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Sample records for 1,2-dihydroxyanthraquinone

  1. Radiosensitization of thymine by Fe(III)-1,2 dihydroxyanthraquinone complex in dilute aqueous solution

    A complex of Fe(III) with 1,2 dihydroxy 9, 10, anthraquinone (DHA) has been prepared. The metal ion forms a 1:3 complex with DHA. The complex is formed due to the dissociation of one proton per ligand bound to the metal ion. The stability constant of the Fe(III) complex is 1.61 x 1032. The complex reduces the catalytic flow of electrons from NADH to molecular O2 through NADH dehydrogenease over DHA. The Fe(III) complex is seen to be an efficient radiosensitizer towards γ-radiation induced degradation of thymine in a nitrous oxide saturated medium. (author). 31 refs., 2 figs., 1 tab

  2. Regularities of distribution of scandium and thorium complexes with alizarin derivatives in aqua-organic systems

    Complexing of thorium and scandium with alizarin derivatives was studied in aqua-acetone media. It was shown that maximal yield of complexes achieved when ph value was 2.5-6.0. Complex composition, stability constants and molar light absorption coefficients were determined by spectrophotometric method. Scandium and thorium were extracted quantitatively from acetate-buffer solutions in the presence of perchlorate or trichloroacetate ions. Complexes were extracted in organic phase with mole ratio R:Me=2:1. Structure of extracted complexes was established on IR and PMR spectra. The 1,2-dihydroxyanthraquinone was the most effective extractant for thorium and scandium ions

  3. Characterisation of novel pH indicator of natural dye Oldenlandia umbellata L.

    Ramamoorthy, Siva; Mudgal, Gaurav; Rajesh, D; Nawaz Khan, F; Vijayakumar, V; Rajasekaran, C

    2009-01-01

    Oldenlandia umbellata L., commonly known as 'chay root', belongs to the family Rubiaceae and is one of the unexplored dye-yielding plants. The roots from this plant are the sources of red dye. Extraction protocol and dye characterisation have not been completely studied so far in this plant. Hence, in this article we have used UV spectrophotometry, thin layer chromatography, GC-MS, high-performance liquid chromatography and NMR to identify the five major colouring compounds, including 1,2,3-trimethoxyanthraquinone, 1,3-dimethoxy-2-hydroxyanthraquinone, 1,2-dimethoxyanthraquinone, 1-methoxy-2-hydroxyanthraquinone and 1,2-dihydroxyanthraquinone. It showed application feasibility as a new pH indicator. PMID:19731140

  4. Assessment of the toxicity of anthracene photo-modification products using the topminnow (Poeciliopsis lucida) hepatoma cell line (PLHC-1)

    Many polycyclic aromatic hydrocarbons (PAHs) are acutely toxic to fish and other aquatic organisms in the presence of environmentally realistic intensities of solar ultraviolet radiation (SUVR). In this study, the cytoxicity/phototoxicity of anthracene photo-modified products to aquatic animals was assessed based on in vitro toxicity assays using a fish hepatoma cell line (PLHC-1 cell line). The results from this study showed that pre-exposure of anthracene/cell culture media to SUVR caused a significant amount of photo-modification and reduced the phototoxicity of parent anthracene compound. SUVR pre-exposed anthracene did not induce cytotoxicity in the absence of SUVR. It was shown that in comparison with anthracene, two major anthracene photo-modified products (anthraquinone, 1,2-dihydroxyanthraquinone) were significantly less phototoxic to PLHC-1 cells. Also in the absence of SUVR, these chemicals did not induce any detectable cytotoxicity to PLHC-1 cells. In conclusion, this study demonstrated that photo-modification reduced the phototoxicity of anthracene to PLHC-1 cells because major anthracene photo-modified products are not phototoxic. Also it was found that these photo-modified anthracene products were not cytotoxic in the absence of SUVR. This study indicated the need for separate toxicity assessments of individual photo-modified PAH products in both animal and plant models