WorldWideScience
1

Cardiovascular Safety of Degarelix: Results From a 12-Month, Comparative, Randomized, Open Label, Parallel Group Phase III Trial in Patients With Prostate Cancer  

UK PubMed Central (United Kingdom)

PurposeWe assessed the cardiovascular safety profile of degarelix, a new gonadotropin-releasing hormone antagonist.Materials...Full Text Available

2010-12-01

3

Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects  

UK PubMed Central (United Kingdom)

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

4

Pharmacokinetics and tolerability of zibotentan (ZD4054) in subjects with hepatic or renal impairment: two open-label comparative studies  

UK PubMed Central (United Kingdom)

BackgroundZibotentan (ZD4054) is a specific endothelin A (ETA) receptor antagonist being investigated for the treatment of prostate cancer. As zibotentan is eliminated...Full Text Available

5

Intravenous immunoglobulin in the treatment of primary trigeminal neuralgia refractory to carbamazepine: a study protocol[ISRCTN33042138  

UK PubMed Central (United Kingdom)

BackgroundWe have recently reported successful treatment of patients with chronic pain syndromes using human pooled intravenous immunoglobulin (IVIG) in a prospective, open-label...Full Text Available

7

Lapses following Alcohol Treatment: Modeling the Falls From the Wagon*  

UK PubMed Central (United Kingdom)

ObjectiveThis study investigated transitions between drinking and nondrinking during the first 12 months following treatment and whether transitions in posttreatment...Full Text Available

2008-07-01

8

Efficacy and Safety of Galantamine in Patients with Dementia with Lewy Bodies: A 24-Week Open-Label Study  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background: Dementia with Lewy bodies (DLB) is a common dementia of the elderly. A significant cholinergic deficit has been demonstrated that may be responsive to treatment by cholinesterase inhibitors (ChEIs). Methods: A 24-week, open-label study was designed to assess the efficacy and safety of a ChEI, galantamine, in 50 patients with DLB. Results: This study showed beneficial effects with galantamine in 2 of the 3 primary efficacy parameters. The scores on the Neuropsychiatric Inventory (NPI-12) improved by 8.24 points from baseline (p = 0.01) especially in visual hallucinations and nighttime behaviors (p = 0.004). The scores on the Clinician's Global Impression of Change improved by 0.5 points from baseline (p = 0.01). The third primary efficacy parameter, the Cognitive Drug R...

2007-01-01

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Mirtazapine for patients with alcohol dependence and comorbid depressive disorders: A multicentre, open label study  

British Library Electronic Table of Contents (United Kingdom)

Major depressive disorder and alcohol dependence are common and serious mental illnesses. There is a great interest in discovering useful treatments for both mood symptoms and alcohol abuse in those patients with depressive disorders and comorbid alcohol dependence. The primary purpose of this study was to evaluate the effectiveness and tolerability of mirtazapine for the treatment of patients with alcohol dependence comorbid with a depressive disorder in an open label, naturalistic multicentre treatment setting. The 17-item Hamilton Depression Rating Scale (HDRS), the Hamilton Anxiety Rating Scale (HARS) and the Clinical Global Impression-Severity (CGI-S) scale were measured at baseline and at weeks 4 and 8 for the assessment of treatment effectiveness. Alcohol craving was measured using ...

2006-01-01

10

Stability of Combat Exposure Recall in Operation Iraqi Freedom Veterans  

British Library Electronic Table of Contents (United Kingdom)

PurposeThis study evaluates changes in recall of combat exposures over the first year after return from deployment. The research purpose is to assess whether recall of combat exposures is consistent at different time points; if not, what demographic and/or PTSD symptom risk factors exist for any directional instability. MethodsSurveys completed by soldiers at 3, 6, and 12 months post-Operation Iraqi Freedom (OIF) deployment were linked for longitudinal analysis in a previous study in which three matched datasets were created: 3-6 months (N = 768), 6-12 months (N = 341), and 3-12 months (N = 445). Post-traumatic stress disorder (PTSD) was assessed by using the National Center for PTSD Checklist. The reliability of recall for 36 combat exposures was quantified. The effects of demographics an...

2010-01-01

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Predictive value of bronchoalveolar lavage cell analysis in sarcoidosis.  

UK PubMed Central (United Kingdom)

Patients with histopathologically proved sarcoidosis were studied serially by means of bronchoalveolar lavage, initially at the time of diagnosis and then six and 12 months later. Two years later they...Full Text Available

1988-04-01

12

Electrical Discharge Machining (EDM) Gun Barrel Bore and Rifling Feasibility Study.  

Science.gov (United States)

A 12-month program was conducted to advance the technology of the Electrical Discharge Machining (EDM) process to be applicable to the stringent requirements of gun barrel boring and rifling. The type of barrels employed in the test were .220 swift gun ba...

1974-01-01

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A School-Based Exercise Intervention Program Increases Muscle Strength in Prepubertal Boys  

UK PubMed Central (United Kingdom)

This prospective controlled intervention study over 12 months evaluated the effect of exercise on muscular function, physical ability, and body composition in pre-pubertal boys. Sixty-eight boys aged...Full Text Available

2010-01-01

14

Percutaneous osseointegrated prostheses for amputees: Limb compensation in a 12-month ovine model.  

Science.gov (United States)

Percutaneous osseointegrated prostheses are being investigated as an alternative strategy to attach prosthetic limbs to patients. Although the use of these implants has shown to be promising in clinical trials, the ability to maintain a skin seal around an osseointegrated implant interface is a major challenge to prevent superficial and deep periprosthetic infections. The specific aim of this study was to establish a translational load-bearing ovine model to assess postoperative limb compensation and gait symmetry following a percutaneous osseointegrated implant. We tested the following hypotheses: (1) the animals would return to pre-amputation limb loads within 12-months; (2) the animals would return to a symmetrical gait pattern (stride length and time in stance) within 12-months. The results demonstrated that one month following surgery, the sheep loaded their amputated limb to a ...

2011-09-13

15

Combination adjuvant chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin after liver transplantation for hepatocellular carcinoma: a preliminary open-label study  

British Library Electronic Table of Contents (United Kingdom)

Summary The purpose of this study was to evaluate the efficacy of postoperative adjuvant chemotherapy with FOLFOX regimen on the outcome after LT for HCC patients who did not meet the Milan criteria. Ninety-five consecutive HCC patients with liver cirrhosis undergoing LT were enrolled. Fifty-eight who did not meet the Milan criteria were randomized to open-label treatment with or without adjuvant chemotherapy after LT (n?=?29/group). The FOLFOX chemotherapy protocol comprised 3-week cycles of oxaliplatin 100?mg/m2 on day 1, leucovorin (calcium folinate, CF) 200?mg/m2 on day 1 followed by 3-day, and 5-fluorouracil (5-FU) 2000?mg/m2 as a 48-h continuous infusion, for up to six courses in the 1st year after transplantation. Median survival was extended by 4.57?months by combination chemothera...

2011-01-01

16

An open-label study of naltrexone and bupropion combination therapy for smoking cessation in overweight and obese subjects  

British Library Electronic Table of Contents (United Kingdom)

A combination of sustained release (SR) naltrexone (32mg/day) and bupropion SR (360mg/day) plus behavioral counseling was evaluated for the treatment of smoking cessation and mitigation of nicotine withdrawal and weight gain. Thirty overweight or obese nicotine-dependent subjects were enrolled in a 24-week, open-label study; 85% and 63% completed 12 and 24weeks, respectively. The target quit date was Week 4. Week 4-12 continuous abstinence rate was 48%, 78% of subjects achieved CO 10ppm, serum cotinine decreased from 185 to 48mg/L, and tobacco use decreased from 129 to 14 cigarettes/week. Similar results were seen at Week 24. Body weight was essentially unchanged (Week 12: -0.1%; Week 24: +0.4%). Except for a transient significant increase 1week after the target quit date (p<0.05), nicotin...

2010-01-01

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2000-centiGray total lymphoid irradiation for refractory rheumatoid arthritis  

International Nuclear Information System (INIS)

Because toxicity with the use of 3000 centiGray (cGy) of total lymphoid irradiation (TLI) was observed in an earlier study, 2000-cGy treatments were delivered in a 2-portal format to 7 patients and in a modified 3-portal fashion to 6 patients, as part of a randomized, investigator-blinded trial of TLI treatment for refractory rheumatoid arthritis. Analysis of combined data from the 13 patients revealed statistically significant improvement in 5 clinical indicators of disease activity at the end of TLI and 6 and 12 months later, accompanied by T4-specific immunosuppression. Management considerations resulted in the introduction of prednisone therapy in 5 patients, methotrexate in 4, and azathioprine in 1 during the interval of 8-12 months post-TLI. Herpes zoster occurred in 5 patients prior to the initiation of this additional therapy. These data indicate that, in patients with ...

18

12-month follow-up of first-episode psychosis in Finland and Spain-differential significance of social adjustment-related variables  

British Library Electronic Table of Contents (United Kingdom)

Abstract Objective:- This study explored 12-month outcome and its associations to social adjustment-related variables in patients with first-episode non-affective psychosis in Finland and Spain. Methods:- Forty-nine Finnish and 37 Spanish patients were evaluated at admission on various characteristics of social adjustment. Outcome was measured for 68 (79%) patients by the Brief Psychiatric Rating Scale, Global Assessment Scale, and Grip on Life. Results:- One-fourth of the patients experienced psychotic symptoms at follow-up. Sixty per-cent of the patients showed good global functioning and Grip on Life. In both patient groups, poor earlier global functioning, weak social network, poor Grip on Life, and psychological dependence on family of origin were associated with poor outcome. In the ...

2011-01-01

19

Combination of physiologically balanced growth factors with antioxidants for reversal of facial photodamage  

British Library Electronic Table of Contents (United Kingdom)

Abstract A 3-month, open-label, single-center study was conducted to determine whether a uniquely formulated and physiologically balanced topical treatment serum containing multiple growth factors, cytokines, peptides, antioxidants and depigmenting agents could improve the visible signs of facial photodamage. Thirty-seven females, aged 32-55 years, with mild to severe, fine and coarse peri-ocular wrinkles were enrolled and completed the study. Subjects applied the treatment serum to the face twice daily for 3 months in conjunction with a basic skincare regimen. Clinical evaluations of photodamage were performed at baseline and months 1, 2 and 3. Cutometer measurements and subject self-assessment questionnaires were also conducted during the study. Clinical evaluations showed statistically ...

2010-01-01

20

A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing  

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to observe both the clinical signs and symptoms of wounds at risk of infection, that is critically colonised (biofilm infected) and antimicrobial-performance of an ionic silver alginate/carboxymethylcellulose (SACMC) dressing, in comparison with a non silver calcium alginate fibre (AF) dressing, on chronic venous leg and pressure ulcers. Thirty-six patients with venous or pressure ulcers, considered clinically to be critically colonised (biofilm infected), were randomly chosen to receive either an SACMC dressing or a non silver calcium AF dressing. The efficacy of each wound dressing was evaluated over a 4-week period. The primary study endpoints were prevention of infection and progression to wound healing. The SACMC group showed a statistically significant (P = ...

2010-01-01

21

Pentoxyphylline in association with vitamin E reduces cutaneous fibrosis in systemic sclerosis  

British Library Electronic Table of Contents (United Kingdom)

Systemic sclerosis (SSc) is a disorder characterized by skin thickness and vasculopathy. The objective of the study was to evaluate the therapeutic effect and safety of the association of pentoxyphylline and vitamin E in SSc patients. Twelve SSc patients (American College of Rheumatology criteria) enrolled this 24-week open-label study. Patients received daily 800?mg of pentoxyphylline and 800?UI of vitamin E and were evaluated at 4-week interval. The primary efficacy endpoint was the change in Modified Rodnan Skin Score (MRSS) at week 24. Nine diffuse SSc patients treated 6?months with cyclophosphamide were used as a historical control group. The mean age of the treated group was 43.6?years, and ten of 12 (84%) patients were women. Their mean MRSS reduced from 25.7 to 18.7 (p?=?0.03) at 1...

2009-01-01

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A multifactorial strategy of pain management is associated with less pain in scheduled vaccination of children. A study realized by family practitioners in 239 children aged 4-12 years old  

British Library Electronic Table of Contents (United Kingdom)

Background and aims. The multiplicity of vaccine injections during childhood leads to iterative painful and stressful experiences which may lead in turn to anticipated pain and then possibly to a true needle phobia. We aimed at evaluating a multifactorial strategy of pain management combining pharmacological and non-pharmacological approaches during vaccination, as compared to usual care, in 4- to 12-year-old children. Methods. In all, 239 children were enroled by 25 family practitioners in an open-label study. After a pseudo-randomization, usual pain management (n = 132) was compared to a multifactorial strategy (n = 107) associating preliminary application of an anesthesic patch, preferential use of specified vaccines, child education by the parents and the doctor, parental accompaniment...

2008-01-01

23

Effect of nonsteroidal anti-inflammatory drug plasters for knee osteoarthritis in Japanese: a randomized controlled trial  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to examine the effect of a nonsteroidal anti-inflammatory drug (NSAID) plaster for knee osteoarthritis among Japanese patients. An open-labeled, randomized, controlled, multiclinic trial was performed involving outpatient clinic groups. Two comparative groups?plaster NSAIDs and oral NSAIDs?were randomly allocated. The drugs used were limited to the current top three in both groups in Japan. Treatments were assessed after four?weeks and compared with the baseline scores. Outcomes were evaluated by two psychometric measures: Japanese knee osteoarthritis measure, and pain with the visual analogue scale. The total number of patients included in the final evaluation was 165 (87 for the plaster group and 78 for the oral group). Between these two groups there were ...

2010-01-01

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A 24-week, multicentre, open evaluation of the clinical effectiveness of the rivastigmine patch in patients with probable Alzheimer-s disease  

British Library Electronic Table of Contents (United Kingdom)

Summary Background:- Cholinesterase inhibitors form the mainstay of treatment for persons with mild-to-moderate Alzheimer-s disease (AD). The rivastigmine patch may increase compliance and the proportion of patients maintaining an efficacious dose compared with oral cholinesterase inhibitors. Objective:- To investigate the proportion of patients who reached and maintained the target rivastigmine patch dose compared with the target rivastigmine capsule dose reported in clinical trials. Methods:- This was a multicentre, 24-week, open-label study in persons with probable AD and a Mini-Mental State Examination (MMSE) score of --10 and --26. The primary outcome was the proportion of patients (ITT population) treated with 9.5-mg/24-h rivastigmine patch for at least 8-weeks at week 24. Secondary ...

2011-01-01

25

Advances in Old-Fashioned Heterotic String Model Building  

CERN Document Server

I review findings of various research groups regarding perturbative heterotic string model building in the last 12 months. Attention is given to recent studies of extra U(1)'s and local discrete symmetries (LDS's) in generic string models. Issues covered include the role of U(1)'s and LDS's in limiting proton decay, developments in classification of models containing anomalous U(1), and possible complications resulting from kinetic mixing between observable and hidden sector U(1)'s. Additionally, recent string-derived and string-inspired models are briefly reviewed. Talk Presented at SUSY '97.

1998-01-01

26

Photorefractive keratectomy with mitomycin-C after corneal transplantation for keratoconus  

British Library Electronic Table of Contents (United Kingdom)

PurposeTo evaluate the efficacy of photorefractive keratectomy (PRK) for residual refractive error after penetrating keratoplasty (PKP) for keratoconus. SettingPrivate ophthalmic clinic. DesignCase series. MethodConsecutive patients who had PRK augmented with topical mitomycin-C (MMC) after PKP for keratoconus were retrospectively reviewed. Patients were divided into a a low cylinder group (refractive cylinder 6.00 D). Visual acuity, refraction, and keratometry were analyzed preoperatively and 1, 3, 6, and 12 months postoperatively. ResultsThe study comprised 47 eyes (41 patients). The spherical equivalent (SE) decreased from -4.24 D +- 3.23 (SD) preoperatively to -0.71 +- 1.03 D 12 months postoperatively in the low cylinder group and from -4.19 +- 3.54 D to -2.45 +- 3.42 D, respectively, ...

2011-01-01

27

A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing.  

Science.gov (United States)

The aim of this study was to observe both the clinical signs and symptoms of wounds at risk of infection, that is critically colonised (biofilm infected) and antimicrobial-performance of an ionic silver alginate/carboxymethylcellulose (SACMC) dressing, in comparison with a non silver calcium alginate fibre (AF) dressing, on chronic venous leg and pressure ulcers. Thirty-six patients with venous or pressure ulcers, considered clinically to be critically colonised (biofilm infected), were randomly chosen to receive either an SACMC dressing or a non silver calcium AF dressing. The efficacy of each wound dressing was evaluated over a 4-week period. The primary study endpoints were prevention of infection and progression to wound healing. The SACMC group showed a statistically significant (P = 0.017) improvement to healing as indicated by a reduction in the surface area of the wound, over the 4-week study period, compared with ...

2010-05-31

28

Use of morphine sulfate (MS Contin) in patients with burns: a pilot study.  

Science.gov (United States)

Morphine sulfate (MS Contin), a proven analgesic in the treatment of cancer pain and chronic benign pain, seems to be a good analgesic for the treatment of burn pain. MS Contin is morphine sulfate incorporated in a wax cellulose matrix delivery system. This wax cellulose delivery system gives MS Contin its duration of action. Ten patients were enrolled in an open-labeled, nonrandomized study. The study was designed to examine the analgesic efficacy of MS Contin in the burn population. Each patient remained in the study for 6 days. The efficacy of the analgesic regimen was subjectively measured by the visual pain scale. The MS Contin group was retrospectively compared with a group of patients who were given continuous intravenous infusions of morphine. The two groups were matched according to age, burn size, surgical procedures, and hospital stay. The analgesic qualities of MS Contin were comparable to ...

29

The SPIRIT V Study:A Clinical Evaluation of the XIENCE V Everolimus-Eluting Coronary Stent System in the Treatment of Patients With De Novo Coronary Artery Lesions  

British Library Electronic Table of Contents (United Kingdom)

ObjectivesThe SPIRIT V (A Clinical Evaluation of the XIENCE V Everolimus-Eluting Coronary Stent System in the Treatment of Patients With De Novo Coronary Artery Lesions) study is a post-market surveillance experience of the XIENCE V (Abbott Vascular, Santa Clara, California) everolimus-eluting stent (EES) in patients with higher-risk coronary anatomy. BackgroundPrevious pre-approval studies have shown the safety and efficacy of EES in highly selected groups of patients. MethodsThe SPIRIT V trial is a prospective, open label, single arm, multicenter study. Two thousand seven hundred patients with multiple de novo coronary artery lesions suitable for treatment with a planned maximum of 4 EES were enrolled at 93 centers in Europe, Asia Pacific, Canada, and South Africa. Lesions had a referenc...

2011-01-01

30

Logistics (contd.)  

Indian Academy of Sciences (India)

start within 6-12 months with small number of journals test and quality check with these journals already having full text sites ...

31

A phase 1 study of BMS-275183, a novel oral analogue of paclitaxel given on a daily schedule to patients with advanced malignancies  

British Library Electronic Table of Contents (United Kingdom)

Summary Purpose BMS-275183 is an oral C-4 methyl carbonate analogue of paclitaxel that has the same mechanism of action, stabilization of tubulin polymerization. The present study was designed to: (i) assess the safety and tolerability of BMS-275183, and (ii) determine a suitable Phase II dose of BMS-275183 when given on a continuous daily schedule to patients with advanced solid tumor(s). Methods This was a multi-institutional, open-label, Phase I, single-arm dose escalation study in which cohorts of eligible patients with advanced malignancies were treated with BMS-275183 orally on a continuous daily schedule. The starting dose level was 6?mg/m2/day administered once daily. Cohorts of 3 patients were treated at each dose level provided no dose-limiting toxicities (DLTs) were observed. Ea...

2011-01-01

32

Stability studies on refined soybean oil stored in various conditions  

International Nuclear Information System (INIS)

The 12 months stability study of freshly produced refined soybean oil revealed that refined soybean oil stored in plastic containers in dark was more hydrolytically and oxidatively stable than that stored in other containers in light condition. There was no significant difference at P < 0.05 in free fatty acids and acid value of oil stored under light and dark conditions in tin and glass containers but there was significant difference at P < 0.05 in peroxide value of oil stored in light and dark conditions in all the storage containers. Light increased the degree of oxidative rancidity of refined soybean oil, the most in tin containers, followed by glass containers and the least in plastic containers. (author)

2008-01-01

33

Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and bipolar spectrum disorders: Comprehensive review of prospective head-to-head and placebo-controlled comparisons  

British Library Electronic Table of Contents (United Kingdom)

Objective: To review data on efficacy and safety of second-generation antipsychotics (SGAs) in children and adolescents with psychotic and bipolar spectrum disorders. Methods: Medline/PubMed/Google Scholar search for studies comparing efficacy and/or tolerability: (i) between two or more SGAs; (ii) between SGAs and placebo; and (iii) between at least one SGA and one first-generation antipsychotic (FGA). The review focused on three major side-effect clusters: 1. body weight, body mass index, and cardiometabolic parameters, 2. prolactin levels, and 3. neuromotor side effects. Results: In total, 34 studies with 2719 children and adolescents were included. Studies lasted between 3weeks and 12months, with most studies (79.4%) lasting 3months or less. Nine studies (n=788) were conducted in patie...

2011-01-01

34

Studies on thermal degradation and termite resistant properties of chemically modified wood  

Energy Technology Data Exchange (ETDEWEB)

A series of experiments were carried out to examine the resistant capacity of a chemically treated hard wood, Anthocephalus cadamba (Roxb) Miq. to thermal and termite degradation. The treatment with thermosetting resins viz. urea formaldehyde (UF), melamine formaldehyde (MF) and phenol formaldehyde (PF) at 31-33 levels of weight percent gain (WPG) increased the strength property i.e. modulus of rupture (MOR) by 7.50-21.02% and stiffness i.e. modulus of elasticity (MOE) by 9.50-12.18% over the untreated one with no remarkable effect on specific gravity. The treated samples were found resistant to termite attack, while the untreated one was badly damaged by termites on 12 months' exposure to a termite colony. The thermal degradations of untreated and treated wood samples were studied using thermogravimetric (TGA) and differential thermogravimetric (DTG) techniques at heating rates 20 and 30 {sup o}Cmin{sup -1} in ...

2002-09-01

35

Real World Evaluation of Dual-Zone ICD and CRT-D Programming Compared to Single-Zone Programming: The ALTITUDE REDUCES Study  

British Library Electronic Table of Contents (United Kingdom)

Tachycardia Detection, ICD, CRT-D Devices, Appropriate and Inappropriate Shock.-Introduction: We evaluated the frequency of appropriate and inappropriate shocks and survival in patients using dual-zone programming versus single-zone programming. Methods and Results: For the ALTITUDE REDUCES study, patients were followed for 1.6 1.1 years. The 12-month incidence of any shock was lower for dual-versus single-zone programmed detection at rates -170 bpm and between 170-200 bpm (P < 0.001). Appropriate shock rates at 1 year were also lower with dual-zone programming in these rate intervals (single zone 9.1%, 5.4%, P < 0.001, dual zone 6.7%, 4.7%, P < 0.02). There were no detectable differences between single- and dual-zone shock incidence at detection rates - 200 bpm (P = 0.14). Inappropriate s...

2011-01-01

36

Adalimumab sustains steroid-free remission after 3-years of therapy for Crohn-s disease  

British Library Electronic Table of Contents (United Kingdom)

Summary Background- Treatments that achieve sustainable steroid-free clinical remission in Crohn-s disease are needed; however, long-term steroid-sparing efficacy data are limited. Aim- To evaluate steroid-sparing efficacy and the impact of steroid discontinuation on adverse events during treatment of Crohn's disease with adalimumab in the phase III randomised, double-blind 1-year CHARM trial and for an additional 2-years in its open-label extension ADHERE. Methods- Steroid-free remission and response and steroid-sparing (-50% steroid dose reduction) remission rates were evaluated over 3-years in patients who were taking corticosteroids at CHARM baseline. Results- Of 778 patients randomised in CHARM (including those who did not achieve clinical response to open-label induction therapy), 31...

2011-01-01

37

Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers.  

Science.gov (United States)

Vildagliptin is a potent and selective dipeptidyl peptidase IV inhibitor in development for the treatment of type 2 diabetes that improves glycemic control by enhancing alpha- and beta-cell responsiveness to glucose. Two open-label, single-dose, randomized, crossover studies in healthy subjects (ages 18-45 years) investigated the dose proportionality of vildagliptin pharmacokinetics (n = 20) and the effect of food (n = 24) on vildagliptin pharmacokinetics. There was a linear relationship (r(2) = 0.999) between vildagliptin doses of 25, 50, 100, and 200 mg and area under the plasma concentration-time curve from time zero to infinity (AUC(0-infinity)) and maximum plasma concentration (C(max)). Dose proportionality was assessed using a statistical power model [X = alpha x (dose)(beta)]. The 90% confidence intervals of the proportionality coefficient, beta, for AUC(0-infinity) (1.15-1.19) and C(max) (1.04-1.14) indicated that deviations from dose ...

2007-07-26

38

Home radon levels and seasonal correction factors for the Isle of Man  

Energy Technology Data Exchange (ETDEWEB)

Ionizing radiation dose levels due to home radon can rise to levels that would be illegal for workers in the nuclear industry. It is well known that radon levels within homes and from home to home, and also from month to month, vary considerably. To define an Isle of Man radon seasonal correction factor, readings were taken in eight homes over a 12 month period. An average island indoor exposure of 48 Bq m{sup -3} (range 4-518 Bq m{sup -3}) was determined from 285 homes selected from a cohort of 1300 families participating in the European Longitudinal Study of Pregnancy and Childhood (ELSPAC) in the Isle of Man. This compares with a UK home average of 20 Bq m{sup -3} and a European Union average (excluding UK) of 68 Bq m{sup -3}. Ten homes of those measured were found to have radon levels above the National Radiological Protection Board 200 Bq m{sup -3} action level. There are 29 377 homes on the Isle of Man, suggesting ...

2000-08-01

39

Portal fibrosis in the livers of alcoholic patients.  

UK PubMed Central (United Kingdom)

Liver biopsies in nine of 70 male alcoholics seen during a 12 month period showed predominantly portal fibrosis with fatty change, but little or no alcoholic hepatitis. None of the 30 female alcoholics...Full Text Available

1978-11-01

40

Changes in health utilities and health-related quality of life over 12 months following radical prostatectomy  

UK PubMed Central (United Kingdom)

Introduction:Although radical prostatectomy (RP) is an effective treatment for prostate cancer, it has potentially deleterious effects on health-related quality of life (HRQoL)....Full Text Available

2009-12-01

41

Anemia and growth status in pediatric patients receiving maintenance dialysis after a failed renal transplant course: an NAPRTCS report.  

Science.gov (United States)

We conducted a retrospective review of the North American Renal Transplant Cooperative Study (NAPRTCS) Registry transplant and dialysis arms to assess anemia and growth patterns in children who returned to dialysis after a failed renal transplant from January 1, 1992 to February 3, 2004. Of the 1807 potential study subjects, 1451 had transplant removal data (TxIn vs. TxOut) available for analysis. Four hundred and twenty-one of 1451 patients (29%) had a transplant nephrectomy at the time of entry into the NAPRTCS Registry Dialysis arm. Anemia rates steadily decreased from 72.2% at 30 days after dialysis initiation to 59.5% at 12 months after dialysis initiation. Factors associated with anemia at 30 days after dialysis initiation included hemodialysis, lack of Epo use, and patients who comprised earlier study era cohorts. At one yr after return to dialysis, earlier ...

2007-03-01

42

Inhalation of tobacco smoke induces increased proliferation of urinary bladder epithelium and endothelium in female C57BL/6 mice  

International Nuclear Information System (INIS)

Cigarette smoking is the major environmental risk factor for bladder cancer in humans. Aromatic amines, potent DNA-reactive bladder carcinogens present in cigarette smoke, contribute significantly. However, increased cell proliferation, caused by direct mitogenesis or in response to cytotoxicity, may also play a role since urothelial hyperplasia has been observed in human cigarette smokers. We examined the urothelial effects of cigarette smoke (whole body inhalation exposure (Teague) system) in female C57BL/6 mice at various times in two studies, including reversibility evaluations. In both studies, no urothelial hyperplasia was observed by light microscopy in any group. However, in study 1, the Ki-67 labeling index (LI) of the urothelium was significantly increased in the smoke exposed group compared to controls through 3 months, but was not present at 6, 9 or 12 months even with ...

2007-11-20

43

An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial  

British Library Electronic Table of Contents (United Kingdom)

Summary Background Treatment of localised renal cell carcinoma consists of partial or radical nephrectomy. A substantial proportion of patients are at risk for recurrence because no effective adjuvant therapy exists. We investigated the use of an autologous, tumour-derived heat-shock protein (glycoprotein 96)-peptide complex (HSPPC-96; vitespen) as adjuvant treatment in patients at high risk of recurrence after resection of locally advanced renal cell carcinoma. Methods In this open-label trial, patients were randomly assigned to receive either vitespen (n=409) or observation alone (n=409) after nephrectomy. Randomisation was done in a one to one ratio by a computer-generated pseudo-random number generator, with a block size of four, and was stratified by performance score, lymph node stat...

2008-01-01

44

Prevention of panic attacks and panic disorder in COPD.  

Science.gov (United States)

This study examined whether cognitive behavioural therapy (CBT) could prevent the development or worsening of panic-spectrum psychopathology and anxiety symptoms in chronic obstructive pulmonary disease (COPD). 41 patients with COPD, who had undergone pulmonary rehabilitation, were randomised to either a four-session CBT intervention condition (n = 21) or a routine care condition (n = 20). Assessments were at baseline, post-intervention, and at 6-, 12- and 18-month follow-ups. Primary outcomes were the rates of panic attacks, panic disorder and anxiety symptoms. Secondary outcomes were depressive symptoms, catastrophic cognitions about breathing difficulties, disease-specific quality of life and hospital admission rates. There were no significant differences between the groups on outcome measures at baseline. By the 18-month follow-up assessment, 12 (60%) routine care group participants had experienced at least one panic attack in the previous 6 months, with two ...

2009-09-09

45

Host resistance to rat cytomegalovirus (RCMV) and immune function in adult PVG rats fed herring from the contaminated Baltic Sea  

Energy Technology Data Exchange (ETDEWEB)

We carried out a feeding study in rats aimed at extending our aboservations of contaminant-induced immunosuppression in harbour seals. Two herring batches were freeze-dried, supplemented and fed to female adult PVG rats for a period of 4 1/2 months. Daily contaminant intakes of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxic equivalents (TEQ) were estimated to be 0.3 ng/kg body weight and 1.6 ng/kg in the Atlantic and Baltic groups, respectively. At the end of the feeding experiment, no contaminant-related changes in spleen CD{sub 4}{sup +}/CD{sub 8}{sup +} cellularity, natural killer cell activity, or mitogen-induced proliferative responses of thymus or spleen cells could be detected. However, total thymocyte numbers and thymus CD{sub 4}{sup +}/CD{sub 8}{sup +} ratios were reduced in the Baltic group. A novel model was established to assess the specific T-cell response to rat cytomegalovirus (RCMV). When applied to the feeding study, no ...

1996-08-01

46

For early diagnosis of the fracture healing, nonunion and avascular necorsis  

Energy Technology Data Exchange (ETDEWEB)

Complications of non-union and avascular necrosis during fracture healing process are the most important problems. Early detection of the evidence of non-union and avascular necrosis and follow-up study of fracture healing process will reduce complications and sequellae in fracture patients. Femoral neck and tibial shaft are the most important fracture sites where non-union and/or avascular necorsis are frequently developed. Osteomedullography was performed in 30 cases of fracture, 21 femoral neck, 8 tibial shafts and 1 talar neck, in the Department of Radiology of national Medical Center during the period form August 1977 to March 1981. The following results were obtained: 1. 16 patients of femoral neck fracture were performed osteomedullography one. Non-union showing no crossing vein through the fracture site was noted in 12 cases from 16 patients. 4 cases from the 12 patients of non-union showed decreased viability but 2 case revealed good viability of the ...

1981-09-15

47

The Two-Column Aerosol Project (TCAP) Science Plan  

Energy Technology Data Exchange (ETDEWEB)

The Two-Column Aerosol Project (TCAP) field campaign will provide a detailed set of observations with which to (1) perform radiative and cloud condensation nuclei (CCN) closure studies, (2) evaluate a new retrieval algorithm for aerosol optical depth (AOD) in the presence of clouds using passive remote sensing, (3) extend a previously developed technique to investigate aerosol indirect effects, and (4) evaluate the performance of a detailed regional-scale model and a more parameterized global-scale model in simulating particle activation and AOD associated with the aging of anthropogenic aerosols. To meet these science objectives, the Atmospheric Radiation Measurement (ARM) Climate Research Facility will deploy the ARM Mobile Facility (AMF) and the Mobile Aerosol Observing System (MAOS) on Cape Cod, Massachusetts, for a 12-month period starting in the summer of 2012 in order to quantify aerosol properties, radiation, and ...

2011-07-27

48

Stereotactic iridium-192 interstitial brachytherapy for intracranial malignant tumors; Combined with hyperthermia  

Energy Technology Data Exchange (ETDEWEB)

The results of interstitial brachytherapy in 13 patients with malignant brain tumors (malignant glioma 9 cases, metastatic brain tumor 4 cases) were reported. In all patients, Ir-192 thin wires were implanted temporarily in afterloading catheters, which were implanted appropriately by means of MRI or CT guided stereotactic technique. Clinical results on CT scan were as follows: CR (complete response) 1 case, PR (partial response) 6 cases and NC (no change) 6 cases. Even in the NC group, tumor growth was inhibited temporarily. Tumor free intervals were ranged 2-17 months. In early series, the intervals were about 2 months due to incomplete arrangement of radioactive implants. In recent series, prolongation of tumor free interval more than 12 months was achieved due to precise arrangements of implants. MRI guided stereotactic interstitial brachytherapy may provide safe and precise intracranial arrangements of implants, which yield high radiation ...

1990-05-01

49

Stereotactic iridium-192 interstitial brachytherapy for intracranial malignant tumors  

International Nuclear Information System (INIS)

The results of interstitial brachytherapy in 13 patients with malignant brain tumors (malignant glioma 9 cases, metastatic brain tumor 4 cases) were reported. In all patients, Ir-192 thin wires were implanted temporarily in afterloading catheters, which were implanted appropriately by means of MRI or CT guided stereotactic technique. Clinical results on CT scan were as follows: CR (complete response) 1 case, PR (partial response) 6 cases and NC (no change) 6 cases. Even in the NC group, tumor growth was inhibited temporarily. Tumor free intervals were ranged 2-17 months. In early series, the intervals were about 2 months due to incomplete arrangement of radioactive implants. In recent series, prolongation of tumor free interval more than 12 months was achieved due to precise arrangements of implants. MRI guided stereotactic interstitial brachytherapy may provide safe and precise intracranial arrangements of implants, which yield high radiation ...

1990-01-01

50

Early detection by sup(99m)Tc-Sn-pyrophosphate scintigraphy of femoral head necrosis following medial femoral neck fractures  

International Nuclear Information System (INIS)

A selected series of 24 patients with displaced medial femoral neck fracture, treated with closed reduction and osteosynthesis with cancellous bone screws (ASIF), were investigated. During an observation period of 6 to 26 months, serial hip joint scintigraphies were performed and compared with serial X-ray examinations. At the first scintigraphic examination performed on average 5-6 weeks after the fracture, two separate investigators found a decreased amount of activity or no activity in the femoral head of 10 and 8 patients, respectively. At the second scintigraphic examination performed on average 11.1 weeks after the fracture both investigators found no activity or a decreased amount of activity in 8 patients. This figure declined to 7 during the following period, because one patient with decreased activity was recorded as having normal activity 15 months after the fracture. These 7 patients all developed radiological signs of femoral head collapse on average 16.3 months after the ...

51

Comparison of stereotactic radiosurgery and fractionated stereotactic radiotherapy of acoustic neurinomas according to 3-D tumor volume shrinkage and quality of life  

International Nuclear Information System (INIS)

Background and purpose: stereotactic radiosurgery (SRS) and also fractionated stereotactic radiotherapy (SRT) offer high local control (LC) rates (> 90%). This study aimed to evaluate three-dimensional (3-D) tumor volume (TV) shrinkage and to assess quality of life (QoL) after SRS/SRT. Patients and methods: from 1999 to 2005, 35/74 patients were treated with SRS, and 39/74 with SRT. Median age was 60 years. Treatment was delivered by a linear accelerator. Median single dose was 13 Gy (SRS) or 54 Gy (SRT). Patients were followed up ? 12 months after SRS/SRT. LC and toxicity were evaluated by clinical examinations and magnetic resonance imaging. 3-D TV shrinkage was evaluated with the planning system. QoL was assessed using the questionnaire Short Form-36. Results: Median follow-up was 50/36 months (SRS/SRT). Actuarial 5-year freedom from progression/overall survival was 88.1%/100% (SRS), and 87.5%/87.2% (SRT). TV ...

2009-09-01

52

A randomised controlled trial of intervention site radiotherapy in malignant pleural mesothelioma  

International Nuclear Information System (INIS)

Background and purpose: To assess the effectiveness of radiotherapy in preventing tumour seeding after chest drain or pleural biopsy in patients with malignant mesothelioma and to determine, if tract metastases appear, whether they are tender or troublesome to patients. Patients and methods: Patients with a histological diagnosis of pleural mesothelioma and an invasive procedure within the preceding 21 days were stratified by age, performance status and treatment centre. Randomisation was performed between immediate drain site radiotherapy 21 Gy in three fractions (XRT arm) or best supportive care (BSC) with follow-up to 12 months. Patients were asked to complete questionnaires on treatment toxicity and on symptoms from any tract metastases detected. Results: Sixty-one patients were recruited from two centres between 1998 and 2004; 56 men, 5 women, median age 70. 31 were allocated to drain site radiotherapy. Seven patients developed tract ...

2007-07-01

53

Significance of cranial computer tomography for the early diagnosis of peri- and postnatal damage  

Energy Technology Data Exchange (ETDEWEB)

It is reported on examination-technical possibilities with craniocerebral Computer Tomography in the peri- and postnatal period. Some typical tomographic images from a 17 1/2 months period in our own patient material of 327 children are demonstrated. The special advantages of this new technical-extensive method are: exact diagnoses, observation possibility of the longitudinal section, and the absolute harmlessness to the child.

1981-01-01

54

Excessive copper concentrations in the tap water of households with copper pipes and an assessment of possible health hazards for infants. First results of a study; Gesundheitliche Gefaehrdung ungestillter Saeuglinge durch Kupfer in Haushalten mit kupfernen Trinkwasserleitungen. Erste Ergebnisse einer prospektiven Studie  

Energy Technology Data Exchange (ETDEWEB)

To determined precisely a possible connection between the amount of copper in tap-water and the risk of early childhood liver disease, it was attempted through an epidemiological survey, to determine the extent of excessive concentrations of copper in the tap-water of households with copper pipes. Water samples from 956 households were tested for copper, and the state of health of the infants in these households was documented. Infants who had been fed using water with a copper concentration of 0.8 mg/l or more received a paediatric examination with a blood serum analysis to rule out any liver damage. A copper level greater than 0.8 mg/l was found in only 2% of the households examined. Eight infants were examined by a paediatrician and their serum was analysed. These infants had either been breast-fed to the 12th week or had received more than 200 ml of tap water per day during first 12 months. None of the infants examined showed any signs of ...

2000-04-01

55

Radiation processing as a post-harvest quarantine control for raisins, dried figs and dried apricots  

International Nuclear Information System (INIS)

The commercially packed samples of raisins, dried figs and dried apricots were irradiated using doses in the range of 0.5-1.0 kGy for disinfestation and 0.5-5.0 kGy for sensory analysis with the dose rate ranging from 1.44 to 1.92 kGy/h. Pests on dried fruits were evaluated after 0, 1, 2 and 3 months of storage for irradiated dried figs and 1, 3, 6 and 12 months of storage for raisins and dried apricots. Sensory analysis of dried figs, dried apricots and raisins were carried out after 0, 1, 3, 6 and 12 months of storage. The results indicated that radiation processing at low doses (#approx#1.0 kGy) is an effective post-harvest treatment and quarantine control for these products with no adverse effects on sensory (marketing) attributes.

2006-03-01

56

Effects of gamma irradiation on the physical properties of laminated packaging materials. 2. polypropylene-polypropylene, polypropylene-polyethylene, and polyester-polyethylene  

International Nuclear Information System (INIS)

This experiment was done to determine the effects of irradiation on the physical properties of three kinds of laminated packaging materials, i.e. polypropylene-polypropylene, polypropylene-polyethylene, polyester-polyethylene. Observations were made on pinhole production, leakage, oil resistance, resistance against insect penetration, colour, odour tensile strength, elongation at break, seal strength and tear resistance. The samples were irradiated with doses of 0, 5 and 10 kGy, then stored at room temperature and examined after 0, 3, 6 and 12 months of storage. The results showed that irradiation doses up to 10 kGy, as well as storage up to 12 months, did not create pinholes, or leakage in pouches prepared from laminated films. The resistance of the films to oil and insect penetration, the colour, and the odour were also unchanged. Both irradiation and storage treatments had a significant effect on ...

57

“Bridge population”: sex workers or their clients? - STI prevalence and risk behaviors of clients of female sex workers in China  

British Library Electronic Table of Contents (United Kingdom)

As the HIV/AIDS epidemic and the spread of sexually transmitted infections (STIs) in China has come to the forefront of public health attention, female sex workers (FSWs) and their clients (CFSWs) are becoming increasingly important to HIV/STI prevention efforts. This secondary analysis uses data abstracted from the Chinese Health and Family Life Survey 1999-2000 to report prevalence rates of two STIs as well as sexual risk behaviors for CFSWs - men who paid for sex with FSWs in the past 12 months - in comparison with men who had not patronized FSWs. Among 1879 Chinese CFSWs who completed anonymous interviews and urine testing, 152 (6.3%, weighted) said they had paid for sex in the past 12 months and 18.8% of CFSWs (weighted) tested positive for gonorrhea. CFSWs were 10 times more likely t...

2011-01-01

58

Refocusing Forties operations engineering  

Energy Technology Data Exchange (ETDEWEB)

Faced with a changing business emphasis, plus the need to reduce operations and maintenance costs in the North Sea, the Forties Field engineering partnership between BP and Brown and Root recognised the need to make radical changes in its organisational structure. An innovative change management programme was planned and executed inside 12 months with the purpose of right-sizing the Forties Operations Engineering team. Not only has the initiative succeeded in cutting costs by 40 per cent; it has also enhanced the quality of engineering support services supplied to the BP Forties platforms. (author)

1996-12-31

59

Avascular necrosis associated with nailing of femoral neck fracture  

Energy Technology Data Exchange (ETDEWEB)

Two patients with femoral neck fractures, one displaced and one undisplaced, are presented. Preoperative intravital staining with tetracycline and Tc-MDP scintimetry both showed intact femoral head circulation while Tc-MDP-scintimetry 1 week after operation showed pronounced circulatory deficiency. Sr/sup 85/-scintimetry performed at the same time was inconclusive. Segmental collapse was observed radiographically, 8 and 12 months postoperatively. The major vascular injury resulting in avascularity most probably occured during the procedure of osteosynthesis, and Tc-MDP-scintimetry was found suitable for early postoperative recognition of avascular necrosis in both fractures.

1983-01-01

60

Avascular necrosis associated with nailing of femoral neck fracture  

International Nuclear Information System (INIS)

Two patients with femoral neck fractures, one displaced and one undisplaced, are presented. Preoperative intravital staining with tetracycline and Tc-MDP scintimetry both showed intact femoral head circulation while Tc-MDP-scintimetry 1 week after operation showed pronounced circulatory deficiency. SR"8"5-scintimetry performed at the same time was inconclusive. Segmental collapse was observed radiographically, 8 and 12 months postoperatively. The major vascular injury resulting in avascularity most probably occured during the procedure of osteosynthesis, and Tc-MDP-scintimetry was found suitable for early postoperative recognition of avascular necrosis in both fractures. (author).

61

Percutaneous intervention in the menagement of insufficient native arteriovenous hemodialysis fistulae  

Energy Technology Data Exchange (ETDEWEB)

To determine the effectiveness and patency of percutaneous intervention in insufficient native arteriovenous hemodialysis fistulae (AVFs). Between March 1997 and September 2001, 67 cases of insufficient native AVFs resulted from central vein lesion, PTA was performed in 48 cases, and thrombolytic therapy with or without PTA in 11. In eight of the cases, in which central vein stenosis had led to the insufficency, percutaneous transluminal angioplasty (PTA) was performed, and in three of the eight, a stent was inserted. Angiography findings and complications, as well as success and patency rates in the non-thrombosis and thrombosis group, were evaluated; the central vein lesion group was analysed separately. Among 84 lesions observed at angiography, three were 54 cases of stenosis, 17 of occlusion, and 13 of combined thrombosis. The lesions were located in a proximal vein (n=51), distal vein (n=14), artery (n=6), and at the site of anastomosis (n=13). In the central vein lesion group ...

2002-11-01

62

Penile injury and effect on male sexual function  

British Library Electronic Table of Contents (United Kingdom)

Summary Penile injury is common as an emergency and should be accurately diagnosed and treated. We analysed 22 patients with penile injury admitted to the emergency unit of Dubrava University Hospital during a 4-year period. According to the American Association for the Surgery of Trauma five-grade classification of penile injuries, there were 14 grade I, 6 grade II and 2 grade III cases. Diagnosis was mainly based on clinical and ultrasonography findings, and in some cases on cavernosography. Nineteen patients underwent immediate surgery and three patients received conservative therapy. On outpatient follow up, sexual function was assessed by use of the 5-item International Index of Erectile Function (IIEF-5) test at 3 and 12-months of injury. At 3-month follow up, moderate, mild and no e...

2011-01-01

63

Orthognathic treatment with maxillary and mandibular anterior segmental osteotomy  

British Library Electronic Table of Contents (United Kingdom)

This case report presents a case that underwent orthognathic treatment with anterior segmental osteotomies on both jaws. The patient was a 26-year-old female with maxillary protrusion, lip incompetence with an everted vermilion border. The overbite was +1.0mm, overjet +1.0mm. The pre-surgical orthodontic treatment included the extraction of the four first premolars and a multi-bracket treatment was started. After 12 months of pre-surgical orthodontic treatment, both the anterior maxillary and the anterior mandibular segments were retracted surgically by 5.5mm. The total treatment period was 18 months. An anterior segmental osteotomy can induce the remarkable structural changes for bimaxillary lip protrusion patients.

2009-01-01

64

Orthognathic treatment case after severe root resorption in the early treatment stage  

British Library Electronic Table of Contents (United Kingdom)

This article presents an orthognathic treatment case after severe apical root resorption of maxillary anterior teeth using anterior segmental osteotomy. This case involved a 20-year-old female with the chief complaint of maxillary protruding and irregularly aligned mandibular anterior teeth. Her medical history showed no allergies or medical problems. The overbite was +3.0mm, and the overjet +3.0mm. After extraction of the four first premolars, a multi-bracket treatment was started. A severe root resorption of the maxillary anterior teeth was found 12 months after active treatment. The maxillary anterior segmental osteotomy was chosen as the compensatory treatment. The total treatment period was 2 years and 7 months. The post-retention panoramic radiograph showed no developmental root reso...

2009-01-01

65

Clinical issues in considering vagus nerve stimulation for treatment-resistant depression  

British Library Electronic Table of Contents (United Kingdom)

This review briefly discusses the clinical and basic science rationale for vagus nerve stimulation (VNS) in treatment-resistant depression (TRD). As the number of treatment failures for depression increases, the likelihood of achieving remission during acute treatment decreases, and the risk of relapse increases with the number of treatment failures. Two open trials of adjunctive VNS for TRD showed positive acute results and a growing benefit over time. The results of the acute randomized controlled trial were not significant for the primary outcome (response by HRSD-24), but the secondary measure (IDS-SR-30) was significant for VNS. A 12-month nonrandomized comparative analysis of patients receiving adjunctive VNS with TRD patients receiving treatment as usual showed significant results f...

2009-01-01

66

Phase 2 Final Report. IAEA Safeguards: Implementation blueprint of commercial satellite imagery  

International Nuclear Information System (INIS)

This document - IAEA Safeguards: Implementation Blueprint of Commercial Satellite Imagery - constitutes the second report from SSC Satellitbild giving a structured view and solid guidelines on how to proceed with a conceivable implementation of satellite imagery to support Safeguards activities of the Agency. This Phase 2 report presents a large number of concrete recommendations regarding suggested management issues, work organisation, imagery purchasing and team building. The study has also resulted in several lists of actions and preliminary project plans with GANT schedules concerning training, hardware and software, as well as for the initial pilot studies. In both the Phase 1 and Phase 2 studies it is confirmed that the proposed concept of a relatively small Imagery Unit using high-resolution data will be a sound and feasible undertaking. Such a unit capable of performing advanced image processing as a tool for ...

1989-08-01

67

Percutaneous transluminal angioplasty and thrombolysis in the management of insufficient hemodialysis access: Long-term patency rates and factors affecting patency rates  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the success rates, long-term patency rates and factors affecting the patency rates of percutaneous transluminal angioplasty(PTA) and thrombolysis in the management of insufficient access during hemodialysis. Between January 1991 and March 1995, 37 insufficient shunts(23 native fistulae and 14 graft fistulae) were treated in 31 patients. PTA was performed in 24 shunts, and thrombolysis in 13;in seven of these latter, thrombolysois was followed by PTA. The success and long-term patency rates of PTA and thrombolysis were evaluated. Shunts were subdivided according to a patient's age, type and age of the shunt, and number and length of the stenosis, and the degree of residual stenosis and in each subgroup, patency rates was compared. The overall success rate of PTA and thrombolysis for insufficient hemodialytic access was 78.4%(29/37). The success rates of PTA and thrombolysis were 91.7%(22/24) and 53.8%(7/13), respectively. The patency rates of PTA (85.7% at 6 months, ...

1997-10-01

68

Percutaneous transluminal angioplasty and stent insertion in central venous steno-occlusion  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the efficacy of percutaneous transluminal angioplasty (PTA) and stent insertion in central venous steno-occlusion. Between August 1992 and January 1998, 11 patients with symptomatic central venous steno-occlusion (six stenoses and five occlusions) underwent pereutaneous treatment. Eleven PTAs were performed and stents were introduced in two patients because of incomplete PTA. During follow-up, a total of eight revisions were performed in five patients with recurrence (six stenoses and two occlusions). Success and long term patency rates were evaluated. The length and degree of the lesion and degree of residual stenosis, as well as pressure gradient through the lesion and decrease of the gradient after PTA, were correlated with patency rates. Complications during the procedures and follow-up period were evaluated. The overall success rate was 89.5%;those of primary and revision intervention were 90. 9% and 87.5%, respectively. Primary and revision patency rates were 72.7% ...

1998-12-01

69

Visual recovery after vitrectomy for macular hole using 25-gauge instruments  

British Library Electronic Table of Contents (United Kingdom)

Abstract. Purpose: To determine whether vitrectomy with 25-gauge instruments contributes to better postoperative visual recovery after macular hole (MH) surgery. Methods: The medical records for 46 consecutive eyes operated for MH by a single surgeon were retrospectively examined. Vitrectomy had been performed with a 25-gauge instrument in 23 eyes (25-G group) and with a 20-gauge instrument in 23 eyes (20-G group). Postoperative visual acuity (VA) in logMAR (logarithm of the minimum angle of resolution) units after 1 week and 1, 3, 6, 9 and 12 months, operating time, and volume of intraocular irrigating fluid were compared between the two groups. Results: Mean preoperative logMAR VA was 0.72 in the 25-G group and 0.68 in the 20-G group (p = 0.282, unpaired t-test). One week after surgery, ...

2008-01-01

70

Treatment of proliferative haemangiomas with the 585 nm pulsed dye laser.  

Science.gov (United States)

Haemangiomas usually develop within the first few weeks of life, most regressing spontaneously before the age of 7 years. Some may ulcerate or compromise a vital function, in which case systemic corticosteroids, surgery or radiotherapy may be helpful. All of these treatment modalities are associated with significant morbidity. Treatment with the 585 nm flashlamp pulsed dye laser is safe and effective in the management of superficial vascular malformations. We report seven patients, under 12 months of age, who presented with proliferative haemangiomas, causing functional impairment. Ulcerated lesions were present in four patients. The patients were treated with the 585 nm pulsed dye laser (fluences 7.0-9.25 J/cm2), at intervals of 4-8 weeks. All of the lesions showed a significant reduction in size, together with improvement in the colour and integrity of the overlying skin. Treatment with the 585 nm pulsed dye laser should be considered in the ...

1996-04-01

71

Solar expriment begins at Atlanta school. [George A. Towns Elementary School  

Science.gov (United States)

The largest solar heating and cooling system undertaken to date is now operating at the George A. Towns Elementary School in Atlanta, Georgia. It is expected to provide more than 60 percent of the building's heating and cooling requirements, using commercially available components and techniques. The Towns project is a United States Energy Research and Development Administration-sponsored experiment. The principal components of the solar heating and cooling system designed for the school--the solar collector array, the existing gas-fired boiler, the absorption chiller, and hot and cold water underground tanks to provide thermal storage--are described. To derive maximum benefit from the experiment, the system is fully instrumented for accurate measurement of performance. Environmental data, including insolation and ambient temperture, humidity, and wind conditions will be recorded. The inlet temperatures, outlet temperatures, and the mass flow rates to the collectors, storage ...

1976-03-01

72

Radial keratoneuritis as a presenting sign in acanthamoeba keratitis.  

Science.gov (United States)

The visual outcomes of Acanthamoeba keratitis, a rare cause of corneal infection, can be devastating. This paper reports two contact lens wearers with severe pain and photophobia who presented to the emergency room. Biomicroscopy revealed radial keratoneuritis in both individuals. Tissue culture on a nonnutrient agar plate with Escherichia coli overlay resulted in a heavy growth of Acanthamoeba. The inpatient treatment included 0.02% polyhexamethylene biguanide, chlorhexidine, neomycin/polymyxin B/bacitracin (Neosporin), and oral fluconazole, which successfully controlled the corneal infection and improvement in the best corrected visual acuity in both patients. Infection did not recur during the 12-month follow-up period. Acanthamoeba keratitis can present as radial keratoneuritis, mimicking other common corneal infections resulting in diagnostic and treatment delays. Early diagnosis and prudent treatment of Acanthamoeba keratitis are the keys ...

2011-07-01

73

Irradiation of spices, packaging materials and luncheon to improve the storability of the end product  

International Nuclear Information System (INIS)

Spices and packaging materials were exposed to gamma irradiation at a dose of 10 KGy. Luncheon was prepared with irradiated or non-irradiated spices. Prepared luncheon was packaged in irradiated or non-irradiated packaging materials. Packaged luncheon was treated with 2 KGy. Treated and untreated packaged luncheon were kept in a refrigerator (1-4 Centigrade) for 12 months. Microbiological, nutritive and chemical characteristics of luncheon were evaluated after processing and during storage; whereas, sensory quality was evaluated only after irradiation. Gamma irradiation decreased the microorganisms counts of spices, packaging materials and packed luncheon and increased the shelf-life of packaged luncheon products. No major differences in moisture, protein, fat, ph value, total acidity, lipid peroxide and volatile basic nitrogen were observed due to irradiation. Sensory evaluation showed that all the combination treated luncheon were acceptable ...

74

Estimation of seasonal correction factors through Fourier decomposition analysis-a new model for indoor radon levels in Irish homes  

Energy Technology Data Exchange (ETDEWEB)

Radon concentrations in homes have been shown to vary considerably with season. It is important to account for this by applying a correction factor to any home radon measurement of less than one year. To date, Irish radon measurement services have used correction factors based on data derived for the UK in the 1980s. In the absence of similar data for Ireland at the time, these were considered suitable for use due to the similarities between the climates, house types and lifestyles in the two countries. In order to better estimate the long-term radon concentration, measurements from 5640 Irish homes were used to derive a set of correction factors specifically for Ireland. These were generated by means of Fourier decomposition analysis and the new correction factors compared, using 95% confidence intervals, to those derived for the UK using the same analysis and to those currently in use for Ireland. In both cases, a significant difference was found between 10 of the ...

2010-09-15

75

Effect of percutaneous transluminal angioplasty in insufficiency of arteriovenous fistula for hemodialysis  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the effectiveness of percutaneous transluminal angioplasty(PTA) and to determine the factors affecting the long-term patency rate in the management of insufficient hemodialytic arteriovenous fistula(AVF). Forty-nine cases of insufficient hemodialytic AVF were treated in 44 patients(native AVF:20, graft AVF:29, M:17, F:27, Age:22-70 years). In 28 thrombus patients, thrombolysis was performed with urokinase, and was followed by PTA. The initial success rate and complications of PTA were evaluated. According to the site and length of the stenosis, type and age of the AVF, the presence or abscence of thrombus, a history of diabetic mellitus, the patient's age, and the duration of renal failure, patency rates were compared within each subgroup using the Kaplan-Meier logrank test. The initial success rate of PTA for insufficient hemodialytic AVF was 88%(43/49), the patency rate of PTA was 67% at 6 months, and 50% at 12 months. ...

1999-06-01

76

Corrosion of container materials for disposal of high-level radioactive wastes  

Energy Technology Data Exchange (ETDEWEB)

In the corrosion aspect of container for the deep geological disposal of high-level radioactive waste, disposal concepts and the related container materials, which have been developed by advanced countries, have been reviewed. The disposal circumstances could be divided into the saturated and the unsaturated zones. The candidate materials in the countries, which consider the disposal in the unsaturated zone, are the corrosion resistant materials such as supper alloys and stainless steels, but those in the saturated zone is cupper, one of the corrosion allowable materials. By the results of the pitting corrosion test of sensitized stainless steels (such as 304, 304L, 316 and 316L), pitting potential is decreased with the degree of sensitization and the pitting corrosion resistance of 316L is higher than others. And so, the long-term corrosion experiment with 316L stainless steel specimens, sebsitized and non-sensitized, under the compacted bentonite and synthetic granitic groundwater ...

1999-01-01

77

Comparative investigation of corrosion resistance of steel reinforcement in alinite and Portland cement mortars  

Energy Technology Data Exchange (ETDEWEB)

The corrosion resistance of steel-reinforced mortar specimens made from alinite cement was investigated using ordinary Portland cement (OPC) specimens as reference. The specimens were prepared and exposed in three different environments: continuous exposure in tap water, interrupted exposure in tap water, and interrupted exposure in 3.5% NaCl solution. The steel weight loss and the half cell potential were measured vs. exposure time, up to the age of 12 months. Pore solution extraction and analysis and porosity determination were also performed. In continuous exposure in tap water, alinite cement provided adequate protection against corrosion. In interrupted exposure in tap water, a higher corrosion was observed for alinite cement compared to OPC. In the case of interrupted exposure in 3.5% NaCl solution, the simultaneous action of free chlorides and oxygen resulted in the depassivation of steel reinforcing bars in alinite and Portland cement ...

1998-07-01

78

Animal models of ionizing-radiation damage. Technical report, 18 May 88-18 May 91  

Energy Technology Data Exchange (ETDEWEB)

This report is a survey of the English language literature of radiation biology between 1947 and 1987, for the purpose of compiling a literature base on the effects of radiation on animals, which have yielded results that can expand our knowledge about similar radiation effects on human beings. Articles were sought that reported exposure of adult mammals to external sources of ionizing radiation, having endpoints that included effects on the brain, the spinal cord, and behavior of the gastrointestinal, endocrine, and cardiovascular systems and the hematopoietic and immune systems. Effects of interest were those that occurred within the first 12 months after exposure. The survey does not include articles reporting chronic or long term delayed effects of radiation unless they provided insight into mechanisms of morphological and/or functional derangement. Information presented in the report is divided into subtopics (i.e., Brain-Morphological ...

1992-01-01

79

[Peritonitis in the course of peritoneal dialisis caused by Haemophilus influenzae with BLNAR phenotype].  

Science.gov (United States)

Most common bacterial species causing peritonitis in the course of peritoneal dialysis (PDP) are coagulase-negative staphylococci, Staphylococcus aureus and streptococci. Haemophilus influenzae is rarely associated with PDP. Hereby we present the first known case of APD-associated peritonitis caused by non-type able H. influenzae (NTHi) presenting the beta-lactamase negative, ampicillin-resistant (BLNAR) phenotype. An 18 year old boy who had been treated with the APD for 12 months due to SLE was admitted in good general condition with diagnosis of PDP. Standard diagnostic and therapeutical procedures were initiated. Dialysis fluid was turbid with cytosis of 435 WBC/ml. From dialysis fluid pure culture of Gram-negative coccobacillus was isolated. The isolate was identified as a BLNAR phenotype. The same bacterium was isolated from nasal swab. Blood cultures were negative. After evaluation of antimicrobial susceptibility the treatment was changed ...

2009-04-01

80

Total skin electron beam therapy for cutaneous lymphomas and leukemias  

International Nuclear Information System (INIS)

Total skin electron beam therapy (TSEB) was used in the treatment of 33 patients with lymphoma and 13 patients with leukemia involving extensive segments of the skin surface. Twenty-two of 23 had lesions as a primary manifestation of lymphoma (primary cutaneous lymphoma-PCL) and 11 developed cutaneous lesions following disseminated nodal lymphoma (secondary cutaneous lymphoma-SCL). A once weekly fractionation scheme was employed to irradiate the entire skin surface with 3.5 to 4 MeV electron beam from a 6 MeV linear accelerator. During each weekly session, 400 rad were delivered to the entire skin and a complete course consisted of 4-6 consecutive weekly sessions. The majority of patients have been previously treated elsewhere for various periods and all patients have been at risk for a median of 12 months, range from 12-117 months following TSEB. Striking predominance of the diffuse pattern (76%) was demonstrated in both the PCL and SCL. There ...

81

The Primary Patency and Fracture Rates of Self-Expandable Nitinol Stents Placed in the Popliteal Arteries, Especially in the P2 and P3 Segments, in Korean Patients  

Energy Technology Data Exchange (ETDEWEB)

We wanted to evaluate the status of self-expandable nitinol stents implanted in the P2 and P3 segments of the popliteal artery in Korean patients. We retrospectively analyzed 189 consecutive patients who underwent endovascular treatment for steno occlusive lesions in the femoropopliteal artery from July 2003 to March 2009, and 18 patients who underwent stent placement in popliteal arterial P2 and P3 segments were finally enrolled. Lesion patency was evaluated by ultrasound or CT angiography, and stent fracture was assessed by plain X-rays at 1, 3, 6 and 12 months and annually thereafter. At the 1-month follow-up, stent fracture (Type 2) was seen in one limb (up to P3, 1 of 18, 6%) and it was identified in seven limbs at the 3-month follow-up (Type 2, Type 3, Type 4) (n = 1: up to P2: n = 6: P3). At the 6-month follow-up, one more fracture (Type 1) (up to P3) was noted. At the 1-year follow-up, there were no additional stent fractures. Just four ...

2011-04-15

82

Percutaneous treatment of thrombosed native arteriovenous dialysis fistula insufficiency: efficacy of mechanical thrombectomy with using the stone basket  

Energy Technology Data Exchange (ETDEWEB)

We wanted to evaluate the procedural success after percutaneous treatment of thrombosed native arteriovenous dialysis fistula insufficiency and the efficacy of performing mechanical thrombectomy with using the stone basket. From March 2004 to June 2005, 36 thrombosed native hemodialysis access shunts in the upper limbs (brachiocephalic fistulas: 16 and radiocephalic fistulas: 20) were percutaneously treated in 30 patients. Declotting procedures were performed with using urokinase (100,00-200,000 unit) and manual catheter-directed thrombo-aspiration in all the patients. Angioplasty (6 mm in diameter and 4 cm in length) was performed at the identified area of the stenosis and /or with maceration of the thrombus. In 14 cases with massive thrombosis that was refractory to the above mentioned declotting procedures, mechanical thrombectomy with using a Wittich nitinol stone basket (Cook, Bloomington, IN) was performed. Data regarding the procedural success rate and the patency rate were ...

2006-06-15

83

Outcome of moderately dosed radiosurgery for limited brain metastases. Report of a single-center experience  

International Nuclear Information System (INIS)

Purpose: Efficacy and safety of the own single-center experience with moderately dosed radiosurgery (SRS) for limited (one to four) brain metastases were analyzed and correlated with patient- and treatment-related variables. Patients and Methods: Between 05/1998 and 10/2006, 93 patients received SRS for a total of 142 brain metastases. The median number of brain metastases treated per patient was one (range, one to four). 46 patients (49%) received initial SRS alone, 13 patients (14%) SRS with up-front whole-brain radiotherapy (WBRT), and 34 patients (37%) SRS for recurrent metastases after WBRT. Median dose was 16 Gy (range, 10-20 Gy). Results: Median overall survival (OS) was 7.5 months. The actuarial 6- and 12-month data for OS were 60% and 35%, for local brain control (LBC) 87% and 79%, and for distant brain control (DBC) 48% and 37%, respectively. Only ten of 46 patients (22%) with initial SRS alone ultimately received WBRT. Ten patients ...

2010-02-01

84

Long-Term Follow-Up of Percutaneous Balloon Angioplasty in Adult Aortic Coarctation  

International Nuclear Information System (INIS)

Purpose: To assess long-term outcomes following percutaneous transluminal angioplasty (PTA) of congenital aortic coarctation in adults.Methods: Seventeen patients underwent PTA for symptomatic adult coarctation of the aorta. Sixteen patients, with a mean age of 28 years (range 15-60 years), were reviewed at a mean interval after angioplasty of 7.3 years (range 1.5-11 years). Assessment included magnetic resonance imaging (MRI), Doppler echocardiography, and clinical examination. Current clinical measurements were compared with pre- and immediate post-angioplasty measurements.Results: At follow-up 16 patients were alive and well. The patient not included in follow-up had undergone surgical repair and excision of the coarctation segment following PTA. Mean brachial systolic blood pressure for the group decreased from 174 mmHg before angioplasty to 130 mmHg at follow-up (p 0.0001). The mean gradient had fallen significantly from 50.9 to 17.8 at follow-up (p = 0.001). The average number of ...

2000-09-01

85

Initial and mid-term results of a 4F compatible self-expanding low strut profile nitinol stent in the superficial femoral artery  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To evaluate the initial and mid-term results of a new self-expanding low strut profile nitinol stent for treatment of atherosclerotic lesions stenoses and occlusions in the superficial femoral artery (SFA). Materials and Methods: In 8 patients (4 male, 4 female, mean age 74.8 {+-} 8.8 years) with SFA lesions and non-satisfying results after PTA treatment alone, 10 self-expanding nitinol Xpert stents were deployed via a 4 F sheath. Stent characteristics and handling were graded by the interventionalist. Fontaine classification, duplex flow measurements and ankle brachial index (ABI) at rest and stress were taken prior and one day after stent placement. Patients were followed 3, 6 and 12 months after the procedure obtaining the same parameters at each appointment. Results: Initial stent treatment was successful in all patients. Stent handling and positioning were rated very good and safe. All patients improved clinically by at least one ...

2007-07-15

86

Effective didactic skills training for teachers in continuing medical education  

International Nuclear Information System (INIS)

Purpose: To develop, test, evaluate and implement effective state-of-the-art teacher training in didactic skills and methods. The training concept should be designed and beneficial for medical teachers' postgraduate medical education (CME). Materials and methods: A 5-day workshop with 12 theoretical and 9 'hands-on' modules was designed and stepwise improved, according to the trainees' feedback. All trainees were trained in small groups (6 to 10 participants per workshop). The workshops consisted of mini-lectures, repeated micro teaching exercises and video-supported feedback concerning the following key-competencies: Communication of goals; methods to trigger interactivity; design of slides in power point presentations; effective feedback-techniques; and use of media, time-management, skills teaching, assessment methods (e.g. OSCE and others), evaluation and general presentation skills. The evaluation was based on two components: (A) trainees' scores in two objective structured ...

2005-09-01

87

Early and Late Bowel Complication Following Irradiation of Cancer of the Uterine Cervix-Whole Pelvis External Irradiation end High-Dose-Rate Interactively Irradiation  

International Nuclear Information System (INIS)

Cervix cancer is the most common female cancer in Korea. In spite of their relatively local invasive tendency, still 44% of patient will develop recurrent cancer This result suggests that more aggressive local treatment may increase the cure rate but increased complication risk also cannot be avoidable. Various institutions proposed different treatment regimen, but recommended dose were about 4500 cGy for whole pelvis and 8000 cGy at point A, even though they agreed that those doses may not be satisfactory for control of bulky disease. 96 cases of invasive cervical cancer, treated with postoperative or primary radiation therapy were analyzed to determine the complication rate and prognostic factor in our treatment regimen which is 500-1000 cGy higher than other institution. Mean follow up duration was 21 months. Symptomatic patients including mild but persistent abdominal discomfort was 46%, but only 1 patient (1%) had operative treatment because of incomplete obstruction of small ...

1989-06-01

88

Advanced radiation detector development: Advanced semiconductor detector development: Development of a oom-temperature, gamma ray detector using gallium arsenide to develop an electrode detector  

Energy Technology Data Exchange (ETDEWEB)

The advanced detector development project at the University of Michigan has completed the first full year of its current funding. Our general goals are the development of radiation detectors and spectrometers that are capable of portable room temperature operation. Over the past 12 months, we have worked primarily in the development of semiconductor spectrometers with {open_quotes}single carrier{close_quotes} response that offer the promise of room temperature operation and good energy resolution in gamma ray spectroscopy. We have also begun a small scale effort at investigating the properties of a small non-spectroscopic detector system with directional characteristics that will allow identification of the approximate direction in which gamma rays are incident. These activities have made use of the extensive clean room facilities at the University of Michigan for semiconductor device fabrication, and also the radiation measurement capabilities ...

1995-11-01

89

Percutaneous transhepatic biliary drainage for hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To evaluate the effect of PTBD in treating malignant biliary obstruction caused by hilar cholangiocarcinoma. Methods: We retrospectively analyzed the data of 103 patients(M:62,F:41)with malignant obstructive jaundice caused by hilar cholangiocarcinoma. After taking percutaneous transhepatic cholangiography, metallic stent or plastic external catheter or external-internal catheter for drainage was deployed and then followed up was undertaken with clinical and radiographic evaluation and laboratory. examination. Results: All patients went though PTBD successfully (100%). According to Bismuth classification, all 103 cases consisted of I type(N=30), II type (N=30), III type (N=26) and IV type (N=17). Thirty-nine cases were placed with 47 stents and 64 eases with drainage tubes. 4 cases installed two stems for bilateral drainage, 2 cases installed two stents because of long segmental strictures with stent in stent, 1 case was placed with three stents, and 3 cases installed stent ...

2007-10-01

90

Oil turbulence in the next decade. An essay on high oil prices in a supply-constrained world  

International Nuclear Information System (INIS)

A CIEP analysis of the recent development of demand and supply for crude oil indicates that the mismatch in supply and demand growth could cause tighter oil markets than we already experience today. In the World Energy Outlook 2007, the International Energy Agency (IEA) warned of a possible 'energy crunch'. But what was anticipated to happen in the first part of the next decade has been fast-forwarded to today, more than 5 years earlier, and could shake the very foundation of our energy systems if no action is undertaken. Without exaggeration, the recent developments in the international oil market are ground-breaking: a little over a year ago, in January 2007, the West Texas Intermediate crude oil price (WTI) traded for USD50 dollar a barrel. Within a year, the price doubled to USD100 per barrel in January 2008 and pushed through to over USD135 in June 2008, against the backdrop of the fresh market supposition about reaching a whopping USD200 per barrel in 2009. If this proves to be ...

98
100

The study of antiprotons and positrons in cosmic rays with the PAMELA spectrometer  

CERN Document Server

The study of antiprotons and positrons in cosmic rays with the PAMELA spectrometer

1998-01-01

101

Studies on the Permeability to Lipids and Lipoproteins of ...  

Science.gov (United States)

... Accession Number : AD0769178. Title : Studies on the Permeability to Lipids and Lipoproteins of Inflamed Skin Capillaries,. ...

102

ELECTRON MICROSCOPE STUDIES INTO THE ...  

Science.gov (United States)

ELECTRON MICROSCOPE STUDIES INTO THE MORPHOLOGY AND LOCALIZATION OF OMSK HEMORRHAGIC FEVER VIRUS IN INFECTED ...

1966-08-01

104

In vivo range of motion of the lumbar spinous processes  

UK PubMed Central (United Kingdom)

The study design included an in vivo laboratory study. The objective of the study is to quantify the kinematics of the lumbar spinous processes in asymptomatic patients during un-restricted functional...Full Text Available

2009-09-01

115

Study of Tibial Shaft Fractures in Children  

Science.gov (United States)

Tibial Shaft Fractures in Children

2010-11-09

133

Gestational Diabetes Follow Up Study  

Science.gov (United States)

Diabetes, Gestational; Postpartum Period

2009-10-19

141

Corrosion and histopathological studies on anode materials for implantable power sources. [In vivo corrosion studies on anode material  

Science.gov (United States)

The biocompatibility and corrosion resistance of various materials for use as sacrificial anodes in in vivo hybrid fuel cells were studied. Aluminium, zinc, and magnesium alloy AZ31B were studied, and the results are discussed.

1974-01-01

164

Mathematical Modeling and Optimization Studies on ...  

Science.gov (United States)

... 1]. Results and Discussion A cross section of liquid feed direct borohydride fuel cell model was created and studied. The ...

2010-05-12

166

A Study of the Geographic Origin, Education, and Experience ...  

Science.gov (United States)

... by starting and remaining in that size hotel. Another early study, conducted by Nailon (1968) sampled three general managers ...

1993-04-01

167

The use of healthy volunteers instead of patients to inform drug dosing studies: a [11C]raclopride PET study  

British Library Electronic Table of Contents (United Kingdom)

Rationale Receptor occupancy study has been performed to evaluate pharmacokinetic profiles in new antipsychotic drug development. While these findings highlight the value of positron emission tomography (PET) for dose-finding study, what is unclear is if it is necessary to conduct these studies in patients with schizophrenia or whether studies in healthy volunteers are adequate. Objectives To determine if it is necessary to conduct dopamine receptor occupancy studies in patients with schizophrenia or whether studies in healthy volunteers are adequate for dose-finding study, we compared the concentration?occupancy relationship in terms of EC50 between patients and healthy volunteers. Methods Ten healthy volunteers and eight patients with schizophrenia participated in the study. We measured ...

2011-01-01

168

Methodological Quality of Studies on the Measurement Properties of Neck Pain and Disability Questionnaires: A Systematic Review  

British Library Electronic Table of Contents (United Kingdom)

Objective: The aim of this study was to obtain an overview of the methodological quality of studies on the measurement properties of neck pain and disability questionnaires and to describe how well various aspects of the design and statistical analyses of studies on measurement properties are performed. Methods: A systematic review was performed of published studies on the measurement properties of neck pain and disability questionnaires. Two reviewers independently rated the quality of the studies using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist. This checklist was developed in an international Delphi consensus study. Results: A total of 47 articles were included on the measurement properties of 8 different questionnaires. The meth...

2011-01-01

169

(Feasibility study of the San Lorenzo River hydroelectric project)  

Science.gov (United States)

I travelled to San Jose, Costa Rica on July 8, 1990 to evaluate all of the completed elements of the ongoing feasibility study for the San Lorenzo River hydroelectric project. The feasibility study is being supported by ORNL under the Renewable Energy Applications and Training Project. The project is being studied for implementation by CONELECTRICAS, a consortium of rural electric cooperatives and the study itself is being conducted by BEL Engineering, a Costa Rican consulting firm under contract to CONELECTRICAS, USAID/PIC and NRECA.

1990-07-19

170

Using microarrays to identify positional candidate genes for QTL: the case study of ACTH response in pigs  

UK PubMed Central (United Kingdom)

BackgroundMicroarray studies can supplement QTL studies by suggesting potential candidate genes in the QTL regions, which by themselves are too large to provide a limited selection...Full Text Available

171

Using Geographic Information Systems for Exposure Assessment in Environmental Epidemiology Studies  

UK PubMed Central (United Kingdom)

Geographic information systems (GIS) are being used with increasing frequency in environmental epidemiology studies. Reported applications include locating the study population by geocoding addresses...Full Text Available

2004-06-01

172

Toxicity and carcinogenicity studies of boric acid in male and female B6C3F1 mice.  

UK PubMed Central (United Kingdom)

Toxicity and potential carcinogenicity studies of boric acid were investigated in mice to verify in a second rodent species that this was a noncarcinogenic chemical. Earlier chronic studies in rats...Full Text Available

1994-11-01

173

Theoretical Study of Tautomerization Reactions for the Ground and First Excited Electronic States of Adenine.  

Science.gov (United States)

Geometrical structures and energetic properties for different tautomers of adenine are calculated in this study, using multi-configurational wave functions. Both the ground and the lowest singlet excited state potential energy surfaces are studied. Four t...

2002-01-01

174

The Comprehensive Dialysis Study (CDS): A USRDS Special Study  

UK PubMed Central (United Kingdom)

Background and objectives: The Comprehensive Dialysis Study (CDS) aimed to understand factors contributing to physical, functional, and nutritional health status among patients starting dialysis.Design,...Full Text Available

2009-03-01

175

Study protocol. A prospective cohort study of unselected primiparous women: the pregnancy outcome prediction study  

UK PubMed Central (United Kingdom)

BackgroundThere have been dramatic changes in the approach to screening for aneuploidy over the last 20 years. However, the approach to screening for other complications of pregnancy...Full Text Available

176

Socio-demographic disparity in oral health among the poor: a cross sectional study of early adolescents in Kilwa district, Tanzania  

UK PubMed Central (United Kingdom)

BackgroundThere is a lack of studies considering social disparity in oral health emanating from adolescents in low-income countries. This study aimed to assess socio-demographic...Full Text Available

177

Prevalence of Ocular Fundus Pathology in Patients with Chronic Kidney Disease  

UK PubMed Central (United Kingdom)

Background and objectives: The objective of this study was to describe the prevalence of ocular fundus pathology in the Chronic Renal Insufficiency Cohort (CRIC) study, a multicenter, longitudinal study...Full Text Available

2010-05-01

178

Multicenter Case-Control Study on Restless Legs Syndrome in Multiple Sclerosis: the REMS Study  

UK PubMed Central (United Kingdom)

Study objectives:To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors.Design:Prospective,...Full Text Available

2008-07-01

179

Most Antidepressant Use in Primary Care Is Justified; Results of the Netherlands Study of Depression and Anxiety  

UK PubMed Central (United Kingdom)

BackgroundDepression is a common illness, often treated in primary care. Many studies have reported undertreatment with antidepressants in primary care. Recently, some studies also...Full Text Available

180

Molecular and clinico-pathological markers in rectal cancer: a tissue micro-array study  

UK PubMed Central (United Kingdom)

AimsThe aims of the study were to study the effect of pre-operative treatment on the expression of tumour-related proteins and to correlate the expression of these...Full Text Available

2009-02-01

181

Measuring quality of care in psychiatric emergencies: construction and evaluation of a Bayesian index.  

UK PubMed Central (United Kingdom)

OBJECTIVE. This study was conducted to determine whether an index for measuring quality of care for psychiatric emergencies is reliable and valid. DATA SOURCES/STUDY SETTING. The study used primary...Full Text Available

1993-06-01

182

Gender differences in disability after sickness absence with musculoskeletal disorders: five-year prospective study of 37,942 women and 26,307 men  

UK PubMed Central (United Kingdom)

BackgroundGender differences in the prevalence and occupational consequences of musculoskeletal disorders (MSDs) are consistently found in epidemiological studies. The study investigated...Full Text Available

183

Exposure to dioxin and nonneoplastic mortality in the expanded IARC international cohort study of phenoxy herbicide and chlorophenol production workers and sprayers.  

UK PubMed Central (United Kingdom)

The authors studied noncancer mortality among phenoxyacid herbicide and chlorophenol production workers and sprayers included in an international study comprising 36 cohorts from 12 countries followed...Full Text Available

1998-04-01

184

Electrophysiological Study and Catheter Ablation with 3D Mapping  

Medline Plus

... see and electrophysiological study and catheter ablation with 3D mapping. During the procedure, doctors look at the ... perform a electrophysiology study with ablation, using our 3D mapping system. Keep in mind, that during the ...

185

Dietary factors related to body weight in adult Vietnamese in the rural area of Haiphong, Vietnam: the Korean Genome and Epidemiology Study (KoGES)  

UK PubMed Central (United Kingdom)

The objectives of this study were to examine the association between dietary factors and underweight and overweight adult Vietnamese living in the rural areas of Vietnam. A cross-sectional study of...Full Text Available

2010-06-01

186

Design and Operating Parameters for Emission Control Studies: ASARCO, El Paso, Copper Smelter.  

Science.gov (United States)

The report gives background design data for a specific copper smelter. The data is sufficiently detailed to allow air pollution control system engineering studies to be conducted. These studies will be concerned primarily with lean SO2 streams that curren...

1976-01-01

187

Delineation of the Middle Longitudinal Fascicle in Humans: A Quantitative, In Vivo, DT-MRI Study  

UK PubMed Central (United Kingdom)

Experimental and imaging studies in monkeys have outlined various long association fiber bundles within the temporoparietal region. In the present study the trajectory of the middle longitudinal fascicle...Full Text Available

2009-04-01

188

A critical review of studies of the association between demands for hospital services and air pollution.  

UK PubMed Central (United Kingdom)

Studies of the associations between air pollution and hospital admissions and emergency room use are reviewed, including studies of air pollution episodes, time-series analyses, and cross-sectional...Full Text Available

1993-07-01

189

The implications of tolerance system interpretation on past and present dimensional variability studies  

Energy Technology Data Exchange (ETDEWEB)

Dimensional variability studies and published dimensional variability standards have been used by the foundry industry for years as an indicator of the casting process` ability to produce uniform parts. These studies are an extremely useful tool in the continuous ``dimensional dialogue`` between foundries and customers. The nature of these studies, and of the current tolerancing systems used by casting designers, leaves room for some misinterpretation and misuse of these study results. This paper contains two important discussions. The first part explains exactly what these studies represent. Following this is a brief explanation on dimensional and geometric tolerances and how they communicate dimensional requirements.

1994-12-31

190

Conditional risk assessment of SNR 300 in case of an unprotected loss of flow accident  

International Nuclear Information System (INIS)

This paper gives a summary of a risk study assuming unprotected loss of flow (ULOF) in the SNR 300. This study was initiated in 1979/80 by the Karlsruhe Nuclear Research Center and performed in close cooperation with Science Applications Inc., Palo Alto, USA, and Interatom Company. Part of the results also was integrated in the 'Risk Related Analysis for the SNR 300' carried out by the Gesellschaft fuer Reactorsicherheit. The character of the study described here is similar to other risk studies like the Reactor Safety Study and the German Risk Study for Nuclear Power Plants. The objectives and the methodology of the analyses are described and its results are discussed. (orig./RW).

191

Chernobyl Studies Project. Working Group 7.0, environmental transport and health effects. Progress report, February 1994  

Energy Technology Data Exchange (ETDEWEB)

The focus of the Chernobyl Studies Project has now turned to the issue of health effects from the Chernobyl accident. Currently, we are involved in and making progress on the case-control and co-hort studies of thyroid diseases among Belarussian children. Dosimetric aspects are a fundamental part of these studies. We are working to implement similar studies in Ukraine. A major part of the effort of these projects is supporting these studies, both by providing methods and applications of dose reconstruction and by providing support and equipment for the medical teams.

1994-04-01

192

Study of the Electron Beam Dynamics in the Fermi @ Elettra Linac  

Energy Technology Data Exchange (ETDEWEB)

A study of the electron beam dynamics in the linac is conducted for the FERMI free electron laser (FEL) founded for construction at the Sincrotrone Trieste.

2006-07-19

193

Study of the Electron Beam Dynamics in the FERMI @ ELETTRALinac  

Energy Technology Data Exchange (ETDEWEB)

A study of the electron beam dynamics in the linac is conducted for the FERMI free electron laser (FEL) founded for construction at the Sincrotrone Trieste

2006-06-17

194

Studies for the Synthesis of Xenicane Diterpenes. A Stereocontrolled Total Synthesis of 4-Hydroxydictyolactone  

UK PubMed Central (United Kingdom)

The stereocontrolled total synthesis of 4-hydroxydictyolactone (4), a member of the xenicane diterpene family of natural products, is described. These studies feature the development...Full Text Available

2009-07-01

195

Prognostic Factors for Failure after Prostatectomy  

UK PubMed Central (United Kingdom)

Several randomized studies have been completed in prostate cancer that show a benefit to immediate postoperative treatment in patients undergoing prostatectomy. In one of the studies, there was even...Full Text Available

196

Prediction accuracy of a sample-size estimation method for ROC studies  

UK PubMed Central (United Kingdom)

Rationale and ObjectivesSample-size estimation is an important consideration when planning a receiver operating characteristic (ROC) study. The aim of this work was...Full Text Available

2010-05-01

197

Periodontal disease and spontaneous preterm birth: a case control study  

UK PubMed Central (United Kingdom)

BackgroundSeveral studies have suggested an association between periodontal disease and prematurity but this finding has not been consistently observed.MethodsCase...Full Text Available

198

Packaging, Storage, and Containerization Center: Reports ...  

Science.gov (United States)

... 9 SIMPLIFICATION STUDY RECOMMENDATIONS - MIL-STD-2073-1/2 ... SIMPLIFICATION STUDY RECOMMENDATIONS - MIL-STD-2073-1/2 ...

1993-12-01

199

Naltrexone and Combined Behavioral Intervention Effects on Trajectories of Drinking in the COMBINE study  

UK PubMed Central (United Kingdom)

ObjectiveCOMBINE is the largest study of pharmacotherapy for alcoholism in the United States to date, designed to answer questions about the benefits of combining...Full Text Available

2010-03-01

200

Lunar Geology  

Science.gov (United States)

Lunar Geology is the study of the moons crust, rocks, strata, etc. Lunar Geology tends to cover two broad areas of study; Maria (and/or Basins) and Highlands. ...

201

In-situ micro-FTIR study of thermal changes of organics in Tagish ...  

Science.gov (United States)

FT-IR spectroscopic studies of major organic matter in carbonaceous chondrites using microscopic technique and comparison with terrestrial kerogen. ...

202

If I Had - A Family Member with Metabolic Syndrome  

Medline Plus

... elevated blood sugar levels, but not full-blown diabetes. What are the keys to preventing the disease? ... been well studied, in a study called The Diabetes Prevention Program, in several thousand people with this ...

203

Fundamental study of heat transfer augmentation of tube inside surface by cascade smooth surface-turbulence promoters  

Science.gov (United States)

Fundamental study of heat transfer augmentation of tube inside surface by cascade smooth surface-turbulence promoters

1987-03-01

204

Flue gas desulfurization pilot study: summary of phase I and phase II reports  

Science.gov (United States)

The initial phase of this study consisted of a survey of existing FGD systems used on larger combustion processes in the NATO countries and Japan.

1980-04-01

205

Field studies among diverse biomes demonstrate that nitrogen ...  

Science.gov (United States)

Field studies among diverse biomes demonstrate that nitrogen concentration (% N) at leaf- and canopy-scales is strongly related to carbon uptake and cycling ...

206

Effects of phenoxybenzamine on bladder neck opening1  

UK PubMed Central (United Kingdom)

A study of the effects of the action of phenoxybenzamine on bladder neck opening during micturition is reported. Twenty patients with symptoms of prostatism but minimal prostatic enlargement were studied....Full Text Available

1980-05-01

207

ESR study in radiation damage in pyrimidines. 3-year comprehensive progress report  

International Nuclear Information System (INIS)

General mechanisms of radiation damage to biomolecules was studied by using substituted pyrimidines, particularly barbituric acid derivatives.

208

Department of the  

Wastenet

Waste Technology and Innovation Study Final Report ...Waste Technology and Innovation Study Final Report 21/18569/150554 ...Survey of waste and resource recovery related technology and innovation, including products and product uses

209

Coccygectomy with or without periosteal resection  

UK PubMed Central (United Kingdom)

The purpose of this study was to compare the clinical outcomes and wound complications in coccygectomy with or without subperiosteal resection. This retrospective study included 25 patients who underwent...Full Text Available

2010-04-01

210

Clinical Investigation Program, Reports Control Symbol MED ...  

Science.gov (United States)

... POG Cook, BA A Case Control Study of Childhood 147 8552(85) Rhabdomyosarcoma (0) POG COOK, BA Phase II Study of 6-Mercaptopurine ...

1988-10-01

211

Biomarker studies in northern Bohemia.  

UK PubMed Central (United Kingdom)

Studies were conducted in northern Bohemia to simultaneously evaluate personal exposures to air pollution in the form of respirable particles containing polycyclic aromatic hydrocarbons (PAHs) and biomarkers...Full Text Available

1996-05-01

212

Alternative fuel trucks case studies: Running line-haul trucks on ethanol  

Energy Technology Data Exchange (ETDEWEB)

This bulletin describes case studies of trucks operating on ethanol fuel. Cost, maintenance and repair, as well as fuel economy are discussed.

1996-10-01

213

Winter Air Quality Study  

Science.gov (United States)

... 15 minutes Time lapse video Time Lapse Recorder (Panasonic) SVHS 4-seconds

217

The studying of electron motion in crystal lattice by using computer  

International Nuclear Information System (INIS)

... 2007, 80 ?. 5. ?????? ?.?. Visual Basic-6.0, ??????, 2000, 449 ?. ????

2010-04-01

220

The beginning of a new science  

International Nuclear Information System (INIS)

The evolution of the study of extra-terrestrial neutrinos over the 45 years since their discovery.

223

The Application of Diffusion Approximations to the Study of ...  

Science.gov (United States)

... Descriptors : *QUEUEING THEORY, *APPROXIMATION ... MODELS, OPTIMIZATION, STOCHASTIC PROCESSES ... Categories : TERMINAL FLIGHT ...

228

Study on a limiting sensitivity of a betatron introscope  

International Nuclear Information System (INIS)

1975. USSR Zabrodskij, VA Nedavnij, SN INIS-mf--3677. Available from

1975-09-03

256

Progress in plasma research at IPJ and IPPLM, Poland  

International Nuclear Information System (INIS)

... E. The Andrzej Soltan Institute for Nuclear Studies, Otwock-Swierk (Poland)

2006-09-11

266

Magnetic forming studies  

Science.gov (United States)

Elastodynamic approach to measuring stress-strain relationship of uniaxially stressed wire, and

1967-01-01

268

Isopod Systematics and Evolution  

Science.gov (United States)

... inferences. Thatcher carries the banner for studies of isopod parasites of fishes of the Amazonian region. This fauna ... ...

273

High energy physics  

International Nuclear Information System (INIS)

The research of the CELLO collaboration is reviewed. After a description of the CELLO detector tests of QCD and hadronic final states by determination of the strong coupling constant and studies of inclusive production of electrons and muons in multihadronic events in e"+e"- annihilation are described. Then studies of deep inelastic e#gamma# scattering with lepton pair production and the study of the structure function of the photon are briefly described. Finally studies on QED processes are described together with tau decays. (HSI).

1983-11-01

276

Fundamental study on Fuji Computed Radiography (FCR) image  

International Nuclear Information System (INIS)

Japanese (Mar 1986). Japan Tomiyoshi, Tsukasa Kakoi, Iwao Fukushima,

1986-01-01

288

Environmental Economics  

Wastenet

environmental burden is studied by testing the Environmental Kuznets Curve hypothesis as well as application of statistical decomposition

291

Dynamic Study of Co-generator System Using EMTDC  

Energy Technology Data Exchange (ETDEWEB)

This paper deals with dynamic study of co-generator system with derived dynamic models of generator, excitation system, and turbine/governor from field tests. Mainly this study concentrates on frequency control by under-frequency relay. We simulates dynamic study of co-generator system using EMTDC. (author). 4 refs., 13 figs., 4 tabs.

2001-07-01

292

Diquarks in gamma-p Collisions at LHeC  

CERN Document Server

This note studies the single production of scalar or vector diquarks at the LHeC collider.

2011-01-01

303

Cell culture systems to study glial transformation  

Energy Technology Data Exchange (ETDEWEB)

The transformation of two different types of glial cells has been studied using an in vivo-/in vitro model and a complete in vitro model. The purpose of the study and to define in vitro model systems is to study the the neoplastic transformation of pure populations of glial cells. Data are presented to demonstrate that the transformed cells are glial and tumorigenic. (ACR)

1980-01-01

304

Breath Test for Chemicals (Volatile Organic Compounds)  

Science.gov (United States)

Breath Tests; Human Volunteers; Pilot Study

2011-09-16

305

Biology of lichen communities in Antarctica.  

Science.gov (United States)

-Ecophysiological and floristic study of the lichen communities in .... Plasticity of the Lichen Catillaria corymbosa in Different Microhabitats of the ...

307

BOOKMARKS:  

Wastenet

Environmental Study/Action Team (NEST), UIPO Box 22025, Ibadan, Oyo-State, Nigeria ; tel/fax: +234 (

308

BIOCHEMISTRY BRANCH ABSTRACTS  

Science.gov (United States)

... The anti-tumor drugs used for these studies were: busulfan, cyclophosphamide, metho- trexate, vinblastine and 6-mercaptopurine. ...

1968-01-01

314

AN AES/XPS STUDY OF THE CHEMISTRY OF PALLADIUM ...  

Science.gov (United States)

... AT THE INTERFACE, A THIN OXIDE LAYER IS OBSERVED ALONG WITH POSSIBLE PALLADIUM SILICIDES. PALLADIUM ...

1981-02-01

321
353

A STUDY TO DETERMINE THE DEFORMATION ...  

Science.gov (United States)

... crystals and polycrystals. Nevertheless, explosive forming, magnetic forming, etc., are all high-strain-rate processes that ...

1963-04-01

361

 

Medline Plus

... 2009) Arrhythmia Electrophysiological Study and Catheter Ablation with 3D Mapping (Mercy Hospital, Miami, FL, 11/15/2007) ...

362

Case studies and educational aids survey. A research report  

Energy Technology Data Exchange (ETDEWEB)

A survey was conducted to determine the sources of buildings energy conservation case studies and educational aids available in Canada. In total 785 consultants, educational institutions, building developers, manufacturers and government agencies were contacted. The results of this survey provide an indication of those agencies in Canada most actively involved with energy conservation in buildings, a listing of those agencies in Canada having case study information and/or educational aids materials available related to energy conservation in buildings, and a broad description of the subject area of the case studies and educational aids listed. The results of this study are intended to provide a source listing of energy conservation case studies and educational aids to the Buildings Energy Technology Transfer Program lead agencies and others conducting similar ...

1983-09-01

363

Brookhaven National Laboratory Coastal Meteorology Program, 1972-1983  

Energy Technology Data Exchange (ETDEWEB)

Research conducted at Brookhaven National Laboratory under the Coastal Meteorology and Diffusion Research Program from 1972 to 1983 is summarized by the following study areas: Diffusion Studies, Boundary Layer Studies, Coastal Meteorology Studies, Air-Sea Interaction Studies, Coastal Transport and Diffusion Climatology, Seabreeze Modeling and Instrument Development, all supported by the US Department of Energy. Studies supported by the Nuclear Regulatory Commission, the National Science Foundation and the American Petroleum Institute are also described. A summary of a Workshop on Coastal Atmospheric Transport Processes, an account of studies in progress, recommendations for future research and a description of facilities and instrumentation available are also included. A list of all publications and presentations prepared as part of the ...

1983-06-01

364

Guidelines for Reporting Reliability and Agreement Studies (GRRAS) were proposed  

British Library Electronic Table of Contents (United Kingdom)

Objective: Results of reliability and agreement studies are intended to provide information about the amount of error inherent in any diagnosis, score, or measurement. The level of reliability and agreement among users of scales, instruments, or classifications is widely unknown. Therefore, there is a need for rigorously conducted interrater and intrarater reliability and agreement studies. Information about sample selection, study design, and statistical analysis is often incomplete. Because of inadequate reporting, interpretation and synthesis of study results are often difficult. Widely accepted criteria, standards, or guidelines for reporting reliability and agreement in the health care and medical field are lacking. The objective was to develop guidelines for reporting reliability and...

2011-01-01

365

Free radicals and their transformations in irradiated proteins  

International Nuclear Information System (INIS)

Experimental investigation data are systematized of free radical states and processes in irradiated proteins. The investigation is performed by the radiospectral methods. Results are discussed in detail of the study of free radicals electronic structure of amino acids, peptides and proteins formed by the action of ionizing radiation. The specificity is stressed of the study of monocrystalls of these compounds by the method of electronic paramagnetic resonance. The nature is also studied of primary centres formed under the effect of radiation on biologically important compounds and their subsequent reactions in solid and liquid solutions. Ion-radical states of different functional groups of the protein molecule are studied. Prospects of the study and the role of anion-radicals in biological processes are discusses.

366

Terror management among Taiwanese: Worldview defence or resigning to fate?  

British Library Electronic Table of Contents (United Kingdom)

Terror management theory (TMT) proposes that people who are reminded of their mortality should be motivated to defend their cultural worldview. Studies 1 and 2 examined whether the TMT worldview defence-buffering effect found in Western cultures could be generalized to Asians in Taiwan. No such effect was found in the present studies. This non-significant result was robust when either a stronger distraction task was used (study 1) or when a subliminal manipulation of mortality salience was utilized (study 2). A meta-analysis, including 24 TMT experiments in East Asia, was also conducted (study 3). The average effect size (d = 0.11, r = 0.055) of worldview defence among these experiments was not significantly different from zero. Study 4 found that mortality salience manipulation also did n...

2010-01-01

367

Technical design aspects of Feasibility Study-II  

Energy Technology Data Exchange (ETDEWEB)

Feasibility Study-II examined a high-performance Neutrino Factory providing 1 x 10{sup 20} neutrinos per year aimed at a long-baseline detector. The Study was sponsored jointly by BNL and the Neutrino Factory and Muon Collider Collaboration ration (MC) and is based on a 1 MW proton driver operating at 24 GeV, i.e., an upgraded version of the AGS accelerator. Compared with the earlier FNAL-sponsored study (Feasibility Study-I), there is a sixfold improvement in performance. Here we describe details of the implementation of Study-II concepts and discuss their efficacy. Alternative approaches that will be pursued in follow-on R and D activities are also described briefly.

2001-08-15

368

Scientific report 1997; Rapport scientifique 1997  

Energy Technology Data Exchange (ETDEWEB)

In this book are found technical and scientific papers on the main works of the Direction of the Fuel Cycle (DCC) in France. The study fields are: the up-side of the nuclear fuel cycle with theoretical studies (plasma simulation) and technological developments and instrumentation (lasers diodes, carbides plasma projection, carbon 13 enrichment); the down-side nuclear fuel cycle with theoretical studies (ion Eu{sup 3+} complexation simulation, decay simulation, uranium and plutonium diffusion study, electrolyser operating simulation), scenario studies ( recycling, wastes management), experimental studies; dismantling and cleaning (soils cleaning, surface-active agent for decontamination, fault tree analysis); analysis with expert systems and mass spectrometry. (A.L.B.)

1998-07-01

369

Industrial hazardous wastes in Finland - trends related to the waste prevention goal  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to analyse one of the goals of the latest National Waste Plan of Finland: the relative reduction of hazardous waste (HW) generation by 15% over the period 1992 to 2005.Official statistics and a national database of the annual reports of HW generators were used as one basis for this study. A case study was focused on a selection of HW classes that were considered to be typical to the metal workshop industry. These HW classes were combined to form functional HW groups for the purpose of forming time series. Trends at the company level were studied by performing interviews and by studying the environmental permit documents of about 50 companies.The total amount of HW reported in Finland increased by 133% over the studied period. Meanwhile the GDP of Finland gre...

2008-01-01

370

Facial soft tissue response to anterior segmental osteotomies: A systematic review  

British Library Electronic Table of Contents (United Kingdom)

Bimaxillary protrusion is prevalent among Asians and anterior segmental osteotomies are commonly used for its surgical correction. The objective of this study was to evaluate the soft tissue changes resulting from anterior segmental osteotomies. The electronic databases PubMed, Scopus and ISI Web of knowledge were searched for potentially eligible studies using a set of predetermined keywords. Full texts meeting the inclusion criteria were retrieved and their references were manually searched for additional relevant articles. The study details and outcome data of these reports were extracted using spreadsheets for comparison. The methodological quality of each study was assessed. Eleven studies met the inclusion criteria. Lateral cephalometry was used in all studies. A reduction of the lab...

2010-01-01

371

Economic study of a rural underground transmission system: A site-specific case study: Final report  

Energy Technology Data Exchange (ETDEWEB)

This report presents the data and results of a site specific case study comparing costs of an overhead line with an underground circuit traversing the same route. The costs used for the overhead line are actual numbers for a line scheduled to be built by a utility. The underground circuit costs were developed using the same criteria of line rating, contingencies, and location. Often cost comparisons between overhead and underground lines are made using figures taken from studies with widely varying assumptions. This project attempts to provide a comparison by studying the costs of overhead and underground lines following the same route and using the same design assumptions. Caution must be used, however, in extending the results of this study beyond its original intent. It is site-specific and may be representative of only one area of the country. 9 refs., 23 figs., 18 tabs.

1987-10-01

372

Association and expression study of synapsin III and schizophrenia  

British Library Electronic Table of Contents (United Kingdom)

The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter release and in synaptogenesis, suggesting a potential role in several neuropsychiatric diseases. The human SYN3 gene is located on chromosome 22q12-13, a candidate region implicated in previous linkage studies of schizophrenia. However, association studies of SYN3 and schizophrenia have produced inconsistent results. In this study, four SYN3 SNPs (rs133945 (-631 C>G), rs133946 (-196 G>A), rs9862 and rs1056484) were tested in three sets of totally 3759 samples that comprise 655 affected subjects and 626 controls in the Irish Case-Control Study of Schizophrenia (ICCSS), 1350 samples incorporating 273 pedigrees in the Irish Study of High D...

2009-01-01

373

beta- and gamma-decay studies of neutron-rich chromium, manganese, cobalt and nickel isotopes including the new isotopes $^{60}$Cr and $^{60g}$Mn  

CERN Document Server

beta- and gamma-decay studies of neutron-rich chromium, manganese, cobalt and nickel isotopes including the new isotopes $^{60}$Cr and $^{60g}$Mn

1987-01-01

375

Utilization of Carbon Monoxide (CO) Of the Flue Gas of a Hot Air Cupola Furnace Used for Melting.  

Science.gov (United States)

In this study the technical and economical possibilities of burning carbon monoxide (CO) of the flue gas and utilizing of the released heat in hot air cupola furnace used for melting have been studied. As basis for examining was burning of cleaned furnace...

1986-01-01

376

Tyrosine-derived polycarbonate membrane in treating mandibular bone defects. An experimental study  

UK PubMed Central (United Kingdom)

This study was designed to evaluate the suitability of a novel bioabsorbable material in treating bone defects. A poly(desaminotyrosyl-tyrosine-ethyl ester carbonate) (PDTE carbonate) membrane (thickness...Full Text Available

2006-10-22

377

Twenty Years of Public Health Research: Inclusion of Lesbian, Gay, Bisexual, and Transgender Populations  

UK PubMed Central (United Kingdom)

Objectives. This study determined to what extent lesbian, gay, bisexual, and transgender (LGBT) populations have been studied over the past 20 years of public health research.Methods....Full Text Available

2002-07-01

378

Trial of early nifedipine in acute myocardial infarction: the Trent study.  

UK PubMed Central (United Kingdom)

Over 30 months 9292 consecutive patients admitted to nine coronary care units with suspected myocardial infarction were considered for admission to a randomised double blind study comparing the effect...Full Text Available

1986-11-08

379

Transforaminal endoscopic surgery for symptomatic lumbar disc herniations: a systematic review of the literature  

UK PubMed Central (United Kingdom)

The study design includes a systematic literature review. The objective of the study was to evaluate the effectiveness of transforaminal endoscopic surgery and to compare this with open microdiscectomy...Full Text Available

2010-02-01

380

Transcriptional profile of isoproterenol-induced cardiomyopathy and comparison to exercise-induced cardiac hypertrophy and human cardiac failure  

UK PubMed Central (United Kingdom)

BackgroundIsoproterenol-induced cardiac hypertrophy in mice has been used in a number of studies to model human cardiac disease. In this study, we compared the transcriptional response...Full Text Available

381

Tissue Effect on Genetic Control of Transcript Isoform Variation  

UK PubMed Central (United Kingdom)

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

382

The prevalence and correlates of self-reported hearing impairment in the Ibadan Study of Ageing  

UK PubMed Central (United Kingdom)

AbstractThis cohort study of 1302 persons aged ≥65 years, conducted in the Yoruba-speaking regions of Nigeria, determines the prevalence and correlates of hearing impairment (HI)...Full Text Available

2010-08-01

383

The neurobiology of social attachment: A comparative approach to behavioral, neuroanatomical, and neurochemical studies*  

UK PubMed Central (United Kingdom)

The formation and maintenance of social bonds in adulthood is an essential component of human health. However studies investigating the underlying neurobiology of such behaviors have been scarce....Full Text Available

2008-11-01

384

The management of children with chronic fatigue syndrome-like illness in primary care: a cross-sectional study  

UK PubMed Central (United Kingdom)

BackgroundMost studies on children with chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) have been undertaken in tertiary care and little is known about their management...Full Text Available

2006-01-01

385

The influence of histological diagnosis on the postoperative complication rate following trans-urethral resection of prostate (TURP).  

UK PubMed Central (United Kingdom)

BACKGROUND: A number of studies have shown that the early mortality following TURP is higher for patients with prostate cancer than those with benign disease. This study examines the effect of the histological...Full Text Available

2002-11-01

386

The impact of water intake on energy intake and weight status: a systematic review  

UK PubMed Central (United Kingdom)

The effects of consuming water with meals rather than drinking no beverage or various other beverages remains under-studied. This systematic review of English language studies compared the effects...Full Text Available

2010-09-01

387

The effect of physician practice organization on efficient utilization of hospital resources.  

UK PubMed Central (United Kingdom)

OBJECTIVE. This study examines variations in the efficient use of hospital resources across individual physicians. DATA SOURCES AND SETTING. The study is conducted over a two-year period (1989-1990)...Full Text Available

1994-12-01

388

The associations between serum sex hormones, erectile function, and sex drive  

UK PubMed Central (United Kingdom)

Few studies have examined the association between sex hormone serum levels, erectile function, and sex drive. Using data from the Olmsted County Study of Urinary Symptoms and Health Status among...Full Text Available

2008-09-01

389

The Significance of Bladder Trabeculation in the Female Lower Urinary System: An Objective Evaluation by Urodynamic Studies  

UK PubMed Central (United Kingdom)

This study aimed to investigate the relationship between bladder trabeculation, urinary function, and the stage of pelvic organ prolapse (POP). The medical records of 104 patients with POP who underwent...Full Text Available

2005-10-31

390

The Relationship between Intimate Partner Violence, Rape and HIV amongst South African Men: A Cross-Sectional Study  

UK PubMed Central (United Kingdom)

ObjectiveTo investigate the associations between intimate partner violence, rape and HIV among South African men.DesignCross-sectional study involving...Full Text Available

391

The Non-linear Relationship between Gait Speed and Falls: The MOBILIZE Boston Study  

UK PubMed Central (United Kingdom)

OBJECTIVESAlthough several studies suggest that slow gait speed is a predictor of falls, it may also be a protective mechanism to prevent falls. Further, fast walking...Full Text Available

2011-06-01

392

The Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors Study: objectives, methods, and patient sample  

UK PubMed Central (United Kingdom)

ObjectivesThe objective of this paper is to describe the complex mixed-methods design of a study conducted to assess health-related quality of life (HRQOL) outcomes...Full Text Available

2008-07-01

393

Taking social relationships seriously: Lessons learned from the informed consent practices of a vaccine trial on the Kenyan Coast  

UK PubMed Central (United Kingdom)

AbstractIndividual informed consent is a key ethical obligation for clinical studies, but empirical studies show that key requirements are often not met. Common recommendations to strengthen...Full Text Available

2008-09-01

394

TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines  

UK PubMed Central (United Kingdom)

Recent studies suggest that TJ-41, a herbal drug, possesses chemotherapeutic effects. Accordingly, this study was undertaken to investigate the anticarcinogenic effects of TJ-41 on human breast cancer...Full Text Available

2009-01-01

395

Synergism between Prior Anisakis simplex Infections and Intake of NSAIDs, on the Risk of Upper Digestive Bleeding: A Case-Control Study  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this study was to investigate the relationship between prior Anisakis infections and upper gastrointestinal bleeding (UGIB), and its interaction...Full Text Available

396

Study of wood plastic composite in the presence of nitrogen containing additives  

Energy Technology Data Exchange (ETDEWEB)

Effect of nitrogen-containing additives in the study of wood plastic composites of MMA with simul and mango wood of Bangladesh has been investigated. Nine different additives were used and the additives containing carboamide group induce the highest tensile strength to the composite. (author).

1994-10-01

397

Study of wood plastic composite in the presence of nitrogen containing additives  

International Nuclear Information System (INIS)

Effect of nitrogen-containing additives in the study of wood plastic composites of MMA with simul and mango wood of Bangladesh has been investigated. Nine different additives were used and the additives containing carboamide group induce the highest tensile strength to the composite. (author).

1994-01-01

398

Study of wood plastic composite in the presence of nitrogen containing additives  

Science.gov (United States)

Effect of nitrogen-containing additives in the study of wood plastic composites of MMA with simul and mango wood of Bangladesh has been investigated. Nine different additives were used and the additives containing carboamide group induce the highest tensile strength to the composite.

1994-10-01

399

Study of particles trapped by a magnetic field  

Science.gov (United States)

A new type of radiation which occurs when particles are accelerated in the field of a longitudinal wave and in a transverse magnetic field is studied. The characteristics of such spontaneous radiation are obtained, and the influence of collective effects on the radiation is analyzed. The application of the findings to the theory of free electron lasers is discussed. 8 references.

1986-01-01

400

Studies on the mechanism of 1,3-butadiene-induced leukemogenesis: the potential role of endogenous murine leukemia virus.  

UK PubMed Central (United Kingdom)

Previous studies have revealed marked differences in the incidence of leukemia between rats and mice exposed to 1,3-butadiene that do not appear to be readily explained on the basis of pharmacokinetics...Full Text Available

1990-06-01

401

Studies on micellar fatty acid uptake by rat intestine in vitro with reference to the role of bile  

UK PubMed Central (United Kingdom)

1. The uptake and esterification to trigylceride of oleic acid in micellar form was studied in rat intestine in vitro. Sacs of the upper half of the everted intestine taken from bile...Full Text Available

1973-03-01

402

Studies on Poly(propylene fumarate-co-caprolactone diol) Thermoset Composites towards the Development of Biodegradable Bone Fixation Devices  

UK PubMed Central (United Kingdom)

The effect of reinforcement in the cross-linked poly(propylene fumarate-co-caprolactone diol) thermoset composites based on Kevlar fibres and hydroxyapatite was studied. Cross-linked poly(propylene...Full Text Available

2009-01-01

403

Studies on Inhibition of Intestinal Absorption of Radioactive Strontium  

UK PubMed Central (United Kingdom)

A method is reported which permits selective suppression of absorption of radioactive strontium from ingested food material, permitting the calcium to be available to the body. Studies were carried...Full Text Available

1964-08-08

404

Strategies for the production of genetically identical monkeys by embryo splitting  

UK PubMed Central (United Kingdom)

Genetically identical rhesus monkeys would have tremendous utility as models for the study of human disease and would be particularly valuable for vaccine trials and tissue transplantation studies where...Full Text Available

405

Spectroscopic studies of the type 2 and type 3 copper centres in the mercury derivative of laccase.  

UK PubMed Central (United Kingdom)

U.v.-visible-absorption and e.p.r. spectroscopy were used to study the type 2 and type 3 copper centres in the mercury derivative of laccase. After treatment with peroxide the mercury derivative of...Full Text Available

1989-10-15

406

Solid state and materials research: metal-semiconductor interactions  

International Nuclear Information System (INIS)

This section of the report is concerned with the study of the metallisation, oxidation and doping of materials which are of importance to the micro-electronics industry. The Van de Graaff accelerator and radioactive tracers are used for studying surface and sub-surface behaviour of these materials.

407

Roles of curli, cellulose and BapA in Salmonella biofilm morphology studied by atomic force microscopy  

UK PubMed Central (United Kingdom)

BackgroundCurli, cellulose and the cell surface protein BapA are matrix components in Salmonella biofilms. In this study we have investigated the roles of these...Full Text Available

408

Risks of consumption of contaminated seafood: the Quincy Bay case study.  

UK PubMed Central (United Kingdom)

A recent EPA-sponsored study of sediment and seafood contamination in Quincy Bay revealed elevated levels of several complex organic pollutants frequently of concern in human health assessments. A seafood...Full Text Available

1991-01-01

409

Risk of hematological malignancies associated with magnetic fields exposure from power lines: a case-control study in two municipalities of northern Italy  

UK PubMed Central (United Kingdom)

BackgroundSome epidemiologic studies have suggested an association between electromagnetic field exposure induced by high voltage power lines and childhood leukemia, but null results...Full Text Available

410

Risk management in design engineering bids  

Energy Technology Data Exchange (ETDEWEB)

Accurate engineering cost estimates are critical in developing bids for new work, and for effective resource allocation and project control. This study reports on design estimating methods found in the literature, and on the results of two empirical studies of how estimating techniques are used in professional practice and their accuracy. The study found great reliance on a classic {open_quotes}activity analysis{close_quotes} approach to estimating design resources, and significant hazards in commonly used parametric techniques. The study found that project managers expect their estimates to be accurate (with 80% confidence interval) of between -10% to +25%. The study also found that actual bids between engineering firms had a much greater range (-40% to +45%) than can be explained by accuracy. Perhaps most importantly the study found that none of the sampled ...

1995-06-01

411

Risk factors associated with mental illness in Oyo State, Nigeria: A Community based study  

UK PubMed Central (United Kingdom)

BackgroundThe main objective of this study was to determine the prevalence and factors associated with mental illness in Oyo State at community level using the general health questionnaire...Full Text Available

412

Revisional Percutaneous Full Endoscopic Disc Surgery for Recurrent Herniation of Previous Open Lumbar Discectomy  

UK PubMed Central (United Kingdom)

Study DesignA retrospective study.PurposeTo determine the feasibility and effectiveness of revisional percutaneous full endoscopic discectomy for...Full Text Available

2011-03-01

413

Reverse Engineering of Gene Regulatory Networks: A Comparative Study  

UK PubMed Central (United Kingdom)

Reverse engineering of gene regulatory networks has been an intensively studied topic in bioinformatics since it constitutes an intermediate step from explorative to causative gene expression...Full Text Available

2009-01-01

414

Retrospective identification and characterization of mild cognitive impairment from a prospective population cohort  

UK PubMed Central (United Kingdom)

ObjectivesMild Cognitive Impairment (MCI) case-finding criteria have low specificity in general population studies. The present study retrospectively identifies cases...Full Text Available

2010-08-01

415

Religion as a Natural Phenomenon  

ScienceCinema

...same sort of handle ? religious that we have on global warming or energy policy or ...other words my claim is that we need to study religion the way we study global warming and all the other really serious phenomena on this planet ...

416

Radiographic monitoring of incidental abdominal aortic aneurysms: a retrospective population-based cohort study  

UK PubMed Central (United Kingdom)

BackgroundAn abdominal aortic aneurysm (AAA) that is identified when the abdomen is imaged for some other reason is known as an incidental AAA. No population-based studies have...Full Text Available

417

Psychopathological features of irritable bowel syndrome patients with and without functional dyspepsia: a cross sectional study  

UK PubMed Central (United Kingdom)

BackgroundIrritable bowel syndrome (IBS) and functional dyspepsia (FD) show considerable overlap and are both associated with psychiatric comorbidity. The present study aimed to...Full Text Available

418

Psychometric evaluation of a radio electric auricular treatment for stress related disorders: a double-blinded, placebo-controlled controlled pilot study  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this double-blind randomized study is to test the efficacy of a radio electric stimulator device using an auricular reflex therapy protocol for stress-related...Full Text Available

419

Properties of cellulose solutions in methylmorpholine N-oxide containing montmorillonite nanoparticles and of composite films thereof  

British Library Electronic Table of Contents (United Kingdom)

Rheological properties of moderately concentrated solutions of cellulose in methylmorpholine N-oxide-dimethylformamide mixtures containing hydrophilic montmorillonite nanoparticles were studied. Film composite materials were prepared, and their physicomechanical properties and structural organization were studied.

2011-01-01

420

Pregnant women's working conditions and their changes during pregnancy: a national study in France.  

UK PubMed Central (United Kingdom)

In a study of 2387 employed women who had worked for more than three months of their pregnancy the data were extracted from a survey carried out on a national sample of births in France in 1981. Manual,...Full Text Available

1987-04-01

421

Postoperative retention of urine: a prospective urodynamic study.  

UK PubMed Central (United Kingdom)

OBJECTIVE--To investigate the cause of post-operative retention of urine in elderly men. DESIGN--Prospective study. SETTING--Northern General Hospital, Sheffield. PATIENTS--32 consecutive men (median...Full Text Available

1991-04-13

422

Post traumatic stress symptoms and heart rate variability in Bihar flood survivors following yoga: a randomized controlled study  

UK PubMed Central (United Kingdom)

BackgroundAn earlier study showed that a week of yoga practice was useful in stress management after a natural calamity. Due to heavy rain and a rift on the banks of the Kosi river,...Full Text Available

423

Position-sensitive proportional counter for space-based X-ray imaging studies  

International Nuclear Information System (INIS)

ASTROSAT, India's first dedicated astronomy satellite is slated for launch in 2007. The primary science objective of ASTROSAT is to explore the Universe using broad-band instruments covering optical, UV, soft X-ray and hard X-ray studies

2005-03-01

424

Plasminogen-125I responses in dogs to a single injection of urokinase and typhoid vaccine and to vascular injury  

UK PubMed Central (United Kingdom)

In vivo plasminogen responses to various stimuli were studied. Plasminogen-125I was prepared and used first for metabolic studies of plasminogen in control dogs. The average results were:...Full Text Available

1972-06-01

425

Photochemical injury to the foveomacula of the monkey eye following argon blue-green panretinal photocoagulation.  

UK PubMed Central (United Kingdom)

PURPOSE: Visual loss following panretinal photocoagulation was found in the Diabetic Retinopathy and the Early Treatment Diabetic Retinopathy Studies. This study was designed to test the hypothesis...Full Text Available

2000-01-01

426

Perceived Entitlement to Pain-Related Support and Pain Catastrophizing: Associations with Perceived and Observed Support  

UK PubMed Central (United Kingdom)

Studies on the determinants of pain-related support are needed to enhance couples-based treatments for pain. The purpose of this study was to determine the extent to which pain catastrophizing...Full Text Available

2009-12-15

427

Pain and pain-related interference in adults with lower-limb amputation: Comparison of knee-disarticulation, transtibial, and transfemoral surgical sites  

UK PubMed Central (United Kingdom)

Pain and pain-related interference with physical function have not been thoroughly studied in individuals who have undergone knee-disarticulation amputations. The principal aim of this study...Full Text Available

2009-01-01

428

Ocular motility in alternating squints: an electro-oculographic study.  

UK PubMed Central (United Kingdom)

Ocular movements were studied electro-oculographically in 10 normal subjects and 10 patients with alternating strabismus. Fixation and pursuit movements and to a less extent the saccadic movements were...Full Text Available

1982-04-01

429

Non-agonistic familiarity decreases aggression in male Turkish hamsters, Mesocricetus brandti  

UK PubMed Central (United Kingdom)

In laboratory studies, hamsters (Mesocricetus spp.) exhibit intense male-male aggression, thus making them an excellent model system for studies of the functional and mechanistic...Full Text Available

2009-02-01

430

Myofibrillogenesis in the developing zebrafish heart: A functional study of tnnt2  

UK PubMed Central (United Kingdom)

Various hypotheses have been proposed to explain the molecule processes of sarcomere assembly, partially due to the lack of systematic genetic studies of sarcomeric genes in an in vivo...Full Text Available

2009-07-15

431

Mutagenicity studies in a tyre plant: in vitro activity of workers' urinary concentrates and raw materials.  

UK PubMed Central (United Kingdom)

The possible contribution to urinary mutagenicity of occupational exposures in the rubber industry was studied by assaying the urine concentrates of 72 workmen (44 smokers) employed in a tyre plant....Full Text Available

1985-07-01

432

Modulation of leg muscle function in response to altered demand for body support and forward propulsion during walking  

UK PubMed Central (United Kingdom)

A number of studies have examined the functional roles of individual muscles during normal walking, but few studies have examined which are the primary muscles that respond to changes in external...Full Text Available

2009-05-11

433

Model Study of Instant Vehicular Camouflage.  

Science.gov (United States)

A feasibility study to determine what materials and geometric systems would be required for fabrication of a camouflage system that would instantaneously cover a military vehicle in order to disrupt its characteristic shape or outline. The program involve...

1973-01-01

434

Metal atom diffusion in amorphous silica and at the silica surface. Progress report, December 1, 1982-December 1, 1983  

Energy Technology Data Exchange (ETDEWEB)

Objective is to study the effects of local structure, interatomic forces, and atom size on the mobility of metal atoms in amorphous silica and at the silica surface. EXAFS studies of Zn and Pt in silica are reported. (DLC)

1983-01-01

435

Malignant melanoma of the skin among workers in a telecommunications industry: mortality study 1976-83.  

UK PubMed Central (United Kingdom)

An incidence study of malignant melanoma of the skin (MMS), conducted previously among the workers of four plants of a large telecommunications industry located in Montreal, Canada, showed a standardised...Full Text Available

1992-10-01

436

Magnetic excitations studied with time-of-flight spectroscopy  

Energy Technology Data Exchange (ETDEWEB)

An introduction to time-of-flight neutron spectroscopy is presented in the context of the study of magnetic materials. Examples are taken from the class of rare earth and actinide magnetic materials known as `strongly correlated electron` systems. (author) 11 figs., 24 refs.

1996-11-01

437

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies  

UK PubMed Central (United Kingdom)

Recently, genome-wide association studies (GWAS) have linked the human LIN28B locus to height and timing of menarche [1-Full Text Available

2010-07-01

438

Investigating the spatial variability in incidence of coronary heart disease in the Gazel cohort: the impact of area socioeconomic position and mediating role of risk factors  

UK PubMed Central (United Kingdom)

Study objectiveThe study aim was to improve our understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD)...Full Text Available

2011-02-01

439

Innovation and survival: a case study in planning medical library services.  

UK PubMed Central (United Kingdom)

In the information age, information utilities like libraries are as sensitive to the stresses of change as any other organization. This article is a case study of a small, specialized medical library...Full Text Available

1998-10-01

440

Inferring Past Pesticide Exposures: A Matrix of Individual Active Ingredients in Home and Garden Pesticides Used in Past Decades  

UK PubMed Central (United Kingdom)

BackgroundIn retrospective studies of the health effects of home and garden pesticides, self-reported information typically forms the basis for exposure assessment. Study participants...Full Text Available

2007-02-01

441

Infant stepping: a method to study the sensory control of human walking  

UK PubMed Central (United Kingdom)

Stepping responses were studied in infants between the ages of 10 days and 10 months while they were supported to step on a slowly moving treadmill belt. Surface...Full Text Available

1998-03-15

442

In vivo study of chloroplast volume regulation.  

UK PubMed Central (United Kingdom)

This paper describes a new technique that can be used to study chloroplast volume regulation in vivo. Nuclear magnetic resonance spectroscopy was used to measure relative amounts of chloroplast water...Full Text Available

1992-05-01

443

Immunoglobulins in myasthenia gravis. Kinetic properties of the acetylcholine-receptor antibody studied during lymph drainage.  

UK PubMed Central (United Kingdom)

A specific immunoglobulin, the receptor antibody, can be found in most patients with myasthenia gravis. In order to study the kinetic properties of this antibody, serial determinations of receptor antibody,...Full Text Available

1978-10-01

444

Immortalizing the Complexity of Cancer Metastasis Genetic Features of Lethal Metastatic Pancreatic Cancer Obtained from Rapid Autopsy  

UK PubMed Central (United Kingdom)

The virtual lack of well-characterized metastatic pancreatic cancer tissues for study has limited systematic studies of the metastatic process of this deadly disease. To address this important...Full Text Available

2005-05-01

445

Identifying barriers to Papanicolaou smear screening in Korean women: Korean National Health and Nutrition Examination Survey 2005  

UK PubMed Central (United Kingdom)

ObjectiveThis study was conducted to provide a nationwide analysis on barriers to cervical cancer screening in Korea.MethodsData used for this study...Full Text Available

2010-06-01

446

How Missing Information in Diagnosis Can Lead to Disparities in the Clinical Encounter  

UK PubMed Central (United Kingdom)

Previous studies have documented diagnostic bias and noted that its reduction could eliminate misdiagnosis and improve mental health service delivery. Few studies have investigated clinicians'...Full Text Available

2008-11-01

447

Health and function of participants in the Long Life Family Study: A comparison with other cohorts  

UK PubMed Central (United Kingdom)

Individuals from families recruited for the Long Life Family Study (LLFS) (n= 4559) were examined and compared to individuals from other cohorts to determine whether the recruitment targeting longevity...Full Text Available

448

Genetic association between the COMT genotype and urinary levels of tea polyphenols and their metabolites among daily green tea drinkers  

UK PubMed Central (United Kingdom)

Available in vitro and animal studies have shown cancer protective effects of tea polyphenols. Recent study suggests a greater protective effect of green tea intake on breast cancer...Full Text Available

449

Five year prospective study of plasma renin activity and blood pressure in patients with longstanding reflux nephropathy.  

UK PubMed Central (United Kingdom)

Eight of 100 normotensive children who had pyelonephritic scarring secondary to urinary infection and vesicoureteric reflux were found in an earlier study to have increased plasma renin activity (PRA)....Full Text Available

1987-07-01

450

Fast Flux Test Facility Reactor Vessel Removal Study  

Energy Technology Data Exchange (ETDEWEB)

This study assesses the feasibility of removing the FFTF reactor vessel from its current location in the reactor cavity inside the Containment vessel to a transporter for relocation to a burial pit in the 200 Area.

2002-10-23

451

Factors influencing the in vitro interaction between immunoglobulins and isolated C1: a critical study  

UK PubMed Central (United Kingdom)

The C1 fixation test is widely used for the study of the interaction between immunoglobulins, their fragments and the complement system. Some factors influencing the apparent extent of the C1 fixation...Full Text Available

1978-05-01

452

Experimental study of axial and crossflow velocity in a 7-pin wire wrapped bundle  

Science.gov (United States)

The results of an experimental study of axial and crossflow velocity in a 7-pin wire wrapped bundle similar for FFTF fuel bundles are reported. The results are compared with the forced crossflow model of the COBRA-III C computer program. (JWR)

1974-02-01

453

Evaluation of Oral Administration of Adenine to Dogs and Primates.  

Science.gov (United States)

Little change was observed in primates fed 75 mg/kg adenine over the four-week period. Minimal tissue pathology was encountered upon completion of the study. In contrast to earlier studies in which oral feeding of adenine to dogs caused severe symptoms, a...

1974-01-01

454

Estimating the incidence of coeliac disease with capture-recapture methods within four geographic areas in Italy.  

UK PubMed Central (United Kingdom)

STUDY OBJECTIVE: To estimate the incidence rate of newly diagnosed cases of coeliac disease in Italy. DESIGN: This was a descriptive study of coeliac disease incidence in the period 1990-91. SETTING:...Full Text Available

1996-06-01

455

Estimating Missing Heritability for Disease from Genome-wide Association Studies  

UK PubMed Central (United Kingdom)

Genome-wide association studies are designed to discover SNPs that are associated with a complex trait. Employing strict significance thresholds when testing individual SNPs avoids false positives at...Full Text Available

2011-03-11

456

Epidermal keratinocytes do not activate peripheral T-cells: interleukin-10 as a possible regulator  

UK PubMed Central (United Kingdom)

The immunogenicity of allogeneic cultured human epidermal keratinocytes (cHEKs) has been studied in several models with contradictory results. We studied human T-cell activation in an in vitro...Full Text Available

2008-11-01

457

Electron Spin Resonance Studies of Ionic Permeability Properties of Thylakoid Membranes of Beta vulgaris and Avicennia germinans1  

UK PubMed Central (United Kingdom)

Measurement of intrathylakoid aqueous volumes by electron spin resonance spectroscopy was used to study ionic permeability properties of thylakoid membranes isolated from Beta vulgaris...Full Text Available

1985-05-01

458

Effects of bovine leukemia virus infection on production and reproduction in dairy cattle.  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine the effects of bovine leukemia virus (BLV) infection on production, reproduction and longevity in dairy cattle. The study population was a commercial Holstein...Full Text Available

1992-10-01

459

Effect of misonidazole pretreatment on nitrogen mustard-induced DNA cross-linking in mouse tissues in vivo.  

UK PubMed Central (United Kingdom)

In the present study we have used the alkaline elution technique to study the effect of misonidazole (MISO) on the initial amount of DNA cross-linking in various normal and neoplastic tissues of C3H...Full Text Available

1984-12-01

460

Effect of Peroxisome Proliferator-Activated Receptor Gamma Agonist (Pioglitazone) and Methotrexate on Disease Activity in Rheumatoid Arthritis (Experimental and Clinical Study)  

UK PubMed Central (United Kingdom)

Objective:To investigate the combined effect of both pioglitazone and methotrexate on disease activity of rheumatoid arthritis in a biphasic study; experimental and clinical.Methods:Experimentally:...Full Text Available

461

ESR studies of spin-labeled membranes aligned by isopotential spin-dry ultracentrifugation: lipid-protein interactions.  

UK PubMed Central (United Kingdom)

Electron spin resonance (ESR) studies have been performed on spin-labeled model membranes aligned using the isopotential spin-dry ultracentrifugation (ISDU) method of Clark and Rothschild. This method...Full Text Available

1994-12-01

462

Dual Beneficial Effects of (-)-Epigallocatechin-3-Gallate on Levodopa Methylation and Hippocampal Neurodegeneration: In Vitro and In Vivo Studies  

UK PubMed Central (United Kingdom)

BackgroundA combination of levodopa (L-DOPA) and carbidopa is the most commonly-used treatment for symptom management in Parkinson's disease. Studies have shown that concomitant...Full Text Available

463

Does the socioeconomic context explain both mortality and income inequality? Prospective register-based study of Norwegian regions  

UK PubMed Central (United Kingdom)

BackgroundStudies from various countries have observed worse population health in geographical areas with more income inequality. The psychosocial interpretation of this association...Full Text Available

464

Divorce, divorce rates, and professional care seeking for mental health problems in Europe: a cross-sectional population-based study  

UK PubMed Central (United Kingdom)

BackgroundLittle is known about differences in professional care seeking based on marital status. The few existing studies show more professional care seeking among the divorced...Full Text Available

465

Diesel engine exhaust and lung cancer: an unproven association.  

UK PubMed Central (United Kingdom)

The risk of lung cancer associated with diesel exhaust has been calculated from 14 case-control or cohort studies. We evaluated the findings from these studies to determine whether there is sufficient...Full Text Available

1995-09-01

466

Developing IT Infrastructure for Rural Hospitals: A Case Study of Benefits and Challenges of Hospital-to-Hospital Partnerships  

UK PubMed Central (United Kingdom)

This article presents a study identifying benefits and challenges of a novel hospital-to-hospital information technology (IT) outsourcing partnership (HHP). The partnership is an innovative response...Full Text Available

2008-07-01

467

DOD (Department of Defense) Acquisition: Case Study of the MILSTAR (Military Strategic and Tactical Relay) Satellite Communications System.  

Science.gov (United States)

The study of the Military Strategic and Tactical Relay (MILSTAR) program focuses on the role of the program manager and contracting officer in developing the acquisition strategy.

1986-01-01

468

Critical review of studies on atmospheric dispersion in coastal regions  

Energy Technology Data Exchange (ETDEWEB)

This study effort was required as a preliminary step prior to initiation of field measurements of atmospheric dispersion in coastal regions. The Nuclear Regulatory Commission (NRC) is in the process of planning an extensive field measurement program to generate data which will serve as improved data bases for licensing decisions, confirmation of regulations, standards, and guides, and for site characterizations. The study being reported here is an effort directed to obtaining as much information as is possible from existing studies that is relevant toward NRC's objectives. For this study, reports covering research and meteorological measurements conducted for industrial purposes, utility needs, military objectives, and academic studies were obtained and critically reviewed in light of NRC's current data needs. This report provides an interpretation of the extent of ...

1982-09-01

469

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study  

UK PubMed Central (United Kingdom)

Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully...Full Text Available

2010-07-01

470

Cobalt-57-bleomycin scanning of hila and mediastinum in patients with bronchial carcinoma: a prospective study.  

UK PubMed Central (United Kingdom)

Because the results with cobalt-57-bleomycin (57Co-bleo) as a tumour-seeking agent in patients with pulmonary tumours were promising, a prospective study was carried out to test the sensitivity and...Full Text Available

1976-12-01

471

Clinical and laboratory studies in patients with leprosy and enthesitis.  

UK PubMed Central (United Kingdom)

In a combined clinical, radiological, and laboratory study of 77 patients throughout the leprosy spectrum, 10 patients had an enthesitis which has not been described previously as far as is known and...Full Text Available

1990-09-01

472

Chronic lymphatic leukaemia and engine exhausts, fresh wood, and DDT: a case-referent study.  

UK PubMed Central (United Kingdom)

The effect of potential risk factors for chronic lymphatic leukaemia was evaluated in a case-referent study encompassing 111 cases and 431 randomised referents, all alive. Information on exposure was...Full Text Available

1988-01-01

473

Childhood cancer and overhead powerlines: a case-control study.  

UK PubMed Central (United Kingdom)

A case-control study has been carried out to examine the occurrence of childhood cancer in relation to the proximity of overhead power lines to a child's home address at birth and to the calculated...Full Text Available

1990-12-01

474

Case-control study of hydrocarbon exposures in patients with renal cell carcinoma.  

UK PubMed Central (United Kingdom)

A retrospective case-control study tested the hypothesis that exposure to hydrocarbon combustion products is associated with the development of renal cell carcinoma. One control per case, matched for...Full Text Available

1989-06-01

475

Case series of maxillary sinus augmentation with biphasic calcium phosphate: a clinical and radiographic study  

UK PubMed Central (United Kingdom)

PurposeThe aim of this study was to evaluate 3.5 years-cumulative survival rate of implants placed on augmented sinus using Osteon, a bone graft material, and to assess the height...Full Text Available

2011-04-01

476

Carboxymethylation of peat in 2-propanol  

British Library Electronic Table of Contents (United Kingdom)

The effects of the time and temperature of alkaline pretreatment and the time and temperature of the carboxymethylation of peat in 2-propanol on the concentration of carboxymethyl groups and the solubility of the resulting products in water and an aqueous alkali solution were studied. The viscosity characteristics of the aqueous and aqueous alkaline solutions of peat carboxymethylation products were studied.

2011-01-01

477

Candidate salivary biomarkers associated with alveolar bone loss: cross-sectional and in vitro studies  

UK PubMed Central (United Kingdom)

This cross-sectional study evaluated the association between radiographic evidence of alveolar bone loss and the concentration of host-derived bone resorptive factors (interleukin-1 beta, tumor...Full Text Available

2007-03-01

478

Calorimetric studies of the kinetic unfreezing of molecular motions in hydrated lysozyme, hemoglobin, and myoglobin.  

UK PubMed Central (United Kingdom)

Differential scanning calorimetric (DSC) studies of the glassy states of as-received and hydrated lysozyme, hemoglobin, and myoglobin powders, with water contents of < or = 0.25, < or...Full Text Available

1994-01-01

479

Bacterial indicators of risk of diarrhoeal disease from drinking-water in the Philippines.  

UK PubMed Central (United Kingdom)

Inadequate measures of water quality have been used in many studies of the health effects associated with water supplies in developing countries. The present 1-year epidemiological-microbiological study...Full Text Available

1991-01-01

480

Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study  

UK PubMed Central (United Kingdom)

IntroductionThe goal of this study was to identify serum markers that are modulated by treatment with golimumab with or without methotrexate (MTX) and are associated with clinical...Full Text Available

2010-01-01

481

Association between skin diseases and severe bacterial infections in children: case-control study  

UK PubMed Central (United Kingdom)

BackgroundSepsis or bacteraemia, however rare, is a significant cause of high mortality and serious complications in children. In previous studies skin disease or skin infections...Full Text Available

482

Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study  

UK PubMed Central (United Kingdom)

IntroductionTransfusion is a common treatment in pediatric intensive care units (PICUs). Studies in adults suggest that prolonged storage of red blood cell units is associated with...Full Text Available

2010-01-01

483

Association Study of Serine Racemase Gene with Methamphetamine Psychosis  

UK PubMed Central (United Kingdom)

Experimental studies have demonstrated that not only dopaminergic signaling but also glutamatergic/NMDA receptor signaling play indispensable roles in the development of methamphetamine psychosis. Our...Full Text Available

2011-03-01

484

Assessment of a bone biopsy technique for measuring tiludronate in horses: A preliminary study  

UK PubMed Central (United Kingdom)

This study assessed the feasibility of measuring tiludronate in horses using a minimally invasive bone biopsy technique. Eight horses were treated with intravenous (IV) tiludronate [1 mg/kg bodyweight...Full Text Available

2011-04-01

485

Asking the right questions: Scoping studies in the commissioning of research on the organisation and delivery of health services  

UK PubMed Central (United Kingdom)

Scoping studies have been used across a range of disciplines for a wide variety of purposes. However, their value is increasingly limited by a lack of definition and clarity of purpose. The UK's Service...Full Text Available

486

Army Corps as a Joint Task Force Headquarters.  

Science.gov (United States)

This study investigates the doctrinal guidance available to a corps headquarters if required to serve as ajoint task force headquarters and simultaneously be required to warfight the corps. The study contends that a corps being required to simultaneously ...

1997-01-01

487

Application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals  

UK PubMed Central (United Kingdom)

Model systems to study the effects of chemicals of environmental concern on bacterial and parasitic diseases as well as the immunosurveillance and destruction of transplantable tumor cells were described...Full Text Available

1982-02-01

488

Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing).  

UK PubMed Central (United Kingdom)

The mammalian reoviruses have provided a valuable model for studying the pathogenesis of viral infections of the central nervous system (CNS). We have used this model to study the effect of antibody...Full Text Available

1988-12-01

489

An Evaluation of the Value of Choice with Preschool Children  

UK PubMed Central (United Kingdom)

The current study examined the reinforcing effects of choosing among alternatives in a four-part evaluation. In the first study, initial-link responses in a concurrent-chains arrangement resulted in...Full Text Available

2006-01-01

490

Amorphous to crystalline phase transformation in Metglas reg-sign studied by Moessbauer spectroscopy  

International Nuclear Information System (INIS)

The authors present differential scanning calorimetry (DSC) and in situ Moessbauer spectroscopy results for Metglas ribbons, to which different heat treatments were made. The Curie temperature of the amorphous phase is determined and the evolution of the magnetic field of this phase is studied as a function of temperature

1997-12-01

491

Ak-Chin Indian Community Biomass Feasiiblity Study  

Energy Technology Data Exchange (ETDEWEB)

Study of the conversion of chicken litter to biogas for the production of energy. There was an additional requirement that after extracting the energy from the chicken litter the nutrient value of the raw chicken litter had to be returned to the Ak-Chin Farms for use as fertilizer in a form and delivery method acceptable to the Farm.

2005-12-31

492

Addressing the Question of the Effect of RBC Storage on Clinical Outcomes: The Red Cell Storage Duration Study (RECESS) (Section 7)  

UK PubMed Central (United Kingdom)

The question of whether storage of red blood cells (RBCs) alters their capacity to deliver oxygen and affects patient outcomes remains in a state of clinical equipoise. Studies of the changes...Full Text Available

2010-08-01

493

A prospective randomised study on the long-term effect of lumbar fusion on adjacent disc degeneration  

UK PubMed Central (United Kingdom)

The existence and importance of an accelerated adjacent segment disc degeneration (ASD) after lumbar fusion have previously not been demonstrated by RCTs. The objectives of this study were, to determine...Full Text Available

2009-08-01

494

A nested case-control study of maternal-neonatal transmission of hepatitis B virus in a Chinese population  

UK PubMed Central (United Kingdom)

AIM: To examine the determinants of maternal-neonatal transmission of hepatitis B virus (HBV).METHODS: A nested case-control study was conducted in Changsha, Hunan, People’s Republic...Full Text Available

2011-08-21

495

A chemical-modification approach to the olfactory code. Studies with a thiol-specific reagent  

UK PubMed Central (United Kingdom)

The effects of thiol-specific reagents on the amplitude of the electro-olfactogram (E.O.G.) responses elicited from frog olfactory mucosa by pulses of odorant vapours was studied. The impermeant thiol-specific...Full Text Available

1978-12-15

496

A case cohort study of suicide in relation to exposure to electric and magnetic fields among electrical utility workers.  

UK PubMed Central (United Kingdom)

OBJECTIVES--This case cohort study examines whether there is an association between exposure to electric and magnetic fields and suicide in a population of 21,744 male electrical utility workers from...Full Text Available

1996-01-01

497

A Meta-Analysis of Animal Studies on Disruption of Spatial Navigation by Prenatal Cocaine Exposure  

UK PubMed Central (United Kingdom)

Water-maze testing has been used to assess prenatal cocaine (PCOC)- induced deficits in behavioral studies of spatial navigation and memory abilities. Effects of PCOC in acquisition or in probe...Full Text Available

2007-01-01

498

A Longitudinal Study of Incarceration and HIV Risk Among Methadone Maintained Men and Their Primary Female Partners  

UK PubMed Central (United Kingdom)

This study examines the longitudinal relationship between personal and sexual partner incarceration and subsequent HIV risk behaviors among drug-involved men and their primary female sexual...Full Text Available

2011-02-01

499

A Controlled Challenge Study on Di(2-ethylhexyl) Phthalate (DEHP) in House Dust and the Immune Response in Human Nasal Mucosa of Allergic Subjects  

UK PubMed Central (United Kingdom)

BackgroundFew studies have yet addressed the effects of di(2-ethylhexyl) phthalate (DEHP) in house dust on human nasal mucosa.ObjectivesWe investigated...Full Text Available

2008-11-01

500

A Comparative Study of 25 (OH) Vitamin D Serum Levels in Patients with Multiple Sclerosis and Control Group in Isfahan, Iran  

UK PubMed Central (United Kingdom)

Objectives:There is no study about correlation between vitamin D serum level and multiple sclerosis (MS) in Iran. So in this survey, we investigated the serum level of 25-hydroxy...Full Text Available

2010-01-01