KoreaScience (Korea)

Full Text Available

Science.gov (United States)

Acute Wounds

Science.gov (United States)

In 18 piglets, weighing 10-15 kg, third-degree burns or full-thickness skin excisions of 4 X 4 cm were inflicted. The effect of five dressing materials on adhesiveness to the wounds, appearance, conformability, wound contraction, bacterial count, and morphology of the wound was studied at the end of the seventh and fourteenth days without dressing changes. In 11 piglets with a burn wound, the most adherent dressing was collagen sponge(CS), followed by polyurethane sponge (PU), pigskin xenograph (PS), and xeroform. CS more effectively debrided the wound from coagulated necrotic tissue than the other dressings. Wound contraction was maximal with CS dressing (52%), followed by PU (44%), xeroform (32%), and PS (27%). In another seven piglets with full-thickness excised wounds, a velour dressing made of polytetrafluoroethylene (PTFE) or PU adhered significantly more ...

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to observe both the clinical signs and symptoms of wounds at risk of infection, that is critically colonised (biofilm infected) and antimicrobial-performance of an ionic silver alginate/carboxymethylcellulose (SACMC) dressing, in comparison with a non silver calcium alginate fibre (AF) dressing, on chronic venous leg and pressure ulcers. Thirty-six patients with venous or pressure ulcers, considered clinically to be critically colonised (biofilm infected), were randomly chosen to receive either an SACMC dressing or a non silver calcium AF dressing. The efficacy of each wound dressing was evaluated over a 4-week period. The primary study endpoints were prevention of infection and progression to wound healing. The SACMC group showed a statistically significant (P = ...

UK PubMed Central (United Kingdom)

AbstractThree biologic dressings [split-thickness allogeneic skin (STS)], allogeneic peritoneum (P), and xenogenic porcine small intestinal submucosa (PSIS)] were...Full Text Available

Science.gov (United States)

The main objective of Phase I of this SBIR project was to demonstrate the feasibility for successful development of an antimicrobial wound dressing based on a hydrogel sustained release matrix. This goal has been achieved. In vitro studies of drug diffusi...

British Library Electronic Table of Contents (United Kingdom)

Abstract Silver-impregnated wound dressings continue to be routinely used for the management of infected wounds, or wounds that are at risk of becoming infected. The ability of antimicrobials that have been incorporated into wound dressings to kill microorganisms within the dressing requires appropriate evaluation using in vitro models. In vitro models that have been exploited for this purpose have included the corrected zone of inhibition and the log reduction assay. However, these and other related culturable-based assays are purported to have poor correlation with the overall microbicidal barrier activity of an antimicrobial wound dressing. This is because culturable-based methods only retrospectively indicate bacterial cell death and do not take into account viable but nonculturable st...

Science.gov (United States)

There is a plethora of new silver-containing dressings on the market today. Various manufacturers attempt to show that their dressings are the most efficacious and therefore should be preferentially employed by health care workers based on the results of their in vitro tests. However, there have been no studies that clearly identify which tests are appropriate for comparison purposes. The purpose of this study was to determine which in vitro test is most appropriate for evaluating the antimicrobial efficacy of silver-containing dressings. This was done by testing seven silver-containing dressings and two non-silver-containing topical agents against 17 clinically relevant microorganisms using zone of inhibition assays and time-kill kinetic assays in complex media. The results for the two assays were then correlated to determine whether the methods generated similar results. It was determined that the two ...

British Library Electronic Table of Contents (United Kingdom)

Greenman J, Thorn RMS, Saad S, Austin AJ. In vitro diffusion bed, 3-day repeat challenge `capacity' test for antimicrobial wound dressings. Int Wound J 2006;3:322-329. Abstract The aim of this study was to develop an in vitro wound infection model that allows the comparison of the bacterial kill rate of antimicrobial wound dressings over the course of 3 days, with renewed microbial challenges each day, under realistic wound-like conditions. A test bed model of a moderately exuding wound was constructed from a hydrogel containing releasable foetal calf serum (FCS), and cellulose discs dosed with test microbes (Methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa) suspended in 50% FCS applied at the interface between the test dressing and the hydrogel test bed. Freshly prep...

Energy Technology Data Exchange (ETDEWEB)

A decontamination washer for working dresses using liquid and supercritical carbon dioxide were designed and manufactured. The size of reactor for decontamination and solidification is about 16 liter. The system is a closed one with recycling ability of carbon dioxide. The efficiency of recycling of carbon dioxide and that of separation of solutes in carbon dioxide were checked. They met all the design goals. A remote control system of the carbon dioxide flow was set in a control panel. The manufactured decontamination washer was brought to Wolsung nuclear power plants, and installed to check the efficiency of decontamination and the feasibility of usage in nuclear power plants. The elimination of radioactive oil from the contaminated dresses were very high. However, the decontamination factor was lower than the design goal value. It's due to the low removal rate of radioactive particles attached on the dresses.

International Nuclear Information System (INIS)

We show how the formulation of the matrix models as conformal field theories on a Riemann surfaces can be used to compute the genus expansion of the observables. Here we consider the simplest example of the Hermitian matrix model, where the classical solution is described by a hyperelliptic Riemann surface. To each branch point of the Riemann surface we associate an operator which represents a twist field dressed by the modes of the twisted boson. The partition function of the matrix model is computed as a correlation function of such dressed twist fields. The perturbative construction of the dressing operators yields a set of Feynman rules for the genus expansion, which involve vertices, propagators and tadpoles. The vertices are universal, the propagators and the tadpoles depend on the Riemann surface. As a demonstration we evaluate the genus-two free energy using the Feynman rules.

British Library Electronic Table of Contents (United Kingdom)

Abuzakuk T, Coward P, Shenava Y, Kumar VS, Skinner JA. The management of wounds following primary lower limb arthroplasty: a prospective, randomised study comparing hydrofibre and central pad dressings. Abstract Wound care following lower limb arthroplasty has not been subject to in-depth clinical research, primarily because such wounds usually heal without complication. However, when prosthetic implants are used, serious wound problems can be disastrous (Whitehouse et al. Infect Control Hosp Epidemiol 2002;23:183-9; Lindwell OM. Clin Orthop Relat Res 1986;211:91-103). We report the results of a prospective, randomised, controlled trial comparing a hydrofibre (Aquacel) and central pad (Mepore) dressing in the management of acute wounds following primary total hip or knee arthroplasty left ...

British Library Electronic Table of Contents (United Kingdom)

Polyurethane (PU) foam was combined with protein drug-loaded pH-sensitive alginate-bentonite hydrogel for wound dressings. Alginate is a linear copolymer composed of 1?4-linked ?-D-mannuronic acid (M) and its c-5-epimer ?-Lguluronic acid (G). The amount of (M) and (G) and their sequential distribution are varied depending on the alginate source. Soluble sodium alginate can become a hydrogel when cross-linked with divalent cations and has widespread applications in the food, drink, pharmaceutical and bioengineering industries. Recently, it has been also proposed as a biomaterial for drug delivery systems. Bentonites are the natural inorganic polymers consisting of a large proportion of expandable clay minerals with a three-layer structure such as montmorillonite, beidellite, nontronite, etc...

CERN Document Server

We analyze the driven resonantly coupled Jaynes-Cummings model in terms of a quasienergy approach by switching to a frame rotating with the external modulation frequency and by using the dressed atom picture. A quasienergy surface in phase space emerges whose level spacing is governed by a rescaled effective Planck constant. Moreover, the well-known multiphoton transitions can be reinterpreted as resonant tunneling transitions from the local maximum of the quasienergy surface. Most importantly, the driving defines a quasienergy well which is nonperturbative in nature. The quantum mechanical quasienergy state localized at its bottom is squeezed. In the Purcell limited regime, the potential well is metastable and the effective local temperature close to its minimum is uniquely determined by the squeezing factor. The activation occurs in this case via dressed spin flip transitions rather than via quantum activation as in other driven nonlinear ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Objective: The aim of this investigation was to compare the healing of laser-irradiated and non-irradiated wounds covered by an occlusive dressing in mice. Background data: Many previous studies of the effects of laser irradiation of experimental wounds in mice and rats did not cover the wounds so that healing occurred mainly by contraction. Healing of covered wounds is slower and mimics more closely wound healing in humans. Materials and Methods: Forty-seven diabetic and twenty non-diabetic mice were used. A single wound (5?mm diameter) was created on the left flank of each animal and covered by Tegaderm HP dressing (Day 1). Wounds were irradiated (660?nm) for 20?s using a lower power (18?mW) or higher power (80?mW) laser starting immediately post-wounding for seven consecutive d...

British Library Electronic Table of Contents (United Kingdom)

New nanofibers containing poly(vinyl pyrrolidone)-iodine complex (PVP-iodine) were obtained by electrospinning in order to prepare materials suitable for wound dressings. Different approaches were used: a one-step method based on electrospinning of PVP-iodine or poly(ethylene oxide)/PVP-iodine solutions and a three-step method based on electrospinning of PVP or poly(ethylene oxide)/PVP mixed solutions followed by photo-mediated crosslinking of the obtained nanofibers and subsequent complexation with iodine. The average diameters of the fibers were in the range 150-470nm depending on the composition and on the applied field strength (AFS) and increased with increasing the amount of PEO in the spinning solutions. Higher AFS resulted in greater fiber diameter and in size distribution broadeni...

International Nuclear Information System (INIS)

The action of the Virasoro algebra on integrable hierarchies of non-linear equations and on related objects ('Schroedinger' differential operators) is investigated. The method consists in pushing forward the Virasoro action to the wave function of a hierarchy, and then reconstructing its action on the dressing and Lax operators. This formulation allows one to observe a number of suggestive similarities between the structures involved in the description of the Virasoro algebra on the hierarchies and the structure of conformal field theory on the world-sheet. This includes, in particular, an 'off-shell' hierarchy version of operator products and of the Cauchy kernel. In relation to matrix models, which have been observed to be effectively described by integrable hierarchies subjected to Virasoro constraints, I propose to define general Virasoro-constrained hierarchies also in terms of dressing operators, by certain equations which carry the ...

Science.gov (United States)

This issue of Exploratorium Magazine focuses on Antarctica. Antarctica has one of the most extreme climates in the world with an untouched environment inviting researchers with great opportunities for study. This issue describes the journey of four Exploratorium staff members to frozen Antarctica. Chapters include: (1) "Life at the Bottom of the World"; (2) "Try This! Dress the Scientist"; (3) "South Pole Astronomy"; and (4) "Ground Truth." (YDS)

British Library Electronic Table of Contents (United Kingdom)

Abuzakuk T, Coward P, Shenava Y, Kumar VS, Skinner JA. The management of wounds following primary lower limb arthroplasty: a prospective, randomised study comparing hydrofibre and central pad dressings. Pris en charge des plaies apres arthroplastie primaire du member inferieur: une etude randomisee prospective comparant hydrofibre et pansements central pad La prise en charge des plaies apres arthroplastie du member inferieur n'a pas fait l'objet de recherches approfondies, essentiellement car ces plaies cicatrisent habituellement sans complications. Cependant, lorsque des implants prothetiques sont utilizes, les serieux problemes de plaies peuvent devenir desastreux. Nous rapportons les resultants d'une etude prospective, randomisee, controlee comparant un hydrofibre et un pasnement centra...

Energy Technology Data Exchange (ETDEWEB)

We duscuss a resonant microwave trap for neutral atoms. Because of the long spontaneous radiation time this trap is remarkably different from the optical trap. It also has advantages over static magnetic traps that trap the excited spin state of the lowest electronic level, in that atoms predominantly in the spin ground state can be trapped. We analyze the relaxation-ejection lifetime of atoms in such a trap using the formalism of dressed atomic states. Results are appliedi to atomic hydrogen and the possibility of Bose-Einstein condensation is considered.

Science.gov (United States)

We present a Poincare covariant Faddeev equation, which enables the simultaneous prediction of meson and baryon observables using the leading order in a truncation of the Dyson-Schwinger equations that can systematically be improved. The solution describes a nucleon's dressed-quark core. The evolution of the nucleon mass with current-quark mass is discussed. A nucleon-photon current, which can produce nucleon form factors with realistic Q{sup 2} evolution, is described. Axial-vector diquark correlations lead to a neutron Dirac form factor that is negative, with r{sub 1}{sup nu}>r{sub 1}{sup nd}. The proton electric-magnetic form factor ratio falls with increasing Q{sup 2}.

British Library Electronic Table of Contents (United Kingdom)

Within the framework of the effective-mass approximation, using a variational method, we have calculated the effect of intense laser radiation on the binding energy of the shallow-donor impurities in a Ga1- x In x N y As1- y /GaAs single quantum well for different nitrogen and indium mole concentrations. Our numerical results show that the binding energy strongly depends on the laser intensity and frequency (via the laser dressing parameter) and it also depends on the nitrogen and indium concentrations. Impurity binding energy under intense laser fields can be tuned by changing the nitrogen and indium mole fraction.

Science.gov (United States)

Recently, various types of allogeneic skin substitutes including cultured epidermal substitute (CES), cultured dermal substitute (CDS), and cultured skin substitute (CSS), which are composed of keratinocytes and/or fibroblasts as the cellular component(s), have been used as biological wound dressings. In our study, the allogeneic CDS was prepared by plating fibroblasts on a spongy collagen. The clinical evaluation was conducted using fresh or cryopreserved allogeneic CDS. In 145 of our clinical cases, 95% (138/145) of various wounds were evaluated as achieving good or excellent results, including 96% (22/23) of deep dermal burns (DDB) and dermal burns (DB), 100% (53/53) of partial-thickness donor wounds, 91% (21/23) of traumatic skin defects, 100% (5/5) of pressure ulcers, 82% (9/11) of chronic skin ulcers, 100% (6/6) of coverage for debrided DB, and 92% (22/24) of coverage for autologous meshed graft. The results obtained in our study suggest that the allogeneic ...

Energy Technology Data Exchange (ETDEWEB)

Soil dressing on coal ash reclaimed land is a covering to use the land for agriculture. This study was carried out to find out the necessary depth of soil covering the ash layer in order to have normal crop growth. Two kinds of crops, Japanese radish, and rakkyo were planted in cover soil on the fly ash packed in wooden boxe (90 cm x 90 cm x 90 cm). Depths of cover soil were 20 cm, 30 cm, 40 cm and 50 cm. The results were summarized as follows: growth and yield of Japanese radish and rakkyo were increased with increasing depth of cover soil; root development of Japanese radish was inhibited at the lower coal ash layer. Main root length and edible root length of Japanese radish were decreased with decreasing depth of cover soil; boron and molybdenum contents in the plants remarkably increased with decreasing depth of cover soil. This may be due to the absorption of these elements from fly ash layer; it is concluded that optimum depth of cover soil should be more ...

International Nuclear Information System (INIS)

The difference of NH_4"+-N/NO_3"--N nutrition between hybrid and conventional rice varieties at the late growth stage was studied by using "1"5N-tracer technique. The results showed that the nitrate fertilizer utilization efficiency by the hybrid rice after anthesis was 7.8% higher than that by the ordinary rice variety, and the nitrate fertilizer recovery fraction by the former was 13.2% greater than that by the latter. The varietal difference in NO_3"--N uptake and utilization was almost twice as that in NH_4"+-N. It was also showed that "1"5N distribution in ear of the hybrid rice was about 20% greater than that of the conventional variety, but there were no obvious differences between NO_3"--N and NH_4"+-N. However, "1"5N distribution in the lower node leaves and root was found to be significant higher with NO_3"--N than that with NH_4"+-N in both rice varieties, particularly in the hybrid rice. Compared with NH_4"+-N, NO_3"--N top-dressing before anthesis was ...

International Nuclear Information System (INIS)

In order to investigate the systematics of the loop expansion in high temperature gauge theories beyond the leading order hard thermal loop (HTL) approximation, we calculate the two-loop electron proper self-energy #SIGMA# in high temperature QED. The two-loop bubble diagram of #SIGMA# contains a linear infrared divergence. Even if regulated with a nonzero photon mass M of order of the Debye mass, this infrared sensitivity implies that the two-loop self-energy contributes terms to the fermion dispersion relation that are comparable to or even larger than the next-to-leading order (NLO) contributions of the one-loop #SIGMA#. Additional evidence for the necessity of a systematic restructuring of the loop expansion comes from the explicit gauge-parameter dependence of the fermion damping rate at both one and two loops. The leading terms in the high temperature expansion of the two-loop self-energy for all topologies arise from an explicit hard-soft factorization pattern, in which one of ...

Energy Technology Data Exchange (ETDEWEB)

Repeated exposure to cold air reduces the metabolic response to cold air exposure in man. The purpose of this investigation was to measure the change in resting metabolic rate (RMR) with exposure to 22C air and 4C air during a 12 day period. Four women sat in 22C air for 45 min followed by 45 min in 4C air each day for ten days. The authors measured RMR during a 45 min period in 22C air followed by 45 min in 4C air on four days. All subjects began their morning exposures on a Monday within 2 days of the onset of menses completing the study on a Friday, 12 days later. Subjects dressed in a T-shirt, shorts and cotton socks. During 45 min of exposure to warm air, RMR remained steady at 10% of VO{sub 2peak} on Day 1 and 10% on Day 5. RMR during exposure to warm air significantly increased to 13% of VO{sub 2peak} on Day 8 and remained elevated at 13% on Day 12. During exposure to cold air RMR peaked at 31% of CO{sub 2peak} by the 5th min on Day 1. Peak RMR on Day 5 was ...