14c-pbde accumulation biological: Topics by WorldWideScience.org

A biological standard for measurement of blood coagulation factor VIII activity

The biological accumulation of heavy metals and cesium, strontium, and uranium in plants is discussed. The role of nutrient deficiencies and foliar treatments of manganese and iron compounds is described.

1995-12-01

2

Regulating the intensity of radionuclide transfer to the yield

Because of the instability of Factor VIII (antihaemophilic factor) in plasma in vitro, and since evidence has accumulated that the level of activity varies significantly between samples...Full Text Available

1971-01-01

3

Migration of the long-lived radionuclides in soil-plant system under conditions of 30-km zone

As a result of the accident at the Chernobyl Power Plant the larger part of Belarus turned out to be polluted by radionuclides. At present isotopes of Cs, Sr and Pu, characterized by long half-lives are most dangerous for the health of the population of the polluted territories. The aim of the present work was to characterize plant species with high "1"3"7Cs and "9"0Sr accumulation ability and to determine the dependence of the accumulation on the treatment with biologically active substances. (author)

1995-12-01

4

Ion beam induced damage and element loss during a microanalysis of biological tissue

Field experiments were conducted in the 30-km zone of Gomel's region of the Byelorussia to study factors aecting a biological radionuclide accessibility. A contamination density by radiocesium equaled 2,7-9,9 MBk/m"2, strontium 90 - 0,3-0,5 MBk/m"2 in 1991. A sowing of oats barley, lupin was carried out. It was shown that radionuclide accumulation by agricultural plants was determined basically by biological peculiarities of plants in greater degree than by the contamination density. It was shown that strontium 90 migration from the soil was more intensive than that of radiocesium. 8 tabs.

1992-05-15

5

Chemical aspects of uranium behavior in soils: A review

Specimen damage and element loss induced by 3 MeV proton and 2 MeV alpha particle bombardment of thin sections of freeze-dried kidney tissue and embedding medium have been studied. Yields of ions scattered from H and C, and characteristic X-rays were measured versus accumulated charge, for curent densities in the range from 8x10{sup -15} to 1.1x10{sup -11} A/{mu}m{sup 2}. Structural damage, dissolouration and loss of S, Cl, C and H have been observed. Implications of this study for ion beam microanalysis of biological tissues are discussed with particular reference to the results for H loss. (orig.).

1991-03-01

6

British Library Electronic Table of Contents (United Kingdom)

Uranium has varying degrees of oxidation (+4 and +6) and is responsive to changes in the redox potential of the environment. It is deposited at the reduction barrier with the participation of biota and at the sorption barrier under oxidative conditions. Iron (hydr)oxides are the strongest sorbents of uranium. Uranium, being an element of medium biological absorption, can accumulate (relative to thorium) in the humus horizons of some soils. The high content of uranium in uncontaminated soils is most frequently inherited from the parent rocks in the regions of positive U anomalies: in the soils developed on oil shales and in the marginal zone of bogs at the reduction barrier. The development of nuclear and coal-fired power engineering resulted in the environmental contamination with uranium....

2011-01-01

7

Spark decomposition of SF/sub 6/

Biological Surface-Active Substance

Gas-insulated systems employing SF/sub 6/ are utilized in a variety of applications in power delivery systems. Because electric arcs, sparks or corona can decompose SF/sub 6/ into by-products having chemical properties different from SF/sub 6/, environmental concerns arise regarding inadvertent human exposures to electrically-decomposed SF/sub 6/. Biological assays in our laboratory using mammalian cell culture systems have revealed that SF/sub 6/, spark-decomposed under specific experimental conditions, can produce cell death. Chemical analysis of spark-decomposed SF/sub 6/ has identified the major decomposition pathways and by-products. Biological testing of individual by-products or by-product mixtures has indicated that these major decomposition products may not account for the majority of the cell killing effects seen in our assays. Further experiments have suggested that S/sub 2/F/sub 10/ may be produced and ...

1989-07-01

8

International Science & Technology Center (ISTC)

Development of biological preparation with surfactant activity

9

The mechanism of metal nanoparticle formation in plants: limits on accumulation

Studies on inherited sterility induced in the progeny of gamma irradiated cotton leaf worm, Spodoptera littorals (Boisd.)

Metal nanoparticles have many potential technological applications. Biological routes to the synthesis of these particles have been proposed including production by vascular plants, known as phytoextraction. While many studies have looked at metal uptake by plants, particularly with regard to phytoremediation and hyperaccumulation, few have distinguished between metal deposition and metal salt accumulation. This work describes the uptake of AgNO{sub 3}, Na{sub 3}Ag(S{sub 2}O{sub 3}){sub 2}, and Ag(NH{sub 3}){sub 2}NO{sub 3} solutions by hydroponically grown Brassica juncea and the quantitative measurement of the conversion of these salts to silver metal nanoparticles. Using X-ray absorption near edge spectroscopy (XANES) to determine the metal speciation within the plants, combined with atomic absorption spectroscopy (AAS) for total Ag, the quantity of reduction of Ag{sup I} to Ag{sup 0} is reported. Transmission electron microscopy (TEM) ...

2009-08-15

10

Sediment trap fluxes and benthic recycling of organic carbon, polycyclic aromatic hydrocarbons, and polychlorobiphenyl congeners in Lake Superior

Full - grown pupae of the cotton leaf worm Spodoptera littorals (Boisd.) were gamma - irradiated with low doses of 25,50,75, or 100 Gy for male line and with 50 or 100 Gy for female line . The effects on reproduction, development and sex ratio were the biological aspects studied among P1,F1,F2 and F 3 generations . Also, the effects of dose accumulation applied grown male pupae through two or three filial generations and the retarded influence on their F1,F2,and F 3 progeny were examined. In another trial the histological examinations for ovaries and testes of irradiated parents and for their generation were made . The F1 males were more sterile than irradiated parental males while F1 females were more fertile than their irradiated parental females. Irradiation of P1 males did not clearly affect neither the percentage of mated females nor the average number of spermatophores per mated female among the individuals of P1,F1,F2 and F 3 ...

11

[Comparative study on the historical evolution of field surgery between China and Russia].

Sediment trap fluxes of solids, organic carbon, polycyclic aromatic hydrocarbons (PAHs), and polychlorinated biphenyls (PCBs) were measured in Lake Superior in 1984 and 1985. Mass fluxes from surface waters ranged from 0.14 to 1.1 g/m{sup 2}{center dot}day and increased near the lake floor due to resuspension of surficial sediment and horizontal transport in the benthic nepheloid layer. Organic matter fluxes from surface water ranged from 60 to 90 mg of C/m{sup 2}{center dot}day, with {approximately}5% of organic carbon settling from surface waters accumulating in bottom sediments. Concentrations of PCBs and PAHs are enriched 10-100 times on settling particles relative to those on suspended particles. Resultant settling fluxes are 10-100 times greater for several PCB and PAH compounds than net accumulation rates in bottom sediments, indicating the effective and rapid recycling in the benthic region. Biological packaging of ...

1991-03-01

12

Non-destructive Imaging of Individual Bio-Molecules

Russian field surgery with its long history and distinctive characteristics has accumulated great experience in the long-time practice of warfare. Chinese field surgery was established and developed on the basis of studying from the Russian model, which opened up new areas of traffic medicine, molecular traumatology and assessment of biological effects on weapon destruction and carried out in-depth research on wound ballistics, blast injury, burns and combined injury etc. through decades of construction with continuous development and innovation, and a series of major achievements have been made in these fields. By making comparative study on the historical evolution, structure system, characteristics of campaigns and development of society between Chinese and Russian field surgery, it can be found that there are great gaps between them and we should strengthen the research for more rapid development. PMID:20510098

2010-03-01

13

CERN Document Server

Radiation damage is considered to be the major problem that still prevents imaging an individual biological molecule for structural analysis. So far, all known mapping techniques using sufficient short wave-length radiation, be it X-rays or high energy electrons, circumvent this problem by averaging over many molecules. Averaging, however, leaves conformational details uncovered. Even the anticipated use of ultra-short but extremely bright X-ray bursts of a Free Electron Laser shall afford averaging over 10^6 molecules to arrive at atomic resolution. Here we present direct experimental evidence for non-destructive imaging of individual DNA molecules. In fact, we show that DNA withstands coherent low energy electron radiation with deBroglie wavelength in the Angstrom regime despite a vast dose of 10^8 electrons/nm^2 accumulated over more than one hour.

2009-01-01

14

New [{sup 99m}Tc]-cytectrene amine compounds as specific brain imaging agents

New ["9"9"mTc]-cytectrene amine compounds as specific brain imaging agents

Lipophilic tertiary amines attached to cylcopentadienyl technetium-99m tricarbonyl (cytectrene) have been prepared with high radiochemical yield and purity. Biodistribution studies in mice showed that [{sup 99m}Tc]-cytectrenes, containing in their structure an N-methylpiperidine, were accumulated in the brain up to 2.8% of injected dose with high brain-to-blood ratios at 15 min p.i. They therefore indicate some potential as brain imaging agents. It has to be pointed out that the N-methylpiperidine ester showed similar biological behaviour as the keto derivatives. This indicates that the conversion to polar metabolite(s) via hydrolysis of the ester group - as described for [{sup 99m}Tc]-ECD -is not essential for brain retention. (Author).

1995-02-01

15

Long-distance transport, vacuolar sequestration, tolerance, and transcriptional responses induced by cadmium and arsenic

Lipophilic tertiary amines attached to cylcopentadienyl technetium-99m tricarbonyl (cytectrene) have been prepared with high radiochemical yield and purity. Biodistribution studies in mice showed that ["9"9"mTc]-cytectrenes, containing in their structure an N-methylpiperidine, were accumulated in the brain up to 2.8% of injected dose with high brain-to-blood ratios at 15 min p.i. They therefore indicate some potential as brain imaging agents. It has to be pointed out that the N-methylpiperidine ester showed similar biological behaviour as the keto derivatives. This indicates that the conversion to polar metabolite(s) via hydrolysis of the ester group - as described for ["9"9"mTc]-ECD -is not essential for brain retention. (Author).

16

British Library Electronic Table of Contents (United Kingdom)

Iron, zinc, copper and manganese are essential metals for cellular enzyme functions while cadmium, mercury and the metalloid arsenic lack any biological function. Both, essential metals, at high concentrations, and non-essential metals and metalloids are extremely reactive and toxic. Therefore, plants have acquired specialized mechanisms to sense, transport and maintain essential metals within physiological concentrations and to detoxify non-essential metals and metalloids. This review focuses on the recent identification of transporters that sequester cadmium and arsenic in vacuoles and the mechanisms mediating the partitioning of these metal(loid)s between roots and shoots. We further discuss recent models of phloem-mediated long-distance transport, seed accumulation of Cd and As and rec...

2011-01-01

17

Focused ion beam (FIB) milling of electrically insulating specimens using simultaneous primary electron and ion beam irradiation

Bioconversion of chicken wastes to value-added products

There is currently great interest in combining focused ion beam (FIB) and scanning electron microscopy technologies for advanced studies of polymeric materials and biological microstructures, as well as for sophisticated nanoscale fabrication and prototyping. Irradiation of electrically insulating materials with a positive ion beam in high vacuum can lead to the accumulation of charge, causing deflection of the ion beam. The resultant image drift has significant consequences upon the accuracy and quality of FIB milling, imaging and chemical vapour deposition. A method is described for suppressing ion beam drift using a defocused, low-energy primary electron beam, leading to the derivation of a mathematical expression to correlate the ion and electron beam energies and currents with other parameters required for electrically stabilizing these challenging materials.

2007-02-07

18

Bomb "1"4C and human radiation burden

Increasing quantities of chicken waste concerns the poultry industry because of escalating disposal costs and the potential for environmental pollution. Biological conversion of these wastes to valuable products such as methane and/or chemical feed-stocks appears to be feasible. Biomethanation of chicken waste by a sewage sludge microbial consortium produced as much as 69 mol% methane in the gas phase. Acetic and propionic acids were the major acids produced during the bioconversion. Addition of chelating agents and other micro-nutrients enhanced methane production and shifted the ratios of intermediates accumulated. Preliminary data indicate that more than 60% of the chicken waste carbon was converted and that the nitrogen-rich residue may have potential as a soil additive. (author).

1991-01-01

19

Application of biosorption and accumulation processes for metal separation and recovery from polluted industrial effluents for the purpose of environmental pollution abatement. Final report; Nutzung von Prozessen der Biosorption und Akkumulation zur Metallabtrennung und Rueckgewinnung aus belasteten Abwaessern mit dem Ziel der Umweltsanierung; Abschlussbericht

Following the publication (Stenhouse and Baxter, Nature; 267:828 (1977)) of the levels of bomb "1"4C and the residence times of carbon in the human body, excess radiation burdens from this radioisotope are evaluated under the assumption that no radiation dose, however small, can be regarded as entirely harmless biologically. The estimated annual absorbed dose attributable to "1"4C both natural and man-made for 1953-1973 and similar predicted figures for 1975-2025 are shown graphically. The cumulated doses to gonads (over 30 yr) and to bone marrow and bone-lining cells (over 60 yr) and also estimates of the biological damage to reproductive cells from "1"4C #beta#-irradiation (30 yr accumulated dose) are presented. It is concluded from both genetic and somatic considerations, that the potential human radiation burden due to artificially produced "1"4C calculated using the assumptions stated is certainly significant and, ...

20

Dispersion of Metals from Abandoned Mines and their Effect on Biota in the Methow River, Okanogan County, Washington: Final Report 2002-2003.

Fundamental investigations into the biosorption of environmentally relevant heavy metals were carried out with different microbial adsorbents, and processes were proposed for industrial effluents. In order to improve the technology of biosorption processes, attempts were made to improve the sorption efficiency of biological sorbents, and investigations were carried out on the immobilisation of biological adsorbents. (orig.) [Deutsch] Es wurden Grundlagenuntersuchungen zur Biosorption von umweltrelevanten Schwermetallen mit verschiedenen mikrobiellen Adsorbentien durchgefuehrt und an technischen Abwaessern Technologievorschlaege erarbeitet. Zur Verbesserung der Technologie von Biosorptionsprozessen wurden Moeglichkeiten der Steigerung der Sorptionsleistung von Biosorbentien erarbeitet und Untersuchungen zur Immobilisierung der biologischen Adsorbentien durchgefuehrt. (orig.)

1991-12-31

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The Biology of Phenolic Containing Vesicles

A study of mine-waste contamination effects on Methow River habitat on the eastern slopes of the north Cascade Mountains in Washington state, U.S.A., revealed impacts at ecosystem, community, population, individual, tissue, and cellular levels. Ore deposits in the area were mined for gold, silver, copper and zinc until the early 1950's, but the mines are now inactive. An above-and-below-mine approach was used to compare potentially impacted to control sites. The concentrations of eleven trace elements (i.e., Al, As, B, Ba, Cd, Cr, Cu, Mn, Pb, Se, and Zn) in Methow River sediments downstream from the abandoned mine sites were higher than background levels. Exposed trout and caddisfly larvae in the Methow River showed reduced growth compared to controls. Samples of liver from juvenile trout and small intestine from exposed caddisfly larvae were examined for evidence of metal accumulation, cytopathological change, and chemical toxicity. Morphological changes ...

2003-05-15

22

Housing and capital accumulation : on the role of taxes

Full Text Available

2008-09-01

23

Norwegian Open Research Archives (NORA)

Full Text Available

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The complexities of skeletal biology

The analysis of biological and environmental samples for lead by photon activation

For a long time, the skeleton was seen as an amorphous tissue of little biological interest. But

2003-01-01

25

Entomopathogenic Nematodes in Biological Control

... activation analysis biological materials bremsstrahlung environment lead lead

26

International Science & Technology Center (ISTC)

Commercial Production and Development, in Entomopathogenic Nematodes in Biological Control

27

Biology and Monitoring of Diamondback Terrapins in the Chesapeake Bay

Interfaces in aquatic ecosystems: Implications for transport and impact of anthropogenic compounds

... to maintaining healthy terrapin populations in the Chesapeake. Biology and Monitoring of Diamondback Terrapins in the Chesapeake ... ...

28

A Radiation Laboratory Curriculum Development at Western Kentucky University

Mechanisms that govern transport, accumulation and toxicity of persistent pollutants at interfaces in aquatic ecosystems were the foci of this thesis. Specific attention was paid to humic substances, their occurrence, composition, and role in exchange processes across interfaces. It was concluded that: The composition of humic substances in aquatic surface microlayers is different from that of the subsurface water and terrestrial humic matter. Levels of dissolved organic carbon (DOC) in the aquatic surface microlayer reflect the DOC levels in the subsurface water. While the levels and enrichment of DOC in the microlayer generally show small variations, the levels and enrichment of particulate organic carbon (POC) vary to a great extent. Similarities exist between aquatic surface films, artificial semi-permeable and biological membranes regarding their structure and functioning. Acidification and liming of freshwater ecosystems affect DOC:POC ...

1996-11-01

29

Validation of biological markers for quantitative risk assessment.

We present the latest developments for the radiation laboratory curriculum at the Department of Physics and Astronomy of Western Kentucky University. During the last decade, the Applied Physics Institute (API) at WKU accumulated various equipment for radiation experimentation. This includes various neutron sources (computer controlled d-t and d-d neutron generators, and isotopic 252 Cf and PuBe sources), the set of gamma sources with various intensities, gamma detectors with various energy resolutions (NaI, BGO, GSO, LaBr and HPGe) and the 2.5-MeV Van de Graaff particle accelerator. XRF and XRD apparatuses are also available for students and members at the API. This equipment is currently used in numerous scientific and teaching activities. Members of the API also developed a set of laboratory activities for undergraduate students taking classes from the physics curriculum (Nuclear Physics, Atomic Physics, and Radiation Biophysics). Our goal is to develop a set of ...

2009-03-10

30

How safe are the biologicals in treating asthma and rhinitis?

The evaluation of biological markers is recognized as necessary to the future of toxicology, epidemiology, and quantitative risk assessment. For biological markers to become widely accepted, their validity...Full Text Available

1991-01-01

31

A number of biological agents are available or being investigated for the treatment of asthma and rhinitis. The safety profiles of these biologic agents, which may modify allergic and immunological...Full Text Available

32

Synthesis and biological evaluation of ABCD ring fragments of the kibdelones.

Earth`s history has been witness to recurrently alternating phases of catastrophic evolution and dominant tectonic deformations, contractions and extension of rifting and spreading leading to quasi-cyclic changes in sedimentary environment and various earth processes. Recent studies have shown quasi-periodicities of 32{+-}2 Million years (Myr) in various endogenic (geomagnetic reversals, magmatic events, mantle convection, various tectonic activities, climate change and biological extinctions) and exogenic (impact catering) processes indicating a remarkable kinship. A time series analysis is presented of the available CO{sub 2} record over the past 250 Myr decoded from global CaCO{sub 3} accumulation rates in sedimentary environment. The time series analysis reveals an intriguing evidence of a dominant periodicity of 33{+-}2 Myr which matches closely with a `common catastrophic periodicity` of 32 Myr identified in various terrestrial and ...

1998-12-31

33

Phorbol esters from croton oil chemical nature and biological activities

PMID:21370327

2011-02-18

34

Demineralization of Crab Shells by Chemical and Biological Treatments

Not Available

1967-01-01

35

Biological Markers as Predictors of Radiosensitivity in Syngeneic Murine Tumors

Full Text Available

2005-02-01

36

University of Central Lancashire - Facilities

Full Text Available

2006-06-01

37

Spectroscopy, colorimetry, and biological chemistry in the nineteenth century.

...specialised laboratories for pharmaceutics, tissue culture and molecular biology Excellent Laboratory Facilities Tissue Culture Facilities Molecular Biology Laboratory ...

38

Biology of the Rio Grande Border Region: A Bibliography

The development of colorimetry and spectroscopy in the nineteenth century is described. An account is given of the application of their techniques to biological chemistry during that period.

1981-03-01

39

Studies of inactivation, retardation and accumulation of viruses in porous media by a combination of dye labeled and native bacteriophage probes

BIOLOGY OF THE RIO GRANDE BORDER REGION: A BIBLIOGRAPHY Information and Technology Report USGS/BRD/ITR--1997- .....

40

Nitrogen accumulation in clays: solid-solution equilibrium and risk of gas generation

Not Available

2011-06-01

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41

Influence of no coincidence of time constants of accumulators in two-channels radiometric defectoscope

No abstract prepared.

2002-07-01

42

Short note.

43

Fuel wood yarder

In vivo and in vitro evaluation of dota-lanreotide radiolabelled with gallium-67

A small cable yarding system for accumulations of slash on forested land and overstocked non-productive stands is described.

1984-01-01

44

Radioactivity in sediments of the Great Lakes: post-depositional redistribution by deposit-feeding organisms

One of the refinements of modern Nuclear Medicine is the capacity of providing dynamic and kinetics images of the administered radiopharmaceutical, reproducing its transport mechanism, action sites, receptor binding and excretion route. With the continues technological advances new radiopharmaceuticals have been developed in order to express higher specificity and with higher characters of affinity between receptor/complex. One radiopharmaceutical is formed by a reagent or bio molecule that has in its structure a radioisotope, that has the objectives of carrying it to the organs of affinity or to benign or malign tumoral process. Somatostatin inhibits the growing and proliferation of several tumoral cells. Somatostatin analogs bind to somatostatic receptors that are expressed in different kind of neoplasia DOTA-LANREOTIDE (DOTALAN) is an octapeptide analog to somatostatin. The interest of labeling the bio conjugate with gallium-67 in Nuclear Medicine comes from its physical, chemical ...

45

Increased Mercury Bioaccumulation Follows Water Quality Improvement

At two locations in southern Lake Huron (U.S.A.), twelve 35.5-cm diameter cores of fine-grained sediments were taken for comparison of the vertical distribution of "2"1"0Pb and fallout "1"3"7Cs with the distribution of benthic macroinvertebrates, mainly oligochaete worms (Tubificidae) and the amphipod, Pontoporeia affinis. Locations were selected on the basis of "2"1"0Pb distributions measured a year earlier which indicated contrasting depths of mixing of surface sediments. At one location the activity of "2"1"0Pb is uniform down to about 6 cm and 95% of total invertebrates occur within this zone; at the other location the zone of constant activity is only 3 cm deep but 90% of the invertebrates occur within it. Comparison of published tubificid defecation rates with sediment accumulation rates based on "2"1"0Pb shows that oligochaetes alone can account for mixing in one case while the effects of amphipods may be required in the case of shallower mixing. If mixing ...

46

Biochemical and ultrastructural processing of ["1"2"5I]epidermal growth factor in rat epidermis and hair follicles: accumulation of nuclear label

Changes in physical and chemical characteristics of aquatic habitats made to reduce or eliminate ecological risks can sometimes have unforeseen consequences. Environmental management activities on the U.S. Dept. of Energy reservation in Oak Ridge, Tennessee,have succeeded in improving water quality in streams impacted by discharges fi-om industrial facilities and waste disposal sites. The diversity and abundance of pollution-sensitive components of the benthic macroinvertebrate communities of three streams improved after new waste treatment systems or remedial actions reduced inputs of various toxic chemicals. Two of the streams were known to be mercury-contaminated from historical spills and waste disposal practices. Waterborne mercury concentrations in the third were typical of uncontaminated systems. In each case, concentrations of mercury in fish, or the apparent biological availability of mercury increased over the period during which ecological metrics ...

47

Biochemical and ultrastructural processing of (/sup 125/I)epidermal growth factor in rat epidermis and hair follicles: accumulation of nuclear label

Although the intracellular ultrastructural processing of epidermal growth factor (EGF) and its receptor have been described in cell culture systems, very few studies have examined this phenomenon in intact tissues. We have examined the ultrastructural and biochemical handling of ["1"2"5I]EGF in the epidermis and hair follicle bulb of intact, viable, 3- to 5-day-old rat skin the EGF receptor distribution of which has already been documented and in which EGF has been shown to be biologically active. After incubation of explants with 10 nM ["1"2"5I]EGF for 2.5 h at 25 degrees or 37 degrees C, radiolabel was detected over the basal cells of the epidermis and hair follicle outer root sheath, confirming previous light microscope observations. More specifically, silver grains were observed near coated and uncoated plasma membrane and coated membrane invaginations, Golgi apparatus, lysosomal structures, and nuclei. Sodium azide inhibited internalization of label, whereas a ...

1987-01-01

48

Underlying Principles of Natural Selection in Network Evolution: Systems Biology Approach

Although the intracellular ultrastructural processing of epidermal growth factor (EGF) and its receptor have been described in cell culture systems, very few studies have examined this phenomenon in intact tissues. We have examined the ultrastructural and biochemical handling of (/sup 125/I)EGF in the epidermis and hair follicle bulb of intact, viable, 3- to 5-day-old rat skin the EGF receptor distribution of which has already been documented and in which EGF has been shown to be biologically active. After incubation of explants with 10 nM (/sup 125/I)EGF for 2.5 h at 25 degrees or 37 degrees C, radiolabel was detected over the basal cells of the epidermis and hair follicle outer root sheath, confirming previous light microscope observations. More specifically, silver grains were observed near coated and uncoated plasma membrane and coated membrane invaginations, Golgi apparatus, lysosomal structures, and nuclei. Sodium azide inhibited internalization of label, ...

1987-03-01

49

Systems biology is a rapidly expanding field that integrates diverse areas of science such as physics, engineering, computer science, mathematics, and biology toward the goal of elucidating the underlying...Full Text Available

50

Research - Keyword Index

Biologic Rhythms Derived from Siberian Mammoths' Hairs

...and biological processes acting on recruitment and post-recruitment EU-Agrinet - Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quality indicator ... Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quali EU-Agrinet - Project sheet: Genetic evaluation of European ...

51

The stability of biological standards

Hair is preserved for millennia in permafrost; it enshrines a record of biologic rhythms and offers a glimpse at chronobiology as it was in extinct animals. Here we compare biologic rhythms gleaned...Full Text Available

52

Suitability of a New Plant Invader as a Target for Biological Control in Florida

The authors emphasize the importance of stability in biological standards and discuss the steps taken to ensure the stability of International Standards and the theoretical basis of the various stability...Full Text Available

1956-01-01

53

Menstrual Cycle: Basic Biology

... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemoniales: Acanthaceae), a suitable target for classical biological ... ...

54

MODELING AND BIOLOGICAL CONTROL OF MOSQUITOES

The basic biology of the menstrual cycle is a complex, coordinated sequence of events involving the hypothalamus, anterior pituitary, ovary, and endometrium. The menstrual cycle with all its...Full Text Available

2008-01-01

55

Liver Carcinogenesis Unit

Models can be useful at many different levels when considering complex issues such as biological control of mosquitoes. At an early stage, exploratory models are valuable in exploring the characteristics...Full Text Available

2007-01-01

56

Kenai Fjords National Park Biological Resources Buffer Coverage

The Liver Carcinogenesis Section uses the modern technologies of molecular biology, cell biology, protein chemistry and genetics to investigate the biochemical and genetic pathways involved in human liver cancer.

57

Healthy aging and disease: role for telomere biology?

... a buffer of all biological resources in the Kenai Fjords National Park Area. Data from Alaska Fish ... ...

58

Genetics, Genomics, and Molecular Biology

Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease,...Full Text Available

2011-05-01

59

Biosphere analyses for the safety assessment SR-Site - synthesis and summary of results

Genetics, Genomics, and Molecular Biology USGS scientists develop and integrate new genetic and molecular techniques into systematic analyses to describe individuals and populations of fish .....

60

Heat Stress and Hormetin-Induced Hormesis in Human Cells: Effects on Aging, Wound Healing, Angiogenesis, and Differentiation

This report summarises nearly 20 biosphere reports and gives a synthesis of the work performed within the SR-Site Biosphere project, i.e. the biosphere part of SR-Site. SR-Site Biosphere provides the main project with dose conversion factors (LDFs), given a unit release rate, for calculation of human doses under different release scenarios, and assesses if a potential release from the repository would have detrimental effects on the environment. The intention of this report is to give sufficient details for an overview of methods, results and major conclusions, with references to the biosphere reports where methods, data and results are presented and discussed in detail. The philosophy of the biosphere assessment was to make estimations of the radiological risk for humans and the environment as realistic as possible, based on the knowledge of present-day conditions at Forsmark and the past and expected future development of the site. This was achieved by using the best available ...

2010-12-15

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Enzymatic control of anhydrobiosis-related accumulation of trehalose in the sleeping chironomid, Polypedilum vanderplanki

Accumulation of molecular damage and increased molecular heterogeneity are hallmarks of cellular aging. Mild stress-induced hormesis can be an effective way for reducing the accumulation of molecular...Full Text Available

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Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant

Larvae of an anhydrobiotic insect, Polypedilum vanderplanki, accumulate very large amounts of trehalose as a compatible solute on desiccation, but the molecular mechanisms underlying...Full Text Available

2010-10-01

63

Biosynthesis, Translocation, and Accumulation of Betaine in Sugar Beet and Its Progenitors in Relation to Salinity 12

BackgroundInterest in lycopene metabolism and regulation is growing rapidly because accumulative studies have suggested an important role for lycopene in human health promotion....Full Text Available

64

Studies about oxygen accumulation in palladium silicide formed at Pd/a-Si interface

Like other halophytic chenopods, sugar beet (Beta vulgaris L.) can accumulate high betaine levels in shoots and roots. N,N,N-trimethylglycine impedes sucrose crystallization...Full Text Available

1982-10-01

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Effect of Irrigation Water Salinization on Salt Accumulation of Plastic Film House Soil around Sumjin River Estuary

... 194 p. auger electron spectroscopy decomposition deposition interfaces oxygen

1986-04-23

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Design guidelines to prevent the accumulation of radiolysis gases in BWR steam piping

Full Text Available

2008-12-01

67

Calculation of ice accumulation rates in Antarctica over the last glacial cycle.

... Power Company, Tokyo (Japan) Ishida, T. Japan Atomic Power Company,

2007-02-01

68

Environmental Research Database

DescriptionRates of ice accumulation in Antarctica are not known well, yet they are fundamental to assessing the ice sheet mass balance. Past accumulation rates are less well defined. We are in a unique position to provide detailed accounts of accumulation in Antarctica. We will measure isochronous internal layering across the ice sheet, which can be readily identified in radar data that we hold. Internal layers will be traced to ice-cores (allowing dating) and across wide regions of the ice sheets. A nume [continued...

2006-01-08

69

Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity.

DEFF Research Database (Denmark)

Udgivelsesdato: 2007-Feb

2007-01-01

70

Synthetic Biology and Human Health: Potential Applications for Spaceflight

Space Biology and Medicine

Human space travelers experience a unique environment that affects homeostasis and physiologic

2011-01-01

71

Radon concentration measurements in a radon chamber for biological treatment using track detectors

Volume IV is devoted to examining the medical and associated organizational measures used to

2004-01-01

72

Radiation Protection of the Organism (Selected Chapters)

Short communication.

1992-09-01

73

Novel Antidrugabuse Peptide

... biologically important compounds is sharply lowered with passage of the solutions to the cell an organ, where their sensitivity ...

1970-12-11

74

International Science & Technology Center (ISTC)

Natural Biologically Active HLDF6 Peptide as Potential Preparation for Correction of Different Drugabuse Forms

75

Mechanism of superoxide anion-radical reactions with some biologically important compounds in aqueous solutions

Mechanical-biological waste treatment as an alternative to thermal processes; MBA-Konzepte als Alternative zur thermischen Abfallbehandlung

Short note.

1989-08-21

76

Localization of "2"0"3Pb-chloride in myocardial infarction

No abstract prepared.

2001-09-01

77

Lead-203 for skeletal imaging

... AND NUCLEAR MEDICINE biological localization cardiovascular diseases

78

Internalization of cholera toxin by different endocytic mechanisms

... biological variability body distribution kidneys labelled compounds lead 203

79

DEFF Research Database (Denmark)

Cell biology, clathrin, endocytosis, dynamin, caveolae, cholera toxin

2001-01-01

80

Illuminating Cell Biology

Fresh-water biology, by Henry Baldwin Ward ... and George Chandler Whipple ... with the collaboration of a staff of ...

NASA's Ames Research Center awarded Ciencia, Inc., a Small Business Innovation Research contract to

2002-01-01

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81

European Society for Evolutionary Biology meeting. Tracing the common roots of antibiotic resistance.

Language: English ...

82

Determination of Shooting Distance from Deformation of the ...

PMID:21921169

2011-09-16

83

Chemical and biological aspects of an arabinogalactan from the medicinal herb Phyllanthus niruri (quebra-pedra)

... Descriptors : *TERMINAL BALLISTICS, *WOUND BALLISTICS, VELOCITY, CONVERSION, REPRINTS, TISSUES(BIOLOGY), MANUFACTURING ...

84

Biophotonics and Bone Biology

No abstract prepared.

2005-07-01

85

Biology-inspired Architecture for Situation Management

One of the more-serious side effects of extended space flight is an accelerated bone loss

2004-01-01

86

Biology of lichen communities in Antarctica.

Situation Management is a rapidly developing science combining new techniques for data collection

2006-01-01

87

Biology and The Future of Mars

-Ecophysiological and floristic study of the lichen communities in .... Plasticity of the Lichen Catillaria corymbosa in Different Microhabitats of the ...

88

Biological Control of Sclerotinia sclerotiorum Using Indigenous Chitinolytic Actinomycetes in Jordan

It is possible that at some time in the future we might recreate a habitable climate on Mars

2004-01-01

89

Detection of recurrence and the effect of transcatheter hepatic arterial embolization using lipiodol (Lp-TAE) assessed by the lipiodol accumulative pattern on CT

Full Text Available

2006-06-01

90

[Fundamental biological model for trials of wound ballistics].

We evaluated the relation between the lipiodol accumulative pattern on CT 1 month after 1st Lp-TAE and the effect of Lp-TAE and recurrence of hepatocellular carcinoma (HCC) in 70 cases undergoing Lp-TAE twice. The lipiodol accumulative pattern on CT can be classified into four types (I: homogeneous, II: defect, III: inhomogeneous, IV: no or slight). In the type I, recurrence of the main tumor was 26.7%, daughter was 73.7%, suggesting a good effect of Lp-TAE. In the types II, III and IV, recurrence of the main tumor was seen in 66.7%, 83.3% and 83.3%, respectively, suggesting that the effect of Lp-TAE was worse according to the lipiodol accumulative pattern on CT. The lipiodol accumulative pattern on CT is useful for the detection of recurrence and assessment of the effect of Lp-TAE. (author).

1993-08-01

91

Intestinal accumulation of lead salts and milk lead by suckling rats

The aim of our experiment was the testing of effects of common ammunition on usable and slightly accessible biological tissue thereby to create fundamental simple biological model for trials of wounded ballistic. Like objective tissue was elected biological material - pork and beef hind-limbs, pork head, pork bodily cavity. It was discovered that objective tissue is able to react to singles types of shots in all spectrum results namely simple smooth penetration wound as well as splintery fracture in dependence on kind of using ammunition. Pork hind-limb was evaluated like the most suitable biological material for given object. PMID:17172163

2006-10-01

92

The strong associations between organism characteristics and network architecture

Absorption of lead is known to be enhanced during infancy. In this study, the sites of intestinal accumulation of Pb by suckling rats have been determined under various conditions using "2"0"3Pb as a tracer. When "2"0"3Pb was administered intragastrically (IG) as a soluble salt, accumulation occurred primarily in the duodenum, regardless of dose and vehicle. In contrast, when rat pups suckled from a dam which had received "2"0"3Pb, the only region of the small intestine showing accumulation of radioactivity was the ileum. To confirm that these differences were not related to the route of administration, rat milk was labeled with "2"0"3Pb and was then used for IG administration. Once again, accumulation (4 hr post-administration) was confined to the ileum. When the dose was increased 10-fold, milk Pb displayed some accumulation in duodenal tissue, but very much less than that of ...

93

CERN Document Server

Understanding the dependence and interplay between architecture and function in biological networks has great relevance to disease progression, biological fabrication and biological systems in general. Recent research in complex systems and networks, presents methods to properly mine the architectural interdependence in networks. Guided by such work, we propose methods to associate organism characteristics with network topology by analyzing a large number of architectural patterns. We adopt an automated approach using 11 topological metrics from complex networks to characterize a collection of various kinds of biological networks. Principal component analysis and clustering allow us to extract the indispensable, independent and informative metrics. Using hierarchical linear modeling, we observe that organism characteristics associate with these metrics, surprisingly well. This work can serve as a ...

2009-01-01

94

Dynamic neuronal ensembles: Issues in representing structure change in object-oriented, biologically-based brain models

Progress on the investigation of coal-water-slurry fuel combustion in a medium-speed diesel engine; Part 3-accumulator injector performance

This paper describes the structure of dynamic neuronal ensembles (DNEs). DNEs represent a new paradigm for learning, based on biological neural networks that use variable structures. We present a computational neural element that demonstrates biological neuron functionality such as neurotransmitter feedback absolute refractory period and multiple output potentials. More specifically, we will develop a network of neural elements that have the ability to dynamically strengthen, weaken, add and remove interconnections. We demonstrate that the DNE is capable of performing dynamic modifications to neuron connections and exhibiting biological neuron functionality. In addition to its applications for learning, DNEs provide an excellent environment for testing and analysis of biological neural systems. An example of habituation and hyper-sensitization in biological systems, using a neural ...

1996-12-31

95

The Importance of Mitochondrial DNA in Aging and Cancer

Coal-water-slurry (CWS) engine tests designed to evaluate a new accumulator-based injection system are described in this paper The new injection system was found to improve CWS burnout considerably at both full and part engine loads. The peak cylinder firing pressure when operating with CWS was no higher than when operating with diesel oil. These data demonstrates the improved engine performance that can be achieved with the accumulator-based injection system.

1989-07-01

96

Studies about oxygen accumulation in palladium silicide formed at Pd/a-Si interface

Mitochondrial dysfunction has been implicated in premature aging, age-related diseases, and tumor initiation and progression. Alterations of the mitochondrial genome accumulate both in aging tissue...Full Text Available

97

Protein misfolding disorders and macroautophagy

Portuguese 1986. p. 186. Brazil Achete, CA Rio de Janeiro Univ. (Brazil).

1986-04-23

98

Pesticide-induced immunotoxicity: are Great Lakes residents at risk?

A large group of diseases, termed protein misfolding disorders, share the common feature of the accumulation of misfolded proteins. The possibility of a common mechanism underlying either the pathogenesis...Full Text Available

2011-04-01

99

NASA/Marshall Space Flight Center Cooperative Education Program

Several organophosphate and organochlorine compounds, including pesticides commonly found in the Great Lakes basin, have the potential to induce immunotoxicity. Because of biomagnification and accumulation...Full Text Available

1995-12-01

100

NASA's Strategic Human Capital Implementation Plan - NASA Headquarters

Co-op students hired since December 3, 1983 will be covered under FERS. ... amount of sick leave that can be accumulated for use in succeeding years. 11. ...

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101

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD

o If retaining CSRS/FERS, transferred employee will be credited with accumulated sick leave o Be reimbursed for travel, transportation, relocation costs ...

102

Genomic view of the evolution of the complement system

While the etiology of Parkinson's disease remains largely elusive, there is accumulating evidence suggesting that mitochondrial dysfunction occurs prior to the onset of symptoms in Parkinson's disease....Full Text Available

103

Effects of cultivar and culture conditions on g-aminobutyric acid accumulation in germinated fava beans (Vicia faba L.)

The recent accumulation of genomic information of many representative animals has made it possible to trace the evolution of the complement system based on the presence or absence of each complement...Full Text Available

2006-09-01

104

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND: High levels of g-aminobutyric acid (GABA) accumulate in plant tissues under various stresses. GABA accumulation is also influenced by cultivar. This aim of this study was to select the most promising cultivar of fava bean for GABA accumulation and to optimise the culture conditions for GABA production in germinated fava beans by response surface methodology based on central composite design (CCD). RESULTS: GABA content and glutamate decarboxylase activity in germinated seeds of cultivar S2 were significantly higher than those in other cultivars (P < 0.05). A significant negative correlation (r = -0.765, P < 0.05) between germination percentage and 1000-kernel weight was observed. There was a linear relationship between GABA content and sprout length (R2 = 0.816). The regression...

2010-01-01

105

Biodynamic modelling of the accumulation of Ag, Cd and Zn by the deposit-feeding polychaete Nereis diversicolor: Inter-population variability and a generalised predictive model

British Library Electronic Table of Contents (United Kingdom)

Biodynamic parameters of the ragworm Nereis diversicolor from southern Spain and south England were experimentally derived to assess the inter-population variability of physiological parameters of the bioaccumulation of Ag, Cd and Zn from water and sediment. Although there were some limited variations, these were not consistent with the local metal bioavailability nor with temperature changes. Incorporating the biodynamic parameters into a defined biodynamic model, confirmed that sediment is the predominant source of Cd and Zn accumulated by the worms, accounting in each case for 99% of the overall accumulated metals, whereas the contribution of dissolved Ag to the total accumulated by the worm increased from about 27 to about 53% with increasing dissolved Ag concentration. Standardised va...

2010-01-01

106

BIG BEAR SOLAR OBSERVATORY - NASA Technical Report Server (NTRS)

Approaches to the evaluation of chemical-induced immunotoxicity.

replacing the KDP crystal, and introducing computer programs for accumulation of an almost unlimited number of frames. The calibration procedure using solar ...

107

The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens

The immune system plays a crucial role in maintaining health; however, accumulating evidence indicates that this system can be the target for immunotoxic effects caused by a variety of chemicals including...Full Text Available

1995-12-01

108

Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs)

BackgroundPCR amplification for the detection of pathogens in biological material is generally considered a rapid and informative diagnostic technique. Invasive Salmonella...Full Text Available

109

Reproductive Success of Cavity-nesting Birds Breeding under High-voltage Powerlines

Early on, intriguing biological activities were found associated with the EETs using in vitro systems. Although the EETs other than the 5,6-isomer, are quite stable chemically,...Full Text Available

2007-01-01

110

Preparation and biological properties of a novel composite scaffold of nano-hydroxyapatite/chitosan/carboxymethyl cellulose for bone tissue engineering

... biological effects of electromagnetic fields (EMFs) produced by high-voltage transmission lines have come under intense scrutiny, mostly with respect ... biological effects of electromagnetic fields (EMFs...

111

Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.

In this study, we report the physico-chemical and biological properties of a novel biodegradable composite scaffold made of nano-hydroxyapatite and natural derived polymers of chitosan and carboxymethyl...Full Text Available

112

Near Infrared Dyes as Lifetime Solvatochromic Probes for Micropolarity Measurements of Biological Systems

Cleavage of membrane-associated proteins with the release of biologically active macromolecules is an emerging theme in biology. However, little is known about the nature and regulation of the involved...Full Text Available

1996-07-23

113

Metabolic clearance of biologically active luteinizing hormone in man.

The polarity of biological mediums controls a host of physiological processes such as digestion, signaling, transportation, metabolism, and excretion. With the recent widespread use of near-infrared...Full Text Available

2007-10-15

114

Estimation of effective population sizes from data on genetic markers

The plasma metabolic clearance of biologically active luteinizing hormone (bioactive LH) was studied using the rat interstitial cell testosterone (RICT) bioassay in six hypogonadotropic men after single...Full Text Available

1986-04-01

115

Electron spin resonance studies of radiation effects in biological materials. An assessment of current and future research

The effective population size (N_e) is an important parameter in ecology, evolutionary biology and conservation biology. It is, however, notoriously difficult to estimate,...Full Text Available

2005-07-29

116

Effects of Collaborative Group Composition and Inquiry Instruction on Reasoning Gains and Achievement in Undergraduate Biology

Electron spin resonance spectroscopy can provide a powerful approach to the study of radiation effects in biological materials. This memorandum gives an overview of current and future research. (author).

1987-06-01

117

Effects of 3 biologic dressings on healing of cutaneous wounds on the limbs of horses

This study compared the effectiveness of collaborative group composition and instructional method on reasoning gains and achievement in college biology. Based on initial student reasoning ability (i.e.,...Full Text Available

2011-03-01

118

Core Synthesis Facility: Bridging the Gap between Chemistry and Biology

AbstractThree biologic dressings [split-thickness allogeneic skin (STS)], allogeneic peritoneum (P), and xenogenic porcine small intestinal submucosa (PSIS)] were...Full Text Available

2004-01-01

119

Coordination chemistry and biological activity of 5'-OH modified quinoline-B12 derivatives.

CF-23“The biggest stumbling block for biological sciences turned out to be synthetic organic chemistry” – Elias A. Zerhouni, Former NIH Director in Chemical...Full Text Available

2010-09-01

120

Computational approaches to discovering semantics in molecular biology

The consequences of structural modifications at the 5'-OH ribofuranotide moiety of quinoline modified B12 derivatives are discussed in regard of the coordination chemistry, the electrochemical properties and the biological behaviour of the compound. PMID:21850334

2011-08-18

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121

C. elegans as a model for stem cell biology

One of the central questions of molecular biology is the discovery of the semantics of DNA. This discovery relies in a critical way on a variety of expensive computations. In order to solve these computations, both parallel computers and special-purpose hardware play a major role.

1989-07-01

122

Biologically based pesticide dose estimates for children in an agricultural community.

We review the application of C. elegans as a model system to understand key aspects of stem cell biology. The only bona fide stem cells in C. elegans...Full Text Available

2010-05-01

123

Biological species is the only possible form of existence for higher organisms: the evolutionary meaning of sexual reproduction

Current pesticide health risk assessments in the United States require the characterization of aggregate exposure and cumulative risk in the setting of food tolerances. Biologic monitoring can aggregate...Full Text Available

2000-06-01

124

BFL: a node and edge betweenness based fast layout algorithm for large scale networks

Consistent holistic view of sexual species as the highest form of biological existence is presented. The Weismann's idea that sex and recombination provide the variation for the natural...Full Text Available

125

An Undergraduate Course to Bridge the Gap between Textbooks and Scientific Research

BackgroundNetwork visualization would serve as a useful first step for analysis. However, current graph layout algorithms for biological pathways are insensitive to biologically...Full Text Available

126

A Floristic Reconnaissance of Montane Environments in the Foja Mts. of Papua Province, Indonesia

This article reports on a one-semester Advanced Cell Biology course that endeavors to bridge the gap between gaining basic textbook knowledge about cell biology and learning to think and work as a researcher....Full Text Available

2011-03-01

127

Genomics - from Neanderthals to high-throughput sequencing

... A Rapid Biological Assessment of the Kaijende Highlands, Enga Province, Papua New Guinea. RAP Bulletin of Biological ... A Rapid Biodiversity Assessment of the Kaijende Highlands, Enga Province, Papua New...

128

Genetic Applications in Avian Conservation

A report on 'The Biology of Genomes' meeting, Cold Spring Harbor, USA, 10-14 May 2006.

2006-01-01

129

Effect of dietary constituents on the absorption of lead in the human

... structure along an elevational gradient in Hawaiian honeycreepers reveals contrasting evolutionary responses to avian malaria. BMC Evolutionary Biology 8: ... ...

130

Development of a motion analysis system using acceleration sensors for tennis and its evaluations

... biological effects body burden diet intestinal absorption lead lead 203 man

1983-03-01

131

British Library Electronic Table of Contents (United Kingdom)

The term biological motion is often used by researchers studying the patterns of movement generated by living forms and in sports. We studied a pattern recognition system of motion in sport using biological motion data. Biological motion data are acquired using a 3D motion capture system. However, 3D motion capture systems are very expensive. In this article, a biological motion capture system was built using acceleration sensors. Our proposed system uses the technique of Gaussian fitting and regression analysis. We tested our proposed system in pattern recognition of outdoor tennis and its evaluations.

2011-01-01

132

Comparison of Microbial Fungicides in Antagonistic Activities Related to the Biological Control of Phytophthora Blight in Chili Pepper Caused by Phytophthora capsici

Biology-Inspired Distributed Consensus in Massively-Deployed Sensor Networks

Full Text Available

2010-12-01

133

BIOMAGNETIC RESPONSE OF SIMPLE BIOLOGICAL ...

Promises of ubiquitous control of the physical environment by large-scale wireless sensor networks

2005-01-01

134

The loss of lead in biological materials following different drying and ashing procedures

... Examples include magnetic forming tools, magnetic shielding, magnetohydrodynamic propulsion systems, and various magnetic containment ...

1970-01-01

135

Physical mechanisms of biological molecular motors

The loss of lead in various kinds of biological materials after drying and ashing is studied by using "2"0"3Pb as tracer which is intravenously injected into mice. The experimental results show that although the oven ashing can be used for determining the lead in samples of lung, kidney, and liver, etc., the oxygen plasma and high pressure digestion are the most suitable methods for the determination of lead in biological materials. (author) 5 refs.; 2 tabs.

136

Neutrons in Biology. A satellite meeting of the IUPAB/EBSA biophysics congress

Biological motors generally fall into two categories: (1) those that convert chemical into mechanical energy via hydrolysis of a nucleoside triphosphate, usually adenosine triphosphate, regarded as life's chemical currency of energy and (2) membrane bound motors driven directly by an ion gradient and/or membrane potential. Here we argue that electrostatic interactions play a vital role for both types of motors and, therefore, the tools of physics can greatly contribute to understanding biological motors.

2009-03-01

137

Biological network analysis and comparison: mining new biological knowledge

This meeting focussed on the study of the structure and dynamics of biological molecules, with particular emphasis on neutron and complementary methods as well as related enabling technologies. The program covered biological problems that are being addressed by neutron scattering and those where there is the potential to do so in the future. This document provides the abstracts of the different presentations. (A.L.B.)

2005-07-01

138

British Library Electronic Table of Contents (United Kingdom)

The mechanisms underlying life machinery are still not completely understood. Something is known, something is ?probably? known, other things are still unknown. Scientists all over the world are working very hard to clarify the processes regulating the cell life cycle and bioinformaticians try to support them by developing specialized automated tools. Within the plethora of applications devoted to the study of life mechanisms, tools for the analysis and comparison of biological networks are catching the attention of many researchers. It is interesting to investigate why.

2011-01-01

139

Biological effects of electromagnetic radiation in the microwave range

Root-to-shoot Cd translocation via the xylem is the major process determining shoot and grain cadmium accumulation in rice

The book examines current experimental and clinical knowledge concerning the biological and biophysical effects of electromagnetic radiation, particularly that in the microwave range. The biophysical bases of the interaction of electromagnetic radiation with matter are reviewed with emphasis on biological systems, and the effects of radiation on critical biological systems, including the nervous, reproductive, visual and blood-forming systems are compared. Data concerning the lethal effects of nonionizing radiation is presented and characteristics of the effects of electromagnetic radiation on the whole mammalian organisms are examined. Various reactions of the neuroendocrine system to electromagnetic radiation are described, with particular attention given to the adrenal system, and the combined effects of ionizing and microwave radiation in the flight environment are discussed. Results are also presented of a series of ...

1980-01-01

140

Modelling the spatial and temporal evolution of winter glacier mass balance.

Physiological properties involved in divergent cadmium (Cd) accumulation among rice genotypes were characterized using the indica cultivar ‘Habataki’ (high Cd in grains)...Full Text Available

2009-07-01

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141

Environmental Research Database

DescriptionChanges in glacier mass balance are critically influenced by the distribution of snow accumulation at the start of the melt season, but models of the winter season lag seriously behind those of the melt season. The overall aim is to test physically-based models of the spatial and temporal evolution of the winter snowpack at a temperate ice cap (Langjokull, Iceland), to assess how effectively and also how efficiently they capture variation in winter accumulation. A three-step modelling approach i [continued...

2004-01-31

142

Dispersed alkali elements in minerals and products of natural salts processing

Enhanced cadmium cytotoxicity in A549 cells with reduced glutathione levels is due to neither enhanced cadmium accumulation nor reduced metallothionein synthesis

Distribution of scattered elements in basic minerals of salt-rocks is studied. It is shown that rubidium and cesium are accumulated mainly in carnallites and are contained in small quantities halites. These elements are accumulated primarily in the carnallite production products, wherein their content in a number of cases exceeds by dozens and hundred times their content in source rocks. It is noted that only carnallites may be considered in the list of actual sources for rubidium and cesium separation

1995-06-01

143

Dislocation accumulation at large plastic strains -- An approach to the theoretical strength of materials

Glutathione (GSH) depletion sensitizes human lung carcinoma (A549-T27) cells to the cytotoxic effects of Cd++. The effects of GSH depletion on Cd++ accumulation and Cd++-induced metallothionein (MT) content were investigated to determine the possible role of these Cd++ responses in the sensitization process. Cellular GSH was depleted to 20% to 25% of control levels with buthionine sulfoximine (BSO), or diethyl maleate (DEM), respectively. Neither treatment significantly affected Cd++-induced accumulation of exogenous 35s-cysteine into intracellular MT in a dose-dependent fashion. The results indicate that neither enhanced Cd++ accumulation nor reduced MT synthesis plays a primary role in affecting enhanced Cd++ cytotoxicity in A549 cells with reduced GSH levels. Although BSO inhibition of GSH synthesis enhanced MT synthesis, it sensitized the cells to Cd++, which suggests an additive effect of GSH and MT in cadmium ...

144

Migration of strontium in the food chain of plants, animals and man - problems and risks

The usual method of introducing engineers to the concept of dislocations and their role in plastic flow is to compare an estimate of the theoretical strength of solid (of order {micro}/30 where {micro} is the shear modulus) and the observed strength of either single crystals ({mu}/10{sup 4}) or practical engineering material such as structural steels where the yield stress in shear is of order {mu}/10{sup 3}. However, if one considers the problem in reverse, one can consider the accumulation of dislocations as an important mechanism by which one can produce engineering materials in which the strength level approaches the theoretical strength. If one assumes that the flow stress can be expressed in terms of te mean free path between stored dislocations or as the square root of the global dislocation density, then one can see the influence of dislocation density in a diagrammatic form. It is clear that the strengthening by dislocation ...

1999-04-01

145

Sulfation of chitosan oligomers enhances their anti-adipogenic effect in 3T3-L1 adipocytes

The aims of investigation were to follow the Sr transport in the food chain from the flora to the fauna and humans, and its dependence on the geological origin og the plant site, industrial emissions, the age and site of plants, the part of plant used for nutrition and the strontium content in the drinking water, to determine the Sr intake of humans with the help of the duplicate method, and to estimate the apparent absorption rate and balance of strontium depending on of the form of diet (mixed or ovolactovegetarian), sex, season, age, region (geological origin of the living space) and method of intake measurement (duplicate or basket method). Strontium, an ultra trace element widespread in the earth's crust, is not essential and only mildly toxic for plants, animals and man according to current knowledge. The biological essentiality of Sr has not been investigated yet. Amoeba species living in sea water use Sr for the formation of their skeleton instead of Ca. ...

2008-10-15

146

British Library Electronic Table of Contents (United Kingdom)

Inhibition of adipogenesis and lipid accumulation has a very crucial role to prevent obesity. Low molecular weight (LMW) chitosan is known to inhibit fat accumulation and adipogenesis. (N,O)-sulfated chitosan is a sulfation derivative of chitosan oligomers, and its anti-obesity effect is not yet reported. In this study, it has been reported that (N,O)-sulfated chitosan significantly decreased lipid accumulation, an indicator for adipogenesis, in differentiating 3T3-L1 preadipocyte cells. Furthermore, mRNA expressions and protein levels of key adipogenic markers such as peroxisome prolifetor-activated receptor (PPAR)-@c and CCAAT-enhancer binding protein (C/EBP)-@a were considerably decreased by (N,O)-sulfated chitosan treatment. As a consequence, sulfation of LMWC remarkably increased its ...

2011-01-01

147

Sucrose accumulation in mature sweet melon fruits. [Cucumis melo

Metabolic engineering of carotenoid accumulation by creating a metabolic sink

Mesocarp tissue from sucrose-accumulating sweet melon (Cucumis melo cv. Galia) showed sucrose synthase activity (ca 1 nkat/gfw) while soluble acid invertase and sucrose phosphate synthase activities were not observed. Sucrose uptake into mesocarp discs was linear with sucrose concentration (1-500 mM) and unaffected by PCMBS and CCCP. Sucrose compartmentation into the vacuole also increased linearly with sucrose concentration as indicated by compartmental efflux kinetics. Mesocarp discs incubated in /sup 14/C-fructose + UDP-glu synthesized /sup 14/C-sucrose and efflux kinetics indicated that the /sup 14/C-sucrose was compartmentalized. These data support the hypothesis that two mechanisms are involved in sucrose accumulation in sweet melon: (1) compartmentation of intact sucrose and (2) synthesis of sucrose via sucrose synthase and subsequent compartmentation in the vacuole.

1987-04-01

148

British Library Electronic Table of Contents (United Kingdom)

Carotenoids are highly beneficial for human nutrition and health because they provide essential nutrients and important antioxidants in our diets. However, many food crops, especially the major staple crops contain only trace to low amounts of carotenoids. Although significant progress has been made in developing food crops rich in carotenoids by altering the expression of carotenoid biosynthetic genes, in many cases it has proved to be difficult to reach the desired levels of carotenoid enrichment. The recent identification and characterization of a novel gene mutation in cauliflower reveals that creating a metabolic sink to sequester carotenoids is an important mechanism to control carotenoid accumulation in plants. The successful demonstration of increased carotenoid accumulation in ass...

2007-01-01

149

Environmental protection, environmental pollution, and economic growth. A contribution to environmental economy in the framework of neoclassic models of growth. Umweltschutz, Umweltverschmutzung und Wirtschaftswachstum. Ein Beitrag zur Umweltoekonomie im Rahmen neoklassischer Wachstumsmodelle

Comparative biochemistry of betaine biosynthesis and accumulation in diverse dicot families

This book is mainly a comparison of the cost of pollution with the cost of environmental protection. As to the causes of pollution, a difference is made between pollutants that accumulate and pollutants that do not accumulate. Because of pollutant accumulation it is necessary to carry out both subsequent pollution abatement measures and to take preventive action which helps to avoid pollutant emission. Growth models serve to substantiate why such preventive action is both ecologically and economically useful as a rule. Finally the study makes a comparison between some tools of environmental protection. It stresses in particular that, if a duty on emissions is levied, the polluter has to bear all the cost of the pollution, while at the same time the quality of the environment can be more successfully improved than by emission standards alone.

1986-01-01

150

Characteristics of the flow-controlled accumulator

Salt stress elicits betaine accumulation to high levels in species from several diverse dicot families (Chenopodiaceae, Amaranthaceae, Convolvulaceae, Solanaceae, and Asteraceae). FAM-MS studies with deuterated precursors showed that species from all these families synthesize betaine from choline. Enzyme assays and immunotitration data showed that all accumulating species contained betaine aldehyde dehydrogenase (BADH) enzyme activity recognized by antibodies raised against purified BADH isolated from Spinacia oleracea. Immunoblotting indicated that the BADH monomer was in all cases of Mr {approx} 63,000. The similarity of BADH in the different species is consistent with a single evolutionary origin for the betaine pathway. This was supported by the presence in immunoblots of a cross-reacting band at Mr {approx} 63,000 in Magnolia x Soulangiana, a primitive angiosperm.

1989-04-01

151

Accumulation of glycosaminoglycans in radiation-induced muscular fibrosis

Mitsubishi is developing a new type of accumulator incorporating the technology of fluidics as one of the seeds for the improved safety of the newly constructed pressurized water reactor plants. This accumulator employs a vortex flow control device, called a vortex damper, as a fluidic device to simplify the safety systems. A fundamental experimental study with a one-fifth scale model and confirmation tests with a one-third scale model to develop the vortex damper have been carried out, and satisfactory results have been achieved. The results of the confirmation tests under the prototype pressure conditions agree well with the basic tests. The flow rate ratio can be 5 to 6. The pressure loss coefficient in the large flow rate period is 8. A cavitation factor is the main parameter of the flow rate coefficient.

152

BMFT. The 'biotechnology 2000' project. Annual report 1991. BMFT. Programm Biotechnologie 2000. Jahresbericht 1991

The content and biosynthesis of glycosaminoglycans (GAGs) were studied in pig thigh muscle after acute local {gamma}-irradiation. Seven months following irradiation, the muscular tissue next to the irradiation cone was replaced by severe mutilating fibrosis delimited by an intermediary perifibrotic zone. Results showed a parallel increase of collagen and GAG content in perifibrotic and fibrotic tissues. Sulphated GAGs, heparan sulphate and dermatan sulphate were preferentially accumulated in fibrotic tissue, while the hyaluronic acid content increased only slightly. Synthesis of sulphated GAGs was more elevated in fibrotic tissue than in perifibrotic zone as compared with normal muscle. Seven months after irradiation well-developed fibrotic tissue continued to synthesize and to accumulate extracellular matrix macromolecules. (Author).

1992-05-01

153

Yeast as a Model System to Study Tau Biology

The ''biotechnology 2000'' project is supervised by the project sponsor ''biology, energy, ecology'' at Forschungszentrum Juelich on behalf of the Federal Ministry for Research and Technology. The project activities cover the development of techniques and methods, cell biology, gene structure and gene regulation, photosynthetic production processes, biological hydrogen production, synthetic biology, protein design, neurobiological research, biosystems, plant breeding, phytomedicine and plant protection, the biology of waste disposal methods, research into methods which replace animal experiments, biological safety research, technology risk assessment, and ethical aspects. A general survey introduces the promoted projects, and standardized data sheets briefly introduce the individual ...

1992-01-01

154

Structure, reactivity, and biological properties of hidantoines; Estrutura, reatividade e propriedades biologicas de hidantoinas

Hyperphosphorylated and aggregated human protein tau constitutes a hallmark of a multitude of neurodegenerative diseases called tauopathies, exemplified by Alzheimer's disease. In spite of an enormous amount of research performed on tau biology, several crucial questions concerning the mechanisms of tau toxicity remain unanswered. In this paper we will highlight some of the processes involved in tau biology and pathology, focusing on tau phosphorylation and the interplay with oxidative stress. In addition, we will introduce the development of a human tau-expressing yeast model, and discuss some crucial results obtained in this model, highlighting its potential in the elucidation of cellular processes leading to tau toxicity.

2011-04-06

155

On vortices heating biological excitable media

Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds. Some biological activities (antimicrobial, anticonvulsant, schistosomicidal) are attributed to the chemical reactivity and consequent affinity of hydantoinic rings towards biomacromolecules. Therefore, knowledge about the chemistry of hydantoins has increased enormously. In this review, we present important aspects such as reactivity of hydantoins, acidity of hydantoins, spectroscopy and crystallographic properties, and biological activities of hydantoin and its derivatives. (author)

2008-07-01

156

Confocal Imaging of Biological Tissues Using Second Harmonic Generation

An extension of the Hodgkin-Huxley mathematical model for the propagation of nerve signal which takes into account dynamical heat transfer in biological tissue is derived and fine tuned with existing experimental data. The medium is heated by Joule's effect associated with action potential propagation, leading to characteristic thermal patterns in association with spiral and scroll waves. The introduction of heat transfer-necessary on physical grounds-provides a novel way to directly observe the movement, regular or chaotic, of the tip of spiral waves in numerical simulations and possibly in experiments regarding different biological excitable media.

2009-11-30

157

Advances in molecular biology: impact on rotavirus vaccine development.

A confocal microscopy imaging system was devised to selectively detect Second harmonic signals generated by biological tissues. Several types of biological tissues were examined using this imaging system, including human teeth, bovine blood vessels, and chicken skin. All these tissues generated strong second harmonic signals. There is considerable evidence that the source of these signals in tissue is collagen. Collagen, the predominant component of most tissues, is known to have second order nonlinear susceptibility. This technique may have diagnostic usefulness in pathophysiological conditions characterized by changes in collagen structure including malignant transformation of nevi, progression of diabetic complications, and abnormalities in wound healing.

2000-03-06

158

Unearthing the Phylogenetic Roots of Sleep

The first candidate rotavirus vaccine was a live attenuated oral vaccine made by the classical empirical method of serial passage of virus in tissue culture cells. Current tetravalent vaccine candidates that are in the final stages of efficacy testing in the United States were made by genetic reassortment. This article briefly highlights how advances in the basic understanding of the molecular biology of rotaviruses have facilitated vaccine development. New approaches for second-generation vaccines and improvements in vaccine efficacy based on further exploitation of the tools and knowledge of rotavirus molecular biology and pathogenesis are discussed. PMID:8752289

1996-09-01

159

Towards a more functional concept of causality in cancer research

Why we sleep remains one of the enduring unanswered questions in biology. At its core, sleep can be defined behaviorally as a homeostatically regulated state of reduced movement and sensory...Full Text Available

2008-08-05

160

The biology of lichen communities in Livingston Island ... - NASA

Advances in molecular technologies challenge the different concepts of causality in biology, epidemiology and multistage mathematical models. The lack of integration of the different aspects of causality...Full Text Available

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161

The biological aspects and behaviour of Heliothis virescens Fabricius adults from irradiated diapausal pupae

-Evaluacion de la fotosintesis y respiracion de especies de macroliquenes significativas en la tundra antartica. -Estudio de las isoenzimas en liquenes ...

162

The Structure of Plant Cell Walls

... bollworm fertility gamma radiation genetic radiation effects life span mating

1974-07-22

163

The Shifty Nature of Grains

The molecular structure, chemical properties, and biological function of the xyloglucan polysaccharide isolated from cell walls of suspension-cultured sycamore (Acer pseudoplatanus)...Full Text Available

1973-01-01

164

The International Reference Preparation of Erythropoietin*

... Astronomy & Space Biology Chemistry & Materials Computing Earth & Environment Education ... Materials Research Center at the University of Chicago, one of nearly 30 NSF-supported Materials ...

165

The European Bioinformatics Institute's data resources

The WHO Expert Committee on Biological Standardization authorized the National Institute for Medical Research to establish an International Reference Preparation of Erythropoietin on the basis of the...Full Text Available

1966-01-01

166

Studies of the action of hypoglycin-a, a hypoglycaemic substance

As the amount of biological data grows, so does the need for biologists to store and access this information in central repositories in a free and unambiguous manner. The European Bioinformatics Institute...Full Text Available

2003-01-01

167

Reporting Problems to FDA

Some biological effects of hypoglycin-A, a compound isolated from the fruit of Blighia sapida, have been investigated. Administration of this compound to animals caused drowsiness...Full Text Available

1958-06-01

168

Medline Plus

Enter Search terms A-Z Index Home Food Drugs Medical Devices Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco ...

169

Real-time neutron scattering investigations of biological signal transduction dynamics

Real-time neutron scattering investigations of biological signal transduction dynamics

During their catalytic cycle, proteins involved in biological signal transduction undergo unexpectedly large conformational changes, which are at the core of their biological functioning. Until now it has been extremely difficult to obtain experimental insight into the nature of these conformational changes. Mathematical modeling and time-resolved X-ray crystallography have resulted in probable routes along which these conformational changes may take place, but so far this fundamental biological phenomenon has hardly been tackled experimentally. Here, we report on an attempt to observe structural changes in Photoactive Yellow Protein with time-resolved small-angle neutron scattering using diffractometer D22 at the high-flux reactor of the Institut Laue-Langevin, Grenoble, France.

2005-07-01

170

Real Time Trajectory Planning for Groups of Unmanned ...

During their catalytic cycle, proteins involved in biological signal transduction undergo unexpectedly large conformational changes, which are at the core of their biological functioning. Until now it has been extremely difficult to obtain experimental insight into the nature of these conformational changes. Mathematical modeling and time-resolved X-ray crystallography have resulted in probable routes along which these conformational changes may take place, but so far this fundamental biological phenomenon has hardly been tackled experimentally. Here, we report on an attempt to observe structural changes in Photoactive Yellow Protein with time-resolved small-angle neutron scattering using diffractometer D22 at the high-flux reactor of the Institut Laue-Langevin, Grenoble, France

2005-04-11

171

... kinematic model for the robots and designed ... theoretic approach for modeling mobile robot teamn formations". ... "UUV teams, control from a biological ...

2005-08-22

172

R virgatipes

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_virgatipes/r_virgatipes.html Page Contact Information: SESC Webmaster Page ... ...

173

R sphenocephala

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_sphenocephala/r_sphenocephala.html Page Contact Information: SESC Webmaster Page ... ...

174

R heckscheri

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_heckscheri/r_heckscheri.html Page Contact Information: SESC Webmaster Page ... ...

175

R grylio

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_grylio/r_grylio.html Page Contact Information: SESC Webmaster Page ... ...

176

R clamitans

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_clamitans/r_clamitans.html Page Contact Information: SESC Webmaster Page ... ...

177

R capito

Probiotic Bacteria as Biological Control Agents in Aquaculture

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_capito/r_capito.html Page Contact Information: SESC Webmaster Page ... ...

178

There is an urgent need in aquaculture to develop microbial control strategies, since disease outbreaks are recognized as important constraints to aquaculture production and trade and since the development...Full Text Available

2000-12-01

179

Orphan GPCR research

New Developments in the Use of Histamine and Histamine Receptors

Orphan G protein-coupled receptors (GPCRs) are receptors lacking endogenous ligands. Found by molecular biological analyses, they became the roots of reverse pharmacology, in which receptors are attempted...Full Text Available

2008-03-01

180

Neomusotima Fuscolinealis (Lepidoptera: Pryalidae) is an Unsuitable Biological Control Agent of Lygodium japonicum

Histamine and the histamine receptors are important regulators of a plethora of biological processes, including immediate hypersensitivity reactions and acid secretion in the stomach. In these...Full Text Available

2011-04-01

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181

Molecular Aspects of Thyroid Hormone Actions

... la polilla fueron importadas a la facilidad de cuarentena en el Laboratorio de Control Biológico de Florida, ... ...

182

Microfluidic local perfusion chambers for the visualization and manipulation of synapses

Cellular actions of thyroid hormone may be initiated within the cell nucleus, at the plasma membrane, in cytoplasm, and at the mitochondrion. Thyroid hormone nuclear receptors (TRs) mediate the biological...Full Text Available

2010-04-01

183

Labelling methods for #alpha#-melanocyte stimulating hormone: an immunological and biological comparative study

SummaryThe polarized nature of neurons as well as the size and density of synapses complicates the manipulation and visualization of cell biological processes that control synaptic...Full Text Available

2010-04-15

184

How frugal is mother nature with haplotypes?

1981. p. 21. France Ghanem, G. Roland, MT Libert, A. Gossuin, A. Maerschalk,

1981-04-01

185

General Disclaimer One or more of the Following Statements may ...

Motivation: Inference of haplotypes from genotype data is crucial and challenging for many vitally important studies. The first, and most critical step, is the ascertainment of a biologically...Full Text Available

2009-01-01

186

Fixation of CO_2 and export of photosynthate by the carpel in Pisum sativum

Hie synthesis of diverse biologically important compounds, under condi- tions which existed on the earth in the initial period of its evolution, ha; ...

187

Evaluating Phylogenetic Congruence in the Post-Genomic Era

... School of Plant Biology. v. 23(2) p. 316-322. carbon dioxide absorption carbon

1970-01-01

188

Estimation of "1"3"7Cs body burden in Japanese, 2

Congruence is a broadly applied notion in evolutionary biology used to justify multigene phylogeny or phylogenomics, as well as in studies of coevolution, lateral gene transfer, and as evidence for...Full Text Available

2011-01-01

189

DNA synthesis inhibition in mammalian cells as a test for mutagenic carcinogens

The biological half-life of "1"3"7Cs in the total body of human subjects was determined in 23 individuals of Japanese male adult in their normal works by measuring amount of "1"3"7Cs in both their total body and daily urine in the same period. For the group, the value was determined by averaging the half-lives for individuals, by comparing the mean body burden and the mean daily urinary excretion, or by applying a curve fitting method to the body burden estimate. The biological half-life averaged 86 days, ranging from 50 to 161 days. The averages of the biological half-lives for the group were 83, 87 and 82 days in the different periods of observation. By the curve fitting method, 85 days was found for the group. The biological half-life for the individuals depended on both body weight and age, to a lesser extent, of the subjects. (author).

190

Computational biology for ageing

Current models of DNA repair of biological damage are reviewed correlating the similarity between carcinogenesis and mutagenesis theories. (PCS)

1979-01-01

191

Combining Satellite and in Situ Data with Models to Support Climate Data Records in Ocean Biology

High-throughput genomic and proteomic technologies have generated a wealth of publicly available data on ageing. Easy access to these data, and their computational analysis, is of great importance in...Full Text Available

2011-01-12

192

The satellite ocean color data record spans multiple decades and, like most long-term satellite

2011-01-01

193

Clinical spectrum

Chemical and Biological Warfare: A Manageable Problem

A tunable diode laser is used to obtain infrared spectra of carbon dioxide in biological materials. The spectral resolution is sufficient to readily distinguish differing isotopic species. The technique may prove useful in clinical tests.

1987-11-01

194

CAAX-box protein, prenylation process and carcinogenesis

... On 20 March 1995, members from the religious cult Aum Shinrikyo released sarin and VX nerve gas into the Tokyo subway system. At the height of ...

2003-01-27

195

Breast cancer in the elderly.

CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological activity, signal transduction via protein...Full Text Available

196

Bioterrorism and Biocrimes: The Illicit Use of Biological Agents ...

Breast cancer in the elderly has attracted considerable interest in recent years for three main reasons. Firstly, information concerning the profile (clinical and biological) of the disease in the geriatric...Full Text Available

1995-11-01

197

Biology of lichen communities in Antarctica. - NASA

... view on the utility of such attacks, see JH Rothschild, Tomorrow's Weapons ... Aum Shinrikyo may have had a stolen vaccine anthrax strain incapable ...

2001-02-01

198

Biology of Pseudomonas stutzeri

-Estudio sobre la fijacion de nitrogeno, fotosintesis y reconolizacion ... - Fotosintesis y relaciones hidricas en liquenes nanofruticulosos antarticos. ...

199

Biological effects of Maytenus ilicifolia extract on the survival of Escherichia coli AB1157 and BH110 strains

Pseudomonas stutzeri is a nonfluorescent denitrifying bacterium widely distributed in the environment, and it has also been isolated as an opportunistic pathogen from humans. Over the...Full Text Available

2006-06-01

200

Biological Studies of Bagous Hydrillae

English 2004 [2 p.] Brazil Soares, SF Dire, Glaucio Abreu, Paulo Jesus,

2004-08-25

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201

Analysis of Fisheries and Aquaculture

... Ceratophyllaceas Ceratophyllum doemesm 96 4 3 4 107 Convulivulacme Ipomea aquatica 13 13 Haloragaceae Myriophyflum trahycatpum 15 15 ...

1994-09-01

202

An Artificial Immune System-Inspired Multiobjective ...

... abundance though an effect on escapement. The lobster aquaculture model continues to be updated as new biological ... become available. A monograph on the economics of aquaculture is near completion....

203

Allozyme Divergence in Two Syntopic Liolaemus of the Liolaemus monticola Group (Squamata: Tropiduridae)

... BFS Breadth-First Search BIS Biological Immune System CCNA Cisco-Certified Network Associate CDIS Computer Defense Immune System ...

2007-03-01

204

A unified framework for biological evolution and stochastic quantization

... shareware for population genetic analysis. Molecular Biology and Biotecnology Centre, Univ. of Alberta, Canada. enlarge figure Fig. ... ...

205

CERN Document Server

We investigate the profound relation between the equations of biological evolution and quantum mechanics by writing a biologically inspired equation for the stochastic dynamics of an ensemble of particles. Interesting behavior is observed which is related to a new type of stochastic quantization. We find that the probability distribution of the ensemble of particles can be decomposed into eigenfunctions associated to a discrete spectrum of eigenvalues. In absence of interactions between the particles, the out-of-equilibrium dynamics asymptotically relaxes towards the fundamental state. This phenomenon can be related with the Fisher theorem in biology. On the contrary, in presence of scattering processes the evolution reaches a steady state in which the distribution of the ensemble of particles is characterized by a Bose-Einstein statistics. In order to show a concrete example of this stochastic quantization we have solved ...

2010-01-01

206

A framework for evolutionary systems biology

The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias

BackgroundMany difficult problems in evolutionary genomics are related to mutations that have weak effects on fitness, as the consequences of mutations with large effects are often...Full Text Available

207

The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: Implication for Krabbe Disease

BackgroundInterim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs). Data Monitoring Committees (DMCs) often...Full Text Available

208

The protein storage vacuole

Krabbe disease (KD) is an inherited neurological disorder caused by the deficiency of galactocerebrosidase activity resulting in accumulation of psychosine, which leads to energy depletion,...Full Text Available

2008-06-01

209

The kiwifruit lycopene beta-cyclase plays a significant role in carotenoid accumulation in fruit

Storage proteins are deposited into protein storage vacuoles (PSVs) during plant seed development and maturation and stably accumulate to high levels; subsequently, during germination the storage...Full Text Available

2001-12-10

210

The effect of deposits on the tubes of a horizontal steam generator on its thermal-hydraulic characteristics

The composition of carotenoids, along with anthocyanins and chlorophyll, accounts for the distinctive range of colour found in the Actinidia (kiwifruit) species. Lutein and beta-carotene...Full Text Available

2009-09-01

211

British Library Electronic Table of Contents (United Kingdom)

Analytical relations are obtained for estimating how the distributions of temperature and heat flux vary along a steam-generating tube and how the steam-generator power output reduces due to formation and accumulation of deposits.

2007-01-01

212

The effect of deposits on the tubes of a horizontal steam generator on its thermal-hydraulic characteristics

The Formation of Anthocyanic Vacuolar Inclusions in Arabidopsis thaliana and Implications for the Sequestration of Anthocyanin Pigments

Analytical relations are obtained for estimating how the distributions of temperature and heat flux vary along a steam-generating tube and how the steam-generator power output reduces due to formation and accumulation of deposits.

2007-12-01

213

Stress and Stress-Induced Neuroendocrine Changes Increase the Susceptibility of Juvenile Oysters (Crassostrea gigas) to Vibrio splendidus

Anthocyanins are flavonoid pigments that accumulate in the large central vacuole of most plants. Inside the vacuole, anthocyanins can be found uniformly distributed or as part of sub-vacuolar pigment...Full Text Available

2010-01-01

214

Stereocomplexed PLA-PEG Nanoparticles with Dual-Emissive Boron Dyes for Tumor Accumulation

Oysters are permanently exposed to various microbes, and their defense system is continuously solicited to prevent accumulation of invading and pathogenic organisms. Therefore, impairment of the animal's...Full Text Available

2001-05-01

215

Specific accumulation of arsenic compounds in green turtles (Chelonia mydas) and hawksbill turtles (Eretmochelys imbricata) from Ishigaki Island, Japan

Responsive biomaterials play important roles in imaging, diagnostics, and therapeutics. Polymeric nanoparticles (NPs) containing hydrophobic and hydrophilic segments are one class of biomaterial...Full Text Available

2010-09-28

216

Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease

Concentrations of total arsenic (As) and individual compounds were determined in green and hawksbill turtles from Ishigaki Island, Japan. In both species, total As concentrations were highest in muscle among the tissues. Arsenobetaine was a major compound in most tissues of both turtles. High concentrations of trimethylarsine oxide were detected in hawksbill turtles. A significant negative correlation between standard carapace length (SCL), an indicator of age, and total As levels in green turtles was found. In contrast, the levels increased with SCL of hawksbill turtles. Shifts in feeding habitats with growth may account for such a growth-dependent accumulation of As. Although concentrations of As in marine sponges, the major food of hawksbill turtles are not high compared to those in algae eaten by green turtles, As concentrations in hawksbill turtles were higher than those in green turtles, indicating that hawksbill turtles may have a specific ...

2008-05-15

217

Regulation and Function of Escherichia coli Sugar Efflux Transporter A (SetA) during Glucose-Phosphate Stress?

Accumulated lines of evidence suggest that hyperimmune responses to periodontal bacteria result in the destruction of periodontal connective tissue and alveolar bone. The etiological roles of periodontal...Full Text Available

218

Reduced Accumulation of ABA during Water Stress in a Molybdenum Cofactor Mutant of Barley ¹

Accumulation of certain nonmetabolizable sugar-phosphates (including α-methyl glucoside-6-phosphate) in Escherichia coli is growth inhibitory and elicits the glucose-phosphate...Full Text Available

2011-01-01

219

Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat

A barley (Hordeum vulgare L.) mutant (Az34) has been identified with low basal levels of abscisic acid (ABA) and with reduced capacity for producing ABA in response to water stress....Full Text Available

1989-06-01

220

Proline Betaine Accumulation and Metabolism in Alfalfa Plants under Sodium Chloride Stress. Exploring Its Compartmentalization in Nodules1

The widely accepted oxidative stress theory of aging postulates that aging results from accumulation of oxidative damage. Surprisingly, data from the longest-living rodent known, naked mole-rats [MRs;...Full Text Available

2009-03-03

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221

Programmed cell death in castor bean endosperm is associated with the accumulation and release of a cysteine endopeptidase from ricinosomes

The osmoprotectant Pro betaine is the main betaine identified in alfalfa (Medicago sativa). We have investigated the long-term responses of nodulated alfalfa plants to salt stress,...Full Text Available

2004-07-01

222

Pharmacokinetics of ceftriaxone during plasma exchange in polyarteritis nodosa patients.

The cells of the endosperm of castor bean seeds (Ricinus communis) undergo programmed cell death during germination, after their oil and protein reserves have been mobilized. Nuclear...Full Text Available

1999-11-23

223

Monitoring of NK-Cell Immunotherapy using non-invasive Imaging Modalities

Plasma exchange (PE) is currently being used to treat a variety of disorders involving immune complexes, such as polyarteritis nodosa. This procedure removes endogenous toxic components that accumulate...Full Text Available

1994-07-01

224

Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration

Cancer immunotherapies can be guided by cellular imaging techniques, which can identify the presence or absence of immune-cell accumulation in the tumor tissue in-vivo and in real time. This...Full Text Available

2010-08-01

225

Microdamage Repair and Remodeling Requires Mechanical Loading

BackgroundMitochondrial dysfunction, oxidative damage and the accumulation of somatic mutations in mitochondrial DNA (mtDNA) have been associated with certain neurodegenerative disorders....Full Text Available

226

Methyl Jasmonate Induces Traumatic Resin Ducts, Terpenoid Resin Biosynthesis, and Terpenoid Accumulation in Developing Xylem of Norway Spruce Stems1

Bone remodeling is necessary to avoid microdamage accumulation, which could lead to whole-bone failure. Previous studies have shown that this bone-repair mechanism is triggered by osteocyte apoptosis....Full Text Available

2010-04-01

227

Mechanism of L-glutamate transport in membrane vesicles from Bacillus stearothermophilus.

Norway spruce (Picea abies L. Karst) produces an oleoresin characterized by a diverse array of terpenoids, monoterpenoids, sesquiterpenoids, and diterpene resin acids that can protect...Full Text Available

2002-07-01

228

Malignant Catarrhal Fever of Cattle Is Associated with Low Abundance of IL-2 Transcript and a Predominantly Latent Profile of Ovine Herpesvirus 2 Gene Expression

In the presence of electrochemical energy, several branched-chain neutral and acidic amino acids were found to accumulate in membrane vesicles of Bacillus stearothermophilus. The membrane vesicles contained...Full Text Available

1989-02-01

229

Lomi cleans up at Monticello

BackgroundMalignant catarrhal fever (MCF) is a lethal disease of cattle, characterized by vasculitis, necrosis, and accumulation of activated, dysregulated cytotoxic lymphocytes...Full Text Available

230

Light and Dark Controls of Nitrate Reduction in Wheat (Triticum aestivum L.) Protoplasts ¹

As evidence of its effectiveness rapidly accumulates, the Lomi process has most recently been used to decontaminate the recirculation loops and the reactor water clean-up unit of a BWR at Monticello in the United States. An average decontamination factor of 23 was achieved in the recirculation loops.

1985-01-01

231

International Space Station Overview - NASA

Protoplasts were isolated from the leaves of nitrate-cultured wheat (Triticum aestivum L. var. Frederick) seedlings. When incubated in the dark, protoplasts accumulated nitrite under...Full Text Available

1982-02-01

232

Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease

(accumulates & stores brine for disposal). Separator. (separates water from purge gases). ? Purge pump periodically vent ... Reactor Health. Sensor. ( verifies reactor is operating w/n limits) ... Waste and Hygiene Compartment ...

233

Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

Stargardt disease (STGD) is the major form of inherited juvenile macular degeneration. Pyridinium bis-retinoid A2E is a major component of lipofuscin which accumulates in retinal pigment epithelium...Full Text Available

2010-10-12

234

Hypobetalipoproteinemia with accumulation of an apoprotein B-like protein in intestinal cells. Immunoenzymatic and biochemical characterization of seven cases of Anderson's disease.

BackgroundMethamphetamine (METH), an addictive psycho-stimulant drug with euphoric effect is known to cause neurotoxicity due to oxidative stress, dopamine accumulation and glial...Full Text Available

235

Heat Stress Enhances the Accumulation of Polyadenylated Mitochondrial Transcripts in Arabidopsis thaliana

We describe here seven cases (from five kindreds) of Anderson's disease, which is characterized by diarrhea, steatorrhea, hypobetalipoproteinemia with low levels of cholesterol, triglycerides, and phospholipids,...Full Text Available

1986-08-01

236

Ghosts of Yellowstone: Multi-Decadal Histories of Wildlife Populations Captured by Bones on a Modern Landscape

BackgroundPolyadenylation of RNA has a decisive influence on RNA stability. Depending on the organisms or subcellular compartment, it either enhances transcript stability or targets...Full Text Available

237

Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent

Natural accumulations of skeletal material (death assemblages) have the potential to provide historical data on species diversity and population structure for regions lacking decades of wildlife monitoring,...Full Text Available

238

First Evidence of Division and Accumulation of Viable but Nonculturable Pseudomonas fluorescens Cells on Surfaces Subjected to Conditions Encountered at Meat Processing Premises?

Harmful algal blooms, caused by rapid growth and accumulation of certain microalgae in the ocean, pose considerable impacts on marine environments, aquatic industries and even public health. Here, we...Full Text Available

2005-01-01

239

Experimental Approaches to the Study of A2E, a Bisretinoid Lipofuscin Chromophore of Retinal Pigment Epithelium

Cleaning and disinfection of open surfaces in food industry premises leave some microorganisms behind; these microorganisms build up a resident flora on the surfaces. Our goal was to explore the phenomena...Full Text Available

2007-05-01

240

Epicuticular Wax Accumulation and Fatty Acid Elongation Activities Are Induced during Leaf Development of Leeks1

Bisretinoid lipofuscin compounds that accumulate in retinal pigment epithelial (RPE) cells are implicated in the pathogenesis of some forms of macular degeneration. In the development of approaches...Full Text Available

2010-01-01

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241

Effects of NaCl on Proline Synthesis and Utilization in Excised Barley Leaves 1

Epicuticular wax production was evaluated along the length of expanding leek (Allium porrum L.) leaves to gain insight into the regulation of wax production. Leaf segments from the...Full Text Available

1998-03-01

242

Effect of chronic fractionated low-dose gamma irradiation on division potential of human embryonic cells in vitro

Proline accumulation in NaCl-treated excised barley (Hordeum vulgare var Larker) leaves was studied. Leaves were treated by placing the cut end in NaCl solutions and allowing the salt...Full Text Available

1983-07-01

243

Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice

We investigated the in vitro phenotypic transformation of human embryo (HE) cells that were repeatedly irradiated (7.5 cGy once a week) throughout their life-span. Irradiation was repeated until the cells had accumulated 195 cGy (equivalent to the 26th passage). Samples of cells were assayed for survival by colony formation, as well as for mutation at the hypoxanthine guanine phosphoribosyl transferase (HGPRT) locus and for transformation by focus formation. The life-span (mean number of population doublings) of multiply irradiated cells with a total dose of 97.5 cGy was slightly but significantly prolonged over that of controls. After HE cells had accumulated 195 cGy, the maximum number of divisions increased to 130-160% of the number in non-irradiated control cells. Transformed foci were not observed until cells had accumulated 97.5 cGy, and then increased with the increasing accumulation of ...

1991-12-01

244

Devising, Implementing, and Evaluating Interventions to Eliminate Health Care Disparities in Minority Children

In chronic kidney disease, fibroblast dysfunction causes renal fibrosis and renal anemia. Renal fibrosis is mediated by the accumulation of myofibroblasts, whereas renal anemia is mediated by the reduced...Full Text Available

2011-10-03

245

Development on the core technologies for tritium removal processes (I).

Despite an accumulating body of literature addressing racial/ethnic disparities in children’s health and health care, there have been few published studies of interventions that have...Full Text Available

2009-11-01

246

Core technologies for Tritium removal processes (I).

At Wolsung NPP, three more CANDU reactors will be operated soon, and the tritium accumulation in the moderator and coolant systems was estimated to be greatly increased. In order to reduce tritium exposure for nuclear safety at Wolsung, a study was carrie...

1993-01-01

247

Cathepsin K Null Mice Show Reduced Adiposity during the Rapid Accumulation of Fat Stores

In case of operating both Wolsung Nuclear Units 1 and 2 without operating tritium removal facilities, it is estimated that tritium in 2013 would be accumulated up to about 30 million Ci that would result in about 2,300 man-rem of tritium exposure to opera...

1992-01-01

248

Can Deterministic Mechanical Size Effects Contribute to Fracture and Microdamage Accumulation in Trabecular Bone?

Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white...Full Text Available

249

Blockage by acetylene of nitrous oxide reduction in Pseudomonas perfectomarinus.

Failure of bone under monotonic and cyclic loading is related to the bone mineral density, the quality of the bone matrix and the evolution of microcracks. The theory of linear elastic fracture...Full Text Available

2010-07-21

250

Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound

Suspensions of denitrifying cells of Pseudomonas perfectomarinus reduced nitrate and nitrate as expected to dinitrogen; but, in the presence of acetylene, nitrous oxide accumulated when nitrate or nitrate...Full Text Available

1976-04-01

251

Application of 18F-fluorodeoxyglucose positron emission tomography to detection of proximal lesions of obstructive colorectal cancer

Fish living in contaminated environments accumulate toxic chemicals in their tissues. Biomarkers are needed to identify the resulting health effects, particularly focusing on early changes at a subcellular...Full Text Available

2006-06-01

252

Accumulation of Plasmodium berghei-Infected Red Blood Cells in the Brain Is Crucial for the Development of Cerebral Malaria in Mice?

In cases of obstructive colorectal cancer (CRC), preoperative diagnosis of the proximal lesion is often difficult when the primary lesion impedes the passage of the endoscope. The aim of this study was to evaluate the usefulness of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) in such cases. A total of 52 obstructive CRC patients who underwent preoperative FDG-PET and subsequent surgical resection were retrospectively reviewed. The correlation between characteristics of the proximal lesion and FDG-PET findings was analyzed statistically. There was a significant correlation between the proximal lesion size and the maximum standardized uptake value (P=0.00016). Abnormal FDG accumulation in the proximal colon indicated the existence of proximal cancer or adenoma with a sensitivity of 50% and a specificity of 100%. There was a significant difference in the distribution of tumor size between the cases with proximal abnormal ...

2010-10-01

253

Accumulation of Long-Chain Glycosphingolipids during Aging Is Prevented by Caloric Restriction

Cerebral malaria is the most severe complication of human infection with Plasmodium falciparum. It was shown that Plasmodium berghei ANKA-induced cerebral malaria was...Full Text Available

2010-09-01

254

ADP-Glucose Pyrophosphorylase, a Regulatory Enzyme for Bacterial Glycogen Synthesis

BackgroundChronic kidney disease and end-stage renal disease are major causes of morbidity and mortality that are seen far more commonly in the aged population. Interestingly, kidney...Full Text Available

255

A Humanin Derivative Reduces Amyloid Beta Accumulation and Ameliorates Memory Deficit in Triple Transgenic Mice

The accumulation of α-1,4-polyglucans is an important strategy to cope with transient starvation conditions in the environment. In bacteria and plants, the synthesis of glycogen and starch occurs...Full Text Available

2003-06-01

256

?Activation of the mitogen-activated protein kinase pathways by heat shock

Humanin (HN), a 24-residue peptide, was identified as a novel neuroprotective factor and shows anti-cell death activity against a wide spectrum of Alzheimer's disease (AD)-related cytotoxicities, including...Full Text Available

257

Uptake and translocation of {sup 137}Cs by Houttuynia cordata (in water culture)

In addition to inducing new transcriptional activities that lead within a few hours to the accumulation of heat shock proteins (Hsps), heat shock activates within minutes the major signaling transduction...Full Text Available

2002-04-01

258

Shredders and riparian vegetation

The water culture experiment of Houttuynia cordata of the medicinal plant was carried out, and basic study on {sup 137}Cs accumulation characteristic and internal circulation in H. cordata in the fruiting stage was investigated since the flowering season. H. cordata accumulated 80% of {sup 137}Cs absorbed unlike K to the root, rhizome, terminal bud of the underground part for the rhizome reproduction. {sup 137}Cs content to the young leaf, spike, involucre increased in the flowering season. Thereafter, {sup 137}Cs was recirculated to the developing organs in second generations such as the rhizome and bud. (author)

2001-08-01

259

Processing of asparagine-linked oligosaccharides in HT-29 cells is a function of their state of enterocytic differentiation: an accumulation of Man/sub 9-8/-GlcNAc_2-Asn species is indicative of an impaired N-glycan trimming in undifferentiated cells

Stream invertebrates that feed on leaf litter are intimately tied to the nature and timing of the litter input. These invertebrates are called shredders; they consume streamside, riparian litter that has become trapped in the stream channel. This plant litter accumulates at the leading edge of obstructions in the current and settles out in pools, alcoves, and other depositional zones. Given the extensive literature that has accumulated over the last 20 years, researchers can now develop a general, testable model that relates riparian plant communities to the stream shredders, which depend upon litter derived from those communities.

1989-01-01

260

Internalized insulin-receptor complexes are unidirectionally translocated to chloroquine-sensitive degradative sites. Dependence on metabolic energy

Studies on the regulation of the enterocytic differentiation of the human colon cancer cell line HT-29, which is differentiated in the absence (Glc"-) but not in the presence of glucose (Glc"+), have recently shown that the post-translational processing of sucrase-isomaltase and particularly its glycosylation vary as a function of cell differentiation. Other studies indicate that in undifferentiated HT-29 Glc"+ cells there is an accumulation of UDP-N-acetylhexosamine, which is involved in the glycosylation process. The purpose of the present work is to investigate whether an overall alteration of protein glycosylation is associated with the inability of HT-29 cells to differentiate. At least three alterations are detected: (i) after a 10-min pulse, the incorporation of D-[2-"3H]mannose in undifferentiated cells is severely reduced, compared to differentiated cells. (ii) After a 24-h period of labeling with D-[2-"3H]mannose, undifferentiated cells ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

261

Accumulation of carbon in northern mire ecosystems

Insulin receptors on the surface of isolated rat adipocytes were photoaffinity labeled at 12 degrees C with the iodinated photoreactive insulin analogue, 125I-B2 (2-nitro-4-azidophenylacetyl)-des-PheB1-insulin, and the pathways in the intracellular processing of the labeled receptors were studied at 37 degrees C. During 37 degrees C incubations, the labeled 440-kDa insulin receptors were continuously internalized (as assessed by trypsin inaccessibility) and degraded such that up to 50% of the initially labeled receptors were lost by 120 min. Metabolic poisons (0.125-0.75 mM 2,4-dinitrophenol (DNP) and 1-10 mM NaF), which led to dose-dependent depletion of adipocyte ATP pools, inhibited receptor loss, and caused up to 3-fold increase in intracellular receptor accumulation. This effect was due to inhibition of intracellular receptor degradation, and there was no apparent effect of the metabolic poisons on initial internalization of the receptors. Following maximal ...

1988-04-25

262

[The indicators of biological age and accelerated aging in liquidators of the consequences of radiation emergency].

The basic feature in the functional ecology of any mire ecosystem is retardation of the effective decay of organic material resulting in a conspicuous accumulation of plant debris as peat overtime. The carbon accumulation process is slow, and climatic change may have an impact on the carbon cycle of peatlands, therefore, it has been of interest to study the rate of carbon accumulation by geological methods from dated peat strata. The approach is hampered by several facts. First, the mires vary enormously as to their vegetation and hydrology and hence their production and decay properties. It follows that a great number of study sites are needed. Second, the peat in mires expands both vertically and laterally, and this requires a spatial reconstruction of carbon accumulation within a mire basin. Third, simple geological methods cannot account for the actual rate of carbon ...

1996-12-31

263

Tumorigenic and tumoricidal actions of ionizing radiations

The biological age (BA) of the majority of the liquidators of the consequences of the radiation accidents in the Navy and of the liquidators of the Chernobyl' APS accident exceeds the medium standard and the DBA (due BA). The index of the BA can be a characteristic of the influence of the social-hygienic factors on the health condition of the Special Risk Subunit--the liquidators of the consequences of the radiation accidents. It was established, that the radiation influence concerns to the factors dramatically increasing the BA and the rate of senescence of the liquidators of the consequences of the radiation accidents. PMID:21809627

2011-01-01

264

Topological modeling of the reactive capacity and biological activity of some amino-polysaccharides

The book is divided into two approximately equal parts. The first four chapters are relatively lengthy and cover the basic principles of radiation biology, carcinogenesis and therapy, along with a brief introduction to radiological physics to orient the reader without background in this specialized related discipline. The remainder consists of twenty-four relatively brief chapters, each covering the radiation biology of a specific organ, tissue, or systems tissues, with emphasis on the tumorigenic and tumoricidal action of ionizing radiations.

1983-01-01

265

British Library Electronic Table of Contents (United Kingdom)

The work is devoted to a microscopic analysis of the reactive capacity of chitin. An algorithm for modeling the deacetylation reaction in a monomeric unit of chitin is described. The reaction coordinate and the potential energy surface topography are determined taking into account the electron-vibrational interaction and low-symmetry perturbations within Jahn-Teller theory. Based on this algorithm, the topological modeling of the deacetylation process is performed for the first time and a mechanism of the biological activity of chitosan is proposed.

2011-01-01

266

The Fenton oxidation mechanism: reactivities of biologically relevant substrates with two oxidizing intermediates differ from those predicted for the hydroxyl radical.

Radionuclide X-ray fluorescence analysis of components of the environment

The application of kinetic probes that allow one to determine relative reactivities of biologically relevant substrates with oxidizing intermediates in the Fenton reagent (H2O2 plus Fe2+ in acidic aqueous...Full Text Available

1994-07-05

267

On new methods for standardization of samples in activation analysis of biological materials

The physical foundations and methodology are described of radionuclide X-ray fluorescence analysis. The sources are listed of air, water and soil pollution, and the transfer of impurities into biological materials is described. A detailed description is presented of the sampling of air, soil and biological materials and their preparation for analysis. Greatest attention is devoted to radionuclide X-ray fluorescence analysis of the components of the environment. (ES).

1983-01-01

268

New humic plant growth stimulant based on the neogene brown coals of Belarus

New standardization techniques of samples in multielement instrumental neutron-activation analysis (INAA) of biological materials (BM) are considered. New methodical developments of sample preparation techniques, BM tableting, creation of comparison standards and standardization of packing material are suggested. Correlated data on concentration of different elements in standard specimens-comparison standards are presented for mass INAA, that is: for phenol-formaldehyde resin-base and human blood-base synthetic standards. 7 refs.; 3 tabs.

1988-06-26

269

British Library Electronic Table of Contents (United Kingdom)

Data on a technology for the manufacture of a new biologically active humic preparation based on the Neogene brown coals deposited in Belarus are presented. The physicochemical properties of the preparation are given, and its biological activity is evaluated; the results of plant cultivation tests in the basic crops of the region?potatoes and grain crops?are also considered.

2011-01-01

270

Ion-Track Membranes and Their Use in Biological and Medical Applications

Generalized genetic code. A note on order-isomorphism/order-equivalence relations

This report is a brief review of biological and medical applications of ion-track membranes. The review aims at informing nuclear physicists about alternative (i.e. non-fundamental-science) use of heavy ion accelerators such as production of micro- and nano-porous materials. The ion-track membranes produced this way are employed in life sciences and numerous technological applications. The author focuses on recent results from the Flerov laboratory in co-operation with other scientific institutions and industrial partners.

2007-05-22

271

Determination of lead in biological and environmental samples by "2"0"3Pb isotope dilution substoichiometric method

Constructive and combinatorial relationships between order-isomorphisms and order-equivalence classes within the generalized genetic code are presented, not only for the biologically relevant groups of order 4, but also for finite groups of arbitrary order. The main result is the derivation of the number (and types) or order-equivalence classes for a group of order n. Finally, an extension of this work to all biologically admissible alternative codes is discussed.

1982-01-01

272

CRC handbook of biological effects of electromagnetic fields

A procedure for the determination of lead in various biological and environmental samples by "2"0"3Pb radioisotope dilution substoichiometric method is presented. The accuracy of the method by comparison with the literature values of reference materials appears to be good. The standard deviation of the method is less than 10%, and detection limit is about 0.1 #mu#g of lead. (author) 5 refs.

273

Biological solubilization of coal in aqueous and nonaqueous media

This book presents the current knowledge about the effects of electromagnetic fields on living matter. The three-part format covers dielectric permittivity and electrical conductivity of biological materials; effects of direct current and low frequency fields; and effects of radio frequency (including microwave) fields. The parts are designed to be consulted independently or in sequence, depending upon the needs of the reader. Useful appendixes on measurement units and safety standards are also included.

1986-01-01

274

Biological effects from electric fields associated with high voltage transmission lines

Current investigations into the biological solubilization of coal with microorganisms focus on the production of solubilizing activity in fungi. Test organisms for this work include a species of the yeast Candida previously isolated from a lignite outcrop, and P. chrysosporium, a filamentous higher fungus which has played a major role in lignin biodegradation research. The studies described are primarily exploratory in nature, and are fundamental to the design of more sophisticated inquiries into the physiology of fungal coal solubilization.

1987-01-01

275

Biological and Chemical Security

Efforts during the past year by the US Department of Energy and the Electric Power Research Institute-funded laboratories to investigate the biological effects from electric fields are described in resume form. Investigations generally have been summarized with objectives, accomplishments of the past year, and some indication of projected studies.

1983-11-01

276

7. Overview of radionuclide X-ray fluorescence analysis of components of the environment

The LLNL Chemical & Biological National Security Program (CBNP) provides science, technology and integrated systems for chemical and biological security. Our approach is to develop and field advanced strategies that dramatically improve the nation's capabilities to prevent, prepare for, detect, and respond to terrorist use of chemical or biological weapons. Recent events show the importance of civilian defense against terrorism. The 1995 nerve gas attack in Tokyo's subway served to catalyze and focus the early LLNL program on civilian counter terrorism. In the same year, LLNL began CBNP using Laboratory-Directed R&D investments and a focus on biodetection. The Nunn-Lugar-Domenici Defense Against Weapons of Mass Destruction Act, passed in 1996, initiated a number of U.S. nonproliferation and counter-terrorism programs including the DOE (now NNSA) Chemical and Biological ...

2002-12-19

277

2004 Reversible Associations in Structure & Molecular Biology

A survey is presented of studies dealing with radionuclide X-ray fluorescence analysis (RXFA) of impurities in the air, water, soil, sediments and biological materials, mainly blood, urine, hair, soft tissues and bones. Tabulated are lists of published works on RXFA of the air, water and biological materials. (ES).

1983-12-01

278

The peak to background method in quantitative ion microprobe analysis of thick biological specimens

The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.

2005-03-23

279

Chromium and manganese levels in biological samples of normal and night blindness children of age groups (3-7) and (8-12) years.

The use of the ratio of the characteristic intensity to the continuum background intensity (P/B ratio) of the X-ray spectrum for a quantitative ion microprobe (IMP) or PIXE (particle induced X-ray emission) analysis of thin biological specimens was proposed previously. The IMP analysis of thick biological specimens is also of considerable practical use. In this paper, the possibility of using the P/B ratio to quantify minor elements in thick biological specimens is investigated. The epoxy resin based standards with gradual concentrations of KCNS up to 0.6 mol/kg and NBS bovine liver were analyzed by a 27 MeV {alpha} particle microprobe. The measured peak to background ratios (between 4.4 to 5.7 keV) agreed well with the theoretical calculations. The calculations showed that the concentration dependence of the P/B ratios was determined mainly by the absorption of X-rays in specimens. The results indicate that the P/B method ...

1991-05-01

280

Biological in situ remediation of a former pond for trickling waste water containing explosives

This study was designed to compare the levels of chromium (Cr) and manganese (Mn) in scalp hair, blood, and urine of night blindness in children age ranged (3-7) and (8-12) years of both genders, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure, was developed as a sample pretreatment, for the determination of Cr and Mn in biological samples of night blindness children. The proposed method was validated by using conventional wet digestion and certified reference samples of hair, blood and urine. The digests of all biological samples were analyzed for Cr and Mn by electrothermal atomic absorption spectrometry. The results indicated significantly higher levels of Cr, whilst low level of Mn in the biological samples (blood and scalp hair) of male and female night blindness children, compared with control subjects of both genders. These data present guidance to clinicians and ...

2010-09-21

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

281

Biological effects of radiowaves and microwaves

WASAG DECON developed a concept for the biological in situ remediation of an TNT-contaminated former seepage pond. This pond is located on the site of an ammunition factory in Lower Saxony. Unit 1982 all the waste water from the production buildings was directed into this pond, including TNT-contaminated water from the flushing of shells. Due to this practice, the sediment of the pond, the underlying soil and the groundwater became contaminated with TNT. The area of the soil contamination adds to abut 2.000 m{sup 2}. The remediation concept includes three steps: 1. Excavation of the most highly contaminated soil with TNT-concentrations above 1000 mg/kg. 2. Reduction of the remaining contamination by a biological in situ treatment using organic and inorganic amendments and mechanical tillage. After about to years of treatment, remediation goals of 50 mg/kg are expected to be reached on most of the area. 3. Contaminations eventually remaining in ...

2003-07-01

282

Effects of ischemic-like insult on myocardial /sup 201/Tl accumulation

Heat production in biological materials due to absorption of radiowaves and microwaves can be used in applications as diverse as cancer treatment and cooking. However, the hazards of overexposure range from hyperthermia to cataracts and internal burns. To maximize the clinical benefits and minimize potential hazards, the biological effects of radiowaves and microwaves must be understood. Dielectric measurements can be used to determine the extent of such effects in various applications and at various levels of exposure. The values of maximum permissible exposure levels that are likely to be recommended aeat production in biological materials due to absorption of radiowaves and microwaves can be used in applications as diverse as cancer treatment and cooking. However, the hazards of overexposure range from hyperthermia to cataracts and internal burns. To maximize the clinical benefits and minimize potential hazards, the ...

1980-01-01

283

Differential expression of fatty acid uptake in 3T3-L1 cells

Despite extensive clinical use of thallium-201 (/sup 201/Tl) for myocardial imaging, the effect of ischemia on myocardial accumulation and release of /sup 201/Tl independent of flow has not been fully defined. Therefore, myocardial accumulation of /sup 201/Tl in response to ischemic-like myocardial injury was assessed in vitro using the cultured fetal mouse heart preparation. Cultured fetal mouse hearts (n . 311) were subjected to injury simulating ischemia by deprivation of oxygen and oxidizable substrates for periods ranging from 15 minutes to 10 hours. The extent of irreversible injury was determined by the percentage of lactic dehydrogenase (LDH) lost from the hearts to the culture medium during recovery from injury. Injury was essentially reversible at 1 hour of insult. The fraction of /sup 201/Tl content in injured compared with control hearts was not significantly lower after 1 hour of insult. By 3 hours of insult, irreversible injury as ...

1983-04-01

284

Accumulation and excretion of metabolized "1"0"6Ru in prawn meat ingested by mice

Cultured 3T3-L1 cells have been used as a model system to investigate the mechanism of fatty acid uptake by adipose tissue. Using a 1:1 molar ratio of /sup 14/C-oleate and defatted bovine serum albumin (BSA), fatty acid (FA) uptake was quantitated at 4/sup 0/ and 37/sup 0/ as cell associated radioactivity. The profile of FA uptake in preadipocytes and adipocytes was biphasic; an initial rapid phase (1-20s) followed by a second slower phase (60-480s). At 37/sup 0/ the initial rate of FA accumulation in preadipocytes was identical to that in adipocytes, whereas the rate of accumulation during the second phase increased 7-fold (100 ..mu..M total FA) as a consequence of adipose conversion. When uptake measurements were made at 4/sup 0/ in adipocytes, the initial rate was identical to that at 37/sup 0/, however the rate of second phase decreased 5-fold. Incubation of /sup 14/C-BSA and nonradiolabeled FA with adipocyte monolayers (100 ..mu..M total ...

1987-05-01

285

eDNA: A Bio-Inspired Reconfigurable Hardware Cell Architecture Supporting Self-organisation and Self-healing

This paper aims at the study of the transfer and accumulation of "1"0"6Ru from marine foods to man through the grazing food chain and evaluation of the radiation exposure to man. As a model, accumulation and excretion of "1"0"6Ru in mice orally administered by the meat of prawn (Penaeus japonicus) which accumulated the radionuclide from the sea water, were examined and compared with those in mice administered by non-radioactive prawn meat mixed with the contaminant in inorganic chemical forms (the control diet); on the latter experiment, the previous evaluation method of the radiation exposure was based. Higher concentrations of "1"0"6Ru in tissues and organs of mice were observed in the former diet than in the latter because of the higher absorption rate of "1"0"6Ru from the gastrointestinal tract (17.4 +- 4.4%, the control diet: 0.7 +- 0.7%) and smaller excretion. As the results of this experiment, the critical organs for ...

286

DEFF Research Database (Denmark)

This paper presents the concept of a biological inspired reconfigurable hardware cell architecture which supports self-organisation and self-healing. Two fundamental processes in biology, namely fertilization-to-birth and cell self-healing have inspired the development of this cell architecture. In biology as well as in our hardware cell architecture it is the DNA which enables these processes. We propose a platform based on the electronic DNA (eDNA) and show through simulation, its capabilities as a new generation of robust reconfigurable hardware platforms. We have created a Java based simulator to simulate our self-organisation and self-healing algorithms and the results obtained from this looks promising.

2009-01-01

287

Use of a trap garden to find additional genetically distinct isolates of the rust fungus Phragmidium violaceum to enhance biological control of European blackberry in Australia

British Library Electronic Table of Contents (United Kingdom)

Biological control agents can be more effective if their populations are genetically diverse, particularly when the target invasive plant comprises a range of genotypes with different susceptibilities and occurs across various microclimates. We report on the use of an efficient approach to find, in the native range, diverse isolates of a rust fungus for biological control. An outdoor trap garden containing various clones of invasive European blackberry (Rubus fruticosus agg.) collected in Australia, each with a different DNA phenotype, was established in France. Within 4?weeks of establishment, the leaf-rust fungus Phragmidium violaceum was recovered from all clones in the garden. Molecular analyses of eight recovered and purified isolates of the fungus from the garden revealed that they w...

2011-01-01

288

Prioritizing areas in the native range of hygrophila for surveys to collect biological control agents

British Library Electronic Table of Contents (United Kingdom)

Native to Southeast Asia, Hygrophila polysperma is an invasive aquatic weed of lotic habitats in the southern United States and Mexico. An increase in the number of water bodies invaded by hygrophila since 1990 suggests that current methods employed to control this weed are inadequate. Classical biological control may be a viable option for long term regulation of hygrophila in the invaded range. In this study, we used the Maximum Entropy Species Distribution Model (MaxEnt) to prioritize climatically suitable native habitats in India and Bangladesh for conducting exploratory surveys to collect biological control agents. In total, 164 point occurrences from the United States and Mexico and 20 predictor variables, including 19 bioclimatic variables and altitude, were used to predict the nati...

2011-01-01

289

Pilot project ''measurement of efficacy'' - biological monitoring of antimony pollution in the Munich test area using a standardized grass culture

Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes

This pilot project was carried out for the purpose of testing methods for active biological monitoring. It covered a period of three years (until September 1994), including two years of exposure. The measurements served to determine pollutant levels in plants used as animal fodder and dust-borne heavy metal concentrations in different sites and, on this basis, to obtain indirect information on human exposure. Among others, the pilot project investigated the suitability of Italian rye-grass as a biological indicator for aluminium, arsenic, cadmium, cobalt, chromium, copper, iron, mercury, magnesium, manganese, nickel, lead, platinum, antimony, titanium, and zinc. (orig./GL).

290

British Library Electronic Table of Contents (United Kingdom)

Abstract Objectives- Cyclodextrins are useful solubilizing excipients that have gained currency in the formulator's armamentarium based on their ability to temporarily camouflage undesirable physicochemical properties. In this context cyclodextrins can increase oral bioavailability, stabilize compounds to chemical and enzymatic degradation and can affect permeability through biological membranes under certain circumstances. This latter property is examined herein as a function of the published literature as well as work completed in our laboratories. Key findings- Cyclodextrins can increase the uptake of drugs through biological barriers if the limiting barrier component is the unstirred water layer (UWL) that exists between the membrane and bulk water. This means that cyclodextrins are mo...

2011-01-01

291

On the selection and validation of biological treatment processes. The GDF experience; Le choix et la validation des procedes de traitement biologique. L`experience de GDF

Molecular biology of the renin-angiotensin system

The biological treatment process was selected by Gaz de France (GDF), the French national gas utility, for the de-pollution of an old gas works where the main pollutants are coal tars containing polycyclic aromatic hydrocarbons. Microorganism-based biological treatment techniques may involve bio-reactors, static ground knolls (where oxygen is brought through drains) and dynamic knolls (where oxygenation is carried out by turning up the soil). Issues on sampling, sorting, process testing, site preparation, process control, etc. are reviewed

1996-12-31

292

MGV: a generic graph viewer for comparative omics data

This paper reviews the molecular biology of the renin-angiotensin system. The renin gene structure is analyzed in detail, including an examination of the putative regulatory regions. The combined action of these regulatory sequences would result in the complex, tissue-specific expression and regulation observed in vivo. The expression of the tissue renin-angiotensin systems, which may have important physiological functions, is also described. In addition, the pathway of renin biosynthesis and secretion is reviewed. This includes speculation on the fate of circulating prorenin and the physiological role of multiple renin forms and secretory pathways. The molecular approaches described in this paper have greatly advanced our knowledge of the biology of the renin-angiotensin system. Future studies using these and other approaches should provide further insight into this complex system.

1988-10-01

293

British Library Electronic Table of Contents (United Kingdom)

Motivation: High-throughput transcriptomics, proteomics and metabolomics methods have revolutionized our knowledge of biological systems. To gain knowledge from comparative omics studies, strong data integration and visualization features are required. Knowledge gained from these studies is often available in the form of graphs, and their visualization is especially useful in a wide range of systems biology topics, including pathway analysis, interaction networks or gene models. Especially, it is necessary to compare biological models with measured data. This allows the identification of new models and new insights into existing ones. Results: We present MGV, a versatile generic graph viewer for multiomics data. MGV is integrated into Mayday (Battke et al., 2010). It extends Maydays visual...

2011-01-01

294

Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

British Library Electronic Table of Contents (United Kingdom)

Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is "Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation". At present, more than 150 patients from 16 hosp...

2007-01-01

295

Biological scarcity: looking beyond regulatory exteriors in Taiwan

British Library Electronic Table of Contents (United Kingdom)

Research and bioethical policies are increasingly seen to facilitate, rather than to impede, scientific progress. Bioethical structures, nonetheless, often fail to account for or to shape the specific social surrounds in which scientific research is conducted. In Taiwan, a perceived shortage in human biological donations threatens to hamper stem cell research progress. This paper considers the stalled national biobank project and the lack of a reliable embryo supply for stem cell research, and suggests that one must look beyond regulatory structures in seeking explanations for such shortages. Specific aspects of Taiwan's democratization and social changes combine with problematic relations between patients and physicians to shape the terrain upon which human biologicals are given or withhe...

2011-01-01

296

Applications of CR-39 for the estimation of biological effects of heavy ion irradiation to DNA and living cells

A Bayesian Bioeconometric Model of Invasive Species Control: The Case of the Hemlock Woolly Adelgid

We present two applications of CR-39 to estimate biological effects of heavy ion irradiation. The accurate measurement of fluence of ions using CR-39 is indispensable to calculate the action cross sections for biological effects. Ions with 6 MeV/n at the Medium Energy Beam Course, HIMAC (NIRS) were extracted to the air, and degraded with the air. DNA and living cells were irradiated by ions with various specific energies at several air columns along with the Bragg curve. DNA strand breaks and cell killing were measured and the results were converted to the action cross sections using the fluence measured with CR-39 at the irradiation positions. Another example of the application of CR-39 is to identify whether the ions with a specific energy pass through the cell or stop within the cell. (author)

2001-10-01

297

British Library Electronic Table of Contents (United Kingdom)

In this article we evaluate a US Forest Service plan to mitigate damages from an invasive insect on public, forested land. We develop a dynamic model of infestation and control to explicitly account for biological interactions, baseline conditions, and uncertainty, thus creating a more complete picture of policy impacts than a static cost benefit analysis could provide. We combine the results of the dynamic model with an empirical study of nonmarket forest benefits to create a bioeconomic model of ecosystem management. Estimating the empirical model in a Bayesian framework allows us to treat the economic coefficients of the dynamic model as random variables. We specify distributions for the biological parameters and examine the effects of both biological and economic uncertainty on the pre...

2011-01-01

298

Study on wavelength shortening and upgrading of the free electron laser (FEL)

Lipiodol-CT findings of hepatocellular carcinoma: Correlation with lipiodol accumulation pattern and serum AFP

This study is a task of ''Comprehensive study'' in ''nuclear energy basic technology research'', which is promoted under cooperation of four research institutes. The Electrotechnical Laboratory conducted, in 1991 in the first period of colaboration, on successful oscillation at visible region (598 nm) as the first case in Japan, construction of small type accumulation ring NIJI-IV for FEL, successful oscillation of visible range from 595 to 488 nm by installing optical krystron with maximum frequency in the world, and successful emittance lowering of accumulation beam by wide improvement of the ring. In the optical resonator, studies on minute loss measuring technique and on recovery from mirror deterioration were promoted. In the second period started from fiscal year of 1994, studies on FEL oscillation technique in short wavelength and upgrading of FEL corresponding to a frontier area were started, to succeed an oscillation experiment at 350 ...

299

Evaluation of stability of {sup 99m}Tc-HSA complex during clinical peritoneal dialysis in vivo (short communication); Ocena stabilnosci kompleksu {sup 99m}Tc-HSA in vivo w warunkach klinicznej dializy otrzewnowej (krotkie doniesienie)

Early diagnosis of hepatocellular carcinoma (hepatoma) along with surgical resection is the most appropriate therapeutic modality. For this purpose, there have been many reports concerning the diagnostic value of Lipiodol-CT scan. The authors selected 45 patients with hepatoma during the period of Feb.1986 to Jan. 1988 who received a conventional CT scan, hepatic angiography and a Lipiodol-CT scan. The results were as follows: 1. There was no statistical significant between serum AFP level and mass size, morphology and amount of necrosis. 2. Tumor necrosis was observed in a single massive and multinodular type when the tumor size exceeded 5 cm. 3. Pattern II on Lipiodol-CT, homogenous accumulation of Lipiodol except for the area of inner necrosis, was most frequently demonstrated, which means that a tumor mass with hypervascularity and increased blood flow will attract Lipiodol better. 4. Lipiodol-CT was superior to conventional CT in detecting small, daughter ...

1989-12-15

300

Effect of increased CO sub 2 and decreased O sub 2 on photosynthesis, and carbon allocation in source leaves

For the assessment of the intra-dialysis stability of the {sup 99m}Tc-HSA complex, a scintigraphic scanning of the organs accumulation of the free 99mTcO{sub 4}{sup -} was carried out during peritoneal dialysis. 740 MBg {sup 99m}Tc-HSA in dialization fluid was administered during kinetic peritoneal examination of the patient. The organs accumulating the free pertechnetion (head and neck), as well as whole body imaging of pt were carried out. The results show that the radioactivity is accumulated mainly in peritoneal cavity. Minimal radioactivity was indicated in the head and neck ({approx}2.3% of the total whole body radioactivity). Our results show that the {sup 99m}Tc-HSA complex is stable during 3.5 h peritoneal dialysis in vivo. (author) 6 refs, 3 figs

1997-12-31

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

301

Effect of drought and abscisic acid application on the osmotic adjustment of four wheat cultivars

The effect of raising the rate of photosynthesis on the allocation of carbon between sucrose and starch was studied by means of steady-state radiolabeling. Sugar beet source leaves on intact plants were exposed to ambient levels of CO{sub 2} and O{sub 2} for 3 hrs. Next CO{sub 2} was raised to 600 {mu}LL{sup {minus}3} for 3 hrs then O{sub 2} was decreased to 2% for 3 hrs. Rates of net carbon exchange (NCE), export, and starch and sucrose synthesis were measured. NCER increased by 30% under the combined treatments and the proportion of photosynthate allocated to starch and to sucrose did not change. When O{sub 2} concentration was lowered, NCER increased but export did not and sucrose accumulated. This observation, and our earlier conclusion that export rate usually equals sucrose synthesis rate, lead us to conclude that low O{sub 2} directly inhibited export. Low O{sub 2} treatment causes sucrose to accumulate in a sugar beet leaf which usually ...

1990-05-01

302

Dynamics of accumulation and disappearance of cobalt-60 in wheat-soil system

The accumulation of osmolytes in leaf tissues and the abscisic acid-induced stomatal closure are well-recognized mechanisms associated with drought tolerance in crop plants. We determine the response in terms of osmotic potential and the contents of leaf proline, glycine betaine and soluble sugar at booting and grain filling stages of four wheat (Triticum aestivum L.) cultivars to drought and exogenously applied abscisic acid (ABA) in a pot study. Leaf sample were collected 3, 6 and 9 days after drought induction and at 48 and 72 h of re-watering (recovery). Marked decreases in osmotic potential associated with the accumulation of proline, glycine betaine and soluble sugars occurred under conditions of drought stress Accession 011320 was most sensitive to drought and showed the largest decrease in osmotic potential and least accumulation of proline, sugar and glycine betaine The inhibitory effects of drought stress were ...

2010-02-01

303

Boron-Dependent Degradation of NIP5;1 mRNA for Acclimation to Excess Boron Conditions in Arabidopsis.

The dynamics of transportation, accumulation, disappearance and distribution of "6"0Co in the wheat-soil system was studied by using isotope-tracer techniques for simulated pollutants, and the mathematical model of the behavior was established. Rescilts showed that (1) "6"0Co was transported rapidly in the system after the application on soil surface layer. The uptake of "6"0Co by wheat was mainly via root, and redistribution in all parts of wheat occurred consequently. The concentration in root was much higher than that in other parts of wheat plant. The specific activity of "6"0Co in wheat plant rapidly increased to a maximum value, then decreased. The specific activity of "6"0Co in each part of wheat plant was found in the order of root > straw > husk > seed. (2) "6"0Co is mainly detained with in 6cm of soil surface, and specific activity of "6"0Co in soil present a simple exponential declining with depth of soil. (3) The dynamic law can be described as ...

2008-10-01

304

Atrial natriuretic peptide receptor heterogeneity and effects on cyclic GMP accumulation

Boron (B) is an essential plant micronutrient that is toxic at higher levels. NIP5;1 is a boric acid channel required for B uptake and growth under B deficiency. Accumulation of the NIP5;1 transcript is upregulated under B deficiency in Arabidopsis thaliana roots. To elucidate the mechanism of regulation, the 5' untranslated region (UTR) of NIP5;1 was tested for its ability to confer B-dependent regulation using ?-glucuronidase and green fluorescent protein as reporters. This analysis showed that the 5' UTR was involved in NIP5;1 transcript accumulation in response to B conditions. We also found that high-B conditions trigger NIP5;1 mRNA degradation and that the sequence from +182 to +200 bp in the 5' UTR is required for this mRNA destabilization. In the nip5;1-1 mutant background, a NIP5;1 complementation construct without the 5' UTR produced high levels of mRNA accumulation, increased B concentrations in tissues, and ...

2011-09-01

305

Use of geodetic measurements for analysis of rock bursts and tremors in coal mining

The effects of atrial natriuretic peptide (ANP), oxytocin (OT) and vasopressin (AVP) on guanylate cyclase activity and cyclic GMP accumulation were examined, since these hormones appear to be intimately associated with blood pressure and intravascular volume homeostasis. ANP was found to increase cyclic GMP accumulation in ten cell culture systems, which were derived from blood vessels, adrenal cortex, kidney, lung, testes and mammary gland. ANP receptors were characterized in intact cultured cells using {sup 125}I-ANP{sub 8-33}. Specific {sup 125}I-ANP binding was saturable and of high affinity. Scratchard analysis of the binding data for all cell types exhibited a straight line, indicating that these cells possessed a single class of binding sites. Despite the presence of linear Scatchard plots, these studies demonstrated that cultured cells possess two functionally and physically distinct ANP-binding sites. Most of the ANP-binding sites in ...

1988-01-01

306

Types of nonanticlinal oil and gas traps and their dispersal within the island section of North Sakhalin

Evaluates geodetic surveys of rock strata in the Szombirki black coal mine with coal seams prone to rock bursts. Rock bursts are associated with accumulation of energy in the 60 m thick sandstone layers situated in the coal seam roofs. Two stages of energy release are analyzed: brittle fracture of the sandstone layer, and energy transfer (dynamic load transfer) to underlying rock strata. Effects of energy accumulation and its release on rock strata displacement were measured in mine workings. The measuring points were situated in the roofs of mine roadways influenced by advancing longwall faces. Two types of vertical displacements are comparatively evaluated: uplift before a rock burst, and subsidence after a rock burst. 5 refs.

1988-01-01

307

Return of Ecosystem Function to Restored Bauxite Mines in Western Australia

Questions are examined of prospecting for nonanticlinical traps within North Sakhalin, their spatial distribution and evaluation of the outlook for oil and gas content. Traps of tapering and facial substitution on wings and periclines of local elevations, accumulative bar and erosion-accumulative channel are isolated. THe hypothesis is made that it is possible to form stratigraphic traps above the discrepancy and below it. It is noted that formation of zones of lithological tapering and facial substitution are associated with areas of the exchange of the sedimentation situation. The primary role of the shore and coastal zones in the formation of the examined types of nonanticlinal traps is established. The Okhino-Ekhabinskiy region in North Sakhalin is isolated as the primary object for prospecting for nonanticlinal traps.

1981-01-01

308

British Library Electronic Table of Contents (United Kingdom)

Abstract A critical aspect of reestablishing a self-sustaining Jarrah (Eucalyptus marginata) forest ecosystem to bauxite-mined areas is to ensure that vital ecosystem functions such as litter decomposition and nutrient cycling are returned. Significant research has been undertaken over the past 20 years relating to litter decomposition and nutrient cycling. Studies have shown that litter accumulates rapidly in restored areas (1-4 ton ha-1 yr-1) and the accumulated litter tends to be richer in nitrogen due to intentionally elevated densities of nitrogen-fixing species. This leads to a lower (carbon:nitrogen) C:N ratio (60:1 compared to 130:1 in unmined forest) that may promote mineralization of organic N to inorganic forms in restored areas. The major nutrient store in the unmined forest is...

2007-01-01

309

Rapid self-assembly of Ni nanodots on Si substrate covered by a less-adhesive and heat-accumulated SiO_2 layers

Mechanism of the accumulation effect in laser damage to polymers: appearance of microdamage due to an ionization absorption wave

Rapid self-aggregation of Ni nanodots on Si substrate covered with a thin SiO_2 buffered layer is investigated. The Ni nanodots can hardly self-aggregate on highly heat-dissipated Si substrate with a thermal conductivity of 148 W/m K. Adding a 200-A-thick SiO_2 buffer with an ultralow thermal conductivity of 1.35 W/m K prevents the formation of NiSi_2 compounds, enhances the heat accumulation, and releases the adhesion at Ni/Si interface, which greatly accelerates the self-assembly of Ni nanodots. Dense Ni nanodots with size and density of 30 nm and 7x10"1"0 cm"-"2, respectively, can be formatted after rapid thermal annealing at 850 deg. C for 22 s.

2006-08-14

310

High-resolution sequence stratigraphic framework and its characteristic. Case study of C-P coal measures in Hebei

An investigation was made of the accumulation of laser damage to transparent polymers irradiated with nanosecond pulses from neodymium and ruby lasers. The damage was investigated by the method of scattering and luminescence in the visible and near ultraviolet parts of the spectrum. It was established that there were two stages in laser damage by repeated irradiation with pulses of intensity below the single-shot damage threshold. An absorbing defect evolved during the first stage in such a way as to create a thermal instability in the surrounding matrix. During the second stage this thermal instability caused spatial growth of laser damage because of propagation of an ionization-inducing absorption wave with a front traveling at the rate governed by the electron component of the thermal conductivity.

1984-04-01

311

Hazardous-waste disposal and the clinical laboratory. Final report, May-December 1989

The framework of time-sequence stratigraphy was established according to the point of view of high-resolution sequence stratigraphy. The development characteristic of the sequence, the distribution pattern of strata, the basin evolution and filling, and the relationship between variations of base level and coal accumulation of epicontinental basin were expounded based on the base-level cycles. The result shows that the C-P coal measures in Hebei is a series of basin deposit of inner epicontinental sea. The formation and evolution and sedimentation of the basin is intimately related to the changes of the basin base-level, which controls the development of the coal-accumulation, forming a clear coal-bearing sequence in the cycle. 9 refs., 3 figs.

2001-07-01

312

Fertilizer amendment for improving the phytoextraction of cadmium by a hyperaccumulator Rorippa globosa (Turcz.) Thell

Negligent hazardous waste management has resulted in real threats to public health. The Federal Government has responded to the situation with laws and regulations aimed at the producers of hazardous waste, including clinical laboratories. The Resources Conservation and Recovery Act (RCRA) imposes controls on hazardous waste management through the Code of Federal Regulations (CFR). The Environmental Protection Agency (EPA) and the Department of Transportation (DOT) regulate these activities through 40 CFR and 49 CFR. Most clinical laboratories can operate satellite accumulation points and accumulate, store, transport, and dispose of waste in accordance with EPA and DOT regulations. Regulations pertaining to infectious waste, sure to affect many clinical laboratories, are being developed now by he EPA. The cradle to grave tracking system mandated by the Federal Government can be supplemented by state and local authorities and poses a significant ...

1990-01-01

313

British Library Electronic Table of Contents (United Kingdom)

Purpose Two main pathways of phytoremediation of heavy metal-contaminated soils are phytostabilization and phytoextraction. Some soil amendments can strengthen phytostabilization or phytoextraction through either reducing heavy metal bioavailability in soil or increasing the heavy metal accumulation capacity of the hyperaccumulator (enhancing heavy metal concentration or shoot biomass of the hyperaccumulator). Urea and chicken manure are often used as fertilizers. This research will explore their effects on a newly found hyperaccumulator, Rorippa globosa (Turcz.) Thell., phytoremediating cadmium (Cd). Materials and methods Pot culture experiment was conducted to study the accumulation characteristics of R. globosa at different Cd contamination concentrations under one fertilizer level (1?g...

2011-01-01

314

British Library Electronic Table of Contents (United Kingdom)

A red basil cell line (T2b) rich in rosmarinic acid (RA) was selected for the stable production of anthocyanins (ACs) in the dark. Cell suspension cultures were subjected to mechanical stress through increased agitation (switch from 90 to 150rpm) to determine the relationship between AC and RA accumulation. Cell extracts were analyzed by HPLC and LC-MS, and the resulting data were processed with multivariate statistical analysis. MS and MS/MS spectra facilitated the putative annotation of several complex cyanidin-based ACs, which were esterified with coumaric acid and, in some cases, also with malonic acid. It was also possible to identify various RA-related molecules, some caffeic and coumaric acid derivatives and some flavanones. Mechanical stress increased the total AC and RA contents, ...

2011-01-01

315

Codon-modifications and an endoplasmic reticulum-targeting sequence additively enhance expression of an Aspergillus phytase gene in transgenic canola

British Library Electronic Table of Contents (United Kingdom)

Transgenic plants offer advantages for biomolecule production because plants can be grown on a large scale and the recombinant macromolecules can be easily harvested and extracted. We introduced an Aspergillus phytase gene into canola (Brassica napus) (line 9412 with low erucic acid and low glucosinolates) by Agrobacterium-mediated transformation. Phytase expression in transgenic plant was enhanced with a synthetic phytase gene according to the Brassica codon usage and an endoplasmic reticulum (ER) retention signal KDEL that confers an ER accumulation of the recombinant phytase. Secretion of the phytase to the extracellular fluid was also established by the use of the tobacco PR-S signal peptide. Phytase accumulation in mature seed accounted for 2.6% of the total soluble proteins. The enzy...

2006-01-01

316

Atomic scale simulations of arsenic ion implantation and annealing in silicon

Whole-genome cancer analysis as an approach to deeper understanding of tumour biology

We present results of multiple-time-scale simulations of 5, 10 and 15 keV low temperature ion implantation of arsenic on silicon (100), followed by high temperature anneals. The simulations start with a molecular dynamics (MD) calculation of the primary state of damage after 10ps. The results are then coupled to a kinetic Monte Carlo (MC) simulation of bulk defect diffusion and clustering. Dose accumulation is achieved considering that at low temperatures the damage produced in the lattice is stable. After the desired dose is accumulated, the system is annealed at 800 degrees C for several seconds. The results provide information on the evolution for the damage microstructure over macroscopic length and time scales and affords direct comparison to experimental results. We discuss the database of inputs to the MC model and how it affects the diffusion process.

2004-12-15

317

Value of procalcitonin, C-reactive protein, and neopterin in exacerbations of chronic obstructive pulmonary disease

Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration...Full Text Available

2010-01-19

318

Using long term biological monitoring data to evaluate the recovery of disturbed systems

Objective:The identification of biological markers in order to assess different aspects of COPD is an area of growing interest. The objective of this study was to investigate whether...Full Text Available

2011-01-01

319

Uracil DNA glycosylase uses DNA hopping and short-range sliding to trap extrahelical uracils

Biological monitoring has been conducted in industrially impacted streams near US Department of Energy facilities in Tennessee and Kentucky for almost ten years. A comprehensive Biological Monitoring and Abatement Program, which was developed to meet National Pollutant Discharge Elimination System permit requirements, includes tasks on (1 ) toxicity testing; (2) bioaccumulation in aquatic and terrestrial biota; (3) bioindicators of fish health; and (4) fish, macroinvertebrate, and periphyton community surveys. These studies have been used successfully to characterize spatial trends and demonstrate temporal recovery resulting from remedial actions and pollution abatement activities, identify contaminant sources, and provide data for conducting ecological risk assessments. The program uses multiple lines of evidence to evaluate stream recovery and illustrates the importance of using an integrated approach when determining stream health. An ...

1995-11-05

320

Undergraduate Course and Curriculum Development Program and Curriculum Development in Mathematics: Calculus and the Bridge to Calculus 1994 Awards

The astonishingly efficient location and excision of damaged DNA bases by DNA repair glycosylases is an especially intriguing problem in biology. One example is the enzyme uracil DNA glycosylase (UNG),...Full Text Available

2008-08-05

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321

Two-site exchange revisited: a new method for extracting exchange parameters in biological systems.

... such as biology, physics, geology, materials science, engineering, computer science, and mathematics ... expected to produce course and curricular materials that will be of national interest and widely ...

322

Tissue Effect on Genetic Control of Transcript Isoform Variation

A new analysis is presented which links real volume fractions, relaxation rates, and intracompartmental exchange rates directly with apparent volume fractions and relaxation rates obtained from biexponential...Full Text Available

1989-02-01

323

The hemoglobins of the trematodes Fasciola hepatica and Paramphistomum epiclitum: A molecular biological, physico-chemical, kinetic, and vaccination study

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

324

The fission yeast gene pmt1+ encodes a DNA methyltransferase homologue.

The trematode Fasciola hepatica (Fa.he.) is a common parasite of human and livestock. The hemoglobin (Hb) of Fa.he., a potential immunogen, was chosen for characterization...Full Text Available

2008-10-01

325

The biological and clinical significance of HCG-containing cells in seminoma.

DNA methylation of cytosine residues is a widespread phenomenon and has been implicated in a number of biological processes in both prokaryotes and eukaryotes. This methylation occurs at the 5-position...Full Text Available

1995-01-25

326

The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

The morphological appearance, incidence and prognostic significance of human chorionic gonadotrophin (HCG)-containing cells in seminomas were examined in a retrospective series of 228 orchidectomy specimens,...Full Text Available

1985-04-01

327

Temperature regulates limb length in homeotherms by directly modulating cartilage growth

BackgroundThe aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The...Full Text Available

328

Technological and biological reclamation of overburden dumps in NCL

Allen's Rule documents a century-old biological observation that strong positive correlations exist among latitude, ambient temperature, and limb length in mammals. Although genetic selection for thermoregulatory...Full Text Available

2008-12-09

329

Task-Specific Codes for Face Recognition: How they Shape the Neural Representation of Features for Detection and Individuation

Methods and materials employed by NCL to reclaim treatment of overburden dumps in opencast projects are described. These involve controlling slope stability and erosion (for example by covering with geosynthetic composites or jute/coir mat) and installing a drainage system before planting trees, shrubs and grass. 1 photo.

2000-05-01

330

TOXICITY OF AROMATIC AEROBIC BIOTRANSFORMATION PRODUCTS OF TOLUENE TO HELA CELLS

BackgroundThe variety of ways in which faces are categorized makes face recognition challenging for both synthetic and biological vision systems. Here we focus on two face processing...Full Text Available

331

Sugarcane pests and their management

Petroleum contamination of groundwater is widely recognized as a serious environmental problem. Toluene (methylbenzene) occurs naturally in crude oil and is commonly found as a contaminant in the subsurface as a result of waste disposal and storage activities. Biological transf...

332

Succession of Indigenous Pseudomonas spp. and Actinomycetes on Barley Roots Affected by the Antagonistic Strain Pseudomonas fluorescens DR54 and the Fungicide Imazalil

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

333

Structure of lipid bilayers

In recent years, the interest in the use of bacteria for biological control of plant-pathogenic fungi has increased. We studied the possible side effects of coating barley seeds with the antagonistic...Full Text Available

2001-03-01

334

Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure

The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (L_α) phase lipid bilayers has been too large to...Full Text Available

2000-11-10

335

Sp1/NF?B/HDAC/miR-29b Regulatory Network in KIT-driven Myeloid Leukemia

Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficial renal effects of some medications, such as chelation therapy depend at least partially on the ability...Full Text Available

2009-09-01

336

Shelterin complex and associated factors at human telomeres

SUMMARYThe biologic and clinical significance of KIT overexpression that associates with KIT gain-of- function mutations occurring in subsets...Full Text Available

2010-04-13

337

Seasonal and Annual Variation in Activity in Wild Male Meadow Voles (Microtus Pennsylvanicus).

The processes regulating telomere function have major impacts on fundamental issues in human cancer biology. First, active telomere maintenance is almost always required for full oncogenic transformation...Full Text Available

2011-03-01

338

SWISS MADE: Standardized WithIn Class Sum of Squares to Evaluate Methodologies and Dataset Elements

Project ZEUS was designed to characterize the effects of long-term gamma irradiation on free-ranging meadow voles, and to determine the lowest level of radiation at which biological effects are discernible in the population. Behavioural tests are consider...

1980-01-01

339

SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments

Contemporary high dimensional biological assays, such as mRNA expression microarrays, regularly involve multiple data processing steps, such as experimental processing, computational processing, sample...Full Text Available

340

Room climate - air quality - thermal comfort; Raumklima - Luftqualitaet - Behaglichkeit

BackgroundHigh throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these data...Full Text Available

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

341

Role of copper resistance in competitive survival of Pseudomonas fluorescens in soil.

The article presents measures for the solution of construction-biological problems and for reducing the pollutant load of buildings. (HW) [Deutsch] Der Artikel berichtet ueber Massnahmen ueber Sanierung von baubiologischen Schwachstellen und Schadstoffbelastungen in Gebaeuden. (HW)

1995-12-31

342

Robust parameter extraction for decision support using multimodal intensive care data

A copper-resistant strain (09906) of Pseudomonas fluorescens that was isolated from a citrus grove soil is being investigated as a biological control agent for Phytophthora root rot. Since citrus grove...Full Text Available

1993-02-01

343

Research and development of a new RF-assisted device for bloodless rapid transection of the liver: Computational modeling and in vivo experiments

Digital information flow within the intensive care unit (ICU) continues to grow, with advances in technology and computational biology. Recent developments in the integration and archiving of these...Full Text Available

2009-01-28

344

Regulatory compliance | Mott MacDonald

BackgroundEfficient and safe transection of biological tissue in liver surgery is strongly dependent on the ability to address both parenchymal division and hemostasis simultaneously....Full Text Available

345

Quantification of physical and biological uncertainty in the simulation of the yield of a tropical crop using present-day and doubled CO₂ climates

...broad range of experience in designing and building research and development laboratories for products such as vaccines, blood and sera, biological products, medical devices, solid dosage forms , highly potent products and cytotoxic material. We also have experience in a range of modular laboratories for TSE research, ...

346

Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection

The impacts of climate change on crop productivity are often assessed using simulations from a numerical climate model as an input to a crop simulation model. The precision of these predictions reflects...Full Text Available

2005-11-29

347

Purpose and regulation of stem cells: a systems-biology view from the Caenorhabditis elegans germ line

BackgroundLiquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is one...Full Text Available

348

Proteome of human colon cancer stem cells: A comparative analysis

Stem cells are expected to play a key role in the development and maintenance of organisms, and hold great therapeutic promises. However, a number of questions must be answered to achieve an...Full Text Available

2009-01-01

349

Project resumes: biological effects from electric fields associated with high-voltage transmission lines

AIM: To isolate and identify the biological characteristics of human colon cancer stem cells (SW1116 cells) and further study their proteome.METHODS: SW1116 cells were isolated and cultured with...Full Text Available

2011-03-14

350

Progress in osteoporosis and fracture prevention: focus on postmenopausal women

Abstracts of research projects are presented in the following areas: measurements and special facilities; cellular and subcellular studies; physiology; behavior; environmental effects; modeling, scaling and dosimetry; and high voltage direct current. (ACR)

1980-01-01

351

Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context

In the past decade, we have witnessed a revolution in osteoporosis diagnosis and therapeutics. This includes enhanced understanding of basic bone biology, recognizing the severe consequences of fractures...Full Text Available

2009-01-01

352

Predicting Protein Post-translational Modifications Using Meta-analysis of Proteome Scale Data Sets*S?

BackgroundDifferent microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little overlap,...Full Text Available

353

Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention

Protein post-translational modifications are an important biological regulatory mechanism, and the rate of their discovery using high throughput techniques is rapidly increasingly. To make use of this...Full Text Available

2009-02-01

354

Pathogenic Role of NKT and NK Cells in Acetaminophen-Induced Liver Injury is Dependent on the Presence of DMSO

Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence...Full Text Available

355

Partial Purification and Characterization of Biological Effects of a Lipid Toxin Produced by Mycobacterium ulcerans

Dimethyl sulfoxide (DMSO) is commonly used in biological studies to dissolve drugs and enzyme inhibitors with low solubility. While DMSO is generally thought of as being relatively inert, it...Full Text Available

2008-09-01

356

Parallel Arrays of Geometric Nanowells for Assembling Curtains of DNA with Controlled Lateral Dispersion

Organisms in the genus Mycobacterium cause a variety of human diseases. One member of the genus, M. ulcerans, causes a necrotizing skin disease called Buruli ulcer....Full Text Available

1998-02-01

357

PASBio: predicate-argument structures for event extraction in molecular biology

The analysis of individual molecules is evolving into an important tool for biological research, and presents conceptually new ways of approaching experimental design strategies. However, more...Full Text Available

2008-10-07

358

Overcoming the challenges of membrane protein crystallography

BackgroundThe exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing within...Full Text Available

359

On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function

Membrane protein structural biology is still a largely unconquered area, given that approximately 25% of all proteins are membrane proteins and yet less than 150 unique structures are available. Membrane...Full Text Available

2008-10-01

360

Natural Variation of Drug Susceptibility in Wild-Type Human Immunodeficiency Virus Type 1

Voxel-based prescriptions of deliberately non-uniform dose distributions based on molecular imaging, so-called dose painting or theragnostic radiation therapy, require specification of a transformation...Full Text Available

2009-03-21

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

Multilevel support vector regression analysis to identify condition-specific regulatory networks

Wild-type viruses from the ViroLogic phenotype-genotype database were evaluated to determine the upper confidence limit of the drug susceptibility distributions, or “biological cutoffs,”...Full Text Available

2004-02-01

362

Molecular dynamics of a ?B DNA element: base flipping via cross-strand intercalative stacking in a microsecond-scale simulation

Motivation: The identification of gene regulatory modules is an important yet challenging problem in computational biology. While many computational methods have been proposed to identify...Full Text Available

2010-06-01

363

Molecular biological enhancement of coal biodesulfurization. Final report, October 1988--December 1991

The sequence-dependent structural variability and conformational dynamics of DNA play pivotal roles in many biological milieus, such as in the site-specific binding of transcription factors to target...Full Text Available

2008-09-01

364

Molar extinction coefficients of some biologically important substances

The overall objective of this project was to use molecular genetics to develop strains of bacteria with enhanced ability to remove sulfur from coal, and to obtain data that will allow the performance and economics of a coal biodesulfurization process to be predicted. (VC)

1991-12-01

365

Modeling RNA polymerase competition: the effect of ?-subunit knockout and heat shock on gene transcription level

Reliable values of x-ray and gamma-ray attenuation coefficients of elements and compounds are required in spectrometry as well as in many other scientific, engineering and medical disciplines involving photon radiation

2002-11-15

366

Metabolic Engineering of Poly(3-Hydroxyalkanoates): From DNA to Plastic

BackgroundModeling of a complex biological process can explain the results of experimental studies and help predict its characteristics. Among such processes is transcription in...Full Text Available

367

Memories of John N. Brady: scientist, mentor and friend

Poly(3-hydroxyalkanoates) (PHAs) are a class of microbially produced polyesters that have potential applications as conventional plastics, specifically thermoplastic elastomers. A wealth of biological...Full Text Available

1999-03-01

368

Massive turnover of functional sequence in human and other mammalian genomes

Friends and colleagues remember John N. Brady, Ph.D., Chief of the Virus Tumor Biology Section of the Laboratory of Cellular Oncology, who died much too young at the age of 57 on April 27, 2009 of colon...Full Text Available

369

Mammalian Sirt1: insights on its biological functions

Despite the availability of dozens of animal genome sequences, two key questions remain unanswered: First, what fraction of any species' genome confers biological function, and second, are apparent...Full Text Available

2010-10-01

370

Long-term effects of inhaled uranyl nitrate in rats

Sirt1 (member of the sirtuin family) is a nicotinamide adenosine dinucleotide (NAD)-dependent deacetylase that removes acetyl groups from various proteins. Sirt1 performs a wide variety of functions...Full Text Available

371

Large-scale Analysis of Thermo-stable, Mammalian Proteins Provides Insights into the Intrinsically Disordered Proteome

Rats were exposed to aerosols of "2"3"3U and "2"3"2U nitrate in a study of the long-term biological effects. Preliminary radiation dose estimates show lung > skeleton > kidney in each dose group.

1977-05-01

372

Intrinsic near-24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans

Intrinsically disordered proteins are predicted to be highly abundant and play broad biological roles in eukaryotic cells. In particular, by virtue of their structural malleability and propensity...Full Text Available

2009-01-01

373

IntelliGO: a new vector-based semantic similarity measure including annotation origin

Endogenous circadian clocks are robust regulators of physiology and behavior. Synchronization or entrainment of biological clocks to environmental time is adaptive and important for physiological homeostasis...Full Text Available

2001-11-20

374

Integrase-directed recovery of functional genes from genomic libraries

BackgroundThe Gene Ontology (GO) is a well known controlled vocabulary describing the biological process, molecular function and cellular...Full Text Available

375

Insecticidal properties of genetically engineered baculoviruses expressing an insect juvenile hormone esterase gene.

Large population sizes, rapid growth and 3.8 billion years of evolution firmly establish microorganisms as a major source of the planet's biological and genetic diversity. However, up to 99% of the...Full Text Available

2009-09-01

376

Inferring Stabilizing Mutations from Protein Phylogenies: Application to Influenza Hemagglutinin

Exploring the possibility of enhancing the properties of baculoviruses as biological control agents of insect pests, we tested the effect of expressing an insect gene (jhe) encoding juvenile hormone...Full Text Available

1992-05-01

377

In Vivo RNAi Screening Identifies Regulators of Actin Dynamics as Key Determinants of Lymphoma Progression

One selection pressure shaping sequence evolution is the requirement that a protein fold with sufficient stability to perform its biological functions. We present...Full Text Available

2009-04-01

378

Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic...Full Text Available

2009-10-01

379

Identification of Phloem Involved in Assimilate Loading in Leaves by the Activity of the Galactinol Synthase Promoter1

ObjectiveTo evaluate the effect of different concomitant disease modifying antirheumatic drugs (DMARDs) on the persistence with antitumour necrosis factor (anti-TNF) therapies in...Full Text Available

380

Identification and In Vivo Characterization of NvFP-7R, a Developmentally Regulated Red Fluorescent Protein of Nematostella vectensis

The definition of “minor” veins in leaves is arbitrary and of uncertain biological significance. Generally, the term refers to the smallest vein classes in the leaf, believed to function...Full Text Available

2000-07-01

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381

INVERTEBRATE FAUNA ASSOCIATED WITH TORPEDOGRASS, PANICUM REPENS (CYPERALES: POACEAE), IN LAKE OKEECHOBEE, FLORIDA, AND ...

BackgroundIn recent years, the sea anemone Nematostella vectensis has emerged as a critical model organism for comparative genomics and developmental biology. Although...Full Text Available

382

Human hair genealogies and stem cell latency

... 154. By way of comparison, the aquatic weed Hygrophila polysperma (Roxb.) T. Anderson, a potential target for biological ... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemon...

383

Highly Conserved Regimes of Neighbor-Base-Dependent Mutation Generated the Background Primary-Structural Heterogeneities along Vertebrate Chromosomes

BackgroundStem cells divide to reproduce themselves and produce differentiated progeny. A fundamental problem in human biology has been the inability to measure how often stem cells...Full Text Available

384

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein*

The content of guanine+cytosine varies markedly along the chromosomes of homeotherms and great effort has been devoted to studying this heterogeneity and its biological implications. Already...Full Text Available

385

Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family

Chemical genetics is an emerging approach to investigate the biology of host-pathogen interactions. We screened several inhibitors of ATP-dependent DNA motors and detected the gyrase B inhibitor coumermycin...Full Text Available

2010-12-10

386

Genetic aspects of birth defects: new understandings of old problems

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

387

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model ?

Over the past two decades, combined advances in genetics, developmental biology and biochemistry have transformed the study of human birth defects. This review describes the importance of genome architecture,...Full Text Available

2007-07-01

388

Fusion expression of pedA gene to obtain biologically active pediocin PA-1 in Escherichia coli *

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in...Full Text Available

2010-01-01

389

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

Two heterologous expression systems using thioredoxin (trxA) as a gene fusion part in Escherichia coli were developed to produce recombinant pediocin PA-1. Pediocin...Full Text Available

2011-01-01

390

Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype

Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which...Full Text Available

2008-03-01

391

Experimental Differential Light-Scattering Correction to the Circular Dichroism of Bacteriophage T2

Deficits in prepulse inhibition (PPI) are a biological marker for schizophrenia. To unravel the mechanisms that control PPI, we performed quantitative trait loci (QTL) analysis on 1,010 F2 mice derived...Full Text Available

2007-11-01

392

Evolutionary history and the effect of biodiversity on plant productivity

Experimental techniques are presented that can be used to assay and correct for differential light scattering effects in circular dichroism spectra of biological macrostructures. The assay is based...Full Text Available

1973-01-01

393

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

Loss of biological diversity because of extinction is one of the most pronounced changes to the global environment. For several decades, researchers have tried to understand how changes in biodiversity...Full Text Available

2008-11-04

394

Estimating trace deposition time with circadian biomarkers: a prospective and versatile tool for crime scene reconstruction

DNA double-strand breaks (DSBs) are generally accepted to be the most biologically significant lesion by which ionizing radiation causes cancer and hereditary disease. However, no information on the...Full Text Available

2003-04-29

395

Estimating Impact Forces of Tail Club Strikes by Ankylosaurid Dinosaurs

Linking biological samples found at a crime scene with the actual crime event represents the most important aspect of forensic investigation, together with the identification of the sample donor. While...Full Text Available

2010-09-01

396

Environmental assessment of the Alaskan continental shelf. Final reports of principal investigators, Volume 15. Biological studies

BackgroundIt has been assumed that the unusual tail club of ankylosaurid dinosaurs was used actively as a weapon, but the biological feasibility of this behaviour has not been examined...Full Text Available

397

Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules

The contents of the report include: Identification, documentation and delineation of coastal migratory bird habitat; and an annotated bibliography of literature on Alaska Water Birds.

1981-12-01

398

Endocrine and Neurochemical Effects of 3,4-Methylenedioxymethamphetamine and Its Stereoisomers in Rhesus Monkeys

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available

2011-07-01

399

Emerging diseases in Chiroptera: why bats?

3,4-Methylenedioxymethamphetamine (MDMA) is an amphetamine derivative that elicits complex biological effects in humans. One plausible mechanism for this phenomenon is that racemic MDMA is composed...Full Text Available

2010-08-01

400

Emergence of Switch-Like Behavior in a Large Family of Simple Biochemical Networks

A conference entitled ‘2nd International Berlin Bat Meeting: Bat Biology and Infectious Diseases’ was held between the 19 and 21 of February 2010 in Berlin, Germany. Researchers from...Full Text Available

2010-08-23

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401

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase*

Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing...Full Text Available

2011-05-01

402

Dynamics of ligand substitution in labile cobalt complexes resolved by ultrafast T-jump

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages....Full Text Available

2010-06-25

403

Discovering Networks of Perturbed Biological Processes in Hepatocyte Cultures

Ligand exchange of hydrated metal complexes is common in chemical and biological systems. Using the ultrafast T-jump, we examined this process, specifically the transformation of aqua cobalt (II) complexes...Full Text Available

2008-09-02

404

Differential Regulation of PDE5 Expression in Left and Right Ventricles of Feline Hypertrophy Models

The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs...Full Text Available

405

DECOMP: A PDB decomposition tool on the web

BackgroundThough long known to affect smooth muscle biology, recent studies indicate that phosphodiesterase 5 (PDE5) is also expressed in myocardium. Recognizing that the regulation...Full Text Available

406

Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator

The protein databank (PDB) contains high quality structural data for computational structural biology investigations. We have earlier described a fast tool (the decomp_pdb tool) for identifying and...Full Text Available

407

Cumulative effects of protracted irradiation of Chernobyl exclusive zone plants

Curcumin is a natural product currently in human clinical trials for a variety of neoplastic, preneoplastic, and inflammatory conditions. We previously observed that, in cultured cells, curcumin exhibits...Full Text Available

2009-01-08

408

Cumulative Inflammatory Load Is Associated with Short Leukocyte Telomere Length in the Health, Aging and Body Composition Study

The biological and radiobiological peculiarities of seeds and seedlings of the Rumex confertus and Lupinus polycolor plants, which grown during several generations in plots with different level of radionuclide pollution of the Chernobyl exclusive zone have been investigated.

2005-01-01

409

Crystallization and preliminary X-ray analysis of human liver ?-enolase

BackgroundLeukocyte telomere length (LTL) is an emerging marker of biological age. Chronic inflammatory activity is commonly proposed as a promoter of ...Full Text Available

410

Cryptic invasion by a non-native genotype of the common reed, Phragmites australis, into North America

Enolase is a multifunctional enzyme that plays important roles in many biological and disease processes. α-Enolase from human liver (hENO1) was expressed as a soluble protein and purified by...Full Text Available

411

Computational Challenges in miRNA Target Predictions: To Be or Not to Be a True Target?

Cryptic invasions are a largely unrecognized type of biological invasion that lead to underestimation of the total numbers and impacts of invaders because of the difficulty in detecting them. The distribution...Full Text Available

2002-02-19

412

Comparative analysis of RBE values of two sublines of the Dunning prostate tumor R3327 using different biological characteristics; Vergleichende Bestimmung der RBE - Werte fuer zwei Sublinien des Dunning Prostatatumors R3327 mit unterschiedlichen biologischen Charakterisitika

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach...Full Text Available

2009-01-01

413

Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families

Short communication

1995-12-31

414

Climate change induces demographic resistance to disease in novel coral assemblages

BackgroundMost rapidly evolving gene families are involved in immune responses and reproduction, two biological functions which have been assigned to the carcinoembryonic antigen...Full Text Available

415

Chromosome aberrations in human lymphocytes from the plateau region of the Bragg curve for a carbon-ion beam

Climate change is reshaping biological communities and has already generated novel ecosystems. The functioning of novel ecosystems could depart markedly from that of existing systems and therefore obscure...Full Text Available

2011-02-01

416

Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by dexamethasone.

Radiotherapy with high-energy carbon ion beams can be more advantageous compared to photons because of better physical dose distribution and higher biological efficiency in tumour cell sterilization. Despite enhanced normal tissue sparing, damage incurred by normal cells at the beam entrance is unavoidable and may affect the progeny of surviving cells in the form of inheritable cytogenetic alterations. Furthermore, the quality of the beam along the Bragg curve is modified by nuclear fragmentation of projectile and target nuclei in the body. We present an experimental approach based on the use of a polymethylmethacrylate (PMMA) phantom that allows the simultaneous exposure to a particle beam of several biological samples positioned at various depths along the beam path. The device was used to measure the biological effectiveness of a 60 MeV/amu carbon-ion beam at inducing chromosomal aberrations in G{sub 0}-human peripheral ...

2007-06-15

417

Calculations of physical and chemical reactions produced in irradiated water containing DNA

We introduce cyclophosphamide-induced alopecia (CYP-IA) in C57BL-6 mice as a clinically relevant model for studying the biology of chemotherapy-induced alopecia and for developing anti-alopecia drugs....Full Text Available

1994-04-01

418

Boule and the Evolutionary Origin of Metazoan Gametogenesis: A Grandpa's Tale

Initial results obtained with a Monte Carlo computer program designed to link initial physical events in irradiated liquid water with subsequent chemical and biological events are presented. 10 refs., 4 figs., 3 tabs.

1985-01-01

419

Biology and Medicine Division annual report, 1978-1979

The evolution of sex remains a hotly debated topic in evolutionary biology. In particular, studying the origins of the molecular mechanisms underlying sexual reproduction and gametogenesis (its fundamental...Full Text Available

420

Biology and Effects of Spontaneous Heating in Hay

Summaries of research projects conducted during 1978 and 1979 are presented. Subject areas include research medicine, cancer research, environmental physiology, radiation biophysics, and structural biophysics. (ACR)

1979-01-01

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421

Biological, Life Course, and Cross-Cultural Studies All point Toward the Value of Dimensional and Developmental Ratings in the Classification of Psychosis

The negative consequences of baling hay before it is adequately dried are widely known to producers. Frequently, these problems are created by uncooperative weather conditions that prevent forages from drying (rapidly) to moisture levels that allow safe and stable storage of harvested forages. When ...

422

Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

The diagnostic criteria for schizophrenia in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV1)...Full Text Available

2007-07-01

423

Biological variations in Anopheles darlingi and Anopheles gambiae

Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is 'Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation'. At present, more than 150 patients from 16 hospitals have been successfully treated with these tissues. This paper presents a brief description of the tissue processing, as well as the present Mexican ...

2007-11-01

424

Biological processing and interactions with coal: Summary of activities for the period January 1, 1988--March 31, 1988

A remarkable range of variation has been demonstrated in the biting habits of A. darlingi in South America. At the centre of its area of distribution, the species comprises both anthropo-endophilic...Full Text Available

1956-01-01

425

Biological effects of low level exposures to chemicals and radiation

Biodegradation/solubilization of coal is described. The degradation of dibenzothiophene by two bacterial strains is reported. The effects of adding salicylate to the treatments was also investigated. 2 figs., 5 tabs. (CBS)

1988-01-01

426

Biological conversion of synthesis gas: Quarterly report [No. 3-4, July 1, 1993--September 3, 1993

In May 1990 a group of scientists representing several federal agencies, the International Society of Regulatory Toxicology and Pharmacology, the private sector, and academia met to develop a strategy to encourage the study of the biological effects of low level exposures (BELLE) to chemical agents and radioactivity. A workshop was held in 1991 with seven invited speakers focusing on the toxicological implications of biological adaptations. The selection of topics and speakers was designed to consider critically the concept of hormesis, not only in a broad, conceptual manner, but also at the molecular and biochemical levels. These presentations offered a complementary perspective on the diverse range of molecular mechanisms that can become activated at low levels of toxicant exposure. In addition to chemical toxicology research, an overview of current research on 'Effects of low-dose radiation on the immune response' was presented as well as ...

427

Biological Response to Nonuniform Distributions of ²¹⁰Po in Multicellular Clusters

This report details the status of the Biological Conversion of Synthesis Gas Project. The following tasks are described as being completed: (1) the test plan, (2) culture development, and (3) the mass transfer/kinetic studies. The bioreactor studies (Task 4) are underway. The continuous stirred tank reactor system for the conversion of H{sub 2}S to elemental sulfur using Chlorobium thiosulfatophilum has been studied for varying light intensities. The system was also modified to include both sulfur recovery and cell recycle using ceramic membranes. Studies were also performed to observe the effects of cell recycle using a polysulfone hollow filter membrane module. Work on Task 5, limiting conditions/scale-up, includes a scale-up study with three different size reactors to establish the optimum operating conditions for hydrogen production from synthesis gas by the biological water-gas shift reaction using the photosynthetic bacterium ...

1993-10-01

428

Biological Response Modifier Activity of an Exopolysaccharide from Paenibacillus jamilae CP-7

Radionuclides are distributed nonuniformly in tissue. The present work examined the impact of nonuniformities at the multicellular level on the lethal effects of ²¹⁰Po. A three-dimensional...Full Text Available

2007-09-01

429

Biodiversity and body size are linked across metazoans

An extracellular polysaccharide was purified from culture supernatants of Paenibacillus jamilae CP-7, a gram-positive bacillus that was isolated from compost prepared with olive mill...Full Text Available

2001-07-01

430

Bioaccumulation and toxicity of selenium compounds in the green alga Scenedesmus quadricauda

Body size variation across the Metazoa is immense, encompassing 17 orders of magnitude in biovolume. Factors driving this extreme diversification in size and the consequences of size variation for biological...Full Text Available

2009-06-22

431

Binary Bacterial Toxins: Biochemistry, Biology, and Applications of Common Clostridium and Bacillus Proteins

BackgroundSelenium is a trace element performing important biological functions in many organisms including humans. It usually affects organisms in a strictly dosage-dependent manner...Full Text Available

432

Association of Paraoxonase 1 (PON1) polymorphisms with osteoporotic fracture risk in postmenopausal Korean women

Certain pathogenic species of Bacillus and Clostridium have developed unique methods for intoxicating cells that employ the classic enzymatic “A-B” paradigm for protein toxins. The binary...Full Text Available

2004-09-01

433

Antioxidant Defenses Predict Long-Term Survival in a Passerine Bird

There is increasing evidence of a biochemical link between lipid oxidation and bone metabolism. Paraoxonase 1 (PON1) prevents the oxidation of low-density lipoprotein (LDL) and metabolizes biologically...Full Text Available

2011-02-28

434

Amyloid Oligomer Neurotoxicity, Calcium Dysregulation, and Lipid Rafts

BackgroundNormal and pathological processes entail the production of oxidative substances that can damage biological molecules and harm physiological functions. Organisms have evolved...Full Text Available

435

Ammonium and Nitrate Uptake by the Floating Plant Landoltia punctata

Amyloid proteins constitute a chemically heterogeneous group of proteins, which share some biophysical and biological characteristics, the principal of which are the high propensity to acquire an incorrect...Full Text Available

436

Alteration of the chemical environment disrupts communication in a freshwater fish

Background and AimsPlants from the family Lemnaceae are widely used in ecological engineering projects to purify wastewater and eutrophic water bodies. However, the biology of nutrient...Full Text Available

2007-02-01

437

Actin Fusion Proteins Alter the Dynamics of Mechanically Induced Cytoskeleton Rearrangement

It is well established that changes to the chemical environment can impair development, physiology and reproductive biology; by contrast, impacts on communication have not been widely reported. This...Full Text Available

2006-05-22

438

Accelerated interleaflet transport of phosphatidylcholine molecules in membranes under deformation.

Mechanical forces can regulate various functions in living cells. The cytoskeleton is a crucial element for the transduction of forces in cell-internal signals and subsequent biological responses. Accordingly,...Full Text Available

439

AEROSPACE MEDICINE AND BIOLOGY - NASA Technical Reports Server

Biological membranes are lamellar structures composed of two leaflets capable of supporting different mechanical stresses. Stress differences between leaflets were generated during micromechanical experiments...Full Text Available

1996-09-01

440

A simple method to systematically study oxidatively-modified proteins in biological samples and its applications

Learning curve models have gained widespread acceptance as a technique for analyzing and ...... flight segment in F4 pilots p 163 A91-30966. WILSON, JOHN W . ...

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441

A multistep bioinformatic approach detects putative regulatory elements in gene promoters

Increased oxidative stress with elevated levels of reactive oxygen and nitrogen species (ROS/RNS) plays an important role in the pathophysiology of many disease states. Increased ROS/RNS can...Full Text Available

2010-01-01

442

A Vasculature-Targeting Regimen of Pre-Operative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer

BackgroundSearching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge for...Full Text Available

443

A Position Paper on the Electronic Publication of Nematode Taxonomic Manuscripts

PurposeTaxanes have effects on angiogenesis causing difficulties in separating biologic effects of chemotherapy from those due to angiogenesis inhibitors. This randomized...Full Text Available

2009-05-15

444

A Hot New Twist to Hair Biology

Several nematode species have now attained ‘model organism’ status, yet there remain many niches in basic biological inquiry for which nematodes would be ideal model systems of study....Full Text Available

2006-09-01

445

A Curated Database of miRNA Mediated Feed-Forward Loops Involving MYC as Master Regulator

The vanilloid receptor-1 (VR1, or transient receptor potential vanilloid-1 receptor, TRPV1) is activated by capsaicin, the key ingredient of hot peppers. TRPV1 was originally described on sensory neurons...Full Text Available

2005-04-01

446

A Comprehensive Analysis of the Dynamic Biological Networks in HCV Induced Hepatocarcinogenesis

BackgroundThe MYC transcription factors are known to be involved in the biology of many human cancer types. But little is known about the Myc/microRNAs cooperation in the regulation...Full Text Available

447

Search for a Methanopyrus-proximal last universal common ancestor based on comparative-genomic analysis

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver, which is closely related to hepatitis C and cirrhosis. The molecular mechanisms underlying the hepatocarcinogenesis induced by HCV...Full Text Available

448

British Library Electronic Table of Contents (United Kingdom)

The origin of life is a long-standing mystery puzzling many people. This mystery possesses not only philosophical but also important biological significance. To unveil this mystery, the searches for the root of life, or the last universal common ancestor (LUCA), based on comparative-genomic analysis have been intensively performed on rRNAs, tRNAs and proteins sequences. The current search pointed to a Methanopyrus-proximal LUCA, which opens up the reconstruction of Lucan biology and helps to delineate the evolutionary pathways.

2011-01-01

449

Radiobiology

Possible processes of abiogenic synthesis of biologically important compounds on surface of small bodies in the Solar System

This text-book (electronic book - multi-media CD-ROM) constitutes a course-book - author's collection of lectures. It consists of 13 lectures in which the reader acquaints with the basis of radiobiology: Introduction to radiobiology; Physical fundamentals of radiobiology; Radiation of cells; Modification of radiation damage of cells; Reparation of radiation damage of cells; Radiation syndromes and their modification; Radiation injury; Radiation damage of tissues; Effect of radiation on embryo and fetus; Biological effects of incorporated radionuclides; Therapy of acute irradiation sickness; Delayed consequences of irradiation; Radiation oncology and radiotherapy. This course-book may be interesting for students, post-graduate students of chemistry, biology, physics, medicine as well as for teachers, scientific workers and physicians. (author)

450

Omic Approaches in Environmental Issues

A mixture of aminoacids was irradiated by a scattered proton beam, its energy varying from 4 to 6.6 MeV, by doses up to 5 x 10"1"1 proton/cm"2 for studying the potentiality of abiogenic synthesis of biologically important compounds in space. It was ascertained that increase in the radiation dose and reduction of proton energy involve increase in effectiveness both of destruction of the initial aminoacid (tryptophan, tyrosine, glycine) and synthesis of the relevant dipeptide. Essential influence of mineral substrate on abiogenic synthesis of natural nucleotides under the action of diverse energy sources was pointed out

2004-04-01

451

British Library Electronic Table of Contents (United Kingdom)

Biomonitoring requires the application of batteries of different biomarkers, as environmental contaminants induce multiple responses in organisms that are not necessarily correlated. Omic technologies were proposed as an alternative to conventional biomarkers since these techniques quantitatively monitor many biological molecules in a high-throughput manner and thus provide a general appraisal of biological responses altered by exposure to contaminants. As the studies using omic technologies increase, it is becoming clear that any single omic approach may not be sufficient to characterize the complexity of ecosystems. This work aims to provide a preliminary working scheme for the use of combined transcriptomic and proteomic methodologies in environmental biomonitoring. There are difficulti...

2011-01-01

452

Modelling heat and mass transfer in drying of biological materials. A simplified approach to materials with small dimensions

Influence of anaerobic microbial activity on biosorption of 2,4-dichlorophenol

A simplified approach has been proposed to model the drying of capillary-porous materials with small geometric parameters for practical purposes. Luikov`s theory of mass and heat transfer for capillary-porous bodies was applied to drying of biological materials and it was shown that the thermo diffusion effect can be neglected if the thermal gradient remains small during the whole period of drying. The resulting simplified equations can then be solved using available mathematical software. The simplified equations were applied to drying of wood and a peanut pod

1996-04-17

453

Free radicals and their transformations in irradiated proteins

Biosorption is an important removal mechanism in treating hydrophobic toxic organics in biological reactors. Equilibrium sorption isotherms and sorption kinetics of 2,4-dichlorophenol on live and chemically inactive anaerobic granules were studied. A metabolic inhibitor was used to inactivate the biological activity of the biomass. Results showed that the difference in the biosorption of live and chemically inactive anaerobic granules is not significant. This would suggest that anaerobic biosorption is mainly a physical-chemical process and that metabolic-mediated diffusion in the process is negligible. 12 refs., 3 tabs., 7 figs.

1995-12-31

454

Environmental tobacco smoke and sudden infant death syndrome: a review

Experimental investigation data are systematized of free radical states and processes in irradiated proteins. The investigation is performed by the radiospectral methods. Results are discussed in detail of the study of free radicals electronic structure of amino acids, peptides and proteins formed by the action of ionizing radiation. The specificity is stressed of the study of monocrystalls of these compounds by the method of electronic paramagnetic resonance. The nature is also studied of primary centres formed under the effect of radiation on biologically important compounds and their subsequent reactions in solid and liquid solutions. Ion-radical states of different functional groups of the protein molecule are studied. Prospects of the study and the role of anion-radicals in biological processes are discusses.

455

British Library Electronic Table of Contents (United Kingdom)

Environmental tobacco smoke (ETS), containing the developmental neurotoxicant, nicotine, is a prevalent component of indoor air pollution. Despite a strong association with active maternal smoking and sudden infant death syndrome (SIDS), information on the risk of SIDS due to prenatal and postnatal ETS exposure is relatively inconsistent. This literature review begins with a discussion and critique of existing epidemiologic data pertaining to ETS and SIDS. It then explores the biologic plausibility of this association, with comparison of the known association between active maternal smoking and SIDS, by examining metabolic and placental transfer issues associated with nicotine, and the biologic responses and mechanisms that may follow exposure to nicotine. Evidence indicates that prenatal ...

2006-01-01

456

Conceptual design of a nuclear reactor facility for medical and biological purposes

Conceptual design of a nuclear reactor facility for medical and biological purposes

Optimal neutron energy for boron neutron capture therapy (BNCT) has been studied. Epithermal neutron is superior to thermal neutrons in treating deep-seated tumors. Design of the epithermal neutron column for BNCT has been performed by using a two-dimensional transport calculation code. Aluminum and heavy water are used as moderation materials. A thermal neutron column is also designed using heavy water as thermalization material. The configuration of the facility for treatment and research of BNCT and also for basic radio-biological studies of neutrons has been presented.

1981-09-01

457

In vitro H2AX phosphorylation and micronuclei induction in human fibroblasts across the Bragg curve of a 577MeV/nucleon Fe incident beam

Optimal neutron energy for boron neutron capture therapy (BNCT) has been studied. Epithermal neutron is superior to thermal neutrons in treating deep-seated tumors. Design of the epithermal neutron column for BNCT has been performed by using a two-dimensional transport calculation code. Aluminum and heavy water are used as moderation materials. A thermal neutron column is also designed using heavy water as thermalization material. The configuration of the facility for treatment and research of BNCT and also for basic radio-biological studies of neutrons has been presented. (author).

458

BMBF. The biotechnology 2000 project. Annual report 1994; BMBF. Programm Biotechnologie 2000. Jahresbericht 1994

The space environment consists of a varying field of radiation particles including high-energy ions, with spacecraft shielding material providing the only major protection to astronauts from harmful exposure. Unlike low-linear energy transfer (LET) {gamma} or X-rays, the presence of shielding does not always reduce the radiation risks for energetic charged particle exposure, since the dose delivered by the charged particle increases sharply as the particle approaches the end of its range, a position known as the Bragg peak. The Bragg curve does not necessarily represent the biological damage along the particle traversal, and the 'biological Bragg curve' is dependent on the energy and the type of the primary particle, and may vary for different biological endpoints. Here we used a unique irradiation geometry to measure the biological response across the Bragg curve in human fibroblasts ...

2006-10-15

459

X-ray findings in patients with miliary appearance of metallic mercury after suicide attempt

The `biotechnology 2000` project is supervised by the project sponsor `biology, energy, ecology` at Forschungszentrum Juelich on behalf of the Federal Ministry for Research and Technology. The project activities cover the development of techniques and methods, cell biology, gene structure and gene regulation, photosynthetic production processes, biological hydrogen production, synthetic biology, protein design, neurobiological research, biosystems, plant breeding, phytomedicine and plant protection, the biology of waste disposal methods, research into methods which replace animal experiments, biological safety research, technology risk assessment, and ethical aspects. A general survey introduces the promoted projects, and standardized data sheets briefly introduce the individual activities. The appendix gives the project indices, the indices of joint projects, a ...

1995-11-01

460

Tracing Cadmium from Culture to Spikelet: Noninvasive Imaging and Quantitative Characterization of Absorption, Transport, and Accumulation of Cadmium in an Intact Rice Plant¹^[W]^[OA]

This case report evaluates X-ray findings in patients with miliary accumulation of mercury observed after parenteral application of metallic mercury in a suizide attempt. There are certain discrepancies between clinical symptoms and the X-ray findings. A clear demonstration of mercury in coronary blood vessels is possible by fluoroscopy.

1985-03-01

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461

The metabolism of L-tryptophan by isolated rat liver cells. Effect of albumin binding and amino acid competition on oxidatin of tryptophan by tryptophan 2,3-dioxygenase.

We characterized the absorption and short-term translocation of cadmium (Cd) in rice (Oryza sativa ‘Nipponbare’) quantitatively using serial images observed with a positron-emitting...Full Text Available

2010-04-01

462

The comparative uptake and interaction of several radionuclides in the trophic levels surrounding the Los Alamos Meson Physics Facility (LAMPF) waste water ponds

1. Novel methods, using L-[ring-2-14C]tryptophan, are described for the measurement of tryptophan 2,3-dioxygenase activity and tryptophan accumulation in isolated rat liver cells. 2. The effects of...Full Text Available

1980-03-15

463

The comparative uptake and interaction of several radionuclides in the trophic levels surrounding the Los Alamos Meson Physics Facility (LAMPF) waste water ponds

A study was undertaken to examine the uptake, distribution, and interaction of five activation products (Co-57, Be-7, Cs-134, Rb-83, and Mn-54) within the biotic and abiotic components surrounding the waste treatment lagoons of the Los Alamos Meson Physics Facility (LAMPF). The study attempted to ascertain where, and what specific interactions were taking place among the isotopes and the biotic/abiotic components. A statistical approach, utilizing Multivariate Analysis of Variance (MANOVA), was conducted testing the radioisotopic concentrations by (1) the trophic levels (TROPLVL) in each position sampled on the grid, (2) where sampled on the grid (TRAN), (3) where sampled with-in each grid line (PLOT), and (4) the side with which sampled (SIDE). This provided both the dependent and independent variables that would be tested. The Null Hypothesis (Ho) tested the difference in the mean values of the isotopes within/between each of the four independent variables. The Rb-83 statistic ...

1983-05-01

464

Silicon nanopowder as active material for hybrid electrodes of lithium-ion batteries

A study was undertaken to examine the uptake, distribution, and interaction of five activation products (Co-57, Be-7, Cs-134, Rb-83, and Mn-54) within the biotic and abiotic components surrounding the waste treatment lagoons of the Los Alamos Meson Physics Facility (LAMPF). The study attempted to ascertain where, and what specific interactions were taking place among the isotopes and the biotic/abiotic components. A statistical approach, utilizing Multivariate Analysis of Variance (MANOVA), was conducted testing the radioisotopic concentrations by (1) the trophic levels (TROPLVL) in each position sampled on the grid, (2) where sampled on the grid (TRAN), (3) where sampled with-in each grid line (PLOT), and (4) the side with which sampled (SIDE). This provided both the dependent and independent variables that would be tested. The Null Hypothesis (Ho) tested the difference in the mean values of the isotopes within/between each of the four independent variables. The Rb-83 statistic ...

1989-08-01

465

British Library Electronic Table of Contents (United Kingdom)

Cycling parameters (reversible specific capacity, first-cycle coulombic efficiency, accumulated irreversible capacity, and reversible capacity retention) of hybrid electrodes based on mechanical mixtures of a silicon nanopowder with KS6 and MAG-20 synthetic graphites and binders of varied nature were subjected to an integrated analysis in comparison with graphite electrodes.

2011-01-01

466

Scattered radiation effect on the defect image in high-energy bremsstrahlung introscopy

Regulation of K⁺ Influx in Barley 1

Results of the evaluation of the scattered radiation effect on the image of defects in examined products are given. The formula is suggested which characterizes the image of defects on a scintillation screen as well as accumulation factors are calculated by the Monte-Carlo method. Values of fluctuations of absorbed energy in the screen used for the evaluation of sensitivity are experimentally obtained. The effect of high-energy bremsstrahlung on the defect detection is analyzed.

467

Regulation of Indole-3-Acetic Acid Biosynthetic Pathways in Carrot Cell Cultures ¹

Influx and accumulation of K⁺ in barley (Hordeum vulgare L. cv Fergus) roots were measured at two temperatures (10°C and 20°C) in plants which had been grown...Full Text Available

1984-03-01

468

Reducing Rice Seed Storage Protein Accumulation Leads to Changes in Nutrient Quality and Storage Organelle Formation¹^[W]^[OA]

2,4-Dichlorophenoxyacetic acid (2,4-D) promotes the accumulation of tryptophan-derived indole-3-acetic acid (IAA) in carrot cell cultures during callus proliferation by a biosynthetic pathway that is...Full Text Available

1992-11-01

469

Radon transport in an activated charcoal canister

Rice (Oryza sativa) seed storage proteins (SSPs) are synthesized and deposited in storage organelles in the endosperm during seed maturation as a nitrogen source for germinating seedlings....Full Text Available

2010-12-01

470

Preliminary studies in sheep exposed to "8"5Kr atmospheres

The transport of Rn through activated charcoal was modelled for a charcoal canister used for surface emanation measurements. Derived Rn concentration distributions in full and half charcoal charges were compared with measured Rn profiles. The distributions were also compared with an empirical expression for the measured profiles. Close agreement was observed between the measured, empirically generated and derived profiles. The influence of temperature and humidity on Rn accumulation and transport is also discussed.

1989-02-01

471

Potential U.S. contributions to in-reactor experiments for fast reactor surveillance systems

Accumulation of "8"5Kr in arterial blood of sheep occurs within 10 min of inhalation exposure initiation, and disappears by 30 min after exposure termination. As reported for other species, "8"5Kr concentrations in fat were approximately 10 times those in other tissues.

1977-05-01

472

PWR steam generator chemical cleaning process

It is maintained that special features of FFTF make it an ideal system to test sodium boiling detection techniques by acoustic/neutronic methods and to test the response of acoustic/neutronic sensors to vibrations. It is shown that accumulated research results indicate that such tests in FFTF are feasible, predictable, promising and safe. (author).

473

Molecular and functional characterization of a novel chromoplast-specific lycopene ?-cyclase from Citrus and its relation to lycopene accumulation

Some of the origins of corrosion encountered in the secondary side of pressurized water reactor steam generators are:-sludge accumulation (a mixture of metal oxides, primarily magnetite and copper) on tube sheet and attack of tube support plates by aggressive impurities leading to denting. Although Electricite de France has not suffered from these problems, it has developed a chemical cleaning process to dissolve corrosion products at both locations. (author).

1986-10-13

474

Modified accumulator method for measuring surface radon flux from a uranium tailings pile

Carotenoids are the main pigments responsible of the colouration of Citrus fruits. The β-cyclization of lycopene, catalysed by the lycopene β-cyclases (β-LCY),...Full Text Available

2009-04-01

475

Metabolism and Synthesis of Indole-3-Acetic Acid (IAA) in Zea mays (Levels of IAA during Kernel Development and the Use of in Vitro Endosperm Systems for Studying IAA Biosynthesis).

A modified accumulator was devised to measure surface radon flux from porous media. It consists of a collector hood accumulator with a homogenizer pump and a pressure balancer. The latter was used to compensate for any pressure changes produced during sample withdrawl and hence eliminate additional radon transport from media. Errors resulting from radon back diffusion due to decreasing concentration gradient with time across the interface were eliminated by measuring radon concentrations in the accumulator for two different periods of time and calculating the true radon flux, J(o), from the solution of a time-dependent radon transport equation. Core samples from the observation site were withdrawn for laboratory determination of porosity, moisture content, bulk and grain densities, Ra-226 source concentration and the fraction of Rn-222 produced in the void volume. The data were used to calculate the radon diffusion ...

1982-07-01

476

Late effects of inhaled Pu(NO_3)_4 in rats

Kernels of Zea mays on an intact plant accumulate indole-3-acetic acid (IAA) at the rate of 190 ng g-1 fresh weight h-1. Of the IAA synthesized, 97% is in the esterified form and less than 3% remains...Full Text Available

1994-09-01

477

Kinetic energy accumulators. Application to electric cars

Rats that inhaled "2"3"9Pu(NO_3)_4 or "2"3"8Pu(NO_3)_4 developed lung tumors and bone tumors. Lung tumors were clearly associated with Pu inhalation (accumulated dose to lung, 1 rad to 5000 rads); bone tumors could not be unequivocally related to the radiation insult.

1977-05-01

478

Integrating Phytoextraction and Biofortification: Fungal Accumulation of Selenium in Plant Materials from Phytoremediation of Agricultural Drainage

The development of electric cars always met with the difficulty in storing energy and in recovering it in the form of electric power. Research work done for the last two decades in the field of materials and of new technologies oriented mainly towards aeronautical and space applications have led to designing, realizing and experimenting with flywheels rotating at high speed in magnetic bearings. The results obtained represent openings that, now, fall in with different industrial fields and in particular with application to electric cars.

1982-12-01

479

Insect-Induced Conifer Defense. White Pine Weevil and Methyl Jasmonate Induce Traumatic Resinosis, de Novo Formed Volatile Emissions, and Accumulation of Terpenoid Synthase and Putative Octadecanoid Pathway Transcripts in Sitka Spruce1[w

The phytomanagement of Se-polluted soil and water is one strategy that may be environmentally sustainable and cost-effective for soils and waters enriched with natural-occurring Se. Several plant species, including Indian mustard (Brassica juncea), pickleweed (Salicornia bigelovii), and other salt/S...

480

Identification of Thlaspi caerulescens Genes That May Be Involved in Heavy Metal Hyperaccumulation and Tolerance. Characterization of a Novel Heavy Metal Transporting ATPase1

Stem-boring insects and methyl jasmonate (MeJA) are thought to induce similar complex chemical and anatomical defenses in conifers. To compare insect- and MeJA-induced terpenoid responses, we analyzed...Full Text Available

2005-01-01

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481

High Levels of Tryptamine Accumulation in Transgenic Tobacco Expressing Tryptophan Decarboxylase ¹

Thlaspi caerulescens is a heavy metal hyperaccumulator plant species that is able to accumulate extremely high levels of zinc (Zn) and cadmium (Cd) in its shoots (30,000 μg...Full Text Available

2004-11-01

482

Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-? and matrix metalloproteinase-13 in human chondrocytes

A full-length complementary DNA clone encoding tryptophan decarboxylase (TDC; EC 4.1.1.28) from Catharanthus roseus (De Luca V, Marineau C, Brisson N [1989] Proc Natl Acad Sci USA 86:...Full Text Available

1990-11-01

483

GM mosquito wild release takes campaigners by surprise - SciDev.Net

IntroductionThe major risk factor for osteoarthritis (OA) is aging, but the mechanisms underlying this risk are only partly understood. Age-related accumulation of advanced glycation...Full Text Available

2009-01-01

484

GM Mosquito Wild Release Takes Campaigners by Surprise

... The male GM mosquitoes mate with normal females to produce larvae that die unless the antibiotic tetracycline is present. In tetracycline's absence an enzyme accumulates to a toxic level, killing the larvae. The developers hope the strategy could be combined with other mosquito control methods to reduce transmission in dengue-prone areas. Ricarda Steinbrecher, a geneticist and co-director of EcoNexus -a UK-based non-profit research organisation -expressed surprise ...

485

Features of laser damage to elastic polymers

... The male GM mosquitoes mate with normal females to produce larvae that die unless the antibiotic tetracycline is present. In tetracycline's absence an enzyme accumulates to a toxic level, killing the larvae. The developers hope the strategy could be combined with other mosquito control methods to reduce transmission in dengue-prone areas. Ricarda Steinbrecher, a geneticist and co-director of EcoNexus - a UK-based non-profit research organization - ...

486

Efficiency of preliminary transmutation of actinides before ultimate storage

Threshold pump intensity values leading to irreversible damage to colored laser elements based on elastic polymers were measured. The damage to colored elastomers is connected with absorbing microinclusions but is independent of molecular absorption. It is shown that damage to the elastomers has a pronounced threshold character in contrast to the microdamage accumulation effect in glassy polymers. The damage threshold for elastomers is 1.5 times higher, which is connected with the absence of microstresses (characteristics for organic glasses) in the specimens. 13 references.

1988-03-01

487

Effects of low-level radiation upon the hematopoietic steam cell: implications for leukemogenesis

The concept of preliminary transmutation of minor actinides before placement to the long-term storage is considered. The purpose of such preliminary transmutation before ultimate storage is to incinerate a part of actinides and to transform another part into new actinides providing low level of radiotoxicity accumulated in the storage. Modes of transmutation in reactors of PWR, PHWR (CANDU), and Superfenix types are compared. Among power reactors, heavy-water PHWR type reactor is most acceptable for preliminary transmutation. (author)

2003-04-20

488

Effect of polychlorinated biphenyls (Aroclor 1254) on rhythmic pituitary-adrenal function. [Rats

These studies have addressed firstly the effect of single small doses of x-ray upon murine hematopoietic stem cells to obtain a better estimate of the D/sub q/. It is small, of the order of 20 rads. Secondly, a dose fractionation schedule tht does not kill or perturb the kinetics of hemopoietic cell proliferation was sought in order to investigate the leukemogenic potential of low level radiation upon an unperturbed hemopoietic system. The studies reported herein show tht 1.25 rads every other day decrease the CFU-S content of bone marrow by the time 40 rads are accumulated. Studies on the effect of 0.5, 1.0, 2.0, and 3.0 rads 3 times per week are under way. Two rads 3 times per week produced a modest decrease in CFU-S content of bone marrow after an accumulation of 68 rads. With 3.0 rads 3 times per week an accumulation of 102 rads produces a significant decrease in CFU-S content of bone marrow. Dose fractionation at 0.5 ...

1983-01-01

489

Digitonin abolishes free 2-deoxy-D-glucose accumulation in isolated rat adipocytes

Numerous studies have documented the general toxicity of the polychlorinated biphenyls (PCBs) and a sizeable literature has accumulated concerning the toxic effects of PCBs on a variety of homeostatic systems. However, current information regarding the effects of PCBs on rhythmic endocrine function is quite limited. Thus, the present study was undertaken to determine whether circadian periodicity in pituitary-adrenal function is affected by exposure to PCBs.

1983-09-01

490

Determination of cesium and selenium in cultivated mushrooms using radionuclide X-ray fluorescence technique

The hypothesis that accumulation against sizable chemical gradients of free (non-phosphorylated) 2-deoxy-D-glucose (2dGlc) in isolated rat adipocytes results from an intracellular compartmentation of free hexose was investigated. Cells exposed to 20 ..mu..g/ml digitonin for 10' demonstrated an increased plasma membrane permeability indexed by increased L-glucose entry rates and cellular (presumably cytosolic) protein and K/sup +/ loss. Functional integrity of intracellular organelles was indicated by the ability of the cells to support ATP-driven /sup 45/Ca/sup 2 +/-uptake. Equilibrium 3-O-methylglucose (3-O-MG, a non-accumulated hexose) levels were unaffected. These data suggest a specific permeabilizing action of digitonin at the plasma membrane having no effect on intracellular organelles or passively distributed solutes. Upon addition of digitonin, free 2dGlc fell from 66.5 +/- 8.9 to 7.4 +/- 2.3 pmol/10/sup 5/ cells, a value not ...

1986-03-05

491

Detection of acute myocardial infarction in spontaneously hypertensive rats by /sup 99m/Tc-Pyrrolidino methyl tetracycline

Cesium and selenium intake of cultivated mushrooms (Agaricus bisporus), with these elements previously added to culture medium, has been examined from the viewpoint of health- and environmental protection. The process of measuring has been carried out by the radionuclide X-ray fluorescence technique. Treatments of the elementary substance with Se salt appears to influence the Se content of the mushrooms to a significant extent. Cs intake is of considerable importance, as this element is accumulated by mushrooms. (author)

2000-09-01

492

Compensation for a Mutated Auxin Biosynthesis Gene of Agrobacterium Ti Plasmid A66 in Nicotiana glutinosa Does Not Result from Increased Auxin Accumulation ¹

The myocardial infarct induced by isoproterenol in spontaneously hypertensive rats accumulates higher activities of /sup 99/sup(m)Tc-PM tetracycline compared with the cardiac infarct in normotensive rats caused by the same method. The isoproterenol model of the myocardial necrosis was induced in intact rats without opening the thorax and is a convenient method for experimental radioisotope studies.

1983-01-01

493

Coal geology and its application to coal-bed methane reservoirs

Nicotiana glutinosa compensated for a mutated tumor-morphology-shooty (tms) (auxin biosynthesis) locus of Agrobacterlum tumefaciens strain A66 and...Full Text Available

1989-04-01

494

A total of nine papers were presented at the course with the following titles: peat accumulation and coal basins; coal composition; coal quality; sedimentary environments of coal; generation, storage and migration of natural gas in coal bed reservoirs; geophysical log interpretation; the Ardley coal zone of central Alberta; stratigraphy and sedimentary environment of the Coalspur Formation; and the coal-bearing Luscar Group of western Alberta. All of these papers have been abstracted separately.

1990-01-01

495

Coal bibliography

Clinical use of lipiodol in hepatic arteriography

This report contains basic bibliographic data for reports held by Resource Management and Mining (Ministry of Energy) in its Coal Technical Information System (CTIS). This system contains a large number of published and unpublished reports relating to New Zealand's coal, peat, and oil shale resources. This material has been accumulated from a wide range of sources and is of widely varying quality.

1987-01-01

496

Base-level cycles and episodic coal accumulation - case study of Dongsheng coalfield in Ordos basin

Lipiodol, lipid soluble contrast media, was applied to 59 patients, who was clinically suspected to have hepatic tumor, in the Department of Diagnostic Radiology, Seoul National University Hospital. The results of the clinical use of Lipiodol were as follows: 1. The clinical diagnosis was hepatocellular carcinoma (HCC) in 50 cases, cavernous hemangioma in 4 cases, metastasis in one case and others in 4 cases. 2. After hepatic arteriography, Lipiodol only was injected in 28 cases, mixture of Lipiodol and Mitomycin was injected in 22 cases and transcatheter arterial embolization was performed additionally after injection of Lipiodol and Mitomycin in 9 cases. 3. Among the 50 cases of HCC, Lipiodol was accumulated in the lesion in 49 cases. However, similar accumulation of Lipiodol occured in a metastatic cancer and cavernous hemangiomas. 4. Plain radiographic patterns of Lipiodol accumulation could be divided into fine ...

1986-08-15

497

Abundance of Alnus incana ssp. rugosa in Adirondack Mountain shrub wetlands and its influence on inorganic nitrogen

The advantage of high-resolution sequence stratigraphy, which takes base-levels as reference, is that it can be applied to continental depositional basins controlled by multiple factors and can effectively improve the accuracy and resolution of sequential stratigraphic analysis. Moreover, the principles of base-level cycles are also suitable for analyzing sequential stratigraphy in continental coal-bearing basins because of their accuracy in forecasting distribution of coal measures. By taking the Dongsheng coalfield in the Ordos basin as an example, the extensive application of base-level cycles in exploration and exploitation of coal is analyzed. The result shows that the Yan'an formation in the Dongsheng area is a long-term base-level cycle which is bordered by nonconformities and made up of five mid-term cycles and 13 short-term cycles. The long-term cycle and the mid-term cycles are obvious in comparison with a transverse profile. The episodic coal ...

2006-12-15

498

A modified accumulator method for measuring surface radon flux from a uranium tailings pile

The presence of the nitrogen-fixing shrub, Alnus incana ssp. rugosa, influences the concentration of inorganic nitrogen in surface waters in the Adirondack Mountain region of northern New York. - The purpose of this research was to determine the abundance of the nitrogen-fixing shrub, Alnus incana ssp. rugosa (speckled alder), in shrub wetlands of the Adirondack Mountain region of New York State and to determine whether its abundance affects the concentration or accumulation of inorganic nitrogen in wetland substrates. Alder/willow wetlands are the second most common wetland type in the Adirondack region. The Adirondack Park Agency's digital GIS database of wetland types was used to determine the areal extent of alder/willow wetlands in the Adirondacks. Randomly selected wetlands were sampled to determine the size and abundance of alder. Alder densities averaged {approx}7000 stems ha{sup -1} and alder was present in 75% of the wetlands. As an indication of ...

2003-06-01

499

A mast cell secretagogue, compound 48/80, prevents the accumulation of hyaluronan in lung tissue injured by ionizing irradiation

A modified accumulator was devised to measure surface radon flux from porous media. It consists of a collector hood accumulator with a homogenizer pump and a pressure balancer. The latter was used to compensate for any pressure changes produced during sample withdrawl and hence eliminate additional radon transport from media. Errors resulting from radon back diffusion due to decreasing concentration gradient with time across the interface were eliminated by measuring radon concentrations in the accumulator for two different periods of time and calculating the true radon flux, J(o), from the solution of a time-dependent radon transport equation. Core samples from the observation site were withdrawn for laboratory determination of pkrosity, moisture content, bulk and grain densities, Ra-226 source concentration and the fraction of Rn-222 produced in the void volume. The data were used to calculate the radon diffusion ...

500