International Nuclear Information System (INIS)

Plasma triglyceride turnover was measured during steady-state conditions in 22 postoperative patients. Nine had received nutritional support with an enteral regimen, seven had received an equivalent regimen as continuous parenteral nutrition, and six received the same parenteral regimen as a cyclical infusion. After 5 days of nutritional support, each patient received an intravenous bolus of tritiated glycerol. Plasma radiolabeled triglyceride content was measured during the subsequent 24 hours. The data were analyzed by means of a simple deterministic model of plasma triglyceride kinetics and compared with the results obtained by stochastic analysis. The rates of hepatic triglyceride secretion obtained by deterministic analysis were higher than those obtained by the stochastic approach. However, the mode of delivery of the nutritional regimen did not affect the rate of hepatic triglyceride secretion ...

UK PubMed Central (United Kingdom)

Bolus infusion of insulin along with a meal is a standard procedure with continuous subcutaneous insulin infusion. Modern insulin pumps allow applying this bolus in four different ways: infusion of...Full Text Available

Science.gov (United States)

A new method of administration of an opioid was recently registered: fentanyl transdermal (brand name: Durogesic), intended particularly for the indication range 'pain in cancer'. Fentanyl is lipid-soluble so that deposition in the skin takes place and the biological half-life is approximately 20 hours after removal of the plaster. It is safe to start on a basis of an equianalgesic conversion of 100:1 in relation to oral morphine, although this may entail some risk of fentanyl under dosage. The dose adjustment time is 12-24 hours before a constant fentanyl level is reached; therefore, after attaching the first sticking plaster, the original morphine dose should be continued for another 12 hours. In addition, the patient may, if necessary, be given supplementary morphine preferably as a short-acting drug. There seems to be no clear indication for transdermal fentanyl either in neuropathic pain or in chronic benign pain. ...

Energy Technology Data Exchange (ETDEWEB)

3-Quinuclidinyl benzilate (QNB) is a potent muscarinic antagonist that binds to muscarinic acetylcholine receptors. Iodination of QNB is difficult because it contains rings that are deactivated, while phenol rings are activated. The purpose of this research is to develop an appropriate method for the iodination of QNB at no-carrier-added concentrations of /sup 125/I/NaI. Phenol was chose as the test compound for direct iodination by adding chloramine T and nonradioactive sodium iodide to the phenol in a phosphate buffer and methanol system. A simple method to radioiodinate QNB at several concentrations was developed in situ in the presence of QNB, thallic trifluoroacetate /sup 125/I/NaI, /sup 127/I/NaI, and aluminium chloride. Using milligram amounts of QNB (7.12 x 10/sup -6/ moles), three reaction steps were involved: QNB was reacted with thallic trifluoroacetate at 60/sup 0/C for 24 hours, then radioactive /sup 125/I/NaI and aluminium ...

International Nuclear Information System (INIS)

adult males and females, less than 24 hours old, of the spiny bollworm, Earias Insulana boisd. were irradiated with sub sterilizing doses of 50,80,100 and 150 gray (Gy). treated moths were out crossed with normal adults and observed for their ability to reproduce. inherited deleterious effects resulting from irradiation of p_1 moths were recorded for several generations. the reduction in both fecundity and egg viability increased by increasing the dose applied to p_1 adult moths .at all tested doses, the females were more radiosensitive than males, as for reduction in fecundity and egg viability. the progeny from irradiated parental females are not as sterile as the progeny from irradiated parental males. the reduction of egg hatching continued in the progeny of irradiated males through F_1 and to lesser extent through F_2 .on the other hand , irradiation of P_1 females reduced the rate of egg hatching among parental ...

UK PubMed Central (United Kingdom)

The clinical signs and postmortem findings in sheep from two flocks accidentally poisoned with monensin are described. Clinical signs began within 24 hours of exposure to monensin. In the acute stages...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Airbag pressure vessels for the north-American market mainly are made by forging and by the use of steel alloys. In Europe aluminum alloys are common and the manufacturing process is extrusion of circular blanks - made from cold rolled plates - in a form applying a 100 t press at room temperature. Then by heat treatment the strength/hardness of the material is properly adjusted and after that the pressure vessel parts have to be continuously inspected with an inspection and handling cycle time of 3 s. Inspection of the axis-symmetric parts is asked for surface breaking extrusion defects as well as for surface parallel delaminations in the bulk volume. Furthermore, the material strength is a quality characteristic that has to be nondestructively registered and documented. The inspection is performed by eddy current probes and an EMAT, of which the eddy current impedance measurements are used for surface breaking extrusion defect detection and sizing (single ...

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This award provided for an automated computer-controlled goniometer/diffractometer/manipulator with hot and cold stages and data acquisition system that was interfaced with the high resolution Scienta ESCA-300 X-ray photoelectron spectrometer at Lehigh University. The automation allows angular dependent X-ray photoelectron spectroscopy (XPS) and ultraviolet photoelectron spectroscopy (UPS) data to be accurately and rapidly collected without the very time-consuming and labor-intensive manual method that was previously required. It also provides for automated multi-sample analyses, collecting both wide survey scans and selected binding energy range analyses, with complete computer control and data storage. This allows 24 hour data collection without requiring the continuous presence of operators. The overall result is a greater productivity for the XPS laboratory, approximately doubling the output of the laboratory. While the ...

International Nuclear Information System (INIS)

The activity of tyrosine aminotransferase (TAT) in the liver of mice subjected simultaneously to ionizing radiation and to local inflammatory process showed in the first 24 hours of the experiment statistically significant changes resulting from summation of the harmful effects of both factors. In the second 24-hour period an evident tendency was observed for return of a normal circadian rhythm of the enzyme. This points to presence of an endogenous mechanism of suppression of the manifestations of significant desynchronization of the circadian rhythm. The paper contains also a trial of mathematical analysis of changes in TAT activity in the circadian rhythm, a description and analysis or the suppression process, qualitative and quantitative determination of the phenomenon of cumulation of the effects of powerful stress factors acting on the animal organism. The obtained results were compared with the ...

UK PubMed Central (United Kingdom)

BackgroundSeveral studies have demonstrated the efficacy of artemisinin-combination therapy (ACT) across malaria zones of the world. Fixed dose ACT with shorter courses and fewer...Full Text Available

UK PubMed Central (United Kingdom)

Background/Objective:Three patients with spinal cord injury (SCI) and 3 able-bodied (AB) patients were infused with naloxone during a study to examine their neuroendocrine...Full Text Available

Medline Plus

... of the Taperloc Microplasty stem and E-poly antioxidant-infused technology during a hip replacement through the ...

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The effects of muscarinic agonists and diisopropylfluorophosphate (DFP) on muscarinic receptor density and muscarinic receptor-mediated responses was assessed in mouse brain and mouse neuroblastoma cells (clone N1E-115). Utilizing the antagonist ({sup 3}H)quinuclidinyl benzilate (({sup 3}H)QNB), there was no difference in the maximal binding capacity (B{sub max}) or equilibrium dissociation constant (K{sub d}) between untreated and 24 hour DFP-treated mice. However, one administration of DFP produced a 24% and 33% decrease in B{sub max} measured by ({sup 3}H)N-methylscopolamine (({sup 3}H)NMS) after 18 and 24 hours which was rapidly reversible within 36 hours after DFP treatment. The loss of ({sup 3}H)NMS binding sites following acute DFP treatment was not accompanied by a change in a particular muscarinic receptor binding conformation. Furthermore, the magnitude of muscarinic receptor-mediated ...

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Installation of new Shortwave Spectrometer for permanent operation at SGP - In May 2006 the new ShortWave Spectrometer (SWS) was installed in the Optical Trailer at the Southern Great Plains Central Facility SGP on 27 April 2006. The SWS began full operation 28 April 2006 and has run continuously to the present. Over 25 GB of spectra has been collected, calibrated and archived. 3-D radiative transfer simulations - Retrieved fields of cloud optical thickness and effective radius to from the MODIS Airborne Simulator were used to reproduce 3D cloud fields that were used a input to 3D radiative transfer simulations and then compared with simultaneous Solar Spectral Flux Radiometer (SSFR) spectral irradiance measurements. The influence of both horizontal and vertical cloud structure, using accurate versus approximated optical properties in the radiative transfer model on the modeled irradiance was examined, as was the influence of using the full phase function versus ...

British Library Electronic Table of Contents (United Kingdom)

Summary The purpose of this study was to evaluate the efficacy of postoperative adjuvant chemotherapy with FOLFOX regimen on the outcome after LT for HCC patients who did not meet the Milan criteria. Ninety-five consecutive HCC patients with liver cirrhosis undergoing LT were enrolled. Fifty-eight who did not meet the Milan criteria were randomized to open-label treatment with or without adjuvant chemotherapy after LT (n?=?29/group). The FOLFOX chemotherapy protocol comprised 3-week cycles of oxaliplatin 100?mg/m2 on day 1, leucovorin (calcium folinate, CF) 200?mg/m2 on day 1 followed by 3-day, and 5-fluorouracil (5-FU) 2000?mg/m2 as a 48-h continuous infusion, for up to six courses in the 1st year after transplantation. Median survival was extended by 4.57?months by combination chemothera...

British Library Electronic Table of Contents (United Kingdom)

Summary The antioxidant properties and toxicity profile of roasted noni (Morinda citrifolia L.) leaf infusion were evaluated. The 2,2-diphenylpicrylhydrazyl (DPPH) radical scavenging activity was greater than green tea infusion (81.6 +- 0.9% vs. 57.5 +- 1.8%, P < 0.001). The mean quercetin and kaempferol contents of roasted noni leaf infusion, as prepared by the consumer, were 0.24 +- 0.01 and 0.14 +- 0.01 mg mL-1, respectively. Tannic acid content was 10 +- 1 mg mL-1. The infusion was non-mutagenic in the reverse mutation test in Salmonella typhimurium and did not induce primary DNA damage in E. coli PQ37. Further, no significant primary DNA damage was induced by 5,15-dimethylmorindol, which was the only detectable anthraquinone in noni leaves. The infusion was not cytotoxic in the 24 h b...

UK PubMed Central (United Kingdom)

ContextCorticotropin-releasing hormone (CRH), through the hypothalamic pituitary adrenal (HPA) axis and other brain stress systems, is involved in the emotional dysregulation...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Ba, Cd, Cr, Cu, Fe, Ni, Pb and Zn were determined in birch leaves (Folium Betulae), dandelion roots (Radix Taraxacae), hawthorn blossom (Inflorescentia Crataegi) and their infusions by graphite furnace atomic absorption spectrometry (GFAAS) after microwave digestion of plant samples. Infusions were made from herbs according to prescription for patients, provided by the producer of medicine on the package. The results obtained were compared with daily requirements for each element. Results show high content of cadmium in the medicinal plants analyzed. The highest level in infusions was observed for Ni and Zn (over 90% of the total element concentration for Ni and in most cases over 50% for Zn), and the lowest for Cd and Pb. The calculated daily intake of majority of the analyzed elements was very low (under 1% of daily requirements)

Science.gov (United States)

... Rhabdomyosarcoma. (0) 505 POG 8561 Phase II Study of 6- Mercaptopurine Administered as an Intra- 506 venous Infusion ...

Energy Technology Data Exchange (ETDEWEB)

Finland has some 10 million hectares of peatland, accounting for almost a third of its total area. Macroclimatic conditions have varied in the course of the Holocene growth and development of this peatland, and with them the habitats of the peat-forming plants. Temperatures and moisture conditions have played a significant role in determining the dominant species of mire plants growing there at any particular time, the resulting mire types and the accumulation and deposition of plant remains to form the peat. While in a natural state the mires of Finland have functioned as carbon dioxide sinks throughout the post-glacial period, but the ditching of peatland for forestry and agriculture, amounting to some 5,7 million hectares in Finland, has affected their water balance, especially over the last hundred years, and has thereby altered the quantity and species composition of the mire vegetation. The invasion of trees and woody plants to replace the typical mire plants following ditching ...

International Nuclear Information System (INIS)

Objective: To find out safety and efficiency of Misoprostol in cervical ripening and induction of labour to achieve vaginal delivery. Results: From Misoprostol insertion to delivery time was 4-24 hours. Vaginal delivery was achieved in 80.2%, which included spontaneous, forceps and vacuum extraction. Caesarean section rate was 19.7%. Indications for C. Section included Misoprostol unresponsiveness 11% and fetal distress in 8.6%. Oxytocin augmentation was required in 32% of cases. Term babies were 58%. Intrauterine death and neonatal deaths were 9.8% and 8.6% respectively. Hyper stimulation and postpartum haemorrhage was seen in 2.4% and 3.7% of patients respectively. Conclusion: intravaginal Misoprostol is well tolerated and is very effective for the induction of labour in eclampsia. It helps vaginal delivery in toxemic patients, reduces maternal morbidity, mortality and hospital stay. (author)

Science.gov (United States)

Raytheon's Santa Barbara Remote Sensing (SBRS) division designed and built the MTSAT-1R Japanese Advanced Meteorological Imager for the Japanese Ministry of Transport between March, 1999 and July, 2002. In order to meet the stressing requirements of a geosynchronous orbit, a combination of structural, thermal, and optical (STOP) analyses were used to design and optimize the beryllium three-mirror anastigmat (TMA) telescope. This modeling approach was used to characterize and minimize the thermal distortion around local midnight. On-orbit temperatures and structural deformations were predicted using thermal Desktop/SINDA and PATRAN/NASTRAN software, respectively. The resulting optical performance was evaluated using Raytheon developed HEXAGON software. The telescope design was successfully optimized to attain specified visible channel performance for most of the 24 hour orbit.

International Nuclear Information System (INIS)

In the present investigation, the properties of plasma nitrided AISI 304 steel were studied by changing the presence of nitrogen in the gas mixture. The plasma nitriding was performed at temperature -560 deg C, pressure -4 mbar and duration 24 hours. The nitrided samples were characterized by evaluating the phase composition, micro hardness, and diffusion layer thickness. The phase analysis indicates the mixed phases of CrN and Fe_3N, Fe_3N and Fe_4N which has the highest intensity. The results show the glow discharge plasma nitriding in presence of N_2 (80 vol. %) and H_2 (rest) produced higher hardness as well as higher case depth. (author)

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A rare case of primary splenic cyst is shown in a young woman who had a left subcostal abdominal pain. Abdominal echography and CT scan revealed a cyst of the anterior aspect of the spleen. A sorologic test for hidatic disease was negative. On the basis of a presumed diagnostic of nonparasitic cyst, the patient was referred to a laparoscopic decapsulation with excision of the cysts wall not covered by splenic tissue. The patient was discharged 24 hours later. Histological report revealed epidermoid cyst. The laparoscopic approach has being recently considered an effective and less invasive alternative in the treatment of splenic diseases. We demonstrated that it should be considered for the treatment of splenic cysts present in a superficial location, with the advantage of organ preservation. (author)

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT To date the effect of silver-containing wound dressings on biofilms, known to be present in chronic wounds, has not been determined or documented. In this current study, we aimed to determine the antimicrobial effect of a silver-containing dressing on biofilms grown in a chambered slide model. Before the addition of a wound dressing onto a 24-hour biofilm, composed of either Pseudomonas aeruginosa, Enterobacter cloacae, Staphylococcus aureus, or a mixed bacterial community, a fluorescent dye was applied. This enabled the viability of sessile bacteria to be monitored in real-time, using a rapid form of confocal laser scanning microscopy over a contact time period of 48 hours. By analyzing all the three-dimensional data generated from the confocal time-lapse sequences, 90% of all se...

UK PubMed Central (United Kingdom)

Although hippocampal infusions of glucose enhance memory, we have found repeatedly that septal glucose infusions impair memory when γ-aminobutyric acid (GABA) receptors are activated....Full Text Available

International Nuclear Information System (INIS)

Purpose/Objective: The role of programmed cell death (apoptosis) as a cellular response to cancer therapy such as radiation or chemotherapy is the subject of much study, and manipulation of the apoptotic response in tumor cells may be valuable in the treatment of a variety of cancers. Both p53 dependent and independent apoptotic pathways have been identified; p53 is mutated in at least 50 % of human cancers and a majority of radiation resistant tumors contain p53 mutations. This study is designed to examine the induction of programmed cell death in a human colon carcinoma cell line that possesses two mutated p53 alleles. Ionizing radiation alone, or in combination with the chemotherapeutic drug 5-fluorouracil (5-FU), were used to elicit the apoptotic response. This study will focus on whether these treatments can induce a significant apoptotic response in cells that have mutated p53 alleles. Materials and Methods: HT-29 cells were assessed for clonogenic survival after being plated at ...

UK PubMed Central (United Kingdom)

This study examines the effects of intravenous infusion of adenosine and sublingual nitroglycerin on coronary angiograms obtained by current-generation multidetector computed tomography. We assessed...Full Text Available

UK PubMed Central (United Kingdom)

Convection-enhanced delivery (CED) has emerged as a promising method of targeted drug-delivery for treating central nervous system (CNS) disorders, but the influence of brain structure on infusate...Full Text Available

Science.gov (United States)

Federated Search (openSearch) (C. Lynnes); Infusion Process (S. Olding) Metrics Planning & Reporting (R. Ramapriyan); Service & Event Casting (B. Wilson) ...

UK PubMed Central (United Kingdom)

Using 31P-nuclear magnetic resonance, we studied the relationship between myocardial high-energy phosphate content and flux values for the creatine kinase reaction in the living rat under inotropic...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The LS electromagnetic band (1-4 GHz) is widely used both in domestic and industrial domains. Several studies suggested that the biological systems would exhibit a specific sensitivity to the 2.45 GHz microwaves (water resonance frequency). Potential human health hazards and especially a disruption of the cholinergic system have been reported, due to exposure to microwaves even at low power density. This work presents a multi-parametric study of freely moving rat where neuro-physiology was investigated during 70 hours using neurochemical (micro-dialysis technique), electrophysiological, behavioral (vigilance stages quantification) and thermo-physiological approaches. The rats were exposed 24 hours to a 2.45 GHz pulsed electromagnetic field at low power density. In this exposure conditions, no significant effect have been reported. (authors)

Energy Technology Data Exchange (ETDEWEB)

This paper reports on pumped storage plants which have become an effective way for some utility companies that derive power from hydroelectric facilities to economically store baseload energy during off-peak hours for use during peak hourly demands. According to the Electric Power Research Institute (EPRI) in Palo Alto, Calif., 36 of these plants provide approximately 20 gigawatts, or about 3 percent of U.S. generating capacity. During peak-demand periods, utilities are often stretched beyond their capacity to provide power and must therefore purchase it from neighboring utilities. Building new baseload power plants, typically nuclear or coal-fired facilities that run 24 hours per day seven days a week, is expensive, about $1500 per kilowatt, according to Robert Schainker, program manager for energy storage at the EPRI. Schainker the that building peaking plants at $400 per kilowatt, which run a few hours a day on gas or oil fuel, is less ...

International Nuclear Information System (INIS)

Platelet deposition on bovine pericardial-tissue mitral-valve prostheses in 11 dogs was observed noninvasively by use of "1"1"1In-labeled platelets and quantified after sacrifice at one (n . 3), 14 (n . 3), and 30 (n . 5) days postimplantation (300-400 microCi of labeled platelets having been injected 24 hours previously). Thrombosis on the sewing ring and pericardial leaflets at one and 14 days and on the leaflets at 30 days was delineated in scintiphotos. In vitro quantification (% injected dose) indicated that the leaflets, sewing ring, and perivalvular tissue retained 0.904% of labeled platelets at one day postimplantation, 0.198% at 14 days, and 0.040% at 30 days. Platelet half-life was reduced to 38 hours at 21 days postimplantation but returned toward the normal (50 hours) with fibrous ingrowth in the sewing ring. Microembolism in lung and kidney, as measured by tissue/blood radioactivity ratio, also was decreased significantly at 30 ...

International Nuclear Information System (INIS)

Thirty-four patients with prostatic carcinoma were studied with quantitative bone scintigraphy and whole-body counting (WBC) 1 and 24 h after injection of "9"9"mTc-MDP before as well as two weeks and two months after orchiectomy. Thirteen of the patients had normal bone scintigrams and WBR at the three different investigations; 21 had skeletal metastases. The latter showed throughout the study higher local gamma camera count rates as well as WBR values than the patiens with normal scintigrams. In these patients a ''flare phenomenon'', with an increase in count rate two weeks after orchiectomy followed by a decrease two months post-operatively, was seen with quantitative bone scintigraphy but not with WBC. However, WBC may be a valuable method indicating the total extent of skeletal metastases in the body, while quantitative bone scintigraphy is more accurate in the interpretation of individual skeletal metastases. (orig.).

International Nuclear Information System (INIS)

In the present study a partial replacement of aggregate with two different ratios of waste rubber (5%, 10%) with the addition of a constant ratio of rice husk ash (RHA), 5% was carried out. The hardened cement mortar used the optimum water of consistency. The specimens were molded into 1 inch cubic moulds .The specimens were first cured for 24 hours, at 100% relative humidity and then cured under tap water for 3, 7 and 28 days followed by irradiation at different doses of gamma irradiation namely 5 and 10 kGy. The physico-chemical and mechanical properties such as compressive strength, total porosity and bulk density were studied for the three types of specimens. The results showed that the values of the compressive strength, bulk density and chemically combined water of the blended cement mortar paste (OPC-RHA) increase ,while blended cement mortar paste with 5% RHA and 5, 10% waste rubber decrease. The results were confirmed by scanning ...

Energy Technology Data Exchange (ETDEWEB)

Iofetamine HCI {sup 123}I is the generic name for the hydrochloride salt of N-isopropyl-p-iodoamphetamine labeled with {sup 123}I, commonly called IMP. Iofetamine HCI {sup 123}I is prepared by isotopic exchange with [{sup 123}I]Nal and is formulated in isotonic aqueous NaCl solution containing 1 mCi/ml iofetamine HCI I 123, 0.15 mg/ml iofetamine HCI carrier, and phosphate buffer for pH control. The radiochemical purity is >97%, and the product is stable for more than 24 hours; the commercial product distributed today is prepared with high purity {sup 123}I with >98% radionuclidic purity. Two radioiodinated agents have seen significant clinical application for functional brain imaging: iofetamine HCI (IMP) (1) and N,N,N{prime}-trimethyl-N{prime}-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine HIPDM (2). lofetamine HCI {sup 123}I is commercially available in the United States, Europe, and Japan. Although their primary use is for ...

International Nuclear Information System (INIS)

Dynamic fracture toughness tests were performed on materials which had been subjected to one of three long-time post weld type stress relief heat treatments: 48 hours at 1000/degree/F (538/degree/C), 24 hours at 1125/degree/F (607/degree/C), and 48 hours at 1125/degree/F (607/degree/C). Linear elastic K/sub Id/ results were obtained at low temperatures while J-integral techniques were utilized to evaluate dynamic fracture toughness over the transition and upper shelf temperature ranges. Tensile, Charpy impact, and drop weight nil-ductility transition tests as well as room temperature, air environment fatigue crack growth rate tests (SA508 Cl 2a only) were also performed. The fracture toughness of both materials exceeded the ASME specified minimum reference toughness K/sub IR/ curve. 17 refs.

International Nuclear Information System (INIS)

The specific receptor sites and the endocytosis of transferrin (Tf) are evidenced in a cell line (HT-29) derived from a human colic adenocarcinoma by means of "1"2"5I radiolabeled Tf. The receptor density is studied in undifferentiated (UD) or differentiated (D) cells with respective doubling times of about 24 hours and 46 hours. The number of binding sites for Tf is 162,000 (K_d = 7.8 nmol/l in ND cells and 68,000 (K_d = 7.40 nmol/l) in D cells. The distribution between the Tf bound to the cell surface and the internalized Tf is investigated by elimination of Tf bound to the surface by an acid wash method. The intracellular cycle of Tf seems to be characterized by a slower kinetics in UD cells. The high density of Tf receptor sites in HT-29 UD cells should allow the detection or the treatment of highly evolutive colic adenocarcinoma by means of Tf.

International Nuclear Information System (INIS)

Thirty-six patients with acquired immunodeficiency syndrome (AIDS), who were febrile but without localizing signs, underwent indium-111 leukocyte scintigraphy 24 hours after injection of labeled white blood cells (WBCs) and were restudied 48 hours after injection of gallium-67 citrate. Fifty-six abnormalities were identified as possible sources of the fever; 27 were confirmed with biopsy. Of these 27, 15 were identified only on In-111 WBC scans (including colitis, sinusitis, and focal bacterial pneumonia); six, only on Ga-67 scans (predominantly Pneumocystis carinii pneumonia and lymphadenopathy); and six, on both studies (predominantly pulmonary lesions). In-111 WBC scanning revealed 21 of 27 abnormalities (78%) and gallium scanning, 12 of 27 (44%). If only one scintigraphic study has been performed, particularly with Ga-67, a significant number of lesions would not have been detected. The authors believe radionuclide evaluation of the febrile ...

International Nuclear Information System (INIS)

We studied the dose-response effects of #gamma#-irradiation on the weight gains of the body and the brain in ICR mice exposed to various doses of "6"0Co #gamma#-irradiation ranging from 0 to 1.5 Gy on day 13 of pregnancy (E13). We found that 0.5 Gy #gamma#-irradiation caused a significant reduction in brain weight but not in body weight among 6-week-old mice. Higher doses (1.0, 1.5 Gy) seriously inhibited body and brain development, resulting in significantly low weights at 6 weeks of age. A significantly lower brain weight among fetuses exposed to 1.5 Gy was found as early as 24 hours after exposure, while significant reductions in the body weight of these same fetuses appeared 3 days after exposure. The effects of radiation on brain and body development were similar for both males and females. (author).

International Nuclear Information System (INIS)

Quantitative bone scintigraphy was performed at 4 and 24 h after injection of "9"9"mTc-MDP. The lower thoracic and all the lumbar vertebrae were recorded in 37 patients with prostatic carcinoma before orchiectomy as well as two weeks, two and six months postoperatively. Fourteen patients had normal bone scintigrams. By means of the measured variation in the count rate between normal vertebrae, the criterion for a vertebra to be considered as abnormal was determined using the 4 h-uptake values. For patients with normal scintigrams the count rate at 24 h was below the 4 h level and the mean 24 h/4 h ratio was determined to be 0.85 #+-# 0.09 (1 SD). Normal vertebrae in patients with skeletal metastases had only slightly lower count rate values at 24 h than at 4 h. Abnormal vertebrae showed a higher count rate at 24 h, especially two weeks postoperatively, while a tendency towards lower values than at 4 h was seen after 6 months. If the 24 h/4 h ratio is used as an extra criterion to the ...

Energy Technology Data Exchange (ETDEWEB)

The regional concentrations of nine radiochemicals were measured in rat brain after induction of cerebral ischemia to identify tracers concentrated by brain undergoing selective neuronal necrosis. Transient (30 minute) forebrain ischemia was produced in the rat; 24 hours after cerebral recirculation the radiochemicals were injected intravenously and allowed to circulate for 5 hours. The brain concentrations of the radiochemicals in dissected regions were determined by scintillation counting. Forebrain ischemia of this nature will produce extensive injury to striatal neurons but will spare the great majority of neocortical neurons at 24 hours. The regional concentrations of these radiochemicals varied considerably in both control and ischemic animals. In postischemic animals, 4 radionuclides (/sup 63/Ni, /sup 99/TcO/sub 4/, /sup 22/Na, and (/sup 3/H)tetracycline) were concentrated in the irreversibly ...

International Nuclear Information System (INIS)

It has been previously stated that the minimum physiological recommendations for the indispensable amino acids in health adults, as proposed by FAO/WHO/UNU in 1985, are far too low, except for the methionine. An amino acid stable isotopic kinetic study was conducted to seek further experimental support to this hypothesis. Twenty healthy young men received an l-amino acid based diet, supplying 140 mg N.kg"-"1.d"-"1, patterned on egg protein for 1 week, then for 3 weeks either i) a pattern based on current international recommendations (FAO diet, n=7), ii) a the tentative Laboratory of Human Nutrition of the Massachusetts Institute of Technology, new amino acid recommendation pattern (MIT diet, n=7) or iii) again the egg hen pattern (EGG diet, n=6). All subjects were again studied for one final, consecutive week of the egg diet. At the end of the initial week, at the first and third week with the three experimental diets,and after three days following the return of the egg diet, an 8 h ...

Science.gov (United States)

The adipocytokine adiponectin is released by adipocytes upon activation of the peroxisome proliferator-activated receptor gamma (PPAR gamma). PPAR gamma has binding sites for thiazolidinediones and free fatty acids (FFAs). To evaluate if adiponectin serum concentrations are synergistically regulated by FFAs and thiazolidinediones IN VIVO plasma FFAs were acutely elevated in healthy subjects pre-treated with rosiglitazone or placebo. Sixteen healthy male subjects (23-37 years) were included in this double-blind, randomized, placebo-controlled parallel-group study. Rosiglitazone 8 mg or placebo was administered daily for 21 days. On the last day plasma FFA concentrations were increased by an intravenous triglyceride/heparin infusion. Blood for determination of adiponectin, C-reactive protein (CRP), leptin, resistin, FFAs, glucose, and insulin was drawn at baseline and on day 21 before and after 5 hours of triglyceride/heparin infusion. ...

British Library Electronic Table of Contents (United Kingdom)

Ethnopharmacological relevance: Extracts of the roots of Scutellaria baicalensis Georgi (Labiatae) have been widely used to relieve fever related to bacterial infection and inflammatory diseases in traditional Korean medicine and have been reported to be effective in brain diseases. These experiments were conducted to examine the effects of oral administration of Scutellaria baicalensis extracts on the rescue of memory impairments induced by chronic cerebral hypoperfusion or chronic lipopolysaccharide (LPS) infusion. In addition, the underlying mechanisms of these effects were investigated. Materials and methods: In the first experiment, chronic cerebral hypoperfusion was induced in male Wister rats by bilateral common carotid artery occlusion (BCCAo). Daily administration of Scutellaria b...

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Caffeine and related xanthines were identified as potent stimulators for the bacterial cellulose production in A. xylinum. These compounds are present in several plants whose infusions are useful as culture-medium supplements for this acetobacterium. The proposed target for these native purine-like inhibitory substances is the novel diguanyl nucleotide phosphodiesterase(s) that participates in the bacterial cellulogenic complex.

UK PubMed Central (United Kingdom)

The substantia nigra pars reticulata (SNR) controls seizures in a sex-specific manner. At postnatal day 15 (P15), SNR infusion of GABA_A receptor agonist muscimol have proconvulsant...Full Text Available

International Nuclear Information System (INIS)

To determine the efficacy and safety of Total Dose Infusion (TDI) of low molecular weight iron dextran for the treatment of iron deficiency anemia compared to oral iron replacement during pregnancy through improvement in hemoglobin (Hb) after intervention. Non-randomized control trial. A group of 100 pregnant women with gestational age greater than 12 weeks with confirmed diagnosis of iron deficiency anemia attending the antenatal clinics were enrolled in this study. Total dose iron infusion of low molecular iron dextran was given to these patients after calculating iron deficit, in a monitored in-patient setting. Control comprised of a second group of 50 pregnant females matched for age, parity and baseline hemoglobin, tolerant to oral iron supplementation (ferrous sulphate 200 mg three times a day) attending the antenatal clinics during the same period. Post-treatment hemoglobin levels of study group as well as the oral control group were ...

International Nuclear Information System (INIS)

Six commercial insecticides viz., decis 25EC (deltamethrin), thiodan 35EC (endosulfan), curacron 500EC (profenophos), somialfa 110EC (esfenvalerate), denitol 30EC (fenpropathrin) and advantage 20EC (carbosulfan) were tested with recommended doses against first instar larvae of cotton bollworm, Helicoverpa armigera (Hub.) to determine their degree of toxicity under controlled laboratory conditions. Leaf dip method was applied for these tests. Insect mortality was assessed after 24, 48 and 72 hours of insecticide application. Results showed that curacron 500EC gave significantly high mortality of 100 % after 24 hours of application followed by thiodan 35EC, somialfa 110EC and advantage 20EC causing 93, 80 and 72 % mortality, respectively. Whereas, denitol 30EC and decis 25EC showed the minimum, non-significant differences by giving mortality of 45 and 43 %, respectively. Effectiveness of all insecticides increased after 48 hours but their degree ...

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To assess the efficacy and resulting complications of tetracycline sclerotherapy in renal, hepatic, ovarian, and perivesical cysts. We retrospectively reviewed 23 cases of benign cysts (16 renal, 4 hepatic, 2 ovarian, and 1 perivesical) in 22 patients in whom the condition was diagnosed or confirmed by either ultrasound, CT, or cytology, and who underwent percutaneous tetracycline sclerotherapy. Using a 21-gauge Chiba needle, the target cyst was punctured under ultrasound guidance. Prior to the injection of 1500 mg of tetracycline diluted in 5 ml of normal saline, almost all the cystic content was aspirated, and at the end of the procedure the tetracycline was left in the cyst. During a period of between 3 and 22 months, 18 of the 23 cases were followed up. In six of the 18 cases followed up, the cysts either decreased in size by 10%, or collapsed completely. In seven cases a collapse of over 50% was noted, and in the remaining five the cyst recurred. In one of these, complete collapse ...

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A recent road test at LLNL underscored the zinc/air battery`s capacity to give electric vehicles some of the attractive features of gas-driven cars: a 400-km range between refueling, 10-minute refueling, and highway-safe acceleration. Developed at Lawrence Livermore National Laboratory, the battery weights only one-sixth as much as standard lead/acid batteries and occupies one-third the space, yet costs less per mile to operate. What`s more, because the battery is easily refuelable, it promises trouble-free, nearly 24-hour-a-day operation for numerous kinds of electric vehicles, from forklifts to delivery vans and possibly, one day, personal automobiles. The test of a Santa Barbara Municipal Transit bus with a hybrid of zinc/air and lead/acid batteries capped a short development period for the zinc/air battery. The test run indicated the zinc/air battery`s potential savings in vehicle weight from 5.7 to 4.0 metric tons, in battery weight from ...

International Nuclear Information System (INIS)

The development of the microstructure on aging of an (#alpha# + #beta#) type titanium alloy containing 6Al-1.6Zr-3.3Mo-0.3Si (VT9) (in weight percent) has been studied. The #beta#-transus temperature of this alloy is approximately 1243 K. Solution treatment in the #beta#-phase field of the alloy followed by quenching in water at room temperature resulted in the formation of a single-phase martensite structure. The martensitic structure was confirmed to be orthorhombic (#alpha# double-prime) using X-ray diffraction. The water-quenched (WQ) specimens were subjected to aging treatments at temperatures of 823, 873, and 973 K for various lengths of time. Aging at 823 K for times between 24 and 100 hours did not bring about any noticeable change in the microstructure. Aging at 823 K for 200 and 300 hours resulted in the heterogeneous precipitation of s_2 silicide particles and thin films of #beta# sandwiched between the interplatelet boundaries of martensite. Electron diffraction analysis ...

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Purpose: To evaluate MR imaging of the hip in patients with a clinically suspected impacted fracture of the femoral neck in cases where conventional plain films show negative or equivocal findings. Material and Methods: Twenty-seven such patients were prospectively examined by MR imaging with a 1.0 T unit, within 24 hours of admittance to hospital. A coronal T1-weighted turbo spin-echo sequence (n=27), and a coronal STIR sequence (n=25) or a coronal T2-weighted turbo spin-echo fast saturation sequence (n=2) were used. The evaluations were made by 2 radiologists with experience in musculoskeletal radiology. Results: There were 6 patients with a petrochanteric fracture, 2 without and 4 with slight displacement. Five patients had an impacted fracture of the femoral neck, and 3 had a fracture of the superior pubic bone. Of 2 patients with advanced arthrosis, i had an impacted femoral neck fracture and the other a nondisplaced intertrochanteric ...

International Nuclear Information System (INIS)

One rationale proposals to increase the efficiency of PDT is to combine photo-sensitization with other treatment modalities, including modulation of arachidonic acid metabolism. In combine treatment we examined the effects of 48 h and 24 h pre-treatment of cells with 5- lipoxygenase inhibitor MK-886 prior to photoactivation of hypericin on cell cycle distribution and DNA synthesis. All parameters were examined 24 hours after hypericin activation. Pre-treatment of HT-29 with 5-lipoxygenase inhibitor MK-886 followed by PDT resulted in most significant effects on cell cycle perturbations. Administration of MK-886 alone as well as combination of low doses MK-886 with hypericin induced S phase accumulation. Increasing of MK-886 concentration induced massive changes in the cell cycle progression. Pre-treatment of HT-29 cells with MK-886 alone (15 #mu#M; - 48 h) caused accumulation of cells in S-phase (58 % in S-phase and 36 % in G_0/G_1 phase). ...

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Patients with Ewing's sarcoma who present with a central axis or proximal extremity primary and/or with metastatic disease have a poor prognosis despite aggressive combination chemotherapy and local irradiation. In this high risk group of patients, total body irradiation (TBI) has been proposed as a systemic adjuvant. To aid in the design of a clinical TBI protocol, the authors have studied in the in vitro radiation response of two established cell lines of Ewing's sarcoma and human bone marrow CFUc. The Ewing's lines showed a larger D_0 and anti-n compared to the bone marrow CFU. No repair of potentially lethal radiation damage (PLDR) was found after 4.5 Gy in plateau phase Ewing's sarcoma cells. A theoretical split dose survival curve for both the Ewing's sarcoma lines and human bone marrow CFUc using this TBI schedule shows a significantly lower surviving fraction (10"-"4-10"-"5) for the bone marrow CFUc. Based on these in vitro results, two 4.0 Gy fractions separated by ...

Science.gov (United States)

The effects of felbamate on the pharmacokinetics of a low-dose combination oral contraceptive containing 30 micrograms ethinyl estradiol and 75 micrograms gestodene were assessed in a randomized, double-blind, placebo-controlled parallel-group study in healthy premenopausal female volunteers established in a regimen of oral contraceptive use. They received either placebo or 2400 mg/day felbamate from midcycle (day 15) to midcycle (day 14) of two consecutive oral contraceptive cycles (months 1 and 2). Pharmacokinetic assessments of ethinyl estradiol and gestodene were performed on day 14 of both cycles. To determine whether ovulation occurred, plasma progesterone and urinary luteinizing hormone levels were measured, and diaries recording vaginal bleeding were kept. Felbamate treatment resulted in a significant 42% decrease in gestodene area under the plasma concentration-time curve (0 to 24 hours) (p = 0.018) compared with baseline, whereas a ...

International Nuclear Information System (INIS)

Lysozyme, ethylenediaminetetracetic acid, chlorine, x-irradiation and microwaves were used in experimental attempts to eliminate Salmonella senftenberg 775W or Salmonella typhimurium from turkey drumsticks and whole carcasses. Turkey drumsticks or whole carcasses were artificially contaminated with S. senfenberg 775W or S. typhimurium in concentrations ranging between 5 x 10"5 to 8 x 10"5 viable cells per ml. of contaminating fluid. After each treatment, samples were cultured, plated, and tested according to standard methods to determine the susceptibility of Salmonella organisms to the particular treatment. A 0.1 percent solution of lysozyme eliminated the S. senftenberg 775W at 22"0C within three hours. A 0.5 percent solution of ethylenediaminetetracetic acid failed to destroy the test organism under the same conditions. Eighty thousand rads of X-ray eliminated the test organism on turkey drumsticks but failed to remove it from whole turkey carcasses. Microwaves eliminated the S. ...

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The energetic characteristics of 6 types of poplar clones cultivated for different pedoclimatic conditions in Romania were determined. Four clones were developed in Italy and 2 in Romania. Five experimental cultures were used to analyze the plant survival rate and biomass production rate. After 2 years of study, the Italian clones were found to have very good adaptability to the pedoclimatic conditions in Romania in comparison with local clones. The Italian clones Monviso and AF-6 registered the most substantial growths and the highest resistance to disease. Bioethanol was synthesized by acidic hydrolysis of the cellulose using 2 approaches. In the first approach the lignocellulosic raw material was hydrolyzed with diluted sulfuric acid at 50 degrees C for 24 hours. After filtration, the solid residue was treated with 30 per cent H{sub 2}SO{sub 4} at 100 degrees C for 6 hours. The resulting solutions were neutralized with Ca(OH){sub 2} ...

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The three main objectives of this study were: (1) to determine if depletion of proteoglycans from the cartilage matrix that occurs during osteoarthritis causes a measurable increase of cartilage proteoglycan components in the synovial fluid and sera, (2) to observe what effect intracellular cAMP has on the expression of matrix components by chondrocytes, and (3) to determine if freshly isolated chondrocytes contain detectable levels of mRNA for fibronectin. Canine serum keratan sulfate and hyaluronate were measured to determine if there was an elevation of these serum glycosaminoglycans in a canine model of osteoarthritis. A single intra-articular injection of chymopapain into a shoulder joint increased serum keratan sulfate 10 fold and hyaluronate less than 2 fold in 24 hours. Keratan sulfate concentrations in synovial fluids of dogs about one year old were unrelated to the presence of spontaneous cartilage degeneration in the joints. High ...

International Nuclear Information System (INIS)

The outcome was retrospectively examined and prognostic factors were discussed for arterial chemo-infusion therapy (ACT) through an implanted reservoir system and radiation therapy (RT) in patients with unresectable intrahepatic cholangiocarcinoma (CCC). ACT plus RT were conducted to 25 patients (mean age 61.7 y, M/F 12/13, stage III-IVB) during 10 years from 1996 to 2005 with various regimens of cisplatin (CDDP), 5- fluorouracil (FU), epirubicin (FARM), mitomycin C (MMC) plus 39-50 Gy of radiation in a fractionated manner partly involving internal RT (2 cases, 15 Gy) and RT for metastatic bone (1, 25 Gy). The survival rates at 1, 2 and 3 years after ACT+RT were respectively 52.5, 43.7 and 28.1%; total efficacy (PR) was 36% (9/25) at 6 months; and significantly good prognostic factors were found to be female and absence of metastasis remote and/or lymphatic around artery. Authors concluded that ACT+RT was a meaningful treatment for highly advanced non-respectable ...

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X-ray fluorescence (XRF) and total-reflection X-ray fluorescence (TXRF) techniques suited well for a multi-element determination of K, Ca, Mn, Fe, Cu, Zn, Rb, and Sr in some Syrian medicinal plant species. The accuracy and the precision of both techniques were verified by analyzing the Standard Reference Materials (SRM) peach-1547 and apple leaves-1515. A good agreement between the measured concentrations of the previously mentioned elements and the certified values were obtained with errors less than 10.7% for TXRF and 15.8% for XRF. The determination of Br was acceptable only by XRF with an error less than 24%. Furthermore, the XRF method showed a very good applicability for the determination of K, Ca, Mn, Fe, Cu, Zn, Rb, Sr, and Br in infusions of different Syrian medicinal plant species, namely anise (Anisum vulgare), licorice root (Glycyrrhiza glabra), and white wormwood (Artemisia herba-alba)

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An efficient method of hydrogen storage in nano-porous carbons is its reversible sorption by electrochemical decomposition of a KOH water solution according to the following equation: C + xH{sub 2}O + xe{sup -} {yields} (CH{sub x}) + xOH{sup -} where (CH{sub x}) stands for the hydrogen inserted into the nano-porous carbon during charging and oxidized during discharging. Although various carbon materials have been investigated as hydrogen adsorbents, the information about the storage mechanism as well as the nature of the hydrogen/carbon interaction is still not sufficient. In order to extend the understanding of the process, carbon samples charged electrochemically were investigated by temperature programmed desorption (TPD). The nature of the hydrogen/carbon interaction was studied by electrochemical analysis at different temperatures. The TPD experiments consist of heating the samples from room temperature to 950 C and of quantitative analysis by On-line mass spectrometry, the ...

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Full text: In 1995, we demonstrated the use of pretargetting three steps method and biotinylated tetracycline using radiolabelled {sup 99m}Tc-DTPA-biocytinamide for the detection of tumour cells in (C57B1/6 x BALB/C) F1 mice with E-3 thymoma. The three steps were (1) IP injection of biotinylated-tetracycline conjugate (1:1) ratio, (2) 96 hours later Avidin/Streptavidin was injected, and (3) 24 hours after (2), {sup 99m}Tc-biocytinamide -cDTPA was injected. Mice were sacrificed 16/24 h after (3) by cervical dislocation. Biodistribution of radioactivity tumour to blood, liver, bone were T:B1= 15.0, T:Li= 5.08, T:Bo=15.0. The percentage of injected dose per g was T= 3.15% and B1= 0.21%. To prolong circulation of Avidin and therefore its uptake into tumour, Avidin was covalently bound to polyethylene-glycol (PEG20 KD) at the molar ratio of PEG:Avidin 100:1 and 400:1. The pegulated Avidin was then cleared from the circulation using ...

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Purpose : To evaluate whether the early pulmonary irradiation can prevent or decrease the pulmonary damage and contribute to improve ultimate survival in paraquat lung. Materials and Methods : From Jun. 1987 to Aug. 1993, thirty patients with paraquat poisoning were evaluated. Fourteen of these patients were received pulmonary irradiation(RT). All of the patients ere managed with aggressive supportive treatment such as gastric lavage, forced diuresis, antioxidant agents and antifibrosis agents. Ingested amounts of paraquat were estimated into three groups(A: minimal < about 5cc, B: mouthful 5-50 cc, C: Large > 50cc). Pulmonary irradiation was started within 24 hours after admission(from day 1 to day 11 after ingestion of paraquat). Both whole lungs were irradiated with AP/PA parallel opposing fields using C0-60 teletherapy machine. A total of 10Gy(2Gy/fr. X 5 days)was delivered without correction of lung density. Results : In ...

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British Library Electronic Table of Contents (United Kingdom)

Patients with acute myocardial infarction (AMI) and diabetes mellitus, as well as patients admitted with elevated blood glucose without known diabetes, have impaired outcome. Therefore intensive glucose-lowering therapy with insulin (IGL) has been proposed in diabetic or hyperglycaemic patients and has been shown to improve survival and reduce incidence of adverse events. The current manuscript provides an overview of randomised controlled trials investigating the effect of IGL. Furthermore, systematic glucose?insulin?potassium infusion (GIK) has been studied to improve outcome after AMI. In spite of positive findings in some early studies, GIK did not show any beneficial effects in recent clinical trials and thus this concept has been abandoned. While IGL targeted to achieve normoglycaemi...

British Library Electronic Table of Contents (United Kingdom)

Much progress has been made in the clinical, biological and technical aspects of the T-cell-depleted haploidentical hematopoietic stem cell transplantation (HSCT). Our experience demonstrates that infusing a megadose of extensively T-cell-depleted hematopoietic peripheral blood stem cells after an immuno-myeloablative conditioning regimen in acute leukemia patients ensures sustained engraftment with minimal GvHD without the need of any post-transplant immunosuppressive treatment. Since our first successful pilot study, our efforts have concentrated on developing new conditioning regimens, optimizing the graft processing and improving the post-transplant immunological recovery. The results we have so far achieved in high risk acute leukemia patients show that haploidentical transplantation ...

Science.gov (United States)

Effective localization of small magnets against a noisy, real world background can involve various methods to first identify the magnetic fields produced by the magnet of interest, then to filter out background noise, and then to analyze the available magnetic field data to localize the magnet. Here we discuss low cost techniques which allow localization of small magnets with field strengths in the milliGauss range against real world background fields in the range of hundreds of mG, which may be fluctuating by up to tens of mG. Such techniques allow magnet tracking to be used to localize catheters in place of more invasive and expensive methods, e.g. fluoroscopy, for a variety of applications, including drug infusion with peripherally inserted central catheters (PICCs), laser ablation (TMR, PTMR) and introduction of pacemaker leads.

British Library Electronic Table of Contents (United Kingdom)

Currently, human leukocyte antigen (HLA)-mismatched/haploidentical allografts have been validated as an alternative stem cell source for patients who have no immediate access to an HLA-matched related or unrelated donor. However, relapse remains a challenge after HLA-mismatched/haploidentical hematopoietic stem cell transplantation (HSCT) that is employed in the treatment of patients with hematological malignancies. In recent years, newly developed immunomodulatory strategies, which include prophylactic and therapeutic donor lymphocyte/natural killer (NK) cell infusion, donor selection based on NK alloreactivity/non-inherited maternal antigen (NIMA), immune reconstitution promotion, and application of exogenous cytokines, have made it possible to decrease the relapse rate and improve outco...

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Delayed Afterdepolarization in Sinoatrial Node. Introduction: Recent evidence indicates that spontaneous sarcoplasmic reticulum Ca release and Na-Ca exchanger current activation contribute to the sinoatrial node (SAN) automaticity. These findings suggest that SAN activity may share mechanisms that underlie both automaticity and triggered activity. The aim of this study is to test the hypothesis that spontaneous, nonvoltage gated, intracellular Ca (Cai) elevation may induce delayed afterdepolarization (DAD) in intact SAN during isoproterenol infusion. Methods and Results: We simultaneously mapped Cai and membrane potential in 31 isolated Langendorff-perfused canine right atriums (RA). Isoproterenol increased heart rate and late diastolic Cai elevation (LDCAE) of the superior SAN, leading to...

International Nuclear Information System (INIS)

Intra-arterial subtraction angiography(IADSA) using Fuji computed radiography(FCR) was performed on 130 patients with cervical, pelvic, peripheral and abdominal diseases. It was compared with conventional angiography(radiographs produced by combining photographic film with an intensifying screen) performed on same patients. Radiographs produced by FCR were better than conventional radiographs in cervical, pelvic and peripheral angiography. In the abdominal angiography using FCR, there was misregistration artifact in some cases, but in hepatic angiography, the new radiographs under the injection of small amount of contrast medium(about 10ml) and the short exposure duration(about 10 seconds) were excellent. It was as valuable as conventional angiography (infusion hepatic angiography) for diagnosing hepatic neoplasms. (author).

UK PubMed Central (United Kingdom)

Continuing Medical Education (CME) is a requirement among practicing physicians to promote continuous enhancement of clinical knowledge to reflect new developments in medical care. Previous research...Full Text Available

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Purpose: To report on the nephron-sparing, percutaneous ablation of a large renal cell carcinoma by combined superselective embolization and percutaneous radiofrequency ablation. Materials and Methods: A 5 cm renal cell carcinoma of a 43-year-old drug abusing male with serologically proven HIV, hepatitis B and C infection, who refused surgery, was superselectively embolized using microspheres (size: 500 - 700 {mu}m) and a platinum coil under local anesthesia. Percutaneous radiofrequency ablation using a 7F LeVeen probe (size of expanded probe tip: 40 mm) and a 200 Watt generator was performed one day after transcatheter embolization under general anesthesia. Results: The combined treatment resulted in complete destruction of the tumor without relevant damage of the surrounding healthy renal tissue. The patient was discharged 24 hours after RF ablation. No complications like urinary leaks or fistulas were observed and follow up CT one day and 4 ...

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A prospective pilot trial was performed in 20 patients randomised to receive either {sup 131}I-Lipiodol therapy alone (n=10) or {sup 131}I-Lipiodol combined with a short low-dose cisplatin infusion (n=10), the aim being to evaluate the possible positive influence of a radiosensitiser on toxicity and tumour response. An activity of 1,354-2,128 MBq (mean 1,824 MBq) [36.6-57.5 mCi (mean 49.3 mCi)] {sup 131}I-labelled Lipiodol was administered by selective instillation in the hepatic artery. Cisplatin was given in a dose of 30 mg/m{sup 2} at day -1 and day +6 (day 0: {sup 131}I-Lipiodol). The primary endpoint of this trial was toxicity of therapy; points of secondary interest were tumour response and survival at 6 months. With the use of cisplatin we found a higher percentage of stable or diminished tumour size (90%, vs 40% without). A benefit in group survival at 6 months was not evident. Low-grade stomatitis in one patient and minor changes in peripheral blood count ...

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The lymphographic agent Lipiodol (iodized oil) has been found to localize and remain in tumor vessels. Based on this finding, we attempted transcatheter internal radiotherapy by radioactive iodized oil (I-131 tagged Lipiodol) prepared by isotopic exchange reaction. Transcatheter internal radiotherapy (TCIR) was attempted in twelve patients with inoperable hepatoma by infusing a therapeutic dose of I-131 Lipiodol (7.6 approx. 28.3 mCi/2.0 approx. 5.0 ml) via the hepatic artery. Serial changes of serum alpha-fetoprotein (AFP) levels and in the size of tumor on computed tomography (CT) were estimated to evaluate the therapeutic effect. Serum AFP levels decreased in 9 patients with initial elevated levels of serum AFP, although they were again elevated in three of them within four weeks. More than 50 % decrease in tumor size was observed in 6 patients (50 %). There were no serious complications. This preliminary results suggest that TCIR with I-131 Lipiodol will be one ...

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The adverse effects and diagnostic accuracy of thallium-201 myocardial SPECT after intravenous infusion of adenosine triphosphate (ATP) were studied and compared with SPECT examinations with other type of loading. The subjects of the study were 147 patients with or without coronary artery disease, who underwent some type of loading SPECT and coronary arteriography (CAG) within 30 days. Myocardial ischemia was evaluated qualitatively in SPECT and was compared with CAG for the diagnostic accuracy of coronary artery disease. The degree of myocardial uptake defect was also calculated semiquantitatively using visual scoring method and compared with coronary artery severity score. The adverse effects occurred in 46.7% of ATP loading SPECT which was more frequent that DIP loading SPECT, but all of them were transient and mild. As for the diagnostic ability the ATP loading SPECT was as effective as other type of loading in qualitative interpretation, and the perfusion ...

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The subfornical organ is a major receptor area for one of the principal stimuli of thirst, the octapeptide, angiotensin II. In conscious water-sated rats, the authors examined the effects of intravenous infusion of angiotensin II on the rate of glucose utilization in the subfornical organ and in structures anatomically and functionally connected with it. Angiotensin II produced pressor and drinking responses and increased glucose utilization selectively in the subfornical organ and pituitary neural lobe and in no other brain structure. Treatment with the angiotensin II antagonist, sar1-leu8-angiotensin II, before intravenous administration of angiotensin II prevented metabolic stimulation of the subfornical organ and neural lobe. Captopril, an inhibitor of angiotensin-converting enzyme, reduced subfornical organ glucose metabolism to a level similar to that found in control animals. These results demonstrate that peripheral angiotensin II stimulates glucose ...

British Library Electronic Table of Contents (United Kingdom)

Background: The outcome of acute myocardial infarction (AMI) complicated with cardiogenic shock is poor. The aim of this study was to analyse, whether upfront abciximab administration could improve the outcomes of cardiogenic shock. Methods: This multicentre open trial randomized 80 patients with AMI complicated by cardiogenic shock expected to undergo primary PCI into group A (routine upfront-pre-procedural-abciximab bolus followed by 12-h abciximab infusion) and group B (standard therapy). The study primary objective was 30-day combined outcome (death/reinfarction/stroke/new severe renal failure). Results: PCI was technically successful in 90% (A) versus 87.5% (B) patients. Abciximab was used in 100% (A) versus 35% (B). The primary endpoint occurred in 17 group A patients (42.5%) and 11 ...

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We investigated a method of analyzing the hemodynamics of the lung mass by contrast enhanced dynamic computed tomography (dynamic CT) to determine the difference in vascular supply between the pulmonary artery and bronchial artery using an experimental model. Our experimental model consisted of two injectors connected to two tubes, representing the pulmonary artery and bronchial artery, which were further connected to a chamber representing the lung mass. Following infusion of contrast medium into each tube with some delay time, dynamic CT scans were performed to obtain time density curves of the two tubes and the chamber. Using the time-density curve of contrast passage, flow rates from the two tubes into the chamber were calculated by the curve fitting method. Calculated values correlated well with the adopted flow rates of fluid from the injectors (r=0.893) in the experiment. The results indicate our method of individually measuring flow rates of dual-input ...

International Nuclear Information System (INIS)

There is increasing use of radiofrequency radiation (RFR) in industry for communications, welding, security, radio, medicine, navigation etc. It has been recognised for some years that RFR may interact with cardiac pacemakers and steps have been taken to prevent this interference. It is less well recognised that other metallic implants may also act as antennas in an RFR field and possibly cause adverse health effects by heating local tissues. There are a large and increasing number of implants having metal components which may be found in RFR workers. These implants include artificial joints, rods and plates used in orthopaedics, rings in heart valves, wires in sutures, bionic ears, subcutaneous infusion systems and (external) transdermal drug delivery patches"1. The physician concerned with job placement of such persons requires information on the likelihood of an implant interacting with RFR so as to impair health. The following outlines the approach developed in ...

British Library Electronic Table of Contents (United Kingdom)

Introduction: We have evaluated the ability of a semi-automated, optomotor reflex method to assess drug-induced visual dysfunction, in albino and pigmented rats and mice. Methods: Male Han Wistar (HW) and Long Evans (LE) rats and mice (CD-1 and C57BL/6) were tested in a chamber formed by 4 computer monitors displaying a rotating vertical grating, to elicit head-tracking movements. The highest visible grating frequency was taken as the threshold of visual acuity, in cycles per degree (c/d). Animals received an intravenous infusion of either sodium iodate (50mg/kg) or 0.9% w/v NaCl (aq). They were tested 2h later, then re-tested daily for a further 3days. The time course of the effect was assessed in HW rats over a 6-week period, including electron microscopy, and immunohistochemical analysi...

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The magnitude of Russian foreign debt, both official bilateral and commercial, compounded by collapse of the Russian economic system, is an obstacle in preventing the Russian Federation from effectively increasing the domestic priority of drawing down its nuclear weapons complex and providing a healthy, competitive environment to its nuclear cities. Debt-for-nature swaps, introduced in the early 1980s, provide debtor nations with a means of converting a portion of foreign debt into local currency, often at steep discounts, to use for purposes such as environmental protection that serve both a domestic and international need. This paper presents the debt-for-nature concept as a model for providing an infusion of funds to further U.S. and international nonproliferation objectives to help stabilize Russian closed city economic conditions through direct work on proliferation problems and remediation of the environment. A specific proposal is presented to demonstrate ...

Science.gov (United States)

... verges of a two-lane highway in continuous Jarrah Eucalyptus marginata forest of south-western Australia. Midway during this ... Birds were recorded from the beginning of continuous Jarrah Eucalyptus marg...

UK PubMed Central (United Kingdom)

An antiserum was raised in a rabbit against highly purified human liver dihydropteridine reductase (EC 1.6.99.7). Dihydropteridine reductase from human liver, in human cultured fibroblasts and in continuous...Full Text Available

UK PubMed Central (United Kingdom)

Purpose:The risks and benefits of continuing bisphosphonate therapy beyond 5 years in patients with primary osteoporosis have not been well established.Methods:We...Full Text Available

UK PubMed Central (United Kingdom)

Growth at increasing continuous irradiance (at high nutrient nitrate) and nutrient nitrate concentrations (at high continuous irradiance) furnished increases in the in vivo and in...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundWe examined whether older adults who had continuity of care with a primary care physician (PCP) had lower mortality.MethodsSecondary analyses...Full Text Available

UK PubMed Central (United Kingdom)

Premature circuit clotting is a major problem in daily practice of continuous renal replacement therapy (CRRT), increasing blood loss, workload, and costs. Early clotting is related to bioincompatibility,...Full Text Available

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... of species extinctions in around the world if global warming continues unabated, according to a new study published ... ...

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... increasing photorealism. Furthermore, developments in audio technology continue to increase the spatial awareness of users in VEs. ...

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... order probabilistic modelling, multisensor monitoring of ... object recognition, image registration and point ... of the Berkeley Continuous Media Toolkit. ...

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Results of tests on the 1 kg/h continuous reactor for the hydroliquefaction of coal are described. The reactor was operated at 415-435 C and 21 MPa using a continuous stirred reactor with a retention time of about 2 hours. All product oils were recovered by distillation. Sub-bituminous coal was found to give the best product yield. Tests using 5% red mud and 3% improved red mud showed significant increases in oil yield. (4 refs.)

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The purpose of this DOE-funded effort is to develop continuous processes for solvent extraction of coal for the production of carbon products. These carbon products include materials used in metals smelting, especially in the aluminum and steel industries, as well as porous carbon structural material referred to as ''carbon foam'' and carbon fibers. During this reporting period, efforts have focused on the facility modifications for continuous hydrotreating, as well as developing improved protocols for producing synthetic pitches.

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Mixed microstructures have been studied in low- carbon microalloyed steels suitable for automotive applications, after continuous cooling from the hot-rolled condition. Microstructural features such as polygonal ferrite, bainitic and acicular ferrite and microphase constituent are identified using transmission electron microscopy. The influence of these mixed structures on the tensile strength, impact toughness and fracture behaviour is examined. It is found that improvements in impact toughness as compared with microalloyed medium- carbon ferrite/pearlite steels can be achieved from these predominantly acicular structures developed by controlling alloy composition and continuous cooling of these lower carbon steels. (orig.).

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In this talk, we explore the feasibility of quantum computation using continuous-variable systems by means of local measurements only. In the first part of the talk, we will identify crucial limitations that arise when starting from Gaussian cluster states. This is done by resorting to a Gaussian projected entangled pair picture as well as to notions of continuous-variable quantum repeater networks. In the second part, we look at instances in which these limitations can be overcome, and how suitable encodings of qubits in oscillators and feasible non-Gaussian resource states give rise to universal schemes for quantum computing.

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The authors have shown previously that the domain recognizing receptors on activated human platelets is located on the human fibrinogen {gamma} chain between residues 400 and 411. To study the correlation between the structure of this segment of the {gamma} chain and its reactivity toward receptors on ADP-activated human platelets, they designed a series of analogues containing replacements at 9 out of 12 positions. A double substitution of the normal His{sup 400}-His{sup 401} sequence by Ala-Ala reduced the inhibitory potency of the dodecapeptide 3-fold. When Lys{sup 406} was replaced by Arg, the inhibitory potency of the dodecapeptide decreased 15 times. On the other hand, substitution of Ala{sup 408} with Arg increased the inhibitory potency of the dodecapeptide 6-fold. A drastic decrease in the reactivity of the dodecapeptide toward platelet receptors was observed when Val{sup 411} was replaced by leucine or cysteine or tyrosine. A 3-fold decrease in reactivity was noted when ...

International Nuclear Information System (INIS)

Twenty-four high-risk Ewing's sarcoma patients were treated on an intensive combined modality protocol including low-dose fractionated total body irradiaiton (TBI) and autologous bone marrow infusion (ABMI). Twenty patients (83%) achieved a complete clinical response to the primary and/or metastatic sites following induction therapy. The median disease-free interval was 18 months, and nine patients remain disease-free with a follow-up of 22 to 72 months. Local failure as a manifestation of initial relapse occurred in only three patients (15%), each having synchronous distant failure. Eight patients failed initially with only distant metastases, usually within 1-2 years following a complete clinical response. Two patterns of granulocyte recovery following consolidative therapy (including TBI and ABMI) were recognized. The time to platelet recovery was different for the groups with early and late granulocyte recovery. Patients with late recovery did not tolerate ...

International Nuclear Information System (INIS)

Coiling or infusion of embolic materials into a wide necked aneurysm can be performed with stenting. The purpose of our study is to assess the technical feasibility of aneurysm treatment with glue embolization after stenting. We used four Wallstents for surgically repairing eight canine carotid aneurysms. After confirmation of the aneurysms on the angiogram, we introduced a 6-7 F guiding catheter in order to deploy the stents. After stenting, we passed a microcatheter into the aneurysm lumen through the stent mesh. 28% glue was slowly injected until the glue cast completely filled the lumen. We evaluated the passage of a microcatheter through the stent meshwork, formation of the glue cast and the stents' ability to protection for any leakage of glue. The follow-up angiogram was obtained for two dogs, one to three times until 8 weeks, and then we sacrificed the dogs and performed pathologic examinations. Stenting was successful in all cases except one in which the ...

International Nuclear Information System (INIS)

To accomplish the environmental radiological surveillance need of India's ambitious nuclear power programme, Health Physics Division is infusing new technologies and improved analytical techniques for day to day measurements of various radionuclides in different environmental matrices. It is essential to have techniques for measuring the concentration of radionuclides just above the background level since the discharges from the nuclear facilities are very low i.e. in the range of 5-10% of the prescribed discharge limits by the regulatory bodies. In view of developing ultra-sensitive techniques, the aim of ongoing programmes of the division is to meet the challenges of measuring ultra trace level of radioactivity by adopting state of art new instrumentation and improved sample processing techniques. This will allow us to measure the lowest level of radioactivity (3H, 90Sr, 137Cs, 239+240Pu, etc.) in the environment and thereby estimating the lowest doses to the ...

UK PubMed Central (United Kingdom)

INTRODUCTION:Postprandial lipemia is characterized by an increased concentration of circulating lipids after fat intake and is an independent risk factor for cardiovascular disease....Full Text Available

UK PubMed Central (United Kingdom)

Summary of recent advancesSince their first description more than twenty years ago, Escherichia coli and Klebsiella pneumoniae possessing extended-spectrum...Full Text Available

UK PubMed Central (United Kingdom)

Streptococcus agalactiae continues to be a major cause of subclinical mastitis in dairy cattle and a source of economic loss for the industry. Veterinarians are often asked to provide information on...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

A novel continuous laminar shear structuring crystallizer with a suitable cooling system was designed and built. This is a new method to continuously crystallize edible fat in the desirable polymorphic form from the melt while being uniformly sheared.The machine consists of four main sections: Feed unit, shearing mechanism, cooling system and power unit. In each of these sections specific design considerations are taken into account which makes the process controllable and continuous. The shearing unit is made of two concentric cylinders. The internal cylinder is stationary and has a cooling system inside for temperature control. The outer cylinder rotates to produce a uniform shear in the sample fluid placed in the 1.5mm gap between the cylinders. The sample's feed rate is controlled whil...

Science.gov (United States)

A method for calculating flow through an airfoil cascade drawn on a surface of revolution is discussed. The three-dimensional flow was assumed to be represented by part-channels of varying width. The basic equations are the equation of continuity and the ...

UK PubMed Central (United Kingdom)

Like few other organs, the skin is continuously exposed to multiple exogenous and endogenous stressors. Superimposed on this is the impact of psychological stress on skin physiology and pathology....Full Text Available

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... C-3 ____ Page 21. NALIC-75189-30 Other Publications (Continued) NAVAIRINST 6260.1 -Chlorinated Solvents Instructions; for use of ...

UK PubMed Central (United Kingdom)

Because resistance to new insecticides may develop rapidly and cross resistance is often encountered, even between insecticides of different classes, there is a continual demand for the development...Full Text Available

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... XVIII Airborne Corps forces grew from one brigade of the 82nd Airborne Division to a multi-national organization of five full divisions (Eastern Area ...

UK PubMed Central (United Kingdom)

Aesthetic dentistry continues to evolve through innovations in bonding agents, restorative materials, and conservative preparation techniques. The use of direct composite restoration in posterior teeth...Full Text Available

Science.gov (United States)

CHORS, SDSU. OCRT Meeting (Washington, D.C., 14-16 Apr 2004). HPLC Phytoplankton Pigment Measurements: Continuation of Climate Quality Data Records ...

Science.gov (United States)

A new approach of gear fault diagnosis based on continuous wavelet transform is presented. Continuous wavelet transform can provide a finer scale resolution than orthogonal wavelet transform. It is more suitable for extracting mechanical fault information. In this paper, the concept of time-averaged wavelet spectrum (TAWS) based on Morlet continuous wavelet transform is proposed. Two fault diagnosis methods named spectrum comparison method (SCM) and feature energy method (FEM) based on TAWS are established. The results of the application to gearbox gear fault diagnosis show that TAWS can effectively extract gear fault information. The feature energy of the TAWS features the gear fault advancement very well and is conically proportional to the gear fault advancement.

British Library Electronic Table of Contents (United Kingdom)

Coupled continuous time random walks (CTRWs) model normal and anomalous diffusion of random walkers by taking the sum of random jump lengths dependent on the random waiting times immediately preceding each jump. They are used to simulate diffusion-like processes in econophysics such as stock market fluctuations, where jumps represent financial market microstructure like log returns. In this and many other applications, the magnitude of the largest observations (e.g. a stock market crash) is of considerable importance in quantifying risk. We use a stochastic process called a coupled continuous time random maxima (CTRM) to determine the density governing the maximum jump length of a particle undergoing a CTRW. CTRM are similar to continuous time random walks but track maxima instead of sums....

Science.gov (United States)

Feb 23, 2011 ... The potentials of the spherical sensor and nearby conductors are ... Incoming data are continuously monitored by algorithms in the software to ..... together with FM6 (Salsa) by a Soyuz-Fregat rocket from Baikonur. ...

UK PubMed Central (United Kingdom)

SUMMARYIncreasingly multiple outcomes are collected in order to characterize treatment effectiveness or to evaluate the impact of large policy initiatives. Often the multiple...Full Text Available

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... with the loosening of Bush-era restrictions on stem cell research, a move that was widely hailed by the ... The first two explore the contentious debate over stem cell research. Using a series of intervie...

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... The measured elastic modulus was fairly close to the predicted value, but the ultimate compressive strength (UCS) was quite a bit below the MSC ...

UK PubMed Central (United Kingdom)

SummaryWe consider the problem of estimating the effect of exposure on multiple continuous outcomes, when the outcomes are measured on different scales and are nested within multiple...Full Text Available

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... abundance though an effect on escapement. The lobster aquaculture model continues to be updated as new biological ... become available. A monograph on the economics of aquaculture is near completion....

UK PubMed Central (United Kingdom)

Training of health professionals commonly involves multiple sites in order to best utilize the available clinical material. However, this makes it difficult to achieve continuity in the presentation...Full Text Available

Science.gov (United States)

Eight units (low-power model Z-12's) were purchased, all for installation at continuously- operating stations in the Los Angeles prototype Dense GPS ...

Energy Technology Data Exchange (ETDEWEB)

Acute thoracic aortic injuries account for up to 10-20% of fatalities in high-speed deceleration road accidents and have an estimated immediate fatality rate of 80-90%. Untreated survivors to acute trauma (10-20%) have a dismal prognosis: 30% of them die within 6 hours, 40-50% die within 24 hours, and 90% within 4 months. It was investigated the diagnostic accuracy of Helical Computed Tomography (Helical CT) in acute traumatic injuries of the thoracic aorta, and the role of this technique in the diagnostic management of trauma patients with a strong suspicion of aortic rupture. It was compared retrospectively the chest Helical CT findings of 256 trauma patients examined June 1995 through August 1999. Chest Helical CT examinations were performed according to trauma score, to associated traumatic lesions and to plain chest radiographic findings. All the examinations were performed with no intravenous contrast agent administration and the pitch 2 ...

Environmental Research Database

DescriptionThe initiative on risk assessment and toxicology arose in 1995 when the limitations of current methods of risk assessment and the possibilities offered by new options were identified. Government Departments agreed to explore with the Research Councils how a joint strategy could be focused on the Departments' policy needs. In October 2002 the Steering Committee reviewed the work of IGHRC and recommended that the Initiative should continue for a further three years (October 2003 - September 2006 [continued...

Energy Technology Data Exchange (ETDEWEB)

The continuous bioprocessing of simulated steam-stripped sulfite pulp mill evaporator condensates using Candida utilis to produce single cell protein has been studied. At 32 degrees C, processing can be conducted at space velocities of up to 0.43 hr/sup -1/ with over 90% removal of acetic acid present at an initial concentration of 2 g/liter. (Refs. 16).

Energy Technology Data Exchange (ETDEWEB)

This paper describes New York State Electric and Gas Corporation`s concept for a comprehensive, centrally located data system for management of their continuous emission monitoring systems (CEMS) data. The topics of the paper include the power system`s mix of generating units; data reporting requirements; data base management; nitrogen oxides compliance tracking; sulfur dioxide, nitrogen oxides, carbon dioxide and flow monitoring; and allowance tracking.

Energy Technology Data Exchange (ETDEWEB)

This quarterly report covers the period from January 1, 2005 through March 31, 2005. It covers: technical development, permitting status, engineering status, construction status, operations summary and marketing support activities for this period. Plant startup is still continuing. Testing of admixtures to enhance extrusion and SDA wetting is continuing. Efforts are underway to improve plant availability.

UK PubMed Central (United Kingdom)

AimsTwo-dimensional echocardiographic (2DE) continuity-equation derived aortic valve area (AVA) in aortic stenosis (AS) relies on non-simultaneous measurement of left ventricular...Full Text Available

Environmental Research Database

ObjectivesThe overall aim of the proposed research is explicit in the project title, i.e. the creation of a map of current vertical land movements in the UK based on an optimal combination of absolute gravity (AG) and continuous GPS (CGPS). This is consistent with specific objective (ii) of WP1.9 of the Oceans 2025 programme and is related to priority topic area 4 (application of satellite geodesy to sea level science) of the NERC Strategic Ocean Funding Initiative (SOFI). From long term geological an [continued...]DescriptionThe proposed research aims to create a map of current vertical land movements in the UK based on an optimal combination of estimates from two geodetic surveying and monitoring techniques; the measurement of absolute gravity (AG) and the use of high precision, continuous GPS (CGPS) observations. From long term geological and geophysical studies, vertical land movements in the UK are thought to be of the ...

Science.gov (United States)

This document contains 142 papers on PT3 (Preparing Tomorrow's Teachers to use Technology) from the SITE (Society for Information Technology & Teacher Education) 2002 conference. Topics covered include: a technology in urban education summit; student professional development; meeting NCATE (National Council of Teachers of English) standards; faculty use of WebCT; preparing teachers for the digital age; technology in K-8 multicultural classrooms; using immersive 360 degree images; consortium building; student evaluation; technology fellows; incentives that facilitate institutional change; impact of a temporary grant; a consortium for outstanding achievement in teaching with technology; changes implemented after technology professional development sessions; Web-based modules for teaching mathematics to minority students; student teaching technology sites; preservice teachers design technology-enhanced learning experiences; planning, implementing, evaluating, and reflecting on ...

British Library Electronic Table of Contents (United Kingdom)

This paper describes a state-of-the-art online monitoring system using multivariate statistical technologies for continuous steel casting process, which was commissioned at Dofasco's No. 2 caster to provide consistent indication of process health for caster's start-up, continuous production and transitional operations. The paper particularly focuses on development of a novel scheme to synchronize process trajectories for monitoring specific transitional operations such as equipment or steel product grade changes. The proposed scheme is demonstrated by several industrial examples with the results showing good detectability of various process abnormalities. With the aid of this fully integrated, innovative monitoring system, Dofasco has generated significant value through improved productivi...

International Nuclear Information System (INIS)

A comparison is made of the response of a count ratemeter and a pulse counter using the mathematical tool of the Z transform. Transform Z is used for the solution of the convolution integral interpreting the analog output of the count ratemeter used for recording characteristic radiation, excited in the moving beam. The comparison of count rates obtained by the count ratemeter during continuous analysis and the pulse counter during discontinuous measurement gave the transfer function of the count ratemeter in the actual range of count rate. Also discussed is the use of the transfer function for localizing concentration changes in the sample. The use of the described method is demonstrated on the determination of the tin content in tungsten using continuous radionuclide X-ray fluorescence analysis. (B.S.).

CERN Document Server

The optical birefringence of rod-like nematogens (7CB, 8CB), imbibed in parallel silica channels with 10 nm diameter and 300 micrometer length, is measured and compared to the thermotropic bulk behavior. The orientational order of the confined liquid crystals, quantified by the uniaxial nematic ordering parameter, evolves continuously between paranematic and nematic states, in contrast to the discontinuous isotropic-to-nematic bulk phase transitions. A Landau-de Gennes model reveals that the strength of the orientational ordering fields, imposed by the silica walls, is beyond a critical threshold, that separates discontinuous from continuous paranematic-to-nematic behavior. Quenched disorder effects, attributable to wall irregularities, leave the transition temperatures affected only marginally, despite the strong ordering fields in the channels.

UK PubMed Central (United Kingdom)

Albeit the considerable progress that has been made both in our understanding of the pathophysiology of acute renal failure (ARF) and in its treatment (continuous renal replacement therapies), the morbidity...Full Text Available

UK PubMed Central (United Kingdom)

The Joint Commission on Accreditation of Hospitals (JCAH) has continuously emphasized improvement in the quality of care provided in hospitals as the central purpose of the accreditation process. In...Full Text Available

UK PubMed Central (United Kingdom)

A continuous stream of activating and repressing signals is processed by the transcription complex paused at the promoter of the c-myc proto-oncogene. The general transcription factor...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCholera has claimed many lives throughout history and it continues to be a global threat, especially in countries in Africa. The disease is listed as one of three internationally...Full Text Available

UK PubMed Central (United Kingdom)

This annual review focuses on invertebrate model organisms, which continue to yield fundamental new insights into mechanisms of aging. This year, the budding yeast has been used to understand how asymmetrical...Full Text Available

Science.gov (United States)

The Second International Seminar on Horizontal Steam Generator Modelling was arranged to continue the international cooperation that was started during the first seminar in March 1991. The main topics of the seminar were: (1) further experimental results ...

UK PubMed Central (United Kingdom)

Digital information flow within the intensive care unit (ICU) continues to grow, with advances in technology and computational biology. Recent developments in the integration and archiving of these...Full Text Available

UK PubMed Central (United Kingdom)

The classic evolutionary theory of aging explains why mortality rises with age: as individuals grow older, less lifetime fertility remains, so continued survival contributes less to reproductive fitness....Full Text Available

UK PubMed Central (United Kingdom)

The pyrethroid knockdown resistance gene (kdr) has become widespread in Anopheles gambiae in West Africa. A trial to test the continuing efficacy of insecticide-treated...Full Text Available

UK PubMed Central (United Kingdom)

Preterm and low birthweight (PTLBW) continues to be a major cause of mortality and morbidity across the world. In recent years, maternal periodontal disease has been implicated as a risk factor for...Full Text Available

UK PubMed Central (United Kingdom)

BACKGROUND: Although the effectiveness of influenza vaccination in high-risk groups has been proven, vaccine coverage continues to be less than 50% in The Netherlands. To improve vaccination rates,...Full Text Available

Science.gov (United States)

The continuing rapid increase in available computing power has not reduced the importance of efficient methods of optical system assessment for automatic lens design. On the contrary, the new capabilities simply show that truly automatic optical design wi...

Science.gov (United States)

Feb 7, 2011 ... The potentials of the spherical sensor and nearby conductors are controlled ... Incoming data are continuously monitored by algorithms in the software ... together with FM8 (Tango) by a Soyuz-Fregat rocket from Baikonur. ...

UK PubMed Central (United Kingdom)

BackgroundAlthough considerable progress has been made in the treatment of chronic kidney disease, compromised quality of life continues to be a significant problem for patients...Full Text Available

UK PubMed Central (United Kingdom)

Arriving at a firm diagnosis of neurosarcoidosis continues to pose serious problems, particularly when evidence of granulomatous disease outside the nervous system is lacking. The commonest mode of...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

ResumeObjectif determiner dans une etude randomisee l'impact d'un enregistrement continu du glucose sous-cutane pendant 48 heures sur le controle glycemique trois mois plus tard chez des patients presentant un diabete de type 1 (DT1) ou de type 2 (DT2). Methodes Quarante-huit patients avec un mauvais equilibre glycemique (HbA1c : 8-10,5 %) ont beneficie d'un enregistrement continu du glucose sous-cutane pendant 48 heures avec le systeme GlucoDay (A. Menarini Diagnostics) et ont ete randomises en deux groupes : ajustement de traitement en fonction de l'autosurveillance glycemique capillaire (groupe ASG) ou du profil d'enregistrement continu du glucose sous-cutane (groupe CGM). Le dosage d'HbA1c et le port du GlucoDay ont ete renouveles trois mois plus tard. Resultats Trente-quatre patients ...

UK PubMed Central (United Kingdom)

Few studies have examined energy metabolism during prolonged, strenuous exercise. We wanted therefore to investigate energy metabolic consequences of a prolonged period of continuous strenuous work...Full Text Available

Science.gov (United States)

To perform the localization project of WOLSUNG reactor fuel, mass-production system of irradiation-stable and sound fuel pellet must be established. The following subjects have been carried out to set up CANDU fuel fabrication process for continuous produ...

Science.gov (United States)

This report is a continuation of the former efforts to elucidate the behavior of ferrocement concrete in static and dynamic stress fields. The influence of various reinforcements on pre and post cracking of thin sections forms the main topic of this repor...

UK PubMed Central (United Kingdom)

AbstractExclusive breastfeeding of infants for the first 6 months of life with continued breastfeeding for at least 6 more months occurs only 11.9% of the time in the United States. Efforts...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Emissions of sulphur and nitrogen oxides are continuing to fall in Europe but rise in Asia, according to calculations based on individual countries' predictions of economic development. The upward trend is slower than in previous predictions. 2 refs., 2 figs., 2 tabs.

UK PubMed Central (United Kingdom)

The endoplasmic reticulum (ER) is a continuous membrane system comprising the nuclear envelope, ribosome-studded peripheral sheets and an interconnected network of smooth tubules extending throughout...Full Text Available

UK PubMed Central (United Kingdom)

The dissimilatory iron-reducing bacterium Geobacter metallireducens was found to require iron at a concentration in excess of 50 μM for continuous cultivation on nitrate. Growth...Full Text Available

UK PubMed Central (United Kingdom)

Highly pathogenic avian influenza and in particular the H5N1 strain has resulted in the culling of millions of birds and continues to pose a threat to poultry industries worldwide. The recent outbreak...Full Text Available

UK PubMed Central (United Kingdom)

New forms of payment, growing competition, the continued evolution of multiunit hospital systems, and associated forces are redefining the fundamental relationship between hospitals and physicians....Full Text Available

UK PubMed Central (United Kingdom)

Cimetidine 1 g daily is often continued for a fixed period beyond the time of healing of duodenal ulcer on the assumption that it might reduce the subsequent relapse rate. To test this, 194 patients...Full Text Available

UK PubMed Central (United Kingdom)

The continuous addition of toluene as a solute of treated ballast water from oil tankers into a well-defined estuary facilitated the study of the dynamics of dissolved hydrocarbon metabolism in seawater....Full Text Available

British Library Electronic Table of Contents (United Kingdom)

We investigate the default time of a firm when a stochastic discount factor is used so that both diffusion and regime switching risks are priced. We establish the relationship between the probability distribution of the default time and the solution of a system of coupled partial differential equations.

UK PubMed Central (United Kingdom)

The search for cancer treatment continues to be a global effort. As part of this global effort, many natural products have been tested against cancer cell lines, mostly from tropically located plants....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Work continued on the correlations of catalytic activity of metals and surface structure. Work is described in the following areas: CO oxidation on a Cu/Rh(100) Bimetallic catalysts; electronic properties of bimetallic surfaces; and reflection absorption spectroscopy of bimetallic surfaces. 5 figs. (CBS)

UK PubMed Central (United Kingdom)

Activation of beta-adrenergic or muscarinic acetylcholine receptors expressed in transfected cells or epidermal growth factor receptors in human keratinocytes produces 15% to 200% changes in cellular...Full Text Available

UK PubMed Central (United Kingdom)

Huntington's disease (HD) is one of several neurodegenerative disorders caused by expansion of CAG repeats in a coding gene. Somatic CAG expansion rates in HD vary between organs, and the greatest instability...Full Text Available

Science.gov (United States)

... Steady State 16.0-28.0 5.05 to 5.36 0 Key switch turned on. ... version may have been the better choice since the acousto-optic modulator also ...

International Nuclear Information System (INIS)

Continuous ambulatory peritoneal dialysis (CAPD) is a generally well-tolerated treatment. However, some patients exhibit such complications as to prevent the continuation of treatment. Peritonitis is the major problem, but the continuation of treatment may also be undermined by different complications, such as peritoneal leakage, hernia, catheter malfunctioning, and scrotal-penile edema; a careful investigation of the patient is always needed in such cases. From November 1985 to February 1990, we examined 20 patients, who had presented with different types of complications in the course of dialysis. Peritoneography demonstrated 3 cases of abdominal hernias, 2 cases of patency of the peritoneal-vaginal duct, and 2 cases of catheter obstruction. Peritoneal CT allowed the identification of leakage in 3 patients, while the combined use of the two techniques showed adhesions or pathologic peritoneal recesses in 7 cases. In 3 ...

UK PubMed Central (United Kingdom)

BackgroundThe elevated serum and peritoneal cytokine concentrations responsible for the systemic response syndrome (SIRS) and multiorgan failure in patients with severe acute pancreatitis...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundChronic non-specific musculoskeletal pain (CNSMSP) may develop in childhood and adolescence, leading to disability and reduced quality of life that continues into adulthood....Full Text Available

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... and retrieve an AED until you have performed CPR for about 2 minutes. 3. Carefully place the ... more breaths. The chest should rise. 9. Continue CPR (30 chest compressions followed by 2 breaths, then ...

UK PubMed Central (United Kingdom)

Artificial selection and experimental evolution document natural selection under controlled conditions. Collectively, these techniques are continuing to provide fresh and important insights into the...Full Text Available

Science.gov (United States)

45 Public Welfare 3 2010-10-01 2010-10-01 false Appendix A to Part 611 A Appendix A to Part 611 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE...

International Nuclear Information System (INIS)

This paper presents anew design concept for a gamma irradiation plant for the continuous processing of pumpable liquids. Typical applications of such a plant include: the irradiation vulcanisation of natural latex rubber; disinfection of municipal sewage sludge for agricultural use; sterilisation of liquids in the pharmaceutical and cosmetics industries; industrial processing of bulk liquids The authors describe the design and operation of the latex irradiator now operating on a small production scale in Malaysia and proposed developments. The design allows irradiation processing to be carried out under an inert or other gaseous environment. State-of-the-art computer control system ensures the fully automatic processing operation needed by industrial computers.

International Nuclear Information System (INIS)

If trends from the past continue into the future, the major increase in the use of energy will come from the developing nations. If the industrialization of the Third World continues to be based on the burning of fossil fuels, the impact on the global climate from these sources alone will be substantial. Statistical information supporting the above statements is presented. The conclusion is reached that improving the efficiency of energy use is not sufficient to avert climatic changes. The accelerated and worldwide use of nuclear power is essential and, if prudently used, can become, contrary to the recommendations of the Brundtland Commission, the basic energy source fuelling future sustainable developments of the world. (author).

Energy Technology Data Exchange (ETDEWEB)

As a consequence of the expanded use of long term hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) treatments and extended life spans, complications of end-stage renal disease and dialysis treatments are being encountered with increasing frequency in these patients. Computed tomography can accurately depict many of the potential complications of end-stage renal disease on dialysis. This article presents the abdominal CT findings of 429 end-stage renal disease patients who are on either hemodialysis or continuous ambulatory peritoneal dialysis treatment.

Energy Technology Data Exchange (ETDEWEB)

Survey report: The Petroleum Association for the Conservation of the Canadian Environment is an organization of petroleum refiners that works closely with the Canadian government to set realistic air pollution control standards for refinery emissions. To date, the refiners have made a substantial investment in pollution abatement equipment. As a result, there have been no major pollution incidents traceable to refinery emissions. In the future, it will be essential that refiners continue to invest in air pollution abatement measures and continue to cooperate with the government in setting achievable pollution control standards. (1 photo, 1 table)

Energy Technology Data Exchange (ETDEWEB)

In this article, a continuous stabilization process was used to make flame resistant fibers from polyacrylonitrile (PAN) fibers. The effect of the stabilization time and the stretching process during the stabilization process on the physical properties and flammability of the resultant flame resistant fibers was studied. Increased drawing of PAN fibers during the continuous stabilization process was found to decrease the diameter and increase the tensile strength in the resultant flame resistant fibers. These fibers also had higher density. There were no absolute relationships seen between flame-resistance and the formation of stable ladder polymers, density, and oxygen content. ((orig.))

International Nuclear Information System (INIS)

Processes of production and purification (necessary for fabricating fuel elements) of powdery uranium dioxide with particle size up to 1000 #mu#m and more have been studied. Developed is continuous process of UO_2 production with above particle size by converting uranium hexafloride into UO_2 solid particles in fluidized bed while their interaction with water vapor and hydrogen on the uranium dioxide nucleus material. The method allows to conduct continuous selection from the apparatus of UO_2 powder fraction with particle size near 1000 #mu#m without nucleus material additional feed.

Energy Technology Data Exchange (ETDEWEB)

This paper presents a unique method, currently under evaluation, that can continuously track pipeline operation providing essentially instantaneous responses to leaks or ruptures without causing a pressure drop or energy loss. Using the highly linear characteristics of a very accurate and repeatable meter and then correlating it to a second identical unit, a dynamic leak detection system is planned that can be retrofitted on existing pipelines without a major construction effort nor destroying the integrity of the existing transmission line. Initial tests performed on a crude oil transmission line verified the equipment's performance and established that the repeatability limits are sufficient to continue development of the concept.

British Library Electronic Table of Contents (United Kingdom)

The quality of the end product from andrology services continues to lack consistency and in some cases fails to meet the needs of the end users (patients or clinicians). Results of external quality assessment (EQA) schemes continue to show unacceptably wide variation for the results of a single specimen. Some laboratories are able to show that the results of semen analyses relate to both natural and assisted pregnancy and are therefore useful in the management of the infertile couple, whereas others claim that their value is limited to the identification of severe male factor infertility. With wide variation in standardisation of methodology, levels of staff training and quality assurance, it is entirely understandable that such discrepancies persist. The following article proposes that Qu...

Energy Technology Data Exchange (ETDEWEB)

The dynamics of the controlled environment conditions in the SVET-4 space greenhouse model were investigated, using computerized equipment to continuously measure and collect the values of the inside environment parameters, which were then sent to earth. The on-ground analysis of telemetric data for the first 29 days indicated that radishes and the Chinese cabbage plants planted in SVET-4 grew under normal temperature conditions, but in insufficient substrate moisture. After supplying the necessary quantity of water, the analysis of the first 54 days of experiment is continuing. 2 refs.

Science.gov (United States)

Continuous wave lasing operation with the shortest wavelength for semiconductor lasers was obtained from AlGaInP double heterostructure lasers at 77 K. The structure was grown by metalorganic vapor phase epitaxy. Lasing wavelength was 583.6 nm (yellow). Threshold current was 43 mA (1.9 kA/cm/sup 2/). Magnesium was adopted as a p-type dopant, and was proved to be preferable for a high aluminum composition AlGaInP cladding layer.

Energy Technology Data Exchange (ETDEWEB)

The first stage of the continuous coal hydrogenation unit has been used to test a number of coals with different processing strategies. This work has shown that conversion increases with product recycle, however after the second pass the increase is small but operability of the reactor is considerably improved. A kinetic model for the aromatic saturation of the recycle solvent in the second stage has been developed and will be used in the selection of conditions for oil upgrading processes. New insights into the structural composition of coal derived materials have been made due to the refinement of chromatographic or solubility separation analyses into routine operations and the development of a new technique in NMR spectroscopy.

Energy Technology Data Exchange (ETDEWEB)

This paper discusses the successful implementation of automatic control in the Wattenberg Gas Field in northern Colorado. Also discussed is the use of solar powered Amocams equipment to affect continuous monitoring and control of these tight gas wells. The control system includes an algorithm which continuously adjusts the production cycling based on changes in the individual well's producing pressures and flow rates. This strategy has been successful in enhancing production and reducing the number of wells logged off due to excessive fluid buildup. The benefits derived from this system are enumerated and the impacts on field operations are discussed.

Energy Technology Data Exchange (ETDEWEB)

The coal transportation industry has played an integral role in determining coal markets, particularly in recent years, as the industry has evolved from cost-based pricing to market-based pricing. Aggressive pricing by Western rail carriers has caused extensive changes in coal marketing patterns in the Midwest. Multi-modal barge deliveries of Western and Appalachian coals have also played a significant, though lesser, role in changing coal markets. Eastern rail carriers have generally lagged in their aggressive pursuit of new coal markets and, to date, few changes in coal markets have been realised. The historic dominant role of transportation in shaping markets for coal will continue into the future as the utility industry contends with the effects of CAAA compliance and deregulation and as the coal industry contends with regional coal displacements and major imbalances in supply and demand. The dominance of rail transportation in defining coal distribution ...

Energy Technology Data Exchange (ETDEWEB)

This report summarizes the results of research conducted during the sixteen month continuation of a program to develop rechargeable zinc-air batteries for electric vehicles. The zinc-air technology under development incorporates a metal foam substrate for the zinc electrode, with flow of electrolyte through the foam during battery operation. In this soluble'' zinc electrode the zincate discharge product dissolves completely in the electrolyte stream. Cycle testing at Lawrence Berkeley Laboratory, where the electrode was invented, and at MATSI showed that this approach avoids the zinc electrode shape change phenomenon. Further, electrolyte flow has been shown to be necessary to achieve significant cycle life (> 25 cycles) in this open system. Without it, water loss through the oxygen electrode results in high-resistance failure of the cell. The Phase I program, which focused entirely on the zinc electrode, elucidated the conditions necessary to ...

Energy Technology Data Exchange (ETDEWEB)

This report contains the operation procedures in extreme situations and lessons learned from blackouts, based on a mandate given by the Operations Committee. Nordic TSOs have had common rules and principles for system operation i.e. System Operation Agreement since the late 1990s. The rules have been revised according to the system security and market changes and needs. The collaboration between system operators is regular and fruitful. The knowledge and capability to manage extreme situations of the Nordic power system has continuously increased and the recent blackouts did not show major deficiencies in operation practices. Regardless of the existing good collaboration it is important to continue development in the future in order to ensure high system security. Important development areas are security of reserve supervision and coordination of calculation procedures for transmission limits, enhancement of data exchange routines between ...

Science.gov (United States)

This paper proposes an optimization algorithm to reduce the distortion produced in the loop-filter of Continuous-Time Sigma-Delta Modulators. The aim of the algorithm is to find the loop-filter implementation that minimizes distortion at the output of the modulator, by modifying the output swing of every integrator. The algorithm is implemented in Matlab as an evolutive searching. During each step of the searching, the algorithm evaluates the harmonical distortion of a tone when it is applied to the modulator with a certain loop-filter implementation. The output of the algorithm is an optimum linear state-space representation of the loop-filter. This particular state-space representation leads to minimum distortion at the output of the modulator when the loop-filter is implemented with some specific circuitry previously defined. As long as the search is of evolutive type, the solution represents a local minimum only. The algorithm computes a random guess solution ...

Energy Technology Data Exchange (ETDEWEB)

This paper reported on a study in which hydrogen was produced by fermentation of biomass. A continuous process using a non-sterile substrate with a readily available mixed microflora was used on heat treated digested sewage sludge from a wastewater treatment plant. Hydrogen was produced from waste sugar at a pH of 5.2 and a temperature of 37 degrees C. An experimental setup of three 5.5 L working volume continuously stirred tank reactors (CSTR) in different stirring speeds were constructed and operated at 7 different hydraulic retention times (HRTs) and different organic loading rates (OLR). Dissolved organic carbon was examined. The results showed that the stirring speed of 135 rpm had a beneficial effect on hydrogen fermentation. The best performance was obtained in 135 rpm and 8 h of HRT. The amount of gas varied with different OLRs, but could be stabilized on a high level. Methane was not detected when the HRT was less than 16 h. The study ...

Energy Technology Data Exchange (ETDEWEB)

Beginning in the 1940's and continuing through the 50's and early 60's, nuclear devices were tested by aerial detonation in the United States and other countries around the world. Cesium-137 (/sup 137/Cs) is one of the most important radionuclide by-products due to its abundance and slow decay (30-year half-life). The uptake of /sup 137/Cs in animal tissue is the result of its similarity to potassium. The somatic and genetic effects of /sup 137/Cs, along with its effect on reproductive cells, can pose great hazards to wildlife species. A reported buildup of /sup 137/Cs in white-tailed deer in the lower coastal plain of Georgia during the 1960's was followed by a gradual decline during the 1970's. Although numerous studies have involved terrestrial mammals of Georgia, few have involved aquatic mammals such as the river otter. With continued atmospheric testing by some foreign countries and the ...

CERN Document Server

A sequential problem in decentralized detection is considered. Two observers can make repeated noisy observations of a binary hypothesis on the state of the environment. At any time, observer 1 can stop and send a final binary message to observer 2 or it may continue to take more measurements. Every time observer 1 postpones its final message to observer 2, it incurs a penalty. Observer 2's operation under two different scenarios is explored. In the first scenario, observer 2 waits to receive the final message from observer 1 and then starts taking measurements of its own. It is then faced with a stopping problem on whether to stop and declare a decision on the hypothesis or to continue taking measurements. In the second scenario, observer 2 starts taking measurements from the beginning. It is then faced with a different stopping problem. At any time, observer 2 can decide whether to stop and declare a decision on the hypothesis or to ...

Environmental Research Database

ObjectivesThe objective of this meeting will be to interface the two ends of the particulate flow spectrum - those working to understand the fundamentals of granular flows and those attempting to control particulate flows in an industrial setting - to develop solutions to the complex problems presented by dense granular flows. We will aim~%~~%~to provide a forum for the interface between practical users of particulate technology and the developers of theories for understanding granular flow;~%~to present [continued...]DescriptionIn practical situations such as those met in industry where segregation and mixing are important, understanding particulate flows is complex due to the presence of polydispersity, anisotropy and complex grain morphology. In attempting to model such systems, many of these features are generally ignored, except perhaps through empirical parameter fitting. Developing a theory to include these effects is a considerable ...

Environmental Research Database

ObjectivesThe primary aim is to enable China to address its energy and infrastructure issues in a sustainable manner, without hindering economic progress, with the UK benefiting from an enhanced uptake of its technology, knowledge and expertise through enhanced business opportunities and strengthened collaboration with key Chinese Institutions. ~%~~%~Objectives~%~1) To build capacity and capability in technology transfer and knowledge exploitation in Chinese and UK business and industry through practical, [continued...]DescriptionThe Chinese 11th Five-Year Plan considers Sustainable Energy Supply and Sustainable Built Environment as crucial for achieving sustainable development. Recognising the potential benefits, the UK government has actively encouraged international collaborations with China. Two Engineering Schools at Queen's University Belfast (QUB), with internationally recognised research excellence in the Built Environment and in Electric ...

Energy Technology Data Exchange (ETDEWEB)

A new methodology for three-dimensional (3-D) numerical modeling of the continuous steel casting process is presented and evaluated. The results are compared with available experimental data obtained in a water-oil mold model for various flow rates and immersion depths of the submerged entry nozzle. The water-oil interface pattern at the top of the mold is also investigated. Wave formation and evolution in time is simulated with a volume tracking method. The predicted flow field inside the mold exhibits quite satisfactory agreement with the corresponding measurements, whereas some quantitative differences are observed referring to the final wave amplitude at low casting speeds. Conclusions of scientific and engineering importance concerning both the computer algorithm and the mold performance are also drawn.

International Nuclear Information System (INIS)

This paper discusses how the U.S. Liquid Metal Reactor Development Program has been restructured to carry out R and D on advanced reactor technology. The program gives particular emphasis to improvements to reactor safety. The new directions are based on the technology of the integral fast reactor (IFR). Much of the basis for superior safety performance using IFR technology has been experimentally verified and aggressive programs continue in EBR-II and TREAT. Progress has been made in demonstrating both the metallic fuel and the new electrochemical processes of the IFR. The FFTF facility is converting to metallic fuel; however, FFTF also maintains a considerable U.S. program in oxide fuels. In addition, generic programs are continuing in steam generator testing, materials development, and with international cooperation, aqueous reprocessing.

Energy Technology Data Exchange (ETDEWEB)

This article identifies the imperatives behind the need to move away from teaching based on the transmission of a lot of facts to teaching that enables students to become lifelong learners. It reminds us that the over-riding goal is an education process that maximizes the ability of teachers to teach well and of students to learn effectively. It argues that the necessary reform process can only be successful if the three components of an education programme--the curriculum, teaching strategies and assessment--are reformed simultaneously to ensure that each is designed to produce more effective teaching and learning. It points to the literature that tells us what we know about factors affecting student behaviour and, in particular, notes the crucial factor of student perception of the requirement of the assessment regime. It recommends that Biggs' model of constructive alignment is used as the organizing principle of continuing reform.