Wastenet

...broad range of experience in designing and building research and development laboratories for products such as vaccines, blood and sera, biological products, medical devices, solid dosage forms , highly potent products and cytotoxic material. We also have experience in a range of modular laboratories for TSE research, ...

UK PubMed Central (United Kingdom)

Friends and colleagues remember John N. Brady, Ph.D., Chief of the Virus Tumor Biology Section of the Laboratory of Cellular Oncology, who died much too young at the age of 57 on April 27, 2009 of colon...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Efforts during the past year by the US Department of Energy and the Electric Power Research Institute-funded laboratories to investigate the biological effects from electric fields are described in resume form. Investigations generally have been summarized with objectives, accomplishments of the past year, and some indication of projected studies.

Energy Technology Data Exchange (ETDEWEB)

Science and technology are at the heart of everything we do at the National Renewable Energy Laboratory, as we pursue innovative, robust, and sustainable ways to produce energy--and as we seek to understand and illuminate the physics, chemistry, biology, and engineering behind alternative energy technologies. This year's Research Review highlights the Lab's work in the areas of alternatives fuels and vehicles, high-performing commercial buildings, and high-efficiency inverted, semi-mismatched solar cells.

Energy Technology Data Exchange (ETDEWEB)

This publication provides a broad overview of the research programs and efforts being conducted, built, designed, and planned at Brookhaven National Laboratory. This work covers a broad range of scientific disciplines. Major facilities include the Alternating Gradient Synchrotron (AGS), with its newly completed booster, the National Synchrotron Light Source (NSLS), the High Flux Beam Reactor (HFBR), and the RHIC, which is under construction. Departments within the laboratory include the AGS department, accelerator development, physics, chemistry, biology, NSLS, medical, nuclear energy, and interdepartmental research efforts. Research ranges from the pure sciences, in nuclear physics and high energy physics as one example, to environmental work in applied science to study climatic effects, from efforts in biology which are a component of the human genome project to the study, production, and ...

Science.gov (United States)

The LLNL Chemical & Biological National Security Program (CBNP) provides science, technology and integrated systems for chemical and biological security. Our approach is to develop and field advanced strategies that dramatically improve the nation's capabilities to prevent, prepare for, detect, and respond to terrorist use of chemical or biological weapons. Recent events show the importance of civilian defense against terrorism. The 1995 nerve gas attack in Tokyo's subway served to catalyze and focus the early LLNL program on civilian counter terrorism. In the same year, LLNL began CBNP using Laboratory-Directed R&D investments and a focus on biodetection. The Nunn-Lugar-Domenici Defense Against Weapons of Mass Destruction Act, passed in 1996, initiated a number of U.S. nonproliferation and counter-terrorism programs including the DOE (now NNSA) Chemical and ...

Energy Technology Data Exchange (ETDEWEB)

This report summarizes the activities and major accomplishments for the Idaho National Laboratory Advanced Radiotherapy Research Program for calendar year 2004. Topics covered include boron analysis in biological samples, computational dosimetry and treatment planning software development, medical neutron source development and characterization, and collaborative dosimetry studies at the RA-1 facility in Buenos Aires, Argentina.

Energy Technology Data Exchange (ETDEWEB)

A total of forty participants were included in the exercise, including NOAA, USEPA, state, Australian, Canadian, Mexican and Argentinean laboratories. Two samples were sent by NRC to each participant: a contaminated marine sediment from the vicinity of New York Bay and a freeze dried mussel (Mytilus edulis) from Charlottenlund, Denmark. Laboratories were also asked to analyze two certified reference materials NIST SRM 1566a, and NRC BCSS-1. The elements to be determined were Al, Cr, Fe, Ni, Cu, Zn, As, Se, Ag, Cd, Sn, Hg, and Pb for both matrices, plus Be, Si, Mn, Sb, and Tl for the sediments. An accepted mean and confidence interval were calculated for each analyte in the two unknown samples. Laboratory biases were identified and an overall rating of superior, good, fair or others was assigned to each laboratory.

Energy Technology Data Exchange (ETDEWEB)

Gas-insulated systems employing SF/sub 6/ are utilized in a variety of applications in power delivery systems. Because electric arcs, sparks or corona can decompose SF/sub 6/ into by-products having chemical properties different from SF/sub 6/, environmental concerns arise regarding inadvertent human exposures to electrically-decomposed SF/sub 6/. Biological assays in our laboratory using mammalian cell culture systems have revealed that SF/sub 6/, spark-decomposed under specific experimental conditions, can produce cell death. Chemical analysis of spark-decomposed SF/sub 6/ has identified the major decomposition pathways and by-products. Biological testing of individual by-products or by-product mixtures has indicated that these major decomposition products may not account for the majority of the cell killing effects seen in our assays. Further experiments have suggested that S/sub 2/F/sub 10/ may be produced and ...

Energy Technology Data Exchange (ETDEWEB)

The feasibility of removing petroleum hydrocarbons from oil fields produced waters using biological treatment was evaluated under laboratory and field conditions. Based on previous laboratory studies, a field-scale prototype system was designed and operated over a period of four months. Two different sources of produced waters were tested in this field study under various continuous flow rates ranging from 375 1/D to 1,800 1/D. One source of produced water was an open storage pit; the other, a closed storage tank. The TDS concentrations of these sources exceeded 50,000 mg/l; total n-alkanes exceeded 100 mg/l; total petroleum hydrocarbons exceeded 125 mg/l; and total BTEX exceeded 3 mg/l. Removals of total n-alkanes, total petroleum hydrocarbons, and BTEX remained consistently high over 99%. During these tests, the energy costs averaged $0.20/bbl at 12 bbl/D.

Energy Technology Data Exchange (ETDEWEB)

The development of a capability to infer wind velocities simultaneously at a number of ranges along one direction in real time is described. The elastic backscatter lidar data used was obtained using the XM94 lidar, developed by Los Alamos National Laboratory for the US Army Chemical and Biological Detection Command. In some respects this problem is simpler than measuring wind velocities on meso-meteorological scales. Other requirements, particularly high temporal fidelity, have driven the development of faster software algorithms and suggested opportunities for the evolution of the hardware.

Energy Technology Data Exchange (ETDEWEB)

There is a well-known story about the blind man examining the elephant: the part of the elephant examined determines his perception of the whole beast. Perhaps bioinformatics--the shotgun marriage between biology and mathematics, computer science, and engineering--is like an elephant that occupies a large chair in the scientific living room. Given the demand for and shortage of researchers with the computer skills to handle large volumes of biological data, where exactly does the bioinformatics elephant sit? There are probably many biologists who feel that a major product of this bioinformatics elephant is large piles of waste material. If you have tried to plow through Web sites and software packages in search of a specific tool for analyzing and collating large amounts of research data, you may well feel the same way. But there has been progress with major initiatives to develop more computing power, educate biologists about computers, ...

Science.gov (United States)

For a long time, the skeleton was seen as an amorphous tissue of little biological interest. But

International Science & Technology Center (ISTC)

Commercial Production and Development, in Entomopathogenic Nematodes in Biological Control

Energy Technology Data Exchange (ETDEWEB)

Gas-insulated systems employing SF/sub 6/ are utilized in a variety of applications in power delivery systems. Because electric arcs, sparks or corona can decompose SF/sub 6/ into byproducts having chemical properties different from SF/sub 6/, environmental concerns arise regarding inadvertent human exposures to electrically-decomposed SF/sub 6/. Biological assays in our laboratory using mammalian cell culture systems have revealed that spark-decomposed SF/sub 6/ produces cell death, and the extent of cell killing increases with increasing spark energy. Chemical analysis of spark-decomposed SF/sub 6/ has identified the major decomposition pathways and byproducts, but biological testing of individual or byproduct mixtures has indicated that these major decomposition products do not contribute, in a significant fashion, to the cell lethality seen in our assays. Further experiments have suggested that S/sub 2/F/sub 10/ may be ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Adalimumab is a fully human monoclonal anti-tumor necrosis factor-a agent that is approved for the treatment of Crohn's disease. It has a good safety profile, injection site reactions being the most common adverse effect. We report a case of a 54-year-old woman with a 30-year history of Crohn's disease who developed achromic patches on the trunk and upper extremities after initiating treatment with adalimumab. Cutaneous biopsy confirmed diagnosis of vitiligo and laboratory testing ruled out thyroid disease. Concomitant occurrence of vitiligo and inflammatory bowel disease, although rare, has been described. A common autoimmune basis could explain this fact. Moreover, multiple cutaneous adverse effects have been described in the literature secondary to biologic treatments, includin...

British Library Electronic Table of Contents (United Kingdom)

A microcosm laboratory experiment was conducted to determine the impact of biological reworking by the ragworm Nereis diversicolor on the redistribution of particle-bound radionuclides deposited at the sediment-water interface. Over the course of the 40-day experiment, as much as 35% of a 137Cs-labelled particulate tracer deposited on the sediment surface was redistributed to depths of up to 11 cm by the polychaete. Three different reworking models were employed to model the profiles and quantify the biodiffusion and biotransport coefficients: a gallery-diffuser model, a continuous sub-surface egestion model and a biodiffusion model. Although the biodiffusion coefficients obtained for each model were quite similar, the continuous sub-surface egestion model provided the best fit to the data...

British Library Electronic Table of Contents (United Kingdom)

An important aspect of ecosystem sustainability is the ability to withstand and recover from disturbance or stress. In this study, we investigated the effect of a heat-disturbance on soil microbial biomass, microbial activity in response to the addition of organic acid (malate), and microbial community structure in a laboratory experiment. The soils investigated were from a jarrah (Eucalyptus marginata) forest that had undergone rehabilitation following bauxite mining 12 years previously. Soils from a full factorial of two field treatments; contour ripping induced micro-topography (mound or furrow) and prior exposure to prescription fire (burnt or non-burnt), were sampled and found to exhibit treatment-dependent differences in soil biological and chemical properties. Exposure of soil micro...

Energy Technology Data Exchange (ETDEWEB)

for 170 years, scientists have attempted to explain why consistent temporal patterns of death are observed among individuals within populations. Historical efforts to identify a `law of mortality` from these patterns ended in 1935 when it was declared that such a law did not exist. These empirical tests for a law of mortality were constructed using mortality curves based on all causes of death. We predicted patterns of mortality consistent with the historical concept of a law would be revealed if mortality curves for species were constructed using only senescent causes of death. Using data on senescent mortality for laboratory animals and humans, we demonstrate patterns of mortality overlap when compared on a biologically comparable time scale. The results are consistent with the existence of a law of mortality following sexual maturity. The societal, medical, and research implications of such a law are discussed.

UK PubMed Central (United Kingdom)

The evaluation of biological markers is recognized as necessary to the future of toxicology, epidemiology, and quantitative risk assessment. For biological markers to become widely accepted, their validity...Full Text Available

Science.gov (United States)

PMID:21370327

KoreaScience (Korea)

Full Text Available

UK PubMed Central (United Kingdom)

The development of colorimetry and spectroscopy in the nineteenth century is described. An account is given of the application of their techniques to biological chemistry during that period.

Energy Technology Data Exchange (ETDEWEB)

Constructed wetlands may be used for removal of high nutrient loads in greenhouse wastewater prior to discharge into the environment. Temperature affects both the physical and biological activities in wetland systems. Since nitrification and denitrification are temperature-dependent processes, effluent nitrate concentrations will fluctuate due to changes in air and wetland temperature. In a cold climate, constructed wetlands can function in a temperature-controlled, greenhouse environment year-round. This work evaluates four temperature treatments on nitrate removal rates in five planted and five unplanted laboratory-scale wetlands. Wetlands were supplied with a nutrient solution similar to the fertigation runoff solution (100 PPM nitrate-N) used in greenhouse crop production. A first-order kinetic model was used to describe experimental nitrate depletion data and to predict nitrate removal rate constants (k) in the wetlands planted with Iris ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

Complete text of publication follows. At the Geomagnetic Institute, in the Laboratory for paleomagnetism and archeomagnetism research and at the Geomagnetic Observatory, Grocka (GCK) during the period from November 2004 to February 2008 the researchers carried out experimental magnetic measurements of the total-intensity gradient of the magnetic field vector (changes in the total magnetisation vector) of various biomaterials. Measurements of the gradient total intensity of the magnetic field vector were carried out by GSM-19 magnetometers of high accuracy and recording resolution (accuracy: #DELTA#F=0.1 nT; sampling rate: 1-5 per second). During these experimental biomagnetic measurements samples of water, tissue, blood, cotton, wool, pitch and magnetite-powder were used. In this study, the part of the biomagnetic measurement results relate to the water, blood and tissue. The results of the measurements of gradient total-intensity of the magnetic field for the ...

Energy Technology Data Exchange (ETDEWEB)

The quantitative estimation of various trace element concentrations in medicinal plants is necessary for determining their effectiveness in treating various diseases and for understanding their pharmacological action. Elemental concentrations of some selected medicinal plants of north east India was measured by proton induced X-ray emission (PIXE) and proton induced {gamma}-ray emission (PIGE) techniques. PIXE measurements were carried out using 2.4 MeV collimated protons from the 3 MV tandetron accelerator of NCCCM, Hyderabad (India) while the PIGE measurements were carried out using 3 MeV protons from the same accelerator in the same laboratory. Accuracy and precision of the techniques were assured by analyzing certified reference materials in the same experimental conditions. Various elements of biological importance in man's metabolism were found to be present in varying concentrations in the studied medicinal plants and no toxic ...

Energy Technology Data Exchange (ETDEWEB)

Gas transmission pipelines are susceptible to both internal (gas side) and external (soil side) corrosion attack. Internal corrosion is caused by the presence of salt laden moisture, CO{sub 2}, H{sub 2}S, and perhaps O{sub 2} in the natural gas. Internal corrosion usually manifests itself as general corrosion. However, the presence of chlorides in entrained water also can lead to pitting corrosion damage. The electrochemical noise technique can differentiate general from localized corrosion and provide estimates of corrosion rates without external perturbation of the corroding system. It is increasingly being applied to field and industrial installations for in situ corrosion monitoring. It has been used here to determine its suitability for monitoring internal and external corrosion damage on gas transmission pipelines. Corrosion measurements were made in three types of environments: (1) aqueous solutions typical of those found within gas pipelines in equilibrium with th e corrosive ...

Energy Technology Data Exchange (ETDEWEB)

In field O{sub 3}-enrichment experiments increased herbivore densities have been reported, which could be due to negatively affected host location behavior of natural enemies. We addressed the impact of doubling background O{sub 3} on the host location of the parasitoid Cotesia plutellae by conducting 24-h trials in an open-air O{sub 3}-fumigation system during two consecutive years. Two circles (radii 1.40 and 4.00 m) of Plutella xylostella-infested potted cabbage plants were placed in the O{sub 3} and ambient plots. Female wasps were released into each plot from the center, and observed 5 times over a 24-h period to assess their host location capability. Thereafter, plants were kept in laboratory conditions until larvae pupation to determine parasitism rates. No significant differences were detected between ambient and O{sub 3}-enriched environments either in the number of wasps found in the field, or in the percentages of parasitized larvae. This suggests that ...

International Nuclear Information System (INIS)

The possibilities to design and prepare better and more organ-specific radiopharmaceuticals for diagnostic nuclear medicine has increased dramatically in the recent past with a deeper understanding of the relationships between chemical structure and biological activity. Whereas most of the research is performed in well-funded laboratories of industrialized countries, there are several developing countries with adequate resources and expertise as to undertake fruitful research in the field of radiopharmacy. With the aim of promoting advanced research in radiopharmacy by developing new radiodiagnostics agents, in particular, hepatobiliary imaging agents labelled with "9"9"mTc, and to facilitate exchange of information, the IAEA has established in 1983 the present Research Co-ordination Programme (CRP) with a duration of five years. The report includes detailed results obtained by all participants as well as novel preparation procedures for some ...

Energy Technology Data Exchange (ETDEWEB)

A Lawrence Livermore National Laboratory (LLNL) Management Pre-Start Review (MPR) Team was formed to independently verify the operational readiness of Building 368 (B368) Biosafety Level III (BSL-3) Facility to conduct research with biological pathogens and toxins including those considered Select Agents. Review objectives and criteria were developed from the DOE/NNSA and LLNL requirements. These were provided in the Implementation Plan for the Biosafety Level III (BSL-3) Facility Management Pre-Start Review (BSL-3 MPR) at Lawrence Livermore National Laboratory that was reviewed and approved by DOE/NNSA-LSO. The formal part of the LLNL MPR for the BSL-3 Facility was begun in August of 2005 but work on the MPR was stopped in October of 2005 due to the need for LLNL to reassess organizational and operational controls and respond to Centers for Disease Control and Prevention inquiries related to a shipping incident involving ...

Wastenet

...and biological processes acting on recruitment and post-recruitment EU-Agrinet - Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quality indicator ... Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quali EU-Agrinet - Project sheet: Genetic evaluation of European ...

Energy Technology Data Exchange (ETDEWEB)

Richmond Harbor is on the eastern shoreline of central San Francisco Bay and its access channels and several of the shipping berths are no longer wide or deep enough to accommodate modem deeper-draft vessels. The Water Resources Development Act of 1986 (PL99-662) authorized the US Army Corps of Engineers (USACE), San Francisco District to deepen and widen the navigation channels in Richmond Harbor. Several options for disposal of the material from this dredging project are under consideration by USACE: disposal within San Francisco Bay, at open-ocean disposal sites, or at uplands disposal sites. Purpose of this study was to conduct comprehensive evaluations, including chemical, biological, and bioaccumulation testing of sediments in selected areas of Richmond Harbor. This information was required by the Environmental Protection Agency (EPA) and USACE. Battelle/Marine Sciences Laboratory collected 20 core samples, both 4-in. and 12-in., to a ...

UK PubMed Central (United Kingdom)

The authors emphasize the importance of stability in biological standards and discuss the steps taken to ensure the stability of International Standards and the theoretical basis of the various stability...Full Text Available

UK PubMed Central (United Kingdom)

The basic biology of the menstrual cycle is a complex, coordinated sequence of events involving the hypothalamus, anterior pituitary, ovary, and endometrium. The menstrual cycle with all its...Full Text Available

Science.gov (United States)

The Liver Carcinogenesis Section uses the modern technologies of molecular biology, cell biology, protein chemistry and genetics to investigate the biochemical and genetic pathways involved in human liver cancer.

UK PubMed Central (United Kingdom)

Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease,...Full Text Available

International Nuclear Information System (INIS)

Protecting Earth and planets against the invasion of 'alien life forms' is not military science fiction, but it is the peaceful daily job of engineers and scientists of space agencies. 'Planetary Protection' is preventing microbial contamination of both the target planet and the Earth when sending robots on interplanetary space mission. It is important to preserve the 'natural' conditions of other planets and to not bring with robots 'earthly microbes' (forward contamination) when looking for 'spores of extra terrestrial life'. The Earth and its biosphere must be protected from potential extraterrestrial biological contamination when returning samples of other planets to the Earth (backward contamination). The NASA-Caltech Laboratory for Planetary Protection of Dr. Kasthuri Venkateswaran at the Jet Propulsion Laboratory (JPL) (California, USA) routinely monitors and characterizes the microbes of NASA spacecraft assembly ...

Science.gov (United States)

Human space travelers experience a unique environment that affects homeostasis and physiologic

International Nuclear Information System (INIS)

Short communication.

International Science & Technology Center (ISTC)

Natural Biologically Active HLDF6 Peptide as Potential Preparation for Correction of Different Drugabuse Forms

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

... biological variability body distribution kidneys labelled compounds lead 203

Science.gov (United States)

NASA's Ames Research Center awarded Ciencia, Inc., a Small Business Innovation Research contract to

Science.gov (United States)

PMID:21921169

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Science.gov (United States)

Situation Management is a rapidly developing science combining new techniques for data collection

Science.gov (United States)

It is possible that at some time in the future we might recreate a habitable climate on Mars

Science.gov (United States)

The aim of our experiment was the testing of effects of common ammunition on usable and slightly accessible biological tissue thereby to create fundamental simple biological model for trials of wounded ballistic. Like objective tissue was elected biological material - pork and beef hind-limbs, pork head, pork bodily cavity. It was discovered that objective tissue is able to react to singles types of shots in all spectrum results namely simple smooth penetration wound as well as splintery fracture in dependence on kind of using ammunition. Pork hind-limb was evaluated like the most suitable biological material for given object. PMID:17172163

Science.gov (United States)

... Tactical Electronic Warfare Division (Code 5700) Visualization Laboratory Transportable step frequency radar Vehicle development laboratory ...

Energy Technology Data Exchange (ETDEWEB)

This paper describes the structure of dynamic neuronal ensembles (DNEs). DNEs represent a new paradigm for learning, based on biological neural networks that use variable structures. We present a computational neural element that demonstrates biological neuron functionality such as neurotransmitter feedback absolute refractory period and multiple output potentials. More specifically, we will develop a network of neural elements that have the ability to dynamically strengthen, weaken, add and remove interconnections. We demonstrate that the DNE is capable of performing dynamic modifications to neuron connections and exhibiting biological neuron functionality. In addition to its applications for learning, DNEs provide an excellent environment for testing and analysis of biological neural systems. An example of habituation and hyper-sensitization in biological systems, using a neural ...

International Nuclear Information System (INIS)

A microcosm laboratory experiment was conducted to determine the impact of biological reworking by the ragworm Nereis diversicolor on the redistribution of particle-bound radionuclides deposited at the sediment-water interface. Over the course of the 40-day experiment, as much as 35% of a "1"3"7Cs-labelled particulate tracer deposited on the sediment surface was redistributed to depths of up to 11 cm by the polychaete. Three different reworking models were employed to model the profiles and quantify the biodiffusion and biotransport coefficients: a gallery-diffuser model, a continuous sub-surface egestion model and a biodiffusion model. Although the biodiffusion coefficients obtained for each model were quite similar, the continuous sub-surface egestion model provided the best fit to the data. The average biodiffusion coefficient, at 1.8 #+-# 0.9 cm"2 y"-"1, is in good agreement with the values quoted by other workers on the bioturbation ...

UK PubMed Central (United Kingdom)

Early on, intriguing biological activities were found associated with the EETs using in vitro systems. Although the EETs other than the 5,6-isomer, are quite stable chemically,...Full Text Available

UK PubMed Central (United Kingdom)

In this study, we report the physico-chemical and biological properties of a novel biodegradable composite scaffold made of nano-hydroxyapatite and natural derived polymers of chitosan and carboxymethyl...Full Text Available

UK PubMed Central (United Kingdom)

The polarity of biological mediums controls a host of physiological processes such as digestion, signaling, transportation, metabolism, and excretion. With the recent widespread use of near-infrared...Full Text Available

UK PubMed Central (United Kingdom)

The effective population size (N_e) is an important parameter in ecology, evolutionary biology and conservation biology. It is, however, notoriously difficult to estimate,...Full Text Available

UK PubMed Central (United Kingdom)

This study compared the effectiveness of collaborative group composition and instructional method on reasoning gains and achievement in college biology. Based on initial student reasoning ability (i.e.,...Full Text Available

UK PubMed Central (United Kingdom)

CF-23“The biggest stumbling block for biological sciences turned out to be synthetic organic chemistry” – Elias A. Zerhouni, Former NIH Director in Chemical...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

One of the central questions of molecular biology is the discovery of the semantics of DNA. This discovery relies in a critical way on a variety of expensive computations. In order to solve these computations, both parallel computers and special-purpose hardware play a major role.

UK PubMed Central (United Kingdom)

Current pesticide health risk assessments in the United States require the characterization of aggregate exposure and cumulative risk in the setting of food tolerances. Biologic monitoring can aggregate...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundNetwork visualization would serve as a useful first step for analysis. However, current graph layout algorithms for biological pathways are insensitive to biologically...Full Text Available

Science.gov (United States)

... A Rapid Biological Assessment of the Kaijende Highlands, Enga Province, Papua New Guinea. RAP Bulletin of Biological ... A Rapid Biodiversity Assessment of the Kaijende Highlands, Enga Province, Papua New...

Science.gov (United States)

... structure along an elevational gradient in Hawaiian honeycreepers reveals contrasting evolutionary responses to avian malaria. BMC Evolutionary Biology 8: ... ...

British Library Electronic Table of Contents (United Kingdom)

The term biological motion is often used by researchers studying the patterns of movement generated by living forms and in sports. We studied a pattern recognition system of motion in sport using biological motion data. Biological motion data are acquired using a 3D motion capture system. However, 3D motion capture systems are very expensive. In this article, a biological motion capture system was built using acceleration sensors. Our proposed system uses the technique of Gaussian fitting and regression analysis. We tested our proposed system in pattern recognition of outdoor tennis and its evaluations.

Science.gov (United States)

Promises of ubiquitous control of the physical environment by large-scale wireless sensor networks

Energy Technology Data Exchange (ETDEWEB)

We present high-quality X-ray scattering experiments on pure water taken over a temperature range of 2 to 77 C using a synchrotron beam line at the advanced light source (ALS) at Lawrence Berkeley National Laboratory. The ALS X-ray scattering intensities are qualitatively different in trend of maximum intensity over this temperature range compared to older X-ray experiments. While the common procedure is to report both the intensity curve and radial distribution function(s), the proper extraction of the real-space pair correlation functions from the experimental scattering is very difficult due to uncertainty introduced in the experimental corrections, the proper weighting of OO, OH, and HH contributions, and numerical problems of Fourier transforming truncated data in Q-space. Instead, we consider the direct calculation of X-ray scattering spectra using electron densities derived from density functional theory based on real-space configurations generated with ...

International Nuclear Information System (INIS)

In radiation processing of food, the product often has to be prepackaged to prevent microbial recontamination during and after irradiation. The packaging material is exposed to radiation during radiation processing and radiation stability is a key consideration in the selection of packaging materials. The effects of ionizing radiation on many food packaging materials at the dose levels recommended for food precessing can be minimized by selecting appropriate radiation resistant materials. It is important to select materials in which chemicals formed as a result of the radiation treatment do not migrate and interact with the food, affecting its organoleptic and toxicological aspects. It is also important to select materials in which the physical properties are not altered to the extent they cannot resist damage during commercial production, shipment and storage. Radiation treatment of food may be classified broadly into two categories: 1. Processes requiring doses less than 10 kGy; 2. ...

Energy Technology Data Exchange (ETDEWEB)

About ten years ago microbiologically influenced corrosion manifested on stainless steel pipes used with river water for cooling a chemical plant. The pipe material was similar to Type 316 L. After only six weeks of operation pinhole leaks occurred nearly simultaneously at several welded joints of the pipe. The material degradation was simulated in laboratory and field corrosion tests. Microbiologically influenced corrosion failures also appeared on the pipes of a tubular heat exchanger of duplex steel Type 31803 and on carbon and stainless steel pipes in industrial waste water purification plants after these plants had been modernized with a biological purification unit. The basics of microbiologically influenced corrosion phenomena and typical corrosion failures of pipes will be described. (orig.) [German] Vor etwa zehn Jahren sind in einer neu errichteten chemischen Produktionsanlage an einer mit Flusswasser beaufschlagten Kuehlwasserleitung ...

Energy Technology Data Exchange (ETDEWEB)

In FY-2000, Engineering at Lawrence Livermore National Laboratory faced significant pressures to meet critical project milestones, and immediate demands to facilitate the reassignment of employees as the National Ignition Facility (the 600-TW laser facility being designed and built at Livermore, and one of the largest R&D construction projects in the world) was in the process of re-baselining its plan while executing full-speed its technology development efforts. This drive for change occurred as an unprecedented level of management and program changes were occurring within LLNL. I am pleased to report that we met many key milestones and achieved numerous technological breakthroughs. This report summarizes our efforts to perform feasibility and reduce-to-practice studies, demonstrations, and/or techniques--as structured through our technology centers. Whether using computational engineering to predict how giant structures like suspension bridges will ...

Energy Technology Data Exchange (ETDEWEB)

Numerous studies have investigated degradation of individual endocrine disrupting compounds (EDCs) in lab or natural waters. However, natural variations in water matrices and mixtures of EDCs in the environment may confound analysis of the treatment efficiency. Because chemical based analytical methods cannot represent the combined or synergistic activities between water quality parameters and/or the EDC mixtures at environmentally relevant concentrations ({mu}g L{sup -1}-ng L{sup -1}), bioanalytical assessments of residual estrogenic activity in treated water were used to evaluate the performance of the UV based advanced oxidation process for estrogenic contaminants in water. Four EDCs including estradiol (E{sub 2}), ethinyl estradiol (EE{sub 2}), bisphenol-A (BPA) and nonylphenol (NP) were spiked individually or as a mixture at {mu}g L{sup -1}-ng L{sup -1} in laboratory or natural river water. The removal rates of estrogenic activity were quantitatively evaluated ...

Energy Technology Data Exchange (ETDEWEB)

Biological motors generally fall into two categories: (1) those that convert chemical into mechanical energy via hydrolysis of a nucleoside triphosphate, usually adenosine triphosphate, regarded as life's chemical currency of energy and (2) membrane bound motors driven directly by an ion gradient and/or membrane potential. Here we argue that electrostatic interactions play a vital role for both types of motors and, therefore, the tools of physics can greatly contribute to understanding biological motors.

British Library Electronic Table of Contents (United Kingdom)

The mechanisms underlying life machinery are still not completely understood. Something is known, something is ?probably? known, other things are still unknown. Scientists all over the world are working very hard to clarify the processes regulating the cell life cycle and bioinformaticians try to support them by developing specialized automated tools. Within the plethora of applications devoted to the study of life mechanisms, tools for the analysis and comparison of biological networks are catching the attention of many researchers. It is interesting to investigate why.

UK PubMed Central (United Kingdom)

Over the past 10 years, the Peruvian National Tuberculosis (TB) Program, the National Reference Laboratory (NRL), Socios en Salud, and US partners have worked to strengthen the national TB laboratory...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

There is increasing pressure to operate laboratory facilities in environmentally and financially sustainable ways. A key factor in achieving this goal is careful consideration of how energy is used by the buildings' ventilation system, both for conditioning air supplied to the laboratories and the energy used moving air through the building. Traditionally, laboratory energy use is treated as an engineering concern within the scope of the building's overall design and operation. However, this approach limits the involvement of key stakeholders in many important decisions and can lead to unexpected safety concerns for the laboratory's users. We believe that a broad view of the parties affected by a laboratory building's operations is necessary to avoid having the various stakeholders working...

Science.gov (United States)

as manufacturing plants and laboratories, including the Chemical Laboratory at the House of David in Benton Harbor, Michigan. Built in America: Historic Building Buildings Survey/...

Energy Technology Data Exchange (ETDEWEB)

The purpose of this statement of work (SOW) is to establish laboratory analytical criteria and requirements for radioactive airborne emissions measurement sample and/or analysis activities.

Energy Technology Data Exchange (ETDEWEB)

This document details monthly activities at the Savannah River Laboratory. Topics addressed are reactor operation; tritium facilities and production; separation operations; environmental concerns; and waste management. (FI)

Science.gov (United States)

Publications Science Highlights Researcher Profiles Internship Funding to push battery technology from Argonne Laboratory to marketplace Bookmark and Share (Download...

Energy Technology Data Exchange (ETDEWEB)

The ''biotechnology 2000'' project is supervised by the project sponsor ''biology, energy, ecology'' at Forschungszentrum Juelich on behalf of the Federal Ministry for Research and Technology. The project activities cover the development of techniques and methods, cell biology, gene structure and gene regulation, photosynthetic production processes, biological hydrogen production, synthetic biology, protein design, neurobiological research, biosystems, plant breeding, phytomedicine and plant protection, the biology of waste disposal methods, research into methods which replace animal experiments, biological safety research, technology risk assessment, and ethical aspects. A general survey introduces the promoted projects, and standardized data sheets briefly introduce the individual ...

Energy Technology Data Exchange (ETDEWEB)

Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds. Some biological activities (antimicrobial, anticonvulsant, schistosomicidal) are attributed to the chemical reactivity and consequent affinity of hydantoinic rings towards biomacromolecules. Therefore, knowledge about the chemistry of hydantoins has increased enormously. In this review, we present important aspects such as reactivity of hydantoins, acidity of hydantoins, spectroscopy and crystallographic properties, and biological activities of hydantoin and its derivatives. (author)

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A confocal microscopy imaging system was devised to selectively detect Second harmonic signals generated by biological tissues. Several types of biological tissues were examined using this imaging system, including human teeth, bovine blood vessels, and chicken skin. All these tissues generated strong second harmonic signals. There is considerable evidence that the source of these signals in tissue is collagen. Collagen, the predominant component of most tissues, is known to have second order nonlinear susceptibility. This technique may have diagnostic usefulness in pathophysiological conditions characterized by changes in collagen structure including malignant transformation of nevi, progression of diabetic complications, and abnormalities in wound healing.

UK PubMed Central (United Kingdom)

Why we sleep remains one of the enduring unanswered questions in biology. At its core, sleep can be defined behaviorally as a homeostatically regulated state of reduced movement and sensory...Full Text Available

Science.gov (United States)

-Evaluacion de la fotosintesis y respiracion de especies de macroliquenes significativas en la tundra antartica. -Estudio de las isoenzimas en liquenes ...

UK PubMed Central (United Kingdom)

The molecular structure, chemical properties, and biological function of the xyloglucan polysaccharide isolated from cell walls of suspension-cultured sycamore (Acer pseudoplatanus)...Full Text Available

UK PubMed Central (United Kingdom)

The WHO Expert Committee on Biological Standardization authorized the National Institute for Medical Research to establish an International Reference Preparation of Erythropoietin on the basis of the...Full Text Available

UK PubMed Central (United Kingdom)

Some biological effects of hypoglycin-A, a compound isolated from the fruit of Blighia sapida, have been investigated. Administration of this compound to animals caused drowsiness...Full Text Available

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During their catalytic cycle, proteins involved in biological signal transduction undergo unexpectedly large conformational changes, which are at the core of their biological functioning. Until now it has been extremely difficult to obtain experimental insight into the nature of these conformational changes. Mathematical modeling and time-resolved X-ray crystallography have resulted in probable routes along which these conformational changes may take place, but so far this fundamental biological phenomenon has hardly been tackled experimentally. Here, we report on an attempt to observe structural changes in Photoactive Yellow Protein with time-resolved small-angle neutron scattering using diffractometer D22 at the high-flux reactor of the Institut Laue-Langevin, Grenoble, France.

Science.gov (United States)

... kinematic model for the robots and designed ... theoretic approach for modeling mobile robot teamn formations". ... "UUV teams, control from a biological ...

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... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_sphenocephala/r_sphenocephala.html Page Contact Information: SESC Webmaster Page ... ...

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... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_grylio/r_grylio.html Page Contact Information: SESC Webmaster Page ... ...

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... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_capito/r_capito.html Page Contact Information: SESC Webmaster Page ... ...

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Orphan G protein-coupled receptors (GPCRs) are receptors lacking endogenous ligands. Found by molecular biological analyses, they became the roots of reverse pharmacology, in which receptors are attempted...Full Text Available

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... la polilla fueron importadas a la facilidad de cuarentena en el Laboratorio de Control Biológico de Florida, ... ...

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SummaryThe polarized nature of neurons as well as the size and density of synapses complicates the manipulation and visualization of cell biological processes that control synaptic...Full Text Available

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Motivation: Inference of haplotypes from genotype data is crucial and challenging for many vitally important studies. The first, and most critical step, is the ascertainment of a biologically...Full Text Available

International Nuclear Information System (INIS)

... School of Plant Biology. v. 23(2) p. 316-322. carbon dioxide absorption carbon

International Nuclear Information System (INIS)

The biological half-life of "1"3"7Cs in the total body of human subjects was determined in 23 individuals of Japanese male adult in their normal works by measuring amount of "1"3"7Cs in both their total body and daily urine in the same period. For the group, the value was determined by averaging the half-lives for individuals, by comparing the mean body burden and the mean daily urinary excretion, or by applying a curve fitting method to the body burden estimate. The biological half-life averaged 86 days, ranging from 50 to 161 days. The averages of the biological half-lives for the group were 83, 87 and 82 days in the different periods of observation. By the curve fitting method, 85 days was found for the group. The biological half-life for the individuals depended on both body weight and age, to a lesser extent, of the subjects. (author).

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High-throughput genomic and proteomic technologies have generated a wealth of publicly available data on ageing. Easy access to these data, and their computational analysis, is of great importance in...Full Text Available

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A tunable diode laser is used to obtain infrared spectra of carbon dioxide in biological materials. The spectral resolution is sufficient to readily distinguish differing isotopic species. The technique may prove useful in clinical tests.

UK PubMed Central (United Kingdom)

CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological activity, signal transduction via protein...Full Text Available

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... view on the utility of such attacks, see JH Rothschild, Tomorrow's Weapons ... Aum Shinrikyo may have had a stolen vaccine anthrax strain incapable ...

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Pseudomonas stutzeri is a nonfluorescent denitrifying bacterium widely distributed in the environment, and it has also been isolated as an opportunistic pathogen from humans. Over the...Full Text Available

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... Ceratophyllaceas Ceratophyllum doemesm 96 4 3 4 107 Convulivulacme Ipomea aquatica 13 13 Haloragaceae Myriophyflum trahycatpum 15 15 ...

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... BFS Breadth-First Search BIS Biological Immune System CCNA Cisco-Certified Network Associate CDIS Computer Defense Immune System ...

CERN Document Server

We investigate the profound relation between the equations of biological evolution and quantum mechanics by writing a biologically inspired equation for the stochastic dynamics of an ensemble of particles. Interesting behavior is observed which is related to a new type of stochastic quantization. We find that the probability distribution of the ensemble of particles can be decomposed into eigenfunctions associated to a discrete spectrum of eigenvalues. In absence of interactions between the particles, the out-of-equilibrium dynamics asymptotically relaxes towards the fundamental state. This phenomenon can be related with the Fisher theorem in biology. On the contrary, in presence of scattering processes the evolution reaches a steady state in which the distribution of the ensemble of particles is characterized by a Bose-Einstein statistics. In order to show a concrete example of this stochastic quantization we have solved ...

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... deposition evaporation fission products fluorides iodine 134 laboratory

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Short communication. 1 ref., 4 figs.

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Polycyclic Aromatic Hydrocarbons (PAHs) are an important and ubiquitous component of carbon-bearing

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PMID:12324492

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Health surveillance program This article outlines the principal components of quality control of laboratory rodents.

International Nuclear Information System (INIS)

To encourage the application of robotics technology for routine radiobench applications, a laboratory dedicated to the research and development of contained robotic systems is being constructed. The facility will have several robots located in laminar flow hoods, and the hoods are being designed to allow the possibility for multiple robots to work together. This paper presents both the design features of the hoods and the general layout of the laboratory, and also discusses an application of a robotic system for the routine nuclear counting of gamma tube samples. The gamma tube system is presently operating in one of the routine analysis laboratories. 5 figs.

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The book is divided into two approximately equal parts. The first four chapters are relatively lengthy and cover the basic principles of radiation biology, carcinogenesis and therapy, along with a brief introduction to radiological physics to orient the reader without background in this specialized related discipline. The remainder consists of twenty-four relatively brief chapters, each covering the radiation biology of a specific organ, tissue, or systems tissues, with emphasis on the tumorigenic and tumoricidal action of ionizing radiations.

UK PubMed Central (United Kingdom)

The application of kinetic probes that allow one to determine relative reactivities of biologically relevant substrates with oxidizing intermediates in the Fenton reagent (H2O2 plus Fe2+ in acidic aqueous...Full Text Available

International Nuclear Information System (INIS)

New standardization techniques of samples in multielement instrumental neutron-activation analysis (INAA) of biological materials (BM) are considered. New methodical developments of sample preparation techniques, BM tableting, creation of comparison standards and standardization of packing material are suggested. Correlated data on concentration of different elements in standard specimens-comparison standards are presented for mass INAA, that is: for phenol-formaldehyde resin-base and human blood-base synthetic standards. 7 refs.; 3 tabs.

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Constructive and combinatorial relationships between order-isomorphisms and order-equivalence classes within the generalized genetic code are presented, not only for the biologically relevant groups of order 4, but also for finite groups of arbitrary order. The main result is the derivation of the number (and types) or order-equivalence classes for a group of order n. Finally, an extension of this work to all biologically admissible alternative codes is discussed.

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This book presents the current knowledge about the effects of electromagnetic fields on living matter. The three-part format covers dielectric permittivity and electrical conductivity of biological materials; effects of direct current and low frequency fields; and effects of radio frequency (including microwave) fields. The parts are designed to be consulted independently or in sequence, depending upon the needs of the reader. Useful appendixes on measurement units and safety standards are also included.

International Nuclear Information System (INIS)

A survey is presented of studies dealing with radionuclide X-ray fluorescence analysis (RXFA) of impurities in the air, water, soil, sediments and biological materials, mainly blood, urine, hair, soft tissues and bones. Tabulated are lists of published works on RXFA of the air, water and biological materials. (ES).

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The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also ...

Science.gov (United States)

This study was designed to compare the levels of chromium (Cr) and manganese (Mn) in scalp hair, blood, and urine of night blindness in children age ranged (3-7) and (8-12) years of both genders, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure, was developed as a sample pretreatment, for the determination of Cr and Mn in biological samples of night blindness children. The proposed method was validated by using conventional wet digestion and certified reference samples of hair, blood and urine. The digests of all biological samples were analyzed for Cr and Mn by electrothermal atomic absorption spectrometry. The results indicated significantly higher levels of Cr, whilst low level of Mn in the biological samples (blood and scalp hair) of male and female night blindness children, compared with control subjects of both genders. These data present guidance to clinicians and ...

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Heat production in biological materials due to absorption of radiowaves and microwaves can be used in applications as diverse as cancer treatment and cooking. However, the hazards of overexposure range from hyperthermia to cataracts and internal burns. To maximize the clinical benefits and minimize potential hazards, the biological effects of radiowaves and microwaves must be understood. Dielectric measurements can be used to determine the extent of such effects in various applications and at various levels of exposure. The values of maximum permissible exposure levels that are likely to be recommended aeat production in biological materials due to absorption of radiowaves and microwaves can be used in applications as diverse as cancer treatment and cooking. However, the hazards of overexposure range from hyperthermia to cataracts and internal burns. To maximize the clinical benefits and minimize potential hazards, the ...

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The existence of problems with wild pigs (Sus scrofa) is nothing new to the Western Hemisphere. Damage by these introduced animals was reported as far back as 1505 by the early Spanish colonies in the Caribbean, where wild pigs were killing the colonists cattle. Droves of these animals also ravaged cultivated crops of maize and sugarcane on islands in the West Indies during this same time period. These wild pigs reportedly were very aggressive and often attacked Spanish soldiers hunting rebellious Indians or escaped slaves on these islands, especially when these animals were cornered. The documentation of such impacts by introduced populations of this species in the United States has subsequently increased in recent years, and continued up through the present (Towne and Wentworth. 1950, Wood and Barrett 1979, Mayer and Brisbin 1991, Dickson et al. 2001). In spite of a fairly constant history in this country since the early 1900s, wild pigs have had a dramatic recent increase in both ...

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A description of the FEL experiment underway at the 10 kA, 5 MeV Experimental Test Accelerator (ETA) is described. The facility has been designed to investigate the high-gain operation of an FEL.

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The CWDD injector has been shipped to Argonne National Laboratory, installed, and recommissioned. Commissioning progress, operational status, and future plans are reported. Operational experience at ANL is compared with that obtained at Culham.

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This report documents site remediation at ORNL, including ORNL site characterization technologies, waste management and robotics and automation of the laboratory for waste processing and analysis.

International Nuclear Information System (INIS)

The Subseabed Disposal Program has recently completed a 30-day, 0.286-scale laboratory simulation of an In Situ Heat Transfer Experiment (ISHTE), scheduled for eventual deployment in the deep ocean 600 nautical miles north of Hawaii. 10 figures.

UK PubMed Central (United Kingdom)

1. Interactions of pyrazole and ethanol were studied in three laboratory test procedures. They included sleeping time in mice, rotor rod balance in rats and lever pressing behaviour of rats. 2....Full Text Available

International Nuclear Information System (INIS)

This volume described in detail the Department's research and technology development activities and their funding at the Department's laboratories. It includes 166 Mission Activity Profiles, organized by major mission area, with each representing a discrete budget function called a Budget and Reporting (B ampersand R) Code. The activities profiled here encompass the total research and technology development funding of the laboratories from the Department. Each profile includes a description of the activity and shows how the funding for that activity is distributed among the DOE laboratories as well as universities and industry. The profiles also indicate the principal laboratories for each activity, as well as which other laboratories are involved. The information in this volume is at the core of the Strategic Laboratory Mission Plan. It enables a reader to ...

UK PubMed Central (United Kingdom)

In a combined clinical, radiological, and laboratory study of 77 patients throughout the leprosy spectrum, 10 patients had an enthesitis which has not been described previously as far as is known and...Full Text Available

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This Maintenance Improvement Plan has been developed for maintenance functions associated with the 222-S Laboratory. This plan is developed from the guidelines presented by Department of Energy (DOE) Order 4330.4B, Maintenance Management Program (DOE 1994), Chapter 11. The objective of this plan is to provide information for establishing and identifying WMH conformance programs and policies applicable to implementation of DOE Order 4330.4B guidelines. In addition, this maintenance plan identifies the actions necessary to develop a cost effective and efficient maintenance program at 222-S Laboratory. Maintenance activities are mainly going to be performed by existing maintenance organizations within Waste Management Federal Services of Hanford (WMH). Most maintenance performed at 222-S Laboratory is performed by the 222-S Laboratory maintenance organization. This 222-S Laboratory ...

Science.gov (United States)

Directional audio technology for headphone applications is being developed. A laboratory demonstration model of a real-time digital ...

Science.gov (United States)

... 5. EXPLODING BRIDGEWIRE INITIATION OF RDX WITH 50 MILLIJOUUS RM Hillyer, Naval Ordnance Laboratory, Corona, Calif. .... ...

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No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

Annual report of performance against FY2000 performance evaluation and fee aggreement.

Science.gov (United States)

Jet Propulsion Laboratory. California Institute of Technology. Pasadena, California. Energy and Water Conservation. Steve Rigdon. Facilities Energy Manager ...

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... Lincoln Laboratory Distribution Models for Optical Scintillation Due to Atmospheric Turbulence RR Parenti RJ Susiela Group 107 ...

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Information is presented concerning reactor research activities; isotope geology; NERC radiocarbon laboratory; teaching activities; and reactor operation.

DEFF Research Database (Denmark)

This paper presents the concept of a biological inspired reconfigurable hardware cell architecture which supports self-organisation and self-healing. Two fundamental processes in biology, namely fertilization-to-birth and cell self-healing have inspired the development of this cell architecture. In biology as well as in our hardware cell architecture it is the DNA which enables these processes. We propose a platform based on the electronic DNA (eDNA) and show through simulation, its capabilities as a new generation of robust reconfigurable hardware platforms. We have created a Java based simulator to simulate our self-organisation and self-healing algorithms and the results obtained from this looks promising.

British Library Electronic Table of Contents (United Kingdom)

Native to Southeast Asia, Hygrophila polysperma is an invasive aquatic weed of lotic habitats in the southern United States and Mexico. An increase in the number of water bodies invaded by hygrophila since 1990 suggests that current methods employed to control this weed are inadequate. Classical biological control may be a viable option for long term regulation of hygrophila in the invaded range. In this study, we used the Maximum Entropy Species Distribution Model (MaxEnt) to prioritize climatically suitable native habitats in India and Bangladesh for conducting exploratory surveys to collect biological control agents. In total, 164 point occurrences from the United States and Mexico and 20 predictor variables, including 19 bioclimatic variables and altitude, were used to predict the nati...

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The biological treatment process was selected by Gaz de France (GDF), the French national gas utility, for the de-pollution of an old gas works where the main pollutants are coal tars containing polycyclic aromatic hydrocarbons. Microorganism-based biological treatment techniques may involve bio-reactors, static ground knolls (where oxygen is brought through drains) and dynamic knolls (where oxygenation is carried out by turning up the soil). Issues on sampling, sorting, process testing, site preparation, process control, etc. are reviewed

British Library Electronic Table of Contents (United Kingdom)

Motivation: High-throughput transcriptomics, proteomics and metabolomics methods have revolutionized our knowledge of biological systems. To gain knowledge from comparative omics studies, strong data integration and visualization features are required. Knowledge gained from these studies is often available in the form of graphs, and their visualization is especially useful in a wide range of systems biology topics, including pathway analysis, interaction networks or gene models. Especially, it is necessary to compare biological models with measured data. This allows the identification of new models and new insights into existing ones. Results: We present MGV, a versatile generic graph viewer for multiomics data. MGV is integrated into Mayday (Battke et al., 2010). It extends Maydays visual...

British Library Electronic Table of Contents (United Kingdom)

Research and bioethical policies are increasingly seen to facilitate, rather than to impede, scientific progress. Bioethical structures, nonetheless, often fail to account for or to shape the specific social surrounds in which scientific research is conducted. In Taiwan, a perceived shortage in human biological donations threatens to hamper stem cell research progress. This paper considers the stalled national biobank project and the lack of a reliable embryo supply for stem cell research, and suggests that one must look beyond regulatory structures in seeking explanations for such shortages. Specific aspects of Taiwan's democratization and social changes combine with problematic relations between patients and physicians to shape the terrain upon which human biologicals are given or withhe...

British Library Electronic Table of Contents (United Kingdom)

In this article we evaluate a US Forest Service plan to mitigate damages from an invasive insect on public, forested land. We develop a dynamic model of infestation and control to explicitly account for biological interactions, baseline conditions, and uncertainty, thus creating a more complete picture of policy impacts than a static cost benefit analysis could provide. We combine the results of the dynamic model with an empirical study of nonmarket forest benefits to create a bioeconomic model of ecosystem management. Estimating the empirical model in a Bayesian framework allows us to treat the economic coefficients of the dynamic model as random variables. We specify distributions for the biological parameters and examine the effects of both biological and economic uncertainty on the pre...

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This statement summarizes Lawrence Livermore National Laboratory`s committment to making important scientific, technological, and business contributions to global sustainability. The quest has many aspects, some socio-political or economic and some technological, and some in which the soft and hard sciences become indistinguishable, as in visionary national strategies, like Holland`s, and futuristic regional and city development plans, like those of Kagoshima and Chattanooga.

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Negligent hazardous waste management has resulted in real threats to public health. The Federal Government has responded to the situation with laws and regulations aimed at the producers of hazardous waste, including clinical laboratories. The Resources Conservation and Recovery Act (RCRA) imposes controls on hazardous waste management through the Code of Federal Regulations (CFR). The Environmental Protection Agency (EPA) and the Department of Transportation (DOT) regulate these activities through 40 CFR and 49 CFR. Most clinical laboratories can operate satellite accumulation points and accumulate, store, transport, and dispose of waste in accordance with EPA and DOT regulations. Regulations pertaining to infectious waste, sure to affect many clinical laboratories, are being developed now by he EPA. The cradle to grave tracking system mandated by the Federal Government can be supplemented by state and local authorities ...

UK PubMed Central (United Kingdom)

Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration...Full Text Available

International Nuclear Information System (INIS)

Biological monitoring has been conducted in industrially impacted streams near US Department of Energy facilities in Tennessee and Kentucky for almost ten years. A comprehensive Biological Monitoring and Abatement Program, which was developed to meet National Pollutant Discharge Elimination System permit requirements, includes tasks on (1 ) toxicity testing; (2) bioaccumulation in aquatic and terrestrial biota; (3) bioindicators of fish health; and (4) fish, macroinvertebrate, and periphyton community surveys. These studies have been used successfully to characterize spatial trends and demonstrate temporal recovery resulting from remedial actions and pollution abatement activities, identify contaminant sources, and provide data for conducting ecological risk assessments. The program uses multiple lines of evidence to evaluate stream recovery and illustrates the importance of using an integrated approach when determining stream health. An ...

Science.gov (United States)

... such as biology, physics, geology, materials science, engineering, computer science, and mathematics ... expected to produce course and curricular materials that will be of national interest and widely ...

UK PubMed Central (United Kingdom)

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

UK PubMed Central (United Kingdom)

DNA methylation of cytosine residues is a widespread phenomenon and has been implicated in a number of biological processes in both prokaryotes and eukaryotes. This methylation occurs at the 5-position...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Methods and materials employed by NCL to reclaim treatment of overburden dumps in opencast projects are described. These involve controlling slope stability and erosion (for example by covering with geosynthetic composites or jute/coir mat) and installing a drainage system before planting trees, shrubs and grass. 1 photo.

Science.gov (United States)

Petroleum contamination of groundwater is widely recognized as a serious environmental problem. Toluene (methylbenzene) occurs naturally in crude oil and is commonly found as a contaminant in the subsurface as a result of waste disposal and storage activities. Biological transf...

UK PubMed Central (United Kingdom)

In recent years, the interest in the use of bacteria for biological control of plant-pathogenic fungi has increased. We studied the possible side effects of coating barley seeds with the antagonistic...Full Text Available

UK PubMed Central (United Kingdom)

Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficial renal effects of some medications, such as chelation therapy depend at least partially on the ability...Full Text Available

UK PubMed Central (United Kingdom)

The processes regulating telomere function have major impacts on fundamental issues in human cancer biology. First, active telomere maintenance is almost always required for full oncogenic transformation...Full Text Available

UK PubMed Central (United Kingdom)

Contemporary high dimensional biological assays, such as mRNA expression microarrays, regularly involve multiple data processing steps, such as experimental processing, computational processing, sample...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The article presents measures for the solution of construction-biological problems and for reducing the pollutant load of buildings. (HW) [Deutsch] Der Artikel berichtet ueber Massnahmen ueber Sanierung von baubiologischen Schwachstellen und Schadstoffbelastungen in Gebaeuden. (HW)

UK PubMed Central (United Kingdom)

Digital information flow within the intensive care unit (ICU) continues to grow, with advances in technology and computational biology. Recent developments in the integration and archiving of these...Full Text Available

UK PubMed Central (United Kingdom)

The impacts of climate change on crop productivity are often assessed using simulations from a numerical climate model as an input to a crop simulation model. The precision of these predictions reflects...Full Text Available

UK PubMed Central (United Kingdom)

Stem cells are expected to play a key role in the development and maintenance of organisms, and hold great therapeutic promises. However, a number of questions must be answered to achieve an...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Abstracts of research projects are presented in the following areas: measurements and special facilities; cellular and subcellular studies; physiology; behavior; environmental effects; modeling, scaling and dosimetry; and high voltage direct current. (ACR)

UK PubMed Central (United Kingdom)

BackgroundDifferent microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little overlap,...Full Text Available

UK PubMed Central (United Kingdom)

Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence...Full Text Available

UK PubMed Central (United Kingdom)

Organisms in the genus Mycobacterium cause a variety of human diseases. One member of the genus, M. ulcerans, causes a necrotizing skin disease called Buruli ulcer....Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing within...Full Text Available

UK PubMed Central (United Kingdom)

Voxel-based prescriptions of deliberately non-uniform dose distributions based on molecular imaging, so-called dose painting or theragnostic radiation therapy, require specification of a transformation...Full Text Available

UK PubMed Central (United Kingdom)

Motivation: The identification of gene regulatory modules is an important yet challenging problem in computational biology. While many computational methods have been proposed to identify...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The overall objective of this project was to use molecular genetics to develop strains of bacteria with enhanced ability to remove sulfur from coal, and to obtain data that will allow the performance and economics of a coal biodesulfurization process to be predicted. (VC)

UK PubMed Central (United Kingdom)

BackgroundModeling of a complex biological process can explain the results of experimental studies and help predict its characteristics. Among such processes is transcription in...Full Text Available

UK PubMed Central (United Kingdom)

Despite the availability of dozens of animal genome sequences, two key questions remain unanswered: First, what fraction of any species' genome confers biological function, and second, are apparent...Full Text Available

International Nuclear Information System (INIS)

Rats were exposed to aerosols of "2"3"3U and "2"3"2U nitrate in a study of the long-term biological effects. Preliminary radiation dose estimates show lung > skeleton > kidney in each dose group.

UK PubMed Central (United Kingdom)

Endogenous circadian clocks are robust regulators of physiology and behavior. Synchronization or entrainment of biological clocks to environmental time is adaptive and important for physiological homeostasis...Full Text Available

UK PubMed Central (United Kingdom)

Large population sizes, rapid growth and 3.8 billion years of evolution firmly establish microorganisms as a major source of the planet's biological and genetic diversity. However, up to 99% of the...Full Text Available

UK PubMed Central (United Kingdom)

One selection pressure shaping sequence evolution is the requirement that a protein fold with sufficient stability to perform its biological functions. We present...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveTo evaluate the effect of different concomitant disease modifying antirheumatic drugs (DMARDs) on the persistence with antitumour necrosis factor (anti-TNF) therapies in...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The biological accumulation of heavy metals and cesium, strontium, and uranium in plants is discussed. The role of nutrient deficiencies and foliar treatments of manganese and iron compounds is described.

Science.gov (United States)

... 154. By way of comparison, the aquatic weed Hygrophila polysperma (Roxb.) T. Anderson, a potential target for biological ... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemon...

UK PubMed Central (United Kingdom)

The content of guanine+cytosine varies markedly along the chromosomes of homeotherms and great effort has been devoted to studying this heterogeneity and its biological implications. Already...Full Text Available

UK PubMed Central (United Kingdom)

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

UK PubMed Central (United Kingdom)

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in...Full Text Available

UK PubMed Central (United Kingdom)

Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which...Full Text Available

UK PubMed Central (United Kingdom)

Experimental techniques are presented that can be used to assay and correct for differential light scattering effects in circular dichroism spectra of biological macrostructures. The assay is based...Full Text Available

UK PubMed Central (United Kingdom)

DNA double-strand breaks (DSBs) are generally accepted to be the most biologically significant lesion by which ionizing radiation causes cancer and hereditary disease. However, no information on the...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIt has been assumed that the unusual tail club of ankylosaurid dinosaurs was used actively as a weapon, but the biological feasibility of this behaviour has not been examined...Full Text Available

UK PubMed Central (United Kingdom)

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available

UK PubMed Central (United Kingdom)

A conference entitled ‘2nd International Berlin Bat Meeting: Bat Biology and Infectious Diseases’ was held between the 19 and 21 of February 2010 in Berlin, Germany. Researchers from...Full Text Available

UK PubMed Central (United Kingdom)

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages....Full Text Available

UK PubMed Central (United Kingdom)

The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs...Full Text Available

UK PubMed Central (United Kingdom)

The protein databank (PDB) contains high quality structural data for computational structural biology investigations. We have earlier described a fast tool (the decomp_pdb tool) for identifying and...Full Text Available

International Nuclear Information System (INIS)

The biological and radiobiological peculiarities of seeds and seedlings of the Rumex confertus and Lupinus polycolor plants, which grown during several generations in plots with different level of radionuclide pollution of the Chernobyl exclusive zone have been investigated.

UK PubMed Central (United Kingdom)

Enolase is a multifunctional enzyme that plays important roles in many biological and disease processes. α-Enolase from human liver (hENO1) was expressed as a soluble protein and purified by...Full Text Available

UK PubMed Central (United Kingdom)

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMost rapidly evolving gene families are involved in immune responses and reproduction, two biological functions which have been assigned to the carcinoembryonic antigen...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Radiotherapy with high-energy carbon ion beams can be more advantageous compared to photons because of better physical dose distribution and higher biological efficiency in tumour cell sterilization. Despite enhanced normal tissue sparing, damage incurred by normal cells at the beam entrance is unavoidable and may affect the progeny of surviving cells in the form of inheritable cytogenetic alterations. Furthermore, the quality of the beam along the Bragg curve is modified by nuclear fragmentation of projectile and target nuclei in the body. We present an experimental approach based on the use of a polymethylmethacrylate (PMMA) phantom that allows the simultaneous exposure to a particle beam of several biological samples positioned at various depths along the beam path. The device was used to measure the biological effectiveness of a 60 MeV/amu carbon-ion beam at inducing chromosomal aberrations in G{sub 0}-human peripheral ...

Energy Technology Data Exchange (ETDEWEB)

Initial results obtained with a Monte Carlo computer program designed to link initial physical events in irradiated liquid water with subsequent chemical and biological events are presented. 10 refs., 4 figs., 3 tabs.