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Sample records for 3m cavilon sobre

  1. Evaluación in vivo mediante microscopia confocal del efecto protector de la película barrera no irritante 3M Cavilon sobre la piel perilesional In vivo evaluation using confocal microscopy of protective effect of no-sting barrier film 3M Cavilon on periwound skin

    Teresa Segovia Gómez

    2008-03-01

    Full Text Available Tradicionalmente, el manejo de las úlceras cutáneas incluye medidas que facilitan la cicatrización, tales como el buen desbridamiento, ya sea médico o quirúrgico, apósitos oclusivos, tratamiento de infección y buena nutrición; sin embargo, es importante la valoración y el tratamiento de la piel perilesional. En este sentido, recientemente, diversos autores han descrito la coexistencia de trastornos nutricionales y tróficos en la misma, muchos de ellos de causa iatrogénica, y donde el uso de la película barrera no irritante 3M Cavilon puede ser un pilar importante para una buena respuesta al tratamiento. Los objetivos que se persiguen con el presente estudio pretenden identificar las características confocales de la piel perilesional de las úlceras venosas y evaluar los cambios dinámicos que experimenta la misma tras el uso adyuvante de la película barrera no irritante 3M Cavilon en su tratamiento. Para ello, pacientes afectos con úlceras venosas de larga evolución fueron tratados durante una semana de manera convencional utilizando, además del material de cura, 3M Cavilon en una sección de la piel perilesional. La zona de piel perilesional en la que no se utilizó 3M Cavilon nos sirvió como control. Las úlceras fueron evaluadas por inspección visual, fotografía digital y microscopía confocal in vivo previa al uso de 3M Cavilon y a la semana de aplicación diaria del producto. Las úlceras demostraron una mejoría clínica. La evaluación con microscopía confocal de reflectancia evidenció importante mejoría histológica del área tratada con 3M Cavilon comparada con el área no tratada con este apósito. En el momento inicial del estudio, la piel perilesional demostró la presencia de áreas de necrosis epidérmicas, espongiosis, infiltración por células inflamatorias y vasodilatación prominente. Tras la semana de tratamiento, aunque todo el área de piel perilesional demostró mejoría, en el área tratada con 3M

  2. Synthesis and elecrophysical properties of superionic conductors Li3M2(PO4)3 (M = Fe, Sc, Cr)

    Detailed study of a new class of superionic conductors Li3M2(PO4)3 (M = Fe, Sc, Cr) is conducted. Optimal conditions of synthesis and growing of monocrystals of individual compounds and solid solutions are found. Electrophysical characteristics of the matrials obtained are investigated. Effect of isomorphous substitutions in Li3M2(PO4)3 structural type on electrophysical properties is studied. 18 refs.; 10 figs.; 6 tabs

  3. Fabrication and metrology study for M3M of TMT

    Luo, Xiao

    2014-09-01

    The M3M (Mirror 3 Mirror) of TMT (Thirty Meter Telescope) project is a3.5m×2.5m solid flat elliptical mirror. CIOMP is responsible for the fabrication of the M3M. A primary study on the fabrication and metrology is done in the past 2 years, and this paper introduces our work on the project. The fabrication strategy is based on large orbital tools and a plan combining with multiple measure methods is developed based on the requirement of M3M. A concept of dualsupporting system is also studied in the program to reduce the effect of gravity deformation.

  4. Advancement of neutron radiography technique in JRR-3M

    The JRR-3M thermal neutron radiography facility (JRR-3M TNRF) was completed in the JRR-3M of the Japan Atomic Energy Research Institute in 1991 and has been utilized as research tools for various kinds of research fields such as thermal hydraulic researches, agricultural researches, medical researches, archaeological researches and so on. High performance of the JRR-3M TNRF such as high neutron flux, high collimator ratio and wide radiographing field has enabled advanced researches and stimulated developments of advanced neutron radiography (NR) systems for higher spatial resolution and for higher temporal resolution. Static NR systems using neutron imaging plates or cooled CCD camera with high spatial resolution, a real-time NR system using a silicon intensifier target tube camera and a high-frame-rate NR system using a combination of an image intensifier and a high speed digital video camera with high temporal resolution have been developed to fill the requirements from researchers. (author)

  5. MISC_0_3M_CLR_2008

    Vermont Center for Geographic Information — This dataset (MISC_0_3M_CLR_2008) includes truecolor ortho imagery covering an area north and south of the VT/Canadian border. VCGI extracted the imagery from a...

  6. MISC_0_3M_CLR_2009

    Vermont Center for Geographic Information — This dataset (MISC_0_3M_CLR_2009)includes truecolor ortho imagery covering the Barre-Monteplier (Capital Region) of Vermont. VCGI reprojected the imagery from its...

  7. Peripheral plasma characteristics near LCMS in URAGAN-3M

    The study of peripheral plasma parameters and of physical processes in this plasma will enable in particular to find out the mechanisms responsible for particle and energy transport from the confinement volume. The investigating of main peripheral plasma parameters in the URAGAN-3M (U-3M) torsatron was carried out when the bulk plasma was produced and heated in ICR conditions. The radial density, electron temperature, and floating potential profiles near the last closed magnetic surface (LCMS) have been measured at the active stage of the discharge. In particular, the effect of RF fields on generation of an additional positive potential near the LCMS has been shown. 11 refs, 4 figs

  8. Piezoelectric gravitational antennas for use at 3 m 0K

    The design of a gravitational antenna consisting of a relatively large piezoelectric quartz crystal cooled to 3 m 0K is presented. Calculations show that the use of the piezoelectric output to detect signals results in a simplification of the apparatus with no loss in sensitivity as compared to that attainable with similar antennas employing magnetic-displacement detectors. For both types of antennas the sensitivity is considerably better than that required to detect thermal oscillations at 3 m 0K and compares favorably with that attainable with massive room-temperature antennas

  9. 76 FR 70443 - Decision on Waiver Application From 3M

    2011-11-14

    ... waiver request and requested public comment in the Federal Register issue of September 27, 2011 (76 FR... AGENCY Decision on Waiver Application From 3M AGENCY: Environmental Protection Agency (EPA). ACTION..., excluding legal holidays. The telephone number of the EPA/DC Public Reading Room is (202) 566-1744, and...

  10. Centralized radiation monitoring system for the JRR-3M

    This paper describes the outline of centralized radiation monitoring system for the JRR-3M and its functions such as the acquisition, the monitoring, the filing, the display and the statistical analysis of the data measured and the diagnostic program for the projection of the phenomena of the events to offer the measures needed. (author)

  11. Stephen Hawking bags big new 3m physics prize

    Johnston, Hamish

    2013-01-01

    A massive 3m in prize money has gone to the British cosmologist Stephen Hawking for his work on black holes, quantum gravity and the early universe. The award is one of two "special fundamental physics prizes" from the Fundamental Physics Prize Foundation, which was set up earlier this year by the Russian physicist-turned-entrepreneur Yuri Milner.

  12. Testing of the 3M Company Composite Conductor

    Stovall, John P [ORNL; Rizy, D Tom [ORNL; Kisner, Roger A [ORNL

    2010-10-01

    The 3M Company has developed a high-temperature low-sag conductor referred to as Aluminum-Conductor Composite-Reinforced or ACCR. The conductor uses an aluminum metal matrix material to replace the steel in conventional conductors. The objective of this work is to accelerate the commercial acceptance by electric utilities of this new conductor design by testing four representative conductor classes in controlled conditions. A unique facility called the Powerline Conductor Accelerated Testing (PCAT) Facility was built at ORNL for testing overhead conductors. The PCAT has been uniquely designed for testing overhead bare transmission line conductors at high currents and temperatures after they have been installed and tensioned to the manufacturer's specifications. The ability to operate a transmission line conductor in this manner does not exist elsewhere in the United States. Four classes of ACCR cable designed by the 3M Company have been successfully test at ORNL small, medium, large and small/compact. Based on these and other manufacturer tests, the 3M Company has successfully introduced the ACCR into the commercial market and has completed over twenty installations for utility companies.

  13. GAM observation in the TUMAN-3M tokamak

    Bulanin, V. V.; Askinazi, L. G.; Belokurov, A. A.; Kornev, V. A.; Lebedev, V.; Petrov, A. V.; Tukachinsky, A. S.; Vildjunas, M. I.; Wagner, F.; Yashin, A. Yu

    2016-04-01

    Results of an experimental study of geodesic acoustic modes (GAM) in the TUMAN-3M tokamak are reported. With Doppler backscattering (DBS) the basic properties of the GAM such as frequency, conditions for the GAM existence and the GAM radial location have been identified. The two-frequency Doppler reflectometer system was employed to reveal an interplay between low frequency sheared poloidal rotation, ambient turbulence level and the GAM intensity. Bicoherence analysis of the DBS data evidences the presence of a nonlinear interaction between the GAM and plasma turbulence.

  14. Hamline/3M Corp. Project: Liason for Curricular Change*

    Artz, Jerry L.

    2002-04-01

    This project was designed to catalyze curricular changes to better prepare students for the workplace. Industrial managers provided a list of 16 characteristics valued in the workplace; most were NOT related to science course content. The project formed 5 teams each including 3M professionals and students. Each team developed curricular changes in one of the 16 areas. Team goals were to improve skills in communication, data analysis, business/economics, team problem solving, and cultural competency. Curricular changes realized include communication skill activities embodied in science courses and faculty communication teaching skill seminars; self learning tools in data analysis, statistics and model building; a new course developed with assistance from 3M personnel focusing on topics directly related to technological industries; high performance team problem solving training/coaching for faculty; workshops for students and faculty relative to importance of cultural competencies in the workplace; and a new course focusing on culture, team problem solving and conflict resolution in the technical workplace. Process for developing and content of curricular changes will be reported. *Thanks to: NSF GOALI CHE-99010782

  15. Hamline/3M Project: Liaison for Curricular Change

    Rundquist, Andy

    2002-03-01

    This project was designed to catalyze curricular changes to better prepare students for the workplace. Industrial managers provided a list of 16 characteristics valued in the workplace: most were NOT related to science course content. The project formed 5 teams each including 3M professionals and students. Each team developed curricular changes in one of the 16 areas. Team goals were to improve skills in communication, data analysis, business/economics, team problem solving, and culture competency. Curricular changes realized include communication skill activities embodied in science courses and faculty communication teaching skill seminars, self learning tools in data analysis, statistics and model building, a new course developed with assistance from 3M personnel focussing on topics directly related to technological industries, high performance team problem solving training/coaching for faculty and workshops for students and faculty relative to importance of cultural competencies in the workplace, and a new course focusing on culture, team problem solving and conflict resolution in the technical workplace. Process for developing and content of curricular changes will be reported.

  16. Alloying behavior of Ni3M-type GCP compounds

    The site preference of ternary additions in Ni3M-type GCP compounds was determined from the direction of solubility lobe of the GCP phase on the ternary phase diagram that have been experimentally reported. In Ni3Nb (D0a), Co and Cu preferred the substitution for Ni-site, Ti, V and W the substitution for Nb-site, and Fe the substitution for both sites. In Ni3V (D022), Co preferred the substitution for Ni-site, Cr the substitution for both sites, and Ti the substitution for V-site. In Ni3Ti (D024), Fe, Co, Cu, and Si preferred the substitution for Ni-site, Nb, Mo and V the substitution for Ti-site. The thermodynamic model, which was based on the change in total bonding energy of the host compound by a small addition of ternary solute, was applied to predict the site preference of ternary additions. The bond energy of each nearest neighbor pair used in the thermodynamic calculation was derived from the heat of compound formation by Miedema's formula. The agreement between the thermodynamic model and the result of the literature search was excellent. From both experimental and theoretical results, it was shown in three Ni3M-type GCP compounds that both transition and B-subgroup elements have two possibilities, i.e., the case of substitution for Ni-site or the case for M-site, depending on the relative value of two interaction energies.

  17. 3m vacuum ultraviolet spectrometer with optical multichanel detector

    This paper, describes the design and the performance of a normal incidence vacuum ultraviolet spectrometer, for the 300-2400 A spectral range. It is provided with a multichannel detection system. The monochromator is original design and it has been built at CIEMAT: It is equipped with a 3 m concave holographic grating with 2400 grooves/mm. The multichannel detector consists of a windowless double microchannel plate/phosphor screen image intensifier, coupled by fiber optic to a 1024 elements self-scanning linear photodiode array. The output from the arrays is digitized by a 12-bit analog to digital converter and stored in a computer for its later analysis. The necessary software to store and display data has been developed. (Author)

  18. Testing of the 3M Company ACCR Conductor

    Stovall, J.P.; RIzy, D.T.; Kisner, R.A.; Deve, H.E. (3M Comp.)

    2010-09-15

    The 3M Company has developed a high-temperature low-sag conductor referred to as Aluminum- Conductor Composite-Reinforced or ACCR. The conductor uses an aluminum metal matrix material to replace the steel in conventional conductors so the core has a lower density and higher conductivity. The objective of this work is to accelerate the commercial acceptance by electric utilities of these new conductor designs by testing four representative conductor classes in controlled conditions. Overhead transmission lines use bare aluminum conductor strands wrapped around a steel core strands to transmit electricity. The typical cable is referred to as aluminum-conductor steel-reinforced (ACSR). The outer strands are aluminum, chosen for its conductivity, low weight, and low cost. The center strand is of steel for the strength required to support the weight without stretching the aluminum due to its ductility. The power density of a transmission corridor has been directly increased by increasing the voltage level. Transmission voltages have increased from 115-kV to 765- kV over the past 80 years. In the United States, further increasing the voltage level is not feasible at this point in time, so in order to further increase the power density of a transmission corridor, conductor designs that increase the current carrying capability have been examined. One of the key limiting factors in the design of a transmission line is the conductor sag which determines the clearance of the conductor above ground or underlying structures needed for electrical safety. Increasing the current carrying capability of a conductor increases the joule heating in the conductor which increases the conductor sag. A conductor designed for high-temperature and lowsag operation requires an engineered modification of the conductor materials. To make an advanced cable, the 3M Company solution has been the development of a composite conductor consisting of Nextel ceramic fibers to replace the steel core and

  19. 3m Vacuum Ultraviolet Spectrometer with Optical Multichannel Detector

    This paper describes the design and the performance of a normal incidence vacuum ultraviolet spectrometer, for the 300-2400 A spectral range. It is provided with a multichannel detection system. The monochromator is original design and it has been built at CIEMAT. It is equipped with a 3 m concave holographic grating with 2400 grooves/mm. The multichannel detector consists of a windowless double microchannel plate / phosphor screen image intensifier, coupled by fiber optic to a 1024 elements self-scanning linear photodiode array. The output from the array is digitized by a 12-bit analog to digital converter and stored in a computer, for its later analysis. The necessary software to store and display data has been developed. (Author) 18 refs

  20. The High Resolution Neutron Powder Diffractometer at JRR-3M

    Characteristics of the High Resolution Neutron Powder Diffractometer (HRPD) installed and studied recently at the JRR-3M are reported. The HRPD is an ILL-D2B type diffractometer and has features such as a fine collimation system: 6' - 20' - 6', two high take-off angles of monochromator and sixty four 3rd-collimator and detector systems placed at every 2.5 degree of diffraction angle. Typical diffraction pattern can be taken an the scattering angle from 5 to 160 degrees in about several hours depending on the sample material, and analyzed by the Rietveld profile refinement method or others. The best resolution is 0.2 degree at the focusing position which corresponds to 0.2 % in Δd/d. In a series of study of the high Tc superconductors, La2NiO4.00 was investigated between 610K and 6K. The crystal structure below 60K was determined to be orthorhombic and the magnetic moment of Ni2+ was evaluated to be about 1.5 μB at 80K and 1.7 μB at 6K through a Rietveld analysis. (author)

  1. Modification of the Simpson moduli space M_{3m+1}(P_2) by vector bundles (I)

    Iena, Oleksandr

    2010-01-01

    We consider the moduli space of stable vector bundles on curves embedded in P_2 with Hilbert polynomial 3m+1 and construct a compactification of this space by vector bundles. The result is a blow up of the Simpson moduli space M_{3m+1}(P_2).

  2. 3M3200型高效防尘口罩佩戴试验应用%3M3200 -efficiency dust masks to wear test application

    周和军

    2011-01-01

    为了做好煤矿职业危害作业场所防护,杜绝煤矿职业尘肺病发病率,提升职工个体防护用品,分三个月时间在协庄煤矿、翟镇煤矿两矿进行了3M3200型高效防尘口罩全员佩戴试验,通过抽样调查得出结论:3M3200型高效防尘口罩具有阻垂效果好、体积小、重量轻、佩戴方便等特点,可以推广应用。%In order to make coal workplace occupational hazard protection, to prevent the incidence of pneumoconiosis Oeupational , improve employee personal protection products, sub - three months in the co - Mine, Mine Zhaizhen coal were the two high - efficiency dust masks, 3M 3200 full wear test', a sample survey concluded by : 3 M 3200 High - efficiency dust masks, dust with effective resistance, small size, light weight, convenient to wear, can be popularized.

  3. Digital signage sobre IP

    Casademont Filella, Albert

    2012-01-01

    Projecte que versa sobre el disseny i la implementació d'un sistema de Digital Signage (Cartelleria Digital) sobre IP, creant un gestor que permeti controlar de forma remota tot un conjunt de petits dispositius connectats a pantalles que emeten continguts multimèdia com vídeos, imatges, feeds rss...

  4. CRM System Using PA-AKD Approach of D3M

    Ajay kumar

    2010-04-01

    Full Text Available In today’s business world, Customer Relationship Management has become conventional. Inspite of the unpredictable economy, CRM is being forced into corporate budgets and is believed to be the leading and initiative factor by many companies. The custom of CRM system has become mandatory. An adequate CRM system helps in acquiring new customers and increasing the value of existing customers. Datawarehouse acts as the data resource for D3M on CRM. This paper introduces the CRM based on PA-AKD and managing relationships with customers which has become the critical competition betweenorganizations. Then the structure of CRM is described with the help of D3M, discusses the procedure to Data warehouse and the significance of D3M applied to CRM. At the end, the promoting effects of D3M to individual service are presented

  5. Pengaruh Penerapan Sistem Informasi Akuntansi Terhadap Pengambilan Keputusan Pada Politeknik Unggul LP3M Medan

    Nasir, Miftah Faridh

    2014-01-01

    The purpose of this study was to determine how the analysis of the application of information systems in the management accounting can affect decision-making at the Polytechnic Unggul LP3M Medan and to determine the accounting information system to ensure accurate decision-making in a company. Primary data were collected by interviewing management and data documenting the Polytechnic Superior LP3M Medan. The analytical method used is descriptive. Hypothesis in this study is a significa...

  6. Minimum core configuration with IRT-3M fuel in the VR-1 reactor

    The present paper shortly describes advances of the RERTR program in the Czech Republic. The minimum core configuration B2 with 9 fuel elements IRT-3M and Beryllium reflector was performed on the training reactor VR-1 Sparrow. The paper presents results of reactor calculations and experimental measurements on the core configuration B2, their evaluation as well as the operation experiences with the Russian fuel assemblies IRT-3M on the reactor VR-1. (author)

  7. Ultrafiltros sobre ω.

    Mancilla Hernández, Salvador

    2012-01-01

    El objetivo del presente trabajo estudiar los ideales y filtros sobre conjuntos numerables, los que comúnmente conocemos como filtros sobre ω o ideales sobre ω. Dentro de estos, nos enfocaremos en la clase de I-ultrafiltros los cuales fueron estudiados por James Baumgartner en [11]. Y dentro de esta clase de ultrafiltros, nos concentraremos cuando I es {A ⊆ ω : n∈A g(n) < ∞}, también conocido como ideal sumable con respecto a g, donde g es una sucesión de números reales no negativ...

  8. Sobre el Paisaje Cultural

    Hernández León, Juan Miguel

    2008-01-01

    El 4º Congreso Europeo sobre Investigación Arquitectónica y Urbana EURAU’08, organizado por la Escuela Técnica Superior de Arquitectura de la Universidad Politécnica de Madrid y dedicado a reflexionar sobre el “Paisaje cultural”, continúa la tarea de intercambio de conocimientos científicos y experiencias docentes entre las escuelas y facultades europeas de Arquitectura emprendida en las ediciones anteriores de Marsella, acerca de “La cuestión doctoral”, de Lille, sobre “El espacio considerad...

  9. Syntheses, structures, optical properties, and electronic structures of KBaMSe3 (M = As, Sb)

    Graphical abstract: KBaMSe3 (M = As, Sb) are isostructural and crystallize in the centrosymmetric monoclinic space group P21/c with zero-dimensional structures containing totally isolated MSe3 (M = As, Sb) pyramids with K+ and Ba2+ cations lying between them. - Highlights: • Two new quaternary chalcogenides KBaMSe3 (M = As, Sb) were synthesized. • They are isostructural and crystallize in the centrosymmetric space group P21/c. • They adopt a zero-dimensional structure containing isolated MSe3 trigonal pyramids. • The optical band gaps are 2.26 (2) eV for KBaAsSe3 and 2.04 (2) eV for KBaSbSe3. • KBaMSe3 (M = As, Sb) are indirect band gap semiconductors. - Abstract: The first two members in the quaternary A/A′/M/Q (A = alkali metal; A′ = alkaline-earth metal; M = As, Sb, Bi; Q = S, Se, Te) system, namely the KBaMSe3 (M = As, Sb) selenides, have been synthesized by solid state reactions. They are isostructural and crystallize in the centrosymmetric space group P21/c of the monoclinic system. In the structure, the trivalent M atom (M = As, Sb) is coordinated to three Se atoms forming a trigonal pyramid with the Se atoms serving as the triangle base, showing the stereochemical activity of the ns2 lone pair electron. The MSe3 (M = As, Sb) trigonal pyramids are totally isolated from each other with K+ and Ba2+ cations located between them. The optical band gaps of 2.26 (2) eV for KBaAsSe3 and 2.04 (2) eV for KBaSbSe3, were deduced from the diffuse reflectance spectra. The first principles calculations were performed to study the electronic structures of KBaMSe3 (M = As, Sb) compounds and the results indicated that these two compounds are indirect band gap semiconductors

  10. 3M Tecra Listeria Visual Immunoassay: AOAC Official Methods 995.22 and 2002.09.

    Benesh, Deann L; Crowley, Erin S; Bird, Patrick M

    2013-01-01

    A validation study of the 3M Tecra Listeria Visual Immunoassay (VIA; 3M Food Safety, St. Paul, MN) was conducted at Q Laboratories, Inc., Cincinnati, OH. The 3M Tecra Listeria VIA method was compared to the Health Canada MFHPB-30 reference method for the analysis of five ready-to-eat (RTE) meats: deli turkey, hot dogs, liver pate, raw fermented sausage, and deli ham, and on a stainless steel environmental surface. Twenty replicates of each of the five food matrixes were analyzed at a low and a high inoculum level. The low-level test portions were inoculated with 0.2-2 CFU/25 g, and the high-level test portions with 2-5 CFU/25 g. In addition, 20 replicates of one environmental surface were analyzed at a low and a high inoculum level. The low-level sampling area was inoculated with 0.2-2 CFU/5 cm2, and the high-level area with 2-5 CFU/5 cm2. Five control replicates were also analyzed at 0 CFU/25 g (uninoculated) for the foods and at 0 CFU/5 cm2 for the environmental sampling area. There was no significant difference in the number of positives detected by the 3M Tecra Listeria VIA and the Health Canada MFHPB-30 reference method for four of the RTE meats and the stainless steel environmental surface analyzed in this study. For the raw, fermented sausage, there was a significant difference in the number of positives detected for the high inoculum level by the 3M Tecra Listeria VIA and the Health Canada MFHPB-30 reference method, with the 3M Tecra Listeria VIA method detecting more positives. PMID:23767342

  11. Creation of low density starting plasma with small frame antenna at Uragan-3M device

    Deficient shot-to-shot stability of Uragan-3M discharges makes difficult to reproduce experimental results over the period of experimental session. An efficient way of reducing difference between shots is creation of initial low density plasma before the main discharge to start up. A RF pre-ionization in the same frequency range as that of the main discharge is used in the Uragan-3M torsatron. The pre-ionization provides stable discharges during the whole experimental campaign. The main parameters of the pre-ionization plasma are measured and discussed

  12. Marketingová strategie hasících kapalin Novec firmy 3M

    Peřina, Matěj

    2012-01-01

    This thesis is concerned with B2B market segmentation, situational analysis and proposes a markting strategy for Novec 1230 fire protection fluid marketed by 3M Česko. Firstly a marketing literature rewiev is carried out in order to uncover the most suitabe theoretical approaches to the subject at hand. Then the 3M Company and its Czech subsidiary are presented. In the methodological part there is a description of utilized methods and approaches. Data colection and analysis are executed in th...

  13. Automatizacija praćenja rada relativnih gravimetara Scintrex Autograv CG-3M

    Repanić, Marija

    2013-01-01

    U radu je prikazano automatizirano praćenje rada relativnih gravimetara Scintrex Autograv CG-3M primjenom aplikacije Pragra, izrađene u programskom paketu MATLAB. Scintrex Autograv CG-3M je moderni relativni gravimetar. Nakon postavljanja gravimetra na točku, horizontiranja i pokretanja mjerenja, mjerni proces je potpuno automatiziran. Mjerni signal se već u gravimetru, na temelju definirane kalibracijske funkcije, pretvara u očitanja ubrzanja sile teže na koje se primjenjuju instrumentalne k...

  14. 3m Vacuum Ultraviolet Spectrometer with Optical Multichannel Detector; Espectrometro de ultravioleta de vacio de 3m provisto de sistema de deteccion optical multicanal

    Martin, P.; Peraza, C.; Blanco, F.; Campos, J.

    1993-07-01

    This paper describes the design and the performance of a normal incidence vacuum ultraviolet spectrometer, for the 300-2400 A spectral range. It is provided with a multichannel detection system. The monochromator is original design and it has been built at CIEMAT. It is equipped with a 3 m concave holographic grating with 2400 grooves/mm. The multichannel detector consists of a windowless double microchannel plate / phosphor screen image intensifier, coupled by fiber optic to a 1024 elements self-scanning linear photodiode array. The output from the array is digitized by a 12-bit analog to digital converter and stored in a computer, for its later analysis. The necessary software to store and display data has been developed. (Author) 18 refs.

  15. Efficient use of electric power in corporative 3M Mexico; Uso eficiente de la energia electrica en el corporativo 3M Mexico

    Sanchez Perez, Alfredo; Quinones Bonilla, Antonio S. [3M Mexico, S.A. de C.V. (Mexico); Bustos Antunez, Jorge I.; Reyes Arce, Manuel [Hines Interests, S.A. de C.V. (Mexico)

    2003-07-01

    It is not enough to count on with the state of the art technology for the daily operation of a building, the challenge is to be able to make a clear analysis and with attainable goals for the optimization of rational use of the electrical energy in the operation of intelligent buildings without affecting the comfort and productivity for users as well as the functionality and profitability for the owner. This went our base to carry out control strategies that helped the efficient use of the electrical energy, obtaining important savings without neglecting the operative part, of services and human within the property. It is thus, that 3M Mexico wanting to reach these purposes, conducted actions to improve the efficiency of the equipment in the following items: electric network, general lighting, air conditioning system, ventilation and extraction, hydropneumatic system, and sumps operation. [Spanish] No basta contar con la tecnologia de punta para la operacion diaria de un edificio, el reto es ser capaces de realizar un analisis claro y con metas alcanzables para la optimizacion de uso racional de la energia electrica en las operaciones de edificios inteligentes sin afectar el confort y productividad para usuarios asi como la funcionalidad y rentabilidad para el propietario. Esta fue nuestra base para llevar a cabo estrategias de control que ayudaron al uso eficiente de la energia electrica, obteniendo ahorros importantes sin descuidar la parte operativa, de servicios y humana dentro de la propiedad. Es asi, que 3M Mexico queriendo alcanzar dichos propositos, realizo acciones para mejorar la eficiencia de los equipos en los siguientes rubros: red electrica, iluminacion general, sistema de aire acondicionado, ventilacion y extraccion, sistema hidroneumatico, y operacion de carcamos.

  16. A DS106 Thing Happened on the Way to the 3M Tech Forum

    Lockridge, Rochelle; Levine, Alan; Funes, Mariana

    2014-01-01

    This case study illustrates how DS106, a computer science course in Digital Storytelling from the University of Mary Washington (UMW) and accessible as an open course on the web, is being explored in a corporate environment at 3M, an American multinational corporation based in St. Paul, Minnesota, to build community, collaboration, and more…

  17. CRM System Using CM-AKD Approach of D3M

    I.Kali Pradeep,

    2010-03-01

    Full Text Available In the present days, the Customer Relationship Management (CRM for short system has entered into the mainstream despite the uncertainty of the economy. CRM is being trust into corporate budgets and talked about as a critical initiative by various companies. CRM is an important edge in the business world. Building an effective CRM system can get more effectively in acquiring new customers, increasing value of existing customers and retaining good customers. At the same time, the data and data warehouse will offer the best dataresource for the application of Domain Drive Data Mining (D3M for short on CRM. The managing relationships with the customer have become a critical organizational competency. In this paper we introduce CRM with the advanced technologies for getting winning strategies. Later on, we introduce the architecture of CRM based on D3M. Which involves in designing the main steps of data warehouse and also it describes the managing of D3M applied to CRM. Finally, the promoting effects of D3M to individual services are presented.

  18. Study of neutron medical irradiation facility with supermirror neutron guide tube in JRR-3M

    A medical irradiation facility using a supermirror guide tube has been designed for boron neutron capture therapy (BNCT) treatment at the JRR-3M. Intense thermal neutrons are obtained with lower fast neutrons and gamma rays contamination at the end of neutron guide tube. It would be a most suitable neutron field for BNCT treatment. (author)

  19. Syntheses, structures, optical properties, and electronic structures of KBaMSe{sub 3} (M = As, Sb)

    Yin, Wenlong [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-306 Mianyang 621900 (China); Feng, Kai; Kang, Lei [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); University of the Chinese Academy of Sciences, Beijing 100049 (China); Kang, Bin; Deng, Jianguo [Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-306 Mianyang 621900 (China); Lin, Zheshuai [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Yao, Jiyong, E-mail: jyao@mail.ipc.ac.cn [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Wu, Yicheng [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-12-25

    Graphical abstract: KBaMSe{sub 3} (M = As, Sb) are isostructural and crystallize in the centrosymmetric monoclinic space group P2{sub 1}/c with zero-dimensional structures containing totally isolated MSe{sub 3} (M = As, Sb) pyramids with K{sup +} and Ba{sup 2+} cations lying between them. - Highlights: • Two new quaternary chalcogenides KBaMSe{sub 3} (M = As, Sb) were synthesized. • They are isostructural and crystallize in the centrosymmetric space group P2{sub 1}/c. • They adopt a zero-dimensional structure containing isolated MSe{sub 3} trigonal pyramids. • The optical band gaps are 2.26 (2) eV for KBaAsSe{sub 3} and 2.04 (2) eV for KBaSbSe{sub 3}. • KBaMSe{sub 3} (M = As, Sb) are indirect band gap semiconductors. - Abstract: The first two members in the quaternary A/A′/M/Q (A = alkali metal; A′ = alkaline-earth metal; M = As, Sb, Bi; Q = S, Se, Te) system, namely the KBaMSe{sub 3} (M = As, Sb) selenides, have been synthesized by solid state reactions. They are isostructural and crystallize in the centrosymmetric space group P2{sub 1}/c of the monoclinic system. In the structure, the trivalent M atom (M = As, Sb) is coordinated to three Se atoms forming a trigonal pyramid with the Se atoms serving as the triangle base, showing the stereochemical activity of the ns{sup 2} lone pair electron. The MSe{sub 3} (M = As, Sb) trigonal pyramids are totally isolated from each other with K{sup +} and Ba{sup 2+} cations located between them. The optical band gaps of 2.26 (2) eV for KBaAsSe{sub 3} and 2.04 (2) eV for KBaSbSe{sub 3}, were deduced from the diffuse reflectance spectra. The first principles calculations were performed to study the electronic structures of KBaMSe{sub 3} (M = As, Sb) compounds and the results indicated that these two compounds are indirect band gap semiconductors.

  20. miR-155 targets Caspase-3 mRNA in activated macrophages.

    De Santis, Rebecca; Liepelt, Anke; Mossanen, Jana C; Dueck, Anne; Simons, Nadine; Mohs, Antje; Trautwein, Christian; Meister, Gunter; Marx, Gernot; Ostareck-Lederer, Antje; Ostareck, Dirk H

    2016-01-01

    To secure the functionality of activated macrophages in the innate immune response, efficient life span control is required. Recognition of bacterial lipopolysaccharides (LPS) by toll-like receptor 4 (TLR4) induces downstream signaling pathways, which merge to induce the expression of cytokine genes and anti-apoptotic genes. MicroRNAs (miRNAs) have emerged as important inflammatory response modulators, but information about their functional impact on apoptosis is scarce. To identify miRNAs differentially expressed in response to LPS, cDNA libraries from untreated and LPS-activated murine macrophages were analyzed by deep sequencing and regulated miRNA expression was verified by Northern blotting and qPCR. Employing TargetScan(TM) we identified CASPASE-3 (CASP-3) mRNA that encodes a key player in apoptosis as potential target of LPS-induced miR-155. LPS-dependent primary macrophage activation revealed TLR4-mediated enhancement of miR-155 expression and CASP-3 mRNA reduction. Endogenous CASP-3 and cleaved CASP-3 protein declined in LPS-activated macrophages. Accumulation of miR-155 and CASP-3 mRNA in miRNA-induced silencing complexes (miRISC) was demonstrated by ARGONAUTE 2 (AGO2) immunoprecipitation. Importantly, specific antagomir transfection effectively reduced mature miR-155 and resulted in significantly elevated CASP-3 mRNA levels in activated macrophages. In vitro translation assays demonstrated that the target site in the CASP-3 mRNA 3'UTR mediates miR-155-dependent Luciferase reporter mRNA destabilization. Strikingly, Annexin V staining of macrophages transfected with antagomir-155 and stimulated with LPS prior to staurosporine (SSP) treatment implied that LPS-induced miR-155 prevents apoptosis through CASP-3 mRNA down-regulation. In conclusion, we report that miR-155-mediated CASP-3 mRNA destabilization in LPS-activated RAW 264.7 macrophages suppresses apoptosis, as a prerequisite to maintain their crucial function in inflammation. PMID:26574931

  1. Assessment of zenith tropospheric delay derived from UNB3m model over Asia area

    Huang, Liangke; Xie, Shaofeng; Liu, Lilong; Feng, Haiyang; Jiang, Maofang

    2015-12-01

    The tropospheric delay is one of the main errors for earth observation and a variety of radio navigation technologies, and the UNB3m model can be used to calculate the zenith tropospheric delay (ZTD) without any real measured meteorological data, which taking the major changes in water vapor profiles with latitude into account, and it widely applied in Wide Area Augmentation System in America. However, there are few researches carried out on the assessment of ZTD from UNB3m model over Asia area. In this study, three years of the ZTD data observed from 56 IGS (International GNSS service) sites distributed in Asia area is used to assess the effectiveness and accuracy of ZTD calculated from UNB3m model. The results are: (1) relative to IGS observed ZTD, the bias and root mean square (RMS) for ZTD calculated from UNB3m model are -0.1 cm and 6.0 cm, respectively. Besides, the bias shows significant periodic characteristics in Asia area. (2) The bias and RMS present seasonal variations, which generally show larger values in summer months. (3) The precision of ZTD calculated from UNB3m model increases with increasing altitude or latitude, and also the bias and RMS show inconsistently in different Asia areas. At last, the best results can be achieved in inland area where presents the mean yearly RMS of 2.4 cm. These results provide a reference for the study of the tropospheric delay correction model and the applications of real-time GNSS navigation and positioning.

  2. Inferencias sobre Grafos

    Sira M. Allende; Carlos N. Bouza

    2002-01-01

    El estudio de un juego puede ser modelado asumiendo que solo algunas partidas son observadas. Entonces el árbol del juego debe ser estimado utilizando información muestral. Similarmente ocurre al obtener información sobre el comportamiento de las decisiones tomadas por individuos muestreados sobre un árbol de decisión teórico. Al considerar una medida de probabilidad que caracterice el comportamiento de redes aleatorias se puede obtener un estimado del árbol asociado. Este problema es el anal...

  3. Mitos sobre agroecologia.

    Canuto, João Carlos

    2011-01-01

    O presente ensaio vem a discutir alguns aspectos do discurso sobre a Agroecologia, procurando evidenciar contradições do senso comum, advindas seja de parte da comunidade leiga, dos meios de comunicação ou da comunidade científica. Coloca em debate alguns mitos sobre os sistemas agroecológicos, tais como: que sejam tecnologicamente retrógrados, de baixa produtividade, exigentes em mão-de-obra, economicamente inviáveis e “puramente ideológicos”.

  4. How to convert SPME into P3M. Lattice green functions and error estimates

    Complete text of publication follows. Particle-Mesh methods, such as Particle-Particle Particle-Mesh (P3M) and Smooth Particle Mesh Ewald (SPME), are efficient methods to compute long-range Coulomb (or gravitational) forces in simulations of many-particle systems. These methods reduce the complexity of computing O(N2) pairwise interactions into an O(N logN) problem by discretizing the charge density onto a mesh and by using Fast-Fourier-Transforms to calculate the electrostatic potential. Several variants of particle-mesh methods exist, characterized by different choices for some ingredients, in particular the charge assignment function used to map the particles onto the mesh, the lattice Green function used in the computation of the electrostatic potential, and the differentiation scheme used to calculate forces from the mesh-based potential. The accuracy of particle-mesh methods can also be enhanced by using mesh interlacing (or staggering). In the SPME method, forces are computed for example by using the analytical differentiation (AD) scheme, which uses the exact gradient of the charge assignment function, while forces are usually computed in a P3M algorithm by using finite differences, or by differentiating the potential in reciprocal space (multiplication by i∼k). The accuracy of the P3M method has been studied in depths using Fourier and signal analysis methods. That analysis allowed to optimize the accuracy of the P3M method via the use of an error minimizing lattice Green function, and also to have full control over the accuracy of the method thanks to an a priori error estimate. In this work, we show that a similar analysis can also be applied to the commonly used SPME method. This enables to convert straightforwardly an SPME method into the corresponding P3M method, which allows to improve slightly the accuracy of the algorithm by using the optimized P3M lattice Green function. As a by-product, that analysis yields also an a priori error estimate for

  5. Relevance of the ligand exchange rate and mechanism of fac-[(CO)3M(H2O)3]+ (M = Mn, Tc, Re) complexes for new radiopharmaceuticals.

    Grundler, Pascal V; Helm, Lothar; Alberto, Roger; Merbach, André E

    2006-12-11

    The water exchange process on fac-[(CO)3Mn(H2O)3]+ and fac-[(CO)3Tc(H2O)3]+ was kinetically investigated by 17O NMR as a function of the acidity, temperature, and pressure. Up to pH 6.3 and 4.4, respectively, the exchange rate is not affected by the acidity, thus demonstrating that the contribution of the monohydroxo species fac-[(CO)3M(OH)(H2O)2] is not significant, which correlates well with a higher pKa for these complexes compared to the homologue fac-[(CO)3Re(H2O)3]+ complex. The water exchange rate K298ex/s(-1) (DeltaHex double dagger/kJ mol(-1); DeltaSex double dagger/J mol(-1) K(-1); DeltaV double dagger/cm3 mol-1) decreases down group 7 from Mn to Tc and Re: 23 (72.5; +24.4; +7.1) > 0.49 (78.3; +11.7; +3.8) > 5.4 x 10(-3) (90.3; +14.5; -). For the Mn complex only, an O exchange on the carbonyl ligand could be measured (K338co = 4.3 x 10(-6) s(-1)), which is several orders of magnitude slower than the water exchange. In the case of the Tc complex, the coupling between 17O (I = 5/2) and 99Tc (I = 9/2) nuclear spins has been observed (1J99Tc,17O = 80 +/- 5 Hz). The substitution of water in fac-[(CO)3M(H2O)3]+ by dimethyl sulfide (DMS) is slightly faster than that by CH3CN: 3 times faster for Mn, 1.5 times faster for Tc, and 1.2 times faster for Re. The pressure dependence behavior is different for Mn and Re. For Mn, the change in volume to reach the transition state is always clearly positive (water exchange, CH3CN, DMS), indicating an Id mechanism. In the case of Re, an Id/Ia changeover is assigned on the basis of reaction profiles with a strong volume maximum for pyrazine and a minimum for DMS as the entering ligand. PMID:17140248

  6. Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

    Omofoye Oluwaseun

    2008-05-01

    Full Text Available Abstract Background IGF binding protein-3 (IGFBP-3 regulates the bioavailability of insulin-like growth factors I and II, and has both anti-proliferative and pro-apoptotic properties. Elevated plasma IGFBP-3 has been associated with reduced risk of colorectal cancer (CRC, but the role of tissue IGFBP-3 is not well defined. We evaluated the association between tissue or plasma IGFBP-3 and risk of colorectal adenomas or low apoptosis. Methods Subjects were consenting patients who underwent a clinically indicated colonoscopy at UNC Hospitals and provided information on diet and lifestyle. IGFBP-3 mRNA in normal colon was assessed by real time RT-PCR. Plasma IGFBP-3 was measured by ELISA and apoptosis was determined by morphology on H & E slides. Logistic regression was used to compute odds ratio (OR and 95% confidence intervals. Results We observed a modest correlation between plasma IGFBP-3 and tissue IGFBP-3 expression (p = 0.007. There was no significant association between plasma IGFBP-3 and adenomas or apoptosis. Tissue IGFBP-3 mRNA expression was significantly lower in cases than controls. Subjects in the lowest three quartiles of tissue IGFBP-3 gene expression were more likely to have adenomas. Consistent with previous reports, low apoptosis was significantly associated with increased risk of adenomas (p = 0.003. Surprisingly, local IGFBP-3 mRNA expression was inversely associated with apoptosis. Conclusion Low expression of IGFBP-3 mRNA in normal colonic mucosa predicts increased risk of adenomas. Our findings suggest that local IGFBP-3 in the colon may directly increase adenoma risk but IGFBP-3 may act through a pathway other than apoptosis to influence adenoma risk.

  7. IGFBP3 mRNA expression in benign and malignant breast tumors

    Ren, Zefang; Shin, Aesun; Cai, Qiuyin; Shu, Xiao-Ou; Gao, Yu-Tang; Zheng, Wei

    2007-01-01

    Introduction Most previous studies have focused on evaluating the association between circulating insulin-like growth factor binding protein 3 (IGFBP-3) levels and breast cancer risk. Emerging evidence over the past few years suggests that IGFBP-3 may act directly on mammary epithelial cells. Methods To understand the role of IGFBP-3 in breast tumorigenesis, we investigated IGFBP3 mRNA expression levels in benign and malignant breast tumors and their adjacent normal tissues using real-time qu...

  8. El servicio edición digital en la UC3M

    Aguilera Ortega, Raúl; Sotoca, Blanca

    2009-01-01

    En esta comunicación se presenta el Servicio de Edición Digital (SED) de la Universidad Carlos III de Madrid. SED es el encargado de gestionar la producción y difusión de ediciones digitales, bajo demanda, de revistas y libros generados en el transcurso de la actividad científica y de investigación de los miembros de la Comunidad Universitaria de la UC3M.

  9. Modified Foxp3 mRNA protects against asthma through an IL-10 dependent mechanism

    Mays, Lauren E.; Ammon-Treiber, Susanne; Mothes, Benedikt; Alkhaled, Mohammed; Rottenberger, Jennifer; Müller-Hermelink, Eva Sophie; Grimm, Melanie; Mezger, Markus; Beer-Hammer, Sandra; von Stebut, Esther; Rieber, Nikolaus; Nürnberg, Bernd; Schwab, Matthias; Handgretinger, Rupert; Idzko, Marco

    2013-01-01

    Chemically modified mRNA is capable of inducing therapeutic levels of protein expression while circumventing the threat of genomic integration often associated with viral vectors. We utilized this novel therapeutic tool to express the regulatory T cell transcription factor, FOXP3, in a time- and site-specific fashion in murine lung, in order to prevent allergic asthma in vivo. We show that modified Foxp3 mRNA rebalanced pulmonary T helper cell responses and protected from allergen-induced tis...

  10. Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

    IGF binding protein-3 (IGFBP-3) regulates the bioavailability of insulin-like growth factors I and II, and has both anti-proliferative and pro-apoptotic properties. Elevated plasma IGFBP-3 has been associated with reduced risk of colorectal cancer (CRC), but the role of tissue IGFBP-3 is not well defined. We evaluated the association between tissue or plasma IGFBP-3 and risk of colorectal adenomas or low apoptosis. Subjects were consenting patients who underwent a clinically indicated colonoscopy at UNC Hospitals and provided information on diet and lifestyle. IGFBP-3 mRNA in normal colon was assessed by real time RT-PCR. Plasma IGFBP-3 was measured by ELISA and apoptosis was determined by morphology on H & E slides. Logistic regression was used to compute odds ratio (OR) and 95% confidence intervals. We observed a modest correlation between plasma IGFBP-3 and tissue IGFBP-3 expression (p = 0.007). There was no significant association between plasma IGFBP-3 and adenomas or apoptosis. Tissue IGFBP-3 mRNA expression was significantly lower in cases than controls. Subjects in the lowest three quartiles of tissue IGFBP-3 gene expression were more likely to have adenomas. Consistent with previous reports, low apoptosis was significantly associated with increased risk of adenomas (p = 0.003). Surprisingly, local IGFBP-3 mRNA expression was inversely associated with apoptosis. Low expression of IGFBP-3 mRNA in normal colonic mucosa predicts increased risk of adenomas. Our findings suggest that local IGFBP-3 in the colon may directly increase adenoma risk but IGFBP-3 may act through a pathway other than apoptosis to influence adenoma risk

  11. Ultra Barrier Topsheet Film for Flexible Photovoltaics with 3M Company

    Funkenbusch, Arnold W. [3M Company, Saint Paul, MN (United States); Charles, Ruth P. [3M Company, Saint Paul, MN (United States)

    2014-12-30

    In this DOE sponsored program, 3M achieved the critical UBT features to enable durable flexible high efficiency modules to be produced by a range of customers who have now certified the 3M UBT and are actively developing said flexible modules. The specific objectives and accomplishments of the work under this program were; Scale-up the current Generation-1 UBT from 12” width, as made on 3M’s pilot line, to 1+meter width full-scale manufacturing, while maintaining baseline performance metrics (see table below); This objective was fully met; Validate service life of Generation-1 UBT for the 25+ year lifetime demanded by the photovoltaic market; Aggressive testing revealed potential failure modes in the Gen 1 UBT. Deficiencies were identified and corrective action taken in the Gen 2 UBT; Develop a Generation-2 UBT on the pilot line, targeting improved performance relative to baseline, including higher %T (percent transmission), lower water vapor transmission rate (WVTR) with targets based on what the technology needs for 25 year lifetime, proven lifetime of 25 years in solar module construction in the field, and lower cost; Testing of UBT Gen 2 under a wide range of conditions presented in this report failed to reveal any failure mode. Therefore UBT Gen 2 is known to be highly durable. 3M will continue to test towards statistically validating a 25 year lifetime under 3M funding; Transfer Generation-2 UBT from the pilot line to the full-scale manufacturing line within three years; and This objective was fully met.

  12. Localization of orphan receptor TR3 mRNA in early developmental follicles in rat

    2000-01-01

    By in situ hybridization, the localization of orphan receptor TR3 mRNA has been observed in early developmental follicles. TR3 mRNA is first expressed in the ovarian interstitial cells on day 2 after birth, and then in granulosa cells (GC) in primary follicles on day 4. The expression level of TR3 mRNA in GC increases following the follicular development. Its higher expression can be observed in the outer layer of GC and inner layer of theca cells (TC) on day 6, where the cells present active proliferation and differentiation. The expression of TR3 is in an increasing manner until the large antral follicles on day 30. The mRNA is only expressed in the healthy, but not atretic follicles in adult rat ovaries. Injection of epidermal growth factor (EGF) has dramatically enhanced its expression in the early stage of developmental follicles. It is therefore suggested that TR3 may play a role in regulating growth and differentiation of ovarian somatic cells in the early stage, and its expression is regulated by EGF.

  13. First results of multichord soft x-ray detection array on the U-3m torsatron

    A miniature pinhole camera array for spatially and temporally resolved measurements of soft X-ray plasma emission has been recently installed on the U-3M. The diagnostics has been tested in different types of the U-3M discharge. In low density frame antenna discharges with so-called ''H-like'' transition a fast SXR emission profile modification is observed. A phase shift of the SXR perturbation induced by the transition as well as different shapes of the perturbation is observed in different channels. The transition can be associated with MHD instability. Different shapes of the SXR emission profile has been observed in different discharge conditions. The SXR array is en excellent tool for study different types of the MHD activity. Different types of the low frequency MHD activity have been observed in the U-3M torsatron. The recently installed SXR diagnostics opens opportunity of detailed studies of the MHD activity together with its driver - the plasma pressure gradient. In the paper we are presented recent experimental results obtained with the use of SXP, without deep analysis these experiments

  14. Customer Relationship Management System with USCM-AKD Approach of D3M

    Ch. Raja Ramesh

    2010-09-01

    Full Text Available Customer Relationship Management (CRM for short System emerged in the last decade to reflect the central role of the customer for the strategic positioning of a company. One of the most significant changes in the practice of marketing during the last decade is the shift in emphasis from a transaction orientation customer to the CRM. Now a day’s it is an important edge but now a necessary tool for survival. CRM competence is very important source for enterprises to build and sustain competitive advantage. With the extensive applications in CRM enterprises have plenty of customer data. Main view of CRM is customer understanding, which is properly done will helps to understand customers and thus increases customer life time value. Effectively build CRM will maintain good relationships with customers. Companies have invested or are planning to invest huge amounts to implement CRM strategies, tools and infrastructures inorder to attract and retain profitable customers in today’s increasingly competitive markets. This paper introduces the architecture of RM based on Domain Driven Data Mining (D3M for short and with advanced technologies for knowing winning strategies. Italso discusses the important steps of designing the data warehouseand describes the meaning of D3M applied to the CRM and finally evolving of D3M to individual service are presented.

  15. ICRF plasma production and heating in the URAGAN-3M torsatron

    The results of experimental and theoretical studies of Alfven wave production and heating of plasma in the frequency range below the ion cyclotron frequency (ω0 ci) are presented. Several types of antenna have been studied for plasma RF production and heating in the URAGAN-3M torsatron (R = 100 cm, apl ≤ 12.5 cm, B ≤ 1.3 T): A frame type antenna (FTA) conventionally used for plasma RF production and heating with the best operational properties at low and moderate plasma densities (n-bare ≤ 5 x 1012 cm-3); compact three-half-turn antenna (THTA) proposed for plasma heating and density ramp up (up to 3 x 1013 cm-3) after the low density target plasma (n-bare ≥ 4 x 1011 cm-3) had been produced by FTA; recently proposed antenna of combined type (''crankshaft''), which has the best properties of both above mentioned antennae in the whole range of densities. The excitation of the electromagnetic fields in URAGAN-3M plasmas by FTA, THTA and crankshaft antenna has been studied numerically using 1-D wave code. To study the dynamics of RF plasma production in the URAGAN-3M torsatron the 0-dimensional code have been used. The results of calculations showed better performance of crankshaft antenna compared with FTA and THTA in the whole range of plasma densities. When using the THTA at the scenario with FTA as a target plasma source, the experiments performed showed the possibility of dense plasma production (n-bare > 2 x 1013 cm-3) and heating, which had not been obtained earlier in the URAGAN-3M torsatron. The shifted towards the plasma core power deposition profile of THTA resulted in modification of plasma density profile and improvement in plasma confinement. The preliminary experiments with crankshaft antenna on plasma production showed that this antenna can produce the dense (up to 1013 cm-3) plasma in the URAGAN-3M without any additional source of target plasma and it can be used for subsequent Alfven heating. (author)

  16. Inferencias sobre Grafos

    Sira M. Allende

    2002-05-01

    Full Text Available El estudio de un juego puede ser modelado asumiendo que solo algunas partidas son observadas. Entonces el árbol del juego debe ser estimado utilizando información muestral. Similarmente ocurre al obtener información sobre el comportamiento de las decisiones tomadas por individuos muestreados sobre un árbol de decisión teórico. Al considerar una medida de probabilidad que caracterice el comportamiento de redes aleatorias se puede obtener un estimado del árbol asociado. Este problema es el analizado en este trabajo. Algunos resultados experimentales obtenidos usando Recocido Simulado ilustran el procedimiento. Su papel en el estudio de modelos económicos y de mercadeo es discutido.

  17. Escrito sobre el cuerpo

    Antonio Malalana Ureña

    2013-09-01

    Full Text Available El catálogo, en una edición bilingüe español-inglés, es una pequeña guía de la exposición Shirin Neshat. Escrito sobre el cuerpo, muestra que se integra dentro de los actos de PHOTOESPAÑA13, el festival internacional de fotografía y artes visuales. El esquema del libro es sencillo y los textos son extremadamente divulgativos. El primero de ellos, Escrito sobre el cuerpo (pp. 10-15, cuyo autor es Octavio Zaya, comisario de la exposición, resume la trayectoria de esta intelectual, que "interactúa" con la fotografía y los formatos audiovisuales, y nos presenta la argumentación narrativa de los documentos expuestos, contextualizando la obra recopilada.

  18. Estudios sobre Borges

    Facultad de Humanidades y Ciencias de la Educación

    1991-01-01

    Contenidos de la obra: De Barthes a Pierre Menard | José Luis De Diego Pierre Menard, autor del Quijote: De la poligrafía al fraude | Andrea Cucatto Homenaje a Roberto Arlt: La otra cara de la moneda | Fabio Espósito Emma a través del espejo: Una lectura de Emma Zunz | Graciela Beatriz Goldchluk Sobre el concepto de verdad en Borges | Sergio Pastormerlo

  19. Sobre genes y electrones

    Martín Pereda, José Antonio

    1992-01-01

    El autor reflexiona sobre un artículo publicado en una revista, en el que se pronosticaba un declive para los científicos dedicados a la física y la ciencia armamentística, debido al fin de la guerra fría, y un ascenso al poder de los biólogos y de todos aquellos relacionados con las ciencias y las tecnologías de la vida.

  20. 1H and 7Li NMR in li2-xhxmo3 (m = Ti, Zr)

    Baklanova, Ya

    2008-01-01

    Nuclear magnetic resonance (NMR), Raman spectroscopy and thermogravimetric methods were used to study the peculiarities of lithium ion replacement by protons in lithium metallates Li2MO3 (M=Ti, Zr). In this article we show that almost all protons in the final substitution products H2MO3 enter into the crystal structure. All protons in zirconium hydroxide belong to hydrogen-bonded OH-groups. Contrary, titanium hydroxide contains both hydrogen-bonded and isolated OH-groups. Protons in H2ZrO3 fo...

  1. Study on adaptation of radiation sterilization of 3M Steri-DrapeTM

    Based on ISO11137, bioburden of 3M Steri-DrapeTM and the sterilization dose were determined. Results indicated that the adjusted average bioburden was 3082.5 cfu per device, verification dose was 12.6 kGy and the minimum sterilization dose was 26.8 kGy (SAL 10-6). The irradiated sample products were tested to verify properties of the package materials and biocompatibility of the device. Results showed that after the irradiation and accelerated aging test, the sample products and the package were qualified. The device remained sterile and no adverse response was found in cytotoxicity test, and animal test and clinical applications

  2. Theoretical study of 'Mixed' ligands superhalogens: Cl-M-NO3 (M = Li, Na, K)

    Zhao, Xinghua; Liu, Weihui; Wang, Jiesheng; Li, Chun; Yuan, Guang

    2016-08-01

    MCl2-, M(NO3)2-, and (Cl-M-NO3)- (M = Li, Na, K) species are systematically investigated using the density functional theory. In all the cases studied, the vertical detachment energies (VDEs) exceed the electron affinity of chlorine atom, leading to the conclusion that MCl2-, M(NO3)2- and (Cl-M-NO3)- are superhalogens. The VDEs of (Cl-M-NO3)- are between that of MCl2- and M(NO3)2-, showing that replacing one ligand with a larger electronegative ligand leads to the higher VDE. Superhalogens with suitable VDEs can be built by using different ligands.

  3. Zinc finger protein TTP interacts with CCL3 mRNA and regulates tissue inflammation*

    Kang, Ju-Gyeong; Amar, Marcelo J.; Remaley, Alan T.; Kwon, Jaeyul; Blackshear, Perry J.; Wang, Ping-yuan; Hwang, Paul M.

    2011-01-01

    Zinc finger protein tristetraprolin (TTP) modulates macrophage inflammatory activity by destabilizing cytokine mRNAs. Here, through a screen of TTP-bound mRNAs in activated human macrophages, we have identified CC chemokine ligand 3 (CCL3) mRNA as the most abundantly bound TTP target mRNA and have characterized this interaction via conserved AU-rich elements. Compared to the wild-type cells, TTP−/− macrophages produced higher levels of LPS-induced CCL3. In addition, the plasma level of CCL3 i...

  4. Integrated acquisition system of experimental data for Uragan-2M and Uragan-3M

    The paper describes the integrated data acquisition system representing in real time the parameters of plasma confined in stellarator-type fusion devices Uragan-2M and Uragan-3M, which are under operation in the Institute of Plasma Physics of NSC KIPT. This system provides the synchronous multichannel high-speed measurements of electric signals coming from the sensors of the device equipment and plasma diagnostic equipment, data acquisition, transportation and graphical display of information, archiving it in the server and in the electronic data repository. The system gives to the users the possibility of access to the files with the registered diagnostic information.

  5. Measurements of neutron fluxes and cadmium ratio at equilibrium core in JRR-3M

    Construction and characteristics tests of JRR-3M (Modified JRR-3) had been completed on October 1990, and the reactor reached to equilibrium core in July 1991. Measurements of neutron flux and cadmium ratio in Hydraulic irradiation facility (HR) and Pneumatic irradiation facility (PN) at 20 MW reactor power were carried out for the equilibrium core from May to August 1991 and for the latest core in April 1993. The results at the equilibrium core and the latest core are described in this paper. (author)

  6. Assessment of irradiation effects on beryllium reflector and heavy water tank of JRR-3M

    Murayama, Yoji; Kakehuda, Kazuhiro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-10-01

    The JRR-3M, a swimming pool type research reactor with beryllium and heavy water reflectors, has been operated since 1990. Since the beryllium reflectors are close to fuel and receive high fast neutron fluence in a relatively short time, they may be subject to change their dimensions by swelling due mostly to entrapped helium gaseous. This may bend the reflectors to the outside and narrow gaps between the reflectors and the fuel elements. The gaps have been measured with an ultrasonic thickness gage in an annual inspection. The results in 1996 show that the maximum of expansion in the diametral directions was 0.6 mm against 1.6 mm of a managed value for replacement of the reflector. A heavy water tank of the JRR-3M is made of aluminum alloy A5052. Surveillance tests of the alloy have been conducted to evaluate irradiation effects of the heavy water tank. Five sets of specimens of the alloy have been irradiated in the beryllium reflectors where fast neutron flux is higher than that in the heavy water tank. In 1994, one set of specimens had been unloaded and carried out the post-irradiation tests. The results show that the heavy water tank preserved satisfactory mechanical properties. (author)

  7. Calculation of fine neutron spectrum in irradiation holes in fuel region of JRR-3M

    The authors have a plan to evaluate TRU neutron cross sections based on the activation experiments by using JRR-3M. Fine neutron spectrum expressed by 107 energy group structure at irradiation holes in fuel region of JRR-3M core, which was utilized to analyze experimental data, was calculated by 2 step calculation. The first step is the whole core calculation taking account of burnup history and control rod pattern, and the second step is the irradiation hole calculation without any homogenization of irradiation hole components by taking into account of the neutron spectrum of surrounding region. Fine neutron spectra calculated by 2 step calculation were compared with the experimental results on reaction rate, both agreed within several percents relatively. In the comparison of absolute values, however, the maximum difference was up to 30 percents in the vicinity of control rods. This originates from the neutron transport effect around control rods. An improvement for the treatment of neutron transport effect is needed to get higher accuracy. (author)

  8. Unique Roll-Off Roof for Housing 1.3 m Telescope at Devasthal, Nainital

    Bangia, Tarun

    2016-05-01

    Aryabhatta Research Institute of Observational Sciences (ARIES) had set up a 1.3 m telescope at Devasthal, Nainital, India in the year 2010. Country's largest roll-off roof was indigenously designed, fabricated and installed on top of a building (17 × 8 m) for housing 1.3 m telescope. Telescope was supplied by M/s DFM Engineering Inc., USA to ARIES and was installed in the building with unique roll-off roof to protect it from external environment. Roll-off roof was designed and fabricated considering various parameters and available manpower and resources at ARIES. This paper presents mechanical development work, simple but distinct design approach and innovative selection of materials to economically manufacture roll-off roof of large size (8 × 8 × 4 m) at hilly remote site of Devasthal situated in Central Himalayan region. All operations in the roof viz. opening of shutters and rolling of roof were motorized to facilitate observers during night observations.

  9. Apuntes sobre liderazgo

    Contreras, Manuel E.

    2010-01-01

    Este trabajo presenta una breve síntesis de las principales teorías de liderazgo y se centra sobre el enfoque de liderazgo adaptativo de Ronald Heifetz. El documento originalmente fue desarrollado para las sesiones de educación a distancia de INDES. Ha sido revisado para usar en otros ámbitos de capacitación y ha sido utilizado en sesiones presenciales llevadas a cabo por INDES, como por otras entidades en universidades y centros de capacitación de America Latina.

  10. Informe APEI sobre movilidad

    Arroyo Vázquez, Natalia

    2011-01-01

    Este informe incluye una amplia aproximación al concepto de movilidad, desde un punto de vista introductorio, que nunca antes en nuestro ámbito había abarcado todos los aspectos que tienen que ver con él, desde cuestiones técnicas como los dispositivos móviles, sistemas operativos y navegadores, conectividad y estándares —cuya intención es poder comprender todos aquellos aspectos relacionados con la movilidad y que tienen una incidencia directa sobre los contenidos— hasta otras más relacionad...

  11. Sobre el razonamiento judicial

    Asís Roig, Rafael de

    1998-01-01

    El trabajo elabora modelos a través de los cuáles es posible reconstruir la argumentación judicial plasmada en las sentencias y, a la vez, hacer explícitas las reglas que sirven de justificación a sus decisiones, y el marco normativo utilizado como referencia. El estudio analiza tanto los pronunciamientos sobre hechos como los que se refieren a la calificación jurídica, en principio, desde una perspectiva descriptiva. Ahora bien, también se llevan a cabo reflexiones y propuestas que van más a...

  12. Automated 1.3-m near-infrared telescope system triggered by gamma-ray burst

    Murakami, Toshio; Yonetoku, Daisuke; Kinoshita, Shin; Masui, Hiroki; Okuno, Shinya; Yoshinari, Satoru; Kidamura, Takashi; Tanabe, Sachiko; Yokota, Satoshi; Kobayashi, Yukiyasu; Nakagawa, Takao; Nakamura, Takashi

    2006-06-01

    The design for robotic telescopes to observe Gamma-Ray Burst (GRB) afterglows and the results of observations are presented. Quickly fading bright GRB flashes and afterglows provide a good tool to study an extremely early universe. However, most large ground-based telescopes cannot afford to follow-up the afterglows and flashes quickly within a few hours since a GRB explosion. We re-modeled the existing middle-class 1.3 m ø telescope of the near infrared band at ISAS in Japan to match for the above requirement. We also set a small telescope of 30 cm diameter with a conventional CCD. These telescopes can monitor afterglows quickly within a few minutes in J, H, Ks and R band with a grism spectrometer.

  13. Spectroscopic study of Mq3 (M=Al, Ga, In, q=8-hydroxyquinolinate) at high pressure

    A high-pressure spectroscopic investigation of OLED materials with generic formula Mq3 (M=Al, Ga, In, q=8-hydroxyquinolinate) has been carried out. The meridional isomer of Alq3, Gaq3, Inq3 and facial isomer of Alq3 have been produced and their corresponding photoluminescence emission energy has been studied as a function of the cation, pressure, excitation wavelength and isomer. A redshift in the order of 0.3 eV takes place for the pure-meridional isomer compounds in the 0-8 GPa range. We have detected the occurrence of pressure-induced phase transitions presenting hysteresis to ambient conditions. In the case of the facial isomer, luminescence does not significantly redshift until very high pressure. We interpret these features in terms of the enhancement of the intermolecular interaction.

  14. Determination of the first hydrolysis constant of Europium (III) in 3 M of ionic strength

    The first hydrolysis constant of Eu3+ has been determined at 303 K and 3 M (NaCl) ionic strength. A solvent extraction method was used, the extractant was dibenzoylmethane in benzene and di glycolate anion in the aqueous phase provided competitive complexation. The tracer solution was 152m1 Eu (III) in water. The radioactive solution of europium was obtained by neutron irradiation of europium nitrate solutions at pH 3.0, in a TRIGA Mark III nuclear reactor at a neutron flux of 1 x 1013 cm-2 s-1. The half life of the produced isotope, 152m1 Eu (9.3 h), was verified by means of a Ge H detector and no interfering radiations were observed in the spectra. (Author)

  15. 嵌入式工控机系统ARK-6310-3M04E

    2009-01-01

    研华科技近期推出嵌入式工控机系统ARK-6310—3M04E,该产品配有Intel。ATOM处理器、Intel 945GSE芯片组和集成Mini—ITX母板,采用无风扇设计,可在恶劣环境中无噪声并可靠工作。该款紧凑、坚固型工业系统集成在一个多功能嵌入式机箱中,超紧凑的坚固构造,坚固的耳柄允许用户方便移动设备,扩展性能强,

  16. 'Scorpion-like' dithiocarbamato-carboxylate ligands for linking M(CO)3+ (M = Tc, Re)

    Complexation of M(CO)3+ (M = Tc, Re) with dithiocarbamato-carboxylate ligands was studied. It was found that the dithiocarbamate chelation unit has rather high affinity to M(CO)3+ species and the resulting complexes are extremely stable in a wide pH range. The complex M(CO)3[S2CN(CH2COO)2] is monomeric in solution (ESI MS) and dimeric in the crystal phase (single-crystal XRD). The 'scorpion-like' dithiocarbamato-carboxylate ligands were prepared; it was shown that C5 chain is long enough to reach back to the free coordination vacancy in M(CO)3+ core and to block it. (author)

  17. Electronic structure and magnetism of KMF3 (M=Mn,Fe,Co,Ni)

    Pari, G.; Mathi Jaya, S.; Asokamani, R.

    1994-09-01

    Antiferromagnetic electronic-structure calculations of the perovskite fluorides KMF3 (M=Mn,Fe,Co,Ni) carried out using the linear muffin-tin orbital method are reported here. The calculations have successfully predicted the insulating gaps of the systems KMnF3 and KNiF3. However, in the cases of KFeF3 and KCoF3 the insulating gap could not be accounted for by these calculations and this is found to be due to the fact that the spin-density-functional theory is inadequate to show the splitting of the M t2g bands. However, the magnetic moments obtained from the calculations are comparable to the experimental values, and also the calculated density of states show good agreement overall with the photoemission data.

  18. Modeling the hydrothermal circulation and the hydrogen production at the Rainbow site with Cast3M

    Perez, F.; Mügler, C.; Charlou, J.; Jean-baptiste, P.

    2012-12-01

    On the Mid-Atlantic Ridge, the Rainbow venting site is described as an ultramafic-hosted active hydrothermal site and releases high fluxes of methane and hydrogen [1, 2]. This behavior has first been interpreted as the result of serpentinization processes. But geochemical reactions involving olivine and plagioclase assemblages, and leading to chlorite, tremolite, talc and magnetite assemblages, could contribute to the observed characteristics of the exiting fluid [2]. The predominance of one of these geochemical reactions or their coexistence strongly depend on the hydrothermal fluid circulation. We developed and validated a 2D/3D numerical model using a Finite Volume method to simulate heat driven fluid flows in the framework of the Cast3M code [3, 4]. We also developed a numerical model for hydrogen production and transport that is based on experimental studies of the serpentinization processes [5-6]. This geochemical model takes into account the exothermic and water-consuming behavior of the serpentinization reaction and it can be coupled to our thermo-hydrogeological model. Our simulations provide temperatures, mass fluxes and venting surface areas very close to those estimated in-situ [7]. We showed that a single-path model [8] was necessary to simulate high values such as the in-situ measured temperatures and estimated water mass fluxes of the Rainbow site [7]. This single-path model will be used to model the production and transport of hydrogen at the Rainbow hydrothermal site. References [1]Charlou et al. (2010) AGU Monograph series. [2]Seyfried et al. (2011) Geochim. Cosmochim. Acta 75, 1574-1593. [3]http://www-cast3m.cea.fr. [4]Martin & Fyfe (1970) Chem. Geol. 6, 185-202. [5] Marcaillou et al. (2011) Earth and Planet. Sci. Lett. 303, 281-290. [6]Malvoisin et al. (2012) JGR, 117, B01104. [7]Perez et al. (2012) submited to Computational Geosciences. [8]Lowell & Germanovich (2004) AGU, Washington DC, USA.

  19. Sobre historia mundial hoy

    Vera Weiler

    2010-08-01

    Full Text Available Los procesos de globalización son una realidad; su enorme impacto sobre la vida humana los ha convertido en un tema recurrente sobre el que se escribe y se comenta a diario también en Colombia. Los libros que de ellos tratan, ante todo los que 10 hacen en tono crítico, baten records en la industria editorial en todo el mundo. Las expectativas que acerca del futuro abrigan cientos de millones de personas se relacionan con 10 que ellas esperan, para bien o para mal, de la globalización. Las posturas que los gobernantes ocupan al respecto en el mundo son, cuando menos de aceptación, generalmente de activa participación en pos de la globalización. Por un lado, crece la preocupación y se multiplican las protestas; por el otro, dominan los razonamientos de los especialistas en materia de maximización de los rendimientos de los capitales que presentan la globalización, al estilo que se viene imponiendo, como el camino ineludible del gobierno universal de la eficiencia. ¿Tienen que decir algo los historiadores frente a todo esto?.

  20. Subproject plan for demonstration of 3M technology for treatment of N Basin water

    A dissolved radionuclides removal demonstration is being conducted at the 105-N Basin as part of the 100-N Area Projects' policy of aggressively integrating innovative technologies to achieve more cost effective, faster, and/or safer deactivation operations. This subproject plan demonstrates new technology (marketed by the 3M trademark Company) that absorbs specific ions from water. The demonstration will take place at the spent fuel basin at the N Reactor facility. The 105-N Basin contains 1 million gal of water consisting of approximately 32 Ci of dissolved 90Sr at a concentration of 8.4 uCi/L and 7.3 Ci of dissolved 137Cs at a concentration of 1.92 uCi/L. The Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement [Ecology et al. 1990]) Milestone M-16-01E-T2 requires the initiation of pretreatment and removal of all N Reactor fuel storage basin waters by September 30, 1996, pursuant to the N Reactor Deactivation Program Plan (WHC 1993). 105-N Basin dewatering is on the critical path for overall deactivation of N Reactor by March 1997. The 105-N Basin Deactivation Program Plan (BHI 1995) includes removing debris, hardware, algae and sediment from the basin, followed by pretreatment (filtration) and removal of the 1005-N Basin water. Final water removal is currently scheduled for September 30, 1996. The recommended method of the 105-N Basin water is the treatment of the water at the Effluent Treatment Facility (ETF) in the 200 East Area. The demonstration of the 3M technology could be a feasible treatment alternative to the ETF if the ETF is not available to meet the project schedule or if additional pretreatment is needed to reduce the inventory of radioactive species to be handled at the ETF. Demonstration of this technology could be of value for other fuel basins at the Hanford Site and possibly other US Department of Energy (DOE) sites and non- DOE nuclear power plants

  1. KEPADATAN JENTIK Aedes aegypti SEBAGAI INDIKATOR KEBERHASILAN PEMBERANTASAN SARANG NYAMUK (3M PLUS: DI KELURAHAN SRONDOL WETAN, SEMARANG

    Bhinuri

    2008-06-01

    Full Text Available Aedes aegypti larva density as an indicator of the success in mosquito breeding place irradication in East Srondol village, Semarang. Interventions have been done to reduce DHF incidence, such as fogging and suggestion to do 3 M plus, but ABJ (larva’s number of Semarang is still under the target. The best intervention is by doing 3M plus. The aims of this research are to know the relation between social characteristics, knowledge, and attitude with the habitual elimination 3 M Plus of mosquito sites, the relation between the habitual elimination 3 M Plus of mosquito sites with larva density, the larva density and also the prediction model of larva density from the habitual elimination 3 M Plus of mosquito sites. The research has been done at Kelurahan Srondol Wetan, with observational, quantitative, and explanatory research by using cross-sectional survey method. The population were the houses with the respondent-the person who did the habitual elimination 3 M Plus of mosquito sites. Sample number were 188 with stratified random sampling. The statistic test was the Kendalls Tau and multiple regresion. The result showed that there are relation between social characteristics such as education, family number, job, and salary, with the habitual elimination 3 M Plus of mosquito sites but there is no relation with age, knowledge and attitude. There are also relations between the habitual elimination 3 M Plus of mosquito sites at bath tub, water tub and also bucket with the larva density. Based on those results, Health Department of Semarang especially Community Health Center in Srondol Wetan expected to do health education about 3 M Plus at bath tub, bucket and water tub. Suggestion also addressed to the next researcher to use purposive sampling and water storage classification for the same research.

  2. Excertos sobre o sedentarismo

    Alexandre Palma

    2014-09-01

    Full Text Available O sedentarismo tem sido tratado como algo perfeitamente determinável, objetivo e, portanto, que pode ser apreendido. Por outro lado, o conceito de sedentarismo ainda permanece questionável e, por conseguinte, os instrumentos mostram-se inconsistentes. Neste sentido, o objetivo do presente estudo foi mostrar que diferentes discursos de verdade vêm concorrendo por esse conceito, o que nos motiva a pensar qual é a verdade ou, até mesmo, se há alguma verdade sobre ele. Após apresentarmos diferentes possibilidades de compreender o sedentarismo, através do uso de aforismos, entendemos que postular um discurso como verdade talvez apenas signifique que as pessoas nele creem e que há uma vontade de verdade como uma vontade voltada para o poder.

  3. Voz sobre frame relay

    D´Elia, Gabriel Anibal

    2000-01-01

    Esta tesis trata el tema de VOFR, desde la digitalización de la voz hasta su transmisión a través de dicha red, así también como la comparación con otros medios de transporte como VOIP. Dada las características del protocolo frame relay y su disponibilidad se eligió como el medio más apropiado para la transmisión de voz y datos en forma integrada sobre una misma red. El trabajo comienza con una breve explicación de la voz, su digitalización y forma actual de transmisión a través de una red di...

  4. Visualization and measurement of pressurized multiphase flow using neutron radiography of JRR-3M system

    Katoh, Yasuo [Yamaguchi Univ. (Japan); Matsubayasi, Masahito

    1998-01-01

    Concerning the transient phenomenon of solid-gas two-phase flow, an attempt was made to visualize and measure a flow phenomenon in which three-dimensional bubbles occurred, grew and collapsed in the vicinity of a gas injection nozzle while solid particles were circulating. Such a phenomenon could not or hardly be visualized and measured by conventional methods. Such two-phase flow was visualized using neutron radiography, its characteristics measured and the usefulness of the visualization by neutron radiography confirmed. For this purpose, three-dimensional fluidized bed vessels, rectangular or cylindrical-shaped, made of steel or aluminum sheet, were prepared. Polyethylene or glass beads were used as solid particles and activated carbon particles as the tracer. In the experiment, nitrogen gas was blown into the vessel from one nozzle and distributors provided at the bottom of the vessel and exhausted from the top via the exhaust valve, by which the pressure in the vessel was controlled. The imaging was done in the following way: A test chamber was provided beside the vessel to receive neutron beams from the JRR-3M system, the intensity of transmitted neutrons was converted to visible light by scintillator and the images were videotaped. The initial objectives of visualizing and measuring bubbles occurring, growing and collapsing and solid particles circulating in the solid-gas two-phase flow have been achieved by means of neutron radiography. (N.H.)

  5. CRM System Using UI-AKD Approach of D3M

    J.N.V.R.Swarup kumar,

    2010-03-01

    Full Text Available Customer Relationship Management has entered the mainstream. Despite the uncertainty of the economy, CRM is being thrust into corporate budgets and talked about as a critical initiative by numerous of companies. It has gone from being an important edge in the business world to a necessary tool for survival. Building an effective CRM system can get more effectively in acquiring new customers, increasing value of existing customers and retaining good customers. At the same time, the data of data warehouse will offer the best dataresource for the application of Domain Driven Data Mining (D3M for short on CRM. This paper introduces CRM and managing relationships with customers has become a critical organizational competency. Get winning strategies with the latent advanced technologies. Then ntroduces the architecture of CRM based on Domain Driven Data Mining, discusses the main steps of designing the Data warehouse and describes the meaning of Domain Driven Data Mining applied to CRM. Atlast, the promoting effects of Domain Driven Data Mining to individual service are presented .

  6. High-pressure phase transition of MH3 (M: Er, Ho)

    Hou, Pugeng; Tian, Fubo; Li, Da; Chu, Binhua; Zhao, Zhonglong; Liu, Bingbing; Cui, Tian

    2014-08-01

    Motivated by the potential high temperature superconductivity in hydrogen-rich materials, high-pressure structures of ErH3 and HoH3 were studied by using genetic algorithm method. Our calculations indicate that both ErH3 and HoH3 transform from P-3c1 structure to a monoclinic C2/m structure at about 15 GPa, and then transforms into a cubic Fm-3m structure at about 40 GPa. ErH3 and HoH3 adopt the same P63/mmc structure with space group P63/mmc at above about 220 and 196 GPa, respectively. For ErH3, the P63/mmc phase is stable up to at least 300 GPa, while for HoH3, a phase transformation P63/mmc → Cmcm occurs at about 216 GPa, and the Cmcm phase is stable up to at least 300 GPa. The P-3c1 ErH3 and HoH3 are calculated to demonstrate non-metallic character, and the other phases are all metallic phases.

  7. Magnetic properties and specific heat of MPS3 (M=Mn, Fe, Zn)

    The magnetic properties and specific heat of MPS3 (M=Mn, Fe and Zn) have been investigated. While ZnPS3 is non-magnetic, MnPS3 and FePS3 are antiferromagnets with the Neel temperature TN of 78 and 118 K, respectively. Nevertheless, the specific heat of MnPS3 and FePS3 is smaller than that of ZnPS3 below about 20 K. The temperature dependence of the magnetic specific heat CM of MnPS3 shows a broad hump which is characteristic to the two dimensional magnetic materials and a small sharp peak at TN. On the other hand, that of FePS3 shows a large sharp peak at TN. As for FePS3, the temperature dependences of the magnetization M and CM are well reproduced by taking account of the magneto-elastic effect which introduces an additional term proportional to the square of the average value of the spin to the exchange coupling constant. As for MnPS3, marked two dimensional characters appear in the temperature dependence of M and CM. The observed TN is much smaller than the paramagnetic Curie temperature of 240 K obtained from the temperature dependence of the magnetic susceptibility at high temperature

  8. $P^{3}M-SPH$ simulations of the Lyman-$\\alpha $ Forest

    Theuns, T; Efstathiou, G P; Pearce, F R; Thomas, P A; Theuns, Tom; Leonard, Anthony; Efstathiou, George

    1998-01-01

    (Abridged) We investigate the importance of several numerical artifacts such as lack of resolution on spectral properties of the Lyman alpha forest as computed from cosmological hydrodynamic simulations in a standard cold dark matter universe. We assume an ionising background produced by quasars as computed by Haardt & Madau. We use a new simulation code based on P3M and SPH, which we compare in detail with a modified version of HYDRA (Couchman et al.) and published results of TREESPH (Hernquist et al.). The agreement is very good between all three codes. We then use our new code to investigate several numerical effects such as resolution on spectral statistics deduced from Voigt profile fitting. Our highest resolution simulation has a mass resolution of 2.1x10^5 solar masses. The column density distribution is converged but the b-parameter distribution is only marginally converged. The simulation reproduces both the HI column density and b-parameter distribution when we assume a high baryon density, Omeg...

  9. Theoretical studies of the paramagnetic perovskites MTaO{sub 3} (M = Ca, Sr and Ba)

    Ali, Zahid, E-mail: zahidf82@gmail.com [Center for Computational Materials Science, University of Malakand, Chakdara, Dir (Lower) (Pakistan); Khan, Imad; Ahmad, Iftikhar; Khan, M. Salman [Center for Computational Materials Science, University of Malakand, Chakdara, Dir (Lower) (Pakistan); Asadabadi, S. Jalali [Department of Physics, Faculty of Science, University of Isfahan, Hezar Gerib Avenue, Isfahan, 81744 (Iran, Islamic Republic of)

    2015-07-15

    In the present density functional studies, structural, mechanical and magneto-electronic properties of CaTaO{sub 3,} SrTaO{sub 3} and BaTaO{sub 3} perovskites have been investigated. The calculated structural parameters by DFT and analytical methods are found consistent with the experiments. The analytically calculated tolerance factors of these compounds as well as their mechanical properties show that they are stable in the cubic phase. Furthermore elastic properties show that these materials are ductile in nature and confirm that BaTaO{sub 3} is harder than the rest compounds. The calculated spin dependent magneto-electronic properties reveal the paramagnetic metallic nature of these compounds. The electrical conductivity curve demonstrates significant conductivity above room temperature. On the basis of the presented properties it is expected that these compounds could be efficient electrode materials and need experimental investigations. - Highlights: • MTaO{sub 3} (M = Ca, Sr and Ba) perovskites are investigated theoretically in the frame work of density functional theory. • Mechanical properties explain the stability of these compounds and show that BaTaO{sub 3} is more ductile. • The magneto-electronic studies reveal the paramagnetic metallic nature of these compounds. • Significant electrical conductivity is observed above room temperature.

  10. Lattice relaxation and ferromagnetic character of (LaVO3) m/SrVO3superlattices

    Schuster, Cosima B.

    2013-08-01

    The experimental observation that vanadate superlattices (LaVO 3)m/SrVO3 show ferromagnetism up to room temperature (Lüders U. et al., Phys. Rev. B, 80 (2009) 241102(R)) is investigated by means of density functional theory, and the band structure for m = 5 and 6 is calculated. A buckling of the interface VO2 layers is found in both cases, but subtle differences in bond length lead to very different properties for even and odd values of m: in the even case, the two interface VO2 layers effectively decouple from the adjacent LaO layers due to a strong bond length enhancement. This results into a local inversion of the orbital occupancy and to the confinement of the charge carriers. In the odd case, the amplitude of the bond length variation is smaller, so that the charge carriers spill into the deeper-lying VO2 layers, and spin-polarised interfaces are obtained. © Copyright EPLA, 2013.

  11. Oxidation, Reduction, and Condensation of Alcohols over (MO3)3 (M=Mo, W) Nanoclusters

    Fang, Zongtang; Li, Zhenjun; Kelley, Matthew S.; Kay, Bruce D.; Li, Shenggang; Hennigan, Jamie M.; Rousseau, Roger J.; Dohnalek, Zdenek; Dixon, David A.

    2014-10-02

    The reactions of deuterated methanol, ethanol, 1-propanol, 1-butanol, 2-propanol, 2-butanol and t-butanol over cyclic (MO3)3 (M = Mo, W) clusters were studied experimentally with temperature programmed desorption (TPD) and theoretically with coupled cluster CCSD(T) theory and density functional theory. The reactions of two alcohols per M3O9 cluster are required to provide agreement with experiment for D2O release, dehydrogenation and dehydration. The reaction begins with the elimination of water by proton transfers and forms an intermediate dialkoxy species which can undergo further reaction. Dehydration proceeds by a β hydrogen transfer to a terminal M=O. Dehydrogenation takes place via an α hydrogen transfer to an adjacent MoVI = O atom or a WVI metal center with redox involved for M = Mo and no redox for M = W. The two channels have comparable activation energies. H/D exchange to produce alcohols can take place after olefin is released or via the dialkoxy species depending on the alcohol and the cluster. The Lewis acidity of the metal center with WVI being larger than MoVI results in the increased reactivity of W3O9 over Mo3O9 for dehydrogenation and dehydration.

  12. Low temperature specific heat and thermoelectric power of UCu3M2Al7 alloys

    The specific heat and thermoelectric power of the UCu3M2Al7 alloys where M = Cr, Mn and Fe are presented. The specific heat has been measured in the temperature range 2.6-70 K in magnetic field H = 0 and 3 T using a homemade and full automatic calorimeter, whereas the thermoelectric power has been measured from 6 to 300 K employing a differential method with copper as reference material. The temperature dependence of the specific heat exhibits only a minute influence of magnetic field and no anomaly in the investigated temperature region. However, the coefficients of the electronic specific heat of all alloys are very close, being enhanced amount to about 200 mJ mol-1 K-2 at high temperature and to about 400 mJ mol-1 K-2 at low temperature. Strongly correlated electrons or crystallographic disorder are considered as a reason for these values. The thermoelectric power demonstrates moderate values within whole investigated temperature range

  13. The first-principle studies of the crystal phase transitions: Fd3m-MgAl2O4→F4-3m-MgAl2O4

    Magnesium aluminum spinel (MgAl2O4) is a major constituent of the shallow upper mantle. It is of great geophysical importance to explore its physical properties under high pressure and temperature. The first-principle density functional theory (DFT) with the plane wave along with pseudopotential was employed to obtain the total energy for both Fd3m-MgAl2O4 and F4-3m-MgAl2O4, which was used to generate the Gibbs free energy as a function of temperature and pressure with the quasi-harmonic Debye model. It is found that the phase transition temperature from Fd3m-MgAl2O4 to F4-3m-MgAl2O4 is beyond 452.6 K in the pressure regime studied, which is consistent with the experiment. The phase transition temperature is related to pressure by a linear function, i.e. T=8.05P+452.6, which is the first equation of this kind to describe the phase transition Fd3m→F4-3m. The elastic constants, equation of states and thermodynamic properties of Fd3m-MgAl2O4 are also reported in this paper to make a complete study.

  14. Error analysis for CO and CH4 total column retrievals from SCIAMACHY 2.3 ?m spectra

    Aben, I.; O. P. Hasekamp; Schrijver, H.; Gloudemans, A. M. S.

    2008-01-01

    International audience A detailed sensitivity analysis of the Iterative Maximum Likelihood Method (IMLM) algorithm and its application to the SCIAMACHY 2.3 ?m spectra is presented. The sensitivity analysis includes a detailed assessment of the impact of aerosols in the 2.3 ?m range. Results show that near strong aerosol sources mineral dust and biomass aerosols can have an effect of ~7?10% on the CH4 total columns retrieved from this wavelength range. Similar but somewhat larger effects ar...

  15. Initial operation and checkout of stratospheric aerosol gas experiment and Meteor-3M satellite

    Habib, Shahid; Makridenko, Leonid; Chu, William P.; Salikhov, Rashid; Moore, Alvah S., Jr.; Trepte, Charles R.; Cisewski, Michael S.

    2003-04-01

    Under a joint agreement between the National Aeronautics and Space Agency (NASA) and the Russian Aviation and Space Agency (RASA), the Stratospheric Aerosol Gas Experiment III (SAGE III) instrument was launched in low earth orbit on December 10, 2001 aboard the Russian Meteor-3M(1) satellite from the Baikonur Cosmodrome. SAGE III is a spectrometer that measures attenuated radiation in the 282 nm to 1550 nm wavelength range to obtain the vertical profiles of ozone, aerosols, and other chemical species that are critical in studying the trends for the global climate change phenomena. This instrument version is more advanced than any of the previous versions and has more spectral bands, elaborate data gathering and storage, and intelligent terrestrial software. There are a number of Russian scientific instruments aboard the Meteor satellite in addition to the SAGE III instrument. These instruments deal with land imaging and biomass changes, hydro-meteorological monitoring, and helio-geophysical research. This mission was under development for over a period of six years and offered a number of unique technical and program management challenges for both Agencies. SAGE III has a long space heritage, and four earlier versions of this instrument have flown in space for nearly two decades now. In fact, SAGE II, the fourth instrument, is still flying in space on NASA's Earth Radiation Budget Satellite (ERBS), and has been providing important atmospheric data over the last 18 years. It has provided vital ozone and aerosol data in the mid latitudes and has contributed vastly in ozone depletion research. Ball Aerospace built the instrument under Langley Research Center's (LaRC) management. This paper presents the process and approach deployed by the SAGE III and the Meteor teams in performing the initial on-orbit checkout. It further documents a number of early science results obtained by deploying low risk, carefully coordinated procedures in resolving the serious operational

  16. ErbB3 mRNA leukocyte levels as a biomarker for major depressive disorder

    Milanesi Elena

    2012-09-01

    Full Text Available Abstract Background In recent years, the identification of peripheral biomarkers that are associated with psychiatric diseases, such as Major Depressive Disorder (MDD, has become relevant because these biomarkers may improve the efficiency of the differential diagnosis process and indicate targets for new antidepressant drugs. Two recent candidate genes, ErbB3 and Fgfr1, are growth factors whose mRNA levels have been found to be altered in the leukocytes of patients that are affected by bipolar disorder in a depressive state. On this basis, the aim of the study was to determine if ErbB3 and Fgfr1 mRNA levels could be a biomarkers of MDD. Methods We measured by Real Time PCR ErbB3 and Fgfr1 mRNA expression levels in leukocytes of MDD patients compared with controls. Successively, to assess whether ErbB3 mRNA levels were influenced by previous antidepressant treatment we stratified our patients sample in two cohorts, comparing drug-naive versus drug-free patients. Moreover, we evaluated the levels of the transcript in MDD patients after 12 weeks of antidepressant treatment, and in prefrontal cortex of rats stressed and treated with an antidepressant drug of the same class. Results These results showed that ErbB3 but not Fgfr1 mRNA levels were reduced in leukocytes of MDD patients compared to healthy subjects. Furthermore, ErbB3 levels were not affected by antidepressant treatment in either human or animal models Conclusions Our data suggest that ErbB3 might be considered as a biomarker for MDD and that its deficit may underlie the pathopsysiology of the disease and is not a consequence of treatment. Moreover the study supports the usefulness of leukocytes as a peripheral system for identifying biomarkers in psychiatric diseases.

  17. Design report for a cryostable 3m diameter superconducting solenoid for the Fermilab Collider Detector Facility

    The Fermilab Collider Detector Facility (CDF) is a large detector system designed td study anti pp collisions at very high center of mass energies. The central detector for the CDF employs a large axial magnetic field volume instrumented with a central tracking chamber composed of multiple layers of cylindrical drift chambers and a pair of intermediate tracking chambers. The purpose of this system is to determine the trajectories, sign of electric charge, and momenta of charged particles produced with polar angles between 10 and 170 degrees. The magnetic field volume required for tracking is approximately 4 m long and 3 m in diameter. To provide the desired Δp/sub T//p/sub T/ less than or equal to 15% at 50 GeV/c using drift chambers with approx. 200μ resolution the field inside this volume should be 1.5 T. This field should be as uniform as is practical to simplify both track finding and the reconstruction of particle trajectories with the drift chambers. Such a field can be produced by a cylindrical current sheet solenoid with a uniform current density of 1.2 x 106 A/m (1200 A/mm) surrounded by an iron return yoke. For practical coils and return yokes, both central electromagnetic and central hadronic calorimetry must be located outside the coil of the magnet. This geometry requires that the coil and cryostat be thin both in physical thickness and in radiation and absorption lengths. This dual requirement of high linear current density and minimal coil thickness can only be satisfied using superconducting technology. In this report we describe a design for a cryostable superconducting solenoid intended to meet the requirements of the Fermilab ies TDF

  18. Synthesis of LaMO3 (M = Fe, Co, Ni) using nitrate or nitrite molten salts

    Research highlights: → The molten salt, synthesis temperature, the oxidising properties, the basicity and oxidation states of the melt play an important role in LaMO3 synthesis. → The system needs a careful optimisation of these parameters to obtain pure orthorhombic LaFeO3, hexagonal LaCoO3 and LaNiO3. Purely hexagonal LaNiO3 nanocrystals were successfully synthesized. → SEM analyses were taken to investigate how the different parameters affect the microstructure of the samples. → The specific surface area and crystallite size of LaMO3 show much difference in different system. - Abstract: Perovskite compound LaMO3 (M = Fe, Co, Ni) nanocrystals were successfully synthesized in molten nitrates or nitrites from a mixture of lanthanum nitrate and an M-containing nitrate for 2 h. The effect of the various process parameters on the phase purity, crystallite size, specific surface area and morphology of the synthesized nanocrystals were systematically studied by XRD, scanning electron microscopy (SEM), simultaneous TG/DSC and BET measurements. The results showed that salt medium, annealing temperatures (mainly 450-850 oC), oxidising properties and basicity of the melt played an important role in the synthesis of LaMO3. The addition of Na2O2 facilitated the reaction between La2O3 and NiO or Co3O4, leading to the formation of LaNiO3 and LaCoO3 at a much lower temperature of 450 oC. Pure hexagonal LaNiO3 nanocrystals were obtained in molten NaNO3-KNO3 eutectic with Na2O2 at 550-750 oC.

  19. Tumor Necrosis Factor-related Apoptosis Ligand Induces Apoptosis in Prostate Cancer PC-3M Cell Line

    CHEN Zhohui; WANG Huafang; GU Longjie; YE Zhewei; XIAO Yajun

    2005-01-01

    To study the effect of tumor necrosis factor-related apoptosis inducing ligand (TRAIL)on PC-3M cell line, PC-3M cell line was incubated with gradient concentrations of TRAIL for 4-24h. Annixin-Ⅴ fluorescence staining and TUNEL method were employed to detect the apoptosis of PC-3M cells. The morphology of apoptotic PC-3M cells was observed by electron microscopy. The relationship between TRAIL concentrations and the percentage of apoptotic cells was evaluated by flow cytometry. The proliferation inhibitory ratio was calculated by using MTT colorimetry. Our results showed that apoptosis of PC-3M cells could be induced by treatment with TRAIL for at most 4 h. The results of flow cytometry and MTT colorimetry demonstrated a time- and concentration-dependent relationship between cell apoptosis rate and TRAIL concentration. It is concluded that apoptosis of PC-3M cells can be induced by TRAIL. Because of the selective killing effect of TRAIL on tumor ceils, it may become a potential alternative for the treatment of advanced prostate cancer.

  20. Refletindo sobre idosos institucionalizado

    Cenir Gonçalves Tier

    2004-06-01

    Full Text Available Trata-se de uma pesquisa qualitativa, descritiva que teve por objetivo identificar como vem sendo o relacionamento idoso-família, identificando os motivos que levaram os familiares a optarem pela institucionalização do seu idoso, obtendo-se também a visão da família sobre o cuidado no lar. Para coleta dos dados utilizou-se um instrumento com perguntas abertas. A coleta dos dados efetivou-se nos meses de agosto de 2002 a julho de 2003, sendo sujeitos da pesquisa, familiares de idosos de uma instituição asilar em um município da região noroeste do Rio Grande do Sul. Através da análise de conteúdo constatou-se que a maior dificuldade encontrada pela família, visando dispensar cuidados ao idoso é a "falta de tempo para cuidar" do seu familiar idoso, pois a maioria deles exige cuidados em tempo integral.

  1. Sobre el nombre "Quechua"

    Rodolfo Cerrón-Palomino

    1985-06-01

    Full Text Available Uno de los primeros problemas con el que a menudo tropiezael estudioso de los idiomas ágrafos, como es el caso de las lenguasaborígenes de América, es el de su denominación (glotónimo.En la medida ,en que, por razones históricas, las noticias sobretales lenguas, y por consiguiente los primeros estudios sobre lasmismas, surgen a partir del contacto con los miembros de la civilización occidental, los nombres de los distintos idiomas, así comode los grupos étnicos que los manejan, son el resultado casi siempre arbitrario cie designaciones fortuitas hechas por viajeros, misiioneros y exploradores, quienes por lo general se basan, para ello, bien en descripciones físicas de los grupo étnicos, en ciertos indios geográficos que constituyen el habitat de los mismos, e incluso en prejuicios que se nutren de un marcado europocentrismo.

  2. Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

    Cai, X.Z. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Huang, W.Y.; Qiao, Y.; Chen, Y.; Du, S.Y.; Chen, D.; Yu, S. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Liu, N. [Department of Nephrology, First Affiliated Hospital, China Medical University, Shenyang (China); Dou, L.Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Jiang, Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Department of Dermatology, First Affiliated Hospital, China Medical University, Shenyang (China)

    2014-10-17

    The T-cell immunoglobulin and mucin domain (TIM) family is associated with autoimmune diseases, but its expression level in the immune cells of systemic lupus erythematosus (SLE) patients is not known. The aim of this study was to investigate whether the expression of TIM-3 mRNA is associated with pathogenesis of SLE. Quantitative real-time reverse transcription-polymerase chain reaction analysis (qRT-PCR) was used to determine TIM-1, TIM-3, and TIM-4 mRNA expression in peripheral blood mononuclear cells (PBMCs) from 132 patients with SLE and 62 healthy controls. The PBMC surface protein expression of TIMs in PBMCs from 20 SLE patients and 15 healthy controls was assayed by flow cytometry. Only TIM-3 mRNA expression decreased significantly in SLE patients compared with healthy controls (P<0.001). No significant differences in TIM family protein expression were observed in leukocytes from SLE patients and healthy controls (P>0.05). SLE patients with lupus nephritis (LN) had a significantly lower expression of TIM-3 mRNA than those without LN (P=0.001). There was no significant difference in the expression of TIM-3 mRNA within different classes of LN (P>0.05). Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (r{sub s}=0.283, P=0.049) and serum albumin (r{sub s}=0.297, P=0.047). TIM-3 mRNA expression was weakly correlated with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI; r{sub s}=-0.272, P=0.032). Our results suggest that below-normal expression of TIM-3 mRNA in PBMC may be involved in the pathogenesis of SLE.

  3. Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

    The T-cell immunoglobulin and mucin domain (TIM) family is associated with autoimmune diseases, but its expression level in the immune cells of systemic lupus erythematosus (SLE) patients is not known. The aim of this study was to investigate whether the expression of TIM-3 mRNA is associated with pathogenesis of SLE. Quantitative real-time reverse transcription-polymerase chain reaction analysis (qRT-PCR) was used to determine TIM-1, TIM-3, and TIM-4 mRNA expression in peripheral blood mononuclear cells (PBMCs) from 132 patients with SLE and 62 healthy controls. The PBMC surface protein expression of TIMs in PBMCs from 20 SLE patients and 15 healthy controls was assayed by flow cytometry. Only TIM-3 mRNA expression decreased significantly in SLE patients compared with healthy controls (P<0.001). No significant differences in TIM family protein expression were observed in leukocytes from SLE patients and healthy controls (P>0.05). SLE patients with lupus nephritis (LN) had a significantly lower expression of TIM-3 mRNA than those without LN (P=0.001). There was no significant difference in the expression of TIM-3 mRNA within different classes of LN (P>0.05). Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (rs=0.283, P=0.049) and serum albumin (rs=0.297, P=0.047). TIM-3 mRNA expression was weakly correlated with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI; rs=-0.272, P=0.032). Our results suggest that below-normal expression of TIM-3 mRNA in PBMC may be involved in the pathogenesis of SLE

  4. An assessment of beaked redfish (S. mentella and S. fasciatus) in NAFO division 3M (with an approach to the likely impact of recent 3M cod growth on redfish natural mortality)

    Ávila de Melo, A.; SABORIDO-REY Fran; González-Troncoso, Diana; Pochtar, Maria; Alpoim, R. (Ricardo)

    2011-01-01

    The 3M redfish assessment is focused on the beaked redfish, regarded as a management unit composed of two populations from two very similar species: the Flemish Cap S. mentella and S. fasciatus. The reason for this approach is the historical dominance of this group in the 3M redfish commercial catch until 2005. However a new golden redfish fishery (S. marinus) started on September 2005 on shallower depths of the Flemish Cap bank above 300m. This new reality implied a revision of c...

  5. La trasferencia de tecnología en la UC3M: Centros Mixtos de I+D+i

    Hernán Gómez, Miguel

    2011-01-01

    La creación de los centros para la innovación en la Universidad Carlos III de Madrid promueve plataformas comunes de investigación y desarrollo entre la UC3M, las empresas, la administración pública y los usuarios, desarrollando ayudas técnicas, servicios y soluciones innovadoras para la sociedad. El objetivo general de dichos centros es promover plataformas de actuación conjunta entre la UC3M, las empresas y otros agentes sociales, para impulsar los procesos de innovación, generación y trans...

  6. The first results of beam study on C3-1-2. 'MINE' at JRR-3M

    We have constructed new beam-line 'MINE' at the cold neutron guide C3-1-2 of JRR-3M for our multilayer cold neutron interferometer experiments. The 'MINE' employs quadruple (++++) joined multilayer mirrors called 'QUAD' as its monochromator. The 'QUAD' supplies monochromatized long wave length (≥12A) neutron beam. This beam is also available for neutron reflectometers. (author)

  7. Decrease of FOXP3 mRNA in CD4~+ T cells in latent autoimmune diabetes in adult

    杨治芳

    2006-01-01

    Objective To study the percentage of peripheral blood CD4+ CD25+ T cells and the expression of F0XP3 mRNA in patients with latent autoimmune diabetes in adult (LADA). Methods Fresh peripheral blood samples were obtained from 60 patients with LADA,30 patients with type 2 diabetes and 30 age- and sex-matched

  8. Rhythmic control of mRNA stability modulates circadian amplitude of mouse Period3 mRNA.

    Kim, Sung-Hoon; Lee, Kyung-Ha; Kim, Do-Yeon; Kwak, Eunyee; Kim, Seunghwan; Kim, Kyong-Tai

    2015-03-01

    The daily oscillations observed in most living organisms are endogenously generated with a period of 24 h, and the underlying structure of periodic oscillation is an autoregulatory transcription-translation feedback loop. The mechanisms of untranslated region (UTR)-mediated post-transcriptional regulation (e.g., mRNA degradation and internal ribosomal entry site (IRES)-mediated translation) have been suggested to fine-tune the expression of clock genes. Mouse Period3 (mPer3) is one of the paralogs of Period gene and its function is important in peripheral clocks and sleep physiology. mPer3 mRNA displays a circadian oscillation as well as a circadian phase-dependent stability, while the stability regulators still remain unknown. In this study, we identify three proteins - heterogeneous nuclear ribonucleoprotein (hnRNP) K, polypyrimidine tract-binding protein (PTB), and hnRNP D - that bind to mPer3 mRNA 3'-UTR. We show that hnRNP K is a stabilizer that increases the amplitude of circadian mPer3 mRNA oscillation and hnRNP D is a destabilizer that decreases it, while PTB exhibits no effect on mPer3 mRNA expression. Our experiments describe their cytoplasmic roles for the mRNA stability regulation and the circadian amplitude formation. Moreover, our mathematical model suggests a mechanism through which post-transcriptional mRNA stability modulation provides not only the flexibility of oscillation amplitude, but also the robustness of the period and the phase for circadian mPer3 expression. Mouse Period3 (mPer3) is one of well-known clock genes. We identified three 3'-UTR-binding proteins that modulate the mRNA stability, and they influenced to the amplitude of circadian mPer3 mRNA oscillation. Our mathematical model not only showed the relationship between mRNA stability and its oscillation profile but provided the molecular mechanism for the robustness of the period and the phase in circadian oscillation. hnK, heterogeneous nuclear ribonucleoprotein (hnRNP) K; hnD, hn

  9. Lizonia baldini sobre Polytrichum formosum

    Girbal i Lladó, Josep; Lloret Maya, Francisco; Pérez Obiol, Ramon

    1982-01-01

    S'ha trobat al Montseny (UTM:DG 46 26) l'ascomicet briofil Lizonia baldini (Pir) Dobb (Ordre Dothideales) parasit sobre Polytrichum formosum Hedw. Es descriuen les característiques dels exemplars observats i s'indica la seva incidencia en la producció d'anteridis

  10. Discurso sobre la historia colombiana

    Quijano Otero, José María

    2010-01-01

    Resumen de las lecciones de Historia Patria, desde la llegada de Colón hasta los primeros brotes independentistas. Sobre la manera de estudiar los hechos históricos: su enlace, las causas que los produjeron, i los efectos que de ellos derivaron.

  11. Visiones educativas sobre los MOOC

    Cabero Almenara, Julio

    2015-01-01

    Los “Cursos Masivos en Abiertos” o MOOC se están convirtiendo en una de las tecnologías de gran penetración en el terreno educativo en los últimos tiempos, considerándose por algunos como una tecnología que creará un tsunami sobre la educación

  12. On the multi-index (3m-parametric) Mittag-Leffler functions, fractional calculus relations and series convergence

    Paneva-Konovska, Jordanka

    2013-10-01

    In this paper we consider a family of 3m-indices generalizations of the classical Mittag-Leffler function, called multi-index (3m-parametric) Mittag-Leffler functions. We survey the basic properties of these entire functions, find their order and type, and new representations by means of Mellin-Barnes type contour integrals, Wright pΨq-functions and Fox H-functions, asymptotic estimates. Formulas for integer and fractional order integration and differentiations are found, and these are extended also for the operators of the generalized fractional calculus (multiple Erdélyi-Kober operators). Some interesting particular cases of the multi-index Mittag-Leffler functions are discussed. The convergence of series of such type functions in the complex plane is considered, and analogues of the Cauchy-Hadamard, Abel, Tauber and Littlewood theorems are provided.

  13. Tuning of the Thermoelectric Figure of Merit of CH$_3$NH$_3$MI$_3$ (M=Pb,Sn) Photovoltaic Perovskites

    Mettan, Xavier; Pisoni, Riccardo; Matus, Péter; Pisoni, Andrea; Jaćimović, Jaćim; Náfrádi, Bálint; Spina, Massimo; Pavuna, Davor; Forró, László; Horváth, Endre

    2015-01-01

    The hybrid halide perovskites, the very performant compounds in photovoltaic applications, possess large Seebeck coefficient and low thermal conductivity making them potentially interesting high figure of merit ($ZT$) materials. For this purpose one needs to tune the electrical conductivity of these semiconductors to higher values. We have studied the CH$_3$NH$_3$MI$_3$ (M=Pb,Sn) samples in pristine form showing very low $ZT$ values for both materials; however, photoinduced doping (in M=Pb) a...

  14. Fermi level tuning in (Y1-yMy)1-xUxPd3 (M=Th, La)

    The effects of the increase of the U 5f binding energy and the decrease in the localized U 5f electron-conduction electron hybridization on the Kondo temperature, with U intersite interactions held constant to first approximation, are under investigation by means of electrical resistivity, magnetic susceptibility, and specific heat as a function of y for fixed values of x in the (Y1-yMy)1-xUxPd3 (M=Th, La) systems. ((orig.))

  15. Engineered proteins with Pumilio/fem-3 mRNA binding factor scaffold to manipulate RNA metabolism.

    Wang, Yang; Wang, Zefeng; Tanaka Hall, Traci M

    2013-08-01

    Pumilio/fem-3 mRNA binding factor proteins are characterized by a sequence-specific RNA-binding domain. This unique single-stranded RNA recognition module, whose sequence specificity can be reprogrammed, has been fused with functional modules to engineer protein factors with various functions. We summarize the advances made with respect to developing RNA regulatory tools, as well as opportunities for the future. PMID:23731364

  16. Separation of isotope mixtures of molecular hydrogen on NaX-3M zeolite. 2. Isotopic equilibrium

    Isotopic equilibrium in the molecular hydrogen-NaX-3M zeolite system was investigated. Sorption isotherms of H2, D2, HD, HT, DT, T2 on zeolite were used to calculate the dependencies of binary factors of separation of isotope mixtures of molecular hydrogen on temperature (30-100 K) and pressure (0.25x105-1x107 Pa), which were compared with experimentally obtained results. Satisfactory agreement of experimental and calculation data was obtained

  17. Room temperature syntheses and thermal behaviors of hydrogarnets Sr3M2(OH)12 (M = Al, Cr and Fe)

    Highlights: • All starting materials were common metal inorganic salts. • Hydrogarnets were synthesized by solid state reaction at room temperature. • The novel synthesis method has an advantage of quick reaction and easy operation. • As-synthesized hydrogarnets have different morphologies. - Abstract: Hydrogarnets Sr3M2(OH)12 (M = Al, Cr and Fe) were synthesized through a solid state reaction at room temperature with Al(NO3)3·9H2O, CrCl3·6H2O, FeCl3·6H2O, Sr(NO3)2 and NaOH as the starting materials. All X-ray diffraction (XRD) data of Sr3M2(OH)12 were indexed by the cubic system with the space group of Ia−3d. XRD, differential thermal analysis and thermogravimetric (DTA–TG), and scanning electron microscopy (SEM) were employed to investigate the structural stability, thermal properties and morphologies of Sr based hydrogarnets. The cause of room temperature synthesis and the thermal decomposition behaviors of Sr-based hydrogarnets Sr3M2(OH)12 (M = Al, Cr and Fe) are discussed

  18. Design of multichord Hα detector arrays for the U-3M torsatron and identification of rotating plasma perturbations

    Dreval, M. B.; Shapoval, A. M.; Ozherelyev, F. I.; Makhov, M. M.

    2016-07-01

    An Hα camera has been designed and installed in the U-3M torsatron for spatially and temporally resolved measurements. This device provides fast measurements of the emission brightness profile in the noisy environment of the radio frequency (RF) heated plasma. Unusual topology of diagnostics and the data acquisition system are applied. All the system components, including digitizers, are assembled in a single unit. It allows the suppression of a low-frequency electromagnetic interference by eliminating the ground loops. And the suppression of RF noises is achieved by eliminating the signal interface cables and digital interface cables in the design. The Wi-Fi interface is used to prevent a ground loop in the data transfer stage. The achieved sensitivity of our diagnostics is high enough for measuring the Hα emission from the low-density (ne ≈ (1-2)ṡ1010 cm-3) plasma with a temporal resolution of about 20 μs in the noisy environment. Different types of Hα emission fluctuations within the frequency range of 1-5 kHz and poloidal mode numbers m = 0 and m = 5 have been observed in U-3M. A simple technique of the line-of-sight data analysis, based on the U-3M magnetic surface asymmetry, is proposed and used for the spatial localization of the rotating mode and for the determination of mode numbers and its poloidal rotation direction using a single Hα array.

  19. SF3M 2.0: improvement of 3D photo-reconstruction interface based on freely available software

    Castillo, Carlos; James, Michael R.; Pérez, Rafael; Gómez, Jose A.

    2016-04-01

    During recent years, a number of tools based on Structure-from-Motion algorithms have been released for full image-based 3D reconstruction either freely (e.g. Bundler, PMVS2, VisualSFM, MicMac) or commercially (e.g. Agisoft PhotoScan). The SF3M interface was developed in Matlab® to use link software developments (VisualSFM, CloudCompare) and new applications to create a semi-automated workflow including reconstruction, georeferencing and point-cloud filtering, and has been tested for gully erosion assessment with terrestrial images (Castillo et al., 2015). The main aim of this work to provide an improved freely-available and easy-to-use alternative for 3D reconstruction intended for public agencies, non-profit organisations, researchers and other stakeholders interested in 3D modelling. In this communication we present SF3M 2.0, a new version of the graphical user interface. In this case, the SfM module is based on MicMac, an open-software tool (Pierrot-Deseilligny and Cléry, 2011) which provides advanced features such as camera calibration and constrained bundle adjustment using ground control points. SF3M 2.0 will be tested in two scenarios: a) using the same ground-based image set tested in Castillo et al. (2015) to compare the performance of both versions and b) using aerial images taken from a helium balloon to assess a gully network in a 40-hectares catchment. In this study we explore the advantages of SF3M 2.0, explain its operation and evaluate its accuracy and performance. This tool will be also available for free download. References Castillo, C., James, M.R., Redel-Macías, M. D., Pérez, R., and Gómez, J.A.: SF3M software: 3-D photo-reconstruction for non-expert users and its application to a gully network, SOIL, 1, 583-594. Pierrot-Deseilligny, M and Cléry, I. APERO, an Open Source Bundle Adjusment Software for Automatic Calibration and Orientation of a Set of Images. Proceedings of the ISPRS Commission V Symposium, Image Engineering and Vision

  20. Clinical significance of expression of Foxp3 mRNA in patients with asthma%哮喘患者外周血转录因子Foxp3mRNA表达水平及临床意义

    谭楠

    2012-01-01

    目的:探讨哮喘患者外周血叉头翼状螺旋转录因子3(Foxp3)mRNA表达水平及临床意义.方法:采用实时荧光定量PCR技术检测63例哮喘患者和40例正常对照组外周血中转录因子Foxp3 mRNA表达水平.结果:哮喘组患者外周血Foxp3 mRNA表达水平(0.32±0.13)较对照组(1.15±0.31)明显降低,差异有统计学意义(P<0.05);急性发作期患者外周血Foxp3 mRNA表达水平(0.22±0.06)较非急性发作期患者(0.47±0.15)明显降低,差异有统计学意义(P<0.05);急性发作期重度患者外周血Foxp3 mRNA表达水平(0.18±0.04)较对照组(0.29±0.07)明显降低,差异有统计学意义(P<0.05).结论:哮喘患者外周血中转录因子Foxp3 mRNA表达水平明显降低且与疾病分期及病情严重程度密切相关,Foxp3可能参与了哮喘发病过程.%Objective:To explore the expression of Foxp3 Mrna in peripheral blood from patients with asthma and its clinical significance. Methods: 63 patients with asthma and 40 controls were enrolled. The expressions of Foxp3 Mrna were analyzed by real-time PCR. Results:The Mrna levels of Foxp3 in peripheral blood from patients with asthma (0. 32 ± 0. 13) were significantly decreased. There were significantly different between the experimental group and control group (1. 15 ± 0. 31) (P <0. 05). The Mrna levels of Foxp3 in in peripheral blood from patients during acute phase (. 22 ± 0. 06) were in patients during chronic phase (0. 47+0. 15). The Mrna levels of Foxp3 in severe group (0. 18 ± 0. 04) were significantly decreased. There were significantly different between the severe group and slight, moderate group (0. 29 ± 0. 07) (P <0. 05). Conclusion:The Mrna levels of Foxp3 in peripheral blood from patients with asthma are significantly decreased and have association with disease stages and disease severity. Foxp3 may participate in the development of asthma.

  1. First-order ion-optics calculations for an Accelerator Mass Spectrometry system using SRIM and S3M

    In this paper, we describe the transport of a simulated beam, created with the S3M beam generation module, along the real beam line of the Accelerator Mass Spectrometry (AMS) facility located at Centro Nacional de Aceleradores (CNA, Seville, Spain). The beam transport through the optical system was determined using the transfer-matrix method, which can easily calculate the beam envelopes without having to track all individual particles, evaluating the ability of such systems and saving computation time. The beam size results given by S3M were compared to the real beam size in three of the four image points that the system has (P1, P2 and P3), corresponding with the position of Faradays Cups where the 127I current was measured, obtaining a good agreement between them. This suggests that the first order approximation model is enough to simulate the optical behavior of the system. It is shown that the beam line has a focusing behavior, minimizing the beam size from ±3 mm at the exit of the ion source to ±1.09 mm at the detector’s entrance window. Using the beam emittance diagram simulations, it is shown that when ions pass through the stripper, the angles of their trajectories are altered by scattering with the gas molecules and the geometrical emittance enlarges, according to Liouville’s Theorem. The study presented in this work gives confidence and open new perspectives in simulations with S3M in AMS facilities contributing to the understanding of their optical behavior.

  2. Bolt study - behaviour of bolts in drop accident scenarios of the Nirex 3m3 Box ILW package

    The mission of Nirex is to provide the UK with safe, environmentally sound and publicly acceptable options for the long-term management of radioactive materials. One of the key tasks is to ensure that waste is packaged by waste producers in a form which is suitable for safe storage, transport, handling and potential disposal. In pursuit of this key requirement, Nirex has developed specifications to set the standard for the design and performance of waste packages, and has developed standard containers for the packaging of intermediate level (ILW) and some low level waste (LLW) - one of these is the 3m3 Box for immobilised operational and decommissioning ILW. The dimension envelope of this package is 1716 mm x 1716 mm in plan with 430 mm corner radii, 1226 mm tall. The maximum loaded weight is 12 tonnes. A generic design of this container has been developed, which is a welded structure manufactured from austenitic stainless steel (EN 10088-2 steel number 1.4404). The lid is connected to the body by 28 stainless steel bolts. An extensive study was carried out to develop a robust FE model of the bolts. The specific focus of this work was to use improved bolt modelling to optimize the design of the 3m3 Box, although this work could be applied to other bolted containers. This paper presents a summary of the findings from the study as follows: 1. Development of a FE bolt model for application in a 3m3 Box model. 2. Development and execution of a bolt testing programme which included tensile and shear tests on a total of 88 bolts, representing four grades of stainless steel materials, three thread sizes, and two geometries at three strain rates. 3. Benchmarking of the FE bolt model that can be used with confidence in simulating waste package behaviour in drop scenarios

  3. Bolt study - behaviour of bolts in drop accident scenarios of the Nirex 3m{sup 3} Box ILW package

    Turner, G. [United Kingdom Nirex Ltd., Harwell (United Kingdom); Tso, C.F. [Arup, London (United Kingdom)

    2004-07-01

    The mission of Nirex is to provide the UK with safe, environmentally sound and publicly acceptable options for the long-term management of radioactive materials. One of the key tasks is to ensure that waste is packaged by waste producers in a form which is suitable for safe storage, transport, handling and potential disposal. In pursuit of this key requirement, Nirex has developed specifications to set the standard for the design and performance of waste packages, and has developed standard containers for the packaging of intermediate level (ILW) and some low level waste (LLW) - one of these is the 3m{sup 3} Box for immobilised operational and decommissioning ILW. The dimension envelope of this package is 1716 mm x 1716 mm in plan with 430 mm corner radii, 1226 mm tall. The maximum loaded weight is 12 tonnes. A generic design of this container has been developed, which is a welded structure manufactured from austenitic stainless steel (EN 10088-2 steel number 1.4404). The lid is connected to the body by 28 stainless steel bolts. An extensive study was carried out to develop a robust FE model of the bolts. The specific focus of this work was to use improved bolt modelling to optimize the design of the 3m{sup 3} Box, although this work could be applied to other bolted containers. This paper presents a summary of the findings from the study as follows: 1. Development of a FE bolt model for application in a 3m{sup 3} Box model. 2. Development and execution of a bolt testing programme which included tensile and shear tests on a total of 88 bolts, representing four grades of stainless steel materials, three thread sizes, and two geometries at three strain rates. 3. Benchmarking of the FE bolt model that can be used with confidence in simulating waste package behaviour in drop scenarios.

  4. Design and performance estimate of a focal reducer for the 2.3 m Thai National Telescope.

    Buisset, Christophe; Deboos, Alexis; Lépine, Thierry; Poshyachinda, Saran; Soonthornthum, Boonrucksar

    2016-01-25

    We have designed a new kind of focal reducer for the 2.3 m Thai National Telescope (TNT) to image the TNT specified FOV Δθ = 14.6' with an angular resolution α ≈1.2 arcsec. This, at a minimum cost by using common glasses, spherical surfaces and by requiring comfortable mechanical tolerance. This focal reducer comprises 1 lens placed at the level of the fork entrance and 1 lens placed in front of the detector. In this paper, we present the focal reducer paraxial model, we describe the optical design and we present the performance. PMID:26832523

  5. MRI of the lung using hyperpolarized He-3 at very low magnetic field (3 mT)

    Bidinosti, C P; Tastevin, G; Vignaud, A; Nacher, P J

    2004-01-01

    Optical pumping of He-3 produces large (hyper) nuclear-spin polarizations independent of the magnetic resonance imaging (MRI) field strength. This allows lung MRI to be performed at reduced fields with many associated benefits, such as lower tissue susceptibility gradients and decreased power absorption rates. Here we present results of 2D imaging as well as accurate 1D gas diffusion mapping of the human lung using He-3 at very low field (3 mT). Furthermore, measurements of transverse relaxation in zero applied gradient are shown to accurately track pulmonary oxygen partial pressure, opening the way for novel imaging sequences.

  6. Structural, electronic and optical properties of Li intercalated on MO3 (M: Mo, W): A first principle investigation

    Mahmoudi, A.; Faraoun, H. I.; Benabadji, M. K.; Abdellaoui, I.; Dergal, M.

    2016-03-01

    The correlations between electronic and optical properties of pure MO3 (M=Mo, W) and the effect of Li intercalated in the matrix are investigated within density functional theory using both the revised gradient-corrected Perdew-Burke-Ernzerhof (GGA-PBE), GGA+U and HSE06 functional frameworks along with ab initio pseudopotentials method. Calculation performed with HSE06 functional proves that all these compounds are wide band gap semiconductors. The energy gap value is found to decrease with lithium incorporation, affecting the visible absorption coefficients.

  7. Extension of Studies with 3M Empore TM and Selentec MAG *SEP SM Technologies for Improved Radionuclide Field Sampling

    Beals, D.M. [Westinghouse Savannah River Company, AIKEN, SC (United States); Bibler, J.P.; Brooks, D.A.

    1996-07-10

    The Savannah River Technology Center is evaluating new field sampling methodologies to more easily determine concentrations of radionuclides in aqueous systems. One methodology studied makes use of 3M EmporeTM disks. The disks are composed of selective resins embedded in a Teflon support. The disks remove the ion of interest from aqueous solutions when the solution is passed through the disk. The disk can then be counted directly to quantify the isotope of interest. Four types of disks were studied during this work: for the extraction of technetium (two types), cesium, plutonium, and strontium. A sampler has been developed for automated, unattended, in situ use of the EmporeTM disks.

  8. FABRICATION OF A 3 m Ø x 5 m SUPERCONDUCTING SOLENOID FOR THE FERMILAB COLLIDER DETECTOR FACILITY

    Minemura, H.; Mori, S.; Yoshizaki, R.; Kondo, K.(Yamagata University, Yamagata, 992-8510, Japan); Fast, R; Kephart, R.; Wands, R.; Yamada, R.

    1984-01-01

    The 3mØ x 5m (1.5 Tesla) superconducting solenoid for the Fermilab Collider Detector Facility (CDF) is under construction in Japan. The coil consists of a single layer aluminum-stabilized monolithic NbTi/Cu superconductor fabricated with the EFT (extrusion with front tension) method. The forced flow cooling method of two-phase helium is used. In order to minimize the material thickness of the solenoid the coil is built without a permanent inner bobbin. The radial electromagnetic forces are su...

  9. Extension of Studies with 3M Empore TM and Selentec MAG *SEP SM Technologies for Improved Radionuclide Field Sampling

    The Savannah River Technology Center is evaluating new field sampling methodologies to more easily determine concentrations of radionuclides in aqueous systems. One methodology studied makes use of 3M EmporeTM disks. The disks are composed of selective resins embedded in a Teflon support. The disks remove the ion of interest from aqueous solutions when the solution is passed through the disk. The disk can then be counted directly to quantify the isotope of interest. Four types of disks were studied during this work: for the extraction of technetium (two types), cesium, plutonium, and strontium. A sampler has been developed for automated, unattended, in situ use of the EmporeTM disks

  10. Mutual transformation of light waves by reflection holograms in photorefractive crystals of the 4-bar 3m symmetry

    Naunyka, V. N.; Shepelevich, V. V., E-mail: vasshep@inbox.ru [Mozyr State Pedagogical University (Belarus)

    2011-05-15

    The mutual transformation of light waves in the case of their simultaneous diffraction from a bulk reflection phase hologram, which was formed in a cubic photorefractive crystal of the 4-bar 3m symmetry class, has been studied. The indicator surfaces of the polarization-optimized values of the relative intensity of the object wave, which make it possible to determine the amplification of this wave for any crystal cut, are constructed. The linear polarization azimuths at which the energy exchange between the light waves reaches a maximum are found numerically for crystals of different cuts.

  11. Interactions among three proteins that specifically activate translation of the mitochondrial COX3 mRNA in Saccharomyces cerevisiae.

    Brown, N.G.; Costanzo, M. C.; Fox, T D

    1994-01-01

    The PET54, PET122, and PET494 proteins, which are associated with the yeast inner mitochondrial membrane, specifically activate translation of the mitochondrially encoded COX3 mRNA. We used the two-hybrid system to test whether pairs of these proteins, when fused to either the GAL4 DNA-binding or transcriptional activating domain, can physically associate as measured by the expression of the GAL4-dependent reporter, lacZ. PET54 and PET122 interacted in this system, and an amino-terminally tru...

  12. OBSL1 mutations in 3-M syndrome are associated with a modulation of IGFBP2 and IGFBP5 expression levels

    Huber, Celine; Fradin, Mélanie; Edouard, Thomas; Le Merrer, Martine; Alanay, Yasemin; Da Silva, Daniela Bezerra; David, Albert; Hamamy, Hanan; van Hest, Liselotte; Lund, Allan M; Michaud, Jacques; Oley, Christine; Patel, Chirag; Rajab, Anna; Skidmore, David L; Stewart, Helen; Tauber, Maité; Munnich, Arnold; Cormier-Daire, Valerie

    2010-01-01

    3-M syndrome is an autosomal recessive disorder characterized by severe pre- and postnatal growth retardation and minor skeletal changes. We have previously identified CUL7 as a disease-causing gene but we have also provided evidence of genetic heterogeneity in the 3-M syndrome. By homozygosity m...... mutations (p.F697G; p.H814RfsX15). We found normal CUL7 mRNA levels but abnormal IGFBP2 and IGFBP5 mRNA levels in the two patients, suggesting that OBSL1 modulates the expression of IGFBP proteins....... mapping in two inbred families, we found a second disease locus on chromosome 2q35-36.1 in a 5.2-Mb interval that encompasses 60 genes. To select candidate genes, we performed microarray analysis of cultured skin fibroblast RNA from one patient, looking for genes with altered expression; we found...... decreased expression of IGFBP2 and increased expression of IGFBP5. However, direct sequencing of these two genes failed to detect any anomaly. We then considered other candidate genes by their function/location and found nine distinct mutations in the OBSL1 gene in 13 families including eight nonsense and...

  13. PARTICIPAÇÃO DO CONSUMIDOR NO DESENVOLVIMENTO DO SISTEMA LINUX: APLICAÇÃO DO 3M DE MOWEN

    Alexandre Eugenio Pieske

    2012-03-01

    Full Text Available Este trabalho investiga o prosumidor, indivíduo parte produtor, parte consumidor. Para entender seu comportamento, selecionou-se o 3M (Modelo Metateórico de Motivação e Personalidade, de Mowen (2000, adaptado por Monteiro (2006, que interpreta o comportamento do consumidor por traços de personalidade. O objeto de estudo são prosumidores do Linux, já que este sistema operacional possibilita livre modifi cação. Foi realizada pesquisa em duas etapas: qualitativa preparatória e quantitativa, para testar a aplicação do modelo. Foram realizadas entrevistas individuais com usuários Linux, resultando na identifi cação de cinco níveis de participação. Na segunda fase, foi aplicado um survey, pela Internet, a membros de comunidades Linux. Por meio de modelagem em equações estruturais, o 3M foi aplicado, fazendo-se os devidos ajustes. Apesar de os coefi cientes de determinação terem sido signifi cativos, alguns índices de ajuste apresentaram-se baixos.

  14. STUDY OF MORPHOLOGICAL CHANGES OF HEART IN VIRAL MYOCARDITIS CAUSED BY REPETITIVE INFECTION OF CVB3m

    2006-01-01

    Objective To investigate the morphological changes of heart in viral myocarditis caused by repetitive infection of CVB3m. Methods 4-week-old mice were infected four times intraperitoneally with a timedependent dose and killed at the 10th,30th and 60th day after the final infection respectively, then we examined the heart changes and collagen hyperplasia by HE, VG stain and IHC. Results Heart damage appeared very serious at the tenth day, even there were small necrotic foci at the day of 30th, but we could not see any injury of heart 2 months later after final infection. Collagen turned up at the tenth day and there was much more collagen in heart and increased PCVA, CVF index at the sixtieth day. The IHC of collagen demonstrated the collagen Ⅰ hyperplasia was much obvious compared to collagen Ⅲ. Conclusion It strongly indicated that repetitive infection of CVB3m could lead to heart fibrosis and ventricular remodeling, which resulted in decreased systolic and diastolic function of heart.

  15. SNaPshot技术检测Y-SNP位点O3-M122单倍群的应用%The application of Y-SNP genotyping by SNaPshot assay under the O3-M122 haplogroup

    孙亚男; 李安; 史斌; 董庆旭; 李貌; 何玮; 翟滇; 程宝文

    2013-01-01

    目的 采用SNaPshot技术检测案例检材O3-M122位点6个亚群的分型,并调查其在云南3个民族无关男性人群中的频率分布.方法 建立5-plex Y-SNPs复合扩增体系,采用SNaPshot Multiplex试剂盒,检测案例检材O3-M122单倍群下O3*-M122、O3a*-M324、O3a3*-P201、O3a3b*-M7、O3a3c*-M134、O3a3c1*-M117共6个Y-SNPs分型,并对上述6个Y-SNPs在云南佤族、白族、傣族共174名无关男性个体中的分布进行调查.结果 17份案例检材均得到良好的分型结果.上述3个民族分别在3个、5个、5个位点上发现多态性,其中佤族O3a3*-P201分布频率最高(0.430 0);白族O3a*-M324频率最高(0.2123);傣族O3a3c1*-M117频率最高(0.158 2).结论 多重PCR反应及SNaPshot技术的联合应用适用于法医案件检材DNA检测,3个民族多态性数据可为相关应用所参考.

  16. Measurements of radiation exposure on commercial aircraft with the LIULIN-3M instrument; Mesure de l'exposition aux radiations sur les vols commerciaux avec l'equipement LIULIN-3M

    Stassinopoulos, E.G. [NASA Centre des Vols Spatiaux Goddard, Greenbelt, MD (United States); Stauffer, C.A. [Stinger Gaffarian Technologies, Greenbelt, MD (United States); Dachev, T.P.; Tomov, B.T.; Dimitrov, P.G. [Academie des Sciences, Bulgarie, Lab. d' Etudes des Influences Soleil-Terre, Sofia (Bulgaria); Brucker, G.J. [Radiation Effects Consultants, Inc., West Long Branch, NJ (United States)

    1999-07-01

    The LIULIN-3M evolved from an international cooperative project by a group of Bulgarian, Russian, German, and American scientists. The radiometer is a low power, small size, light weight, and low cost instrument composed of a solid state detector (SSD) with supporting electronics that enable it to operate as a pulse height analyzer of energy deposited in the detector, and to obtain from these measurements the total dose or the dose rate produced by charged particles. The instrument has also been used as a low-LET radiation spectrometer for measuring biological doses of potential human exposures. A flash memory allows self-storage of data during flights and post flight retrieval. Results will be presented and discussed. (author)

  17. Phycocyanin for protecting brain ischemia-reperfusion injury and its effect on the expression of Caspase-3 mRNA

    Xuewei Yang; Yunliang Guo; Hongbing Chen

    2006-01-01

    BACKGROUND: Phycocyanin can anti-oxidize and clear free radial. Whether its protective effect on brain is related to Caspase-3, the promoter and operator of apoptosis, is highly concerned.OBJECTIVE: To observe phycocyanin for protecting nerve function and reducing the size of cerebral infarction of rats with brain ischemia-reperfusion and its effect on the expression of Caspase-3 mRNA.DESIGN: A randomized controlled experiment.SETrING: Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University.MATERIALS: Totally 84 adult healthy female Wistar rats, weighing 210 to 250 g, of clean grade, were provided by the Animal Experimental Center of Shandong University. Phycocyanin (Institute of Oceanography of Chinese Academy of Sciences) was used.METHODS: This experiment was carried out in the Key Laboratory for Prevention and Treatment of Brain Diseases during May to December 2005. ① The rats were randomized into sham-operation group (n=4),control group (n=40) and phycocyanin-treated group (n=40). Middle cerebral artery occlusion/reperfusion (MACO/R) models were created on the rats of control and phycocyanin-treated groups with suture-occluded method by inserting a thread into left side external-internal carotid artery. In the sham-operation group, inserting suture was omitted. After ischemia for 1 hour and reperfusion for 2 hours, suspension of phycocyanin was intragastrically administrated into the rats of the phycocyanin-treated group at 100 mg/kg , and the same volume of normal saline was isochronously administrated into the rats of control group as the same. ② Six rats were chosen respectively from the control group and phycocyanin-treated group, then neurologic impairment degrees of rats were evaluated according to Bederson's grading. ③ Six rats were chosen respectively from the control and phycocyanin-treated groups. The isolated brain tissue was stained with triphenyltetrazolium chloride, and then the size of cerebral

  18. Modelos ambientales sobre la vejez

    Izal, María; Fernández-Ballesteros, Rocío

    1990-01-01

    La perspectiva ambiental en el estudio de la vejez es probablemente un ámbito poco conocido. En este trabajo se expone una revisión crítica de los principales modelos de explicación de las relaciones ambiente-conducta en la vejez. Finalmente, se discute sobre la superación de algunas limitaciones presentes en estas formulaciones teóricas, presentándose posibles alternativas teóricas y metodológicas para el desarrollo de esta área.

  19. COMENTARIOS SOBRE MEMORIA Y COMUNIDAD

    José A. Escalona Delfino

    2009-01-01

    El presente trabajo es una reflexión sobre aspectos esenciales en torno a la relación memoria-comunidad y su importancia para la investigación científica de las sociedades y los grupos humanos. Sin penetrar en profundidad en la trayectoria histórica del tema, ni en el tratamiento específico que importantes hombres de ciencia, considerados sus progenitores o procreadores, han dado a estos conceptos, hacemos particulares consideraciones con respecto al concepto de Memoria Histórica o Colectiva....

  20. Nota sobre Keynes y Brentano

    Crespo, Ricardo F.; IAE (Universidad Austral) y CONICET

    2013-01-01

    Este trabajo explora la posibilidad de una relación entre el pensamiento de John Maynard Keynes y el del filósofo alemán Franz Brentano (1839-1917) en los campos lógico y epistemológico. George E. Moore -profesor de Keynes- y Keynes mismo leyeron y alabaron el libro de Brentano El origen del conocimiento moral (1889). ¿Tomó Keynes algunas ideas lógicas o epistemológicas de Brentano? El trabajo sugiere que, a pesar de ciertas similitudes entre las ideas lógicas y sobre la verdad de Keynes y Br...

  1. Historicismo: notas sobre um paradigma

    José D’Assunção Barros

    2012-01-01

    Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX. O primeiro ponto tratado é relativo às origens do paradigma Historicista na transição do século XVIII para o século XIX. Na sequência, aproximamo-nos da apropriação conservadora do paradigma historicista no novo contexto no qual a burguesia européia está assentada no Poder,...

  2. Thomas Hobbes: sobre el miedo

    Carlos Bührle

    2004-01-01

    Este trabajo pretende echar cierta luz sobre el papel del miedo en el pensamiento político de Hobbes. Sabido es que esta pasión subyace al contrato social, en el sentido de que impulsa al hombre a abandonar el estado de naturaleza a fin de encontrar seguridad y de deshacerse de la amenaza de la muerte violenta. Teniendo en cuenta que el miedo y la muerte son inseparables en la filosofía de Hobbes, surge una pregunta fundamental: ¿hasta qué punto podemos decir que el miedo desaparece completam...

  3. Sobre la crisis financiera internacional

    Antonio Torrero Mañas

    2013-01-01

    Este trabajo es una reflexión sobre la crisis financiera internacional en la mitad de su sexto año. Respecto a la evolución de la crisis tengo una sensación agridulce. La parte positiva es que se ha evitado un descalabro inmediato de gran entidad. Mi mayor inquietud procede de los desequilibrios que pueden provocar las finanzas internacionales sin que exista ninguna institución moderadora y ordenadora de los flujos con un ámbito supranacional. Creo que una fuente válida de inspiración serí...

  4. Lumbalgias en hockey sobre cesped

    Rodríguez, Claudia

    2011-01-01

    Se realizó un estudio tomando como muestra a 84 jugadoras de hockey sobre hierba amateurs, mayores de 18 años de la primera categoría de la ciudad de Mar del Plata, en la cual el objetivo general fue determinar la incidencia del gesto deportivo en las lumbalgias de dichas jugadoras. El dolor lumbar tiene una alta prevalencia entre los deportistas, se ha relacionado con déficits en la fuerza extensora lumbar, y el hecho de padecerlo representa un obstáculo importante para la ...

  5. Entorno colaborativo sobre laboratorios remotos

    Grosclaude, Eduardo; Sznek, Jorge Eduardo; Ramos Garcia, Vicente; Bertogna, Mario Leandro; López Luro, Francisco; Zanellato, Claudio

    2006-01-01

    El proyecto de investigación Software para Procesos Colaborativos incluye una línea de acción sobre el desarrollo de experiencias en Laboratorios Remotos. Esta línea está dedicada a complementar las tareas de aprendizaje con un soporte tecnológico de sistemas, entendido como todas aquellas actividades de infraestructura que promuevan la disponibilidad de recursos y apoyen la escalabilidad de procesos en la tarea educativa apuntalada por tecnologías de información. En este trabajo se describe ...

  6. Automated IBM PC/XT/AT based measurement and control system for the DRON-3M X-ray diffractometer

    An automated IBM PC/XT/AT based measurement and control system for the DRON-3M X-ray diffractometer is decribed. The system permits carrying out of real time diffractometer control automatic X-spectra measurement and data acquisition, as well as experimental information computing and representation. The electronic of the system consists of a CAMAC crate with analog and power modules, and a control and measurement organization module, performed as a single bord in the standard of PC electronics. The system provides X-spectra acquisition with volume up to 4K in the angle range from 100 to 160 degrees with a resolution of 0.01 degree, a dead time less than 1mks and an exposition time from tenths of a second to dozens of minutes. 3 refs.; 5 figs

  7. Nonlinear elastic properties of superconducting antiperovskites MNNi 3 (M =Zn, Cd, Mg, Al, Ga, and In) from first principles

    Liu, Lili

    2014-05-22

    We present theoretical studies for the third-order elastic constants (TOECs) of superconducting antiperovskites MNNi 3 (M = Zn, Cd, Mg, Al, Ga, and In) using the density functional theory (DFT) and homogeneous deformation method. From the nonlinear least-square fitting, the elastic constants are extracted from a polynomial fit to the calculated strain-energy data. Calculated second-order elastic constants (SOECs) are compared with the previous theoretical calculations, and a very good agreement was found. The nonlinear effects often play an important role when the finite strains are larger than approximately 2.5 %. Besides, we have computed the pressure derivatives of SOECs and provided rough estimations for the Grüneisen constants of long-wavelength acoustic modes by using the calculated TOECs. © 2014 Springer Science+Business Media New York.

  8. Characteristics of the three-half-turn-antenna-driven RF discharge in the Uragan-3M torsatron

    Grigor’eva, L. I.; Chechkin, V. V., E-mail: chechkin@ipp.kharkov.ua; Moiseenko, V. E.; Grekov, D. L.; Pavlichenko, R. O.; Lozin, A. V.; Tarasov, I. K.; Kulaga, A. Ye.; Zamanov, N. V.; Tretiak, K. K.; Kozulya, M. M.; Beletskii, A. A.; Kasilov, A. A.; Mironov, Yu. K.; Romanov, V. S.; Voitsenya, V. S. [National Science Center Kharkiv Institute of Physics and Technology, Institute of Plasma Physics (Ukraine)

    2015-12-15

    In the ℓ = 3 Uragan-3M torsatron hydrogen plasma is produced by RF fields in the Alfvén range of frequencies (ω ≤ ω{sub ci}). The initial (target) plasma with the line-averaged density of units 10{sup 12} cm{sup −3} is produced by a frame antenna with a broad spectrum of generated parallel wavenumbers. After this, to heat the plasma and bring its density to ∼10{sup 13} cm{sup –3}, another, shorter wavelength three-half-turn antenna with large transverse currents is used. The behavior of the density, electron temperature, and loss of the plasma supported by the three-half-turn antenna is studied depending on the RF power fed to the antenna and initial values of the density and electron temperature supplied by the frame antenna.

  9. The over 3 m long SV25 steel props at an experimental stand and in underground site testing

    Homel, J.; Labonski, S.; Kozlowski, A.

    1991-07-01

    Presents results of an experimental stand and underground tests of installing long SV25 props in over 3 m high workings. Bench tests showed the bearing capacity of 3.5-4.86 m high props to be 285 kN on average for the first stage up to the point of sliding in joints and 160 kN in the second phase after straightening of stirrups. Characteristics of bending tests are also presented. Field tests were conducted in the Moszczenica black coal mine with satisfactory results. The conclusion is reached that props with two stirrups should be used only as auxiliary support reinforcement while application of a third stirrup is recommended if they are used as basic support elements. Application of double-yoke stirrups is also recommended. 3 refs.

  10. Evaluation of the 3M Petrifilm Enterobacteriaceae Count plate method for the enumeration of Enterobacteriaceae in foods.

    Silbernagel, Karen M; Lindberg, Kathryn G

    2002-09-01

    Results of the 3M Petrifilm Enterobacteriaceae Count (EB) plate method were compared with those of the standard violet red bile glucose agar (VRBG) method for the detection and enumeration of Enterobacteriaceae. Studies involving 107 bacterial strains demonstrated that the Petrifilm EB plate method is as sensitive as and more selective than the VRBG method. Sixty of the 62 pure Enterobacteriaceae cultures were recovered by both methods. In addition, 38 of the 45 non-Enterobacteriaceae organisms did not grow on the Petrifilm EB plate, while 28 of the 45 non-Enterobacteriaceae organisms did not grow on the VRBG plate. Colony counts from 174 naturally contaminated and 120 artificially inoculated dairy and nondairy food samples showed that the Petrifilm EB plate method performed as well as or better than the standard VRBG method for the enumeration of Enterobacteriaceae. PMID:12233857

  11. Theoretical prediction of structural, elastic and electronic properties of M5Si3 (M = Ti, Zr) compounds

    Structural, elastic, electronic and mechanical properties of the M5Si3 (M = Ti, Zr) compounds with (Mn5Si3) 16H crystal structure have been studied with respect to pressure. Our computational method is based on a pseudo-potential plane-wave (PP-PW) method. The exchange correlation has been treated using the generalized gradient approximation (GGA) in order to work out the densities of states. Ground-state quantities, such as lattice parameter and bulk modulus, have been evaluated, as well as elastic constants and their pressure derivative. Elastic constants and their pressure dependence have been calculated. Also, bulk and shear moduli, Young' modulus and Poisson's ratio for ideal polycrystalline phases have been derived. (author)

  12. Trends in (LaMnO3)n/(SrTiO3)m superlattices with varying layer thicknesses

    Jilili, J.

    2015-09-01

    We investigate the thickness dependence of the structural, electronic, and magnetic properties of (LaMnO3)n/(SrTiO3)m (n, m = 2, 4, 6, 8) superlattices using density functional theory. The electronic structure turns out to be highly sensitive to the onsite Coulomb interaction. In contrast to bulk SrTiO3, strongly distorted O octahedra are observed in the SrTiO3 layers with a systematic off centering of the Ti atoms. The systems favour ferromagnetic spin ordering rather than the antiferromagnetic spin ordering of bulk LaMnO3 and all show half-metallicity, while a systematic reduction of the minority spin band gaps as a function of the LaMnO3 and SrTiO3 layer thicknesses originates from modifications of the Ti dxy states.

  13. Overview of the O3M SAF GOME-2 operational atmospheric composition and UV radiation data products and data availability

    S. Hassinen

    2015-07-01

    Full Text Available The three GOME-2 instruments will provide unique and long data sets for atmospheric research and applications. The complete time period will be 2007–2022, including the period of ozone depletion as well as the beginning of ozone layer recovery. Besides ozone chemistry, the GOME-2 products are important e.g. for air quality studies, climate modeling, policy monitoring and hazard warnings. The heritage for GOME-2 is in the ERS/GOME and Envisat/SCIAMACHY instruments. The current Level 2 (L2 data cover a wide range of products such as trace gas columns (NO2, BrO, H2CO, H2O, SO2, tropospheric columns of NO2, total ozone columns and vertical ozone profiles in high and low spatial resolution, absorbing aerosol indices from the main science channels as well as from the polarization channels (AAI, AAI-PMD, Lambertian-equivalent reflectivity database, clear-sky and cloud-corrected UV indices and surface UV fields with different weightings and photolysis rates. The Ozone Monitoring and Atmospheric Composition Satellite Application Facility (O3M SAF processing and data dissemination is operational and running 24/7. Data quality is quarantined by the detailed review processes for the algorithms, validation of the products as well as by a continuous quality monitoring of the products and processing. This is an overview paper providing the O3M SAF project background, current status and future plans to utilization of the GOME-2 data. An important focus is the provision of summaries of the GOME-2 products including product principles and validation examples together with the product sample images. Furthermore, this paper collects the references to the detailed product algorithm and validation papers.

  14. Luminescence properties of Na3YSi3O9:M3+ (M = Sm, Tb, Tm) glass ceramics

    Highlights: •Sm3+, Tb3+, or Tm3+ doped-Na3YSi3O9 GC emit reddish, green, or blue light, respectively. •Emission intensities of these glass ceramics are superior to corresponding phosphors. •Color tones of Na3YSi3O9:Sm3+, Tb3+, Tm3+ GC can be changed from warm white to cool white. •These glass ceramics have potential application in white LED devices. -- Abstract: The transparent Na3YSi3O9:M3+ (M = Sm, Tb, Tm) glass ceramics were prepared by high temperature melting with a heat-treatment at 750 °C. X-ray diffraction, transmission electron microscopy, and photoluminescence spectroscopy were used to investigate their structure and optical properties. The M3+ ions were introduced as luminescence centers into the Na3YSi3O9 glass ceramics. Under ultraviolet (UV) excitation, the Na3YSi3O9:Sm3+, Na3YSi3O9:Tb3+, and Na3YSi3O9:Tm3+ glass ceramics exhibited the characteristic transitions of Sm3+ (4G5/2 → 6HJ, J = 5/2 and 7/2), Tb3+ (5D4 → 7FJ, J = 6, 5 and 4), and Tm3+ (1D2 → 3F4), respectively. The color tones of Na3YSi3O9:Sm3+, Tb3+, Tm3+ glass ceramic changed from cool white (0.2589, 0.3119) to warm white (0.3231, 0.4491) by adjusting the excitation wavelength. The results indicated that the Na3YSi3O9:M3+ (M = Sm, Tb, Tm) glass ceramic is a potential matrix material for white light-emitting diodes (LEDs) under UV-LED excitation

  15. Overview of the O3M SAF GOME-2 operational atmospheric composition and UV radiation data products and data availability

    Hassinen, S.; Balis, D.; Bauer, H.; Begoin, M.; Delcloo, A.; Eleftheratos, K.; Gimeno Garcia, S.; Granville, J.; Grossi, M.; Hao, N.; Hedelt, P.; Hendrick, F.; Hess, M.; Heue, K.-P.; Hovila, J.; Jønch-Sørensen, H.; Kalakoski, N.; Kauppi, A.; Kiemle, S.; Kins, L.; Koukouli, M. E.; Kujanpää, J.; Lambert, J.-C.; Lang, R.; Lerot, C.; Loyola, D.; Pedergnana, M.; Pinardi, G.; Romahn, F.; van Roozendael, M.; Lutz, R.; De Smedt, I.; Stammes, P.; Steinbrecht, W.; Tamminen, J.; Theys, N.; Tilstra, L. G.; Tuinder, O. N. E.; Valks, P.; Zerefos, C.; Zimmer, W.; Zyrichidou, I.

    2016-02-01

    The three Global Ozone Monitoring Experiment-2 instruments will provide unique and long data sets for atmospheric research and applications. The complete time period will be 2007-2022, including the period of ozone depletion as well as the beginning of ozone layer recovery. Besides ozone chemistry, the GOME-2 (Global Ozone Monitoring Experiment-2) products are important e.g. for air quality studies, climate modelling, policy monitoring and hazard warnings. The heritage for GOME-2 is in the ERS/GOME and Envisat/SCIAMACHY instruments. The current Level 2 (L2) data cover a wide range of products such as ozone and minor trace gas columns (NO2, BrO, HCHO, H2O, SO2), vertical ozone profiles in high and low spatial resolution, absorbing aerosol indices, surface Lambertian-equivalent reflectivity database, clear-sky and cloud-corrected UV indices and surface UV fields with different weightings and photolysis rates. The Satellite Application Facility on Ozone and Atmospheric Chemistry Monitoring (O3M SAF) processes and disseminates data 24/7. Data quality is guaranteed by the detailed review processes for the algorithms, validation of the products as well as by a continuous quality monitoring of the products and processing. This paper provides an overview of the O3M SAF project background, current status and future plans for the utilisation of the GOME-2 data. An important focus is the provision of summaries of the GOME-2 products including product principles and validation examples together with sample images. Furthermore, this paper collects references to the detailed product algorithm and validation papers.

  16. On GAMER, plataforma de continguts sobre videojocs

    Villegas Bonachera, José Ricardo

    2015-01-01

    Desenvolupament d'una plana web amb disseny responsiu sobre videojocs en català a partir del gestor de continguts WordPress. Desarrollo de una página web con diseño responsivo sobre videojuegos en catalán a partir del gestor de contenidos WordPress. Bachelor thesis for the Multimedia program on Computer Science.

  17. Recursos y enlaces sobre comunidades de aprendizaje

    Ferrer Esteban, Gerard

    2005-01-01

    Obras y artículos sobre el proyecto Comunidades de Aprendizaje desarrollado en el Estado español. Tesis doctorales sobre comunidades de aprendizaje. Fundamentación teórica de las comunidades de aprendizaje. Sitios en Internet relacionados con las comunidades de aprendizaje y proyectos afines de desarrollo comunitario en contextos escolares.

  18. Historicismo: notas sobre um paradigma

    José D’Assunção Barros

    2012-08-01

    Full Text Available Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX. O primeiro ponto tratado é relativo às origens do paradigma Historicista na transição do século XVIII para o século XIX. Na sequência, aproximamo-nos da apropriação conservadora do paradigma historicista no novo contexto no qual a burguesia européia está assentada no Poder, combinando-se com a consolidação dos modernos estados-nações. A especificação das características deste paradigma constituem o principal ponto de análise

  19. Steady state hemodynamic and energetic characterization of the Penn State/3M Health Care Total Artificial Heart.

    Weiss, W J; Rosenberg, G; Snyder, A J; Pierce, W S; Pae, W E; Kuroda, H; Rawhouser, M A; Felder, G; Reibson, J D; Cleary, T J; Ford, S K; Marlotte, J A; Nazarian, R A; Hicks, D L

    1999-01-01

    Total Artificial Heart (TAH) development at Penn State University and 3M Health Care has progressed from design improvements and manufacturing documentation to in vitro and in vivo testing to characterize the system's hemodynamic response and energetic performance. The TAH system is completely implantable and intended for use as an alternative to transplantation. It includes a dual pusher plate pump and rollerscrew actuator, welded electronics and battery assembly, transcutaneous energy transmission system, telemetry, and a compliance chamber. In vitro testing was conducted on a Penn State mock circulatory loop with glycerol/water solution at body temperature. Tests were performed to characterize the preload and afterload response, left atrial pressure control, and power consumption. A sensitive preload response was demonstrated with left atrial pressure safely maintained at less than 15 mm Hg for flow rates up to 7.5 L/min. Variations in aortic pressure and pulmonary vascular resistance were found to have minimal effects on the preload sensitivity and left atrial pressure control. In vivo testing of the completely implanted system in its final configuration was carried out in two acute studies using implanted temperature sensors mounted on the electronics, motor, and energy transmission coil in contact with adjacent tissue. The mean temperature at the device-tissue interface was less than 4 degrees C above core temperature. PMID:10360721

  20. Encapsulating MAl 2O 4:Eu 2+, Dy 3+ (M = Sr, Ca, Ba) phosphors with triethanolamine to enhance water resistance

    Ji, Ping Ting; Chen, Xiang Ying; Wu, Ye Qin

    2011-12-01

    Traditional aluminates phosphors with persistent luminescence are chemically unstable to water or moisture. Thus, how to improve the water-resistance of these phosphors is becoming a key issue in their practical applications. In this work, a series of alkaline earth aluminate phosphors including MAl 2O 4:Eu 2+, Dy 3+ (M = Sr, Ca, Ba) have been prepared by a co-precipitation synthesis and postannealing approach, using 8-hydroxyquinoline and sodium oxalate as precipitants. The samples before and after encapsulation were well characterized by means of XRPD, FESEM, FT-IR, TGA-DTG and PL techniques as well as water resistance measurements. The precipitants involved can react with Al 3+ and Sr 2+ (or Ca 2+, Ba 2+) to form complex compounds in aqueous solution, which further convert into porous phosphors by postannealing method under reducing atmosphere. Next, triethanolamine encapsulation at room temperature was conducted onto their surfaces to improve the water resistance. The results reveal that the encapsulation of aluminate phosphors with triethanolamine can effectively enhance the water resistance, and minimally affect on persistent phosphorescence.

  1. U-3M plasma start-up scenario sustained by gas puffing as a different plasma confinement scenario: first results

    In order to reduce flux of neutrals into the plasma confinement volume, discharge start-up scenario maintained by impulse gas puffing (GP) has been proposed. Absence of constant working gas feeding in this scenario opens a possibility to reduce working gas pressure in the U-3M vacuum vessel. It was shown that the time of entire vessel filling after sharp gas puffing pulse is about 10-20 ms. In discharges with 5-6 kV on the RF generators and proposed start-up scenario, a delay between GP pulse and plasma creation was shorter than the chamber filling time.The same level of the electron density has been achieved in the discharge under consideration and conventional 5-6 kV discharge maintained by the constant gas feeding only. The Halpha emission waveform in the considered discharges is similar to its waveforms in the conventional devices where the sizes of vacuum chamber and plasma are close each other.

  2. SOLITONS: Dark spatial optical solitons in planar gradient waveguides in the Z-cut of the 3m symmetry crystals

    Frolova, M. N.; Borodin, M. V.; Shandarov, S. M.; Shandarov, V. M.; Larionov, Yu M.

    2003-11-01

    The propagation of light beams is studied in a planar photorefractive waveguide fabricated by high-temperature diffusion of metal ions in the Z-cut substrate of the 3m symmetry crystal. The wave equations are obtained for single-mode light beams with TE and TM polarisations in planar diffusion waveguides, which take into account the two-dimensional distribution of the optical field. Expressions are found for a nonlinear change in the refractive index when the photovoltaic mechanism makes a dominant contribution to the photorefractive effect. The propagation of single-mode light beams is analysed numerically for a Ti:Fe:LiNbO3 waveguide fabricated by the successive diffusion of titanium and iron into lithium niobate. It is shown that single-mode light beams with a smooth amplitude envelope can propagate without significant changes in the region of a dip in the intensity modelling a dark soliton. The relations between the amplitude and width of a dark spatial soliton are obtained for the TM modes of a photorefractive planar waveguide.

  3. The Horizontal Branch in the UV Colour Magnitude Diagrams. II. The case of M3, M13 and M79

    Dalessandro, Emanuele; Ferraro, Francesco R; Mucciarelli, Alessio; Cassisi, Santi

    2012-01-01

    We present a detailed comparison between far-UV/optical colour Magnitude Diagrams obtained with high-resolution Hubble Space Telescope data and suitable theoretical models for three Galactic Globular Clusters: M3, M13 and M79. These systems represents a classical example of clusters in the intermediate metallicity regime that, even sharing similar metal content and age, show remarkably different Horizontal Branch morphologies. As a consequence, the observed differences in the colour distributions of Horizontal Branch stars cannot be interpreted in terms of either first (metallicity) or a second parameter such as age. We investigate here the possible role of variations of initial Helium abundance (Y). Thanks to the use of a proper setup of far-UV filters, we are able to put strong constraints on the maximum Y (Y_{max}) values compatible with the data. We find differences Delta Y_{max} ~ 0.02-0.04 between the clusters with M13 showing the largest value (Y_{max} ~ 0.30) and M3 the smallest (Y_{max} ~ 0.27). In g...

  4. Patterns of mouse reticulon 3 mRNA and protein expression in the mouse central nervous system

    LIU Jin; QIANG Boqin; YUAN Jiangang; HUANG Xiaowei; PENG Xiaozhong; YANG Hongbo; YIN Bin; TAN Xinyu; FAN Ming; FAN Wenhong; LIU Bingyan

    2003-01-01

    Reticulons (RTN) are endoplasmic reticulumassociated protein complexes, which are localized in the endoplasmic reticulum (ER) and identified as markers for neuroendocrine differentiation. At least four different RTN genes have been identified in mammals, but in most cases,the functions of the encoded proteins except mammalian RTN4-A and RTN4-B are still elusive. In the present study,mouse reticulon 3 (mRTN3) is cloned and its expression pattern in a variety of tissues is investigated. Three alternatively spliced transcripts of 1.8, 2.8 and 4.2 kb are revealed by Northern blotting hybridization. The 1.8 and 2.8 kb transcripts are expressed in many tissues. The 2.8 kb transcript has a high level in brain and the 4.2 kb transcript is only found in brain. In situ hybridization and immunohistochemical analysis indicated its high expression in non-glial cells in some particular region of mouse central nervous system, such as hippocampus, sub-thalamus nucleus, thalamus nucleus and cerebrum cortex.

  5. NOAA ESRI Grid- 3m Bathymetric Slope of St. Croix (Buck Island), US Virgin Islands, Project NF-06-03, 2006, UTM 20 NAD83

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains an ESRI Grid representing the slope (in degrees) of the bathymetry of the north shore of St. Croix, US Virgin Islands, based on a 3 m...

  6. FoxP3 mRNA splice forms in synovial CD4+ T cells in rheumatoid arthritis and psoriatic arthritis

    Ryder, L. Rebekka; Bartels, Else Marie; Woetmann, Anders; Madsen, Hans Ole; Ødum, Niels; Bliddal, Henning; Danneskiold-Samsøe, Bente; Ribel-Madsen, Søren; Ryder, Lars P.

    2012-01-01

    Our aim was to elucidate the relative amount of the different splice forms of FoxP3 mRNA in CD4+ T cells in peripheral blood (PB) compared to synovial fluid (SF) in RA and PsA patients. FoxP3 mRNA was measured using a quantitative real-time PCR method. CD4+ T cells were isolated from 17 paired sa...

  7. Ensaio sobre Saramago = Essay on Saramago

    Weigert, Sergio

    2013-01-01

    Partindo da obra de José Saramago, Ensaio sobre a Cegueira, constrói-se o “Ensaio sobre Saramago” sob perspectiva filosófica, fundamentada particularmente em Fredric Jameson. A interrupção da quotidianidade, matéria do desenvolvimento do conteúdo, faz aflorar a hipótese da temporalidade congelada, suporte da argumentação do teórico. Levanta-se a discussão sobre Modernidade e Pós-Modernidade da obra de Saramago, avançando no recurso da ironia, não como alicerce, mas como teia que tece, envolve...

  8. Somos un envase : Discursos sobre el aborto

    Löcher, Jennifer Irene

    2014-01-01

    No hay persona que no tenga opinión acerca del asunto y, cada vez más, la sociedad argentina debate sobre la pregunta de si se debe legalizar/despenalizar el aborto o no. Nunca antes se habló tanto sobre el tema públicamente: se publican artículos en los diarios, hay manifestaciones a favor y hay manifestaciones en contra de la legalización del aborto. El siguiente trabajo pretende relevar y analizar discursos que circulan socialmente alrededor del debate sobre el aborto. (Párrafo extraíd...

  9. Concepciones sobre la docencia universitaria de calidad

    Arbeláez López, Ruby; Fortes del Valle, M. Carmen; Grau Rubio, Claudia

    2008-01-01

    Con esta investigación hemos querido participar en el proceso de búsqueda y construcción del sentido de calidad aplicado a la docencia universitaria, con el objetivo general de evidenciar las concepciones sobre docencia de calidad que pueden deducirse de los procesos de evaluación de los profesores universitarios. Nuestra meta final intenta propiciar la revisión de las políticas educativas y el enriquecimiento de la cultura sobre docencia y sobre evaluación docente. La mayor aportación de nue...

  10. Puente sobre el Oosterschelde, Holanda

    Hoving, H. T.

    1967-03-01

    Full Text Available This new bridge, forming part of the Delta project, is made of concrete, and was built by successive overhangs. Precast units were mainly used. The bridge is 5,000 m long, and is 11.85 m wide. The main spans are 95 m in length, except one, which can be opened up to sea traffic, which is 40 m long. The free height of the bridge over the sea is 15 m, which is insufficient for large ships. This required that one of the spans, in deep water, should open up, on hinges, and provide free passage to large ships. The intermediate bridge supports are of special interest. They rest on piles which go down to 38 m. They are hollow, cylindrical, of 4.35 m external diameter, and are driven into the ground in several stages, as they penetrate through the sands at the bottom of the Oosterschelde. To drive them in, an excavating device, inside the pile, was utilised, and also a dredging and suction mechanism, to clean out the bottom, and allow the piles to sink by gravity. But when external friction did not allow this to happen, the piles were weighed down with up to 500 tons of ballast. A series of three of these piles, in a row, makes up each bridge support. A cross member over the pile heads supports, in turn, the bridge deck. The bridge was built in successive sections, overhanging from each support, and then finally connected with a central portion. Use of precast units has been very extensive, so that the bridge can be justiaflably regarded as being prefabricated.Este nuevo puente, que forma parte del Plan de obras denominadas del Delta, es de hormigón y se ha construido por el procedimiento de voladizos sucesivos, utilizando, en su mayor parte, elementos prefabricados. Tiene una longitud total de 5.000 m; una anchura de 11,85 m; tramos principales de 95 m de luz, salvo uno, levadizo, que tiene 40 m. La altura libre sobre las ag^uas del mar es de 15 m, que es insuficiente para las naves de gran tonelaje; esto exigió que uno de sus tramos, en aguas

  11. Detailed DFT studies of the electronic structure and optical properties of KBaMSe{sub 3} (M = As, Sb)

    Azam, Sikander; Khan, Saleem Ayaz; Khan, Wilayat [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Muhammad, Saleh; Udin, Haleem [Materials Modeling Lab, Department of Physics, Hazara University, Mansehra (Pakistan); Murtaza, G., E-mail: murtaza@icp.edu.pk [Materials Modeling Laboratory, Department of Physics, Islamia College University, Peshawar (Pakistan); Khenata, R., E-mail: khenata_rabah@yahoo.fr [Laboratoire de Physique Quantique et de Modélisation Mathématique (LPQ3M), Département de Technologie, Université de Mascara, Mascara 29000 (Algeria); Shah, Fahad Ali [Materials Modeling Lab, Department of Physics, Hazara University, Mansehra (Pakistan); Minar, Jan [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Ahmed, W.K. [ERU, College of Engineering, United Arab Emirates University, Al Ain (United Arab Emirates)

    2015-09-25

    Highlights: • The compounds are studied by FP-LAPW method within LDA, GGA, EV-GGA approximations. • All the compounds show indirect band gap nature. • Bonding nature is mixed covalent and ionic. • High absorption peaks and reflectivity ensures there utility in optoelectronic devices. - Abstract: Bonding nature as well as the electronic band structure, electronic charge density and optical properties of KBaMSe{sub 3} (M = As, Sb) compounds have been calculated using a full-potential augmented plane wave (FP-LAPW) method within the density functional theory. The exchange–correlation potential was handled with LDA and PBE-GGA approximations. Moreover, the Engel–Vosko generalized gradient approximation (EV-GGA) and the modified Beck–Johnson potential (mBJ) were also applied to improve the electronic band structure calculations. The study of band structure shows that KBaAsSe{sub 3}/KBaSbSe{sub 3} compounds have an indirect band gap of 2.08/2.10 eV which are in close agreement with the experimental data. The bonding nature has been studied as well using the electronic charge density (ECD) contour in the (1 0 1) crystallographic plane. It has been revealed that As/Sb–O atoms forms a strong covalent, while Ba–Se atoms form weak covalent bonding and the ionic bonding is mainly found between K and Ba atoms. Moreover, the complex dielectric function, absorption coefficient, refractive index, energy-loss spectrum and reflectivity have been estimated. From the reflectivity spectra, we found that KBaAsSe{sub 3} compound shows greater reflectivity than KBaSbSe{sub 3}, which means that KBaAsSe{sub 3} compound can be used as shielding material in visible and also in ultra violet region.

  12. Design report for an indirectly cooled 3-m diameter superconducting solenoid for the Fermilab Collider Detector Facility

    The Fermilab Collider Detector Facility (CDF) is a large detector system designed to study anti pp collisions at very high center of mass energies. The central detector for the CDF shown employs a large axial magnetic field volume instrumented with a central tracking chamber composed of multiple layers of cylindrical drift chambers and a pair of intermediate tracking chambers. The purpose of this system is to determine the trajectories, sign of electric charge, and momenta of charged particles produced with polar angles between 10 and 170 degrees. The magnetic field volume required for tracking is approximately 3.5 m long an 3 m in diameter. To provide the desired δp/sub T/p/sub T/ less than or equal to 1.5% at 50 GeV/c using drift chambers with approx. 200μ resolution the field inside this volume should be 1.5 T. The field should be as uniform as is practical to simplify both track finding and the reconstruction of particle trajectories with the drift chambers. Such a field can be produced by a cylindrical current sheet solenoid with a uniform current density of 1.2 x 106 A/m (1200 A/mm) surrounded by an iron return yoke. For practical coils and return yokes, both central electromagnetic and central hadronic calorimetry must be located outside the coil of the magnet. This geometry requires that the coil and the cryostat be thin both in physical thickness and in radiation and absorption lengths. This dual requirement of high linear current density and minimal coil thickness can only be satisfied using superconducting technology. In this report we describe the design for an indirectly cooled superconducting solenoid to meet the requirements of the Fermilab CDF. The components of the magnet system are discussed in the following chapters, with a summary of parameters listed in Appendix A

  13. Characterization and thermal behavior of PrMO3 (M = Co or Ni) ceramic materials obtained from gelatin

    Graphical abstract: The micrograph in figure shows sample calcined at temperature 900 °C. The sample exhibits morphology with considerable porosity and the formation of agglomerated nanometric particles. Gelatin provides the system with a large amount of organic matter, which is then removed during calcinations, favoring the appearance of pores in the material. Highlights: ► Oxides with PrNiO3 and PrCoO3 were prepared by new method synthesis. ► The gelatin, through its carboxylate groups and amine, is an efficient director. ► The obtained materials have magnetic properties and application in catalysis. ► The decomposition kinetic study of bonding groups of gelatin with metallic ions that takes part in the synthesis of PrMO3. -- Abstract: Metal oxides with perovskite-type structure have attracted considerable interest in recent years due to their magnetic and electrical properties, as well as their catalytic activity. In this study, oxides with PrNiO3 and PrCoO3 composition were prepared by using gelatin powder as a precursor agent for its use as a catalyst. The powders obtained were calcined at 700 °C and 900 °C and characterized using the X-ray diffraction, thermal analysis (thermogravimetry and differential thermal analysis), infrared spectroscopy, temperature programed reduction and scanning electron microscopy techniques. Thermogravimetric data using the non-isothermal kinetic models of Flynn and Wall and “Model-free Kinetics” were used to determine the activation energy to study the decomposition kinetics of the ligand groups with system's metallic ions that takes part in the synthesis of PrMO3 (M = Ni or Co).

  14. Site-preferential design of itinerant ferromagnetic borides: experimental and theoretical investigation of MRh6B3 (M = Fe, Co).

    Misse, Patrick R N; Gillessen, Michael; Fokwa, Boniface P T

    2011-10-17

    Single-phase polycrystalline samples of the compounds MRh(6)B(3) (M = Fe, Co) as well as single crystals of CoRh(6)B(3) have been synthesized by arc-melting the elements under a purified argon atmosphere in a water-cooled copper crucible. The characterization of the new phases was achieved by using single-crystal and powder X-ray diffraction as well as EDX measurements. The two phases are isotypic and crystallize in the hexagonal Th(7)Fe(3) structure type (space group P6(3)mc, no. 186, Z = 2). In this structure, the magnetically active atoms (Fe, Co) are preferentially found on only one of the three available rhodium sites, and together with rhodium they build a three-dimensional network of interconnected (Rh/M)(3) triangles. Magnetic properties investigations show that both phases order ferromagnetically below Curie temperatures of 240 K (for FeRh(6)B(3)) and 150 K (for CoRh(6)B(3)). First-principles DFT calculations correctly reproduce not only the lattice parameters but also the ground state magnetic ordering in the two phases. These calculations also show that the long-range magnetic ordering in both phases occurs via indirect ferromagnetic coupling between the iron atoms mediated by rhodium. This magnetic structural model also predicts the saturation magnetizations to be 4.02 μ(B) for FeRh(6)B(3) (3.60 μ(B) found experimentally) and 2.75 μ(B) for CoRh(6)B(3). Furthermore, both phases are predicted to be metallic conductors as expected for these intermetallic borides. PMID:21905755

  15. Deuterium kinetic isotope effect for oxidation of perdeuterated sodium butyrate with manganate in 3 M sodium hydrochloride solution

    Deuterium kinetic effect, D-KIE, for oxidation of perdeuterided sodium butyrate, CD3(CD2)2COONa, with manganate in the aqueous solution of 3M NaOH has been determined in the temperature range 323-373 K. The temperature dependent kH/kD ratios are in the range from 17.59 at 323 K to 11,25 at 373 K. The activation energy difference, δQ0 = Q0DD - Q0=HH δH0DD - δH0HH = 9.20 kJ mol-1, and the Arrhenius preexponential factors ratio A0DD/A0HH is equal to 1.76, corresponding to δS0DD - δS0HH = 4.70 k J-1 as deduced from the Arrhenius and Eyring diagrams. This is the main evidence of tunnelling in the transfer of methylene hydrogens of butyrate to the negatively charged oxygens of manganate in very basic solutions. The k0HH/k0DD ratios, corrected for the ionic strength, have been reproduced by multiplying the (k0HH/k0DD)KIE value, caused by zero point energy differences, by the Bell tunnel correction QtHH.QtDD. The half width of the energy barrier, as approximated by an inverted parabola, was found to be equal to 5x10-11 m. The physico-chemical origin of the energy barrier for the oxidation of n-chain aliphatic carboxylates with MnO42- ions in strongly alkaline solutions has been discussed. The mechanisms of the permanganate versus manganate oxidation i. e., in acidic versus alkaline media are compared. (author)

  16. Detailed DFT studies of the electronic structure and optical properties of KBaMSe3 (M = As, Sb)

    Highlights: • The compounds are studied by FP-LAPW method within LDA, GGA, EV-GGA approximations. • All the compounds show indirect band gap nature. • Bonding nature is mixed covalent and ionic. • High absorption peaks and reflectivity ensures there utility in optoelectronic devices. - Abstract: Bonding nature as well as the electronic band structure, electronic charge density and optical properties of KBaMSe3 (M = As, Sb) compounds have been calculated using a full-potential augmented plane wave (FP-LAPW) method within the density functional theory. The exchange–correlation potential was handled with LDA and PBE-GGA approximations. Moreover, the Engel–Vosko generalized gradient approximation (EV-GGA) and the modified Beck–Johnson potential (mBJ) were also applied to improve the electronic band structure calculations. The study of band structure shows that KBaAsSe3/KBaSbSe3 compounds have an indirect band gap of 2.08/2.10 eV which are in close agreement with the experimental data. The bonding nature has been studied as well using the electronic charge density (ECD) contour in the (1 0 1) crystallographic plane. It has been revealed that As/Sb–O atoms forms a strong covalent, while Ba–Se atoms form weak covalent bonding and the ionic bonding is mainly found between K and Ba atoms. Moreover, the complex dielectric function, absorption coefficient, refractive index, energy-loss spectrum and reflectivity have been estimated. From the reflectivity spectra, we found that KBaAsSe3 compound shows greater reflectivity than KBaSbSe3, which means that KBaAsSe3 compound can be used as shielding material in visible and also in ultra violet region

  17. An experimental study of temperatures in cloud from release of flashing liquid CO2 in 3m long channel

    Amrit Adhikari, André V. Gaathaug, Dag Bjerketvedt, Knut Vaagsaether

    2014-01-01

    Full Text Available Flashing of the liquid CO2 is an accidental hazards that may occurs in many industrial sector such as, process industries, carbon capture and storage projects, crude oil extraction process etc. Sometimes the accidental release of liquid CO2 that causes the health hazards which may costs loss of lives and properties. In order to alleviate the aforementioned probable hazards, the experiment will be highly beneficial. This research activity is conducted through the temperature measurement in the cloud of flashing liquid CO2 confirming the formation of dry ice and measuring frontal velocity of the cloud as well as its height formed from the vapour CO2 dispersion. The liquid CO2 was released in the 3m long channel from the cylinder through two nozzles of diameter 0.5mm and 1.0mm. This leads the formation of dry ice measuring -73oC and -71oC from the nozzle sized 0.5mm and 1.0mm respectively. 0.5mm nozzle and 1.0mm nozzle having mass flow rate of liquid CO2 as 0.0089 kg/s and 0.029 kg/s, overall frontal velocity of 0.52 m/s and 1.51 m/s thus formed cloud height measuring 0.05m and 0.1m respectively. Frontal velocity of the cloud was found to be highest at distance of 0.5m from nozzle with 1.49 m/s and 5.5 m/s for both nozzles 0.5mm and 1.0mm diameter respectively. Upon the increasing distance from the nozzle, the temperature of the formed cloud was seen to be in increasing order.

  18. Activity identification of chimeric anti-caspase-3 mRNA hammerhead ribozyme in vitro and in vivo

    XU; Renhuan; (

    2001-01-01

    [1]Andrew, F., Gerard, E., A license to kill, Cell, 1996, 85: 781-784.[2]Thornberry, N. A., Lazebnik, Y., Caspases: Enemies within, Science, 1998, 281: 1312-1316.[3]Kijima, H., Ishida, H., Ohkawa, T. et al., Therapeutic application of ribozymes, Pharmacol. Ther., 1995, 68: 247-264.[4]Phylactou, L. A., Kilpatrick, M. W., Wood, M. J., Ribozymes as therapeutic tools for genetic disease, Hum. Mol. Genet., 1998, 7(10): 1649-1653.[5]Bettrand, E., Pictet, R ., Grange, T., Can heamerhead ribozymes be efficient tools inactivate gene function? Nucleic Acids Res., 1994, 22: 293-300.[6]Lieber, A., Strauss, M., Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library, Mol. Cell Biol., 1995, 15: 540-551.[7]Xu, R. H., Zhou, X. Q., Xie, Q. et al., Preparation and identification of hammerhead ribozyme in vitro against rat caspase-3 mRNA fragment, Chin. J. Hepatol., 2000,8: 361-363.[8]Liu, J., Jin, Y. X., Wang, D. B., A novel vector for abundant expression of antisense RNA, triplex-forming RNA and ribozyme in vivo, High Technology Letters, 2000, 6: 84-88.[9]Sambrook, J., Fritsch, E. F., Maniatis, T., Molecular Cloning: A Laboratory Manual, 2nd ed., New York: Cold Spring Harbor Laboratory Press, 1989.[10]Porter, A. G., J?nicke, R. U., Emerging roles of caspase-3 in apoptosis, Cell Death Differ, 1999, 6: 99-104.[11]Cryns, V., Yuan, J., Proteases to die for, Genes Dev., 1998, 12: 1551-1570.[12]Narendra, K. V., Anikumar, R. K., Fritz, E., Recent developments in the hammerhead ribozyme field, Nucleic Acids Research, 1998, 26: 5237-5242.

  19. CAST3M/ARCTURUS: A coupled heat transfer CFD code for thermal-hydraulic analyzes of gas cooled reactors

    The safety of gas cooled reactors (High Temperature Reactors (HTR), Very High Temperature Reactors (VHTR) or Gas Cooled Fast Reactors (GFR)) must be ensured by systems (active or passive) which maintain loads on component (fuel) and structures (vessel, containment) within acceptable limits under accidental conditions. To achieve this objective, thermal-hydraulics computer codes are necessary tools to design, enhance the performance and ensure a high safety level of the different reactors. Some key safety questions are related to the evaluation of decay heat removal and containment pressure and thermal loads. This requires accurate simulations of conduction, convection, thermal radiation transfers and energy storage. Coupling with neutronics is also an important modeling aspect for the determination of representative parameters such as neutronics coefficient (Doppler coefficient, Moderator coefficient, ...), critical position of control rods, reactivity insertion aspects, .... For GFR, the high power density of the core and its necessary reduced dimension cannot rely only on passive systems for decay heat removal. Therefore, forced convection using active safety systems (gas blowers, heat exchangers, ...) are highly recommended. Nevertheless, in case of station black-out, the safety demonstration of the concept should be guaranteed by natural circulation heat removal. This could be performed by keeping a relatively high back-up pressure for pure helium convection and also by heavy gas injection. So, it is also necessary to model mixing of different gases, the on-set of natural convection and the pressure and thermal loads onto the proximate or guard containment. In this paper, we report on the developments of the CAST3M/ARCTURUS thermal-hydraulics (Lumped Parameter and CFD) code developed at CEA, including its coupling to the neutronics code CRONOS2 and the system code CATHARE. Elementary validation cases are detailed, as well as application of the code to benchmark

  20. Spacewatch Astrometry of Asteroids and Comets with the Bok 2.3-m and Mayall 4-m Telescopes.

    Scotti, James V.; McMillan, Robert S.; Larsen, Jeffrey A.

    2014-11-01

    We use the Bok 2.3-m and Mayall 4-m telescopes on Kitt Peak to improve knowledge of the orbits and magnitudes of high priority classes of Near Earth Objects (NEOs) and other small bodies in need of recovery that cannot be reached with the Spacewatch 0.9-m and 1.8-m telescopes. Targets include NEOs with potential close encounters with Earth (Virtual Impactors; VIs), future targets of radar, NEOs previously detected by NEOWISE with orbits or albedos suggesting potential for cometary activity, potential destinations for spacecraft, returning NEOs with hard-won albedos and diameters determined by NEOWISE, and faint Potentially Hazardous Asteroids (PHAs). Notable targets successfully recovered include the Earth Trojan 2010 TK7 and the faint almost-lost VI 2011 BY24 discovered by NEOWISE. Between 2010 June 6 and 2014 July 23 the MPC accepted 1316 lines of astrometry by us with these telescopes on 207 different NEOs including 84 PHAs. We made 343 observations of PHAs with V>=22. Our average arc extension on large PHAs (with Hprivate communication). Support of Spacewatch was/is from JPL subcontract 100319 (2010-2011), NASA/NEOO grants NNG06GJ42G, NNX11AB52G, NNX12AG11G, NNX13AP99G, NNX14AL13G, and NNX14AL14G, the Lunar and Planetary Laboratory, the Brinson Foundation of Chicago, IL, the estates of R. S. Vail and R. L. Waland, and other private donors. We are also indebted to the MPC for their web services and to NOAO/KPNO and Steward Observatory for telescope time.

  1. Synthesis of LaMO{sub 3} (M = Fe, Co, Ni) using nitrate or nitrite molten salts

    Yang Jun, E-mail: tyangj@jnu.edu.c [Department of Chemistry, Jinan University, Shipai, Guangzhou, Guangdong Province 510632 (China); Li Runsheng; Zhou Junyi; Li Xiaoci; Zhang Yuanming; Long Yulin [Department of Chemistry, Jinan University, Shipai, Guangzhou, Guangdong Province 510632 (China); Li Yongwang [State Key Laboratory of Coal Conversion, Institute of Coal Chemistry, Chinese Academy of Sciences, Taiyuan 030001 (China)

    2010-10-22

    Research highlights: {yields} The molten salt, synthesis temperature, the oxidising properties, the basicity and oxidation states of the melt play an important role in LaMO{sub 3} synthesis. {yields} The system needs a careful optimisation of these parameters to obtain pure orthorhombic LaFeO{sub 3}, hexagonal LaCoO{sub 3} and LaNiO{sub 3}. Purely hexagonal LaNiO{sub 3} nanocrystals were successfully synthesized. {yields} SEM analyses were taken to investigate how the different parameters affect the microstructure of the samples. {yields} The specific surface area and crystallite size of LaMO{sub 3} show much difference in different system. - Abstract: Perovskite compound LaMO{sub 3} (M = Fe, Co, Ni) nanocrystals were successfully synthesized in molten nitrates or nitrites from a mixture of lanthanum nitrate and an M-containing nitrate for 2 h. The effect of the various process parameters on the phase purity, crystallite size, specific surface area and morphology of the synthesized nanocrystals were systematically studied by XRD, scanning electron microscopy (SEM), simultaneous TG/DSC and BET measurements. The results showed that salt medium, annealing temperatures (mainly 450-850 {sup o}C), oxidising properties and basicity of the melt played an important role in the synthesis of LaMO{sub 3}. The addition of Na{sub 2}O{sub 2} facilitated the reaction between La{sub 2}O{sub 3} and NiO or Co{sub 3}O{sub 4}, leading to the formation of LaNiO{sub 3} and LaCoO{sub 3} at a much lower temperature of 450 {sup o}C. Pure hexagonal LaNiO{sub 3} nanocrystals were obtained in molten NaNO{sub 3}-KNO{sub 3} eutectic with Na{sub 2}O{sub 2} at 550-750 {sup o}C.

  2. Puente sobre el rio Medway

    Freeman, Fox, Ingenieros

    1963-02-01

    have been prestressed both longitudinally and transversally. Between the two circulation roadways an elastic barrier has been placed, supported on metal posts.El puente sobre el río Medway tiene la misión de salvar dicho río en el nuevo trazado de carretera necesario para aliviar el denso tráfico estival entre Dower y Londres. Está situado en las proximidades de la ciudad de Rochester. La estructura se ha construido utilizando las vías de concurso. De todos los tipos presentados se eligió una estructura de hormigón armado. La longitud total de la obra es de 1.000 m. Los tres tramos principales de la obra salvan el río. El central es de 152 m de luz, y los dos adyacentes son de 103 m cada uno. Los accesos tienen un total de 18 tramos, que arrojan una longitud de 654 m. La anchura del puente es de 34 m, y la calzada se ha subdividido en dos direcciones de tráfico de 7,30 m cada una y, además, se han dejado dos espaldones laterales de 2,40 m de anchura. En planta se puede admitir que el puente tiene una alineación recta con una ligerísima curva, y que en el plano vertical presenta una pendiente de desagüe entre las pilas 9 y 10. Los estribos son de hormigón armado: tipo celular el del este y de hormigón en masa el del oeste. Los estribos se apoyan sobre pilotes hexagonales de hormigón armado cuya circunferencia circunscrita tiene 55 cm de radio y de 12 a 20 m de longitud. Cuando el firme se hallaba a profundidades inferiores a 6 m, los estribos se cimentaban directamente sobre el firme. Las pilas constituyen pórtico y tienen una altura variable de 9 a 30 m sobre el nivel del suelo. Los tramos de acceso forman una estructura continua simplemente apoyada. Cada tramo se compone de ocho vigas longitudinales de 30 a 41 m de longitud y de 190 toneladas cada una. Estas vigas son del tipo pretensado y prefabricado. El tramo central es del tipo cantilever, constituido por dos brazos, de 30 m de longitud, formados por vigas cajón. Cada una de estas vigas consta

  3. PERSPECTIVAS INFANTILES SOBRE LA TERRITORIALIDAD

    Noelia Enriz

    2009-12-01

    Full Text Available En este trabajo nos proponemos un acercamiento a las diversas ideas infantiles sobre el territorio habitado, en el contexto particular de la población mbyá guaraní de Misiones. La fragilidad territorialidad a la que es expuesta la población indígena en Argentina se manifiestan cotidianamente en diversas áreas. La población mbyá, ha sido surcada por los límites de los estados nacionales de Paraguay, Brasil y Argentina. La sedentarización y los cercamientos de tierras en los diferentes estados, han impulsado transformaciones de las lógicas de subsistencia, de habitación y organización comunitaria. En el caso de la provincia de Misiones la acreditación burocrática de los títulos de tierras se encuentra aplazada, el estado no se compromete con la concreción de este derecho.

  4. Sobre a psicopatologia dos atos

    Roberto Calazans

    2015-07-01

    Full Text Available Este artigo pretende apresentar a psicopatologia dos atos a partir do esquema de Jacques Lacan sobre a angústia. Diferenciamos os acting-out, a passagem ao ato, os sintomas, as inibições e a angústia fazendo uma duplicação do esquema de Lacan levando em consideração os registros do simbólico, do real e do imaginário. Esse esquema permite uma abordagem da questão dos atos do sujeito sem cair em uma perplexidade do clínico, nem na confusão entre os atos e a ação. Permite também uma melhor orientação do clínico em relação às diversas modalidades de respostas subjetivas que não se restringem à questão sintomática, que é o campo inaugural da clínica psicanalítica desde a sua fundação por Sigmund Freud. Acreditamos contribuir, assim, para um maior esclarecimento desse esquema no ensino de Lacan e para que ele possa servir de orientação para o tratamento dos atos do sujeito na clínica.

  5. Estudo multicasos sobre atividades inovativas

    Sonia Regina Hierro Parolin

    2013-09-01

    Full Text Available Em estudos sobre competitividade argumenta-se que as empresas necessitam de estratégias baseadas em inovações e de capacidades internas em constantes e intensas transformações, não somente nos padrões tecnológicos, mas também no encadeamento do processo de gestão das atividades inovativas, como processos dinâmicos, não lineares e diversificados, em função de múltiplos fatores dos ambientes interno e externo. Para contribuir com essas discussões, neste artigo apresenta-se um estudo multicasos em quatro indústrias de médio e grande portes, de segmentos, densidades tecnológicas e históricos com inovações diferentes entre si. Como principais resultados, salientam-se o encadeamento das atividades inovativas como parte de uma estratégia organizacional para obter resultados com inovação e a afluência de todas as pessoas, e não somente as alocadas em pesquisa e desenvolvimento, para o cumprimento dessa estratégia.

  6. El Impuesto sobre Sociedades - Tema 5

    Andrés Aucejo, Eva

    2008-01-01

    El Impuesto sobre Sociedades: Hecho imponible. Sujeto pasivo. Imputación temporal de ingresos y gastos. Régimen de transparencia fiscal. La base imponible: Ingresos computables, partidas deducibles y no deducibles. Reinversión de beneficios extraordinarios.

  7. Los derechos de autor sobre obtenciones vegetales

    Rosario Silva Gilli

    2015-01-01

    Full Text Available Contenido: Las creaciones en la agricultura. Los derechos de autor sobre obtenciones vegetales. El Convenio Internacional para la protección de las obtenciones vegetales (París 1961 y sus revisiones de Ginebra 1972, 1978,1991 Objeto de la protección legal. Condiciones del cultivar. Alcance de la protección. La protección de obtenciones vegetales en el Mercosur. Los Derechos de autor en el Mercosur. El Protocolo de Armonización de normas sobre Propiedad Intelectual en el Mercosur. El Acuerdo de Cooperación y facilitación sobre la protección de las obtenciones vegetales en los Estados Partes del Mercosur.  Alcance de la normativa Mercosur. Los Derechos sobre cultivares en Uruguay. Los Derechos de autor como derechos humanos. ¿Derechos de autor vs. derecho de propiedad intelectual? Reflexión final

  8. CAST3M/ARCTURUS: a coupled heat transfer / CFD code for thermal-hydraulic analyses of gas cooled reactors

    , heat exchangers...) are highly recommended. Nevertheless, in case of a total loss of station service power, the safety demonstration of the concept should be guaranteed by natural circulation decay heat removal. This could be performed by keeping a relatively high back-up pressure for pure He natural convection and also by heavy gas injection. So, it also necessary to compute the mixing of different gases and the on-set of natural convection. In this paper, we will report on the developments of the CAST3M/ARCTURUS thermal-hydraulics code developed at CEA, including its coupling to the neutronics code CRONOS2 and the system code CATHARE. Elementary validation cases will be detailed, as well as application of the code to benchmark problems such as the GT-MHR or the HTTR. Examples of thermal-hydraulic calculations decay heat removal of fast reactors designs (GCFR) will also be described. (authors)

  9. Overview of the O3M-SAF validation facility for operational GOME-2 NO2 column data

    Pinardi, Gaia; Lambert, Jean-Christopher; Granville, Jos; van Roozendael, Michel; Delcloo, Andy; Debacker, Hugo; Valks, Pieter; Hao, Nan

    In the framework of EUMETSAT's Satellite Application Facility on Ozone and Atmospheric Chemistry Monitoring (O3M-SAF,) nitrogen dioxide (NO2) total column and tropospheric column data are generated operationally from GOME-2 measurements in near-real-time (within 2:30 hours after sensing). NO2 column data are retrieved from the Earth radiance and solar irradiance spectra by a chain of several modules (currently, the level-0-to-1 processor v4.0 and the level-1-to-2 DOAS retrieval processor GDP v4.3). These intermediate modules calculates the parameters needed to derive the final column data: the slant column density along the optical path, the fractional cover and top pressure of clouds affecting the measurement scene, the geometrical enhancement factor (AMF, needed to convert slant into vertical columns), and the NO2 stratospheric reference to be subtracted from the total column to obtain the tropospheric column. In order to validate the final product (the total and tropospheric NO2 columns) in the best way, and due to the complexity of the GOME-2 retrieval chain and the existing issues related to the set-up of a validation strategy in an operational environment, an end-to-end validation ap-proach has been developed, as recommended by Reference Protocols and Guidelines. To ensure meaningful and continuous quality assessment of GOME-2 NO2 data products, the end-to-end validation approach performs the verification and validation of critical individual components of the level-1-to-2 retrieval chain. Particular interest is given to recurring validation issues, such as the particular way remote sensing samples and smoothes the significant variability of atmospheric NO2, the diurnal cycle of NO2, the poor availability of correlative measure-ments (especially for tropospheric column), as well as the current lack of homogenisation of the validation methods. The end-to-end validation process of GOME-2 NO2 data is based on a set of correlative obser-vations performed by

  10. Hyperfine interactions studies in perovskite oxides of the type LaMO3 (M = Fe, Cr, Mn and Co)

    ABO3-type perovskite oxides have ideal cubic structure and usually show distortions to the orthorhombic or rombohedric symmetry. The A and B siteshave 12-fold and 6-fold oxygen coordination, respectively. Distortions of thecubic structure give rise to new electric, structural and magnetic propertieswhich have great technological and scientific interests. Magnetic dipole and electric quadrupole hyperfine interaction measurements were obtained using111In -> 111 Cd , 181 Hf -> 181 Ta e 140 La -> 140Ceradioactive nuclei substituting for the A or B sites via Perturbed Angulargamma-gamma Correlation technique(1-4). LaMO3 (M = Fe, Cr, Mn and Co)samples were prepared through the chemical route known as Sol-Gel techniqueand analyzed with x-ray diffraction. Both 111In and 181 Hf nuclei wereintroduced in to the sample during the chemical procedure and the 140 Lawas obtained by irradiating with neutrons in the IPEN reactor the natural Lapresent in the samples. One of the aims of this work was the analysis of theElectric Field Gradient (EFG) in the A and B sites as function oftemperature, crystal structure or the electronic characteristic of thetransition metal in the B site. The temperature range of the measurements wasabout from 4 K to 1400 K. The experimental EFG showed to be dependent of thesite occupation and the nuclear probe used in the measurements. Spintransition phenomena were also observed in LaCoO3 samples, which confirmed amodel used to interpret the spin properties in such compound.Crystallographic phase transition effects on the hyperfine parameters inperovskites where M = Fe, Cr and K4n were also analyzed. An additional aim ofthis work was to carry out measurements in the antiferromagnetic region ofthe systems with M = Fe, Cr and Mn using the three radioactive nuclei. Theresults for the magnetic interaction measurements showed a strong influenceof the substitutional sites in the supertransferred magnetic hyperfine fieldfor all the three probe nuclei. The

  11. PERSPECTIVAS INFANTILES SOBRE LA TERRITORIALIDAD

    NOELIA ENRIZ

    2009-12-01

    Full Text Available In this paper we propose a different approach to children's ideas about the geographical area in the particular context of the Mbyá Guarani population, from Misiones (Argentine. The territorial fragility, that is exposed to the indigenous people in Argentina aremanifested daily in several areas. Mbyá population, has been crossed by the boundaries of national states of Paraguay, Brazil and Argentina. The sedentary and enclosures land processes in different states, have prompted changes in the logic of subsistence, housing and community organization. In Misiones province case, bureaucratic accreditation of land titles is postponed, the state is not committed to the realization of this right.RESUMEN: En este trabajo nos proponemos un acercamiento a las diversas ideas infantiles sobre el territorio habitado, en el contexto particular de la población mbyá guaraní de Misiones. La fragilidad territorialidad a la que es expuesta la población indígena en Argentina se manifiestan cotidianamente en diversas áreas. La población mbyá, ha sido surcada por los límites de los estados nacionales de Paraguay, Brasil y Argentina. La sedentarización y los cercamientos de tierras en los diferentes estados, han impulsado transformaciones de las lógicas de subsistencia, de habitación y organización comunitaria. En el caso de la provincia de Misiones la acreditación burocrática de los títulos de tierras se encuentra aplazada, el estado no se compromete con la concreción de este derecho.

  12. Consideraciones preliminares sobre la credibilidad

    Fernando Verdugo

    2004-01-01

    Full Text Available A modo de introducción al Seminario Interno de Profesores de la Facultad de Teología de la PUC, el autor recuerda, en primer lugar, lo que suele entenderse por "credibilidad" y, también, algunos de los criterios generales por los cuales algo o alguien adquiere la calidad de creíble (el que sea razonable, relevante o significativo, capaz de producir gozo estético, etc.. Luego, en la parte más extensa, el autor vuelve a llamar la atención sobre la necesidad de atender a los condicionamientos culturales de la fe cristiana. La fe, al igual que toda experiencia humana, está culturalmente mediada. Tomar conciencia de ese hecho y asumir las consecuencias metodológicas es indispensable para una teología que quiere poner atención a los desafíos actuales y contribuir así a la credibilidad del cristianismoThis article reprints the introductory session to the internal seminar of lecturers from the Faculty of Theology of the UC. In the first place, the author sums up what is usually understood by `credibility' and the general criteria through which something or someone gains credibility (being reasonable, relevant or significant, capable of producing aesthetic pleasure. Then the author deals at length with the need to take notice of the cultural conditionings of the Christian faith. The faith, the same as any other human experience, is culturally mediated. It is crucial for theology to become aware of this fact and come to terms with its methodological consequences, if it wants to face current challenges and so contribute to the credibility of Christianity

  13. Analysis of CD4+CD25+ Regulatory T Cells and Foxp3 mRNA in the Peripheral Blood of Patients with Asthma

    XUE Keying; ZHOU Yongming; XIONG Shengdao; XIONG Weining; TANG Tao

    2007-01-01

    The changes of CD4+CD25+ regulatory T cells (CD4+CD25+ Treg) and Foxp3 mRNA in peripheral blood mononuclear cells (PBMCs) from patients with asthma were investigated in order to elucidate the possible roles of CD4+CD25+ Treg in the development of asthma. The peripheral blood samples were collected from 29 healthy controls (normal control group) and 78 patients with asthma which included 30 patients in exacerbation group, 25 patients in persistent group, and 23 patients in remission group. By using flow cytometry and RT-PCR, the CD4+CD25+ Treg ratio and Foxp3 mRNA in PBMCs were detected. The CD4+CD25+ Treg ratio and Foxp3 mRNA in PBMCs of exacerbation and persistent groups were lower than that of remission and normal control groups (P<0.05). Although the CD4+CD25+ Treg ratio and Foxp3 mRNA of remission group were also lower than that of normal control group, there was no significant difference between them (P>0.05). As compared with persistent group, exacerbation group had lower CD4+CD25+ Treg ratio and Foxp3 mRNA (P<0.05). It was indicated that the decrease of CD4+CD25+Treg ratio and its function in PBMCs may be responsible for pathogenesis of asthma.

  14. Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3.

    Célia Dechavanne

    Full Text Available Mass spectrometry (MS analysis for detection of immunoglobulins (IG of the human IgG3 subclass is described that relies on polymorphic amino acids of the heavy gamma3 chains. IgG3 is the most polymorphic human IgG subclass with thirteen G3m allotypes located on the constant CH2 and CH3 domains of the gamma3 chain, the combination of which leads to six major G3m alleles. Amino acid changes resulting of extensive sequencing previously led to the definition of 19 IGHG3 alleles that have been correlated to the G3m alleles. As a proof of concept, MS proteotypic peptides were defined which encompass discriminatory amino acids for the identification of the G3m and IGHG3 alleles. Plasma samples originating from ten individuals either homozygous or heterozygous for different G3m alleles, and including one mother and her baby (drawn sequentially from birth to 9 months of age, were analyzed. Total IgG3 were purified using affinity chromatography and then digested by a combination of AspN and trypsin proteases, and peptides of interest were detected by mass spectrometry. The sensitivity of the method was assessed by mixing variable amounts of two plasma samples bearing distinct G3m allotypes. A label-free approach using the high-performance liquid chromatography (HPLC retention time of peptides and their MS mass analyzer peak intensity gave semi-quantitative information. Quantification was realized by selected reaction monitoring (SRM using synthetic peptides as internal standards. The possibility offered by this new methodology to detect and quantify neo-synthesized IgG in newborns will improve knowledge on the first acquisition of antibodies in infants and constitutes a promising diagnostic tool for vertically-transmitted diseases.

  15. Ligand exchange and complex formation kinetics studied by NMR exemplified on fac-[(CO)3M(H2O)]+ (M = Mn, Tc, Re)

    Helm, Lothar

    2008-01-01

    In this review ligand exchange and complex formation reactions on fac-[(CO)3M(H2O)3]+ (M = Mn, Tc, Re) and on fac-[(CO)2(NO)Re(H2O)3]2+ are presented. A variety of experimental NMR techniques are described and it is shown that sometimes combinations of techniques applied at variable temperature or variable pressure allowed to measure exchange rate constants and their activation parameters as well as thermodynamic parameters. Furthermore, the use of uncommon nuclei for NMR like 17O or 99Tc ext...

  16. DISERTACIÓN SOBRE JUSTICIA Y EQUIDAD

    Sayuri P. Tamura M.

    2001-01-01

    Full Text Available «Disertación sobre equidad y justicia» es básicamente una respuesta a una inquietud en particular que yo tenía sobre las distintas posiciones que existen sobre estos dos temas y cómo definir cuál es la más acertada. Hice una descripción del punto de vista de Amartya Sen –la violación de los derechos sobre la propiedad privada es justificable si evitan las hambrunas2– frente al de Robert Nozick –la propiedad privada es un derecho fundamental y como tal debe ser respetado3–, sin embargo, aunque ambos enfoques son totalmente contrarios tienen mucho sentido, por lo cual es bastante difícil decidirse por uno en particular. Fue de esta forma, enfrentando sus opiniones, que yo logré desarrollar una posición frente a estas dos perspectivas, y así dar mi opinión al DISERTACIÓN SOBRE JUSTICIA Y EQUIDAD SAYURI P. TAMURA M. Estudiante de Economía y Negocios Internacionales de la Universidad ICESI. respecto. Al final, llegué a una conclusión, que aunque no es la más original y tampoco es la única, tiene mucho sentido y seguramente de ser posible, la situación del país podría cambiar para bien.

  17. Impacto psicosocial del Downsizing sobre los trabajadores

    CRISTÓBAL JIMÉNEZ JIMÉNEZ

    2006-01-01

    Full Text Available El presente trabajo intenta ahondar en lo expuesto en un trabajo anterior sobre el downsizing como fenómeno psicosociolaboral, analizando su impacto psicosocial. En primer lugar, se exponen los diferentes niveles de comprensión de este fenómeno, para pasar al análisis de los efectos y consecuencias sobre las personas, diferenciando entre dos tipos de víctimas: a los que se van de la organización (despedidos y b los que se quedan en la organización (supervivientes, prestando especial atención a lo que se conoce ya como el "síndrome del superviviente", para lo que se aporta información sobre sus características, las variables moderadoras que intervienen y los modelos explicativos del mismo. Se termina con algunas consideraciones sobre la actualidad y relevancia de dicho síndrome sugiriendo la idea de que el fenómeno del downsizing y sus consecuencias sobre las personas nos enfrenta a lo que podríamos ya considerar como un nuevo síndrome de la Psicopatología Laboral: el síndrome del superviviente.

  18. Ensaio sobre Saramago = Essay on Saramago

    Weigert, Sergio

    2013-01-01

    Full Text Available Partindo da obra de José Saramago, Ensaio sobre a Cegueira, constrói-se o “Ensaio sobre Saramago” sob perspectiva filosófica, fundamentada particularmente em Fredric Jameson. A interrupção da quotidianidade, matéria do desenvolvimento do conteúdo, faz aflorar a hipótese da temporalidade congelada, suporte da argumentação do teórico. Levanta-se a discussão sobre Modernidade e Pós-Modernidade da obra de Saramago, avançando no recurso da ironia, não como alicerce, mas como teia que tece, envolvendo tecido e artista.

  19. First-principles investigation of electronic, mechanical and thermodynamic properties of L12 ordered Co3(M, W) (M = Al, Ge, Ga) phases

    Studies were carried out on the equilibrium structural, temperature-dependent mechanical and thermodynamic properties of the Co3(M, W) (M = Al, Ge, Ga) phases in terms of first-principles calculations. The results of the ground-state elastic constants revealed that Co3(M, W) phases are mechanically stable and possess intrinsic ductility. It was found that the elastic heat-resistant properties of Co3(Ge, W) phase are inferior to those of Co3(Al, W) and Co3(Ga, W). Analyzing the charge density difference provides the explanation that the sharp decrease in mechanical properties is mainly due to the weakening of Co–Ge bonding at elevated temperatures for Co3(Ge, W). The elastic anisotropy as a function of temperature is discussed using a universal index. It is observed that Co3(M, W) phases show a high degree of elastic anisotropy. The degree of elastic anisotropy could be significantly decreased by an increase in temperature for Co3(M, W). The lattice vibration is treated with the quasiharmonic phonon approach, considering both the vibrational and thermal electronic contributions. The thermodynamic properties as a function of temperature are computed without any adjustable parameters, including heat capacity, entropy, enthalpy and thermal expansion coefficient

  20. Developmentally Regulated Expression of HDNF/NT-3 mRNA in Rat Spinal Cord Motoneurons and Expression of BDNF mRNA in Embryonic Dorsal Root Ganglion.

    Ernfors, Patrik; Persson, Håkan

    1991-01-01

    Northern blot analysis was used to demonstrate high levels of hippocampus-derived neurotrophic factor/neurotrophin-3 (HDNF/NT-3) mRNA in the embryonic day (E) 13 - 14 and 15 - 16 spinal cord. The level decreased at E18 - 19 and remained the same until postnatal day (P) 1, after which it decreased further to a level below the detection limit in the adult. In situ hybridization revealed that the NT-3 mRNA detected in the developing spinal cord was derived from motoneurons and the decrease seen at E18 - 19 was caused by a reduction in the number of motoneurons expressing NT-3 mRNA. The distribution of NT-3 mRNA-expressing cells in the E15 spinal cord was very similar to the distribution of cells expressing choline acetyltransferase or nerve growth factor receptor (NGFR) mRNA. Moreover, a striking similarity between the developmentally regulated expression of NT-3 and NGFR mRNA was noted in spinal cord motoneurons. A subpopulation of all neurons in the dorsal root ganglia expressed brain-derived neurotrophic factor (BDNF) mRNA from E13, the earliest time examined, to adulthood. These results are consistent with a trophic role of NT-3 for proprioceptive sensory neurons innervating the ventral horn, and imply a local action of BDNF for developing sensory neurons within the dorsal root ganglia. PMID:12106253

  1. Influência do "primer" sobre o esmalte na resistência ao cisalhamento de sistemas adesivos

    RUSSO Eliza Maria Agueda; Garone NETTO Narciso; Rubens Corte Real de CARVALHO; Márcio Garcia dos SANTOS

    1998-01-01

    A proposta deste estudo foi comparar a adesão ao esmalte de dois sistemas adesivos de frasco único com sistemas que usam "primer" e "bond" separadamente, com o objetivo de verificar se a força de adesão da resina composta ao esmalte é influenciada pela presença do "primer" de dentina sobre o esmalte. Foram avaliados quatro sistemas adesivos: ONE STEP (Bisco), PRIME & BOND (Dentsply), SCOTCHBOND MULTI-PURPOSE PLUS (3M) e PROBOND (Dentsply). Molares humanos foram seccionados no sentido ocluso-c...

  2. Impacto psicosocial del Downsizing sobre los trabajadores

    CRISTÓBAL JIMÉNEZ JIMÉNEZ; JOSÉ LUIS SÁNCHEZ LAGUNA

    2006-01-01

    El presente trabajo intenta ahondar en lo expuesto en un trabajo anterior sobre el downsizing como fenómeno psicosociolaboral, analizando su impacto psicosocial. En primer lugar, se exponen los diferentes niveles de comprensión de este fenómeno, para pasar al análisis de los efectos y consecuencias sobre las personas, diferenciando entre dos tipos de víctimas: a) los que se van de la organización (despedidos) y b) los que se quedan en la organización (supervivientes), prestando especial atenc...

  3. Principios sobre semáforos

    VALENCIA ALAIX, VÍCTOR GABRIEL

    2000-01-01

    Debido a la ausencia de una publicación que reuniese los aspectos más relevantes sobre semáforos y en el marco académico sobre ingeniería de tránsito de los cursos de pregrado y posgrado en Vías y Transporte de la Universidad Nacional de Colombia - Sede Medellín, se ha preparado este documento como guía introductoria a dicho tema. En su preparación se han recogido los tópicos principales de varias publicaciones internacionales y nacionales, además, su desarrollo ha considerado la experi...

  4. Rastros: dizendo sobre os fazeres/dizeres

    MELLO MARISOL BARENCO CORRÊA DE

    2001-01-01

    Com vistas ao aclaramento de noções erroneamente herdadas do contexto social e histórico da cultura moderna ocidental, que teve/tem como um de seus projetos o "apagamento" do sujeito, ou o distanciamento entre os sujeitos e suas formas de fazer, dizer, pensar, este artigo pretende contribuir com elementos para a construção de um outro paradigma nas ciências humanas. Trata-se de um relato sobre o processo de construção de nossa própria pesquisa, articulado à reflexão sobre as diversas formas d...

  5. Sobre la esclavitud: libro de artista

    MACHADO JIMÉNEZ, ALBERTO

    2015-01-01

    Sobre la esclavitud es un libro de artista, donde encontraremos imágenes acompañadas de breves frases que hacen referencia al tema propuesto en cada ilustración para que así se pueda comprender mejor la intención de este trabajo, reflexionar sobre la manera que tenemos de ver las cosas, en este caso, con respecto a la esclavitud. Dar a conocer distintas formas de ser esclavo en este sistema sería uno de los objetivos principales. Hacer litografías, dibujos con el uso de acua...

  6. Consideraciones sobre diferentes procesos productivos y sus consecuencias sobre el medio ambiente

    Caridad Ramos Alvariño

    2004-01-01

    En el presente trabajo se exponen algunas consideraciones sobre diferentes procesos productivos y sus consecuencias sobre el medio ambiente. La disminución del impacto negativo de algunas producciones sobre el medio ambiente es favorable, pero el problema va más allá y de lo que se trata es de la necesidad de una transformación sostenible de las producciones que puedan conducir a una vida agradable y una naturaleza conservada entre otras muchas cuestiones que agobian hoy al mundo. La solución...

  7. Sobre o natural e o actor

    Tavares, Margarida

    2010-01-01

    Neste artigo, procura-se reflectir sobre o conceito de natural quando aplicado ao trabalho do actor. Parte-se de quatro relevantes textos da dramaturgia ocidental, a saber: Hamlet, de Shakespeare; Crítica da ‘Escola das mulheres’ e O improviso de Versalhes, de Molière; e O teatro cómico, de Goldoni.

  8. Las fuentes cristianas sobre Jesús

    Melero Martínez, J.M.

    2010-01-01

    Full Text Available El artículo es una presentación de las fuentes históricas sobre Jesús de Nazaret: fuentes sinópticas, fuente Q, fuentes afines a la gnosis, fragmentos de evangelio con material sinóptico o joánico, evangelios judeocristianos y otras fuentes.

  9. Sobre un sistema no lineal de epidemias

    Ortega S., Luis

    2012-01-01

    Un modelo sobre epidemias que describe la población infectada y la población susceptible de ser infectada en el cual se toma en consideraci6n el efecto de difusión es el siguiente: [Formula Matemática].

  10. Feasibility of CDP seismic reflection to image structures in a 200-m deep, 3-m thick coal zone near Palau, Coahuila, Mexico

    Miller, R.D.; Saenz, V.; Huggins, R.J. (Kansas University, Lawrence, KS (USA). Kansas Geological Survey)

    1992-10-01

    The common-depth-point (CDP) seismic-reflection method was used to delineate subsurface structure in a 3-m thick, 220-m deep coal zone in the Palau area of Coahuila, Mexico. An extensive series of walkaway-noise tests was performed to optimize recording parameters and equipment. Reflection events can be interpreted from depths of approximately 100 to 300 m on CDP stacked seismic sections. The seismic data allow accurate identification of the horizontal location of the structure responsible for a drill-discovered 3-m difference in coal-zone depth between boreholes 150m apart. The reflection method can discriminate folding with wavelengths in excess of 20 m and faulting with offset greater than 2 m at this site.

  11. Comparisons of fission track age-determination and radioactivation analysis among radiation fields. Characteristic values for pneumatic tube, JRR-3M PN2

    Suzuki, Tatsuro [Kagoshima Univ. (Japan). Faculty of Education; Tomura, Kenji

    1996-01-01

    It is necessary for Fission track age determination and radioactivation analysis to define the energy spectrum of a reactor neutron as the basis for calculating the nuclear reaction rate. This study was made aiming to define the spectrum for PN2 pneumatic tube of No. 3 plant of Japan Atomic Energy Research Institute (JAERI). Characteristics such as conventional flux, cross reaction, neutron temperature and integral fast flux were examined for 3 facilities; JRR-2, JRR-4 and JRR-3M. And the neutron spectrum for each facility was estimated based on the assumptions; Maxwell distribution for thermal neutrons, 1/E for intermediate neutrons and Watt`s formula for fast neutrons. The present results showed that the spectrum for JRR-3M, PN2 was discontinuous in the range from the intermediate to the fast neutron, whereas those for other facilities were found considerably improved. (M.N.)

  12. Behaviour of the radiation of the suprathermal electrons at the Uragan-3M torsatron after rf heating off from ECE measurements

    The microwave radiometry is a well-known diagnostics to obtain the information on temporal evolution and radial profile of the electron temperature at U-3M torsatron plasma experiments. However, under low plasma density with this diagnostics we report on the large production of runaway electrons after RF heating pulse off. We notice a gradually increasing of the radiometer signal at the frequencies that match the second and third harmonics of electron cyclotron emission of the extraordinary mode. This effect could be explained with the existence of the ''runaway'' electrons in U-3M discharge. A phenomenological description of this process is presented, where the time evolution of the ECE radiation signal is compared to the electron density evolution

  13. One step synthesis of lamellar R-3m LiCoO2 thin films by an electrochemical-hydrothermal method

    Highlights: · Theoretical calculation of the potential-pH diagram at temperatures between 150 and 200 deg. C. · LiCoO2 films deposited by an original electrochemical and hydrothermal process. · Synthesis of the lamellar R-3m LiCoO2 at temperature as low as 150 deg. C. · Relevant electrochemical performances of as-synthesized films in liquid electrolyte. - Abstract: In this study, we report the synthesis of lamellar R-3m LiCoO2 thin films electrodes for lithium rechargeable batteries by a single step method based on an electrochemical-hydrothermal synthesis in a concentrated LiOH solution with a cobalt salt. This process combines the effect of temperature (between 150 deg. C and 200 deg. C), pressure and galvanostatic current. The obtained films were not annealed after the electrochemical-hydrothermal synthesis. For the first time, the theoretical study of the potential-pH diagram of cobalt was carried out at high temperature and high concentration. These calculations show that a pH value higher than 12 is necessary to avoid the direct precipitation of cobalt hydroxide Co(OH)2 inside the solution. An improvement of the soluble species stability with an increase of the temperature and a decrease of the cobalt concentration is predicted. The influence of the deposition conditions (temperature and concentration) at a constant current density was experimentally studied. X-ray diffraction (XRD) shows the formation of well-crystallized LiCoO2 thin films. Raman spectroscopy confirmed the achievement of the electrochemically active R-3m LiCoO2 phase without any trace of the Fd3m phase at temperatures as low as 150 deg. C. Electrochemical measurements demonstrate good performances of the material synthesized between 150 deg. C and 200 deg. C with better capacity retention at higher temperature.

  14. Analýza obchodních a marketingových aktivit společnosti 3M

    Stašová, Jana

    2010-01-01

    The subject of this diploma thesis is besides the general introduction of the 3M Company and the B2B orientation which becomes more and more important nowadays also the practical part in form of situation analysis of the Automotive Aftermarket Division (AAD) as well as its marketing mix. The target market conditions, customer and competitive environment much like available human resources are important factors having influence on the components of the 4P concept. The objective of the thesis i...

  15. Temporal information needs in ResPubliQA: an attempt to improve accuracy. The UC3M Participation at CLEF 2010

    Vicente-Díez, María Teresa; Moreno Schneider, Julián; Paloma MARTÍNEZ

    2010-01-01

    The UC3M team participates in 2010 in the second ResPubliQA evaluation campaign taking part in the monolingual Spanish task. On this occasion we have completely redesigned our Question Answering system, product of multiple efforts while being part of the MIRACLE team, by creating a whole new architecture. The aim was to gain in modularity, flexibility and evaluation capabilities that previous versions left pending. Despite its initial open-domain philosophy, the new system was tes...

  16. Nature of the Darwin term and (Zα)4m3/M2 contribution to the Lamb shift for an arbitrary spin of the nucleus

    The contact Darwin term is demonstrated to be of the same origin as the spin-orbit interactions. The (Zα)4m3/M2 correction to the Lamb shift, generated by the Darwin term, is found for an arbitrary nonvanishing spin of the nucleus, both half-integer and integer. There is also a contribution of the same nature to the nuclear quadrupole moment

  17. c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells.

    Ming, X F; Kaiser, M.; Moroni, C

    1998-01-01

    Whereas signalling pathways involved in transcriptional control have been studied extensively, the pathways regulating mRNA turnover remain poorly understood. We are interested in the role of mRNA stability in cell activation and oncogenesis using PB-3c mast cells as a model system. In these cells the short-lived interleukin-3 (IL-3) mRNA is stabilized by ionomycin treatment and following oncogenesis. To identify the signalling pathways involved in these mechanisms, we analysed the effect of ...

  18. Measurement of the radiative L3-M vacancy transfer probabilities of some 4f elements and compounds using Indus-2 synchrotron radiation

    Krishnananda; Mirji, Santosh; Badiger, N. M.; Tiwari, M. K.

    2016-08-01

    The L X-ray intensity ratios (ILα/ILl, ILα/ILβ, ILα/ILγ) and the radiative L3-M vacancy transfer probabilities (ηL3-M) of some 4f elements such as Gd, Tb, Ho and compounds; Pr2O3, Pr2(CO3)3·8H2O, Nd2O3, Sm2O3, Sm2(CO3)3·2.85H2O, Sm2(SO4)3·8H2O, Gd2(CO3)3, Tb2O3, Dy2(SO4)3, Ho2O3 and HoF3 have been measured using Indus-2 synchrotron radiation. The elements and compounds are excited by synchrotron radiation and the emitted characteristic L X-ray photons are measured with high resolution silicon drift detector. The measured intensity ratios of compounds are not influenced by the chemical environment. However, the ηL3-M values of compound targets indicate the effect of crystal structure.

  19. SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components

    Highlights: ► CHFR mediates the ubiquitination of the major components of the SWI/SNF complex. ► CHFR mediated-ubiquitination induces the degradation of the major components. ► SRG3 stabilizes the SWI/SNF-like BAF complex by blocking the CHFR activity. -- Abstract: The murine SWI/SNF-like BAF complex is an ATP-dependent chromatin remodeling complex that functions as a transcriptional regulator in cell proliferation, differentiation and development. The SWI/SNF-like BAF complex consists of several components including core subunits such as BRG1, BAF155/SRG3, BAF47/SNF5/INI1, and BAF170. We have previously shown that the interaction between SRG3/mBAF155 and other components of the complex stabilizes them by attenuating their proteasomal degradation. However, it has not been known how the major components of the SWI/SNF-like BAF complex such as BRG1, SNF5, and BAF60a are targeted for the ubiquitination and degradation, and how SRG3/mBAF155 protects them from the degradation process. Here we report that CHFR interacts with BRG1, SNF5, and BAF60a of the SWI/SNF-like BAF complex and ubiquitinates them to target for degradation through a proteasome-mediated pathway, and that SRG3/mBAF155 stabilizes these components by blocking their interaction with CHFR.

  20. Ferroelectric and magnetic properties of Aurivillius Bi{sub m+1}Ti{sub 3}Fe{sub m−3}O{sub 3m+3} thin films

    Jia, Tingting, E-mail: jia.tingting@nims.go.jp; Kimura, Hideo, E-mail: KIMURA.Hideo@nims.go.jp [National Institute for Materials Science, 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047 (Japan); Cheng, Zhenxiang [Institute for Superconducting and Electronic Materials, University of Wollongong, Squires Way, North Wollongong, New South Wales 2500 (Australia); Zhao, Hongyang [Department of Materials Science and Engineering, Wuhan Institute of Technology, No. 693 Xiongchu Road, Wuhan 430074 (China)

    2015-11-15

    Aurivillius Bi{sub m+1}Ti{sub 3}Fe{sub m−3}O{sub 3m+3} (m = 4, 5, 6) thin films have been deposited by a pulsed laser deposition system. The x-ray diffraction patterns indicate the formation of orthorhombic phase. The remanent polarization (2P{sub r}) of Bi{sub m+1}Ti{sub 3}Fe{sub m−3}O{sub 3m+3} thin films is decreased with the m-number. Positive-up-negative-down measurements indicate the presence of ferroelectric (FE) polarization in as-obtained thin films. Piezoresponse force microscopy investigations confirm the existence of FE domains and the switchable polarization. Weak magnetic moment is detected in the Aurivillius films at room temperature. The present work suggests the possibility of Aurivillius Bi{sub m+1}Ti{sub 3}Fe{sub m−3}O{sub 3m+3} (m = 4, 5, 6) materials as potential room-temperature multiferroics.

  1. Influence of chisel width on shear bond strength of composite to enamel = Influência da largura do cinzel sobre a resistência ao cisalhamento da união esmalte/resina composta

    Oliveira, Antônio Carlos Castellan de

    2009-01-01

    Objetivo: Avaliar a influência de diferentes larguras de cinzel sobre a resistência de união ao cisalhamento na interface esmalte dental/resina composta. Metodologia: As coroas de 60 dentes incisivos bovinos foram incluídas em resina acrílica e as superfícies vestibulares de esmalte foram planificadas e condicionadas com ácido fosfórico a 35 %. O sistema adesivo Single Bond (3M/ESPE) e de resina composta Z-250 (3M/ESPE) foram utilizados para fabricar restaurações cilíndricas de resina compost...

  2. Expression of CYP2A3 mRNA and its regulation by 3-methylcholanthrene, pyrazole, and ß-ionone in rat tissues

    A.B. Robottom-Ferreira

    2003-07-01

    Full Text Available Cytochrome P450 (CYP 2A enzymes are involved in the metabolism of numerous drugs and hormones and activate different carcinogens. Human CYP2A6, mouse CYP2A5 and rat CYP2A3 are orthologous enzymes that present high similarity in their amino acid sequence and share substrate specificities. However, different from the human and mouse enzyme, CYP2A3 is not expressed in the rat liver. There are limited data about expression of CYP2A3 in extrahepatic tissues and its regulation by typical CYP inducers. Therefore, the objective of the present study was to analyze CYP2A3 mRNA expression in different rat tissues by RT-PCR, and to study the influence of 3-methylcholanthrene, pyrazole and ß-ionone treatment on its expression. Male Wistar rats were divided into four groups of 5 rats each, and were treated ip for 4 days with 3-methylcholanthrene (25 mg/kg body weight, pyrazole (150 mg/kg body weight, ß-ionone (1 g/kg body weight, or vehicle. Total RNA was extracted from tissues and CYP2A3 mRNA levels were analyzed by semiquantitative RT-PCR. CYP2A3 mRNA was constitutively expressed in the esophagus, lung and nasal epithelium, but not along the intestine, liver, or kidney. CYP2A3 mRNA levels were increased in the esophagus by treatment with 3-methylcholanthrene and pyrazole (17- and 7-fold, respectively, in lung by pyrazole and ß-ionone (3- and 4-fold, respectively, although not statistically significant, in the distal part of the intestine and kidney by 3-methylcholanthrene and pyrazole, and in the proximal part of the intestine by pyrazole. CYP2A3 mRNA was not induced in nasal epithelium, liver or in the middle part of the intestine. These data show that, in the rat, CYP2A3 is constitutively expressed in several extrahepatic tissues and its regulation occurs through a complex mechanism that is essentially tissue specific.

  3. 前列腺癌患者手术前后外周血调节性T细胞和FOXP3mRNA的表达及临床意义%Levels of CD4+CD25+Regulatory T Cells & Expression of FOXP3 mRNA after Operation in Peripheral Blood from Patients with Prostate Cancer and its Clinical Significance

    章更生

    2011-01-01

    目的 探讨前列腺癌(Pca)患者手术前后外周血CD4+CD25+调节性T细胞(Tregs)及其特异标志物FOXP3mRNA的表达比例的变化及临床意义.方法 应用流式细胞术检测50例前列腺癌及50例正常对照组外周血单个核细胞(PBMC)中Tregs占CD4+T细胞的比例,应用RT-PCR技术检测人外周血PBMC FOXP3 mRNA的表达.结果 随着Gleason分级升高,CD4+CD25+Tregs/CD4+T比值和FOXP3 mRNA表达量均有升高趋势;Pca患者术前CD4+CD25+ Treg细胞占CD4+T细胞的比例和FOXP3 mRNA表达水平高于正常对照组(均P<0.05),术后水平与正常对照组差异无统计学意义;Pca组Tregs表达率与FOXP3 mRNA呈正相关(r=0.623,P<0.01).结论 Tregs及其特异标志物FOXP3具有维持自身免疫稳定和抑制肿瘤免疫作用,可能参与前列腺癌的发生.%Objective To explore the rate change of CD4+ CD25+ regulatory T cells and expression of F0XP3 mRNA after operation in peripheral blood from patients with prostate cancer and its clinical significance. Methods Flow cytometry was used to analyze the proportion of CD4+CD25+ regulatory T cells/CD4T cells in peripheral blood mononuclear cells (PBMC) among 50 patients with prostate cancer and 50 healthy controls. The expression of FOXP3 mRNA in PBMC was detected by RT-PCR. Results The value of CD4+CU25+Tregs/CD4+ T cells and expression of FOXP3 mRNA were increased with Gleason pathological parameters increased. And the value of CD4+CD25+ regulatory T cells/CD4+T cells and expression of FOXP3 mRNA in PBMC from patients with prostate cancer before operation were significantly higher than that of the healthy controls. But there were no statistical significance between patients with prostate cancer after operation and healthy controls. Correlative analysis showed that there was a positive correlation between the CD4+CD25+ regulatory T cells and the expression of F0XP3 mRNA in PBMC of the patients with prostate cancer (r=0.623,p<0.01). Conclusion CD4+CD25

  4. Diferentes visões sobre a cidade

    Veriano Takuji Miura

    2010-06-01

    Full Text Available A paisagem urbana sempre exerceu um fascínio sobre os homens. Ela tem sido, ao mesmo tempo, sonho e pesadelo de um tempo. Em diferentes momentos, a paisagem urbana tem sido abordada de modo a expressar as singularidades de seu tempo. Nesse sentido, o objetivo deste artigo é trazer uma discussão sobre as diferentes visões da cidade propostas por acadêmicos, cineastas e romancistas. Desde a visão romantizada das cidades da Idade Média, de Ítalo Calvino, até as “cidades virtuais” de Pierre Lévy, destaca-se o longo percurso da chamada “aventura da modernidade”.

  5. El problema de Steklov sobre el cono

    Óscar Andrés Montaño Carreño

    2012-01-01

    Sea (Mn, g) un cono de altura 0 ≤ xn+1 ≤ 1 en R n+1, dotado con una métrica rotacionalmente invariante 2ds2 + f 2 (s)dw2 , donde dw2 representa la métrica estándar sobre S n−1 , la esfera unitaria (n − 1)-dimensional. Supongamos que Ric(g) ≥ 0. En este artículo demostramos que si h > 0 es la curvatura media sobre ∂M y ν1 es el primer valor propio del problema de Steklov, entonces ν1 ≥ h. Abstract. Let (Mn, g) be a cone of height 0 ≤ xn+1 ≤ 1 in R ...

  6. Neopolares de problemas de empaquetamiento sobre semigrupos

    Aráoz Durand, Julián Arturo

    1982-01-01

    Los neopolares permiten caracterizar las caras de un poliedro combinatorio como vértices de poliedros altamente estructurados. Esto sirve para generar planos de cortes y para obtener propiedades duales en problemas de programación entera. Gomory caracterizó neopolares para problemas sobre grupos, Aráoz en "Polyhedral Neopolarities" extendió estos resultados a semigrupos de cubrimiento. En este trabajo se caracterizan neopolares importantes de semigrupos de empaquetamiento que incluyen los pro...

  7. Consideraciones sobre la motricidad del violinista

    Allende, Pablo

    2009-01-01

    Comienza la exposición hablando de que intenta prevenir las patologías en los violinistas mediante secuencias de ejercicios específicos, de diferentes técnicas corporales y fisioterapéuticas. Presenta datos estadísticos sobre el índice de patologías que se encuentran entre estos intérpretes para por último presentar tablas de ejercicios propiamente dichas para intentar paliar estas dolencias

  8. Productos derivados sobre bienes de consumo

    Francisco Venegas Martinez; Salvador Cruz Ake

    2010-01-01

    Este trabajo de investigacion desarrolla un modelo de equilibrio general con expectativas racionales en tiempo continuo util para la determinacion de precios de contratos forward, contratos futuros, bonos cupon cero y opciones europeas (de compra y venta) sobre bienes de consumo. Para ello, el modelo considera un individuo representativo en una economia con dos bienes, los cuales son producidos con tecnologias estocasticas. Por ultimo, el modelo propuesto permite examinar estrategias para obt...

  9. Apuntes sobre la flora gallega, XVII

    Amigo Vázquez, Javier; Pulgar Sañudo, Íñigo

    2005-01-01

    Presentamos un nuevo capítulo dentro de la serie de contribuciones al conocimiento actualizado de la Flora de Galicia, aportando información de interés corológico sobre 11 taxa recolectados: Bidens frondosa L., Crypsis alopecuroides (Piller & Mitterp.) Schrad., Cyperus fuscus L., Cyperus michelianus (L.) Link, Dittrichia graveolens (L.) Desf., Echinochloa crus-galli (L.) P. Beauv. subsp. hispidula (Retz.) Honda, Eragrostis curvula (Schrad.) Nees, Hypericum hirsutum L., Lindernia dubia (L.) Pe...

  10. Reflexiones sobre el concepto de justicia

    Víctor C. Pascual Planchuelo

    2005-06-01

    Full Text Available Este ensayo constituye una reflexión sobre el concepto de Justicia. No se centra, como tantos estudios al respecto, en el plano teórico y metafísico, sino que atiende problemas de mayor actualidad: la opinión de los ciudadanos, la postura de los profesionales y otros asuntos controvertidos del ámbito del Derecho.

  11. First-order ion-optics calculations for an Accelerator Mass Spectrometry system using SRIM and S{sup 3}M

    Gomez-Guzman, J.M., E-mail: jm_gomez@us.es [Centro Nacional de Aceleradores (CNA), Avda. Thomas Alva Edison 7, Isla de la Cartuja, 41092 Seville (Spain); Dpto. de Fisica Atomica, Molecular y Nuclear, University of Seville (Spain); Gomez-Morilla, I. [Technische Universitaet Dresden, Fakultaet Maschinenwesen, Professur fuer Magnetofluiddynamik (Germany); Enamorado-Baez, S.M.; Moreno Suarez, A.I.; Pinto-Gomez, A.R. [Centro Nacional de Aceleradores (CNA), Avda. Thomas Alva Edison 7, Isla de la Cartuja, 41092 Seville (Spain)

    2012-06-15

    In this paper, we describe the transport of a simulated beam, created with the S{sup 3}M beam generation module, along the real beam line of the Accelerator Mass Spectrometry (AMS) facility located at Centro Nacional de Aceleradores (CNA, Seville, Spain). The beam transport through the optical system was determined using the transfer-matrix method, which can easily calculate the beam envelopes without having to track all individual particles, evaluating the ability of such systems and saving computation time. The beam size results given by S{sup 3}M were compared to the real beam size in three of the four image points that the system has (P1, P2 and P3), corresponding with the position of Faradays Cups where the {sup 127}I current was measured, obtaining a good agreement between them. This suggests that the first order approximation model is enough to simulate the optical behavior of the system. It is shown that the beam line has a focusing behavior, minimizing the beam size from {+-}3 mm at the exit of the ion source to {+-}1.09 mm at the detector's entrance window. Using the beam emittance diagram simulations, it is shown that when ions pass through the stripper, the angles of their trajectories are altered by scattering with the gas molecules and the geometrical emittance enlarges, according to Liouville's Theorem. The study presented in this work gives confidence and open new perspectives in simulations with S{sup 3}M in AMS facilities contributing to the understanding of their optical behavior.

  12. Determination of boron in ceramic reference materials by prompt gamma activation analysis using focused neutron guided beam of JRR-3M

    Prompt gamma activation analysis using a focused thermal neutron guided beam at JAEA JRR-3M was applied to the determination of B in ceramic certified reference materials (BAM CRM S-003 Silicon Carbide Powder and NMIJ CRM 8004-a Silicon Nitride Powder). Cl and Si were used as internal standards to obtain linear calibration curves of B. The analytical result of B in BAM CRM S-003 was in good agreement with the certified value. The relative expanded measurement uncertainties (k = 2) were 4.8% for BAM CRM S-003 and 4.9% for NMIJ CRM 8004-a. (author)

  13. Vocación de referente internacional. La UC3M y la Fundación Juan March crean un instituto de Ciencias Sociales

    Gomá, Javier; Sánchez-Cuenca, Ignacio; Peña, Daniel

    2013-01-01

    El pasado 31 de enero Daniel Peña, rector de la UC3M; Javier Gomá, director de la Fundación Juan March; e Ignacio Sánchez-Cuenca, director del Centro de Estudios Avanzados en Ciencias Sociales (CEACS) de dicha fundación, presentaron el Instituto Carlos III – Juan March de Ciencias Sociales. Este nuevo centro mixto tiene la misión de continuar y desarrollar las actividades y la investigación del CEACS y convertirse en un centro de referencia internacional en su ámbito.

  14. Structural and electronic properties of ScnOm (n=1~3, m=1~2n) clusters: Theoretical study using screened hybrid density functional theory

    Yang, Yu; Liu, Haitao; Zhang, Ping

    2011-01-01

    The structural and electronic properties of small scandium oxide clusters ScnOm (n = 1 - 3, m = 1 - 2n) are systematically studied within the screened hybrid density functional theory. It is found that the ground states of these scandium oxide clusters can be obtained by the sequential oxidation of small "core" scandium clusters. The fragmentation analysis demonstrates that the ScO, Sc2O2, Sc2O3, Sc3O3, and Sc3O4 clusters are especially stable. Strong hybridizations between O-2p and Sc-3d orb...

  15. 寻常型银屑病患者外周血单个核细胞SOCS-1、SOCS-3 mRNA的表达%The expression of SOCS-1 and SOCS-3 mRNA in patients with psoriasis vulgaris

    郭红卫; 王京滨; 李国明; 李顺凡; 吴志华

    2007-01-01

    目的: 检测细胞因子信号抑制因子SOCS-1、SOCS-3 mRNA在寻常型银屑病患者外周血单个核细胞(PBMC)中的表达.方法: 从20例银屑病患者及20例健康志愿者外周血中分离PBMC,提取RNA,应用逆转录-聚合酶链反应(RT-PCR)方法检测SOCS-1、SOCS-3 mRNA的表达.结果: SOCS-1、SOCS-3 mRNA在银屑病患者中表达,在正常人中无表达,活动期银屑病患者较静止期患者SOCS-1、SOCS-3 mRNA表达增高.结论: SOCS-1、SOCS-3可能在银屑病的Th1免疫反应中发挥作用.

  16. The expression of DcR3 mRNA in peripheral blood mononuclear cells from patients with Guillain-Barré syndrome%吉兰-巴雷综合征外周血单个核细胞DcR3mRNA表达

    陆嘉茵; 李静; 朱太卿; 田发发; 杨欢; 陈毓茜

    2011-01-01

    Objective To investigate the expression of DcR3 mRNA in peripheral blood mononuclear cells (PBMCs) from patients with Guillain-Barré syndrome (GBS).And to discuss the correlation among cerebrospinal fluid (CSF) -Ig, the severity of GBS and DcR3 mRNA.Methods Thirty-six patients with GBS and 20 healthy controls were included.The expression of DcR3 mRNA in PBMCs was detected by reverse transcription-polymerase chain reaction (RT-PCR).The correlation between the severity of GBS and the expression of DcR3 mRNA was analyzed.The CSF level of CSF-Ig was also analyzed.Results DcR3 mRNA level in GBS patients (0.40 ± 0.08) was significantly higher than in the healthy control (0.17 ± 0.04) (P<0.01).The expression of DcR3 mRNA was comparable between the mild group (0.39 ±0.07) and the severe group (0.41±0.05) (P>0.05).The level of CSF-Ig was also comparable between the mild group [IgG (0.l23 ±0.113) g/L, IgA (0.016± 0.012) g/L, IgM (0.012 ±0.011) g/L]and the severe group [IgG (0.128 ±0.112) g/L, IgA (0.015 ± 0.011) g/L, IgM (0.013±0.013) g/L](P>0.05).There was no correlation between the levels of CSF-Ig and DcR3 mRNA (rIgG = 0.0083, rIgA = 0.0056, rIgM = 0.0015, P> 0.05).Conclusions The expression of DcR3 mRNA in PBMCs increased significantly in GBS patients, indicating that DcR3 could be involved in the pathogenesis of GBS.There was no correlation between GBS severity and DcR3 mRNA level or between CSF-Ig and DcR3 mRNA levels.%目的 研究吉兰-巴雷综合征(Guillain-Barré syndrome,GBS)患者外周血单个核细胞(PBMCs)中凋亡相关基因诱骗受体(DCR3)mRNA的表达水平.探讨DcR3与GBS疾病严重程度及脑脊液免疫球蛋白(CSFIg,包括IgG、IgA、IgM)水平之间的关联性.方法 以36例GBS患者和20名健康人为研究对象,应用反转录聚合酶链反应(RT-PCR)检测外周静脉血PBMCs DcR3 mRNA表达水平,并对GBS患者CSF-Ig水平与疾病严重程度和DcR3 mRNA表达的相关性进行分析.结果 GBS

  17. Pensamiento ciceroniano sobre el rol del ciudadano en la obra “Sobre los deberes”

    Luis Diego Brenes Villalobos

    2013-01-01

    Full Text Available : El ensayo repasa -en los orígenes del republicanismo- el aporte realizado por uno de sus autores clásicos más importante, Marco Tulio Cicerón. En concreto, se revisa la visión de este sobre el rol del ciudadano y el concepto de ciudadanía como intrínsecamente ligada a la República y a la concepción del humanismo. Al efecto, el ensayo se centra en la obra “Sobre los deberes” (De officiis.

  18. Expressions of T-bet, GATA-3, RORγt and FoxP3 mRNA in peripheral blood of patients with allergic asthma%过敏性哮喘患者外周血T-bet、GATA-3、RORγt和FoxP3 mRNA的表达变化

    施宇衡; 时国朝; 马佳韵; 艾香艳; 朱海星; 万欢英

    2011-01-01

    Objective To investigate the expressions of T-bet, GA TA-3, RORγt and FoxP3 mRNA in peripheral blood of patients with allergic asthma. Methods Seventeen patients with mild persistent and 13 patients with moderate-severe persistent house dust mite allergic asthma and 14 healthy controls were enrolled in this study.Expressions of T-bet,GATA-3,RORγt and FoxP3 mRNA in peripheral blood mononuclear cell (PBMC) were determined by quantitative fluorescence PCR. Results Expression of GATA-3 mRNA in mild and moderate-severe asthma patients was significantly higher than that in normal controls (P<0.01). Furthermore, expression of RORγt mRNA in patients with moderate-severe asthma was significantly higher than that in mild asthma patients and normal controls (P<0.01). However, there was no difference in expressions of T-bet and FoxP3 mRNA among these three groups (P>0.05). Conclusions GATA-3 expression was increased in allergic asthma,and RORγt expression was increased in moderate-severe allergic asthma. GA TA-3 and RORγt may play important role in the pathogenesis of allergic asthma.%目的:探讨特异性转录因子T-bet、GATA-3、RORγt和FoxP3 mRNA在过敏性哮喘患者外周血中的表达变化.方法:选择30例慢性持续期的屋尘螨过敏性哮喘患者,其中轻度哮喘17例、中重度哮喘13例,14名正常人作为对照.通过荧光实时定量PCR方法检测3组患者外周血单个核细胞(PBMC)中T-bet、GATA-3、RORγt和FoxP3mRNA的表达.结果:轻度和中重度哮喘患者的GATA-3 mRNA表达均显著高于正常人(均P0.05).结论:过敏性哮喘中GATA-3表达增加,中重度哮喘中RORγt表达增加,GATA-3和RORγt在哮喘发病中起着重要的作用.

  19. Exploring artificial layered heterostructures of LaM'O3/LaM''O3 (M'M''= NiCr, FeCr and NiV).

    Liu, J.; Kareev, M.; Freeland, J. W.; Kareev, A.; Lee, H. N.; Chakhalian, J.

    2008-03-01

    Digital synthesis of atomically sharp interfaces between strongly correlated electron systems can provide a template to build completely new materials. Here we present our results on magnetism and electronic structure in LaM'O3/LaM''O3 (M'M''= NiCr, FeCr and NiV) superlattices by using polarized X-ray spectroscopies. Using laser MBE, the (111) and (100) oriented ultra-thin superlattices were grown with alternating layer thicknesses of 1 unit cell. In the bulk, LaMO3 (M=Cr,Fe,V) are antiferromagnetic insulators while LaNiO3 is a paramagnetic metal. The evolution of element specific magnetism and charge at the interface of LFO/LCO, LNO/LVO and LNO/LCO superlattices with temperature and an applied magnetic field will be discussed in detail. The superlattice results will be contrasted to the bulk magnetic properties of the constituent layers. The work has been supported by U.S. DOD-ARO under Contract No. 0402-17291.

  20. Epidermal growth factor potentiates in vitro metastatic behaviour of human prostate cancer PC-3M cells: involvement of voltage-gated sodium channel

    Uysal-Onganer Pinar

    2007-11-01

    Full Text Available Abstract Background Although a high level of functional voltage-gated sodium channel (VGSC expression has been found in strongly metastatic human and rat prostate cancer (PCa cells, the mechanism(s responsible for the upregulation is unknown. The concentration of epidermal growth factor (EGF, a modulator of ion channels, in the body is highest in prostatic fluid. Thus, EGF could be involved in the VGSC upregulation in PCa. The effects of EGF on VGSC expression in the highly metastatic human PCa PC-3M cell line, which was shown previously to express both functional VGSCs and EGF receptors, were investigated. A quantitative approach, from gene level to cell behaviour, was used. mRNA levels were determined by real-time PCR. Protein expression was studied by Western blots and immunocytochemistry and digital image analysis. Functional assays involved measurements of transverse migration, endocytic membrane activity and Matrigel invasion. Results Exogenous EGF enhanced the cells' in vitro metastatic behaviours (migration, endocytosis and invasion. Endogenous EGF had a similar involvement. EGF increased VGSC Nav1.7 (predominant isoform in PCa mRNA and protein expressions. Co-application of the highly specific VGSC blocker tetrodotoxin (TTX suppressed the effect of EGF on all three metastatic cell behaviours studied. Conclusion 1 EGF has a major involvement in the upregulation of functional VGSC expression in human PCa PC-3M cells. (2 VGSC activity has a significant intermediary role in potentiating effect of EGF in human PCa.

  1. Y chromosome haplotype diversity in Mongolic-speaking populations and gene conversion at the duplicated STR DYS385a,b in haplogroup C3-M407.

    Malyarchuk, Boris A; Derenko, Miroslava; Denisova, Galina; Woźniak, Marcin; Rogalla, Urszula; Dambueva, Irina; Grzybowski, Tomasz

    2016-06-01

    Y chromosome microsatellite (Y-STR) diversity has been studied in different Mongolic-speaking populations from South Siberia, Mongolia, North-East China and East Europe. The results obtained indicate that the Mongolic-speaking populations clustered into two groups, with one group including populations from eastern part of South Siberia and Central Asia (the Buryats, Barghuts and Khamnigans) and the other group including populations from western part of Central Asia and East Europe (the Mongols and Kalmyks). High frequency of haplogroup C3-M407 (>50%) is present in the Buryats, Barghuts and Khamnigans, whereas in the Mongols and Kalmyks its frequency is much lower. In addition, two allelic combinations in DYS385a,b loci of C3-M407 haplotypes have been observed: the combination 11,18 (as well as 11,17 and 11,19) is frequent in different Mongolic-speaking populations, but the 11,11 branch is present mainly in the Kalmyks and Mongols. Results of locus-specific sequencing suggest that the action of gene conversion is a more likely explanation for origin of homoallelic 11,11 combination. Moreover, analysis of median networks of Y-STR haplotypes demonstrates that at least two gene conversion events can be revealed-one of them has probably occurred among the Mongols, and the other event occurred in the Barghuts. These two events give an average gene conversion rate range of 0.24-7.1 × 10(-3) per generation. PMID:26911356

  2. The degree of leukocytosis and urine GATA-3 mRNA levels are risk factors for severe acute kidney injury in Puumala virus nephropathia epidemica.

    Daniel H Libraty

    Full Text Available Puumala hantavirus (PUUV infection, also known as nephropathia epidemica, is the most common cause of hemorrhagic fever with renal syndrome (HFRS in Europe. The pathogenesis of PUUV nephropathia epidemica is complex and multifactorial, and the risk factors for severe acute kidney injury (AKI during acute PUUV infection are not well defined. We conducted a prospective study of hospitalized patients with PUUV infection in Tampere, Finland to identify acute illness risk factors for HFRS severity. Serial daily blood and urine samples were collected throughout acute illness and at 2 week and 6 month convalescent visits. By univariate analyses, the maximum white blood cell count during acute illness was a risk factor for severe AKI. There were no significant associations between PUUV-induced AKI severity and platelet counts, C-reactive protein, or alanine aminotransferase levels. Maximum plasma interleukin (IL-6, urine IL-6, and urine IL-8 concentrations were positively associated with PUUV-induced AKI. Finally, the maximum urinary sediment GATA-3 mRNA level was positively correlated with the peak fold-change in serum creatinine, regardless of AKI severity classification. By multivariate analyses, we found that the maximum levels of leukocytes and urinary sediment GATA-3 mRNA during acute illness were independent risk factors for severe PUUV-induced AKI. We have identified novel acute illness risk factors for severe PUUV-induced AKI.

  3. New rock salt-related oxides Li3M2RuO6 (M=Co, Ni): Synthesis, structure, magnetism and electrochemistry

    We describe the synthesis, crystal structure, magnetic and electrochemical characterization of new rock salt-related oxides of formula, Li3M2RuO6 (M=Co, Ni). The M=Co oxide adopts the LiCoO2 (R-3m) structure, where sheets of LiO6 and (Co2/Ru)O6 octahedra are alternately stacked along the c-direction. The M=Ni oxide also adopts a similar layered structure related to Li2TiO3, where partial mixing of Li and Ni/Ru atoms lowers the symmetry to monoclinic (C2/c). Magnetic susceptibility measurements reveal that in Li3Co2RuO6, the oxidation states of transition metal ions are Co3+ (S=0), Co2+ (S=1/2) and Ru4+ (S=1), all of them in low-spin configuration and at 10 K, the material orders antiferromagnetically. Analogous Li3Ni2RuO6 presents a ferrimagnetic behavior with a Curie temperature of 100 K. The differences in the magnetic behavior have been explained in terms of differences in the crystal structure. Electrochemical studies correlate well with both magnetic properties and crystal structure. Li-transition metal intermixing may be at the origin of the more impeded oxidation of Li3Ni2RuO6 when compared to Li3Co2RuO6. Interestingly high first charge capacities (between ca. 160 and 180 mAh g−1) corresponding to ca. 2/3 of theoretical capacity are reached albeit, in both cases, capacity retention and cyclability are not satisfactory enough to consider these materials as alternatives to LiCoO2. - Graphical abstract: Two new rock salt related oxides of formula, Li3M2RuO6, (M=Co, Ni) have been prepared. The M=Co oxide adopts the LiCoO2 (R-3m) structure and the M=Ni oxide adopts a similar layered structure related to Li2TiO3, monoclinic (C2/c), with partial mixing of Li and Ni/Ru atoms. For Li3Co2RuO6, oxidation state for Ru is 4+ and antiferromagnetic (AFM) order is found below 10 K while for the analogous Li3Ni2RuO6 , Ru oxidation state is 5+ and a ferrimagnetic (FM) behavior with a Curie temperature of 100 K is found. Electrochemical studies correlate well with both

  4. New rock salt-related oxides Li{sub 3}M{sub 2}RuO{sub 6} (M=Co, Ni): Synthesis, structure, magnetism and electrochemistry

    Laha, S. [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560 012 (India); Morán, E., E-mail: emoran@quim.ucm.es [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Sáez-Puche, R.; Alario-Franco, M.Á.; Dos santos-Garcia, A.J. [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Gonzalo, E.; Kuhn, A.; García-Alvarado, F. [Universidad CEU San Pablo, Facultad de Farmacia, Departamento de Química, 28668 Boadilla del Monte, Madrid (Spain); Sivakumar, T.; Tamilarasan, S.; Natarajan, S.; Gopalakrishnan, J. [Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560 012 (India)

    2013-07-15

    We describe the synthesis, crystal structure, magnetic and electrochemical characterization of new rock salt-related oxides of formula, Li{sub 3}M{sub 2}RuO{sub 6} (M=Co, Ni). The M=Co oxide adopts the LiCoO{sub 2} (R-3m) structure, where sheets of LiO{sub 6} and (Co{sub 2}/Ru)O{sub 6} octahedra are alternately stacked along the c-direction. The M=Ni oxide also adopts a similar layered structure related to Li{sub 2}TiO{sub 3}, where partial mixing of Li and Ni/Ru atoms lowers the symmetry to monoclinic (C2/c). Magnetic susceptibility measurements reveal that in Li{sub 3}Co{sub 2}RuO{sub 6}, the oxidation states of transition metal ions are Co{sup 3+} (S=0), Co{sup 2+} (S=1/2) and Ru{sup 4+} (S=1), all of them in low-spin configuration and at 10 K, the material orders antiferromagnetically. Analogous Li{sub 3}Ni{sub 2}RuO{sub 6} presents a ferrimagnetic behavior with a Curie temperature of 100 K. The differences in the magnetic behavior have been explained in terms of differences in the crystal structure. Electrochemical studies correlate well with both magnetic properties and crystal structure. Li-transition metal intermixing may be at the origin of the more impeded oxidation of Li{sub 3}Ni{sub 2}RuO{sub 6} when compared to Li{sub 3}Co{sub 2}RuO{sub 6}. Interestingly high first charge capacities (between ca. 160 and 180 mAh g{sup −1}) corresponding to ca. 2/3 of theoretical capacity are reached albeit, in both cases, capacity retention and cyclability are not satisfactory enough to consider these materials as alternatives to LiCoO{sub 2}. - Graphical abstract: Two new rock salt related oxides of formula, Li{sub 3}M{sub 2}RuO{sub 6}, (M=Co, Ni) have been prepared. The M=Co oxide adopts the LiCoO{sub 2} (R-3m) structure and the M=Ni oxide adopts a similar layered structure related to Li{sub 2}TiO{sub 3,} monoclinic (C2/c), with partial mixing of Li and Ni/Ru atoms. For Li{sub 3}Co{sub 2}RuO{sub 6}, oxidation state for Ru is 4+ and antiferromagnetic (AFM) order is

  5. ALGUNAS CONSIDERACIONES SOBRE GUARDA Y CUIDADO

    Antonio A. Salomón Salomón; Yusleidys Arteaga Gónzalez; Beatriz Figueraz González; Diosbel Fuentes Guilarte

    2011-01-01

    Desde comienzos del segundo tercio del pasado siglo, la mayor parte de los ordenamientos jurídicos se ocuparon de reformar el derecho de familia. Las nuevas concepciones sociales sobre la familia estaban fuertemente inspiradas en el principio de igualdad acogido por la Organización de Naciones unidas. La igualdad de los cónyuges y las relaciones de igualdad de los progenitores respecto a los hijos encontró un respaldo jurídico para fundamentar las reformas del derecho de familia en la igualda...

  6. Productos derivados sobre bienes de consumo

    Francisco Venegas Martínez; Salvador Cruz Ake

    2010-01-01

    Este trabajo de investigación desarrolla un modelo de equilibrio general con expectativas racionales en tiempo continuo útil para la determinación de precios de contratos forward , contratos futuros, bonos cupón cero y opciones europeas (de compra y venta) sobre bienes de consumo. Para ello, el modelo considera un individuo representativo en una economía con dos bienes, los cuales son producidos con tecnologías estocásticas. Por último, el modelo propuesto permite examinar estrategias para o...

  7. Observaciones sobre colostomía

    Escobar T., Jaime; Castro, Augusto de; Peñalosa, Federico

    2011-01-01

    Se hace una revisión sobre 133 casos de colostomías hechas en pacientes del Hospital San Juan de Dios de Bogotá en un período de cinco años; el 43.7 por ciento de los casos eran heridas por arma de fuego. La mortalidad global fue de 16.5 por ciento. La colostomía derivativa, en ASA, ha bajado la mortalidad en las heridas de colon en dicho hospital.

  8. Avances sobre bases de datos no convencionales

    Arroyuelo, Jorge; Esquivel, Susana Cecilia; Grosso, Alejandro; Ludueña, Verónica; Reyes, Nora Susana; Chávez, Edgar; Navarro, Gonzalo

    2014-01-01

    En la actualidad han surgido, debido a los avances alcanzados en tecnologías de información y comunicación, aplicaciones no tradicionales sobre bases de datos de todo tipo de datos, valga la redundancia. Éstos pueden ser imágenes, texto libre, secuencias de ADN, audio, video, etc., pueden estar o no estructurados y provenir de diversas fuentes (satélites, telescopios, revistas, fotografías, música, etc.), como también ser de diferentes tamaños, generalmente muy grandes. Por otro lado, las con...

  9. Literatura infantil sobre problemas infantiles: la diabetes

    Lázaro Fernández, Patricia

    2015-01-01

    Debido al creciente número de casos de diabetes infantil que se está dando en la sociedad actual, no es raro encontrarse en las aulas cada vez más casos de esta enfermedad. Por esta razón, he decidido analizar dos libros sobre esta temática, para hacer un acercamiento del material seleccionado a las aulas y poder desarrollar junto con los niños un aprendizaje colectivo y cooperativo. En este trabajo se expone la importancia de la literatura y la literatura infantil como una ...

  10. Algunas reflexiones sobre la supervivencia empresarial

    Sarabia Alzaga, José María

    1995-01-01

    Dos bloques-tópico, bien conocidos, configuran el esquema lógico de las reflexiones que se proponen. El primero de ellos se centra en nuestra realidad global: el entorno; el segundo, en los impactos que éste ha generado en la empresa, exponiendo una síntesis contrastada -y hoy día vigente- sobre cómo las empresas de éxito están consiguiendo sobrevivir. Como conclusión, se sintetizan algunas ideas o lineas generales de actuación que pudieran ayudar a mejorar o reforzar las propias experiencias...