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Sample records for 2nd european rectal

  1. 2nd European Advanced Accelerator Concepts Workshop

    Assmann, Ralph; Grebenyuk, Julia

    2015-01-01

    The European Advanced Accelerator Concepts Workshop has the mission to discuss and foster methods of beam acceleration with gradients beyond state of the art in operational facilities. The most cost effective and compact methods for generating high energy particle beams shall be reviewed and assessed. This includes diagnostics methods, timing technology, special need for injectors, beam matching, beam dynamics with advanced accelerators and development of adequate simulations. This workshop is organized in the context of the EU-funded European Network for Novel Accelerators (EuroNNAc2), that includes 52 Research Institutes and universities.

  2. European Corporate Law, 2nd edition

    Werlauff, Erik; Dorresteijn, Adriaan; Monteiro, Tiago Pereira;

    As in the First Edition (1995) of this well-known book, the authors demonstrate that analysis and comparison of national corporate laws on a number of issues yield highly valuable general principles and observations, not least because business organisations, wherever located, tend to show a...... fundamentally similar set of legal characteristics. To its original selection of six representative jurisdictions - Belgium, France, Germany, The Netherlands, Spain, and the United Kingdom - the Second Edition now adds Poland, thus including an Eastern European perspective to supplement those of continental...

  3. 2nd European Conference on Data Analysis

    Wilhelm, Adalbert FX

    2016-01-01

    This book offers a snapshot of the state-of-the-art in classification at the interface between statistics, computer science and application fields. The contributions span a broad spectrum, from theoretical developments to practical applications; they all share a strong computational component. The topics addressed are from the following fields: Statistics and Data Analysis; Machine Learning and Knowledge Discovery; Data Analysis in Marketing; Data Analysis in Finance and Economics; Data Analysis in Medicine and the Life Sciences; Data Analysis in the Social, Behavioural, and Health Care Sciences; Data Analysis in Interdisciplinary Domains; Classification and Subject Indexing in Library and Information Science. The book presents selected papers from the Second European Conference on Data Analysis, held at Jacobs University Bremen in July 2014. This conference unites diverse researchers in the pursuit of a common topic, creating truly unique synergies in the process.

  4. 2nd European Congress of Mathematics

    Katona, G; Recski, A; Sza’sz, D

    1998-01-01

    This is the second volume of the procedings of the second European Congress of Mathematics. Volume I presents the speeches delivered at the Congress, the list of lectures, and short summaries of the achievements of the prize winners. Together with volume II it contains a collection of contributions by the invited lecturers. Finally, volume II also presents reports on some of the Round Table discussions. This two-volume set thus gives an overview of the state of the art in many fields of mathematics and is therefore of interest to every professional mathematician. Contributors: Vol. I: N. Alon, L. Ambrosio, K. Astala, R. Benedetti, Ch. Bessenrodt, F. Bethuel, P. Bjørstad, E. Bolthausen, J. Bricmont, A. Kupiainen, D. Burago, L. Caporaso, U. Dierkes, I. Dynnikov, L.H. Eliasson, W.T. Gowers, H. Hedenmalm, A. Huber, J. Kaczorowski, J. Kollár, D.O. Kramkov, A.N. Shiryaev, C. Lescop, R. März. Vol. II: J. Matousek, D. McDuff, A.S. Merkurjev, V. Milman, St. Müller, T. Nowicki, E. Olivieri, E. Scoppola, V.P. Platon...

  5. The 1997 Protocol and the European Union (European Union and '2nd generation' responsibility conventions)

    The issue of accession of the Eastern European Member States to the 1997 Protocol is discussed with focus on the European Union's authority and enforcement powers. Following up the article published in the preceding issue of this journal, the present contribution analyses the relations of the '2nd generation' responsibility conventions to the law of the European Union. (orig.)

  6. 2nd International Afro-European Conference for Industrial Advancement

    Wegrzyn-Wolska, Katarzyna; Hassanien, Aboul; Snasel, Vaclav; Alimi, Adel

    2016-01-01

    This volume contains papers presented at the 2nd International Afro-European Conference for Industrial Advancement -- AECIA 2015. The conference aimed at bringing together the foremost experts and excellent young researchers from Africa, Europe and the rest of the world to disseminate the latest results from various fields of engineering, information, and communication technologies. The topics, discussed at the conference, covered a broad range of domains spanning from ICT and engineering to prediction, modeling, and analysis of complex systems. The 2015 edition of AECIA featured a distinguished special track on prediction, modeling and analysis of complex systems -- Nostradamus, and special sessions on Advances in Image Processing and Colorization and Data Processing, Protocols, and Applications in Wireless Sensor Networks.

  7. 2nd European Conference on Green Power Marketing 2002

    This report summarises the information presented at the European Conference on Green Power Marketing held in 2002 in St. Moritz, Switzerland. It takes a look at the market chances of ecologically produced electricity for use in Switzerland and for export. The opinions of experts from the areas of research, business, politics, marketing and non-governmental organisations that were presented at the meeting are summarised. International perspectives and trends are discussed and strategies and management issues are examined. Product and price policies are discussed, as are instruments for the communication of 'Green Power' issues. Also, issues concerning customer needs, renewable energy sources, climate change and sustainability are dealt with and the situation in Australia is looked at

  8. 2nd European Conference on Geostatistics for Environmental Applications

    Soares, Amílcar; Froidevaux, Roland

    1999-01-01

    The Second European Conference on Geostatistics for Environmental Ap­ plications took place in Valencia, November 18-20, 1998. Two years have past from the first meeting in Lisbon and the geostatistical community has kept active in the environmental field. In these days of congress inflation, we feel that continuity can only be achieved by ensuring quality in the papers. For this reason, all papers in the book have been reviewed by, at least, two referees, and care has been taken to ensure that the reviewer comments have been incorporated in the final version of the manuscript. We are thankful to the members of the scientific committee for their timely review of the scripts. All in all, there are three keynote papers from experts in soil science, climatology and ecology and 43 contributed papers providing a good indication of the status of geostatistics as applied in the environ­ mental field all over the world. We feel now confident that the geoENV conference series, seeded around a coffee table almost six...

  9. Rectal cancer radiotherapy: Towards European consensus

    Background and purpose. During the first decade of the 21st century several important European randomized studies in rectal cancer have been published. In order to help shape clinical practice based on best scientific evidence, the International Conference on 'Multidisciplinary Rectal Cancer Treatment: Looking for an European Consensus' (EURECA-CC2) was organized. This article summarizes the consensus about imaging and radiotherapy of rectal cancer and gives an update until May 2010. Methods. Consensus was achieved using the Delphi method. Eight chapters were identified: epidemiology, diagnostics, pathology, surgery, radiotherapy and chemotherapy, treatment toxicity and quality of life, follow-up, and research questions. Each chapter was subdivided by topic, and a series of statements were developed. Each committee member commented and voted, sentence by sentence three times. Sentences which did not reach agreement after voting round no 2 were openly debated during the Conference in Perugia (Italy) December 2008. The Executive Committee scored percentage consensus based on three categories: 'large consensus', 'moderate consensus', 'minimum consensus'. Results. The total number of the voted sentences was 207. Of the 207, 86% achieved large consensus, 13% achieved moderate consensus, and only three (1%) resulted in minimum consensus. No statement was disagreed by more than 50% of members. All chapters were voted on by at least 75% of the members, and the majority was voted on by >85%. Considerable progress has been made in staging and treatment, including radiation treatment of rectal cancer. Conclusions. This Consensus Conference represents an expertise opinion process that may help shape future programs, investigational protocols, and guidelines for staging and treatment of rectal cancer throughout Europe. In spite of substantial progress, many research challenges remain

  10. 2nd EUROPEAN CONFERENCE ON ELECTROCHEMICAL METHODS APPLIED TO THE CONSERVATION OF ARTWORKS

    Domenech Carbo, Mª Teresa; DOMENECH CARBO, ANTONIO

    2014-01-01

    This book is issued at the occasion of the 2nd European Conference on electrochemical methods applied to the conservation of artworks, held in Valencia, on 23th September, 2014. This Conference has been hosted by the Instituto Universitario de Restauración del Patrimonio of the Universitat Politècnica de València and has been organized under the auspices of the Ministerio de Ciencia e Innovación, the Universitat Politécnica de València, the Universitat de València and the Universisad de Grana...

  11. Public Health Genomics European Network: Report from the 2nd Network Meeting in Rome

    Nicole Rosenkötter

    2007-03-01

    Full Text Available

    Dear Sirs,

    The Public Health Genomics European Network (PHGEN is a mapping exercise for the responsible and effective integration of genome-based knowledge and technologies into public policy and health services for the benefit of population health. In 2005, the European Commission called for a “networking exercise…to lead to an inventory report on genetic determinants relevant for public health”[1], this lead to the funding of a PHGEN three year project (EC project 2005313.This project started in early 2006 with a kick-off meeting in Bielefeld / Germany.The project work is comprised of, according to the public health trias, three one year periods of assessment, policy development and assurance.At the end of the assessment phase a network meeting was held in Rome from January, 31st to February 2nd 2007 with over 90 network members and network observers in attendance. The participants represented different organisations throughout the European Union with expertise in areas such as human genetics and other medical disciplines,epidemiology,public health, law, ethics, political and social sciences. The aim of the meeting was to wrap up the last year’s assessment period and to herald the policy development phase.The assessment period of PHGEN was characterised by several activities: - Contact and cooperation with other European and internationally funded networks and projects on public health genomics or related issues (e.g. EuroGenetest, EUnetHTA, Orphanet, IPTS, PHOEBE, GRaPHInt, P3G - Identification of key experts in public health genomics in the European members states, applicant countries and EFTA/EEA countries from different disciplines (e.g. human genetics and other medical disciplines, public health, law, philosophy, epidemiology, political and social sciences - Building up national task forces on public health genomics in the above mentioned countries - Establishing and work in three working groups: public health genomics

  12. BMI differences in 1st and 2nd generation immigrants of Asian and European origin to Australia.

    Hauck, Katharina; Hollingsworth, Bruce; Morgan, Lawrie

    2011-01-01

    We estimate assimilation of immigrants' body mass index (BMI) to the host population of Australia over one generation, conducting separate analyses for immigrants from 7 regions of Europe and Asia. We use quantile regressions to allow for differing impact of generational status across 19 quantiles of BMI from under-weight to morbidly obese individuals. We find that 1st generation South European immigrants have higher, and South and East Asian immigrants have lower BMI than Australians, but have assimilated to the BMI of their hosts in the 2nd generation. There are no or only small BMI differences between Australians and 1st and 2nd generation immigrants from East Europe, North-West Europe, Middle East and Pacific regions. We conclude that both upward and downward assimilation in some immigrant groups is most likely caused by factors which can change over one generation (such as acculturation), and not factors which would take longer to change (such as genetics). Our results suggest that public health policies targeting the lifestyles of well educated Asian immigrants may be effective in preventing BMI increase in this subgroup. PMID:20869292

  13. IMPACTS OF EUROPEAN BIOFUEL POLICIES ON AGRICULTURAL MARKETS AND ENVIRONMENT UNDER CONSIDERATION OF 2ND GENERATION TECHNOLOGIES AND INTERNATIONAL TRADE

    Becker, A.; ADENÄUER Marcel; Blanco Fonseca, Maria

    2010-01-01

    Even though recent discussions on food prices and indirect land use change point at potential conflicts associated with the production of biofuels the appraisal of biofuels as an effective instrument to slow down climate change and reduce energy dependency still prevails. The EU Renewable Energy Directive (EUROPEAN COMMISSION, 2009) underlines this trend by setting a target of 10% share of energy from renewable sources in the transport sector by 2020. As economic competitiveness of biofuel pr...

  14. Report on the 2nd Florence International Symposium on Advances in Cardiomyopathies: 9th meeting of the European Myocardial and Pericardial Diseases WG of the ESC

    Franco Cecchi

    2012-12-01

    Full Text Available A bridge between clinical and basic science aiming at cross fertilization, with leading experts presenting alongside junior investigators, is the key feature of the “2nd Florence International Symposium on Advances in Cardiomyopathies” , 9th Meeting of the Myocardial and Pericardial Diseases Working Group of the European Society of Cardiology, which was held in Florence, Italy on 26-­-28th September 2012. Patients with cardiomyopathies, with an estimated 3 per thousand prevalence in the general population, constitute an increasingly large proportion of patients seen by most cardiologists. This class of diseases, which are mostly genetically determined with different transmission modalities, can cause important and often unsolved management problems, despite rapid advances in the field. On the other hand, few other areas of cardiology have seen such an impressive contribution from basic science and translational research to the understanding of their pathophysiology and clinical management. The course was designed to constantly promote close interaction between basic science and clinical practice and highlight the top scientific and translational discoveries in this field in 10 scientific sessions. It was preceded by two mini-­-courses, which included the basic concepts of cardiomyocyte mechanical and electrophysiological properties and mechanisms, how-­-to sessions for clinical diagnosis and management and illustrative case study presentations of different cardiomyopathies.

  15. Proceedings of CONCORD 2010: 2nd European Conference on Corporate R&D "An Engine for Growth, a Challenge for European Policy". Academic Forum - Summary Report

    2010-01-01

    The European Commission collects and analyses policy relevant information on corporate R&D through its 'Industrial Research Monitoring and Analysis' [IRMA] activities at the Joint Research Centre's Institute for Prospective Technological Studies [JRC ¿ IPTS], in co-operation with DG Re-search. The EU Industrial R&D Investment Scoreboard, the EU Survey on Business Trends in R&D, as well as the Conferences on Corporate R&D [CONCORD] represent some of the main activities in this regard. Please c...

  16. 2nd Generation Alkaline Electrolysis

    Yde, Lars; Kjartansdóttir, Cecilia Kristin; Allebrod, Frank; Mogensen, Mogens Bjerg; Møller, Per; Hilbert, Lisbeth R.; Nielsen, Peter Tommy; Mathiesen, Troels; Jensen, Jørgen; Andersen, Lars; Dierking, Alexander

    This report provides the results of the 2nd Generation Alkaline Electrolysis project which was initiated in 2008. The project has been conducted from 2009-2012 by a consortium comprising Århus University Business and Social Science – Centre for Energy Technologies (CET (former HIRC)), Technical...

  17. 2nd Tourism Postdisciplinarity Conference

    2016-01-01

    Following the noted success of the 1st international conference on postdisciplinary approaches to tourism studies (held in Neuchatel, Switzerland, 19-22 June, 2013), we are happy to welcome you to the 2nd Tourism Postdisciplinarity Conference. Postdisciplinarity surpasses the boundaries of disciplinary thinking and opens up the possibility to question the established phenomena – touristic or otherwise – we take for granted. It does not claim that disciplinarity is essentially wrong, but it...

  18. Circulating C-Reactive Protein Concentrations and Risks of Colon and Rectal Cancer : A Nested Case-Control Study Within the European Prospective Investigation into Cancer and Nutrition

    Aleksandrova, Krasimira; Jenab, Mazda; Boeing, Heiner; Jansen, Eugene; Bueno-de-Mesquita, H. Bas; Rinaldi, Sabina; Riboli, Elio; Overvad, Kim; Dahm, Christina C.; Olsen, Anja; Tjonneland, Anne; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Francoise; Morois, Sophie; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Kaaks, Rudolf; Rohrmann, Sabine; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; van Duijnhoven, Fraenzel J. B.; Leufkens, Anke M.; Peeters, Petra H.; Rodriguez, Laudina; Bonet, Catalina; Sanchez, Maria-Jose; Dorronsoro, Miren; Navarro, Carmen; Barricarte, Aurelio; Palmqvist, Richard; Hallmans, Goran; Khaw, Kay-Tee; Wareham, Nicholas; Allen, Naomi E.; Spencer, Elizabeth; Romaguera, Dora; Norat, Teresa; Pischon, Tobias

    2010-01-01

    The authors investigated associations between serum C-reactive protein (CRP) concentrations and colon and rectal cancer risk in a nested case-control study within the European Prospective Investigation into Cancer and Nutrition (1992-2003) among 1,096 incident cases and 1,096 controls selected using

  19. 2nd International Conference on Nuclear Physics in Astrophysics

    Fülöp, Zsolt; Somorjai, Endre; The European Physical Journal A : Volume 27, Supplement 1, 2006

    2006-01-01

    Launched in 2004, "Nuclear Physics in Astrophysics" has established itself in a successful topical conference series addressing the forefront of research in the field. This volume contains the selected and refereed papers of the 2nd conference, held in Debrecen in 2005 and reprinted from "The European Physical Journal A - Hadrons and Nuclei".

  20. 2nd Tourism Postdisciplinarity Conference

    Following the noted success of the 1st international conference on postdisciplinary approaches to tourism studies (held in Neuchatel, Switzerland, 19-22 June, 2013), we are happy to welcome you to the 2nd Tourism Postdisciplinarity Conference. Postdisciplinarity surpasses the boundaries of...... study less embedded in that system of thought. Postdisciplinarity is an epistemological endeavour that speaks of knowledge production and the ways in which the world of physical and social phenomena can be known. It is also an ontological discourse as it concerns what we call ‘tourism...

  1. 2nd Historic Mortars Conference

    Hughes, John; Groot, Caspar; Historic Mortars : Characterisation, Assessment and Repair

    2012-01-01

    This volume focuses on research and practical issues connected with mortars on historic structures. The book is divided into four sections: Characterisation of Historic Mortars, Repair Mortars and Design Issues, Experimental Research into Properties of Repair Mortars, and Assessment and Testing. The papers present the latest work of researchers in their field. The individual contributions were selected from the contributions to the 2nd Historic Mortars Conference, which took place in Prague, September, 22-24, 2010. All papers were reviewed and improved as necessary before publication. This peer review process by the editors resulted in the 34 individual contributions included in here. One extra paper reviewing and summarising State-of-the-Art knowledge covered by this publication was added as a starting and navigational point for the reader. The editors believe that having these papers in print is important and they hope that it will stimulate further research into historic mortars and related subjects. 

  2. Morphine Rectal

    Rectal morphine is used to relieve moderate to severe pain. Morphine is in a class of medications called opiate ( ... Rectal morphine comes as a suppository to insert in the rectum. It is usually inserted every 4 hours. Use ...

  3. Abstracts: 2nd interventional MRI symposium

    Anon.

    1997-09-01

    Main topics of the 2nd interventional MRI symposium were: MR compatibility and pulse sequences; MR thermometry, biopsy, musculoskeletal system; laser-induced interstitial thermotherapy, radiofrequency ablations; intraoperative MR; vascular applications, breast, endoscopy; focused ultrasound, cryotherapy, perspectives; poster session with 34 posters described. (AJ)

  4. Abstracts: 2nd interventional MRI symposium

    Main topics of the 2nd interventional MRI symposium were: MR compatibility and pulse sequences; MR thermometry, biopsy, musculoskeletal system; laser-induced interstitial thermotherapy, radiofrequency ablations; intraoperative MR; vascular applications, breast, endoscopy; focused ultrasound, cryotherapy, perspectives; poster session with 34 posters described. (AJ)

  5. Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC).

    Pischon, Tobias; Lahmann, Petra H; Boeing, Heiner; Friedenreich, Christine; Norat, Teresa; Tjønneland, Anne; Halkjaer, Jytte; Overvad, Kim; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Guernec, Gregory; Manuela M Bergmann; Linseisen, Jakob; Becker, Nikolaus; Trichopoulou, Antonia

    2006-01-01

    BACKGROUND: Body weight and body mass index (BMI) are positively related to risk of colon cancer in men, whereas weak or no associations exist in women. This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women. METHODS: We used multivariable adjusted Cox proportional hazards models to examine the association between anthropometric measures and risks of colon and rectal cancer among 368 277 men and women who we...

  6. Evidences in multidisciplinary management of rectal cancer

    In the last 10 years, a number of important European randomized published studies investigated the optimal management of rectal cancer. In order to define an evidence-based approach of the clinical practice based, an international consensus conference was organized in Italy under the endorsement of European Society of Medical Oncology (ESMO), European Society of Surgical Oncology (ESSO) and European Society of Therapeutic Radiation Oncology (ESTRO). The aim of this article is to present highlights of multidisciplinary rectal cancer management and to compare the conclusions of the international conference on 'Multidisciplinary Rectal Cancer Treatment: looking for an European Consensus' (EURECA-CC2) with the new National Comprehensive Cancer Network (NCCN) guidelines. (authors)

  7. 2nd CEAS Specialist Conference on Guidance, Navigation and Control

    Mulder, Bob; Choukroun, Daniel; Kampen, Erik-Jan; Visser, Coen; Looye, Gertjan

    2013-01-01

    Following the successful 1st CEAS (Council of European Aerospace Societies) Specialist Conference on Guidance, Navigation and Control (CEAS EuroGNC) held in Munich, Germany in 2011, Delft University of Technology happily accepted the invitation of organizing the 2nd  CEAS EuroGNC in Delft, The Netherlands in 2013. The goal of the conference is to promote new advances in aerospace GNC theory and technologies for enhancing safety, survivability, efficiency, performance, autonomy and intelligence of aerospace systems using on-board sensing, computing and systems. A great push for new developments in GNC are the ever higher safety and sustainability requirements in aviation. Impressive progress was made in new research fields such as sensor and actuator fault detection and diagnosis, reconfigurable and fault tolerant flight control, online safe flight envelop prediction and protection, online global aerodynamic model identification, online global optimization and flight upset recovery. All of these challenges de...

  8. Diazepam Rectal

    ... the syringe tip into the rectum until the rim is snug against the rectal opening. Slowly count ... Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

  9. Morphological features and molecular markers in rectal cancer from 95 patients included in the European Organisation for Research and Treatment of Cancer 22921 trial: Prognostic value and effects of preoperative radio (chemo) therapy

    Debucquoy, Annelies; Libbrecht, Louis; Roobrouck, Valerie; Goethals, Laurence; McBride, William; Haustermans, Karin

    2008-01-01

    In this study, the prognostic and/or predictive value of different proteins (cyclo-oxygenase 2 (COX-2), Ki67 and cleaved cytokeratin (CK) 18) and fibro-inflammatory changes which might be of importance for the response to treatment were evaluated using tissue micro arrays. Samples were obtained from a subset of 95 patients included in the European Organisation for Research and Treatment of Cancer 22921 clinical trial, which randomised patients with rectal cancer to one of four arms treated wi...

  10. 2nd International Conference on Natural Fibers

    Rana, Sohel

    2016-01-01

    This book collects selected high quality articles submitted to the 2nd International Conference on Natural Fibers (ICNF2015). A wide range of topics is covered related to various aspects of natural fibres such as agriculture, extraction and processing, surface modification and functionalization, advanced structures, nano fibres, composites and nanocomposites, design and product development, applications, market potential, and environmental impact. Divided into separate sections on these various topics, the book presents the latest high quality research work addressing different approaches and techniques to improve processing, performance, functionalities and cost-effectiveness of natural fibre and natural based products, in order to promote their applications in various advanced technical sectors. This book is a useful source of information for materials scientists, teachers and students from various disciplines as well as for R& D staff in industries using natural fibre based materials. .

  11. Second St. Gallen European Organisation for Research and Treatment of Cancer Gastrointestinal Cancer Conference: consensus recommendations on controversial issues in the primary treatment of rectal cancer.

    Lutz, Manfred P; Zalcberg, John R; Glynne-Jones, Rob; Ruers, Theo; Ducreux, Michel; Arnold, Dirk; Aust, Daniela; Brown, Gina; Bujko, Krzysztof; Cunningham, Christopher; Evrard, Serge; Folprecht, Gunnar; Gerard, Jean-Pierre; Habr-Gama, Angelita; Haustermans, Karin; Holm, Torbjörn; Kuhlmann, Koert F; Lordick, Florian; Mentha, Gilles; Moehler, Markus; Nagtegaal, Iris D; Pigazzi, Alessio; Puciarelli, Salvatore; Roth, Arnaud; Rutten, Harm; Schmoll, Hans-Joachim; Sorbye, Halfdan; Van Cutsem, Eric; Weitz, Jürgen; Otto, Florian

    2016-08-01

    Primary treatment of rectal cancer was the focus of the second St. Gallen European Organisation for Research and Treatment of Cancer (EORTC) Gastrointestinal Cancer Conference. In the context of the conference, a multidisciplinary international expert panel discussed and voted on controversial issues which could not be easily answered using published evidence. Main topics included optimal pretherapeutic imaging, indication and type of neoadjuvant treatment, and the treatment strategies in advanced tumours. Here we report the key recommendations and summarise the related evidence. The treatment strategy for localised rectal cancer varies from local excision in early tumours to neoadjuvant radiochemotherapy (RCT) in combination with extended surgery in locally advanced disease. Optimal pretherapeutic staging is a key to any treatment decision. The panel recommended magnetic resonance imaging (MRI) or MRI + endoscopic ultrasonography (EUS) as mandatory staging modalities, except for early T1 cancers with an option for local excision, where EUS in addition to MRI was considered to be most important because of its superior near-field resolution. Primary surgery with total mesorectal excision was recommended by most panellists for some early tumours with limited risk of recurrence (i.e. cT1-2 or cT3a N0 with clear mesorectal fascia on MRI and clearly above the levator muscles), whereas all other stages were considered for multimodal treatment. The consensus panel recommended long-course RCT over short-course radiotherapy for most clinical situations where neoadjuvant treatment is indicated, with the exception of T3a/b N0 tumours where short-course radiotherapy or even no neoadjuvant therapy were regarded to be an option. In patients with potentially resectable tumours and synchronous liver metastases, most panel members did not see an indication to start with classical fluoropyrimidine-based RCT but rather favoured preoperative short-course radiotherapy with systemic

  12. 2nd International Arctic Ungulate Conference

    A. Anonymous

    1996-01-01

    Full Text Available The 2nd International Arctic Ungulate Conference was held 13-17 August 1995 on the University of Alaska Fairbanks campus. The Institute of Arctic Biology and the Alaska Cooperative Fish and Wildlife Research Unit were responsible for organizing the conference with assistance from biologists with state and federal agencies and commercial organizations. David R. Klein was chair of the conference organizing committee. Over 200 people attended the conference, coming from 10 different countries. The United States, Canada, and Norway had the largest representation. The conference included invited lectures; panel discussions, and about 125 contributed papers. There were five technical sessions on Physiology and Body Condition; Habitat Relationships; Population Dynamics and Management; Behavior, Genetics and Evolution; and Reindeer and Muskox Husbandry. Three panel sessions discussed Comparative caribou management strategies; Management of introduced, reestablished, and expanding muskox populations; and Health risks in translocation of arctic ungulates. Invited lectures focused on the physiology and population dynamics of arctic ungulates; contaminants in food chains of arctic ungulates and lessons learned from the Chernobyl accident; and ecosystem level relationships of the Porcupine Caribou Herd.

  13. Exogenous attention enhances 2nd-order contrast sensitivity.

    Barbot, Antoine; Landy, Michael S; Carrasco, Marisa

    2011-05-11

    Natural scenes contain a rich variety of contours that the visual system extracts to segregate the retinal image into perceptually coherent regions. Covert spatial attention helps extract contours by enhancing contrast sensitivity for 1st-order, luminance-defined patterns at attended locations, while reducing sensitivity at unattended locations, relative to neutral attention allocation. However, humans are also sensitive to 2nd-order patterns such as spatial variations of texture, which are predominant in natural scenes and cannot be detected by linear mechanisms. We assess whether and how exogenous attention--the involuntary and transient capture of spatial attention--affects the contrast sensitivity of channels sensitive to 2nd-order, texture-defined patterns. Using 2nd-order, texture-defined stimuli, we demonstrate that exogenous attention increases 2nd-order contrast sensitivity at the attended location, while decreasing it at unattended locations, relative to a neutral condition. By manipulating both 1st- and 2nd-order spatial frequency, we find that the effects of attention depend both on 2nd-order spatial frequency of the stimulus and the observer's 2nd-order spatial resolution at the target location. At parafoveal locations, attention enhances 2nd-order contrast sensitivity to high, but not to low 2nd-order spatial frequencies; at peripheral locations attention also enhances sensitivity to low 2nd-order spatial frequencies. Control experiments rule out the possibility that these effects might be due to an increase in contrast sensitivity at the 1st-order stage of visual processing. Thus, exogenous attention affects 2nd-order contrast sensitivity at both attended and unattended locations. PMID:21356228

  14. Bisacodyl Rectal

    Rectal bisacodyl is used on a short-term basis to treat constipation. It also is used to empty the bowels before surgery and certain medical procedures. Bisacodyl is in a class of medications called stimulant laxatives. It works by increasing activity of the intestines ...

  15. Radical surgery and postoperative radiotherapy as combined treatment in rectal cancer. Final results of a phase III study of the European Organization for Research and Treatment of Cancer

    There is controversy whether adjuvant radiotherapy should be given before or after surgery for locally advanced, resectable rectal cancer. Preoperative radiotherapy substantially reduces local recurrence rates but may increase postoperative complications. In addition, patients found to have early cancers are treated unnecessarily. This study is a randomized trial of postoperative radiotherapy in patients who had a potentially curative resection for locally advanced rectal carcinoma. This trial failed to demonstrate any importance in overall survival or local control when postoperative irradiation was given following resection of locally advanced rectal carcinoma. (author)

  16. Performance and validation of COMPUCEA 2nd generation for uranium measurements in physical inventory verifications

    Full text: In order to somewhat alleviate the kind of logistical problems encountered in the in-field measurements with the current COMPUCEA equipment (COMbined Product for Uranium Content and Enrichment Assay), and with the expected benefits of saving some time and costs for the missions in mind, ITU is presently developing a 2nd generation of the COMPUCEA device. This new development also forms a task in the support programme of the Joint Research Centre of the European Commission to the IAEA. To validate the in-field performance of the newly developed 2nd generation COMPUCEA, a prototype has been tested together with the 1st generation equipment during physical inventory verification (PIV) measurements in different uranium fuel fabrication plants in Europe. In this paper we will present the prototype of COMPUCEA 2nd generation, its hardware as well as the software developed for the evaluation of the U content and 235U enrichment. We will show a comparison of the performance of the 2nd generation with the 1st generation on a larger number of uranium samples measured during the in-field PIVs. The observed excellent performance of the new COMPUCEA represents an important step in the validation of this new instrument. (author)

  17. Florida Investigates 2nd Possible Local Transmission of Zika Virus

    ... html Florida Investigates 2nd Possible Local Transmission of Zika Virus If confirmed, cases would be first instances of ... Broward County, north of Miami. Infection with the Zika virus, which in most cases is transmitted by mosquitoes, ...

  18. PREFACE: 2nd National Conference on Nanotechnology 'NANO 2008'

    Czuba, P.; Kolodziej, J. J.; Konior, J.; Szymonski, M.

    2009-03-01

    This issue of Journal of Physics: Conference Series contains selected papers presented at the 2nd National Conference on Nanotechnology 'NANO2008', that was held in Kraków, Poland, 25-28 June 2008. It was organized jointly by the Polish Chemical Society, Polish Physical Society, Polish Vacuum Society, and the Centre for Nanometer-scale Science and Advanced Materials (NANOSAM) of the Jagiellonian University. The meeting presentations were categorized into the following topics: 1. Nanomechanics and nanotribology 2. Characterization and manipulation in nanoscale 3. Quantum effects in nanostructures 4. Nanostructures on surfaces 5. Applications of nanotechnology in biology and medicine 6. Nanotechnology in education 7. Industrial applications of nanotechnology, presentations of the companies 8. Nanoengineering and nanomaterials (international sessions shared with the fellows of Maria-Curie Host Fellowships within the 6th FP of the European Community Project 'Nano-Engineering for Expertise and Development, NEED') 9. Nanopowders 10. Carbon nanostructures and nanosystems 11. Nanoelectronics and nanophotonics 12. Nanomaterials in catalysis 13. Nanospintronics 14. Ethical, social, and environmental aspects of nanotechnology The Conference was attended by 334 participants. The presentations were delivered as 7 invited plenary lectures, 25 invited topical lectures, 78 oral and 108 poster contributions. Only 1/6 of the contributions presented during the Conference were submitted for publication in this Proceedings volume. From the submitted material, this volume of Journal of Physics: Conference Series contains 37 articles that were positively evaluated by independent referees. The Organizing Committee gratefully acknowledges all these contributions. We also thank all the referees of the papers submitted for the Proceedings for their timely and thorough work. We would like to thank all members of the National Program Committee for their work in the selection process of

  19. ELECTIONS PENSION FUND 2nd candidate

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : FRANDSEN First Name : Poul Kjaer  I have been member of the staff since 1974, and member of staff council for more than 12 years, and my main motivation has been to work for improving the social conditions of the CERN staff. A very important pillar of this is a sound and healthy pension fund. A capitalised scheme has been and still is the best choice for assuring the benefits for the CERN staff, present and future, this social system being part of the whole necessary to attract the best staff to the future High Energy Physics in Europe. However, even the hypothetic close down of the Organisation should allow the benefits to exi...

  20. Thermoluminescent characteristics of ZrO2:Nd films

    In this work it is exposed the obtained results after analysing the photo luminescent and thermoluminescent characteristics of activated zirconium oxide with neodymium (ZrO2 :Nd) and its possible application in the UV radiation dosimetry. The realized experiments had as objective to study the characteristics such as the optimum thermal erased treatment, the influence of light on the response, the response depending on the wavelength, the fadeout of the information, the temperature effect, the response depending on the time and the recurring of the response. The results show that the ZrO2 :Nd is a promising material to be used as Tl dosemeter for the UV radiation. (Author)

  1. A Handbook for Classroom Instruction That Works, 2nd Edition

    Association for Supervision and Curriculum Development, 2012

    2012-01-01

    Perfect for self-help and professional learning communities, this handbook makes it much easier to apply the teaching practices from the ASCD-McREL best-seller "Classroom Instruction That Works: Research-Based Strategies for Increasing Student Achievement, 2nd Edition." The authors take you through the refined Instructional Planning Guide, so you…

  2. 2nd International Conference on Data Management Technologies and Applications

    2013-01-01

    The 2nd International Conference on Data Management Technologies and Applications (DATA) aims to bring together researchers, engineers and practitioners interested on databases, data warehousing, data mining, data management, data security and other aspects of information systems and technology involving advanced applications of data.

  3. The 2nd Seminar on Standardization Cooperation in Northeast Asia

    2004-01-01

    @@ The 2nd Seminar on Standardization Cooperation in Northeast Asia(2003) was held in Beijing from Oct 30th - Oct 31st, which was the succession of the first one in Korea, 2002, with the participants coming from the standardization circles in China, Japan and Korea.

  4. The multidisciplinary rectal cancer treatment: Main convergence s, controversial aspects and investigational areas which support the need for an European Consensus

    Background and purpose: During the past decades staging and treatment of rectal cancer are used different in Europe and in North America. To promote a process to integrate the daily practice with the best evidence of the literature an International Conference was organized in Italy. Agreement between Experts, Centres, and specialists who participated in the Conference are reported. Methods: Five aspects were analyzed and a questionnaire was tailored for this purpose. The questionnaire had 159 questions. During the Conference, at the beginning of each Session, the moderators showed the answers from the Experts and the Centres, and, at the end of the session, the audience voted in all controversial issues. Agreements were scored at three levels: minimum, if it was between 51 and 74% of votes for each group; moderate, between 75 and 94%; large, more than 94%. Results: The main results are: staging: endoanal ultrasound was considered as mandatory in T staging, in the evaluation of sphincter infiltration, and in the restaging of T after chemoradiotherapy (chRT). Magnetic Resonance Imaging is mandatory in the evaluation of mesorectal fascia infiltration. Endoscopy had a moderate agreement for the definition of tumour location, and the barium enema as optional. Digital rectal examination is complementary for staging and PET-CT investigational for T, N and yT staging. Preoperative radiotherapy: for T4 stage chRT was always the preferred treatment, often with moderate agreement, for any tumour location and N status. For T3, chRT received the same agreement except for high location and N0-N1. For T2 stage, N2 and positive nodes outside the mesorectum, chRT received minimum agreement for low and middle tumours; for high tumours only positive nodes outside the mesorectum was agreed upon. Preoperative radiotherapy, negative specimen and sphincter preservation: chRT was agreed by many for all T stages and N presentations of lower third tumours, except for T1-2 N0-N1

  5. 2nd International Conference on Green Communications and Networks 2012

    Ma, Maode; GCN 2012

    2013-01-01

    The objective of the 2nd International Conference on Green Communications and Networks 2012 (GCN 2012) is to facilitate an exchange of information on best practices for the latest research advances in the area of communications, networks and intelligence applications. These mainly involve computer science and engineering, informatics, communications and control, electrical engineering, information computing, and business intelligence and management. Proceedings of the 2nd International Conference on Green Communications and Networks 2012 (GCN 2012) will focus on green information technology and applications, which will provide in-depth insights for engineers and scientists in academia, industry, and government. The book addresses the most innovative research developments including technical challenges, social and economic issues, and presents and discusses the authors’ ideas, experiences, findings, and current projects on all aspects of advanced green information technology and applications. Yuhang Yang is ...

  6. 2nd International Conference on Intelligent Technologies and Engineering Systems

    Chen, Cheng-Yi; Yang, Cheng-Fu

    2014-01-01

    This book includes the original, peer reviewed research papers from the 2nd International Conference on Intelligent Technologies and Engineering Systems (ICITES2013), which took place on December 12-14, 2013 at Cheng Shiu University in Kaohsiung, Taiwan. Topics covered include: laser technology, wireless and mobile networking, lean and agile manufacturing, speech processing, microwave dielectrics, intelligent circuits and systems, 3D graphics, communications, and structure dynamics and control.

  7. Introduction on the 2nd annual general meeting of ARCCNM

    This paper outlines general information on the 2nd annual general meeting of ARCCNM (Asian Regional Cooperative Council for Nuclear Medicine). The international symposium exchanged new development recently on basic and clinical nuclear medicine. Asian school of nuclear medicine is an educational enterprise of ARCCNM, and the objective is to organize and coordinate academic and training programs in nuclear medicine. It will promote nuclear medicine in Asia region through enhancing regional scientific activities and research collaboration

  8. 2nd Interdiciplinary Conference on Production, Logistics and Traffic 2015

    Friedrich, Hanno; Thaller, Carina; Geiger, Christiane

    2016-01-01

    This contributed volume contains the selected and reviewed papers of the 2nd Interdisciplinary Conference on Production, Logistics and Traffic (ICPLT) 2015, Dortmund, Germany. The topical focus lies on economic, ecological and societal issues related to commercial transport. The authors are international experts and the paper collection presents the state-of-the-art in the field, thus making this book a valuable read for both practitioners and researchers.

  9. 2nd International Open and Distance Learning (IODL) Symposium

    Reviewed by Murat BARKAN

    2006-01-01

    This closing remarks prepared and presented by Prof. Dr. Murat BARKAN Anadolu University, Eskisehir, TURKEY DEAR GUESTS, As the 2nd International Open and Distance Learning (IODL) Symposium is now drawing to end, I would like to thank you all for your outstanding speeches, distinguished presentations, constructive roundtable and session discussions, and active participation during the last five days. I hope you all share my view that the whole symposium has been...

  10. Exogenous attention enhances 2nd-order contrast sensitivity

    Barbot, Antoine; Landy, Michael S.; Carrasco, Marisa

    2011-01-01

    Natural scenes contain a rich variety of contours that the visual system extracts to segregrate the retinal image into perceptually coherent regions. Covert spatial attention helps extract contours by enhancing contrast sensitivity for 1st-order, luminance-defined patterns at attended locations, while reducing sensitivity at unattended locations, relative to neutral attention allocation. However, humans are also sensitive to 2nd-order patterns such as spatial variations of texture, which are ...

  11. 2nd International Conference on Electric and Electronics (EEIC 2012)

    Advances in Electric and Electronics

    2012-01-01

    This volume contains 108 full length papers presented at the 2nd International Conference on Electric and Electronics (EEIC 2012), held on April 21-22 in Sanya, China, which brings together researchers working in many different areas of education and learning to foster international collaborations and exchange of new ideas. This volume can be divided into two sections on the basis of the classification of manuscripts considered: the first section deals with Electric and the second section with Electronics.

  12. 2nd International Open and Distance Learning (IODL Symposium

    Reviewed by Murat BARKAN

    2006-10-01

    Full Text Available This closing remarks prepared and presented by Prof. Dr. Murat BARKAN Anadolu University, Eskisehir, TURKEY DEAR GUESTS, As the 2nd International Open and Distance Learning (IODL Symposium is now drawing to end, I would like to thank you all for your outstanding speeches, distinguished presentations, constructive roundtable and session discussions, and active participation during the last five days. I hope you all share my view that the whole symposium has been a very stimulating and successful experience. Also, on behalf of all the participants, I would like to take this opportunity to thank and congratulate the symposium organization committee for their excellent job in organizing and hosting our 2nd meeting. Throughout the symposium, five workshops, six keynote speeches and 66 papers, which were prepared by more than 150 academicians and practitioners from 23 different countries, reflected remarkable and various views and approaches about open and flexible learning. Besides, all these academic endeavors, 13 educational films were displayed during the symposium. The technology exhibition, hosted by seven companies, was very effective to showcase the current level of the technology and the success of applications of theory into practice. Now I would like to go over what our scholar workshop and keynote presenters shared with us: Prof. Marina McIsaac form Arizona State University dwelled on how to determine research topics worthwhile to be examined and how to choose appropriate research design and methods. She gave us clues on how to get articles published in professional journals. Prof. Colin Latchem from Australia and Prof. Dr. Ali Ekrem Ozkul from Anadolu University pointed to the importance of strategic planning for distance and flexible learning. They highlighted the advantages of strategic planning for policy-makers, planners, managers and staff. Dr. Wolfram Laaser from Fern University of Hagen, presented different multimedia clips and

  13. 2nd FP7 Conference and International Summer School Nanotechnology : From Fundamental Research to Innovations

    Yatsenko, Leonid

    2015-01-01

    This book presents some of the latest achievements in nanotechnology and nanomaterials from leading researchers in Ukraine, Europe, and beyond. It features contributions from participants in the 2nd International Summer School “Nanotechnology: From Fundamental Research to Innovations” and International Research and Practice Conference “Nanotechnology and Nanomaterials”, NANO-2013, which were held in Bukovel, Ukraine on August 25-September 1, 2013. These events took place within the framework of the European Commission FP7 project Nanotwinning, and were organized jointly by the Institute of Physics of the National Academy of Sciences of Ukraine, University of Tartu (Estonia), University of Turin (Italy), and Pierre and Marie Curie University (France). Internationally recognized experts from a wide range of universities and research institutions share their knowledge and key results on topics ranging from nanooptics, nanoplasmonics, and interface studies to energy storage and biomedical applications. Pr...

  14. Two 2nd Circuit decisions represent mixed bag on insurance.

    2000-01-21

    The 2nd U.S. Circuit Court of Appeals in New York issued two important rulings within a week on the extent to which the Americans with Disabilities Act (ADA) regulates insurance practices. [Name removed] v. Allstate Life Insurance Co. was a plaintiff-friendly decision, finding that the insurance company illegally refused to sell life insurance to a married couple because of their mental disability, major depression. [Name removed]. v. Israel Discount Bank of New York was more defendant friendly and tackled the issue of whether the ADA permits different benefit caps for mental and physical disabilities. PMID:11367226

  15. BIPHASIC TREATMENT OF 2ND CLASS ANGLE ANOMALIES

    C. Romanec

    2011-09-01

    Full Text Available Our approach aims at presenting, based on clinical observations and complementary examinations, the effects of a treatment’s setting up during the mixed dentition period. The objectives include the identification of the optimal time of treatment of II/1, II/2 Angle malocclusions, as well as the therapeutic possibilities for the treatment of 2nd class Angle malocclusion during the period of mixed and permanent dentition. The study is based on data collected from 114 clinical cases (69 girls and 45 boys with an age span between 7 and 18 years.

  16. 2nd conference on Continuous Media with Microstructure

    Kuczma, Mieczysław

    2016-01-01

    This book presents research advances in the field of Continuous Media with Microstructure and considers the three complementary pillars of mechanical sciences: theory, research and computational simulation. It focuses on the following problems: thermodynamic and mathematical modeling of materials with extensions of classical constitutive laws, single and multicomponent media including modern multifunctional materials, wave propagation, multiscale and multiphysics processes, phase transformations, and porous, granular and composite materials. The book presents the proceedings of the 2nd Conference on Continuous Media with Microstructure, which was held in 2015 in Łagów, Poland, in memory of Prof. Krzysztof Wilmański. .

  17. Afs password expiration starts Feb 2nd 2004

    2004-01-01

    Due to security reasons, and in agreement with CERN management, afs/lxplus passwords will fall into line with Nice/Mail passwords on February 2nd and expire annually. As of the above date afs account holders who have not changed their passwords for over a year will have a 60 day grace period to make a change. Following this date their passwords will become invalid. What does this mean to you? If you have changed your afs password in the past 10 months the only difference is that 60 days before expiration you will receive a warning message. Similar warnings will also appear nearer the time of expiration. If you have not changed your password for more than 10 months, then, as of February 2nd you will have 60 days to change it using the command ‘kpasswd'. Help to choose a good password can be found at: http://security.web.cern.ch/security/passwords/ If you have been given a temporary password at any time by the Helpdesk or registration team this will automatically fall into the expiration category ...

  18. 2nd International Conference on NeuroRehabilitation

    Andersen, Ole; Akay, Metin

    2014-01-01

    The book is the proceedings of the 2nd International Conference on NeuroRehabilitation (ICNR 2014), held 24th-26th June 2014 in Aalborg, Denmark. The conference featured the latest highlights in the emerging and interdisciplinary field of neural rehabilitation engineering and identified important healthcare challenges the scientific community will be faced with in the coming years. Edited and written by leading experts in the field, the book includes keynote papers, regular conference papers, and contributions to special and innovation sessions, covering the following main topics: neuro-rehabilitation applications and solutions for restoring impaired neurological functions; cutting-edge technologies and methods in neuro-rehabilitation; and translational challenges in neuro-rehabilitation. Thanks to its highly interdisciplinary approach, the book will not only be a  highly relevant reference guide for academic researchers, engineers, neurophysiologists, neuroscientists, physicians and physiotherapists workin...

  19. 2nd international conference on advanced nanomaterials and nanotechnology

    Goswami, D; Perumal, A

    2013-01-01

    Nanoscale science and technology have occupied centre stage globally in modern scientific research and discourses in the early twenty first century. The enabling nature of the technology makes it important in modern electronics, computing, materials, healthcare, energy and the environment. This volume contains selected articles presented (as Invited/Oral/Poster presentations) at the 2nd international conference on advanced materials and nanotechnology (ICANN-2011) held recently at the Indian Institute of Technology Guwahati, during Dec 8-10, 2011. The list of topics covered in this proceedings include: Synthesis and self assembly of nanomaterials Nanoscale characterisation Nanophotonics & Nanoelectronics Nanobiotechnology Nanocomposites  F   Nanomagnetism Nanomaterials for Enery Computational Nanotechnology Commercialization of Nanotechnology The conference was represented by around 400 participants from several countries including delegates invited from USA, Germany, Japan, UK, Taiwan, Italy, Singapor...

  20. Isotope effects on vapour phase 2nd viral coefficients

    Vapor phase 2nd virial coefficient isotope effects (VCIE's) are interpreted. A useful correlation ids developed between -Δ(B-b0)/(B-b0) = -VCIE and the reference condensed phase reduced isotopic partition function ratio [ln(fc/fg)]*. B is the second virial coefficient , b0 = 2πσ3/3, σ is the Lennard-Jones size parameter, and Δ is an isotopic difference, light-heavy. [ln(fc/fg)]* can be obtained from vapor pressure isotope effects for T/TCRITICAL p/f2g), where ln(fp/f2g) is the reduced isotopic partition function ratio describing the equilibrium between monomers and interacting pairs. At temperatures well removed from crossovers in ln(fp/f2g) or [ln(fc/fg)]*, ln(fp/f2g) = (0.4±0.2)[ln(fc/fg)]*. (author)

  1. 2nd International Congress on Neurotechnology, Electronics and Informatics

    Encarnação, Pedro

    2016-01-01

    This book is a timely report on current neurotechnology research. It presents a snapshot of the state of the art in the field, discusses current challenges and identifies new directions. The book includes a selection of extended and revised contributions presented at the 2nd International Congress on Neurotechnology, Electronics and Informatics (NEUROTECHNIX 2014), held October 25-26 in Rome, Italy. The chapters are varied: some report on novel theoretical methods for studying neuronal connectivity or neural system behaviour; others report on advanced technologies developed for similar purposes; while further contributions concern new engineering methods and technological tools supporting medical diagnosis and neurorehabilitation. All in all, this book provides graduate students, researchers and practitioners dealing with different aspects of neurotechnologies with a unified view of the field, thus fostering new ideas and research collaborations among groups from different disciplines.

  2. 2nd International Multidisciplinary Microscopy and Microanalysis Congress

    Oral, Ahmet; Ozer, Mehmet

    2015-01-01

    The 2nd International Multidisciplinary Microscopy and Microanalysis Congress & Exhibition (InterM 2014) was held on 16–19 October 2014 in Oludeniz, Fethiye/ Mugla, Turkey. The aim of the congress was to gather scientists from various branches and discuss the latest improvements in the field of microscopy. The focus of the congress has been widened in an "interdisciplinary" manner, so as to allow all scientists working on several related subjects to participate and present their work. These proceedings include 33 peer-reviewed technical papers, submitted by leading academic and research institutions from over 17 countries and representing some of the most cutting-edge research available. The papers were presented at the congress in the following sessions: ·         Applications of Microscopy in the Physical Sciences ·         Applications of Microscopy in the Biological Sciences.

  3. 2nd International Conference on Communication and Computer Engineering

    Othman, Mohd; Othman, Mohd; Rahim, Yahaya; Pee, Naim

    2016-01-01

    This book covers diverse aspects of advanced computer and communication engineering, focusing specifically on industrial and manufacturing theory and applications of electronics, communications, computing and information technology. Experts in research, industry, and academia present the latest developments in technology, describe applications involving cutting-edge communication and computer systems, and explore likely future trends. In addition, a wealth of new algorithms that assist in solving computer and communication engineering problems are presented. The book is based on presentations given at ICOCOE 2015, the 2nd International Conference on Communication and Computer Engineering. It will appeal to a wide range of professionals in the field, including telecommunication engineers, computer engineers and scientists, researchers, academics and students.

  4. 2nd International Conference on Mobile and Wireless Technology

    Wattanapongsakorn, Naruemon

    2015-01-01

    This book provides a snapshot of the current state-of-the-art in the fields of mobile and wireless technology, security and applications.  The proceedings of the 2nd International Conference on Mobile and Wireless Technology (ICMWT2015), it represents the outcome of a unique platform for researchers and practitioners from academia and industry to share cutting-edge developments in the field of mobile and wireless science technology, including those working on data management and mobile security.   The contributions presented here describe the latest academic and industrial research from the international mobile and wireless community.  The scope covers four major topical areas: mobile and wireless networks and applications; security in mobile and wireless technology; mobile data management and applications; and mobile software.  The book will be a valuable reference for current researchers in academia and industry, and a useful resource for graduate-level students working on mobile and wireless technology...

  5. 2nd International Conference on Harmony Search Algorithm

    Geem, Zong

    2016-01-01

    The Harmony Search Algorithm (HSA) is one of the most well-known techniques in the field of soft computing, an important paradigm in the science and engineering community.  This volume, the proceedings of the 2nd International Conference on Harmony Search Algorithm 2015 (ICHSA 2015), brings together contributions describing the latest developments in the field of soft computing with a special focus on HSA techniques. It includes coverage of new methods that have potentially immense application in various fields. Contributed articles cover aspects of the following topics related to the Harmony Search Algorithm: analytical studies; improved, hybrid and multi-objective variants; parameter tuning; and large-scale applications.  The book also contains papers discussing recent advances on the following topics: genetic algorithms; evolutionary strategies; the firefly algorithm and cuckoo search; particle swarm optimization and ant colony optimization; simulated annealing; and local search techniques.   This book ...

  6. 2nd International Conference on Construction and Building Research

    Fernández-Plazaola, Igor; Hidalgo-Delgado, Francisco; Martínez-Valenzuela, María; Medina-Ramón, Francisco; Oliver-Faubel, Inmaculada; Rodríguez-Abad, Isabel; Salandin, Andrea; Sánchez-Grandia, Rafael; Tort-Ausina, Isabel; Construction and Building Research

    2014-01-01

    Many areas of knowledge converge in the building industry and therefore research in this field necessarily involves an interdisciplinary approach. Effective research requires strong relations between a broad variety of scientific and technological domains and more conventional construction or craft processes, while also considering advanced management processes, where all the main actors permanently interact. This publication takes an interdisciplinary approach grouping various studies on the building industry chosen from among the works presented for the 2nd International Conference on Construction and Building Research. The papers examine aspects of materials and building systems; construction technology; energy and sustainability; construction management; heritage, refurbishment and conservation. The information contained within these pages may be of interest to researchers and practitioners in construction and building activities from the academic sphere, as well as public and private sectors.

  7. The 2nd Generation VLTI path to performance

    Woillez, Julien; Berger, Jean-Philippe; Bonnet, Henri; de Wit, Willem-Jan; Egner, Sebastian; Eisenhauer, Frank; Gonté, Frédéric; Guieu, Sylvain; Haguenauer, Pierre; Mérand, Antoine; Pettazzi, Lorenzo; Poupar, Sébastien; Schöller, Markus; Schuhler, Nicolas

    2016-01-01

    The upgrade of the VLTI infrastructure for the 2nd generation instruments is now complete with the transformation of the laboratory, and installation of star separators on both the 1.8-m Auxiliary Telescopes (ATs) and the 8-m Unit Telescopes (UTs). The Gravity fringe tracker has had a full semester of commissioning on the ATs, and a first look at the UTs. The CIAO infrared wavefront sensor is about to demonstrate its performance relative to the visible wavefront sensor MACAO. First astrometric measurements on the ATs and astrometric qualification of the UTs are on-going. Now is a good time to revisit the performance roadmap for VLTI that was initiated in 2014, which aimed at coherently driving the developments of the interferometer, and especially its performance, in support to the new generation of instruments: Gravity and MATISSE.

  8. 2nd Colombian Congress on Computational Biology and Bioinformatics

    Cristancho, Marco; Isaza, Gustavo; Pinzón, Andrés; Rodríguez, Juan

    2014-01-01

    This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.  .

  9. Super Boiler 2nd Generation Technology for Watertube Boilers

    Mr. David Cygan; Dr. Joseph Rabovitser

    2012-03-31

    This report describes Phase I of a proposed two phase project to develop and demonstrate an advanced industrial watertube boiler system with the capability of reaching 94% (HHV) fuel-to-steam efficiency and emissions below 2 ppmv NOx, 2 ppmv CO, and 1 ppmv VOC on natural gas fuel. The boiler design would have the capability to produce >1500 F, >1500 psig superheated steam, burn multiple fuels, and will be 50% smaller/lighter than currently available watertube boilers of similar capacity. This project is built upon the successful Super Boiler project at GTI. In that project that employed a unique two-staged intercooled combustion system and an innovative heat recovery system to reduce NOx to below 5 ppmv and demonstrated fuel-to-steam efficiency of 94% (HHV). This project was carried out under the leadership of GTI with project partners Cleaver-Brooks, Inc., Nebraska Boiler, a Division of Cleaver-Brooks, and Media and Process Technology Inc., and project advisors Georgia Institute of Technology, Alstom Power Inc., Pacific Northwest National Laboratory and Oak Ridge National Laboratory. Phase I of efforts focused on developing 2nd generation boiler concepts and performance modeling; incorporating multi-fuel (natural gas and oil) capabilities; assessing heat recovery, heat transfer and steam superheating approaches; and developing the overall conceptual engineering boiler design. Based on our analysis, the 2nd generation Industrial Watertube Boiler when developed and commercialized, could potentially save 265 trillion Btu and $1.6 billion in fuel costs across U.S. industry through increased efficiency. Its ultra-clean combustion could eliminate 57,000 tons of NOx, 460,000 tons of CO, and 8.8 million tons of CO2 annually from the atmosphere. Reduction in boiler size will bring cost-effective package boilers into a size range previously dominated by more expensive field-erected boilers, benefiting manufacturers and end users through lower capital costs.

  10. Rectal culture (image)

    A rectal culture test is performed by inserting a cotton swab in the rectum. The swab is rotated gently, and withdrawn. A smear of the swab is placed in culture media to encourage the growth of microorganisms. The ...

  11. Understanding Minor Rectal Bleeding

    ... are the possible causes of minor rectal bleeding? Hemorrhoids Anal fissures Proctitis (inflammation of the rectum) Polyps ... can be cured if detected early. What are hemorrhoids? Hemorrhoids (also called piles) are swollen blood vessels ...

  12. Stages of Rectal Cancer

    ... Treatment Genetics of Colorectal Cancer Age and family history can affect the risk of rectal cancer. Anything ... to flow from the body to a collection bag. After the cancer is removed, the surgeon will ...

  13. 2nd International technical meeting on small reactors

    The 2nd International Technical Meeting on Small Reactors was held on November 7-9, 2012 in Ottawa, Ontario. The meeting was hosted by Atomic Energy of Canada Limited (AECL) and Canadian Nuclear Society (CNS). There is growing international interest and activity in the development of small nuclear reactor technology. This meeting provided participants with an opportunity to share ideas and exchange information on new developments. This Technical Meeting covered topics of interest to designers, operators, researchers and analysts involved in the design, development and deployment of small reactors for power generation and research. A special session focussed on small modular reactors (SMR) for generating electricity and process heat, particularly in small grids and remote locations. Following the success of the first Technical Meeting in November 2010, which captured numerous accomplishments of low-power critical facilities and small reactors, the second Technical Meeting was dedicated to the achievements, capabilities, and future prospects of small reactors. This meeting also celebrated the 50th Anniversary of the Nuclear Power Demonstration (NPD) reactor which was the first small reactor (20 MWe) to generate electricity in Canada.

  14. APTWG: 2nd Asia-Pacific Transport Working Group Meeting

    This conference report summarizes the contributions to and discussions at the 2nd Asia-Pacific Transport Working Group Meeting held in Chengdu, China, from 15 to 18 May 2012. The topics of the meeting were organized under five main headings: momentum transport, non-locality in transport, edge turbulence and L–H transition, three-dimensional effects on transport physics, and particle, momentum and heat pinches. It is found that lower hybrid wave and ion cyclotron wave induce co-current rotation while electron cyclotron wave induces counter-current rotation. A four-stage imaging for low (L) to high (H) confinement transition gradually emerges and a more detailed verification is urgently expected. The new edge-localized modes mitigation technique with supersonic molecular beam injection was approved to be effective to some extent on HL-2A and KSTAR. It is also found that low collisionality, trapped electron mode to ion temperature gradient transition (or transition of higher to lower density and temperature gradients), fuelling and lithium coating are in favour of inward pinch of particles in tokamak plasmas. (paper)

  15. Book review: Psychology in a work context (2nd Ed.

    Nanette Tredoux

    2003-10-01

    Full Text Available Bergh, Z. & Theron, A.L. (Eds (2003 Psychology in a work context (2nd Ed.. Cape Town: Oxford University Press. This book is an overview and introduction to Industrial and Organisational Psychology. It is a work of ambitious scope, and it is clear that the contributors have invested a great deal of thought and effort in the planning and execution of the book. The current version is the second edition, and it looks set to become one of those standard textbooks that are revised every few years to keep up with changing times. It is a handsome volume, produced to a high standard of editorial care, pleasingly laid out and organised well enough to be useful as an occasional reference source. An English-Afrikaans glossary, tables of contents for every chapter as well as for the entire book, a comprehensive index and extensive bibliography make it easy to retrieve the information relating to a particular topic. Every chapter ends with a conclusion summarising the gist of the material covered. Quality illustrations lighten the tone and help to bring some of the concepts to life. Learning outcomes and self-assessment exercises and questions for every chapter will be useful to the lecturer using the book as a source for a tutored course, and for the student studying by distance learning. If sold at the suggested retail price, the book represents good value compared to imported textbooks that cover similar ground.

  16. PREFACE: 2nd International Symposium "Optics and its Applications"

    Calvo, Maria L.; Dolganova, Irina N.; Gevorgyan, Narine; Guzman, Angela; Papoyan, Aram; Sarkisyan, Hayk; Yurchenko, Stanislav

    2016-01-01

    The ICTP smr2633: 2nd International Symposium "Optics and its Applications" (OPTICS-2014) http://indico.ictp.it/event/a13253/ was held in Yerevan and Ashtarak, Armenia, on 1-5 September 2014. The Symposium was organized by the Abdus Salam International Center for Theoretical Physics (ICTP) with the collaboration of the SPIE Armenian Student Chapter, the Armenian TC of ICO, the Russian-Armenian University (RAU), the Institute for Physical Research of the National Academy of Sciences of Armenia (IPR of NAS), the Greek-Armenian industrial company LT-Pyrkal, and the Yerevan State University (YSU). The Symposium was co-organized by the BMSTU SPIE & OSA student chapters. The International Symposium OPTICS-2014 was dedicated to the 50th anniversary of the Abdus Salam International Center for Theoretical Physics. This symposium "Optics and its Applications" was the First Official ICTP Scientific Event in Armenia. The presentations at OPTICS-2014 were centered on these topics: optical properties of nanostructures; quantum optics & information; singular optics and its applications; laser spectroscopy; strong field optics; nonlinear & ultrafast optics; photonics & fiber optics; optics of liquid crystals; and mathematical methods in optics.

  17. Development of a Hydrologic Characterization Technology for Fault Zones Phase II 2nd Report

    Karasaki, Kenzi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Doughty, Christine [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gasperikova, Erika [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Peterson, John [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Conrad, Mark [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Cook, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Tiemi, Onishi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-03-31

    This is the 2nd report on the three-year program of the 2nd phase of the NUMO-LBNL collaborative project: Development of Hydrologic Characterization Technology for Fault Zones under NUMO-DOE/LBNL collaboration agreement. As such, this report is a compendium of the results by Kiho et al. (2011) and those by LBNL.

  18. Examples to Accompany "Descriptive Cataloging of Rare Books, 2nd Edition."

    Association of Coll. and Research Libraries, Chicago, IL.

    This book is intended to be used with "Descriptive Cataloging of Rare Books," 2nd edition (DCRB) as an illustrative aid to catalogers and others interested in or needing to interpret rare book cataloging. As such, it is to be used in conjunction with the rules it illustrates, both in DCRB and in "Anglo-American Cataloging Rules," 2nd edition…

  19. Magnetic resonance imaging for the clinical management of rectal cancer patients

    Beets-Tan, Regina G H; Lambregts, Doenja M J; Maas, Monique; Bipat, Shandra; Barbaro, Brunella; Caseiro-Alves, Filipe; Curvo-Semedo, Luís; Fenlon, Helen M; Gollub, Marc J; Gourtsoyianni, Sofia; Halligan, Steve; Hoeffel, Christine; Kim, Seung Ho; Laghi, Andrea; Maier, Andrea; Rafaelsen, Søren R; Stoker, Jaap; Taylor, Stuart A; Torkzad, Michael R; Blomqvist, Lennart

    2013-01-01

    OBJECTIVES: To develop guidelines describing a standardised approach regarding the acquisition, interpretation and reporting of magnetic resonance imaging (MRI) for clinical staging and restaging of rectal cancer. METHODS: A consensus meeting of 14 abdominal imaging experts from the European...

  20. The 2nd Generation Real Time Mission Monitor (RTMM) Development

    Blakeslee, R. J.; Goodman, M.; Hardin, D. M.; Hall, J.; Yubin He, M.; Regner, K.; Conover, H.; Smith, T.; Meyer, P.; Lu, J.; Garrett, M.

    2009-12-01

    The NASA Real Time Mission Monitor (RTMM) is a visualization and information system that fuses multiple Earth science data sources, to enable real time decision-making for airborne and ground validation experiments. Developed at the National Aeronautics and Space Administration (NASA) Marshall Space Flight Center, RTMM is a situational awareness, decision-support system that integrates satellite imagery and orbit data, radar and other surface observations (e.g., lightning location network data), airborne navigation and instrument data sets, model output parameters, and other applicable Earth science data sets. The integration and delivery of this information is made possible using data acquisition systems, network communication links, network server resources, and visualizations through the Google Earth virtual globe application. In order to improve the usefulness and efficiency of the RTMM system, capabilities are being developed to allow the end-user to easily configure RTMM applications based on their mission-specific requirements and objectives. This second generation RTMM is being redesigned to take advantage of the Google plug-in capabilities to run multiple applications in a web browser rather than the original single application Google Earth approach. Currently RTMM employs a limited Service Oriented Architecture approach to enable discovery of mission specific resources. We are expanding the RTMM architecture such that it will more effectively utilize the Open Geospatial Consortium Sensor Web Enablement services and other new technology software tools and components. These modifications and extensions will result in a robust, versatile RTMM system that will greatly increase flexibility of the user to choose which science data sets and support applications to view and/or use. The improvements brought about by RTMM 2nd generation system will provide mission planners and airborne scientists with enhanced decision-making tools and capabilities to more

  1. 2nd interface between ecology and land development in California

    Keeley, Jon E.; Baer-Keeley, Melanie; Fortheringham, C.J.

    2000-01-01

    The 2nd Interface Between Ecology and Land Development Conference was held in association with Earth Day 1997, five years after the first Interface Conference. Rapid population growth in California has intensified the inevitable conflict between land development and preservation of natural ecosystems. Sustainable development requires wise use of diminishing natural resources and, where possible, restoration of damaged landscapes. These Earth Week Celebrations brought together resource managers, scientists, politicians, environmental consultants, and concerned citizens in an effort to improve the communication necessary to maintain our natural biodiversity, ecosystem processes and general quality of life. As discussed by our keynote speaker, Michael Soule, the best predictor of habitat loss is population growth and nowhere is this better illustrated than in California. As urban perimeters expand, the interface between wildlands and urban areas increases. Few problems are more vexing than how to manage the fire prone ecosystems indigenous to California at this urban interface. Today resource managers face increasing challenges of dealing with this problem and the lead-off section of the proceedings considers both the theoretical basis for making decisions related to prescribed burning and the practical application. Habitat fragmentation is an inevitable consequence of development patterns with significant impacts on animal and plant populations. Managers must be increasingly resourceful in dealing with problems of fragmentation and the often inevitable consequences, including susceptibility to invasive oganisms. One approach to dealing with fragmentation problems is through careful landplanning. California is the national leader in the integration of conservation and economics. On Earth Day 1991, Governor Pete Wilson presented an environmental agenda that promised to create between land owners and environmentalists, agreements that would guarantee the protection of

  2. PREFACE: 2nd Workshop on Germanium Detectors and Technologies

    Abt, I.; Majorovits, B.; Keller, C.; Mei, D.; Wang, G.; Wei, W.

    2015-05-01

    The 2nd workshop on Germanium (Ge) detectors and technology was held at the University of South Dakota on September 14-17th 2014, with more than 113 participants from 8 countries, 22 institutions, 15 national laboratories, and 8 companies. The participants represented the following big projects: (1) GERDA and Majorana for the search of neutrinoless double-beta decay (0νββ) (2) SuperCDMS, EDELWEISS, CDEX, and CoGeNT for search of dark matter; (3) TEXONO for sub-keV neutrino physics; (4) AGATA and GRETINA for gamma tracking; (5) AARM and others for low background radiation counting; (5) as well as PNNL and LBNL for applications of Ge detectors in homeland security. All participants have expressed a strong desire on having better understanding of Ge detector performance and advancing Ge technology for large-scale applications. The purpose of this workshop was to leverage the unique aspects of the underground laboratories in the world and the germanium (Ge) crystal growing infrastructure at the University of South Dakota (USD) by brining researchers from several institutions taking part in the Experimental Program to Stimulate Competitive Research (EPSCoR) together with key leaders from international laboratories and prestigious universities, working on the forefront of the intensity to advance underground physics focusing on the searches for dark matter, neutrinoless double-beta decay (0νββ), and neutrino properties. The goal of the workshop was to develop opportunities for EPSCoR institutions to play key roles in the planned world-class research experiments. The workshop was to integrate individual talents and existing research capabilities, from multiple disciplines and multiple institutions, to develop research collaborations, which includes EPSCor institutions from South Dakota, North Dakota, Alabama, Iowa, and South Carolina to support multi-ton scale experiments for future. The topic areas covered in the workshop were: 1) science related to Ge

  3. 2nd U.S. Case of Bacteria Resistant to Last-Resort Antibiotic

    ... news/fullstory_159807.html 2nd U.S. Case of Bacteria Resistant to Last-Resort Antibiotic Scientists concerned it ... the United States who was infected with a bacteria that is resistant to an antibiotic of last ...

  4. Optimized Pump Power Ratio on 2nd Order Pumping Discrete Raman Amplifier

    Renxiang Huang; Youichi Akasaka; David L. Harris; James Pan

    2003-01-01

    By optimizing pump power ratio between 1st order backward pump and 2nd order forward pump on discrete Raman amplifier, we demonstrated over 2dB noise figure improvement without excessive non-linearity degradation.

  5. Combustion synthesis and characterization of Ba2NdSbO6 nanocrystals

    V T Kavitha; R Jose; S Ramakrishna; P R S Wariar; J Koshy

    2011-07-01

    Nanocrystalline Ba2NdSbO6, a complex cubic perovskite metal oxide, powders were synthesized by a self-sustained combustion method employing citric acid. The product was characterized by X-ray diffraction, differential thermal analysis, thermogravimetric analysis, Fourier transform infrared spectroscopy, transmission electron microscopy and scanning electron microscopy. The as-prepared powders were single phase Ba2NdSbO6 and a mixture of polycrystalline spheroidal particles and single crystalline nanorods. The Ba2NdSbO6 sample sintered at 1500°C for 4 h has high density (∼ 95% of theoretical density). Sintered nanocrystalline Ba2NdSbO6 had a dielectric constant of ∼ 21; and dielectric loss = 8 × 10-3 at 5 MHz.

  6. 76 FR 29750 - Filing Dates for the Nevada Special Election in the 2nd Congressional District

    2011-05-23

    ... General Election on September 13, 2011, to fill the U.S. House seat in ] the 2nd Congressional District... report, the first report must cover all activity that occurred before the committee registered as...

  7. 77 FR 75161 - Filing Dates for the Illinois Special Election in the 2nd Congressional District

    2012-12-19

    ... February 26, 2013, and April 9, 2013, to fill the U.S. House seat in the 2nd Congressional District vacated... not previously filed a report, the first report must cover all activity that occurred before...

  8. File list: His.Lar.50.AllAg.2nd_instar [Chip-atlas[Archive

    Full Text Available His.Lar.50.AllAg.2nd_instar dm3 Histone Larvae 2nd instar SRX013015,SRX013042,SRX01...3112,SRX013043,SRX013087,SRX013096 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.50.AllAg.2nd_instar.bed ...

  9. File list: ALL.Lar.10.AllAg.2nd_instar [Chip-atlas[Archive

    Full Text Available ALL.Lar.10.AllAg.2nd_instar dm3 All antigens Larvae 2nd instar SRX013087,SRX013015,...SRX013112,SRX013042,SRX013043,SRX013096,SRX013113,SRX013016,SRX013114 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.10.AllAg.2nd_instar.bed ...

  10. File list: His.Lar.05.AllAg.2nd_instar [Chip-atlas[Archive

    Full Text Available His.Lar.05.AllAg.2nd_instar dm3 Histone Larvae 2nd instar SRX013087,SRX013096,SRX01...3043,SRX013015,SRX013112,SRX013042 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.05.AllAg.2nd_instar.bed ...

  11. File list: His.Lar.20.AllAg.2nd_instar [Chip-atlas[Archive

    Full Text Available His.Lar.20.AllAg.2nd_instar dm3 Histone Larvae 2nd instar SRX013015,SRX013042,SRX01...3112,SRX013043,SRX013096,SRX013087 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.20.AllAg.2nd_instar.bed ...

  12. File list: ALL.Lar.20.AllAg.2nd_instar [Chip-atlas[Archive

    Full Text Available ALL.Lar.20.AllAg.2nd_instar dm3 All antigens Larvae 2nd instar SRX013015,SRX013042,...SRX013112,SRX013043,SRX013016,SRX013114,SRX013096,SRX013087,SRX013113 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.20.AllAg.2nd_instar.bed ...

  13. File list: ALL.Lar.50.AllAg.2nd_instar [Chip-atlas[Archive

    Full Text Available ALL.Lar.50.AllAg.2nd_instar dm3 All antigens Larvae 2nd instar SRX013015,SRX013042,...SRX013112,SRX013016,SRX013114,SRX013043,SRX013087,SRX013096,SRX013113 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.50.AllAg.2nd_instar.bed ...

  14. From 1st- to 2nd-Generation Biofuel Technologies: Extended Executive Summary

    NONE

    2008-07-01

    This report looks at the technical challenges facing 2nd-generation biofuels, evaluates their costs and examines related current policies to support their development and deployment. The potential for production of more advanced biofuels is also discussed. Although significant progress continues to be made to overcome the technical and economic challenges, 2nd-generation biofuels still face major constraints to their commercial deployment.

  15. [Laparoscopic rectal resection technique].

    Anthuber, M; Kriening, B; Schrempf, M; Geißler, B; Märkl, B; Rüth, S

    2016-07-01

    The quality of radical oncological operations for patients with rectal cancer determines the rate of local recurrence and long-term survival. Neoadjuvant chemoradiotherapy for locally advanced tumors, a standardized surgical procedure for rectal tumors less than 12 cm from the anus with total mesorectal excision (TME) and preservation of the autonomous nerve system for sexual and bladder function have significantly improved the oncological results and quality of life of patients. The TME procedure for rectal resection has been performed laparoscopically in Germany for almost 20 years; however, no reliable data are available on the frequency of laparoscopic procedures in rectal cancer patients in Germany. The rate of minimally invasive procedures is estimated to be less than 20 %. A prerequisite for using the laparoscopic approach is implicit adherence to the described standards of open surgery. Available data from prospective randomized trials, systematic reviews and meta-analyses indicate that in the early postoperative phase the generally well-known positive effects of the minimally invasive approach to the benefit of patients can be realized without any long-term negative impact on the oncological results; however, the results of many of these studies are difficult to interpret because it could not be confirmed whether the hospitals and surgeons involved had successfully completed the learning curve. In this article we would like to present our technique, which we have developed over the past 17 years in more than 1000 patients. Based on our experiences the laparoscopic approach can be highly recommended as a suitable alternative to the open procedure. PMID:27277556

  16. 2nd Symposium on applied nuclear physics and innovative technologies

    2014-01-01

    Symposium on Applied Nuclear Physics and Innovative Technologies will be held for the second time at Collegium Maius, the oldest building of the Jagiellonian University in Cracow, the same building where Nicolaus Copernicus has studied astronomy. Symposium is organized in the framework of the MPD programme carried out by the Foundation for Polish science based on the European Structural Funds. The aim of this conference is to gather together young scientists and experts in the field of applied and fundamental nuclear as well as particle physics. Aiming at interplay of fundamental and applied science the conference will be devoted to the following topics: * Medical imaging and radiotherapy * New materials and technologies in radiation detection * Fission, fusion and spallation processes * High-performance signal processing and data analysis * Tests of foundations of physics and search for a new kind of sub-atomic matter

  17. 2nd Iberian Nuclear Astrophysics Meeting on Compact Stars

    Perez-Garcia, M. Angeles; Pons, Jose; Albertus, C.

    2012-02-01

    ORGANIZING COMMITTEE Dr M Ángeles Pérez-García (Área Física Teórica-Universidad de Salamanca & IUFFYM) Dr J A Miralles (Universidad de Alicante) Dr J Pons (Universidad de Alicante) Dr C Albertus (Área Física Nuclear-Universidad de Salamanca & IUFFYM) Dr F Atrio (Área Física Teórica-Universidad de Salamanca & IUFFYM) PREFACE The second Iberian Nuclear Astrophysics meeting was held at the University of Salamanca, Spain on 22-23 September 2011. This volume contains most of the presentations delivered at this international workshop. This meeting was the second in the series following the previous I Encuentro Ibérico de Compstar, held at the University of Coimbra, Portugal in 2010. The main purpose of this meeting was to strengthen the scientific collaboration between the participants of the Iberian and the rest of the southern European branches of the European Nuclear Astrophysics network, formerly, COMPSTAR. This ESF (European Science Foundation) supported network has been crucial in helping to make a broader audience for the the most interesting and relevant research lines being developed currently in Nuclear Astrophysics, especially related to the physics of neutron stars. It is indeed important to emphasize the need for a collaborative approach to the rest of the scientific communities so that we can reach possible new members in this interdisciplinary area and as outreach for the general public. The program of the meeting was tailored to theoretical descriptions of the physics of neutron stars although some input from experimental observers and other condensed matter and optics areas of interest was also included. The main scientific topics included: Magnetic fields in compact stars Nuclear structure and in-medium effects in nuclear interaction Equation of state: from nuclear matter to quarks Importance of crust in the evolution of neutron stars Computational simulations of collapsing dense objects Observational phenomenology In particular, leading

  18. Strategies for 2nd generation biofuels in EU - Co-firing to stimulate feedstock supply development and process integration to improve energy efficiency and economic competitiveness

    The present biofuel policies in the European Union primarily stimulate 1st generation biofuels that are produced based on conventional food crops. They may be a distraction from lignocellulose based 2nd generation biofuels - and also from biomass use for heat and electricity - by keeping farmers' attention and significant investments focusing on first generation biofuels and the cultivation of conventional food crops as feedstocks. This article presents two strategies that can contribute to the development of 2nd generation biofuels based on lignocellulosic feedstocks. The integration of gasification-based biofuel plants in district heating systems is one option for increasing the energy efficiency and improving the economic competitiveness of such biofuels. Another option, biomass co-firing with coal, generates high-efficiency biomass electricity and reduces CO2 emissions by replacing coal. It also offers a near-term market for lignocellulosic biomass, which can stimulate development of supply systems for biomass also suitable as feedstock for 2nd generation biofuels. Regardless of the long-term priorities of biomass use for energy, the stimulation of lignocellulosic biomass production by development of near term and cost-effective markets is judged to be a no-regrets strategy for Europe. Strategies that induce a relevant development and exploit existing energy infrastructures in order to reduce risk and reach lower costs, are proposed an attractive complement the present and prospective biofuel policies. (author)

  19. Strategies for 2nd generation biofuels in EU - Co-firing to stimulate feedstock supply development and process integration to improve energy efficiency and economic competitiveness

    The present biofuel policies in the European Union primarily stimulate 1st generation biofuels that are produced based on conventional food crops. They may be a distraction from lignocellulose based 2nd generation biofuels - and also from biomass use for heat and electricity - by keeping farmers' attention and significant investments focusing on first generation biofuels and the cultivation of conventional food crops as feedstocks. This article presents two strategies that can contribute to the development of 2nd generation biofuels based on lignocellulosic feedstocks. The integration of gasification-based biofuel plants in district heating systems is one option for increasing the energy efficiency and improving the economic competitiveness of such biofuels. Another option, biomass co-firing with coal, generates high-efficiency biomass electricity and reduces CO2 emissions by replacing coal. It also offers a near-term market for lignocellulosic biomass, which can stimulate development of supply systems for biomass also suitable as feedstock for 2nd generation biofuels. Regardless of the long-term priorities of biomass use for energy, the stimulation of lignocellulosic biomass production by development of near term and cost-effective markets is judged to be a no-regrets strategy for Europe. Strategies that induce a relevant development and exploit existing energy infrastructures in order to reduce risk and reach lower costs, are proposed an attractive complement the present and prospective biofuel policies.

  20. Breast metastases from rectal carcinoma

    LI Jia; FANG Yu; LI Ang; LI Fei

    2011-01-01

    Metastases to the breast from extramammary neoplasms are very rare, constituting 2.7% of all malignant breast tumours. The most common primary tumor metastatic to the breast is primary breast cancer. Rectal cancer metastasizing to the breast is extremely rare. We report a case of aggressive rectal carcinoma with metastasis to the breast.

  1. MRI of rectal stromal tumour

    Dam, Claus; Lindebjerg, Jan; Rafaelsen, Søren Rafael

    2012-01-01

    aware of for the rectal multidisciplinary team. On suspicion of GIST, patients should be referred to a sarcoma centre. The diagnosis of rectal GIST can be suggested on MRI by the presence of a well-defined heterogeneously large mass with a necrotic center associated with a prominent extra...

  2. Rectal carcinoids: a systematic review.

    McDermott, Frank D

    2014-07-01

    Rectal carcinoids are increasing in incidence worldwide. Frequently thought of as a relatively benign condition, there are limited data regarding optimal treatment strategies for both localized and more advanced disease. The aim of this study was to summarize published experiences with rectal carcinoids and to present the most current data.

  3. Monitoring North Korea Explosions: Status and Result of 1st and 2nd Tests (Invited)

    Chi, H.; Lee, H.; Shin, J.; Park, J.; Sheen, D.; Kim, G.; Che, I.; Lim, I.; Kim, T.

    2009-12-01

    Through data exchanging with China, Russia and Japan, KIGAM could monitor North Korea explosion tests in near real time with azimuthal full coverage from the test site. Except for the East Sea (Japan Sea) side, the seismic stations are distributed uniformly along the boundaries of North Korea and adjacent countries, and only stations with the distance of 200 to 550 Km from the test site were considered. Irrespective of azimuthal directions of stations from the test site, the conventional discrimination, Pn/Lg spectral ratio clearly showed that both tests were explosion. But mb-Ms discrimination did not show apparently the known pattern of explosion for both tests. Body wave magnitude, mb(Pn) of 2nd test, which was evaluated as 4.5 by KIGAM, varies with directional location of stations widely from 4.1 to 5.2. The magnitude obtained from Lg, mb(Lg), showed narrow variation between 4.3 to 4.7 with the average of 4.5. In the case of 1st test, both mb(Pn) and mb(Lg) showed equivalently large variation with directional station location. The error ellipses of epicentral determination of test site for 1st and 2nd tests showed almost identical pattern if they were separately calculated with the same configuration of stations. But the combined use of 1st and 2nd test data showed that 2nd test site was moved approximately 2 Km westward from 1st site. The cut-off frequencies of P wave of 1st and 2nd tests showed no or negligible difference even though the estimated yield of 2nd test were much larger than that of 1st one. The ratio of 1st and 2nd P-wave amplitudes showed from 2 to 3.1 times. Correspondingly the estimated energy or yield were ranged from 4 to roughly 10 times. KIGAM evaluated the yield of 2nd test were 8 times in the average larger than that of 1st one.

  4. Regional Observations of North Korea Explosions: 1st and 2nd Tests

    Chi, Heon Cheol; Shin, Jin Soo; Lee, Hee-Il; Park, Jung Ho; Sheen, Dong-Hoon; Kim, Geunyoung; Kim, Tea Sung; Che, Il-Young; Lim, In-Seub

    2010-05-01

    Through data exchanging with China, Russia and Japan, KIGAM could monitor North Korea explosion tests in near real time with azimuthally full coverage from the test site. Except for the East Sea (Japan Sea) side, the seismic stations are distributed uniformly along the boundaries of North Korea and adjacent countries. The error ellipses of epicentral determination of test site for 1st and 2nd tests showed almost identical pattern if they were separately calculated with the same configuration of stations. But the combined use of the 1st and the 2nd test data showed that the 2nd test site was moved approximately 2 Km westward from 1st site. The Pn/Lg spectral ratio clearly discriminate these events from two nearby natural earthquakes above 4 Hz. Full moment tensor inversion also indicate the 2nd test had a very large isotropic component. But mb-Ms discrimination, which has been considered one of the most reliable discriminants for separating explosions and earthquakes, did not show apparently the known pattern of explosion for both tests. Body wave magnitude, mb(Pn) of the 2nd test, which was evaluated as 4.5 by KIGAM, varies with directional location of stations widely from 4.1 to 5.2. The magnitude obtained from Lg, mb(Lg), showed narrow variation between 4.3 to 4.7 with the average of 4.5. In the case of both 1st and 2nd tests, both mb(Pn) and mb(Lg) showed equivalently large variation with directional station location. These variations are mainly due to lateral variation of crustal structures surrounding the test site. Remarkably mb(Lg) showed very linear relationship with mb(Pn). By considering attenuation characteristics according to the propagation path, the variations could be effectively reduced. The cut-off frequencies of P wave of both tests showed no or negligible difference even though the estimated yield of the 2nd test were much larger than that of the 1st one. The ratio of P-wave amplitudes of two tests showed from 2 to 3.1 times. Correspondingly the

  5. Intergenerational Transmission and the School-to-work Transition for 2nd Generation Immigrants

    Nielsen, Helena Skyt; Rosholm, Michael; Smith, Nina;

    2001-01-01

    We analyse the extent of intergenerational transmission through parental capital, ethnic capital and neighbourhood effects on several aspects of the school-to-work transition of 2nd generation immigrants and young ethnic Danes. The main findings are that parental capital has strong positive effects...... on the probability of completing a qualifying education and on the entry into the labour market, but it has a much smaller impact on the duration of the first employment spell and on the wage level. Growing up in neighbourhoods with a high concentration of immigrants is associated with negative...... labour market prospects both for young natives and 2nd generation immigrants....

  6. Advances in Sustainability: Contributions and Outcomes of the 2nd World Sustainability Forum

    Sylvie Flämig

    2013-03-01

    Full Text Available After a successful start in 2011, the 2nd World Sustainability Forum (WSF was held on sciforum.net from 1–30 November 2012. More than 80 papers were presented and over 180 authors contributed to the multidisciplinary conference. The objective of this short report is to sum up the contributions and discussions of the 2nd World Sustainability Forum. It is organized as follows. First, some general information on the Forum is given, then a summary of the contributions to the different sections, as well as providing an overview of the discussions. A final section including an outlook to the 3rd World Sustainability Forum concludes the article.

  7. Advances in Sustainability: Contributions and Outcomes of the 2nd World Sustainability Forum

    Sylvie Flämig; Marc A. Rosen

    2013-01-01

    After a successful start in 2011, the 2nd World Sustainability Forum (WSF) was held on sciforum.net from 1–30 November 2012. More than 80 papers were presented and over 180 authors contributed to the multidisciplinary conference. The objective of this short report is to sum up the contributions and discussions of the 2nd World Sustainability Forum. It is organized as follows. First, some general information on the Forum is given, then a summary of the contributions to the different sections...

  8. Rectal injuries following radiation therapy

    Rectal injuries following radiation therapy were reviewed. Primary diseases in which radiation injuries appeared were described, and local injuries in the neibouring organs such as the small intestine, the bladder, the uterus, and the vagina were also referred to. Classification, frequency, fistulation, radiation necrosis, x-ray findings and occurrence time of rectal and sigmoid colonic injuries were reported. As occurrence factors of radiation injuries, total dose, measurement of dose, stage of primary disease, and history of laparatomy were mentioned. Countermeasures for reducing rectal injuries and treatment methods of local injuries were also described. (Serizawa, K.)

  9. The Effect of Using Computer Edutainment on Developing 2nd Primary Graders' Writing Skills

    Mohammed Abdel Raheem, Azza Ashraf

    2011-01-01

    The present study attempted to examine the effect of using computer edutainment on developing 2nd graders' writing skills. The study comprised thirty-second year primary stage enrolled in Bani Hamad primary governmental school, Minia governorate. The study adopted the quasi-experimental design. Thirty participants were randomly assigned to one…

  10. Proceedings of the 2nd symposium on valves for coal conversion and utilization

    Maxfield, D.A. (ed.)

    1981-01-01

    The 2nd symposium on valves for coal conversion and utilization was held October 15 to 17, 1980. It was sponsored by the US Department of Energy, Morgantown Energy Technology Center, in cooperation with the Valve Manufacturers Association. Seventeen papers have been entered individually into EDB and ERA. (LTN)

  11. Introductory statement to the 2nd scientific forum on sustainable development: A role for nuclear power?

    In his Introductory Statement to the 2nd Scientific Forum on 'Sustainable Development - A Role for Nuclear Power?' (Vienna, 28 September 1999), the Director General of the IAEA focussed on the the main aspects concerning the development of nuclear power: safety, competitiveness, and public support

  12. Intergenerational Transmission and the School-to-work Transition for 2nd Generation Immigrants

    Nielsen, Helena Skyt; Rosholm, Michael; Smith, Nina;

    2001-01-01

    We analyse the extent of intergenerational transmission through parental capital, ethnic capital and neighbourhood effects on several aspects of the school-to-work transition of 2nd generation immigrants and young ethnic Danes. The main findings are that parental capital has strong positive effects...

  13. Proceedings of the 2nd Mediterranean Conference on Information Technology Applications (ITA '97)

    This is the proceedings of the 2nd Mediterranean Conference on Information Technology Applications, held in Nicosia, Cyprus, between 6-7 November, 1997. It contains 16 papers. Two of these fall within the scope of INIS and are dealing with Telemetry, Radiation Monitoring, Environment Monitoring, Radiation Accidents, Air Pollution Monitoring, Diagnosis, Computers, Radiology and Data Processing

  14. The 2nd Global Space Development Summit Held In Washington DC

    Bian Ji

    2009-01-01

    @@ The 2nd Global Space Development Summit,organized by the Center for Strategic and International Studies in partnership with the American Institute of Aeronautics and Astronautics, the Space Foundation and the Chinese Society of Astronautics (CSA), took place in Washington, D.C. On November 12-13.

  15. 2nd International Congress on Economics and Business – New Economic Trends and Business Opportunities

    ARIK, Nazlı

    2016-01-01

    Abstract. In this study, the evaluation of The 2nd International Congress On Economics And Business: New Economic Trends and Business Opportunities held on May 30- June 3, 2016 in Sarajevo will be mentioned.Keywords. Economics, Economic Trends, Business Opportunities,  Labour Relations, Financial economics.JEL. M10, M20, O10.

  16. Stem cells and cancer immunotherapy: Arrowhead’s 2nd annual cancer immunotherapy conference

    Bot, Adrian; Chiriva-Internati, Maurizio; Cornforth, Andrew; Brian J Czerniecki; Ferrone, Soldano; Geles, Kenneth; Greenberg, Philip D.; Hurt, Elaine; Koya, Richard C.; Masoud H Manjili; Matsui, William; Morgan, Richard A.; Palena, Claudia M; Powell Jr, Daniel J; Restifo, Nicholas P

    2014-01-01

    Investigators from academia and industry gathered on April 4 and 5, 2013, in Washington DC at the Arrowhead’s 2nd Annual Cancer Immunotherapy Conference. Two complementary concepts were discussed: cancer “stem cells” as targets and therapeutic platforms based on stem cells.

  17. Mash-Up Personal Learning Environments. Proceedings of the 2nd Workshop MUPPLE’09

    Wild, Fridolin; Kalz, Marco; Palmér, Matthias; Müller, Daniel

    2009-01-01

    Wild, F., Kalz, M., Palmér, M., & Müller, D. (Eds.). (2009). Mash-Up Personal Learning Environments. Proceedings of the 2nd Workshop MUPPLE’09. September, 29, 2009, Nice, France: CEUR Workshop Proceedings, online http://sunsite.informatik.rwth-aachen.de/Publications/CEUR-WS/Vol-506/

  18. General Information about Rectal Cancer

    ... Treatment Genetics of Colorectal Cancer Age and family history can affect the risk of rectal cancer. Anything ... to flow from the body to a collection bag. After the cancer is removed, the surgeon will ...

  19. Treatment Option Overview (Rectal Cancer)

    ... Treatment Genetics of Colorectal Cancer Age and family history can affect the risk of rectal cancer. Anything ... to flow from the body to a collection bag. After the cancer is removed, the surgeon will ...

  20. Rectal examination in general practice.

    Hennigan, T W; Franks, P. J.; Hocken, D. B.; Allen-Mersh, T. G.

    1990-01-01

    OBJECTIVE--To investigate factors influencing a general practitioner's decision to do a rectal examination in patients with anorectal or urinary symptoms. DESIGN--Postal questionnaire survey. SETTING--General practices in inner London and Devon. SUBJECTS--859 General practitioners, 609 (71%) of whom returned the questionnaire. MAIN OUTCOME MEASURES--Number of rectal examinations done each month; the indication score, derived from answers to a question asking whether the respondent would do a ...

  1. Early rectal stenosis following stapled rectal mucosectomy for hemorrhoids

    Schuster Anja

    2004-05-01

    Full Text Available Abstract Background Within the last years, stapled rectal mucosectomy (SRM has become a widely accepted procedure for second and third degree hemorrhoids. One of the delayed complications is a stenosis of the lower rectum. In order to evaluate the specific problem of rectal stenosis following SRM we reviewed our data with special respect to potential predictive factors or stenotic events. Methods A retrospective analysis of 419 consecutive patients, which underwent SRM from December 1998 to August 2003 was performed. Only patients with at least one follow-up check were evaluated, thus the analysis includes 289 patients with a mean follow-up of 281 days (±18 days. For statistic analysis the groups with and without stenosis were evaluated using the Chi-Square Test, using the Kaplan-Meier statistic the actuarial incidence for rectal stenosis was plotted. Results Rectal stenosis was observed in 9 patients (3.1%, eight of these stenoses were detected within the first 100 days after surgery; the median time to stenosis was 95 days. Only one patient had a rectal stenosis after more than one year. 8 of the 9 patients had no obstructive symptoms, however the remaining patients complained of obstructive defecation and underwent surgery for transanal strictureplasty with electrocautery. A statistical analysis revealed that patients with stenosis had significantly more often prior treatment for hemorrhoids (p Conclusion Rectal stenosis is an uncommon event after SRM. Early stenosis will occur within the first three months after surgery. The majority of the stenoses are without clinical relevance. Only one of nine patients had to undergo surgery for a relevant stenosis. The predictive factor for stenosis in the patient-characteristics is previous interventions for hemorrhoids, severe postoperative pain might also predict rectal stenosis.

  2. Individual Differences In The School Performance of 2nd-Grade Children Born to Low-Income Adolescent Mothers

    Apiwattanalunggarn, Kunlakarn Lekskul; Luster, Tom

    2005-01-01

    The purpose of this study was to investigate factors that contribute to individual differences in the school performance of 2nd-grade children born to adolescent mothers. The sample of this study was 90 low-income adolescent mothers and their children. Data were collected from the adolescent mothers and their first-born children, now in 2nd grade,…

  3. Crystal structures and phase transformation of deuterated lithium imide, Li{sub 2}ND

    Balogh, Michael P. [Chemical and Environmental Sciences Laboratory, General Motors Research and Development Center, 30500 Mound Road, Warren, MI 48090-9055 (United States)]. E-mail: michael.p.balogh@gm.com; Jones, Camille Y. [NIST Center for Neutron Research, 100 Bureau Drive, Stop 8562, National Institute of Standards and Technology, Gaithersburg, MD 20899-8562 (United States); Herbst, J.F. [Materials and Processes Laboratory, General Motors Research and Development Center, 30500 Mound Road, Warren, MI 48090-9055 (United States); Hector, Louis G. [Materials and Processes Laboratory, General Motors Research and Development Center, 30500 Mound Road, Warren, MI 48090-9055 (United States); Kundrat, Matthew [Aerotek Corp., 26211 Central Park Blvd., Southfield, MI 48076 (United States)

    2006-08-31

    We have investigated the crystal structure of deuterated lithium imide, Li{sub 2}ND, by means of neutron and X-ray diffraction. An order-disorder transition occurs near 360K. Below that temperature Li{sub 2}ND can be described to the same level of accuracy as a disordered cubic (Fd3-bar m) structure with partially occupied Li 32e sites or as a fully occupied orthorhombic (Ima2 or Imm2) structure. The high temperature phase is best characterized as disordered cubic (Fm3-bar m) with D atoms randomized over the 192l sites. Density functional theory calculations complement and support the diffraction analyses. We compare our findings in detail with previous studies.

  4. Crystal structures and phase transformation of deuterated lithium imide, Li2ND

    We have investigated the crystal structure of deuterated lithium imide, Li2ND, by means of neutron and X-ray diffraction. An order-disorder transition occurs near 360K. Below that temperature Li2ND can be described to the same level of accuracy as a disordered cubic (Fd3-bar m) structure with partially occupied Li 32e sites or as a fully occupied orthorhombic (Ima2 or Imm2) structure. The high temperature phase is best characterized as disordered cubic (Fm3-bar m) with D atoms randomized over the 192l sites. Density functional theory calculations complement and support the diffraction analyses. We compare our findings in detail with previous studies

  5. Revised data for 2nd version of nuclear criticality safety handbook/data collection

    This paper outlines the data prepared for the 2nd version of Data Collection of the Nuclear Criticality Safety Handbook. These data are discussed in the order of its preliminary table of contents. The nuclear characteristic parameters (k∞, M2, D) were derived, and subcriticality judgment graphs were drawn for eleven kinds of fuels which were often encountered in criticality safety evaluation of fuel cycle facilities. For calculation of criticality data, benchmark calculations using the combination of the continuous energy Monte Carlo criticality code MVP and the Japanese Evaluated Nuclear Data Library JENDL-3.2 were made. The calculation errors were evaluated for this combination. The implementation of the experimental results obtained by using NUCEF facilities into the 2nd version of the Data Collection is under discussion. Therefore, related data were just mentioned. A database is being prepared to retrieve revised data easily. (author)

  6. Analysis of plume oxidation during the air pollution episode of September 2nd 1998

    Harrison, R.M.; Baggot, S.

    2001-08-01

    This study was commissioned by the Environment Agency in order to provide further investigation into the air pollution episode of September 2nd, 1998 which afflicted parts of the Midlands and South Yorkshire. A report by the Environment Agency based upon numerical modelling by the Meteorological Office indicated a number of major industrial facilities as the source of the emissions responsible for the episode. In this report an investigation is made of likely chemical changes during airmass transport and its impact on air composition at ground-level and downwind receptor locations. It is concluded that the measurements of air quality at Nottingham Centre, Stoke on Trent and Birmingham Centre on 2nd September 1998 are consistent with emissions from the sources identified in the Environment Agency report on this episode when allowance is made for oxidation of sulphur and nitrogen oxides within the plume. 3 refs., 9 figs., 9 tabs.

  7. Caries correction factors applied to a Punic (6th - 2nd BC) population from Ibiza (Spain)

    Márquez-Grant, N

    2009-01-01

    Caries correction factors were applied to a Punic (6th-2nd century BC) rural sample from the island of Ibiza (Spain). Data obtained on dental caries and ante-mortem tooth loss provided a corrected rate of 12.8% of teeth with caries. This result, in conjunction with other sources of information such as stable isotope analysis and documentary evidence, indicated a diet based on terrestrial protein (mainly carbohydrates) and a low component of marine protein. The paper suggests further research ...

  8. 2006: 2nd Jameson - D.I.T Faculty of Tourism and Food Cocktail Competition

    Murphy, James Peter

    2006-01-01

    The 2nd Jameson - D.I.T Faculty of Tourism and Food Cocktail Competition took place on Thursday November 30th 2006, this initiative between the Faculty of Tourism and Food and Jameson offered over 60 hospitality and bartending students currently studying and working in the hospitality and licensed trade industries the opportunity to improve their skills in creative drinks mixing, in direct response to the growing demand for new cocktails and exciting new drinks to suit every season. Overall p...

  9. Protection of Architectural Heritage in Latvia, the 2nd Half of the 19th Century - 1940

    Mintaurs, Mārtiņš

    2008-01-01

    ANNOTATION The dissertation “Protection of Architectural Heritage in Latvia, the 2nd Half of the 19th Century – 1940” created at the University of Latvia, Department of Archaeology and Ancillary Historical Disciplines of the Faculty of History and Philosophy in 2007 by Martins Mintaurs under the guidance of associated professor Aleksandrs Gavrilins, Dr. hist. The dissertation includes introduction, examination of sources and bibliography, three chapters, conclusion, index of...

  10. Production of artificial ionospheric layers by frequency sweeping near the 2nd gyroharmonic

    Pedersen, T.; M. McCarrick; Reinisch, B.; Watkins, B.; Hamel, R.; Paznukhov, V.

    2011-01-01

    Artificial ionospheric plasmas descending from the background F-region have been observed on multiple occasions at the High Frequency Active Auroral Research Program (HAARP) facility since it reached full 3.6 MW power. Proximity of the transmitter frequency to the 2nd harmonic of the electron gyrofrequency (2fce) has been noted as a requirement for their occurrence, and their disappearance after only a few minutes has been attributed to the increasing...

  11. Group field theory as the 2nd quantization of Loop Quantum Gravity

    Oriti, Daniele

    2013-01-01

    We construct a 2nd quantized reformulation of canonical Loop Quantum Gravity at both kinematical and dynamical level, in terms of a Fock space of spin networks, and show in full generality that it leads directly to the Group Field Theory formalism. In particular, we show the correspondence between canonical LQG dynamics and GFT dynamics leading to a specific GFT model from any definition of quantum canonical dynamics of spin networks. We exemplify the correspondence of dynamics in the specifi...

  12. Study on self-medication among 2nd year medical students

    K. Jagadeesh; K. N. Chidananda; Sreenivas P. Revankar; Nagaraja S. Prasad

    2015-01-01

    Background: Self-medication is use of medicines by individuals to treat self-recognized symptoms and illness. Self-medication is a common type of self-care behavior in the general public, but medical students differ in such practice, as they have knowledge about drugs and diseases. Methods: The present study involved 100 2nd year final term medical students in and ldquo;Shivamogga Institute of Medical Sciences, and rdquo; Shivamogga, Karnataka. Study was questionnaire based, and the resul...

  13. Standardization and Innovation The 2nd Shenzhen Hi-tech Standardization Forum Held

    Huang Manxue; Huang Li

    2006-01-01

    @@ "The 2nd Shenzhen Hi-tech Standardization Forum"was fulfilled in Shenzhen Civil Center on November 25th,2005. The forum lasted for two days. There were around 400 delegates from enterprises and standardization organizations participating in this forum. Nine experts from standardization, intellectual property organizations and enterprises made their excellent speeches focusing on the topic "Standardardization and Innovation". All participates agreed that standardization improves innovation efficiently.

  14. Archaeometric study of glass beads from the 2nd century BC cemetery of Numantia

    García Heras, Manuel; Rincoón López, Jesús M.; Alfredo JIMENO MARTÍNEZ; Villegas Broncano, María Angeles

    2003-01-01

    Recent archaeologícalf ieldwork undertaken in the Celtiberian cremation necropolis of Numantia (Soria, Spain) has provided a group of glass beads from the 2nd century BC. Such glass beads were part, together with other metallic and ceramic items, of the offerings deposited with the dead. They are ring-shaped in typology and deep-blue, amber, or semitransparent white in colour. This paper reports results derived from the chemical and microstructural characterization carried out on a representa...

  15. City look package: the 2nd Summer Youth Olympic Games : Nanjing 2014

    2016-01-01

    The City Look Package of the 2nd Summer Youth Olympic Games (hereinafter referred to as "Nanjing 2014") is the package of designs developed to decorate the host city during Games time, comprised of usage guidelines for combinations of fundamental elements inside the city, including core graphics, emblem, slogan and so on. As a result, it is the most important guiding document in design and implementation of the city Look. In order to protect the authenticity, integrity and consistency of the ...

  16. A ZeroDimensional Model of a 2nd Generation Planar SOFC Using Calibrated Parameters

    Brian Elmegaard; Niels Houbak; Thomas Frank Petersen

    2006-01-01

    This paper presents a zero-dimensional mathematical model of a planar 2nd generation coflow SOFC developed for simulation of power systems. The model accounts for the electrochemical oxidation of hydrogen as well as the methane reforming reaction and the water-gas shift reaction. An important part of the paper is the electrochemical sub-model, where experimental data was used to calibrate specific parameters. The SOFC model was implemented in the DNA simulation software which is designed for ...

  17. A Communications Guide for Sustainable Development: How Interested Parties Become Partners, 2nd Edition

    Fowler, Kimberly M.; Hund, Gretchen; Engel-Cox, Jill A.

    2016-03-06

    The 2nd edition is an updated version plus an e-book. This book was developed to assist organizations in designing and managing their communication and stakeholder involvement programs. The guidebook describes a step-by-step approach, provides case studies, and presents tools to consider. The book uses a scenario approach to outline changes an organization may confront, and provides a menu of communication and engagement activities that support organizational decision making.

  18. Idaho National Laboratory Quarterly Performance Analysis for the 2nd Quarter FY 2015

    Mitchell, Lisbeth A. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-04-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of events for the 2nd Qtr FY-15.

  19. Drugs Approved for Colon and Rectal Cancer

    ... Professionals Questions to Ask about Your Treatment Research Drugs Approved for Colon and Rectal Cancer This page ... and rectal cancer that are not listed here. Drugs Approved for Colon Cancer Avastin (Bevacizumab) Bevacizumab Camptosar ( ...

  20. Application research on enhancing near-infrared micro-imaging quality by 2nd derivative

    Wang, Dong; Ma, Zhi-hong; Zhao, Liu; Wang, Bei-hong; Han, Ping; Pan, Li-gang; Wang, Ji-hua

    2013-08-01

    Near-infrared micro-imaging will not only provide the sample's spatial distribution information, but also the spectroscopic information of each pixel. In this thesis, it took the artificial sample of wheat flour and formaldehyde sodium sulfoxylate distribution given for example to research the data processing method for enhancing the quality of near-infrared micro-imaging. Near-infrared spectroscopic feature of wheat flour and formaldehyde sodium sulfoxylate being studied on, compare correlation imaging and 2nd derivative imaging were applied in the imaging processing of the near-infrared micro-image of the artificial sample. Furthermore, the two methods were combined, i.e. 2nd derivative compare correlation imaging was acquired. The result indicated that the difference of the correlation coefficients between the two substances, i.e. wheat flour and formaldehyde sodium sulfoxylate, and the reference spectrum has been increased from 0.001 in compare correlation image to 0.796 in 2nd derivative compare correlation image respectively, which enhances the imaging quality efficiently. This study will, to some extent, be of important reference significance to near-infrared micro-imaging method research of agricultural products and foods.

  1. IQGAP1 in rectal adenocarcinomas

    Holck, Susanne; Nielsen, Hans Jørgen; Hammer, Emilie;

    2015-01-01

    Treatment of rectal adenocarcinoma includes total mesorectal excision, which is preceded by radiochemotherapy (RCT) in cases of advanced disease. The response to RCT varies from total tumor regression to no effect but this heterogeneous response is unexplained. However, both radiation and treatment...... with 5-fluorouracil may induce treatment resistance through upregulation of the mitogen-activated protein kinase (MAPK) cascade. IQGAP1 is a scaffold protein that appears to be essential to MAPK signaling in cancers. We have therefore studied IQGAP1 protein expression in rectal adenocarcinomas before...

  2. Wavelength and oscillator strength of dipole transition 1s22p-1s2nd for Mn22+ ion

    WANG ZhiWen; WANG YaNan; HU MuHong; LI XinRu; LIU Ying

    2008-01-01

    The transition energies, wavelengths and dipole oscillator strengths of 1s22p-1s2nd (3≤n≤9) for Mn22+. ion are calculated. The fine structure splittings of 1s2nd (n ≤9) states for this ion are also evaluated. In calculating energy, the higher-order relativistic contribution is estimated under a hydrogenic approximation. The quantum defect of Rydberg series 1s2nd is determined according to the quantum defect theory. The results obtained in this paper excellently agree with the experi-mental data available in literatures.

  3. Thrombosed hemorrhoid mimicking rectal carcinoma at CT

    Ben-Chetrit, E.; Bar-Ziv, J. (Dept. of Medicine, Dept. of Radiology, Hadassah Univ. Hospital, Jerusalem (Israel))

    1992-09-01

    A 46-year-old male with cirrhosis and portal hypertension complained of lower pelvic pain. CT of the rectum raised a strong suspicion of a rectal tumor. However, rectal examination, anoscopy, direct rectoscopy, and, unfortunately, post-mortem dissection, failed to confirm its existence. Nevertheless, large flat hemorrhoids were evident. Review of the patient's chart disclosed the presence of large thrombosed hemorrhoids detected by rectal examination prior to the CT examination. It is suggested that rectal hemorrhoids be included in the differential diagnosis of rectal tumor shown by CT in patients with portal hypertension. (orig.).

  4. Thrombosed hemorrhoid mimicking rectal carcinoma at CT

    A 46-year-old male with cirrhosis and portal hypertension complained of lower pelvic pain. CT of the rectum raised a strong suspicion of a rectal tumor. However, rectal examination, anoscopy, direct rectoscopy, and, unfortunately, post-mortem dissection, failed to confirm its existence. Nevertheless, large flat hemorrhoids were evident. Review of the patient's chart disclosed the presence of large thrombosed hemorrhoids detected by rectal examination prior to the CT examination. It is suggested that rectal hemorrhoids be included in the differential diagnosis of rectal tumor shown by CT in patients with portal hypertension. (orig.)

  5. Penile metastasis from rectal carcinoma

    Murhekar K

    2007-01-01

    Full Text Available Penile metastases are infrequent and often originate from genitor-urinary organs including bladder and prostate. In the present communication, we report an unusual case of penile metastasis from rectal adenocarcinoma. Though uncommon, this presentation is not unknown. A review of literature of penile metastases in colorectal cancers is also summarized here.

  6. THE PLACE OF MECHANIC SUTURES IN MEDIUM AND LOW RECTAL CANCER

    C. Oprescu

    2013-03-01

    Full Text Available BACKGROUND: For medium and low rectal cancer the most common surgical procedures are: low anterior resection with mechanical or manual colorectal anastomosis and transanal rectosigmiod resection with abdominoendoanal intubation. METHODS: We have conducted an observational, retrospective single-center study on a number of consecutive patients operated between January 1st and June 31st, 2011 for malign pathology of the middle and low rectum in The Clinical Emergency Hospital Bucuresti. We included patients with medium and low rectal cancer who had been previously treated by radiotherapy. We practiced rectal resection with mechanical colorectal anastomosis or abdominoendoanal intubation with anal mucous membrane removal. We assessed a number of parameters in relation to surgical procedure, such as: anastomosis dehiscence (AD, anastomotic stenosis (AS, the number of defecations in 24 hours, nocturnal incontinence, delayed bowel movement, flatulence continence, postoperative complications, local tumour recurrence and mortality. RESULTS: The study comprises 53 patients divided into 2 groups: the 1st group, included 19 patients treated by rectal resection with abdominoendoanal intubation and anal mucous membrane removal, and the 2nd group, included 34 patients treated by rectal resection with mechanical colorectal anastomosis. AD was found in 5.26% (1/19 in group 1, respectively 20.5% (7/34 in group nr 2. At 6 months follow-up, one patient from the 1st group experienced AS (5.26%, as for the 2nd group, AS was present in 5 patients (14.7%; at 12 months after the procedure the number of patients with AS increased to 3 in group 1 (15.78% and to 6 in group 2 (17.64% respectively. After 12 months, the nocturnal incontinence evaluated between 11.00 pm and 06.00 am: 3 patients from group 1 had 1 night evacuation daily, in all days of the week; 1 patient from group 2 presented 2 night evacuations on week. After 12 months postoperative: 11 patients, (57

  7. Estructura cristalina del nuevo óxido tipo perovskita compleja Ba2NdZrO5,5

    D.A. Landínez Téllez

    2007-01-01

    Full Text Available A new complex perovskite material Ba2NdZrO5;5has been synthesized for the first time by a conventional solid state reaction process. X–raydiffraction (XRD measurements and Rietveld analysis revealed an ordered complex cubic structure characteristic of A2BB0O6crystallinestructure with a lattice constanta= 8;40ß0;01̊A. Energy Dispersive X–ray (EDX analysis shows that Ba2NdZrO5;5is free of impuritytraces. Preliminary studies reveal that at820±C temperature Ba2NdZrO5;5does not react with YBa2Cu3O7°±. These favorable characteristicsof Ba2NdZrO5;5show that it can be used as a potential substrate material for fabrication of superconducting films.

  8. Transition energy and dipole oscillator strength for 1s22p-1s2nd of Cr21+ ion

    Wang Zhi-Wen; Liu Ying; Hu Mu-Hong; Li Xin-Ru; Wang Ya-Nan

    2008-01-01

    The transition energies, wavelengths and dipole oscillator strengths of 1s22p-1s2nd (3 ≤ n ≤ 9) for Cr21+ ion are calculated. The fine structure splittings of 1s2nd (n ≤ 9) states for this ion are also calculated. In calculating energy, we have estimated the higher-order relativistic contribution under a hydrogenic approximation. The quantum defect of Rydberg series 1s2nd is determined according to the quantum defect theory. The results obtained in this paper excellently agree with the experimental data available in the literature. Combining the quantum defect theory with the discrete oscillator strengths, the discrete oscillator strengths for the transitions from initial state 1s22p to highly excited 1s2nd states (n ≥ 10) and the oscillator strength density corresponding to the bound-free transitions are obtained.

  9. Application to non-destructive assay of 2nd layer tail cylinder at Rokkasho Enrichment plant

    International Atomic Energy Agency (IAEA) safeguards criteria 93+2 requirement stipulates that depleted uranium under the single C/S (Metal or Camera) is re-verified with 10% coverage (β=0.9) once a year, normally during physical inventory verification. In order to maintain the continuity of knowledge, the entire depleted uranium cylinders transferred from the processing area are sealed by inspectorates (the state and the IAEA) after sufficient verification with 50% coverage (β=0.5). At Rokkasho Enrichment plant, the depleted uranium cylinder (0.2∼0.3% enrichment of tail cylinder centrifuged by cascade) separated at the processing area is stored in the cylinder storage. The 2nd layer tail cylinder pile-up has been adopted for efficient-use of the storage; one block is comprised of four cylinders on the lower, three on the upper. The capacity of the specific cylinder crane is limited to as low as height of the upper cylinder. Current lifter with germanium detector is applied to the lower cylinder. However, it is highly possible that inspectorate selects random for the upper tail cylinder at the physical inventory verification. Therefore, at the verification, the operators corporate to lift down the 2nd layer tail cylinder to ground floor so that inspectorate is able to verify it. The Nuclear Material Control Center (NMCC) has designed and manufactured the specific detector lifter capable of the 2nd layer measurement and the potable detector's collimator. Afterwards, we conducted a site test in the plant and inspection efficiency and reduced operator's burden. (author)

  10. PREFACE: 2nd International Conference on Innovative Materials, Structures and Technologies

    Ručevskis, Sandris

    2015-11-01

    The 2nd International Conference on Innovative Materials, Structures and Technologies (IMST 2015) took place in Riga, Latvia from 30th September - 2nd October, 2015. The first event of the conference series, dedicated to the 150th anniversary of the Faculty of Civil Engineering of Riga Technical University, was held in 2013. Following the established tradition, the aim of the conference was to promote and discuss the latest results of industrial and academic research carried out in the following engineering fields: analysis and design of advanced structures and buildings; innovative, ecological and energy efficient building materials; maintenance, inspection and monitoring methods; construction technologies; structural management; sustainable and safe transport infrastructure; and geomatics and geotechnics. The conference provided an excellent opportunity for leading researchers, representatives of the industrial community, engineers, managers and students to share the latest achievements, discuss recent advances and highlight the current challenges. IMST 2015 attracted over 120 scientists from 24 countries. After rigorous reviewing, over 80 technical papers were accepted for publication in the conference proceedings. On behalf of the organizing committee I would like to thank all the speakers, authors, session chairs and reviewers for their efficient and timely effort. The 2nd International Conference on Innovative Materials, Structures and Technologies was organized by the Faculty of Civil Engineering of Riga Technical University with the support of the Latvia State Research Programme under the grant agreement "INNOVATIVE MATERIALS AND SMART TECHNOLOGIES FOR ENVIRONMENTAL SAFETY, IMATEH". I would like to express sincere gratitude to Juris Smirnovs, Dean of the Faculty of Civil Engineering, and Andris Chate, manager of the Latvia State Research Programme. Finally, I would like to thank all those who helped to make this event happen. Special thanks go to Diana

  11. Systems Engineering Approach to Technology Integration for NASA's 2nd Generation Reusable Launch Vehicle

    Thomas, Dale; Smith, Charles; Thomas, Leann; Kittredge, Sheryl

    2002-01-01

    The overall goal of the 2nd Generation RLV Program is to substantially reduce technical and business risks associated with developing a new class of reusable launch vehicles. NASA's specific goals are to improve the safety of a 2nd-generation system by 2 orders of magnitude - equivalent to a crew risk of 1-in-10,000 missions - and decrease the cost tenfold, to approximately $1,000 per pound of payload launched. Architecture definition is being conducted in parallel with the maturating of key technologies specifically identified to improve safety and reliability, while reducing operational costs. An architecture broadly includes an Earth-to-orbit reusable launch vehicle, on-orbit transfer vehicles and upper stages, mission planning, ground and flight operations, and support infrastructure, both on the ground and in orbit. The systems engineering approach ensures that the technologies developed - such as lightweight structures, long-life rocket engines, reliable crew escape, and robust thermal protection systems - will synergistically integrate into the optimum vehicle. To best direct technology development decisions, analytical models are employed to accurately predict the benefits of each technology toward potential space transportation architectures as well as the risks associated with each technology. Rigorous systems analysis provides the foundation for assessing progress toward safety and cost goals. The systems engineering review process factors in comprehensive budget estimates, detailed project schedules, and business and performance plans, against the goals of safety, reliability, and cost, in addition to overall technical feasibility. This approach forms the basis for investment decisions in the 2nd Generation RLV Program's risk-reduction activities. Through this process, NASA will continually refine its specialized needs and identify where Defense and commercial requirements overlap those of civil missions.

  12. The 2nd to 4th Digit Length Difference and Ratio as Predictors of Hyperandrogenism and Metabolic Syndrome in Females

    Pınar Yıldız1; Mustafa Yıldız; Ali Cihat Yıldırım3; et al, ...

    2015-01-01

    Objective: In this study we evaluated the usefulness of 2nd to 4th (2nd:4th) digit length difference and ratio in determining hyperandrogenism in females and the relationship with metabolic syndrome. Methods: We designed a cross-sectional clinical study and examined 150 females who visited our clinic; 137 completed the study. We measured blood pressure and anthropometric values. Biochemical parameters associated with metabolic syndrome were also measured. Results: The mean age of our p...

  13. Future Control and Automation : Proceedings of the 2nd International Conference on Future Control and Automation

    2012-01-01

    This volume Future Control and Automation- Volume 2 includes best papers from 2012 2nd International Conference on Future Control and Automation (ICFCA 2012) held on July 1-2, 2012, Changsha, China. Future control and automation is the use of control systems and information technologies to reduce the need for human work in the production of goods and services. This volume can be divided into six sessions on the basis of the classification of manuscripts considered, which is listed as follows: Mathematical Modeling, Analysis and Computation, Control Engineering, Reliable Networks Design, Vehicular Communications and Networking, Automation and Mechatronics.

  14. [Infected chorionic hematoma as a cause of infection in the 2nd trimester].

    Weigel, M; Friese, K; Schmitt, W; Strittmatter, H J; Melchert, F

    1992-12-01

    Superinfected subchorionic haematomas are a rare septic focus in the 2nd trimenon. Symptoms being unspecific, the diagnosis has to be made by exclusion, in most cases. As the changes of a successful treatment of the manifest infection is poor, antibiotic prophylaxis as well as close laboratory controls and early antibiotic therapy should be discussed after sonographic diagnosis of an intrauterine haematoma. Two of our three patients reported on having suffered a miscarriage; only one pregnancy could be maintained after spontaneous depletion of the infected haemorrhage. PMID:1490559

  15. 2nd ISPRA nuclear electronics symposium, Stresa, Italy May 20-23, 1975

    Two round tables were annexed to the 2nd Ispra Nuclear Electronics Symposium. The first one was concerned with software support for the implementation of microprocessors, MOS and bipolar microporcessors, environmental data systems, and the use of microprocessors and minicomputers in nuclear, biomedical and environmental fields. Nuclear electronics future, and its diversification, gravitational waves and electronics, the environmental measurements of air and water quality were discussed during the second round table, and relevant feelings brought out during the discussion on the extension of nuclear electronics techniques to other fields

  16. 1st and 2nd Trimester Headsize in Fetuses with Congenital Heart Disease: A Cohort Study

    Lauridsen, Mette Høj; Petersen, Olav Bjørn; Vestergaard, Else Marie;

    2014-01-01

    Background: Congenital heart disease (CHD) is associated with neuro-developmental disorders. The influence of CHD on the brain may be present in the fetus. We hypothesize that fetal cerebral growth is impaired as early as 2nd trimester. Aim: To investigate if fetal cerebral growth is associated...... and screening for fetal malformations is carried out. Our cohort includes all fetuses in Western Denmark (2.9 million inhabitants) screened in between January 1st 2012 and December 31st 2013, diagnosed with any structural, non-syndromic congenital heart disease either during pregnancy or up to 6...

  17. Boosting biogas yield of anaerobic digesters by utilizing concentrated molasses from 2nd generation bioethanol plant

    Shiplu Sarker, Henrik Bjarne Møller

    2013-01-01

    Concentrated molasses (C5 molasses) from 2nd generation bioethanol plant has been investigated for enhancing productivity of manure based digesters. A batch study at mesophilic condition (35±1C) showed the maximum methane yield from molasses as 286 LCH4/kgVS which was approximately 63% of the calculated theoretical yield. In addition to the batch study, co-digestion of molasses with cattle manure in a semi-continuously stirred reactor at thermophilic temperature (50±1°C) was also performed wi...

  18. Effects of Thermal Cycling on Control and Irradiated EPC 2nd Generation GaN FETs

    Patterson, Richard L.; Scheick, Leif; Lauenstein, Jean-Marie; Casey, Megan; Hammoud, Ahmad

    2013-01-01

    The power systems for use in NASA space missions must work reliably under harsh conditions including radiation, thermal cycling, and exposure to extreme temperatures. Gallium nitride semiconductors show great promise, but information pertaining to their performance is scarce. Gallium nitride N-channel enhancement-mode field effect transistors made by EPC Corporation in a 2nd generation of manufacturing were exposed to radiation followed by long-term thermal cycling in order to address their reliability for use in space missions. Results of the experimental work are presented and discussed.

  19. Construction of the 2nd 500kV DC gun at KEK

    The 2nd 500 kV DC photocathode electron gun for a ERL injector was constructed at KEK. The gun has some functions such as a insulated anode electrode for using dark current monitor, a repeller electrode for decreasing backward ions, extreme high vacuum pumps and so on. A high voltage conditioning is just begun from this summer. In addition, a new cathode preparation system has been developed. It can prepare three cathodes simultaneously and storage many cathodes in a good vacuum condition. The detail design was finished and the construction of all in-vacuum components is progressing. (author)

  20. TF insert experiment log book. 2nd Experiment of CS model coil

    The cool down of CS model coil and TF insert was started on August 20, 2001. It took almost one month and immediately started coil charge since September 17, 2001. The charge test of TF insert and CS model coil was completed on October 19, 2001. In this campaign, total shot numbers were 88 and the size of the data file in the DAS (Data Acquisition System) was about 4 GB. This report is a database that consists of the log list and the log sheets of every shot. This is an experiment logbook for 2nd experiment of CS model coil and TF insert for charge test. (author)

  1. Mapping and industrial IT project to a 2nd semester design-build project

    Nyborg, Mads; Høgh, Stig

    2010-01-01

    CDIO means bringing the engineer's daily life and working practice into the educational system. In our opinion this is best done by selecting an appropriate project from industry. In this paper we describe how we have mapped an industrial IT project to a 2nd semester design-build project in the Diploma IT program at the Technical University of Denmark. The system in question is a weighing system operating in a LAN environment. The system is used in the medical industry for producing tablets. ...

  2. The 2nd International Association of Neurorestoratology Annual Conference(IANAC)Summary

    Lin CHEN; Da-Qian HUANG; Di CHEN; Hong-Yun HUANG

    2009-01-01

    The 2nd International Association of Neurorestoratology Annual Conference(IANAC)was successfully held in Beijing, China,from April 24 to 26,2009.More than 200 representatives from 30 countries and regions attended the meeting and carried out extensive academic communications and reached important consensus on many issues in neuroregeneration,neural structural repair,neural replacement,neuroprotection,neuromodulation,neurorehabilitation,neuroplasticity and other areas in the field of neurorestoratology.The general assembly adopted"Beijing Declaration of International Association of Neurorestoratology"(Beijing Declaration)that was proposed by 32 scientists from 18 countries.

  3. 2nd International Conference on Multiscale Computational Methods for Solids and Fluids

    2016-01-01

    This volume contains the best papers presented at the 2nd ECCOMAS International Conference on Multiscale Computations for Solids and Fluids, held June 10-12, 2015. Topics dealt with include multiscale strategy for efficient development of scientific software for large-scale computations, coupled probability-nonlinear-mechanics problems and solution methods, and modern mathematical and computational setting for multi-phase flows and fluid-structure interaction. The papers consist of contributions by six experts who taught short courses prior to the conference, along with several selected articles from other participants dealing with complementary issues, covering both solid mechanics and applied mathematics. .

  4. Performance and validation of COMPUCEA 2nd generation for uranium measurements in physical inventory verification

    A new instrumental version of COMPUCEA has been developed with the aim to provide a simplified and more practical instrumentation for in-field use. The main design goals were to eliminate the radioactive sources and the liquid nitrogen-cooled Ge detectors used in the 1st generation of COMPUCEA. This paper describes the major technical features of the 2nd generation of equipment together with typical performance data. The performance tests carried out during first in-field measurements in the course of physical inventory verification campaigns represent an important step in the validation of this new instrument. (author)

  5. The ratio of 2nd to 4th digit length: a new predictor of disease predisposition?

    Manning, J T; Bundred, P E

    2000-05-01

    The ratio between the length of the 2nd and 4th digits is: (a) fixed in utero; (b) lower in men than in women; (c) negatively related to testosterone and sperm counts; and (d) positively related to oestrogen concentrations. Prenatal levels of testosterone and oestrogen have been implicated in infertility, autism, dyslexia, migraine, stammering, immune dysfunction, myocardial infarction and breast cancer. We suggest that 2D:4D ratio is predictive of these diseases and may be used in diagnosis, prognosis and in early life-style interventions which may delay the onset of disease or facilitate its early detection. PMID:10859702

  6. Advanced Electron Beam Ion Sources (EBIS) for 2-nd generation carbon radiotherapy facilities

    In this work we analyze how advanced Electron Beam Ion Sources (EBIS) can facilitate the progress of carbon therapy facilities. We will demonstrate that advanced ion sources enable operation of 2-nd generation ion beam therapy (IBT) accelerators. These new accelerator concepts with designs dedicated to IBT provide beams better suited for therapy and, are more cost efficient than contemporary IBT facilities. We will give a sort overview of the existing new IBT concepts and focus on those where ion source technology is the limiting factor. We will analyse whether this limitation can be overcome in the near future thanks to ongoing EBIS development

  7. Advanced Electron Beam Ion Sources (EBIS) for 2-nd generation carbon radiotherapy facilities

    Shornikov, A.; Wenander, F.

    2016-04-01

    In this work we analyze how advanced Electron Beam Ion Sources (EBIS) can facilitate the progress of carbon therapy facilities. We will demonstrate that advanced ion sources enable operation of 2-nd generation ion beam therapy (IBT) accelerators. These new accelerator concepts with designs dedicated to IBT provide beams better suited for therapy and, are more cost efficient than contemporary IBT facilities. We will give a sort overview of the existing new IBT concepts and focus on those where ion source technology is the limiting factor. We will analyse whether this limitation can be overcome in the near future thanks to ongoing EBIS development.

  8. DRS // CUMULUS Oslo 2013. The 2nd International Conference for Design Education Researchers

    Liv Merete Nielsen

    2013-01-01

    14-17 May 2013, Oslo, NorwayWe have received more than 200 full papers for the 2nd International Conference for Design Education Researchers in Oslo.This international conference is a springboard for sharing ideas and concepts about contemporary design education research. Contributors are invited to submit research that deals with different facets of contemporary approaches to design education research. All papers will be double-blind peer-reviewed. This conference is open to research in any ...

  9. Collection of documents in the 2nd information exchange meeting on radioactive waste disposal research network

    The 2nd meeting on 'Radioactive Waste Disposal Research Network' was held at the Nagoya University Museum on March 30, 2007. The 'Radioactive Waste Disposal Research Network' was established in Interorganization Atomic Energy Research Program under academic collaborative agreement between Japan Atomic Energy Agency and the University of Tokyo. The objective is to develop both research infrastructures and human expertise in Japan to an adequate performance level, thereby contributing to the development of the fundamental research in the field of radioactive waste disposal. This material is a collection of presentations and discussions during the information exchange meeting. (author)

  10. PREFACE: 2nd International Meeting for Researchers in Materials and Plasma Technology

    Niño, Ely Dannier V.

    2013-11-01

    These proceedings present the written contributions of the participants of the 2nd International Meeting for Researchers in Materials and Plasma Technology, 2nd IMRMPT, which was held from February 27 to March 2, 2013 at the Pontificia Bolivariana Bucaramanga-UPB and Santander and Industrial - UIS Universities, Bucaramanga, Colombia, organized by research groups from GINTEP-UPB, FITEK-UIS. The IMRMPT, was the second version of biennial meetings that began in 2011. The three-day scientific program of the 2nd IMRMPT consisted in 14 Magisterial Conferences, 42 Oral Presentations and 48 Poster Presentations, with the participation of undergraduate and graduate students, professors, researchers and entrepreneurs from Colombia, Russia, France, Venezuela, Brazil, Uruguay, Argentina, Peru, Mexico, United States, among others. Moreover, the objective of IMRMPT was to bring together national and international researchers in order to establish scientific cooperation in the field of materials science and plasma technology; introduce new techniques of surface treatment of materials to improve properties of metals in terms of the deterioration due to corrosion, hydrogen embrittlement, abrasion, hardness, among others; and establish cooperation agreements between universities and industry. The topics covered in the 2nd IMRMPT include New Materials, Surface Physics, Laser and Hybrid Processes, Characterization of Materials, Thin Films and Nanomaterials, Surface Hardening Processes, Wear and Corrosion / Oxidation, Modeling, Simulation and Diagnostics, Plasma Applications and Technologies, Biomedical Coatings and Surface Treatments, Non Destructive Evaluation and Online Process Control, Surface Modification (Ion Implantation, Ion Nitriding, PVD, CVD). The editors hope that those interested in the are of materials science and plasma technology, enjoy the reading that reflect a wide range of topics. It is a pleasure to thank the sponsors and all the participants and contributors for

  11. Proceedings 2nd Workshop on Formal Methods in the Development of Software

    Andrés, César; Llana, Luis

    2012-01-01

    This volume contains the proceedings of the 2nd WorkShop on Formal Methods in the Development of Software (WS-FMDS 2012). The workshop was held in Paris, France on August 30th, 2012 as a satellite event to the 18th International Symposium on Formal Methods (FM-2012). The aim of WS-FMDS 2012 is to provide a forum for researchers who are interested in the application of formal methods on systems which are being developing with a software methodology. In particular, this workshop is intended to ...

  12. A ZeroDimensional Model of a 2nd Generation Planar SOFC Using Calibrated Parameters

    Brian Elmegaard

    2006-12-01

    Full Text Available This paper presents a zero-dimensional mathematical model of a planar 2nd generation coflow SOFC developed for simulation of power systems. The model accounts for the electrochemical oxidation of hydrogen as well as the methane reforming reaction and the water-gas shift reaction. An important part of the paper is the electrochemical sub-model, where experimental data was used to calibrate specific parameters. The SOFC model was implemented in the DNA simulation software which is designed for energy system simulation. The result is an accurate and flexible tool suitable for simulation of many different SOFC-based power systems.

  13. Mesocosm soil ecological risk assessment tool for GMO 2nd tier studies

    D'Annibale, Alessandra; Maraldo, Kristine; Larsen, Thomas;

    effects in 2nd tier caged experimental systems, cf. the new GMO ERA guidance: EFSA Journal 2010; 8(11):1879. We propose to perform a trophic structure analysis, TSA, and include the trophic structure as an ecological endpoint to gain more direct insight into the change in interactions between species, i...... control. After 5 and 11 weeks, data on populations, plants and soil organic matter decomposition were evaluated. Natural abundances of stable isotopes, 13C and 15N, of animals, soil, plants and added organic matter (crushed maize leaves) were used to describe the soil food web structure....

  14. [Model and enlightenment from rescue of August 2nd Kunshan explosion casualty].

    Tan, Q; Qiu, H B; Sun, B W; Shen, Y M; Nie, L J; Zhang, H W

    2016-01-01

    On August 2nd, 2014, a massive dust explosion occurred in a factory of Kunshan, resulting in a mass casualty involving 185 burn patients. They were transported to 20 medical institutions in Jiangsu province and Shanghai. More than one thousand of medical personnel of our country participated in this emergency rescue, and satisfactory results were achieved. In this paper, the characteristics of this accident were analyzed, the positive effects of interdisciplinary cooperation were affirmed, and the contingency plan, rescue process and pattern, and reserve, organization and management of talents during this rescue process were reviewed retrospectively. PMID:27426066

  15. Future Control and Automation : Proceedings of the 2nd International Conference on Future Control and Automation

    2012-01-01

    This volume Future Control and Automation- Volume 1 includes best papers selected from 2012 2nd International Conference on Future Control and Automation (ICFCA 2012) held on July 1-2, 2012, Changsha, China. Future control and automation is the use of control systems and information technologies to reduce the need for human work in the production of goods and services. This volume can be divided into five sessions on the basis of the classification of manuscripts considered, which is listed as follows: Identification and Control, Navigation, Guidance and Sensor, Simulation Technology, Future Telecommunications and Control

  16. CTV delineation for rectal cancer treatment: ambiguities defined by a national review project

    Joye, Ines; Van Herck, Hans; Slagmolen, Pieter; Defraene, Gilles; Hortobagyi, Eszter; Maes, Frederik; Haustermans, Karin

    2014-01-01

    Joye I., Van Herck H., Slagmolen P., Defraene G., Hortobagyi E., Maes F., Haustermans K., ''CTV delineation for rectal cancer treatment: ambiguities defined by a national review project'', Radiotherapy and oncology, vol. 111 suppl. 1, pp. S195, April 2014 (European Society for Radiotherapy & Oncology - ESTRO 33, April 4-8, 2014, Vienna, Austria).

  17. Early Proctoscopy is a Surrogate Endpoint of Late Rectal Toxicity in Prostate Cancer Treated With Radiotherapy

    Ippolito, Edy; Massaccesi, Mariangela; Digesu, Cinzia; Deodato, Francesco [Radiotherapy Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Universita Cattolica del S. Cuore, Campobasso (Italy); Macchia, Gabriella, E-mail: gmacchia@rm.unicatt.it [Radiotherapy Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Universita Cattolica del S. Cuore, Campobasso (Italy); Pirozzi, Giuseppe Antonio [Endoscopy Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Universita Cattolica del S. Cuore, Campobasso (Italy); Cilla, Savino [Medical Physics Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Universita Cattolica del S. Cuore, Campobasso (Italy); Cuscuna, Daniele; Di Lallo, Alessandra [Urology Unit, General Hospital A. Cardarelli, Campobasso (Italy); Mattiucci, Gian Carlo; Mantini, Giovanna [Department of Radiotherapy, Policlinico Universitario Agostino Gemelli, Universita Cattolica del S. Cuore, Rome (Italy); Pacelli, Fabio [Surgery Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Universita Cattolica del S. Cuore, Campobasso (Italy); Valentini, Vincenzo; Cellini, Numa [Department of Radiotherapy, Policlinico Universitario Agostino Gemelli, Universita Cattolica del S. Cuore, Rome (Italy); Ingrosso, Marcello [Endoscopy Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Universita Cattolica del S. Cuore, Campobasso (Italy); Morganti, Alessio Giuseppe [Radiotherapy Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Universita Cattolica del S. Cuore, Campobasso (Italy); Department of Radiotherapy, Policlinico Universitario Agostino Gemelli, Universita Cattolica del S. Cuore, Rome (Italy)

    2012-06-01

    Purpose: To predict the grade and incidence of late clinical rectal toxicity through short-term (1 year) mucosal alterations. Methods and Materials: Patients with prostate adenocarcinoma treated with curative or adjuvant radiotherapy underwent proctoscopy a year after the course of radiotherapy. Mucosal changes were classified by the Vienna Rectoscopy Score (VRS). Late toxicity data were analyzed according to the Kaplan-Meier method. Comparison between prognosis groups was performed by log-rank analysis. Results: After a median follow-up time of 45 months (range, 18-99), the 3-year incidence of grade {>=}2 rectal late toxicity according to the criteria of the European Organization for Research and Treatment of Cancer and the Radiation Therapy Oncology Group was 24%, with all patients (24/24; 100%) experiencing rectal bleeding. The occurrence of grade {>=}2 clinical rectal late toxicity was higher in patients with grade {>=}2 (32% vs. 15 %, p = 0.02) or grade {>=}3 VRS telangiectasia (47% vs. 17%, p {<=} 0.01) and an overall VRS score of {>=}2 (31% vs. 16 %, p = 0.04) or {>=}3 (48% vs. 17%, p = 0.01) at the 1-year proctoscopy. Conclusions: Early proctoscopy (1 year) predicts late rectal bleeding and therefore can be used as a surrogate endpoint for late rectal toxicity in studies aimed at reducing this frequent complication.

  18. Early Proctoscopy is a Surrogate Endpoint of Late Rectal Toxicity in Prostate Cancer Treated With Radiotherapy

    Purpose: To predict the grade and incidence of late clinical rectal toxicity through short-term (1 year) mucosal alterations. Methods and Materials: Patients with prostate adenocarcinoma treated with curative or adjuvant radiotherapy underwent proctoscopy a year after the course of radiotherapy. Mucosal changes were classified by the Vienna Rectoscopy Score (VRS). Late toxicity data were analyzed according to the Kaplan-Meier method. Comparison between prognosis groups was performed by log-rank analysis. Results: After a median follow-up time of 45 months (range, 18–99), the 3-year incidence of grade ≥2 rectal late toxicity according to the criteria of the European Organization for Research and Treatment of Cancer and the Radiation Therapy Oncology Group was 24%, with all patients (24/24; 100%) experiencing rectal bleeding. The occurrence of grade ≥2 clinical rectal late toxicity was higher in patients with grade ≥2 (32% vs. 15 %, p = 0.02) or grade ≥3 VRS telangiectasia (47% vs. 17%, p ≤ 0.01) and an overall VRS score of ≥2 (31% vs. 16 %, p = 0.04) or ≥3 (48% vs. 17%, p = 0.01) at the 1-year proctoscopy. Conclusions: Early proctoscopy (1 year) predicts late rectal bleeding and therefore can be used as a surrogate endpoint for late rectal toxicity in studies aimed at reducing this frequent complication.

  19. Editorial: 2nd Special Issue on behavior change, health, and health disparities.

    Higgins, Stephen T

    2015-11-01

    This Special Issue of Preventive Medicine (PM) is the 2nd that we have organized on behavior change, health, and health disparities. This is a topic of fundamental importance to improving population health in the U.S. and other industrialized countries that are trying to more effectively manage chronic health conditions. There is broad scientific consensus that personal behavior patterns such as cigarette smoking, other substance abuse, and physical inactivity/obesity are among the most important modifiable causes of chronic disease and its adverse impacts on population health. As such behavior change needs to be a key component of improving population health. There is also broad agreement that while these problems extend across socioeconomic strata, they are overrepresented among more economically disadvantaged populations and contribute directly to the growing problem of health disparities. Hence, behavior change represents an essential step in curtailing that unsettling problem as well. In this 2nd Special Issue, we devote considerable space to the current U.S. prescription opioid addiction epidemic, a crisis that was not addressed in the prior Special Issue. We also continue to devote attention to the two largest contributors to preventable disease and premature death, cigarette smoking and physical inactivity/obesity as well as risks of co-occurrence of these unhealthy behavior patterns. Across each of these topics we included contributions from highly accomplished policy makers and scientists to acquaint readers with recent accomplishments as well as remaining knowledge gaps and challenges to effectively managing these important chronic health problems. PMID:26257372

  20. A novel 2nd-order bandpass MFSS filter with miniaturized structure

    C. Y. Fang

    2015-08-01

    Full Text Available In order to effectively obtain a miniaturized structure and good filtering properties, we propose a novel 2nd-order bandpass metamaterial frequency selective surface (MFSS filter which contains two capacitive layers and one inductive layer, where there are multi-loop metallic patches as shunt capacitor C and planar wire grids as series inductor L respectively. Unlike the traditional operation way—the tuned elements used in resonant surface approximately equal to one wavelength in circumference and the structure thickness with a spacing of a quarter wavelength apart, by changing the value of L and C and matching multilayer dielectric to adjust the LC coupling resonance and the resonance impedance respectively, the proposed MFSS filter can achieves a miniatured structure with ideal bandpass properties. Measurement results of the fabricated prototype of the bandpass filter (BPF indicate that the dimension of the tuned element on resonant surface is approximately 0.025 wavelength, i.e., 0.025λ. At the same time, the filter has the stable center frequency of f0 = 1.53GHz and the transmittance of T ⩾ 96.3% and high Q-value for the TE/TM wave polarization at various incidence angles. The novel 2nd-order bandpass MFSS filter with miniaturized structure not only can decrease structure dimension, but also has a wide range of applications to microwave and infrared band.

  1. Proceedings of the 2nd technical meeting on high temperature gas-cooled reactors

    From the point of view for establishing and upgrading the technology basis of HTGRs, the 2nd Technical Meeting on High Temperature Gas-cooled Reactors (HTGRs) was held on March 11 and 12, 1992, in Tokai Research Establishment in order to review the present status and the results of Research and Development (R and D) of HTGRs, to discuss on the items of R and D which should be promoted more positively in the future and then, to help in determining the strategy of development of high temperature engineering and examination in JAERI. At the 2nd Technical Meeting, which followed the 1st Technical Meeting held in February 1990 in Tokai Research Establishment, expectations to the High Temperature Engineering Test Reactor (HTTR), possible contributions of the HTGRs to the preservation of the global environment and the prospect of HTGRs were especially discussed, focusing on the R and D of Safety, high temperature components and process heat utilization by the experts from JAERI as well as universities, national institutes, industries and so on. This proceedings summarizes the papers presented in the oral sessions and materials exhibited in the poster session at the meeting and will be variable as key materials for promoting the R and D on HTGRs from now on. (author)

  2. Efficacy and Safety of rAAV2-ND4 Treatment for Leber's Hereditary Optic Neuropathy.

    Wan, Xing; Pei, Han; Zhao, Min-Jian; Yang, Shuo; Hu, Wei-Kun; He, Heng; Ma, Si-Qi; Zhang, Ge; Dong, Xiao-Yan; Chen, Chen; Wang, Dao-Wen; Li, Bin

    2016-01-01

    Leber's hereditary optic neuropathy (LHON) is a mitochondrially inherited disease leading to blindness. A mitochondrial DNA point mutation at the 11778 nucleotide site of the NADH dehydrogenase subunit 4 (ND4) gene is the most common cause. The aim of this study was to evaluate the efficacy and safety of a recombinant adeno-associated virus 2 (AAV2) carrying ND4 (rAAV2-ND4) in LHON patients carrying the G11778A mutation. Nine patients were administered rAAV2-ND4 by intravitreal injection to one eye and then followed for 9 months. Ophthalmologic examinations of visual acuity, visual field, and optical coherence tomography were performed. Physical examinations included routine blood and urine. The visual acuity of the injected eyes of six patients improved by at least 0.3 log MAR after 9 months of follow-up. In these six patients, the visual field was enlarged but the retinal nerve fibre layer remained relatively stable. No other outcome measure was significantly changed. None of the nine patients had local or systemic adverse events related to the vector during the 9-month follow-up period. These findings support the feasible use of gene therapy for LHON. PMID:26892229

  3. Kinetics and dosimetry of iodine-131-labelled antibody fragments after local administration in patients with rectal cancer

    In 11 patients with rectal cancer, a mixture of F(ab')2 fragments of anti-carcinomembryonic antigen and anti-CA 19.9 labelled with a diagnostic dose of iodine-131 (3-10 MBq) was administered submucosally around the tumour. In this study, the local kinetics in and the dose to the rectal wall, the whole body kinetics and the effective dose equivalent are presented. Initially, about 50% of the plasma activity was due to free 131I. After 4 h, the plasma activity was almost completely protein bound (86%). Maximum plasma activity was observed after the 2nd day. In the first 24 h, 14% of the injected dose was excreted in the urine and within 4 days about half of the administered activity. The absorbed radiation dose to the rectal wall was estimated to be 0.2 Gy/MBq. The dose to the bone marrow was 0.2 mGy/MBq or 0.4 mGy/MBq, assuming a homogeneous tracer distribution or equal blood and bone marrow activity concentrations, respectively. The effective dose equivalent is 1.9 mSv/MBq. We conclude that the theoretical advantages of the local administration of 131I-labelled antibodies for diagnostic purposes in patients with rectal cancer are not limited by our dosimetric data. Nevertheless, we advocate the use of other radiolabels with more appropriate imaging qualities and probably a lower radiation burden. (orig./MG)

  4. Scoping analysis of the Advanced Test Reactor using SN2ND

    Wolters, E.; Smith, M. (NE NEAMS PROGRAM); ( SC)

    2012-07-26

    A detailed set of calculations was carried out for the Advanced Test Reactor (ATR) using the SN2ND solver of the UNIC code which is part of the SHARP multi-physics code being developed under the Nuclear Energy Advanced Modeling and Simulation (NEAMS) program in DOE-NE. The primary motivation of this work is to assess whether high fidelity deterministic transport codes can tackle coupled dynamics simulations of the ATR. The successful use of such codes in a coupled dynamics simulation can impact what experiments are performed and what power levels are permitted during those experiments at the ATR. The advantages of the SN2ND solver over comparable neutronics tools are its superior parallel performance and demonstrated accuracy on large scale homogeneous and heterogeneous reactor geometries. However, it should be noted that virtually no effort from this project was spent constructing a proper cross section generation methodology for the ATR usable in the SN2ND solver. While attempts were made to use cross section data derived from SCALE, the minimal number of compositional cross section sets were generated to be consistent with the reference Monte Carlo input specification. The accuracy of any deterministic transport solver is impacted by such an approach and clearly it causes substantial errors in this work. The reasoning behind this decision is justified given the overall funding dedicated to the task (two months) and the real focus of the work: can modern deterministic tools actually treat complex facilities like the ATR with heterogeneous geometry modeling. SN2ND has been demonstrated to solve problems with upwards of one trillion degrees of freedom which translates to tens of millions of finite elements, hundreds of angles, and hundreds of energy groups, resulting in a very high-fidelity model of the system unachievable by most deterministic transport codes today. A space-angle convergence study was conducted to determine the meshing and angular cubature

  5. Scoping analysis of the Advanced Test Reactor using SN2ND

    A detailed set of calculations was carried out for the Advanced Test Reactor (ATR) using the SN2ND solver of the UNIC code which is part of the SHARP multi-physics code being developed under the Nuclear Energy Advanced Modeling and Simulation (NEAMS) program in DOE-NE. The primary motivation of this work is to assess whether high fidelity deterministic transport codes can tackle coupled dynamics simulations of the ATR. The successful use of such codes in a coupled dynamics simulation can impact what experiments are performed and what power levels are permitted during those experiments at the ATR. The advantages of the SN2ND solver over comparable neutronics tools are its superior parallel performance and demonstrated accuracy on large scale homogeneous and heterogeneous reactor geometries. However, it should be noted that virtually no effort from this project was spent constructing a proper cross section generation methodology for the ATR usable in the SN2ND solver. While attempts were made to use cross section data derived from SCALE, the minimal number of compositional cross section sets were generated to be consistent with the reference Monte Carlo input specification. The accuracy of any deterministic transport solver is impacted by such an approach and clearly it causes substantial errors in this work. The reasoning behind this decision is justified given the overall funding dedicated to the task (two months) and the real focus of the work: can modern deterministic tools actually treat complex facilities like the ATR with heterogeneous geometry modeling. SN2ND has been demonstrated to solve problems with upwards of one trillion degrees of freedom which translates to tens of millions of finite elements, hundreds of angles, and hundreds of energy groups, resulting in a very high-fidelity model of the system unachievable by most deterministic transport codes today. A space-angle convergence study was conducted to determine the meshing and angular cubature

  6. Sleeping position and rectal temperature.

    Petersen, S A; Anderson, E.S.; Lodemore, M; Rawson, D.; Wailoo, M P

    1991-01-01

    The effects of sleeping position upon body temperature were assessed by continuous monitoring of rectal temperature in 137 babies sleeping at home under conditions chosen by their parents. There were three groups of subjects: (1) normal babies aged 12-22 weeks whose temperature rhythms were developed, (2) normal babies aged 6-12 weeks who were developing their night time temperature rhythms, and (3) babies the night after diphtheria, pertussis, and tetanus immunisation, whose temperature rhyt...

  7. Towards the European strategy for particle physics the Briefing Book

    Åkesson, T; Allanach, Benjamin C; Bertolucci, S; Blondel, A; Butterworth, J; Cavalli-Sforza, M; Cervera-Villanueva, Anselmo; Davidson, S; De Naurois, Mathieu; Desch, K; Egede, U; Glover, N; Heuer, R D; Huber, P; Höcker, A; Jungmann, K; Landua, Rolf; Le Goff, J M; Linde, Frank L; Lombardi, A; Mangano, Michelangelo L; Mezzetto, M; Onderwater, G; Palanque-Delabrouille, Nathalie; Peach, Kenneth J; Polosa, A; Rondio, E; Webber, Bryan R; Weiglein, G; Womersley, J; Wurr, K

    2007-01-01

    This document was prepared as part of the briefing material for the Workshop of the CERN Council Strategy Group, held in DESY Zeuthen from 2nd to 6th May 2006. It gives an overview of the physics issues and of the technological challenges that will shape the future of the field, and incorporates material presented and discussed during the Symposium on the European Strategy for Particle Physics, held in Orsay from 30th January to 2nd February 2006, reflecting the various opinions of the European community as recorded in written submissions to the Strategy Group and in the discussions at the Symposium.

  8. [Rectal resection with colo-anal anastomosis for ergotamine-induced rectal stenosis].

    Panis, Y; Valleur, P; Kleinmann, P; Willems, G; Hautefeuille, P

    1990-01-01

    Anorectal ulcers due to ergotamine suppositories are extremely rare. We report the first case of rectal stenosis following regular abuse of ergotamine suppositories which required rectal resection and coloanal anastomosis, despite stopping the intoxication 1 year previously. The rectal eversion during the perineal procedure allowed a low anastomosis to be performed, on the dentate line. One year later, the functional result was considered to be good, demonstrating the place of coloanal anastomosis in benign rectal pathology. PMID:2100123

  9. Bioavailability of rectally administered carbamazepine mixture.

    Neuvonen, P J; Tokola, O.

    1987-01-01

    The relative bioavailability of carbamazepine mixture was studied after oral and rectal administration to healthy subjects. The absorption was significantly slower after the rectal than after the oral route but the total bioavailability was similar provided the mixture was not defaecated within 2 h of administration. We conclude that carbamazepine can be administered rectally, e.g. to postoperative patients in doses corresponding with oral doses.

  10. Advances in Multidisciplinary Treatment of Rectal Cancer

    Zhao, Changlin; Hongqin SUN; Yang, Yang

    2009-01-01

    To summarize the advances in the multidisciplinary treatment of rectal cancer and to analyze the existing problems and development prospects. The full text database retrieval system of MEDLINE and the periodicals of CHKD were searched. The words “rectal cancer, diagnosis, surgery, chemotherapy, radiotherapy, targeted therapy, analysis” were used as key words for retrieval of literature concerning the values and clinical significance of rectal cancer multidisciplinary treatment from January, 2...

  11. Chemoradiotherapy response in recurrent rectal cancer

    The efficacy of response to preoperative chemoradiotherapy (CRT) in recurrent versus primary rectal cancer has not been investigated. We compared radiological downsizing between primary and recurrent rectal cancers following CRT and determined the optimal size reduction threshold for response validated by survival outcomes. The proportional change in tumor length for primary and recurrent rectal cancers following CRT was compared using the independent sample t-test. Overall survival (OS) was calculated using the Kaplan–Meier product limit method and differences between survival for tumor size reduction thresholds of 30% (response evaluation criteria in solid tumors [RECIST]), 40%, and 50% after CRT in primary and recurrent rectal cancer groups. A total of 385 patients undergoing CRT were analyzed, 99 with recurrent rectal cancer and 286 with primary rectal cancer. The mean proportional reduction in maximum craniocaudal length was significantly higher for primary rectal tumors (33%) compared with recurrent rectal cancer (11%) (P < 0.01). There was no difference in OS for either primary or recurrent rectal cancer when ≤30% or ≤40% definitions were used. However, for both primary and recurrent tumors, significant differences in median 3-year OS were observed when a RECIST cut-off of 50% was used. OS was 99% versus 77% in primary and 100% versus 42% in recurrent rectal cancer (P = 0.002 and P = 0.03, respectively). Only patients that demonstrated >50% size reduction showed a survival benefit. Recurrent rectal cancer appears radioresistant compared with primary tumors for tumor size after CRT. Further investigation into improving/intensifying chemotherapy and radiotherapy for locally recurrent rectal cancer is justified

  12. Rectal function following prostate brachytherapy

    Purpose: Quality of life following therapeutic intervention for carcinoma of the prostate gland has not been well documented. In particular, a paucity of data has been published regarding bowel function following prostate brachytherapy. This study evaluated late bowel function in 209 consecutive prostate brachytherapy patients via a one-time questionnaire administered 16-55 months postimplant. Materials and Methods: Two hundred nineteen consecutive patients underwent permanent prostate brachytherapy from April 1995 through February 1998 using either 125I or 103Pd for clinical T1c-T3a carcinoma of the prostate gland. Of the 219 patients, 7 had expired. Of the remaining 212 patients (median follow-up, 28 months), each patient was mailed a self-administered questionnaire (10 questions) with a prestamped return envelope; 209 (98.6%) surveys were returned. Clinical parameters evaluated for bowel dysfunction included patient age, diabetes, hypertension, history of tobacco consumption, clinical T-stage, elapsed time since implant, and prostate ultrasound volume. Treatment parameters included utilization of neoadjuvant hormonal manipulation, utilization of moderate dose external beam radiation therapy prior to implantation, choice of isotope (125I vs. 103Pd), rectal dose (average, median and maximum doses), total implanted seed strength, values of the minimum dose received by 90% of the prostate gland (D90), and the percent prostate volume receiving 100%, 150%, and 200% of the prescribed minimum peripheral dose (V100, V150 and V200, respectively). Because detailed baseline bowel function was not available for these patients, a cross-sectional survey was performed in which 30 newly diagnosed prostate cancer patients of comparable demographics served as controls. Results: The total rectal function scores for the brachytherapy and control patients were 4.3 and 1.6, respectively, out of a total 27 points (p 103Pd resulted in lower radiation doses to the rectum, the choice of

  13. Access to Vocational Training in Three Sectors of the European Economy. Comparative Analysis. 2nd Edition. CEDEFOP Panorama.

    Lassibille, Gerard; Paul, Jean-Jacques

    This report presents findings of a study of the theoretical and practical methods of access to continuing vocational training. It summarizes six reports that compare the following: the construction sector in Spain, France, Italy, and Luxembourg; the banking, insurance, commerce, and administration sectors in Germany, Ireland, the Netherlands, and…

  14. The Planar Optics Phase Sensor: a study for the VLTI 2nd Generation Fringe Tracker

    Blind, Nicolas; Absil, Olivier; Alamir, Mazen; Berger, Jean-Philippe; Defrère, Denis; Feautrier, Philippe; Hénault, Franois; Jocou, Laurent; Kern, Pierre; Laurent, Thomas; Malbet, Fabien; Mourard, Denis; Rousselet-Perrault, Karine; Sarlette, Alain; Surdej, Jean; Tarmoul, Nassima; Tatulli, Eric; Vincent, Lionel; 10.1117/12.857114

    2010-01-01

    In a few years, the second generation instruments of the Very Large Telescope Interferometer (VLTI) will routinely provide observations with 4 to 6 telescopes simultaneously. To reach their ultimate performance, they will need a fringe sensor capable to measure in real time the randomly varying optical paths differences. A collaboration between LAOG (PI institute), IAGL, OCA and GIPSA-Lab has proposed the Planar Optics Phase Sensor concept to ESO for the 2nd Generation Fringe Tracker. This concept is based on the integrated optics technologies, enabling the conception of extremely compact interferometric instruments naturally providing single-mode spatial filtering. It allows operations with 4 and 6 telescopes by measuring the fringes position thanks to a spectrally dispersed ABCD method. We present here the main analysis which led to the current concept as well as the expected on-sky performance and the proposed design.

  15. Tetragonal ZrO2:Nd3+ nanosphere: Combustion synthesis, luminescence and photoacoustic spectroscopy

    Gupta, Santosh K.; Chandrasekhar, D.; Kadam, R. M.

    2015-12-01

    Nanocrystalline ZrO2:Nd3+ was synthesised using gel-combustion method and characterized systematically using X-ray diffraction (XRD) and transmission electron microscopy (TEM). Through this route we can stabilize metastable tetragonal phase at 500 °C through addition of 1 mol % Nd3+ which is technologically more important. Optical characterization of the sample was done using photoluminescence (PL) and photoacoustic spectroscopy (PAS). PL studies shows an intense and optimum stimulated emission cross section of 1065 nm peak corresponding to 4F3/2 → 4I11/2 which and thus it can be a probable laser material. PAS is used to investigate electronic absorption of Nd3 in zirconia. Various covalency parameters like nephelauxetic ratio (β), covalency factor (b1/2) and Sinha parameter (δ) were evaluated for pure oxide powder and as well as for Nd3+ doped zirconia.

  16. Book Review: The Communicating Leader: The key to strategic alignment (2nd Ed

    X. C. Birkenbach

    2003-10-01

    Full Text Available Title: The Communicating Leader: The key to strategic alignment (2nd Ed Author: Gustav Puth Publisher: Van Schaik Publishers Reviewer: XC Birkenbach The aim of the book according to the author, is "meant to be a usable tool, an instrument in the toolbox of the real leader and leadership student". The book is written in conversational style (as intended by the author and the 219 pages of the 10 chapters are logically packaged into three parts. While the main emphasis is naturally on leadership and communication, the coverage includes topics typically encountered in Organisational Behaviour or Management texts, e.g., organizational culture, managing change, motivation, conflict management and strategic management.

  17. 2nd International Conference on Education and Educational Technology (EET 2011)

    Education and Educational Technology

    2012-01-01

    This volume includes extended and revised versions of a set of selected papers from the 2011 2nd International Conference on Education and Educational Technology (EET 2011) held in Chengdu, China, October 1-2, 2011. The mission of EET 2011 Volume 1 is to provide a forum for researchers, educators, engineers, and government officials involved in the general areas of education and educational technology to disseminate their latest research results and exchange views on the future research directions of these fields. 130 related topic papers were selected into this volume. All the papers were reviewed by 2 program committee members and selected by the volume editor Prof. Yuanzhi Wang, from Intelligent Information Technology Application Research Association, Hong Kong. The conference will bring together leading researchers, engineers and scientists in the domain of interest. We hope every participant can have a good opportunity to exchange their research ideas and results and to discuss the state of the art in th...

  18. Proceedings of the 2nd seminar of R and D on advanced ORIENT

    The 2nd Seminar of R and D on advanced ORIENT was held at Ricotte, on November 7th, 2008, Japan Atomic Energy Agency. The first meeting of this seminar was held on Oarai, Ibaraki on May, 2008, and more than fifty participants including related researchers and general public people were attended to this seminar. The second seminar has headed by Nuclear Science and Engineering Directorate, JAEA on Tokai, Ibaraki with 63 participants. Spent nuclear fuel should be recognized not only mass of radioactive elements but also potentially useful materials including platinum metals and rare earth elements. Taking the cooperation with universities related companies and research institutes, into consideration, we aimed at expanding and progressing the basic researches. This report records abstracts and figures submitted from the oral speakers in this seminar. (author)

  19. Preliminary GPS orbit combination results of the IGS 2nd reprocessing campaign

    Choi, Kevin

    2015-04-01

    International GNSS Service (IGS) has contributed to the International Terrestrial Reference Frame by reprocessing historic GPS network data and submitting Terrestrial Reference Frame solutions and Earth Rotation Parameters. For the 2nd reprocessing campaign, Analysis Centers (ACs) used up to 21 years of GPS observation data with daily integrations. IERS2010 conventions are applied to model the physical effects of the Earth. Total eight ACs have participated (7 Global solutions, and 2 Tide Gauge solutions) by reprocessing entire time series in a consistent way using the latest models and methodology. IGS combined daily SINEX TRF and EOP combinations have already been submitted to the IERS for ITRF2013. This presentation mainly focuses on the preliminary quality assessment of the reprocessed AC orbits. Quality of the orbit products are examined by examining the repeatability between daily AC satellite ephemeris. Power spectral analysis shows the background noise characteristics of each AC products, and its periodic behaviors.

  20. Summary of the 2nd workshop on ion beam-applied biology

    Induction of novel plant resources by ion beam-irradiation has been investigated in JAERI. To share the knowledge of the present status of the field, and to find out future plants, 1st Workshop on ion beam-applied biology was held last year titled as ''Development of breeding technique for ion beams''. To further improve the research cooperation and to exchange useful information in the field, researchers inside JAERI and also with researchers outside, such as those from agricultural experiment stations, companies, and Universities met each other at the 2nd workshop on ion beam-applied biology titled as ''Future development of breeding technique for ion beams''. People from RIKEN, Institute of Radiation Breeding, Wakasa wan Energy Research Center, National Institute of Radiological Science also participated in this workshop. The 12 of the presented papers are indexed individually. (J.P.N.)

  1. 2nd Canada-China joint workshop on supercritical-water-cooled reactors (CCSC-2010)

    The 2nd Canada-China Joint Workshop on Supercritical-Water-Cooled Reactors (CCSC-2010) was held in Toronto, Ontario, Canada on April 25-25, 2010. This joint workshop aimed at providing a forum for discussion of advancements and issues, sharing information and technology transfer, and establishing future collaborations on research and developments for supercritical water-cooled reactors (SCWR) between Canadian and Chinese research organizations. Participants were those involved in research and development of SCWR core design, materials, chemistry, corrosion, thermalhydraulics, and safety analysis at organizations in Canada and China. Papers related to the following topics were of interest to the workshop: reactor core and fuel designs; materials, chemistry and corrosion; thermalhydraulics and safety analysis; balance of plant; and other applications.

  2. 2nd International Conference on Electrical Systems, Technology and Information 2015

    Tanoto, Yusak; Lim, Resmana; Santoso, Murtiyanto; Pah, Nemuel

    2016-01-01

    This book includes the original, peer-reviewed research papers from the 2nd International Conference on Electrical Systems, Technology and Information (ICESTI 2015), held in September 2015 at Patra Jasa Resort & Villas Bali, Indonesia. Topics covered include: Mechatronics and Robotics, Circuits and Systems, Power and Energy Systems, Control and Industrial Automation, and Information Theory.    It explores emerging technologies and their application in a broad range of engineering disciplines, including communication technologies and smart grids. It examines hybrid intelligent and knowledge-based control, embedded systems, and machine learning. It also presents emerging research and recent application in green energy system and storage. It discusses the role of electrical engineering in biomedical, industrial and mechanical systems, as well as multimedia systems and applications, computer vision and image and signal processing. The primary objective of this series is to provide references for disseminat...

  3. 2nd International Colloquium on Sports Science, Exercise, Engineering and Technology 2015

    Sulaiman, Norasrudin; Adnan, Rahmat

    2016-01-01

    The proceeding is a collection of research papers presented at the 2nd International Colloquium on Sports Science, Exercise, Engineering and Technology (ICoSSEET2015), a conference dedicated to address the challenges in the areas of sports science, exercise, sports engineering and technology including other areas of sports, thereby presenting a consolidated view to the interested researchers in the aforesaid fields. The goal of this conference was to bring together researchers and practitioners from academia and industry to focus on the scope of the conference and establishing new collaborations in these areas. The topics of interest are in mainly (1) Sports and Exercise Science (2) Sports Engineering and Technology Application (3) Sports Industry and Management.

  4. 2nd Symposium on Fluid-Structure-Sound Interactions and Control

    Liu, Yang; Huang, Lixi; Hodges, Dewey

    2014-01-01

    With rapid economic and industrial development in China, India and elsewhere, fluid-related structural vibration and noise problems are widely encountered in many fields, just as they are in the more developed parts of the world, causing increasingly grievous concerns. Turbulence clearly has a significant impact on many such problems. On the other hand, new opportunities are emerging with the advent of various new technologies, such as signal processing, flow visualization and diagnostics, new functional materials, sensors and actuators, etc. These have revitalized interdisciplinary research activities, and it is in this context that the 2nd symposium on fluid-structure-sound interactions and control (FSSIC) was organized. Held in Hong Kong (May 20-21, 2013) and Macau (May 22-23, 2013), the meeting brought together scientists and engineers working in all related branches from both East and West and provided them with a forum to exchange and share the latest progress, ideas and advances and to chart the fronti...

  5. The New 2nd-Generation SRF R&D Facility at Jefferson Lab: TEDF

    Reece, Charles E.; Reilly, Anthony V.

    2012-09-01

    The US Department of Energy has funded a near-complete renovation of the SRF-based accelerator research and development facilities at Jefferson Lab. The project to accomplish this, the Technical and Engineering Development Facility (TEDF) Project has completed the first of two phases. An entirely new 3,100 m{sup 2} purpose-built SRF technical work facility has been constructed and was occupied in summer of 2012. All SRF work processes with the exception of cryogenic testing have been relocated into the new building. All cavity fabrication, processing, thermal treatment, chemistry, cleaning, and assembly work is collected conveniently into a new LEED-certified building. An innovatively designed 800 m2 cleanroom/chemroom suite provides long-term flexibility for support of multiple R&D and construction projects as well as continued process evolution. The characteristics of this first 2nd-generation SRF facility are described.

  6. 2nd International Conference on Education and Educational Technology (EET 2011)

    Education Management, Education Theory and Education Application

    2012-01-01

    This volume includes extended and revised versions of a set of selected papers from the 2011 2nd International Conference on Education and Educational Technology (EET 2011) held in Chengdu, China, October 1-2, 2011. The mission of EET 2011 Volume 2 is to provide a forum for researchers, educators, engineers, and government officials involved in the general areas of education management, education theory and education application to disseminate their latest research results and exchange views on the future research directions of these fields. 133 related topic papers were selected into this volume. All the papers were reviewed by 2 program committee members and selected by the volume editor Prof. Yuanzhi Wang, from Intelligent Information Technology Application Research Association, Hong Kong. The conference will bring together leading researchers, engineers and scientists in the domain of interest. We hope every participant can have a good opportunity to exchange their research ideas and results and to discus...

  7. analysis and implementation of reactor protection system circuits - case study Egypt's 2 nd research reactor-

    this work presents a way to design and implement the trip unit of a reactor protection system (RPS) using a field programmable gate arrays (FPGA). instead of the traditional embedded microprocessor based interface design method, a proposed tailor made FPGA based circuit is built to substitute the trip unit (TU), which is used in Egypt's 2 nd research reactor ETRR-2. the existing embedded system is built around the STD32 field computer bus which is used in industrial and process control applications. it is modular, rugged, reliable, and easy-to-use and is able to support a large mix of I/O cards and to easily change its configuration in the future. therefore, the same bus is still used in the proposed design. the state machine of this bus is designed based around its timing diagrams and implemented in VHDL to interface the designed TU circuit

  8. Proceedings of the 2nd joint seminar on atomic collisions and heavy ion induced nuclear reactions

    The meeting of the 2nd joint seminar on atomic collisions and heavy ion induced nuclear reactions was held at the University of Tokyo, May 13 and 14, 1982. The aim of this seminar has been not only to recognize the common problems lying between above two research fields, but also to obtain an overview of the theoretical and experimental approaches to clear the current problems. In the seminar, more than 50 participants gathered and presented 16 papers. These are two general reviews and fourteen comprehensive surveys on topical subjects which have been developed very intensively in recent years. The editors would like to thank all participants for their assistance and cooperation in making possible a publication of these proceedings. (author)

  9. A Perpendicular Biased 2nd Harmonic Cavity for the Fermilab Booster

    Tan, C. Y.; Dey, J. [Fermilab; Madrak, R. L. [Fermilab; Pellico, W. [Fermilab; Romanov, G. [Fermilab; Sun, D. [Fermilab; Terechkine, I. [Fermilab

    2015-07-13

    A perpendicular biased 2nd harmonic cavity is currently being designed for the Fermilab Booster. Its purpose cavity is to flatten the bucket at injection and thus change the longitudinal beam distribution so that space charge effects are decreased. It can also with transition crossing. The reason for the choice of perpendicular biasing over parallel biasing is that the Q of the cavity is much higher and thus allows the accelerating voltage to be a factor of two higher than a similar parallel biased cavity. This cavity will also provide a higher accelerating voltage per meter than the present folded transmission line cavity. However, this type of cavity presents technical challenges that need to be addressed. The two major issues are cooling of the garnet material from the effects of the RF and the cavity itself from eddy current heating because of the 15 Hz bias field ramp. This paper will address the technical challenge of preventing the garnet from overheating.

  10. Proceedings of the 2nd annual meeting of Japanese Society of Radiation Safety Management 2003 Tsukuba

    This is the program and the proceedings of the 2nd annual meeting of Japanese Society of Radiation Safety Management held from December 3rd through the 5th of 2003. The sessions held were: (1) Research on Low-level Waste, (2) Topics related to Detector, Measurement, and Instrument, (3) Dose Level and Imaging Plate, (4) Radiation, (5) Safety Education and Safety Evaluation. The poster sessions held were: (1) Safety Education, Safety Evaluation, Shielding, and so on, (2) Control System and Control Technology, (3) Detector and Radiation Measurement, (4) Topics Related to Imaging Plate, (5) Environment and Radiation Measurement, and (6) Radiation Control. Symposia held were: (1) 'Regarding Basic Concept to Incorporate International Exemption Level in Regulation' as the keynote lecture and (2) 'Regarding Correspondence Associated with Legal Revision and Radiation Safety Regulation'. Regarding these topics, after the explanation from each area, panel discussions were held. (S.K.)

  11. 2nd International Conference on Computer Science, Applied Mathematics and Applications

    Thi, Hoai; Nguyen, Ngoc

    2014-01-01

    The proceedings consists of 30 papers which have been selected and invited from the submissions to the 2nd International Conference on Computer Science, Applied Mathematics and Applications (ICCSAMA 2014) held on 8-9 May, 2014 in Budapest, Hungary. The conference is organized into 7 sessions: Advanced Optimization Methods and Their Applications, Queueing Models and Performance Evaluation, Software Development and Testing, Computational Methods for Mobile and Wireless Networks, Computational Methods for Knowledge Engineering, Logic Based Methods for Decision Making and Data Mining, and Nonlinear Systems and Applications, respectively. All chapters in the book discuss theoretical and practical issues connected with computational methods and optimization methods for knowledge engineering. The editors hope that this volume can be useful for graduate and Ph.D. students and researchers in Computer Science and Applied Mathematics. It is the hope of the editors that readers of this volume can find many inspiring idea...

  12. Belief Functions: Theory and Applications - Proceedings of the 2nd International Conference on Belief Functions

    Masson, Marie-Hélène

    2012-01-01

    The theory of belief functions, also known as evidence theory or Dempster-Shafer theory, was first introduced by Arthur P. Dempster in the context of statistical inference, and was later developed by Glenn Shafer as a general framework for modeling epistemic uncertainty. These early contributions have been the starting points of many important developments, including the Transferable Belief Model and the Theory of Hints. The theory of belief functions is now well established as a general framework for reasoning with uncertainty, and has well understood connections to other frameworks such as probability, possibility and imprecise probability theories.   This volume contains the proceedings of the 2nd International Conference on Belief Functions that was held in Compiègne, France on 9-11 May 2012. It gathers 51 contributions describing recent developments both on theoretical issues (including approximation methods, combination rules, continuous belief functions, graphical models and independence concepts) an...

  13. Boosting biogas yield of anaerobic digesters by utilizing concentrated molasses from 2nd generation bioethanol plant

    Sarker, Shiplu [Department of Renewable Energy, Faculty of Engineering and Science, University of Agder, Grimstad-4879 (Norway); Moeller, Henrik Bjarne [Department of Biosystems Engineering, Faculty of Science and Technology, Aarhus University, Research center Foulum, Blichers Alle, Post Box 50, Tjele-8830 (Denmark)

    2013-07-01

    Concentrated molasses (C5 molasses) from 2nd generation bioethanol plant has been investigated for enhancing productivity of manure based digesters. A batch study at mesophilic condition (35+- 1 deg C) showed the maximum methane yield from molasses as 286 LCH4/kgVS which was approximately 63% of the calculated theoretical yield. In addition to the batch study, co-digestion of molasses with cattle manure in a semi-continuously stirred reactor at thermophilic temperature (50+- 1 deg C) was also performed with a stepwise increase in molasses concentration. The results from this experiment revealed the maximum average biogas yield of 1.89 L/L/day when 23% VSmolasses was co-digested with cattle manure. However, digesters fed with more than 32% VSmolasses and with short adaptation period resulted in VFA accumulation and reduced methane productivity indicating that when using molasses as biogas booster this level should not be exceeded.

  14. Nonlinear Dynamics of Memristor Based 2nd and 3rd Order Oscillators

    Talukdar, Abdul Hafiz

    2011-05-01

    Exceptional behaviours of Memristor are illustrated in Memristor based second order (Wien oscillator) and third order (phase shift oscillator) oscillator systems in this Thesis. Conventional concepts about sustained oscillation have been argued by demonstrating the possibility of sustained oscillation with oscillating resistance and dynamic poles. Mathematical models are also proposed for analysis and simulations have been presented to support the surprising characteristics of the Memristor based oscillator systems. This thesis also describes a comparative study among the Wien family oscillators with one Memristor. In case of phase shift oscillator, one Memristor and three Memristors systems are illustrated and compared to generalize the nonlinear dynamics observed for both 2nd order and 3rd order system. Detail explanations are provided with analytical models to simplify the unconventional properties of Memristor based oscillatory systems.

  15. 2nd international KES conference on Smart Education and Smart e-Learning

    Howlett, Robert; Jain, Lakhmi

    2015-01-01

    This book contains the contributions presented at the 2nd international KES conference on Smart Education and Smart e-Learning, which took place in Sorrento, Italy, June 17-19, 2015. It contains a total of 45 peer-reviewed book chapters that are grouped into several parts: Part 1 - Smart Education, Part 2 – Smart Educational Technology, Part 3 – Smart e-Learning, Part 4 – Smart Professional Training and Teachers’ Education, and Part 5 – Smart Teaching and Training related Topics.  This book can be a useful source of research data and valuable information for faculty, scholars, Ph.D. students, administrators, and practitioners  - those who are interested in innovative areas of smart education and smart e-learning.  .

  16. Enabling the 2nd Generation in Space: Building Blocks for Large Scale Space Endeavours

    Barnhardt, D.; Garretson, P.; Will, P.

    Today the world operates within a "first generation" space industrial enterprise, i.e. all industry is on Earth, all value from space is from bits (data essentially), and the focus is Earth-centric, with very limited parts of our population and industry participating in space. We are limited in access, manoeuvring, on-orbit servicing, in-space power, in-space manufacturing and assembly. The transition to a "Starship culture" requires the Earth to progress to a "second generation" space industrial base, which implies the need to expand the economic sphere of activity of mankind outside of an Earth-centric zone and into CIS-lunar space and beyond, with an equal ability to tap the indigenous resources in space (energy, location, materials) that will contribute to an expanding space economy. Right now, there is no comfortable place for space applications that are not discovery science, exploration, military, or established earth bound services. For the most part, space applications leave out -- or at least leave nebulous, unconsolidated, and without a critical mass -- programs and development efforts for infrastructure, industrialization, space resources (survey and process maturation), non-traditional and persistent security situational awareness, and global utilities -- all of which, to a far greater extent than a discovery and exploration program, may help determine the elements of a 2nd generation space capability. We propose a focus to seed the pre-competitive research that will enable global industry to develop the necessary competencies that we currently lack to build large scale space structures on-orbit, that in turn would lay the foundation for long duration spacecraft travel (i.e. key technologies in access, manoeuvrability, etc.). This paper will posit a vision-to-reality for a step wise approach to the types of activities the US and global space providers could embark upon to lay the foundation for the 2nd generation of Earth in space.

  17. Rectal cancer surgery: volume-outcome analysis.

    Nugent, Emmeline

    2010-12-01

    There is strong evidence supporting the importance of the volume-outcome relationship with respect to lung and pancreatic cancers. This relationship for rectal cancer surgery however remains unclear. We review the currently available literature to assess the evidence base for volume outcome in relation to rectal cancer surgery.

  18. Treatment of locally advanced rectal cancer

    Klaassen, RA; Nieuwenhuijzen, GAP; Martijn, H; Rutten, HJT; Hospers, GAP; Wiggers, T

    2004-01-01

    Historically, locally advanced rectal cancer is known for its dismal prognosis. The treatment of locally advanced rectal cancer is subject to continuous change due to development of new and better diagnostic tools, radiotherapeutic techniques, chemotherapeutic agents and understanding of the subject

  19. Severe rectal complications after prostate brachytherapy

    Purpose: Some investigators have reported severe rectal complications after brachytherapy. Due to the low number of such events, their relationship to dosimetric parameters has not been well characterized. Methods and materials: A total of 3126 patients were treated with low dose rate brachytherapy from 1998 through 2010. 2464 had implant alone, and 313 had implant preceded by 44–46 Gy supplemental external beam radiation (EBRT). Post-implant dosimetry was based on a CT scan obtained on the day of implant, generally within 30 min of the procedure. Every patient’s record was reviewed for occurrence of rectal complications. Results: Eight of 2464 patients (0.32%) treated with brachytherapy alone developed a radiation-related rectal fistula. Average prostatic and rectal dose parameters were moderately higher for fistula patients than for patients without a severe rectal complication. For instance, the average R100 was 1.2 ± 0.75 cc for fistula patients, versus 0.37 ± 0.88 cc for non-fistula patients. However, the fistula patients’ values were well within the range of values for patients without a rectal complication. Four patients had some attempt at repair or reconstruction, but long-term functional outcomes were not favorable. Conclusions: Rectal fistulas are a very uncommon potential complication of prostate brachytherapy, which can occur even in the setting of acceptable day 0 rectal doses. Their occurrence is not easily explained by standard dosimetric or clinical factors

  20. The Morphologic Assessment of Rectal Neuroendocrine Tumors

    Eun Ran Kim

    2014-04-01

    Conclusions: Endoscopic features such as hyperemic change, polypoid lesions, irregular contours, and surface ulcers with tumor size ≥10 mm in diameter are associated with metastasis in rectal NETs. In particular, atypical endoscopic features including hyperemic change, and surface ulcer with tumor size ≥10 mm in diameter may help to predict the risk of metastasis of rectal NETs.

  1. Geochemical evidence of paleogeography and paleoclimate during deposition of the 2nd Member of Kongdian Formation in Kongnan area

    2007-01-01

    The 2nd Member of Kongdian Formation has been made up of a large number of oil shale and mudstone in the Kongnan aera of Huanghua depression around the Bohai Bay. In the Kongnan area, the lake basins were very large and deep during the deposition of the 2nd Member of Kongdian Formation. During that period,the lakes were sealed, uncommunieated with the sea water and the paleoclimate was very warm and wet in Kongnan area. Analyzing the content of the trace element and the rare earth element, carbon and oxygen isotope in the disquisition, The authors prove the two views correct.

  2. Efficacy and Safety of rAAV2-ND4 Treatment for Leber’s Hereditary Optic Neuropathy

    Xing Wan; Han Pei; Min-jian Zhao; Shuo Yang; Wei-kun Hu; Heng He; Si-qi Ma; Ge Zhang; Xiao-yan Dong; Chen Chen; Dao-wen Wang; Bin Li,

    2016-01-01

    Leber’s hereditary optic neuropathy (LHON) is a mitochondrially inherited disease leading to blindness. A mitochondrial DNA point mutation at the 11778 nucleotide site of the NADH dehydrogenase subunit 4 (ND4) gene is the most common cause. The aim of this study was to evaluate the efficacy and safety of a recombinant adeno-associated virus 2 (AAV2) carrying ND4 (rAAV2-ND4) in LHON patients carrying the G11778A mutation. Nine patients were administered rAAV2-ND4 by intravitreal injection to o...

  3. Predictive Factors Study Of Rectal Bleeding Radical Radiotherapy In Prostate Cancer

    Full text: Objective: To determine clinical, para clinical or to predict dosimetric the occurrence of rectal bleeding after radical radiotherapy as primary treatment prostate cancer in patients treated at the National Cancer Institute (Inca) dimensional external beam radiation. Materials and Methods: From July 2008 to July 2011 132 patients were recruited, 86 of which met followed for 12 months. Side effect was recorded gastrointestinal track at different times of the patient with classifications RTOG / EORTC ( Radiation Therapy Oncology Group / European Organization for Research and Treatment of Cancer) and SOMA / LENT also used a questionnaire specifically built and tested by the Italian cooperative group. results were correlated with clinical parameters (PSA, Gleason score, clinical T, class risk, hypertension, and diabetes) and dosimetric ( treatment volume, volume rectum, total dose, maximum dose to the rectum mean dose to the rectum) to assess the correlation thereof with the occurrence of rectal bleeding. Results: In a cut to 12 months follow-up, there is a relationship between the appearance bleeding with time. The mean dose to the rectum and the initial PSA showed significance in correlation with the occurrence of rectal bleeding, with a p of 0.01 and 0.54 respectively. Conclusions: The rectal side effect is one of the major side effects both acute and chronic prostate radiotherapy in the present study has failed to demonstrate a correlation between two factors predictive identified as potentially priori significant the occurrence of rectal bleeding, as the initial PSA and the mean dose to the rectum

  4. Thematic network on the analysis of thorium and its isotopes in workplace materials. Report on the 2nd intercomparison exercise

    Work Package 2 (WP 2) of the EC Thematic Network on ''The analysis of thorium and its isotopes in workplace materials'' is concerned with ''Examination and comparison of analytical techniques for the determination of thorium and its progeny in bulk materials and the development of standards, both for the calibration of associated metrological facilities, and for routine quality control purposes''. The primary objective of WP 2 is ''To evaluate appropriate techniques and determine best practice for analysis of 232Th at workplace levels and environments'', and is to be achieved through a series of intercomparison exercises. Following the results of the 1st intercomparison exercise, a 2nd intercomparison exercise was designed to evaluate the capability of the analytical methods currently being used by European laboratories to determine thorium at very low levels in the presence of a complex inorganic matrix. The intercomparison exercise involved the analysis of three samples of thorium in solution, prepared by the United Kingdom National Physical Laboratory. One sample was the equilibrium solution, analysed in the 1st intercomparison exercise. The other two samples were prepared by dilution of a non-equilibrium thorium solution, one of which was spiked with impurity elements. (i) The results showed a further improvement in the accuracy of measurements in the equilibrium solution, when compared with the results from the 1st intercomparison study. There was an overall drop in u-test values and the number of u-test values above the upper limit of significance fell from 6 to 3. (ii) Overall, participating laboratories also performed well in the analysis of the low level non-equilibrium solutions. However, several laboratories using y-spectrometry had insufficient sensitivity for measurement of low level non-equilibrium sample solutions and did not report results. (iii) There was little evidence that the presence of impurities had a detrimental effect on measurements made

  5. Curriculum on the Edge of Survival: How Schools Fail to Prepare Students for Membership in a Democracy. 2nd Edition

    Heller, Daniel

    2012-01-01

    Typically, school curriculum has been viewed through the lens of preparation for the workplace or higher education, both worthy objectives. However, this is not the only lens, and perhaps not even the most powerful one to use, if the goal is to optimize the educational system. "Curriculum on the Edge of Survival, 2nd Edition," attempts to define…

  6. VALOIR 2012 2nd Workshop on Managing the Client Value Creation Process in Agile Projects: Message from the Chairs

    Pérez, Jennifer; Buglione, Luigi; Daneva, Maya; Dieste, Oscar; Jedlitschka, Andreas; Juristo, Natalia

    2012-01-01

    Welcome to the 2nd Workshop on Managing the Client Value Creation Process in Agile Projects (VALOIR) at the PROFES 2012 conference! The overall goal of VALOIR is to make the knowledge on value creation and management explicit, encouraging the discussion on the use of measurement and estimation appro

  7. Report from the 2nd Summer School in Computational Biology organized by the Queen's University of Belfast

    Frank Emmert-Streib

    2014-12-01

    Full Text Available In this paper, we present a meeting report for the 2nd Summer School in Computational Biology organized by the Queen's University of Belfast. We describe the organization of the summer school, its underlying concept and student feedback we received after the completion of the summer school.

  8. Official report of the 2nd Summer Youth Olympic Games: Nanjing 2014 : Share the Games, share our dreams

    2015-01-01

    The official report of the 2nd Youth Olympic Games is composed of one volume, published in English and available only in electronic form. However, the Nanjing Youth Olympic Games Organising Committee (NYOCOG) has also published a Chinese version, available in print only.

  9. Transition Energy and Oscillator Strength of 1s22p——1s2nd for Fe23+ ion

    WANG Zhi-Wen; LI Xin-Ru; HU Mu-Hong; LIU Ying; WANG Ya-Nan

    2008-01-01

    Transition energies, wavelengths and dipole oscillator strengths of 1s22p - 1s2nd (3 ≤ n ≤ 9) for Fe23+ ion are calculated. The fine structure splittings of 1s2nd (n ≤ 9) states for this ion are also evaluated. The higher-order relativistic contribution to the energy is estimated under a hydrogenic approximation. The quantum defect of Rydberg series 1s2nd is determined according to the quantum defect theory. The energies of any highly excited states with (n ≥ 10) for this series can be reliably predicted using these quantum defects as input. The results in this paper excellently agree with the experimental data available in the literature. Combining the quantum defect theory with the discrete oscillator strengths, the discrete oscillator strengths for the transitions from same given initial state 1s22p to highly excited 1s2nd states (n ≥ 10) and the oscillator strength density corresponding to the bound-free transitions is obtained.

  10. The Influence of Neighborhood Density and Word Frequency on Phoneme Awareness in 2nd and 4th Grades

    Hogan, Tiffany P.; Bowles, Ryan P.; Catts, Hugh W.; Storkel, Holly L.

    2011-01-01

    Purpose: The purpose of this study was to test the hypothesis that two lexical characteristics--neighborhood density and word frequency--interact to influence performance on phoneme awareness tasks. Methods: Phoneme awareness was examined in a large, longitudinal dataset of 2nd and 4th grade children. Using linear logistic test model, the relation…

  11. The Hyphen as a Syllabification Cue in Reading Bisyllabic and Multisyllabic Words among Finnish 1st and 2nd Graders

    Häikiö, Tuomo; Bertram, Raymond; Hyönä, Jukka

    2016-01-01

    Finnish ABC books present words with hyphens inserted at syllable boundaries. Syllabification by hyphens is abandoned in the 2nd grade for bisyllabic words, but continues for words with three or more syllables. The current eye movement study investigated how and to what extent syllable hyphens in bisyllabic ("kah-vi" "cof-fee")…

  12. Conceptual design study of $Nb_{3} Sn$ low-beta quadrupoles for 2nd generation LHC IRs

    Zlobin, A V; Andreev, N; Barzi, E; Bauer, P; Chichili, D R; Huang, Y; Imbasciati, L; Kashikhin, V V; Lamm, M J; Limon, P; Novitski, I; Peterson, T; Strait, J B; Yadav, S; Yamada, R

    2003-01-01

    Conceptual designs of 90-mm aperture high-gradient quadrupoles based on the Nb/sub 3/Sn superconductor, are being developed at Fermilab for possible 2nd generation IRs with the similar optics as in the current low-beta insertions. Magnet designs and results of magnetic, mechanical, thermal and quench protection analysis for these magnets are presented and discussed. (10 refs).

  13. Interstitial irradiation of rectal carcinoma with rectal template

    Ikeda, Hiroshi; Nishiyama, Kinji; Tanaka, Ken; Nakanishi, Makoto; Inoue, Takehiro (Osaka Univ. (Japan). Faculty of Medicine)

    1984-06-01

    Using Iridium-192 wires through a rectal template after Syed, interstitial brachytherapy was conducted in a patient with inoperable adenocarcinoma of the rectum. A 67-year-old man with constipation and change in the stool caliber underwent external radiotherapy (4,000cGy/4W) to the whole pelvis including the perineum, followed by interstitial implant using a template, at the Department of Radiology, Osaka University Hospital. Marked tumor regression, marked circumferential fibrosis and a remarkable decline of CEA titers (pre-RT: 35.8ng/ml, post-RT: 6.2ng/ml) were observed until 7 months post-RT. The domestic production of Iridium-192 wires has made possible the intergrated use of brachytherapy in the perineal region in Japan.

  14. Interstitial irradiation of rectal carcinoma with rectal template

    Using Iridium-192 wires through a rectal template after Syed, interstitial brachytherapy was conducted in a patient with inoperable adenocarcinoma of the rectum. 67-year-old man with constipation and change in the stool caliber underwent external radiotherapy (4,000cGy/4W) to the whole pelvis including the perineum, followed by interstitial implant using a template, at the Department of Radiology, Osaka University Hospital. Marked tumor regression, marked circumferential fibrosis and a remarkable decline of CEA titers (pre-RT: 35.8ng/ml, post-RT: 6.2ng/ml) were observed until 7 months post-RT. The domestic production of Iridium-192 wires has made possible the intergrated use of brachytherapy in the perineal region in Japan. (author)

  15. High-Resolution MRI in Rectal Cancer

    High-resolution MRI is the best method of assessing the relation of the rectal tumor with the potential circumferential resection margin (CRM). Therefore it is currently considered the method of choice for local staging of rectal cancer. The primary surgery of rectal cancer is total mesorectal excision (TME), which plane of dissection is formed by the mesorectal fascia surrounding mesorectal fat and rectum. This fascia will determine the circumferential margin of resection. At the same time, high resolution MRI allows adequate pre-operative identification of important prognostic risk factors, improving the selection and indication of therapy for each patient. This information includes, besides the circumferential margin of resection, tumor and lymph node staging, extramural vascular invasion and the description of lower rectal tumors. All these should be described in detail in the report, being part of the discussion in the multidisciplinary team, the place where the decisions involving the patient with rectal cancer will take place. The aim of this study is to provide the information necessary to understand the use of high resolution MRI in the identification of prognostic risk factors in rectal cancer. The technical requirements and standardized report for this study will be describe, as well as the anatomical landmarks of importance for the total mesorectal excision (TME), as we have said is the surgery of choice for rectal cancer. (authors)

  16. Severe weather phenomena: SQUALL LINES The case of July 2nd 2009

    Paraschivescu, Mihnea; Tanase, Adrian

    2010-05-01

    The wind intensity plays an important role, among the dangerous meteorological phenomena, to produce negative effects on the economy and the social activities, particularly when the wind is about to turn into a storm. During the past years one can notice an increase of wind frequency and intensity due to climate changes and, consequently, as a result of the extreme meteorological phenomena not only on a planetary level but also on a regional one. Although dangerous meteorological phenomena cannot be avoided, since they are natural, nevertheless they can be anticipated and decision making institutions and mass media can be informed. This is the reason why, in this paper, we set out to identify the synoptic conditions that led to the occurrence of the severe storm case in Bucharest on July 2nd, 2009, as well as the matrices that generate such cases. At the same time we sought to identify some indications evidence especially from radar data so as to lead to the improvement of the time interval between the nowcasting warning and the actual occurrence of the phenomenon.

  17. Geodesign from Theory to Practice: From Metaplanning to 2nd Generation of Planning Support Systems

    Michele Campagna

    2014-05-01

    Full Text Available This paper deals with the concept of Geodesign, a new approach to spatial planning and design which is grounded on extensive use of Geographic Information Science methods and tools. As a method Geodesign is intended to inform projects since their conceptualization, to analysis and diagnosis, to design of alternatives and impact simulation, and eventually the final choice. This approach appears particularly urgent and actual to many scholars from academia and practitioners from the industry and the planning practice for advances in GIScience nowadays offer unprecedented data and tools to manage territorial knowledge for decision-making support. The author argues research in Geodesign may contribute to solve major actual pitfalls in sustainable spatial planning: namely it may offer methods to help planners to inform sustainable design alternatives with environmental considerations and contextually assess their impacts; secondly, it may help to ensure more transparent, responsible, and accountable democratic decision-making processes. The argumentation is supported by the author recent research results with regards to the evolution from 1st generation Planning Support Systems (PSS, to metaplanning and 2nd generation PSS.

  18. Production of artificial ionospheric layers by frequency sweeping near the 2nd gyroharmonic

    T. Pedersen

    2011-01-01

    Full Text Available Artificial ionospheric plasmas descending from the background F-region have been observed on multiple occasions at the High Frequency Active Auroral Research Program (HAARP facility since it reached full 3.6 MW power. Proximity of the transmitter frequency to the 2nd harmonic of the electron gyrofrequency (2fce has been noted as a requirement for their occurrence, and their disappearance after only a few minutes has been attributed to the increasing frequency mismatch at lower altitudes. We report new experiments employing frequency sweeps to match 2fce in the artificial plasmas as they descend. In addition to revealing the dependence on the 2fce resonance, this technique reliably produces descending plasmas in multiple transmitter beam positions and appears to increase their stability and lifetime. High-speed ionosonde measurements are used to monitor the altitude and density of the artificial plasmas during both the formation and decay stages.

  19. CELEBRATED APRIL 2nd – INTERNATIONAL DAY OF PERSONS WITH AUTISM

    Manuela KRCHANOSKA

    2014-09-01

    Full Text Available On April 2nd, the Macedonian Scientific Society for Autism, for the fourth time organized an event on the occasion of the International Day of Persons with Autism. The event with cultural and artistic character was held at the Museum of the Macedonian Struggle under the motto “They are not alone, we are with them”. The huge number of citizens only confirmed the motto. It seemed that the hall of the Museum of the Macedonian Struggle is too small for the warm hearts of the audience. More than 300 guests were present in the hall, among which there were children with autism and their families, prominent professors, doctors, special educators and rehabilitators, psychologists, students and other citizens with glad heart and will who decided to enrich the event with their presence. The event was opened by the violinist Plamenka Trajkovska, which performed one song. After her, the President of the Macedonian Scientific Society for Autism, PhD. Vladimir Trajkovski delivered his speech. The professor told the parents of autistic children, who were present in large number, not to lose hope, to fight for their children, and that the Macedonian Scientific Society for Autism will provide tremendous support and assistance in this struggle.

  20. Deaf-mute teaching during the Spanish 2nd Republic period. A historical view

    Alfredo ALCINA MADUEÑO

    2011-07-01

    Full Text Available Deaf-mute teaching during the Spanish 2nd Republic period is an issue which has never been studied in depth consideration and some of its aspects have been not even touched by any research. We could say that deaf-mute education is granted with the characteristics found in general education, at least regarding this specific stage, mainly: economic and budget thoughtful following effort by the governments, methodological renovation, modernization of the educative system, spreading of the school-net, teachers’ formation, etcetera. However it is true that we can fin a very strict-stated idiosyncrasy, which sometimes turns out to be even controversial, not only due to the opposition of different political parties in power during different 2-years periods (31/37 and 34/35, but also because of the republican-socialist governments decisions regarding educative policy. The Republican legacy consists actually much more in documentary facts than in actual realisations, and will have much more application within that political regime that follows and annihilates the Republic than within the period of the Republic itself. The consideration of primary sources (both legal and documental is the base that supports the final conclusions that are provided by means of this exposition.

  1. Proceedings of the 2nd CSNI Specialist Meeting on Simulators and Plant Analysers

    The safe utilisation of nuclear power plants requires the availability of different computerised tools for analysing the plant behaviour and training the plant personnel. These can be grouped into three categories: accident analysis codes, plant analysers and training simulators. The safety analysis of nuclear power plants has traditionally been limited to the worst accident cases expected for the specific plant design. Many accident analysis codes have been developed for different plant types. The scope of the analyses has continuously expanded. The plant analysers are now emerging tools intended for extensive analysis of the plant behaviour using a best estimate model for the whole plant including the reactor and full thermodynamic process, both combined with automation and electrical systems. The comprehensive model is also supported by good visualisation tools. Training simulators with real time plant model are tools for training the plant operators to run the plant. Modern training simulators have also features supporting visualisation of the important phenomena occurring in the plant during transients. The 2nd CSNI Specialist Meeting on Simulators and Plant Analysers in Espoo attracted some 90 participants from 17 countries. A total of 49 invited papers were presented in the meeting in addition to 7 simulator system demonstrations. Ample time was reserved for the presentations and informal discussions during the four meeting days. (orig.)

  2. Academic Training - 2nd Term: 08.01.2007 - 31.03.2007

    2006-01-01

    2006 - 2007 ACADEMIC TRAINING PROGRAMME 2nd Term : 08.01.2007 - 31.03.2007 LECTURE SERIES Applied Superconductivity by V. Palmieri, INFN, Padova, It. 17, 18, 19 January 11:00 -1200 - Auditorium, Bldg 500 String Theory for Pedestrians by B. Zwiebach, M.I.T. Cambridge, USA 29, 30, 31 January 11:00-12:00 - Auditorium, Bldg 500 on 29, 30 January TH Auditorium on 31 January Introduction to Supersymmetry by D. Kaplan, John Hopkins University, Baltimore, USA 12, 13, 14, 15 February 11:00-12:00 - Auditorium, Bldg 500 The Hunt for the Higgs Particle by F. Zwirner, University of Padova, It 27, 28 February, 1st March 11:00-12:00 - Auditorium, Bldg 500 From Evolution Theory to Parallel and Distributed Genetic by F. Fernandez de Vega 15, 16, March 11:00-12:00 - Auditorium, Bldg 500 The lectures are open to all those interested, without application. The abstract of the lectures, as well as any change to the above information (title, dates, time, place etc.) will be published in the CERN bulletin, the WWW, an...

  3. Academic Training - 2nd Term: 08.01.2007 - 31.03.2007

    2006-01-01

    2006 - 2007 ACADEMIC TRAINING PROGRAMME 2nd Term : 08.01.2007 - 31.03.2007 LECTURE SERIES Applied Superconductivity by V. Palmieri, INFN, Padova, It. 17, 18, 19 January 11:00 -1200 - Auditorium, bldg. 500 String Theory for Pedestrians by B. Zwiebach, M.I.T. Cambridge, USA 29, 30, 31 January 11:00-12:00 - Auditorium, bldg. 500 on 29, 30 January TH Auditorium on 31 January Introduction to Supersymmetry by D. Kaplan, John Hopkins University, Baltimore, USA 12, 13, 14, 15 February 11:00-12:00 - Auditorium, bldg. 500 The Hunt for the Higgs Particle by F. Zwirner, University of Padova, It 27, 28 February, 1st March 11:00-12:00 - Auditorium, bldg. 500 From Evolution Theory to Parallel and Distributed Genetic Programming by F. Fernandez de Vega 15, 16, March 11:00-12:00 - Auditorium, bldg. 500 The lectures are open to all those interested, without application. The abstract of the lectures, as well as any change to the above information (title, dates, time, place etc.) will be published in the WWW, and ...

  4. DRS // CUMULUS Oslo 2013. The 2nd International Conference for Design Education Researchers

    Liv Merete Nielsen

    2013-01-01

    Full Text Available 14-17 May 2013, Oslo, NorwayWe have received more than 200 full papers for the 2nd International Conference for Design Education Researchers in Oslo.This international conference is a springboard for sharing ideas and concepts about contemporary design education research. Contributors are invited to submit research that deals with different facets of contemporary approaches to design education research. All papers will be double-blind peer-reviewed. This conference is open to research in any aspect and discipline of design educationConference themeDesign Learning for Tomorrow - Design Education from Kindergarten to PhDDesigned artefacts and solutions influence our lives and values, both from a personal and societal perspective. Designers, decision makers, investors and consumers hold different positions in the design process, but they all make choices that will influence our future visual and material culture. To promote sustainability and meet global challenges for the future, professional designers are dependent on critical consumers and a design literate general public.  For this purpose design education is important for all. We propose that design education in general education represents both a foundation for professional design education and a vital requirement for developing the general public’s competence for informed decision making.REGISTRATION AT http://www.hioa.no/DRScumulus

  5. Improved beam spot measurements in the 2nd generation proton beam writing system

    Nanosized ion beams (especially proton and helium) play a pivotal role in the field of ion beam lithography and ion beam analysis. Proton beam writing has shown lithographic details down to the 20 nm level, limited by the proton beam spot size. Introducing a smaller spot size will allow smaller lithographic features. Smaller probe sizes, will also drastically improve the spatial resolution for ion beam analysis techniques. Among many other requirements, having an ideal resolution standard, used for beam focusing and a reliable focusing method, is an important pre-requisite for sub-10 nm beam spot focusing. In this paper we present the fabrication processes of a free-standing resolution standard with reduced side-wall projection and high side-wall verticality. The resulting grid is orthogonal (90.0° ± 0.1), has smooth edges with better than 6 nm side-wall projection. The new resolution standard has been used in focusing a 2 MeV H2+ beam in the 2nd generation PBW system at Center for Ion Beam Applications, NUS. The beam size has been characterized using on- and off-axis scanning transmission ion microscopy (STIM) and ion induced secondary electron detection, carried out with a newly installed micro channel plate electron detector. The latter has been shown to be a realistic alternative to STIM measurements, as the drawback of PIN diode detector damage is alleviated. With these improvements we show reproducible beam focusing down to 14 nm

  6. Boundary value problems for the 2nd-order Seiberg-Witten equations

    Celso Melchiades Doria

    2005-02-01

    Full Text Available It is shown that the nonhomogeneous Dirichlet and Neuman problems for the 2nd-order Seiberg-Witten equation on a compact 4-manifold X admit a regular solution once the nonhomogeneous Palais-Smale condition ℋ is satisfied. The approach consists in applying the elliptic techniques to the variational setting of the Seiberg-Witten equation. The gauge invariance of the functional allows to restrict the problem to the Coulomb subspace 𝒞αℭ of configuration space. The coercivity of the 𝒮𝒲α-functional, when restricted into the Coulomb subspace, imply the existence of a weak solution. The regularity then follows from the boundedness of L∞-norms of spinor solutions and the gauge fixing lemma.

  7. Study of Application for Excursion Observation Method in Primary School 2nd Grade Social Studies

    Ahmet Ali GAZEL

    2014-04-01

    Full Text Available This study aims to investigate how field trips are conducted at 2nd grade of primary schools as a part of social studies course. Data for this research is compiled from 143 permanent Social Studies teachers working throughout 2011–2012 Education Year in the primary schools of central Kütahya and its districts. Data is compiled by using descriptive search model. In the research, after taking expert opinions, a measuring tool developed by the researcher is used. Data obtained from the research were transferred to computer, and analyses were made. In the analysis of the data, frequency and percentage values have been used to determine the distribution. Also a single factor variance analysis and t-test for independent samples have been used to determine the significance of difference between the variables. As a result of the research, it has been realized that insufficient importance is given to field trip method in Social Studies lessons. Most of the teachers using this method apply it in spring months. Teachers usually make use of field trips independent from unit/topic to increase the students’ motivation, and they generally use verbal expression in the class after tours. The biggest difficulty teachers encounter while using tour-observation method is the students’ undisciplined behavior.

  8. The 2nd and 3rd lower molars development of in utero gamma irradiated mouse fetus and neonates

    Pregnant mothers were irradiated by a single dose of gamma rays (0, 2, 4, 6 Gy cobalt 60) in the days 10, 12, 14, 16, 18 of pregnancy. The heads of the embryos, and those of the neonates were taken at consecutive intervals of irradiation, starting from 16 days of pregnancy till 3rd day after delivery. The effect of irradiation was investigated in the development of the 2nd and 3rd lower molars on serial tissue sections, within consecutive periods of their organogenesis. Irradiation led to growth-deficiency in the 2nd and 3rd molars, and causes delay in their development. This was observed in various degree depending on the dose, time of irradiation, and time after irradiation. This belated development was manifested in morphogenesis, histogenesis, and odontoblasts and ameloblastis cyto and functional differentiations. The study showed that the delay in the development-stages of the 2nd lower molar, under control, if compared with the same process, to which is exposed, the 1st lower molar - within two days difference - dose not diminish the later irradiation effect on the 2nd molar, when compared with the immediate irradiation effect in the 1st molar (demonstrated in a previous study by Osman and Al-Achkar, 2001). On the contrary, the present study showed that the 2nd lower molar is more radiosensitive to various doses than the 1st lower molar. Also it showed the irradiation with two doses 4 and 6 Gy leads to a delay in the formation of the 3rd lower molar's bud, and it does not go deeper beyond the lower molar. (Author)

  9. SrAl2O4∶Eu2+, Nd3+ and Dy3+ Long Afterglow Phosphor

    何大伟; 吕菁华; 崔兴龙

    2003-01-01

    The SrAl2O4∶Eu2+, Nd3+ and SrAl2O4∶Eu2+, Dy3+ long afterglow phosphor were synthesized. Their excitation and emission spectra at different excitation and afterglow characteristics were analyzed after the excitation power was taken off. The effects of Eu2+, Dy3+, Nd3+ mole concentrations on phosphorescence characteristics were also discussed. It is crucial to have trapping levels located at a suitable depth related to the thermal release rate at room temperature. The incorporation of Nd3+ ions as an auxiliary activator into the SrAl2O4∶Eu2+ system causes very intense and long phosphorescence. The response time of SrAl2O4∶Eu2+, Dy3+ phosphors is quicker than that of SrAl2O4∶Eu2+, Nd3+. Phosphorescence characteristics of SrAl2O4∶Eu2+, Nd3+ is much better than those of SrAl2O4∶Eu2+, Dy3+. The integrate area of the excitation spectrum of SrAl2O4∶Eu2+, Nd3+ phosphor is larger than that of SrAl2O4∶Eu2+, Dy3+ phosphor within the range of 250~360 nm. For phosphorescence characteristics to the system of SrAl2O4∶Eu2+, Nd3+ phosphor, the optimum concentration of Nd3+ trivalent rare earth ions is 0.05 mol.

  10. PET-MRI in Diagnosing Patients With Colon or Rectal Cancer

    2015-11-25

    Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IIA Colon Cancer; Stage IIA Rectal Cancer; Stage IIB Colon Cancer; Stage IIB Rectal Cancer; Stage IIC Colon Cancer; Stage IIC Rectal Cancer; Stage IIIA Colon Cancer; Stage IIIA Rectal Cancer; Stage IIIB Colon Cancer; Stage IIIB Rectal Cancer; Stage IIIC Colon Cancer; Stage IIIC Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer

  11. Rectal Duplication Cyst: A Rare Cause of Rectal Prolapse in a Toddler.

    Khushbakht, Samreen; ul Haq, Anwar

    2015-12-01

    Rectal duplication cysts are rare congenital anomalies. They constitute only 4% of the total gastrointestinal anomalies. They usually present in childhood. The common presenting symptoms are mass or pressure effects like constipation, tenesmus, urinary retention, local infection or bleeding due to presence of ectopic gastric mucosa. We are reporting a rare presenting symptom of rectal duplication cyst in a 4-year-old boy/toddler who presented with rectal prolapse. He also had bleeding per rectum. Rectal examination revealed a soft mass palpable in the posterior rectal wall. CT scan showed a cystic mass in the posterior wall of the rectum. It was excised trans-anally and the postoperative recovery was uneventful. Biopsy report showed rectal duplication cyst. PMID:26691370

  12. MRI staging of low rectal cancer

    Shihab, Oliver C.; Heald, Richard J. [Pelican Cancer Foundation, North Hampshire Hospital, Basingstoke (United Kingdom); Moran, Brendan J. [Colorectal Research Unit, North Hampshire Hospital, Basingstoke (United Kingdom); Quirke, Philip [St James' s Hospital, Leeds Institute for Molecular Medicine, Leeds (United Kingdom); Brown, Gina [Royal Marsden Hospital, Department of Radiology, Surrey (United Kingdom)

    2009-03-15

    Low rectal tumours, especially those treated by abdominoperineal excision (APE), have a high rate of margin involvement when compared with tumours elsewhere in the rectum. Correct surgical management to minimise this rate of margin involvement is reliant on highly accurate imaging, which can be used to plan the planes of excision. In this article we describe the techniques for accurate magnetic resonance imaging (MRI) assessment and a novel staging system for low rectal tumours. Using this staging system it is possible for the radiologist to demonstrate accurately tumour-free planes for surgical excision of low rectal tumours. (orig.)

  13. MRI staging of low rectal cancer

    Low rectal tumours, especially those treated by abdominoperineal excision (APE), have a high rate of margin involvement when compared with tumours elsewhere in the rectum. Correct surgical management to minimise this rate of margin involvement is reliant on highly accurate imaging, which can be used to plan the planes of excision. In this article we describe the techniques for accurate magnetic resonance imaging (MRI) assessment and a novel staging system for low rectal tumours. Using this staging system it is possible for the radiologist to demonstrate accurately tumour-free planes for surgical excision of low rectal tumours. (orig.)

  14. Transvaginal ultrasonography of rectal endometriosis

    Egekvist, Anne Gisselmann; Seyer-Hansen, Mikkel; Forman, Axel

    Objectives: The aim of this present study was to evaluate the interobserver variation of transvaginal ultrasonographic measurements of endometriosis infiltrating the rectosigmoid wall. Methods: Transvaginal ultrasonography was performed independently by two observers. Observer 1 had several years...... of experience in ultrasonography while observer 2 was a medical student with no prior experience in ultrasonography or endometriosis. In 24 patient length, width and depth of endometriosis infiltrating the rectosigmoid bowel was measured. The differences between the observers were analysed by Bland...... ultrasonography for a relatively short period gives comparable scanning results between the two observers. It seems that transvaginal ultrasound could be used as a diagnostic tool for rectal endometriosis in most departments. However, the irregular morphology of the lesions makes the measurements very complex...

  15. How useful is rectal endosonography in the staging of rectal cancer?

    Taylan; Kav; Yusuf; Bayraktar

    2010-01-01

    It is essential in treating rectal cancer to have adequate preoperative imaging,as accurate staging can influence the management strategy,type of resection,and candidacy for neoadjuvant therapy.In the last twenty years,endorectal ultrasound(ERUS) has become the primary method for locoregional staging of rectal cancer.ERUS is the most accurate modality for assessing local depth of invasion of rectal carcinoma into the rectal wall layers(T stage) .Lower accuracy for T2 tumors is commonly reported,which could ...

  16. The Influence of Instructional Climates on Time Spent in Management Tasks and Physical Activity of 2nd-Grade Students during Physical Education

    Logan, Samuel W.; Robinson, Leah E.; Webster, E. Kipling; Rudisill, Mary E.

    2015-01-01

    The purpose of this study is to determine the effect of two physical education (PE) instructional climates (mastery, performance) on the percentage of time students spent in a) moderate-to-vigorous physical activity (MVPA) and b) management tasks during PE in 2nd-grade students. Forty-eight 2nd graders (mastery, n = 23; performance, n = 25)…

  17. Low Rectal Cancer Study (MERCURY II)

    2016-03-11

    Adenocarcinoma; Adenocarcinoma, Mucinous; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Cystic, Mucinous, and Serous; Colorectal Neoplasms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Digestive System Diseases; Gastrointestinal Diseases; Intestinal Diseases; Rectal Diseases

  18. Wind sock deformity in rectal atresia

    Rectal atresia is a rare anorectal deformity. It usually presents with neonatal obstruction and it is often a complete membrane or severe stenosis. Windsock deformity has not been reported in rectal atresia especially, having been missed for 2 years. A 2-year-old girl reported only a severe constipation despite having a 1.5-cm anal canal in rectal examination with scanty discharge. She underwent loop colostomy and loopogram, which showed a wind sock deformity of rectum with mega colon. The patient underwent abdominoperineal pull-through with good result and follow-up. This is the first case of the wind sock deformity in rectal atresia being reported after 2 years of age. (author)

  19. Treatment Options by Stage (Rectal Cancer)

    ... Treatment Genetics of Colorectal Cancer Age and family history can affect the risk of rectal cancer. Anything ... to flow from the body to a collection bag. After the cancer is removed, the surgeon will ...

  20. Wind sock deformity in rectal atresia

    Hosseini Seyed

    2009-01-01

    Full Text Available Rectal atresia is a rare anorectal deformity. It usually presents with neonatal obstruction and it is often a complete membrane or severe stenosis. Windsock deformity has not been reported in rectal atresia especially, having been missed for 2 years. A 2-year-old girl reported only a severe constipation despite having a 1.5-cm anal canal in rectal examination with scanty discharge. She underwent loop colostomy and loopogram, which showed a wind sock deformity of rectum with mega colon. The patient underwent abdominoperineal pull-through with good result and follow-up. This is the first case of the wind sock deformity in rectal atresia being reported after 2 years of age.

  1. Mechanosensitivity of the 2nd Kind: TGF-β Mechanism of Cell Sensing the Substrate Stiffness

    Cockerill, Max; Rigozzi, Michelle K.; Terentjev, Eugene M.

    2015-01-01

    Cells can sense forces applied to them, but also the stiffness of their environment. These are two different phenomena, and here we investigate the mechanosensitivity of the 2nd kind: how the cell can measure an elastic modulus at a single point of adhesion—and how the cell can receive and interpret the chemical signal released from the sensor. Our model uses the example of large latent complex of TGF-β as a sensor. Stochastic theory gives the rate of breaking of latent complex, which initiates the signaling feedback loop after the active TGF-β release and leads to a change of cell phenotype driven by the α-smooth muscle actin. We investigate the dynamic and steady-state behaviors of the model, comparing them with experiments. In particular, we analyse the timescale of approach to the steady state, the stability of the non-linear dynamical system, and how the steady-state concentrations of the key markers vary depending on the elasticity of the substrate. We discover a crossover region for values of substrate elasticity closely corresponding to that of the fibroblast to myofibroblast transition. We suggest that the cell could actively vary the parameters of its dynamic feedback loop to ‘choose’ the position of the transition region and the range of substrate elasticity that it can detect. In this way, the theory offers the unifying mechanism for a variety of phenomena, such as the myofibroblast conversion in fibrosis of wounds and lungs and smooth muscle cell dysfunction in cardiac disease. PMID:26448620

  2. 2nd international expert meeting straw power; 2. Internationale Fachtagung Strohenergie

    NONE

    2012-06-15

    Within the 2nd Guelzow expert discussions at 29th to 30th March, 2012 in Berlin (Federal Republic of Germany), the following lectures were held: (1) Promotion of the utilisation of straw in Germany (A. Schuette); (2) The significance of straw in the heat and power generation in EU-27 member states in 2020 and in 2030 under consideration of the costs and sustainability criteria (C. Panoutsou); (3) State of he art of the energetic utilization of hay goods in Europe (D. Thraen); (4) Incineration technological characterisation of straw based on analysis data as well as measured data of large-scale installations (I. Obernberger); (5) Energetic utilization of hay goods in Germany (T. Hering); (6) Actual state of the art towards establishing the first German straw thermal power station (R. Knieper); (7) Straw thermal power plants at agricultural sow farms and poultry farms (H. Heilmann); (8) Country report power from straw in Denmark (A. Evald); (9) Country report power from straw in Poland (J. Antonowicz); (10) Country report power from straw in China (J. Zhang); (11) Energetic utilisation of straw in Czechia (D. Andert); (12) Mobile pelletization of straw (S. Auth); (13) Experiences with the straw thermal power plant from Vattenfall (N. Kirkegaard); (14) Available straw potentials in Germany (potential, straw provision costs) (C. Weiser); (15) Standardization of hay good and test fuels - Classification and development of product standards (M. Englisch); (16) Measures of reduction of emissions at hay good incinerators (V. Lenz); (17) Fermentation of straw - State of the art and perspectives (G. Reinhold); (18) Cellulosis - Ethanol from agricultural residues - Sustainable biofuels (A. Hartmair); (19) Syngas by fermentation of straw (N. Dahmen); (20) Construction using straw (D. Scharmer).

  3. Re-fighting the 2nd Anglo-Boer War: historians in the trenches

    Ian Van der Waag

    2012-02-01

    Full Text Available Some one hundred years ago, South Africa was tom apart by the 2nd Anglo- Boer War (1899-1902. The war was a colossal psychological experience fought at great expense: It cost Britain twenty-two thousand men and £223 million. The social, economic and political cost to South Africa was greater than the statistics immediately indicate: at least ten thousand fighting men in addition to the camp deaths, where a combination of indifference and incompetence resulted in the deaths of 27 927 Boers and at least 14 154 Black South Africans. Yet these numbers belie the consequences. It was easy for the British to 'forget' the pain of the war, which seemed so insignificant after the losses sustained in 1914-18. With a long history of far-off battles and foreign wars, the British casualties of the Anglo-Boer War became increasingly insignificant as opposed to the lesser numbers held in the collective Afrikaner mind. This impact may be stated somewhat more candidly in terms of the war participation ratio for the belligerent populations. After all, not all South Africans fought in uniform. For the Australian colonies these varied between 4½per thousand (New South Wales to 42.3 per thousand (Tasmania. New Zealand 8 per thousand, Britain 8½ per thousand: and Canada 12.3 per thousand; while in parts of South Africa this was perhaps as high as 900 per thousand. The deaths and high South African participation ratio, together with the unjustness of the war in the eyes of most Afrikaners, introduced bitterness, if not a hatred, which has cast long shadows upon twentieth-century South Africa.

  4. The Ratio of 2nd to 4th Digit Length in Korean Alcohol-dependent Patients

    Han, Changwoo; Bae, Hwallip; Lee, Yu-Sang; Won, Sung-Doo; Kim, Dai Jin

    2016-01-01

    Objective The ratio of 2nd to 4th digit length (2D:4D) is a sexually dimorphic trait. Men have a relatively shorter second digit than fourth digit. This ratio is thought to be influenced by higher prenatal testosterone level or greater sensitivity to androgen. The purpose of this study is to investigate the relationship between alcohol dependence and 2D:4D in a Korean sample and whether 2D:4D can be a biologic marker in alcohol dependence. Methods In this study, we recruited 87 male patients with alcohol dependence from the alcohol center of one psychiatric hospital and 52 healthy male volunteers who were all employees in the same hospital as controls. We captured images of the right and left hands of patients and controls using a scanner and extracted data with a graphics program. We measured the 2D:4D of each hand and compared the alcohol dependence group with the control group. We analyzed these ratios using an independent-samples t-test. Results The mean 2D:4D of patients was 0.934 (right hand) and 0.942 (left hand), while the mean 2D:4D of controls was 0.956 (right hand) and 0.958 (left hand). Values for both hands were significantly lower for patients than controls (p<0.001, right hand; p=0.004, left hand). Conclusion Patients who are alcohol dependent have a significantly lower 2D:4D than controls, similar to the results of previous studies, which suggest that a higher prenatal testosterone level in the gonadal period is related to alcoholism. Furthermore, 2D:4D is a possible predictive marker of alcohol dependence. PMID:27121425

  5. MicroRNA in rectal cancer

    Azizian, Azadeh; Gruber, Jens; Ghadimi, B. Michael; Gaedcke, Jochen

    2016-01-01

    In rectal cancer, one of the most common cancers worldwide, the proper staging of the disease determines the subsequent therapy. For those with locally advanced rectal cancer, a neoadjuvant chemoradiotherapy (CRT) is recommended before any surgery. However, response to CRT ranges from complete response (responders) to complete resistance (non-responders). To date we are not able to separate in advance the first group from the second, due to the absence of a valid biomarker. Therefore all pati...

  6. The 2nd CAAP Convention & International Symposium on Modern and Contemporary English Literatures (June 8 -9, 2013 )%The 2nd CAAP Convention & International Symposium on Modern and Contemporary English Literatures (June 8 -9, 2013 )

    2012-01-01

    In order to further promote literary scholarship and international academic exchange, the University of Pennsylvania-based Chinese/American Association for Poetry and Poetics (CAAP) will collaborate with the School of Foreign Languages and School of Humanities of Central China Normal University, Foreign Literature Studies, and Forum for World Literature Studies in hosting "The 2nd CAAP Convention and International Symposium on Literatures in English" (June 8 -9, 2013) in Wuhan, China. Scholars and writers all over the world are welcome.

  7. Proceedings of the 2nd Iberian Nuclear Astrophysics Meeting on Compact Stars

    Perez-Garcia, M A; Eds, C Albertus; 10.1088/1742-6596/342/1/011001

    2012-01-01

    This volume contains most of the links to the presentations delivered at this international workshop. This meeting was the second in the series following the previous I Encuentro Ib\\'erico de Compstar, held at the University of Coimbra, Portugal in 2010. The main purpose of this meeting was to strengthen the scientific collaboration between the participants of the Iberian and the rest of the southern European branches of the European Nuclear Astrophysics network, formerly, COMPSTAR. This ESF (European Science Foundation) supported network has been crucial in helping to make a broader audience for the the most interesting and relevant research lines being developed currently in Nuclear Astrophysics, especially related to the physics of neutron stars. The program of the meeting was tailored to theoretical descriptions of the physics of neutron stars although some input from experimental observers and other condensed matter and optics areas of interest was also included.

  8. Endoscopic findings of rectal mucosal damage after pelvic radiotherapy for cervical carcinoma: correlation of rectal mucosal damage with radiation dose and clinical symptoms

    Kim, Tae Gyu; Huh, Seung Jae; Park, Won [Dept. of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2013-06-15

    To describe chronic rectal mucosal damage after pelvic radiotherapy (RT) for cervical cancer and correlate these findings with clinical symptoms and radiation dose. Thirty-two patients who underwent pelvic RT were diagnosed with radiation-induced proctitis based on endoscopy findings. The median follow-up period was 35 months after external beam radiotherapy (EBRT) and intracavitary radiotherapy (ICR). The Vienna Rectoscopy Score (VRS) was used to describe the endoscopic findings and compared to the European Organization for Research and Treatment of Cancer (EORTC)/Radiation Therapy Oncology Group (RTOG) morbidity score and the dosimetric parameters of RT (the ratio of rectal dose calculated at the rectal point [RP] to the prescribed dose, biologically effective dose [BED] at the RP in the ICR and EBRT plans, {alpha}/{beta} = 3). Rectal symptoms were noted in 28 patients (rectal bleeding in 21 patients, bowel habit changes in 6, mucosal stools in 1), and 4 patients had no symptoms. Endoscopic findings included telangiectasia in 18 patients, congested mucosa in 20, ulceration in 5, and stricture in 1. The RP ratio, BEDICR, BEDICR+EBRT was significantly associated with the VRS (RP ratio, median 76.5%; BEDICR, median 37.1 Gy3; BEDICR+EBRT, median 102.5 Gy3; p < 0.001). The VRS was significantly associated with the EORTC/RTOG score (p = 0.038). The most prevalent endoscopic findings of RT-induced proctitis were telangiectasia and congested mucosa. The VRS was significantly associated with the EORTC/RTOG score and RP radiation dose.

  9. Proceedings of 2nd Korea-China Congress of Nuclear Medicine and the Korean Society Nuclear Medicine Spring Meeting 2000

    This proceedings contains articles of 2nd Korea-China Congress of Nuclear Medicine and 2000 spring meeting of the Korean Society Nuclear Medicine. It was held on May 17-19, 2000 in Seoul, Korean. This proceedings is comprised of 6 sessions. The subject titles of session are as follows: general nuclear medicine, neurology, oncology, radiopharmacy and biology, nuclear cardiology, nuclear cardiology: physics and instrumentation and so on. (Yi, J. H.)

  10. Teachers' Spatial Anxiety Relates to 1st-and 2nd-Graders' Spatial Learning

    Gunderson, Elizabeth A.; Ramirez, Gerardo; Beilock, Sian L.; Levine, Susan C.

    2013-01-01

    Teachers' anxiety about an academic domain, such as math, can impact students' learning in that domain. We asked whether this relation held in the domain of spatial skill, given the importance of spatial skill for success in math and science and its malleability at a young age. We measured 1st-and 2nd-grade teachers' spatial anxiety…

  11. Multi-objective Optimization of a Solar Assisted 1st and 2nd Generation Sugarcane Ethanol Production Plant

    Zevenhoven, Ron; Wallerand, Anna Sophia; Queiroz Albarelli, Juliana; Viana Ensinas, Adriano; Ambrosetti, Gianluca; Mian, Alberto; Maréchal, François

    2014-01-01

    Ethanol production sites utilizing sugarcane as feedstock are usually located in regions with high land availability and decent solar radiation. This offers the opportunity to cover parts of the process energy demand with concentrated solar power (CSP) and thereby increase the fuel production and carbon conversion efficiency. A plant is examined that produces 1st and 2nd generation ethanol by fermentation of sugars (from sugarcane) and enzymatic hydrolysis of the lignocellulosic residues (bag...

  12. Evolution of Corruption in Sub-Saharan Africa - from Nkruma to Mutharika The 2nd: Case Study Of South Africa

    Mavhungu Abel Mafukata

    2016-01-01

    Since Sub-Saharan Africa's first independence in Ghana, the region has experienced massive and costly political and bureaucratic corruption within public service and administration. The causes of the corruption, its nature and form are wide and intertwined. In Sub-Saharan Africa, efforts to curb corruption have failed to discard it. The paper focused on the period from Nkruma in Ghana to Mutharika the 2nd in Malawi. This paper reviewed existing literature on political and bureaucratic corrupt...

  13. 2nd Joint GOSUD/SAMOS Workshop, U.S.Coast Guard Base, Seattle, Washington, 10-12 June 2008.

    2008-01-01

    On 10-12 June 2008, the NOAA Climate Observation Division sponsored the 2nd Joint Global Ocean Surface Underway Data (GOSUD)/Shipboard Automated Meteorological and Oceanographic System (SAMOS) Workshop in Seattle, WA, USA. The workshop focused on the ongoing collaboration between GOSUD and SAMOS and addressing the needs of the research and operational community for highquality underway oceanographic and meteorological observations from ships. The SAMOS initiative is working to improve access ...

  14. An Inquiry into Perceived Autonomy Support of Iranian EFL Learners: 2nd, 3rd and 4th Grade University Students

    Husain Abdulhay

    2015-01-01

    Gaining an insight into Iranian EFL learning environment is increasingly felt, consonant with dissociation from the traditional and spoon-feeding rituals of Iranian indigenous teaching. To that end, the study tried to scour the grade level differences of 202 students in their perceived autonomy support in the context of Iranian universities. Exposures to autonomy supportive environment were examined in 2nd, 3rd and 4th grade-levels through the administration of Learning Climate Questionnaire ...

  15. CPAPD Held the 9th Joint Conference of Member Organizations and The 2nd Conference of the Board of Directors

    2014-01-01

    <正>On April 4,2014,the Chinese People’s Association for Peace and Disarmament(CPAPD)held the 9th Joint Conference of Member Organizations and the 2nd Conference of the Board of Directors in Beijing.Yan Junqi,Vice-Chairperson of the Standing Committee of the National People’s Congress(NPC):Han Qide,Vice-Chairman of the National Committee of the

  16. 2nd Nordic NJF Seminar on Reindeer Husbandry Research "Reindeer herding and land use management - Nordic perspectives"

    Päivi Soppela

    2015-06-01

    Full Text Available The 2nd NJF Seminar on Reindeer Husbandry Research was held at the Arctic Centre, University of Lapland, Rovaniemi, Finland from 19 to 21 October 2014. The seminar was organised under the framework of Reindeer Husbandry Research Section of NJF (Nordic Association of Agricultural Scientists, established in 2012. Over 100 Nordic and international delegates including researchers, managers, educators, students and reindeer herders participated in the seminar.

  17. Digital rectal examination and transrectal ultrasonography in staging of rectal cancer

    Rafaelsen, Søren Rafael; Kronborg, Ole; Fenger, Claus

    1994-01-01

    Staging of rectal carcinoma before surgical treatment was performed in a prospective blind study, comparing digital rectal exploration and transrectal linear ultrasonography (TRUS) with the resulting pathological examination. TRUS underestimated depth of penetration in 3 of 33 patients and overes...... surgery for cure....

  18. Emotional and Behavioral Disorders in 1.5th Generation, 2nd Generation Immigrant Children, and Foreign Adoptees.

    Tan, Tony Xing

    2016-10-01

    Existing theories (e.g., acculturative stress theory) cannot adequately explain why mental disorders in immigrants are less prevalent than in non-immigrants. In this paper, the culture-gene co-evolutionary theory of mental disorders was utilized to generate a novel hypothesis that connection to heritage culture reduces the risk for mental disorders in immigrant children. Four groups of children aged 2-17 years were identified from the 2007 United States National Survey of Children's Health: 1.5th generation immigrant children (n = 1378), 2nd generation immigrant children (n = 4194), foreign adoptees (n = 270), and non-immigrant children (n = 54,877). The 1.5th generation immigrant children's connection to their heritage culture is stronger than or similar to the 2nd generation immigrants, while the foreign adoptees have little connection to their birth culture. Controlling for age, sex, family type and SES, the odds for having ADD/ADHD, Conduct Disorder, Anxiety Disorder, and Depression diagnosis were the lowest for the 1.5th generation immigrant children, followed by the 2nd generation immigrant children and the foreign adoptees. The foreign adoptees and non-adopted children were similar in the odds of having these disorders. Connection to heritage culture might be the underlying mechanism that explained recent immigrants' lower rates of mental disorders. PMID:26972324

  19. White Paper Summary of 2nd ASTM International Workshop on Hydrides in Zirconium Alloy Cladding

    Sindelar, R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Louthan, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); PNNL, B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-05-29

    This white paper recommends that ASTM International develop standards to address the potential impact of hydrides on the long term performance of irradiated zirconium alloys. The need for such standards was apparent during the 2nd ASTM International Workshop on Hydrides in Zirconium Alloy Cladding and Assembly Components, sponsored by ASTM International Committee C26.13 and held on June 10-12, 2014, in Jackson, Wyoming. The potentially adverse impacts of hydrogen and hydrides on the long term performance of irradiated zirconium-alloy cladding on used fuel were shown to depend on multiple factors such as alloy chemistry and processing, irradiation and post irradiation history, residual and applied stresses and stress states, and the service environment. These factors determine the hydrogen content and hydride morphology in the alloy, which, in turn, influence the response of the alloy to the thermo-mechanical conditions imposed (and anticipated) during storage, transport and disposal of used nuclear fuel. Workshop presentations and discussions showed that although hydrogen/hydride induced degradation of zirconium alloys may be of concern, the potential for occurrence and the extent of anticipated degradation vary throughout the nuclear industry because of the variations in hydrogen content, hydride morphology, alloy chemistry and irradiation conditions. The tools and techniques used to characterize hydrides and hydride morphologies and their impacts on material performance also vary. Such variations make site-to-site comparisons of test results and observations difficult. There is no consensus that a single material or system characteristic (e.g., reactor type, burnup, hydrogen content, end-of life stress, alloy type, drying temperature, etc.) is an effective predictor of material response during long term storage or of performance after long term storage. Multi-variable correlations made for one alloy may not represent the behavior of another alloy exposed to

  20. PREFACE: 1st-2nd Young Researchers Meetings in Rome - Proceedings

    YRMR Organizing Committee; Cannuccia, E.; Mazzaferro, L.; Migliaccio, M.; Pietrobon, D.; Stellato, F.; Veneziani, M.

    2011-03-01

    Students in science, particularly in physics, face a fascinating and challenging future. Scientists have proposed very interesting theories, which describe the microscopic and macroscopic world fairly well, trying to match the quantum regime with cosmological scales. Between the extremes of this scenario, biological phenomena in all their complexity take place, challenging the laws we observe in the atomic and sub-atomic world. More and more accurate and complex experiments have been devised and these are now going to test the paradigms of physics. Notable experiments include: the Large Hadronic Collider (LHC), which is going to shed light on the physics of the Standard Model of Particles and its extensions; the Planck-Herschel satellites, which target a very precise measurement of the properties of our Universe; and the Free Electron Lasers facilities, which produce high-brilliance, ultrafast X-ray pulses, allowing the investigation of the fundamental processes of solid state physics, chemistry, and biology. These projects are the result of huge collaborations spread across the world, involving scientists belonging to different and complementary research fields: physicists, chemists, biologists and others, keen to make the best of these extraordinary laboratories. Even though each branch of science is experiencing a process of growing specialization, it is very important to keep an eye on the global picture, remaining aware of the deep interconnections between inherent fields. This is even more crucial for students who are beginning their research careers. These considerations motivated PhD students and young post-docs connected to the Roman scientific research area to organize a conference, to establish the background and the network for interactions and collaborations. This resulted in the 1st and 2nd Young Researchers Meetings in Rome (http://ryrm.roma2.infn.it), one day conferences aimed primarily at graduate students and post-docs, working in physics in Italy

  1. Archaeometric study of glass beads from the 2nd century BC cemetery of Numantia

    García Heras, Manuel

    2003-06-01

    Full Text Available Recent archaeologícalf ieldwork undertaken in the Celtiberian cremation necropolis of Numantia (Soria, Spain has provided a group of glass beads from the 2nd century BC. Such glass beads were part, together with other metallic and ceramic items, of the offerings deposited with the dead. They are ring-shaped in typology and deep-blue, amber, or semitransparent white in colour. This paper reports results derived from the chemical and microstructural characterization carried out on a representative sample set of this group of beads. The main goal of the research was to find out about their production technology to explore their probable provenance. In addítion, corrosion mechanisms were also assessed to determine the influence of crematíon on the beads' structure. The resulting data suggest that these blue and amber beads were made using soda-lime silicate glass, whereas semi-transparent white ones were manufactured from alumino-silicate glass. It has also determined that some transition metal oxides were used as chromophores, as well as lead oxide for decoration.

    La reciente excavación de la necrópolis celtibérica de Numancia (Garray, Soria ha permitido recuperar un conjunto de cuentas de vidrio del siglo II a.C. Las cuentas, junto con otros objetos de metaly cerámica, formaban parte de las ofrendas depositadas con el difunto, siendo de tipología anular y coloreadas en azul oscuro, ambar y blanco semitransparente. Este trabajo presenta los resultados obtenidos en la caracterización química y microestructural de una muestra representativa de este conjunto. El objetivo principal de la investigación consistió en recabar información sobre su tecnología de manufactura y evaluar su posible procedencia. Asimismo, también se investigaron sus mecanismos de corrosión para determinar si la cremación había inducido cambios en su estructura. Los resultados indican que las cuentas azules y ámbar se realizaron con vidrio de silicato s

  2. Importance of Preoperative Rectal Ultrasound and CT in Rectal Tumors

    Introduction: The reason of high mortality of colorectal carcinoma is above all the fact, that majority of diseases are detected in progressive stage. Radical change in this unfavorable mortality rate can be achieved only by targeted search for early stages of the disease. Early diagnostics consists in rectoscopy and colonoscopy. Regarding X-ray methods it is X-ray irigography. Regarding CT examinations it is CT irigography, virtual colonoscopy. Another examination can be USG examination of abdomen and endo sonographic examination of rectum. Materials and methods: In the period from June 2006 to December 2010, in 60 patients out of the total number 106 examined patients, tumorous affection of rectum CT examination of pelvis and abdomen separately or pelvisand abdomen at one session was made in 3186 patients. In 115 patients we discovered malign tumorous illness of colon. Metastatic affection in the form of distant metastases was proven n 63 patients. 403 patients had CT irigography examination. In 77 out of them we diagnosed colon carcinoma. CT colonoscopy did not discover in our group of 30 patients examined the presence of colon carcinoma. Results: In the group of 60 patients who were diagnosed rectal carcinoma, in 29 patients expansive infiltrative affection was evaluated in endorectal sonography, histologically confirmed in 28 patients - 96,5 %, expansive affection in 41 patients with histological verification in 100 %. With CT we diagnosed 52 expansive tumorous processes, histologically confirmed in 47 patients - 90,38 %. In 63 patients expansive infiltrative process was evaluated, histologically confirmed in 52 patients 82,53 %. In total of 115 examinations there was conformance with histological examination in 99 patients - 86,08 %. In CT irigography we diagnosed colon tumour in 77 patients. Expansive growth was evaluated in 40 patients, histologically confirmed in 37 patients - 92,5 %. Expansive infiltrative expansion was evaluated in 37 patients, with

  3. Preoperative chemoradiation therapy for lower rectal cancer

    Murotani, Masahiro; Tsujinaka, Toshimasa; Takami, Motohisa [Toyonaka Municipal Hospital, Osaka (Japan)] [and others

    1996-09-01

    To identify appropriate candidates with rectal cancer for preoperative chemoradiation therapy, the local recurrence rate and clinicopathological characteristics of 232 patients with rectal cancer undergoing curative resection in our department were investigated. The local recurrence rates were 3.8%, 10.8% and 16.5% in the Rs, Ra and Rb lesions, respectively. Regarding lower (Rb) rectal cancer, depth of lesion (>a{sub 1}) and nodal metastasis consisted of high factors for local recurrence. Basing on these results, entery criteria for preoperative chemoradiation therapy were established, and concurrent chemoradiation therapy with fluorouracil and cisplatin was delivered preoperatively in 9 primary cases of locally advanced rectal cancer and 3 cases with local recurrence. A partial response was obtained in 7 of 12 cases with a response rate of 58%, size-reduction of the distant metastatic lesions was found in 2 cases, and clinical symptoms were improved in all cases. The histological responses of the 6 resected cases were Grade 2 in 2 cases and Grade 1b in 4 cases. The toxicities of this chemoradiation regimen were well tolerable. As a postoperative complication, infection of the perineal wound was most frequent. Preoperative chemoradiation therapy with the present regimen would be a useful adjuvant treatment for advanced lower rectal cancer. (author)

  4. Ethnicity, Confession and Intercultural Dialogue at the European Union’s East Border

    Brie, Mircea; Horga, Ioan; Şipoş, Sorin

    2011-01-01

    This present volume contains the papers of the international conference Ethnicity, Confession and Intercultural Dialogue at the European Union’s East Border, held in Oradea between 2nd-5th of June 2011, organized by Institute for Euroregional Studies Oradea-Debrecen, University of Oradea and Department of International Relations and European Studies, with the support of the European Commission and Bihor County Council.This volume is funded by the project of Action Jean Monnet Programme of the...

  5. Only Half of Rectal Cancer Patients Get Recommended Treatment

    ... nlm.nih.gov/medlineplus/news/fullstory_158339.html Only Half of Rectal Cancer Patients Get Recommended Treatment: ... therapy for rectal cancer in the United States, only slightly more than half of patients receive it, ...

  6. Preoperative staging of rectal cancer.

    Smith, Neil; Brown, Gina

    2008-01-01

    Detailed preoperative staging using high resolution magnetic resonance imaging (MRI) enables the selection of patients that require preoperative therapy for tumour regression. This information can be used to instigate neoadjuvant therapy in those patients with poor prognostic features prior to disturbing the tumour bed and potentially disseminating disease. The design of trials incorporating MR assessment of prognostic factors prior to therapy has been found to be of value in assessing treatment modalities and outcomes that are targeted to these preoperative prognostic subgroups and in providing a quantifiable assessment of the efficacy of particular chemoradiation treatment protocols by comparing pre-treatment MR staging with post therapy histology assessment. At present, we are focused on achieving clear surgical margins of excision (CRM) to avoid local recurrence. We recommend that all patients with rectal cancer should undergo pre-operative MRI staging. Of these, about half will have good prognosis features (T1-T3b, N0, EMVI negative, CRM clear) and may safely undergo primary total mesorectal excision. Of the remainder, those with threatened or involved margins will certainly benefit from pre-operative chemoradiotherapy with the aim of downstaging to permit safe surgical excision. In the future, our ability to recognise features predicting distant failure, such as extramural vascular invasion (EMVI) may be used to stratify patients for neo-adjuvant systemic chemotherapy in an effort to prevent distant relapse. The optimal pre-operative treatment regimes for these patients (radiotherapy alone, systemic chemotherapy alone or combination chemo-radiotherapy) is the subject of current and future trials. PMID:17957502

  7. Californium-252 brachytherapy for anal and ano-rectal carcinoma

    Surgery has historically been the standard treatment for anal, ano-rectal and rectal carcinoma but is prone to local or regional failure. Over the past 15 years there has been increasing interest in and success with radiation therapy and combined chemoradiotherapy for treatment of anal and ano-rectal cancers. Cf-252 brachytherapy combined with external beam teletherapy has been investigated for anal and ano-rectal lesions at the Univ. of Kentucky with encouraging results

  8. 2nd Radio and Antenna Days of the Indian Ocean (RADIO 2014)

    2014-10-01

    It was an honor and a great pleasure for all those involved in its organization to welcome the participants to the ''Radio and Antenna Days of the Indian Ocean'' (RADIO 2014) international conference that was held from 7th to 10th April 2014 at the Sugar Beach Resort, Wolmar, Flic-en-Flac, Mauritius. RADIO 2014 is the second of a series of conferences organized in the Indian Ocean region. The aim of the conference is to discuss recent developments, theories and practical applications covering the whole scope of radio-frequency engineering, including radio waves, antennas, propagation, and electromagnetic compatibility. The RADIO international conference emerged following discussions with engineers and scientists from the countries of the Indian Ocean as well as from other parts of the world and a need was felt for the organization of such an event in this region. Following numerous requests, the Island of Mauritius, worldwide known for its white sandy beaches and pleasant tropical atmosphere, was again chosen for the organization of the 2nd RADIO international conference. The conference was organized by the Radio Society, Mauritius and the Local Organizing Committee consisted of scientists from SUPELEC, France, the University of Mauritius, and the University of Technology, Mauritius. We would like to take the opportunity to thank all people, institutions and companies that made the event such a success. We are grateful to our gold sponsors CST and FEKO as well as URSI for their generous support which enabled us to partially support one PhD student and two scientists to attend the conference. We would also like to thank IEEE-APS and URSI for providing technical co-sponsorship. More than hundred and thirty abstracts were submitted to the conference. They were peer-reviewed by an international scientific committee and, based on the reviews, either accepted, eventually after revision, or rejected. RADIO 2014 brought together participants from twenty countries spanning

  9. Development of Hydrologic Characterization Technology of Fault Zones -- Phase I, 2nd Report

    Karasaki, Kenzi; Onishi, Tiemi; Black, Bill; Biraud, Sebastien

    2009-03-31

    This is the year-end report of the 2nd year of the NUMO-LBNL collaborative project: Development of Hydrologic Characterization Technology of Fault Zones under NUMO-DOE/LBNL collaboration agreement, the task description of which can be found in the Appendix 3. Literature survey of published information on the relationship between geologic and hydrologic characteristics of faults was conducted. The survey concluded that it may be possible to classify faults by indicators based on various geometric and geologic attributes that may indirectly relate to the hydrologic property of faults. Analysis of existing information on the Wildcat Fault and its surrounding geology was performed. The Wildcat Fault is thought to be a strike-slip fault with a thrust component that runs along the eastern boundary of the Lawrence Berkeley National Laboratory. It is believed to be part of the Hayward Fault system but is considered inactive. Three trenches were excavated at carefully selected locations mainly based on the information from the past investigative work inside the LBNL property. At least one fault was encountered in all three trenches. Detailed trench mapping was conducted by CRIEPI (Central Research Institute for Electric Power Industries) and LBNL scientists. Some intriguing and puzzling discoveries were made that may contradict with the published work in the past. Predictions are made regarding the hydrologic property of the Wildcat Fault based on the analysis of fault structure. Preliminary conceptual models of the Wildcat Fault were proposed. The Wildcat Fault appears to have multiple splays and some low angled faults may be part of the flower structure. In parallel, surface geophysical investigations were conducted using electrical resistivity survey and seismic reflection profiling along three lines on the north and south of the LBNL site. Because of the steep terrain, it was difficult to find optimum locations for survey lines as it is desirable for them to be as

  10. Development of Hydrologic Characterization Technology of Fault Zones: Phase I, 2nd Report

    This is the year-end report of the 2nd year of the NUMO-LBNL collaborative project: Development of Hydrologic Characterization Technology of Fault Zones under NUMO-DOE/LBNL collaboration agreement, the task description of which can be found in the Appendix 3. Literature survey of published information on the relationship between geologic and hydrologic characteristics of faults was conducted. The survey concluded that it may be possible to classify faults by indicators based on various geometric and geologic attributes that may indirectly relate to the hydrologic property of faults. Analysis of existing information on the Wildcat Fault and its surrounding geology was performed. The Wildcat Fault is thought to be a strike-slip fault with a thrust component that runs along the eastern boundary of the Lawrence Berkeley National Laboratory. It is believed to be part of the Hayward Fault system but is considered inactive. Three trenches were excavated at carefully selected locations mainly based on the information from the past investigative work inside the LBNL property. At least one fault was encountered in all three trenches. Detailed trench mapping was conducted by CRIEPI (Central Research Institute for Electric Power Industries) and LBNL scientists. Some intriguing and puzzling discoveries were made that may contradict with the published work in the past. Predictions are made regarding the hydrologic property of the Wildcat Fault based on the analysis of fault structure. Preliminary conceptual models of the Wildcat Fault were proposed. The Wildcat Fault appears to have multiple splays and some low angled faults may be part of the flower structure. In parallel, surface geophysical investigations were conducted using electrical resistivity survey and seismic reflection profiling along three lines on the north and south of the LBNL site. Because of the steep terrain, it was difficult to find optimum locations for survey lines as it is desirable for them to be as

  11. Masquerading Mycobacterium: Rectal Growth or Tuberculosis?

    Nabajit Choudhury

    2013-01-01

    Full Text Available A 37-year old male presented to us with history of lower abdominal pain for 6 months. His physical examination revealed a rectal mass of approximately 1centimeter. He was investigated for possible rectal growth with sigmoidoscopy and biopsy. The histopathological examination (HPE showed a non-specific chronic inflammation in the tissue from the mass. Another tissue from the mass was sent for polymerase chain reaction (PCR for tuberculosis, which turned out to be positive. The patient was started on standard anti tubercular (ATT regimen and responded completely to the treatment. We discuss the patient and review some of the available literature on the topic and discuss the issue of considering a diagnosis of tuberculosis in cases with rectal mass specially when it has become a major public health issue with increasing number of HIV (Human Immunodeficiency Virus infected patients.

  12. Anorectal function orientated surgery for rectal prolapse

    Until quite recently, rectal prolapse was regarded as being a simple condition to treat. Surgical control of the prolapse was largely regarded as a successful outcome. However, recent detailed clinical assessment indicate that many patients have a rectal prolapse which is successfully controlled by surgical operation, yet suffer severe symptoms of disordered defecation, which either persists, or develops as a result of operative treatment. Difficulty with rectal evacuation, persistent incontinence and continuing mucus discharge are recognized as important, despite successful repair of the prolapse itself. There are two major theory of the pathology; circumferential intussusception and sliding hernia. However, many other multifarious factors are concomitant with the condition. These factors often need to be balanced against one another. Usually, a single surgical procedure will not be able to solve the problems. Therefore, the choice of treatment tailored for the individual patient. (author)

  13. MRI Findings of Rectal Submucosal Tumors

    Kim, Hon Soul; Kim, Joo Hee; Lim, Joon Seok; Choi, Jin Young; Chung, Yong Eun; Park, Mi Suk; Kim, Myeong Jin; Kim, Ki Whang; Kim, Sang Kyum [Yonsei University Health System, Seoul (Korea, Republic of)

    2011-08-15

    Rectal submucosal lesions encompass a wide variety of benign and malignant tumors involving the rectum. With optical colonoscopy, any mass-like protrusion covered by normal mucosa, whether the underlying process is intramural or extramural in origin, may be reported as a submucosal lesion. Whereas the assessment of submucosal lesions may be limited with performing optical colonoscopy, cross-sectional imaging such as CT, transrectal ultrasonography and MRI allows the evaluation of perirectal tissues and pelvic organs in addition to the entire thickness of the rectum, and so this is advantageous for the assessment of rectal submucosal tumors. Among these, MRI is the best investigative modality for soft tissue characterization. Therefore, knowledge of the MRI features of rectal submucosal tumors can help achieve accurate preoperative diagnoses and facilitate the appropriate management.

  14. Rectal cancer treatment: Improving the picture

    2007-01-01

    Multidisciplinary approach for rectal cancer treatment is currently well defined. Nevertheless, new and promising advances are enriching the portrait. Since the US NIH Consensus in the early 90's some new characters have been added. A bird's-eye view along the last decade shows the main milestones in the development of rectal cancer treatment protocols. New drugs, in combination with radiotherapy are being tested to increase response and tumor control outcomes. However, therapeutic intensity is often associated with toxicity. Thus, innovative strategies are needed to create a better-balanced therapeutic ratio. Molecular targeted therapies and improved technology for delivering radiotherapy respond to the need for accuracy and precision in rectal cancer treatment.

  15. Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention

    Rao, Sheng-Xiang; Zeng, Meng-Su; Xu, Jian-Ming; Qin, Xin-Yu; Chen, Cai-Zhong; Li, Ren-Chen; Hou, Ying-Yong

    2007-01-01

    AIM: To determine the accuracy of high-resolution magnetic resonance imaging (MRI) using phased-array coil for preoperative assessment of T staging and mesorectal fascia infiltration in rectal cancer with rectal distention.

  16. Primary Transanal Management of Rectal Atresia in a Neonate.

    M, Braiek; A, Ksia; I, Krichen; S, Belhassen; K, Maazoun; S, Ben Youssef; N, Kechiche; M, Mekki; A, Nouri

    2016-01-01

    Rectal atresia (RA) with a normal anus is a rare anomaly. We describe a case of rectal atresia in a newborn male presenting with an abdominal distension and failure of passing meconium. The rectal atresia was primarily operated by transanal route. PMID:27123404

  17. Using of modified irrigoscopy in the diagnosis of rectal prolaps and rectal intussusception

    Colonic X-ray findings in 39 patients with rectal prolapse are presented. Of them, 20 and 19 patients were found to have internal and external rectal prolapse, respectively. Studies were conducted by the modified irrigoscopy developed by the State Coloproctology Research Center, Ministry of Health of the Russian Federation, to explore the anatomic and functional status of the rectum and the fundus of the pelvis in patients with impaired defecation. The X-ray sign of circular invagination with oral enterography for external rectal prolapse could show associated changes, including enterocele and sigmocele

  18. Cyclical rectal bleeding in colorectal endometriosis.

    Levitt, M D; Hodby, K J; van Merwyk, A J; Glancy, R J

    1989-12-01

    Three case reports of cyclical rectal bleeding in endometriosis affecting rectum and sigmoid colon emphasize the close relationship between such cyclical bleeding and intestinal endometriosis. The cause of bleeding, however, is still unclear. The predilection of endometriotic deposits for the outer layers of the bowel wall suggests that mucosal involvement is not a prerequisite for rectal bleeding. The frequent absence of identifiable intramural haemorrhage casts doubt on the premise that intestinal endometriotic deposits 'menstruate'. The cause may simply be a transient tear in normal mucosa due to swelling of an underlying endometriotic deposit at the time of menstruation. PMID:2597100

  19. Noise Characteristics of 64-channel 2nd-order DROS Gradiometer System inside a Poorly Magnetically-shielded Room

    Kim, J. M.; Lee, Y. H.; Yu, K. K.; Kim, K.; Kwon, H.; Park, Y. K. [Biosignal Research Center, Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of); Sasada, Ichiro [Dept. of Applied Science for Electronics and Materials, Ktushu University, Fukuoka (Korea, Republic of)

    2006-10-15

    We have developed a second-order double relaxation oscillation SQUID(DROS) gradiometer with a baseline of 35 mm, and constructed a poorly magnetically-shielded room(MSR) with an aluminum layer and permalloy layers for magnetocardiography(MCG). The 2nd-order DROS gradiometer has a noise level of 20 fT/Hz at 1 Hz and 8 fT/Hz at 200 Hz inside the heavily-shielded MSR with a shielding factor of10{sup 3}at 1 Hz and 10{sup 4} - 10{sup 5} at 100 Hz. The poorly-shielded MSR, built of a 12-mm-thick aluminum layer and 4-6 permalloy layers of 0.35 mm thickness, is 2.4 m x 2.4 m x 2.4 m in size, and has a shielding factor of 40 at 1 Hz, 10{sup 4} at 100 Hz. Our 64-channel second-order gradiometer MCG system consists of 64 2nd-order DROS gradiometers, flux-locked loop electronics, and analog signal processors. With the 2nd-order DROS gradiometers and flux-locked loop electronics installed inside the poorly-shielded MSR, and with the analog signal processor installed outside it, the noise level was measured to be 20 fT/Hz at 1 Hz and 8 fT/Hz at 200 Hz on the average even though the MSR door is open. This result leads to a low noise level, low enough to obtain a human MCG at the same level as that measured in the heavily-shielded MSR. However, filters or active shielding is needed fur clear MCG when there is large low-frequency noise from heavy air conditioning or large ac power consumption near the poorly-shielded MSR.

  20. Clinical study on treatment of rectal carcinoma with Chinese herbal medicine and high dose fluorouracil emulsion via rectal infusion.

    王晨光

    1999-01-01

    Objective: To study the clinical significance of rectal infusion of Chinese herbal medicine (CHM) plus high dose fluorouracil emulsion in treating rectal carcinoma. Methods: 86 patients of rectal carcinoma were randomly divided into CHM plus chemotherapy group and single chemotherapy group, and the

  1. Virtual Visit to the ATLAS Control Room by 2nd High School of Eleftherio–Kordelio in Thessaloniki

    2013-01-01

    Our school is the 2nd High School of Eleftherio – Kordelio. It is located at the west suburbs of Thessaloniki in Greece and our students are between 15-17 years old. Thessaloniki is the second largest city in Greece with a port of a major role in trading at the area of South Balkans. During this period of time our students have heard so much about CERN and the great discoveries which have taken place there and they are really keen on visiting and learning many things about it.

  2. Order and disorder in Ca2ND0.90H0.10-A structural and thermal study

    The structure of calcium nitride hydride and its deuterided form has been re-examined at room temperature and studied at high temperature using neutron powder diffraction and thermal analysis. When synthesised at 600 deg. C, a mixture of both ordered and disordered Ca2ND0.90H0.10 phases results. The disordered phase is the minor component and has a primitive rocksalt structure (spacegroup Fm3m) with no ordering of D/N on the anion sites and the ordered phase is best described using the rhombohedral spacegroup R-3m with D and N arranged in alternate layers in (111) planes. This mixture of ordered and disordered phases exists up to 580 deg. C, at which the loss of deuterium yields Ca2ND0.85 with the disappearance of the disordered phase. In the new ordered phase there exists a similar content of vacancies on both anion sites; to achieve this balance, a little N transfers onto the D site, whereas there is no indication of D transferring onto the N-sites. These observations are thought to indicate that the D/N ordering is difficult to achieve with fully occupied anion sites. It has previously been reported that Ca2ND has an ordered cubic cell with alternating D and N sites in the [100] directions ; however, for the samples studied herein, there were clearly two coexisting phases with apparent broadening/splitting of the primitive peaks but not for the ordered peaks. The rhombohedral phase was in fact metrically cubic; however, all the observed peaks were consistent with the rhombohedral unit cell with no peaks requiring the larger ordered cubic unit cell to be utilised. Furthermore this rhombohedral cell displays the same form of N-D ordering as the Sr and Ba analogues, which are metrically rhombohedral. - Graphical abstract: Ca2ND0.90H0.10 forms a mixture of ordered and disordered phases when synthesised at 600 deg. C. The ordered phase disappears at high temperature upon release of structural deuterium/hydrogen, leaving a single, partially disordered phase. Research

  3. Underlying anatomy for CTV contouring and lymphatic drainage in rectal cancer radiation therapy.

    Arcangeli, Stefano; Valentini, Vincenzo; Nori, Stefania L; Fares, Claudia; Dinapoli, Nicola; Gambacorta, Maria Antonierrta

    2003-01-01

    Despite the low local recurrence rate that can be achieved by adequate surgery (total mesorectal excision--TME), radiation therapy was shown to play a significant role in reducing this risk. The widespread use of TME in many European Centers has introduced a new terminology and the need to identify the area at major risk for local failure using this surgical procedure. In the surgical series where extended extra-mesorectal surgery was performed, the role of lymphatic spread was evidenced, especially for low rectal cancer, through the pelvic parietal fascia and lateral pelvic spaces. The aim of this study was to better define some anatomic concepts and the main risk factors which impact on CTV contouring and field conformation in rectal cancer treatment. This information helps formulating guidelines for CTV contouring in daily radiotherapy practice, in order to define the best therapy, according to the tumor stage and location. PMID:15018321

  4. Hemangioma colorretal Colon rectal hemangioma

    João Batista Pinheiro Barreto

    2007-06-01

    Full Text Available O hemangioma colorretal (HCR é uma lesão vascular benigna rara, com manifestação clínica geralmente entre 5 e 25 anos de idade. Faz parte do diagnóstico diferencial das causas de hemorragia digestiva baixa, sendo confundido, na maioria das vezes, com entidades mais comuns, como hemorróidas e doenças inflamatórias intestinais. O retardo do diagnóstico ocorre freqüentemente devido ao desconhecimento da doença, com taxas de mortalidade alcançando 40 a 50% na presença de sangramento importante. O caso relatado é de uma paciente de 17 anos de idade, admitida no Serviço de Colo-proctologia do Hospital Universitário - HUUFMA, em setembro de 2005, com anemia e sangramento retal, desde a infância, de forma intermitente e não dolorosa. Apresentado sua história clínica e propedêutica diagnóstica, realizada por meio de exames laboratoriais, endoscopia digestiva alta, colonoscopia e arteriografia de mesentéricas e ilíacas internas. O tratamento cirúrgico realizado foi retossigmoidectomia convencional com anastomose colorretal baixa, com boa evolução pós-operatória, tendo o exame histopatológico da peça cirúrgica ressecada, confirmado o diagnostico.The colon and rectum hemangioma is a rare benign vascular lesion, with clinical features usually between 5 and 25 years of age. It is included in the differential diagnose of the lower digestive bleeding causes, and has been frequently misdiagnosed with other more common entities, like hemorrhoids and bowel inflammatory disease. The late diagnose occurs usually because of the rarity of the disease, with mortality rates reaching 40 to 50% in presence of severe bleeding. We report a case of a 17 years old girl who was admitted at the Coloproctology Service of the Academic Hospital - HUUFMA, in September 2005, with anemia and intermittent rectal bleeding since childhood. Laboratorial findings included laboratorial exams, GI endoscopy, colonoscopy and arteriography of mesenteric and

  5. Rectal motility after sacral nerve stimulation for faecal incontinence

    Michelsen, H B; Worsøe, J; Krogh, K;

    2010-01-01

    Sacral nerve stimulation (SNS) is effective against faecal incontinence, but the mode of action is obscure. The aim of this study was to describe the effects of SNS on fasting and postprandial rectal motility. Sixteen patients, 14 women age 33-73 (mean 58), with faecal incontinence of various...... contractions, total time with cyclic rectal contractions, the number of aborally and orally propagating contractions, the number of anal sampling reflexes or rectal wall tension during contractions. Postprandial changes in rectal tone were significantly reduced during SNS (P < 0.02). Before SNS, median rectal...

  6. Expression and role of Tie-2 in rectal carcinoma

    2010-01-01

    Objective To investigate the expression of Tie-2 in rectal carcinoma and its relationship with invasion and metastasis in rectal carcinoma.Materials S-P immunohistochemical assay was used to detect the expression of Tie-2 in 40 cases of rectal carcinoma and 10 cases of normal rectal tissues.Results Tie-2 was mainly localized in the cytoplasm and nucleus of vascular endothelial cells in cancerous tissues and partly in the cytoplasm of some cancerous cells.The expression of Tie-2 in rectal carcinoma was signi...

  7. FOREWORD: 2nd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2012)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2012-09-01

    Conference logo This volume of Journal of Physics: Conference Series is dedicated to the scientific contributions presented during the 2nd International Workshop on New Computational Methods for Inverse Problems, (NCMIP 2012). This workshop took place at Ecole Normale Supérieure de Cachan, in Cachan, France, on 15 May 2012, at the initiative of Institut Farman. The first edition of NCMIP also took place in Cachan, France, within the scope of the ValueTools Conference, in May 2011 (http://www.ncmip.org/2011/). The NCMIP Workshop focused on recent advances in the resolution of inverse problems. Indeed inverse problems appear in numerous scientific areas such as geophysics, biological and medical imaging, material and structure characterization, electrical, mechanical and civil engineering, and finance. The resolution of inverse problems consists of estimating the parameters of the observed system or structure from data collected by an instrumental sensing or imaging device. Its success firstly requires the collection of relevant observation data. It also requires accurate models describing the physical interactions between the instrumental device and the observed system, as well as the intrinsic properties of the solution itself. Finally, it requires the design of robust, accurate and efficient inversion algorithms. Advanced sensor arrays and imaging devices provide high rate and high volume data; in this context, the efficient resolution of the inverse problem requires the joint development of new models and inversion methods, taking computational and implementation aspects into account. During this one-day workshop, researchers had the opportunity to bring to light and share new techniques and results in the field of inverse problems. The topics of the workshop were: algorithms and computational aspects of inversion, Bayesian estimation, kernel methods, learning methods, convex optimization, free discontinuity problems, metamodels, proper orthogonal decomposition

  8. Sustainable development - a role for nuclear power? 2nd scientific forum

    The 2nd Scientific Forum of the International Atomic Energy Agency (IAEA) was held during the 43rd General Conference. This paper summarizes the deliberations of the two-day Forum. The definition of 'sustainable development' of the 1987 Bruntland Commission - 'development that meets the needs of the present without compromising the ability of future generations to meet their own needs' - provided the background for the Forum's debate whether and how nuclear power could contribute to sustainable energy development. The framework for this debate comprises different perspectives on economic, energy, environmental, and political considerations. Nuclear power, along with all energy generating systems, should be judged on these considerations using a common set of criteria (e.g., emission levels, economics, public safety, wastes, and risks). First and foremost, there is a growing political concern over the possible adverse impact of increasing emissions of greenhouse gases from fossil fuel combustion. However, there is debate as to whether this would have any material impact on the predominantly economic criteria currently used to make investment decisions on energy production. According to the views expressed, the level of safety of existing nuclear power plants is no longer a major concern - a view not yet fully shared by the general public. The need to maintain the highest standards of safety in operation remains, especially under the mounting pressure of competitiveness in deregulated and liberalized energy markets. The industry must continuously reinforce a strong safety culture among reactor designers, builders, and operators. Furthermore, a convincing case for safety will have to be made for any new reactor designs. Of greater concern to the public and politicians are the issues of radioactive waste and proliferation of nuclear weapons. There is a consensus among technical experts that radioactive wastes from nuclear power can be disposed of safely and

  9. Brain order disorder 2nd group report of f-EEG

    Lalonde, Francois; Gogtay, Nitin; Giedd, Jay; Vydelingum, Nadarajen; Brown, David; Tran, Binh Q.; Hsu, Charles; Hsu, Ming-Kai; Cha, Jae; Jenkins, Jeffrey; Ma, Lien; Willey, Jefferson; Wu, Jerry; Oh, Kenneth; Landa, Joseph; Lin, C. T.; Jung, T. P.; Makeig, Scott; Morabito, Carlo Francesco; Moon, Qyu; Yamakawa, Takeshi; Lee, Soo-Young; Lee, Jong-Hwan; Szu, Harold H.; Kaur, Balvinder; Byrd, Kenneth; Dang, Karen; Krzywicki, Alan; Familoni, Babajide O.; Larson, Louis; Harkrider, Susan; Krapels, Keith A.; Dai, Liyi

    2014-05-01

    Since the Brain Order Disorder (BOD) group reported on a high density Electroencephalogram (EEG) to capture the neuronal information using EEG to wirelessly interface with a Smartphone [1,2], a larger BOD group has been assembled, including the Obama BRAIN program, CUA Brain Computer Interface Lab and the UCSD Swartz Computational Neuroscience Center. We can implement the pair-electrodes correlation functions in order to operate in a real time daily environment, which is of the computation complexity of O(N3) for N=102~3 known as functional f-EEG. The daily monitoring requires two areas of focus. Area #(1) to quantify the neuronal information flow under arbitrary daily stimuli-response sources. Approach to #1: (i) We have asserted that the sources contained in the EEG signals may be discovered by an unsupervised learning neural network called blind sources separation (BSS) of independent entropy components, based on the irreversible Boltzmann cellular thermodynamics(ΔS brain at constant temperature, we can solve the minimum of Helmholtz free energy (H = E - TS) by computing BSS, and then their pairwise-entropy source correlation function. (i) Although the entropy itself is not the information per se, but the concurrence of the entropy sources is the information flow as a functional-EEG, sketched in this 2nd BOD report. Area #(2) applying EEG bio-feedback will improve collective decision making (TBD). Approach to #2: We introduce a novel performance quality metrics, in terms of the throughput rate of faster (Δt) & more accurate (ΔA) decision making, which applies to individual, as well as team brain dynamics. Following Nobel Laureate Daniel Kahnmen's novel "Thinking fast and slow", through the brainwave biofeedback we can first identify an individual's "anchored cognitive bias sources". This is done in order to remove the biases by means of individually tailored pre-processing. Then the training effectiveness can be maximized by the collective product Δt *

  10. The Ukrainian community of Western Siberia: specific features of formation and development in the 2nd half of the 19th – early 20th century

    Vladimir N. Shaidurov

    2016-03-01

    Full Text Available The agrarian crisis in the European part of the Russian Empire in the middle of the 20th century seriously impeded agricultural progress. Agrarian overpopulation and peasants deprived of land in the course of the peasant reform of 1861 further aggravated the negative situation in the governorates of Central Russia, Belarus, and left-bank Ukraine. These factors provided fertile soil for migratory sentiments among peasants. It was resettlement in vacant lands in the Asiatic Russia and North Caucasus, which allowed most of them to preserve their homesteads. In the 2nd half of the 19th – early 20th century, Ukrainian peasants were actively engaged in the migration movement which was supported by the state. One of the main placement areas became Western Siberia where a large Ukrainian peasant community was formed. The history of research on the Ukrainian community in Western Siberia is fragmentary, as many aspects remain unstudied. Hence, the article focuses on the following questions: causes of the Ukrainian migration to the border lands of the Russian Empire; stages in the migration; main areas where Ukrainians resided in Siberia; population dynamics of the Ukrainian community; adaptation patterns specific for Ukrainian migrants in their new places of residence; their role in the economic life of Siberia in the early 20th century. This article utilizes primary data from the All-Russian Agricultural and Land Census of 1917, which have been introduced for scientific use for the first time. As the methodological basis, the study draws on the system approach combining regional, neo-imperial and comparative principles.

  11. Endorectal Ultrasonography of Rectal Tumours

    Nonner, J; Waage, Jo Erling Riise; Hermsen, PEA;

    2015-01-01

    This book is intended as the equivalent of the Swiss Army knife for all members of colorectal cancer (CRC) multidisciplinary teams and those training in the fields of CRC management. It describes how to organize the team and explains the basic principles within the different disciplines involved in......-specific chapter will be approachable for team members from other specialties or professions, thereby facilitating an effective interdisciplinary approach to teamwork. The authors include leading European doctors and scientists who have influenced the development of the multidisciplinary team concept as well as...

  12. Comfort During Digital Rectal Examination - Patient Preference*

    Dziki Łukasz

    2015-09-01

    Full Text Available The sex and age of the physician performing the digital rectal examination (DRE procedure is one of the parameters influencing patients’ comfort. It is postulated that the stress related to DRE during admission to the surgical ward may affect the compliance.

  13. Preoperative chemoradiotherapy for advanced lower rectal carcinoma

    Preoperative chemoradiotherapy in combination with radiation of 30 Gy and chemotherapy with oral uracil-tegafur for 14 patients with advanced lower rectal carcinoma was performed. Tumors were located at RaRb in 5 cases, RbRa in 2, Rb in 3, and RbP in 4 with a mean diameter of 3.8 cm. Preoperative lymphnodes were diagnosed as cN0 in 8 cases, cN1 (metastases of perirectal nodes) in 4, cN1 (perirectal and along superior rectal artery nodes) in 1, and cN3 (perirectal and lateral nodes) in 1. Efficacy for primary carcinomas was evaluated as Partial Response in 9 cases, Stable Disease in 5 and perirectal nodes were down-sized in 4 without down-sizing of either along superior rectal artery nodes or lateral nodes. Margins of primary carcinomas to anal verge were prolonged in 7 cases with a mean prolongation of 0.81 cm. Autonomic nerve-preserving resections with lymphadenectomy of perirectal and along superior rectal artery nodes were performed. Histopathologically efficacy for primary tumors was diagnosed to as not effective in 9 cases, partially effective in 5, and all lymphnodes were combined with necroses and fibrosis. Preoperative chemoradiotherapy is safe for preserving autonomic nerves and serves to preserve the sphincter. A forthcoming study with more appropriate radiation, chemotherapy and lymphadenectomy is being considered. (author)

  14. Effect of rectal distension on abdominal girth.

    Marino, B; Ogliari, C; Basilisco, G

    2004-08-01

    It has been postulated that a viscerosomatic reflex activated by gut distension and inhibiting abdominal wall muscle tone may be one of the mechanisms underlying functional abdominal distension. Any demonstration of such a reflex has to take into account the fact that gut distension may increase abdominal girth as a result of volume displacement. As biomechanical and sensory rectal responses vary at different rates of rectal distension, we hypothesized that different rates of rectal distension might reveal different changes in abdominal girth. Abdominal girth was continuously recorded in 14 healthy subjects using a previously validated extensometer. The rectal distensions were made in a randomized order at rates of 100 mL min(-1) or 10 mL min(-1) up to 150 mL, and sham distensions were used as controls. An increase in abdominal girth was observed at the end of both distensions (P

  15. Current management of locally recurrent rectal cancer

    Nielsen, Mette Bak; Laurberg, Søren; Holm, Thorbjörn

    2011-01-01

    ABSTRACT Objective: A review of the literature was undertaken to provide an overview of the surgical management of locally recurrent rectal cancer (LRRC) after the introduction of total mesorectal excision (TME). Method: A systematic literature search was undertaken using PubMed, Embase, Web of...

  16. Ergotamine-induced solitary rectal ulcer.

    Shpilberg, O; Ehrenfeld, M.; Abramowich, D.; Samra, Y.; Bat, L.

    1990-01-01

    A rare case of ergotamine-induced solitary rectal ulcer is described in a 41 year old woman who used high doses of ergotamine tartrate-containing suppositories for severe migraine headaches. Complete recovery of the ulcer was noticed after cessation of treatment with the suppositories. The relevant literature is discussed.

  17. Management of synchronous rectal and prostate cancer.

    Kavanagh, D O

    2012-11-01

    Although well described, there is limited published data related to management on the coexistence of prostate and rectal cancer. The aim of this study was to describe a single institution\\'s experience with this and propose a treatment algorithm based on the best available evidence.

  18. Proceedings of the 2nd JAERI symposium on HTGR technologies October 21 ∼ 23, 1992, Oarai, Japan

    The Japan Atomic Energy Research Institute (JAERI) held the 2nd JAERI Symposium on HTGR Technologies on October 21 to 23, 1992, at Oarai Park Hotel at Oarai-machi, Ibaraki-ken, Japan, with support of International Atomic Energy Agency (IAEA), Science and Technology Agency of Japan and the Atomic Energy Society of Japan on the occasion that the construction of the High Temperature Engineering Test Reactor (HTTR), which is the first high temperature gas-cooled reactor (HTGR) in Japan, is now being proceeded smoothly. In this symposium, the worldwide present status of research and development (R and D) of the HTGRs and the future perspectives of the HTGR development were discussed with 47 papers including 3 invited lectures, focusing on the present status of HTGR projects and perspectives of HTGR Development, Safety, Operation Experience, Fuel and Heat Utilization. A panel discussion was also organized on how the HTGRs can contribute to the preservation of global environment. About 280 participants attended the symposium from Japan, Bangladesh, Germany, France, Indonesia, People's Republic of China, Poland, Russia, Switzerland, United Kingdom, United States of America, Venezuela and the IAEA. This paper was edited as the proceedings of the 2nd JAERI Symposium on HTGR Technologies, collecting the 47 papers presented in the oral and poster sessions along with 11 panel exhibitions on the results of research and development associated to the HTTR. (author)

  19. Surface-emitting quantum cascade laser with 2nd-order metal-semiconductor gratings for single-lobe emission

    Boyle, C.; Sigler, C.; Kirch, J. D.; Lindberg, D.; Earles, T.; Botez, D.; Mawst, L. J.

    2016-03-01

    Grating-coupled, surface-emitting (GCSE) quantum-cascade lasers (QCLs) are demonstrated with high-power, single-lobe surface emission. A 2nd-order Au-semiconductor distributed-feedback (DFB)/ distributed-Bragg-reflector (DBR) grating is used for feedback and out-coupling. The DFB and DBR grating regions are 2.55 mm- and 1.28 mm-long, respectively, for a total grating length of 5.1 mm. The lasers are designed to operate in a symmetric longitudinal mode by causing resonant coupling of the guided optical mode to the antisymmetric surface-plasmon modes of the 2nd-order metal/semiconductor grating. In turn, the antisymmetric longitudinal modes are strongly absorbed by the metal in the grating, causing the symmetric longitudinal mode to be favored to lase, which produces a single lobe beam over a grating duty-cycle range of 36-41 %. Simulations indicate that the symmetric mode is always favored to lase, independent of the random phase of residual reflections from the device's cleaved ends. Peak pulsed output powers of ~ 0.4 W were measured with single-lobe, single-mode operation near 4.75 μm.

  20. Synthetic CO, H2 and HI surveys of the Galactic 2nd Quadrant, and the properties of molecular gas

    Duarte-Cabral, A; Dobbs, C L; Mottram, J C; Gibson, S J; Brunt, C M; Douglas, K A

    2014-01-01

    We present CO, H2, HI and HISA distributions from a set of simulations of grand design spirals including stellar feedback, self-gravity, heating and cooling. We replicate the emission of the 2nd Galactic Quadrant by placing the observer inside the modelled galaxies and post process the simulations using a radiative transfer code, so as to create synthetic observations. We compare the synthetic datacubes to observations of the 2nd Quadrant of the Milky Way to test the ability of the current models to reproduce the basic chemistry of the Galactic ISM, as well as to test how sensitive such galaxy models are to different recipes of chemistry and/or feedback. We find that models which include feedback and self-gravity can reproduce the production of CO with respect to H2 as observed in our Galaxy, as well as the distribution of the material perpendicular to the Galactic plane. While changes in the chemistry/feedback recipes do not have a huge impact on the statistical properties of the chemistry in the simulated g...

  1. Numerical stability of 2nd order Runge-Kutta integration algorithms for use in particle-in-cell codes

    An essential ingredient of particle-in-cell (PIC) codes is a numerically accurate and stable integration scheme for the particle equations of motion. Such a scheme is the well known time-centered leapfrog (LF) method accurate to 2nd order with respect to the timestep Δt. However, this scheme can only be used for forces independent of velocity unless a simple enough implicit implementation is possible. The LF scheme is therefore inapplicable in Monte-Carlo treatments of particle collisions and/or interactions with radio-frequency fields. We examine here the suitability of the 2nd order Runge-Kutta (RK) method. We find that the basic RK scheme is numerically unstable, but that conditional stability can be attained by an implementation which preserves phase space area. Examples are presented to illustrate the performance of the RK schemes. We compare analytic and computed electron orbits in a traveling nonlinear wave and also show self-consistent PIC simulations describing plasma flow in the vicinity of a lower hybrid antenna. (author)

  2. Time resolved 2nd harmonic generation at LaAlO3/SrTiO3 Interfaces

    Adhikari, Sanjay; Eom, Chang-Beom; Ryu, Sangwoo; Cen, Cheng

    2014-03-01

    Ultrafast spectroscopy can produce information of carrier/lattice dynamics, which is especially valuable for understanding phase transitions at LaAlO3/SrTiO3 interfaces. LaAlO3 (LAO) and SrTiO3 (STO) are both associated with wide band gap, which allows deep penetration of commonly used laser wavelengths and therefore usually leads to overwhelming bulk signal background. Here we report a time resolved study of a 2nd harmonic generation (SHG) signal resulting from impulsive below-the-band-gap optical pumping. The nonlinear nature of the signal enables us to probe the interface directly. Output of a home built Ti:Sapphire laser and BBO crystal were used to generate 30fs pulses of two colors (405nm and 810nm). The 405nm pulse was used to pump the LAO/STO interfaces, while 2nd harmonics of the 810nm pulse generated at the interfaces was probed as a function of the time delay. Signals from samples with varying LAO thicknesses clearly correlates to the metal-insulator transition. Distinct time dependent signals were observed at LAO/STO interfaces grown on different substrates. Experiments performed at different optical polarization geometries, interface electric fields and temperatures allow us to paint a clearer picture of the novel oxide heterostructures under investigation.

  3. Cosmology and Particle Astrophysics (2nd edn) and Extragalactic Astronomy and Cosmology: An Introduction

    Trimble, Virginia [Department of Physics and Astronomy, University of California-Irvine, CA 92697-4575 (United States); Las Cumbres Global Telescope Network, Goleta, CA 93117 (United States)

    2007-05-07

    a while to find the bits you want. The index lists neither lambda nor the cosmological constant, and inflation is said to appear on pp 307-412. The chapters are of equal length, in traditional textbook fashion. Neither volume has much to say about issues that are currently 'hot'-the importance of extra dimensions, fine tuning of cosmological parameters, possible evidence for cosmic geometry different from the simplest. Discussions of such things will, of course, date a textbook quickly. On the other hand, they are often the items that physics (etc) students will have heard about in colloquia and would like to have clarified. Names appear only as eponyms, from Altarelli Parisi evolution (which is not on the page to which B and G's index refers you) to the Zeeman effect, which is where PS's index says it is. Can I imagine using either of these as texts? Definitely yes for PS, since it is a possible fit to an astrophysics course that UCI offers as a 'vocabulary builder' for students coming out of mainstream physics (and for which we have yet to find an entirely suitable text). We are contemplating a faculty hire or two in astro-particle physics, in which case B and G might well be a good fit to a seminar for students beginning work in that area. If I were asked to teach the course, however, I would probably want an instructor's solution manual for the text problems. One may well exist, though the book does not mention it. Using PS, you will have to make up your own problems (which you can then reasonably be expected to be able to work without help). (Book review of Cosmology and Particle Astrophysics (2nd edn), Lars Bergstroem and Ariel Goobar, 2006 Berlin: Springer and Worthing: Praxis, ISBN 978-3-540-33174-2 and Extragalactic Astronomy and Cosmology: An Introduction, Peter Schneider, 2006 Berlin: Springer, ISBN 978-3-540-33174-2)

  4. PREFACE: 2nd International Conference on Particle Physics in memoriam Engin Arık and her Colleagues

    Çetin, Serkant Ali; Jenni, Peter; Erkcan Özcan, Veysi; Nefer Şenoğuz, Vedat

    2012-02-01

    The 2nd International Conference on Particle Physics in memoriam Engin Arık and her Colleagues: Fatma Şenel Boydağ, İskender Hikmet, Mustafa Fidan, Berkol Doğan and Engin Abat was held at Doğuş University, İstanbul, Turkey on 20-25 June 2011. The conference was organized jointly by the Doğuş and Boğaziçi Universities, with support from CERN and the Turkish Academy of Sciences. This was the second International Conference on Particle Physics (ICPP) organized in memory of Engin Arık and her Colleagues who lost their lives in the tragic plane accident on November 30 2007, on their way to the workshop of the Turkish Accelerator Center (TAC) Project. The first of this conference series was held on 27-31 October 2008 at Boğaziçi University, İstanbul, Turkey. The conference is intended to be repeated every two years in Istanbul as a Conference Series under the name 'ICPP-Istanbul'. Professor Engin Arık had a pioneering role in experimental particle physics in Turkey, and was an inspiring teacher to many colleagues. She led the Turkish participation in experiments at CERN such as CHARMII, SMC, CHORUS, ATLAS and CAST. One of her latest involvements was in the national project to design the Turkish Accelerator Center with the collaboration of 10 Turkish universities including Doğuş and Boğaziçi. Our dear colleagues not only participated in the TAC project but also collaborated on the ATLAS (E Arık, E Abat and B Doğan) and CAST (E Arık, F Şenel Boydağ, İ Hikmet and B Doğan) experiments. We believe that the ICPP-Istanbul conference series has been, and will always be, a way to commemorate them in a most appropriate context. The topics covered in ICPP-Istanbul-II were 'LHC Physics and Tevatron Results', 'Neutrinos and Dark Matter', 'Particle Factories' and 'Accelerator Physics and Future TeV Scale Colliders'. The main emphasis was on the recent experimental results in high-energy physics with discussions on expectations from existing or future

  5. Buying green! A handbook on green energy procurement. 2nd edition

    NONE

    2011-11-10

    Over 2 trillion Euros is spent on public contracts on a yearly basis in the EU, translating to 19 percent of its GDP. ICLEI has been working with the European Commission to produce guidance on green public procurement (GPP) which will help public authorities to reduce their environmental impact, while complying with the procurement rules. The result is the new edition of the Buying Green! handbook. The handbook identifies strategies for GPP, and explains in detail how these can be implemented at each stage of the procurement process. It is intended for public sector procurers but is also a useful reference for policy makers and businesses who are either implementing their own green purchasing or responding to tenders. In addition to explaining how GPP can be implemented under the EU procurement rules, the handbook includes examples of green contracts from across the EU-27. The resource has been fully updated from the previous 2004 edition and includes expanded sections on life-cycle costing (LCC) and the construction, timber, electricity and food and drink sectors.

  6. Early prediction for necessity of 2nd I-131 ablation therapy with serum thyroglobulin levels in patients with differentiated thyroid cancer

    The aim of our study was to evaluate the predictive value of serum thyroglobulin levels, measured at preoperative status and just before 1st I-131 ablation therapy with high serum TSH, for necessity of 2nd I-131 ablation therapy in differentiated thyroid cancer patients. 111 patients with DTC who underwent total or near total thyroidectomy followed by immediate I-131 ablation therapy, were enrolled in this study. TSH, Tg and anti-Tg autoantibody were measured before thyroidectomy (TSHpreop, Tgpreop and Anti-Tgpreop) and just before 1st I-131 ablation therapy (TSHabl, Tgabl and Anti-Tgabl). All TSHabl levels were above 30mU/liter, ATg [(Tgpreop-Tgabl)X100/(Tgpreop)] was calculated. 29 patients(26.1%, 29/111) had to receive 2nd I-131 ablation therapy. Of 70 patients whose Tgabl were under 10 ng/ml, only 11 patients had received 2nd I-131 ablation therapy (15.7%). Patients with Tgabl greater than or equal to 10 ng/ml had received 2nd I-131 ablation therapy (18/41, 43.9%) than patients with lower Tgabl level. There was a disparity of necessity of 2nd I-131 ablation therapy between two groups(Tgabl <10 ng/ml and Tgabl =10 ng/ml, two by two /2 test p=0.0016). Of 41 patients with Tgabl greater than or equal to 10 ng/ml, 19 patients showed increased Tg levels (ATg<0). Patients with negative ATg and Tgabl greater than or equal to 10 ng/ml showed a strikingly high necessity of 2nd I-131 ablation therapy (11/19, 57.9%). There was also a significant disparity of necessity of 2nd I-131 ablation therapy between two groups(ATg<0 + Tgabl =10 ng/ml and the others, two by two /2 test, p=0.0012). These results suggest that high Tgabl level just before 1st I-131 ablation therapy can forecast the necessity of 2nd I-131 ablation therapy. Moreover, Difference of Tg level between preoperative status and just before 1st I-131 ablation therapy could also suggest necessity of 2nd I-131 ablation therapy at early period of DTC patients surveillance

  7. A summary of the 2nd workshop on Human Resources Development (HRD) in the nuclear field in Asia. FY2000

    NONE

    2001-06-01

    The Human Resources Development (HRD) Project was added in 1999 as a Cooperation Activity of 'the Forum for Nuclear Cooperation in Asia (FNCA)' which is organized by Nuclear Committee. The HRD Project supports to solidify the foundation of nuclear development utilization in Asia by promoting human resources development in Asian countries. The principal activity of the HRD Project is to hold the Workshop on Human Resources Development in the Nuclear Field in Asia once a year. The objective of the Workshop is to clarify problems and needs of the human resources development of each country and to support it mutually by exchanging information etc. The report consists of a summary of the 2nd Workshop on Human Resources Development in the Nuclear Field in Asia held on November 27 and 28, 2000 at Tokai Research Establishment of JAERI. (author)

  8. International collaborative study for establishment of the 2nd WHO International Standard for Haemophilus influenzae type b polysaccharide.

    Mawas, Fatme; Burkin, Karena; Dougall, Thomas; Saydam, Manolya; Rigsby, Peter; Bolgiano, Barbara

    2015-11-01

    In this report we present the results of a collaborative study for the preparation and calibration of a replacement International Standard (IS) for Haemophilus influenzae type b polysaccharide (polyribosyl ribitol phosphate; 5-d-ribitol-(1 → 1)-β-d-ribose-3-phosphate; PRP). Two candidate preparations were evaluated. Thirteen laboratories from 9 different countries participated in the collaborative study to assess the suitability and determine the PRP content of two candidate standards. On the basis of the results from this study, Candidate 2 (NIBSC code 12/306) has been established as the 2nd WHO IS for PRP by the Expert Committee of Biological Standards of the World Health Organisation with a content of 4.904 ± 0.185mg/ampoule, as determined by the ribose assays carried out by 11 of the participating laboratories. PMID:26298195

  9. A summary of the 2nd workshop on Human Resources Development (HRD) in the nuclear field in Asia. FY2000

    The Human Resources Development (HRD) Project was added in 1999 as a Cooperation Activity of 'the Forum for Nuclear Cooperation in Asia (FNCA)' which is organized by Nuclear Committee. The HRD Project supports to solidify the foundation of nuclear development utilization in Asia by promoting human resources development in Asian countries. The principal activity of the HRD Project is to hold the Workshop on Human Resources Development in the Nuclear Field in Asia once a year. The objective of the Workshop is to clarify problems and needs of the human resources development of each country and to support it mutually by exchanging information etc. The report consists of a summary of the 2nd Workshop on Human Resources Development in the Nuclear Field in Asia held on November 27 and 28, 2000 at Tokai Research Establishment of JAERI. (author)

  10. Results of the independent verification of radiological remedial action at 217 South 2nd East Street, Monticello, Utah (MS00097)

    In 1980 the site of a vanadium and uranium mill at Monticello, Utah, was accepted into the US Department of Energy's (DOE's) Surplus Facilities Management Program, with the objectives of restoring the government-owned mill site to safe levels of radioactivity, disposing of or containing the tailings in an environmentally safe manner, and performing remedial actions on off-site (vicinity) properties that had been contaminated by radioactive material resulting from mill operations. During 1985 and 1986, UNC Geotech, the remedial action contractor designated by DOE, performed remedial action on the vicinity property at 217 South 2nd East Street, Monticello, Utah. The Pollutant Assessments Group (PAG) of Oak Ridge National Laboratory was assigned the responsibility of verifying the data supporting the adequacy of remedial action and confirming the site's compliance with DOE guidelines. The PAG found that the site successfully meets the DOE remedial action objectives. Procedures used by PAG are described. 3 refs., 2 tabs

  11. Anatomy of a 2nd-order unconformity: stratigraphy and facies of the Bakken formation during basin realignment

    Skinner, Orion; Canter, Lyn; Sonnenfeld, Mark; Williams, Mark [Whiting Oil and Gas Corp., Denver, CO (United States)

    2011-07-01

    Because classic Laramide compressional structures are relatively rare, the Williston Basin is often considered as structurally simple, but because of the presence of numerous sub-basins, simplistic lithofacies generalization is impossible, and detailed facies mapping is necessary to unravel Middle Bakken paleogeography. The unconformity above the Devonian Three Forks is explained by the infilling and destruction of the Devonian Elk Point basin, prepares the Bakken system, and introduces a Mississippian Williston Basin with a very different configuration. Black shales are too often considered as deposits that can only be found in deep water, but to a very different conclusion must be drawn after a review of stratigraphic geometry and facies successions. The whole Bakken is a 2nd-order lowstand to transgressive systems tract lying below the basal Lodgepole, which represents an interval of maximal flooding. This lowstand to transgressive stratigraphic context explains why the sedimentary process and provenance shows high aerial variability.

  12. 2nd International Symposium "Atomic Cluster Collisions : Structure and Dynamics from the Nuclear to the Biological Scale"

    Solov'yov, Andrey; ISACC 2007; Latest advances in atomic cluster collisions

    2008-01-01

    This book presents a 'snapshot' of the most recent and significant advances in the field of cluster physics. It is a comprehensive review based on contributions by the participants of the 2nd International Symposium on Atomic Cluster Collisions (ISACC 2007) held in July 19-23, 2007 at GSI, Darmstadt, Germany. The purpose of the Symposium is to promote the growth and exchange of scientific information on the structure and properties of nuclear, atomic, molecular, biological and complex cluster systems studied by means of photonic, electronic, heavy particle and atomic collisions. Particular attention is devoted to dynamic phenomena, many-body effects taking place in cluster systems of a different nature - these include problems of fusion and fission, fragmentation, collective electron excitations, phase transitions, etc.Both the experimental and theoretical aspects of cluster physics, uniquely placed between nuclear physics on the one hand and atomic, molecular and solid state physics on the other, are discuss...

  13. Quality of care indicators in rectal cancer.

    Demetter, P; Ceelen, W; Danse, E; Haustermans, K; Jouret-Mourin, A; Kartheuser, A; Laurent, S; Mollet, G; Nagy, N; Scalliet, P; Van Cutsem, E; Van Den Eynde, M; Van de Stadt, J; Van Eycken, E; Van Laethem, J L; Vindevoghel, K; Penninckx, F

    2011-09-01

    Quality of health care is a hot topic, especially with regard to cancer. Although rectal cancer is, in many aspects, a model oncologic entity, there seem to be substantial differences in quality of care between countries, hospitals and physicians. PROCARE, a Belgian multidisciplinary national project to improve outcome in all patients with rectum cancer, identified a set of quality of care indicators covering all aspects of the management of rectal cancer. This set should permit national and international benchmarking, i.e. comparing results from individual hospitals or teams with national and international performances with feedback to participating teams. Such comparison could indicate whether further improvement is possible and/or warranted. PMID:22103052

  14. Transanal Evisceration Caused by Rectal Laceration

    Torres Sánchez, María Teresa; Richart Aznar, Jose Manuel; Martí Martínez, Eva María; Martínez-Abad, Manuel

    2014-01-01

    Transrectal evisceration caused by colorectal injury is an unusual entity. This pathology is more frequent in elderly patients and it is usually produced spontaneously. Rectal prolapse is the principal predisposing factor. An 81-year-old woman was taken to the hospital presenting exit of intestinal loops through the anus. After first reanimation measures, an urgent surgery was indicated. We observed the absence of almost every small intestine loop in the abdominal cavity; these had been moved to the pelvis. After doing the reduction, a 3 to 4 cm linear craniocaudal perforation in upper rectum was objectified, and Hartmann's procedure was performed. We investigated and knew that she frequently manipulate herself to extract her faeces. The fast preoperative management avoided a fatal conclusion or an extensive intestinal resection. Reasons that make us consider rectal self-injury as the etiologic factor are explained. PMID:24639971

  15. Evidence and research in rectal cancer

    The main evidences of epidemiology, diagnostic imaging, pathology, surgery, radiotherapy, chemotherapy and follow-up are reviewed to optimize the routine treatment of rectal cancer according to a multidisciplinary approach. This paper reports on the knowledge shared between different specialists involved in the design and management of the multidisciplinary ESTRO Teaching Course on Rectal Cancer. The scenario of ongoing research is also addressed. In this time of changing treatments, it clearly appears that a common standard for large heterogeneous patient groups have to be substituted by more individualised therapies based on clinical-pathological features and very soon on molecular and genetic markers. Only trained multidisciplinary teams can face this new challenge and tailor the treatments according to the best scientific evidence for each patient

  16. UFT (tegafur-uracil) in rectal cancer

    Casado, E; Pfeiffer, P; Feliu, J; González-Barón, M; Vestermark, L; Jensen, Helle Anita

    2008-01-01

    abstracts relating to clinical studies of UFT in the treatment of locally advanced rectal cancer (LARC). Pre- and postoperative studies carried out in patients with newly diagnosed or recurrent disease were included. RESULTS: The combination of UFT and radiotherapy was effective and well tolerated in the......BACKGROUND: Major achievements in the treatment of localised rectal cancer include the development of total mesorectal excision and the perioperative administration of radiotherapy in combination with continuous infusion (CI) 5-fluorouracil (5-FU). This multimodal approach has resulted in extended...... survival and lower local relapse rates, with the potential for sphincter-preserving procedures. However, CI 5-FU is inconvenient for patients and is costly. Oral fluoropyrimidines like UFT (tegafur-uracil) offer a number of advantages over 5-FU. METHODS: We undertook a review of published articles and...

  17. Management of radiation-induced rectal bleeding.

    Laterza, Liboria; Cecinato, Paolo; Guido, Alessandra; Mussetto, Alessandro; Fuccio, Lorenzo

    2013-11-01

    Pelvic radiation disease is one of the major complication after radiotherapy for pelvic cancers. The most commonly reported symptom is rectal bleeding which affects patients' quality of life. Therapeutic strategies for rectal bleeding are generally ignored and include medical, endoscopic, and hyperbaric oxygen treatments. Most cases of radiation-induced bleeding are mild and self-limiting, and treatment is normally not indicated. In cases of clinically significant bleeding (i.e. anaemia), medical therapies, including stool softeners, sucralfate enemas, and metronidazole, should be considered as first-line treatment options. In cases of failure, endoscopic therapy, mainly represented by argon plasma coagulation and hyperbaric oxygen treatments, are valid and complementary second-line treatment strategies. Although current treatment options are not always supported by high-quality studies, patients should be reassured that treatment options exist and success is achieved in most cases if the patient is referred to a dedicated centre. PMID:24101202

  18. Importance of surgical margins in rectal cancer.

    Mukkai Krishnamurty, Devi; Wise, Paul E

    2016-03-01

    Distal resection margin (DRM) and circumferential resection margin (CRM) are two important considerations in rectal cancer management. Although guidelines recommend a 2 cm DRM, studies have shown that a shorter DRM is adequate, especially in patients receiving neoadjuvant chemoradiation. Standardization of total mesorectal excision has greatly improved quality of CRM. Although more patients are undergoing sphincter-saving procedures, abdominoperineal resection is indicated for very distal tumors, and pelvic exenteration is often necessary for tumors involving pelvic organs. PMID:27094456

  19. MicroRNA in rectal cancer

    Azizian, Azadeh; Gruber, Jens; Ghadimi, B Michael; Gaedcke, Jochen

    2016-01-01

    In rectal cancer, one of the most common cancers worldwide, the proper staging of the disease determines the subsequent therapy. For those with locally advanced rectal cancer, a neoadjuvant chemoradiotherapy (CRT) is recommended before any surgery. However, response to CRT ranges from complete response (responders) to complete resistance (non-responders). To date we are not able to separate in advance the first group from the second, due to the absence of a valid biomarker. Therefore all patients receive the same therapy regardless of whether they reap benefits. On the other hand almost all patients receive a surgical resection after the CRT, although a watch-and-wait procedure or an endoscopic resection might be sufficient for those who responded well to the CRT. Being highly conserved regulators of gene expression, microRNAs (miRNAs) seem to be promising candidates for biomarkers. Many studies have been analyzing the miRNAs expressed in rectal cancer tissue to determine a specific miRNA profile for the ailment. Unfortunately, there is only a small overlap of identified miRNAs between different studies, posing the question as to whether different methods or differences in tissue storage may contribute to that fact or if the results simply are not reproducible, due to unknown factors with undetected influences on miRNA expression. Other studies sought to find miRNAs which correlate to clinical parameters (tumor grade, nodal stage, metastasis, survival) and therapy response. Although several miRNAs seem to have an impact on the response to CRT or might predict nodal stage, there is still only little overlap between different studies. We here aimed to summarize the current literature on rectal cancer and miRNA expression with respect to the different relevant clinical parameters. PMID:27190581

  20. Primary rectal melanoma - a case report

    Somak Das

    2015-01-01

    Full Text Available The most common site for malignant melanoma is skin, then eye and third is anorectal region. Primary anorectal malignant melanoma is still very uncommon. It is usually very aggressive and presents with altered bowel habit and rectal bleeding. Proctoscopy shows non-pigmented or lightly pigmented polypoid lesion. Histopathology is confirmatory. Early radical excision is mandatory. A 56 year-old female was presented with malignant melanoma of the lower third of rectum. We report this case for its rarity.

  1. Intraoperative radiotherapy in primary rectal cancer

    According to the results of several studies intraoperative radiotherapy seems to influence local control for primary rectal cancer in UICC-Stage II / III positively, though recommendations in therapy cannot be given as studies of high evidence level do not exist. As IORT is rarely available and makes patient recruitment difficult, prospective randomised trials have not been carried out yet. This emphasizes the importance of non-randomised trials for an evaluation of IORT. A comparison of 21 patients with locally advanced rectal cancer who had been treated with intraoperative radiation therapy and 21 similar cases without an application of IORT could not show any significant improvements in prognosis (recurrences, metastases and disease-specific survival). Nevertheless the employment of intraoperative radiation showed a trend in improvement of local control. This hast been shown by several other studies before. Thus the application of IORT in patients with locally advanced rectal cancer is considered a useful part in multimodal treatment and should further be evaluated in specialized centres. In case-control studies 1:1-matching leads to a good comparability of groups and renders conclusions of high internal validity possible. To gain a sufficient power, this type of trials should however primarily be carried out by centres with a high number of cases.

  2. Function-preserving surgery for rectal cancer

    When total mesorectal excision (TME) is accurately performed, dysfunction, theoretically, does not occur. However, there are differences among individuals in the running patterns and the volumes of nerve fibers, and if obesity or a narrow pelvis is present, nerve identification is difficult. Currently, the rate of urinary dysfunction after rectal surgery ranges from 33% to 70%. Many factors other than nerve preservation play a role in minor incontinence. Male sexual function shows impotence rates ranging from 20% to 46%, while 20%-60% of potent patients are unable to ejaculate. In women, information on sexual function is not easily obtained, and there are more unknown aspects than in men. As urinary, sexual, and defecation dysfunction due to adjuvant radiotherapy have been reported to occur at a high frequency, the creation of a protocol that enables analysis of long-term functional outcome will be essential for future clinical trials. In the treatment of rectal cancer, surgeon-related factors are extremely important, not only in achieving local control but also in preserving function. This article reviews findings from recent studies investigating urinary, sexual, and defecation dysfunction after rectal cancer surgery and discusses questions to be studied in the future. (author)

  3. Rectal Sedation with Thiopental in Children

    Objective: to determine the effectiveness of a rectal sedation protocol with sodium thiopental in children undergoing diagnostic imaging studies in a level-four-complexity health care facility. Materials and Methods: this case series observational study was developed between the months of January and March 2004 in the Fundacion clinica Valle del Lili. All pediatric patients between the ages of three months and eight years of age who underwent an imaging study were included. A dose of 25-40 mg/kg of sodium thiopental was administered rectally. Successful sedation was defined as one that allowed the successful completion of the study with the least number of motion artifacts. The features of the sedation and the adverse effects were evaluated. Results: the study population included 103 children with a median age of two years. The imaging studies were successfully concluded in 97% of the patients. The average total time until complete awakening was 2.9 hours. With respect to the interruption of sedation, we found statistically significant differences between the children who were kept awake the night before the procedure and those who were not. The most common adverse effect was diarrhea, which was recorded in 13 patients. Five of the patients required a supplemental dose of the sedative. There were two cases of increased salivation and one of vomiting, yet they resolved spontaneously. Conclusions: this rectal sodium thiopental protocol is a safe and effective procedure for the completion of diagnostic imaging studies in the pediatric population at our health care center.

  4. Value of protective stoma in rectal cancer surgery

    Fratrić Ivana; Radovanović Zoran; Radovanović Dragana; Vicko Ferenc; Petrović Tomislav; Nikin Zoran

    2016-01-01

    Introduction. Anastomotic leakage is the most serious surgical complication in rectal surgery. The aim of this study was to find out whether a protective stoma was capable of lowering the rate of clinical anastomotic leakage and to evaluate the rate of anastomotic leakages requiring re-surgery. Material and Methods. A retrospective study included a sample of 149 consecutive patients with rectal cancer who had undergone elective rectal resection with primary ...

  5. Rapid Dissemination of SIV Follows Multisite Entry after Rectal Inoculation

    Ribeiro dos Santos, Patricia; Rancez, Magali; Prétet, Jean-Luc; Michel-Salzat, Alice; Messent, Valérie; Bogdanova, Anna; Couëdel-Courteille, Anne; Souil, Evelyne; Cheynier, Rémi; Butor, Cécile

    2011-01-01

    Receptive ano-rectal intercourse is a major cause of HIV infection in men having sex with men and in heterosexuals. Current knowledge of the mechanisms of entry and dissemination during HIV rectal transmission is scarce and does not allow the development of preventive strategies. We investigated the early steps of rectal infection in rhesus macaques inoculated with the pathogenic isolate SIVmac251 and necropsied four hours to nine days later. All macaques were positive for SIV. Control macaqu...

  6. Preserving the superior rectal artery in laparoscopic [correction of laparoscopis] anterior resection for complete rectal prolapse.

    Ignjatovic, D; Bergamaschi, R

    2002-01-01

    Anterior resection for the treatment of full thickness rectal prolapse has been around for over four decades. 1 However, its use has been limited due to fear of anastomotic leakage and related morbidity. It has been shown that high anterior resection is preferable to its low counterpart as the latter increases complication rates. 2 Although sparing the inferior mesenteric artery in sigmoid resection for diverticular disease has been shown to decrease leak rates in a randomized setting, 3 vascular division is current practice. We shall challenged this current practice of dividing the mesorectum in anterior resection for complete rectal prolapse developing a technique that allows the preservation of the superior rectal artery. PMID:12587465

  7. Rectal Diclofenac Versus Rectal Paracetamol: Comparison of Antipyretic Effectiveness in Children

    Sharif, Mohammad Reza; Haji Rezaei, Mostafa; Aalinezhad, Marzieh; Sarami, Golbahareh; Rangraz, Masoud

    2016-01-01

    Background Fever is the most common complaint in pediatric medicine and its treatment is recommended in some situations. Paracetamol is the most common antipyretic drug, which has serious side effects such as toxicity along with its positive effects. Diclofenac is one of the strongest non-steroidal anti-inflammatory (NSAID) drugs, which has received little attention as an antipyretic drug. Objectives This study was designed to compare the antipyretic effectiveness of the rectal form of Paracetamol and Diclofenac. Patients and Methods This double-blind controlled clinical trial was conducted on 80 children aged six months to six years old. One group was treated with rectal Paracetamol suppositories at 15 mg/kg dose and the other group received Diclofenac at 1 mg/kg by rectal administration (n = 40). Rectal temperature was measured before and one hour after the intervention. Temperature changes in the two groups were compared. Results The average rectal temperature in the Paracetamol group was 39.6 ± 1.13°C, and 39.82 ± 1.07°C in the Diclofenac group (P = 0.37). The average rectal temperature, one hour after the intervention, in the Paracetamol and the Diclofenac group was 38.39 ± 0.89°C and 38.95 ± 1.09°C, respectively (P = 0.02). Average temperature changes were 0.65 ± 0.17°C in the Paracetamol group and 1.73 ± 0.69°C in the Diclofenac group (P < 0.001). Conclusions In the first one hour, Diclofenac suppository is able to control the fever more efficient than Paracetamol suppositories. PMID:26889398

  8. Low rectal cancer : aspects of surgical techniques and treatment results

    Anderin, Claes

    2012-01-01

    Rectal cancer is the 7th most common form of cancer in Sweden, both for men and women. About one third of all patients diagnosed with rectal cancer have a low tumour (i.e. 0-5 cm from the anal verge). Abdominoperineal excision (APE) is the most common surgical procedure in low rectal cancer, performed in approximately 80% of patients. While oncological outcomes in rectal cancer have improved in recent decades, the outcome after APE has remained poor and local recurrence rates have been report...

  9. Conservative treatment of premature rectal cancer

    Objectives: The largest radical resections in rectal cancer with significant morbidity and mortality (Urinary dysfunction, sexual dysfunction, permanent colostomy, etc.), on certain occasions and with high selectivity, they can be avoided with the implementation of local resections. Our intention is to assess the results of conservative treatment of rectal cancer early. Material and Methods: Between 01.01.89 and 31.12.09 14 consecutive patients were treated carriers rectal adenocarcinoma who had never received prior cancer treatment and a second simultaneous showed no neoplasia. The age of the patients presented a range between 44 and 72 years with a mean of 60.4 years; sex similarly partitioned and according to ECOG performance status was 0≤2. All patients were operated through a anal resection of which 4 were performed a submucosal tumor excision (T1) and 10 excision was entire rectal wall and tumor invaded the muscularis propria (T2). For this one type of surgery patients were selected the following criteria: tumor ≤6 cm. the anal verge, size ≤3 cm., GH I-II, vegetative, mobile, and T1-2, N0 by EER. After intervention, the pathological examination of the surgical specimen showed that 4 patients GH III, lymphovascular invasion and / or peri neural, or close surgical margins (+) (≤3 mm.) And T3, so underwent Miles operation (March 1 T1 and T2). Subsequently the rest of the patients (10) underwent concomitant radio chemotherapy. Radiation therapy was similar all using megavoltage photons (CO-60, 18mV) to the entire pelvic volume in a normofraccionamiento to complete 50.40 Gy (1.8 Gy / 28) using multiple fields (box technique). Chemotherapy was prepared 5FU + LV in the first patient (4), in following (4) was used 5FU continuous infusion (1st and 5th week) and the remaining (2) Capecitabine. Follow up was complete. Results: In our sample we extract local failure was 4 (29%), distant failure 3 (20%) and two local and distant failures (14%) so it follows that

  10. The stages of development a healthy way of life of senior pupils in native pedagogy (2nd part of XX century)

    Iermakova T.S.

    2010-01-01

    The stages of formation and development the problem of healthy way of life of senior pupils were defined in native pedagogy of 2nd part of XX century. The peculiarities of forming healthy way of life of senior pupils at every stage were analysed and disclosed. The contribution of native scientific and pedagogues of the 2nd part of XX century in solution of the problem of forming healthy way of life of senior pupils were determined. On the investigated stages were defined the imperfections tha...

  11. The Effects of Star Strategy of Computer-Assisted Mathematics Lessons on the Achievement and Problem Solving Skills in 2nd Grade Courses

    İPEK, Jale; Hatice Malaş

    2013-01-01

    The aim of research is to determine the effect of STAR strategy on 2nd grade students’ academic achievement and problem solving skills in the computer assisted mathematics instruction. 30 students who attend to 2nd grade course in a primary school in Aydın in 2010-2011 education year join the study group. The research has been taken place in 7 week. 3 types of tests have been used as means of data collecting tool, “Academic Achievement Test”, “Problem Solving Achievement Test” and “The Evalua...

  12. Clinical evaluation of the 2nd generation radio-receptor assay for anti-thyrotropin receptor antibodies (TRAb) in Graves' disease

    Full text: Detection of autoantibodies to the TSH receptor by radioreceptorial assays (RRA) is largely requested in clinical practice for the diagnosis of Graves' disease and its differentiation from diffuse thyroid autonomy. Additionally, TRAb measurement during antithyroid drug treatment can be useful to evaluate the risk of disease's relapse alter therapy discontinuation. Nevertheless, some patients affected by Graves' disease are TRAb negative when 1st generation assay is used. Recently a new RRA method for TRAb assay was developed by using human recombinant TSH-receptor and solid-phase technique. Aim of our work was the comparison between 1st and 2nd generation TRAb assays in Graves' disease patients and, particularly, the evaluation of 2nd generation test in a sub-group of patients affected by Graves' disease but with negative 1st generation TRAb assay. We evaluated the diagnostic performance of a newly developed 2nd generation TRAb assay (DYNOtest(r) TRAK human, BRAHMS Diagnostica GmbH, Germany) in 46 patients affected by Graves' disease with negative 1st generation TRAb assay (TRAK Assay(r), BRAHMS Diagnostica GmbH, Germany) . A control groups of 50 Graves' disease patients with positive 1st generation TRAb assay, 50 patients affected by Hashimoto's thyroiditis and 50 patients affected by nodular goiter were also examined. 41 out of 46 patients affected by Graves' disease with negative 1st generation TRAb assay showed a positive 2nd generation test. The overall sensitivity of the 2nd generation test was significantly improved respect the 1st generation assay in Graves' disease patients (χ2 = 22.5, p<0.0001). 1 and 3 out of 50 patients affected by Hashimoto's thyroiditis were positive by 1st and 2nd generation TRAB assay, respectively. All these patients showed primary hypothyroidism. No differences resulted in euthyroid Hashimoto's thyroiditis sub-group and in nodular goiter control group. The 2nd generation TRAB assay is clearly more sensitive than the 1

  13. MRI or CT for pretreatment staging and radiotherapy planning for radiochemotherapy in distal rectal cancer. Radiologists point

    Full text: Introduction: In the recent years, the therapeutic approach to rectal cancer changed dramatically. Implementation of a common mesorectal excision and preoperative radiotherapy has become a standard procedure. Noninvasive imaging methods have become basic and leading methods in the process of pre-therapy staging and rectal cancer radiotherapy planning. What you will learn : Following the recommendations of the 2013 ESGAR EURECCA 2012 we will present: a comparative data about the place and role of MRI and CT in the algorithm for low rectal carcinoma staging ; a standard MRI protocol for low rectum carcinoma staging as well as the questions concerning the image interpretation that the radiologist needs to answer. Discussion : Based on the European rules and consensus in the standard protocols implementation of in conducting MRI in rectal cancer, we have the opportunity for preoperative staging of the tumor and hence for proper treatment. The high spatial and tissue resolution of MRI allows carcinoma’s visualization at the depth infiltration of the wall of rectum, distance from mesorectal fascia, involvement of anorectal sphincter, pelvic floor and adjacent bodies, involvement of the venous plexus and the metastatic pararectal lymph nodes presence. Additional performed lung, abdomen and pelvis CT (MDCT) has limited chance for tumor staging, but it serves for distant metastases detection. Conclusion: MRI is the main method for T and N staging and re-staging of low carcinoma of the rectum. MDCT is used for determination of the N stages of the disease

  14. Quality of life after surgery for rectal cancer.

    Gavaruzzi, Teresa; Giandomenico, Francesca; Del Bianco, Paola; Lotto, Lorella; Perin, Alessandro; Pucciarelli, Salvatore

    2014-01-01

    Patients' health-related quality of life (HRQoL) is now considered a relevant clinical outcome. This study systematically reviewed articles published in the last 5 years, focusing on the impact of rectal cancer treatment on patients' HRQoL. Of the 477 articles retrieved, 56 met the inclusion criteria. The most frequently reported comparisons were between surgical procedures (21 articles), especially between sphincter-preserving and non-sphincter preserving surgery or between stoma and stoma-free patients (13 articles), and between multimodality therapies (11 articles). Additionally, twelve articles compared patients' and healthy controls' HRQoL as primary or secondary aim. The majority of the studies were observational (84 %), controlled (66 %), cross-sectional (54 %), prospective (100 %), with a sample of more than 100 patients (59 %), and with more than 60 % of patients treated with neoadjuvant therapy (50 %). The most frequently used instruments were the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30), its colorectal cancer specific module QLQ-CR38, and the Medical Outcomes Study Short-Form 36 items questionnaire. Findings from the included articles are summarised and commented, with a special focus on the comparison between surgical treatments, between irradiated and not-irradiated patients, and between patients and the general population. PMID:25103003

  15. Roles of doping ions in afterglow properties of blue CaAl2O4:Eu2+,Nd3+ phosphors

    Eu2+ doped and Nd3+ co-doped calcium aluminate (CaAl2O4:Eu2+,Nd3+) phosphor was prepared by a urea-nitrate solution combustion method at furnace temperatures as low as 500 °C. The produced CaAl2O4:Eu2+,Nd3+ powder was investigated in terms of phase composition, morphology and luminescence by X-Ray diffraction (XRD), Scanning Electron Microscope (SEM), Fourier Transform Infra Red spectroscopy (FTIR) and Photoluminescence (PL) techniques respectively. XRD analysis depicts a dominant monoclinic phase that indicates no change in the crystalline structure of the phosphor with varying concentration of Eu2+ and Nd3+. SEM results show agglomerates with non-uniform shapes and sizes with a number of irregular network structures having lots of voids and pores. The Energy Dispersive X-ray Spectroscopy (EDS) and (FTIR) spectra confirm the expected chemical components of the phosphor. PL measurements indicated one broadband excitation spectra from 200 to 300 nm centered around 240 nm corresponding to the crystal field splitting of the Eu2+ d-orbital and an emission spectrum in the blue region with a maximum on 440 nm. This is a strong indication that there was dominantly one luminescence center, Eu2+ which represents emission from transitions between the 4f7 ground state and the 4f6–5d1 excited state configuration. High concentrations of Eu2+ and Nd3+ generally reduce both intensity and lifetime of the phosphor powders. The optimized content of Eu2+ is 1 mol% and for Nd3+ is 1 mol% for the obtained phosphors with excellent optical properties. The phosphor also emits visible light at around 587 and 616 nm. Such emissions can be ascribed to the 5D0–7F1 and 5D0–7F2 intrinsic transition of Eu3+ respectively. The decay characteristics exhibit a significant rise in initial intensity with increasing Eu2+ doping concentration while the decay time increased with Nd3+ co-doping. The observed afterglow can be ascribed to the generation of suitable traps due to the presence of the Nd

  16. Is rectal MRI beneficial for determining the location of rectal cancer with respect to the peritoneal reflection?

    An objective method for determining the location of the cancer with respect to peritoneal reflection would be helpful to decide the treatment modality for rectal cancer. This study was designed to evaluate the accuracy and usefulness of rectal MRI to determine spatial relations between the peritoneal reflection and rectal cancer and to compare these with operative findings. Patients that underwent a rectal cancer operation after a rectal MRI check between November 2008 and June 2010 were considered for the study. The patients that received preoperative concurrent chemoradiation or trans-anal local excision were excluded. Fifty-four patients constituted the study cohort. By comparing surgical and radiologic findings, the accuracy for predicting tumour location in relation to the peritoneal reflection by rectal MRI in all patients was 90.7%. In terms of tumour location in relation to peritoneal reflection, the accuracy of rectal MRI was 93.5% in patients with a tumour located above the peritoneal reflection, 90.0% in patients with a tumour located on the peritoneal reflection, and 84.6% in patients with a tumour located below the peritoneal reflection (p=0.061). When the cohort was subdivided by gender, body mass index (BMI), operative findings, or tumour size, no significant difference was observed among subgroups. Rectal MRI could be a useful tool for evaluating the relation between rectal cancer and peritoneal reflection especially when tumour size is less than 8cm. Rectal MRI can provide information regarding the location of rectal cancer in relation to the peritoneal reflection for treatment planning purposes

  17. The 2008—2013 crisis as metastasis : a preview of the 2nd edition of The cancer stage of capitalism by Pluto Press

    John McMurtry

    2013-01-01

    By means of selection of relevant excerpts, a preview is offered hereby of the 2nd edition of John McMurtry's prophetic 1999 book "The Cancer Stage of Capitalism", published by Pluto Press, and entitled "The Cancer Stage of Capitalism and Its Cure"

  18. The 2008—2013 Crisis as Metastasis. A Preview of the 2nd edition of The Cancer Stage of Capitalism by Pluto Press

    John McMurtry

    2013-03-01

    Full Text Available By means of selection of relevant excerpts, a preview is offered hereby of the 2nd edition of John McMurtry's prophetic 1999 book "The Cancer Stage of Capitalism", published by Pluto Press, and entitled "The Cancer Stage of Capitalism and Its Cure"

  19. Design of control system for the 2nd and 3rd charge exchange system in J-PARC 3GeV RCS

    J-PARC 3GeV Synchrotron Accelerator is using method of charge exchange injection using three carbon foils. In order to achieve this injection, three charge exchange devices installed in this facility. These devices are controlled by one control system. The 2nd and 3rd charge exchange devices are upgrading to increase maintainability and exhaust ability of the vacuum unit, and the control system has reconsidered. Basic policy of redesigning the control system is separated from centralized control system of the three devices, and we reconstruct the control system that independent from the centralized control system. On this condition, we are upgrading of the 2nd and 3rd charge exchange device. It is necessary to redesign the interlock unit about safety, because of being stand-alone control. Now, the error signal of the charge exchange unit consolidates the error signal of three devices, and it operates the Machine Protection System (MPS). Therefore, we needed long time to search occasion why the error happened. However, the MPS will be operated by the error signal on each unit, we hope it makes a difference to search occasion easily. The 2nd and 3rd charge exchange units adopt a simple control system using Yokogawa electric PLC FA-M3. We are designing of the control system with safety that fuses the drive unit and the vacuum unit. This report is about design of the 2nd and 3rd charge exchange unit control system that reconstructed the hardware of their unit. (author)

  20. Cogeneration and production of 2nd generation bio fuels using biomass gasification; Cogeneracion y produccion de biocombustibles de 2 generacion mediante gasificacion de biomasa

    Uruena Leal, A.; Diez Rodriguez, D.; Antolin Giraldo, G.

    2011-07-01

    Thermochemical decomposition process of gasification, in which a carbonaceous fuel, under certain conditions of temperature and oxygen deficiency, results in a series of reactions that will produce a series of gaseous products is now widely used for high performance energetic and versatility of these gaseous products for energy and 2nd generation bio fuels and reduce the emission of greenhouse gases. (Author)

  1. Dielectric properties of [Ca1-x(Li1/2Nd1/2)x]1-yZnyTiO3 ceramics at microwave frequencies

    Dielectric properties of Ca1-x(Li1/2Nd1/2)xTiO3 (0.0≤x≤0.6, CLNT) and [Ca0.6(Li1/2Nd1/2)0.4]1-yZnyTiO3 (0.5≤y≤1.0, CLNZT) ceramics were investigated at 4-10 GHz. For the CLNT system, a single perovskite phase was detected in the entire composition range. The dielectric constants (K), and the temperature coefficients of the resonant frequency (TCF) were dependent on the B-site bond valence. Qf value decreases with the increase in (Li1/2Nd1/2)TiO3 content (x) due to a decrease in grain size. For the CLNZT system, Qf value and TCF were improved with Zn content (y) due to the formation of Zn2TiO4. Typically, K of 47, Qf of 13000 GHz, TCF of 14 ppm per deg. C were obtained for [Ca0.6(Li1/2Nd1/2)0.4]0.4Zn0.6TiO3 sintered at 1150 deg. C for 4 h

  2. Growth, structure, and optical properties of a self-activated crystal: Na2Nd2O(BO3)2

    Shan, Faxian; Zhang, Guochun; Yao, Jiyong; Xu, Tianxiang; Zhang, Xinyuan; Fu, Ying; Wu, Yicheng

    2015-08-01

    A self-activated crystal Na2Nd2O(BO3)2 has been grown from the Na2O-Nd2O3-B2O3-NaF system. Its structure was determined by single crystal X-ray diffraction, and verified by infrared spectrum and inductively coupled plasma optical emission spectrometry. Na2Nd2O(BO3)2 crystallizes in the monoclinic crystal system, space group P21/c with unit-cell parameters a = 10.804 Å, b = 6.421 Å, c = 10.450 Å, β = 117.95°, Z = 4, and V = 640.4 Å3. Its absorption and emission spectra were measured at room temperature. Based on the absorption spectrum, the spontaneous transition probabilities, fluorescence branch ratio, and the radiation lifetime of 4F3/2 state were calculated. The emission properties under the 355 nm excitation were also evaluated. The electronic structure of Na2Nd2O(BO3)2 was calculated by the first-principles method. The obtained results show that Na2Nd2O(BO3)2 may be a promising microchip laser material.

  3. White paper on perspectives of biofuels in Denmark - with focus on 2nd generation bioethanol; Hvidbog om perspektiver for biobraendstoffer i Danmark - med fokus paa 2. generations bioethanol

    Larsen, Gy.; Foghmar, J.

    2009-11-15

    The white paper presents the perspectives - both options and barriers - for a Danish focus on production and use of biomass, including sustainable 2nd generation bioethanol, for transport. The white paper presents the current knowledge of biofuels and bioethanol and recommendations for a Danish strategy. (ln)

  4. Short rare hTERT-VNTR2-2nd alleles are associated with prostate cancer susceptibility and influence gene expression

    The hTERT (human telomerase reverse transcriptase) gene contains five variable number tandem repeats (VNTR) and previous studies have described polymorphisms for hTERT-VNTR2-2nd. We investigated how allelic variation in hTERT-VNTR2-2nd may affect susceptibility to prostate cancer. A case-control study was performed using DNA from 421 cancer-free male controls and 329 patients with prostate cancer. In addition, to determine whether the VNTR polymorphisms have a functional consequence, we examined the transcriptional levels of a reporter gene linked to these VNTRs and driven by the hTERT promoter in cell lines. Three new rare alleles were detected from this study, two of which were identified only in cancer subjects. A statistically significant association between rare hTERT-VNTR2-2nd alleles and risk of prostate cancer was observed [OR, 5.17; 95% confidence interval (CI), 1.09-24.43; P = 0.021]. Furthermore, the results indicated that these VNTRs inserted in the enhancer region could influence the expression of hTERT in prostate cancer cell lines. This is the first study to report that rare hTERT VNTRs are associated with prostate cancer predisposition and that the VNTRs can induce enhanced levels of hTERT promoter activity in prostate cancer cell lines. Thus, the hTERT-VNTR2-2nd locus may function as a modifier of prostate cancer risk by affecting gene expression

  5. Laparoscopic versus open surgery for rectal cancer (COLOR II)

    van der Pas, Martijn Hgm; Haglind, Eva; Cuesta, Miguel A;

    2013-01-01

    Laparoscopic surgery as an alternative to open surgery in patients with rectal cancer has not yet been shown to be oncologically safe. The aim in the COlorectal cancer Laparoscopic or Open Resection (COLOR II) trial was to compare laparoscopic and open surgery in patients with rectal cancer....

  6. Single-port laparoscopic rectal surgery - a systematic review

    Lolle, Ida; Rosenstock, Steffen; Bulut, Orhan

    2014-01-01

    INTRODUCTION: Single-port laparoscopic surgery (SPLS) for colonic disease has been widely described, whereas data for SPLS rectal resection are sparse. This review aimed to evaluate the feasibility, safety and complication profile of SPLS for rectal diseases. METHODS: A systematic literature search...

  7. VMAT planning study in rectal cancer patients

    To compare the dosimetric differences among fixed field intensity-modulated radiation therapy (IMRT), single-arc volumetric-modulated arc therapy (SA-VMAT) and double-arc volumetric-modulated arc therapy (DA-VMAT) plans in rectal cancer. Fifteen patients with rectal cancer previously treated with IMRT in our institution were selected for this study. For each patient, three plans were generated with the planning CT scan: one using a fixed beam IMRT, and two plans using the VMAT technique: SA-VMAT and DA-VMAT. Dose prescription to the PTV was 50 Gy in 2 Gy per fraction. Dose volume histograms (DVH) for the target volume and the organs at risk (small bowel, bladder, femoral heads and healthy tissue) were compared for these different techniques. Monitor units (MU) and delivery treatment time were also reported. DA-VMAT achieved the highest minimum planning target volume (PTV) dose and the lowest maximal dose, resulting in the most homogeneous PTV dose distribution. DA-VMAT also yielded the best CI, although the difference was not statistically significant. Between SA-VMAT and IMRT, the target dose coverage was largely comparable; however, SA-VMAT was able to achieve a better V95 and V107. VMAT showed to be inferior to IMRT in terms of organ at risk sparing, especially for the small bowel. Compared with IMRT, DA-VMAT increased the V15 of small bowel nearly 55 cc. The MU and treatment delivery time were significantly reduced by the use of VMAT techniques. VMAT is a new radiation technique that combines the ability to achieve highly conformal dose distributions with highly efficient treatment delivery. Considering the inferior role of normal tissue sparing, especially for small bowel, VMAT need further investigation in rectal cancer treatment

  8. Rectal Plasmocytoma: cases report and literature revision

    Plasma cell neoplasia occur in the malignant transformation of the early cell β precursors and plasma cells may group together in isolation in bones and other soft tissues without systemic manifestations; they are called plasmocytomas. Plasmocytomas outside the marrow are a rare presentation of plasma cell neoplasia. Only l % of these tumors present outside the bone marrow, two cases of rectal plasmocytoma are discussed, one of which was treated by pelvic radiotherapy and the other with surgical resection; at the time or this publication, neither shows any evidence of systemic disease

  9. Predictors for Rectal and Intestinal Acute Toxicities During Prostate Cancer High-Dose 3D-CRT: Results of a Prospective Multicenter Study

    Purpose: To find predictors for rectal and intestinal acute toxicity in patients with prostate cancer treated with ≥70 Gy conformal radiotherapy. Methods and Materials: Between July 2002 and March 2004, 1,132 patients were entered into a cooperative study (AIROPROS01-02). Toxicity was scored using the Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer scale and by considering the changes (before and after treatment) of the scores of a self-administered questionnaire on rectal/intestinal toxicity. The correlation with a number of parameters was assessed by univariate and multivariate analyses. Concerning the questionnaire, only moderate/severe complications were considered. Results: Of 1,132 patients, 1,123 were evaluable. Of these patients, 375, 265, and 28 had Grade 1, 2, and 3 Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer toxicity, respectively. The mean rectal dose was the most predictive parameter (p = 0.0004; odds ratio, 1.035) for Grade 2 or worse toxicity, and the use of anticoagulants/antiaggregants (p 0.02; odds ratio, 0.63) and hormonal therapy (p = 0.04, odds ratio, 0.65) were protective. The questionnaire-based scoring revealed that a greater mean rectal dose was associated with a greater risk of bleeding; larger irradiated volumes were associated with frequency, tenesmus, incontinence, and bleeding; hormonal therapy was protective against frequency and tenesmus; hemorrhoids were associated with a greater risk of tenesmus and bleeding; and diabetes associated highly with diarrhea. Conclusion: The mean rectal dose correlated with acute rectal/intestinal toxicity in three-dimensional conformal radiotherapy for prostate cancer, and hormonal therapy and the use of anticoagulants/antiaggregants were protective. According to the moderate/severe injury scores on the self-assessed questionnaire, several clinical and dose-volume parameters were independently predictive for

  10. High resolution MRI via endorectal coil. Results in rectal tumors

    10 volunteers and in 31 patients with suspected rectal tumors were examined. In 17 patients (n=17) with rectal carcinoma, of which 15 subsequently underwent radical surgery, the preoperatively obtained tumor stage was compared with histology. In 12 patients (n=12) with rectal adenoma (severe and medium graded epithelial dysplasias according to the WHO) who underwent endoscopy the results of the endorectal surface coil examination were compared with endoscopy and histology. In 4 patients (n=4) with large rectal adenomas the surface coil was used before and as follow-up after endoscopic electro laser resection and the absence of adenoma after therapy also in the deeper layers of the rectal wall could be confirmed. Visualization of anatomical structures of rectum and adjacent structures is improved by the use of the endorectal surface coil. The diagnosis of carcinoma and adenoma of the rectum and the documentation of the exact extension can be reached with high accuracy (85%). (orig./MG)

  11. Anatomo surgical study on radical mesorectum excision in rectal cancer.

    Alejandro A. Gorodner

    2010-11-01

    Full Text Available Knowledge of surgical anatomy of the mesorectum is essential for cancer surgery in rectal cancer. Radical mesorectal excision allows an appropriate surgery, preserving the pelvic nerves of the autonomic system, preventing postsurgical morbidity. The aim of this paper is to describe the anatomy of the mesorectum as a cornerstone to achieve a careful and detailed technique on rectal cancer surgery. 10 (ten adult formalized cadavers were dissected (nine male and one female specimen. Anatomical elements, both nervous and vascular were explored, in order to recognize those elements that should be preserved in rectal cancer surgery with radical mesorectal excision. The dissection of corpses may be an experimental model to test this type of cancer surgery. Samples were photographed and compared with those made in vivo. Rectal resection with its corresponding mesorectum, accordingly to the location of the tumor improves survival of patients with rectal cancer. Knowledge of the anatomy of the pelvic neurovascular elements significantly reduces postsurgical morbidity.

  12. Evolution of Corruption in Sub-Saharan Africa - from Nkruma To Mutharika The 2nd: Case Study Of South Africa

    Mavhungu Abel Mafukata

    2015-03-01

    Full Text Available Since Sub-Saharan Africa's first independence in Ghana, the region has experienced massive and costly political and bureaucratic corruption within public service and administration. The causes of the corruption, its nature and form are wide and intertwined. In Sub-Saharan Africa, efforts to curb corruption have failed to discard it. The paper focused on the period from Nkruma in Ghana to Mutharika the 2nd in Malawi. This paper reviewed existing literature on political and bureaucratic corruption in Sub-Saharan Africa while on the other hand the paper employed key informant interviews to gather the required data to investigate, analyse and profile the genesis and evolution of corruption in Sub-Saharan Africa. The key informant interviews were employed to solicit public views and opinion from nineteen key informant participants (n=19 selected from 11 countries in Sub-Saharan Africa. The paper found that corruption is legendary; has entrenched itself to becoming some sort of culture in the region, and has become the most difficult socio-economic challenge to resolve in the region despite the various anti-corruption efforts employed by stakeholders to curb it. It emerged through the study that law-enforcement efforts against corruption need some reinforcement in order to be effective and eficient in uprooting corruption in the region. If Sub-Saharan Africa fails to address its corruption challenge, its development prospects would seriously curtailed.

  13. Near infrared emission and energy transfer in Eu2+ - Nd3+ co-doped Ca2BO3Cl

    Talewar, R. A.; Joshi, C. P.; Moharil, S. V.

    2016-05-01

    Novel near infrared (NIR) emitting phosphor, Ca2BO3Cl:Eu2+, Nd3+ was synthesized by conventional solid-state reaction and characterized with X-ray diffraction, photoluminescence emission, photoluminescence excitation spectra and fluorescence decay measurements. When excited with 400 nm, the phosphor gives broadband emission at 560 nm, which corresponds to the allowed 5d → 4f transition of Eu2+ and an intense NIR emissions in the range 800-1400 nm, which are assigned to the characteristic 4I9/2,11/2,13/2 transitions of Nd3+ ions. The dependence of visible and NIR emissions, decay lifetime and the energy transfer efficiency (ηETE) were investigated in detail. The luminescence spectra, both in visible (VIS) and NIR regions, and decay lifetime curves of Eu2+ have been measured to prove energy transfer (ET) from Eu2+ to Nd3+. These results demonstrate the possibility for enhancing the photovoltaic conversion efficiency of silicon solar cell by modifying the absorption and utilizing the UV to blue part of the solar spectrum where the efficiency of c-Silicon solar cell is low.

  14. Inelastic neutron scattering studies on the 3d-4f heterometallic single-molecule magnet Mn2Nd2

    The discovery of slow relaxation and quantum tunneling of the magnetization in Mn12ac more than 15 years ago has inspired both physicists and chemists alike. This class of molecules, now called single-molecule magnets (SMMs), has very recently been expanded to heterometallic clusters incorporating transition metal and rare earth ions. The 4f ions were chosen because of their large angular momentum and magnetic anisotropy. Inelastic neutron scattering experiments were performed on the time-of-flight disk-chopper spectrometer IN5 at ILL on the SMM Mn2Nd2. A magnetic model was developed which perfectly describes all data, including the magnetic data. It was found that neither the large anisotropy nor the large angular momentum of the NdIII ions is the main reason for the SMM behavior in this molecule. Our analysis of the data indicates that it is the weak coupling of the NdIII ions to the MnIII ions, usually considered as a drawback of rare earth ions, which enhances the relaxation time and therefore leads to SMM behavior.

  15. Rectal dexmedetomidine in rats: evaluation of sedative and mucosal effects

    Volkan Hanci

    2015-02-01

    Full Text Available BACKGROUND AND OBJECTIVES: In this study, we investigated the anesthetic and mucosal effects of the rectal application of dexmedetomidine to rats. METHODS: Male Wistar albino rats weighing 250-300 g were divided into four groups: Group S (n = 8 was a sham group that served as a baseline for the normal basal values; Group C (n = 8 consisted of rats that received the rectal application of saline alone; Group IPDex (n = 8 included rats that received the intraperitoneal application of dexmedetomidine (100 µg kg-1; and Group RecDex (n = 8 included rats that received the rectal application of dexmedetomidine (100 µg kg-1. For the rectal drug administration, we used 22 G intravenous cannulas with the stylets removed. We administered the drugs by advancing the cannula 1 cm into the rectum, and the rectal administration volume was 1 mL for all the rats. The latency and anesthesia time (min were measured. Two hours after rectal administration, 75 mg kg-1 ketamine was administered for intraperitoneal anesthesia in all the groups, followed by the removal of the rats' rectums to a distal distance of 3 cm via an abdominoperineal surgical procedure. We histopathologically examined and scored the rectums. RESULTS: Anesthesia was achieved in all the rats in the Group RecDex following the administration of dexmedetomidine. The onset of anesthesia in the Group RecDex was significantly later and of a shorter duration than in the Group IPDEx (p < 0.05. In the Group RecDex, the administration of dexmedetomidine induced mild-moderate losses of mucosal architecture in the colon and rectum, 2 h after rectal inoculation. CONCLUSION: Although 100 µg kg-1 dexmedetomidine administered rectally to rats achieved a significantly longer duration of anesthesia compared with the rectal administration of saline, our histopathological evaluations showed that the rectal administration of 100 µg kg-1 dexmedetomidine led to mild-moderate damage to the mucosal structure of the

  16. 2nd ISAAC Congress

    Gilbert, Robert; Kajiwara, Joji

    2000-01-01

    This book is the Proceedings of the Second ISAAC Congress. ISAAC is the acronym of the International Society for Analysis, its Applications and Computation. The president of ISAAC is Professor Robert P. Gilbert, the second named editor of this book, e-mail: gilbert@math.udel.edu. The Congress is world-wide valued so highly that an application for a grant has been selected and this project has been executed with Grant No. 11-56 from *the Commemorative Association for the Japan World Exposition (1970). The finance of the publication of this book is exclusively the said Grant No. 11-56 from *. Thus, a pair of each one copy of two volumes of this book will be sent to all contributors, who registered at the Second ISAAC Congress in Fukuoka, free of charge by the Kluwer Academic Publishers. Analysis is understood here in the broad sense of the word, includ­ ing differential equations, integral equations, functional analysis, and function theory. It is the purpose of ISAAC to promote analysis, its applications, and...

  17. 2nd Abel Symposium

    Nunno, Giulia; Lindstrøm, Tom; Øksendal, Bernt; Zhang, Tusheng

    2007-01-01

    Kiyosi Ito, the founder of stochastic calculus, is one of the few central figures of the twentieth century mathematics who reshaped the mathematical world. Today stochastic calculus is a central research field with applications in several other mathematical disciplines, for example physics, engineering, biology, economics and finance. The Abel Symposium 2005 was organized as a tribute to the work of Kiyosi Ito on the occasion of his 90th birthday. Distinguished researchers from all over the world were invited to present the newest developments within the exciting and fast growing field of stochastic analysis. The present volume combines both papers from the invited speakers and contributions by the presenting lecturers. A special feature is the Memoirs that Kiyoshi Ito wrote for this occasion. These are valuable pages for both young and established researchers in the field.

  18. 2nd SUMO Conference

    Weber, Melanie

    2015-01-01

    This contributed volume contains the conference proceedings of the Simulation of Urban Mobility (SUMO) conference 2014, Berlin. The included research papers cover a wide range of topics in traffic planning and simulation, including open data, vehicular communication, e-mobility, urban mobility, multimodal traffic as well as usage approaches. The target audience primarily comprises researchers and experts in the field, but the book may also be beneficial for graduate students.  

  19. 2nd INTERA Conference

    2014-01-01

    This book presents the latest scientific research related to the field of Robotics. It involves different topics such as biomedicine, energy efficiency and home automation and robotics.  The book is written by technical experts and researchers from academia and industry working on robotics applications.The book could be used as supplementary material for courses related to Robotics and Domotics.

  20. 2nd Bozeman Conference

    Lund, John

    1991-01-01

    This volume contains a collection of papers delivered by the partici­ pants at the second Conference on Computation and Control held at Mon­ tana State University in Bozeman, Montana from August 1-7, 1990. The conference, as well as this proceedings, attests to the vitality and cohesion between the control theorist and the numerical analyst that was adver­ tised by the first Conference on Computation and Control in 1988. The proceedings of that initial conference was published by Birkhiiuser Boston as the first volume of this same series entitled Computation and Control, Proceedings of the Bozeman Conference, Bozeman, Montana, 1988. Control theory and numerical analysis are both, by their very nature, interdisciplinary subjects as evidenced by their interaction with other fields of mathematics and engineering. While it is clear that new control or es­ timation algorithms and new feedback design methodologies will need to be implemented computationally, it is likewise clear that new problems in computation...

  1. European communion

    Manners, Ian James

    2013-01-01

    relations (or not), and the consequences of these beliefs for European political projects, processes and products. By exploring European communion through an engagement with contemporary political theory, using very brief illustrations from the Treaty of Lisbon, the article also suggests that European...

  2. European elections

    In the framework of the european elections of june 2004, the author takes stock on the main european institutions and their functions. Since many years the European Union promotes the development of the renewable energies and the energy efficiency. This promotion is based on directives and support programs. Meanwhile the France delays the transposition of these directives. (A.L.B.)

  3. A comparison of aerosol chemical and optical properties from the 1st and 2nd Aerosol Characterization Experiments

    P. K. Quinn; T. S. Bates; Coffman, D. J.; Miller, T L; J. E. Johnson; D. S. Covert; Putaud, J.-P.; Neusüß, C.; Novakov, T.

    2011-01-01

    Shipboard measurements of aerosol chemical composition and optical properties were made during both ACE-1 and ACE-2. ACE-1 focused on remote marine aerosol minimally perturbed by continental sources. ACE-2 studied the outflow of European aerosol into the NE Atlantic atmosphere. A variety of air masses were sampled during ACE-2 including Atlantic, polar, Iberian Peninsula, Mediterranean, and Western European. Reported here are mass size distributions of non-sea salt (nss) sulfate, sea salt, an...

  4. Conservative management of anal and rectal cancer

    The role of irradiation in the management of anal and rectal cancer has changed during the past ten years. In small epidermoid carcinomas of the anal canal (T1 T2) irradiation is in most departments considered the primary treatment, giving a 5-year survival rate of between 60 and 80% with good sphincter preservation. Even in larger tumors, irradiation can still offer some chance of cure without colostomy. Surgery remains the basic treatment of rectal cancer but irradiation is used in association with surgery in many cases. Radiotherapy is of value in the conservative management of cancer of the rectum in three situations: In small polypoid cancers contact X-ray therapy can give local control in about 90%. In cancers of the middle rectum, preoperative external irradiation may increase the chances of restorative surgery and reduce the risk of local relapse. In inoperable patients, external radiotherapy and/or intracavitary irradiation may cure some patients with infiltrating tumors (T2 T3) without colostomy. (orig.)

  5. Patient-reported genitourinary dysfunction after laparoscopic and open rectal cancer surgery in a randomized trial (COLOR II)

    Andersson, J; Abis, G; Gellerstedt, M; Angenete, E; Angerås, U; Cuesta, M A; Jess, P; Rosenberg, J; Bonjer, H J; Haglind, E

    2014-01-01

    BACKGROUND: This article reports on patient-reported sexual dysfunction and micturition symptoms following a randomized trial of laparoscopic and open surgery for rectal cancer. METHODS: Patients in the COLOR II randomized trial, comparing laparoscopic and open surgery for rectal cancer, completed...... the European Organization for Research and Treatment of Cancer (EORTC) QLQ-CR38 questionnaire before surgery, and after 4 weeks, 6, 12 and 24 months. Adjusted mean differences on a 100-point scale were calculated using changes from baseline value at the various time points in the domains of sexual...... functioning, sexual enjoyment, male and female sexual problems, and micturition symptoms. RESULTS: Of 617 randomized patients, 385 completed this phase of the trial. Their mean age was 67·1 years. Surgery caused an anticipated reduction in genitourinary function after 4 weeks, with no significant differences...

  6. Weight change later in life and colon and rectal cancer risk in participants in the EPIC-PANACEA study

    Steins Bisschop, Charlotte N; van Gils, Carla H; Emaus, Marleen J;

    2014-01-01

    BACKGROUND: A moderate association exists between body mass index (BMI) and colorectal cancer. Less is known about the effect of weight change. OBJECTIVE: We investigated the relation between BMI and weight change and subsequent colon and rectal cancer risk. DESIGN: This was studied among 328...... used to study the association. RESULTS: A total of 1261 incident colon cancer and 747 rectal cancer cases were identified. BMI at recruitment was statistically significantly associated with colon cancer risk in men (HR: 1.04; 95% CI: 1.02, 1.07). Moderate weight gain (quintile 4) in men increased risk......,781 participants in the prospective European Prospective Investigation into Cancer-Physical Activity, Nutrition, Alcohol, Cessation of Smoking, Eating study (mean age: 50 y). Body weight was assessed at recruitment and on average 5 y later. Self-reported weight change (kg/y) was categorized in sex...

  7. Basic Space Science; United Nations/European Space Agency Workshops for Developing Countries, 2nd, Bogota, Colombia, November 9-13, 1992

    Haubold, Hans J. (Editor); Torres, Sergio (Editor)

    1994-01-01

    The conference primarily covered astrophysical and astronomical topics on stellar and solar modeling and processes, high magnetic field influence on stellar spectra, cosmological topics utilizing Cosmic Background Explorer (COBE) data and radioastronomic mapping as well as cosmic gravitational instability calculations, astrometry of open clusters amd solar gravitational focusing, extremely energetic gamma rays, interacting binaries, and balloon-borne instrumentation. Other papers proposed an active Search for Extraterrestrial Intelligence (SETI) communication scheme to neighboring solar-like systems and more direct involvement of and with the public in astronomy and space exploration projects.

  8. The solitary rectal ulcer syndrome: diagnosis with defecography.

    Goei, R; Baeten, C; Janevski, B; van Engelshoven, J

    1987-11-01

    The solitary rectal ulcer syndrome is an uncommon entity consisting of a rectal abnormality caused by straining during defecation and characterized by specific histologic changes. Endoscopy may show single or multiple ulcers or a preulcerative phase consisting of mucosal thickening. Findings on barium enema may be normal or nonspecific, consisting of a thickened valve of Houston, nodularity, and rectal stricture. Pathologic changes consist of replacement of the lamina propria by fibroblasts and smooth muscle fibers with marked hypertrophy of the muscularis mucosae. In five patients with histologically proved solitary rectal ulcer syndrome, defecography was performed to evaluate the accompanying defecation disorder. Two patients showed the spastic pelvic floor syndrome, characterized by failure of relaxation of the pelvic floor musculature during straining. In the remaining three, defecography showed an infolding of the rectal wall toward the rectal lumen increasing gradually to form an intussusception. The results indicate that defecography is useful to show the underlying disorder of defecation in the solitary rectal ulcer syndrome. PMID:3499797

  9. Bupivacaine administered intrathecally versus rectally in the management of intractable rectal cancer pain in palliative care

    Zaporowska-Stachowiak I

    2014-10-01

    Full Text Available Iwona Zaporowska-Stachowiak,1,2 Grzegorz Kowalski,3 Jacek Łuczak,2 Katarzyna Kosicka,4 Aleksandra Kotlinska-Lemieszek,3 Maciej Sopata,3 Franciszek Główka4 1Chair and Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland; 2Palliative Medicine In-patient Unit, University Hospital of Lord's Transfiguration, Poznan University of Medical Sciences, Poznan, Poland; 3Palliative Medicine Chair and Department, Poznan University of Medical Sciences, Poznan, Poland; 4Department of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, Poznan, Poland Background: Unacceptable adverse effects, contraindications to and/or ineffectiveness of World Health Organization step III "pain ladder" drugs causes needless suffering among a population of cancer patients. Successful management of severe cancer pain may require invasive treatment. However, a patient's refusal of an invasive procedure necessitates that clinicians consider alternative options. Objective: Intrathecal bupivacaine delivery as a viable treatment of intractable pain is well documented. There are no data on rectal bupivacaine use in cancer patients or in the treatment of cancer tenesmoid pain. This study aims to demonstrate that bupivacaine administered rectally could be a step in between the current treatment options for intractable cancer pain (conventional/conservative analgesia or invasive procedures, and to evaluate the effect of the mode of administration (intrathecal versus rectal on the bupivacaine plasma concentration.Cases: We present two Caucasian, elderly inpatients admitted to hospice due to intractable rectal/tenesmoid pain. The first case is a female with vulvar cancer, and malignant infiltration of the rectum/vagina. Bupivacaine was used intrathecally (0.25–0.5%, 1–2 mL every 6 hours. The second case is a female with ovarian cancer and malignant rectal infiltration. Bupivacaine was adminstered rectally (0.05–0.1%, 100 m

  10. Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy: a dose-volume analysis

    To evaluate the impact of four different rectum contouring techniques and rectal toxicities in patients with treated with 3D conformal radiotherapy (3DCRT). Clinical and dosimetric data were evaluated for 94 patients who received a total dose 3DCRT of 70 Gy, and rectal doses were compared in four different rectal contouring techniques: the prostate-containing CT sections (method 1); 1 cm above and below the planning target volume (PTV) (method 2); 110 mm starting from the anal verge (method 3); and from the anal verge to the sigmoid flexure (method 4). The percentage of rectal volume receiving RT doses (30–70 Gy) and minimum, mean rectal doses were assessed. Median age was 69 years. Percentage of rectal volume receiving high doses (≥ 70 Gy) were higher with the techniques that contoured smaller rectal volumes. In methods 2 and 3, the percentage of rectal volume receiving ≥ 70 Gy was significantly higher in patients with than without rectal bleeding (method 2: 30.8% vs. 22.5%, respectively (p = 0.03); method 3: 26.9% vs. 18.1%, respectively (p = 0.006)). Mean rectal dose was significant predictor of rectal bleeding only in method 3 (48.8 Gy in patients with bleeding vs. 44.4 Gy in patients without bleeding; p = 0.02). Different techniques of rectal contouring significantly influence the calculation of radiation doses to the rectum and the prediction of rectal toxicity. Rectal volume receiving higher doses (≥ 70 Gy) and mean rectal doses may significantly predict rectal bleeding for techniques contouring larger rectal volumes, as was in method 3

  11. Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy: a dose-volume analysis

    Yavuz Melek

    2009-05-01

    Full Text Available Abstract Background To evaluate the impact of four different rectum contouring techniques and rectal toxicities in patients with treated with 3D conformal radiotherapy (3DCRT. Methods Clinical and dosimetric data were evaluated for 94 patients who received a total dose 3DCRT of 70 Gy, and rectal doses were compared in four different rectal contouring techniques: the prostate-containing CT sections (method 1; 1 cm above and below the planning target volume (PTV (method 2; 110 mm starting from the anal verge (method 3; and from the anal verge to the sigmoid flexure (method 4. The percentage of rectal volume receiving RT doses (30–70 Gy and minimum, mean rectal doses were assessed. Results Median age was 69 years. Percentage of rectal volume receiving high doses (≥ 70 Gy were higher with the techniques that contoured smaller rectal volumes. In methods 2 and 3, the percentage of rectal volume receiving ≥ 70 Gy was significantly higher in patients with than without rectal bleeding (method 2: 30.8% vs. 22.5%, respectively (p = 0.03; method 3: 26.9% vs. 18.1%, respectively (p = 0.006. Mean rectal dose was significant predictor of rectal bleeding only in method 3 (48.8 Gy in patients with bleeding vs. 44.4 Gy in patients without bleeding; p = 0.02. Conclusion Different techniques of rectal contouring significantly influence the calculation of radiation doses to the rectum and the prediction of rectal toxicity. Rectal volume receiving higher doses (≥ 70 Gy and mean rectal doses may significantly predict rectal bleeding for techniques contouring larger rectal volumes, as was in method 3.

  12. Differences in microbial signatures between rectal mucosal biopsies and rectal swabs

    Araújo-Pérez, Félix; Amber N McCoy; Okechukwu, Charles; Carroll, Ian M.; Smith, Kevin M.; Jeremiah, Kim; Sandler, Robert S.; Asher, Gary N; Keku, Temitope O

    2012-01-01

    There is growing evidence the microbiota of the large bowel may influence the risk of developing colorectal cancer as well as other diseases including type-1 diabetes, inflammatory bowel diseases and irritable bowel syndrome. Current sampling methods to obtain microbial specimens, such as feces and mucosal biopsies, are inconvenient and unappealing to patients. Obtaining samples through rectal swabs could prove to be a quicker and relatively easier method, but it is unclear if swabs are an ad...

  13. Benign (solitary) ulcer of the rectum - another cause for rectal stricture

    Chapa, H.J.; Smith, H.J.; Dickinson, T.A.

    1981-01-15

    Benign rectal ulcer syndrome is an uncommon cause of lower gastrointestinal bleeding. Patients may present with mild, often recurrent, rectal bleeding frequently ascribed to hemorrhoids. Barium enema may be normal during the early, nonulcerative phase of proctitis. Single (or multiple) ulcers with or without rectal stricture are the hallmarks of the radiographic diagnosis. Radiologic demonstration of the ulcer(s) is not required, however, for the diagnosis. Benign rectal ulcer should be included in the differential diagnosis of benign-appearing rectal strictures.

  14. Significance of thermoradiotherapy for rectal cancer

    Ike, Hideyuki; Fukano, Masahiko; Yamaguchi, Sigeki [Yokohama City Univ. (Japan). School of Medicine] [and others

    1997-05-01

    In patients with rectal cancer, results of 27 cases receiving thermoradiotherapy and of 68 cases, radiotherapy before operation were compared with those of 119 cases receiving expanded radical operation. Radiotherapy was done with 10 MV X-ray generated by linear-accelerator at 2.0 Gy x 5/week and 60 Gy in total. Hyperthermotherapy was performed with the capacitive heating method with 8 MHz radiofrequency (Thermotoron RF8) twice/week x 5. Every thermotherapy was done for 40 min at 42degC-43degC within 1 hr after the radiotherapy. Good results were observed in cases whose cancer was disappeared by either preoperative therapy. However, results in survival and recurrence rates were not always improved when compared with those receiving surgery alone. (K.H.)

  15. 'Microerosions' in rectal biopsies in Crohn's disease

    Poulsen, Steen Seier

    1984-01-01

    Small (less than 1 mm), superficial erosions ('microerosions') have been observed stereo-microscopically in surface-stained rectal biopsies in Crohn's disease (CD). Biopsy specimens from 97 patients with CD, 225 with ulcerative colitis (UC), and a control material of 161 patients were investigated...... exclusively. Granulomas were identified in 62% of the biopsies with microerosions and by examination of two consecutive biopsies from each of these patients, in 85% indicating a positive correlation. In patients with microerosions and a primary diagnosis of UC, granulomas were found in 38% and by examination...... of two biopsies in 54%. Patients with granulomas and a few other patients were reclassified as CD, but there still remained some patients with microerosions, who most probably had UC. In conclusion, microerosions are observed mainly in CD with colonic involvement. There is a high incidence of...

  16. [Organ preserving strategies for rectal cancer treatment].

    Vendrely, V; Denost, Q; Amestoy, F; Célérier, B; Smith, D; Rullier, A; Rullier, É

    2015-10-01

    For rectal cancers, the current standard of care consists of chemoradiation followed by radical surgery with total mesorectal excision. Oncologic results are good, especially regarding local recurrence rates, but at the cost of high morbidity rates and poor anorectal, urinary and sexual function results. Since chemoradiation yields 15 to 25% pathological complete response, the role of radical surgery is questioned for patients presenting with good response after chemoradiation and two organ preservation strategies have been offered: watch and wait strategy and local excision strategy. The aim of this review is to give the results of organ preservation after chemoradiotherapy series and to highlight different questions regarding initial patient's selection, complete clinical response definition, risk of mesorectal nodal involvement, follow-up modalities as well as oncologic and functional results. PMID:26278990

  17. Expression and clinical significance of cellular prion protein in rectal cancer and adenoma

    Wei-ping LI

    2015-07-01

    Full Text Available Objective To determine the expressions of cellular prion protein (PrPC in normal rectal mucosa, rectal adenoma and rectal carcinoma tissues, and to study the relationship of PrPC with development and progression of rectal carcinoma. Methods Immunohistochemical method (SP method was used to determine the expressions of PrPC in rectal carcinoma (60 samples, rectal adenoma (20 samples and normal rectal mucosa (20 samples, and the correlations between the expression of PrPC in rectal carcinoma tissue, and clinical pathological parameters including sex, tumor differentiation, clinical stages, lymph node metastasis, etc. were analyzed. Results PrPC was expressed in normal rectal mucosa, rectal adenoma and rectal carcinoma tissues. The positive rate of PrPC expression in rectal carcinoma (65% was significantly higher than that in rectal adenoma (35% and normal rectal mucosa (15% with statistical significance (P0.05. Conclusion PrPC may play an important role in the process of development, progression and metastasis of rectal carcinoma. DOI: 10.11855/j.issn.0577-7402.2015.07.12

  18. Efficiency of Non-Contrast-Enhanced Liver Imaging Sequences Added to Initial Rectal MRI in Rectal Cancer Patients.

    Gene-hyuk Kwon

    Full Text Available The purpose of this study was to estimate the value of addition of liver imaging to initial rectal magnetic resonance imaging (MRI for detection of liver metastasis and evaluate imaging predictors of a high risk of liver metastasis on rectal MRI.We enrolled 144 patients who from October 2010 to May 2013 underwent rectal MRI with T2-weighted imaging (T2WI and diffusion-weighted imaging (DWI (b values = 50, 500, and 900 s/mm2 of the liver and abdominopelvic computed tomography (APCT for the initial staging of rectal cancer. Two reviewers scored the possibility of liver metastasis on different sets of liver images (T2WI, DWI, and combined T2WI and DWI and APCT and reached a conclusion by consensus for different analytic results. Imaging features from rectal MRI were also analyzed. The diagnostic performances of CT and an additional liver scan to detect liver metastasis were compared. Multivariate logistic regression to determine independent predictors of liver metastasis among rectal MRI features and tumor markers was performed. This retrospective study was approved by the Institutional Review Board, and the requirement for informed consent was waived.All sets of liver images were more effective than APCT for detecting liver metastasis, and DWI was the most effective. Perivascular stranding and anal sphincter invasion were statistically significant for liver metastasis (p = 0.0077 and p = 0.0471, while extramural vascular invasion based on MRI (mrEMVI was marginally significant (p = 0.0534.The addition of non-contrast-enhanced liver imaging, particularly DWI, to initial rectal MRI in rectal cancer patients could facilitate detection of liver metastasis without APCT. Perivascular stranding, anal sphincter invasion, and mrEMVI detected on rectal MRI were important imaging predictors of liver metastasis.

  19. Absorption spectra of CsNd(MoO4)2 and CsGd(MoO4)2-Nd3+ crystals in strong magnetic fields

    The comparison of the electronic structure of Nd3+ in CsNd(MoO4)2 and CsGd(MoO4)2 - Nd3+ crystals is made. It is established that in these crystals the activator centers, mainly, of the certain type with the symmetry of the local environment C2 are formed. The absorption spectra of self-activated CsNd(MoO4)2 crystal differ from spectra of CsGd(MoO4)2 - Nd3+ by the presence of the vibrating structure. The Stark splittings of energy levels of Nd3+ in the investigated crystalline matrices are more sensitive to the environment effect than the Zeeman ones. The ground state of Nd3+ ion in CsNd(MoO4)2 and CsGd(MoO4)2 molybdates is characterized by the similar values of g-factors

  20. Comparative analysis of effectiveness of treatment with anti-TB drugs of the 1st and 2nd lines for children and adolescents with multidrug resistant tuberculosis

    Tleukhan Abildaev

    2012-05-01

    Full Text Available The paper shows results of study on comparative treatment effectiveness in children and adolescents with from multi drug resistant tuberculosis MDR TB (2000-2008 treated with anti-TB drugs of the 2nd line (80 patients and 1st line (80 patients in the Kazakhstan. It was stated in patients with MDR TB that outcomes of treatment were successful in 91.2%, but relapse development of TB disease occurred in 12.7% of cases, and 5 (6.2% patients died (P ≤0.05. Thus, patients with MDR TB need to be treated with anti-TB drugs of the 2nd line accordingly to their DST.

  1. Late Side Effects and Quality of Life After Radiotherapy for Rectal Cancer

    Purpose: There is little knowledge on long-term morbidity after radiotherapy (50 Gy) and total mesorectal excision for rectal cancer. Therefore, late effects on bowel, anorectal, and urinary function, and health-related quality of life (QoL), were studied in a national cohort (n = 535). Methods and Materials: All Norwegian patients who received pre- or postoperative (chemo-)radiotherapy for rectal cancer from 1993 to 2003 were identified. Patients treated with surgery alone served as controls. Patients were without recurrence or metastases. Bowel and urinary function was scored with the LENT SOMA scale and the St. Marks Score for fecal incontinence and QoL with the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30). Results: Median time since surgery was 4.8 years. Radiation-treated (RT+) patients (n = 199) had increased bowel frequency compared with non-radiation-treated (RT-) patients (n = 336); 19% vs. 6% had more than eight daily bowel movements (p < 0.001). In patients without stoma, a higher proportion of RT+ (n = 69) compared with RT- patients (n = 240), were incontinent for liquid stools (49% vs. 15%, p < 0.001), needed a sanitary pad (52% vs. 13%, p < 0.001), and lacked the ability to defer defecation (44% vs. 16%, p < 0.001). Daily urinary incontinence occurred more frequently after radiotherapy (9% vs. 2%, p = 0.001). Radiation-treated patients had worse social function than RT- patients, and patients with fecal or urinary incontinence had impaired scores for global quality of life and social function (p < 0.001). Conclusions: Radiotherapy for rectal cancer is associated with considerable long-term effects on anorectal function, especially in terms of bowel frequency and fecal incontinence. RT+ patients have worse social function, and fecal incontinence has a negative impact on QoL.

  2. The Quality-of-Life Effects of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer

    Herman, Joseph M., E-mail: jherma15@jhmi.edu [Department of Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland (United States); Narang, Amol K. [Department of Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland (United States); Griffith, Kent A. [Department of Biostatistics, University of Michigan School of Medicine, Ann Arbor, Michigan (United States); Zalupski, Mark M. [Department of Hematology Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan (United States); Reese, Jennifer B. [Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland (United States); Gearhart, Susan L. [Department of Medical Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland (United States); Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland (United States); Azad, Nolifer S. [Department of Medical Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland (United States); Chan, June; Olsen, Leah [Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan (United States); Efron, Jonathan E. [Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland (United States); Lawrence, Theodore S.; Ben-Josef, Edgar [Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan (United States)

    2013-01-01

    Purpose: Existing studies that examine the effect of neoadjuvant chemoradiation (CRT) for locally advanced rectal cancer on patient quality of life (QOL) are limited. Our goals were to prospectively explore acute changes in patient-reported QOL endpoints during and after treatment and to establish a distribution of scores that could be used for comparison as new treatment modalities emerge. Methods and Materials: Fifty patients with locally advanced rectal cancer were prospectively enrolled at 2 institutions. Validated cancer-specific European Organization for Research and Treatment of Cancer (EORTC QLQ-CR30) and colorectal cancer-specific (EORTC QLQ-CR38 and EORTC QLQ-CR 29) QOL questionnaires were administered to patients 1 month before they began CRT, at week 4 of CRT, and 1 month after they had finished CRT. The questionnaires included multiple symptom scales, functional domains, and a composite global QOL score. Additionally, a toxicity scale was completed by providers 1 month before the beginning of CRT, weekly during treatment, and 1 month after the end of CRT. Results: Global QOL showed a statistically significant and borderline clinically significant decrease during CRT (-9.50, P=.0024) but returned to baseline 1 month after the end of treatment (-0.33, P=.9205). Symptoms during treatment were mostly gastrointestinal (nausea/vomiting +9.94, P<.0001; and diarrhea +16.67, P=.0022), urinary (dysuria +13.33, P<.0001; and frequency +11.82, P=.0006) or fatigue (+16.22, P<.0001). These symptoms returned to baseline after therapy. However, sexual enjoyment (P=.0236) and sexual function (P=.0047) remained persistently diminished after therapy. Conclusions: Rectal cancer patients undergoing neoadjuvant CRT may experience a reduction in global QOL along with significant gastrointestinal and genitourinary symptoms during treatment. Moreover, provider-rated toxicity scales may not fully capture this decrease in patient-reported QOL. Although most symptoms are transient

  3. Correlations of organic chemistry study of the 2nd year “Pharmacy” faculty students of specialty “Technology of perfume-cosmetic preparations”

    Antypenko, L. M.; Kandybey, K. I.; Kovalenko, S. I.

    2015-01-01

    In order to analyze the organic chemistry study for 2nd year students of specialty “Technology of perfume-cosmetic preparations” in Zaporizhzhya State Medical University, correlations between preparation time for the theoretical part of the classes, for computer testing and its percentage, the impact of the organic chemistry at school to university mark, and in general for all disciplines attestation, using Pearson and Spearman correlations, Kolmogorov-Smirn...

  4. An intensive Post Event Campaign (IPEC) on the extreme flash flood which affected the Starzel river (Germany) on the 2nd of June 2008

    Gaume, Eric

    2009-01-01

    On the 2nd of June 2008 in the evening, the Zollernabkreis region, located 50 kilometers South from Stuttgart (Germany), was affected by extreme thunderstorms which induced large flash floods. The most severely affected area appeared to be the upper Starzel river catchment (130 km2) where the extraordinary flood caused large damages in two towns (Hechingen and Jungingen) and killed 3 people. The data collected immediately after the flood event are impressive : 75 mm of rainfall accumulated wi...

  5. A Soliton Hierarchy Associated with a Spectral Problem of 2nd Degree in a Spectral Parameter and Its Bi-Hamiltonian Structure

    Yuqin Yao

    2016-01-01

    Full Text Available Associated with so~(3,R, a new matrix spectral problem of 2nd degree in a spectral parameter is proposed and its corresponding soliton hierarchy is generated within the zero curvature formulation. Bi-Hamiltonian structures of the presented soliton hierarchy are furnished by using the trace identity, and thus, all presented equations possess infinitely commuting many symmetries and conservation laws, which implies their Liouville integrability.

  6. Rectal absorption of homatropine [14C] methylbromide in the rat

    Homatropine [14C]methylbromide (HMB-14C) was administered to rats by intramuscular injection, oral gavage and rectal suppository. Plasma concentrations of 14C were measured over the subsequent 12 h. Peak plasma concentrations were higher and achieved more rapidly after rectal administration than by other routes whether HMB-14C was administered in a water-soluble suppository base or in aqueous solution. Twelve h after the suppositories were inserted and retained 28% of the 14C had been excreted in the urine while 56% remained in the large intestine. Unlabelled HMB, given in rectal suppositories to anaesthetized rats, caused prompt blockade of the effects of vagal stimulation on pulse rate and of intravenous acetylcholine on blood pressure. These results confirm the rapid rectal absorption of the drug. (author)

  7. Postoperative adjuvant chemotherapy in rectal cancer operated for cure

    Petersen, Sune Høirup; Harling, Henrik; Kirkeby, Lene Tschemerinsky;

    2012-01-01

    Colorectal cancer is one of the most common types of cancer in the Western world. Apart from surgery - which remains the mainstay of treatment for resectable primary tumours - postoperative (i.e., adjuvant) chemotherapy with 5-fluorouracil (5-FU) based regimens is now the standard treatment...... in Dukes´ C (TNM stage III) colon tumours i.e. tumours with metastases in the regional lymph nodes but no distant metastases. In contrast, the evidence for recommendations of adjuvant therapy in rectal cancer is sparse. In Europe it is generally acknowledged that locally advanced rectal tumours receive...... preoperative (i.e., neoadjuvant) downstaging by radiotherapy (or chemoradiotion), whereas in the US postoperative chemoradiotion is considered the treatment of choice in all Dukes´ C rectal cancers. Overall, no universal consensus exists on the adjuvant treatment of surgically resectable rectal carcinoma...

  8. [Rectal prolapse revealing a tumor: The role of abdominal ultrasound].

    Bequet, E; Stiennon, L; Lhomme, A; Piette, C; Hoyoux, C; Rausin, L; Guidi, O

    2016-07-01

    Rectal prolapse is rare in children and usually benign. However, there are various diseases that can be associated with it, such as cystic fibrosis or other causes of increased abdominal pressure. Here, we review the various underlying conditions that pediatricians or pediatric gastroenterologists should consider in the case of rectal prolapse. We report on three cases of children with a rectal prolapse and intra-abdominal tumors. Current recommendations and practice do not include a systematic check via abdominal imaging in cases of rectal prolapse. However, in some situations, imaging is indicated to detect a possible expansive process. Thus, in the presence of recurrent prolapse or of associated urinary or neurological signs, imaging is justified so as to allow for an early diagnosis and treatment of these neoplasms. Given its lack of radiation exposure and good sensitivity in children, ultrasound imaging is the first choice. PMID:27265581

  9. Rectal bacteriotherapy for recurrent Clostridium difficile-associated diarrhoea

    Tvede, M; Tinggaard, M; Helms, M

    2015-01-01

    Clostridium difficile infection is one of the most common nosocomial infections. Among other alternatives to standard treatment with vancomycin for recurrent infection are faecal microbiota transplantation and rectal bacteriotherapy with a fixed mixture of intestinal bacterial strains isolated from...

  10. Laparoscopic resection for low rectal cancer: evaluation of oncological efficacy.

    Moran, Diarmaid C

    2011-09-01

    Laparoscopic resection of low rectal cancer poses significant technical difficulties for the surgeon. There is a lack of published follow-up data in relation to the surgical, oncological and survival outcomes in these patients.

  11. PREFACE: The 2nd International Conference on Geological, Geographical, Aerospace and Earth Sciences 2014 (AeroEarth 2014)

    Lumban Gaol, Ford; Soewito, Benfano

    2015-01-01

    The 2nd International Conference on Geological, Geographical, Aerospace and Earth Sciences 2014 (AeroEarth 2014), was held at Discovery Kartika Plaza Hotel, Kuta, Bali, Indonesia during 11 - 12 October 2014. The AeroEarth 2014 conference aims to bring together researchers and engineers from around the world. Through research and development, earth scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. Earth provides resources and the exact conditions to make life possible. However, with the advent of technology and industrialization, the Earth's resources are being pushed to the brink of depletion. Non-sustainable industrial practices are not only endangering the supply of the Earth's natural resources, but are also putting burden on life itself by bringing about pollution and climate change. A major role of earth science scholars is to examine the delicate balance between the Earth's resources and the growing demands of industrialization. Through research and development, earth scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting Conference Program as well as the invited and plenary speakers. This year, we received 98 papers and after rigorous review, 17 papers were accepted. The participants come from eight countries. There are four Parallel Sessions and two invited Speakers. It is an honour to present this volume of IOP Conference Series: Earth and Environmental Science (EES) and we deeply thank the authors for their enthusiastic and high-grade contributions. Finally, we would like to thank the conference chairmen, the members of the steering committee, the organizing committee

  12. Higher rectal temperatures in co-sleeping infants.

    Tuffnell, C S; Petersen, S A; Wailoo, M P

    1996-01-01

    The effect on deep body temperature of infants co-sleeping (with either or both parents) is investigated in this case control study. Overnight continuous recordings of rectal temperature were made from 34 babies co-sleeping with one or both parents throughout the night and 34 infants matched for age, feeding regimen, parental smoking, thermal environment, sleeping position, and sex who slept alone. The co-sleeping infants had significantly higher rectal temperatures from two hours after bedti...

  13. RECTAL DUPLICATION CYST IN PREVIOUS ANORECTAL MALFORMATION AND DOWN SYNDROME

    A. Burgio

    2012-12-01

    Full Text Available Gastrointestinal (GI tract duplications are rare congenital malformations. Most of them occur in the ileum and only 1-5%, of all duplication, were in the rectum. Different clinical features including chronic constipation, rectal prolapsed or polips. We report on a 4-years-old girl with Down syndrome and anorectal malformation (ARM who was found to have a rectal duplication cyst.

  14. Direct costs of radiotherapy for rectal cancer: a microcosting study

    Hanly, Paul; Céilleachair, Alan Ó; Skally, Máiréad; O’Neill, Ciaran; Sharp, Linda

    2015-01-01

    Background Radiotherapy provides significant benefits in terms of reducing risk of local recurrence and death from rectal cancer. Despite this, up-to-date cost estimates for radiotherapy are lacking, potentially inhibiting policy and decision-making. Our objective was to generate an up-to-date estimate of the cost of traditional radiotherapy for rectal cancer and model the impact of a range of potential efficiency improvements. Methods Microcosting methods were used to estimate total direct r...

  15. Functional MR imaging for response prediction in rectal cancer treatment

    Intven, M.P.W.

    2015-01-01

    The standard of care treatment for locally advanced rectal cancer is neoadjuvant chemoradiation followed by total mesorectal excision. In recent years, organ-sparing treatments, instead of standard total mesorectal excision, are gradually introduced in the treatment of rectal cancer for patients with good response after neoadjuvant therapy. However, patient selection for organ-sparing treatments is still challenging as no optimal restaging modality is available after neoadjuvant chemoradiatio...

  16. Plasma concentrations of clonazepam after single rectal administration.

    Rylance, G W; Poulton, J; Cherry, R C; Cullen, R E

    1986-01-01

    Clonazepam was administered rectally to six children aged 1.4 to 4.7 years in a dose of 0.05 mg/kg and to five children aged 1.4 to 4.1 years in a dose of 0.1 mg/kg. Plasma concentrations indicate that it is rapidly absorbed, and it may therefore be an alternative to rectal administration of diazepam in continuing convulsions.

  17. MRI in children following surgery for anal and rectal atresia

    MRI of the pelvis was performed in 17 children following surgical correction of anal and rectal atresias and in five children without ano-rectal malformations. A muscle score was used to characterize the muscles of the pelvic floor and their relationship to the rectum. There was close agreement between the MRI muscle score and clinical continence. MRI provided additional information that should improve continence following conservative and surgical treatment. (orig.)

  18. Ultrastructural pathology of the rectal mucosa in Shigella dysentery.

    Mathan, M M; Mathan, V I

    1986-01-01

    Colonocyte damage in the rectal mucosa in shigellosis is the result of bacterial invasion and leads to ulceration. Additional factors in colonocyte damage may be the Shigella cytotoxin and, especially in colonic crypt cells, bacterial endotoxin. A vascular lesion was present in the lamina propria of the rectal mucosa, which resembled endothelial damage secondary to bacterial endotoxins. In patients with longer duration of symptoms, relative vascular insufficiency, activated lymphocytes, eosin...

  19. Congenital cystic polypoid rectal hamartoma in a newborn foal.

    Dunkel, B; Shokek, A B; Wilkins, P A

    2004-11-01

    A neonatal foal with signs of rectal bleeding was diagnosed with an intraluminal rectal mass and intussusception on surgical exploration of the abdomen. Histologically, the mass consisted of cystic spaces lined by simple columnar epithelium with numerous goblet cells and was surrounded by thin bands of smooth muscle in a myxomatous stroma. Although the mass shared similarities with retrorectal cystic hamartoma (tailgut cyst) and juvenile polyps, described in human medicine, location and histologic findings were not entirely consistent with either condition. PMID:15557082

  20. European structuralism

    Willems, Klaas

    2014-01-01

    European structuralism is a paradigm for the study of language developed by prominent European linguists during the inter-war period and the first decades after World War II that radically rejected the prevailing atomism of 19th century (particularly neo-grammarian) linguistics and language psychology.

  1. Selective Europeanization

    Hoch Jovanovic, Tamara; Lynggaard, Kennet

    2014-01-01

    political contexts at the European level. We further show how the “translation” of international norms to a domestic context has worked to reinforce the original institutional setup, dating back to the mid-1950s. The translation of European-level minority policy developed in the 1990s and 2000s works most...

  2. The rectal cancer microRNAome - microRNA expression in rectal cancer and matched normal mucosa

    Gaedcke, Jochen; Grade, Marian; Camps, Jordi;

    2012-01-01

    PURPOSE: miRNAs play a prominent role in a variety of physiologic and pathologic biologic processes, including cancer. For rectal cancers, only limited data are available on miRNA expression profiles, whereas the underlying genomic and transcriptomic aberrations have been firmly established. We...... therefore, aimed to comprehensively map the miRNA expression patterns of this disease. EXPERIMENTAL DESIGN: Tumor biopsies and corresponding matched mucosa samples were prospectively collected from 57 patients with locally advanced rectal cancers. Total RNA was extracted, and tumor and mucosa mi......RNA expression profiles were subsequently established for all patients. The expression of selected miRNAs was validated using semi-quantitative real-time PCR. RESULTS: Forty-nine miRNAs were significantly differentially expressed (log(2)-fold difference >0.5 and P < 0.001) between rectal cancer and normal rectal...

  3. Rectal toxicity after intensity modulated radiotherapy for prostate cancer: Which rectal dose volume constraints should we use?

    Background: To define rectal dose volume constraints (DVC) to prevent ⩾grade2 late rectal toxicity (LRT) after intensity modulated radiotherapy (IMRT) for prostate cancer (PC). Material and methods: Six hundred thirty-seven PC patients were treated with primary (prostate median dose: 78 Gy) or postoperative (prostatic bed median dose: 74 Gy (adjuvant)–76 Gy (salvage)) IMRT while restricting the rectal dose to 76 Gy, 72 Gy and 74 Gy respectively. The impact of patient characteristics and rectal volume parameters on ⩾grade2 LRT was determined. DVC were defined to estimate the 5% and 10% risk of developing ⩾grade2 LRT. Results: The 5-year probability of being free from ⩾grade2 LRT, non-rectal blood loss and persisting symptoms is 88.8% (95% CI: 85.8–91.1%), 93.4% (95% CI: 91.0–95.1%) and 94.3% (95% CI: 92.0–95.9%) respectively. There was no correlation with patient characteristics. All volume parameters, except rectal volume receiving ⩾70 Gy (R70), were significantly correlated with ⩾grade2 LRT. To avoid 10% and 5% risk of ⩾grade2 LRT following DVC were derived: R40, R50, R60 and R65 <64–35%, 52–22%, 38–14% and 5% respectively. Conclusion: Applying existing rectal volume constraints resulted in a 5-year estimated risk of developing late ⩾grade2 LRT of 11.2%. New rectal DVC for primary and postoperative IMRT planning of PC patients are proposed. A prospective evaluation is needed

  4. Alternative procedure to shorten rectal barostat procedure for the assessment of rectal compliance and visceral perception: a feasibility study

    Vanhoutvin, S.A.L.W.; Troost, F. J; Kilkens, T. O. C.; Lindsey, P. J.; Jonkers, D.M.A.E.; Venema, K.; Masclee, A.; Brummer, R-J M

    2012-01-01

    Background Barostat methodology is widely used for assessing visceral perception. Different barostat protocols are described with respect to the measurement of rectal compliance and visceral perception. The choice of protocols affects the duration, which is normally 60–90 min, and accuracy of the procedure. This study aimed to shorten the procedure by using the semi-random distension protocol for both compliance and visceral perception measurement and a correction based on rectal capacity (RC...

  5. Alternative procedure to shorten rectal barostat proecure for the assessment of rectal compliance and visceral perception: a feasibility study

    Vanhoutvin, S.A.; Troost, F. J; Kilkens, T.O.; Lindsey, P. J.; Jonkers, D.M.; Venema, K.; Masclee, A.; Brummer, R J

    2012-01-01

    BACKGROUND: Barostat methodology is widely used for assessing visceral perception. Different barostat protocols are described with respect to the measurement of rectal compliance and visceral perception. The choice of protocols affects the duration, which is normally 60-90 min, and accuracy of the procedure. This study aimed to shorten the procedure by using the semi-random distension protocol for both compliance and visceral perception measurement and a correction based on rectal capacity (R...

  6. Limited segmental rectal resection in the treatment of deeply infiltrating rectal endometriosis: 10 years’ experience from a tertiary referral unit

    English, James, Jr.; Sajid, Muhammad S; Lo, Jenney; Hudelist, Guy; Baig, Mirza K.; Miles, William A.

    2014-01-01

    Background. The management of symptomatic rectal endometriosis is a challenging condition that may necessitate limited stripping or limited segmental anterior rectal resection (LSARR) depending upon the extent and severity of the disease. Objective. To report the efficacy of LSARR in terms of pain, quality of life and short- and long-term complications—in particular, those pertaining to bowel function. Methods. The case notes of all patients undergoing LSARR were reviewed. The analysed variab...

  7. Geometric modeling, functional parameter calculation, and visualization of the in-vivo distended rectal wall

    Haider, Clifton R.; Manduca, Armando; Camp, Jon J.; Fletcher, Joel G.; Robb, Richard A.; Bharucha, Adil E.

    2006-03-01

    The rectum can distend to accommodate stool, and contracts in response to distention during defecation. Rectal motor dysfunctions are implicated in the pathophysiology of functional defecation disorders and fecal incontinence. These rectal motor functions can be studied by intra-luminal measurements of pressure by manometry, or combined with volume during rectal balloon distention. Pressure-volume (p-v) relationships provide a global index of rectal mechanical properties. However, balloon distention alone does not measure luminal radius or wall thickness, which are necessary to compute wall tension and stress respectively. It has been suggested that the elastic modulus, which is the linear slope of the stress-strain relationship, is a more accurate measure of wall stiffness. Also, measurements of compliance may not reflect differences in rectal diameter between subjects prior to inflation, and imaging is necessary to determine if, as has been suggested, rectal pressure-volume relationships are affected by extra-rectal structures. We have developed a technique to measure rectal stress:strain relationships in humans, by simultaneous magnetic resonance imaging (MRI) during rectal balloon distention. After a conditioning distention, a rectal balloon was distended with water from 0 to 400 ml in 50 ml steps, and imaged at each step with MRI. The fluid filled balloon was segmented from each volume, the phase-ordered binary volumes were transformed into a geometric characterization of the inflated rectal surface. Taken together with measurements of balloon pressure and of rectal wall thickness, this model of the rectal surface was used to calculate regional values of curvature, tension, strain, and stress for the rectum. In summary, this technique has the unique ability to non-invasively measure the rectal stress:strain relationship and also determine if rectal expansion is limited by extra-rectal structures. This functional information allows the direct clinical analysis

  8. Preserving the superior rectal artery in laparoscopic sigmoid resection for complete rectal prolapse.

    Bergamaschi, R; Lovvik, K; Marvik, R

    2004-01-01

    Sigmoid resection is indicated in the treatment of complete rectal prolapse (CRP) in patients with prolonged colorectal transit time (CTT). Its use however has been limited due to fear of anastomotic leakage. This study challenges the current practice of dividing the mesorectum by prospectively evaluating the impact of sparing the superior rectal artery (SRA) on leak rates after laparoscopic sigmoid resection (LSR) for CRP. During 30 months data on 33 selected patients with CRP were prospectively collected. Three patients were withdrawn from the analysis, as they had neither resection nor anastomosis. Twenty-nine women and one man (median age 55 range 21-83 years) underwent LSR with preservation of SRA for a median CRP of 8 (3-15) cm. There were 20 ASA I and 10 ASA II patients. Ten patients had undergone previous surgery. Four patients complained of dyschezia, whereas incontinence was present in 26 patients. Anal ultrasound showed isolated internal sphincter defects in two patients. Four young adults (21-32 years) had normal CTT, whereas 26 older patients had a median CTT of 5 (4-6) days. Defecography demonstrated 10 enteroceles, two sigmoidoceles, and one rectal hernia through the levator ani muscle. Mortality was nil. Median operating room time was 180 (120-330) min, suprapubic incision length 5 (3-7) cm, estimated blood loss 150 (50-500) ml, specimen length 20 (12-45) cm, solid food resumption 3 (1-6) days, and length of stay 4.5 (2-7) days. Thirty-day complications were not related to anastomosing and occurred in 20% of the patients. Although the evidence provided by the present study suggests that sparing SRA has a favorable impact on anastomotic leak rates, these nonrandomized results need further evaluation. The division of the mesorectum at the rectosigmoid junction seems not necessary, and its sparing should therefore be considered as it may contain anastomotic leak rates. PMID:15771289

  9. Early results of quality of life for curatively treated rectal cancers in Chinese patients with EORTC QLQ-CR29

    To assess the quality of life in curatively treated patients with rectal cancer in a prospectively collected cohort. Patients with stage I-III rectal cancer who were treated curatively in a single institution were accrued prospectively. Quality of life was assessed by use of the European Organization for Research and Treatment of Cancer questionnaire module for all cancer patients (QLQ-C30) and for colorectal cancer patients (QLQ-CR29). Quality of life among different treatment modalities and between stoma and nonstoma patients was evaluated in all patients. A total of 154 patients were assessed. The median time of completion for the questionnaires was 10 months after all the treatments. For patients with different treatment modalities, faecal incontinence and diarrhea were significantly higher in radiation group (p = 0.002 and p = 0.001, respectively), and no difference in male or female sexual function was found between radiation group and non-radiation group. For stoma and nonstoma patients, the QLQ-CR29 module found the symptoms of Defaecation and Embarrassment with Bowel Movement were more prominent in stoma patients, while no difference was detected in scales QLQ-C30 module. Our study provided additional information in evaluating QoL of Chinese rectal cancer patients with currently widely used QoL questionnaires. As a supplement to the QLQ-C30, EORTC QLQ-CR29 is a useful questionnaire in evaluating curatively treated patients with rectal cancer. Bowel dysfunction (diarrhea and faecal incontinence) was still the major problem compromising QoL in patients with either pre- or postoperative chemoradiotherapy

  10. European Whiteness?

    Blaagaard, Bolette

    2008-01-01

    Born out of the United States’ (U.S.) history of slavery and segregation and intertwined with gender studies and feminism, the field of critical whiteness studies does not fit easily into a European setting and the particular historical context that entails. In order for a field of European...... critical whiteness studies to emerge, its relation to the U.S. theoretical framework, as well as the particularities of the European context need to be taken into account.. The article makes a call for a multi-layered approach to take over from the identity politics so often employed in the fields of U...

  11. Results of Neoadjuvant Short-Course Radiation Therapy Followed by Transanal Endoscopic Microsurgery for T1-T2 N0 Extraperitoneal Rectal Cancer

    Purpose: This study was undertaken to assess the short-term outcomes of neoadjuvant short-course radiation therapy (SCRT) followed by transanal endoscopic microsurgery (TEM) for T1-T2 N0 extraperitoneal rectal cancer. Recent studies suggest that neoadjuvant radiation therapy followed by TEM is safe and has results similar to those with abdominal rectal resection for the treatment of extraperitoneal early rectal cancer. Methods and Materials: We planned a prospective pilot study including 25 consecutive patients with extraperitoneal T1-T2 N0 M0 rectal adenocarcinoma undergoing SCRT followed by TEM 4 to 10 weeks later (SCRT-TEM). Safety, efficacy, and acceptability of this treatment modality were compared with historical groups of patients with similar rectal cancer stage and treated with long-course radiation therapy (LCRT) followed by TEM (LCRT-TEM), TEM alone, or laparoscopic rectal resection with total mesorectal excision (TME) at our institution. Results: The study was interrupted after 14 patients underwent SCRT of 25 Gy in 5 fractions followed by TEM. Median time between SCRT and TEM was 7 weeks (range: 4-10 weeks). Although no preoperative complications occurred, rectal suture dehiscence was observed in 7 patients (50%) at 4 weeks follow-up, associated with an enterocutaneous fistula in the sacral area in 2 cases. One patient required a colostomy. Quality of life at 1-month follow-up, according to European Organization for Research and Treatment of Cancer QLQ-C30 survey score, was significantly worse in SCRT-TEM patients than in LCRT-TEM patients (P=.0277) or TEM patients (P=.0004), whereas no differences were observed with TME patients (P=.604). At a median follow-up of 10 months (range: 6-26 months), we observed 1 (7%) local recurrence at 6 months that was treated with abdominoperineal resection. Conclusions: SCRT followed by TEM for T1-T2 N0 rectal cancer is burdened by a high rate of painful dehiscence of the suture line and enterocutaneous

  12. Results of Neoadjuvant Short-Course Radiation Therapy Followed by Transanal Endoscopic Microsurgery for T1-T2 N0 Extraperitoneal Rectal Cancer

    Arezzo, Alberto, E-mail: alberto.arezzo@unito.it [General Surgery I, Department of Surgical Sciences, University of Torino, Torino (Italy); Arolfo, Simone; Allaix, Marco Ettore [General Surgery I, Department of Surgical Sciences, University of Torino, Torino (Italy); Munoz, Fernando [Radiation Oncology, Department of Oncology, University of Torino, Torino (Italy); Cassoni, Paola [Pathology Unit, Department of Medical Sciences, University of Torino, Torino (Italy); Monagheddu, Chiara [Clinical Epidemiology Unit, Piedmont Reference Centre for Epidemiology and Cancer Prevention, City of Health and Science Hospital of Torino, Torino (Italy); Ricardi, Umberto [Radiation Oncology, Department of Oncology, University of Torino, Torino (Italy); Ciccone, Giovannino [Clinical Epidemiology Unit, Piedmont Reference Centre for Epidemiology and Cancer Prevention, City of Health and Science Hospital of Torino, Torino (Italy); Morino, Mario [General Surgery I, Department of Surgical Sciences, University of Torino, Torino (Italy)

    2015-06-01

    Purpose: This study was undertaken to assess the short-term outcomes of neoadjuvant short-course radiation therapy (SCRT) followed by transanal endoscopic microsurgery (TEM) for T1-T2 N0 extraperitoneal rectal cancer. Recent studies suggest that neoadjuvant radiation therapy followed by TEM is safe and has results similar to those with abdominal rectal resection for the treatment of extraperitoneal early rectal cancer. Methods and Materials: We planned a prospective pilot study including 25 consecutive patients with extraperitoneal T1-T2 N0 M0 rectal adenocarcinoma undergoing SCRT followed by TEM 4 to 10 weeks later (SCRT-TEM). Safety, efficacy, and acceptability of this treatment modality were compared with historical groups of patients with similar rectal cancer stage and treated with long-course radiation therapy (LCRT) followed by TEM (LCRT-TEM), TEM alone, or laparoscopic rectal resection with total mesorectal excision (TME) at our institution. Results: The study was interrupted after 14 patients underwent SCRT of 25 Gy in 5 fractions followed by TEM. Median time between SCRT and TEM was 7 weeks (range: 4-10 weeks). Although no preoperative complications occurred, rectal suture dehiscence was observed in 7 patients (50%) at 4 weeks follow-up, associated with an enterocutaneous fistula in the sacral area in 2 cases. One patient required a colostomy. Quality of life at 1-month follow-up, according to European Organization for Research and Treatment of Cancer QLQ-C30 survey score, was significantly worse in SCRT-TEM patients than in LCRT-TEM patients (P=.0277) or TEM patients (P=.0004), whereas no differences were observed with TME patients (P=.604). At a median follow-up of 10 months (range: 6-26 months), we observed 1 (7%) local recurrence at 6 months that was treated with abdominoperineal resection. Conclusions: SCRT followed by TEM for T1-T2 N0 rectal cancer is burdened by a high rate of painful dehiscence of the suture line and enterocutaneous

  13. European Security

    Møller, Bjørn

    Theoretical chapters on "Security", "Organisations" and "Regions," Historical Chapters on "Europe and Its Distinguishing Features" and on "The United Nations," "NATO," "The CSCE/OSCE and the Council of Europe" and "The European Union"...

  14. European Community.

    1987-05-01

    The European Community was established in 1951 to reconcile France and Germany after World War II and to make possible the eventual federation of Europe. By 1986, there were 12 member countries: France, Italy, Belgium, the Federal Republic of Germany, Luxembourg, the Netherlands, Denmark, Ireland, the United Kingdom, Greece, Spain, and Portugal. Principal areas of concern are internal and external trade, agriculture, monetary coordination, fisheries, common industrial and commercial policies, assistance, science and research, and common social and regional policies. The European Community has a budget of US$34.035 billion/year, funded by customs duties and 1.4% of each member's value-added tax. The treaties establishing the European Community call for members to form a common market, a common customs tariff, and common agricultural, transport, economic, and nuclear policies. Major European Community institutions include the Commission, Council of Ministers, European Parliament, Court of Justice, and Economic and Social Committee. The Community is the world's largest trading unit, accounting for 15% of world trade. The 2 main goals of the Community's industrial policy are to create an open internal market and to promote technological innovation in order to improve international competitiveness. The European Community aims to contribute to the economic and social development of Third World countries as well. PMID:12177941

  15. The comparison of salivary level of estrogen and progesterone in 1 st , 2 nd and 3 rd trimester in pregnant women with and without geographic tongue

    Parichehr Ghalayani

    2013-01-01

    Full Text Available Background: Geographic tongue (GT was first reported as a wandering rash of the tongue in 1831; however, its etiopathogenesis remains unclear. Increased prevalence of GT has been documented in the pregnancy. The aim of this study was to compare the level of salivary estrogen and progesterone in pregnant women with and without GT. Materials and Methods: This analytical-descriptive study consisted of 26 pregnant women (13 with GT, 13 without GT with an age range between 18 years and 45 years. The estrogen and progesterone level was measured during 1 st , 2 nd and 3 rd trimester of pregnancy. Saliva sampling was performed to determine the level of sex hormones. The samples were stored at -80°C and determined by Eliza method. The results were analyzed by t-test and repeated measure ANOVA (α = 0.05. Results: The mean level of estrogen for control and case group was 49.4and 52.33 in the 1 st , 71.05 and 74.12 in the 2 nd and 109.1 and 112.16 in the 3 rd trimester respectively. The mean level of progesterone was 0.72 and 0.72 in the 1 st , 1.14 and 1.21 in the 2 nd and 1.3 and 1.28 in the 3 rd trimester of pregnancy for the control and case groups respectively. Even though, there was no significant difference regarding the level of sex hormones between case and control groups (P > 0.05, but the difference between the level of these hormones during 3 trimesters of pregnancy was significant in each group (P = 0.001. Conclusion: The level of sex hormones is not the only etiologic factor of GT in pregnant women, but other factors such as genetic potential, human leukocyte antigen marker and stress may aggravate the incidence of this lesion.

  16. Characterization of the 1st and 2nd EF-hands of NADPH oxidase 5 by fluorescence, isothermal titration calorimetry, and circular dichroism

    Wei Chin-Chuan

    2012-04-01

    Full Text Available Abstract Background Superoxide generated by non-phagocytic NADPH oxidases (NOXs is of growing importance for physiology and pathobiology. The calcium binding domain (CaBD of NOX5 contains four EF-hands, each binding one calcium ion. To better understand the metal binding properties of the 1st and 2nd EF-hands, we characterized the N-terminal half of CaBD (NCaBD and its calcium-binding knockout mutants. Results The isothermal titration calorimetry measurement for NCaBD reveals that the calcium binding of two EF-hands are loosely associated with each other and can be treated as independent binding events. However, the Ca2+ binding studies on NCaBD(E31Q and NCaBD(E63Q showed their binding constants to be 6.5 × 105 and 5.0 × 102 M-1 with ΔHs of -14 and -4 kJ/mol, respectively, suggesting that intrinsic calcium binding for the 1st non-canonical EF-hand is largely enhanced by the binding of Ca2+ to the 2nd canonical EF-hand. The fluorescence quenching and CD spectra support a conformational change upon Ca2+ binding, which changes Trp residues toward a more non-polar and exposed environment and also increases its α-helix secondary structure content. All measurements exclude Mg2+-binding in NCaBD. Conclusions We demonstrated that the 1st non-canonical EF-hand of NOX5 has very weak Ca2+ binding affinity compared with the 2nd canonical EF-hand. Both EF-hands interact with each other in a cooperative manner to enhance their Ca2+ binding affinity. Our characterization reveals that the two EF-hands in the N-terminal NOX5 are Ca2+ specific. Graphical abstract

  17. Characterization of low and medium-level radioactive waste forms. Final report - 2nd Programme 1980-84

    The European Communities Second R and D Programme 1980-84 'Management and Disposal of Radioactive Waste (Shared cost action)' included a closely coordinated research activity for the 'Characterization of low and medium-level radioactive waste forms'. This report summarizes the main results obtained during the five years of the programme by laboratories in seven European countries participating in the coordinated RandD efforts. Ten reference waste forms have been selected, based on the most important types of low and medium-level waste arisings and the three commonly used immobilization matrices: cement, bitumen and polymers. The investigated properties were mainly: waste-matrix compatibility, radiation effects, leaching behaviour, leached radionuclides speciation, microbiological resistance and thermal as well as mechanical properties. Extensive experimental results relevant for the qualification of waste products and for application in performance analysis are presented in this final report. The main conclusions are drawn for the confinement properties of these different waste forms. These conclusions have also shown the necessity of selecting several other reference waste forms for the continuation of this RandD action now being launched in the Third EC Programme 1985-89

  18. Intersphincteric Resection for Low Rectal Cancer – Case Report

    Russu Cristian

    2016-03-01

    Full Text Available Introduction: Surgical treatment for low rectal cancer represents a challenge: to perform a radical resection and to preserve the sphincter’s function. We report a case of intersphincteric resection in a combined multimodality treatment for low rectal cancer, with good oncologic and functional outcome. Case presentation: We report a case of a 73 years old woman admitted in April 2014 in surgery, for low rectal cancer. The diagnostic was established by colonoscopy and malignancy confirmed by biopsy. Complete imaging was done using computed tomography and magnetic resonance to establish the exact stage of the disease. The interdisciplinary individualized treatment began with radiotherapy (total dose of 50 Gy, administered in 25 fractions followed by surgery after eight weeks. We performed intersphincteric rectal resection by a modified Schiessel technique. There were no postoperative complications and the oncologic and functional results were very good at one year follow up. Conclusions: Intersphincteric resection, in this selected case of low rectal cancer, represented an efficient surgical treatment, with good functional results and quality of life for the patient. A multidisciplinary team is an invaluable means of assessing and further managing the appropriate, tailored to the case, treatment in the aim of achieving best results.

  19. Patterns of metastasis in colon and rectal cancer.

    Riihimäki, Matias; Hemminki, Akseli; Sundquist, Jan; Hemminki, Kari

    2016-01-01

    Investigating epidemiology of metastatic colon and rectal cancer is challenging, because cancer registries seldom record metastatic sites. We used a population based approach to assess metastatic spread in colon and rectal cancers. 49,096 patients with colorectal cancer were identified from the nationwide Swedish Cancer Registry. Metastatic sites were identified from the National Patient Register and Cause of Death Register. Rectal cancer more frequently metastasized into thoracic organs (OR = 2.4) and the nervous system (1.5) and less frequently within the peritoneum (0.3). Mucinous and signet ring adenocarcinomas more frequently metastasized within the peritoneum compared with generic adenocarcinoma (3.8 [colon]/3.2 [rectum]), and less frequently into the liver (0.5/0.6). Lung metastases occurred frequently together with nervous system metastases, whereas peritoneal metastases were often listed with ovarian and pleural metastases. Thoracic metastases are almost as common as liver metastases in rectal cancer patients with a low stage at diagnosis. In colorectal cancer patients with solitary metastases the survival differed between 5 and 19 months depending on T or N stage. Metastatic patterns differ notably between colon and rectal cancers. This knowledge should help clinicians to identify patients in need for extra surveillance and gives insight to further studies on the mechanisms of metastasis. PMID:27416752

  20. Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma

    Miller, Cassandra L.; Muthupalani, Sureshkumar; Shen, Zeli; Drees, Frauke; Ge, Zhongming; Feng, Yan; Chen, Xiaowei; Gong, Guanyu; Nagar, Karan K.; Wang, Timothy C.; Gertler, Frank B.; Fox, James G.

    2016-01-01

    During a survey of clinical rectal prolapse (RP) cases in the mouse population at MIT animal research facilities, a high incidence of RP in the lamellipodin knock-out strain, C57BL/6-Raph1tm1Fbg (Lpd-/-) was documented. Upon further investigation, the Lpd-/- colony was found to be infected with multiple endemic enterohepatic Helicobacter species (EHS). Lpd-/- mice, a transgenic mouse strain produced at MIT, have not previously shown a distinct immune phenotype and are not highly susceptible to other opportunistic infections. Predominantly male Lpd-/- mice with RP exhibited lesions consistent with invasive rectal carcinoma concomitant to clinically evident RP. Multiple inflammatory cytokines, CD11b+Gr1+ myeloid-derived suppressor cell (MDSC) populations, and epithelial cells positive for a DNA damage biomarker, H2AX, were elevated in affected tissue, supporting their role in the neoplastic process. An evaluation of Lpd-/- mice with RP compared to EHS-infected, but clinically normal (CN) Lpd-/- animals indicated that all of these mice exhibit some degree of lower bowel inflammation; however, mice with prolapses had significantly higher degree of focal lesions at the colo-rectal junction. When Helicobacter spp. infections were eliminated in Lpd-/- mice by embryo transfer rederivation, the disease phenotype was abrogated, implicating EHS as a contributing factor in the development of rectal carcinoma. Here we describe lesions in Lpd-/- male mice consistent with a focal inflammation-induced neoplastic transformation and propose this strain as a mouse model of rectal carcinoma. PMID:27045955

  1. Sexual Function in Males After Radiotherapy for Rectal Cancer

    Purpose: Knowledge of sexual problems after pre- or postoperative radiotherapy (RT) with 50 Gy for rectal cancer is limited. In this study, we aimed to compare self-rated sexual functioning in irradiated (RT+) and nonirradiated (RT-) male patients at least 2 years after surgery for rectal cancer. Methods and Materials: Patients diagnosed with rectal cancer from 1993 to 2003 were identified from the Norwegian Rectal Cancer Registry. Male patients without recurrence at the time of the study. The International Index of Erectile Function, a self-rated instrument, was used to assess sexual functioning, and serum levels of serum testosterone were measured. Results: Questionnaires were returned from 241 patients a median of 4.5 years after surgery. The median age was 67 years at survey. RT+ patients (n = 108) had significantly poorer scores for erectile function, orgasmic function, intercourse satisfaction, and overall satisfaction with sex life compared with RT- patients (n = 133). In multiple age-adjusted analysis, the odds ratio for moderate-severe erectile dysfunction in RT+ patients was 7.3 compared with RT- patients (p <0.001). Furthermore, erectile dysfunction of this degree was associated with low serum testosterone (p = 0.01). Conclusion: RT for rectal cancer is associated with significant long-term effects on sexual function in males.

  2. Bladder and rectal complications following radiotherapy for cervix cancer

    One-hundred and thirty-two patients with cervix carcinoma who were treated with whole pelvis irradiation and two intracavitary applications had bladder and rectal dosimetry during brachytherapy with contrast agents placed into the bladder and rectum prior to orthogonal simulator radiographs. Doses were computer calculated at points A and B, F (bladder), R1 (rectum), and R2 (rectosigmoid). Late occurring bladder and rectal complications were graded on a severity scale of 1 to 3, and 14% had grade 2 or 3 injuries (9% developed fistulas). Statistical evaluation of the data showed that severe bladder and rectal injuries occur more commonly in stage IIIA and IIIB disease and in those receiving high external beam doses (5000 rad +). Analysis of variance tests revealed a significant correlation of brachytherapy dose to points R1 and R2 with severe rectal injuries but there was not a correlation of dose to F with bladder injuries. Nor was there correlation of injuries with dose to point A or the milligram-hour dose. We conclude that our technique for rectal dosimetry is adequate but that an improved technique of bladder dosimetry is needed. Also, when combining whole pelvis irradiation with two intracavitary applications (4000 rad to point A), the whole pelvis dose should probably not exceed 4000-4500 rad

  3. Toward Restored Bowel Health in Rectal Cancer Survivors.

    Steineck, Gunnar; Schmidt, Heike; Alevronta, Eleftheria; Sjöberg, Fei; Bull, Cecilia Magdalena; Vordermark, Dirk

    2016-07-01

    As technology gets better and better, and as clinical research provides more and more knowledge, we can extend our ambition to cure patients from cancer with restored physical health among the survivors. This increased ambition requires attention to grade 1 toxicity that decreases quality of life. It forces us to document the details of grade 1 toxicity and improve our understanding of the mechanisms. Long-term toxicity scores, or adverse events as documented during clinical trials, may be regarded as symptoms or signs of underlying survivorship diseases. However, we lack a survivorship nosology for rectal cancer survivors. Primarily focusing on radiation-induced side effects, we highlight some important observations concerning late toxicity among rectal cancer survivors. With that and other data, we searched for a preliminary survivorship-disease nosology for rectal cancer survivors. We disentangled the following survivorship diseases among rectal cancer survivors: low anterior resection syndrome, radiation-induced anal sphincter dysfunction, gut wall inflammation and fibrosis, blood discharge, excessive gas discharge, excessive mucus discharge, constipation, bacterial overgrowth, and aberrant anatomical structures. The suggested survivorship nosology may form the basis for new instruments capturing long-term symptoms (patient-reported outcomes) and professional-reported signs. For some of the diseases, we can search for animal models. As an end result, the suggested survivorship nosology may accelerate our understanding on how to prevent, ameliorate, or eliminate manifestations of treatment-induced diseases among rectal cancer survivors. PMID:27238476

  4. Changing practice of rectal cancer surgery in Pakistan

    Objective: To describe the presentation and pathology of rectal cancer, and to evaluate the local experience after total meso rectal excision at a tertiary care hospital in Pakistan. Methodology: A retrospective study of two hundred cases of carcinoma rectum that had undergone total meso rectal excision at Liaquat University Hospital Jamshoro Pakistan was carried out from January 1998 to December 2007.The cases were admitted through outpatient and emergency departments. The demographic details of each patient and variables such as clinical presentation, tumor location, Dukes staging, TNM staging, operations and complications were recorded on proformas. Each patient was followed up at two months for one year, every four months for three years and annually thereafter. Results: Male to female ratio being almost equal 1.6:1, Age ranged from 14-70 years. Site of tumor at upper one third 25%, middle one third 30% and lower one third 45%. Majority of patients (more than 62%) were in Dukes B Group.There were no postoperative deaths, complications occurred in a total of 59 (29.5%) patients, which were mostly colostomy related (13.0%). The abdominal wound infection 5%, anastomotic dehiscence 1.0%, urinary tract infection 5%, and impotence occurred in 1.5%. In 20% patients local recurrence was detected. Conclusion: Total meso rectal excision is a safe and feasible technique for rectal cancer surgery with acceptable perioperative morbidity and adequate local disease control. (author)

  5. Experimental Investigation of 2nd Generation Bioethanol Derived from Empty-fruit-bunch (EFB) of Oil-palm on Performance and Exhaust Emission of SI Engine

    Yanuandri Putrasari; Haznan Abimanyu; Achmad Praptijanto; Arifin Nur; Yan Irawan; Sabar Pangihutan Simanungkalit

    2014-01-01

    The experimental investigation of 2nd generation bioethanol derived from EFB of oil-palm blended with gasoline for 10, 20, 25% by volume and pure gasoline were conducted on performance and exhaust emission tests of SI engine. A four stroke, four cylinders, programmed fuel injection (PGMFI), 16 valves variable valve timing and electronic lift control (VTEC), single overhead camshaft (SOHC), and 1,497 cm3 SI engine (Honda/L15A) was used in this investigation. Engine performance test was carried...

  6. 2nd (final) IAEA research co-ordination meeting on 'plasma-material interaction data for mixed plasma facing materials in fusion reactors'. Summary report

    The proceedings and conclusions of the 2nd Research Co-ordination Meeting on 'Plasma-Material Interaction Data for Mixed Plasma Facing Materials in Fusion Reactors', held on October 16 and 17, 2000 at the IAEA Headquarters in Vienna, are briefly described. This report includes a summary of the presentations made by the meeting participants and a review of the accomplishments of the Co-ordinated Research Project (CRP). In addition, short summaries from the participants are included indicating the specific research completed in support of this CRP. (author)

  7. Proceedings of the 2nd NUCEF international symposium NUCEF'98. Safety research and development of base technology on nuclear fuel cycle

    This volume contains 68 papers presented at the 2nd NUCEF International Symposium NUCEF'98 held on 16-17 November 1998, in Hitachinaka, Japan, following the 1st symposium NUCEF'95 (Proceeding: JAERI-Conf 96-003). The theme of this symposium was 'Safety Research and Development of Base Technology on Nuclear Fuel Cycle'. The papers were presented in oral and poster sessions on following research fields: (1) Criticality Safety, (2) Reprocessing and Partitioning, (3) Radioactive Waste Management. The 68 papers are indexed individually. (J.P.N.)

  8. Developments in vision care optics and clinical optometry: [abstracts’ book of the] 2nd International Summer School on Advances in Ophthalmic Optics and Optometry (OOPT’2013)

    Manuel F. M. Costa; Baptista, António M. G., ed. lit.; International Summer School Recent Advances in Ophthalmic Optics and Optometry, 2, Braga, 2013; OOPT’2012

    2013-01-01

    2nd International Summer School on Advances in Ophthalmic Optics and Optometry”. Na sequência da primeira edição da OOPT quedecorreu em Aveiro, em Setembro do ano transacto, com elevado sucesso, este evento é o reflexo do extraordinário desenvolvimento recente que a Optometria tem tido no nosso país (sendo de destacar a calendarização do projecto lei que visa a regulamentação da Optometria) e que resulta da profícua colaboração entre a Associação de Profissionais Licenciados de Opto...

  9. 2nd IAEA research coordination meeting on collection and evaluation of reference data for thermo-mechanical properties of fusion reactor plasma facing materials. Summary report

    The proceedings and results of the 2nd IAEA Research Coordination Meeting on ''Collection and Evaluation of Reference Data for Thermo-mechanical Properties of Fusion Reactor Plasma Facing Materials'' held on March 25, 26 and 27, 1996 at the IAEA Headquarters in Vienna are briefly described. This report includes a summary of presentations made by the meeting participants, the results of discussions amongst the participants regarding the status of data, publication of a multi-author review paper and recommendations regarding future work. (author). 1 tab

  10. 2nd (final) IAEA research co-ordination meeting on 'charge exchange cross section data for fusion plasma studies'. Summary report

    The proceedings and conclusions of the 2nd Research Co-ordination Meeting on 'Charge Exchange Cross Section Data for Fusion Plasma Studies', held on September 25 and 26, 2000 at the IAEA Headquarters in Vienna, are briefly described. This report includes a summary of the presentations made by the meeting participants and a review of the accomplishments of the Co-ordinated Research Project (CRP). In addition, short summaries from the participants are included indicating the specific research completed in support of this CRP. (author)

  11. Proceedings of the 2nd NUCEF international symposium NUCEF`98. Safety research and development of base technology on nuclear fuel cycle

    NONE

    1999-03-01

    This volume contains 68 papers presented at the 2nd NUCEF International Symposium NUCEF`98 held on 16-17 November 1998, in Hitachinaka, Japan, following the 1st symposium NUCEF`95 (Proceeding: JAERI-Conf 96-003). The theme of this symposium was `Safety Research and Development of Base Technology on Nuclear Fuel Cycle`. The papers were presented in oral and poster sessions on following research fields: (1) Criticality Safety, (2) Reprocessing and Partitioning, (3) Radioactive Waste Management. The 68 papers are indexed individually. (J.P.N.)

  12. Sr2(Nd, Ce)2MCu2O9, M=Al, Co, Ga. A new layered copper oxide structure type

    A new layered copper oxide structure type is reported based on the ordered interleaving of AlO4, CoO4 or GaO4 tetrahedra between the apices of copper oxides pyramids, and an (Nd, Ce)2O2 fluorite layer between the bases of the pyramids. Despite the structural similarities to the recently reported Sr2(Y,Ca)GaCu2O7 and Sr2(Nd,Ce)2NbCu2O10 superconducting structure types, we have not been able to find conditions which produce superconductivity in the present materials. (orig.)

  13. [Influence of hypocaloric diet with addition of a vitamin-mineral complex on status of patients with obesity 1st and 2nd degrees].

    Sharafetdinov, Kh Kh; Plotnikova, O A; Zykina, V V; Mal'tsev, G Iu; Sokol'nikov, A A; Kaganov, B S

    2011-01-01

    Addition of a vitamin-mineral complex (VMC) to a standard hypocaloric diet leads to a positive dynamics of antropometric characteristics in patients with obesity 1st and 2nd degrees which is comparable to effectiveness of standard dietotherapy (dietary treatment) traditionally used in complex treatment of obesity. Addition of 1,8 mg of vitamin B2 as part of VMC to a hypocaloric diet is shown to be inadequate in eradication of marginal provision of riboflavin when using diets reduced in calories. PMID:22232885

  14. Quantitative analysis of methylation of genomic loci in early-stage rectal cancer predicts distant recurrence.

    Maat, M.F. de; Velde, C.J. van de; Werff, M.P. van der; Putter, H.; Umetani, N.; Klein-Kranenbarg, E.M.; Turner, R.R.; Krieken, J.H.J.M. van; Bilchik, A.; Tollenaar, R.A.; Hoon, D.S.

    2008-01-01

    PURPOSE: There are no accurate prognostic biomarkers specific for rectal cancer. Epigenetic aberrations, in the form of DNA methylation, accumulate early during rectal tumor formation. In a preliminary study, we investigated absolute quantitative methylation changes associated with tumor progression

  15. Improved quality of care for patients undergoing an abdominoperineal excision for rectal cancer

    Bokkerink, G.M.J.; Buijs, E.F.; Ruijter, W. de; Rosman, C.; Sietses, C.; Strobel, R.; Heisterkamp, J.; Nagtegaal, I.D.; Bremers, A.J.A.; Wilt, J.H.W. de

    2015-01-01

    INTRODUCTION: New diagnostics, the emergence of total mesorectal excision and neoadjuvant treatments have improved outcome for patients with rectal cancer. Patients with distal rectal cancer undergoing an abdominoperineal excision seem to do worse compared to those treated with sphinctersparing tech

  16. Indication for radiotherapy in rectal carcinoma

    Surgery and radiotherapy complete each other in local control of suffering from rectal carcinoma. A radiotherapeutic effect on tumor is secured often. The adjuvant radiotherapy is the most interesting indication, though the most controversial as present too. Analysing all data and with experiences of an own irradiation study we have not any doubt that the indication is qualified for a combined therapy, if the therapeutic aim with priority is to prevent a local relapse as the most frequent and complaintful form of therapeutic failure. In this problem, radical irradiation forms, as pre- and accumulating irradiation (sandwich-technique) and after-irradiation, render superior to an exclusive preirradiation. In result of this tudy we practise a preirradiation of 25 Gy with immediately following operation and an accumulating irradiation to 50 Gy in proved high-risk-stage (T≥3N0M0.TxN1-3M0). If there is a primary local incurability by tumor invasion into the neighbourhood a pre-irradiation is done with 50Gy and following explorative laparatomy within 4-6 weeks. Nearly 60% of these tumors become operably after thast. Likewise we practise in unirradiated patients with locoregional tumor recurrence. Also here the exstirpation quote of recurred tumor can be doubled approximately. The 5-years-survival is 20-30% in both indication groups. In patients with general or systematic incurability, that a stoma construction is required in, we carry out a transanal tumor reduction and irradiate with 50Gy after that. Especially this therapeutic principle has proved its worth in patients that are past eighty. Here with acceptable living quality and avoiding a stoma construction a survival can be reached that corresponds to the statistical survival of this stage of life. (orig.)

  17. [Current MRI staging of rectal cancer].

    Wietek, B M; Kratt, T

    2012-11-01

    Colorectal carcinoma is the second most prevalent cause for cancer, and has very variable outcomes. Advancements in surgery, the change from adjuvant to neo-adjuvant radio-chemo-therapies as well as in clinical diagnostics have improved the prognosis for patients in a multi-modal therapy concept. An accurate primary staging including a reliable prediction of the circumferential resection margin (CRM) has established MR Imaging (MRI) beside intraluminal endoscopic ultrasound (EUS). MRI facilitates the selection of patients likely to benefit from a preoperative therapy, especially in cases of unfavorable factors. Currently the relationship of the tumor to the mesorectal fascia has become a more important prognostic factor than the T-staging, particularly for surgical therapy. In addition further prognostic factors like the depth of infiltration into the perirectal fat and the extramural venous infiltration (EMVI) have important impact on therapy and prognosis. High resolution MRI has proved useful in clarifying the relationship between the tumor and the mesorectal fascia, which represents the CRM at the total mesorectal excision (TME) especially in the upper and middle third. Preoperative evaluation of the other prognostic factors as well as the nodal status is still difficult. It is used increasingly not only for primary staging but also progressively for the monitoring of neoadjuvant therapy. The addition of diffusion weighted imaging (DWI) is an interesting option for the improvement of response evaluation. The following overview provides an introduction of MRI diagnosis as well as its importance for the evaluation of the clinically relevant prognostic factors leading to an improvement of therapy and prognosis of patients with rectal carcinoma. PMID:22893486

  18. Risk factors of circumferential resection margin involvement in the patients with extraperitoneal rectal cancer

    Oh, Sung Jin; Shin, Jin Yong

    2012-01-01

    Purpose Currently, circumferential resection margins (CRM) are used as a clinical endpoint in studies on the prognosis of rectal cancer. Although the concept of a circumferential resection margin in extraperitoneal rectal cancer differs from that in intraperitoneal rectal cancer due to differences in anatomical and biologic behaviors, previous reports have provided information on CRM involvement in all types of rectal cancer including intraperitoneal lesions. Therefore, the aim of this study ...

  19. Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention

    Sheng-Xiang Rao; Meng-Su Zeng; Jian-Ming Xu; Xin-Yu Qin; Cai-Zhong Chen; Ren-Chen Li; Ying-Yong Hou

    2007-01-01

    AIM: To determine the accuracy of high-resolution magnetic resonance imaging (MRI) using phased-array coil for preoperative assessment of T staging and mesorectal fascia infiltration in rectal cancer with rectal distention.METHODS: In a prospective study of 67 patients with primary rectal cancer, high-resolution magnetic resonance imaging (in-plane resolution, 0.66 × 0.56)with phased-array coil were performed for T-staging and measurement of distance between the tumor and the mesorectal fascia. The assessment of MRI was compared with postoperative histopathologic findings. Sensitivity,specificity, accuracy, positive predictive value, and negative predictive value were evaluated.RESULTS: The overall magnetic resonance accuracy was 85.1% for T staging and 88% for predicting mesorectal fascia involvement. Magnetic resonance sensitivity, specificity, accuracy, positive predictive value,and negative predictive value was 70%, 97.9%, 89.6%,93.3% and 88.5% for ≤ T2 tumors, 90.5%, 76%,85.1%, 86.4% and 82.6% for T3 tumors, 100%, 95.2%,95.5%, 62.5% and 100% for T4 tumors, and 80%,90.4%, 88%, 70.6% and 94% for predicting mesorectal fascia involvement, respectively.CONCLUSION: High-resolution MRI enables accurate preoperative assessment for T staging and mesorectal fascia infiltration in rectal cancer with rectal distention.

  20. European visit

    2006-01-01

    The European Commissioner for Science and Research, Janez Potočnik, (on the right) visited the CMS assembly hall accompanied by Jim Virdee, Deputy Spokesman of CMS (on the left), and Robert Aymar, Director-General of CERN. The European Commissioner for Science and Research, Janez Potočnik, visited CERN on Tuesday 31 January. He was welcomed by the Director-General, Robert Aymar, who described the missions and current activities of CERN to him, in particular the realisation of the LHC with its three components: accelerator, detectors, storage and processing of data. The European Commissioner then visited the CMS assembly hall, then the hall for testing the LHC magnets and the ATLAS cavern. During this first visit since his appointment at the end of 2004, Janez Potočnik appeared very interested by the operation of CERN, an example of successful scientific co-operation on a European scale. The many projects (30 on average) that CERN and the European Commission carry out jointly for the benefit of res...

  1. Comparison between two perineal procedures for treatment of rectal prolaps

    Ahmed Mohamed Abozid, Nabila Mohamed A. Shams, , Yahia Hassan

    2001-09-01

    Full Text Available The optimal surgical procedures for the management of rectal prolapse is still under debate so comparison between two operations were done in our series. Eighteen patients with complete rectal prolaps were treated surgically through the perineum they were divided into two groups. First group were treated by recto-segmoidectomy and levatroplasty to fortify the pelvic floor, the second group were treated by rectopexy using prolene mesh and levetroplasty to fortify the pelvic floor, the mesh was inserted between the rectum and sacrum and fixed through perineal incision. The recurrence rate !""#$$!%$ &significant difference in hospital stay among both groups. Also there were no other cases of postoperative complications such as anastomotic leak or stricture, affection of the bladder dysfunction in both groups. Aim of work The aim of this work was to compare the short-term outcome of two different perineal operative procedures in patients with full thickness rectal prolaps.

  2. Rectal cancer: Possibilities of MRI in detection of local recurrence

    Miučin-Vukadinović Ivana

    2008-01-01

    Full Text Available Introduction Treatment of rectal cancer, which includes periodic evaluations, may lead to earlier identification of recurrent local infiltration. Differentiation between local recurrence and other post radiation changes is frequently rather difficult. Pelvic MR examination was performed in 30 patients (20 men, 10 women at the Institute of oncology, Sremska Kamenica. All patients underwent surgical resection of rectal cancer at the same institution. Preoperative or postoperative radiation therapy was administrated in 29 patients (93%. Criteria for detection of local recurrent tumors were based on morphologic changes, such as the presence of tumor infiltration, size increase of the mass and the change of the mass shape. Recurrent tumor infiltration was detected in 50% patents. Tumors of low differentiation histological type was predominantly found within 10 months after surgery, while moderately differentiated and high differentiated types were detected within 20 months and after 20 months after resection, respectively. Pelvic MR examination represents important diagnostic modality for recurrent rectal cancer identification.

  3. Treatment of advanced rectal cancer after renal transplantation

    Hai-Yi Liu; Xiao-Bo Liang; Yao-Ping Li; Yi Feng; Dong-Bo Liu; Wen-Da Wang

    2011-01-01

    Renal transplantation is a standard procedure for end-stage renal disease today. Due to immunosuppressive drugs and increasing survival time after renal trans-plantation, patients with transplanted kidneys carry an increased risk of developing malignant tumors. In this case report, 3 patients with advanced rectal can-cer after renal transplantation for renal failure were treated with anterior resection or abdominoperineal resection plus total mesorectal excision, followed by adjuvant chemotherapy. One patient eventually died of metastasized cancer 31 mo after therapy, although his organ grafts functioned well until his death. The other 2 patients were well during the 8 and 21 mo follow-up periods after rectal resection. We therefore strongly argue that patients with advanced rectal cancer should receive standard oncology treatment, including opera-tion and adjuvant treatment after renal transplantation. Colorectal cancer screening in such patients appears justified.

  4. Rectal cancer in pregnancy: A diagnostic and therapeutic challenge

    Introduction: The occurrence of colorectal cancer during pregnancy is rare and is associated with diagnostic and therapeutic challenges. Herein, we report such a case of rectal cancer in pregnancy and review the literature. Case report: A 31-year-old multiparous, pregnant woman, in the 20th week of gestation, presented with rectal bleeding progressing to spasmodic abdominal pain and right flank vague pain. A flexible recto sigmoidoscopy showed a large ulcerative mass located in the recto sigmoid junction, 15 cm away from anal verge. Imaging studies and biopsy proved it to be rectal adenocarcinoma with single liver metastasis. The patient’s pregnancy was terminated and neoadjuvant therapy followed by curative surgery was performed. She is currently receiving adjuvant systemic therapy to eradicate potential micro metastatic disease. Conclusion: This case suggests that colorectal cancer can mimic the signs and the symptoms of pregnancy and tends to present at an advanced stage in pregnant women.

  5. Ultrasound tomography in the diagnosis of rectal carcinoma relapses

    The results of ultrasonography in 616 patients after radical surgery of rectal carcinomas are committed. In the first group, patients with clinical symptoms of a relapse, the method detected tumors in 146 (80.2%) of 182 patients. The error rate was 12.1. In the second group, patients with unfavourable postoperative prognosis, ultrasound follow-up detected relapses previous to their clinical manifestation in 73 (16.8%) of 434 patients. The method turned out to be effective even for the detection of small (less than 3 cm) recurrences after rectal exstirpation. For intraintestinal recurrences after rectal resection ultrasonography can determine the degree of infiltration outside the organ. Real-time scans can prevent some of the errors that occur with compound scans. (author)

  6. [Robot-assisted rectal surgery: hype or progress?].

    Becker, T; Egberts, J E; Schafmayer, C; Aselmann, H

    2016-07-01

    Minimally invasive laparoscopic surgery for rectal cancer has undergone a significant evolution during the last decades and has become the standard approach in specialized centers with better short-term and comparable oncological outcome to open surgery. The laparoscopic approach remains challenging and has various inherent technical challenges particularly associated with rectal cancer resection. Robotic colorectal surgery using the da Vinci® surgical system has been successfully introduced into clinical practice during recent years and provides specific technical advantages. Studies have shown that the robotic approach in colorectal surgery is safe and feasible with comparable results. It is associated with low conversion rates, more R0 situations for low rectal cancer with larger tumors and more neoadjuvant treatment compared to standard laparoscopy. Robot-assisted surgery is an attractive development of minimally invasive surgery and should also be further evaluated with mandatory monitoring of outcome parameters in registries in Germany. PMID:27334630

  7. Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer

    Background and purpose: Preoperative radiotherapy for rectal cancer has a detrimental effect on long-term anorectal function and quality of life, additional to that observed after rectal resection. The exact physiological mechanisms for the excess impairment remain unknown. We aimed to investigate neorectal and anal sphincter properties in patients treated with neoadjuvant therapy (NT) prior to total mesorectal excision (TME). Material and methods: Sixteen patients (NT+ patients) were examined by multimodal neorectal stimulation and standard anorectal physiological testing. Data were compared to the results of 23 patients, who underwent TME without NT (NT− patients). Results: NT+ patients had elevated sensory thresholds to heat (median temperature, 60 vs. 55 °C; p 2O; p = 0.05). Conclusions: Pelvic radiotherapy causes neorectal hyposensitivity to mechanical and thermal stimuli in patients receiving NT prior to TME surgery for rectal cancer, possibly due to impaired afferent nerve function

  8. Rare case of huge rectal and uterovaginal prolapse

    Manisha M. Laddad

    2013-04-01

    Full Text Available A case of combined genital prolapse and rectal prolapse in a 60-year-old multipara is reported. The treatment of mixed prolapse remains surgical and should be treated the genital prolapse by vaginal hysterectomy with pelvic floor repair and the rectal prolapse by means of the Delorme operation. The mortality and morbidity rates are zero if this operation is used and the relapse rate is only 8 to 11% for the rectal prolapse. It would appear that the two approaches are rarely associated by the authors and would seem to be interesting to reconsider this question by indicating mixed treatment of the two prolapses whenever possible. [Int J Reprod Contracept Obstet Gynecol 2013; 2(2.000: 237-239

  9. Critical appraisal of laparoscopic vs open rectal cancer surgery

    Tan, Winson Jianhong; Chew, Min Hoe; Dharmawan, Angela Renayanti; Singh, Manraj; Acharyya, Sanchalika; Loi, Carol Tien Tau; Tang, Choong Leong

    2016-01-01

    AIM: To evaluate the long-term clinical and oncological outcomes of laparoscopic rectal resection (LRR) and the impact of conversion in patients with rectal cancer. METHODS: An analysis was performed on a prospective database of 633 consecutive patients with rectal cancer who underwent surgical resection. Patients were compared in three groups: Open surgery (OP), laparoscopic surgery, and converted laparoscopic surgery. Short-term outcomes, long-term outcomes, and survival analysis were compared. RESULTS: Among 633 patients studied, 200 patients had successful laparoscopic resections with a conversion rate of 11.1% (25 out of 225). Factors predictive of survival on univariate analysis include the laparoscopic approach (P = 0.016), together with factors such as age, ASA status, stage of disease, tumor grade, presence of perineural invasion and vascular emboli, circumferential resection margin oncologic outcomes when compared to OP. Laparoscopic conversion does not confer a worse prognosis. PMID:27358678

  10. Rectal bleeding after hypofractionated radiotherapy for prostate cancer: Correlation between clinical and dosimetric parameters and the incidence of grade 2 or worse rectal bleeding

    Purpose: To investigate the incidence and severity of rectal bleeding after high-dose hypofractionated radiotherapy (RT) for prostate cancer, and to explore the factors affecting the incidence of Grade 2 or worse rectal bleeding. Methods and materials: The data of 52 patients who had been treated by external beam RT for localized prostate cancer between 1999 and 2002 were analyzed. All the patients had received hypofractionated external beam RT to a total dose of 69 Gy in 3-Gy fractions, three fractions weekly. The clinical and dosimetric factors affecting the incidence of Grade 2 or worse late rectal bleeding were analyzed by univariate and multivariate analyses. The effect of the percentage of the whole rectal volume receiving 30%, 50%, 80%, and 90% of the prescribed radiation dose (V30, V50, V80, and V90, respectively) on the incidence of rectal bleeding was evaluated. Results: Of the 52 patients, 13 (25%) developed Grade 2 or worse rectal bleeding. One patient who needed laser coagulation and blood transfusion for the treatment of rectal bleeding was classified as having Grade 3 rectal bleeding. The median time to the development of Grade 2 or worse rectal bleeding was 11 months. The results of the univariate analysis revealed that the presence of a history of diabetes mellitus (p 30 ≥ 60%, V50 ≥ 40% (p 80 ≥ 25%, and V90 ≥ 15% (p < 0.001) were statistically significant risk factors for the occurrence of Grade 2 or worse rectal bleeding. The results of the multivariate analysis revealed that a history of diabetes mellitus was the most statistically significant risk factor for the occurrence of rectal bleeding after hypofractionated RT for prostate cancer (p < 0.05). Conclusion: A history of diabetes mellitus was the most statistically significant risk factor for the occurrence of Grade 2 or worse rectal bleeding after high-dose hypofractionated RT, although dosimetric factors were also closely associated with the risk of rectal bleeding

  11. Proctitis after external-beam radiotherapy for prostate cancer classified by Vienna Rectoscopy Score and correlated with EORTC/RTOG score for late rectal toxicity: Results of a prospective multicenter study of 166 patients

    Purpose: To evaluate the Vienna Rectoscopy Score (VRS) as a feasible and effective tool for detecting and classifying pathologic changes in the rectal mucosa after radiotherapy (RT) for prostate cancer, and, also, to correlate its findings with the European Organization for Research and Treatment of Cancer (EORTC)/Radiation Therapy Oncology Group (RTOG) score for late rectal toxicity. Methods and Materials: A total of 486 patients with localized prostate cancer underwent external-beam RT up to 70 or 74 Gy within an Austrian-German prospective multicenter trial. In 166 patients, voluntary rectal sigmoidoscopy was performed before and at 12 and/or 24 months after RT. Pathologic findings such as telangiectasia, congested mucosa, and ulcers were graded (Grades 0-3) and summarized according to the VRS. Late rectal side effects (EORTC/RTOG) were documented and correlated with the corresponding VRS. Results: Before RT, 99% had a VRS score of 0. The median follow-up was 40 months. Overall, a late rectal side effects grade or score 1-3 was detected in 43% by EORTC/RTOG compared with 68% by VRS (p < 0.05). Grades 0, 1, 2, and 3 late rectal side effects were found using EORTC/RTOG in 57%, 11%, 28%, and 3%, respectively; the corresponding percentages were 32%, 22%, 32%, and 14% for a VRS of 0, 1, 2, and 3, respectively. A significant coherence between the VRS and EORTC/RTOG was found (p < 0.01). Conclusions: The VRS is a feasible and effective tool for describing and classifying pathologic findings in the rectal mucosa after RT within a multicenter trial. The VRS and EORTC/RTOG showed a high coherence. However the VRS was significantly more sensitive

  12. Correction of rectal sacculation through lateral resection in dogs with perineal hernia - technique description

    P.C. Moraes

    2013-06-01

    Full Text Available The occurrence of perineal hernias in dogs during routine clinical surgery is frequent. The coexistence of rectal diseases that go undiagnosed or are not correctly treated can cause recurrence and postoperative complications. The objective of this report is to describe a surgical technique for treatment of rectal sacculation through lateral resection in dogs with perineal hernia, whereby restoring the rectal integrity.

  13. The Clinical Utility of Rectal Gas Distension F-18 FDG PET/CT

    Kim, Jin Suk; Lim, Seok Tae; Jeong, Young Jin; Kim, Dong Wook; Jeong, Hwan Jeong; Sohn, Myung Hee [Chonbuk National University Medical School and Hospital, Jeonju (Korea, Republic of)

    2009-12-15

    The aim of this study was to evaluate the clinical value of rectal gas distension F-18 FDG PET/CT imaging for the differentiation of the rectal focal uptake lesions. Twenty four patients (M:F=11:13, Age 62.8{+-}12.4 years) underwent rectal gas distension F-18 FDG PET/CT, prospectively: initial image at 50-60 min after the intravenous injection of F-18 FDG and rectal distension image after the infusion of air through the anus. Focally increased uptake lesions on initial images but disappeared on rectal distension images defined a physiological uptake. For the differential evaluation of persistent focal uptake lesions on rectal distension images, colonoscopy and histopathologic examination were performed. Among the 24 patients, 27 lesions of focal rectal uptake were detected on initial images of F-18 FDG PET/CT. Of these, 7 lesions were able to judge with physiological uptake because the focal increased uptake disappeared from rectal distension image. Remaining 3 lesions were non-rectal lesions (2 lesions: rectovesical space, 1 lesion: uterine myoma). Among 17 lesions which was showed persistent increased uptake in rectal distension image, 15 lesions were confirmed as the malignant tumor (SUVmax=15.9{+-}6.8) and 2 lesions were confirmed as the benign lesions including adenoma and inflammatory disease. The rectal distension F-18 FDG PET/CT imaging could be an important noninvasive method for the differentiation of malignant and benign focal rectal uptake lesions including physiologic uptake.

  14. Quality of life after rectal resection for cancer, with or without permanent colostomy

    Pachler, Jørn; Wille-Jørgensen, Peer

    2012-01-01

    For almost one hundred years abdominoperineal excision has been the standard treatment of choice for rectal cancer. With advances in the techniques for rectal resection and anastomosis, anterior resection with preservation of the sphincter function has become the preferred treatment for rectal ca......, patients having sphincter-preserving operations may experience symptoms affecting their quality of life that are different from stoma-patients....

  15. Human Collagen Injections to Reduce Rectal Dose During Radiotherapy

    Objectives: The continuing search for interventions, which address the incidence and grade of rectal toxicities associated with radiation treatment of prostate cancer, is a major concern. We are reporting an investigational trial using human collagen to increase the distance between the prostate and anterior rectal wall, thereby decreasing the radiation dose to the rectum. Methods: This is a pilot study evaluating the use of human collagen as a displacing agent for the rectal wall injected before starting a course of intensity-modulated radiotherapy (IMRT) for prostate cancer. Using a transperineal approach, 20 mL of human collagen was injected into the perirectal space in an outpatient setting. Computerized IMRT plans were performed pre- and postcollagen injection, and after a patient completed their radiotherapy, to determine radiation dose reduction to the rectum associated with the collagen injection. Computed tomography scans were performed 6 months and 12 months after completing their radiotherapy to evaluate absorption rate of the collagen. All patients were treated with IMRT to a dose of 75.6 Gy to the prostate. Results: Eleven patients were enrolled into the study. The injection of human collagen in the outpatient setting was well tolerated. The mean separation between the prostate and anterior rectum was 12.7 mm. The mean reduction in dose to the anterior rectal wall was 50%. All men denied any rectal symptoms during the study. Conclusions: The transperineal injection of human collagen for the purpose of tissue displacement is well tolerated in the outpatient setting. The increased separation between the prostate and rectum resulted in a significant decrease in radiation dose to the rectum while receiving IMRT and was associated with no rectal toxicities.

  16. The Effects of Star Strategy of Computer-Assisted Mathematics Lessons on the Achievement and Problem Solving Skills in 2nd Grade Courses

    Jale İPEK

    2013-12-01

    Full Text Available The aim of research is to determine the effect of STAR strategy on 2nd grade students’ academic achievement and problem solving skills in the computer assisted mathematics instruction. 30 students who attend to 2nd grade course in a primary school in Aydın in 2010-2011 education year join the study group. The research has been taken place in 7 week. 3 types of tests have been used as means of data collecting tool, “Academic Achievement Test”, “Problem Solving Achievement Test” and “The Evaluation Form of Problem Solving Skills”. At the end of research students’ views about computer assisted mathematics instruction were evaluated. It has been examined that whether the differences between the scores of pre-test and post-test are statistically meaningful or not. According to the results, a positive increase on the academic achievement and problem solving skills has been determined at the end of the education carried out with STAR strategy.

  17. Structural and magnetic study of order-disorder behavior in the double perovskites Ba2Nd1-xMnxMoO6.

    Coomer, Fiona C; Cussen, Edmund J

    2014-01-21

    The synthesis and structural and magnetic characterization of the site-ordered double perovskites, Ba2Nd1-xMnxMoO6, 0 0.3, no deviation from the ideal cubic Fm3̅m symmetry is observed. Furthermore, dc-susceptibility measurements confirm that Mn(2+) is being doped onto the Nd(3+) site, and the associated oxidation of Mo(5+) to Mo(6+). For all compositions, the Curie-Weiss paramagnetic behavior above 150 K indicates negative Weiss constants that range from -24(2) and -85(2) K. This net antiferromagnetic interaction is weakest when x ≈ 0.5, where the disorder in cation site occupancy and competition with ferromagnetic interactions is the greatest. Despite these strong antiferromagnetic interactions, there is no evidence in the dc-susceptibility of a bulk cancellation of spins for x > 0.05. Low-temperature neutron diffraction measurements indicate that there is no long-range magnetic order for 0.1 ≤ x < 0.9. Ba2Nd0.10Mn0.90MoO6 exhibits additional Bragg scattering at 2 K, indicative of long-range antiferromagnetic ordering of the Mn(2+) cations, with a propagation vector k = (1/2, 1/2, 1/2). The scattering intensities can be modeled using a noncollinear magnetic structure with the Mn(2+) moments orientated antiferromagnetically along the four different ⟨111⟩ directions. PMID:24392887

  18. Measurements of oscillator strengths of the 2p{sup 5}({sup 2}P{sub 1/2})nd J = 2, 3 autoionizing resonances in neon

    Mahmood, Shaukat; Amin, Nasir; Sami-ul-Haq; Shaikh, Nek M; Hussain, Shahid; Baig, M A [Atomic and Molecular Physics Laboratory, Department of Physics, Quaid-i-Azam University, Islamabad 45320 (Pakistan)

    2006-05-14

    Oscillator strengths of the 2p{sup 5}({sup 2}P{sub 1/2})nd J = 2, 3 autoionizing resonances in neon have been determined using a dc discharge plasma in conjunction with an Nd:YAG pumped dye laser system. The excited states are approached using two-step laser excitation via 2p{sup 5}3p'[1/2]{sub 1}, 2p{sup 5}3p'[3/2]{sub 1} and 2p{sup 5}3p'[3/2]{sub 2} intermediate states which are accessed from the 2p{sup 5}3s [1/2]{sub 2} metastable state, populated by the discharge in the hollow cathode lamp. The f-values have been determined for the nd'[3/2]{sub 2}, nd'[5/2]{sub 2} and nd'[5/2]{sub 3} series following the {delta}K = {delta}J = +{delta}l selection rule. Employing the saturation technique the photoionization cross section at the 2p{sup 5} {sup 2}P{sub 1/2} ionization threshold is determined as 5.5(6) Mb and consequently the f-values of the nd' J = 2, 3 autoionizing resonances have been extracted.

  19. Hyperfine structure and lifetime measurements in the 4s2nd 2D3/2 Rydberg sequence of Ga I by time-resolved laser spectroscopy

    Liu, Chunqing; Tian, Yanshan; Yu, Qi; Bai, Wanshuang; Wang, Xinghao; Wang, Chong; Dai, Zhenwen

    2016-05-01

    The hyperfine structure (HFS) constants of the 4s2nd 2D3/2 (n=6-18) Rydberg sequence and the 4s26p 2P3/2 level for two isotopes of 69Ga and 71Ga atoms were measured by means of the time-resolved laser-induced fluorescence (TR-LIF) technique and the quantum beat method. The observed hyperfine quantum beat spectra were analyzed and the magnetic-dipole HFS constants A as well as the electric-quadrupole HFS constants B of these levels were obtained by Fourier transform and a program for multiple regression analysis. Also using TR-LIF method radiative lifetimes of the above sequence states were determined at room temperature. The measured lifetime values range from 69 to 2279 ns with uncertainties no more than 10%. To our knowledge, the HFS constants of this Rydberg sequence and the lifetimes of the 4s2nd 2D3/2 (n=10-18) levels are reported for the first time. Good agreement between our results and the previous is achieved.

  20. Carbon dioxide emissions and the overshoot ratio change resulting from the implementation of 2nd Energy Master Plan in South Korea

    Yeo, M. J.; Kim, Y. P.

    2015-12-01

    The direction of the energy policies of the country is important in the projection of environmental impacts of the country. The greenhouse gases (GHGs) emission of the energy sector in South Korea is very huge, about 600 MtCO2e in 2011. Also the carbon footprint due to the energy consumption contributes to the ecological footprint is also large, more than 60%. Based on the official plans (the national greenhouse gases emission reduction target for 2030 (GHG target for 2030) and the 2nd Energy Master Plan (2nd EMP)), several scenarios were proposed and the sensitivity of the GHG emission amount and 'overshoot ratio' which is the ratio of ecological footprint to biocapacity were estimated. It was found that to meet the GHG target for 2030 the ratio of non-emission energy for power generation should be over 71% which would be very difficult. We also found that the overshoot ratio would increase from 5.9 in 2009 to 7.6 in 2035. Thus, additional efforts are required to reduce the environmental burdens in addition to optimize the power mix configuration. One example is the conversion efficiency in power generation. If the conversion efficiency in power generation rises up 50% from the current level, 40%, the energy demand and resultant carbon dioxide emissions would decrease about 10%. Also the influence on the environment through changes in consumption behavior, for example, the diet choice is expected to be meaningful.

  1. A study on trait anger – anger expression and friendship commitment levels of primary school 2nd stage students who play – do not play sports

    Hüseyin Kırımoğlu

    2010-09-01

    Full Text Available The aim of this research was to investigate the state of trait anger-anger expression and friendship commitment levels depending on the fact whether 2nd-stage-students in primary schools played sports or not.Personal Information Form, Trait Anger-Anger Expression Scales and Inventory of Peer Attachment were used in order to collect the data.The population of the research was consisted of the students who studied in 2nd stage of 40 primary state schools that belonged to National Education Directorate of Hatay Province between 2009-2010 academic year. Sample group was made up by 853 students of 21 primary schools who were selected from the population (262 boy students and 149 girl students who played sports as registered players; 233 boy students and 209 girl students who did not play sports..To sum up; the comparison of the scores of trait anger and external anger of the participant students who played sports yielded a statistically significant difference in terms of sex variable (p< 0.05. As for the sedentary group, boys had higher scores of internal anger and external anger than girls. In the comparison of the scores of friendship commitment in sedentary students in terms of sex variable, it was found out that there was a statistically significant difference between girls and boys, which was in favour of boys (p<0.05.

  2. Assessment of primary school students’ level of understanding the concepts of 2nd grade life sciences course based on different variables

    Altıntaş Gülşen

    2016-01-01

    Full Text Available The course of Life Sciences is one of the pivot courses taught in the first three years of primary school. Ensuring children get to know their environment and gain correct information related to their problems by making them investigate their natural and socio-cultural environment as well as providing them with necessary information, skills and behaviors for environmental adaptation are among the main purposes of Life Sciences course. The concepts to be instilled in students in line with these purposes are important. Since concepts are mostly intellectual and non-physical, they can only exist tangibly through examples. This study aims to assess Primary School Students’ Level of Understanding the Concepts of 2nd Grade Life Sciences Course Based on Different Variables. 17 concepts included in the 2nd Grade Life Sciences course within the subject of School Excitement were addressed within the study, and students were requested to define and exemplify these concepts. A total of 102 students from five different primary schools of upper-middle and lower socioeconomic classes located in Manisa and Istanbul were included in the study in line with the intentional maximum diversity sample selection. The answers given by students for each concept were categorized and analyzed in terms of liking or disliking home, school, technology and the course of Life Sciences.

  3. Microstructure imaging of human rectal mucosa using multiphoton microscopy

    Liu, N R; Chen, J X; Zhuo, S M; Zheng, L Q; Jiang, X S [Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou (China); Chen, G [Department of Pathology, Fujian Provincial Tumor Hospital, Fuzhou (China); Yan, J, E-mail: chenjianxin@fjnu.edu.cn, E-mail: ynjun@yahoo.com [Department of Surgery, Fujian Provincial Tumor Hospital, Fuzhou (China)

    2011-01-01

    Multiphoton microscopy (MPM) has high resolution and sensitivity. In this study, MPM was used to image microstructure of human rectal mucosa. The morphology and distribution of the main components in mucosa layer, absorptive cells and goblet cells in the epithelium, abundant intestinal glands in the lamina propria and smooth muscle fibers in the muscularis mucosa were clearly monitored. The variations of these components were tightly relevant to the pathology in gastrointestine system, especially early rectal cancer. The obtained images will be helpful for the diagnosis of early colorectal cancer.

  4. Per-rectal portal scintigraphy in chronic liver diseases

    Portal circulation has been evaluated by per-rectal portal scintigraphy in 21 controls and in 30 pts affected by chronic liver diseases. Tc99m-pertechnetate (10 mci) was given through a Nelaton's catheter in the upper rectum; a per-rectal portal shunt index (SI) was calculated. A relevant overlap is evident between controls and CHP pts; no overlap exists between controls and B or C graded cirrhosis. We conclude that the technique may be suggested to monitor the course of chronic liver diseases and different therapeutic regimens. (orig.)

  5. Rectal fist insertion. An unusual form of sexual behavior.

    Shook, L L; Whittle, R; Rose, E F

    1985-12-01

    Rectal fist insertion (fist fucking) is an uncommon and potentially dangerous sexual practice. This is usually a homosexual activity, but can also be a heterosexual or an autoerotic practice. One known death has been reported associated with rectal fist insertion, in which the complications of anal and colonic tears and bleeding had occurred (see Editor's note). The possibility of drug overdose is also probable, as drugs and alcohol are commonly introduced into the rectum to promote sphincter relaxation and to ease the discomfort of anal dilatation. PMID:4072987

  6. Health-Related Quality of Life after surgery for primary advanced rectal cancer and recurrent rectal cancer

    Thaysen, Henriette Vind; Jess, Per; Laurberg, Søren

    2012-01-01

    Aim: A review of the literature was undertaken to provide an overview of Health-related quality of life (HRQoL) after surgery for primary advanced or recurrent rectal cancer and to outline proposals for future HRQoL studies in this area. Method: A systematic literature search was undertaken. Only...... studies concerning surgery for primary advanced or recurrent rectal cancer and describing methods used for measuring HRQoL were considered. Results Seven studies were identified including two prospective longitudinal, three cross-sectional and two based on qualitative data. Global quality of life...... time of impaired HRQoL and also if this is different after surgery for locally advanced or recurrent disease than after total mesorectal excision used for earlier tumours.. Conclusion Several aspects of HRQoL are impaired for a variable time after treatment for locally advanced or recurrence of rectal...

  7. Review of the scientific sessions of the European radiological congress in Bordeaux

    This review of the 5th Congress of the European Radiological Society and, simultaneously, 2nd Congress of ESTRO (European Society of Therapeutic Radiology and Oncology) in Bordeaux from September 5th-10th, 1983, has two objectives, viz. to report on the course of the congress and to comment important substantive aspects. This is done from the viewpoint of the physicist working in the field bordering on radiology. It thus seems justified to restrict this review to a choice of aspects compising technical and methodical consequences. The chronological sequence of the 57 scientific meetings serves as far as possible as a guideline. (orig./BWU)

  8. European Decommissioning Academy (EDA). Ready to start

    Slugen, Vladimir [Slovak University of Technology, Bratislava (Slovakia). Inst. of Nuclear and Physical Engineering

    2015-02-15

    According to analyses presented at EC meeting focused on decommissioning organized at 11 September 2012 in Brussels, it was stated that at least 2,000 new international experts for decommissioning will be needed in Europe up to 2025, which means about 150 each year. The article describes the European Decommissioning Academy (EDA) which is prepared for the first term in June 2015 in Slovakia. The main goal is a creation of new nuclear experts generation for decommissioning via the Academy, which will include lessons, practical exercises in laboratories as well as 2 days on-site training at NPP V-1 in Jaslovske Bohunice (Slovakia). Four days technical tour via most interesting European decommissioning facilities in Switzerland and Italy are planned as well. After the final exam, there is the option to continue in knowledge collection via participation at the 2nd Eastern and Central European Decommissioning (ECED) conference in Trnava (Slovakia). We would like to focus on VVER decommissioning issues because this reactor type is the most distributed design in the world and many of these units are actually in decommissioning process or will be decommissioned in the near future.

  9. European Decommissioning Academy (EDA). Ready to start

    According to analyses presented at EC meeting focused on decommissioning organized at 11 September 2012 in Brussels, it was stated that at least 2,000 new international experts for decommissioning will be needed in Europe up to 2025, which means about 150 each year. The article describes the European Decommissioning Academy (EDA) which is prepared for the first term in June 2015 in Slovakia. The main goal is a creation of new nuclear experts generation for decommissioning via the Academy, which will include lessons, practical exercises in laboratories as well as 2 days on-site training at NPP V-1 in Jaslovske Bohunice (Slovakia). Four days technical tour via most interesting European decommissioning facilities in Switzerland and Italy are planned as well. After the final exam, there is the option to continue in knowledge collection via participation at the 2nd Eastern and Central European Decommissioning (ECED) conference in Trnava (Slovakia). We would like to focus on VVER decommissioning issues because this reactor type is the most distributed design in the world and many of these units are actually in decommissioning process or will be decommissioned in the near future.

  10. European Peacebuilding

    Rodt, Annemarie Peen

    2015-01-01

    This contribution argues that the peace that has emerged between and increasingly within European states is a historical achievement. A variety of different peace initiatives have brought Europe to where it is today, but a particularly significant player in this process has been and still is the...

  11. Benign (solitary) ulcer of the rectum - another cause for rectal stricture

    Benign rectal ulcer syndrome is an uncommon cause of lower gastrointestinal bleeding. Patients may present with mild, often recurrent, rectal bleeding frequently ascribed to hemorrhoids. Barium enema may be normal during the early, nonulcerative phase of proctitis. Single (or multiple) uclers with or without rectal stricture are the hallmarks of the radiographic diagnosis. Radiologic demonstration of the ulcer(s) is not required, however, for the diagnosis. Benign rectal ulcer should be included in the differential diagnosis of benign-appearing rectal strictures. (orig.)

  12. Association between polycyclic aromatic hydrocarbons and human rectal tumor or liver cancer

    Guohong Jiang; Limin Lun; Liyuan Cong

    2012-01-01

    Objective: The aim of this study was to investigate the effect of polycyclic aromatic hydrocarbons (PAHs) in rectal carcinoma and hepatocarcinoma genesis. Methods: The PAHs in the human rectal cancer and liver cancer tissues, the adjacent tissues and homologous tissues without rectal cancer or liver cancer were extracted by ultrasonic wave. The extracts were then cleaned up and enriched by solid phase extraction, analyzed by high performance liquid chromatography (HPLC) with fluorescence spectroscopy. Results: Four kinds of PAHs were detected in human rectal and hepatic tissues. The contents of pyrene, 2-methylanthracene and benzo (a) pyrene in both rectal cancer tissues and adjacent homologous tissues were higher than rectal tissues without rectal cancer, the differences were statistically significant (P 0.05). The differences of the content of each PAHs between rectal cancer and adjacent tissue were not significant (P > 0.05). The contents of the four PAHs in the three kinds of liver tis-sues were not statistically significant (P > 0.05). Conclusion: PAHs are found in human rectal tissues or hepatic tissues. The contents of PAHs in human rectal tissue may have an effect on the occurrence of human rectal cancer while the contents of PAHs in human hepatic tissues may have not ones.

  13. Rectal angiolipoma: A case report and review of literature

    Sabite Kacar; Sedef Kuran; Tulay Temucin; Bulent Odemis; Nilufer Karadeniz; Nurgul Sasmaz

    2007-01-01

    Angiolipoma is a rare vascular variant of the benign lipomatous tumors and is generally seen in subcutaneous tissues. We report a 70-year-old female with abdominal distension not related to rectal small polypoid mass with peduncule described as angiolipoma by histologically,and review the literature.

  14. Treatment of locally advanced rectal cancer: Controversies and questions

    Atthaphorn Trakarnsanga; Suthinee Ithimakin; Martin R Weiser

    2012-01-01

    Rectal cancers extending through the rectal wall,or involving locoregional lymph nodes (T3/4 or N1/2),have been more difficult to cure.The confines of the bony pelvis and the necessity of preserving the autonomic nerves makes surgical extirpation challenging,which accounts for the high rates of local and distant relapse in this setting.Combined multimodality treatment for rectal cancer stage Ⅱ and Ⅲ was recommended from National Institute of Health consensus.Neoadjuvant chemoradiation using fluoropyrimidine-based regimen prior to surgical resection has emerged as the standard of care in the United States.Optimal time of surgery after neoadjuvant treatment remained unclear and prospective randomized controlled trial is ongoing.Traditionally,6-8 wk waiting period was commonly used.The accuracy of studies attempting to determine tumor complete response remains problematic.Currently,surgery remains the standard of care for rectal cancer patients following neoadjuvant chemoradiation,whereas observational management is still investigational.In this article,we outline trends and controversies associated with optimal pre-treatment staging,neoadjuvant therapies,surgery,and adjuvant therapy.

  15. Whither papillon? Future directions for contact radiotherapy in rectal cancer

    Lindegaard, J; Gerard, J P; Sun Myint, A;

    2007-01-01

    Although contact radiotherapy was developed 70 years ago, and is highly effective with cure rates of over 90% for early rectal cancer, there are few centres that offer this treatment today. One reason is the lack of replacement of ageing contact X-ray machines, many of which are now over 30 years...

  16. Sexual function in females after radiotherapy for rectal cancer

    Background. Knowledge about female sexual problems after pre- or postoperative (chemo-)radiotherapy and radical resection of rectal cancer is limited. The aim of this study was to compare self-rated sexual functioning in women treated with or without radiotherapy (RT+ vs. RT?), at least two years after surgery for rectal cancer. Methods and materials. Female patients diagnosed from 1993 to 2003 were identified from a national database, the Norwegian Rectal Cancer Registry. Eligible patients were without recurrence or metastases at the time of the study. The Sexual function and Vaginal Changes Questionnaire (SVQ) was used to measure sexual functioning. Results. Questionnaires were returned from 172 of 332 invited and eligible women (52%). The mean age was 65 years (range 42-79) and the time since surgery for rectal cancer was 4.5 years (range 2.6-12.4). Sexual interest was not significantly impaired in RT+ (n=62) compared to RT? (n=110) women. RT+ women reported more vaginal problems in terms of vaginal dryness (50% vs. 24%), dyspareunia (35% vs. 11%) and reduced vaginal dimension (35% vs. 6%) compared with RT? patients; however, they did not have significantly more worries about their sex life. Conclusion. An increased risk of dyspareunia and vaginal dryness was observed in women following surgery combined with (chemo-)radiotherapy compared with women treated with surgery alone. Further research is required to determine the effect of adjuvant therapy on female sexual function

  17. Laparoscopic surgery for lower rectal cancer with neoadjuvant preoperative chemoradiotherapy

    Neoadjuvant chemoradiotherapy (NACRT) is an accepted standard treatment for low rectal advanced cancer to improve the local control in western countries. Recently laparoscopy has been recognized as an excellent tool from a view point of its magnification. Therefore, we have performed many laparoscopic surgeries for locally advanced rectal cancer after NACRT, We evaluated our results in this study. We studied 100 patients underwent surgery for locally advanced low rectal cancer after NACRT. Rate of sphincter preserving surgery was 74%. Rate of laparoscopic surgery was 95%. Positive distal resection margins were not identified in all patients. Positive circumferencial resection margins were identified in only two patients. The pathological complete response rate was 15%. The rate of postoperative complications was 15%. Complications were as follows: wound infection (9%), pelvic abscess (2%), ileus (2%) and others (2%), however without mortality. Anastomotic leakage was not observed in all cases, even though we routinely created diverting stoma. Laparoscopic surgery for low rectal cancer after NACRT is considered to be a safe and feasible procedure. (author)

  18. Multicenter evaluation of rectal cancer reimaging post neoadjuvant (MERRION) therapy.

    Hanly, Ann M

    2014-04-01

    The aim of this study was to evaluate the utility of reimaging rectal cancer post-CRT (chemoradiotherapy) with magnetic resonance (MR) imaging of the pelvis for local staging and computed tomography of thorax, abdomen, and pelvis (CT TAP) to identify distant metastases.

  19. Single-Access Laparoscopic Rectal Surgery Is Technically Feasible

    Siripong Sirikurnpiboon

    2013-01-01

    Full Text Available Introduction. Single-access laparoscopic surgery (SALS has been successfully introduced for colectomy surgery; however, for mid to low rectum procedures such as total mesorectal excision, it can be technically complicated. In this study, we introduced a single-access technique for rectum cancer operations without the use of other instruments. Aims. To show the short-term results of single-access laparoscopic rectal surgery in terms of pathologic results and immediate complications. Settings and Design. Prospective study. Materials and Methods. We selected middle rectum to anal canal cancer patients to undergo single-access laparoscopic rectal resection for rectal cancer. All patients had total mesorectal excisions. An umbilical incision was made for the insertion of a single multichannel port, and a mesocolic window was created to identify the inferior mesenteric artery and vein. Total mesorectal excision was performed. There were no perioperative complications. The mean operative time was 269 minutes; the median hospital stay was 7 days; the mean wound size was 5.5 cm; the median number of harvested lymph nodes was 15; and all patients had intact mesorectal capsules. Statistical Analysis Used. Mean, minimum–maximum. Conclusion. Single-access laparoscopic surgery for rectal cancer is feasible while oncologic principles and patient safety are maintained.

  20. Rectal Sensitivity in Diabetes Patients with Symptoms of Gastroparesis

    Eirik Søfteland

    2014-01-01

    Full Text Available In a clinical setting, diabetic autonomic complications (cardiac, gastrointestinal, urogenital, etc. are often handled as separate entities. We investigated rectal sensitivity to heat, mechanical distension, and electrical stimulations in 20 patients with diabetes and symptoms of gastroparesis, to evaluate the extent of visceral neuronal damage. Furthermore, to evaluate the relation between the nervous structures we examined gastric emptying and cardiac autonomic function with the hypothesis being an association between these. We found that 60% of patients had delayed gastric empting. Rectal hyposensitivity was a general finding as they tolerated 67% higher thermal, 42% more mechanical, and 33% higher electrical current intensity compared to healthy controls. In patients, most heart rate variability parameters were reduced; they reported significantly more gastrointestinal symptoms and a reduced quality of life in all SF-36 domains. Shortened RR interval correlated with reduced rectal temperature sensitivity, and gastric retention rate was negatively associated with symptoms of nausea and vomiting. To conclude, in these patients with signs and symptoms of diabetic gastroparesis, rectal sensitivity was reduced, and heart rate variability was impaired. Thus, we suggest regarding diabetic autonomic neuropathy as a diffuse disorder. Symptoms of widespread autonomic dysfunction and sensory disorders should be expected and treated in these patients.