraná, Brazil, were the following: <em>Anastatus> <em>sp>.; <em>A>. <em>charitos> De Santis, 1982; <em>A.> (<em>Proanastatus> <em>excavatus> (De Santis, 1952; <em>Ooencyrtus> <em>sp.>; <em>O. blastothricoideem> De Santis, 1988, and <em>O. dirphiaeem> De Santis, 1988, with a frequency of 0.45%, 1.08%, 1.97%, 17.86%, 43.65% and 34.99%, respectively.

    KEY-WORDS: Biological control; Paraná-pine.

  11. Efeito dos fungicidas Fosetil-Al e Metalaxil na colonização de mudas de <em>Citrus sinensisem> (L.) Osbeck enxertadas em <em>C. limonem> (L.) Burmf Effect of the fungicides Fosetyl-Al and Metalaxyl on arbuscular mycorrhizal colonization of seedlings of <em>Citrus sinensisem> (L.) Osbeck grafted onto <em>C. limonem> (L.) Burmf

    Luiz Antônio Graciolli; Vera Lúcia Ramos Bononin; Rosilaine Carrenho

    2000-01-01

    O efeito dos fungicidas Fosetil-Al e Metalaxil, recomendados para prevenção e controle da gomose, sobre o desenvolvimento de fungos micorrízicos arbusculares (FMA) em Citrus sinensis Osbeck enxertado em C. limon Burmf foi investigado. Três experimentos foram realizados em 1990 e 1992, em Casa Branca e Ilha Solteira, estado de São Paulo, Brasil, respectivamente. Coletas de raízes foram feitas após a aplicação dos fungicidas, em intervalos mensais e semanais em Casa Branca, e a cada três dias e...

  12. Uso de dexmedetomidina em anestesiologia

    Villela Nivaldo Ribeiro

    2003-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A dexmedetomidina é um novo agonista alfa2-adrenérgico que apresenta relação de seletividade entre os receptores alfa2:alfa1 de 1600:1, com importante ação sedativa e analgésica, bom controle hemodinâmico frente ao estresse e que pode produzir, por si só, anestesia. Este agente tem sido empregado para promover analgesia e sedação no período pós-operatório e nas unidades de tratamento intensivo. Devido à suas propriedades, recentemente, a dexmedetomidina passou a ser utilizada também na sala de operações, como fármaco coadjuvante em anestesia. Assim, este artigo faz uma revisão da literatura com relação ao uso da dexmedetomidina na prática anestésica. CONTEÚDO: São apresentados os principais trabalhos com o emprego da dexmedetomidina em Anestesiologia, seja como medicação pré-anestésica, ou durante o ato anestésico-cirúrgico. O mecanismo de ação dos fármacos alfa2-agonistas e as propriedades farmacocinéticas e farmacodinâmicas da dexmedetomidina também são revistos neste artigo. CONCLUSÕES: O uso da dexmedetomidina como medicação pré-anestésica, durante anestesia, ou no período pós-operatório, promove boa estabilidade hemodinâmica. Há redução do consumo de anestésicos durante a anestesia. Os pacientes sedados com a dexmedetomidina podem ser despertados, quando solicitados, e tornarem-se cooperativos. Mesmo doses elevadas do fármaco não provocam depressão respiratória. Bradicardia é um efeito adverso observado com freqüência, problema amenizado pela administração lenta da droga. Assim, a dexmedetomidina torna-se importante recurso adicional para a prática clínica da Anestesiologia, com possibilidade de uso em diversos tipos de pacientes e procedimentos cirúrgicos.

  13. HAICAIS EM MANOEL DE BARROS

    Profª Drª Nery Reiner

    2012-09-01

    Full Text Available O objetivo deste artigo, voltado para a criação poética de Manoel de Barros, é focalizar o conceito da obra de arte como jogo. Escolhemos Manoel de Barros, porque o lúdico, a brincadeira e o humor estão sempre presentes em sua obra. A escolha dos dados, o encaixe de palavras escolhidas a dedo, no eixo paradigmático, formam um caleidoscópio, mostrando novas estruturas, deixando explícito o desejo de brincar com os elementos linguísticos e da natureza. Para este trabalho, escolhemos, para análise, pequenos poemas semelhantes aos haicais japoneses e outros menores ainda, com dois ou até um verso apenas. Contaremos, nesta pesquisa, com a ajuda de teóricos como Johan Huizinga, Ezra Pound, Octavio Paz, Lévi-Strauss, Olga Savary e Alfredo Bosi.

  14. Project X RFQ EM Design

    Romanov, Gennady; /Fermilab; Hoff, Matthew; Li, Derun; Staples, John; Virostek, Steve; /LBNL

    2012-05-09

    Project X is a proposed multi-MW proton facility at Fermi National Accelerator Laboratory (FNAL). The Project X front-end would consist of an H- ion source, a low-energy beam transport (LEBT), a CW 162.5 MHz radio-frequency quadrupole (RFQ) accelerator, and a medium-energy beam transport (MEBT). Lawrence Berkeley National Laboratory (LBNL) and FNAL collaboration is currently developing the designs for various components in the Project X front end. This paper reports the detailed EM design of the CW 162.5 MHz RFQ that provides bunching of the 1-10 mA H- beam with acceleration from 30 keV to 2.1 MeV.

  15. Poderes locais em perspectiva comparada

    Fernando Ruivo

    2012-10-01

    Full Text Available “Os romances não começam como queremos, mas como eles querem”, afirmou Gabriel Garcia Marquez. Similarmente, as nossas vidas nunca decorrem como individualmente as tínhamos pensado, desejado e planeado. Ora, tal como as nossas vidas, também as reformas político-administrativas e as políticas públicas territorializadas não começam, deve dizer-se, como queremos, isto é, como pensámos, desejámos e planeámos, mas em boa parte como elas querem, como se tivessem, afinal, alguma vida própria, a qual...

  16. Osteoporose em caprinos Osteoporosis in goats

    Fábio B. Rosa; Glauco J.N. Galiza; Ricardo B. Lucena; Taiara M. Silva; Rafaela A. Caprioli; Claudio S.L. Barros; Rafael A. Fighera; Glaucia D Kommers

    2013-01-01

    Foi realizado um estudo de casos de osteoporose em caprinos provenientes de uma propriedade na área de abrangência do LPV-UFSM, determinando a epidemiologia, o quadro clínico-patológico e discutindo os prováveis mecanismos patogenéticos. Cinco cabras, fêmeas, SRD, de seis meses a seis anos de idade foram afetadas. As cabras eram mantidas em campo nativo, sem suplementação com ração e sob superlotação. Os principais sinais clínicos foram emagrecimento, dificuldade de locomoção e permanência em...

  17. O Trabalho Plurativo em Presidente Prudente

    Sandro Mauro Guirro

    2011-11-01

    Full Text Available Atualmente, vêm ocorrendo mudanças no campo brasileiro, principalmente nas  propriedades localizadas próximas a malha urbana da cidade. Esse processo se verifica com mais intensidade em cidades como Campinas, Sorocaba, Jundiaí entre outras cidades próximas aos grandes centros urbanos. Em Presidente Prudente, esse processo dá sinais de existência em resposta à crise pela qual vem passando, sobretudo a pequena agricultura. Está-se diante da intensificação das mudanças de funções do trabalho inserido na lavra agrária.

  18. Determinantes do endividamento municipal em Portugal

    Ferreira, Fernando Diogo Vilaça

    2011-01-01

    Dissertação de mestrado em Economia, Mercados e Políticas Públicas O objectivo desta dissertação consiste em analisar os factores que explicam o índice de endividamento dos Municípios portugueses entre 2003 e 2007. Em Portugal, os municípios surgiram no pós-25 de Abril de 1974 com atribuições desempenhadas até aí pela Administração Central. No entanto, nem sempre foram acompanhadas por transferências suficientes provocando o recurso ao crédito. Este endividamento municipal t...

  19. Sistemas de Indicadores de Desempenho em Projetos

    Julia Garaldi Borges; Marly Monteiro de Carvalho

    2011-01-01

    O presente trabalho visa propor um sistema de indicadores de desempenho de projetos, a partir da análise da importância dos critérios de sucesso em projetos. A abordagem metodológica foi a de pesquisa-ação desenvolvida em uma empresa de engenharia, com atuação em diversos setores. Foram utilizadas várias fontes de evidência, tais como análise do atual sistema de indicadores da empresa, análise dos projetos nas bases de dados e entrevistas com representantes do escritório de projetos e com ger...

  20. Tricolemoma em coelho Tricholemmoma in a rabbit

    Krishna Duro de Oliveira; Ticiana do Nascimento França; Alexander Pérez González; Paulo Vargas Peixoto

    1999-01-01

    Tricolemoma é um raro tumor benigno, composto por células epiteliais claras derivadas da bainha externa da raiz do folículo piloso. Esses tumores têm sido descritos no homem e raramente em cães. No presente relato, descreve-se a ocorrência de um tricolemoma, de 1cm de diâmetro em um coelho adulto, cujas características histológicas são muito semelhantes às descritas para esses tumores em cães.Tricholemmoma is a rare benign tumor composed of clear epithelial cells derived from the outer root s...

  1. Comorbidades psiquiátricas em dependentes químicos em abstinência em ambiente protegido Psychiatric comorbidities in abstinent drug addict in a protected environment

    Adriana Raquel Binsfeld Hess; Rosa Maria Martins de Almeida; André Luiz Moraes

    2012-01-01

    O objetivo desta pesquisa foi verificar a frequência de comorbidades psiquiátricas, utilizando Mini International Neuropsychiatric Interview, em diferentes grupos de dependentes químicos em abstinência, em ambiente protegido, classificados de acordo com o tipo de droga utilizada: (1) grupo controle (n = 37); (2) dependentes em abstinência de álcool (n = 8); (3) dependentes em abstinência de álcool, maconha e crack/cocaína (n = 24); e (4) dependentes em abstinência de múltiplas substâncias psi...

  2. 3-(1<em>H>-Indol-3-yl-4-(morpholin-4-ylcyclobut-3-ene-1,2-dione

    Johann Grünefeld

    2012-06-01

    Full Text Available 3-(1<em>H>-Indol-3-yl-4-(morpholin-4-ylcyclobut-3-ene-1,2-dione was obtained in good yields (72–82% by nucleophilic substitution of 3-chloro-4-(1<em>H>-indol-3-ylcyclobut-3-ene-1,2-dione with morpholine.

  3. Three dimensional geometric morphometric study of the Ethiopian <em>Myomys - Stenocephalemysem> complex (Murinae, Rodentia

    Carlo Fadda

    2000-06-01

    Full Text Available Abstract Geometric morphometrics was used to investigate the Ethiopian <em>Myomys - Stenocephalemysem> complex, and to suggest possible explanations for differences in size and shape. The four species of the complex (<em>M. albipesem>, <em>M. ruppiem>, <em>S. griseicaudaem>, <em>S. albocaudataem> and a Kenyan species, <em>M. fumatusem>, were studied using Procrustes analysis of three dimensional landmarks collected over the skull. All these species occur in very different habitats, from forests at 1000 m up to the Afro Alpine moorlands above 4000 m. There is a substantial contradiction between phylogenetic relationships based on chromosomal rearrangements and allozymes (two distinct lineages corresponding to the two genera, and mtDNA (<em>Stenocephalemys> being paraphyletic. Geometric morphometrics supports the former hypothesis. Partial Least-Squares analysis shows a significant relation between variation in size and shape and altitude, which strongly suggests that adaptation is a major causal factor for divergence in the morphology of the skull. Size increases with altitude, paralleling a clinal change in shape, which involves stenocephaly as characterising the highland species. This shape modification allows the rodents to scan the sky efficiently for birds, which represent the main category of predators in the Afro Alpine moorlands.

  4. Identification of Volatile Components of Liverwort (<em>Porella cordaeanaem> Extracts Using GC/MS-SPME and Their Antimicrobial Activity

    Maria Elisabetta Guerzoni

    2012-06-01

    Full Text Available Chemical constituents of liverwort (<em>Porella cordaeanaem> extracts have been identified using solid-phase microextraction-gas chromatography mass spectrometry (SPME-GC/MS. The methanol, ethanol and ethyl acetate extracts were rich in terpenoids such as sesquiterpene hydrocarbons (53.12%, 51.68%, 23.16%, and monoterpene hydrocarbons (22.83%, 18.90%, 23.36%, respectively. The dominant compounds in the extracts were β-phellandrene (15.54%, 13.66%, 12.10% and β-caryophyllene (10.72%, 8.29%, 7.79%, respectively. The antimicrobial activity of the extracts was evaluated against eleven food microorganisms using the microdilution and disc diffusion methods. The minimum inhibitory concentration (MIC varied from 0.50 to 2.00 mg/mL for yeast strains (<em>Saccharomyces cerevisiae 635em>, <em>Zygosacharomyces bailii 45em>, <em>Aerobasidium pullulans L6Fem>, <em>Pichia membranaefaciens OC 71em>, <em>Pichia membranaefaciens OC 70em>, <em>Pichia anomalaem> <em>CBS 5759em>, <em>Pichia anomala DBVPG 3003em> and<em> em>>Yarrowia lipolytica RO13em>, and from 1.00 to 3.00 mg/mL for bacterial strains<em> em>(Salmonella> <em>enteritidis 155em>, <em>Escherichia coli 555em> and <em>Listeria monocytogenes 56Lyem>. Methanol extract showed better activity in comparison with ethanol and ethyl acetate extracts. High percentages of monoterpene and sesquiterpene hydrocarbons could be responsible for the better antimicrobial activity.

  5. Evaluación de la susceptibilidad a la corrosión por picado del acero API 5L x42 expuesto a un ambiente con cloruros y CO2 mediante la técnica de ruido electroquímico

    Rodríguez-Vanegas, N.

    2011-10-01

    Full Text Available The concentration of chloride ions and the partial pressure of CO2 play an important role in the degradation of low-carbon steels used for the construction of pipelines in oil and gas industry. In order to evaluate the susceptibility of carbon steel API 5L X42 to pitting corrosion electrochemical noise and linear polarization resistance measurements were carried out in aqueous solutions containing chloride ions and CO2. The concentration of chloride ions was varied between, 10000 and 18000 ppm, and the CO2 partial pressure between 10 psi and 18 psi. Experimental results pointed out that the formation of protective layer, consisting mainly of FeCO 3, depends on the partial pressure of CO2 in the system. Nevertheless, the stability of this layer was considerably affected by increasing the concentration of chloride ions causing that localized corrosion has taken place in some areas of the surface of API 5L X42, which were detected by electrochemical noise echnique.La concentración de iones cloruro y la presión parcial de CO2, tienen un papel importante en el proceso de degradación de los aceros de bajo carbono empleados en la construcción de líneas de transporte en industrias petroleras. Con el fin de evaluar la susceptibilidad del acero al carbono API 5L X42 a la corrosión por picado, se realizaron medidas de ruido electroquímico y resistencia a la polarización lineal en soluciones acuosas de iones cloruro con concentraciones entre 10.000 y 18.000 ppm, variando la presión parcial de CO2 entre 10 psi y 18 psi. Los resultados indican que la formación de una capa protectora, constituida principalmente por FeCO3, depende de la presión parcial de CO2 del sistema. No obstante, la estabilidad de dicha capa es afectada significativamente por el aumento de la concentración de iones cloruro, que producen fenómenos de corrosión localizada en algunas áreas de la superficie del acero API 5L X42, los cuales fueron detectados por la técnica de

  6. Feeding habits of the genet <em>Genetta genettaem> in an Iberian continental wetland

    Maite Sánchez

    2009-02-01

    Full Text Available Abstract This study quantified the diet of the genet <em>Genetta genettaem> in an Iberian continental wetland, the Galachos Nature Reserve, northern Spain, based on the frequency with which items appeared in five monthly-surveyed latrines during 2004-2005. Prey types were identified <em>de visuem> using identification keys and expert advice. the genet was confirmed as an opportunistic and generalist predator, its diet including mammals (95.0%, plants (68.3% and arthropods (60.0% as main prey. With the exception of a newly available prey species, the alien crayfish <em>Procambarus clarkiiem>, the genet probably consumed arthropods because of chance encounters rather than active search. The consumption of fruits and small mammals varied seasonally. Riassunto Alimentazione della genetta <em>Genetta genettaem> in un'area umida continentale della penisola iberica La dieta della genetta è stata investigata in un'area umida interna della Spagna settentrionale, la riserva Naturale dei Galachos. La frequenza di ciascuna categoria alimentare è stata espressa come numero di occorrenze mansili in cinque latrine monitorate per il periodo 2004-2005. Le categorie sono state identificate <em>de visuem> tramite chiavi per il riconoscimento o l'intervento di singoli esperti. I risultati confermano il comportamento alimentare generalista e opportunista della genetta. La dieta ha incluso principalmente mammiferi (95%, vegetali (68.3% e artropodi (60%. Questi ultimi, con l'eccezione del gambero <em>Procambarus clarkiiem>, introdotto e di recente presenza, sono probabilmente utilizzati in modo opportunistico, piuttosto che in seguito a ricerca attiva. L'uso dei frutti e dei micromammiferi varia stagionalmente.

  7. Chemical Composition and Biological Activities of the Essential Oils from <em>Duguetia lanceolataem> St. Hil. Barks

    Kaplan, Maria A. C.; Rodarte, Mírian P.; Maria P. H. Amaral; Araújo, Aílson A. L.; Míriam A. O. Pinto; Maria S. Alves; Glauciemar Del-Vechio-Vieira; Orlando V. Sousa

    2012-01-01

    Essential oils of <em>Duguetia lanceolataem> barks, obtained at 2 (T2) and 4 h (T4), were identified by gas chromatography and gas chromatography/mass spectrometry. β-Elemene (12.7 and 14.9%), caryophyllene oxide (12.4 and 10.7%) and β-selinene (8.4 and 10.4%) were the most abundant components in T2 and T4, respectively. The essential oils inhibited the growth of <em>Staphylococcus aureusem>,> Streptococcus pyogenesem>, <em>Escherichia coli&l...

  8. Influência do ambiente em cultivares de feijoeiro-comum em cerrado com baixa altitude

    Helton Santos Pereira; Válter Martins de Almeida; Leonardo Cunha Melo; Adriane Wendland; Luís Cláudio de Faria; Maria José Del Peloso; Mariana Cruzick de Souza Magaldi

    2012-01-01

    O objetivo desse trabalho foi identificar genótipos de feijoeiro-comum com alta adaptabilidade e estabilidade de produção e verificar a ocorrência de interação genótipos x ambientes (GxA) para diferentes caracteres em algumas regiões de cerrado com baixa altitude no Estado do Mato Grosso. Foram realizados 12 ensaios em blocos casualizados, com três repetições, em épocas de semeadura da seca e do inverno, no Estado do Mato Grosso, em 2008 e 2009. Os ensaios foram compostos por 19 genótipos com...

  9. Characterization of the Antibacterial Activity and the Chemical Components of the Volatile Oil of the Leaves of <em>Rubus parvifoliusem> L.

    Yongqing Cai

    2012-06-01

    Full Text Available <em>Rubus parvifoliusem> L. (Rp is a medicinal herb that possesses antibacterial activity. In this study, we extracted the volatile oil from the leaves of Rp to assess its antibacterial activity and analyze its chemical composition. A uniform distribution design was used to optimize the extraction procedure, which yielded 0.36% (<em>w/w> of light yellowish oil from the water extract of Rp leaves. We found that the extracted oil effectively inhibited the growth of a wide range of Gram positive and negative bacteria, including <em>Staphylococcus aureusem>, <em>Staphylococcus epidermidisem>, <em>Enterococcus faecalisem>, <em>Escherichia coliem>, <em>Pseudomonas aeruginosaem>, <em>Acinetobacter baumaniiem>, <em>Bacillus cloacaeem>, and <em>Klebsiella pneumoniaeem>. We further analyzed the components contained in the hydro-distillated Rp volatile oil by gas chromatography-mass spectroscopy. Twenty nine compounds were identified, including 4-hydroxy-3-methoxystyrene (66%, 3,7,11,15-tetramethyl-2-hexadecen-1-ol (10% and 4-<em>tert>-butylbenzoic acid (2%. Our results suggest that one or multiple constituents contained in Rp volatile oil may account for its antibacterial activity.

  10. EMS in Taiwan: past, present, and future.

    Chiang, Wen-Chu; Ko, Patrick Chow-In; Wang, Hui-Chih; Yang, Chi-Wei; Shih, Fuh-Yuan; Hsiung, Kuang-Hua; Ma, Matthew Huei-Ming

    2009-01-01

    Taiwan is a small island country located in East Asia. From around 1995 modern concepts of the EMS were imported and supported by legislation. Considerable progress has since been made towards the construction of an effective pre-hospital care system. This article introduces the current status of the EMS in Taiwan, including the systems, response configurations, funding, personnel, medical directorship, and outcome research. The features and problems of in-hospital emergency care are also discussed. Key areas for further development in the country vary depending on regional differences in available resource and population density. An analysis of the strength, weakness, opportunity, and threats of the evolving EMS in Taiwan could be an example for other countries where the EMS is undergoing a similar process of development and optimisation. PMID:19059690

  11. Platelet-Activating Factor (PAF Antagonistic Activity of a New Biflavonoid from <em>Garcinia nervosaem> var. <em>pubescens> King

    Azura Abdul Ghani

    2012-09-01

    Full Text Available The methanol extract of the leaves of <em>Garcinia nervosaem> var. <em>pubescens> King, which showed strong inhibitory effects on platelet-activating factor (PAF receptor binding, was subjected to bioassay-guided isolation to obtain a new biflavonoid, II-3,I-5, II-5,II-7,I-4',II-4'-hexahydroxy-(I-3,II-8-flavonylflavanonol together with two known flavonoids, 6-methyl-4'-methoxyflavone and acacetin. The structures of the compounds were elucidated by spectroscopic methods. The compounds were evaluated for their ability to inhibit PAF receptor binding to rabbit platelets using 3H-PAF as a ligand. The biflavonoid and acacetin showed strong inhibition with IC50 values of 28.0 and 20.4 µM, respectively. The results suggest that these compounds could be responsible for the strong PAF antagonistic activity of the plant.

  12. Probióticos em avicultura

    Gil de los Santos João Rodrigo

    2005-01-01

    Full Text Available Durante os últimos anos, o incremento de toxinfecções alimentares em humanos pela ingestão de produtos avícolas contaminados com bactérias, sugeriu que produtos oriundos de aves portadoras dessas bactérias podem veiculá-las ao consumidor, provocando doenças entéricas em humanos. Essas observações e a restrição, por parte do mercado consumidor, ao uso de antimicrobianos na produção animal, aumentaram o interesse mundial pelos probióticos e, conseqüentemente, o número de pesquisas realizadas. Esta revisão mostra os avanços e a situação em que se encontram os probióticos em relação à indústria avícola.

  13. Biocerâmicas em Endodontia

    Oliveira, Pedro Miguel da Silva

    2014-01-01

    Introdução e Objectivos: Biocerâmicas incluem materiais cerâmicos projetados especificamente para uso em Medicina e Medicina Dentária. O objetivo deste trabalho é efetuar uma revisão bibliográfica em que demonstre a avaliação das propriedades físico-químicas das biocerâmicas e o seu uso em Endodontia. Radiopacidade, Fluidez, pH e Libertação de íões cálcio foram analisados e comparados com outros materiais usados em Endodontia. Material e Métodos: Para a realização da pesq...

  14. <em>Helicobacter pyloriem> Disrupts Host Cell Membranes, Initiating a Repair Response and Cell Proliferation

    Hsueh-Fen Juan

    2012-08-01

    Full Text Available <em>Helicobacter pyloriem> (<em>H. pyloriem>, the human stomach pathogen, lives on the inner surface of the stomach and causes chronic gastritis, peptic ulcer, and gastric cancer. Plasma membrane repair response is a matter of life and death for human cells against physical and biological damage. We here test the hypothesis that <em>H. pyloriem> also causes plasma membrane disruption injury, and that not only a membrane repair response but also a cell proliferation response are thereby activated. Vacuolating cytotoxin A (VacA and cytotoxin-associated gene A (CagA have been considered to be major <em>H. pyloriem> virulence factors. Gastric cancer cells were infected with <em>H. pyloriem> wild type (vacA+/cagA+, single mutant (ΔvacA or ΔcagA or double mutant (ΔvacA/ΔcagA strains and plasma membrane disruption events and consequent activation of membrane repair components monitored. <em>H. pyloriem> disrupts the host cell plasma membrane, allowing localized dye and extracellular Ca2+ influx. Ca2+-triggered members of the annexin family, A1 and A4, translocate, in response to injury, to the plasma membrane, and cell surface expression of an exocytotic maker of repair, LAMP-2, increases. Additional forms of plasma membrane disruption, unrelated to <em>H.> pylori em>exposure, also promote host cell proliferation. We propose that <em>H. pyloriem> activation of a plasma membrane repair is pro-proliferative. This study might therefore provide new insight into potential mechanisms of <em>H. pyloriem>-induced gastric carcinogenesis.

  15. <em>Hedyotis diffusaem> Willd Inhibits Colorectal Cancer Growth <em>in Vivoem> via Inhibition of STAT3 Signaling Pathway

    Jun Peng; Wei Xu; Aling Shen; Zhenfeng Hong; Jianwei Zeng; Youzhi Zhan; Ling Zhang; Lili Wang; Lihui Wei; Jiumao Lin; Qiaoyan Cai

    2012-01-01

    Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers; therefore it is a major focus in the development of novel anti-cancer agents. <em>Hedyotis diffusaem> Willd has been used as a major component in several Chinese medicine formulas for the clinical treatment of colorectal cancer (CRC). However, the precise mechanism of its anti-tumor activity remains largely unclear. Using a CRC mous...

  16. Local feeding specialization of the red fox (<em>Vulpes vulpesem>) in response to eastern cottontail (<em>Sylvilagus floridanusem>) introduction (NW Italy)

    Alessandro Balestrieri; Luigi Remonti; Claudio Prigioni

    2006-01-01

    Abstract To appreciate the influence of the introduction of the Eastern cottontail (<em>Sylvilagus floridanusem>) on the food habits of the red fox (Vulpes vulpes), between June 1998 and February 2000 fox diet was investigated by means of scat analysis (N=115) in a 250 ha wide Natural Reserve of NW Italy, and compared with data collected in the same area prior to cottontail colonization (1988-1989). Comparison included also the diet of badgers (...

  17. Net Energy, CO2 Emission and Land-Based Cost-Benefit Analyses of <em>Jatropha> em>Biodiesel: A Case Study of the Panzhihua Region of Sichuan Province in China

    Xiangzheng Deng

    2012-06-01

    Full Text Available Bioenergy is currently regarded as a renewable energy source with a high growth potential. Forest-based biodiesel, with the significant advantage of not competing with grain production on cultivated land, has been considered as a promising substitute for diesel fuel by many countries, including China. Consequently, extracting biodiesel from <em>Jatropha> curcasem> has become a growing industry. However, many key issues related to the development of this industry are still not fully resolved and the prospects for this industry are complicated. The aim of this paper is to evaluate the net energy, CO2 emission, and cost efficiency of <em>Jatropha> biodiesel as a substitute fuel in China to help resolve some of the key issues by studying data from this region of China that is well suited to growing <em>Jatropha>. Our results show that: (1 <em>Jatropha> biodiesel is preferable for global warming mitigation over diesel fuel in terms of the carbon sink during <em>Jatropha> tree growth. (2 The net energy yield of <em>Jatropha> biodiesel is much lower than that of fossil fuel, induced by the high energy consumption during <em>Jatropha> plantation establishment and the conversion from seed oil to diesel fuel step. Therefore, the energy efficiencies of the production of <em>Jatropha> and its conversion to biodiesel need to be improved. (3 Due to current low profit and high risk in the study area, farmers have little incentive to continue or increase <em>Jatropha> production. (4 It is necessary to provide more subsidies and preferential policies for <em>Jatropha> plantations if this industry is to grow. It is also necessary for local government to set realistic objectives and make rational plans to choose proper sites for <em>Jatropha> biodiesel development and the work reported here should assist that effort. Future research focused on breading high-yield varieties, development of efficient field

  18. A Favela posta em Cena

    Fabiana Valdoski Ribeiro

    2010-08-01

    Full Text Available Em uma realidade de urbanização calcada no aprofundamento dos processos de expropriação e espoliações se consolida o fenômeno da produção de uma morfologia intitulada Favela, que continua a representar um desafio teórico e prático para pesquisadores. Este desafio é enfrentado de várias formas sendo uma delas desenhada no âmbito de duas publicações do Observatório das Favelas (Rio de Janeiro assentadas na busca conceitual do termo favela e objetivando a efetivação de políticas públicas. Esta meta remonta a trajetória deste Observatório que criado em 2001 pensa a inserção da Favela no âmbito das políticas de Estado. A primeira publicação intitulada “Favela: alegria e dor na cidade” (2005 se compõem de quatro capítulos que expõem um movimento da história de formação das favelas na cidade do Rio de Janeiro, as formas de intervenção do Estado, a prática cotidiana dos moradores como manifestação das transgressões diante as opressões e finaliza com as propostas de caminhos possíveis de superação das desigualdades e ampliação da democracia. O argumento central dos autores se direciona para o questionamento das visões de homogeneidade, ausência, carência e apartamento das favelas diante da cidade apontando a urgência de construção de um projeto de cidade democrático e fraterno.Ao longo do texto os autores vão descrevendo os exemplos destas visões e analisa o resultado delas por meio de como a população residente vive, pois são ora invisíveis, ora criminalizados, ora caracterizados enquanto um problema social estabelecendo, portanto, uma lógica autoritária que legitimará no decorrer da história das favelas, as intervenções estatais. Este movimento molda uma linha argumentativa que tenta explicitar o negativo diante a produção possível para o “morar’, que calcado na impossibilidade do acesso à terra pelo imperativo da propriedade privada empurra grandes contingentes populacionais

  19. EMS Stations, EMS: Represents the locations of EMS Stations in Washington County., Published in 2009, 1:1200 (1in=100ft) scale, Washington County GIS Office.

    NSGIC GIS Inventory (aka Ramona) — This EMS Stations dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Orthoimagery information as of 2009. It is described as 'EMS:...

  20. Development of 101 Gene-based Single Nucleotide Polymorphism Markers in Sea Cucumber, <em>Apostichopus japonicusem>>

    Wei Lu

    2012-06-01

    Full Text Available Single nucleotide polymorphisms (SNPs are currently the marker of choice in a variety of genetic studies. Using the high resolution melting (HRM genotyping approach, 101 gene-based SNP markers were developed for <em>Apostichopus japonicusem>, a sea cucumber species with economic significance for the aquaculture industry in East Asian countries. HRM analysis revealed that all the loci showed polymorphisms when evaluated using 40 <em>A. japonicusem> individuals collected from a natural population. The minor allele frequency ranged from 0.035 to 0.489. The observed and expected heterozygosities ranged from 0.050 to 0.833 and 0.073 to 0.907, respectively. Thirteen loci were found to depart significantly from Hardy–Weinberg equilibrium (HWE after Bonferroni corrections. Significant linkage disequilibrium (LD was detected in one pair of markers. These SNP markers are expected to be useful for future quantitative trait loci (QTL analysis, and to facilitate marker-assisted selection (MAS in <em>A. japonicusem>.

  1. LESÕES FOLIARES EM MUDAS DE PEQUIZEIRO (Caryocar brasiliensis Cambess) LEAF LESIONS OF YOUNG PLANTS OF PEQUIZEIRO

    Yvo de Carvalho; Leila Garcez de Araújo

    2007-01-01

    Foram descritas as características de lesões e morfologia de colônias de <em>Pestalotia> <em>sp>., <em>Phomopsis spem>., <em>Stigmella spem>., <em>Chaetophoma sp.em>, <em>Helminthosporium sp.em> e <em>Epicoccum sp. em>obtidas de folhas de mudas de pequizeiro em viveiros nos municípios de Goiânia e Hidrolândia (GO). ...

  2. A MORTE EM CINCO ATOS

    André Lira

    2015-01-01

    Full Text Available ResumoOs avanços técnicos atuais põem adiante muitasexpectativas relativas à nossa mortalidade.Devedores de uma longa tradição de dicotomias,como corpo e alma, cultura e naturezae muitas outras, nós estamos realmente observandoa virtualização crescente da realidade.Por que isso está ocorrendo e a que isso estáconduzindo? Nós iremos propor uma dançaapaixonada com a questão da morte, não parasuperá-la ou repeli-la, como normalmente éexperienciada no mundo moderno. Em vezdisso, nessa mesma dança, tentaremos redescobrirnossas raízes terrenas, articulando odivino e a singularidade de nossas vidas comodevidos ao horizonte que a morte revela.Morte como horizonte, isto é, a própria possibilidadede ser, quer dizer que a mortalidadeé o próprio dom da felicidade, o permanentee essencial sentido da história. E o horizontedas possibilidades que a morte oferece a cadaum dos seres humanos aparece como um silênciosagrado, sempre um espelho escuro requisitandoe questionando nossas identidadese certezas, nos pondo em movimento. Nessesentido, recuperar o sentido existencial damorte é pedir abrigo, mais uma vez, no ventremisterioso da terra.Palavras-chave: Morte; corpo; terra.AbstractTh e current technical advancements putforward many expectations concerning ourmortality. In debt of a long tradition of dichotomies,such as body and soul, cultureand nature and many others, we are indeedwatching the increasing virtualization of reality.Why is that happening and what is it leadingto? We will propose a passionate dancewith the question of death, not to overcomeor repel it, as it normally is experienced in themodern world. Instead, in that very dance,we will try to rediscover our earthly roots, articulatingthe divinity and singularity of ourlives as due to the horizon that death unveils.Death as horizon, that is, the possibility ofbeing itself, means that mortality is the truegift of happiness, the everlasting and essentialmeaning of history

  3. Commensal <em>Pseudomonas> Species Isolated from Wastewater and Freshwater Milieus in the Eastern Cape Province, South Africa, as Reservoir of Antibiotic Resistant Determinants

    Anthony I. Okoh

    2012-07-01

    Full Text Available <em>Pseudomonas> species are opportunistic pathogens with implications in a wide range of diseases including cystic fibrosis and sickle cell anaemia. Because of their status as multidrug resistant (MDR and extremely drug resistant (XDR bacteria <em>Pseudomonas> species represent a threat to public health. Prevalence, antibiogram and associated antibiotic resistant genes of <em>Pseudomonas> species isolated from freshwater and mixed liquor environments in the Eastern Cape Province of South Africa were assessed. Polymerase chain reaction (PCR based technique was used to identify the isolates and screen for antibiotic resistant genes. The result shows occurrence of <em>Pseudomonas> spp. in freshwater and mixed liquor as follows: 71.42% and 37.5% (<em>P. putidaem>, 14.28% and 31.25% (<em>P. flourescensem>, 7.14% and 6.25% (<em>P. aeruginosaem> and 7.14% and 25% for other <em>Pseudomonas> species respectively. Disk diffusion antibiogram of the <em>Pseudomonas> isolates from the two locations showed 100% resistance to penicillin, oxacillin, clindamycin, rifampicin and 100% susceptibility to ciprofloxacin and gentamicin with varied percentage resistances to cephalothin, nalidixic acid, tetracycline, and ampicillin. The <em>blaTEM> antibiotic resistant gene was detected in 12.5% of <em>P. putidaem>, 57.14% of <em>P. fluorescensem>, 100% <em>P. aeruginosaem> and 40% in other <em>Pseudomonas> species. Similarly, Integrons conserved segment were detected in 12.5% of <em>P. putidaem>, 57.14% of <em>P. fluorescensem>, 100% of <em>P. aeruginosaem> and 40% of other <em>Pseudomonas> species. The presence of <em>blaTEM> gene and integrons conserved segment in some of the isolates is worrisome and suggest <em>Pseudomona>s species as important reservoirs of multidrug resistance genes in the Eastern Cape Province environment.

  4. Preussianone, a New Flavanone-Chromone Biflavonoid from <em>Garcinia preussiiem> Engl.

    Gerhard Bringmann; Kurt Hostettmann; Jean-Luc Wolfender; Alain Meli Lannang; Nkengfack, Augustin E; Barbara Hertlein-Amslinger; Karine Ndjoko-Ioset; Bernadette Biloa Messi

    2012-01-01

    A new flavanone-chromone biflavonoid, preussianone (1), has been isolated from the leaves of <em>Garcinia preussiiem>, along with four known biflavonoids. The absolute stereostructures were elucidated by chemical, spectroscopic, and chiroptical methods. The biological properties of the new biflavonoid against several bacterial strains were evaluated.

  5. <em>In Vitro em>Phytotoxicity and Antioxidant Activity of Selected Flavonoids

    Rita Patrizia Aquino

    2012-05-01

    Full Text Available The knowledge of flavonoids involved in plant-plant interactions and their mechanisms of action are poor and, moreover, the structural characteristics required for these biological activities are scarcely known. The objective of this work was to study the possible <em>in vitro em>phytotoxic effects of 27 flavonoids on the germination and early radical growth of <em>Raphanus sativus em>L.> and <em>Lepidium sativumem> L., with the aim to evaluate the possible structure/activity relationship. Moreover, the antioxidant activity of the same compounds was also evaluated. Generally, in response to various tested flavonoids, germination was only slightly affected, whereas significant differences were observed in the activity of the various tested flavonoids against radical elongation. DPPH test confirms the antioxidant activity of luteolin, quercetin, catechol, morin, and catechin. The biological activity recorded is discussed in relation to the structure of compounds and their capability to interact with cell structures and physiology. No correlation was found between phytotoxic and antioxidant activities.

  6. Enzymatic Properties and Mutational Studies of Chalcone Synthase from <em>Physcomitrella patensem>

    Mahiran Basri

    2012-08-01

    Full Text Available <em>Pp>CHS is a member of the type III polyketide synthase family and catalyses the synthesis of the flavonoid precursor naringenin chalcone from <em>p>-coumaroyl-CoA. Recent research reports the production of pyrone derivatives using either hexanoyl-CoA or butyryl-CoA as starter molecule. The Cys-His-Asn catalytic triad found in other plant chalcone synthase predicted polypeptides is conserved in <em>Pp>CHS. Site directed mutagenesis involving these amino acids residing in the active-site cavity revealed that the cavity volume of the active-site plays a significant role in the selection of starter molecules as well as product formation. Substitutions of Cys 170 with Arg and Ser amino acids decreased the ability of the <em>Pp>CHS to utilize hexanoyl-CoA as a starter molecule, which directly effected the production of pyrone derivatives (products. These substitutions are believed to have a restricted number of elongations of the growing polypeptide chain due to the smaller cavity volume of the mutant’s active site.

  7. Antibacterial Secondary Metabolites from the Cave Sponge <em>Xestospongia em>sp.

    Sridevi Ankisetty

    2012-05-01

    Full Text Available Chemical investigation of the cave sponge <em>Xestospongia em>sp. resulted in the isolation of three new polyacetylenic long chain compounds along with two known metabolites. The structures of the new metabolites were established by NMR and MS analyses. The antibacterial activity of the new metabolites was also evaluated.

  8. Actinomicose da Mama em Gestante

    Mottola Jr Juvenal

    2001-01-01

    Full Text Available A actinomicose mamária é doença inflamatória rara, com poucos casos descritos na literatura. Pode ser primária da mama quando resultante de traumas na pele e papila mamária, e, secundária, quando de origem toracopleural. Sua apresentação clínica é variável, devendo ser diferenciada das doenças mais comuns, dentre elas as mastites e também as neoplasias, como o carcinoma inflamatório. Seu diagnóstico é realizado pela cultura da secreção, com a identificação das colônias de Actinomyces sp. Seu tratamento é a drenagem, quando indicada, a antibioticoterapia endovenosa e manutenção oral por tempo prolongado. Os autores relatam caso de abscesso retromamário por Actinomyces sp. em gestante de 12 semanas que apresentava tumoração mamária expansiva na mama esquerda.

  9. Dermatite multifatorial em um canino

    C.B. Matos

    2012-12-01

    Full Text Available Relatou-se um caso clínico de dermatite multifatorial em cão, envolvendo Demodex canis, Sporothrix schenckii e bactérias dos gêneros Staphylococcus e Streptococcus. O animal, macho, da raça Pit Bull, com um ano e três meses de idade, apresentou lesões úmidas, hiperêmicas, descamativas e ulcerativas nas regiões do pescoço e do tórax. Exames laboratoriais confirmaram o diagnóstico de infecção concomitante por fungo, bactéria e parasito. A terapia antimicrobiana com moxidectina, itraconazol e amoxicilina foi efetiva, com remissão dos sinais clínicos após 30 dias de tratamento. Este relato salienta a importância do diagnóstico de certeza, que foi determinante para estabelecimento da terapêutica adequada e recuperação do animal.

  10. Monorquidismo em um equino marchador

    Jéssica Fontana de Magalhães

    2015-06-01

    Full Text Available O monorquidismo é um quadro raramente descrito em equinos, que não apresenta descrições prévias na literatura nacional. Trata-se de um equino adulto brasileiro, com oito anos de idade, sem raça definida, porém com características de raças de origem nacional. Por abordagem inguinal do lado esquerdo, localizou-se a túnica vaginal intacta, que, aberta, continha a cauda de um epidídimo mal formado, o ducto deferente e um delgado pedículo vascular, mas sem indícios de testículo. Exames histológicos e hormonais confirmaram a ausência de tecido testicular. Conclui-se que os exames histológicos e hormonais são essenciais para o diagnóstico de monorquidismo que, apesar de raro, também pode acometer equinos nacionais

  11. Self: um conceito em desenvolvimento

    Lídia Suzana Rocha de Macedo

    2012-08-01

    Full Text Available Diversas definições de self coexistem nas teorias e práticas psicológicas. Essa variedade é resultante de bases epistemológicas a partir das quais se adotam estratégias diferentes para abordar e demarcar os limites do objeto em questão e descrevê-lo. Este estudo teve como objetivo oferecer uma revisão dos conceitos de self e uma reflexão sobre como esse conceito se articula nas diferentes abordagens teóricas da psicologia. Destaca-se que dilemas centrais à psicologia do desenvolvimento atravessam o conceito de self. Por essa razão, apresenta-se a tese de que, ao analisar cada definição de self, deve-se buscar responder como cada teoria colocou-se diante das dicotomias estabilidade versus transformação, específico versus universal e mundo interno versus mundo externo.

  12. Local feeding specialization of the red fox (<em>Vulpes vulpesem> in response to eastern cottontail (<em>Sylvilagus floridanusem> introduction (NW Italy

    Alessandro Balestrieri

    2006-03-01

    Full Text Available Abstract To appreciate the influence of the introduction of the Eastern cottontail (<em>Sylvilagus floridanusem> on the food habits of the red fox (Vulpes vulpes, between June 1998 and February 2000 fox diet was investigated by means of scat analysis (N=115 in a 250 ha wide Natural Reserve of NW Italy, and compared with data collected in the same area prior to cottontail colonization (1988-1989. Comparison included also the diet of badgers (<em>Meles melesem>, considered as potential competitors for food resources. Alien lagomorphs (mean percent volume, Vm% = 68% represented by far the most exploited resource, only three other food items reaching values of mean percent volume barely higher than 5%. Cottontails frequency of occurrence did not vary according either to season or to their reproductive cycle (II-IX vs. X-I, whilst diet niche breadth varied inversely proportional to the use of this key-resource. Overall fox trophic niche breadth varied from 0.64 in 1988-89 to 0.31 in 1998-00 (B, Levin’s index. These findings led us to consider the feeding habits of the fox in the study area as a result of local specialization of a typical generalist carnivore, according to the predictions of optimal foraging theory. No variation occurred in the badger niche breadth since cottontail introduction, whilst niche overlap between foxes and badgers decreased from 0.59 to 0.13 (O, Pianka’s index, possibly reducing competition for food in summer. Riassunto Specializzazione alimentare a livello locale della Volpe <em>Vulpes vulpesem> in risposta all’introduzione del Silvilago <em>Sylvilagus floridanusem> (Italia nord occidentale. Per valutare gli effetti dell’introduzione del Silvilago (<em>Sylvilagus floridanusem> sul comportamento alimentare della volpe (<em>Vulpes vulpesem>, nel periodo giugno 1998-febbraio 2000, la dieta del carnivoro è stata definita tramite l’analisi di 115

  13. Infracommunities of intestinal helminths of the Red Fox <em>Vulpes vulpesem> (Linnaeus, 1758 from Italian Alps

    Anna Rita Di Cerbo

    2003-10-01

    Full Text Available <em>Vulpes vulpesem> (Linnaeus, 1758 is one of the most common carnivore in Italy and its spread includes almost the whole national territory. The species shows an high ecological plasticity and a variable diet composition connected in part to human sources. This high adaptability permits the red foxes to colonize different habitats like the suburbs of large cities as well as the small villages located in mountain areas. On the other hand, the tourism pressure seems to assume a great importance in the Alps, also in those areas where the foxes live. So, indirect interactions could take place between these animals and the humans. The role of <em>V. vulpesem> in the zoonoses has not to be understated since this carnivore could transmit parasitic diseases that are able to cause serious pathologies in humans. This study aims just to investigate on intestinal communities of helmiths of <em>V. vulpesem> in order to make progress in current knowledge on epidemiological situation in Italian Alps. During 1998-2003, we have examined 450 foxes from Trentino Alto Adige, Veneto, Lombardia and Valle d'Aosta. The specimens collected were found dead or have been hunted (according to national law n. 157/92 in localities situated between 170 and 2200 m a.s.l. The carcasses were carried to the provincial sections of Zooprofilattici Institutes, where the intestine was drawn by each sample and all the material was sent to the Faculty of Veterinary Medicine of Milan. Parasitological examination of the small intestines was performed by the analysis of the whole sediment and counting technique (SCT. Parasites were preserved in alcohol 70° before to be clarified or stained and identified by microscope (Zeiss Axioscop. Mean abundance, mean intensity and prevalence were calculated for each taxon of helminth. Dates of sampling were grouped within the four seasons. Statistic tests were performed with software package SPSS rel. 11.5 and spatial analysis with the

  14. Teor de nitrato em alface cultivada em sistemas hidropônico e convencional

    Beninni Elisabete R. Yonamini

    2002-01-01

    Full Text Available O monitoramento do teor de nitrato nos alimentos é importante, uma vez que poderão ser formados compostos prejudiciais à saúde humana e animal após sua ingestão. Com o objetivo de avaliar o teor de nitrato presente em alface, foram coletadas e analisadas as folhas de alface crespa comercializada no Município de Londrina, cultivada em sistemas hidropônico e convencional. Os valores encontrados variaram entre 26 e 2.568 mg.kg-1 de peso fresco, sendo que as plantas cultivadas em sistema hidropônico apresentaram teores superiores em relação às cultivadas em sistema convencional, porém abaixo do limite máximo de nitrato permitido para alface, na Europa.

  15. Farmacocinética do propofol em nanoemulsão em cães

    Rafael Messias Luiz; Martielo Ivan Gehrcke; Marcos Paulo Antunes de Lima; Anicleto Poli; Aury Nunes de Moraes; Felipe Hertzing Farias; Nilson Oleskovicz

    2013-01-01

    O propofol em nanoemulsão é uma nova formulação constituída por sistemas nanoemulsionados, caracterizado pela ausência do veículo lipídico. A modificação do veículo pode acarretar alterações farmacocinéticas, resultando em diferentes taxas de distribuição e excreção do propofol. O objetivo deste estudo foi avaliar a farmacocinética de uma nova formulação de propofol em nanoemulsão do tipo óleo em água, comparando com a formulação tradicional em emulsão lipídica. Foram utilizadas seis cadelas ...

  16. Synthesis and Cytotoxicity Evaluation of 13-<em>n>-Alkyl Berberine and Palmatine Analogues as Anticancer Agents

    Lei Zhang

    2012-09-01

    Full Text Available By introducing long carbon-chain alkyl groups at the C-13 position of berberine and palmatine, 13-<em>n>-hexyl/13-<em>n>-octyl berberine and palmatine chloride analogues 4ad were synthesized and examined by MTT assays for cytotoxic activity in seven human cancer cell lines (7701QGY, SMMC7721, HepG2, CEM, CEM/VCR, KIII, Lewis, yielding IC50 values of 0.02 ± 0.01–13.58 ± 2.84 μM. 13-<em>n>-Octyl palmatine (compound 4d gave the most potent inhibitor activity, with an IC50 of 0.02 ± 0.01 μM for SMMC7721. In all cases, the 13-<em>n>-alkyl berberine and palmatine analogues 4ad were more cytotoxic than berberine and palmatine. In addition, compounds 4ad also exhibited more potent cytotoxicity than berberine and palmatine in mice with S180 sarcoma xenografted<em> in vivoem>. The primary screening results indicated that the 13-<em>n>-hexyl/13-<em>n>-octyl berberine and palmatine analogues might be valuable source for new potent anticancer drug candidates.

  17. Carbono orgânico e elementar em partículas em suspensão em habitações

    Pinho, Isabel Cristina Correia de

    2011-01-01

    As concentrações de partículas em suspensão na atmosfera (PM10) e o seu conteúdo em carbono foram determinadas em amostras recolhidas em quatro locais distintos do concelho de Aveiro. Na recolha das amostras foram utilizados dois amostradores, de baixo caudal um para o ar interior e outro para o ar exterior, em simultâneo, com tempos de amostragem de 48 horas. As concentrações de PM10 foram determinadas por gravimetria, enquanto que o material carbonoso foi determinado ...

  18. Estudo parasitológico em caes da raça rottweiler em canis na regiao metropolitana de Curitiba

    Dalledone, Fernando Quadros

    2012-01-01

    O objetivo do presente trabalho foi o de verificar as primeiras reinfecções por helmintos detectadas através de exames coproparasitológicos em cães da raça rottweiler, em canis de empresas de segurança. Os animais dispostos em casais, com massa corpórea variável entre 47Kg e 62 Kg, todos com quatro anos de idade, localizaram-se em vinte e cinco endereços diferentes, distribuídos em cinco zonas, e divididos em cinco grupos, com cinco casais cada, na cidade de Curitiba, Paraná. Os animais receb...

  19. EM International, July 1994, Volume 2

    The Office of Environmental Management (EM) at the Department of Energy (DOE) is seeking out and leveraging foreign technology, data, and resources in keeping with EM's mandate to protect public health and the environment through the safe and cost-effective remediation of the Department's nuclear weapons sites. EM works closely with foreign governments, industry, and universities to obtain innovative environmental technologies, scientific and engineering expertise, and operations experience that will support EM's objectives. Where appropriate, these international resources are used to manage the more urgent risks at our sites, secure a safe workplace, help build consensus on critical issues, and strengthen our technology development program. Through international agreements EM engages in cooperative exchange of information, technology, and individuals. Currently, we are managing agreements with a dozen countries in Europe, Latin America, and Asia. These agreements focus on environmental restoration, waste management, transportation of radioactive wastes, and decontamination and decommissioning. This publication contains the following articles: in situ remediation integrated program; in-situ characterization and inspection of tanks; multimedia environmental pollutant assessment system (MEPAS); LLNL wet oxidation -- AEA technology. Besides these articles, this publication covers: EU activities with Russia; technology transfer activities; and international organization activities

  20. Roost selection by barbastelle bats (<em>Barbastella barbastellusem>, Chiroptera: Vespertilionidae in beech woodlands of central Italy

    Danilo Russo

    2003-10-01

    Full Text Available The barbastelle bat, <em>Barbastella barbastellusem> (Schreber, 1774 is a medium-sized, tree-dwelling vespertilionid classified as ?Endangered? in Italy; in western Europe it may be one of the rarest bat species. <em>B. barbastellusem> shows roosting preferences that should be regarded as a key point in conservation protocols. We examined roost selection in a breeding population of <em>B. barbastellusem> from the Abruzzo Lazio and Molise National Park (central Italy at three levels: woodland structure and management type; tree characteristics; and cavity characteristics. In 2001-2002, we fitted 31 adult <em>B. barbastellusem> (29 lactating females, one pregnant female and one male with 0.48g radio-tags and tracked them to their roost-trees. The bats were tracked for 4.5 ± 3.7 days (range: 0-12 days. We located 33 roosts used by 25 subjects (1.8±1.2 roosts/bat, range 1-5. The bats switched roosts frequently: 13 bats used more than one tree over the study period. A chi-square analysis showed that the roosts were not distributed at random across woodland categories: unmanaged woodland was positively selected, whereas shelterwood-harvested woodland was used in proportion to its availability, and ?pastures+scattered trees? was avoided. Twenty out of 33 roost trees were dead <em>Fagus sylvaticaem> trees; conversely, living <em>F. sylvaticaem> dominated in a tree sample obtained at random; dead trees were used more than expected (Χ² test, <em>P> <0.001. Overall, roost trees were significantly taller and had a larger diameter at breast?s height and more cavities than random trees; they also had a lower percent canopy closure than random trees. To highlight which variables were actually associated with selection, we devised a logistic regression model. The full model was significant (<em>P> <0.001; removal of tree type and tree height affected the model significantly, but the other variables did not produce detectable effects. The

  1. The EM technology development strategy

    The Office of Technology Development (TD) supports research and development of technologies that will lower cost, reduce risk, improve safety, and accelerate cleanup of the Nuclear Weapons Complex and provide solutions to currently untractable environmental problems. The TD strategic plan outlines Applied Research, Development, Demonstration, Testing, and Evaluation (RDDT and E) that will provide needed technology products to be used by Environmental Restoration and Waste Management operations (i.e., our customers). The TD strategic plan is derived from EM Goals, Objectives, and Strategy and is incorporated into DOE'S Five-Year Plan for Environmental Restoration and Waste Management. The TD strategic plan is developed based on integrating customer requirements, and is complemented by a top-down, bottom-up analysis of Site Specific Technology Needs and environmental problems. The execution of TD's strategic plan is implemented largely through Integrated Programs (IP) and Integrated Demonstrations (ID). IDs have proven to be a cost-effective method of managing technology development, testing and evaluation, and implementation of successful technology systems into the DOE Environmental Restoration and Waste Management Programs. The Savannah River ID for Volatile Organic Compounds (VOCs) in Saturated Soils resulted in a 51 percent cost savings over stand-alone demonstrations, saving over $8 million. The IPs and IDs are selected based on customer needs, technical complexity, and complex-wide regulatory and compliance agreements. New technology systems are selected for incorporation into an IP or ID from offerings of the DOE laboratories, industry, and the universities. A major TD initiative was announced in August 1991, with the release of a Program Research and Development Announcement (PRDA) requesting industry and universities to propose innovative new technologies to clean up the Weapons Complex. (author)

  2. EMS adaptation for climate change

    Pan, C.; Chang, Y.; Wen, J.; Tsai, M.

    2010-12-01

    The purpose of this study was to find an appropriate scenario of pre-hospital transportation of an emergency medical service (EMS) system for burdensome casualties resulting from extreme climate events. A case of natural catastrophic events in Taiwan, 88 wind-caused disasters, was reviewed and analyzed. A sequential-conveyance method was designed to shorten the casualty transportation time and to promote the efficiency of ambulance services. A proposed mobile emergency medical center was first constructed in a safe area, but nearby the disaster area. The Center consists of professional medical personnel who process the triage of incoming patients and take care of casualties with minor injuries. Ambulances in the Center were ready to sequentially convey the casualties with severer conditions to an assigned hospital that is distant from the disaster area for further treatment. The study suggests that if we could construct a spacious and well-equipped mobile emergency medical center, only a small portion of casualties would need to be transferred to distant hospitals. This would reduce the over-crowding problem in hospital ERs. First-line ambulances only reciprocated between the mobile emergency medical center and the disaster area, saving time and shortening the working distances. Second-line ambulances were highly regulated between the mobile emergency medical center and requested hospitals. The ambulance service of the sequential-conveyance method was found to be more efficient than the conventional method and was concluded to be more profitable and reasonable on paper in adapting to climate change. Therefore, additional practical work should be launched to collect more precise quantitative data.

  3. Valor nutritivo de macrófitas aquáticas flutuantes (<em>Eichhornia crassipesem>, <em>Pistia stratiotesem> e <em>Salvinia molestaem>) utilizadas no tratamento de efluentes de aqüicultura Nutritive value of free-floating aquatic macrophytes (<em>Eichhornia crassipesem>, <em>Pistia stratiotesem> and <em>Salvinia molestaem>), used in aquaculture waste treatment

    Antonio Fernando Monteiro Camargo; Gustavo Gonzaga Henry-Silva

    2002-01-01

    O objetivo deste estudo foi avaliar o valor nutritivo das macrófitas aquáticas flutuantes, Eichhornia crassipes (Mart.) Solms (Pontederiaceae), Pistia stratiotes (L.) (Araceae) e Salvinia molesta (Mitchell) (Salviniaceae), utilizadas em um sistema de tratamento de efluentes de tilápia do Nilo (Oreochromis niloticus), e inferir sobre o potencial de aproveitamento da biomassa dessas espécies. As amostras de biomassa vegetal foram obtidas através de um quadrado de 0,25m2 de área e separadas em p...

  4. <em>Scutellaria baicalensisem> Alleviates Cantharidin-Induced Rat Hemorrhagic Cystitis through Inhibition of Cyclooxygenase-2 Overexpression

    Li-Chun Lin

    2012-05-01

    Full Text Available Cantharidin, an active component in mylabris, is used in traditional Chinese medicine (TCM to treat scabies and hepatoma, but accompanied by hemorrhagic cystitis. Evidence shows that cantharidin induces human bladder carcinoma cell death through COX-2 overexpression<em> in vitroem>. In TCM, <em>Scutellaria baicalensisem> is usually used to cure mylabris-induced hematuria. This work was undertaken to determine the mechanisms of cantharidin-induced rat hemorrhagic cystitis and explore the uroprotective effect of <em>S. baicalensis.em> <em>In vitroem> results showed cantharidin could induce cytotoxicity through prostaglandin (PGE2 overproduction of T24 cells. Boiling-water extract of <em>S. baicalensis em>(SB-WE could significantly inhibit PGE2 production and COX-2 expression in lipo-polysaccharide-induced RAW 264.7 cells, indicating obvious anti-inflammatory abilities. <em>In vivoem> results indicated that cantharidin caused rat hemorrhagic cystitis with hematuria via c-Fos and COX-2 overexpression. SB-WE was given orally to cantharidin-treated rats, whereby hematuria level, elevated PGE2 and COX-2 protein overexpression were significantly and dose-dependently inhibited by SB-WE. The anti-inflammatory components of SB-WE are baicalin and wogonin, whose contents were 200.95 ± 2.00 and 31.93 ± 0.26 μg/mg, respectively. In conclusion, cantharidin induces rat cystitis through c-Fos and COX-2 over-expression and <em>S. baicalensisem> can prevent the resulting hematuria because of its anti-inflammatory effects.

  5. The diet of the fox (<em>Vulpes vulpesem> in woodlands of Orobie Alps (Lombardy region, Northern Italy / Alimentazione della Volpe (<em>Vulpes vulpesem> in aree boscate delle Alpi Orobie

    Marco Cantini

    1991-07-01

    Full Text Available Abstract The diet of the fox was investigated by analysis of 273 scats, collected along standard trails from April to November 1987 and 1988. Food habits of foxes were described for three altitudinal ranges. Mammals, mainly <em>Clethrionomys glareolusem> and <em>Microtus multiplexem>, were the staple food (percentage of frequency 42.8%, followed by fruits and other vegetables (26.7% and 37.3% respectively. Birds, Invertebrates (mainly Insects and garbage were little eaten. The game species (ungulates, hares, pheasants occurred with a low frequency (8.4% in the diet. The trophic niche breadth varied little through the altitudinal ranges and the seasons. The trophic niche overlap between the fox and the genus <em>Martes> (190 scats of <em>M. martesem> and <em>M. foinaem> were examined is relatively wide (O=0.868. Riassunto La dieta della Volpe (<em>Vulpes vulpesem> in aree boscate delle Alpi Orobie (Val Lesina è stata indagata nel periodo aprile-novembre 1987 e 1988 mediante l'analisi di 273 feci, raccolte lungo percorsi-campione ricadenti in tre piani vegetazionali. I Mammiferi, in particolare <em>Clethrionomys glareolusem> e <em>Microtus multiplexem>, sono la componente principale della dieta (frequenza percentuale 42,8%. Rilevante è anche il consumo di frutti (soprattutto in estate e autunno e di altri vegetali (26,7% e 37,3% rispettivamente, mentre poco frequente è quello di Uccelli, Invertebrati e rifiuti. Complessivamente ridotta è l'azione predatoria della Volpe nei confronti delle specie di interesse venatorio (Ungulati, lepri, Galliformi. L'ampiezza della nicchia trofica mostra modeste variazioni stagionali e altitudinali. I1 grado di sovrapposizione tra la nicchia trofica della Volpe e quella del genere <em>Martes>, quest'ultima ricavata dall'analisi di 190 feci di Martora (<em>M. martesem> e Faina (<em>M. foinaem>, è elevato (O=0,868. Tuttavia, poiché in condizioni di

  6. Tricolemoma em coelho Tricholemmoma in a rabbit

    Krishna Duro de Oliveira

    1999-06-01

    Full Text Available Tricolemoma é um raro tumor benigno, composto por células epiteliais claras derivadas da bainha externa da raiz do folículo piloso. Esses tumores têm sido descritos no homem e raramente em cães. No presente relato, descreve-se a ocorrência de um tricolemoma, de 1cm de diâmetro em um coelho adulto, cujas características histológicas são muito semelhantes às descritas para esses tumores em cães.Tricholemmoma is a rare benign tumor composed of clear epithelial cells derived from the outer root sheath of the hair follicle. The tumor has been described in man and rarely in dogs. This report deals with the occurrence of a tricholemmoma , with a diemeter of 1cm, in an adult rabbit. The histologic features are similar to those described in such tumors in dogs.

  7. SISTEMAS ERP EM AMBIENTE MÓVEL

    GRAVE, ANA CRISTINA DA CONCEIÇÃO

    2002-01-01

    Esta dissertação procura soluções para a ampliação de sistemas ERP para além da sua natureza cliente-servidor tradicional, dotando-os com a capacidade de processamento em ambiente móvel com operação desconectada. Apresenta dois modelos, um para a geração automática de aplicações para execução de transacções em ERPs em operação desconectada, e outro que caracteriza as aplicações geradas e a interacção com estas. Os modelos foram validados através da construção de um protótipo de um gerad...

  8. The Fox (<em>Vulpes vulpesem> L.) as a principal reservoir of trichinellosis in Italy / La Volpe (<em>Vulpes vulpesem> L.) principale serbatoio della trichinellosi in Italia

    Edoardo Pozio

    1991-01-01

    Abstract The fox (<em>Vulpes vulpesem> L.) is the principal reservoir of trichinellosis in Italy. The prevalence of infection varies from 1% to over 25% in some localities of central-southern Italy. The vulpine infection is not present in Sicily and Sardinia. A biochemical analysis was employed to identify the aetiological agent as <em>Trichinella> T3, a taxon distributed in the Palearctic region. Infected fox ...

  9. The DOE/EM facility transition program

    The mission of EM-60 is to plan, implement, and manage receipt of surplus facilities resulting from downsizing of the DOE Weapons Complex facilities and DOE operating program offices to EM, and to ensure prompt deactivation of such facilities in order to reach a minimum surveillance and maintenance condition. The revised organizational structure of EM-60 into four offices (one at headquarters, and the other three at field sites), reflects increased operating functions associated with deactivation, surveillance, and maintenance of facilities. EM-60's deactivation and transition role concerns technical, socioeconomic, institutional, and administrative issues. The primary objective of the deactivation process is to put facilities in the lowest surveillance and maintenance condition safely and quickly by driving down the open-quotes mortgageclose quotes costs of maintaining them until final disposition. EM-60's three key activities are: (1) Inventory of surplus facilities - The 1993 Surplus Facility Inventory and Assessment (SFIA) serves as a planning tool to help the Department and EM-60 determine optimal transition phasing, with safety and cost-effectiveness remaining a priority. (2) Management of accelerated facility life cycle transition - Transitions currently underway illustrate site issues. These include addressing the interests of federal and state regulatory agencies as well as interests of local stakeholders, safe management of large amounts of production residues, and options for treatment, storage, transportation, and disposal. Of equal importance in the transition process is planning the optimal transition of the labor force. (3) Economic development - to address the socio-economic impacts on affected communities of the severe and rapid downsizing of the DOE Weapons Complex, DOE is pursuing an approach that uses the land, equipment, technology assets, and highly skilled local workforces as a basis for alternative economic development

  10. Isojacareubin from the Chinese Herb <em>Hypericum japonicumem>: Potent Antibacterial and Synergistic Effects on Clinical Methicillin-Resistant <em>Staphylococcus aureusem> (MRSA

    Gen-Chun Wang

    2012-07-01

    Full Text Available Through bioassay-guided fractionation of the extracts from the aerial parts of the Chinese herb <em>Hypericum japonicumem> Thunb. Murray, Isojacareubin (ISJ was characterized as a potent antibacterial compound against the clinical methicillin-resistant S<em>taphylococcus aureusem> (MRSA. The broth microdilution assay was used to determine the minimal inhibitory concentrations (MICs and minimal bactericidal concentrations (MBCs of ISJ alone. The results showed that its MICs/MBCs ranged from 4/16 to 16/64 μg/mL, with the concentrations required to inhibit or kill 50% of the strains (MIC50/MBC50 at 8/16 μg/mL. Synergistic evaluations of this compound with four conventional antibacterial agents representing different types were performed by the chequerboard and time-kill tests. The chequerboard method showed significant synergy effects when ISJ was combined with Ceftazidime (CAZ, Levofloxacin (LEV and Ampicillin (AMP, with the values of 50% of the fractional inhibitory concentration indices (FICI50 at 0.25, 0.37 and 0.37, respectively. Combined bactericidal activities were also observed in the time-kill dynamic assay. The results showed the ability of ISJ to reduce MRSA viable counts by log10CFU/mL at 24 h of incubation at a concentration of 1 × MIC were 1.5 (LEV, additivity, 0.92 (CAZ, indifference and 0.82 (AMP, indifference, respectively. These <em>in vitroem> anti-MRSA activities of ISJ alone and its synergy with conventional antibacterial agents demonstrated that ISJ enhanced their efficacy, which is of potential use for single and combinatory therapy of patients infected with MRSA.

  11. A pesquisa em epidemiologia no Brasil

    Reinaldo Guimarães

    2001-08-01

    Full Text Available Descreve-se a pesquisa em epidemiologia no Brasil na atualidade. Utiliza várias fontes secundárias de dados, com ênfase na versão 4.0 do Diretório dos Grupos de Pesquisa no Brasil (2000 do CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico. O critério para o reconhecimento de grupo integrante da massa crítica em epidemiologia foi o desenvolvimento, pelo menos, de uma linha de pesquisa nessa subárea, conforme definido pelo líder do grupo. Foi identificado o universo da pesquisa epidemiológica, que se constituiu de 176 grupos e 320 linhas de pesquisa. Foram apresentadas e discutidas as relações entre o financiamento para a pesquisa, tendo como foco os programas de pós-graduação incluídos no sistema Capes (Coordenação de Aperfeiçoamento de Pessoal do Ensino Superior, e as pesquisas em saúde, em saúde coletiva e epidemiologia, a capacidade instalada de pesquisa em epidemiologia, sua distribuição geográfica e institucional, os pesquisadores e os estudantes que participam diretamente das linhas de pesquisa, os temas de pesquisa, os padrões de divulgação de resultados das pesquisas e os periódicos em que são publicados os artigos completos.

  12. Profilaxia para úlcera de estresse em pacientes internados em UTI pediátrica

    Taisa E. Araujo; Sandra M.G. Vieira; Paulo R.A. Carvalho

    2010-01-01

    OBJETIVO: Avaliar a utilização de profilaxia para úlcera de estresse (UE), em pacientes internados, de cinco unidades de terapia intensiva pediátrica (UTIP) de Porto Alegre (RS). MÉTODOS: Estudo multicêntrico, prospectivo, transversal, observacional. Foram avaliados os prontuários dos pacientes internados em dia definido para visitação, entre abril de 2006 e fevereiro de 2007, excluindo os avaliados em visitas anteriores e aqueles com hemorragia digestiva alta na admissão. Foram avaliados a i...

  13. Dizer o singular em meio plural: jogos e forjas de escrita em oficinas virtuais

    Souza, Pedro

    2001-01-01

    Este trabalho é parte de uma pesquisa maior em que estou analisando discursivamente práticas coletivas de escrita observáveis em propostas de oficinas de textos em determinados espaços da internet. Aqui me ocupo particularmente de uma experiência francesa de produção de textos que descrevem cenas ocorridas na cidade de Paris. Detenho-me precisamente na proposta de um site na internet que convida os internautas a participar da produção de uma coletânea de descrições curtas, estruturadas segund...

  14. Letalidade e internacoes de pacientes em hemodialise em plano de saude

    Sergio Adriano Loureiro Bersan; Carlos Faria Santos Amaral; Isabel Cristina Gomes; Mariangela Leal Cherchiglia

    2013-01-01

    OBJETIVO: Analisar desfechos clínicos de pacientes incidentes em hemodiálise vinculados a operadora de plano de saúde. MÉTODOS: Estudo de coorte de incidentes em hemodiálise em Belo Horizonte, MG, de 2004 a 2008, a partir de registros no banco de dados de operadora de planos de saúde. Variáveis independentes: sexo, idade, tempo entre primeira consulta com nefrologista e início da hemodiálise, tipo do primeiro acesso vascular, diabetes mellitus, tempo de permanência hospitalar/ano de trat...

  15. Variabilità microsatellitare in popolazioni italiane di martora, <em>Martes martesem>

    Licia Colli

    2003-10-01

    Full Text Available La martora, <em>Martes martesem>, è un mustelide storicamente presente su gran parte del territorio italiano, soprattutto dove siano presenti foreste mature altamente strutturate e ricche di risorse. Nel corso dei decenni passati, cause quali la deforestazione con conseguente frammentazione dell'habitat, la caccia e la persecuzione da parte dell'uomo hanno portato ad un sensibile declino sia nel numero d'individui sia di popolazioni in tutta l'Europa. Frammentazione degli areali e diminuzione del numero di soggetti costituiscono le cause principali di un limitato flusso genico con conseguente formazione di popolazioni isolate di martora e perdita di variabilità genetica (Kyle <em>et al.em>, 2003. Per queste ragioni la martora risulta attualmente tutelata secondo quanto previsto dalla Convenzione di Berna (appendice III e dalla Direttiva europea 92/43/CEE "Habitats & Species". Di fronte a prospettive di tipo conservazionistico, diventa necessario disporre di metodologie per la valutazione della variabilità residua nella specie a livello d'individui e di popolazioni. Secondo numerosi Autori, i microsatelliti costituiscono marcatori molto efficaci nella descrizione della struttura genetica e della storia demografica di specie (Beaumont & Bruford, 1999; Linares, 1999. Il presente lavoro propone i risultati ottenuti attraverso il confronto di due campioni costituiti da individui di <em>Martes martesem> provenienti dalla Sardegna (25 esemplari e dal territorio italiano (6 esemplari. L'analisi è stata condotta a livello di 7 loci microsatellitari dinucleotidici polimorfici. Il valore di FST calcolato dal confronto dei due gruppi è risultato pari a 0,102 e ricade nel <em>range> di variazione identificato di recente in popolazioni nord-europee di martora (Kyle <em>et al.em>, 2003. L'analisi della varianza molecolare (AMOVA, condotta a due livelli gerarchici, ha permesso in particolare di ripartire la varianza del campione

  16. Marcas de luxo em Portugal: o sucesso em contexto de crise económica

    Pereira, Filipa Marques Serra

    2011-01-01

    Mestrado em Marketing “O «Luxury Goods Worldwide Market Study» estima que as vendas globais aumentem 10% este ano, para 191 mil milhões de euros” in Diário Económico 2011/10/23. Portugal não é excepção. Surgem constantemente manchetes de jornais acerca do crescimento de mercado de luxo em contexto de crise. As razões que levam os consumidores a escolherem produtos de luxo são muitas e de diversas dimensões: financeira, funcional, individual e social. Além disso, o luxo hoje em dia pode ...

  17. A Novel Cyclodextrin Glycosyltransferase from Alkaliphilic <em>Amphibacillus> sp. NPST-10: Purification and Properties

    Garabed Antranikian

    2012-08-01

    Full Text Available Screening for cyclodextrin glycosyltransferase (CGTase-producing alkaliphilic bacteria from samples collected from hyper saline soda lakes (Wadi Natrun Valley, Egypt, resulted in isolation of potent CGTase producing alkaliphilic bacterium, termed NPST-10. 16S rDNA sequence analysis identified the isolate as <em>Amphibacillus> em>sp. CGTase was purified to homogeneity up to 22.1 fold by starch adsorption and anion exchange chromatography with a yield of 44.7%. The purified enzyme was a monomeric protein with an estimated molecular weight of 92 kDa using SDS-PAGE. Catalytic activities of the enzyme were found to be 88.8 U mg−1 protein, 20.0 U mg−1 protein and 11.0 U mg−1 protein for cyclization, coupling and hydrolytic activities, respectively. The enzyme was stable over a wide pH range from pH 5.0 to 11.0, with a maximal activity at pH 8.0. CGTase exhibited activity over a wide temperature range from 45 °C to 70 °C, with maximal activity at 50 °C and was stable at 30 °C to 55 °C for at least 1 h. Thermal stability of the purified enzyme could be significantly improved in the presence of CaCl2. <em>K>m and <em>V>max values were estimated using soluble starch as a substrate to be 1.7 ± 0.15 mg/mL and 100 ± 2.0 μmol/min, respectively. CGTase was significantly inhibited in the presence of Co2+, Zn2+, Cu2+, Hg2+, Ba2+, Cd2+, and 2-mercaptoethanol. To the best of our knowledge, this is the first report of CGTase production by <em>Amphibacillus> sp. The achieved high conversion of insoluble raw corn starch into cyclodextrins (67.2% with production of mainly β-CD (86.4%, makes <em>Amphibacillus> sp. NPST-10 desirable for the cyclodextrin production industry.

  18. Descoberta de conhecimentos em base de dados

    Ramos, Célia M. Q.; Lobo, Fernando

    2003-01-01

    A sociedade actual é caracterizada por uma inundação de dados provenientes de diversas fontes, existentes numa vasta gama de áreas económicas, sociais, cientificas, etc. A análise dos dados, armazenados em Bases de Dados, é cada vez mais pertinente para garantir a competitividade e o sucesso das organizações. Este artigo apresenta a nova área de conhecimento “Descoberta de Conhecimento em Bases de Dados” que permite efectuar análises dos dados e extrair conhecimento útil e adequado para o ...

  19. Arenas de conflito em torno do cuidado

    Guita Grin Deber

    2014-06-01

    Full Text Available O texto explora as arenas de conflito em torno do cuidado em asilos. Equipe técnica, cuidadoras e idosos dependentes constituem uma configuração específica da vida nessas instituições. Trata-se de analisar o modo pelo qual a questão é abordada por Pascal Molinier no artigo "Interseccionalidade, cuidado e feminismo", tendo como contraponto minha pesquisa sobre mulheres imigrantes cuidadoras de idosos na Itália e o emprego doméstico no Brasil.

  20. Estados depressivos em diabetes tipo 2

    Góis, Carlos José Fernandes da Conceição, 1957-

    2013-01-01

    A diabetes tipo 2 e a depressão são duas patologias com incidência crescente. A comorbilidade diabetes tipo 2 e depressão tem sido amplamente investigada, nomeadamente num óptica de influência recíproca e de impacto da depressão sobre a evolução da diabetes. O presente trabalho sobre estados depressivos em diabetes tipo 2 respondeu a perguntas em áreas carenciadas de estudos, nomeadamente na população portuguesa, ou contribuiu com perspetivas inovadoras com interesse clínico. Os principais ob...

  1. Competência em cuidados paliativos

    Rijo, Sara Filipa de Leão Bacelar

    2012-01-01

    Os Cuidados Paliativos são cuidados totais e activos, prestados por profissionais com formação específica e treino adequado, exigindo preparação técnica, formação teórica e experiência prática efectiva. A formação diferenciada em Cuidados Paliativos é essencial e imprescindível para a organização e qualidade dos mesmos. No contexto do Mestrado em Cuidados Paliativos da Universidade Católica Portuguesa, vertente profissionalizante, foi realizado um estágio de 300 horas presen...

  2. Ensinar e aprender em ambientes virtuais tridimensionais

    Gonçalves, Vitor

    2012-01-01

    Os mundos virtuais constituem ambientes simulados, normalmente tridimensionais, mediados através de tecnologias de informação e comunicação e que se destinam a ser frequentados por utilizadores que interagem com outros através de avatares. Estes ambientes virtuais tridimensionais (3D) podem ser desenvolvidos recorrendo a software de desenho 3D em versões comerciais e open source ou criados em servidores de mundos virtuais tridimensionais já existentes, tais como o Second Life ou similares. No...

  3. PERCEPÇÃO EM GROUPWARE EDUCACIONAIS

    Socorro Vânia Lourenço Alves

    2009-07-01

    Full Text Available Este artigo apresenta os principais conceitos sobre percepção (awareness e mecanismos de percepção em groupware educacionais. Também discute a importância do suporte à percepção nestes sistemas, identifica os tipos de percepção necessários em uma situação de aprendizagem colaborativa e, por fim, apresenta uma classificação para mecanismos responsáveis de fornecer percepção aos usuários finais destes sistemas.

  4. NATURE AND LAW IN THE <em>INSTITUTAS> OF GAIO NATUREZA E DIREITO NAS <em>INSTITUTAS> DE GAIO

    Alfredo Carlos Storck

    2011-09-01

    Full Text Available

    In a very famous passage of his <em>Institutes>, the ancient jurist Gaius had divided the Roman Private Law in two parts: the Civil Law and the Law of People. The former is the Law created by the Roman people, whereas the latter is the Law followed by every nation.

    Despite its classical origin, there is some disagreement among specialists about the right way to interpret this distinction. By the beginning of the 20th century, historians like Michel Villey had seen in this distinction the influence of Greek philosophy (Stoic but even Aristotelian among the Roman jurists. But Levy and more recently Kelly have challenged this view and proposed that, in the roman period, philosophers and jurists had completely distinct notions of nature and natural law. The aim of this paper is not to prove the exact influence of Greek philosophy among jurists, but only to suggest that it is not possible to give an interpretation of the classical texts without ascribing to them a theoretical notion of the natural law.

    Em uma famosa passagem de suas <em>Institutas>, o jurista romano Gaio dividiu o direito privado em duas partes: o direito civil e o direito dos povos. O primeiro é o direito criado pelo povo romano enquanto o segundo é o direito seguido por todas as nações. A despeito de sua origem clássica, os especialistas discordam acerca do modo de interpretar essa tese. No início do século XX, historiadores como Michel Villey viram na distinção sinais da influência da filosofia grega (estóica e mesmo aristotélica entre os juristas romanos. Posteriormente Levy e mais recentemente Kelly contestaram essa afirmação e defenderam que filósofos e juristas possuíam, no período clássico, noções de natureza e direito natural completamente distintas. O objetivo desse artigo não está em provar a exata influência da filosofia grega entre os juristas, mas apenas em sugerir que não é possível fornecer uma interpretação dos

  5. Rapsódia em agosto

    Sergio Leitão

    2015-01-01

    Neste artigo analiso se a tragédia das explosões nucleares em Hiroshima e Nagasaki ensinou algo de definitivo à humanidade, demonstrando o poder fatal das armas nucleares, o que continuaria a justificar o seu banimento da face da Terra. E o faço debatendo em que medida as discussões sobre o poder atômico repercutiram no Brasil, apontando as similaridades entre os argumentos utilizados nos idos dos anos 1970 e no momento atual, quando setores do país argumentam que não podemos prescindir do po...

  6. Risk Communication Within the EM Program

    Edelson, M.

    2003-02-26

    The U.S. Department of Energy Environmental Management program (EM) conducts the most extensive environmental remediation effort in the world. The annual EM budgets have exceeded $6,000,000,000 for approximately ten years and EM has assumed responsibility for the cleanup of the largest DOE reservations (i.e., at Hanford, Washington, Aiken, South Carolina, and Idaho Falls, Idaho) as well as the facilities at Rocky Flats, Colorado and in Ohio. Each of these sites has areas of extensive radioactive and chemical contamination, numerous surplus facilities that require decontamination and removal, while some have special nuclear material that requires secure storage. The EM program has been criticized for being ineffective (1) and has been repeatedly reorganized to address perceived shortcomings. The most recent reorganization was announced in 2001 to become effective at the beginning of the 2003 Federal Fiscal Year (i.e., October 2002). It was preceded by a ''top to bottom'' review (TTBR) of the program (2) that identified several deficiencies that were to be corrected as a result of the reorganization. One prominent outcome of the TTBR was the identification of ''risk reduction'' as an organizing principle to prioritize the activities of the new EM program. The new program also sought to accelerate progress by identifying a set of critical activities at each site that could be accelerated and result in more rapid site closure, with attendant risk, cost, and schedule benefits. This paper investigates how the new emphasis on risk reduction in the EM program has been communicated to EM stakeholders and regulators. It focuses on the Rocky Flats Environmental Technology Site (RFETS) as a case study and finds that there is little evidence for a new emphasis on risk reduction in EM communications with RFETS stakeholders. Discussions between DOE and RFETS stakeholders often refer to ''risk,'' but the word serves as a

  7. o caso da Semana Santa em Braga

    Santos, José Fernando Oliveira

    2011-01-01

    Dissertação apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Empresariais. A realização de eventos tem vindo a ser considerada uma das mais importantes manifestações do Turismo em Portugal e no Mundo, sendo notório que os mesmos geram uma dinâmica na economia das localidades. Assim, importa saber que tipos de impactos resultam desses eventos. A Semana Santa da Cidade de Braga é um dos maiores eventos de recriação r...

  8. Seguimento farmacoterapêutico em idosos polimedicados

    Abrantes, Mário Filipe Barbeitos

    2013-01-01

    Este estudo surge devido ao grande interesse que o investigador possui acerca da área do seguimento farmacoterapêutico e da polimedicação. A população idosa mundial tem vindo a aumentar drasticamente devido, em grande parte, às melhorias das condições de vida e dos avanços na medicina, nomeadamente ao nível dos tratamentos farmacológicos. Hoje em dia e para manter um determinado estado de saúde, muitos idosos seguem tratamentos que incluem diversos medicamentos, pertencentes a várias clas...

  9. Fire and EMS Districts, EMS Fire Dist, Published in 2008, 1:24000 (1in=2000ft) scale, Tooele County.

    NSGIC GIS Inventory (aka Ramona) — This Fire and EMS Districts dataset, published at 1:24000 (1in=2000ft) scale, was produced all or in part from Other information as of 2008. It is described as 'EMS...

  10. Fire and EMS Districts, EMS Response Dist, Published in 2008, 1:24000 (1in=2000ft) scale, Tooele County.

    NSGIC GIS Inventory (aka Ramona) — This Fire and EMS Districts dataset, published at 1:24000 (1in=2000ft) scale, was produced all or in part from Other information as of 2008. It is described as 'EMS...

  11. Syntheses of Enantiopure Aliphatic Secondary Alcohols and Acetates by Bioresolution with Lipase B from <em>Candida antarcticaem>

    Richele P. Severino

    2012-07-01

    Full Text Available The lipase B from <em>Candida antarcticaem> (Novozym 435®, CALB efficiently catalyzed the kinetic resolution of some aliphatic secondary alcohols: (±-4-methylpentan-2-ol (1, (±-5-methylhexan-2-ol (3, (±-octan-2-ol (4, (±-heptan-3-ol (5 and (±-oct-1-en-3-ol (6. The lipase showed excellent enantioselectivities in the transesterifications of racemic aliphatic secondary alcohols producing the enantiopure alcohols (>99% <em>ee> and acetates (>99% <em>ee> with good yields. Kinetic resolution of <em>rac>-alcohols was successfully achieved with CALB lipase using simple conditions, vinyl acetate as acylating agent, and hexane as non-polar solvent.

  12. The role of common toads in the winter diet of recolonising Eurasian otters (<em>Lutra lutraem>

    Pablo García-Díaz

    2011-02-01

    Full Text Available Importanza del rospo comune nella dieta invernale di una popolazione di lontra (<em>Lutra lutraem> in espansione.
    Tramite analisi dei resti fecali, abbiamo evidenziato il ruolo fondamentale degli anfibi nella dieta invernale della lontra <em>Lutra lutraem> in stagni artificiali della Spagna nord-occidentale. I numerosi “laghi di cava” presenti nell’area umida di Ribeiras do Louro e Gandaras de Budiño sono stati monitorati nel 2007-2009. Il rospo comune (<em>Bufo bufoem> era la principale preda della lontra, costituendo l’88% della biomassa consumata, mentre il gambero americano <em>Procambarus clarkiiem> e i pesci erano prede secondarie. I nostri risultati contrastano con la ben nota preferenza della lontra per le rane rispetto al rospo. Il mantenimento della popolazione di lontra nel bacino del fiume Louro dipende strettamente dalla corretta gestione degli stagni artificiali.

  13. Regulation of Arabidopsis thaliana Em genes : role of AB15

    Carles, C.; Bies-Etheve, N.; Aspart, L.; Léon-Kloosterziel, K.M.; Koornneef, M.; Echeverria, M.; Delseny, M.

    2002-01-01

    In order to identify new factors involved in Em (a class I Late Embryogenesis Abundant protein) gene expression, Arabidopsis mutants with an altered expression of an Em promoter GUS fusion construct and a modified accumulation of Em transcripts and proteins were isolated. Germination tests on ABA sh

  14. <em>Botulinum Neurotoxinem> A Injections Influence Stretching of the Gastrocnemius Muscle-Tendon Unit in an Animal Model

    Christopher J. Tuohy

    2012-08-01

    Full Text Available <em>Botulinum Neurotoxinem> A (BoNT-A injections have been used for the treatment of muscle contractures and spasticity. This study assessed the influence of (BoNT-A injections on passive biomechanical properties of the muscle-tendon unit. Mouse gastrocnemius muscle (GC was injected with BoNT-A (<em>n> = 18 or normal saline (<em>n> = 18 and passive, non-destructive, <em>in vivoem> load relaxation experimentation was performed to examine how the muscle-tendon unit behaves after chemical denervation with BoNT-A. Injection of BoNT-A impaired passive muscle recovery (15% <em>vs.> 35% recovery to pre-stretching baseline, <em>p> < 0.05 and decreased GC stiffness (0.531 ± 0.061 N/mm <em>vs.> 0.780 ± 0.037 N/mm, <em>p> < 0.05 compared to saline controls. The successful use of BoNT-A injections as an adjunct to physical therapy may be in part attributed to the disruption of the stretch reflex; thereby modulating <em>in vivoem> passive muscle properties. However, it is also possible that BoNT-A injection may alter the structure of skeletal muscle; thus modulating the <em>in vivoem> passive biomechanical properties of the muscle-tendon unit.

  15. Arthur Ramos: intelectual em perspectiva

    Adir da Luz Almeida

    2016-03-01

    Full Text Available O trabalho constituise em resultado de pesquisa sobre o intelectual Arthur Ramos, suas reflexões teóricas e os efeitos no campo social e educativo. Arthur Ramos, intelectual complexo, multifacetado, refletiu sobre várias temáticas, pensando o Brasil como "nação" moderna, como outros intelectuais na passagem do século XIX para o século XX. Através redes de sociabilidade das quais participou e dos cargos públicos que ocupou, incluindo a chefia do Serviço de Ortofrenia e Higiene Mental do Instituto de Pesquisas Educacionais, na administração de Anísio Teixeira como Diretor de Instrução Pública, Rio de Janeiro, na década de 1930. Implanta o Serviço que tem como base a proximidade entre família, escola e comunidade, tendo como perspectiva alcançar as famílias e população pela escola. O foco é a discussão conceitual de "higiene" e "miscigenação", com atenção ao intelectual nesse debate, suas concepções, inflexões e contradições. São utilizadas como fontes algumas obras produzidas por Ramos, e arquivos sobre o SHOM, sob aguarda da Biblioteca Nacional.Palavras chave: intelectual, educação, historiografia, antropologia__________________Abstract: The work is the result of research on the intellectual Arthur Ramos, their theoretical reflections and the effects on social and educational field. Arthur Ramos, complex, multifaceted intellectual, reflected on several themes, thinking the Brazil as modern "nation", like other intellectuals in the passage from the XIX century to the XX century. Through social networks of which participated and the public office he held, including the leadership of the Ortofrenia Service and Mental Hygiene, of the Educational Research Institute, administration of Anísio Teixeira, as Director of Public Instruction, Rio de Janeiro, in the decade of 1930. Deploys the service that is based on the close the proximity between family, school and community, with the prospect to reach the families and

  16. Ceratomicose em equinos Equine keratomycosis

    Paula Diniz Galera

    2012-07-01

    Full Text Available O cavalo, dado o seu meio ambiente, está sujeito a afecções frequentes da córnea e da conjuntiva, tecidos oculares bastante expostos a bactérias e fungos, principalmente Aspergillus spp. e Fusarium spp. As ceratites ulcerativas bacterianas e fúngicas, bem como as ceratites fúngicas não ulcerativas, caracterizadas principalmente pelo abscesso estromal, são frequentes nessa espécie. Ocorrida a lesão inicial, perpetua-se um ciclo vicioso, com liberação de citocinas inflamatórias, que desencadeiam uma rápida e severa infiltração corneal por células polimorfonucleares. A córnea torna-se sujeita à destruição por enzimas proteolíticas liberadas pelos micro-organismos e por células inflamatórias, capazes de desencadear a dissolução estromal e a perfuração do bulbo ocular. O tratamento clínico para a resolução da doença corneal e o controle da uveíte reflexa deve ser agressivo e associado, muitas das vezes, à terapia cirúrgica. Este artigo discorre sobre a fisiopatologia e o tratamento da ceratomicose em equinos.Environmental and behavioral factors make horses susceptible to corneal and conjunctival lesions, since these structures are constantly exposed to bacteria and fungi specially Aspergillus spp. and Fusarium spp. Bacterial and fungal ulcerative keratitis, as well as non-ulcerative fungal keratitis such as stromal abscess, are frequent in horses. A "cascade" effect follows the initial lesion which triggers the release of inflammatory cytokines followed by an acute and severe infiltrate of polymorphonuclear cells in the cornea. The cornea becomes susceptible to the activity of proteolytic enzymes released by microorganisms and polymorphonuclear cells, resulting in stromal degradation and ocular perforation. The medical treatment targeting the corneal disease and the controlling of reflexive uveitis should be aggressive and surgical therapy should be associated in most of the cases. This paper reviews the

  17. Helminth communities of wood mouse (<em>Apodemus sylvaticusem>) on the river Avena (Calabria, southern Italy)

    Concetta Milazzo; Calogero Di Bella; Juan Carlos Casanova; Alexis Ribas; Mara Cagnin

    2011-01-01

    Helminth parasites of woodmouse <em>Apodemus sylvaticusem> were studied from May 1993 through to June 1994 on the River Avena (Calabria, southern Italy), which, as other Mediterranenan rivers, is dry for most of the year. Trapping sites were located in three different habitats of the river: slopes, shores and the riverbed. A total of 106 animals was captured and screened for the presence of helminths. Five endoparasitic species were detected: <em>Corrigia vittaem>,...

  18. Design of Higher-<em>k> and More Stable Rare Earth Oxides as Gate Dielectrics for Advanced CMOS Devices

    Yi Zhao

    2012-08-01

    Full Text Available High permittivity (<em>k> gate dielectric films are widely studied to substitute SiO2 as gate oxides to suppress the unacceptable gate leakage current when the traditional SiO2 gate oxide becomes ultrathin. For high-<em>k> gate oxides, several material properties are dominantly important. The first one, undoubtedly, is permittivity. It has been well studied by many groups in terms of how to obtain a higher permittivity for popular high-<em>k> oxides, like HfO2 and La2O3. The second one is crystallization behavior. Although it’s still under the debate whether an amorphous film is definitely better than ploy-crystallized oxide film as a gate oxide upon considering the crystal boundaries induced leakage current, the crystallization behavior should be well understood for a high-<em>k> gate oxide because it could also, to some degree, determine the permittivity of the high-<em>k> oxide. Finally, some high-<em>k> gate oxides, especially rare earth oxides (like La2O3, are not stable in air and very hygroscopic, forming hydroxide. This topic has been well investigated in over the years and significant progresses have been achieved. In this paper, I will intensively review the most recent progresses of the experimental and theoretical studies for preparing higher-<em>k> and more stable, in terms of hygroscopic tolerance and crystallization behavior, Hf- and La-based ternary high-<em>k> gate oxides.

  19. Uso de plasma rico em plaquetas em úlceras de córnea em cães

    N.B. Merlini

    2014-12-01

    Full Text Available Este trabalho teve por objetivo avaliar, clínica e macroscopicamente, o tratamento adjuvante com plasma rico em plaquetas na forma de colírio ou tampão, em úlceras de córnea de cães atendidos no Serviço de Oftalmologia Veterinária. Foram analisados 20 olhos com diagnóstico de ceratite ulcerativa, distribuídos em dois grupos experimentais. O grupo colírio (GC foi constituído por olhos tratados topicamente com colírio autólogo de plasma rico em plaquetas (PRP, e o grupo tampão (GT por olhos submetidos ao tratamento à base de tampão sólido de PRP, associado ao recobrimento com terceira pálpebra para retenção deste. Os grupos foram avaliados, por meio de avaliação clínica, macroscópica e análise da redução do defeito epitelial, em diferentes momentos, aos três, cinco, dez, 15 e 30 dias, com exceção do terceiro dia no GT. O recobrimento da terceira pálpebra foi removido no quinto dia no GT. Em ambos os grupos, houve redução dos sinais de inflamação, melhora na sensibilidade ocular e adequada reparação do defeito epitelial. Todos os olhos do GT apresentaram completa cicatrização no quinto dia e 70% no GC, atingindo a totalidade no 10º dia. O PRP na forma de colírio ou tampão é uma excelente terapia adjuvante a ser instituída no tratamento clínico da úlcera de córnea em cães, pois atua na diminuição dos sinais inflamatórios, da dor ocular e auxilia potencialmente na cicatrização do defeito epitelial.

  20. First records of the northern raccoon <em>Procyon lotorem> in Italy

    Luca Canova

    2009-02-01

    Full Text Available Riassunto Prime segnalazioni del procione <em>Procyon lotorem> in Italia In Lombardia fra il 2004 e il 2008 sono stati segnalati 10 individui di procione <em>Procyon lotorem>. La distribuzione delle osservazioni è coerente con l'areale attualmente occupato dalla specie in Europa. Il fatto che le osservazioni siano avvenute lungo il corso dell'Adda e dei canali da esso alimentati permettedi ipotizzare che la specie abbia colonizzato il paese seguendo una rotta di dispersione che connette l'area del lago di Como alla Svizzera e al corso del fiume Adda. L'osservazione di giovani suggerisce l'esistenza di una popolazione riproduttiva in Italia.

  1. Marcha em pontas idiopática em idade pediátrica

    Domingues, Sara; Melo, Cláudia; Magalhães, Catarina; Figueiroa, Sónia; Carrilho, Inês; Temudo, Teresa

    2016-01-01

    A marcha em pontas tem uma incidência de 7-24% na popu¬lação pediátrica em geral e é uma causa relativamente frequente de referenciação à consulta de neurologia pediátrica. A marcha em pontas idiopática ocorre em crianças saudáveis, sem espas¬ticidade e com reflexos osteotendinosos normais; é evidente desde o início da marcha autónoma, sempre bilateral e não pro¬gressiva. A sua etiologia é desconhecida, pelo que se trata de um diagnóstico de exclusão. Assim, na avaliação destas crian¬ças é es...

  2. Alimentazione di <em>Marmota marmotaem> in praterie altimontane delle dolomiti bellunesi

    Alessandro Rudatis; Renzo De Battisti

    2006-01-01

    Abstract The diet of <em>Marmota marmotaem> in the mountain prairie of south-eastern Italian Alps. Diet composition of two family groups of alpine marmots was investigated in two areas of the Agordino’s Dolomites (Italian Alps) in June-September 2001, by means of microscopic analysis of faeces and of direct observation of feeding activity. During the whole period of activity, a high consume of Angiosperms was co...

  3. Determinação de hemogregarina em Boa constrictor constrictor mantidos em cativeiro

    Monique A. Luz

    2012-08-01

    Full Text Available O presente estudo teve como objetivo determinar a presença de hemogregarina em boídeos mantidos em cativeiro no Estado do Pará, bem como, relacionar a hemoparasitose com pre-disposição sexual, alterações clínicas e hematológicas e a presença de ectoparasitos. Esta pesquisa teve autorização do Sistema de Autorização e Informação em Biodiversidade do Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais Renováveis para ser realizado. Utilizaram-se 19 serpentes da família Boidae mantidas em cativeiro, pertencentes ao "Museu Paraense Emilio Goeldi" (Belém/PA e "Sítio Xerimbabo" (Santo Antônio do Tauá/PA. A pesquisa de hemogregarina foi realizada em esfregaços sanguíneos examinados no aumento de 400x, enquanto que a parasitemia foi determinada contando- se 550 hemácias em aumento de 1000x. Do total de animais estudados (n=19, nove encontraram-se parasitados (47,36%, não havendo correlação entre presença de hemogregarina, pré-disposição sexual, alterações clínicas e hematológicas nas serpentes hospedeiras. A correlação da hemoparasitose foi detectada apenas quanto à presença de ectoparasitas nas serpentes, no entanto, estudos adicionais são necessários para verificar a prevalência de hemogregarinas em animais mantidos em cativeiro no Estado do Pará, visto que, existe grande lacuna de dados na literatura veterinária especializada no que diz respeito à fauna da região amazônica.

  4. New Cembrane Diterpenoids from a Hainan Soft Coral <em>Sinularia> sp.

    Yonghong Liu; Yan Peng; Xiubao Li; Xiuping Lin; Juan Liu; Xian-Wen Yang; Xuefeng Zhou; Hui Huang; Bin Yang

    2012-01-01

    Five new cembrane diterpenoids, named sinuflexibilins A–E (15), along with nine other known diterpenoids (614), have been isolated from the organic extract of a Hainan soft coral <em>Sinularia em>sp. Their structures were determined on the basis of extensive spectroscopic analyses and by comparison of their spectral data with those of related metabolites. Compoun...

  5. Melanogenesis Inhibition by Homoisoflavavone Sappanone A from <em>Caesalpinia sappanem>

    Hsiou-Yu Ding

    2012-08-01

    Full Text Available Homoisoflavanone, sappanone A, was isolated from <em>Caesalpinia sappanem> and proven to dose-dependently inhibit both melanogenesis and cellular tyrosinase activity via repressing tyrosinase gene expression in mouse B16 melanoma cells. To our knowledge, sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. Our results give a new impetus to the future search for other homoisoflavanone melanogenesis inhibitors.

  6. Desenvolvimento puberal em meninas tratadas de LLA

    Monteiro I.M.M.

    1998-01-01

    Full Text Available OBJETIVO: Com o objetivo de avaliar o desenvolvimento puberal após o tratamento de leucemia linfóide aguda (LLA na infância, foi realizado um estudo retrospectivo, em meninas tratadas de janeiro de 1980 a janeiro de 1991, no Centro de Investigações Hematológicas "Dr. Domingos A. Boldrini", em Campinas-SP. CASUÍSTICA E MÉTODO: Foram selecionadas 42 meninas, tratadas antes da puberdade com quimioterapia sistêmica e intratecal e radioterapia cranial, utilizando doses de 18 ou 24 Grays (Gy. RESULTADOS: As idades médias da telarca, pubarca e menarca foram inferiores às do grupo-controle, embora com significância estatística apenas para a idade da telarca. Não houve diferenças entre os grupos tratados com 18 ou 24Gy. As meninas tratadas antes dos cinco anos de idade apresentaram idade média da menarca estatisticamente inferior àquelas tratadas após cinco anos e em relação ao grupo-controle. CONCLUSÃO: Os resultados mostraram que o desenvolvimento puberal em meninas tratadas de LLA na infância foi mais precoce que o de meninas saudáveis.

  7. EMS – Elektron Musik Studion in Stockholm

    Groth, Sanne Krogh

    2015-01-01

    In 1964 the electronic music studio EMS, Stockholm opened as a conventional analogue studio. The primary intension with the institution was to build the world’s most advanced hybrid studio and to conduct an international research program into sound and sound perception. With financial support from...

  8. A letra em seu devido lugar

    Musso Garcia Greco

    2005-12-01

    Full Text Available A oficina de letras (letra, segundo Lacan busca criar um ponto de ancoragem para o sujeito psicótico, desconstruindo seu saber absoluto, através da articulação literatura e psicanálise, em sua função metonímica.

  9. Badger <em>Meles melesem> and Fox <em>Vulpes vulpesem> food in agricultural land in the western Po Plain (Italy

    Luca Canova

    1994-05-01

    Full Text Available Abstract Fox and badger diets were studied by means of scat analysis in agricultural land in northern Italy. Earthworms and corn were the staple food for the badger, while foxes fed mainly on animal food (birds and mammals. Dietary overlap between the two species was low. Fox diets were substantially similar to those in north-central Europe and other areas of Italy. Badger diets differed from those in mediterranean areas of Italy and were similar to diets of north European populations. Riassunto Alimentazione di Tasso <em>Meles melesem> e Volpe <em>Vulpes vulpesem> in aree agricole della Pianura Padana occidentale - La dieta di tasso e volpe in un'area agricola della Pianura Padana occidentale è stata studiata mediante analisi delle feci. Lombrichi e mais rappresentano la principale fonte alimentare per il tasso, mentre la dieta della volpe è basata prevalentemente su uccelli e mammiferi. La sovrapposizione alimentare fra le due specie è ridotta. La dieta della volpe è simile a quella delle popolazioni dell'Europa centrale e settentrionale; la dieta del tasso differisce nettamente da quella delle popolazioni italiane che vivono in ambiente mediterraneo.

  10. A robust approach to Meta-EMS

    Swinkels, R.H.A.

    2012-01-01

    This study was concerned with the meta-Energy Mediation System (meta-EMS) problem. We consider several companies from the horticulture industry, for which we have to match supply and demand of different commodities a few days ahead. We have introduced the problem and considered the relevant literatu

  11. Enrichment and Purification of Syringin, Eleutheroside E and Isofraxidin from <em>Acanthopanax> <em>senticosus> by Macroporous Resin

    Yuangang Zu

    2012-07-01

    Full Text Available In order to screen a suitable resin for the preparative simultaneous separation and purification of syringin, eleutheroside E and isofraxidin from <em>Acanthopanax> <em>senticosus>, the adsorption and desorption properties of 17 widely used commercial macroporous resins were evaluated. According to our results, HPD100C, which adsorbs by the molecular tiers model, was the best macroporous resin, offering higher adsorption and desorption capacities and higher adsorption speed for syringin, eleutheroside E and isofraxidin than other resins. Dynamic adsorption and desorption tests were carried out to optimize the process parameters. The optimal conditions were as follows: for adsorption, processing volume: 24 BV, flow rate: 2 BV/h; for desorption, ethanol–water solution: 60:40 (v/v, eluent volume: 4 BV, flow rate: 3 BV/h. Under the above conditions, the contents of syringin, eleutheroside E and isofraxidin increased 174-fold, 20-fold and 5-fold and their recoveries were 80.93%, 93.97% and 93.79%, respectively.

  12. Uso de digital em idosos admitidos em unidade de geriatria de um hospital geral

    Cunha Ulisses Gabriel de Vasconcelos

    1998-01-01

    Full Text Available OBJETVO: Detectar a freqüência da prescrição do digital, assim como as suas indicações, em idosos admitidos em unidade de geriatria de um hospital geral. MÉTODOS: Foram investigados, consecutivamente, 130 pacientes não selecionados, de ambos os sexos (100 mulheres e 30 homens, com idades > ou = 65 (média 80±9 anos. Os pacientes foram avaliados através de exame clínico completo, rotina básica de sangue, radiografia simples de tórax, eletrocardiograma e ecocardiograma Doppler. Baseados na avaliação clínica e exames complementares, o uso do digital foi considerado adequado, questionável ou inadequado. RESULTADOS: Estavam em uso de digital 27,6% dos pacientes. A indicação foi considerada adequada em 36,1%, questionável em 11,1% e inadequada em 52,7%. CONCLUSÃO: Uma alta prevalência de prescrição do digital foi detectada nos idosos admitidos, sendo que a maior parte a adotava por razões consideradas inadequadas ou questionáveis. Devido ao risco aumentado de intoxicação digitálica nessa faixa etária, a droga deveria ser prescrita sob indicações mais criteriosas.

  13. The Italian Action Plan for the endangered Eurasian otter <em>Lutra lutraem>

    Anna Loy

    2010-08-01

    Full Text Available Abstract
    Although recent evidence of the species recovery has been reported for many European countries, in Italy the Eurasian otter <em>Lutra lutraem> is still considered endangered. Otter populations are confined to few river basins in the southern part of the peninsula and these are both geographically and genetically isolated from other European populations. This critical situation led the Italian Ministry of Environment to promote the production of an Action Plan for the otter in Italy, whose methods, aims and actions are briefly summarized.

    Riassunto
    Il Piano d'Azione Nazionale per la Lontra <em>Lutra lutraem>
    Nonostante i segnali di recupero segnalati in molti paesi europei, la lontra <em>Lutra lutraem> è ancora una delle specie più minacciate della fauna italiana, in virtù delle piccole dimensioni della popolazione e del suo isolamento , sia geografico, sia genetico, dal resto delle popolazioni europee. Sulla base di queste considerazioni il Ministero dell’Ambiente e della Tutela del territorio e del Mare ha recentemente promosso la realizzazione di un Piano d’Azione Nazionale per la Conservazione della Lontra, i cui contenuti, obiettivi, e azioni sono riassunti in questo lavoro.

    doi:10.4404/hystrix-21.1-4483

  14. Preliminary study on the acoustic communication of captive otters (<em>Lutra lutraem>

    Claudio Gnoli

    1995-12-01

    Full Text Available Abstract The study was conducted on captive otters (<em>Lutra lutraem> in a large enclosure (1.64 ha in area. Data on different kind of sounds related to specific behaviours were recorded by videocamera. Furthermore, sounds were collected by tape recorder, analysed by spectrograph and represented by spectrograms. A general pattern of the vocalizations of otter has been obtained, in order to understand the acoustic communication system of the species. The main sound categories were blows, mewings and cries in an aggressive context, murmurs and two kinds of whistles in a social context. Riassunto Studio preliminare sulla comunicazione acustica della lontra (<em>Lutra lutraem> in cattività - Lo studio è stato condotto su lontre (<em>Lutra lutraem> tenute in cattività in un ampio recinto (1,64 ha. Attraverso riprese effettuate tramite videocamera, sono stati raccolti dati sull'emissione delle diverse tipologie di suoni in determinati contesti comportamentali. Inoltre, per mezzo di un magnetofono sono state registrate alcune manifestazioni sonore, successivamente analizzate mediante sonografo e rappresentate in forma di spettrogrammi. In questo modo è stato ottenuto un quadro della gamma di vocalizzazioni della lontra che può contribuire alla comprensione del suo sistema di comunicazione acustica. Le principali categorie di suoni individuate consistono in sbuffi, miagolii e grida nell'ambito aggressivo, mormorii e due tipi di fischi nell'ambito del contatto sociale.

  15. Locas al Rescate: The Transnational Hauntings of Queer <em>Cubanidad>

    Lázaro Lima

    2011-12-01

    Full Text Available

    “Locas al Rescate: The Transnational Hauntings of Queer <em>Cubanidad>” (originally published in <em>Cuba Transnationalem> offers a significant contribution both to transnational American Studies and to gender studies. In telling the insider story of the alternative identity formation, practices, and forms of “rescue” initiated by the affective activism of the Cuban American society in drag in 1990s Miami/South Beach, Lima resuscitates the liberatory gestures of a subculture defined by its pursuit of its own acceptance, value, and freedom. With their aesthetic and political life on a raft, the gay micro-communities inside Cuban America asserted their own islandic space, Lima observes, performing “takeovers” in and of parks and bars and beaches—creating a post-Habermasian sphere of public activism focused on private parts, saving themselves from AIDS, from the disaffection and disaffiliation of the right-wing Cuban immigrant community, and from the failure of their own yearning to belong, to be wanted, to be embodied as the figure of their compelling <em>Cubanidad>. Against the hegemony of the invented collective politics of the sacrificing immigrants whose recognition of the queer side of being (of a being constituted by identity loss is yet to come, Lima suggests a spectral return—a personal and transnational reckoning of those whose lives the dream of freedom drowned.

  16. A new karyotype of <em>Calomyscus> from the Khorasan Province, Iran

    Esmaeeli Somayeh

    2008-07-01

    Full Text Available Abstract We report a new karyotype of <em>Calomyscus> from two localities of the Khorasan Province (Aghdarband, 36° 11’ 3”N, 60° 44’ 6” E and Khajemorad, 36° 8’ 5” N, 59° 41’ 58” E. Chromosomes were examined by conventional staining and C-banding techniques. The diploid chromosome number (2n and the fundamental autosomal arm number (FNa were 44 and 60 respectively. The autosomal set consisted of 12 pairs of telocentrics, 5 pairs of acrocentrics and 4 pairs of sub-metacentrics. Both heterosomes were small telocentrics. Riassunto Un nuovo cariotipo del genere <em>Calomyscus> dalla provincia di Khorasan, Iran. Si descrive un nuovo cariotipo appartenente al genere <em>Calomyscus>, scoperto in due località della provincia di Khorasan (Aghdarband, 36° 11’ 3”N, 60° 44’ 6” E e Khajemorad, 36° 8’ 5” N, 59° 41’ 58” E. I cromosomi sono stati analizzati con le tecniche standard di colorazione e bandeggio. Il numero diploide di cromosomi (2n e il numero fondamentale di bracci autosomici sono risultati pari a 44 e 60 rispettivamente. Il set di cromosomi autosomici è composto da 12 paia di telocentrici, 5 di acrocentrici e 4 di sub-metacentrici. Entrambi i cromosomi sessuali si presentano come piccoli telocentrici.

  17. Resposta da alface à adubação nitrogenada com diferentes compostos orgânicos em dois ciclos sucessivos = Response of lettuce to nitrogen fertilization with different organic composts in two successive cycles

    Francisca Alcivania de Melo Silva

    2010-01-01

    Full Text Available Os objetivos deste trabalho foram avaliar a produção de alface em ambiente protegido, utilizando diferentes compostos orgânicos como fonte de nitrogênio, e seu efeito residual em dois ciclos sucessivos. O experimento foi conduzido entre os meses de fevereiro e maio de 2005, em casa-de-vegetação com ventilação e temperatura controlados, utilizando vasos de 3,5 L e solo classificado como Latossolo Vermelho Escuro. Foram utilizados compostos orgânicos produzidos a partir da mistura de resíduos do processamento de quatro plantas medicinais e esterco bovino. Os compostos C1, C2, C3 e C4 nas doses 30, 60, 90 e 120 t ha-1 constituíram os tratamentos dispostos em delineamento inteiramente casualizado, com quatro repetições e uma testemunha (adicional. Foram determinados: matéria fresca da parte aérea (MFPA; massa de matéria seca da parte aérea (MSPA. Os compostos aplicados supriram satisfatoriamente as necessidades de nitrogênio da cultura, no primeiro ciclo, dispensando o uso de fertilizante mineral. A composição dos materiais aplicados influenciou significativamente a produção de alface no primeiro ciclo, promovendo efeito residual no segundo ciclo, porém em menores proporções.The objectives of this work were to evaluate the production of lettuce in a protected environment, using different organic composts as nitrogen source and its residual effect in two successive cycles. The experiment was conducted between February and May of 2005, at a greenhouse with controlled ventilation and temperature, using 3.5 L vases and ground classified as Dark Red Latossol. Organic composts produced from the mixture of residues of the processing of four medicinal plants and cattle manure were used. The composts C1, C2, C3 and C4 in doses 30, 60, 90 and 120 t ha-1 composed the treatments, set in an entirely randomized design, with four repetitions and one control (additional treatment. The following were determined: freshmatter of aerial part

  18. Evaluation of Antioxidant and Immunity-Enhancing Activities of <em>Sargassum pallidumem> Aqueous Extract in Gastric Cancer Rats

    Shen-Kang Zhou

    2012-07-01

    Full Text Available The effect of <em>Sargassum pallidumem> (brown seaweed aqueous extract on the immunity function and antioxidant activities in was studied gastric cancer rats. Treatment with <em>Sargassum pallidumem> aqueous extract at oral doses 400, 600 or 800 mg/kg body weight was found to provide a dose-dependent protection against <em>Nem>-methyl-N′-nitro-N>-nitrosoguanidine (MNNG-induced immunity damage and oxidative injury by enhancing serum interleukin-2 (IL-2, interleukin-4 (IL-4, interleukin-10 (IL-10 levels, decreasing interleukin-6 (IL-6, interleukin-1β (IL-1β, tumor necrosis factor-alpha (TNF-α levels, preserving normal antioxidant enzymes activities, and by inhibiting lipid peroxidation in gastric mucosa. It can be concluded that <em>Sargassum pallidumem> aqueous extract may enhance the immunity and antioxidant activities in gastric cancer rats.

  19. Babesiose cerebral em bovinos: 20 casos

    Rodrigues Aline

    2005-01-01

    Full Text Available Num estudo retrospectivo de 1.071 necropsias de bovinos, foram encontrados 20 casos de babesiose cerebral confirmados pelo exame de esfregaços do córtex telencefálico. A maioria desses casos ocorreu no verão, em bovinos adultos de raças européias ou suas cruzas. Além dos sinais clínicos neurológicos, observou-se hemoglobinúria, anorexia, febre, taquicardia, taquipnéia e queda na produção de leite. O hemograma realizado em cinco bovinos afetados revelou acentuada anemia regenerativa; em média, 20% dos eritrócitos estavam parasitados por Babesia bovis. Na necropsia de todos os casos, a substância cinzenta dos córtices telencefálico e cerebelar e dos núcleos da base era consistente e caracteristicamente róseo-cereja. Essa coloração devia-se ao seqüestro de eritrócitos nos capilares encefálicos. Nesses eritrócitos, podiam-se observar, tanto em esfregaços do córtex como em preparações histológicas do encéfalo, microorganismos com morfologia compatível com B. bovis. Outros achados de necropsia incluíam hemoglobinúria, rins vermelho-escuros, hepatoesplenomegalia, fígado vermelho-alaranjado, icterícia, hemorragias epicárdicas e endocárdicas e edema e congestão dos linfonodos mesentéricos.

  20. On the occurrence of <em>Myotis alcathoeem> von Helversen and Heller, 2001 in Austria

    Friederike Spitzenberger

    2008-07-01

    Full Text Available Abstract In 2006, one male and two females of <em>Myotis alcathoeem> were captured in mistnets at two localities in southern Burgenland, Austria. For two individuals the preliminary specific identification based on external measurements was confirmed by sequencing parts of the mitochondrial ND1 gene. Across the sequenced region, the two analysed bats share a 100% identical haplotype that corresponds to the haplotype found in Hungarian bats identified as <em>M. alcathoeem>, and was found also in Spanish, French and Slovakian samples. The three animals from Burgenland constitute the first records of this species in Austria. Age related differences in pelage and membrane colouration and measurements of <em>M. alcathoeem> are described. A comparison of skull length measurements between <em>M. alcathoeem> and <em>Myotis mystacinusem> seems to indicate that the interspecific difference in external dimensions is not reflected in skull dimensions. The Austrian localities of <em>M. alcathoeem> belong to the Pannonian part of the range like findings in Slovakia and Hungary. Riassunto Sulla presenza di <em>Myotis alcathoeem> von Helversen and Heller, 2001 in Austria. Nel 2006, due maschi e una femmina di <em>Myotis alcathoeem> sono stati catturati tramite mist-nets in due località del Burgenland meridionale, Austria. Per due individui, l’identificazione preliminare su basi morfologiche è stata confermata dall’analisi del gene mitocondriale ND1. Nella sequenza analizzata, gli aplotipi dei due individui coincidono al 100% e corrispondono a quelli evidenziati in soggetti spagnoli, francesi e sloveni. I tre esemplari del Burgenland rappresentano la prima segnalazione certa di questa specie per l’Austria. Vengono descritte alcune differenze nella colorazione della pelliccia e del patagio tra adulti e subadulti. Il confronto delle misure del cranio di <em>M. alcathoeem> e <em

  1. SENSIBILIDADE DE OVOS DE Ceratitis capitata (WIED., 1824) IRRADIADOS EM DIETA ARTIFICIAL E EM FRUTOS DE MANGA (Mangifera indica L.)

    Raga, A.; YASUOKA S.T; E.O AMORIM; SATO M.E; SUPLICY FILHO N; FARIA J.T. de

    1996-01-01

    O objetivo deste trabalho foi determinar as doses de radiação gama que impedissem a emergência de adultos de Ceratitis capitata, a partir de ovos irradiados em dieta artificial e em frutos de manga. Quinhentos ovos de 6, 12, 24 e 48 horas de idade foram irradiados em cada dose. A infestação artificial de ovos ocorreu em mangas das cultivares Haden, Tommy Atkins ou Keitt. Um aumento da radioresistência de ovos foi observado durante o desenvolvimento embrionário, e para ovos de 48 horas em diet...

  2. Adubos verdes e adubação mineral nitrogenada em cobertura na cultura do trigo em plantio direto

    Anísio da Silva Nunes; Luiz Carlos Ferreira de Souza; Fábio Martins Mercante

    2011-01-01

    Objetivou-se neste trabalho avaliar o efeito do cultivo de adubos verdes, associados a doses de nitrogênio (N) em adubação de cobertura, no desempenho agronômico da cultura do trigo em sistema plantio direto. O experimento foi realizado em Dourados (MS), Brasil, em delineamento de blocos casualizados, com os tratamentos dispostos em esquema de parcelas subdivididas e quatro repetições. As parcelas foram constituídas pelos adubos verdes: ervilhaca peluda (Vicia villosa), crotalária (Crotalaria...

  3. Asociación entre el insecticida biológico (<em>Baccilus thuringiensisem>) con subdosajes de regulador del crecimiento para controlar <em>Anticarsia gemmatalisem> (Lepidoptera: Noctuidae) en la soja Associação entre inseticida biológico (<em>Baccilus thuringiensisem>) com subdosagens de regulador de crescimento para o controle da <em>Anticarsia gemmatalisem> (Lepidoptera: Noctuidae) na cultura da soja

    Mauricio Zanovello Schuster; Cristhiane Rohde

    2012-01-01

    Na cultura da soja no Brasil <em>Anticarsia gemmatalisem> é a praga mais importante dentre as lagartas desfolhadoras. Considerando que os inseticidas biológicos e reguladores de crescimento de insetos têm vantagens ecotoxicologicas sobre os inseticidas neurotóxicos, o objetivo do trabalho foi avaliar a eficiência de um produto a base <em>B. thuringiensisem> em mistura com subdosagens do regulador de crescimento para o controle dessa praga. ...

  4. Commensal <em>Pseudomonas> Species Isolated from Wastewater and Freshwater Milieus in the Eastern Cape Province, South Africa, as Reservoir of Antibiotic Resistant Determinants

    Okoh, Anthony I.; Mvuyo Tom; Anibal Sosa; Igbinosa, Isoken H.; Nwodo, Uchechukwu U.

    2012-01-01

    <em>Pseudomonas> species are opportunistic pathogens with implications in a wide range of diseases including cystic fibrosis and sickle cell anaemia. Because of their status as multidrug resistant (MDR) and extremely drug resistant (XDR) bacteria <em>Pseudomonas> species represent a threat to public health. Prevalence, antibiogram and associated antibiotic resistant genes of <em>Pseudomonas> species isolated from freshwater and mixed liquor envi...

  5. Risk-Association of <em>CYP11A1em> Polymorphisms and Breast Cancer Among Han Chinese Women in Southern China

    Minying Sun

    2012-04-01

    Full Text Available Exposure to endogenous sex hormones has been reported as a risk factor for breast cancer. The <em>CYP11A1em> gene encodes the key enzyme that catalyzes the initial and rate-limiting step in steroid hormone synthesis. In this study, the associations between single nucleotide polymorphisms (SNPs in <em>CYP11A1em> and breast cancer susceptibility were examined. Six SNPs in <em>CYP11A1 em>were genotyped using the MassARRAY IPLEX platform in 530 breast cancer patients and 546 healthy controls. Association analyses based on a χ2 test and binary logistic regression were performed to determine the odds ratio (<em>OR> and 95% confidence interval (95% <em>CI> for each SNP. Two loci (rs2959008 and rs2279357 showed evidence of associations with breast cancer risk. The variant genotype C/T-C/C of rs2959008 was significantly associated with a decreased risk (age-adjusted<em> ORem>, 0.75; 95% <em>CI>, 0.58–0.96; <em>P em>= 0.023 compared with the wild-type TT. However, the homozygous TT variant of rs2279357 exhibited increased susceptibility to breast cancer (age-adjusted<em> ORem>, 1.44; 95% <em>CI>, 1.05–1.98; <em>P em>= 0.022. The locus rs2959003 also showed an appreciable effect, but no associations were observed for three other SNPs. Our results suggest that polymorphisms of <em>CYP11A1em> are related to breast cancer susceptibility in Han Chinese women of South China.

  6. Use of trophic resources and forest habitats by the genus <em>Martes> in Adamello-Brenta Park (Central Italian Alps)

    Paolo Pedrini; Claudio Prigioni; Gilberto Volcan

    1995-01-01

    Abstract Habitat use and diet of genus <em>Martes> (<em>M. martesem> and <em>M. foinaem>) were studied in alpine forest habitat (Adamello-Brenta Park, Central Italian Alps) from July 1991 to September 1992. Marten scats were looked for along 3 transects representative of 5 forest habitats in order to analyse seasonal variations in habitat selection. The food habits were studied analysing 225 scats collected along the tr...

  7. Reduced Photoinhibition under Low Irradiance Enhanced Kacip Fatimah (<em>Labisia pumila em>Benth) Secondary Metabolites, Phenyl Alanine Lyase and Antioxidant Activity

    Jaafar, Hawa Z. E.; Mohd Hafiz Ibrahim

    2012-01-01

    A randomized complete block design experiment was designed to characterize the relationship between production of total flavonoids and phenolics, anthocyanin, photosynthesis, maximum efficiency of photosystem II (Fv/Fm), electron transfer rate (Fm/Fo), phenyl alanine lyase activity (PAL) and antioxidant (DPPH) in <em>Labisia pumilaem> var. <em>alata,> em>under four levels of irradiance (225, 500, 625 and 900 µmol/m2/s) for...

  8. Strategie predatorie di <em>Crocidura leucodonem> (Hermann, 1780 in condizioni controllate: dati preliminari

    T. Bonacci

    2003-10-01

    Full Text Available Lo scopo principale di questo lavoro è stato quello di verificare, in condizioni controllate, il comportamento predatorio esibito da <em>Crocidura leucodonem> (Hermann,1780 nei confronti di diverse specie di Artropodi, nonché la capacità di vanificare le difese chimiche di alcune di esse. Le prede utilizzate appartengono a numerosi ordini di Artropodi (Coleotteri, Chilopodi, Isopodi, Emitteri sistemati in terrari di allevamento in cella termica (T = 22-24° C; L/D: 18/6. Le crocidure (n=2 provenienti dal Massicio del Pollino (1200 m s.l.m.; ottobre 2002 sono state allevate in terrario a T ambiente. Le osservazioni (Tmedio oss. 45 minuti, registrate con l?ausilio di una videocamera, sono state condotte in laboratorio dal 29/10/02 al 06/03/03, utilizzando arene sperimentali collegate al terrario di allevamento delle crocidure. I test sono stati condotti sia con gli animali nutriti che a digiuno. Gli esemplari di <em>Crocidura leucodonem> nutriti hanno mostrato una marcata preferenza per specie di Carabidi non protette, Diplopodi (ignorati invece da altre specie di Soricidae, Isopodi e larve di Coleotteri, mentre i Carabidi con difese chimiche, o loro mimi, nelle fasi iniziali dell?esperimento venivano annusati ma mai attaccati. Le crocidure a digiuno, al contrario, consumavano qualsiasi preda venisse loro offerta, attaccando anche grossi carabidi. La latenza di attacco registrata nei confronti di prede non protette è risultata essere sempre notevolmente inferiore rispetto a quella di specie protette con ?warning colors? e ?warning odors?, e che presentano, inoltre, la caratteristica del movimento lento (sindrome della difesa chimica o CDS; Whitman <em>et al.em> 1985 attraverso cui riescono efficacemente a difendersi dagli attacchi dei predatori naturali. Dopo una fase che si può ritenere di apprendimento, le crocidure hanno iniziato ad attaccare e consumare anche prede quali i Coleotteri bombardieri (<em>Brachinus> spp

  9. Sorteio de domicílios em favelas em inquéritos por amostragem

    Maria Cecilia Goi Porto Alves

    2011-12-01

    Full Text Available OBJETIVO: Identificar vantagens e desvantagens do uso de segmentos em relação ao sorteio feito a partir da lista completa de endereços, para o sorteio de domicílios em amostragem por conglomerados em múltiplos estágios em favelas. PROCEDIMENTOS METODOLÓGICOS: Estudo qualitativo realizado em quatro favelas sorteadas no Inquérito de Saúde do Município de São Paulo, SP, 2008, nas quais foram aplicadas as duas técnicas. Foram realizados grupos focais com pesquisadores de campo - "arroladores" e entrevistadores do inquérito. Os conteúdos das conversações foram analisados, agrupados em categorias e organizados em núcleos temáticos. ANÁLISE DOS RESULTADOS: A utilização de segmentos de domicílios foi associada a numerosas vantagens e poucas desvantagens. Entre as vantagens, constaram a rapidez e facilidade na elaboração do cadastro de endereços e na localização e identificação de domicílios na etapa de realização das entrevistas, maior segurança dos entrevistadores e da população, maior acesso aos entrevistados, maior estabilidade e maior cobertura do cadastro produzido, e menor ocorrência de erros na identificação dos domicílios sorteados. CONCLUSÕES: A construção de cadastro de domicílios por meio da criação de segmentos é vantajosa em relação à listagem completa de endereços, quando feita em favelas. Por ter se mostrado uma opção econômica e fácil de ser aplicada, constitui alternativa para a simplificação do processo de amostragem em áreas com as suas características de desorganização e adensamento de domicílios.

  10. Estudos sobre a Esquistosomose em Pernambuco, Brasil

    Aggeu Magalhães

    1940-01-01

    Full Text Available Os autores referem os resultados dos estudos sobre esquistosomose realisados, em Pernambuco, de Novembro de 1938 a Dezembro de 1939. Não se extendem em discussão, nem comentarios, tampouco, relacionam suas verificações com o que já foi relatado sobre o assunto em trabalhos nacionais e estrangeiros, pelo fato de que, não se trata de um resultado definitivo e sim de atividades que irão proseguir. Os estudos sistematicos em torno da endemia esquistosomica foram executados em duas localidades diversas pela população e pela situação geografica e ecologica. Pontezinha é uma povoação de 1200 habitantes localizada proximo a um conjunto de charcos e lagõas de agua dôce onde pululam caramujos do tipo olivaceus de Spix, e apresenta uma taxa de infestação de 21,4% para individuos do sexo masculino, e de 14,7% para os do sexo feminino. A distribuição por grupos de idade mostra que a incidencia cresce até o grupo de 16 a 20 anos de idade, quando atinge a percentagem de 37,8%, para decrescer em seguida. Em Vitoria a incidencia foi maior nos indivíduos do sexo feminino, atingindo a taxa de 41,4%, dando o sexo masculino a taxa de 36,9%. Por idade a percentagem maxima é atingida pelo grupo de 11 a 15 anos. Vitoria é uma cidade de 1500 habitantes, construida á margem do rio Tapacurá, onde se encontram numerosos caramujos do tipo centimetralis Lutz. A divergencia de incidencia corre por conta dos habitos da população e pela utilização que ela faz do rio, sendo maior em Vitoria porque a proximidade do rio facilita o uso de suas aguas para banho e serviços domesticos, condicionando este ultimo fato, a maior infestação das mulheres. O estudo da frequencia da infestação dos caramujos por cercarias de diversos trematodios, permite suspeitar uma relação inversa entre a taxa de infestação e o diametro maximo atingido pelos caramujos, parecendo este fato confirmar os trabalhos de Vianna Martins sobre a identidade dos hospedeiros

  11. Hydroponic lettuce production in different concentrations and flow rates of nutrient solution Produção de cultivares de alface em sistema NFT variando concentração e vazão da solução

    Gláucio da C Genuncio

    2012-09-01

    Full Text Available The objective of this study was to evaluate the accumulation of fresh weight of hydroponic lettuce in terms of ionic concentrations and flow rates of nutrient solution. This work consisted of three experiments in NFT hydroponic system, conducted between July and September 2006. Lettuce cultivars Lucy Brown, Izabela and Veneza were grown in different ionic concentrations of the 100, 75 and 50% and flow rates of 1.50, 1.00 and 0.75 L min-1. Fresh weight gains were observed for Lucy Brown when grown on 100% of the ion concentration and a flow rate of nutrient solution of 1.0 L min-1. Greater fresh mass was observed for cvs. Izabela and Veneza under the flow rate of 1.5 L min-1. A general analysis of the data allows us to conclude that the application of nutrient solution at a flow rate of 1.5 L min-1, as well as 100% of the ionic concentration is effective to increase the fresh weight of the aerial part of cvs. Lucy Brown, Izabela and Veneza when grown in hydroponics.O objetivo deste trabalho foi avaliar o acúmulo de massa fresca em cultivares de alface hidropônica em função de concentrações iônicas e de vazões de solução nutritiva. O trabalho consistiu em três experimentos em sistema hidropônico NFT, conduzidos entre julho e setembro de 2006. Cultivares de alface Lucy Brown, Izabela e Veneza foram crescidas em concentrações iônicas de 100, 75 e 50% e vazões de 1,50; 1,00 e 0,75 L min-1. Ganhos de massa fresca foram observados para Lucy Brown quando cultivada a 100% da concentração iônica e a uma vazão de solução nutritiva acima de 1,0 L min-1. Para Izabela e Veneza maiores massas frescas foram observadas em vazão de 1,5 L min-1 e 100% de concentração iônica. Uma análise geral dos dados nos permite concluir que a aplicação da solução nutritiva a uma vazão de 1,5 L min-1, assim como 100% da concentração iônica é eficiente para acréscimos de massa fresca de parte aérea para cultivares Lucy Brown, Izabela e Veneza

  12. Comportamento produtivo de caupi em regimes irrigado e de sequeiro em Petrolina e Juazeiro

    SANTOS CARLOS ANTÔNIO FERNANDES

    2000-01-01

    Full Text Available O caupi (Vigna unguiculata (L. Walp. é a cultura de grãos mais importante da região Semi-Árida brasileira. O objetivo deste trabalho foi avaliar a adaptabilidade e a estabilidade produtiva de 18 genótipos de caupi em regimes irrigado e de sequeiro, em quatro anos (1995 a 1998, nos Municípios de Petrolina, PE, e Juazeiro, BA. Os genótipos compuseram dois experimentos repetidos cinco vezes em delineamento de blocos casualizados, com quatro repetições. A produção de grãos foi corrigida por covariância no estande ideal de plantas e submetida a análises estatísticas. A presença de variações na fertilidade do solo, no manejo e no quadro pluviométrico, alterou o comportamento produtivo dos genótipos (P<0,01. O genótipo Balinha, selecionado e mantido por pequenos produtores, produziu 1.779 kg/ha em áreas irrigadas, comportamento, este, superior ou similar ao de cultivares das instituições de pesquisa. Em regime de sequeiro, os resultados indicam genótipos superiores, como a cultivar EPACE 10, com 1.343 kg/ha e a linhagem TE 901781F, com 1.176 kg/ha. A cultivar EPACE 11 apresentou bom comportamento produtivo, tanto em regime de sequeiro como em regime irrigado, com 1.497 kg/ha. Esses resultados indicam a necessidade do desenvolvimento de genótipos de caupi específicos para diferentes ambientes, com ênfase especial para áreas irrigadas.

  13. Prolapso vaginal e uterino em ovelhas

    Maíra Bianchi R. Alves

    2013-02-01

    Full Text Available O presente trabalho objetivou realizar um estudo retrospectivo sobre os prolapsos vaginal e uterino em ovelhas atendidas no Serviço de Clínica de Bovinos e Pequenos Ruminantes (CBPR da FMVZ/USP no período compreendido entre 2000 a 2010, no qual, foram atendidas 56 ovinos com problemas inerentes ao sistema reprodutivo, dessas, 25 apresentaram prolapso vaginal ou uterino (44,6%. O prolapso vaginal total foi o de maior frequência (72%. As ovelhas acometidas, em sua maioria, possuíam idade superior a quatro anos (64%, eram sem raça definida (44% ou da raça Ile de France (40%. As manifestações clínicas observadas durante a maioria dos atendimentos foram: taquipnéia, taquicardia, mucosas oculares avermelhadas indicando estado de toxemia, decúbito esternal ou lateral, apatia e anorexia. O tratamento instituído para todos os casos foi a limpeza, desinfecção e reintrodução do órgão prolapsado. A sutura de Bühner foi feita em 84% dos casos e a histeropexia em um caso (4%. A evolução foi satisfatória em 80% dos casos atendidos, nos demais casos (20% observou-se óbito da fêmea acometida. Do total de óbitos, os prolapsos vaginais foram responsáveis por 60% (3/5 e os prolapsos uterinos por 40% (2/5. A etiologia dos prolapsos não foi definida nos casos atendidos, sendo esses associados com o período pós-parto em sua maioria (56%, provavelmente associados com quadros de hipocalcemia, altas concentrações séricas de estrógeno e hipertonia uterina. Além disso, a predisposição genética não pode ser descartada.

  14. Algoritmo de Gower na estimativa da divergência genética em germoplasma de pimenta The Grower's algorithm on the estimate of genetic diversity in chili pepper germoplasm

    Maria da Cruz CL Moura

    2010-06-01

    Full Text Available A estimativa da variabilidade genética existente em um banco de germoplasma é importante não só para a conservação dos recursos genéticos, mas também para sua utilização no melhoramento de plantas. Os acessos de um banco são estudados com base em descritores quantitativos e qualitativos. Porém, nem sempre esses dados são analisados simultaneamente. O presente trabalho teve como objetivo estudar a divergência genética entre 56 acessos de Capsicum chinense procedentes da Coleção de Germoplasma da Universidade Estadual do Norte Fluminense Darcy Ribeiro, com base em 44 descritores morfoagronômicos, 37 qualitativos e sete quantitativos, utilizando-se a análise conjunta baseada no algoritmo de Gower. Utilizou-se o delineamento inteiramente ao acaso, com três repetições e três plantas por parcela. As plantas estudadas cresceram em vasos de 5 L. Houve variabilidade fenotípica entre os acessos de pimenta estudados, principalmente nos frutos, que mostraram diferenças acentuadas em tamanho, formato, coloração, teores de sólidos solúveis totais e vitamina C. O método aglomerativo utilizado foi UPGMA por ter maior coeficiente de correlação cofenética (r = 0,82. Os acessos estudados dividiram-se em seis grupos. O agrupamento com base na distância de Gower revelou maior eficiência na disjunção dos genótipos quando foram utilizadas as variáveis qualitativas em comparação às quantitativas, indicando uma maior contribuição daquelas na explicação dos agrupamentos. A análise conjunta dos dados quantitativos e qualitativos resultou em maior eficiência na determinação da divergência genética entre os acessos avaliados, sendo uma alternativa viável e uma ferramenta importante para o conhecimento da variabilidade em bancos de germoplasma.The estimation of genetic variability in germplasm collections is important not only for the conservation of genetic resources, but also for plant breeding purposes. Accessions in a

  15. LESÕES FOLIARES EM MUDAS DE PEQUIZEIRO (Caryocar brasiliensis Cambess LEAF LESIONS OF YOUNG PLANTS OF PEQUIZEIRO

    Yvo de Carvalho

    2007-09-01

    Full Text Available

    Foram descritas as características de lesões e morfologia de colônias de <em>Pestalotia> <em>sp>., <em>Phomopsis spem>., <em>Stigmella spem>., <em>Chaetophoma sp.em>, <em>Helminthosporium sp.em> e <em>Epicoccum sp. em>obtidas de folhas de mudas de pequizeiro em viveiros nos municípios de Goiânia e Hidrolândia (GO. Respostas positivas para patogenicidade foram obtidas de todos os isolados, exceto para <em>Chaetophoma sp.em> que foram consideradas inconclusivas. Observou-se que lesões foliares foram importante fator de retardamento no crescimento das mudas.

    PALAVRAS-CHAVE: <em>Caryocar brasiliensisem>; pequizeiro; doenças foliares de pequizeiro; pequizeiro.

    Leaf lesions and morphological description of <em>Pestalotia sp.em>, <em>Phomopsis spem>., <em>Stigmella sp.em>, <em>Chaetophoma sp.em>, <em>Helminthosporium sp.em> and <em>Epicoccum sp.em> cultures obtained from young plants of pequizeiro (<em>Caryocar brasiliensis Camb.em> in nurseries in Goiânia and Hidrolândia counties. All the isolates except <em>Chaetophoma sp.em>, showed pathogenicity. Leaf spots greatly reduced plant growth.

    KEY-WORDS: Leaf diseases of pequizeiro.

  16. Aeromonas spp. IN PRODUCTS OF ANIMAL ORIGIN AND DRINKING WATER OF GOIÂNIA-GO Aeromonas spp. EM PRODUTOS DE ORIGEM ANIMAL E EM ÁGUA DE CONSUMO DE GOIÂNIA - GO

    Albenones José de Mesquita

    2007-09-01

    Full Text Available

    A total of 53 samples of products from animal origin and drinking water was examined for the presence of <em>Aeromonas spp.em> <em>Aeromonas> occurred in 26.41% (14/53 of the samples. The raw products showed high frequency of contamination and relatively high count Aeromonas hydrophila was the dominating species, 57.5%, being followed of <em>A. veroniem> (22.5%, <em>A. sobriaem> (17.5% and <em>A. mediaem> (2.5%. None of the <em>Aeromonas sppem>. was isolated from chlorinated or unchlorinated drinking water.

    KEY-WORDS: <em>Aeromonas>; animal origin products; drinking water.

    Um total de 53 amostras de produtos de origem animal e água de consumo foi examinado para se verificar a presença de <em>Aeromonas> <em>spp>. Desse total, 14/53 (26,41% amostras foram positivas para <em>Aeromonas>. Os produtos crus apresentaram maior freqüência de contaminação e contagem relativamente elevadas. A espécie <em>Aeromonas> <em>hydrophila> foi a mais freqüente (57,5%, seguida pelas espécies <em>A. veroniem> (22,5%, <em>A. sobriaem> (17,5% e A. media (2,5%. Nenhuma amostra de água de consumo, clorada ou não clorada, mostrou-se positiva para <em>Aeromonas> <em>ssp>.

    PALAVRA-CHAVE: <em>Aeromonas>; produtos de origem animal; água de consumo.

  17. Screening Commercially Available Entomopathogenic Biocontrol Agents for the Control of <em>Aethina tumidaem> (Coleoptera: Nitidulidae in the UK

    Giles E. Budge

    2012-08-01

    Full Text Available The Small hive beetle, <em>Aethina tumidaem>, is an invasive pest of honey bees. Indigenous to sub-Saharan Africa, it has now become established in North America and Australia. It represents a serious threat to European honey bees. Commercially available entomopathogenic agents were screened for their potential to control beetle larvae. Entomopathogenic fungi investigated had minimal impact. The nematodes <em>Steinernema> krausseiem> and <em>S. carpocapsaeem> provided excellent control with 100% mortality of larvae being obtained. Sequential applications of the nematodes following larvae entering sand to pupate also provided excellent control for up to 3 weeks. The information gained supports the development of contingency plans to deal with <em>A. tumidaem> should it occur in the UK, and is relevant to the management of Small hive beetle where it is already present.

  18. Salmonelose humana e animal em Araraquara, S. Paulo: prevalência de Shigella em casos humanos

    Deise Pasetto Falcão

    1975-10-01

    Full Text Available Admitida uma baixa freqüência de Salmonella com base em verificações anteriores em casos de diarréia aguda na cidade de Araraquara, S. Paulo, realizou-se uma investigação com um esquema ampliado para o isolamento de Salmonella a partir de 47 casos de gastroenterite infantil, 51 amostras de fezes de animais e 50 amostras de carnes e vísceras de animais destinados a alimentação. Foram isoladas Salmonella em 6,3% dos casos de gastroenterite, 5,8% de fezes de animais e 8,0% de amostras de alimentos, nesse último caso verificando-se a contaminação exclusivamente em fígado de porco, senão negativos todos os resultados de carne e vísceras de bovinos. Os sorotipos isolados corresponderam, em ordem decrescente de freqüência a S. anatum, S. derby e S. daytona. Nas gastroenterites infantis a freqüência de Shigella (12,7% foi duas vezes superior à de Salmonella (6,3%.

  19. Prevalência de transtornos mentais comuns em trabalhadores de enfermagem em um hospital da Bahia

    Eder Pereira Rodrigues

    2014-04-01

    Full Text Available Neste estudo, objetivou-se descrever a prevalência de "suspeitos" de transtornos mentais comuns (TMC em trabalhadores de enfermagem em um hospital geral, no estado da Bahia. Realizou-se um estudo epidemiológico, de corte transversal, com 309 profissionais de enfermagem, que trabalhavam em atividades assistenciais em um hospital de grande porte. Os profissionais de enfermagem referiram sobrecarga de trabalho e baixa remuneração. As queixas de saúde mais frequentes estavam relacionadas à postura corporal e a saúde mental. A prevalência geral de "suspeitos" de TMC foi de 35,0%. Em relação aos aspectos psicossociais do trabalho, relataram uma alta demanda psicológica e baixo controle sobre as atividades laborais. Os resultados obtidos apontam que as condições de trabalho e saúde observadas, não são adequadas para a efetiva realização do trabalho de enfermagem no hospital estudado.

  20. Os Códigos QR em museus

    Costa, Rui Pedro de Oliveira Reis da

    2012-01-01

    Mestrado em Museologia: Conteúdos Expositivos O estudo realizado na presente dissertação consiste em desenvolver uma planificação de medidas e técnicas, que permite aos técnicos de museu realizarem uma implementação, de uma forma simples, acessível e gratuita dos Códigos QR (Quick Response). O Código QR é um código bidimensional capaz de armazenar mais informação que um código de barras, sendo possível a sua descodificação através de uma aplicação instalada num smartphone. As análise...

  1. Lufenuron no tratamento da dermatofitose em gatos?

    Regina R. Ramadinha; Romeika K. Reis; Sergio G. Campos; Sabrina S. Ribeiro; Paulo V. Peixoto

    2010-01-01

    Em função de controvérsias sobre a eficácia do lufenuron no tratamento da dermatofitose causada por Microsporum canis, o efeito da droga foi avaliado em 46 gatos (30 com lesões cutâneas e 16 portadores assintomáticos) atendidos no Hospital Veterinário da Universidade Federal Rural do Rio de Janeiro, Brasil. O diagnóstico foi estabelecido através da lâmpada de Wood, da cultura fúngica e, adicionalmente, na maioria dos animais sintomáticos, pela avaliação histopatológica da pele. Os animais for...

  2. Influence of Chemical Extraction Conditions on the Physicochemical and Functional Properties of Polysaccharide Gum from Durian (<em>Durio> <em>zibethinus> Seed

    Bahareh Tabatabaee Amid

    2012-05-01

    Full Text Available Durian seed is an agricultural biomass waste of durian fruit. It can be a natural plant source of non-starch polysaccharide gum with potential functional properties. The main goal of the present study was to investigate the effect of chemical extraction variables (<em>i.e>., the decolouring time, soaking temperature and soaking time on the physicochemical properties of durian seed gum. The physicochemical and functional properties of chemically-extracted durian seed gum were assessed by determining the particle size and distribution, solubility and the water- and oil-holding capacity (WHC and OHC. The present work revealed that the soaking time should be considered as the most critical extraction variable affecting the physicochemical properties of crude durian seed gum.

  3. COMPETÊNCIAS INFORMACIONAIS EM TURISMO

    Fabrício Peixoto Vasconcelos

    2012-01-01

    Full Text Available Este artigo tem como objetivo analisar as competências informacionais relacionadas à prática de Turismo no Brasil. Fundamenta-se em um referencial teórico construído a partir de um diálogo interdisciplinar entre o Turismo e outras áreas do conhecimento, tais como: Ciências da Informação, Educação e áreas afins utilizadas. A construção textual teve como estratégia metodológica a pesquisa bibliográfica, on-line e documental, priorizando a análise descritiva documental. Conclui com a compreensão de que este artigo se reverte sobremaneira em referência para estudos acerca da relação entre competências e modalidades de Turismo na contemporaneidade, tomando como base a perspectiva informacional do profissional.

  4. O conceito de lei em Hannah Arendt

    Sônia Maria Schio

    2012-12-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2012v11n3p289Hannah Arendt (1906-1975 embora não tenha sistematizado uma Teoria ou Filosofia do Direito escreveu, em várias obras, apontamentos acerca dos Direitos Humanos e sobre a lei. E é nesse sentido que se pode perguntar: qual é a concepção de lei em Arendt? Na hipótese a ser desenvolvida, Arendt parte de uma crítica às Declarações de Direitos Humanos, pensando a lei por um viés republicano, ligado à política e ao cidadão participante e responsável.

  5. Espaço Público em Habermas

    Silva, Filipe Carreira da

    2002-01-01

    Neste livro, em que se sublinha a importância da história das ideias para a teoria em ciências sociais, Filipe Carreira da Silva analisa a evolução da noção de espaço público na obra de Jürgen Habermas, desde A Mudança Estrutural da Esfera Pública (1962) até ao recente Entre Factos e Normas (1992). A principal conclusão deste estudo aponta para uma notável continuidade na forma como Habermas conceptualiza aquela noção, não obstante a clara evolução das suas posições ao longo de quase quarenta...

  6. Listeria monocytogenes em alimentos prontos para consumo

    Castro, José Luís Draper Mineiro Romano de

    2011-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária Nota introdutória - Bactéria matou 13 em 22 meses Um surto de Listeriose que se regista na região de Setúbal e Almada há 22 meses, desde Janeiro de 2009, já afectou, pelo menos, 24 pessoas, 13 das quais morreram. O CM apurou que uma grávida perdeu o filho na 32ª semana de gestação após comer alimentos infectados com a bactéria Listeria. As vítimas mortais foram idosos e pessoas imunodeprimidas (com o sistema imunit...

  7. Rapsódia em agosto

    Sergio Leitão

    2015-08-01

    Full Text Available Neste artigo analiso se a tragédia das explosões nucleares em Hiroshima e Nagasaki ensinou algo de definitivo à humanidade, demonstrando o poder fatal das armas nucleares, o que continuaria a justificar o seu banimento da face da Terra. E o faço debatendo em que medida as discussões sobre o poder atômico repercutiram no Brasil, apontando as similaridades entre os argumentos utilizados nos idos dos anos 1970 e no momento atual, quando setores do país argumentam que não podemos prescindir do poderio atômico para assegurar nossa devida relevância no cenário político internacional.

  8. Alterações posturais em futebolistas

    Forte, Pedro Miguel Gomes

    2014-01-01

    Objetivo: Este estudo teve como objetivo, analisar a prevalência dos desvios posturais e a relação que possa existir com o nível competitivo e escalão etário, tipo de coordenação dominante, posicionamento em campo, maturação sexual, níveis de força e flexibilidade em jovens futebolistas. Métodos: A amostra, deste estudo transversal, foi constituída por 47 sujeitos do sexo masculino, com idades entre os 9 e 16 (13.02 + 2.51) anos. Para a avaliação postural foi utilizado o softwa...

  9. Formas farmacêuticas em pediatria

    Valente, Sara Carolina Cachado Gomes Jacinto

    2014-01-01

    Dissertação de mestrado, Ciências Farmacêuticas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2014 Em 2010, cerca de 21% da população europeia era constituída por crianças: uma percentagem correspondente a mais de 100 milhões de pessoas. As crianças representam um grupo da população vulnerável, com diferenças de desenvolvimento, fisiológicas e psicológicas em relação aos adultos. Não são meros “adultos pequenos”. A investigação relacionada com a idade e com o desenvolviment...

  10. Conhecer os utilizadores de Homebanking em Portugal

    Negas, Mário Carrilho; Lopes, José Martinho

    2012-01-01

    O artigo tem como objetivo caracterizar os utilizadores dos serviços de homebanking em Portugal, e identificar quais as operações bancárias mais realizadas no âmbito do serviço de homebanking. A análise da população portuguesa quanto à utilização dos meios eletrónicos bancários divide-a em três grupos distintos: os utilizadores da banca tradicional, que apenas se relacionam com o seu banco deslocando-se à agência física; os utilizadores da primeira geração de canais eletrónicos, como as Caixa...

  11. Produção de matéria seca, crescimento radicular e absorção de cálcio, fósforo e alumínio por coffea canephora e coffea arabica sob influência da atividade do alumínio em solução Dry matter production, root growth and calcium, phosphorus and aluminum absorption by coffea canephora and coffea arabica under influence of aluminum activity in solution

    Edson Marcio Mattiello; Marcos Gervasio Pereira; Everaldo Zonta; Jocimar Mauri; José Dioenis Matiello; Paulo Geovane Meireles; Ivo Ribeiro da Silva

    2008-01-01

    Este trabalho teve como objetivo avaliar a produção de matéria seca, o crescimento radicular e a absorção e distribuição do Ca, P e Al nas folhas, no caule e nas raízes de dois clones de café conilon (Coffea canephora) (Mtl 25 e Mtl 27) e de uma variedade de café Catuaí Amarelo (Coffea arabica), cultivados em solução nutritiva com atividade crescente de Al3+. As plantas foram cultivadas em vasos com capacidade para 5 L, contendo solução nutritiva de Hoagland & Arnon, modificada. Após oito dia...

  12. Imunoistoquímica em oligodendrogliomas

    Hilbig Arlete

    2006-01-01

    Full Text Available Os oligodendrogliomas (OL são tumores gliais caracterizados histologicamente pela presença de núcleo redondo e homogêneo com halo claro perinuclear. A diferenciação microscópica desses tumores com neurocitoma central, DNT e algumas vezes com ependimoma de células claras pode ser difícil. O estudo imunoistoquímico com marcadores glial e neuronal tem sido utilizado e pode auxiliar no diagnóstico diferencial. O objetivo do presente estudo foi determinar a diferenciação neuronal e glial por meio de técnica imunoistoquímica utilizando anticorpos de rotina em tumores com características microscópicas de OL. Foram estudados 42 pacientes com idade entre 4 e 60 anos. Dez apresentavam sinais de maior malignidade (anaplásico. Trinta e três casos (78,5% mostraram positividade para GFAP, sendo em 10 focal e 6 casos com expressão intensa. Doze casos (28,5% apresentaram positividade para NSE e/ou sinaptofisina, demonstrando alguma diferenciação neuronal, principalmente focal. Trinta e quatro casos (80,9% foram positivos para S-100 e três casos (7,1% foram positivos focalmente para NeuN. Concluimos que áreas focais de diferenciação neuronal e/ou glial podem estar presente em OL típicos e, portanto, é necessário cautela no diagnóstico diferencial em amostras pequenas de tumor. A positividade difusa para marcadores neuronais deve sugerir o diagnóstico de neurocitoma central.

  13. Subsurface imaging by electrical and EM methods

    NONE

    1998-12-01

    This report consists of 3 subjects. 1) Three dimensional inversion of resistivity data with topography : In this study, we developed a 3-D inversion method based on the finite element calculation of model responses, which can effectively accommodate the irregular topography. In solving the inverse problem, the iterative least-squares approach comprising the smoothness-constraints was taken along with the reciprocity approach in the calculation of Jacobian. Furthermore the Active Constraint Balancing, which has been recently developed by ourselves to enhance the resolving power of the inverse problem, was also employed. Since our new algorithm accounts for the topography in the inversion step, topography correction is not necessary as a preliminary processing and we can expect a more accurate image of the earth. 2) Electromagnetic responses due to a source in the borehole : The effects of borehole fluid and casing on the borehole EM responses should thoroughly be analyzed since they may affect the resultant image of the earth. In this study, we developed an accurate algorithm for calculating the EM responses containing the effects of borehole fluid and casing when a current-carrying ring is located on the borehole axis. An analytic expression for primary vertical magnetic field along the borehole axis was first formulated and the fast Fourier transform is to be applied to get the EM fields at any location in whole space. 3) High frequency electromagnetic impedance survey : At high frequencies the EM impedance becomes a function of the angle of incidence or the horizontal wavenumber, so the electrical properties cannot be readily extracted without first eliminating the effect of horizontal wavenumber on the impedance. For this purpose, this paper considers two independent methods for accurately determining the horizontal wavenumber, which in turn is used to correct the impedance data. The 'apparent' electrical properties derived from the corrected impedance

  14. Nd:Yag laser em catarata infantil

    Di Giovanni Maria Elizabeth

    2006-01-01

    Full Text Available OBJETIVO: Descrever e avaliar a utilização do Nd:Yag laser em crianças pseudofácicas. MÉTODOS: Foram estudados prospectivamente 24 olhos de 22 pacientes pseudofácicos no Serviço de Catarata Congênita da Universidade Federal de São Paulo/Escola Paulista de Medicina, no período de junho de 2001 a março de 2003, com opacidade da cápsula posterior, submetidos à capsulotomia posterior com Nd:Yag laser. Analisamos a idade na cirurgia, tipo de cirurgia, tipo e localização da lente intra-ocular, tempo entre a cirurgia e a opacidade capsular posterior, o número de sessões, energia utilizada, lateralidade, acuidade visual pré e pós- Nd:Yag laser. RESULTADOS: Todos os 24 olhos pseudofácicos foram submetidos a capsulotomia posterior com Nd:Yag laser. Destes, quatro (16,6% apresentavam lente intra-ocular acrílica e 18 (75% de PMMA. Sendo 12 LIOs no saco capsular e nove no sulco ciliar. A energia utilizada foi de 0,8mJ a 2mJ por disparo, total de 100mJ por sessão. A utilização do Nd:Yag laser mostrou-se viável em 22 (91,6% olhos. Em dois (8,3% olhos houve necessidade de capsulotomia cirúrgica. CONCLUSÃO: Os resultados obtidos sugerem que a capsulotomia com Nd:Yag laser possa ser boa opção para a obtenção da transparência do eixo visual e melhora da qualidade visual em crianças pseudofácicas.

  15. FINANCIAL AND TECHNICAL ASPECTS OF EMS AUDIT

    Emil HOROMNEA; Florian Marcel NUTA

    2007-01-01

    The main purpose of this paper is to discuss the problem of auditing the environmental pressures and impacts and to clarify the advantages of this process. We discuss about the connections between the audit financial and technical aspects and the main standards. ISO 14001 defines environmental audit by the systematical and documented process of assessment. The EMS as an environmental performance tool is the key for the continuous improvement of the environmental impact. The audit process part...

  16. Molecular Identification of Chronic Bee Paralysis Virus Infection in <em>Apis melliferaem> Colonies in Japan

    Tomomi Morimoto

    2012-06-01

    Full Text Available Chronic bee paralysis virus (CBPV infection causes chronic paralysis and loss of workers in honey bee colonies around the world. Although CBPV shows a worldwide distribution, it had not been molecularly detected in Japan. Our investigation of <em>Apis melliferaem> and <em>Apis cerana japonicaem> colonies with RT-PCR has revealed CBPV infection in <em>A. melliferaem> but not <em>A. c. japonicaem> colonies in Japan. The prevalence of CBPV is low compared with that of other viruses: deformed wing virus (DWV, black queen cell virus (BQCV, Israel acute paralysis virus (IAPV, and sac brood virus (SBV, previously reported in Japan. Because of its low prevalence (5.6% in <em>A. melliferaem> colonies, the incidence of colony losses by CBPV infection must be sporadic in Japan. The presence of the (− strand RNA in dying workers suggests that CBPV infection and replication may contribute to their symptoms. Phylogenetic analysis demonstrates a geographic separation of Japanese isolates from European, Uruguayan, and mainland US isolates. The lack of major exchange of honey bees between Europe/mainland US and Japan for the recent 26 years (1985–2010 may have resulted in the geographic separation of Japanese CBPV isolates.

  17. Protective Effect of <em>T. violaceaem> Rhizome Extract Against Hypercholesterolemia-Induced Oxidative Stress in Wistar Rats

    Olorunnisola Sinbad Olorunnisola

    2012-05-01

    Full Text Available The present study examines the effect of methanolic extract of <em>T. violaceaem> rhizomes on high cholesterol (2% diet fed rats (HCD. At the end of 4 weeks, serum total protein, albumin, reduced glutathione (GSH, and markers of oxidative stress viz., catalase (CAT, superoxide dismutase (SOD, thiobarbituric acid reactive substances (TBARS—a marker of lipid peroxidation, glutathione-S-transferase (GST and glutathione peroxidase (GPx in the serum, aorta, liver and heart of HCD and normal rats were assessed and compared. A significant (<em>p> < 0.05 elevation in TBARS, and a reduction (<em>p> < 0.05 in serum total protein, albumin, GSH and antioxidant enzyme activities was observed in tissues of HCD fed rats compared with the normal group. Co-administration of crude extracts of <em>T. violaceaem> rhizomes protected the liver, heart, serum and aorta against HCD-induced lipid peroxidation in a dose dependant manner. The activities of the extract (500 mg/kg compared favorably with gemfibrozil. The extracts also protected against HCD-induced reduction in serum total protein, GSH and restored the activities of antioxidant tissues (liver, heart and aorta enzymes to near normal values. This result suggested that consumption of <em>T. violaceaem> rhizome may help to protect against hypercholesterolemia- induced oxidative stress diseases in the heart and liver.

  18. Antioxidative Characteristics of <em>Anisomeles indicaem> Extract and Inhibitory Effect of Ovatodiolide on Melanogenesis

    Li-Ling Chang

    2012-05-01

    Full Text Available The purpose of the study was to investigate the antioxidant characteristics of <em>Anisomeles indicaem> methanol extract and the inhibitory effect of ovatodiolide on melanogenesis. In the study, the antioxidant capacities of <em>A. indicaem> methanol extract such as DPPH assay, ABTS radical scavenging assay, reducing capacity and metal ion chelating capacity as well as total phenolic content of the extract were investigated. In addition, the inhibitory effects of ovatodiolide on mushroom tyrosinase, B16F10 intracellular tyrosinase and melanin content were determined spectrophotometrically. Our results revealed that the antioxidant capacities of <em>A. indicaem> methanol extract increased in a dose-dependent pattern. The purified ovatodiolide inhibited mushroom tyrosinase activity (IC50 = 0.253 mM, the compound also effectively suppressed intracellular tyrosinase activity (IC50 = 0.469 mM and decreased the amount of melanin (IC50 = 0.435 mM in a dose-dependent manner in B16F10 cells. Our results concluded that <em>A. indicaem> methanol extract displays antioxidant capacities and ovatodiolide purified from the extract inhibited melanogenesis in B16F10 cells. Hence, <em>A. indicaem> methanol extract and ovatodiolide could be applied as a type of dermatological whitening agent in skin care products.

  19. Surveying for the rare Bechstein’s bat (<em>Myotis bechsteiniiem> in northern Iberian peninsula by means of an acoustic lure

    Urtzi Goiti

    2008-02-01

    Full Text Available Abstract In the Araba province (Basque Country, Iberian Peninsula we surveyed for the rare Bechstein’s bat (<em>Myotis bechsteiniiem> using a recently developed method based on an acoustic lure, the Sussex AutoBat. We surveyed 16 deciduous woodlands, an irrigation pool and a cave, a total of 45 sites. The synthesized calls were played behind mist nets following an established protocol. In total, we captured 32 bats representing 6 genera and 10 species; among these, 6 <em>M. bechsteiniiem>, 3 <em>M. daubentoniiem>, 4 <em>Nyctalus leisleriem>, 5 <em>Plecotus auritusem>, 1 <em>P. austriacusem>, and 1 <em>Barbastella barbastellusem> were caught using the acoustic lure. Two of the Bechstein’s bats were lactating females. By radiotracking one of them, we found the third known breeding colony for this rare species in the Iberian Peninsula. The acoustic lure proved to be a promising method for improving the trapping success of this species. Riassunto Indagine sul Vespertilio di Bechstein (<em>Myotis bechsteiniiem> in Spagna mediante emissioni sonore. Il monitoraggio del Vespertilio di Bechstein (<em>Myotis bechsteiniiem>, specie rara di chirottero nella provincia di Araba (Paesi Baschi, penisola iberica, è stato effettuato mediante l’utilizzo di emissioni ultrasonore per attrarre gli animali (Sussex AutoBat. Sono stati monitorati 45 siti, distribuiti in 16 differenti boschi a latifoglie, un bacino utilizzato per scopi irrigui e una grotta. In ciascun sito sono state utilizzate reti mist net di varia lunghezza e sono stati emessi richiami ultrasonori in prossimità delle reti stesse, secondo una procedura standardizzata. In totale, grazie all'utilizzo delle emissioni sonore sono stati caturati 32 pipistrelli appartenenti a 10 specie, tra cui 6 <em>M. bechsteiniiem>, 3 <em>M. daubentoniiem>, 4 <em>Nyctalus leisleriem>, 5 <em>Plecotus auritusem>, 1 <em>P. austriacusem

  20. Phenolics and Flavonoids Compounds, Phenylanine Ammonia Lyase and Antioxidant Activity Responses to Elevated CO2 in <em>Labisia pumilaem> (Myrisinaceae

    Hawa Z.E. Jaafar

    2012-05-01

    Full Text Available A split plot 3 × 3 experiment was designed to examine the impact of three concentrations of CO2 (400, 800 and 1,200 µmol·mol−1 on the phenolic and flavonoid compound profiles, phenylalanine ammonia lyase (PAL and antioxidant activity in three varieties of <em>Labisia pumilaem> Benth. (var. <em>alata,> pumila em>and> lanceolataem> after 15 weeks of exposure. HPLC analysis revealed a strong influence of increased CO2 concentration on the modification of phenolic and flavonoid profiles, whose intensity depended on the interaction between CO2 levels and <em>L. pumilaem> varieties. Gallic acid and quercetin were the most abundant phenolics and flavonoids commonly present in all the varieties. With elevated CO2 (1,200 µmol·mol−1 exposure, gallic acid increased tremendously, especially in var. <em>alata> and <em>pumila em>(101–111%, whilst a large quercetin increase was noted in var. <em>lanceolata> (260%, followed closely by <em>alata> (201%. Kaempferol, although detected under ambient CO2 conditions, was undetected in all varieties after exposure. Instead, caffeic acid was enhanced tremendously in var. <em>alata> (338~1,100% and <em>pumila em>(298~433%. Meanwhile, pyragallol and rutin were only seen in var. <em>alata> (810 µg·g−1 DW and <em>pumila> (25 µg·g−1 DW, respectively, under ambient conditions; but the former compound went undetected in all varieties while rutin continued to increase by 262% after CO2 enrichment. Interestingly, naringenin that was present in all varieties under ambient conditions went undetected under enrichment, except for var. <em>pumila em>where it was enhanced by 1,100%. PAL activity, DPPH and FRAP also increased with increasing CO2 levels implying the possible improvement of health-promoting quality of Malaysian <em>L. pumilaem

  1. Agrupando amostras que diferem alometricamente em tamanho

    William D. Ross

    1997-12-01

    Full Text Available Um introdução ilustrada à teoria dimensional é utilizada para enfocar a questão do agrupamento de amostras que diferem alometricamente em tamanho. Nenhuma das idéias foram originadas pelo autor. Na realidade, os princípios são bem conhecidos. Os proponentes do índice de massa corporal que utilizam uma escala comum para indivíduos entre 20 e 65 anos de idade os ignoram escandalosamente. O erro ao agrupar amostras é demonstrado utilizando-se regressões log-log do peso em relação ao preditor altura para homens, mulheres e amostras combinadas de homens e mulheres em incrementos de 5 anos de 20 a 65 anos de idade. Este artigo serve como um convite para examinar a premissa da constância biológica ilustrada pelo tão conhecido índice de massa corporal, que nunca foi verdadeiro e, agora na era do microcomputador, é desnecesário.

  2. Resultados da microcirurgia em 54 aneurismas intracranianos

    Paulo Niemeyer

    1974-09-01

    Full Text Available O autor apresenta sua experiência em 54 aneurismas arteriais intracranianos operados com técnica microcirúrgica, no período de janeiro de 1971 a março de 1974. Em 40 doentes classificados nos grupos I, II e III, não houve mortalidade. Incluindo 8 doentes do grupo IV, onde ocorreram 3 óbitos, a mortalidade foi de 6,2%. Nos doentes do grupo V, a mortalidade continua proibitiva, seja qual for a técnica usada. Os doentes foram operados com microscópio cirúrgico de fabricação brasileira, sendo usados clips de Yasargil, Scoville, Mayfield e de modelo do autor. Comparando os resultados atuais de microcirurgia (1971-1974, com a experiência anterior, baseada em cerca de 400 casos, no período de 1949 a 1970, o autor conclui que a cirurgia dos aneurismas com auxílio do microscópio é benigna e sem mortalidade nos doentes de bom risco cirúrgico. Considera a existência de espasmo o maior problema e julga que o momento mais oportuno de operar é quando surgem as melhoras clínicas, coincidindo com o desaparecimento do espasmo, entre o 7º e 10º dia, geralmente.

  3. Helicopter EMS: Research Endpoints and Potential Benefits

    Stephen H. Thomas

    2012-01-01

    Full Text Available Patients, EMS systems, and healthcare regions benefit from Helicopter EMS (HEMS utilization. This article discusses these benefits in terms of specific endpoints utilized in research projects. The endpoint of interest, be it primary, secondary, or surrogate, is important to understand in the deployment of HEMS resources or in planning further HEMS outcomes research. The most important outcomes are those which show potential benefits to the patients, such as functional survival, pain relief, and earlier ALS care. Case reports are also important “outcomes” publications. The benefits of HEMS in the rural setting is the ability to provide timely access to Level I or Level II trauma centers and in nontrauma, interfacility transport of cardiac, stroke, and even sepsis patients. Many HEMS crews have pharmacologic and procedural capabilities that bring a different level of care to a trauma scene or small referring hospital, especially in the rural setting. Regional healthcare and EMS system's benefit from HEMS by their capability to extend the advanced level of care throughout a region, provide a “backup” for areas with limited ALS coverage, minimize transport times, make available direct transport to specialized centers, and offer flexibility of transport in overloaded hospital systems.

  4. Adaptabilidade e estabilidade em aveia em ambientes estratificados Adaptability and stability in oat in stratified environments

    Giovani Benin; Fernando Irajá Félix de Carvalho; Antônio Costa de Oliveira; Claudir Lorencetti; Eduardo Alano Vieira; Jefferson Luís Meireles Coimbra; Igor Pires Valério; Elmar Luíz Floss; Ivandro Bertan; Giovani Olegário da Silva

    2005-01-01

    Vinte cultivares de aveia (Avena sativa L.) foram avaliados para rendimento de grãos nas safras agrícolas de 2001 e 2002 em nove locais dos estados do Paraná, Rio Grande do Sul e São Paulo, com o objetivo de avaliar as estimativas dos componentes de adaptabilidade e estabilidade do rendimento de grãos em ambientes favoráveis e desfavoráveis em presença e ausência de aplicação de fungicida. Foi empregada a metodologia de EBERHART & RUSSELL (1966). A presença de significância para anos, genótip...

  5. A gente se liga em voc: reconfiguraes da TV Globo em um cenrio de convergncia miditica

    Diego Gouveia Moreira

    2012-06-01

    Full Text Available Os 46 anos da Rede Globo foram comemorados com o lanamento de uma nova assinatura. Em vez do a gente se v por aqui, a emissora passou a usar a gente se liga em voc. O novo slogan volta a ateno para o telespectador. Entender o processo de transio da TV em um cenrio de convergncia e as adaptaes que a TV Globo tem implementado para atender s novas demandas so os principais objetivos deste artigo. Para isso, so abordadas as mudanas que os meios tradicionais esto realizando diante dos novos meios e so mostradas as principais estratgias da Globo nesse ecossistema miditico. Por fim, o artigo constata a instaurao de um novo estatuto da televiso.

  6. Determinação de hemogregarina em Boa constrictor constrictor mantidos em cativeiro

    Monique A. Luz; Andre M.C. Meneses; Carla C.G. de Moraes; Larissa dos S. Seixas; Dennis J. da S. Lima; Luis A.A. dos S. Ruffeil; Paulo H.G. de Castro; Antonio M. Costa

    2012-01-01

    O presente estudo teve como objetivo determinar a presença de hemogregarina em boídeos mantidos em cativeiro no Estado do Pará, bem como, relacionar a hemoparasitose com pre-disposição sexual, alterações clínicas e hematológicas e a presença de ectoparasitos. Esta pesquisa teve autorização do Sistema de Autorização e Informação em Biodiversidade do Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais Renováveis para ser realizado. Utilizaram-se 19 serpentes da família Boidae mantidas...

  7. Sintesi sulla morfometria del primo molare inferiore nel gruppo <em>Microtus (Terricola saviiem>

    Armando Nappi

    2003-10-01

    Full Text Available <em>Microtus (Terricola saviiem> è distribuito su quasi tutta la penisola italiana e la Sicilia. La sottospecie <em>brachycercus>, descritta su esemplari della Sila (Calabria, risulta essere buona specie da studi cromosomici. È stata testata la morfometria del primo molare inferiore tramite 27 variabili considerando 55 (di cui 2 fossili popolazioni di <em>M. saviiem> (1351 denti e 7 di <em>Terricola> calabresi (221 denti. Se il numero di denti risultava basso si sono raggruppate più popolazioni quando possibile. Sugli assi dell?analisi discriminante è interessante notare come, benché vi siano somiglianze tra popolazioni che seguono una logica geografica, altre popolazioni vicine geograficamente risultano molto distanti dal punto di vista morfologico e somigliano per contro a popolazioni differenti sia per posizione geografica che situazioni ecologiche. È noto nelle arvicole il fenomeno per il quale una determinata specie, oltre ai morfotipi dentari ad essa tipici, ne possiede altri simili se non identici a quelli di altre specie (serie di Vavilov. Lo stesso fenomeno è osservabile a livello di popolazione nello studio da noi effettuato. Interessanti anche le posizioni marginali di alcune popolazioni come Lotrago di Romagnano (VR, Zelarino (VE, Valle Millecampi (VE, Nonantola (MO, Imola-Romitorio (BO/RA, Monti della Tolfa (RM, Torre del Greco (NA, Melissano (LE, Monteparano (TA, Fontasala (TP, Roccapalumba (PA. Considerando infine nell?insieme tutte le popolazioni di <em>savii> e <em>Terricola> calabresi, dall?analisi della varianza si riscontrano differenze significative in: lunghezza relativa della parte anteriore (p<0.0001; med 51.126 sav, 50.324 cal, inclinazione rombo pitimiano (p<0.0001; med -0.018 sav, ?0.043 cal, strozzatura cappio anteriore (p<0.0001; med 25.694 sav, 29.704 cal, V6/V21 (p<0.0001; med 2.582 sav, 2.509 cal, (V10-V9/V6 (p<0.0001; med 13.915 sav, 13.040 cal, (V12-V10/V6 (p<0.0001; med 2.180 sav, 2

  8. EM Clustering Analysis of Diabetes Patients Basic Diagnosis Index

    Wu, Cai; Steinbauer, Jeffrey R.; Kuo, Grace M

    2005-01-01

    Cluster analysis can group similar instances into same group. Partitioning cluster assigns classes to samples without known the classes in advance. Most common algorithms are K-means and Expectation Maximization (EM). EM clustering algorithm can find number of distributions of generating data and build “mixture models”. It identifies groups that are either overlapping or varying sizes and shapes. In this project, by using EM in Machine Learning Algorithm in JAVA (WEKA) syste...

  9. Is There an `EMS' Effect in European Labour Markets?

    Artis, Michael J; Ormerod, Paul

    1991-01-01

    It is claimed that membership of the exchange rate mechanism (ERM) of the European Monetary System (EMS) gives countries a credibility bonus which reduces the output and employment costs of disinflation. Within the EMS this arises because of the commitment of participants in the ERM to maintain their parities against the Deutschmark, with Germany acting as a low-inflation anchor. The paper finds evidence of such a credibility effect: during `the EMS period' (flexibly dated) German inflation e...

  10. Children recognize emotions of EmI companion robot

    Saint-Aimé, Sébastien; Le Pevedic, Brigitte; Duhaut, Dominique

    2011-01-01

    This article presents the evaluation of the emotional expressiveness of EmI companion robot in the EmotiRob project. We describe iGrace emotional computational model of emotion to generate an emotional response based on the speech of the interlocutor, the mechanical design and implementation of EmI, and experimentation to evaluate the expressiveness of EmI with 52 school children aged 7 to 9 years.

  11. O Estrangeiro – Um ensaio em Psicologia Social

    Alfred Schütz

    2010-01-01

    RESUMO: Este texto é uma tradução de um artigo de Alfred Schütz, <em style="mso-bidi-font-style: normal;">The Strangerem>: Na Essay in Social Psychology, publicado originalmente no <em style="mso-bidi-font-style: normal;">The Ameri...

  12. Aclimatização de mudas micropropagadas de bananeira 'Grand Naine' com aplicação de biofertilizantes em duas estações do ano

    Edson Shigueaki Nomura

    2012-08-01

    Full Text Available A utilização de mudas de bananeira micropropagadas de qualidade é o primeiro passo na implantação de um bom pomar e, para isso, sua aclimatização deve ser realizada de forma adequada. Em vista disso, objetivou-se, neste trabalho, avaliar o desempenho dos biofertilizantes HUMITEC® e RUTER AA® no desenvolvimento de mudas de bananeira micropropagadas, sendo instalado um experimento em viveiro comercial de produção de mudas. Foram utilizadas mudas de bananeira cv. Grand Naine, obtidas por micropropagação, sendo, posteriormente, transplantadas em sacos de polietileno preto (1,5 L, contendo, como substrato, terra de subsolo (Latossolo Amarelo, casca de arroz carbonizada e composto orgânico Organifol® (1:1:1. O delineamento experimental foi em blocos ao acaso, fatorial 2 x 4 (produtos e doses, com quatro repetições e quatro plantas úteis por parcela. Os tratamentos foram compostos pelos seguintes biofertilizantes e doses: HUMITEC® (0,0; 4,0; 8,0; 16,0 mL planta-1 e RUTER AA® (0,0; 2,0; 4,0; 8,0 mL planta-1. As doses dos produtos foram divididas em duas aplicações (28 e 56 dias após o transplantio das mudas, aplicadas via fertirrigação. Noventa e oito dias após o transplantio avaliaram-se as seguintes variáveis: altura das plantas (cm, diâmetro do colo rente superfície do solo (mm, área foliar total e por folha, biomassas fresca e seca da parte aérea e das raízes (g. Os dados foram submetidos análise da variância e quando o teste F foi significativo, realizou-se análise de regressão. Pode-se concluir que aplicações de HUMITEC® e RUTER AA® favoreceram o desenvolvimento das mudas e que, no verão, as plantas apresentaram maior desenvolvimento durante a aclimatização.

  13. Fenomenologia e fenomenismo em Husserl e Mach

    Denis Fisette

    2009-12-01

    Full Text Available Como conciliar as repetidas críticas ao fenomenismo de Mach, um pouco por toda a obra de Husserl, com o papel proeminente que Husserl parece nele reconhecer em seus últimos trabalhos, quanto à gênese de sua própria fenomenologia? Para responder a essa questão, examinaremos, primeiramente, a relação estreita que Husserl estabelece entre o método fenomenológico e o descritivismo de Mach à luz do debate que opõe nativismo e empirismo sobre a origem da percepção do espaço. Em seguida, examinaremos dois aspectos da crítica que Husserl faz ao positivismo de Mach: o primeiro se refere ao fenomenismo e sua doutrina dos elementos, enquanto o segundo, ao princípio de economia de pensamento, que Husserl associa a uma forma de psicologismo em Prolegômenos. A hipótese que nos guiará nesse estudo é que as opiniões aparentemente contraditórias de Husserl sobre o positivismo de Mach se explicam em parte pelo estatuto duplo que a fenomenologia recebe em seus últimos trabalhos: enquanto programa filosófico, ela se opõe explicitamente ao positivismo; enquanto método, ela se aparenta ao descritivismo de Mach. Concluiremos com a ideia de que esses dois filósofos de origem checa perseguiam o objetivo comum de apreender o sentido originário de positividade.How to conciliate the recurrent criticisms to Mach's phenomenism, a bit in all Husserl's work, with the outstanding role Husserl seems to recognise in phenomenism in his last works, as to the genesis of his own phenomenology? In order to answer this question, we examine, first, the close relationship stablished by Husserl between the phenomenological method and Mach's descriptivism in light of the debate that opposes nativism and empiricism regarding the origin of the perception of space. Next, we examine two features of Husserl's criticism to Mach's positivism: the first refers to phenomenism ans its doctrine of elements, and the second, to the principle of economy of thought, which

  14. Chemical Composition and <em>in Vitroem> Evaluation of the Antioxidant and Antimicrobial Activities of <em>Eucalyptus gillii em>Essential Oil and Extracts<em>>

    François Couderc

    2012-08-01

    Full Text Available In this study, essential oil and various extracts (hexane, petroleum ether, acetone, ethanol, methanol and water of <em>Eucalyptus giliiem> were screened for their chemical composition, antimicrobial and antioxidant activities. The essential oil chemical composition was analyzed by gas chromatography-mass spectrometry (GC-MS and gas chromatography-flame ionization detection (GC-FID, respectively. Thirty four compounds were identified, corresponding to 99.5% of the total essential oil. Tannins [104.9–251.3 g catechin equivalent (CE/Kg dry mass], flavonoids [3.3–34.3 g quercetin equivalent (QE/Kg dry mass], phenolics [4.7–216.6 g gallic acid equivalent (GAE/Kg dry mass] and anthocyannins [1.2–45.3 mg cyanidin-3-glucoside equivalent (C3GE/Kg dry mass] of various extracts were investigated. Free radical scavenging capacity of all samples was determinedt. In the 1,1-diphenyl-2-picrylhydrazyl (DPPH assay, the IC50 of essential oil was 163.5 ± 10.7 mg/L and in the 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonate (ABTS assay, it was 94.7 ± 7.1 mg/L. Among the various extracts, the water extract showed the best result (IC50 = 11.4 ± 0.6 mg/L in the DPPH assay which was comparable to vitamin C (IC50 = 4.4 ± 0.2 mg/L. The antimicrobial activities were evaluated against different bacterial and fungal strains. Gram positive bacteria were found to be more sensitive to the essential oil and extracts than Gram negative ones. Anthocyanins seem to have a major effect on the growth of <em>Bacillus subtilisem> (R2 = 0.79. A significant antifungal activity was observed against the yeast and fungi. Correlations between chemical composition and antioxidant activities were studied and R2 values were about 0.96 for the effect of phenolics on the DPPH assay.

  15. New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella junceaem>

    Tsong-Long Hwang

    2012-06-01

    Full Text Available Chemical investigation of <em>Junceella junceaem> has resulted in the isolation of three new briaranes designated juncenolides M–O (13. The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.

  16. Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral <em>Briareum excavatumem>

    Tsun-Tai Yeh

    2012-09-01

    Full Text Available In the continued search for novel bioactive substances from the Taiwanese octocoral <em>Briareum excavatumem> collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (13 were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NMR spectroscopic analysis and physical data. The anti-HCMV (human cytomegalovirus activity of 13 and their cytotoxicity against selected cancer cell lines were evaluated.

  17. Introduction to <em>Exporting American Dreams: Thurgood Marshall's African Journeyem>

    Dudziak, Mary L.

    2009-01-01

    Thurgood Marshall became a living icon of civil rights when he argued <em>Brown v. Board of Educationem> before the Supreme Court in 1954. Six years later, he was at a crossroads. A rising generation of activists were making sit-ins and demonstrations rather than lawsuits the hallmark of the civil rights movement. What role, he wondered, could he now play? When in 1960 Kenyan independence leaders asked him to help write their constitution, Marshall threw himself into th...

  18. Doenca renal policistica autossomica dominante em pacientes em hemodialise no sul do Brasil

    Everton Fernando Alves

    2014-03-01

    Full Text Available Introdução: A doença renal policística autossômica dominante é a enfermidade renal hereditária mais comum em seres humanos. Objetivo: Analisar a prevalência, características clínicas e laboratoriais de pacientes com rins policísticos e relacionar as manifestações da doença por gênero. Métodos: Trata-se de um estudo observacional e retrospectivo. Foram revisados todos os prontuários médicos de pacientes com rins policísticos admitidos para hemodiálise entre 1995 e 2012, em quatro centros que atendem a área de abrangência da 15ª regional de saúde do Paraná, Brasil. Resultados: Fizeram parte do estudo 48 pacientes com rins policísticos, causa primária da doença renal crônica (DRC estágio 5. A prevalência da doença foi de um em 10.912 habitantes. A média de idade de ingresso na hemodiálise (50,7 anos e o tempo de seguimento em hemodiálise até o transplante (36,5 meses foi menor nos homens. A hipertensão arterial foi o diagnóstico mais frequente em 73% dos pacientes, com predominância em mulheres (51,4%. O cisto hepático foi a manifestação extrarrenal mais frequente nos homens (60,0%. Foram a óbito 10,4% dos pacientes que faziam uso de hemodiálise, sendo 60% de homens. A classe de droga anti-hipertensiva mais utilizada foi a que atua no sistema renina-angiotensina, com maior frequência de uso nas mulheres (53,3%. A ureia pós-diálise foi significativamente maior em homens. Conclusão: A prevalência da doença é baixa entre pacientes em hemodiálise no sul do Brasil. As diferenças observadas entre os gêneros, com exceção da ureia pós, não foram significantes. Os dados encontrados são diferentes dos reportados na América do Norte e Europa.

  19. Revolvimento Ocasional e Calagem em Latossolo Muito Argiloso em Sistema Plantio Direto Consolidado

    Jonez Fidalski; Renato Yagi; Cássio Antonio Tormena

    2015-01-01

    RESUMO A ocorrência de concentração de nutrientes e compactação superficial tem sido relatada após longo tempo de implantação do sistema plantio direto. O objetivo deste estudo foi avaliar os atributos químicos, a densidade do solo e a produtividade das culturas subsequentes a uma única intervenção mecânica complementada com calagem de um Latossolo Vermelho Distroférrico textura muito argilosa conduzido em sistema plantio direto há 17 anos ininterruptos, em Pato Branco, no sudoeste do Paraná....

  20. Democracia e Autoritarismo em Honduras: o que está em jogo?

    CARLOS FEDERICO DOMÍNGUEZ AVILA

    2009-09-01

    Full Text Available O artigo trata da crise política em Honduras
    após o golpe de Estado de junho último. Argumentase
    que a melhor alternativa para resolver democraticamente
    a crise é o denominado acordo de São José.
    A posição brasileira, especialmente após a concessão
    de apóio e proteção ao presidente José Manuel Zelaya
    na embaixada em Tegucigalpa, é decisiva.

  1. Democracia e Autoritarismo em Honduras: o que está em jogo?

    CARLOS FEDERICO DOMÍNGUEZ AVILA

    2009-01-01

    O artigo trata da crise política em Honduras
    após o golpe de Estado de junho último. Argumentase
    que a melhor alternativa para resolver democraticamente
    a crise é o denominado acordo de São José.
    A posição brasileira, especialmente após a concessão
    de apóio e proteção ao presidente José Manuel Zelaya
    na embaixada em Tegucigalpa, é decisiva.

  2. Compostos antioxidantes em frutos de acessos de caramboleira em diferentes ambientes de Pernambuco

    José Severino de Lira Júnior; João Emmanoel Fernandes Bezerra; Ildo Eliezer Lederman; Lídia Cristina dos Santos Alencar Correia; Maria Inês Sucupira Maciel

    2014-01-01

    A polpa da carambola contém compostos químicos com propriedades antioxidantes importantes à saúde humana, contra o envelhecimento celular e a prevenção de doenças. Este trabalho objetivou avaliar o fruto de acessos de caramboleira quanto às concentrações de compostos antioxidantes. Foram analisadas as concentrações de ácido ascórbico, carotenoides totais, flavonoides, fenólicos totais e taninos em cinco acessos selecionados de carambola, cultivada em três distintas regiões edafoclimáticas de ...

  3. Controle alternativo da antracnose em fruto de goiabeira, em laboratório

    Rozwalka, Luciane Cristina

    2003-01-01

    Resumo: A antracnose ou mancha-chocolate é considerada uma das doenças mais graves em póscolheita na cultura da goiabeira (Psidium guajava L.), podendo vir a ser juntamente com o resíduo de produtos químicos um entrave para exportação. Embora, o controle químico de doenças de plantas, seja considerado em muitos casos, a única medida eficiente e economicamente viável de garantir produtividade e qualidade visadas pela agricultura moderna, o uso contínuo pode promover a seleção de fungos patogên...

  4. Estado nutritivo azotado e teor de nitratos em vegetais cultivados em agricultura urbana

    Rodrigues, M.A. (Manuel Augusto); Ferreira, I.Q.; Arrobas, Margarida

    2013-01-01

    O Instituto Politécnico de Bragança (IPB) iniciou um projeto de horticultura urbana em 2011 para proporcionar o convívio e atividade de lazer a sua comunidade académica. É, por principio, um projeto de agricultura orgânica, sendo os horticultores estimulados a usar praticas ambientalmente sustentáveis, evitando o uso de fertilizantes e pesticidas de síntese Industrial. Para facilitar a adoção de praticas consentâneas, o IPB disponibiliza estrume de vaca de forma gratuita e em quantid...

  5. Teores de carboidratos em estacas lenhosas de mirtileiro

    Rérinton Joabél Pires de Oliveira; Valmor João Bianchi; Rogério Ferreira Aires; Ângela Diniz Campos

    2012-01-01

    O objetivo do trabalho foi avaliar as alterações no teor de carboidratos em estacas lenhosas de mirtileiro das cultivares Delite, Powder Blue e Seleção 19. O trabalho foi dividido em dois experimentos, primeiramente foram analisados os teores de amido e de açúcares solúveis a partir de ramos coletados em quatro épocas (03-06, 04-07, 24-07 e 11-08-2008) e, posteriormente, avaliou-se o teor de carboidratos em estacas coletadas nas mesmas épocas citadas, porém submetidas ao enraizamento e avalia...

  6. NEM <em>PHYSIS>, NEM <em>PSYCHÉ>: O PAPEL DA ESTRUTURA NO REORDENAMENTO EPISTÊMICO DA PSICANÁLISE NEITHER PHYSIS, NOR PSYCHÉ: THE ROLE OF STRUCTURE IN EPISTEMOLOGICAL REORGANIZATION OF PSYCHOANALYSIS

    Gilson Iannini

    2010-01-01

    O principal objetivo deste trabalho é discutir o sentido do recurso de Lacan ao paradigma estrutural. A presente investigação enfatiza a função desse recurso no que tange as relações entre psicanálise e história das ciências. Freud, ao buscar estabelecer a identidade epistemológica da psicanálise precisou escolher entre <em>Naturwissenschaften em>e <em>Geisteswissenschaften. em>Sua opção pelo modelo das ciências naturais implica certo desconforto epistemol...

  7. Carcinoma hepatocelular metastático em Jaguatirica (Leopardus pardalis )

    Dayane F.H. Miranda; Francisco de A.L. Souza; Luciano S. Fonseca; Hatawa M. Almeida; Juliana F.V. Braga; Francisco A.L. Costa; Silvana M.M. de S. Silva

    2015-01-01

    RESUMO: O carcinoma hepatocelular (CHC) é uma neoplasia rara nos animais domésticos e em espécies selvagens foi relatado somente em antílopes, veado, cães da pradaria e furões, mas não existem relatos em Leopardus pardalis (jaguatirica). Este trabalho descreve um caso de carcinoma hepatocelular metastático em uma fêmea felina de aproximadamente 18 anos de idade, da espécie Leopardus pardalis, proveniente do Parque Zoobotânico de Teresina-PI, com histórico de anorexia, apatia e evolução ao óbi...

  8. Ensaios em instituições e desenvolvimento

    Costantini, Jaime Jordan

    2013-01-01

    Resumo: Esta tese se divide em três ensaios, os quais investigam: (a) As relações que existem entre democracia e desenvolvimento econômico na base do pensamento de Roberto Campos; (b) Os efeitos da instabilidade política no nível do investimento; e (c) Como a volatilidade e tendência dos termos de troca influenciam na acumulação de capital humano em um país em desenvolvimento que exporta matérias primas. De acordo com o pensamento de R. Campos, um país em desenvolvimento como o Brasil deve ac...

  9. Seletividade de oito inseticidas a predadores de lagartas em citros

    Galvan Tederson Luiz

    2002-01-01

    Full Text Available O objetivo deste trabalho foi avaliar a seletividade dos inseticidas abamectina, acefato, carbaril, deltametrina, fenitrotiom, fenpropatrina, paratiom metílico e triclorfom aos predadores Brachygastra lecheguana (Latreille, Protonectarina sylveirae (Saussure e Protopolybia exigua (Saussure (Hymenoptera: Vespidae em concentrações que corresponderam a 50% e 100% da dose recomendada para o controle de lagartas em citros. Os inseticidas estudados não foram seletivos em favor do predador P. sylveirae. Fenitrotiom, fenpropatrina, paratiom metílico e triclorfom não foram seletivos em favor dos predadores B. lecheguana e P. exigua. Abamectina, acefato e carbaril foram medianamente seletivos em favor de P. exigua, o mesmo foi verificado com abamectina e carbaril em favor de B. lecheguana. Acefato foi seletivo em favor de B. lecheguana e deltametrina em favor de P. exigua. As altas mortalidades causadas por deltametrina a P. sylveirae, triclorfom a B. lecheguana e acefato a P. exigua decresceram quando aplicados em subdose. B. lecheguana foi o predador mais tolerante à dose de acefato, seguido por P. exigua e P. sylveirae. O predador P. exigua foi mais tolerante à dose de deltametrina que B. lecheguana e P. sylveirae. As três espécies de predadores foram altamente suscetíveis às doses e subdoses de fenitrotiom, fenpropatrina e paratiom metílico, e à dose de triclorfom.

  10. Quantitative Evaluation of Fire and EMS Mobilization Times

    Upson, Robert

    2010-01-01

    Quantitative Evaluation of Fire and EMS Mobilization Times presents comprehensive empirical data on fire emergency and EMS call processing and turnout times, and aims to improve the operational benchmarks of NFPA peer consensus standards through a close examination of real-world data. The book also identifies and analyzes the elements that can influence EMS mobilization response times. Quantitative Evaluation of Fire and EMS Mobilization Times is intended for practitioners as a tool for analyzing fire emergency response times and developing methods for improving them. Researchers working in a

  11. Editorial - Investigar em Educação

    Estrela, Maria Teresa

    2005-01-01

    A revista Investigar em Educação pretende ocupar um espaço próprio, até aqui inexistente no nosso país: o de fazer anualmente a síntese da investigação publicada nos anos anteriores à publicação de cada número da revista, em domínios em que ela tenha sido significativa em termos de volume, relevância social ou inovação temática.

  12. Influence of Amitraz and Oxalic Acid on the Cuticle Proteolytic System of <em>Apis melliferaem> L. Workers

    Grzegorz Borsuk

    2012-08-01

    Full Text Available This work verifies that amitraz and oxalic acid treatment affect honeybee cuticle <em>proteolytic enzymes (CPE.em> Three bee groups were monitored: oxalic acid treatment, amitraz treatment, control. Electrophoresis of hydrophilic and hydrophobic CPE was performed. Protease and protease inhibitor activities (<em>in vitroem> and antifungal/antibacterial efficiencies (<em>in vivoem>, were analyzed. Amitraz and oxalic acid treatment reduced hydrophobic, but did not affect hydrophilic, protein concentrations and reduced both hydrophilic and hydrophobic body surface asparagine and serine protease activities in relation to most substrates and independently of pH. The activities of natural cuticle inhibitors of acidic, neutral, and alkaline proteases were suppressed as a result of the treatments, corresponding with reduced antifungal and antibacterial activity. Electrophoretic patterns of low-, medium-, and high-molecular-weight proteases and protease inhibitors were also affected by the treatments.

  13. Rhizonin A from <em>Burkholderia> sp. KCTC11096 and Its Growth Promoting Role in Lettuce Seed Germination

    Sang-Mo Kang

    2012-07-01

    Full Text Available We isolated and identified a gibberellin-producing <em>Burkholderia em>sp. KCTC 11096 from agricultural field soils. The culture filtrate of plant growth promoting rhizobacteria (PGPR significantly increased the germination and growth of lettuce and Chinese cabbage seeds. The ethyl acetate extract of the PGPR culture showed significantly higher rate of lettuce seed germination and growth as compared to the distilled water treated control. The ethyl acetate fraction of the <em>Burkholderia em>sp. was subjected to bioassay-guided isolation and we obtained for the first time from a <em>Burkholderia em>sp. the plant growth promoting compound rhizonin A (1, which was characterized through NMR and MS techniques. Application of various concentrations of 1 significantly promoted the lettuce seed germination as compared to control.

  14. Development of Microsatellite Markers for the Korean Mussel, <em>Mytilus coruscusem> (Mytilidae Using Next-Generation Sequencing

    Hye Suck An

    2012-08-01

    Full Text Available <em>Mytilus coruscusem> (family Mytilidae is one of the most important marine shellfish species in Korea. During the past few decades, this species has become endangered due to the loss of habitats and overfishing. Despite this species’ importance, information on its genetic background is scarce. In this study, we developed microsatellite markers for <em>M.> coruscusem> using next-generation sequencing. A total of 263,900 raw reads were obtained from a quarter-plate run on the 454 GS-FLX titanium platform, and 176,327 unique sequences were generated with an average length of 381 bp; 2569 (1.45% sequences contained a minimum of five di- to tetra-nucleotide repeat motifs. Of the 51 loci screened, 46 were amplified successfully, and 22 were polymorphic among 30 individuals, with seven of trinucleotide repeats and three of tetranucleotide repeats. All loci exhibited high genetic variability, with an average of 17.32 alleles per locus, and the mean observed and expected heterozygosities were 0.67 and 0.90, respectively. In addition, cross-amplification was tested for all 22 loci in another congener species, <em>M.> <em>galloprovincialis.> None of the primer pairs resulted in effective amplification, which might be due to their high mutation rates. Our work demonstrated the utility of next-generation 454 sequencing as a method for the rapid and cost-effective identification of microsatellites. The high degree of polymorphism exhibited by the 22 newly developed microsatellites will be useful in future conservation genetic studies of this species.

  15. Controle Químico de Antracnose em Mudas de Pupunheira em Viveiro Chemical Control of Anthracnose on Peach Palm Transplants in Orchard

    Rudimar Mafacioli; Dauri José Tessmann; Álvaro Figueredo dos Santos; João Batista Vida

    2011-01-01

    A antracnose, causada pelo fungo <em>Colletotrichum loeosporioides>, é a principal doença da parte aérea da pupunheira (<em>Bactris gasipaes em>var gasipaes) em viveiros de mudas no Centro-Sul do Brasil. O objetivo do trabalho foi avaliar a eficiência de novas formulações de fungicidas no controle de antracnose em mudas de pupunheira, na fase de viveiro. O ensaio foi conduzido no período de abril a agosto de 2006, com o delineamento experimental em blo...

  16. NÍVEL DE INFESTAÇÃO DA BROCA DOS CITROS, Diploschema rotundicolle (SERVILLE, 1834) EM CINAMOMO E PLANTAS CÍTRICAS, EM SANTA MARIA - RS

    Dionísio Link; Ervandil Corrêa Costa

    1994-01-01

    RESUMO Aspectos da biologia e frequência de infestação de Diploschema rotundicolle (Serville, 1834) foram estudados em cinamomo e plantas cítricas, em Santa Maria - RS, durante os anos de 1989 e 1990. Há preferência para oviposição em citros. O ciclo evolutivo é maior em citros que em cinamomo. Emergem menos adultos em citros que em cinamomo. Há maior incidência de predadores nas galerias larvais, nas plantas cítricas.

  17. QUALIDADE MICROBIOLÓGICA E NITRATO EM ÁGUAS MINERAIS E DE POÇOS DE JABOTICABAL-SP

    LOPES, Laudicéia Giacometti

    2008-10-01

    Full Text Available The present work aimed the verification of the hygienic-sanitary quality, and the concentrationof nitrates in bottled water and from private wells used by the population of Jaboticabal, SP, Brazil. For bottledwater, three brand marks, three size bottles (20 L, 1.5 L, 0.2 L and five batches were analyzed. Waters from wellswere analyzed in dry and rainy periods. The varieties analyzed in both cases were: Pseudomonas aeruginosa,sulfide reducers clostridium, total coliforms, Escherichia coli, enterococcus, mesophilic aerobic microorganismsand nitrate. The results indicated there’s no uniformity in the quality of waters bottled in 20 L containers for thedifferent batches and for the three brand marks, due, possibly, to deficiency in their preparation for reuse. From 225analyzed samples, 37% presented themselves as out of standard of potability (Resolução 274/05 e 275/05. Fromthe seven wells analyzed, Iit was verified that three wells had the microbiological quality of its water influenced bypluvial precipitations and two wells presented high level of nitrate. The results showed that 2.8% of water from wells were out of potability standard (Portaria 518/04.O presente trabalho teve como objetivos avaliar a qualidade higiênico-sanitária e a concentraçãode nitratos em águas engarrafadas e de poços particulares utilizadas pela população de Jaboticabal - SP. Para aságuas engarrafadas, foram estudadas três marcas, três volumes de embalagens (20 L; 1,5 L; 0,2 L e cinco lotes.As águas de poços foram analisadas em períodos de seca e de chuva. As variáveis analisadas nos dois casosforam: Pseudomonas aeruginosa, clostridios sulfito-redutores, coliformes totais, Escherichia coli, enterococos,microrganismos aeróbios mesófilos e teores de nitrato. Os resultados evidenciaram que não existe uniformidadede qualidade das águas condicionadas em galões de 20 L, para os diferentes lotes e para as três marcas, o que sedeve possivelmente à defici

  18. Il Vespertilio mustacchino <em>Myotis mystacinusem> (Kuhl, 1817 (Chiroptera, Vespertilionidae nuova specie per la Calabria

    Dino Scaravelli

    2004-06-01

    Full Text Available Abstract <em>Myotis mystacinusem> (Kuhl, 1817 (Chiroptera, Vespertilionidae new species for Calabria region, southern Italy A young male of whiskered bat <em>Myotis mystacinusem>, dead the 13 July of 1995 in the building of Ecology Department, University of Calabria, in Rende (Cosenza, was found during the taxonomic revision of the bats in the Theriological Collection of "Museo di Storia Naturale della Calabria ed Orto Botanico" of the University of Calabria. This is the southern most sighting of the species in Italy. The bat checklist of the Calabria region includes now 21 species.

  19. Content marketing em Portugal : um estudo de caso em agências de publicidade/comunicação

    Machado, André Filipe Couto

    2014-01-01

    Mestrado em Marketing Este Trabalho Final de Mestrado tem como objeto de estudo o content marketing em Portugal. Numa altura em que a evolução tecnológica e comunicacional potenciou os atributos dos conteúdos e suas mensagens, esta dissertação pretende conhecer de que forma é trabalhado em Portugal o content marketing pelas agências de publicidade/comunicação portuguesas e de que forma elas veem as marcas/empresas a adotar este conceito. O estudo pretende responder às seguintes pergunt...

  20. Anemia em lactentes de baixa renda em aleitamento materno exclusivo Anemia in low-income exclusively breastfed infants

    Marco Antonio A. Torres; Josefina A.P. Braga; José Augusto A.C. Taddei; Fernando J. Nóbrega

    2006-01-01

    OBJETIVO:Verificar o comportamento dos valores da hemoglobina e a prevalência de anemia entre lactentes de termo de 3 a 6 meses de idade em aleitamento materno exclusivo. MÉTODOS: Estudo transversal em 242 lactentes de 3 a 6 meses de idade com peso de nascimento superior a 2.500 g, em aleitamento materno exclusivo e em acompanhamento no Programa de Promoção do Crescimento e Desenvolvimento do Lactente do Programa Einstein na Comunidade de Paraisópolis. A dosagem de hemoglobina foi realizada p...

  1. Chiral Zn(II-Bisamidine Complex as a Lewis-Brønsted Combined Acid Catalyst: Application to Asymmetric Mukaiyama Aldol Reactions of <em>α>-Ketoesters

    Ryo Gotoh

    2012-07-01

    Full Text Available Focusing on the steric and electronic properties of the resonance-stabilized amidine framework, a cationic metal-bisamidine complex was designed as a conjugated combined Lewis-Brønsted acid catalyst. The chiral Zn(II-bisamidine catalyst prepared from the 2,2'-bipyridyl derived bisamidine ligand, ZnCl2, and AgSbF6 promoted asymmetric Mukaiyama aldol reaction of <em>α>-ketoester and <em>α,α>-disubstituted silyl enol ether to afford the <em>α>-hydroxyester having sequential quarternary carbons in good yield, albeit with low enantioselectivity. Addition of 1.0 equivalent of the fluoroalcohol having suitable acidity and bulkiness dramatically increased the enantioselectivity (up to 68% <em>ee>. DFT calculations suggested that this additive effect would be caused by self-assembly of the fluoroalcohol on the Zn(II-bisamidine catalyst.

  2. Soldagem em operação: parte 1 - efeito do arrefecimento causado pelo fluido em tubulação de espessura 11 mm In-service welding: part 1: effect of freezing caused by fluid in 11 mm thick pipe

    Paulo Faria

    2012-12-01

    Full Text Available Este trabalho avalia, na soldagem em operação, a influência do arrefecimento causado por um líquido fluindo em contato com a parede interna de uma tubulação sendo soldada por TIG (GTAW e eletrodo revestido (SMAW. A soldagem foi realizada na ligação de conexões de aço ASTM A105 a um tubo API 5L Gr X60 com espessura de 11 mm e de 6 mm. A circulação do fluido foi feita com água potável em duas faixas de temperatura, de 6 a 10ºC e 26 a 36ºC. Foram simuladas quatro juntas soldadas, avaliadas por meio de ensaios não destrutivos (inspeção visual, líquido penetrante, partículas magnéticas e ultrasom. Esta parte do trabalho apresenta os resultados dos ensaios destrutivos (tração, dobramento, impacto, fratura e dureza e análise macrográfica e micrográfica para o tubo de 11 mm de espessura. As juntas soldadas não apresentaram os problemas típicos da soldagem em operação, como trincas a frio e risco de perfuração. Os procedimentos de soldagem puderam ser qualificados, atendendo os critérios de aceitação das normas pertinentes. Foi possível concluir que o resfriamento acelerado causado pelo fluido em circulação, elevou consideravelmente a taxa de resfriamento na superfície interna do tubo. O efeito do arrefecimento causado pelo fluido no interior do tubo foi mais significativo que a temperatura deste fluido, tendo provocado o aumento na dureza da zona fundida e zona termicamente afetada e reduzido o alongamento no ensaio de tração, porém ainda em valores adequados para o tubo de 11 mm de espessura.This work evaluates for in-service welding, the influence of cooling caused by a liquid flowing in contact with the inner wall of a pipe being welded by TIG (GTAW and stick electrode (SMAW. The welding was done to join connections of an ASTM A105 to an 11mm and 6 mm thick API 5L Gr X60 steel pipe. The fluid circulation was made with potable water within two temperature ranges, of 6 to 10ºC and 26 to 36ºC. Four welded

  3. Green Biosynthesis of Silver Nanoparticles Using <em>Callicarpa maingayiem> Stem Bark Extraction

    Mohammed Zidan

    2012-07-01

    Full Text Available Different biological methods are gaining recognition for the production of silver nanoparticles (Ag-NPs due to their multiple applications. The use of plants in the green synthesis of nanoparticles emerges as a cost effective and eco-friendly approach. In this study the green biosynthesis of silver nanoparticles using <em>Callicarpa maingayi em>stem bark extract has been reported. Characterizations of nanoparticles were done using different methods, which include; ultraviolet-visible spectroscopy (UV-Vis, powder X-ray diffraction (XRD, transmission electron microscopy (TEM, scanning electron microscopy (SEM, energy dispersive X-ray fluorescence (EDXF spectrometry, zeta potential measurements and Fourier transform infrared (FT-IR spectroscopy. UV-visible spectrum of the aqueous medium containing silver nanoparticles showed absorption peak at around 456 nm. The TEM study showed that mean diameter and standard deviation for the formation of silver nanoparticles were 12.40 ± 3.27 nm. The XRD study showed that the particles are crystalline in nature, with a face centered cubic (fcc structure. The most needed outcome of this work will be the development of value added products from <em>Callicarpa maingayi em>for biomedical and nanotechnology based industries.

  4. Microbial Enhance of Chitosan Production by <em>Rhizopus arrhizusem> Using Agroindustrial Substrates

    Marta C. Freitas Silva

    2012-04-01

    Full Text Available This study investigated the potential of <em>Rhizopus arrhizusem> UCP 402 for producing chitosan using corn steep liquor and honey as agroindustrial nitrogen and carbon sources. A complete factorial design was used to assess the improved biomass and chitosan production. The results were evaluated using Pareto charts (Statistica 7.0 software. The chitosan obtained was characterized by X-ray diffraction. The cristallinity index (IC, and infrared spectroscopy (FTIR were used to evaluate the degree of deacetylation (DD %. The morphological aspects of the <em>R. arrhizusem> were evaluated by measuring the diameter of the colonies by light microscopy. The results obtained showed higher biomass and chitosan yields (20.61 g/L and 29.3 mg/g, respectively, in the selected assays. The characterization of the macromolecular arrangement of chitosan showed a crystallinity index compatible with the literature, and the infrared peaks confirmed a degree of 86%. The experimental data obtained suggest that adding honey to corn steep liquor is a promising way to improve microbiological chitosan production.

  5. Function and 3D Structure of the <em>N>-Glycans on Glycoproteins

    Yoshiki Yamaguchi

    2012-07-01

    Full Text Available Glycosylation is one of the most common post-translational modifications in eukaryotic cells and plays important roles in many biological processes, such as the immune response and protein quality control systems. It has been notoriously difficult to study glycoproteins by X-ray crystallography since the glycan moieties usually have a heterogeneous chemical structure and conformation, and are often mobile. Nonetheless, recent technical advances in glycoprotein crystallography have accelerated the accumulation of 3D structural information. Statistical analysis of “snapshots” of glycoproteins can provide clues to understanding their structural and dynamic aspects. In this review, we provide an overview of crystallographic analyses of glycoproteins, in which electron density of the glycan moiety is clearly observed. These well-defined <em>N>-glycan structures are in most cases attributed to carbohydrate-protein and/or carbohydrate-carbohydrate interactions and may function as “molecular glue” to help stabilize inter- and intra-molecular interactions. However, the more mobile <em>N>-glycans on cell surface receptors, the electron density of which is usually missing on X-ray crystallography, seem to guide the partner ligand to its binding site and prevent irregular protein aggregation by covering oligomerization sites away from the ligand-binding site.

  6. Para uma genealogia do debate em torno da viabilidade do Estado em Timor‑Leste

    Nuno Canas Mendes

    2014-09-01

    Full Text Available O artigo procura traçar uma genealogia do debate em torno da construção e da viabilidade do Estado em Timor‑Leste, desde os alvores da ideia de independência aos nossos dias: percorre o período 1974‑75, a ocupação indonésia até ao início e termo da administração internacional das Nações Unidas (1999‑2002 e finalmente a assunção da soberania em 2002, com os subsequentes desafios e dificuldades desde então sentidos. Este debate reflete tensões políticas de âmbito regional e internacional e deve ser inserido nos contextos históricos específicos em que ocorreu tal produção discursiva. Para além da definição de um quadro conceptual que se ensaia na aplicação ao caso, serão analisadas as posições dos principais intervenientes externos no processo, Estados e organizações internacionais, cujas motivações serão objeto de reflexão.

  7. <em>Crocidura> populations (Mammalia, Soricidae from the Sicilian-Maltese insular area

    Maurizio Sarà

    1996-12-01

    Full Text Available Abstract Recent studies have shown the presence of a new endemic species of Soricidae, <em>Crocidura siculaem>, in the Mediterranean area. Its karyotype consists of 36 chromosomes (NF = 56, NFa = 52 as previously recorded in specimens from Sicily and Gozo (Malta. Karyological analysis carried out in the present study on specimens from Marettimo (Egadi and Ustica and on two additional Sicilian localities proved the presence of the same <em>C. siculaem> karyotype. The multivariate analysis of skull and mandible of these populations revealed a pattern of geographic variation which is mainly related to a size decrease (76% of the total variability accounted for in shrews living in the small islands around Sicily. The body biometrics of these insular shrews follows this trend, with some exceptions such as in Ustica, where shrews are relatively bigger. The shrews from Ustica show also melanic fur, which is darker than the grey-witheish colour found in conspecific populations. Such a phenotype could be the result of adaptation to the volcanic environment on this island. This latter population is, of all the small islands, the most divergent and differentiated from the mother-island; if considering its skull morphometrics (i.e. the residual 24% of total variability and its body biometrics.

  8. Bupivacaína 0,15% hipobárica versus lidocaína 0,6% hipobárica para raquianestesia posterior em cirurgia anorretal ambulatorial Bupivacaína 0,15% hipobárica versus lidocaína 0,6% hipobárica para raquianestesia posterior en cirugía anorrectal ambulatorial Hypobaric 0.15% bupivacaine versus hypobaric 0.6% lidocaine for posterior spinal anesthesia in outpatient anorectal surgery

    Luiz Eduardo Imbelloni

    2010-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Baixas doses de bupivacaína e lidocaína têm sido usadas para raquianestesia em cirurgia ambulatorial. O objetivo deste estudo foi comparar a bupivacaína com a lidocaína ambas em solução hipobárica em pacientes ambulatoriais de cirurgia anorretal. MÉTODO: Dois grupos de 75 pacientes, estado físico ASA I-II, candidatos a cirurgia anorretal em posição de canivete, receberam 3 mL (4,5 mg de bupivacaína 0,15% hipobárica ou 3 mL (18 mg de lidocaína 0,6% hipobárica. Foram comparados a seletividade do bloqueio, a qualidade da analgesia cirúrgica, a intensidade do bloqueio motor e o tempo de recuperação no paciente de cirurgia ambulatorial. Após a alta foi mantida comunicação diária por telefone até o 3º dia e depois no 30º de pós-operatório. RESULTADOS: O bloqueio foi adequado para cirurgia em todos os pacientes. O nível médio da dispersão cefálica foi L1 com variação de T10-L3 com a bupivacaína e L1 com variação T11-L2 com a lidocaína. Não foi observado bloqueio motor em 135 pacientes (65 da bupivacaína x 70 da lidocaína. Hipotensão e bradicardia não foram observadas em nenhum paciente. A média de duração do bloqueio sensitivo foi de 99,1 (11,0 minutos com a bupivacaína e 64,1 (7,6 minutos com a lidocaína, com diferença significante (p JUSTIFICATIVA Y OBJETIVOS: Bajas dosis de bupivacaína y lidocaína han sido usadas para raquianestesia en cirugía ambulatorial. El objetivo de este estudio fue comparar la bupivacaína con la lidocaína ambas en solución hipobárica en pacientes ambulatoriales de cirugía anorrectal. MÉTODOS: Dos grupos de 75 pacientes, estado físico ASA I-II, candidatos a cirugía anorrectal en posición prona (prone jacknife, que recibieron 3 mL (4,5 mg de bupivacaína 0,15% hipobárica o 3 mL (18 mg de lidocaína 0,6% hipobárica. Fueron comparados la selectividad del bloqueo, la calidad de la analgesia quirúrgica, la intensidad del bloqueo motor y el

  9. Determinantes individuais e contextuais da carie em criancas brasileiras de 12 anos em 2010

    Maria do Carmo Matias Freire

    2013-12-01

    Full Text Available OBJETIVO: Estimar a prevalência e gravidade de cárie em crianças brasileiras e sua associação com fatores individuais e contextuais. MÉTODOS: Foram utilizados os dados da Pesquisa Nacional de Saúde Bucal (SBBrasil 2010, em uma amostra de 7.247 crianças de 12 anos. Os dados foram coletados por meio de exames clínicos e entrevistas. As variáveis dependentes foram as prevalências de cárie (dentes permanentes cariados, perdidos ou obturados [CPOD] ≥ 1 e CPOD ≥ 4. Foram realizadas análises bivariadas (teste de Rao-Scott e multinível (regressão de Poisson. As variáveis individuais foram sociodemográficas, condição periodontal e relato de incômodo ao escovar os dentes. Os fatores contextuais foram a presença de água fluoretada, a porcentagem de domicílios ligados à rede de abastecimento de água e a renda mediana do município. RESULTADOS: A prevalência de CPOD ≥ 1 foi 56,0%. O CPOD médio foi igual a 2,04 (IC95% 1,76;2,31 e 22,2% das crianças tinham CPOD ≥ 4. A experiência de cárie foi significantemente mais elevada em crianças de cor de pele preta, parda e amarela; em famílias com renda mais baixa; em crianças com cálculo dentário ou sangramento gengival; e naquelas que relataram incômodo ao escovar. Viver em cidades sem água fluoretada, com menor cobertura da rede de abastecimento de água e com renda mediana baixa foram fatores contextuais associados à doença. CONCLUSÕES: A prevalência de cárie em crianças brasileiras de 12 anos foi baixa, de acordo com os critérios da Organização Mundial da Saúde. Houve significantes desigualdades geográficas e socioeconômicas nos níveis da doença.

  10. Realismo e utopia em Robert Michels

    Pedro Floriano Ribeiro

    2012-11-01

    Full Text Available O artigo aponta e discute as principais influências teóricas e políticas de Robert Michels na construção de Sociologia dos partidos políticos, tentando ir além das fontes mais conhecidas, como Gaetano Mosca, Vilfredo Pareto, Max Weber e Gustave Le Bon. Como Michels não se preocupou em construir definições claras sobre seus conceitos principais, procurou-se extrair a essência de seu raciocínio, apresentando as concepções e influências teóricas predominantes no livro, e destacando as mudanças entre a primeira edição, de 1911, e a segunda, de 1925. Para tanto, realizou-se um estudo das 989 notas explicativas desta segunda edição (além do texto principal em si. Além de discutir as fontes explicitadas no livro, o artigo também esboça uma "análise genética" da obra, levantando alguns fatos biográficos prévios à sua publicação e no intervalo entre as duas edições, e recorrendo, ainda, a outros trabalhos de Michels. Após debater as concepções e críticas do autor sobre democracia, revolução, socialismo, sindicalismo e anarquismo, o artigo termina com um balanço sobre as fragilidades e contribuições da obra de Michels, destacando que a chave para se compreender vida e obra do autor reside em perceber as tensas disjuntivas estabelecidas entre realismo e utopia e entre o Michels militante e o Michels analista.

  11. Reciclando a cidadania em rede interdisciplinar

    Foresti, Andréa Jaeger

    2006-01-01

    Full Text Available Este texto tem por objetivo evidenciar o processo de constituição da ONG REDECRIAR, diretamente vinculada ao Projeto “Reciclando a Cidadania em Rede Interdisciplinar”, examinando os elementos que nele estão imbricados. O primeiro elemento se refere ao chamado Terceiro Setor, o qual se configurou como espaço de intervenção profissional, viabilizando a articulação de conhecimentos interdisciplinares, norteados por princípios éticos e políticos, que buscam garantir a universalidade das políticas sociais públicas. O segundo elemento a ser examinado é o Desenvolvimento Sustentável que se conformou como tema central das ações planejadas por abarcar, em seu conceito, o equilíbrio entre as questões ambientais, sociais e econômicas. Esta conformação determinou a efetividade da proposta, ao delinear o conteúdo das intervenções, direcionado a um públicoalvo coletivo. Nessa perspectiva, a implementação dos pressupostos metodológicos do Trabalho, em Redes Sociais, constitui-se como terceiro elemento imbricado no processo de constituição da REDECRIAR, corroborando com a reciclagem – aproximação prática de um novo conceito – da Cidadania, efetivado por um grupo de profissionais do Serviço Social, Biologia e Nutrição

  12. DETERMINAÇÃO DO POLIPEPTÍDEO RICO EM PROLINA (PRP): PESQUISA DE METODOLOGIA EM LATICÍNIOS PARA FUTURA UTILIZAÇÃO EM LEITE HUMANO

    Karina Merini Tonon; Mercedes Gabriela Ratto Reiter; Mauro Scharf

    2010-01-01

    Vários estudos identificaram a presença de um polipeptídeo rico em prolina (PRP) no leite de ovelha e de vaca e estudos subsequentes comprovaram o seu efeito positivo no tratamento do Alzheimer. Este trabalho teve como objetivo investigar uma metodologia viável para determinar a presença do aminoácido prolina em produtos lácteos como leite, queijo e iogurte, para futura utilização em leite humano.

  13. Custos indirectos associados à obesidade em Portugal

    Pereira, João; Mateus, Céu

    2003-01-01

    RESUMO - A obesidade constitui um importante problema de saúde pública com consequências económicas de grande dimensão. Os obesos têm um risco acrescido de contrair doenças e de sofrer morte prematura devido a problemas como a diabetes, hipertensão arterial, AVC, insuficiência cardíaca e algumas neoplasias malignas. O presente estudo tem como objectivo estimar o custo económico indirecto (valor da produção perdida) associado à obesidade em Portugal no ano de 2002. O...

  14. Problemas psiquiátricos em geriatria

    Marcelo Blaya

    1960-06-01

    Full Text Available Foi apresentado um resumo das idéias comumente aceitas em psiquiatria dinâmica com relação aos problemas emocionais da velhice. A necessidade de uma solução eclética para esta questão de crescente importância na sociedade hodierna não impede que se utilize, com vantagem, uma orientação psicanalítica no tratamento dêsses indivíduos. No caso apresentado acham-se ilustrados alguns pontos de vista do autor.

  15. Densità di Lepre (<em>Lepus europaeusem> e Silvilago (<em>Sylvilagus floridanusem> in ambienti planiziali

    Sandro Bertolino

    2003-10-01

    Full Text Available Il silvilago (<em>Sylvilagus floridanusem> è un leporide d?origine nordamericana, introdotto in Italia a partire dal 1966 a scopo venatorio. Attualmente la specie è diffusa soprattutto in Piemonte e nella parte occidentale della Lombardia. Il silvilago potrebbe interferire con l?autoctona lepre comune (<em>Lepus europaeusem>, anche se i dati al riguardo sono limitati. Nell?autunno-inverno 2002-2003 abbiamo condotto dei censimenti notturni con faro in alcune aree protette lungo il fiume Po (Breme, Fontanetto Po, Pobietto e il torrente Orba (Predosa, Monferrino. I censimenti erano effettuati percorrendo con automezzo itinerari prefissati. Il territorio ai lati del percorso era illuminato con faro alogeno (100 W, segnando periodicamente l?ampiezza della fascia illuminata. L?area effettivamente censita è stata in seguito verificata mediante GIS ArcView, usando una cartografia informatizzata d?uso del suolo (1:10.000. L?uso reale del suolo al momento del censimento (esempio: arato, grano o stoppie è stato verificato durante sopralluoghi diurni. Per ogni area sono state condotte tre repliche del censimento. Di seguito sono riportate per ogni località le densità rilevate (individui/Km² rispettivamente di lepre comune e silvilago. Breme (1,7; 32,8, Fontanetto Po (0; 4,4, Pobietto (0,3; 13,9, Predosa (1,1; 19,5, Monferrino (29,6; 110,4. Solo l?area di Monferrino è risultata ospitare una popolazione di lepri con densità corrispondente a territori ad alta vocazionalità. La zona censita si trova a cavallo tra una riserva regionale e una ZRC della Provincia di Alessandria. Nella stessa area il silvilago presenta una densità elevata, ma comunque inferiore ai valori massimi riportati negli Stati Uniti. Nelle altre aree sono state osservate pochissime lepri. Tale scarsità è probabilmente legata alla presenza di popolazioni relitte e habitat non sempre idonei. Il silvilago, per quanto non abbondante come a Monferrino, è presente con popolazioni

  16. Graffiti e street art em Portugal

    Simões, Marta Correia

    2014-01-01

    O seguinte trabalho tem como principal objectivo introduzir o estudo do graffiti e da street art no seio da história da arte em Portugal, como uma forma de arte contemporânea. O graffiti tem vindo a acompanhar a humanidade ao longo da história. De uma forma inconstante, este teve as mais diversas utilizações e é hoje considerado como um movimento artístico. Partindo de um estudo da prática do graffiti com início nas cidades americanas, procurou-se apresentar o processo que culminou com a s...

  17. ULCERA GASTRODUODENAL EM CÃES

    Francisco Assis Uma Costa

    1993-12-01

    Full Text Available As ulcerações no sistema digestivo de cães são consideradas raras. São descritos dois casos de úlcera gastroduodenal em cães. O primeiro animal apresentou úlcera no duodeno próxima!. O segundo mostrou úlcera perfurada na região pilórica do estômago. Nenhum dos animais apresentou evidências de sangramento, mas as lesões eram profundas e arredondadas. Não houve evidência de patologias concorrentes.

  18. ULCERA GASTRODUODENAL EM CÃES

    Francisco Assis Uma Costa; Silvaria Maria Medeiros de Sousa Silva; Ana Maria Quessada

    1993-01-01

    As ulcerações no sistema digestivo de cães são consideradas raras. São descritos dois casos de úlcera gastroduodenal em cães. O primeiro animal apresentou úlcera no duodeno próxima!. O segundo mostrou úlcera perfurada na região pilórica do estômago. Nenhum dos animais apresentou evidências de sangramento, mas as lesões eram profundas e arredondadas. Não houve evidência de patologias concorrentes.

  19. EM threat analysis for wireless systems.

    Burkholder, R. J. (Ohio State University Electroscience Laboratory); Mariano, Robert J.; Schniter, P. (Ohio State University Electroscience Laboratory); Gupta, I. J. (Ohio State University Electroscience Laboratory)

    2006-06-01

    Modern digital radio systems are complex and must be carefully designed, especially when expected to operate in harsh propagation environments. The ability to accurately predict the effects of propagation on wireless radio performance could lead to more efficient radio designs as well as the ability to perform vulnerability analyses before and after system deployment. In this report, the authors--experts in electromagnetic (EM) modeling and wireless communication theory--describe the construction of a simulation environment that is capable of quantifying the effects of wireless propagation on the performance of digital communication.

  20. Telepoesis.net - Poesia em Rede

    Torres, Rui

    2005-01-01

    Partindo da apresentação de exemplos de poesia criada para o meio digital, pretende-se com este artigo propor uma reflexão acerca das novas textualidades emergentes com as tecnologias digitais interactivas. Assim, acreditando que as características da hipermédia constituem um terreno fértil para o experimentalismo literário, critica-se uma postura de mera remediação dos arquétipos analógicos para os meios digitais, argumentando a favor da criatividade colectiva em rede enquanto possibilidade ...