Sample records for 01llb k58 h21

  1. Preparation of a Lipopolysaccharide from Escherichia coli 01lla, 01llb, k58: h21 bacterial wall, labeled with carbon-14

    A brief description of the morphological and chemical structure of Li po polysaccharides is given, as well as its occurrence in nature and its mechanisms of action. It is emphasized the usefulness for actual biochemical and biomedical research of the labeled Lipopolysaccharide. The method for the labelling, isolation and purification of 14''C-Lipopolysacchari de is described. (Author) 23 refs

  2. Preparation of a Lipopolysaccharide from Escherichia coli 01lla, 01llb, k58: h21 bacterial wall, labeled with carbon-14; Preparacion de un lipopolisacarido de la pared baceteriana de escherichia coli 01lla, 01llb, K58: H21, marcado con carbono-14

    Solano Aunon, M. L.; Pacheco Lopez, J.; Garcia Pineda, M. D.; Roca, M.; Bayon, A.


    A brief description of the morphological and chemical structure of Li po polysaccharides is given, as well as its occurrence in nature and its mechanisms of action. It is emphasized the usefulness for actual biochemical and biomedical research of the labeled Lipopolysaccharide. The method for the labelling, isolation and purification of 14''C-Lipopolysacchari de is described. (Author) 23 refs.

  3. Fluorescence Quenching of Anthracene by N,N-Diethylaniline and Phenothiazine in Triton X-100/n-C10H21OH/H2O Microemulsion

    GUO Xia; XU Hui; GUO Rong


    The photo-induced electron transfer reactions of anthracene with N,N-diethylaniline(DEA) and phenothiazine(PTZ) occur in the membrane phase of a Triton X-100/n-C10H21OH(1-decanol)/H2O microemulsion. DEA and PTZ exist in the membrane phase of the microemulsion. Anthracene exists in the oil continuous phase of the W/O microemulsion and in the oil core and membrane phase of the O/W microemulsion.

  4. Radioimmunoscintigraphy of colorectal carcinoma using technetium-99m-labeled, totally human monoclonal antibody 88BV59H21-2.

    Gulec, S A; Serafini, A N; Moffat, F L; Vargas-Cuba, R D; Sfakianakis, G N; Franceschi, D; Crichton, V Z; Subramanian, R; Klein, J L; De Jager, R L


    Radioimmunoscintigraphy (RIS) using human monoclonal antibodies offers the important clinical advantage of repeated imaging over murine monoclonal antibodies by eliminating the cross-species antibody response. This article reports a Phase I-II clinical trial with Tc-99m-labeled, totally human monoclonal antibody 88BV59H21-2 in patients with colorectal carcinoma. The study population consisted of 34 patients with colorectal cancer (20 men and 14 women; age range, 44-81 years). Patients were administered 5-10 mg antibody labeled with 21-41 mCi Tc-99m by the i.v. route and imaged at 3-10 and 16-24 h after infusion using planar and single-photon emission computed tomographic (CT) techniques. Pathological confirmation was obtained in 25 patients who underwent surgery. Human antihuman antibody (HAHA) titers were checked prior to and 1 and 3 months after the infusion. RIS with Tc-99m-labeled 88BV59H21-2 revealed a better detection rate in the abdomen-pelvis region compared with axial CT. The combined use of both modalities increased the sensitivity in both the liver and abdomen-pelvis regions. Ten patients developed mild adverse reactions (chills and fever). No HAHA response was detected in this series. Tc-99m-labeled human monoclonal antibody 88BV59H21-2 RIS shows promise as a useful diagnostic modality in patients with colorectal cancer. RIS alone or in combination with CT is more sensitive than CT in detecting tumor within the abdomen and pelvis. Repeated RIS studies may be possible, due to the lack of a HAHA response. PMID:7493345

  5. Solvothermal indium fluoride chemistry: Syntheses and crystal structures of K 5In 3F 14, β-(NH 4) 3InF 6 and [NH 4] 3[C 6H 21N 4] 2[In 4F 21

    Jayasundera, Anil C. A.; Goff, Richard J.; Li, Yang; Finch, Adrian A.; Lightfoot, Philip


    The solvothermal syntheses and crystal structures of three indium fluorides are presented. K 5In 3F 14 ( 1) and β-(NH 4) 3InF 6 ( 2) are variants on known inorganic structure types chiolite and cryolite, respectively, with the latter exhibiting a complex and apparently novel structural distortion. [NH 4] 3[C 6H 21N 4] 2[In 4F 21] ( 3) represents a new hybrid composition displaying a unique trimeric metal fluoride building unit.

  6. Emergence of clonal groups O1:HNM-D-ST59; O15:H1-D-ST393; O20:H34/HNM-D-ST354; O25b:H4-B2-ST131 and ONT:H21,42-B1-ST101 among CTX-M-14-producing clinical isolates in Galicia; northwest Spain

    Mora, Azucena; Blanco, Miguel; López, Cecilia; Mamani, Rosalia; Blanco, Jesús E.; Alonso, María Pilar; García-Garrote, Fernando; Dahbi, Ghizlane; Herrera, Alexandra; Fernández, Ana; Fernández, Begoña; Agulla, Andrés; Bou, Germán; Blanco, Jorge


    Abstract CTX-M enzymes, mainly CTX-M-14 and CTX-M-15, have emerged as the most prevalent extended-spectrum ?-lactamase (ESBL) type produced by Escherichia coli in Spain, with successful dissemination of clonal group O25b:H4-B2-ST131 producing CTX-M-15 within the hospital and community settings. However, until now CTX-M-14-producing E. coli in Spain had been shown to belong to a wide variety of serotypes with no predominance of a certain clonal group. In the present study, 654 E. co...

  7. Dicty_cDB: SSJ827 [Dicty_cDB

    Full Text Available .0 1 CF833901 |CF833901.1 UCRCS02_04H21_r Ruby Orange Ovary at Anthesis cDNA Library Citrus sinensis cDNA CS_REa04H21, mRNA sequence. 74 1e-25 4 CF833900 |CF833900.1 UCRCS02_04H21_f Ruby

  8. Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta(2)-microglobulin

    Heegaard, N.H.H.; Jørgensen, T.J.D.; Rozlosnik, N.;


    . Using amide hydrogen/deuterium exchange monitored by mass spectrometry, we show that Delta K58-beta(2)m has increased unfolding rates compared to wt-beta(2)m and that unfolding is highly temperature dependent. The unfolding rate is I order of magnitude faster in Delta K58-beta(2)M than in wt-beta(2)m...... fluorescence. After a few days at 37 degrees C, in contrast to wt-beta(2)M, Delta K-58-beta(2)M forms well-defined high molecular weight aggregates that are detected by size-exclusion chromatography. Atomic force microscopy after seeding with amyloid-beta(2)m fibrils under conditions that induce minimal...

  9. Dicty_cDB: SSG647 [Dicty_cDB

    Full Text Available 833901.1 UCRCS02_04H21_r Ruby Orange Ovary at Anthesis cDNA Library Citrus sinensis cDNA clone CS_REa04H21, ...mRNA sequence. 74 1e-24 4 CF833900 |CF833900.1 UCRCS02_04H21_f Ruby Orange Ovary at Anthesis cDNA Library Ci

  10. Transformational leadership sub-dimensions and their link to leaders' personality and performance

    A. Deinert; A.C. Homan; D. Boer; S.C. Voelpel; D. Gutermann


    The multi-dimensionality of the transformational leadership construct has been under debate in the last decades. To shed more light on this issue, we conducted a meta-analysis (k = 58 studies), examining the transformational leadership sub-dimensions and their links to leader personality and perform

  11. Genome sequencing and comparative genomics provides insights on the evolutionary dynamics and pathogenic potential of different H-Types of Shiga toxin-producing Escherichia coli O104

    Various Shiga toxin-producing Escherichia coli (STEC) O104 H-types including H4, H7, H21, and H¯ have been associated with sporadic cases of illness and have caused outbreaks globally. In the U.S., STEC O104:H21 caused an outbreak associated with milk in 1994. The aim of this work was to conduct a...

  12. AcEST: DK957104 [AcEST

    Full Text Available TST39A01NGRL0027_H21 577 Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0027_H21. 5' end seq ... ranslation initiation factor 4... 30 6.7 sp|Q9NB31|CST1 _CAEEL Serine/threonine-protein kinase cst-1 OS=Ca. ...

  13. AcEST: DK950375 [AcEST

    Full Text Available TST38A01NGRL0008_H21 703 Adiantum capillus-veneris mRNA. clone: TST38A01NGRL0008_H21. 5' end seq ... KFLRPHYGKLKEIYENMA 114 Query: 385 EGDLKRYLADIISVLALTMS EEGERESLKFRLLGSVEDIGSWGHEYVRNLAGEIGVEFQT 564 G+ KR+ ... ADIISVLA+TMS ... GERE LK+RL+GS E++ SWGHEYVR+LAGE+ E+Q Sbjct: 115 PG ...

  14. Dicty_cDB: SLE886 [Dicty_cDB

    Full Text Available slug cDNA, clone SSG647. 938 0.0 1 ( CF833901 ) UCRCS02_04H21_r Ruby Orange Ovary...( CX643300 ) UCRPT02_67F01_g Poncirus trifoliata Roots with Ir... 64 1e-22 4 ( CF833900 ) UCRCS02_04H21_f Ruby

  15. SwissProt search result: AK069229 [KOME

    Full Text Available AK069229 J023012H21 (O88705) Potassium/sodium hyperpolarization-activated cyclic nu...cleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3) HCN3_MOUSE 4e-16 ...

  16. SwissProt search result: AK069229 [KOME

    Full Text Available AK069229 J023012H21 (Q9TV66) Potassium/sodium hyperpolarization-activated cyclic nu...cleotide-gated channel 4 (Hyperpolarization-activated cation channel 4) (HAC-4) HCN4_RABIT 9e-16 ...

  17. Drug: D02281 [KEGG MEDICUS

    Full Text Available D02281 Drug Levalbuterol hydrochloride (USAN); Xopenex (TN) C13H21NO3. HCl 275.1288 275.7717 D02 ... 281.gif Bronchodilator; Asthma ... prophylactic [DS:H00079] beta2-adrenergic receptor ...

  18. Drug: D08046 [KEGG MEDICUS

    Full Text Available D08046 Drug Hydrocodone hydrochloride; Dihydrocodeinone hydrochloride; Dicodid (TN) C18H21NO3. H ... assification [BR:br08303] R RESPIRATORY SYSTEM R05 COUGH ... AND COLD PREPARATIONS R05D COUGH ... SUPPRESSANTS, EXC ...

  19. Drug: D02100 [KEGG MEDICUS

    Full Text Available D02100 Drug Ziprasidone mesylate (USAN); Ziprasidone mesylate hydrate; Geodon (TN) C21H21ClN4OS. ... cal Ziprasidone D02100 Ziprasidone mesylate (USAN) Bipolar ... Agents Bipolar ... Agents, Other Ziprasidone D02100 Zi ...

  20. Cross-reactivity of major outer membrane proteins of Enterobacteriaceae, studied by crossed immunoelectrophoresis.

    Hofstra, H.; Van Tol, J D; Dankert, J


    Outer membrane fractions were prepared from 11 bacteria in the family Enterobacteriaceae: Escherichia coli serotypes O1K-, O4K2, O26K60, O75K-, and O111K58, Shigella flexneri, Salmonella typhimurium, Klebsiella pneumonia, Serratia marcescens, Proteus vulgaris, Proteus mirabilis, and Providencia stuartii. All strains studied were found to contain one non-peptidoglycan-bound, heat-modifiable outer membrane protein, and one or two peptidoglycan-associated major outer membrane proteins in the 27,...

  1. A novel chalcone derivative attenuates the diabetes-induced renal injury via inhibition of high glucose-mediated inflammatory response and macrophage infiltration

    Fang, Qilu [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China); Zhao, Leping [Department of Pharmacy, the Affiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou, Zhejiang (China); Wang, Yi; Zhang, Yali [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China); Li, Zhaoyu [Department of International High School, Shanghai Jiaotong University Nanyang Affiliated (Kunshan) School, Minhang District, Shanghai (China); Pan, Yong; Kanchana, Karvannan; Wang, Jingying; Tong, Chao [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China); Li, Dan, E-mail: [Department of Nephrology, the Affiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou, Zhejiang (China); Liang, Guang, E-mail: [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China)


    Inflammation plays a central role in the development and progression of diabetic nephropathy (DN). Researches on novel anti-inflammatory agents may offer new opportunities for the treatment of DN. We previously found a chalcone derivative L6H21 could inhibit LPS-induced cytokine release from macrophages. The aim of this study was to investigate whether L6H21 could ameliorate the high glucose-mediated inflammation in NRK-52E cells and attenuate the inflammation-mediated renal injury. According to the results, L6H21 showed a great inhibitory effect on the expression of pro-inflammatory cytokines, cell adhesion molecules, chemokines, and macrophage adhesion via down-regulation of NF-κB/MAPKs activity in high glucose-stimulated renal NRK-52E cells. Further, in vivo oral administration with L6H21 at a dosage of 20 mg/kg/2 days showed a decreased expression of pro-inflammatory cytokines, cell adhesion molecules, which subsequently contributed to the inhibition on renal macrophage infiltration, the reduction of serum creatinine and BUN levels, and the improvement on the fibrosis and pathological changes in the renal tissues of diabetic mice. These findings provided that chalcone derived L6H21 may be a promising anti-inflammatory agent and have the potential in the therapy of diabetic nephropathy, and importantly, MAPK/NF-κB signaling system may be a novel therapeutic target for human DN in the future. - Highlights: • Inflammation plays a central role in the development of diabetic nephropathy. • Compound L6H21 reduced the high glucose-mediated inflammation in NRK-52E cells. • Compound L6H21 attenuated the inflammation-mediated renal injury. • L6H21 exhibited anti-inflammatory effects via inactivation of NF-κB/MAPKs. • MAPKs/NF-κB may be a novel therapeutic target in diabetic nephropathy treatment.

  2. Dicty_cDB: VSF780 [Dicty_cDB

    Full Text Available 0.17 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing seed Prunus dulcis cDNA clone PA__Ea0001H21f, ...mic clone UUGC1M0399K06 R, DNA sequence. 48 0.17 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing

  3. Survival in acidic and alcoholic medium of Shiga toxin-producing Escherichia coli O157:H7 and non-O157:H7 isolated in Argentina

    Sanz Marcelo E


    Full Text Available Abstract Background In spite of Argentina having one of the highest frequencies of haemolytic uraemic syndrome (HUS, the incidence of Escherichia coli O157:H7 is low in comparison to rates registered in the US. Isolation of several non-O157 shiga toxin-producing Escherichia coli (STEC strains from cattle and foods suggests that E. coli O157:H7 is an uncommon serotype in Argentina. The present study was undertaken to compare the survival rates of selected non-O157 STEC strains under acidic and alcoholic stress conditions, using an E. coli O157:H7 strain as reference. Results Growth at 37°C of E. coli O26:H11, O88:H21, O91:H21, O111:H-, O113:H21, O116:H21, O117:H7, O157:H7, O171:H2 and OX3:H21, was found to occur at pH higher than 4.0. When the strains were challenged to acid tolerance at pH as low as 2.5, viability extended beyond 8 h, but none of the bacteria, except E. coli O91:H21, could survive longer than 24 h, the autochthonous E. coli O91:H21 being the more resistant serotype. No survival was found after 24 h in Luria Bertani broth supplemented with 12% ethanol, but all these serotypes were shown to be very resistant to 6% ethanol. E. coli O91:H21 showed the highest resistance among serotypes tested. Conclusions This information is relevant in food industry, which strongly relies on the acid or alcoholic conditions to inactivate pathogens. This study revealed that stress resistance of some STEC serotypes isolated in Argentina is higher than that for E. coli O157:H7.

  4. AcEST: DK957413 [AcEST

    Full Text Available tr|Q87H21|Q87H21_VIBPA Putative uncharacterized protein VPA1144 ... 36 0.84 tr|A6AZ58|A6AZ58_VIBPA CytoChrome...DE 188 Query: 120 SLDWTLRE 97 SLDW + E Sbjct: 189 SLDWMIEE 196 >tr|A6AZ58|A6AZ58_VIBPA CytoChrome c subfamil

  5. A performance assessment of source correlation and weathering indices for petroleum hydrocarbons in the environment

    The source of petroleum contaminants in the environment and the extent to which these contaminants have weathered following deposition can often be determined through an empirical evaluation of oil n-alkanes, isoprenoids (pristane and phytane), and hopane and sterane biomarkers. Common source correlation and weathering indices have been calculated for three sets of oil samples: fresh, 25% (w/w) weathered, and 50% (w/w) physically weathered diesel standards, crude oils from different sources, and a set of representative heavy oils. For the weathered diesel oils, the C18:phytane demonstrated low specificity between the oils. C18:17α(H),21β(H)-Hopane and n-alkanes:17α(H),21β(H)-hopane differentiated between crude oils but would be expected to vary significantly during weathering due to the microbial amenability of the alkane numerators. Pristane:phytane, phytane:17α,21β-hopane and tricyclic terpanes:hopanes were considered to be the indices best able to distinguish between oils from different origins, based on these results. 17α(H),21β(H)-Hopane:17α(H),21β(H)-norhopane did not adequately distinguish between the respective crude oil samples. Finally, the relationship between heavy oil composition and the index value was investigated. Here, the values of n-alkanes:17α(H),21β(H)-hopane, phytane:17α(H),21β(H)-hopane, and tricyclic terpanes:hopanes decreased as the combined total of polar and asphaltene compounds within oil samples increased. This relationship may be useful in assessing the degradation status of petroleum wastes

  6. Synthesis and use of radio cobaltic EDTA as an extracellular marker in rabbit heart

    Bridge, John H. B.; Bersohn, Malcolm M.; Gonzalez, Frank; BASSINGTHWAIGHTE, JAMES B.


    A new γ-labeled marker for extracellular space is the cobaltic form of 58Co-ethylenediaminetetraacetic acid (58Co-EDTA). The cobaltic ion has a much higher affinity for EDTA than the cobaltous ion; it is prepared as a potassium salt, K+(58Co3+-EDTA4−), and is apparently biologically inert. Testing by equilibration in intact rabbits and comparing the myocardial content with that of [14C]sucrose give values of the volume of distribution in the myocardium of 0.294 ± 0.052 ml/g for 58Co-EDTA and ...

  7. AcEST: DK952954 [AcEST


  8. Di-μ-thio­cyanato-bis­[bis­(tri-p-tolyl­phosphine)silver(I)] 0.35-hydrate

    Khumalo, Nozipho M.; Meijboom, Reinout; Muller, Alfred; Omondi, Bernard


    In the binuclear centrosymmetric title compound, [Ag2(NCS)2(C21H21P)4]·0.35H2O, a pseudo-polymorph of [Ag2(NCS)2(C21H21P)4]·2CH3CN, the Ag atom is coordinated by two phosphine ligands and two bridging thio­cyanate ligands in a distorted tetra­hedral configuration. The crystal structure exhibits inter­molecular C—H⋯π inter­actions.

  9. Drug: D08043 [KEGG MEDICUS

    Full Text Available D08043 Drug Hyaluronic acid (BAN); Captique (TN) (C14H21NO12)n D08043.gif Antirheumatoid; Dermat ... SENSORY ORGANS S01 OPHTHALMOLOGICALS S01K SURGICAL AIDS ... S01KA Viscoelastic substances S01KA01 Hyaluronic a ...

  10. Dichlorido(η6-toluene[tris(4-methoxyphenylphosphine]ruthenium(II

    Rui-Xiang Li


    Full Text Available In the title compound, [RuCl2(C7H8(C21H21O3P], the RuII atom possesses a pseudo-octahedral geometry and the metrical parameters around the metallic core compare well with those of similar three-legged-piano-stool complexes.

  11. 27 CFR 21.49 - Formula No. 23-H.


    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Formula No. 23-H. 21.49 Section 21.49 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... and Authorized Uses § 21.49 Formula No. 23-H. (a) Formula. To every 100 gallons of alcohol add:...

  12. Deacetyl tenuazonic acid p-toluenesulfonylhydrazone

    Irene Nehls


    Full Text Available The title compound {systematic name: 4-methyl-N′-[(3E-2-(1-methylpropyl-5-oxopyrrolidin-3-ylidene]benzenesulfonohydrazide}, C15H21N3O3S, is the condensation product of deacetyl tenuazonic acid (DTA and p-toluenesulfonohydrazide. The crystal structure consists of chains along [100] linked by N—H...O hydrogen bonds.

  13. Drug: D07345 [KEGG MEDICUS

    Full Text Available D07345 Drug Fipexide (INN) C20H21ClN2O4 388.119 388.8447 D07345.gif ATC code: N06BX05 Anatomical ... OANALEPTICS N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD ... AND NOOTROPICS N06BX Other psychostimulants and no ...

  14. Drug: D08280 [KEGG MEDICUS

    Full Text Available D08280 Drug Nizofenone (INN) C21H21ClN4O3 412.1302 412.8694 D08280.gif Nootropic; Vasodilator,ce ... OANALEPTICS N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD ... AND NOOTROPICS N06BX Other psychostimulants and no ...

  15. Drug: D04741 [KEGG MEDICUS

    Full Text Available D04741 Drug Linopirdine (USAN/INN) C26H21N3O 391.1685 391.4644 D04741.gif Alzheimer's disease tr ... OANALEPTICS N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD ... AND NOOTROPICS N06BX Other psychostimulants and no ...

  16. Drug: D07343 [KEGG MEDICUS

    Full Text Available D07343 Drug Fencamfamin (INN) C15H21N 215.1674 215.3339 D07343.gif ATC code: N06BA06 Anatomical ... OANALEPTICS N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD ... AND NOOTROPICS N06BA Centrally acting sympathomime ...

  17. Drug: D01465 [KEGG MEDICUS

    Full Text Available D01465 Drug Nizofenone fumarate (JAN); Ekonal (TN) C21H21ClN4O3. C4H4O4 528.1412 528.9416 D01465 ... OANALEPTICS N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD ... AND NOOTROPICS N06BX Other psychostimulants and no ...

  18. Drug: D01876 [KEGG MEDICUS

    Full Text Available D01876 Drug Pipradrol hydrochloride (JAN) C18H21NO. HCl 303.139 303.8264 D01876.gif ATC code: N0 ... OANALEPTICS N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD ... AND NOOTROPICS N06BX Other psychostimulants and no ...

  19. Drug: D07496 [KEGG MEDICUS

    Full Text Available D07496 Drug Befunolol (INN) C16H21NO4 291.1471 291.3422 D07496.gif Glaucoma ... treatment; beta-Adre ... 3] S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01E ANTIGLAUCOMA ... PREPARATIONS AND MIOTICS S01ED Beta blocking agent ...

  20. Drug: D08312 [KEGG MEDICUS

    Full Text Available D08312 Drug Oxetorone (INN) C21H21NO2 319.1572 319.3969 D08312.gif Antimigraine ATC...SICS N02C ANTIMIGRAINE PREPARATIONS N02CX Other antimigraine preparations N02CX06 Oxetorone D08312 Oxetorone

  1. Liquid crystalline critical dynamics in decylammonium chloride

    Collective chain dynamics and phase transitions in a model biomembrane, decylammonium chloride (C10H21NH3Cl), were studied by means of proton nuclear magnetic resonance. Our measurements sensitively reflect the critical dynamics associated with the smectic C to smectic A transition of the lipid bilayer

  2. 78 FR 9929 - Current Traumatic Brain Injury State Implementation Partnership Grantees; Non-Competitive One...


    ... Implementation Partnership Grantees; Non-Competitive One-Year Extension Funds AGENCY: Health Resources and...-Competitive One-Year Extension Funds for Current Traumatic Brain Injury (TBI) State Implementation Partnership... a non-competitive one-year extension for the State Implementation Partnerships (H21) awards...

  3. 78 FR 981 - Agency Information Collection Activities; Renewal of a Currently Approved Collection; and Comment...


    ... relationship to institution; k. Officer; l. Owner or Controlling Shareholder; z. Other ] 22. If item 21h, 21i... introducing brokers in commodities, insurance companies, mutual funds, money services businesses, and casinos... cashers, and dealers in foreign exchange), casinos and card clubs, and insurance companies to file...

  4. 1-Methylamino-3-(2,4,6-trimethylphenylpropan-2-ol

    Abel M. Maharramov


    Full Text Available The methylaminopropyl chain in the title compound, C13H21NO, adopts an extended zigzag conformation and the N atom shows a trigonal coordination. The N atom acts as hydrogen-bond acceptor to the hydroxy group of an adjacent molecule, generating a helical chain running along the b axis. The amino H atom is not involved in hydrogen bonding.

  5. 1-Methylamino-3-(2,4,6-trimethylphenyl)propan-2-ol

    Maharramov, Abel M.; Ali N. Khalilov; Atash V. Gurbanov; Allahverdiyev, Mirze A.; Seik Weng Ng


    The methylaminopropyl chain in the title compound, C13H21NO, adopts an extended zigzag conformation and the N atom shows a trigonal coordination. The N atom acts as hydrogen-bond acceptor to the hydroxy group of an adjacent molecule, generating a helical chain running along the b axis. The amino H atom is not involved in hydrogen bonding.

  6. SwissProt search result: AK072740 [KOME

    Full Text Available AK072740 J023134H21 (Q93WU2) Eugenol O-methyltransferase (EC ((Iso)eugenol... O-methyltransferase EOMT1) (S-adenosysl-L-methionine:(Iso)eugenol O-methyltransferase EOMT1) EOMT1_OCIBA 3e-67 ...

  7. SwissProt search result: AK072740 [KOME

    Full Text Available AK072740 J023134H21 (Q93WU3) Chavicol O-methyltransferase (EC ((Iso)eugenol... O-methyltransferase CVOMT1) (S-adenosysl-L-methionine:(Iso)eugenol O-methyltransferase CVOMT1) CVMT1_OCIBA 3e-65 ...

  8. Drug: D07872 [KEGG MEDICUS

    Full Text Available D07872 Drug Dosulepin (INN); Dothiepin; Dothep (TN) C19H21NS 295.1395 295.4417 D07872.gif Antidepress...ant, trycyclic ATC code: N06AA16 Tricyclic antidepressants serotonin transporter inhibitor... [HSA:6532] [KO:K05037]; noradrenalin transporter inhibitor [HSA:6530] [KO:K05035] map07027 Antidepressants

  9. Drug: D00537 [KEGG MEDICUS

    Full Text Available D00537 Drug Topiramate (JAN/USAN/INN); Topamax (TN); Trokendi xr (TN) C12H21NO8S 339.0988 339.36 ... BAergic synapse hsa04730(2890+2891+2892) Long-term depression ... Enzyme: CYP3A4 [HSA:1576] CYP inhibition: CYP2C19 ...

  10. 2-[2-(2-Hydroxyethoxyphenyl]-4,4,5,5-tetramethyl-2-imidazoline-1-oxyl 3-oxide

    Lin-Lin Jing


    Full Text Available In the title compound, C15H21N2O4, the nitronyl nitroxide unit displays a twisted conformation. The crystal structure is stabilized by non-classical C—H...O and C—H...π hydrogen bonds, which build up a three-dimensional network.

  11. Dicty_cDB: FC-AR22 [Dicty_cDB

    Full Text Available mRNA sequence. 50 0.023 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing seed Prunus dulcis cDNA clo...BAC, RP23-158F1, complete sequence. 48 0.092 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing

  12. Drug: D06632 [KEGG MEDICUS

    Full Text Available , major depression, and schizophrenia 5-HT2A-receptor antagonist [HSA:3356] [KO:K04157] hsa04020(3356) Calci...D06632 Drug Pruvanserin (USAN/INN) C22H21FN4O 376.1699 376.4267 D06632.gif Insomnia

  13. SwissProt search result: AK070181 [KOME

    Full Text Available AK070181 J023043H21 (P09095) Tyrocidine synthetase I [Includes: ATP-dependent D-phenylala...nine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC] TYCA_BREPA 2e-19 ...

  14. Drug: D06676 [KEGG MEDICUS

    Full Text Available D06676 Drug Raltegravir (USAN/INN); MK-0518 C20H21FN6O5 444.1557 444.4163 D06676.gif Antivirals ... [DS:H00406] ATC code: J05AX08 HIV -1 integrase inhibitor Enzyme: UGT1A1 [HSA:54658] m ... ap07053 Anti-HIV ... agents Anatomical Therapeutic Chemical (ATC) class ...

  15. (E-2,2′-[3-(2-Nitrophenylprop-2-ene-1,1-diyl]bis(3-hydroxycyclohex-2-en-1-one

    Joo Hwan Cha


    Full Text Available In the title compound, C21H21NO6, each of the cyclohexenone rings adopts a half-chair conformation. Each of the pairs of hydroxy and carbonyl O atoms are oriented to allow for the formation of intramolecular O—H...O hydrogen bonds, which are typical of xanthene derivatives.

  16. Drug: D00379 [KEGG MEDICUS

    Full Text Available D00379 Drug Tolazamide (JP16/USP/INN); Tolinase (TN) C14H21N3O3S 311.1304 311.3998 D00379.gif Antidiabetic...od Glucose Regulators Antidiabetic Agents Tolazamide D00379 Tolazamide (JP16/USP/INN) Target-based classific

  17. Drug: D10200 [KEGG MEDICUS

    Full Text Available D10200 Drug Ipragliflozin L-proline (JAN) C21H21FO5S. C5H9NO2 519.1727 519.5823 D10200.gif Antidiabetic... [DS:H00409] sodium glucose co-transporter2 (SGLT2) inhibitor [HSA:6524] [KO:K14382] map07051 Antidiabetic

  18. Drug: D10196 [KEGG MEDICUS

    Full Text Available D10196 Drug Ipragliflozin (INN) C21H21FO5S 404.1094 404.4518 D10196.gif Antidiabetic... [DS:H00409] sodium glucose co-transporter2 (SGLT2) inhibitor [HSA:6524] [KO:K14382] map07051 Antidiabetics

  19. Drug: D07875 [KEGG MEDICUS

    Full Text Available D07875 Drug Doxepin (INN); Sinequan (TN) C19H21NO 279.1623 279.3761 D07875.gif Antidepressant, t ... r08303] N NERVOUS SYSTEM N06 PSYCHOANALEPTICS N06A ANTIDEPRESSANTS ... N06AA Non-selective monoamine reuptake inhibitors ... Doxepin (INN) USP drug classification [BR:br08302] Antidepressants ... Tricyclics Doxepin D07875 Doxepin (INN) Anxiolytic ...

  20. Drug: D00814 [KEGG MEDICUS

    Full Text Available D00814 Drug Doxepin hydrochloride (USP); Sinequan (TN); Zonalon (TN) C19H21NO. HCl 315.139 315.8 ... r08303] N NERVOUS SYSTEM N06 PSYCHOANALEPTICS N06A ANTIDEPRESSANTS ... N06AA Non-selective monoamine reuptake inhibitors ... hloride (USP) USP drug classification [BR:br08302] Antidepressants ... Tricyclics Doxepin D00814 Doxepin hydrochloride (U ...

  1. Drug: D00484 [KEGG MEDICUS

    Full Text Available D00484 Drug Protriptyline hydrochloride (USP); Vivactil (TN) C19H21N. HCl 299.1441 299.8377 D004 ... r08303] N NERVOUS SYSTEM N06 PSYCHOANALEPTICS N06A ANTIDEPRESSANTS ... N06AA Non-selective monoamine reuptake inhibitors ... hloride (USP) USP drug classification [BR:br08302] Antidepressants ... Tricyclics Protriptyline D00484 Protriptyline hydr ...

  2. Drug: D08447 [KEGG MEDICUS

    Full Text Available D08447 Drug Protriptyline (INN) C19H21N 263.1674 263.3767 D08447.gif Antidepressant, tricyclic S ... r08303] N NERVOUS SYSTEM N06 PSYCHOANALEPTICS N06A ANTIDEPRESSANTS ... N06AA Non-selective monoamine reuptake inhibitors ... ptyline (INN) USP drug classification [BR:br08302] Antidepressants ... Tricyclics Protriptyline D08447 Protriptyline (INN ...

  3. Complete genome sequence and comparison of two Shiga toxin-producing Escherichia coli O104 isolates

    Shiga toxin-producing Escherichia coli (STEC) O104 strains have been associated with sporadic cases of illness and have caused outbreaks associated with milk and sprouts. E. coli O104:H21 caused an outbreak associated with milk in the U.S. in 1994. In this study, next generation sequencing techno...

  4. Drug: D00901 [KEGG MEDICUS

    Full Text Available D00901 Drug Rimantadine hydrochloride (USAN); Flumadine (TN) C12H21N. HCl 215.1441 215.7628 D009 ... TC code: J05AC02 Adamantane derivative Indication: Influenza ... A influenza ... A M2 proton channel blocker [VG:NC_004 ... P drug classification [BR:br08302] Antivirals Anti-influenza ... Agents Rimantadine D00901 Rimantadine hydrochlorid ...

  5. Drug: D08757 [KEGG MEDICUS

    Full Text Available Neurolite (TN) C12H21N2O5S2. Tc. 433.9956 436.3417 Therapeutic category: 4300 Therapeutic category of drugs... in Japan [BR:br08301] 4 Agents affecting cellular function 43 Radioactive drugs 430 Radioactive drugs 4300 Radioactive drugs

  6. Drug: D09024 [KEGG MEDICUS

    Full Text Available D09024 Drug Totrombopag choline (USAN) C25H21N8O2. C5H14NO 569.2863 569.6574 D09024.gif Treatment of chemoth...erapy-induced thrombocytopenia, treatment of thrombocytopenia associated liver dise

  7. Drug: D02968 [KEGG MEDICUS

    Full Text Available 2968.gif Antiemetic in chemotherapy-induced emesis; Antidepressant; Treatment of psychiatric conditions [sub...D02968 Drug Aprepitant (JAN/USAN/INN); Emend (TN) C23H21F7N4O3 534.1502 534.4267 D0

  8. EST Table: FY018488 [KAIKOcDNA[Archive

    Full Text Available FY018488 rbmov22h21 11/11/04 97 %/265 aa ref|NP_001040121.1| endothelial-monocyte activating pol ... 57 %/166 aa F58B3.5c#CE44546#WBGene00003415#locus:mars - 1#status:Confirmed#UniProt:D3YT56#protein_id:CBK1 ...

  9. Drug: D08045 [KEGG MEDICUS

    Full Text Available D08045 Drug Hydrocodone (INN); Dihydrocodeinone C18H21NO3 299.1521 299.3642 D08045.gif Antitussi ... assification [BR:br08303] R RESPIRATORY SYSTEM R05 COUGH ... AND COLD PREPARATIONS R05D COUGH ... SUPPRESSANTS, EXC ...

  10. Drug: D00195 [KEGG MEDICUS

    Full Text Available D00195 Drug Codeine (USP); Codeine hydrate C18H21NO3. H2O 317.1627 317.3795 D00195.gif Papaver s ... assification [BR:br08303] R RESPIRATORY SYSTEM R05 COUGH ... AND COLD PREPARATIONS R05D COUGH ... SUPPRESSANTS, EXC ...

  11. Drug: D05804 [KEGG MEDICUS

    Full Text Available D05804 Drug Sarizotan hydrochloride (USAN); EMD 128130 C22H21FN2O. HCl 384.1405 384.8743 D05804. ... gif Treatment-associated dyskinesia in Parkinson 's disease 5-HT1A-receptor agonist [HSA:3350] [KO:K ...

  12. 1,5,6-Triphenyl-8-oxa-7-selena-6-phosphabicyclo[3.2.1]octane-6-selone

    Yang Li


    Full Text Available The structure of the title compound, C23H21OPSe2, consists of fused puckered five- and six-membered rings, PSeC2O and C5O, respectively, with a C2O bridgehead. The C5O ring adopts a chair conformation, whilst the C2PSeO ring has an envelope conformation.

  13. Dicty_cDB: VHE651 [Dicty_cDB

    Full Text Available VH (Link to library) VHE651 (Link to dictyBase) - - - Contig-U16102-1 - (Link to Original site) ... N DY830034 |DY830034.1 CTOY564.b1_H21.ab1 CTO(XYZ) dandelion ... Taraxacum officinale cDNAclone CTOY564, mRNA seque ...

  14. Drug: D06633 [KEGG MEDICUS

    Full Text Available 33.gif Insomnia, major depression, and schizophrenia 5-HT2A-receptor antagonist [HSA:3356] [KO:K04157] hsa04...D06633 Drug Pruvanserin hydrochloride (USAN) C22H21FN4O. HCl 412.1466 412.8877 D066

  15. Drug: D07756 [KEGG MEDICUS

    Full Text Available D07756 Drug Cyamemazine tartrate; Tercian (TN) C19H21N3S. C4H6O6 473.1621 473.542 D0775...e-chain N05AA06 Cyamemazine D07756 Cyamemazine tartrate CAS: 93841-82-8 PubChem: 51092048 LigandBox: D0775

  16. EST Table: FY011605 [KAIKOcDNA[Archive

    Full Text Available FY011605 rbmov3h21 11/11/04 49 %/238 aa ref|XP_970998.1| PREDICTED: similar to Evolution..._970998.1| PREDICTED: similar to Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial [Tribolium castaneum] FY016706 bmov ...

  17. EST Table: FY000874 [KAIKOcDNA[Archive

    Full Text Available FY000874 bmov3h21 11/11/04 65 %/109 aa ref|XP_970998.1| PREDICTED: similar to Evolution...%/109 aa gi|91094187|ref|XP_970998.1| PREDICTED: similar to Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial [Tribolium castaneum] FS756091 bmov ...

  18. Drug: D00846 [KEGG MEDICUS

    Full Text Available D00846 Mixture, Drug Hydrocodone bitartrate - acetaminophen ... mixt; Vicodin (TN) C18H21NO3. C8H9NO ... 136 D00846.gif Hydrocodone bitartrate [DR:D03725], Acetaminophen ... [DR:D00217] CAS: 330988-71-1 PubChem: 7847911 Liga ...

  19. Drug: D08687 [KEGG MEDICUS

    Full Text Available D08687 Drug Ziprasidone (INN); Zipradon (TN) C21H21ClN4OS 412.1125 412.9356 D08687.gif Neurolept ... tion/Atypical Ziprasidone D08687 Ziprasidone (INN) Bipolar ... Agents Bipolar ... Agents, Other Ziprasidone D08687 Zi ...

  20. Drug: D00706 [KEGG MEDICUS

    Full Text Available D00706 Drug Zolpidem tartrate (JP16/USAN); Ambien (TN); Intermezzo (TN) (C19H21N3O)2. C4H6O6 764 ... e (JP16/USAN) USP drug classification [BR:br08302] Sleep ... Disorder Agents GABA Receptor Modulators Zolpidem ...

  1. Drug: D08690 [KEGG MEDICUS

    Full Text Available D08690 Drug Zolpidem (INN); Sanval (TN) C19H21N3O 307.1685 307.3895 D08690.gif Hypnotic Same as: ... olpidem (INN) USP drug classification [BR:br08302] Sleep ... Disorder Agents GABA Receptor Modulators Zolpidem ...

  2. Drug: D02689 [KEGG MEDICUS

    Full Text Available D02689 Drug Ramelteon (JAN/USAN/INN); Rozerem (TN) C16H21NO2 259.1572 259.3434 D02689.gif Treatm ... ent of sleep ... disorders Therapeutic category: 1190 ATC code: N05 ... JAN/USAN/INN) USP drug classification [BR:br08302] Sleep ... Disorder Agents Sleep ... Disorders, Other Ramelteon D ...

  3. Drug: D08249 [KEGG MEDICUS

    Full Text Available D08249 Drug Naloxone ... (INN); DBL Naloxone ... (TN) C19H21NO4 327.1471 327.3743 D08249.gif Antidote, m ... OTHER THERAPEUTIC PRODUCTS V03AB Antidotes V03AB15 Naloxone ... D08249 Naloxone ... (INN) USP drug classification [BR: ... ance Abuse Treatment Agents Opioid Reversal Agents Naloxone ... D08249 Naloxone ... (INN) Target-based classification ...

  4. 2,5,11,14-Tetraoxa-8-azadispiro[13.4.0]nonadeca-15,17,19-triene

    Quanying Gan


    Full Text Available The title compound, C14H21NO4, has been synthesized from o-dihydroxybenzene by a three-step reaction. There are two chemically equal but crystallographically independent molecules in the asymmetric unit. The crystal packing is governed by C—H...O hydrogen bonds and C—H...π interactions, forming an infinite network.

  5. (E-N′-[4-(Dimethylaminobenzylidene]-2-(4-methylphenoxyacetohydrazide

    M. K. Usha


    Full Text Available In the title compound, C18H21N3O2, the dihedral angle between the benzene rings is 68.85 (11°. In the crystal, the molecules are linked by C—H...O and N—H...O hydrogen bonds, as well as weak C—H...π contacts, forming a three-dimensional supramolecular architecture.

  6. Experiment list: SRX129114 [Chip-atlas[Archive

    Full Text Available of Extraction=Effusion, Pleural|Tissue Diagnosis=Carcinoma Small Cell 36207012,86.3,16.6,1575 GSM894106: H21...71 WCE 3; Homo sapiens; ChIP-Seq source_name=Small Cell Lung Carcinoma || chip antibody=None || cell type=H2

  7. Hydrogenation/Dehydrogenation Performances of the MgH2-WS2 Composites

    WANG Jiasheng; ZHANG Wei; CHENG Ying; KE Dandan; HAN Shumin


    The hydrogenation/dehydrogenation kinetics and thermodynamic behaviors of the MgH2-WS2 composites were investigated. The TPD (Temperature-Programmed-Desorption) curves showed that the onset dehydrogenation temperature of the MgH2 + 20wt% WS2 composite was 615 K, 58 K lower than that of the pristine MgH2. The kinetic measurements showed that within 21 min, the MgH2 + 20wt% WS2 composite could absorb 2.818wt% at 423 K, and release 4.244 wt% of hydrogen at 623 K, while the hydriding/dehydriding capacity of MgH2 reached only 0.979wt% and 2.319wt% respectively under identical conditions. The improvement of hydrogenation/dehydrogenation performances for the composite was attributed to the co-catalytic effect between the new phases W and MgS which formed during the ball-milling process.

  8. Angular Momentum and Topological Dependence of Kepler's Third Law in the Broucke-Hadjidemetriou-Hénon Family of Periodic Three-Body Orbits

    Janković, Marija R.; Dmitrašinović, V.


    We use 57 recently found topological satellites of Broucke-Hadjidemetriou-Hénon's periodic orbits with values of the topological exponent k ranging from k =3 to k =58 to plot the angular momentum L as a function of the period T , with both L and T rescaled to energy E =-0.5 . Upon plotting L (T /k ) we find that all our solutions fall on a curve that is virtually indiscernible by the naked eye from the L (T ) curve for nonsatellite solutions. The standard deviation of the satellite data from the sixth-order polynomial fit to the progenitor data is σ =0.13 . This regularity supports Hénon's 1976 conjecture that the linearly stable Broucke-Hadjidemetriou-Hénon orbits are also perpetually, or Kol'mogorov-Arnol'd-Moser, stable.

  9. Wave motions in the lower thermosphere during the Energy Budget Campaign 1980 from three locations in the northern hemisphere

    Cevolani, G.; Dardi, A.; Formiggini, C. (Consiglio Nazionale delle Ricerche, Bologna (Italy). Ist. FISBAT); Kingsley, S.P.; Muller, H.G. (Sheffield Univ. (UK). Dept. of Physics)

    Simultaneous meteor radar wind observations were made at Budrio (Italy, 45/sup 0/ N), Sheffield (U.K., 53/sup 0/ N) and Stornoway (U.K., 58/sup 0/ N) during the Energy Budget Campaign (EBC), November-December 1980, in the altitude region between 75 and 115 km. Wind results are presented in terms of prevailing components and oscillations of different time scales: Tidal (8, 12 and 24 h), gravity ((3/6) h) and planetary ((2/10) days) waves. The seasonal variation of the prevailing zonal components observed at the three stations in previous years shows the same maxima of Summer and Winter, as well as the equinoctial minima exhibited by the CIRA 1972 model for 50/sup 0/ N. The data show marked tidal activity with the semi-diurnal tide which exceeds in amplitude any other mode in the wind spectra.

  10. Angular momentum and topological dependence of Kepler's Third Law in the Broucke-Hadjidemetriou-H\\'enon family of periodic three-body orbits

    Janković, Marija R


    We use 57 recently found topological satellites of Broucke-Hadjidemetriou-Henon's periodic orbits with values of the topological exponent $k$ ranging from $k$ = 3 to $k$ = 58 to plot the angular momentum $L$ as a function of the period $T$, with both $L$ and $T$ rescaled to energy $E=-\\frac12$. Upon plotting $L(T/k)$ we find that all our solutions fall on a curve that is virtually indiscernible by naked eye from the $L(T)$ curve for non-satellite solutions. The standard deviation of the satellite data from the sixth-order polynomial fit to the progenitor data is $\\sigma = 0.13$. This regularity supports Henon's 1976 conjecture that the linearly stable Broucke-Hadjidemetriou-Henon orbits are also perpetually, or Kolmogorov-Arnold-Moser stable.

  11. Methods for reduction of radionuclides incorporated into the body

    Small-scale (laboratories and hospitals) to global radioactive contamination may contribute to incorporation of radionuclides in the living body. In real accidents, many radionuclides are occasionally incorporated simultaneously into the body. Therefore, it is important to know the kinds of radionuclides, chemical form at the incorporation, and presence status and behavior of radionuclides in the body. Because there is interaction between agents for reducing radioactive contamination, the reduction mechanism of radionuclide in the body should be considered when such agents are used in the combination manner. The purpose of this report is to discuss chemical methods for reducing radionuclides that are orally incorporated into the body. These methods are described in terms of dilution, complex production, adsorption, metabolism derangement, and others. I-131, Cs-137, Sr-90, and Ru-106, which are influential radionuclides for the human body, are especially referred to. (N.K.) 58 refs

  12. Two One-Parameter Special Geometries

    Braun, Volker; de la Ossa, Xenia


    The special geometries of two recently discovered Calabi-Yau threefolds with $h^{11}=1$ are analyzed in detail. These correspond to the 'minimal three-generation' manifolds with $h^{21}=4$ and the `24-cell' threefolds with $h^{21}=1$. It turns out that the one-dimensional complex structure moduli spaces for these manifolds are both very similar and surprisingly complicated. Both have 6 hyperconifold points and, in addition, there are singularities of the Picard-Fuchs equation where the threefold is smooth but the Yukawa coupling vanishes. Their fundamental periods are the generating functions of lattice walks, and we use this fact to explain why the singularities are all at real values of the complex structure.

  13. Studies on the relationship between lectin binding carbohydrates and different strains of Leishmania from the New World

    J. Schottelius; S. C. Gonçalves da Costa


    The culture forms of L. mexicana pifanoi (LRC L-90), L. mexicana mexicana (LRC L-94, M-379); L. braziliensis braziliensis (LRC L-77, L-1, M-2903, H-LSS) and L. mexicana amazonensis (H-JMMO, M-JOF, H-21, H-PLL,M-1696) were tested with the following lectins: Canavalia ensiformis, Ricinus communis-120, Axinella polypoides, Phaseolus vulgaris, Evonymus europaeus, lotus tetragonolobus, Dolichos biflorus, Aaptos papillata II, Laburnum alpinum, Ulex europaeus, Arachis hypogaea and Soja hispida. All ...

  14. Drug: D00415 [KEGG MEDICUS

    Full Text Available D00415 Drug Zolmitriptan (JAN/USAN/INN); Zomig (TN) C16H21N3O2 287.1634 287.3568 D00415.gif Antimigraine...A:1544], MAOA [HSA:4128] map07048 Antimigraines map07211 Serotonin receptor agonists/antagonists Therapeutic...N) USP drug classification [BR:br08302] Antimigraine Agents Serotonin (5-HT) 1b/1

  15. Drug: D00676 [KEGG MEDICUS

    Full Text Available epro (TN); Zecutity (TN) C14H21N3O2S. C4H6O4 413.1621 413.4885 D00676.gif Antimigraine Therapeutic category:...sa04726(3351+3352) Serotonergic synapse Enzyme: MAOA [HSA:4128] map07048 Antimigraines map07211 Serotonin re...umatriptan D00676 Sumatriptan succinate (JAN/USAN) USP drug classification [BR:br08302] Antimigraine

  16. 1-Methyl­amino-3-(2,4,6-trimethyl­phen­yl)propan-2-ol

    Maharramov, Abel M.; Ali N. Khalilov; Atash V. Gurbanov; Allahverdiyev, Mirze A.; Ng, Seik Weng


    The methyl­amino­propyl chain in the title compound, C13H21NO, adopts an extended zigzag conformation and the N atom shows a trigonal coordination. The N atom acts as hydrogen-bond acceptor to the hy­droxy group of an adjacent mol­ecule, generating a helical chain running along the b axis. The amino H atom is not involved in hydrogen bonding.

  17. 1-Methyl-amino-3-(2,4,6-trimethyl-phen-yl)propan-2-ol.

    Maharramov, Abel M; Khalilov, Ali N; Gurbanov, Atash V; Allahverdiyev, Mirze A; Ng, Seik Weng


    The methyl-amino-propyl chain in the title compound, C(13)H(21)NO, adopts an extended zigzag conformation and the N atom shows a trigonal coordination. The N atom acts as hydrogen-bond acceptor to the hy-droxy group of an adjacent mol-ecule, generating a helical chain running along the b axis. The amino H atom is not involved in hydrogen bonding. PMID:21754075

  18. 1-Methyl­amino-3-(2,4,6-trimethyl­phen­yl)propan-2-ol

    Maharramov, Abel M.; Khalilov, Ali N.; Gurbanov, Atash V.; Allahverdiyev, Mirze A.; Ng, Seik Weng


    The methyl­amino­propyl chain in the title compound, C13H21NO, adopts an extended zigzag conformation and the N atom shows a trigonal coordination. The N atom acts as hydrogen-bond acceptor to the hy­droxy group of an adjacent mol­ecule, generating a helical chain running along the b axis. The amino H atom is not involved in hydrogen bonding. PMID:21754075

  19. Drug: D01966 [KEGG MEDICUS

    Full Text Available D01966 Drug Ezetimibe (JAN/USAN/INN); Zetia (TN) C24H21F2NO3 409.149 409.4252 D01966.gif Antihyp ... erlipidemic [intestinal cholesterol absorption ... inhibitor] Therapeutic category: 2189 ATC code: C1 ... 881] [KO:K14461] hsa04975(29881) Fat digestion and absorption ... Enzyme: UGT [KO:K00699] Transporter: SLCO1B1 [HSA: ...

  20. Drug: D08288 [KEGG MEDICUS

    Full Text Available D08288 Drug Nortriptyline (INN); Nortrilen (TN) C19H21N 263.1674 263.3767 D08288.gif Antidepress...ant, tricyclic Same as: C07274 ATC code: N06AA10 Tricyclic antidepressants serotonin transporte... Serotonergic synapse Enzyme: CYP2D6 [HSA:1565] Genomic biomarker: CYP2D6 [HSA:1565] map07027 Antidepress... D08288 Nortriptyline (INN) USP drug classification [BR:br08302] Antidepressants Tricyclics Nortriptyline D0

  1. Drug: D08463 [KEGG MEDICUS

    Full Text Available D08463 Drug Rabeprazole (INN); Eraloc (TN) C18H21N3O3S 359.1304 359.4426 D08463.gif Enzyme inhib ... inhibitor Same as: C07864 ATC code: A02BC04 proton pump ... inhibitor (PPI) H+/K+ exchanging, alpha polypeptid ... TRO-OESOPHAGEAL REFLUX DISEASE (GORD) A02BC Proton pump ... inhibitors A02BC04 Rabeprazole D08463 Rabeprazole ...

  2. 2-[4-(2-Hydroxyethoxyphenyl]-4,4,5,5-tetramethyl-2-imidazoline-1-oxyl 3-oxide

    Lin-Lin Jing


    Full Text Available In the title compound, C15H21N2O4, the imidazoline ring displays a twisted conformation. The dihedral angle between the mean plane of the imidazoline ring and the benzene ring is 33.50 (12°. In the crystal, molecules are connected by O—H...O hydrogen bonds, forming a zigzag chain along the c axis. The chains are linked by C—H...O and C—H...π interactions.

  3. 2-[3-Hydroxy-4-(2-hydroxyethoxyphenyl]-4,4,5,5-tetramethyl-2-imidazoline-1-oxyl 3-oxide

    Hui-Ping Ma


    Full Text Available In the title compound, C15H21N2O5, the imidazoline ring displays a twisted conformation. The mean plane of the imidazoline ring makes a dihedral angle of 22.55 (5° with the benzene ring. In the crystal, O—H...O and C—H...O hydrogen bonds link the molecules into a layer parallel to the bc plane.

  4. Dicty_cDB: FC-IC0858 [Dicty_cDB

    Full Text Available AC, RP23-158F1, complete sequence. 48 0.060 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing...6.1 Lupinus luteus mRNA for ribosomal protein L30. 48 0.060 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing

  5. Dicty_cDB: SSH878 [Dicty_cDB

    Full Text Available M library Mus musculus genomic clone UUGC1M0399K06 R, DNA sequence. 48 0.076 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing...nce. 48 0.076 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing seed Prunus dulcis cDNA clone PA__Ea00

  6. 30 aastat pärast diktatuuri hukku pole rahu Hispaaniasse naasnud / Priit Kivi

    Kivi, Priit


    Ilmunud ka: Postimees : na russkom jazõke Ajal. Postimees : na russkom jazõke lüh. 21. nov., lk 11. Hispaania paremäärmuslased süüdistavad sotsialistlikku valitsust riigi tahtlikus lõhkumises. Franco-kummardajate terava vastuseisu on pälvinud valitsuse toetus samasooliste abielule, Kataloonia iseseisvuspüüdluste toetamine ning planeeritav õppekava, mis vähendab usuõpetuse tähtsust koolides. Lisa: Kindral Francisco Franco

  7. Spectroscopic investigation of phase transitions in 1-nonanol and 1-decanol

    Chernolevska, Yelyzaveta; Pogorelov, Valeriy; Doroshenko, Iryna; Doroshenko, Olena; Sablinskas, Valdas; Balevicius, Vytautas


    FTIR spectra of monohydric alcohols 1-nonanol (C9H19OH) and 1-decanol (C10H21OH) were registered in the spectral region from 500 cm-1 to 4000 cm-1 at temperatures from -50 to + 25 {\\deg}C for 1-nonanol and +100 {\\deg}C for 1-decanol. Temperature-induced spectra changes were compared for these two alcohols. The authors link the observed changes with the transformations of cluster structure occurring during phase transitions.

  8. 5-Cyclohexyl-2-(3-fluorophenyl-3-methylsulfinyl-1-benzofuran

    Hong Dae Choi


    Full Text Available In the title compound, C21H21FO2S, the cyclohexyl ring adopts a chair conformation. The 3-fluorophenyl ring makes a dihedral angle of 38.38 (6° with the mean plane [r.m.s. deviation = 0.010 (1 Å] of the benzofuran fragment. In the crystal, molecules are linked by weak C—H...O hydrogen bonds.

  9. Drug: D01665 [KEGG MEDICUS

    Full Text Available D01665 Drug Voglibose (JP16/USAN/INN); Basen (TN) C10H21NO7 267.1318 267.2762 D01665.gif metabolism hsa04973(8972) Carbohydrate digestion and absorption map07051 Antidiabetics Therapeutic catego...ry of drugs in Japan [BR:br08301] 3 Agents affecting metabolism 39 Other agents affecting metabolism 396 Antidiabetic

  10. Napropamide.

    Cho, Seonghwa; Kim, Jineun; Jeon, Youngeun; Kim, Tae Ho


    THE TITLE COMPOUND [SYSTEMATIC NAME: N,N-diethyl-2-(naphthalen-1-yl-oxy)propanamide], C17H21NO2, crystallizes with two independent mol-ecules in the asymmetric unit in which the dihedral angles between the naphthalene ring systems and the amide groups are 88.1 (9) and 88.7 (3)°. Four C-H⋯O hydrogen bonds stabilize the crystal structure. PMID:24109304

  11. Napropamide

    Cho, Seonghwa; Kim, Jineun; Jeon, Youngeun; Kim, Tae Ho


    The title compound [systematic name: N,N-diethyl-2-(naphthalen-1-yl­oxy)propanamide], C17H21NO2, crystallizes with two independent mol­ecules in the asymmetric unit in which the dihedral angles between the naphthalene ring systems and the amide groups are 88.1 (9) and 88.7 (3)°. Four C—H⋯O hydrogen bonds stabilize the crystal structure.

  12. Napropamide

    Tae Ho Kim; Youngeun Jeon; Jineun Kim; Seonghwa Cho


    The title compound [systematic name: N,N-diethyl-2-(naphthalen-1-yloxy)propanamide], C17H21NO2, crystallizes with two independent molecules in the asymmetric unit in which the dihedral angles between the naphthalene ring systems and the amide groups are 88.1 (9) and 88.7 (3)°. Four C—H...O hydrogen bonds stabilize the crystal structure.

  13. Napropamide

    Tae Ho Kim


    Full Text Available The title compound [systematic name: N,N-diethyl-2-(naphthalen-1-yloxypropanamide], C17H21NO2, crystallizes with two independent molecules in the asymmetric unit in which the dihedral angles between the naphthalene ring systems and the amide groups are 88.1 (9 and 88.7 (3°. Four C—H...O hydrogen bonds stabilize the crystal structure.

  14. Teleseismic observations of the 1976 Friuli, Italy earthquake sequence

    Cipar, John


    Teleseismic long-period body and surface waves radiated by the May 6, 1976 Friuli, Italy earthquake and its principal aftershock of September 15, 1976 (09h 21 m) are studied to determine source characteristics. Focal mechanisms along with geological evidence suggest that both events represent the underthrusting of the Friuli Plain beneath the southern Alps. The depths of both earthquakes, estimated by matching synthetic body-wave seismograms to observations, are found to lie between 6 and 10 ...

  15. Drug: D08483 [KEGG MEDICUS

    Full Text Available D08483 Drug Rimantadine (INN) C12H21N 179.1674 179.3018 D08483.gif Antiviral [DS:H00398] Same as ... : C07236 ATC code: J05AC02 Adamantane derivative influenza ... A M2 proton channel blocker [VG:NC_004907_1 NC_002 ... P drug classification [BR:br08302] Antivirals Anti-influenza ... Agents Rimantadine D08483 Rimantadine (INN) Antiin ...

  16. 2,4-Bis(morpholin-4-yl-6-phenoxy-1,3,5-triazine

    Jasmine P. Vennila


    Full Text Available In the title compound, C17H21N5O3, the dihedral angle between the triazine and the phenyl ring is 80.31 (11°. One of the morpholine rings is disordered over two orientations with site occupancies of 0.762 (10 and 0.238 (10. Both morpholine rings in the molecule adopt chair conformations.

  17. (2Z-1-(5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl-3-(4-methylanilinobut-2-en-1-one

    Edward R. T. Tiekink


    Full Text Available A twist is evident in the title compound, C21H21N3O2, the dihedral angle between the terminal six-membered rings being 29.46 (10°; the linked five- and six-membered rings are coplanar [1.30 (11°]. The carbonyl O atom accepts intramolecular hydrogen bonds from the adjacent hydroxy and amine groups. The three-dimensional crystal packing is achieved through C—H...π interactions.

  18. (2Z)-1-(5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-3-(4-methylanilino)but-2-en-1-one

    Tiekink, Edward R. T.; Al-Youbi, Abdulrahman O.; Seik Weng Ng; Asiri, Abdullah M.


    A twist is evident in the title compound, C21H21N3O2, the dihedral angle between the terminal six-membered rings being 29.46 (10)°; the linked five- and six-membered rings are coplanar [1.30 (11)°]. The carbonyl O atom accepts intramolecular hydrogen bonds from the adjacent hydroxy and amine groups. The three-dimensional crystal packing is achieved through C—H...π interactions.

  19. Drug: D02477 [KEGG MEDICUS

    Full Text Available D02477 Drug Meclocycline sulfosalicylate (USP); Meclan (TN) C22H21ClN2O8. C7H6O6S 694.0872 695.0 ... sification [BR:br08303] D DERMATOLOGICALS D10 ANTI-ACNE ... PREPARATIONS D10A ANTI-ACNE ... PREPARATIONS FOR TOPIC ... AL USE D10AF Antiinfectives for treatment of acne ... D10AF04 Meclocycline D02477 Meclocycline sulfosali ...

  20. Drug: D02476 [KEGG MEDICUS

    Full Text Available D02476 Drug Meclocycline (USAN/INN) C22H21ClN2O8 476.0986 476.8637 D02476.gif Antibacterial ATC ... sification [BR:br08303] D DERMATOLOGICALS D10 ANTI-ACNE ... PREPARATIONS D10A ANTI-ACNE ... PREPARATIONS FOR TOPIC ... AL USE D10AF Antiinfectives for treatment of acne ... D10AF04 Meclocycline D02476 Meclocycline (USAN/INN ...

  1. 1,5-Dimethyl-4-(1-methyl-3-oxo-3-phenylprop-1-enylamino-2-phenyl-1H-pyrazol-3(2H-one

    Hualing Zhu


    Full Text Available In the title compound, C21H21N3O2, an intramolecular N—H...O interaction generates an S(6 ring, which stablizes the enamine–keto tautomer. The S(6 ring makes dihedral angles of 33.07 (7, 56.50 (8 and 38.59 (8°, respectively, with the benzoylacetone benzene ring and the antipyrine pyrazole and benzene rings.

  2. Drug: D07102 [KEGG MEDICUS

    Full Text Available D07102 Drug Alizapride (INN); Plitican (TN) C16H21N5O2 315.1695 315.3702 D07102.gif... DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS A03F PROPULSIVES A03FA Propulsives A03FA05 Alizapride D07102 Alizapride...amily Dopamine dopamine D2-receptor [HSA:1813] [KO:K04145] Alizapride [ATC:A03FA05] D07102 Alizapride

  3. Methyl 4,5-diacetoxy-1-oxo-2-phenylperhydro-4,6-epoxycyclopenta[c]pyridine-7-carboxylate ethanol solvate

    Victor N. Khrustalev


    Full Text Available The title compound, the product of an acid-catalysed Wagner–Meerwein skeletal rearrangement, crystallizes as an ethanol monosolvate, C20H21NO8·C2H6O. The title molecule comprises a fused tricyclic system containing two five-membered rings (cyclopentane and tetrahydrofuran in the usual envelope conformations and one six-membered ring (piperidinone adopting a flattened twist–boat conformation.

  4. Drug: D07758 [KEGG MEDICUS

    Full Text Available D07758 Drug Cyclobenzaprine (INN) C20H21N 275.1674 275.3874 D07758.gif Muscle relax...RELAXANTS, CENTRALLY ACTING AGENTS M03BX Other centrally acting agents M03BX08 Cyclobenzaprine D0775...8 Cyclobenzaprine (INN) USP drug classification [BR:br08302] Skeletal Muscle Relaxants Cyclobenzaprine D0775...8 Cyclobenzaprine (INN) CAS: 303-53-7 PubChem: 51092050 DrugBank: DB00924 LigandBox: D0775

  5. Dicty_cDB: CFG834 [Dicty_cDB

    Full Text Available one BACR23H21, complete sequence. 42 0.038 6 AI484136 |AI484136.1 EST248943 tomato resistant, Cornell Lycope...38 0.10 2 AI490786 |AI490786.1 EST241494 tomato shoot, Cornell Lycopersicon esculentum cDNA clone cLEB3H9 si....10 2 AI773934 |AI773934.1 EST255034 tomato resistant, Cornell Lycopersicon esculentum cDNA clone cLER8N1, m

  6. Dicty_cDB: AFK872 [Dicty_cDB

    Full Text Available ACR23H21, complete sequence. 42 0.051 6 AI484136 |AI484136.1 EST248943 tomato resistant, Cornell Lycopersico...12 2 AI490786 |AI490786.1 EST241494 tomato shoot, Cornell Lycopersicon esculentum cDNA clone cLEB3H9 similar... AI773934 |AI773934.1 EST255034 tomato resistant, Cornell Lycopersicon esculentum cDNA clone cLER8N1, mRNA s

  7. (E)-2-tert-Butyl-6-[(naphthalen-1-yl)iminomethyl]phenol

    Roghayieh Jamjah; Mehdi Nekoomanesh; Roya Zahedi; Gholamhossein Zohuri; Faramarz Afshar Taromi; Behrouz Notash


    The asymmetric unit of the title Schiff base compound, C21H21NO, contains two crystallographicaly independent molecules. The dihedral angles between the naphthalene mean plane and the benzene ring are 29.28 (8) and 26.92.(8)° in the two molecules. An intramolecular O—H...N hydrogen bond and weak intramolecular C—H...O hydrogen bonds stabilize the structure of each independent molecule.

  8. Drug: D01340 [KEGG MEDICUS

    Full Text Available D01340 Drug Naloxone ... hydrochloride (JP16/USP); Narcan (TN) C19H21NO4. HCl 363.1237 363.8353 D013 ... ents 221 Respiratory stimulants 2219 Others D01340 Naloxone ... hydrochloride (JP16/USP) Anatomical Therapeutic Ch ... OTHER THERAPEUTIC PRODUCTS V03AB Antidotes V03AB15 Naloxone ... D01340 Naloxone ... hydrochloride (JP16/USP) USP drug ...

  9. Crystal structure of 5-chloro-3-cyclohexylsulfinyl-2,4,6-trimethyl-1-benzofuran

    Hong Dae Choi; Uk Lee


    In the title compound, C17H21ClO2S, the cyclohexyl ring adopts a chair conformation with the C—S bond in an equatorial orientation. In the crystal, molecules are linked by C—H...O and C—H...π hydrogen bonds and a Cl...π [3.594 (2) Å] contact into chains along the a-axis direction.

  10. 3,5-Dimeth­oxy-2-[(4-propyl­phen­yl)imino­meth­yl]phenol

    Şahin, Zarife Sibel; Ağar, Ayşen Alaman; Erşahin, Ferda; Işık, Şamil


    The title compound, C18H21NO3, crystallizes in the phenol–imine tautomeric form, with the H atom attached to oxygen rather than on nitro­gen. This H atom is involved in a strong intra­molecular O—H⋯N hydrogen bond. A C—H⋯π inter­action is also present. The dihedral angle between the aromatic rings is 12.23 (7)°.

  11. Crystal structure of 5-chloro-3-cyclo­hexyl­sulfinyl-2,4,6-trimethyl-1-benzo­furan

    Choi, Hong Dae; Lee, Uk


    In the title compound, C17H21ClO2S, the cyclo­hexyl ring adopts a chair conformation with the C—S bond in an equatorial orientation. In the crystal, mol­ecules are linked by C—H⋯O and C—H⋯π hydrogen bonds and a Cl⋯π [3.594 (2) Å] contact into chains along the a-axis direction.

  12. Crystal structure of 5-chloro-3-cyclohexylsulfinyl-2,4,6-trimethyl-1-benzofuran

    Hong Dae Choi


    Full Text Available In the title compound, C17H21ClO2S, the cyclohexyl ring adopts a chair conformation with the C—S bond in an equatorial orientation. In the crystal, molecules are linked by C—H...O and C—H...π hydrogen bonds and a Cl...π [3.594 (2 Å] contact into chains along the a-axis direction.

  13. Heat resistance of Fe-Al intermetallics in the context of selected heat-resistant and hihg-temperature creep resistant steels

    P. Baranowski


    Full Text Available Results are hereby presented of heat-resistance tests of two Fe3Al and FeAl intermetallic phase-based alloys in the context of St41k-typeboiler steel and 50H21G9N4 high-temperature creep resistant steel. It has been ascertained that heat resistance of the 50H21G9N4 steeland of the Fe3Al and FeAl intermetallic phase-based alloys significantly exceeds that of the boiler steel tested in the air atmosphere and the atmosphere of a flue gas with CO, CO2, SiO2 content alike. Improvement of these properties depends of exposure conditions. The largest differences have been observed when the tests were carried out in temperature 1023 K and in the flue gas atmosphere. The differences have been more and more noticeable as the exposition duration extended. A tendency has been also recorded of smaller mass decrements of the Fe3Al and FeAl intermetallic phase-based alloys as compared to the 50H21G9N4 steel.

  14. 3-(4-Hexyloxyphenyl-1,2,4-triazolo[3,4-b]benzothiazole

    Dieter Schollmeyer


    Full Text Available The title compound, C20H21N3OS, was prepared by Huisgen reaction of 5-(4-hexyloxyphenyltetrazole and chlorobenzothiazole. The essentially planar benzothiazolotriazole framework [maximum deviation from the mean plane of 0.077 (1 Å for the bridgehead N atom] and the phenyl ring form a dihedral angle of 53.34 (5°. The hexyloxy chain adopts a gauche–all-anti conformation. The intracentroid separation of 3.7258 (8 Å between the triazole and benzene rings is the closest contact between individual molecules in the crystal.

  15. rac-Dimethyl 2-(tert-butylamino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3,4-dicarboxylate

    S. Antony Inglebert


    Full Text Available The title compound, C20H21NO7, is asymmetric with a chiral centre located in the pyran ring and crystallizes as a racemate. The molecular framework is somewhat bent; the coumarin moiety and the pyran ring are inclined by 7.85 (5°. The molecular structure is characterized by an intramolecular N—H...O hydrogen bond, which generates an S(6 ring motif, and the crystal packing is stabilized by intermolecular C—H...O hydrogen bonds. The 3-carboxylate O atom is involved in both of them, having a bifurcated character.

  16. (S-Methyl 2-benzamido-3-(3,4-dimethoxyphenylpropanoate

    Tricia Naicker


    Full Text Available The dimethoxypbenzene ring in the title compound, C19H21NO5, is gauche to the amide group and anti to the ester group. The chirality was confirmed to be S from two-dimensional NMR spectroscopy. In the crystal, N—H...O and C—H...O hydrogen bonds and several short-contact interactions (2.07–3.45 Å create chains parallel to [110]. The phenyl ring is disordered over two orientations in a 0.54 (2:0.46 (2 ratio.

  17. Diethyl [(4-nitrobenzamido(phenylmethyl]phosphonate

    Jing-Wei Chen


    Full Text Available In the title compound, C18H21N2O6P, the dihedral angle between the benzene and phenyl rings is 85.1 (2°. In the crystal, molecules are linked via pairs of N—H...O(=P hydrogen bonds, forming inversion dimers with graph-set notation R22(10. One of the ethyl groups is disordered over two sets of sites, with occupancies 0.746 (11 and 0.254 (11.

  18. Crystal structure of diethyl [(4-nitrophenylamino(2-hydroxyphenylmethyl]phosphonate methanol monosolvate

    QingMing Wang


    Full Text Available In the title compound, C17H21N2O6P·CH3OH, the planes of the 4-nitroaniline and 2-hydroxyphenyl groups form a dihedral angle of 84.04 (8°. The P atom exhibits tetrahedral geometry involving two O-ethyl groups, a Cα atom and a double-bonded O atom. In the crystal, O—H...O, N—H...O and C—H...O hydrogen bonds link the α-aminophosphonic acid and methanol molecules into chains that propagate parallel to the a axis.

  19. Crystal structure of 5-[4-(diethylaminobenzylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione

    Egija Stepina


    Full Text Available The title compound, C17H21NO4, consists of substituted Meldrum's acid with a [4-(diethylaminophenyl]methylidene fragment attached to the fifth position. The heterocycle assumes a distorted boat conformation. The planar part of heterocycle is almost coplanar with the benzene ring due to the presence of a long conjugated system in the molecule. This leads to the formation of C—H...O-type intramolecular contacts. As a result of the absence of hydrogen-bond donors in the structure, the crystal packing is controlled by van der Waals forces and weak C—H...O interactions, which associate the molecules into inversion dimers.

  20. La misura della pressione fiscale in rapporto al prodotto interno lordo in luogo del prodotto interno netto:un capitolo dell'illusione fiscale

    Francesco Forte


    Full Text Available The present paper calls attention on a major macroeconomic fiscal illusion: that arising fram the current official practice of expressing the main fiscal indicators and particularly tax burden as percentage of GDP rather than NDPF (Net Domestic Product at Factor Costs. This methodology causes a systematic undervaluation af the tax burden, by something between 25% (Sweden and Austria and 15% (Switzerland. Correctly measured, tax bur­den in most European countries is much abave 50% and in the Nordic coun­tries above 65% or close to it!  JEL Codes: H20, H21Keywords:

  1. 4-[(4-Methylbenzenesulfonamidomethyl]cyclohexanecarboxylic acid

    Muhammad Ashfaq


    Full Text Available The title compound, C15H21NO4S, crystallized with two independent molecules in the asymmetric unit in which the dihedral angles between the mean planes of the benzene and cyclohexane rings are 78.3 (2 and 67.6 (2°. The substituents of the cyclohexyl rings are in equatorial orientations. In the crystal, both molecules form R22(6 carboxylic acid inversion dimers via pairs of O—H...O hydrogen bonds. Further N—H...O and C—H...O interactions generate a three-dimensional network.

  2. N-(2-Allyl-4-ethoxy-2H-indazol-5-yl-4-methylbenzenesulfonamide

    Hakima Chicha


    Full Text Available The indazole ring system of the title compound, C19H21N3O3S, is almost planar (r.m.s. deviation = 0.0192 Å and forms dihedral angles of 77.99 (15 and 83.9 (3° with the benzene ring and allyl group, respectively. In the crystal, centrosymmetrically related molecules are connected by pairs of N—H...O hydrogen bonds into dimers, which are further linked by C—H...O hydrogen bonds, forming columns parallel to the b axis.

  3. Drug: D07473 [KEGG MEDICUS

    Full Text Available D07473 Drug Atomoxetine (INN); Tomoxetine C17H21NO 255.1623 255.3547 D07473.gif Ant...TROPICS N06BA Centrally acting sympathomimetics N06BA09 Atomoxetine D07473 Atomoxetine (INN) USP drug classi...ty Disorder Agents, Non- amphetamines Atomoxetine D07473 Atomoxetine (INN) Target-based classification of dr...ugs [BR:br08310] Transporters Solute carrier family SLC6 SLC6A2 (noradrenalin transporter) [HSA:6530] [KO:K05035] Atom...oxetine [ATC:N06BA09] D07473 Atomoxetine (INN) CAS: 83015-26-3 PubChem:

  4. 5-(Anthracen-9-yl-3-(4-nitrophenyl-1-phenyl-4,5-dihydro-1H-pyrazole

    Bao-Li Dong


    Full Text Available In the title compound, C29H21N3O2, the five-membered pyrazoline ring is nearly planar, the maximum deviation being 0.037 (3 Å. The anthracene ring system is approximately perpendicular to the central pyrazoline ring, making a dihedral angle of 86.55 (16°, whereas the two attached benzene rings are oriented at smaller dihedral angles of 12.9 (2 and 14.7 (2°with respect to the pyrazoline ring. An intramolecular C—H...N hydrogen bond is observed.

  5. Acoustooptic Diffraction in Borate Crystals

    Martynyuk-Lototska, I; Krupych, O; Adamiv, V; Smirnov, Ye; Vlokh, R


    The efficiency of acoustooptic (AO) diffraction in a-BaB2O4 and Li2B4O7 crystals is studied experimentally. The crystals are shown to be quite good AO materials. The efficiency of AO diffraction in a-BaB2O4 reaches h=30% at the electric signal power of P=0.7W for the transverse acoustic wave and 15% at the power of P=0.56W for the longitudinal wave. The same parameter for Li2B4O7 reaches h=21% at P=0,81W for the longitudinal acoustic wave.

  6. Gliclazide impurity F: N-[(perhydro­cyclo­penta­[c]pyrrol-2-yl)amino­carbon­yl]-o-toluene­sulfonamide

    Di Wu; Xueyuan Wang; Dongying Pang; Wei Su; Yan Sun


    The title compound, C15H21N3O3S, is known to be an impurity of gliclazide [systematic name: N-(hexahydro-1H-cyclopenta[c]pyrrol-2-ylcarbamoyl)-4-methylbenzenesulfonamide], a sulfonylurea antidiabetic drug. Gliclazide has a p-tolyl group substituting the sulfonamide functionality, while the title molecule contains an o-tolyl group. Both five-membered fused rings adopt envelope conformations. In the crystal, N—H...O hydrogen bonds are formed between HN(C=O)NH groups, building centrosy...

  7. Gliclazide impurity F: N-[(perhydrocyclopenta[c]pyrrol-2-ylaminocarbonyl]-o-toluenesulfonamide

    Di Wu


    Full Text Available The title compound, C15H21N3O3S, is known to be an impurity of gliclazide [systematic name: N-(hexahydro-1H-cyclopenta[c]pyrrol-2-ylcarbamoyl-4-methylbenzenesulfonamide], a sulfonylurea antidiabetic drug. Gliclazide has a p-tolyl group substituting the sulfonamide functionality, while the title molecule contains an o-tolyl group. Both five-membered fused rings adopt envelope conformations. In the crystal, N—H...O hydrogen bonds are formed between HN(C=ONH groups, building centrosymmetric dimers. These dimers are further linked through N—H...O(sulfonyl contacts, forming chains in [100].

  8. Ethyl 2-(4-bromophenyl-1-[3-(1H-imidazol-1-ylpropyl]-1H-benzimidazole-5-carboxylate monohydrate

    Yeong Keng Yoon


    Full Text Available In the title compound, C22H21BrN4O2·H2O, the two pyrazole rings are essentially planar [maximum deviations 0.002 (1 and 0.002 (1 Å], and form a dihedral angle of 73.46 (9°. The dihedral angle between the benzene rings is 29.33 (7°. In the crystal, molecules are connected via C—H...O and O—H...N hydrogen bonds, forming layers in the ab plane.

  9. Ceramics based on titanium nitride and silicon nitride sintered by SPS-method

    Sivkov, A. A.; Gerasimov, D. Yu; Evdokimov, A. A.


    The dependences of the microstructure and physical and mechanical properties of ceramic mixtures Si3N4/TiN in the full range of mass ratios of the components. Was also investigated directly, and the process of sintering occurring during a physical or chemical processes, in particular, has been obtained and the hardness of the material density on the ratio of the conductive titanium nitride phase and a silicon nitride insulating phase with values above and below the percolation threshold. Also obtained was pure ceramics based on titanium nitride with high physical-mechanical characteristics (H = 21.5 GPa).

  10. Crystal structure of 1-(2,4-dimethylphenyl-2-(4-trimethylsilyl-1H-1,2,3-triazol-1-ylethanone

    G. B. Venkatesh


    Full Text Available The asymmetric unit of the title compound, C15H21N3OSi, contains two molecules with similar conformations (r.m.s. overlay fit for the 20 non-H atoms = 0.163 Å. The dihedral angles between the planes of the 1,2,3-triazole and 2,4-dimethylbenzene rings are 27.0 (3 and 19.5 (3°. In the crystal, molecules are linked by very weak C—H...O and C—H...N hydrogen bonds to generate [100] chains. The chains are cross-linked by C—H...π interactions.

  11. Dynamic response of carbon nanotube field-effect transistors analyzed by S-parameters measurement

    Carbon nanotube field-effect transistors (CN-FET) with a metallic back gate have been fabricated. By assembling a number of CNs in parallel, driving currents in the mA range have been obtained. The dynamic response of the CN-FETs has been investigated through S-parameters measurements. A current gain (|H 21|2) cut-off frequency (f t) of 8 GHz, and a maximum stable gain (MSG) value of 10 dB at 1 GHz have been obtained. The extraction of an equivalent circuit is proposed

  12. 2,6-Bis(4-methoxyphenyl-4-phenylpyridine

    Xiaoning Dong


    Full Text Available In the title compound, C25H21NO2, which was synthesized by the condensation of 2,6-bis(4-methoxyphenyl-4-phenylpyridinium tetrafluoroborate with ammonia under microwave irradiation and solvent-free conditions, the angles between the central pyridine ring and the three benzene rings are 22.3 (2, 35.3 (2 and 19.8 (2°. In the crystal, intermolecular C—H...π hydrogen-bond interactions link the molecules.

  13. Drug: D01147 [KEGG MEDICUS

    Full Text Available D01147 Drug Nadifloxacin (JAN/INN); NDFX; Acuatim (TN) C19H21FN2O4 360.1485 360.3794 D01147.gif Antibac...vidual organs 26 Epidermides 263 Suppurative dermatosis agents 2639 Others D01147 Nadiflo...xacin (JAN/INN) CAS: 124858-35-1 PubChem: 7848210 LigandBox: D01147 NIKKAJI: J282.9...terial Therapeutic category: 2639 Fluoroquinolones DNA gyrase inhibitor [KO:K02469 K02470]; topoisomerase IV in...hibitor [KO:K02621 K02622] Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting indi

  14. Drug: D02182 [KEGG MEDICUS

    Full Text Available D02182 Drug Cocaine hydrochloride (JP16/USP); Cocaine hydrochloride (TN) C17H21NO4....ker [HSA:6335] [KO:K04841] hsa04726(6532) Serotonergic synapse hsa04728(6323+6531) Dopaminergic synapse hsa05030(6531) Cocai...c category of drugs in Japan [BR:br08301] 8 Narcotics 81 Alkaloidal narcotics 812 Coca alkaloids 8121 Coca...ines D02182 Cocaine hydrochloride (JP16/USP) Anatomical Therapeutic Chemical (ATC) ...classification [BR:br08303] N NERVOUS SYSTEM N01 ANESTHETICS N01B ANESTHETICS, LOCAL N01BC Esters of benzoic acid N01BC01 Cocai

  15. Drug: D08421 [KEGG MEDICUS

    Full Text Available D08421 Drug Procainamide (INN) C13H21N3O 235.1685 235.3253 D08421.gif Antiarrhythmi... CLASS I AND III C01BA Antiarrhythmics, class Ia C01BA02 Procainamide D08421 Procainamide (INN) USP drug cla...ssification [BR:br08302] Cardiovascular Agents Antiarrhythmics Procainamide D08421 Procainamide (INN) Target...a, NaV1.x voltage-gated sodium channel (SCN1A) [HSA:6323] [KO:K04833] Procainamid...e [ATC:C01BA02] D08421 Procainamide (INN) voltage-gated sodium channel (SCN2A) [HSA:6326] [KO:K04834] Procai

  16. Drug: D00110 [KEGG MEDICUS

    Full Text Available D00110 Drug Cocaine (USP); Cocaine (TN) C17H21NO4 303.1471 303.3529 D00110.gif Eryt...:K04841] hsa04726(6532) Serotonergic synapse hsa04728(6323+6531) Dopaminergic synapse hsa05030(6531) Cocaine... Sodium channel blocking drugs map07234 Neurotransmitter transporter inhibitors map05030 Cocaine addiction A... N01 ANESTHETICS N01B ANESTHETICS, LOCAL N01BC Esters of benzoic acid N01BC01 Cocaine D00110 Cocaine (USP) R... RESPIRATORY SYSTEM R02 THROAT PREPARATIONS R02A THROAT PREPARATIONS R02AD Anesthetics, local R02AD03 Cocaine D00110 Cocai

  17. Drug: D01830 [KEGG MEDICUS

    Full Text Available D01830 Drug Arotinolol hydrochloride (JP16); Almarl (TN) C15H21N3O2S3. HCl 407.0563... 408.0021 D01830.gif Antihypertensive Therapeutic category: 2123 alpha1-adrenergic receptor antagonist [HSA:...146 147 148] [KO:K04137 K04136 K04135]; beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]; beta2-adr...energic receptor antagonist [HSA:154] [KO:K04142]; beta3-adrenergic receptor ant...48+153+154+155) Neuroactive ligand-receptor interaction hsa04261(146+147+148+153+154) Adrenergic signaling i

  18. Drug: D04905 [KEGG MEDICUS

    Full Text Available D04905 Drug Memantine hydrochloride (JAN/USAN); Namenda (TN); Memary (TN) C12H21N. ...-aspartic acid receptor antagonists Therapeutic category of drugs in Japan [BR:br08301] 1 Agents affecting n...ervous system and sensory organs 11 Agents affecting central nervous system 119 Miscellaneous 1190 Miscellan...TC) classification [BR:br08303] N NERVOUS SYSTEM N06 PSYCHOANALEPTICS N06D ANTI-DEMENTIA DRUGS N06DX Other anti-dementia dr...ugs N06DX01 Memantine D04905 Memantine hydrochloride (JAN/USAN) USP drug classification [BR:b

  19. Drug: D02147 [KEGG MEDICUS

    Full Text Available D02147 Drug Albuterol (USP); Salbutamol; Proventil (TN) C13H21NO3 239.1521 239.3107... D02147.gif Bronchodilator [DS:H00079] ATC code: R03AC02 R03CC02 beta2-adrenergic receptor agonist [HSA:154]...3A ADRENERGICS, INHALANTS R03AC Selective beta-2-adrenoreceptor agonists R03AC02 Salbutamol D02147 Albuterol... (USP); Salbutamol R03C ADRENERGICS FOR SYSTEMIC USE R03CC Selective beta-2-adren...oreceptor agonists R03CC02 Salbutamol D02147 Albuterol (USP); Salbutamol USP drug classification [BR:br08302

  20. Drug: D07465 [KEGG MEDICUS

    Full Text Available D07465 Drug Arotinolol (INN) C15H21N3O2S3 371.0796 371.5411 D07465.gif Antiarrhythmic alpha1-adr...energic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]; beta1-adrenergic recep...tor antagonist [HSA:153] [KO:K04141]; beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142]; beta3-adre...61(146+147+148+153+154) Adrenergic signaling in cardiomyocytes hsa04270(146+147+148) Vascular smooth muscle ...contraction hsa04970(146+147+148+153+154+155) Salivary secretion map07214 beta-Adr

  1. 红曲红色素的光褪色研究%The Study on Mechanism of Photobleaching for Red Monascus pigment




  2. Drug: D02101 [KEGG MEDICUS

    Full Text Available D02101 Drug Codeine phosphate hydrate (JP16); Codeine phosphate (USP); Codeine (TN)... (C18H21NO3)2. 2H3PO4. H2O 812.2686 812.7341 D02101.gif Antitussive; Analgesic [narcotic] Therapeutic catego...ssives and expectorants 2242 Codeines D02101 Codeine phosphate hydrate (JP16); Codeine phosphate (USP) 8 Nar...cotics 81 Alkaloidal narcotics 811 Opium alkaloids 8115 Codeines D02101 Codeine phosphate hydrate (JP16); Co... EXPECTORANTS R05DA Opium alkaloids and derivatives R05DA04 Codeine D02101 Codeine phosphate hydrate (JP16);

  3. 1-Carboxymethyl-1′-carboxylatomethyl-3,3′-[p-phenylenebis(oxymethylene]dipyridinium bromide dihydrate

    Wei-Cheng Pan


    Full Text Available In the crystal structure of the title salt, C22H21N2O6+·Br−·2H2O, pairs of betaine molecules are bridged by protons (the bridging proton is disordered, forming strong and symmetrical O—H...O hydrogen bonds, leading to an infinite chain along the b axis. The water molecules are linked to the betaine molecule and the bromide ion through O—H...O and O—H...Br interactions. The central ring, located on an inversion centre, makes dihedral angles of 1.2 (2° with the outer rings. One of the carboxylic acid groups is deprotonated.

  4. (2E-1-Phenyl-2-[1-(2-phenylprop-2-en-1-ylpyrrolidin-2-ylidene]ethanone

    Lee G. Madeley


    Full Text Available The title compound, C21H21NO, is a vinylogous amide (enaminone produced by reaction of 1-(2-phenylprop-2-en-1-ylpyrrolidine-2-thione with phenacyl bromide. In the molecule, the phenyl rings are twisted from the mean plane of the pyrrolidine ring by 11.2 (1 and 67.3 (1°. In the crystal, weak C—H...O hydrogen bonds link the molecules related by translation along the b axis into chains.

  5. Characterization of seed oils from different varieties of watermelon [Citrullus lanatus (Thunb.)] from Pakistan

    Mahmood, Z; Shahid, S. A.; Anwar, F.; Raziq, S.; Nadeem, R.


    This paper reports the physicochemical characteristics of the seed oils from different varieties of watermelon (Citrullus lanatus) cultivated in Pakistan, namely Sugar Baby, Q-F-12, D-W-H-21 and Red Circle-1885. The oil and crude protein contents from watermelon seeds, within the range of 28.25 to 35.65% and 20.50 to 35.00%, respectively, varied significantly (p < 0.05) among the varieties tested. The levels of moisture, ash, and crude fiber in the seeds tested were found to be 2.16-3.24%, 1....

  6. (2Z)-1-(5-Hy­droxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-3-(4-methyl­anilino)­but-2-en-1-one

    Asiri, Abdullah M.; Al-Youbi, Abdulrahman O.; Ng, Seik Weng; Tiekink, Edward R. T.


    A twist is evident in the title compound, C21H21N3O2, the dihedral angle between the terminal six-membered rings being 29.46 (10)°; the linked five- and six-membered rings are coplanar [1.30 (11)°]. The carbonyl O atom accepts intra­molecular hydrogen bonds from the adjacent hy­droxy and amine groups. The three-dimensional crystal packing is achieved through C—H⋯π inter­actions.

  7. Diazido{(S-1-phenyl-N,N-bis[(2-pyridylmethyl]ethanamine}copper(II

    Sankara Rao Rowthu


    Full Text Available In the title compound, [Cu(N32(C20H21N3], the CuII ion is coordinated by the three N atoms of the (S-1-phenyl-N,N-bis[(2-pyridylmethyl]ethanamine ligand and two N atoms from two azide anions, resulting in a distorted square-pyramidal environment. A weak intermolecular C—H...N hydrogen-bonding interaction between one pyridine group of the ligand and an azide N atom of an adjacent complex unit gives a one-dimensional chain structure parallel to the c axis.

  8. N-(2-Chlorophenyl-2-({5-[4-(methylsulfanylbenzyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanylacetamide

    Hoong-Kun Fun


    Full Text Available In the title molecule, C24H21ClN4OS2, the central 1,2,4-triazole ring forms dihedral angles of 89.05 (9, 86.66 (9 and 82.70 (10° with the chloro-substituted benzene ring, the methylsulfanyl-substituted benzene ring and the phenyl ring, respectively. In the crystal, molecules are linked into sheets parallel to (100 by intermolecular N—H...N and weak C—H...O hydrogen bonds.

  9. Drug: D07563 [KEGG MEDICUS

    Full Text Available D07563 Drug Alizapride hydrochloride; Plitican (TN) C16H21N5O2. HCl 351.1462 351.83...ETABOLISM A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS A03F PROPULSIVES A03FA Propulsives A03FA05 Alizapride D07563 Alizapride...receptors Rhodopsin family Dopamine dopamine D2-receptor [HSA:1813] [KO:K04145] Alizapride... [ATC:A03FA05] D07563 Alizapride hydrochloride CAS: 59338-87-3 PubChem: 51091884 LigandBox: D07563

  10. Drug: D02126 [KEGG MEDICUS

    Full Text Available D02126 Drug Primaquine phosphate (USP); Primaquine (TN) C15H21N3O. 2H3PO4 455.1223 ...ICIDES AND REPELLENTS P01 ANTIPROTOZOALS P01B ANTIMALARIALS P01BA Aminoquinolines P01BA03 D02126 Primaquine phosphate (USP) USP drug classification [BR:br08302] Antiparasitics Antiprotozoals D02126 Primaquine phosphate (USP) Antiinfectives [BR:br08307] Antiparasitics Antmala...rials Others Aminoquinolines Primaquine [ATC:P01BA03] D02126 Primaquine phosphate

  11. Drug: D08420 [KEGG MEDICUS

    Full Text Available D08420 Drug Primaquine (INN); Kanaprim (TN) C15H21N3O 259.1685 259.3467 D08420.gif ...oquinolines P01BA03 Primaquine D08420 Primaquine (INN) USP drug classification [BR:br08302] Antiparasitics Antiprotozoals D08420 Primaquine (INN) Antiinfectives [BR:br08307] Antiparasitics Antmalarials Oth...ers Aminoquinolines Primaquine [ATC:P01BA03] D08420 Primaquine (INN) CAS: 90-34-6...CTS, INSECTICIDES AND REPELLENTS P01 ANTIPROTOZOALS P01B ANTIMALARIALS P01BA Amin

  12. ALMA Observations of Orion Source I at 350 and 660 GHz

    Plambeck, R L


    Orion Source I ('SrcI') is the protostar at the center of the Kleinmann-Low Nebula. ALMA observations of SrcI at 350 and 660 GHz failed to detect the H26$\\alpha$ and H21$\\alpha$ recombination lines, ruling out the possibility that SrcI is a hypercompact HII region. The deconvolved size of the continuum source is approximately 0.23 x 0.05" (100 x 20 AU); it is interpreted as a disk viewed almost edge-on. The continuum flux density is proportional to $\

  13. 1-[(6-Chloro-3-pyridylmethyl]-N-(4-ethoxyphenyl-3-phenyl-1H-pyrazole-5-carboxamide

    Zheng Tang


    Full Text Available In the title compound, C24H21ClN4O2, the pyrazole ring makes dihedral angles of 7.70 (11, 89.17 (11 and 40.68 (11° with the phenyl, pyridine and ethoxyphenyl rings, respectively. There are some intramolecular C—H...O and C—H...π bonds giving rigidity to the molecule, while weak intermolecular N—H...N and C—H...π hydrogen bonds link the molecules into a two-dimensional structure.

  14. Dicty_cDB: AFI627 [Dicty_cDB

    Full Text Available 19D15 5' sequence, mRNA sequence. 38 0.12 2 AI490786 |AI490786.1 EST241494 tomato shoot, Cornell Lycopersico...e, mRNA sequence. 38 0.12 2 AI773934 |AI773934.1 EST255034 tomato resistant, Cornell Lycopersicon esculentum...11252.5 Drosophila melanogaster clone BACR23H21, complete sequence. 42 0.058 6 AI484136 |AI484136.1 EST248943 tomato resistant, Corne...ll Lycopersicon esculentum cDNA clone cLER1C5, mRNA sequence. 38 0.12 2 BG128254 |B

  15. [(4-Methylbenzylbis(pyridin-2-ylmethylamine-κ3N,N′,N′′]bis(thiocyanato-κScopper(II dichloromethane hemisolvate

    Yan Qi


    Full Text Available The title compound, [Cu(NCS2(C20H21N3]·0.5CH2Cl2, crystallized with two independent complex molecules (A and B in the asymmetric unit, accompanied by one dichloromethane solvent molecule. Each CuII atom has a square-pyramidal geometry, being coordinated by five N atoms, three from the (4-methylbenzylbis(pyridin-2-ylmethylamine ligand and two from the thiocyanate ligands. In the crystal, the B molecules are linked via C—H...S interactions, forming chains propagating along [100].

  16. Drug: D00652 [KEGG MEDICUS

    Full Text Available D00652 Drug Brinzolamide (JAN/USP/INN); Azopt (TN) C12H21N3O5S3 383.0643 383.5072 D...ents affecting sensory organs 131 Ophthalmic agents 1319 Others D00652 Brinzolamide (JAN/USP/INN) Anatomical...HALMOLOGICALS S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS S01EC Carbonic anhydrase inhibitors S01EC04 Brinzolamide D00652 Brinzolamide...amide D00652 Brinzolamide (JAN/USP/INN) Target-based cla...67 768 771 377677 23632 100996556] [KO:K01672] Brinzolamide [ATC:S01EC04] D00652 Brinzolamide (JAN/USP/INN)

  17. Crystal structure of pencycuron

    Gihaeng Kang; Jineun Kim; Eunjin Kwon; Tae Ho Kim


    In the title compound [systematic name: 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea], C19H21ClN2O, which is a urea fungicide, the cyclopentyl ring adopts an envelope conformation, with one of the methylene C atoms adjacent to the C atom bonding to the N atom as the flap. The dihedral angles between the mean planes of the central cyclopentyl ring (all atoms) and the chlorobenzyl and phenyl rings are 77.96 (6) and 57.77 (7)°, respectively. In the crystal, N—H...O hydrogen bonds link adjacent ...

  18. Development of The Viking Speech Scale to classify the speech of children with cerebral palsy.

    Pennington, Lindsay; Virella, Daniel; Mjøen, Tone; da Graça Andrada, Maria; Murray, Janice; Colver, Allan; Himmelmann, Kate; Rackauskaite, Gija; Greitane, Andra; Prasauskiene, Audrone; Andersen, Guro; de la Cruz, Javier


    Surveillance registers monitor the prevalence of cerebral palsy and the severity of resulting impairments across time and place. The motor disorders of cerebral palsy can affect children's speech production and limit their intelligibility. We describe the development of a scale to classify children's speech performance for use in cerebral palsy surveillance registers, and its reliability across raters and across time. Speech and language therapists, other healthcare professionals and parents classified the speech of 139 children with cerebral palsy (85 boys, 54 girls; mean age 6.03 years, SD 1.09) from observation and previous knowledge of the children. Another group of health professionals rated children's speech from information in their medical notes. With the exception of parents, raters reclassified children's speech at least four weeks after their initial classification. Raters were asked to rate how easy the scale was to use and how well the scale described the child's speech production using Likert scales. Inter-rater reliability was moderate to substantial (k>.58 for all comparisons). Test-retest reliability was substantial to almost perfect for all groups (k>.68). Over 74% of raters found the scale easy or very easy to use; 66% of parents and over 70% of health care professionals judged the scale to describe children's speech well or very well. We conclude that the Viking Speech Scale is a reliable tool to describe the speech performance of children with cerebral palsy, which can be applied through direct observation of children or through case note review. PMID:23891732

  19. Nutritional disorder of lettuce cv. Veronica in nutrient solution with suppressed macronutrients

    Thiago Batista Firmato de Almeida


    Full Text Available Lettuce is the most popular of the leafy vegetables. It is known worldwide and its consumption occurs mainly in the natural form. The objective was to evaluate the effect of macronutrient omission on the growth and nutritional status of the lettuce cv. Veronica, and to describe the visual symptoms of nutritional deficiency. The treatments complete consisted of the solution and the individual omission of N, P, K, Ca, Mg and S, under a completely randomized design with three replications. Plants were grown in Hoagland & Arnon, in pots (8L. At 56 days after transplant we evaluated plant height, leaf number, leaf area, SPAD index, dry matter of shoots, roots and whole plant, levels of macronutrients in shoots and roots, and the nature of nutritional disorders. The omission of nutrients affected the growth variables. The nutrients found in lettuce plants from nutrient solution and the complete omission in the shoot were, respectively, N= 23.2 to 9.5, P= 5.4 to 1.3, K= 58,9 to 3.2, Ca= 12.1 to 3.6, Mg= 5.5 to 0.7 and S= 3.2 to The omission of macronutrients caused quality losses, since it affected the nutrition of the vegetables and this resulted in morphological changes, reflected as symptoms of deficiency for each nutrient.

  20. Studies on the relationship between lectin binding carbohydrates and different strains of Leishmania from the New World

    J. Schottelius


    Full Text Available The culture forms of L. mexicana pifanoi (LRC L-90, L. mexicana mexicana (LRC L-94, M-379; L. braziliensis braziliensis (LRC L-77, L-1, M-2903, H-LSS and L. mexicana amazonensis (H-JMMO, M-JOF, H-21, H-PLL,M-1696 were tested with the following lectins: Canavalia ensiformis, Ricinus communis-120, Axinella polypoides, Phaseolus vulgaris, Evonymus europaeus, lotus tetragonolobus, Dolichos biflorus, Aaptos papillata II, Laburnum alpinum, Ulex europaeus, Arachis hypogaea and Soja hispida. All examined strains of Leishmania were agglutinated by C. ensiformis, R. communis-120 and A. popypoides. No agglutination reactions were observed with P. vulgaris, D.biflorus, A. papillata II, E. europaeus and L. tetragonolobus. Only L. m. pifanoi and the L. m. amazonensis strains H-JMMO and MJOF showed agglutination reactions with S. hispida, U. europaeus, L. alpinum and A. hypogaea, while L. m. mexicana (LRC L-94; M-379 strains, L. b. braziliensis H. LSS, LRC L-77; L-1; M-2903 and the L. m. amazonensis strains, H-PLL, H-21, M-1696 showed no agglutination reactions with these four lectins.

  1. Comparison of eight different agars for the recovery of clinically relevant non-O157 Shiga toxin-producing Escherichia coli from baby spinach, cilantro, alfalfa sprouts and raw milk.

    Kase, Julie A; Maounounen-Laasri, Anna; Son, Insook; Lin, Andrew; Hammack, Thomas S


    The FDA Bacteriological Analytical Manual (BAM) Chapter 4a recommends several agars for isolating non-O157 Shiga toxin-producing Escherichia coli (STEC); not all have been thoroughly tested for recovering STECs from food. Using E. coli strains representing ten clinically relevant O serogroups (O26, O45, O91, O103, O104, O111, O113, O121, O128, O145) in artificially-contaminated fresh produce--bagged baby spinach, alfalfa sprouts, cilantro, and raw milk--we evaluated the performance of 8 different agars. Performance was highly dependent upon strain used and the presence of inhibitors, but not necessarily dependent on food matrix. Tellurite resistant-negative strains, O91:-, O103:H6, O104:H21, O113:H21, and O128, grew poorly on CHROMagar STEC, Rainbow agar O157, and a modified Rainbow O157 (mRB) agar. Although adding washed sheep's blood to CHROMagar STEC and mRB agars improved overall performance; however, this also reversed the inhibition of non-target bacteria provided by original formulations. Variable colony coloration made selecting colonies from Rainbow agar O157 and mRB agars difficult. Study results support a strategy using inclusive agars (e.g. L-EMB, SHIBAM) in combination with selective agars (R & F E. coli O157:H7, CHROMagar STEC) to allow for recovery of the most STECs while increasing the probability of recovering STEC in high bacterial count matrices. PMID:25475297

  2. Triadophilia: A Special Corner in the Landscape

    Candelas, Philip; He, Yang-Hui; Szendroi, Balazs


    It is well known that there are a great many apparently consistent vacua of string theory. We draw attention to the fact that there appear to be very few Calabi--Yau manifolds with the Hodge numbers h^{11} and h^{21} both small. Of these, the case (h^{11}, h^{21})=(3,3) corresponds to a manifold on which a three generation heterotic model has recently been constructed. We point out also that there is a very close relation between this manifold and several familiar manifolds including the `three-generation' manifolds with \\chi=-6 that were found by Tian and Yau, and by Schimmrigk, during early investigations. It is an intriguing possibility that we may live in a naturally defined corner of the landscape. The location of these three generation models with respect to a corner of the landscape is so striking that we are led to consider the possibility of transitions between heterotic vacua. The possibility of these transitions, that we here refer to as transgressions, is an old idea that goes back to Witten. Here...

  3. Macrocyclic structures of associated complexes of lithium tetraalkyl borates

    IR spectroscopy and 7Li, 11B NMR were used to study the structure of complex associates [ButOB(OR)3]Li·mHOR (R=Bun, n-C7H15, n-C10H21, n-C13H27; m=0-2) in organic solvents (heptane, cyclohexane-d12) in the concentration range of 0.03-0.07 mol l-1 at 22 deg C. The NMR spectra show magnetic equivalence of all the 7Li and 11B nuclei in the complex associates, that unambiguously confirms their macrocyclic structure. IR spectroscopy data testify to the fact that in the alcoholic solvate Li atom transfers from a strained hexacoordinate state to a more stable tetracoordinate one due to the expansion of intramolecular cycle in each monomer of the polyassociate

  4. Irradiation-induced ordering of a disordered suspension of superheated microspheres

    The 'hot border model' of a suspension of Type-I metastable superconducting grains under irradiation is modified to incorporate heating considerations, and results in the existence of two borders h1 and h2 defined by the minimum and maximum grain volumes of the suspension, respectively. Following a sufficiently long irradiation, the true 'hot border', i.e. the region of the (T, H) phase space in which no superconducting grains exist, should lie only a distance h21 below the phase line: between the two borders, the superconducting grain population is only depleted, and ordered according to decreasing size with increasing distance from the phase line. We provide a partial experimental confirmation of this, and discuss how this modification results in an intrinsic energy calibration for device spectroscopy

  5. 5-Bromospiro[1,2-dioxane-4,4′-tricyclo[,8]undecane]-3′-ol

    Tony V. Robinson


    Full Text Available The title compound, C14H21BrO3, comprises a seven- (C7 and three six-membered (1 × O2C4 and 2 × C6 rings, and each adopts a conformation based on a chair. Stability to the molecular structure is afforded by an intramolecular O—H...Br hydrogen bond. In the crystal structure, molecules are arranged into a helical supramolecular chain along the b axis, linked by C—H...O interactions, where the O-atom acceptor is one of the dioxane O atoms. The crystal studied was found to be a racemic twin. The major component was present 94% of the time.

  6. AcEST: DK948126 [AcEST

    Full Text Available TLWFGSLAGLLIEINRLF 33 >tr|B6RRE9|B6RRE9_9CARY PSI reaction centre subunit IX OS=Heliosperma alpestre...MQDVKTYLSTAPVLATLWFGFLAGLLIEINRFF 33 >sp|Q6YXM2|PSAJ_PHYPA Photosystem I reaction center subunit IX OS=Physcomitrella paten...ris mRNA, clone: TST38A01NGRL0002_H21, 5' (585 letters) Database: uniprot_trembl.fasta 7,341,751 sequences...VK YLSTAPV+A IWF +LAGLLIEINRFF Sbjct: 1 MQYVKTYLSTAPVLAAIWFAILAGLLIEINRFF 33 TrEMBL (release 39.9) Link to BlastX Result : TrEMBL tr...|B0LP54|B0LP54_9CARY PSI reaction centre subunit IX OS=Silene ... 54 5e-06 tr

  7. Measuring Tax Efficiency

    Raimondos-Møller, Pascalis; Woodland, Alan D.


    This paper introduces an index of tax optimality thatmeasures the distance of some current tax structure from the optimal taxstructure in the presence of public goods. In doing so, we derive a [0, 1]number that reveals immediately how far the current tax configurationis from the optimal one and......, thereby, the degree of efficiency of a taxsystem. We call this number the Tax Optimality Index. We show howthe basic method can be altered in order to derive a revenue equivalentuniform tax, which measures the size of the public sector. A numericalexample is used to illustrate the method developed.......JEL Code: H21, H41.Keywords: Tax optimality index, excess burden, distance function.Authors Affiliations: Raimondos-Møller: Copenhagen Business School, CEPR,CESifo, and EPRU. Woodland: University of Sydney....

  8. A new layered iron fluorophosphate

    Amitava Choudhury


    A new iron fluorophosphate of the composition, [C6N4H21] [Fe2F2(HPO4)3][H2PO4]·2H2O, I has been prepared by the hydrothermal route. This compound contains iron fluorophosphate layers and the H2PO$_{4}^{-}$ anions are present in the interlayer space along with the protonated amine and water molecules. The compound crystallizes in the monoclinic space group 21/. ( = 13.4422(10) Å, = 9.7320(10) Å, = 18.3123(3) Å, = 92.1480 °, = 2393.92(5) Å3, = 4, = 719.92, calc = 1.997 g cm-3, 1 = 0.03 and 2 = 0.09).

  9. Dicty_cDB: Contig-U15472-1 [Dicty_cDB

    Full Text Available one biosynthesis protein ... 114 1e-23 CP000151_2867( CP000151 |pid:none) Burkholderia sp. 383 chromosome...................done Score E Sequences producing significant alignments: (bits) Value N ( BJ388348 ) Dictyostelium disc...g-17000298938509 Dog Library Canis lup... 46 4.0 1 ( EL596717 ) He_pwd_0197E11_M13R Heliconius erato pooled wing...X359575 ) GQ03201.SP6_H18 GQ032 - Shoot tip (Normalized lib... 46 4.0 1 ( EX345037 ) GQ03102.SP6_H21 GQ031 - Xylem Scraping...P001013_3988( CP001013 |pid:none) Leptothrix cholodnii SP-6, comp... 112 5e-23 CU458896_2369( CU458896 |pid:none) Mycobacterium absc

  10. Ethyl 1-[3-(1H-imidazol-1-ylpropyl]-2-(4-chlorophenyl-1H-benzo[d]imidazole-5-carboxylate dihydrate

    Yeong Keng Yoon


    Full Text Available In the title compound, C22H21ClN4O2·2H2O, the almost-planar benzimidazole ring system [maximum deviation 0.014 (1 Å] is inclined at angles of 36.32 (5 and 74.75 (7° with respect to the phenyl and imidazole rings, respectively. In the crystal structure, the water molecules are linked to the organic molecules to form a three-dimensional network via O—H...N and O—H...O hydrogen bonds. The packing is further consolidated by a pair of bifurcated C—H...O bonds, generating R12(6 loops. C—H...π interactions are also observed.

  11. Dicty_cDB: Contig-U08738-1 [Dicty_cDB

    Full Text Available 5_1( EU204935 |pid:none) Cercocebus torquatus atys Toll-lik... 34 8.4 >AC115598_29( AC115598 |pid:none) Dictyosteli...e E Sequences producing significant alignments: (bits) Value N ( AC115598 ) Dictyosteli...e: ddbj_A 92,845,959 sequences; 95,242,211,685 total letters Searching..................................................done Scor...l... 46 2.4 1 ( CZ465768 ) MCF757h21TR Human MCF7 breast cancer cell line li... 46 2.4 1 ( CW945452 ) TcB27.4_E09_SP6 Triboli...S-2004 whole ... 34 6.3 2 ( EY536327 ) CAPF9934.rev CAPF Capitella sp. I ECS-2004 whole ... 34 6.3 2 ( AC123513 ) Dictyosteli

  12. Dicty_cDB: Contig-U09858-1 [Dicty_cDB

    Full Text Available 9666_1( M19666 |pid:none) Slime mold (D.discoideum) ubiquitin ge... 48 6e-04 AY857455_1( AY857455 |pid:none) Suberites...ideum cDNA clone:ddc6n04, 3' e... 1059 0.0 1 ( AU262059 ) Dictyostelium discoideum vegetative, 3' ... 856 0.0 2 ( AU269023 ) Dictyostelium discoideum vegetative cDNA clone:VS... 684 0.0 3 (... AU269022 ) Dictyostelium discoideum vegetative cDNA clone:VS... 436 0.0 2 ( BJ327362 ) Dictyostelium disc..... 226 1e-63 2 ( AU060429 ) Dictyostelium discoideum slug cDNA, clone SLJ711. 72 3e-10 2 ( BI862953 ) rm14e07.y1 Meloidogyne arenari

  13. Studies on flower initiation of Super-Dwarf wheat under stress conditions simulating those on the Space Station, Mir

    Jiang, L.; Salisbury, F. B.; Campbell, W. F.; Carman, J. G.; Nan, R.


    Super-Dwarf wheat plants were grown in growth chambers under 12 treatments with three photoperiods (18 h, 21 h, 24 h) and four carbon dioxide (CO2) levels (360, 1,200, 3,000 and 7,000 micromoles mol-1). Carbon dioxide concentrations affected flower initiation rates of Super-Dwarf wheat. The optimum CO2 level for flower initiation and development was 1,200 micromoles mol-1. Super-optimum CO2 levels delayed flower initiation, but did not decrease final flower bud number per head. Longer photoperiods not only accelerated flower initiation rates, but also decreased deleterious effects of super-optimum CO2. Flower bud size and head length at the same developmental stage were larger under longer photoperiods, but final flower bud number was not affected by photoperiod.

  14. A novel high-performance high-frequency SOI MESFET by the damped electric field

    Orouji, Ali A.; Khayatian, Ahmad; Keshavarzi, Parviz


    In this paper, we introduce a novel silicon-on-insulator (SOI) metal-semiconductor field-effect-transistor (MESFET) using the damped electric field (DEF). The proposed structure is geometrically symmetric and compatible with common SOI CMOS fabrication processes. It has two additional oxide regions under the side gates in order to improve DC and RF characteristics of the DEF structure due to changes in the electrical potential, the electrical field distributions, and rearrangement of the charge carriers. Improvement of device performance is investigated by two-dimensional and two-carrier simulation of fundamental parameters such as breakdown voltage (VBR), drain current (ID), output power density (Pmax), transconductance (gm), gate-drain and gate-source capacitances, cut-off frequency (fT), unilateral power gain (U), current gain (h21), maximum available gain (MAG), and minimum noise figure (Fmin). The results show that proposed structure operates with higher performances in comparison with the similar conventional SOI structure.


    Abdul Hakim


    Full Text Available Assigning autonomy to regency governments in Indonesia has failed to increase regency’s economies.While it increases regency government role in planning and initiating policies, its impact oneconomic development has been insignificant. This stems from the lack of institution’s capacity inorganizing the bulk funds transfer from the central government which leads to inefficiency in resourceallocation. This paper maps these regencies based on their fiscal dependency. This paperalso applies Data Envelopment Analysis to identify the efficient and non efficient regencies in sucha way that the non efficient regencies might use the efficient ones as the benchmark to increase theirefficiency.Keywords: Autonomy, regency government, efficiencyJEL classification numbers: H21, H53, H71, H72

  16. Crystal structure of (E-2-(2-{5-[(2-acetoxyethyl(methylamino]thiophen-2-yl}vinyl-3-methylbenzothiazolium iodide monohydrate

    Xian-Shun Sun


    Full Text Available In the cation of the title hydrated salt, C19H21N2O2S2+·I−·H2O, the benzothiazolium ring system is approximately planar [maximum deviation = 0.0251 (15 Å], and it makes a small dihedral angle of 1.16 (18° with the plane of the thiophene ring. In the crystal, the cations, anions and crystalline water molecules are linked by classical O—H...O, O—H...I and weak C—H...O hydrogn bonds, forming a three-dimensional supramolecular network. π–π stacking is observed between parallel thiazole rings of adjacent cations [centroid–centroid distance = 3.5945 (16 Å].

  17. Theoretical Investigation on the Adsorption of Ag+ and Hydrated Ag+ Cations on Clean Si(111)Surface

    SHENG Yong-Li; LI Meng-Hua; WANG Zhi-Guo; LIU Yong-Jun


    In this paper,the adsorption of Ag+ and hydrated Ag+ cations on clean Si(111)surface were investigated by using cluster(Gaussian 03)and periodic(DMol3)ab initio calculations.Si(111)surface was described with cluster models(Si14H17 and Si22H21)and a four-silicon layer slab with periodic boundary conditions.The effect of basis set superposition error(BSSE)was taken into account by applying the counterpoise correction.The calculated results indicated that the binding energies between hydrated Ag+ cations and clean Si(111)surface are large,suggesting a strong interaction between hydrated Ag+ cations and the semiconductor surface.With the increase of number,water molecules form hydrogen bond network with one another and only one water molecule binds directly to the Ag+ cation.The Ag+ cation in aqueous solution will safely attach to the clean Si(111)surface.

  18. X-Ray diffraction and vibrational spectroscopic study of 2-chloro-N-{4-[3-(2,5-dimethylphenyl)-3-methylcyclobutyl] -thiazol-2-yl}-acetamide

    The title compound C18H21ClN2SO crystallizes with Z = 4 in space group P21/c. The structure of the title compound was characterized by 1H-NMR, 13C-NMR, IR and single crystal diffraction. There are an intermolecular N-H-O hydrogen bond and a C-H-π interactions in crystal packing. In addition to the molecular geometry and packing obtained from X-ray experiment, the molecular geometry and vibrational frequencies of the title compound in ground state have been calculated using density functional theory method DFT (B3LYP) with 6-31G (d, p) basis set. Calculated frequencies, bond lengths, angles and dihedral angles are in good agreement with the corresponding experimental data.

  19. Drug: D02115 [KEGG MEDICUS

    Full Text Available D02115 Drug Methotrexate sodium; Trexall (TN) C20H21N8O5. Na 476.1533 476.4211 D021...p07050 Antirheumatics - DMARDs and biological agents map04976 Bile secretion Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS L01 ANTINEOPLASTIC AGENTS L01B ANTIMETABOLITES L01BA Folic acid analogues L01BA01 Methotrexate D02115 Methotrexate sodium L04 IMMUNOSUPPRESSANTS L04A IMMUNOSUPPRESSANTS L04AX Other immunosuppressants L04AX03 Methotrexate D02115 Methotrexate sodium USP drug classification [BR:br08302] Immunological Agents Immune Suppressants Methotrexate D02115 Methotrexate sodium Target-based classification of drugs [BR:br08310] Enzymes Oxidoredu...ase [HSA:1719 200895] [KO:K00287] Methotrexate...lites Folic acid analogues Methotrexate... [ATC:L01BA01] D02115 Methotrexate sodium CAS: 15475-56-6 PubChem: 78

  20. (2Z-1-(5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl-3-(4-methoxyanilinobut-2-en-1-one

    Abdullah M. Asiri


    Full Text Available The central residue in the title compound, C21H21N3O3, is close to planar (r.m.s. deviation = 0.0753 Å for all non-H atoms from OH to NH inclusive: the hydroxy, amino and carbonyl groups all lie to the same side of the molecule (the conformation about the ethene bond is Z, facilitating the formation of intramolecular O—H...O and N—H...O hydrogen bonds that close S(6 rings. However, overall the molecule is twisted as the terminal aromatic rings are not coplanar with the central plane [dihedral angles = 20.55 (5 and 80.90 (4° for the N-bound phenyl ring and the methoxybenzene ring, respectively]. The dihedral angle between the rings is 82.14 (7°. Supramolecular layers in the ac plane mediated by C—H...π interactions are found in the crystal.

  1. N-[7-Ethoxy-1-(prop-2-en-1-yl-1H-indazol-4-yl]-4-methylbenzenesulfonamide

    Najat Abbassi


    Full Text Available In the title compound, C19H21N3O3S, the C—SO2—NH—C torsion angle is 103.72 (11°. The almost planar indazole ring [r.m.s. deviation = 0.0202 (14 Å] is twisted away from the methylbenzene ring by 76.87 (7°. The vinyl group is disordered over two orientations with site occupancies of 0.622 (10 and 0.378 (10. The S atom has a distorted tetrahedral geometry [maximum deviation: O—S—O = 119.18 (11°]. An intramolecular C—H...O hydrogen bond occurs. In the crystal, two molecules are linked about a center of inversion by pairs of N—H...O hydrogen bonds, generating a dimer. C—H...π interactions are also observed.

  2. Biochemical studies on certain biologically active nitrogenous compounds

    Certain biologically active nitrogenous compounds such as alkaloids are widely distributed in many wild and medicinal plants such as peganum harmala L. (Phycophyllaceae). However, less literature cited on the natural compounds was extracted from the aerial parts of this plant; therefore this study was conducted on harmal leaves using several solvents. Data indicated that methanol extract was the inhibitoriest effect against some pathogenic bacteria, particularly Streptococcus pyogenus. Chromatographic separation illustrated that presence of four compounds; the most active one was the third compound (3). Elementary analysis (C, H, N) revealed that the primary chemical structure of the active antibacterial compound (C3) was: C17 H21 N3 O7 S with molecular weight 411. Spectroscopic analysis proved that coninical structure was = 1- thioformyl, 8?- D glucoperanoside- Bis- 2, 3 dihydroisopyridino pyrrol. This new compound is represented as a noval ?- carboline alkaloid compound

  3. 6-Butyl-5-(4-methylphenoxy-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7(6H-one

    Hong-Mei Wang


    Full Text Available In the title compound, C21H21N5O2, the triazolopyrimidine ring system is essentially planar [maximum displacement = 0.021 (4 Å] and forms dihedral angles of 41.17 (9 and 67.99 (8° with the phenyl and benzene rings, respectively. The n-butyl side chains is disordered over two positions with an ccupancy ratio of 0.77:0.23. An intramolecular C—H...O hydrogen-bonding interaction stabilizes the molecular conformation. In the crystal, molecules are linked by intermolecular C—H...O and C—H...N hydrogen bonds into a three-dimensional network. In addition, π–π stacking interactions involving the triazole and pyrimidine rings of adjacent molecules are observed, with centroid–centroid distances of 3.545 (1 Å.

  4. Synthesis, structural, and spectroscopic (FT-IR, NMR, and UV) Characterization of 1-(Cyclohexylmethyl)-2-(pyridin-2-yl)-1 H-benzo[ d]imidazole by experimental techniques and quantum chemical calculations

    Özdemir, Namık; Dayan, Osman; Demirmen, Selin


    The title compound ( II), 1-(cyclohexylmethyl)-2-(pyridin-2-yl)-1 H-benzo[ d]imidazole (C19H21N3), was synthesized via N-alkylation of 2-(pyridin-2-yl)-1 H-benzo[ d]imidazole ( I). Both compounds I and II were characterized by IR, NMR and UV-vis spectroscopy. Solid-state structure of compound II was determined by single-crystal X-ray diffraction technique. Furthermore, quantum chemical calculations employing density functional theory (DFT/B3LYP) method with the 6-311++ G( d, p) basis set were performed for the theoretical characterization of the molecular and spectroscopic features of the compounds. Using the TD-DFT method, electronic absorption spectra of the compounds have been predicted at same level. When the obtained results were compared with the experimental findings, it is seen that theoretical results support the experimental data and a good agreement exists between them.

  5. Crystal structure of ethyl 2-(2,4,5-trimethoxyphenylquinoline-4-carboxylate

    T. O. Shrungesh Kumar


    Full Text Available In the title compound, C21H21NO5, the dihedral angle between the quinoline ring system (r.m.s. deviation = 0.028 Å and the trimethoxybenzene ring is 43.38 (5°. The C atoms of the methoxy groups deviate from their attached benzene ring by −0.396 (2, −0.049 (2 and 0.192 (2 Å for the ortho-, meta- and para-substituents, respectively. The pendant ethyl chain is disordered over two orientations in a 0.527 (5:0.473 (5 ratio. A short intramolecular C—H...O contact closes an S(6 ring. In the crystal, inversion dimers linked by pairs of weak C—H...O interactions generate R22(6 loops. The dimers are linked by further C—H...O interactions to generate [1-10] chains.

  6. 2-(2-Naphthyloxy)acetate derivatives. I. A new class of antiamnesic agents.

    Thamotharan, S; Parthasarathi, V; Malik, R; Jindal, D P; Piplani, P; Linden, Anthony


    The title compounds 1-(2-naphthyloxymethylcarbonyl)piperidine, C(17)H(19)NO(2), (I), and 3-methyl-1-(2-naphthyloxymethylcarbonyl)piperidine, C(18)H(21)NO(2), (II), are potential antiamnesics. In (II), the methyl-substituted piperidine ring is disordered over two conformations. The piperidine ring has a chair conformation in both compounds. In (I), the molecules are linked by weak intermolecular C-H.O interactions to give networks represented by C(4), C(6) and R(4)(4)(18) graph-set motifs, while in (II), weak intermolecular C-H.O interactions generate R(1)(2)(5), C(4) and C(7) graph-set motifs. The dihedral angle between the naphthalene moiety and the piperidine ring is 33.83 (7) degrees in (I), while it is 31.78 (11) and 19.38 (19) degrees for the major and minor conformations, respectively, in (II). PMID:12909766

  7. Bis{μ-N-[(dimethyl­amino)­dimethyl­sil­yl]-2,6-dimethyl­anilido}-κ2 N:N′;κ2 N′:N-dicopper(I)

    Chen, Juan


    The title compound, [Cu2(C12H21N2Si)2], is a binuclear CuI complex. The dimeric mol­ecule has an inversion center located at the mid-point of the Cu—Cu bond [Cu—Cu = 2.7209 (7) Å]. The bidentate ligand behaves in an N:N′-bridging mode, coordinating the metal atoms. The N—Cu—N unit is close to being linear [176.60 (8)°]. The two N atoms exhibit different affinities for the metal atom. The Cu—Namino bond is longer than the Cu—Nanilido bond by 0.079 Å. The core of the mol­ecule, the [Cu—N—Si—N]2...

  8. Structure-Triggered High Quantum Yield Luminescence and Switchable Dielectric Properties in Manganese(II) Based Hybrid Compounds.

    Wang, Zhong-Xia; Li, Peng-Fei; Liao, Wei-Qiang; Tang, Yuanyuan; Ye, Heng-Yun; Zhang, Yi


    Two new manganese(II) based organic-inorganic hybrid compounds, C11 H21 Cl3 MnN2 (1) and C11 H22 Cl4 MnN2 (2), with prominent photoluminescence and dielectric properties were synthesized by solvent modulation. Compound 1 with novel trigonal bipyramidal geometry exhibits bright red luminescence with a lifetime of 2.47 ms and high quantum yield of 35.8 %. Compound 2 with tetrahedral geometry displays intense long-lived (1.54 ms) green light emission with higher quantum yield of 92.3 %, accompanied by reversible solid-state phase transition at 170 K and a distinct switchable dielectric property. The better performance of 2 results from the structure, including a discrete organic cation moiety and inorganic metal anion framework, which gives the cations large freedom of motion. PMID:26864910

  9. 4,4-Difluoro-2,3;5,6-bis(tetramethylene-4-bora-3a,4a-diaza-s-indacene (LD540

    Kirsi Salorinne


    Full Text Available The title compound, C18H21BF2N2, is a lipophilic dye based on a BODIPY fluorophore backbone, which was developed for microscopic imaging of lipid droplets; the molecule has a planar BODIPY core [dihedral angle between the pyrrole rings = 2.3 (3°] and two tetramethylene substituents at the 2,3- and 5,6-positions in a half-chair conformation. One of the tetramethylene substituents is disordered over two two sets of sites with site occupancies of 0.5. In the crystal, pairs of C—H...F interactions link the molecules into inversion dimers. Neighbouring dimers are linked by further C—H...F interactions, forming an infinite array. C—H...π and π–π [centroid–centroid distance = 4.360 (3 Å] interactions are observed between the BODIPY core and the tetramethylene substituents of neighbouring dimer pairs.

  10. Dicty_cDB: Contig-U15427-1 [Dicty_cDB

    Full Text Available ne: mid37096, 3' end, expre... 42 6.2 1 ( BM416577 ) OP21676 Mixed Stage EST's from Globodera...836. 42 6.2 1 ( CQ597959 ) Sequence 25717 from Patent WO0171042. 42 6.2 1 ( BD187789 ) A virus in which a gene for control...lin... 38 3.3 4 ( AM449533 ) Vitis vinifera, whole genome shotgun sequence, co... 30 3.4 2 ( ER590730 ) 1093016196523 Glob...bilis cDNA c... 46 0.40 1 ( EY372542 ) CAXA14063.rev CAXA Helobdella robusta Subtracted ... 46 0.40 1 ( CP000102 ) LB5-29H21, WORKING DRAFT ... 46 0.40 1 ( EK152373 ) 1095456057773 Global-Ocean-Sampling_GS-31-01-01-1..

  11. Crystal structure of ethyl 6-chloromethyl-2-oxo-4-(2,3,4-trimethoxyphenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate

    M. Suresh


    Full Text Available In the title compound, C17H21ClN2O6, the dihydropyrimidine ring adopts a flattened envelope conformation, with the sp3-hybridized C atom forming the flap. The dihedral angle between the least-squares planes of the benzene and dihydropyrimidine rings is 88.09 (6°. An intramolecular C—H...O hydrogen bond generates an S(6 ring. In the crystal, molecules are linked via pairs of N—H...O hydrogen bonds, forming inversion dimers with an R22(8 ring motif, and the dimers are linked via further pairs of N—H...O hydrogen bonds, forming R22(14 rings and chains of molecules along [111]. Pairs of inversion-related chains are linked via weak C—H...π interactions.

  12. Crystal structures of (E)-3-(furan-2-yl)-2-phenyl-N-tosyl­acryl­amide and (E)-3-phenyl-2-(m-tol­yl)-N-tosyl­acryl­amide

    Cheng, Dong; Meng, Xiangzhen; Sheng, Zeyuan; Wang, Shuangming; Duan, Yuanyuan; Li, Ziqian


    In the title N-tosyl­acryl­amide compounds, C20H17NO4S, (I), and C23H21NO3S, (II), the conformation about the C=C bond is E. The acryl­amide groups, [–NH—C(=O)—C=C–], are almost planar, with the N—C—C=C torsion angle being −170.18 (14)° in (I) and −168.01 (17)° in (II). In (I), the furan, phenyl and 4-methyl­benzene rings are inclined to the acryl­amide mean plane by 26.47 (11), 69.01 (8) and 82.49 (9)°, respectively. In (II), the phenyl, 3-methyl­benzene and 4-methyl­benzene rings are inclin...

  13. (2E-3-(6-Chloro-2-methoxyquinolin-3-yl-1-(2-methyl-4-phenylquinolin-3-ylprop-2-en-1-one acetone monosolvate

    Edward R. T. Tiekink


    Full Text Available In the title solvate, C29H21ClN2O2·C3H6O, a prop-2-en-1-one bridge links two quinolinyl residues; the latter are almost perpendicular [dihedral angle = 78.27 (6°]. The dihedral angle between the quinonyl ring system and its pendant phenyl group is 59.78 (8°. A small twist in the bridging prop-2-en-1-one group is noted [O=C—C=C torsion angle = −10.6 (3°]. In the crystal, a three-dimensional architecture arises as a result of C—H...O and π–π stacking [centroid–centroid distances = 3.5504 (12–3.6623 (12 Å].

  14. Crystal structure of Brinzolamide: a carbonic anhydrase inhibitor.

    Zheng, Huirong; Lou, Benyong


    In crystal structure of the title compound, C12H21N3O5S3 [systematic name: (R)-4-ethyl-amino-2-(3-meth-oxy-prop-yl)-3,4-di-hydro-2H-thieno[3,2-e][1,2]thia-zine-6-sulfonamide 1,1-dioxide], there exist three kinds of hydrogen-bonding inter-actions. The sulfonamide group is involved in hydrogen bonding with the secondary amine and the meth-oxy O atom, resulting in the formation of layers parallel to the bc plane. The layers are linked by an N-H⋯O hydrogen bond involving a sulfonamide O atom as acceptor and the secondary amine H atom as donor, which gives rise to the formation of a unique bilayer structure. The absolute structure of the mol-ecule in the crystal was determined by resonant scattering [Flack parameter = 0.01 (4)]. PMID:27308020

  15. Crystal structure of Brinzolamide: a carbonic anhydrase inhibitor

    Huirong Zheng


    Full Text Available In crystal structure of the title compound, C12H21N3O5S3 [systematic name: (R-4-ethylamino-2-(3-methoxypropyl-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide], there exist three kinds of hydrogen-bonding interactions. The sulfonamide group is involved in hydrogen bonding with the secondary amine and the methoxy O atom, resulting in the formation of layers parallel to the bc plane. The layers are linked by an N—H...O hydrogen bond involving a sulfonamide O atom as acceptor and the secondary amine H atom as donor, which gives rise to the formation of a unique bilayer structure. The absolute structure of the molecule in the crystal was determined by resonant scattering [Flack parameter = 0.01 (4].

  16. Crystal structure of Brinzolamide: a carbonic anhydrase inhibitor

    Zheng, Huirong; Lou, Benyong


    In crystal structure of the title compound, C12H21N3O5S3 [systematic name: (R)-4-ethyl­amino-2-(3-meth­oxy­prop­yl)-3,4-di­hydro-2H-thieno[3,2-e][1,2]thia­zine-6-sulfonamide 1,1-dioxide], there exist three kinds of hydrogen-bonding inter­actions. The sulfonamide group is involved in hydrogen bonding with the secondary amine and the meth­oxy O atom, resulting in the formation of layers parallel to the bc plane. The layers are linked by an N—H⋯O hydrogen bond involving a sulfonamide O atom as a...

  17. Crystal structure of pencycuron

    Gihaeng Kang


    Full Text Available In the title compound [systematic name: 1-(4-chlorobenzyl-1-cyclopentyl-3-phenylurea], C19H21ClN2O, which is a urea fungicide, the cyclopentyl ring adopts an envelope conformation, with one of the methylene C atoms adjacent to the C atom bonding to the N atom as the flap. The dihedral angles between the mean planes of the central cyclopentyl ring (all atoms and the chlorobenzyl and phenyl rings are 77.96 (6 and 57.77 (7°, respectively. In the crystal, N—H...O hydrogen bonds link adjacent molecules, forming C(4 chains propagating along the b-axis direction. The chains are linked by weak π–π interactions between the chlorobenzene rings [centroid–centroid separation = 3.9942 (9 Å], resulting in two-dimensional networks extending parellel to the (110 plane.

  18. Crystal structure of pencycuron

    Kang, Gihaeng; Kim, Jineun; Kwon, Eunjin; Kim, Tae Ho


    In the title compound [systematic name: 1-(4-chloro­benz­yl)-1-cyclo­pentyl-3-phenyl­urea], C19H21ClN2O, which is a urea fungicide, the cyclo­pentyl ring adopts an envelope conformation, with one of the methyl­ene C atoms adjacent to the C atom bonding to the N atom as the flap. The dihedral angles between the mean planes of the central cyclo­pentyl ring (all atoms) and the chloro­benzyl and phenyl rings are 77.96 (6) and 57.77 (7)°, respectively. In the crystal, N—H⋯O hydrogen bonds link adj...

  19. Molten salt CO2 capture and electro-transformation (MSCC-ET) into capacitive carbon at medium temperature: effect of the electrolyte composition.

    Deng, Bowen; Chen, Zhigang; Gao, Muxing; Song, Yuqiao; Zheng, Kaiyuan; Tang, Juanjuan; Xiao, Wei; Mao, Xuhui; Wang, Dihua


    Electrochemical transformation of CO2 into functional materials or fuels (i.e., carbon, CO) in high temperature molten salts has been demonstrated as a promising way of carbon capture, utilisation and storage (CCUS) in recent years. In a view of continuous operation, the electrolysis process should match very well with the CO2 absorption kinetics. At the same time, in consideration of the energy efficiency, a molten salt electrochemical cell running at lower temperature is more beneficial to a process powered by the fluctuating renewable electricity from solar/wind farms. Ternary carbonates (Li : Na : K = 43.5 : 31.5 : 25.0) and binary chlorides (Li : K = 58.5 : 41.5), two typical kinds of eutectic melt with low melting points and a wide electrochemical potential window, could be the ideal supporting electrolyte for the molten salt CO2 capture and electro-transformation (MSCC-ET) process. In this work, the CO2 absorption behaviour in Li2O/CaO containing carbonates and chlorides were investigated on a home-made gas absorption testing system. The electrode processes as well as the morphology and properties of carbon obtained in different salts are compared to each other. It was found that the composition of molten salts significantly affects the absorption of CO2, electrode processes and performance of the product. Furthermore, the relationship between the absorption and electro-transformation kinetics are discussed based on the findings. PMID:27193751

  20. Mechanism of 2-oxoglutarate signaling by the Synechococcus elongatus PII signal transduction protein.

    Fokina, Oleksandra; Chellamuthu, Vasuki-Ranjani; Forchhammer, Karl; Zeth, Kornelius


    P(II) proteins control key processes of nitrogen metabolism in bacteria, archaea, and plants in response to the central metabolites ATP, ADP, and 2-oxoglutarate (2-OG), signaling cellular energy and carbon and nitrogen abundance. This metabolic information is integrated by P(II) and transmitted to regulatory targets (key enzymes, transporters, and transcription factors), modulating their activity. In oxygenic phototrophs, the controlling enzyme of arginine synthesis, N-acetyl-glutamate kinase (NAGK), is a major P(II) target, whose activity responds to 2-OG via P(II). Here we show structures of the Synechococcus elongatus P(II) protein in complex with ATP, Mg(2+), and 2-OG, which clarify how 2-OG affects P(II)-NAGK interaction. P(II) trimers with all three sites fully occupied were obtained as well as structures with one or two 2-OG molecules per P(II) trimer. These structures identify the site of 2-OG located in the vicinity between the subunit clefts and the base of the T loop. The 2-OG is bound to a Mg(2+) ion, which is coordinated by three phosphates of ATP, and by ionic interactions with the highly conserved residues K58 and Q39 together with B- and T-loop backbone interactions. These interactions impose a unique T-loop conformation that affects the interactions with the P(II) target. Structures of P(II) trimers with one or two bound 2-OG molecules reveal the basis for anticooperative 2-OG binding and shed light on the intersubunit signaling mechanism by which P(II) senses effectors in a wide range of concentrations. PMID:21041661

  1. Budgeting of major nutrients and the mitigation options for nutrient mining in semi-arid tropical agro-ecosystem of Tamil Nadu, India using NUTMON model.

    Surendran, U; Rama Subramoniam, S; Raja, P; Kumar, V; Murugappan, V


    Mining of nutrients from soil is a major problem in developing countries causing soil degradation and threaten long-term food production. The present study attempts to apply NUTrient MONitoring (NUTMON) model for carrying out nutrient budgeting to assess the stocks and flows of nitrogen (N), phosphorus (P), and potassium (K) in defined geographical unit based on the inputs, viz., mineral fertilizers, manures, atmospheric deposition, and sedimentation, and outputs, viz., harvested crop produces, residues, leaching, denitrification, and erosion losses. The study area covers Coimbatore and Erode Districts, which are potential agricultural areas in western agro-ecological zone of Tamil Nadu, India. The calculated nutrient balances for both the districts at district scale, using NUTMON methodology, were negative for nitrogen (N -3.3 and -10.1 kg ha(-1)) and potassium (K -58.6 and -9.8 kg ha(-1)) and positive for phosphorus (P +14.5 and 20.5 kg ha(-1)). Soil nutrient pool has to adjust the negative balance of N and K; there will be an expected mining of nutrient from the soil reserve. A strategy was attempted for deriving the fertilizer recommendation using Decision Support System for Integrated Fertilizer Recommendation (DSSIFER) to offset the mining in selected farms. The results showed that when DSSIFER recommended fertilizers are applied to crops, the nutrient balance was positive. NUTMON-Toolbox with DSSIFER would serve the purpose on enhancing soil fertility, productivity, and sustainability. The management options to mitigate nutrient mining with an integrated system approach are also discussed. PMID:27021693

  2. In situ-ATR-FTIR analysis on the uptake and release of streptomycin from polyelectrolyte complex layers

    Torger, B.; Müller, M.


    In-situ ATR-FTIR spectroscopy and line shape analysis of the diagnostic spectral region was used to quantify the bound amount and release of the antibiotic streptomycin (STRP) at polyelectrolyte (PEL) multilayers (PEM) of poly(ethyleneimine) (PEI) and poly(acrylic acid) (PAA) or PEI and sodium alginate (ALG). Unlike common concepts based on the drug enrichment of the release medium, this analytical concept allowed to measure quantitatively the drug depletion in the delivery matrix. The measured kinetic in situ ATR-FTIR data were analysed by a modified Korsmeyer-Peppas equation based on two characteristic release parameters k and n. As main experimental parameters the number of PEL layers (adsorption steps) z and the STRP/PEL ratio were varied. For z = 8 the STRP/PEL ratio showed the most significant influence on release kinetics, whereby for STRP/PEL = 1:25 slowest (n = 0.77) and lowest (k = 21.4%) and for STRP/PEL = 1:5 most rapid (n = 0.30) and highest (k = 58.6%) drug releases were found. PEM-PEI/ALG-8 (STRP/PEL = 1:5) revealed slower release rates (n = 0.58) and lower released STRP amounts (k = 17.1%) compared to PEI/PAA. UV-VIS data on time dependent STRP enrichment of the release medium showed a similar trend compared to respective ATR-FTIR data on STRP depletion in PEM. Released amounts of around 1-2 mg from the herein introduced PEM films could be determined. The introduced analytical concept will be used as screening tool for other drugs, drug eluting films and bone substituting materials.

  3. Functional studies of the gene slr2049 from Synechocystis sp. PCC6803 and its site-directed mutation.

    Liu, Bingjun; Chen, Sili; Zhang, Lei


    Phycobiliprotein is a homologous family of light-harvesting chromoproteins existing in cyanobacteria, red algae and cryptophytes. Phycobiliprotein is made up of phycobilin and its corresponding apophycobiliprotein, and they are covalently linked by the thioether bond with the bilin lyase. Using the software BLAST, we have found gene slr2049 in Synechocystis sp. PCC6803 homologous to the biliprotein lyase gene cpeS. This paper investigates the protein expressed by gene slr2049 to find the enzymatic activity characteristics. We cloned slr2049 and its related genes cpcB, ho1, and pcyA which are linked with the synthesis of phycocyanin. Special amino acid mutagenesis was performed on slr2049 to construct eight mutants slr2049 (H21S), slr2049 (L23S), slr2049 (A24S), slr2049 (F25S), slr2049 (W72L), slr2049 (G84S), slr2049 (R107S) and slr2049 (Y124S). These mutants were ligated with vectors pEDFDuet-1 and pET-23a to construct pCDF-cpcB-slr2049 wild-type, pCDF-cpcB-slr2049 mutants and pET-ho1-pcyA, for the purpose of protein expression and analysis. The results showed that the wild-type and mutants slr2049 (H21S), slr2049 (L23S), slr2049 (F25S), slr2049 (W72L), slr2049 (G84S), and slr2049 (Y124S) can catalyze CpcB to couple on PCB correctly and the products have unique spectral characteristics. However mutants slr2049 (A24S) and slr2049 (R107S) have no spectral characteristics. Thus, it is suggested that alanine at position 24 and arginine at position 107 are the active sites. PMID:25791490

  4. Ion flotation as a method of concentrating dilute solutions of uranium in sulfuric acid

    The results of experiments carried out in order to determine the possibility of extracting uranium by flotation from sulfuric acid solutions with the alkylpyridinium chlorides containing the following radicals is presented: decyl (DPC), dodecyl (doDPC), tridecyl (triDPC), tetradecyl (tetraDPC), pentadecyl (pentaDPC) and hexadecyl (hexaDPC); nicotinamide hydrobromides containing C10-C18 N-alkyl groups; hexadecylbenzyldimethylammonium bromide; bis(quaternary ammonium) salts of N,N' derivatives of hexamethylene- and ethylenediamine of the general formula ]1,2-[N,N'-bis(dimethyl)-N,N'-bis(decylacetato)]ethylenediammonium] dichloride (n = 2, R = C10H21) or ''ethonium (I)''; ]1,2-[N,N'-bis(dimethyl)-N,N'-bis(decylacetato)]hexamethylene-diammonium] dichloride (n = 6, R = C10H21) or ''ethonium (II)''; ]1,2-[N,N'-bis(dimethyl)-N,N'-bis(dodecylacetato)]hexamethylenediammonium] dichloride (n = 6, R = C12H25) or ''ethonium (III).'' Uranyl sulfate solutions of 0.005% concentration were used for the investigation. The solution pH was varied in the range 0.5-4.0. The sulfate-ion concentration was 0.1 g-ion/liter. The collectors (the surfactants listed above) were introduced into the uranium-containing test solutions in the form of 0.4% aqueous solutions, in the stoichiometric amounts required for binding UO2(SO4)34- anions. Flotation treatment of the solutions was continued for 20 min in the apparatus described in previous reports. The uranium and collector contents in the solutions were determined by standard methods. The zeta potentials of the sublate particles were determined electrophoretically

  5. Synthesis and molecular characterization of 5,5‧-((2,4-dichlorophenyl)methylene)bis(1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione)

    Barakat, Assem; Al-Najjar, Hany J.; Al-Majid, Abdullah Mohammed; Soliman, Saied M.; Mabkhot, Yahia Nasser; Ghabbour, Hazem A.; Fun, Hoong-Kun


    A simple, economical, and green approach to the synthesis of 5,5‧-((2,4-dichlorophenyl)methylene)bis(1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione) 4 using a tandem Aldol condensation-Michael addition process in aqueous diethylamine medium was described. The 3D structure of the latter was confirmed by single-crystal X-ray structure determination. The molecular structure of the titled compound was calculated using DFT B3LYP/6-311G(d,p) method. The calculated geometric parameters are in good agreement with the experimental data obtained from our reported X-ay structure. The two pyrimidinetrione rings have C16 and C20 atoms deviated significantly from the ring plane. The electronic spectra of the studied compound have been calculated using the TD-DFT method. The longest wavelength band (257.8 nm, f = 0.0276) occurs due to H → L (86%) transition. The 1H and 13C NMR calculated chemical shifts using GIAO method showed good correlation with the experimental data. The molecular electrostatic potential (MEP) showed that the most reactive sites for electrophilic and nucleophilic attacks are the carbonyl oxygen (O5) and the H21 atoms, respectively. The NBO calculations were performed to predict the natural atomic charges at the different atomic sites and to study the different intramolecular charge transfer (ICT) interactions occurring in the studied system. Interestingly, there is some delocalization of electron densities from the occupied σ-type NBO of the C20sbnd H21 to the unoccupied π∗-NBO of the two adjacent carbonyl groups.

  6. An experimental study of the mechanism of the replacement of magnetite by pyrite up to 300 °C

    Qian, Gujie; Brugger, Joël; Skinner, William M.; Chen, Guorong; Pring, Allan


    We present the results of an experimental study into the sulfidation of magnetite to form pyrite/marcasite under hydrothermal conditions (90-300 °C, vapor saturated pressures), a process associated with gold deposition in a number of ore deposits. The formation of pyrite/marcasite was studied as a function of reaction time, temperature, pH, sulfide concentration, solid-weight-to-fluid-volume ratio, and geometric surface area of magnetite in polytetrafluoroethylene-lined autoclaves (PTFE) and a titanium and stainless steel flow-through cell. Marcasite was formed only at pH 21°C 2 and formed even under basic conditions (up to pH 21°C 12-13). Marcasite formation was favored at higher temperatures. Fine-grained pyrrhotite formed in the initial stage of the reaction together with pyrite in some experiments with large surface area of magnetite (grain size PTFE liner, which is consistent with pyrite crystallizing from solution. The mechanism of the reaction is that of a dissolution-reprecipitation reaction with the precipitation of pyrite being the rate-limiting step relative to magnetite dissolution under mildly acidic conditions (e.g., pH 155°C 4.42). The experimental results are in good agreement with sulfide phase assemblage and textures reported from sulfidized Banded Iron Formations: pyrite, marcasite and pyrrhotite have been found to exist or co-exist in different sulfidized Banded Iron Formations, and the microtextures show no evidence of sub-μm-scale pseudomorphism of magnetite by pyrite.

  7. Palaeomagnetic and rock magnetic studies on the dykes of Goa, west coast of Indian Precambrian Shield

    Patil, S. K.; Rao, D. R. K.


    Detailed alternating field (AF) and thermal demagnetization techniques on 120 samples belonging to 10 dykes of the Goa region along the west coast of the Indian Precambrian Shield, have yielded characteristic remanent magnetization (ChRM) directions from 9 dykes of which 6 dykes exhibited a reverse magnetic polarity direction ( D=150°, I=44.30°, k=58, α95=5.8, N=6 dykes), while 3 dykes exhibited normal polarity D=351°, I=-50°, k=21, α95=14.9, N=3 dykes) direction. The remaining 1 dyke has shown stable direction, but with a strong overprint of the present earth field (PEF) direction, which could not be removed by either AF or thermal cleaning techniques. A Palaeomagnetic pole, computed by averaging the VGPs of 9 dykes is situated at 41.2°N 78.1°W ( N=9 dykes; A95=9.81°), which is close to that of the Deccan super pole (36.9°N, 78.8°W), suggesting that the dykes in the Goa region are related to the Deccan basaltic eruptions. Recently published 40Ar/ 39Ar dating on the normal polarity dykes of the studied area have assigned the ages as 62.8±0.2 Ma. These results demonstrate that the Deccan magnetism continued to affect western India for at least 1-2 Ma after the peak Deccan eruption during the K- T boundary. On the basis of published geological and geochemical information along with our Palaeomagnetic results, these intrusive bodies could be attributed as the feeders for the uppermost formations of Wai subgroup of the Western Ghat Deccan basalts, or to the major geodynamic events such as the opening of the Arabian Sea and the rifting of the Seychelles-Mascarene oceanic plateau, which occurred soon after the cessation of the Deccan volcanism. Rock magnetic experiments such as the Lowrie-Fuller test along with low-temperature magnetic susceptibility and isothermal remanent magnetization (IRM) measurements have identified single domain (SD) type titano-magnetite as the major characteristic remanent magnetization carrying magnetic mineral in the dyke samples.

  8. Measurement and Analysis of Specific Activities of 238U, 232Th,226Ra, 40K and 137Cs in Soil Samples from Phatthalung Province (Thailand) using Gamma Ray Spectrometry

    Full text: Specific activity of natural (238U, 232Th, 226Ra and 40K ) and anthropogenic radionuclide (137Cs) in 109 soil samples collected from 11 districts in Phathalung province have been measured and analyzed. Experimental results were obtained by using a high purity germanium (HPGe) detector and gamma spectrometry analysis system at Nuclear and Material Physics laboratory in Department of Physics Faculty of Science Thaksin University Songkhla Campus. Gamma ray radioactive standard sources 60Co, 137Cs and 133Ba were used to calibrate the measurement system. The KCl and two reference materials (RGU-1 and RGTh-1) obtained from the International Atomic Energy Agency were also used to analyze and compute the 40K, 238U (or 226Ra) and 232Th specific activity in all soil samples. The IAEA/SL-2 was also used to evaluate the specific activity of 137Cs in all soil samples. The measuring time of each sample was 10,800 seconds. It was found that specific activity ranged from 148.17 to 11276.78 Bq/kg for 40K, 58.29 to 518.45 Bq/kg for 226Ra, 8.40 to 236.19 Bq/kg for 232Th and 0.00 tp 12.39 Bq/kg for 137Cs with mean values of 3573.35 ± 203.89 Bq/kg, 135.89 ± 6.71 Bq/kg, 76.34 ± 5.32 Bq/kg and 1.05 ± 0.70 Bq/kg respectively. Furthermore, absorbed dose rate in air (D), radium equivalent activity (Raeq), external hazard index (Hex), and annual effective dose rate (AEDout) of this area were also evaluated by using the mean values of specific activities of the 40K, 226Ra and 232Th. Moreover, the experimental results were also compared with Office of Atoms for Peace (OAP) research data, Thailand and global radioactivity measurement and evaluations. The radioactive contour maps of specific activities of natural and anthropogenic radionuclides from this study were created by using the program ArcGis Version 9.2

  9. Wave motions in the lower thermosphere during the energy budget campaign 1980 from three locations in the northern hemisphere

    Cevolani, G.; Dardi, A.; Formiggini, C. (Consiglio Nazionale delle Ricerche, Bologna (Italy)); Kingsley, S.P.; Muller, H.G. (Sheffield Univ. (UK). Dept. of Physics)

    Simultaneous meteor radar wind observations were made at Budrio (Italy,45 deg N), Sheffield (U.K.,53 deg N) and Stornoway (U.K.,58 deg N) during the Energy Budget Campaign (EBC), November-December 1980, in the altitude region between 75 and 115 km. Wind results are presented in terms of prevailing components an oscillations of different time scales: tidal (8,12 and 24 h), gravity ((3/6)h) and planetary ((2/10) days) waves. The seasonal variation of the prevailing zonal components observed at the three stations in previous years shows the same maxima of Summer and Winter, as well as the equinactial minima exhibited by the CIRA 19972 model for 50 deg N. The data show marked tidal activity with the semi-diurnal tide which exceeds in amplitude any other mode in the wind spectra. Tidal amplitudes recorded at Budrio appear more significantly lower than those recorded at Sheffield and Stornoway. Variations of the amplitude of maxima of the semi-diurnal oscillation relative to the Budrio and Sheffield data show time scales generally greater than 5 days throughout the recording period. The diurnal and terdiurnal tides represent a small part of the total wind energy in the meteor zone and exhibit phases which disagree strongly at the quoted stations. The scatter in the hourly data is representative of small-scale wind disturbances due to internal gravity waves: at Budrio, by using the MEM method for individual day's data (November 23-24, 28-29, 1980), gravity waves with vertical wave-lengths of (20/45) km, periods of 3.5, 4.5 and 6 h, and amplitudes of the order of 10 ms/sup -1/ have been observed. Long-period oscillations with periods in the (2/10) day time interval have been identified in the wind patterns at Budrio and Sheffield, but the presence of planetary waves of quasi-2-day period was less significant than during a previous Summer 1980 run carried out at the same stations.

  10. Construction of an ''intelligent'' trigger system for kaons and study of the K+ production in the system Ne+NaF at 1.0 GeV/u

    The technical part of this thesis describes the construction, the properties, and the experience from the application of an intelligent software trigger for the experiments on the production of positive kaons at the kaon spectrometer. The software trigger was applied in several beam-times. An essiential improvement in the yield of the registrated kaons was reached. The realization ensued by the application of standard components and represents a flexible and cost-efficient solution. The physical part of this thesis deals with the measurement of the double-differential cross section for positive kaons, positive pions, and protons in the system Ne+NaF at 1.0 GeV/u beam energy in the laboratory-angle range ofΘlab=44 ±4 . the beam energy of 1.0 GeV/u lies below the threshold energy for the production of positive kaons in the collision of two free nucleons of Ebeamthreshold=1.58 GeV. The momentum spectra of kaons and pions in the laboratory-momentum range from 270 MeV/c to 1140 MeV/c can be well described by a Boltzmann distribution in the c. m. system. The steepness parameter of the Boltzmann distributions amount to 64 MeV for kaons and 58 MeV for pions. The momentum-integrates cross section were determined from the extrapolation of the fitted Boltzmann distributions to: (dσ/dΩlab)ΔΩlabK+=58.6±9.2 μb/sr and (dσ/dΩlab)ΔΩlabπ+=169±17 mb/sr. The total cross sections were calculated under the assumption of the isotropy in the c. m. system from the fitted distributions: σ0K+=335±52 μb and σ0π+=939±96 mb. The mass dependence of the meson production cross sections in the symmetrc collisional system Ne+NaF was studied and compared with the results of the study of the heavy collisional system Au+Au

  11. AlGaN/GaN-based HEMT on SiC substrate for microwave characteristics using different passivation layers

    T R Lenka; A K Panda


    In this paper, a new gate-recessed AlGaN/GaN-based high electron mobility transistor (HEMT) on SiC substrate is proposed and its DC as well as microwave characteristics are discussed for Si3N4 and SiO2 passivation layers using technology computer aided design (TCAD). THe two-dimensional electron gas (2DEG) transport properties are discussed by solving Schödinger and Poison equations self-consistently resulting in various subbands having electron eigenvalues. From DC characteristics, the saturation drain currents are measured to be 600 mA/mm and 550 mA/mm for Si3N4 and SiO2 passivation layers respectively. Apart from DC, small-signal AC analysis has been done using two-port network for various microwwave parameters. The extrinsic transconductance parameters are measured to be 131.7 mS/mm at a gate voltage of $V_{gs} = -0.35$ V and 114.6 mS/mm at a gate voltage of $V_{gs} = -0.4$ V for Si3N4 and SiO2 passivation layers respectively. The current gain cut-off frequencies $(f_{t})$ are measured t be 27.1 GHz and 23.97 GHz in unit-gain-point method at a gate voltage of -0.4 V for Si3N4 and SiO2 passivation layers respectively. Similarly, the power gain cut-off frequencied $(f_{max})$ are measured to be 41 GHz and 38.5 GHz in unit-gain-point method at a gate voltage of -0.1 V for Si3N4 and SiO2 passivation layers respectively. Furthermore, the maximum frequency of oscillation or unit power gain (MUG = 1) cut-off frequencies for Si3N4 and SiO2 passivation layers are measured to be 32 GHz and 28 GHz respectively from MUG curves and the unit current gain, $|h_{21}| = 1$ cut-off frequencies are measured to be 140 GHz and 75 GHz for Si3N4 and SiO2 passivation layers respectively from the $abs |h_{21}|$ curves. HEMT with Si3N4 passivation layer giver better results than HEMT with SiO2 passivation layer.

  12. Preparation of Monoclonal Antibody and Development of Enzyme-linked Immunosorbent Assay Specific for Escherichia coli O157 in Foods


    Objective To prepare monoclonal antibodies (Mab) and antisera specific for Escherichia coli (E.coli) O157, and to develop a sandwich enzyme-linked immunosorbent assay (ELISA) to detect E.coli O157 in foods. Methods Spleen cells from BALB/c mice immunized with the somatic antigen of E.coli O157:H7 were fused with murine Sp2/0 myeloma cells. The hybridoma cell line specific for E.coli O157 was established after having been subcloned. Antisera specific for E.coli O157 was prepared by intravenous injection into New Zealand rabbits with a stain of E.coli O157:H7. The sandwich ELISA was developed with the polyclonal antibody as the capture antibody and the Mab 3A5 as the detection antibody. The inoculated ground poultry meat and pasteurized milk were tested to confirm efficiency of the method. Results Mab 3A5 specific for E.coli O157 and O113:H21 belonged to subtype IgM. The ascetic titers of the antibody was 1:1×106. No cross-reactivity of the Mab was observed with strains of Salmonella spp, Yersinia enterocolitica, Shigella dysenteriae, etc. The purified polyclonal antibody had a titer of 1:1×105 with E.coli O157. The detection limit of this sandwich ELISA was 103-104 cfu E.coli O157/mL in pure culture with a high specificity, which was characterized by every non-O157 strain with negative response. With 10h enrichment procedure, E.coli O157:H7 recovered well from inoculated ground poultry meat and pasteurized milk at levels of 0.1 cfu/g and 0.1 cfu/mL. Conclusion Mab 3A5 specific for E.coli O157 and O113:H21 can be produced by immunizing BALB/c mice with a strain of E.coli O157:H7. Then a sandwich ELISA can be developed with the polyclonal antibody as the capture antibody and the Mab 3A5 as the detection antibody. The method is proved to be a sensitive and specific technique to detect low number of E.coli O157 in food.

  13. Chemical composition of PM2.5 from two tunnels with different vehicular fleet characteristics.

    Cui, Min; Chen, Yingjun; Tian, Chongguo; Zhang, Fan; Yan, Caiqing; Zheng, Mei


    The chemical compositions of PM2.5 including OC, EC, water soluble ions, elements, and organic components such as polycyclic aromatic hydrocarbons (PAHs), hopanes, and steranes, emitted in Wuzushan (WZS) and Kuixinglou (KXL) tunnels were determined. WZS tunnel is a major route for diesel vehicles traveling, while KXL tunnel has limited to diesel vehicles. The results showed that the proportions of the different constituents of PM2.5 in the Wuzushan (WZS) tunnel were OC (27.7%), EC (32.1%), elements (13.9%), and water soluble ions (9.2%). Whereas the chemical profile of PM2.5 in the Kuixinglou (KXL) tunnel was OC (17.7%), EC (10.4%), elements (8.90%), and water soluble ions (8.87%). The emission factors (EFs) of PM2.5 and proportions of SO4(2-) and Pb were decreased by vehicle emission standards and fuel quality policy in China, and the higher molecular weight PAHs (4+5+6 rings) were more abundant than the lower molecular weight PAHs (2+3 rings) in the two tunnels. The proportions of 17A(H)-21B(H)-30-Norhopane and 17A(H)-21B(H)-Hopane in the hopane and sterane were not dependent on the vehicles types. In addition, specific composition profiles for PM2.5 from gasoline-fueled vehicles (GV) and diesel-fueled vehicles (DV) emissions were drafted, which indicated that OC (0.974mg·veh(-1)·km(-1)) was the most abundant component in PM2.5, followed by Fe, Cl(-), and Mg for GV. The relative proportions of the different constituents in the PM2.5 for DV were EC (35.9%), OC (27.2%), elements (12.8%), and water soluble ions (11.7%). Both the PM2.5 EFs and EC proportions in DV were higher than those in GV, and the HMW PAHs were the dominant PAHs for both GV and DV. The PM2.5 emissions from the vehicles in Yantai were 581±513tons to 1353±1197tons for GV, and 19,627±2477tons to 23,042±2887tons for DV, respectively. PMID:26808403

  14. Crystal structure of 3-(3,4,5-trimethoxyphenyl-1,2,3,4-tetrahydrocyclopenta[b]indole-2-carboxylic acid

    Daniara Fernandes


    Full Text Available In the title compound, C21H21NO5, obtained from a Morita–Baylis–Hillman adduct, the hydrogenated five-membered ring adopts a shallow envelope conformation, with the C atom bearing the carboxylic acid substituent deviating by 0.237 (1 Å from the mean plane of the other four atoms (r.m.s. deviation = 0.007 Å. The dihedral angle between the fused ring system (all atoms; r.m.s. deviation = 0.057 Å and the pendant trimethoxy benzene ring is 66.65 (3°. The C atoms of the meta-methoxy groups lie close to the plane of the benzene ring [deviations = 0.052 (1 and −0.083 (1 Å], whereas the C atom of the para-methoxy group is significantly displaced [deviation = −1.289 (1 Å]. In the crystal, carboxylic acid inversion dimers generate R22(8 loops. The dimers are connected by N—H...O hydrogen bonds, forming [011] chains. A C—H...O interaction is also observed.

  15. Synthesis and Crystal Structure of N-(1'-H-Pyrrol-2'-ylcarbonyl)-5-amino-1,10-phenanthroline

    WANG Yue-Hong; LIN Hai; LIN Hua-Kuan


    The title compound,N-(1'-H-pyrrol-2'-ylcarbonyl)-5-amino-1,10-phenanthroline,was synthesized by the reaction of a-pyrrolyl carbonyl chloride and 5-amino-1,10-phenanthroline in pyridine.Determined by X-ray structure analysis,it crystallizes in triclinic system,space group P(1)with the following crystallographic data:C20H21N5O3,Mr=379.42,a=7.8559(4),b=9.1681(6),c =14.6818(9)(A),α=73.254(10),β=88.938(15),γ=68.080(10)°,V=934.66(10)(A)3,Z=2,F(000)=400.Dc=1.348 g/cm3 and μ=0.094 mm-1.The final R=0.0680 and wR=0.1419 for 2142observed reflections with I>2σ(I),and R=0.1084 and wR=0.1643 for all reflections.Two aromatic ring planes(pyrrole and phenanthroline rings)are connected by the amide plane.Two title complex molecules are connected through hydrogen bonds and weak π-π stacking interactions to generate a 3-D supramolecule.

  16. X-Ray Transient in Musca (GRS 1121-68 = GS 1124-683)

    Lund, Niels; Brandt, Søren; Makino, F.;


    Crab and increasing slowly during the observation. The source remained at a constant intensity level on Jan. 10. On Jan. 5 this source was not bright enough to be detectable by WATCH. The preliminary position is R.A. = 11h21m, Decl. = -68.1 deg (equinox 1950.0; uncertainty about 1 deg). We have not...... found any catalogued hard x-ray sources within our error circle; however, close to the given position, we have noted the existence of a radio pulsar (at R.A. = 11h10m, Decl. = -69 deg) with a period of 0.8 s, and a gamma-ray burst source, GRB 820829B, detected by Venera 13/14 in 1982. We have not...... detected any strong pulsations from the new source, but the time resolution of the available data does not allow a search for pulsations with periods shorter than about 20 s." F. Makino and the Ginga Team, Institute of Space and Astronautical Science, telex: "A bright transient x-ray source, designated GS...

  17. Bis(3,5-dimethyl-1H-pyrazole-κN2bis(3,3′′,5,5′′-tetramethyl-[1,1′:3′,1′′-terphenyl]-2′-carboxylato-κOiron(II dichloromethane monosolvate

    Yeojin Jeon


    Full Text Available In the title compound, [Fe(C23H21O22(C5H8N22]·CH2Cl2, the Fe2+ cation is coordinated by the N atoms of two 3,5-dimethylpyrazole ligands and the carboxylate O atoms from two tetramethylterphenylcarboxylate ligands, forming an FeN2O2 polyhedron with a slightly distorted tetrahedral coordination geometry. Intramolecular N—H...O and C—H...O hydrogen-bonding interactions stabilize the molecular conformation. The dihedral angles formed by the central benzene ring with the outer benzene rings of the terphenyl groups are 47.92 (8, 59.38 (8, 48.24 (8 and 52.37 (8°. The dichloromethane solvent molecule interacts with the complex molecule via a C—H...O hydrogen bond. In the crystal, centrosymmetrically related complex molecules are linked into dimers through pairs of C—H...O hydrogen bonds.

  18. Effect of two human growth hormone receptor antagonists on glomerulosclerosis in streptozotocin-induced diabetic rats

    Wei LI; Shui-xian SHEN; Li-hua ZHU; En-bi WANG; Zeng-can YE; Jun LIN; Li-he GUO; Fei-hong LUO; Xi-hong LIU; Xin FANG


    AIM: To explore the feasibility of human growth hormone (hGH) receptor antagonist in the treatment of end-stage diabetic renal complications. METHODS: Two hGH mutants, hGHA1 (Cys-hGH-dell-4, G120R, K168A, E174A,C182S, de1186-191) and hGHA2 (hGH-H21A, G120R, E174A) were expressed in E coli. The IC50 (Mean±SD)values for the mutants for inhibiting 125I-hGH binding to rabbit growth hormone receptor were (65±10) ng for hGHA1, (27±5.6) ng for hGHA2, and (10±0.6) ng for wild type hGH, respectively. RESULTS: After treatment for 12 weeks, the renal histology analysis showed that treatment with hGHA2 at 4 mg/kg body weight daily markedly suppressed glomerulosclerosis in streptozotocin-induced diabetic Sprague-Dawley (SD) rats; hGHA1 at the same dosage slightly increased the renal damage compared with saline; while wild type hGH at 1 U/kg body weight daily severely worsened the glomerulo-sclerosis in diabetic SD rats. CONCLUSION: The data indicated that hGHA2 inhibited the end-stage glomerulosclerosis in diabetic rats, but hGHA1 mildly increased the glomerulosclerosis.

  19. Asteroid 2012 XE133, a transient companion to Venus

    Marcos, C de la Fuente


    Apart from Mercury that has no known co-orbital companions, Venus remains as the inner planet that hosts the smallest number of known co-orbitals, 2: (322756) 2001 CK32 and 2002 VE68. Both objects have absolute magnitudes 18 < H < 21 and were identified as Venus co-orbitals in 2004. Here, we analyze the orbit of the recently discovered asteroid 2012 XE133 with H = 23.5 mag to conclude that it is a new Venus co-orbital currently following a transitional trajectory between Venus' Lagrangian points L5 and L3. The object could have been a 1:1 librator for several thousand years and it may leave the resonance with Venus within the next few hundred years, after a close encounter with the Earth. Our calculations show that its dynamical status as co-orbital, as well as that of the 2 previously known Venus co-orbitals, is controlled by the Earth-Moon system with Mercury playing a secondary role. The 3 temporary co-orbitals follow rather chaotic but similar trajectories with e-folding times of order of 100 yr. Ou...

  20. Characterisation of hydrogen embrittlement cracking at Ta/Zr bond interface and hydrogen embrittlement mechanism of Zr base metal. Hydrogen embrittlement in SUS304ULC/Ta/Zr explosive bonded joint

    In order to clarify the behaviour and mechanism of the hydrogen embrittlement in SUS304ULC/Ta/Zr explosive bonded joint, the hydrogen embrittlement cracking at Ta/Zr bond interface was characterised. Cracks occurred in the Zr substrate along the wavy interface of the hydrogen-charged Ta/Zr joint. The cracking susceptibility increased drastically when the potential of specimen during hydrogen-charging was reduced below the redox potential of hydrogen, γ-ZrH and δ-ZrH were precipitated in the hydrogen-charged Zr and the precipitated γ-ZrH possessed a (0002)α-Zr parallel (11-bar1)γ-ZrH, [21-bar1-bar0]α-Zr parallel [110]γ-ZrH crystallographic relationship. An in-situ observation of the hydrogen embrittlement cracking with SEM and TEM revealed that cracks were initiated in zirconium hydrides and propagated preferentially along zirconium hydrides. These results suggested that the hydrogen embrittlement mechanism of the Zr base metal was caused by the precipitation of zirconium hydrides and the brittle fracture of them. (author)

  1. Physiological and behavioural responses of Gammarus pulex (Crustacea: Amphipoda) exposed to cadmium

    The aim of this study was to investigate the effects of cadmium on physiological and behavioural responses in Gammarus pulex. In a first experiment, cadmium LC50s for different times were evaluated in 264 h experiment under continuous mode of exposure (LC5096h = 82.1 μg L-1, LC50120h = 37.1 μg L-1, LC50168h = 21.6 μg L-1, LC50264h = 10.5 μg L-1). In a second experiment, the physiological and behavioural responses of the amphipod exposed to cadmium (0, 7.5 and 15 μg L-1) were investigated under laboratory conditions. The mortality and the whole body cadmium concentration of organisms exposed to cadmium were significantly higher than in controls. Concerning physiological responses, cadmium exposure exerted a significant decrease on osmolality and haemolymph Ca2+ concentration, but not on haemolymph Na+ and Cl- concentrations, whereas the Na+/K+-ATPase activity was significantly increased. Behavioural responses, such as feeding rate, locomotor and ventilatory activities, were significantly reduced in Cd exposed organisms. Mechanism of cadmium action and consequent energetic reallocation in favour of maintenance functions (i.e., osmoregulation) are discussed. The results of this study indicate that osmolality and locomotor activity in G. pulex could be effective ecophysiological/behavioural markers to monitor freshwater ecosystem and to assess the health of organisms

  2. The Multiwavelength Survey by Yale-Chile (MUSYC): Deep Near-Infrared Imaging and the Selection of Distant Galaxies

    Quadri, R; van Dokkum, P; Gawiser, E; Franx, M; Lira, P; Rudnick, G; Urry, C M; Maza, J; Kriek, M; Barrientos, L F; Blanc, G; Castander, F J; Christlein, D; Coppi, P S; Hall, P B; Herrera, D; Infante, L; Taylor, E N; Treister, E; Willis, J P; Quadri, Ryan; Marchesini, Danilo; Dokkum, Pieter van; Gawiser, Eric; Franx, Marijn; Lira, Paulina; Rudnick, Gregory; Maza, Jose; Kriek, Mariska; Blanc, Guillermo; Castander, Francisco J.; Christlein, Daniel; Coppi, Paolo S.; Hall, Patrick B.; Herrera, David; Infante, Leopoldo; Taylor, Edward N.; Treister, Ezequiel; Willis, Jon P.


    We present deep near-infrared JHK imaging of four 10'x10' fields. The observations were carried out as part of the Multiwavelength Survey by Yale-Chile (MUSYC) with ISPI on the CTIO 4m telescope. The typical point source limiting depths are J~22.5, H~21.5, and K~21 (5sigma; Vega). The effective seeing in the final images is ~1.0". We combine these data with MUSYC UBVRIz imaging to create K-selected catalogs that are unique for their uniform size, depth, filter coverage, and image quality. We investigate the rest-frame optical colors and photometric redshifts of galaxies that are selected using common color selection techniques, including distant red galaxies (DRGs), star-forming and passive BzKs, and the rest-frame UV-selected BM, BX, and Lyman break galaxies (LBGs). These techniques are effective at isolating large samples of high redshift galaxies, but none provide complete or uniform samples across the targeted redshift ranges. The DRG and BM/BX/LBG criteria identify populations of red and blue galaxies, r...

  3. Molecular structure, spectroscopic and quantum chemical studies of 1‧,3‧,3‧-trimethylspiro[benzo[f]chromene-3,2‧-indoline

    Asiri, Abdullah M.; Ersanlı, Cem Cüneyt; Şahin, Onur; Arshad, Muhammad Nadeem; Hameed, Salem A.


    In this work, synthesis, X-ray single crystal determination, nuclear magnetic resonance (1H NMR and 13C NMR), Ultraviolet-Visible (UV-vis), Fourier transform infrared spectroscopy (FT-IR) and quantum mechanical studies of the 1‧,3‧,3‧-trimethylspiro[benzo[f]chromene-3,2‧-indoline [(C23H21NO), TMSBCI] have been both experimentally and theoretically reported. The molecular structure obtained from X-ray single-crystal analysis of the investigated compound in the ground state has been compared using Hartree-Fock (HF) and density functional theory (DFT) with the functional B3LYP using the 6-31G(d,p) as basis set. In addition to the optimized geometrical structures, atomic charges, molecular electrostatic potential (MEP) and natural bond orbital (NBO) have been investigated by using B3LYP/6-31G(d,p) level of the theoretical approximation for the title compound. The energetic behavior of TMSBCI has been examined in solvent media using polarizable continuum model (PCM). The total dipole moment (μ), the average linear polarizability (α), and the first-order hyperpolarisability (β) values of the investigated molecule have been computed using the same method. The experimental measurements (1H NMR, 13C NMR and UV-vis) have been compared with its corresponding the calculated values (using DFT). Besides, frontier molecular orbitals (FMOs) and thermodynamic properties have also been studied.

  4. catena-Poly[2,2′,2′′-nitrilotris(ethanaminium [tri-μ-oxido-tris[dioxidovanadate(V

    Kelvin B. Chang


    Full Text Available The title compound, {(C6H21N4[V3O9]·H2O}n, crystallizes as a salt with [trenH3]3+ cations [tren is tris(2-aminoethylamine], and one-dimensional anionic {[VVO3]−}n (metavanadate chains along the c-axis direction. Three crystallographically distinct VV sites and one occluded water molecule are present for every [trenH3]3+ cation in the unit cell. The {[VVO3]−}n chains are composed of vertex-sharing [VO4] tetrahedra and have a repeat unit of six tetrahedra. Each tetrahedron in the chain contains two terminal and two μ2-bridging oxide ligands. The [trenH3]3+ cations, {[VVO3]−}n anions and occluded water molecules participate in an extensive three-dimensonal hydrogen-bonding network. The three terminal ammonium sites of the [trenH3]3+ cations each form strong N—H...O hydrogen bonds to terminal oxide ligands on the {[VVO3]−}n chain. Each occluded water molecule also donates two O—H...O hydrogen bonds to the terminal oxide ligands.

  5. Mirror Symmetry of Minimal Calabi-Yau Manifolds

    Kawada, Hideyuki; Suzuki, Hisao


    We perform the mirror transformations of Calabi-Yau manifolds with one moduli whose Hodge numbers $(h^{11}, h^{21})$ are minimally small. Since the difference of Hodge numbers is the generation of matter fields in superstring theories made of compactifications, minimal Hodge numbers of the model of phenomenological interest are (1,4). Genuine minimal Calabi-Yau manifold which has least degrees of freedom for K\\"ahler and complex deformation is (1,1) model. With help of {\\it Mathematica} and {\\it Maple}, we derive Picard-Fuchs equations for periods, and determine their monodromy behaviors completely such that all monodromy matrices are consistent in the mirror prescription of the model (1,4), (1,3) and (1,1). We also discuss to find the description for each mirror of (1,3) and (1,1) by combining invariant polynomials of variety on which (1,5) model is defined. The genus 0 instanton numbers coming from mirror transformations in above models look reasonable. We propose the weighted discriminant for genus 1 insta...

  6. Photoinduced Charge Separation in Porphyrin Ion Pairs.

    Natali, Mirco; Scandola, Franco


    Ion pairs between porphyrin-type compounds have been successfully employed for spectral sensitization of semiconductor surfaces and for the preparation of collective binary ionic materials for photonic and (photo)catalytic applications. The understanding of the photophysical processes occurring within ion-paired porphyrin dimers is thus of remarkable importance for the optimization and improvement of such systems. Herein the ion-pair species formed between ZnTMePyP(4+) (Zn1) or H2TMePyP(4+) (H21) and ZnTPPS(4-) (Zn2) or H2TPPS(4-) (H22) in a variety of solvent mixtures are characterized and their photophysics thoroughly investigated by time-resolved techniques. In all the systems studied, very fast and efficient photoinduced charge separation is observed, with the cationic porphyrin being reduced and the anionic one oxidized. Interestingly, despite the very short charge separation distance, the lifetime for charge recombination, depending on the energy gap, can extend into the nanosecond time domain, showing great potential for the utilization of this molecular design within energy conversion schemes. PMID:26905260

  7. Vanadia-silica and vanadia-cesium-silica catalysts for oxidation of SO2

    Pârvulescu, Vasile I.; Paun, Christina; Pârvulescu, Viorica;


    Mesoporous vanadia-silica catalysts have been prepared by three different sol-gel procedures using tetraethylorthosilicate (TEOS), vanadyl acetylacetonate (VAA), or VOCl3 and in some cases quaternary ammonium salts ((CH3)(3)C14H29N+Br- or (C10H21)(4)N+Br-) as surfactants. According to procedure A......, TEOS and VAA were concomitantly hydrolyzed, in procedure B TEOS was prehydrolized and vanadium precursor was added to the silica sol, and in procedure C both TEOS and vanadium precursors were separately prehydrolized. The sol-gel procedures were controlled by checking the effect of the hydrolysis p...... calcination of the V/Cs catalysts vanadia is dissolved in a sulfate containing molten salt. The activity of these catalysts for the oxidation of SO2 was tested in a gas containing 2% SO2, 19% O-2, 79% N-2 in the temperature range 523-823 K. Similar experiments with gases containing 10% H2O in the feed or with...

  8. Crystal structure of (4-meth-oxy-phen-yl)[(4-meth-oxy-phen-yl)phospho-nato]dioxidophosphate(1-) 2-amino-6-benzyl-3-eth-oxy-carbon-yl-4,5,6,7-tetra-hydro-thieno[2,3-c]pyridin-6-ium.

    Mague, Joel T; Mohamed, Shaaban K; Akkurt, Mehmet; Younes, Sabry H H; Ahmed, Essam K; Albayati, Mustafa R


    The asymmetric unit of the title mol-ecular salt, C17H21N2O2S(+)·C14H15O7P2 (-), comprises two cations and two anions. Each cation features an intra-molecular N-H⋯O hydrogen bond, which closes an S(6) ring; in each case the hydro-pyridine ring adopts a half-chair conformation. In the anions, the dihedral angles between the aromatic rings are 64.1 (2) and 54.9 (2)°. In each case, the diphosphate groups are close to eclipsed [C-P⋯P-C pseudo-torsion angles = 11.6 (2) and -19.3 (2)°]. One of the meth-oxy groups in each anion is disordered over two orientations in a 0.539 (18):0.461 (18) ratio in one anion and 0.82 (2):0.18 (2) in the other. In the crystal, O-H⋯O and N-H⋯O hydrogen bonds link the components into [100] chains. Numerous C-H⋯O inter-actions cross-link the chains into a three-dimensional network. PMID:26870570

  9. 1-(3,5-Diethyl-1H-pyrazol-1-yl-3-phenylisoquinoline

    F. Nawaz Khan


    Full Text Available In the title molecule, C22H21N3, the isoquinoline ring is almost planar [maximum deviation = 0.046 (1 Å] and makes dihedral angles of 52.01 (4 and 14.61 (4° with the pyrazole and phenyl rings, respectively. The phenyl ring and the pyrazole ring are twisted by 44.20 (6° with respect to each other. The terminal C atoms of both of the ethyl groups attached to the pyrazole ring are disordered over two sites with occupancy ratios of 0.164 (7:0.836 (7 and 0.447 (16:0.553 (16. A weak intramolecular C—H...N contact may influence the molecular conformation. The crystal structure is stabilized by C—H...π contacts involving the phenyl and pyrazole rings, and by π–π stacking interactions involving the pyridine and benzene rings [centroid–centroid distance = 3.5972 (10 Å].

  10. The Identification of the X-ray Counterpart to PSR J2021+4026

    Weisskopf, Martin C; Razzano, Massimiliano; Belfiore, Andrea; Parkinson, Pablo Saz; Ray, Paul S; Kerr, Matthew; Harding, Alice; Swartz, Douglas A; Carraminana, Alberto; Ziegler, Marcus; Becker, Werner; De Luca, Andrea; Dormody, Michael; Thompson, David J; Kanbach, Gottfried; Elsner, Ronald F; O'Dell, Stephen L; Tennant, Allyn F


    We report the probable identification of the X-ray counterpart to the gamma-ray pulsar PSR J2021+4026 using imaging with the Chandra X-ray Observatory ACIS and timing analysis with the Fermi satellite. Given the statistical and systematic errors, the positions determined by both satellites are coincident. The X-ray source position is R.A. 20h21m30.733s, Decl. +40 deg 26 min 46.04sec (J2000) with an estimated uncertainty of 1.3 arsec combined statistical and systematic error. Moreover, both the X-ray to gamma-ray and the X-ray to optical flux ratios are sensible assuming a neutron star origin for the X-ray flux. The X-ray source has no cataloged infrared-to-visible counterpart and, through new observations, we set upper limits to its optical emission of i' >23.0 mag and r' > 25.2mag. The source exhibits an X-ray spectrum with most likely both a powerlaw and a thermal component. We also report on the X-ray and visible light properties of the 43 other sources detected in our Chandra observation.

  11. Deep VLT infrared observations of X-ray Dim Isolated Neutron Stars

    Curto, G Lo; Perna, R; Israel, G L


    X-ray observations have unveiled the existence of a family of radio-quiet Isolated Neutron Stars whose X-ray emission is purely thermal, hence dubbed X-ray Dim Isolated Neutron Stars (XDINSs). While optical observations have allowed to relate the thermal emission to the neutron star cooling and to build the neutron star surface thermal map, IR observations are critical to pinpoint a spectral turnover produced by a so far unseen magnetospheric component, or by the presence of a fallback disk. The detection of such a turnover can provide further evidence of a link between this class of isolated neutron stars and the magnetars, which show a distinctive spectral flattening in the IR. Here we present the deepest IR observations ever of five XDINSs, which we use to constrain a spectral turnover in the IR and the presence of a fallback disk. The data are obtained using the ISAAC instrument at the VLT. For none of our targets it was possible to identify the IR counterpart down to limiting magnitudes H = 21.5 - 22.9. ...

  12. Crystal structures of two (±-exo-N-isobornylacetamides

    Dmitrijs Stepanovs


    Full Text Available The title compounds consist of a bornane skeleton with attached acetamide, C12H21NO (±-(1 {systematic name: (±-N-[(1RS,2RS,4RS-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl]acetamide}, and chloroacetamide, C12H20ClNO (±-(2 {systematic name: (±-2-chloro-N-[(1RS,2RS,4RS-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl]acetamide}, functionalities to the 2-exo-position. The crystal structure of the first monoclinic polymorph of (±-(1 has been reported previously [Ung et al. (2014. Monatsh. Chem. 145, 983–992]. Compound (±-(1 crystallizes in the space group P21/n with two independent molecules in the asymmetric unit, in contrast to the above-mentioned polymorph which crystallized in the space group C2/c with one molecule in the asymmetric unit. In the title compounds, the bicyclic bornane moieties have normal geometries. In the crystals of both compounds, molecules are linked by N—H...O hydrogen bonds, reinforced by C—H...O contacts, forming trans-amide chains propagating along the a-axis direction. In the case of compound (±-(1, neighbouring chains are linked by further C—H...O contacts, forming double-chain ribbons along [100].

  13. Determination of arterial wall shear stress

    LIU; Zhaorong


    [1]Langille, B. L., 7Donnell, F., Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent, Science, 1986, 231: 405—407.[2]Langer, R., Vacanti, J. P., Tissue engineering, Science, 1993, 260: 920—926.[3]Kamiya, A., Togawa, T., Adaptive regulation of wall shear stress to flow change in the canine carotid artery, Am. J. Physiol. (Heart Circ. Physiol.), 1980, 239: H14—H21.[4]Fung, Y. C., Biomechanics: Motion, Flow, Stress, and Growth, New York: Springer-Verlag, 1990.[5]Liu, S. Q., Biomechanical basis of vascular tissue engineering, Critical Reviews in Biomedical Engineering, 1999, 27: 75—148.[6]Ando, J., Kamiya, A., Blood flow and vascular endothelium cell function, Frontiers Med. Biological Eng., 1993, 5: 245—264.[7]Ku, D. N., Giddens, D. P., Zarins, D. K. et al., Pulsatile flow and atherosclerosis in the human carotid bifurcation-positive correlation between plaque location and low and oscillating shear stress, Atherosclerosis, 1985, 5: 293—302.[8]Liu Zhaorong, Li Xixi, Theory and Method on Hemodynamics (in Chinese), Shanghai: Fudan University Press, 1997.

  14. Investigation of structural, morphological and electrical properties of APCVD vanadium oxide thin films

    Vanadium oxide films were chemically vapor deposited (CVD) on oxidized Si substrates covered with CVD tungsten (W) thin films and on glass substrates covered with indium tin oxide (ITO) films, using vanadium(V) oxy-tri-isopropoxide (C9H21O4V) vapors. X-ray diffraction (XRD) measurements showed that the deposited films were composed of a mixture of vanadium oxides; the composition was determined mainly by the deposition temperature and less by the precursor temperature. At temperatures up to 450 C the films were mostly composed by monoclinic VO2. Other peaks corresponding to various vanadium oxides were also observed. X-ray microanalysis confirmed the composition of the films. The surface morphology was studied with atomic force microscopy (AFM) and scanning electron microscopy (SEM). These measurements revealed that the morphology strongly depends on the used substrate and the deposition conditions. The well-known metal-insulator transition was observed near 75 C for films mostly composed by monoclinic VO2. Films deposited at 450 C exhibited two transitions one near 50 C and the other near 60 C possibly related to the presence of other vanadium phases or of important stresses in them. Finally, the vanadium oxide thin films exhibited significant sensory capabilities decreasing their resistance in the presence of hydrogen gas with response times in the order of a few seconds and working temperature at 40 C. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. Molecular hydrogen in the z = 2.66 damped Lyman-alpha absorber toward Q J0643-5041

    Vásquez, D Albornoz; Noterdaeme, P; Petitjean, P; Srianand, R; Ledoux, C


    We use high signal-to-noise ratio, high-resolution VLT-UVES data of Q J0643-5041 amounting to a total of more than 23 hours exposure time and fit the neutral hydrogen, metals and H2 absorption features with multiple-component Voigt profiles. We study the relative populations of H2 rotational levels and the fine-structure excitation of neutral carbon to determine the physical conditions in the H2-bearing cloud. We find some evidence for part of the quasar broad line emission region not being fully covered by the H2-bearing cloud. We measure a total neutral hydrogen column density of log N(H) = 21.03 +/- 0.08. Molecular hydrogen is detected in several rotational levels, possibly up to J = 7, in a single component. The corresponding molecular fraction is log f = -2.19+0.07-0.08, where f = 2N(H2)/(2N(H2)+N(H)). The H2 Doppler parameter is of the order of 1.5 km/s for J = 0, 1 and 2 and larger for J>2. The molecular component has a kinetic temperature of T = 80 K, which yields a mean thermal velocity of about 1 km...

  16. Power Test of the Ladder IH-RFQ Accelerator at Peking University

    LU Yuan-Rong; CHEN Wei; NIE Yuan-Cun; LIU Ge; GAO Shu-Li; ZENG Hong-Jin; YAN Xue-Qing; CHEN Jia-Er


    A 104-MHz ladder interdigital-H radio frequency quadrupole accelerator (T-IH-RFQ) is developed for applying RFQs to heavy ion implantation and accelerator-based mass spectroscopy in recent years at the Institute of Heavy Ion Physics,Peking University.It could accelerate ions with a mass-to-charge ratio of less than 14,from 2.9 ke V/u to 35.7keV/u within a length of 1.1 m.The T-IH-RFQ cavity operating at H21(0) mode was constructed successfully.Based on a well designed rf power feeding system,the cavity was cold measured and tested with high rf power.In the case of cold measurement,the rf properties were obtained using a vector network analyzer with the help of a perturbation capacitor. During a high power test,the inter-electrode voltage was derived from the energy spectrum of x-rays measured by a high purity Ge detector.The results show that the specific shunt impedance of the T-IH-RFQ cavity reaches 178kΩm,which could meet the requirements of beam dynamics design.

  17. Kinetic stabilization and reactivity of π single-bonded species: effect of the alkoxy group on the lifetime of singlet 2,2-dialkoxy-1,3-diphenyloctahydropentalene-1,3-diyls.

    Nakagaki, Tomoyuki; Sakai, Tomoko; Mizuta, Tsutomu; Fujiwara, Yoshihisa; Abe, Manabu


    Kinetic stabilization and reactivity of π single-bonded species have been investigated in detail by generating a series of singlet 2,2-dialkoxy-1,3-diphenyloctahydropentalene-1,3-diyls (DRs). The lifetime at 293 K in benzene was found to increase when the carbon chain length of the alkoxy groups was increased; 292 ns (DRb; OR = OR' = OCH3) DRd; OR = OR' = OC3H7) ≈2292 ns (DRe; OR = OR' = OC6H13) ≈2146 ns (DRf; OR = OR' = OC10H21). DRh (OR = OC3H7, OR' = OCH3; 935 ns) with the mixed-acetal moiety is a longer-lived species than another diastereomer DRg (OR = OCH3, OR' = OC3H7; 516 ns). Activation parameters determined for the first-order decay process reveal that the enthalpy factor plays a crucial role in determining the energy barrier of the ring-closing reaction, that is, from the π-bonding to the σ-bonding compounds. Computational studies using density functional theory provided more insight into the structures of the singlet species with π single-bonded character and the transition states for the ring-closing reaction, thereby clarifying the role of the alkoxy group on the lifetime and the stereoselectivity of the ring-closing reaction. PMID:23787808

  18. Real Estate Taxes in Albania

    Luciana Koprencka


    Full Text Available The construction sector is one of the mainsectors of the Albanian economy, which,during the last 20 years, has experiencedthe greatest economic growth. In 1991 thissector has contributed by 2.5% to the GDP,in 2006 by 4.9%, while in 2008, this sectorhas contributed by 14.9% to the national GDP. The relevant legislation has played animportant role in the development of this sector. The applied laws have tried to maintainat low levels the real estate prices and totransform such a problematic sector, withreference to fiscal evasion and informality,into an easily controllable sector. The taxesapplied in the construction sector are the sameas in other economic sectors, although thetaxation management in the construction sector, except forthose common principles thatregulate the tax management in general, isbased on some specificrules related to thecharacteristics of this sector. Increase the level of taxation on the transfer of ownership tothe extent of 10%, paralyzed the housing market by reducing the number of sales,especially of real estate old, previously this was 0.3-5%of sales value.JEL Classification: H21

  19. Investigation of interaction between alkoxy substituted phthalocyanines with different lengths of alkyl residue and bovine serum albumin

    Interaction between bovine serum albumin and alkoxy substituted phthalocyanines was studied by means of electron absorption spectroscopy, fluorescence spectroscopy and viscosimetry. The binding constants and binding distance were calculated. It was found that ZnPc(4-NH-CO-C6H4-OC10H21)4 prevents twisting of BSA molecule and localizes between subdomains IB and IIA in protein globule. ZnPc(4-NH-CO-C6H4-OC6H13)4 and ZnPc(4-NH-CO-C6H4-OC8H17)4 are located on the outer surface of the protein globule. In the case of ZnPc(4-NH-CO-C6H4-OC3H7)4 it can be assumed that the phthalocyanine molecule is in the immediate vicinity of the subdomains IB and IIA. - Highlights: • Interaction between bovine serum albumin and alkoxy substituted phthalocyanines was studied by means of electron absorption spectroscopy, fluorescence spectroscopy and viscosimetry. • The binding constants and binding distance were calculated by using the Scatchard method. • Photochemical characteristics of phthalocyanines of studied phthalocyanines are defined. • Localization of phthalocyanines on the protein globule is defined

  20. Limits on the Size and Orbit Distribution of Main Belt Comets

    Sonnett, S; Jedicke, R; Masiero, J


    The seven known main belt comets (MBCs) have orbital characteristics of main belt asteroids yet exhibit dust ejection like comets. In order to constrain their physical and orbital properties we searched the Thousand Asteroid Light Curve Survey (TALCS; Masiero et al. 2009) for additional candidates using two diagnostics: tail and coma detection. This was the most sensitive MBC survey effort to date, extending the search from MBCs with H~18 (D~1 km) to H~21 (D~150 m). We fit each of the 924 TALCS objects to a PSF model incorporating both a coma and nuclear component to measure the fractional contribution of the coma to the total surface brightness. We determined the significance of the coma detection using the same algorithm on a sample of comparable null detections. We did not identify any MBC candidates with this technique to a sensitivity limit on the order of cometary mass loss rate of about 0.1 kg/s. Our tail detection algorithm identified statistically significant flux in a segmented annulus around the ca...

  1. XMM-Newton and UV Detection of OVIII and Broad HI absorption towards PKS 0558-504: a possible WHIM filament

    Nicastro, F; Fields, D; Conciatore, M L; Zappacosta, L; Elvis, M; Mathur, S; Papadakis, I


    We present the first likely X-ray detection associated with Broad HI Ly$\\beta$ (BLB) and Ly$\\alpha$ (BLA) absorbers, consistent with being a WHIM filament. The absorber lies along the line of sight to the nearby ($z=0.1372$) Seyfert 1 galaxy PKS 0558-504. The X-ray absorber is marginally detected in two independent XMM-Newton spectra of PKS 0558-504, with a combined single line statistical significance of 2.8$\\sigma$ (2.7$\\sigma$ and 1.2$\\sigma$ in the two spectra, respectively). When fitted with our self-consistent hybrid-photoionization WHIM models, the combined XMM-{\\em Newton} spectrum is consistent with the presence of an OVIII K$\\alpha$ absorber at $z=(0.117 \\pm 0.001)$, with log$T=6.56_{-0.17}^{+0.19}$ K, and logN$_H=(21.5 \\pm 0.3) (Z/Z_{0.01\\odot})^{-1}$ cm$^{-2}$. The lack of detection of associated OVI in the archival FUSE spectrum of PKS 0558-504, allows us to infer a tighter lower limit on the temperature, of log$T>6.52$ K (at 1$\\sigma$). The statistical sigificance of this single X-ray detection ...

  2. Distribution and Sources of Petroleum Hydrocarbons in Recent Sediments of the Imo River, SE Nigeria.

    Oyo-Ita, Inyang O; Oyo-Ita, Orok E; Dosunmu, Miranda I; Domínguez, Carmen; Bayona, Josep M; Albaigés, Joan


    The distribution of aliphatic and aromatic hydrocarbons in surface sediments of the lower course of the Imo River (Nigeria) was investigated to determine the sources and fate of these compounds. The aliphatic fraction is characterized by a widespread contribution of highly weathered/biodegraded hydrocarbon residues (reflected in the absence of prominent n-alkane peaks coupled with the presence of 17α(H),21β(H)-25-norhopane, an indicator of heavy hydrocarbon biodegradation) of Nigerian crude oils (confirmed by the occurrence of 18α(H)-oleanane, a compound characteristic of oils of deltaic origin). The concentrations of polycyclic aromatic hydrocarbons (PAHs) ranging from 48 to 117 ng/g dry weight (dw; ∑13PAHs) indicate a moderate pollution, possibly lowered by the sandy lithology and low organic carbon (OC) content of the sediments. Concentrations slightly decrease towards the estuary of the river, probably due to the fact that these stations are affected by tidal flushing of pollutants adsorbed on sediment particles and carried away by occasional storm to the Atlantic Ocean. A number of PAH ratios, including parent/alkylated and isomeric compounds, indicates a predominance of petrogenic sources, with a low contribution of pyrolytic inputs, particularly of fossil fuel combustion. On the basis of OC/ON (>10) and Per/ΣPAHpenta- (>10) values, a diagenetic terrigenous OC was proposed as a source of perylene to the river. PMID:26546420

  3. Virulence profiles of Shiga toxin-producing Escherichia coli and other potentially diarrheagenic E.coli of bovine origin, in Mendoza, Argentina

    M.A. Pizarro


    Full Text Available This study described a group of strains obtained from a slaughter house in Mendoza, in terms of their pathogenic factors, serotype, antibiotype and molecular profile. Ninety one rectal swabs and one hundred eight plating samples taken from carcasses of healthy cattle intended for meat consumption were analyzed. Both the swab and the plate samples were processed to analyze the samples for the presence of virulence genes by PCR: stx1, stx2, eae and astA. The Stx positive strains were confirmed by citotoxicity assay in Vero cells. The isolates were subsequently investigated for their O:H serotype, antimicrobial susceptibility and molecular profile by Random Amplification of Polymorphic DNA (RAPD. Twelve E.coli strains were identified by their pathogenicity. Nine were from fecal origin and three from carcasses. Three strains carried the stx1 gene, three the stx2 gene, two carried eae and four the astA gene. The detected serotypes were: O172:H-; O150:H8; O91:H21; O178:H19 and O2:H5. The strains showed a similarity around 70% by RAPD. Some of the E.coli strains belonged to serogroups known for certain life-threatening diseases in humans. Their presence in carcasses indicates the high probability of bacterial spread during slaughter and processing.

  4. Early development of Calanus hyperboreus nauplii: Response to a changing ocean

    Jung-Madsen, Signe; Nielsen, Torkel Gissel; Grønkjær, Peter;


    To forecast effects of temperature changes on recruitment and population dynamics of the Arctic copepod Calanus hyperboreus, laboratory experiments investigating temperature and food effects on early development were performed in Disko Bay, western Greenland, in 2009, and ascent rates of C...... hatching was fitted to a Beleˇhra´dek temperature function (r2 . 0.99) with mean development time (MDT) of eggs ranging from 2.8 to 5.8 d. MDT of fed and starved nauplii was calculated for nauplii raised at 5uC. Fed nauplii developed through the first five nauplius stages (N1–N5) during 40 d of incubation......, whereas development of starved nauplii ceased at N3. Nauplii were able to survive at least 30 d of starvation. Respiration rate was measured for N1 and N3 at 0uC, 5uC, and 10uC, and it increased with development stage and temperature from 0.05 6 0.01 to 0.29 6 0.08 nmol O2 nauplii21 h21 for N1 at 0uC and...

  5. Evaluation of biodiesel as bioremediation agent for the treatment of the shore affected by the heavy oil spill of the Prestige

    Fernandez-Alvarez, P. [Department of Chemical Engineering, School of Engineering, Avda. Lope Gomez de Marzoa, University of Santiago de Compostela, E-15782 Santiago de Compostela (Spain); Vila, J. [Department of Microbiology, Faculty of Biology, University of Barcelona, Diagonal 645, E-08028 Barcelona (Spain); Garrido, J.M. [Department of Chemical Engineering, School of Engineering, Avda. Lope Gomez de Marzoa, University of Santiago de Compostela, E-15782 Santiago de Compostela (Spain)]. E-mail:; Grifoll, M. [Department of Microbiology, Faculty of Biology, University of Barcelona, Diagonal 645, E-08028 Barcelona (Spain); Feijoo, G. [Department of Chemical Engineering, School of Engineering, Avda. Lope Gomez de Marzoa, University of Santiago de Compostela, E-15782 Santiago de Compostela (Spain); Lema, J.M. [Department of Chemical Engineering, School of Engineering, Avda. Lope Gomez de Marzoa, University of Santiago de Compostela, E-15782 Santiago de Compostela (Spain)


    The efficiency of different bioremediation products (nutrients, microorganisms and biodiesel) was tested using tiles located in both the supra-littoral and intertidal zones of a beach that was affected by the heavy oil spill of the Prestige. Neither nutrients nor microorganisms meant an improvement with respect to the natural processes. The addition of biodiesel improved the appearance of the treated tiles and apparently accelerated the degradation of the aliphatic and aromatic fractions of the residual fuel oil. Nevertheless, PAHs degradation was similar and very high in all the treatments (80-85% after 60 days). On the other hand, the evolution with time of the amount of vanadium was similar to that of 17{alpha}(H),21{beta}(H)-hopane, so it was concluded that vanadium could also be used to estimate the extent of oil degradation in the field. These results also suggested that the residual fuel oil mineralization was very low throughout 1 year in all the treatments. Moreover, the increase of the oxygen content of the residual oil from around 1% till 4-8% indicated that the partial oxidation of hydrocarbons took place, and that the hydrocarbon oxidation products accumulated in the polar fractions. In general, the results pointed out that bioremediation techniques were not suitable for the recovery of shores affected by heavy oil spills.

  6. Evaluation of biodiesel as bioremediation agent for the treatment of the shore affected by the heavy oil spill of the Prestige.

    Fernández-Alvarez, P; Vila, J; Garrido, J M; Grifoll, M; Feijoo, G; Lema, J M


    The efficiency of different bioremediation products (nutrients, microorganisms and biodiesel) was tested using tiles located in both the supra-littoral and intertidal zones of a beach that was affected by the heavy oil spill of the Prestige. Neither nutrients nor microorganisms meant an improvement with respect to the natural processes. The addition of biodiesel improved the appearance of the treated tiles and apparently accelerated the degradation of the aliphatic and aromatic fractions of the residual fuel oil. Nevertheless, PAHs degradation was similar and very high in all the treatments (80-85% after 60 days). On the other hand, the evolution with time of the amount of vanadium was similar to that of 17alpha(H),21beta(H)-hopane, so it was concluded that vanadium could also be used to estimate the extent of oil degradation in the field. These results also suggested that the residual fuel oil mineralization was very low throughout 1 year in all the treatments. Moreover, the increase of the oxygen content of the residual oil from around 1% till 4-8% indicated that the partial oxidation of hydrocarbons took place, and that the hydrocarbon oxidation products accumulated in the polar fractions. In general, the results pointed out that bioremediation techniques were not suitable for the recovery of shores affected by heavy oil spills. PMID:17360115

  7. Evaluation of biodiesel as bioremediation agent for the treatment of the shore affected by the heavy oil spill of the Prestige

    The efficiency of different bioremediation products (nutrients, microorganisms and biodiesel) was tested using tiles located in both the supra-littoral and intertidal zones of a beach that was affected by the heavy oil spill of the Prestige. Neither nutrients nor microorganisms meant an improvement with respect to the natural processes. The addition of biodiesel improved the appearance of the treated tiles and apparently accelerated the degradation of the aliphatic and aromatic fractions of the residual fuel oil. Nevertheless, PAHs degradation was similar and very high in all the treatments (80-85% after 60 days). On the other hand, the evolution with time of the amount of vanadium was similar to that of 17α(H),21β(H)-hopane, so it was concluded that vanadium could also be used to estimate the extent of oil degradation in the field. These results also suggested that the residual fuel oil mineralization was very low throughout 1 year in all the treatments. Moreover, the increase of the oxygen content of the residual oil from around 1% till 4-8% indicated that the partial oxidation of hydrocarbons took place, and that the hydrocarbon oxidation products accumulated in the polar fractions. In general, the results pointed out that bioremediation techniques were not suitable for the recovery of shores affected by heavy oil spills

  8. A field demonstration of the efficacy of bioremediation to treat oiled shorelines following the Sea Empress incident

    Bioremediation was investigated as a method of treating a mixture of Forties Crude Oil and Heavy Fuel Oil stranded on Bullwell Bay, Milford Haven, UK after the grounding of the Sea Empress in 1996. A randomised block design in triplicate was used to test the efficacy of two bioremediation treatments: a weekly application of mineral nutrient dissolved in sea water and a single application of a slow-release fertiliser. Each treatment supplied an equivalent amount of nitrogen and phosphorus. Concentrations of residual hydrocarbon normalised to the biomarker 17α(H),21β(H)-hopane showed that after two months the oil was significantly (p<0.001) more biodegraded in the treated plots than in the controls. On average, the oil in the nutrient amended plots was 37% more degraded than that found in the controls. There was no evidence that the bioremediation treatment increased the toxicity of the oiled sediment. The results confirm that bioremediation can be used to treat a mixture of crude and heavy fuel oil on a pebble beach. In particular, the data suggest that the application of a slow-release fertiliser alone may be a cost-effective method of treating low-energy, contaminated shorelines after a spill incident. (Author)

  9. μ3-Iodo-tri-μ3-sulfido-sulfidotris[tris(4-methoxyphenylphosphine-κP]tricopper(Itungsten(VI N,N-dimethylformide solvate

    Guodong Tang


    Full Text Available A new W/S/Cu cluster, [Cu3WIS4(C21H21O3P3]·C3H7NO, was formed by the reaction of ammonium tetrathiotungstate(VI, cuprous iodide and tris(4-methoxyphenylphosphine in N,N-dimethylformamide. The title compound exhibits a heavily distorted cubane-like skeleton in which the average Cu—I, Cu—S and W—μ3-S distances are 2.934, 2.302 and 2.249 Å, respectively. The W atom exhibits tetrahedral geometry, formed by three μ3-S and one terminal S atom; the W—S(terminal bond length is 2.1426 (13 Å. Each Cu atom is coordinated by one P atom from a tris(4-methoxyphenylphosphine (mop, two μ3-S and one μ3-I atom, forming a distorted tetrahedral coordination geometry. Some of the mop ligand methyl groups have large librations. Together with the three neutral mop ligands, the title compound is neutral; this contrasts with the all-halogen-coordinated Mo/S/Ag clusters with the same structure, which carry negative charge.

  10. Crystal structures of (E-3-(furan-2-yl-2-phenyl-N-tosylacrylamide and (E-3-phenyl-2-(m-tolyl-N-tosylacrylamide

    Dong Cheng


    Full Text Available In the title N-tosylacrylamide compounds, C20H17NO4S, (I, and C23H21NO3S, (II, the conformation about the C=C bond is E. The acrylamide groups, [–NH—C(=O—C=C–], are almost planar, with the N—C—C=C torsion angle being −170.18 (14° in (I and −168.01 (17° in (II. In (I, the furan, phenyl and 4-methylbenzene rings are inclined to the acrylamide mean plane by 26.47 (11, 69.01 (8 and 82.49 (9°, respectively. In (II, the phenyl, 3-methylbenzene and 4-methylbenzene rings are inclined to the acrylamide mean plane by 11.61 (10, 78.44 (10 and 78.24 (10°, respectively. There is an intramolecular C—H...π interaction present in compound (II. In the crystals of both compounds, molecules are linked by pairs of N—H...O hydrogen bonds, forming inversion dimers with an R22(8 ring motif. In (I, the dimers are reinforced by C—H...O hydrogen bonds and linked by C—H...π interactions, forming chains along [011]. In the crystal of (II, the dimers are linked via C—H...O hydrogen bonds, forming chains along [100]. The chains are further linked by C—H...π interactions, forming layers parallel to (010.

  11. Crystal structures of four indole derivatives with a phenyl substituent at the 2-position and a carbonyl group at the 3-position: the C(6 N—H...O chain remains the same, but the weak reinforcing interactions are different

    Jamie R. Kerr


    Full Text Available We describe the crystal structures of four indole derivatives with a phenyl ring at the 2-position and different carbonyl-linked substituents at the 3-position, namely 1-(2-phenyl-1H-indol-3-ylethanone, C16H13NO, (I, 2-cyclohexyl-1-(2-phenyl-1H-indol-3-ylethanone, C22H23NO, (II, 3,3-dimethyl-1-(2-phenyl-1H-indol-3-ylbutan-1-one, C20H21NO, (III, and 3-benzoyl-2-phenyl-1H-indole, C21H15NO, (IV. In each case, the carbonyl-group O atom lies close to the indole-ring plane and points towards the benzene ring. The dihedral angles between the indole ring system and 2-phenyl ring for these structures are clustered in a narrow range around 65°. The dominant intermolecular interaction in each case is an N—H...O hydrogen bond, which generates a C(6 chain, although each structure possesses a different crystal symmetry. The C(6 chains are consolidated by different (C—H...O, C—H...π and π–π stacking weak interactions, with little consistency between the structures.

  12. (E-N-(4-{[1-(Prop-2-en-1-yl-1H-1,2,3-triazol-4-yl]methoxy}benzylidenemorpholin-4-amine

    Mehmet Akkurt


    Full Text Available The asymmetric unit of the title compound, C17H21N5O2, contains two crystallographically independent molecules, which are linked by a C—H...N hydrogen bond. The morpholine rings of both molecules adopt distorted chair conformations. The dihedral angles between the triazole and benzene rings are 12.8 (3° in the first independent molecule in which the –N=C– group between the morpholine and benzene rings is disordered [site-occupancy ratio = 0.576 (7:0.424 (7] and 88.1 (2° in the second independent molecule. In the crystal, molecules are linked by C—H...N hydrogen bonds along the [100] direction. In addition, one weak C—H...π interaction and two weak π–π stacking interactions [centroid–centroid distances = 3.840 (3 and 3.823 (2 Å] between the triazole rings of adjacent molecules are observed. The atoms of the terminal propenyl groups in both molecules are disordered over two sets of sites [site-occupancy ratios = 0.691 (10:0.309 (10 and 0.705 (15:0.295 (15].

  13. Molecular formula analysis of fragment ions by isotope-selective collision-induced dissociation tandem mass spectrometry of pharmacologically active compounds.

    Bianco, Giuliana; Buchicchio, Alessandro; Lelario, Filomena; Cataldi, Tommaso R I


    The purpose of this work is to explore the mass fragment characterization of commonly used drugs through a novel approach, which involves isotope-selective tandem mass spectrometry (MS/MS). Collision-induced dissociation (CID) was performed with a low-resolution linear ion trap mass spectrometer in positive electrospray ionization. Three pharmacologically active ingredients, i.e. omeprazole, meloxicam and brinzolamide, selected as model compounds in their own formulation, were investigated as a sodiated adduct [C17 H19 N3 O3 S + Na](+) (omeprazole) and as protonated adducts, [C14 H13 N3 O4 S2  + H](+) and [C12 H21 N3 O5 S3  + H](+) , meloxicam and brinzolamide, respectively. Selecting a narrow window of ±0.5 m/z units, precursor ion fragmentation by CID-MS/MS of isotopologues A + 0, A + 1 and A + 2 was found very useful to confirm the chemical formula of product ions, thus aiding the establishment of characteristic fragmentation pathways of all three examined compounds. The correctness of putative molecular formula of product ions was easily demonstrated by exploiting the isotope peak abundance ratios (i.e. IF+0 /IF+1 and IF+0 /IF+2 ) as simple constraints in low-resolution MS instrumentations. PMID:25476951

  14. Species and serovars of enteropathogenic agents associated with acute diarrheal disease in Rosario, Argentina Espécies e serovariantes de agentes enteropatogênicos associados com diarréia aguda em Rosario, Argentina

    Rodolfo Notario


    Full Text Available We report the most frequent species and serovars of enteropathogenic organisms in Rosario from 1985 to 1993. Enteropathogenic Escherichia coli was the most prevalent agent affecting 144/570 (25.2% children; 0111 represented 41.8%, 055: 13.6%, 0119: 12.7%. Among enterotoxigenic E. coli (ETEC the most frequent were ETEC-ST 0128:H21 and 0153:H45. Shigella spp were isolated in 8.8%; S.flexneri: 7%, principally type 2 (59.5%; S. sonnei: 1.6%, and S. dysenteriae type 2: 0.2%. Campylobacter spp were found in 6.1% of patients; C.jejuni: 4.6%; C. coli: 1.4% and C. lari: 0.2%; except groups 0 13,50 and 0 4 (2 cases each, no predominant serogroups were found. Salmonella was isolated in 2.8% of cases, being the predominant serovar S. typhimurium until 1986, but a dramatically increase of cases due to S. enteritidis was observed since 1987. There was 1.9% of Aeromonas spp and 2 cases due to Vibrio cholerae non 0-1. No Yersinia was found. In patients with gastroenteritis due to Shigella, Campylobacter, Salmonella, or EPEC as the unique pathogen, leukocytes were observed in the faeces in 70%, 50%, 20%, and 10% of cases respectively.Apresentamos as espécies e serovars mais frequentes dos microorganismos enteropatógenos entre 1985 e 1990 em Rosario. Escherichia coli enteropatogênica (EPEC foi a que predominou, afetando 144/570 (25,2% crianças; 0111 representou 41,8%, 055 13,6%, 0119 12,7%. Entre as E. coli enterotoxigênicas (ETEC, ETEC-ST 0128:H21 e 0153:H45 foram as mais frequentes. Entre os 570 pacientes, Shigella spp. foi diagnosticada em 50 (8,8%; S. flexneri 7%, principalmente do tipo 2 (59,5%, S. sonnei 1,6% e S. dysenteriae tipo 2 (1%. Foram encontrados Campylobacter spp em 6,1% dos pacientes; C. jejuni 4,6%, C. coli 1,4% e C. lari 0,2%; exceto os grupos 0 13/50 e 0 4 (dois de cada um, não foram encontrados serogrupos predominantes. Salmonella foi encontrada em 2,8% dos casos, sendo o serovar S. typhimurium o predominante até 1986, mas desde 1987

  15. Assessment of extreme quantitative precipitation forecasts and development of regional extreme event thresholds using data from HMT-2006 and COOP observers

    Ralph, F.M.; Sukovich, E.; Reynolds, D.; Dettinger, M.; Weagle, S.; Clark, W.; Neiman, P.J.


    Extreme precipitation events, and the quantitative precipitation forecasts (QPFs) associated with them, are examined. The study uses data from the Hydrometeorology Testbed (HMT), which conducted its first field study in California during the 2005/06 cool season. National Weather Service River Forecast Center (NWS RFC) gridded QPFs for 24-h periods at 24-h (day 1), 48-h (day 2), and 72-h (day 3) forecast lead times plus 24-h quantitative precipitation estimates (QPEs) fromsites in California (CA) and Oregon-Washington (OR-WA) are used. During the 172-day period studied, some sites received more than 254 cm (100 in.) of precipitation. The winter season produced many extreme precipitation events, including 90 instances when a site received more than 7.6 cm (3.0 in.) of precipitation in 24 h (i.e., an "event") and 17 events that exceeded 12.7 cm (24 h)-1 [5.0 in. (24 h)-1]. For the 90 extreme events f.7.6 cm (24 h)-1 [3.0 in. (24 h)-1]g, almost 90% of all the 270 QPFs (days 1-3) were biased low, increasingly so with greater lead time. Of the 17 observed events exceeding 12.7 cm (24 h)-1 [5.0 in. (24 h)-1], only 1 of those events was predicted to be that extreme. Almost all of the extreme events correlated with the presence of atmospheric river conditions. Total seasonal QPF biases for all events fi.e., $0.025 cm (24 h)-1 [0.01 in. (24 h)-1]g were sensitive to local geography and were generally biased low in the California-Nevada River Forecast Center (CNRFC) region and high in the Northwest River Forecast Center(NWRFC) domain. The low bias in CA QPFs improved with shorter forecast lead time and worsened for extreme events. Differences were also noted between the CNRFC and NWRFC in terms of QPF and the frequency of extreme events. A key finding from this study is that there were more precipitation events .7.6 cm (24 h)-1 [3.0 in. (24 h)21] in CA than in OR-WA. Examination of 422 Cooperative Observer Program (COOP) sites in the NWRFC domain and 400 in the CNRFC domain

  16. Influência do período de alimentação no consumo e ganho de peso do pirarucu Influence of feeding period on consumption and weight gain of pirarucu

    Roger Crescêncio


    Full Text Available O objetivo deste trabalho foi verificar o período preferencial de consumo alimentar do pirarucu, Arapaima gigas, e a influência de diferentes turnos de alimentação no consumo e ganho de peso dessa espécie. Foram testados três tratamentos: alimentação diurna (peixes alimentados às 9h e 15h, alimentação noturna (peixes alimentados às 21h e 3h e alimentação contínua (peixes alimentados às 9h, 15h, 21h e 3h. Cada tratamento foi avaliado em triplicata, com cada unidade experimental formada por oito peixes, com peso médio de 313 g, estocados em tanques-redes de 1 m³ (1x1x1 m. Os nove tanques-redes foram alocados em um viveiro escavado de 120 m². O experimento durou 60 dias. A alimentação contínua promoveu maiores ganhos de peso e biomassa, taxa de crescimento específico e consumo total. Os tratamentos alimentação diurna e alimentação noturna apresentaram ganho de peso semelhante, porém, a alimentação diurna apresentou a melhor conversão alimentar. O período preferencial de alimentação do pirarucu foi o noturno, principalmente no começo da noite. Os dados deste estudo indicam que o horário de preferência alimentar não é o melhor horário de alimentação do pirarucu, em uma criação comercial. O período de alimentação mais indicado para a espécie, baseado na capacidade de conversão alimentar, é o diurno.The objective of this study was to verify pirarucu Arapaima gigas preferential time of feeding, and the influence of different feeding periods on consumption and weight gain of this species. Three treatments were tested: diurnal feeding (fish fed at 9h and 15h, nocturnal feeding (fish fed at 21h and 3h, and continuous feeding (fish fed at 9h, 15h, 21h and 3h. Each treatment was evaluated in triplicate, and each trial unit had eight fishes with 313 g average weight, stoked into a 1 m³ (1x1x1 m net cage. The nine net cages were located on a 120 m² earth pond. The trial lasted for 60 days. Continuous feeding

  17. η Carinae Baby Homunculus uncovered by ALMA

    Abraham, Zulema; Beaklini, Pedro P. B. [Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Universidade de São Paulo, R. do Matão 1226, Cidade Universitária, CEP 05508-900 São Paulo, SP (Brazil); Falceta-Gonçalves, Diego, E-mail: [Escola de Artes, Ciências e Humanidades, Universidade de São Paulo, R. Arlindo Bettio 1000, 03828-000 São Paulo, SP (Brazil)


    We report observations of η Carinae obtained with ALMA in the continuum of 100, 230, 280, and 660 GHz in 2012 November, with a resolution that varied from 2.''88 to 0.''45 for the lower and higher frequencies, respectively. The source is not resolved, even at the highest frequency; its spectrum is characteristic of thermal bremsstrahlung of a compact source, but different from the spectrum of optically thin wind. The recombination lines H42α, He42α, H40α, He40α, H50β, H28α, He28α, H21α, and He21α were also detected, and their intensities reveal non-local thermodynamic equilibrium effects. We found that the line profiles could only be fit by an expanding shell of dense and ionized gas, which produces a slow shock in the surroundings of η Carinae. Combined with fittings to the continuum, we were able to constrain the shell size, radius, density, temperature, and velocity. The detection of the He recombination lines is compatible with the high-temperature gas and requires a high-energy ionizing photon flux, which must be provided by the companion star. The mass-loss rate and wind velocity, necessary to explain the formation of the shell, are compatible with an luminous blue variable eruption. The position, velocity, and physical parameters of the shell coincide with those of the Weigelt blobs. The dynamics found for the expanding shell correspond to matter ejected by η Carinae in 1941 in an event similar to that which formed the Little Homunculus; for that reason, we called the new ejecta the 'Baby Homunculus'.

  18. Protection against Shiga-Toxigenic Escherichia coli by Non-Genetically Modified Organism Receptor Mimic Bacterial Ghosts.

    Paton, Adrienne W; Chen, Austen Y; Wang, Hui; McAllister, Lauren J; Höggerl, Florian; Mayr, Ulrike Beate; Shewell, Lucy K; Jennings, Michael P; Morona, Renato; Lubitz, Werner; Paton, James C


    Shiga-toxigenic Escherichia coli (STEC) causes severe gastrointestinal infections in humans that may lead to life-threatening systemic sequelae, such as the hemolytic uremic syndrome (HUS). Rapid diagnosis of STEC infection early in the course of disease opens a window of opportunity for therapeutic intervention, for example, by administration of agents that neutralize Shiga toxin (Stx) in the gut lumen. We previously developed a recombinant bacterium that expresses a mimic of the Stx receptor globotriaosyl ceramide (Gb3) on its surface through modification of the lipopolysaccharide (A. W. Paton, R. Morona, and J. C. Paton, Nat Med 6:265-270, 2000, This construct was highly efficacious in vivo, protecting mice from otherwise fatal STEC disease, but the fact that it is a genetically modified organism (GMO) has been a barrier to clinical development. In the present study, we have overcome this issue by development of Gb3 receptor mimic bacterial ghosts (BGs) that are not classified as GMOs. Gb3-BGs neutralized Stx1 and Stx2 in vitro with high efficiency, whereas alternative Gb3-expressing non-GMO subbacterial particles (minicells and outer membrane blebs) were ineffective. Gb3-BGs were highly efficacious in a murine model of STEC disease. All mice (10/10) treated with Gb3-BGs survived challenge with a highly virulent O113:H21 STEC strain and showed no pathological signs of renal injury. In contrast, 6/10 mice treated with control BGs succumbed to STEC challenge, and survivors exhibited significant weight loss, neutrophilia, and histopathological evidence of renal damage. Thus, Gb3-BGs offer a non-GMO approach to treatment of STEC infection in humans, particularly in an outbreak setting. PMID:26099582

  19. Differential Expression of Three Hypoxia-inducible Factor-α Subunits in Pulmonary Arteries of Rat with Hypoxia-induced Hypertension

    Qi-Fang LI; Ai-Guo DAI


    Hypoxia inducible transcription factor (HIF)-1α plays an important role in the development of hypoxic pulmonary hypertension, but little is known about HIF-2α and HIF-3α with respect to transcriptional regulation by hypoxia. To examine the expression patterns of all HIF-α subunits (HIF-1α, HIF-2α and HIF-3α) in pulmonary arteries of rats undergoing systemic hypoxia, five groups of healthy male Wistar rats were exposed to normoxia (N) and hypoxia for 3 (H3), 7 (H7), 14 (H14) and 21 (H21) d respectively. Mean pulmonary arterial pressure (mPAP), vessel morphometry and right ventricular hypertrophy index were measured. Lungs were inflation fixed for immunohistochemistry and in situ hybridization, and homogenized for Western blot. mPAP increased significantly after 7 d of hypoxia [(18.4±0.4) vs. (14.4±0.4) mmHg, H7 vs.N], reached its peak after 14 d of hypoxia, then remained stable. Pulmonary artery remodeling and right ventricular hypertrophy developed significantly after 14 d of hypoxia. During normoxia, HIF-1 α and HIF-3α staining were slightly positive regarding mRNA levels. A substantial alteration of HIF-1 α and HIF-3α staining occurred in pulmonary arteries after 14 d and 7 d of hypoxia, respectively, but HIF-2α stainin g showed an inversed trend after 14 d of hypoxia. Protein levels of all HIF-α subunits except HIF-3α showed a marked increase corresponding to the duration of hypoxia, which was obtained by Western blot. Our study found that HIF-1 α, HIF-2α and HIF-3α may not only confer different target genes, but also play key pathogenetic roles in hypoxic-induced pulmonary hypertension.

  20. Involvement of the nervous system following experimental infection with Pasteurella multocida B:2 in buffalo (Bubalus bubalis): A clinicopathological study.

    Marza, Ali Dhiaa; Jesse, Faez Firdaus Abdullah; Ahmed, Ihsan Muneer; Teik Chung, Eric Lim; Ibrahim, Hayder Hamzah; Zamri-Saad, Mohd; Omar, Abdul Rahman; Abu Bakar, Md Zuki; Saharee, Abdul Aziz; Haron, Abdul Wahid; Alwan, Mohammed Jwaid; Mohd Lila, Mohd Azmi


    Haemorrhagic septicaemia (HS) is an acute, fatal, septicaemic disease of cattle and buffaloes caused by one of two specific serotypes of Pasteurella multocida B:2 and E:2 in Asian and African, respectively. It is well known that HS affect mainly the respiratory and digestive tracts. However, involvement of the nervous system in pathogenesis of HS has been reported in previous studies without details. In this study, nine buffalo calves of 8 months old were distributed into three groups. Animals of Group 1 and 2 were inoculated orally and subcutaneously with 10 ml of 1 × 10(12) cfu/ml of P. multocida B:2, respectively, while animals of Group 3 were inoculated orally with 10 ml of phosphate buffer saline as a control. All calves in Group 1 and Group 3 were euthanised after 504 h (21 day) post-infection, while calves in Group 2 had to euthanise after 12 h post-infection as they develop sever clinical signs of HS. Significant differences were found in Group 2 in the mean scores of clinical signs, gross and histopathological changes which mainly affect different anatomic regions of the nervous system. In addition, successful bacterial isolation of P. multocida B:2 were obtained from different sites of the nervous system. On the other hand, less sever, clinical, gross and histopathological changes were found in Group 1. These results provide for the first time strong evidence of involving of the nervous system in pathogenesis of HS, especially in the peracute stage of the disease. PMID:26850845

  1. Analysis of petroleum hydrocarbons in soil from view of bioremediation process

    The pollution of the environment by petroleum hydrocarbons is the most often pollution of them all. Nevertheless, hydrocarbons present in environment can be not only of petroleum or anthropogenic origin, but of biogenic as well. Typically the hydrocarbons are presented in the environment as very complex mixtures of individual compounds with very different chemical structure, wide range of the boiling points (∼800 0C) as well as with the wide range of the number of carbon atoms. Immediately they are spread in any environmental matrix the complex physical, chemical and biochemical reactions start. A lot of methods have been developed and new are permanently in progress for the monitoring and control of petroleum hydrocarbons contamination and/or soils bioremediation. Generally, all methods by whose the hydrocarbons contaminants are determined in GC-FID system do not satisfied recommendations for enough accurate and precise results. Hyphenation of capillary gas chromatography and mass selective detector operated in the selective ion monitoring mode essentially allows detailed specification of non-polar extractable hydrocarbons. Isoprenoid alkanes, alkylhomologues of aromatic hydrocarbons and polycyclic alkanes hopanes-like were investigated as markers for recognition of petroleum and biogenic contamination. C3017α(H)21β(H)-hopane (C30-hopane) seems to be a suitable marker to identify hydrocarbons origin, to determine composting rates for nonpolar extractable compounds and to calculate real content of non-polar extractable compounds in final composting status on the assumption that the contamination is of mineral oil type. This is the survey into the results obtained in this field published in the literature as well as reached in our laboratory. (author)

  2. New branching rules induced by plethysm

    We derive group branching laws for formal characters of subgroups Hπ of GL(n) leaving invariant an arbitrary tensor Tπ of Young symmetry type π where π is an integer partition. The branchings GL(n) ↓ GL(n-1), GL(n) ↓ O(n) and GL(2n) ↓ Sp(2n) fixing a vector vi, a symmetric tensor gij = gji and an antisymmetric tensor fij = -fji, respectively, are obtained as special cases. All new branchings are governed by Schur function series obtained from plethysms of the Schur function sπ ≡ {π} by the basic M series of complete symmetric functions and the L = M-1 series of elementary symmetric functions. Our main technical tool is that of Hopf algebras and our main result is the derivation of a coproduct for any Schur function series obtained by plethysm from another such series. Therefrom one easily obtains π-generalized Newell-Littlewood formulae and the algebra of the formal group characters of these subgroups is established. Concrete examples and extensive tabulations are displayed for H13, H21 and H3, showing their involved and nontrivial representation theory. The nature of the subgroups is shown to be in general affine and in some instances non-reductive. We discuss the complexity of the coproduct formula and give a graphical notation to cope with it. We also discuss the way in which the group branching laws can be reinterpreted as twisted structures deformed by highly nontrivial 2-cocycles. The algebra of subgroup characters is identified as a cliffordization of the algebra of symmetric functions for GL(n) formal characters. Modification rules are beyond the scope of the present paper, but are briefly discussed

  3. An Experimental Field Dataset with Buoyant, Neutral, and Dense Gas Atmospheric Releases and Model Comparisons in Low-Wind Speed (Diffusion) Conditions

    Veronica E. Wannberg, Gustavious Williams, Patrick Sawyer, and Richard Venedam


    Aunique field dataset from a series of low–wind speed experiments, modeling efforts using three commonly used models to replicate these releases, and statistical analysis of how well these models were able to predict the plume concentrations is presented. The experiment was designed to generate a dataset to describe the behavior of gaseous plumes under low-wind conditions and the ability of current, commonly used models to predict these movements. The dataset documents the release and transport of three gases: ammonia (buoyant), ethylene (neutral), and propylene (dense) in low–wind speed (diffusion) conditions. Release rates ranged from 1 to 20 kg h21. Ammonia and ethylene had five 5-min releases each to represent puff releases and five 20-min releases each to represent plume releases. Propylene had five 5-min puffs, six 20-min plumes, and a single 30-min plume. Thirty-two separate releases ranging from 6 to 47 min were conducted, of which only 30 releases generated useful data. The data collected included release rates, atmospheric concentrations to 100 m from the release point, and local meteorological conditions. The diagnostics included nine meteorological stations on 100-m centers and 36 photoionization detectors in a radial pattern. Three current stateof- the-practice models, Aerial locations of Hazardous Atmospheres (ALOHA), Emergency Prediction Information code (EPIcode), and Second-Order Closure Integrated Puff (SCIPUFF), were used to try to duplicate the measured field results. Low wind speeds are difficult to model, and all of the models had difficulty replicating the field measurements. However, the work does show that these models, if used correctly, are conservative (overpredict concentrations) and can be used for safety and emergency planning.

  4. In-stream attenuation of neuro-active pharmaceuticals and their metabolites

    Writer, Jeffrey; Antweiler, Ronald C.; Ferrar, Imma; Ryan, Joseph N.; Thurman, Michael


    In-stream attenuation was determined for 14 neuro-active pharmaceuticals and associated metabolites. Lagrangian sampling, which follows a parcel of water as it moves downstream, was used to link hydrological and chemical transformation processes. Wastewater loading of neuro-active compounds varied considerably over a span of several hours, and thus a sampling regime was used to verify that the Lagrangian parcel was being sampled and a mechanism was developed to correct measured concentrations if it was not. In-stream attenuation over the 5.4-km evaluated reach could be modeled as pseudo-first-order decay for 11 of the 14 evaluated neuro-active pharmaceutical compounds, illustrating the capacity of streams to reduce conveyance of neuro-active compounds downstream. Fluoxetine and N-desmethyl citalopram were the most rapidly attenuated compounds (t1/2 = 3.6 ± 0.3 h, 4.0 ± 0.2 h, respectively). Lamotrigine, 10,11,-dihydro-10,11,-dihydroxy-carbamazepine, and carbamazepine were the most persistent (t1/2 = 12 ± 2.0 h, 12 ± 2.6 h, 21 ± 4.5 h, respectively). Parent compounds (e.g., buproprion, carbamazepine, lamotrigine) generally were more persistent relative to their metabolites. Several compounds (citalopram, venlafaxine, O-desmethyl-venlafaxine) were not attenuated. It was postulated that the primary mechanism of removal for these compounds was interaction with bed sediments and stream biofilms, based on measured concentrations in stream biofilms and a column experiment using stream sediments.

  5. The role of atomic hydrogen and hydrogen-induced martensites in hydrogen embrittlement of type 304L stainless steel

    潘川; 褚武扬; 李正邦; 梁东图; 宿彦京; 乔利杰


    The role of atomic hydrogen and hydrogen-induced martensites in hydrogen embrittlement in slow strain rate tensile tests and hydrogen-induced delayed cracking (HIC) in sustained load tests for type 304 L stainless steel was quantitatively studied.The results indicated that hydrogen-induced martensites formed when hydrogen concentration C0 exceeded 30 ppm,and increased with an increase in C0,i.e.M(vol%)=62-82.5exp(-C0/102).The relative plasticity loss caused by the martensites increased linearly with increasing amount of the martensites,i.e.Iδ(M),%=0.45M(vol %)=27.9-37.1 exp(-C0/102).The plasticity loss caused by atomic hydrogen Iδ(H) increased with an increase in C0 and reached a saturation value Iδ(H)max=40% when C0>100 ppm.Iδ(H) decreased with an increase in strain rate ,i.e.Iδ(H),%=-21.9-9.9,and was zero when ≥c=0.032/s.HIC under sustained load was due to atomic hydrogen,and the threshold stress intensity for HIC decreased linearly with lnC0,i.e.KIH(Mpam1/2)=91.7-10.1 lnC0(ppm).The fracture surface of HIC was dimple if KI was high or/and C0 was low,otherwise it was quasi-cleavage.The boundary line between ductile and brittle fracture surface was KI-54+25exp(-C0/153)=0.``

  6. Impact of Sulfuric Acid Treatment of Halloysite on Physico-Chemic Property Modification

    Tayser Sumer Gaaz


    Full Text Available Halloysite (HNT is treated with sulfuric acid and the physico-chemical properties of its morphology, surface activity, physical and chemical properties have been investigated when HNT is exposed to sulfuric acid with treatment periods of 1 h (H1, 3 h (H3, 8 h (H8, and 21 h (H21. The significance of this and similar work lies in the importance of using HNT as a functional material in nanocomposites. The chemical structure was characterized by Fourier transform infrared spectroscopy (FTIR. The spectrum demonstrates that the hydroxyl groups were active for grafting modification using sulfuric acid, promoting a promising potential use for halloysite in ceramic applications as filler for novel clay-polymer nanocomposites. From the X-ray diffraction (XRD spectrum, it can be seen that the sulfuric acid breaks down the HNT crystal structure and alters it into amorphous silica. In addition, the FESEM images reveal that the sulfuric acid treatment dissolves the AlO6 octahedral layers and induces the disintegration of SiO4 tetrahedral layers, resulting in porous nanorods. The Bruncher-Emmett-Teller (BET surface area and total pore volume of HNTs showed an increase. The reaction of the acid with both the outer and inner surfaces of the nanotubes causes the AlO6 octahedral layers to dissolve, which leads to the breakdown and collapse of the tetrahedral layers of SiO4. The multi-fold results presented in this paper serve as a guide for further HNT functional treatment for producing new and advanced nanocomposites.

  7. MAD about the Large Magellanic Cloud. Preparing for the era of Extremely Large Telescopes

    Fiorentino, G.; Tolstoy, E.; Diolaiti, E.; Valenti, E.; Cignoni, M.; Mackey, A. D.


    We present J,H,Ks photometry from the the Multi conjugate Adaptive optics Demonstrator (MAD), a visitor instrument at the VLT, of a resolved stellar population in a small crowded field in the bar of the Large Magellanic Cloud near the globular cluster NGC 1928. In a total exposure time of 6, 36 and 20 min, magnitude limits were achieved of J ~ 20.5 mag, H ~ 21 mag, and Ks ~ 20.5 mag respectively, with S/N > 10. This does not reach the level of the oldest Main Sequence Turnoffs, however the resulting Colour-Magnitude Diagrams are the deepest and most accurate obtained so far in the infrared for the LMC bar. We combined our photometry with deep optical photometry from the Hubble Space Telescope/Advanced Camera for Surveys, which is a good match in spatial resolution. The comparison between synthetic and observed CMDs shows that the stellar population of the field we observed is consistent with the star formation history expected for the LMC bar, and that all combinations of IJHKs filters can, with some care, produce the same results. We used the red clump magnitude in Ks to confirm the LMC distance modulus as, μ0 = 18.50 ± 0.06r ± 0.09s mag. We also addressed a number of technical aspects related to performing accurate photometry with adaptive optics images in crowded stellar fields, which has implications for how we should design and use the Extremely Large Telescopes of the future for studies of this kind. Based on observations obtained with the MCAO Demonstrator (MAD) al the VLT Melipal Nasmyth focus (ESO public data release).

  8. Induction and regulation of mRNA encoding 26-kDa protein in human cell lines treated with recombinant human tumor necrosis factor

    A 26-kDa protein, originally described in human fibroblasts superinduced for interferon β (IFN-β) production, and termed IFN-β2 by other investigators, is induced by cycloheximide and by a 22-kDa, interleukin 1 (IL-1)-related factor. Although the structure and sequence of the corresponding gene show nonhomology with the IFN-β gene, the gene is identical to that of B-cell stimulatory factor 2, a human interleukin, and displays a very potent growth and differentiation factor activity for B lymphocytes. In this work the authors show that IL-1β and tumor necrosis factor (TNF) strongly induce the 26-kDa protein in FS-4 fibroblasts and in some transformed cell lines. Addition of cycloheximide to recombinant (r)IL-1β and rTNF further enhances the level of 26-kDa-protein mRNA. They determined the kinetics of induction and the amounts of rTNF and rIL-1β required for optimal induction of this mRNA in FS-4 cells and in HeLa H21 cells and found that rIL-1β is more efficient inducer of 26-kDa protein mRNA than is TNF. By analyzing the inducibility of the 26-kDa protein gene by rTNF and rIL-1β in a series of transformed cell lines that differ in their sensitivity to the cytotoxic action of TNF, they report a direct correlation between the 26-kDa protein mRNA expression and the resistance of these cells to the cytotoxic effect of TNF


    Ronald Huarachi


    Full Text Available The aim of this study was to use Hydra vulgaris Pallas, 1766 (Hydrozoa: Hydridae as a bioindicator of water quality of the Chili River, Arequipa, Peru. The freshwater hydra were collected in the spring "Ojo del Milagro", Characato District, Arequipa, Peru. H. vulgaris was cultivated under standardized conditions and were fed Artemia sp. K2Cr2O7 was used as a positive control and as a reference toxin. Acute toxicity and morphological changes of H. vulgaris were evaluated on Tiabaya and Tingo, sampling points of the Chili River. The LC50 (median lethal concentration showed: Tingo (LC50-96h = 135.95% classifying it as non-toxic and Tiabaya (LC50 -24h = 61.83%, classifying it as moderately toxic; LC50-48h = 44.19% and LC50 -72h = 38.28% classifying them as toxic; LC50 -96h = 21.44% rating it as very toxic. Significant differences in the morphological changes of H. vulgaris were observed with regard to different concentrations and exposure time in waters sampled from Tingo from 48 h to 96 h and in Tiabaya, significant differences in morphological changes from 24 h to 96 h exposure. The results of the physicochemical parameters of the Chili River were compared with the Peruvian National Standards for Environmental Quality (ECA for water (categories 3 and 4 and recorded high values of biochemical oxygen demand BOD5, NH4 and PO4, and low dissolved oxigen OD values for Tiabaya. In Tingo, NH4 and phosphate were high. In Tiabaya, water was considered more toxic than at Tingo.

  10. Different molecular conformations co-exist in each of three 2-aryl-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamides: hydrogen bonding in zero, one and two dimensions.

    Narayana, Badiadka; Yathirajan, Hemmige S; Rathore, Ravindranath S; Glidewell, Christopher


    4-Antipyrine [4-amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one] and its derivatives exhibit a range of biological activities, including analgesic, antibacterial and anti-inflammatory, and new examples are always of potential interest and value. 2-(4-Chlorophenyl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide, C19H18ClN3O2, (I), crystallizes with Z' = 2 in the space group P\\overline{1}, whereas its positional isomer 2-(2-chlorophenyl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide, (II), crystallizes with Z' = 1 in the space group C2/c; the molecules of (II) are disordered over two sets of atomic sites having occupancies of 0.6020 (18) and 0.3980 (18). The two independent molecules of (I) adopt different molecular conformations, as do the two disorder components in (II), where the 2-chlorophenyl substituents adopt different orientations. The molecules of (I) are linked by a combination of N-H...O and C-H...O hydrogen bonds to form centrosymmetric four-molecule aggregates, while those of (II) are linked by the same types of hydrogen bonds forming sheets. The related compound N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(3-methoxyphenyl)acetamide, C20H21N3O3, (III), is isomorphous with (I) but not strictly isostructural; again the two independent molecules adopt different molecular conformations, and the molecules are linked by N-H...O and C-H...O hydrogen bonds to form ribbons. Comparisons are made with some related structures, indicating that a hydrogen-bonded R2(2)(10) ring is the common structural motif. PMID:27585929

  11. Photometric redshifts and clustering of emission line galaxies selected jointly by DES and eBOSS

    Jouvel, S.; et al.


    We present the results of the first test plates of the extended Baryon Oscillation Spectroscopic Survey. This paper focuses on the emission line galaxies (ELG) population targetted from the Dark Energy Survey (DES) photometry. We analyse the success rate, efficiency, redshift distribution, and clustering properties of the targets. From the 9000 spectroscopic redshifts targetted, 4600 have been selected from the DES photometry. The total success rate for redshifts between 0.6 and 1.2 is 71\\% and 68\\% respectively for a bright and faint, on average more distant, samples including redshifts measured from a single strong emission line. We find a mean redshift of 0.8 and 0.87, with 15 and 13\\% of unknown redshifts respectively for the bright and faint samples. In the redshift range 0.6h < -21.0. We note that biasing is derived from the galaxy clustering relative to a model for the mass fluctuations. We investigate the quality of the DES photometric redshifts and find that the outlier fraction can be reduced using a comparison between template fitting and neural network, or using a random forest algorithm.

  12. 卡培他滨联合奥沙利铂治疗进展期胃癌的临床观察%Xeloda Combined with Oxaliplatin Regiment in the Treatment of Patients with Advanced Gastric Carcinoma

    闫红艳; 李莉


    目的 研究卡培他滨联合奥沙利铂治疗进展期胃癌的疗效及不良反应.方法 给予进展期胃癌患者XELOX方案化疗,Xeloda 1000mg/(m2次),每日2次,d1~d14;OXA 130mg/m2,d1,静滴3~4h.21d为一个周期,2周期化疗结束后评价疗效.结果 25例中CR 1例,PR 12例,SD 6例,PD 6例,RR为52%,中位TTP 6.2个月,中位MST 12.5个月,临床获益率76%.主要毒性反应为末梢神经毒性,其次为骨髓抑制、消化道反应、手足综合征,治疗中没有发生治疗相关性死亡,患者耐受性较好.结论 卡培他滨联合奥沙利铂方案治疗晚期胃癌疗效肯定,毒性反应轻,并可以明显改善患者生存质量,延长患者生存期,值得临床进一步推广.

  13. Charged particle periodicity in the Saturnian magnetosphere

    The low energy charged particles (LECP) experiments on the Voyager 1 and 2 spacecraft performed measurements of electrons (approx.22 keV to approx.20 MeV) and ions (approx.28 keV to approx.150 MeV) during the Saturn encounters in 1980 and 1981. Count rate ratios of two of the low energy electron (22 to 35 keV and 183 to 500 keV) and ion (43 to 80 keV and 137 to 215 keV) channels exhibit an approximation 10 hour periodicity in the outer Saturnian magnetosphere beyond the orbit of Titan. Electron ratios vary from approx.50 to approx.300; ion ratios vary from approx.3 to approx.20. Similar but less pronounced periodicities are observed for higher and lower energy electron and ion spectral indices. Three complete cycles were observed during the Voyager 2 outbound portion of the encounter from which were determined an electron ratio period of 10/sup h/21/sup m/ +- 48/sup m/ and an ion ratio period of 9/sup h/49/sup m/ +- 59/sup m/. Using Saturn Kilometric Radiation (SKR) and Saturn Electrostatic Discharge (SED) periods, extrapolation backward from Voyager 2 to Voyager 1 suggests that the periodicities are Saturnian rather than Jovian in nature, and that they persist in phase for time intervals at least as long as 287 days. Ratio minima, or spectral hardenings, occur in the same hemisphere as do auroral brightenings, SKR activity, and spoke enhanement. We interpret the observations as prima facie evidence of an asymmetry in the Saturian magnetic field and the root cause of the observed SKR periodicity

  14. Hopane, sterane and n-alkane distributions in shallow sediments hosting high arsenic groundwaters in Cambodia

    The presence of elevated As in ground waters exploited for drinking water and irrigation in South-East Asia is causing serious impacts on human health. A key mechanism that causes the mobilization of As in these waters is microbially mediated reductive transformation of As-bearing Fe(III) hydrated oxides and the role of degradable organic matter (OM) in this process is widely recognized. A number of different types of OM that drive As release in these aquifers have been suggested, including petroleum derived hydrocarbons naturally seeping into shallow sediments from deeper thermally mature source rocks. However, the amount of information on the characteristics of the OM in South-East Asian aquifers is limited. Here the organic geochemical analyses of the saturated hydrocarbon fractions and radiocarbon analysis, of two additional sites in SE Asia are reported. The results show that the OM in a given sedimentary horizon likely derives from multiple sources including naturally occurring petroleum. The importance of naturally occurring petroleum as one of the sources was clearly indicated by the n-alkane CPI of approximately 1, the presence of an unresolved complex mixture, and hopane (dominated by 17α(H),21β(H) hopanes) and sterane distribution patterns. The results also indicate that the OM in these aquifers varies tremendously in content, character and potential bioavailability. Furthermore, the presence of petroleum derived OM in sediments at both sites doubles the number of locations where their presence has been observed in association with As-rich, shallow aquifers, suggesting that the role of petroleum derived OM in microbially mediated As release might occur over a wider range of geographical locations than previously thought

  15. A comparative haematological analysis of Asian Elephants Elephas maximus Linnaeus, 1758 (Mammalia: Proboscidea: Elephantidae managed under different captive conditions in Sri Lanka

    R.K.D. Mel


    Full Text Available Haematological parameters were assessed from elephants of three institutions in Sri Lanka with different captive conditions, in order to evaluate if different captive conditions influence the physiology of the animals. The institutions were: The National Zoological Gardens (NZG, where elephants live a comparatively sedentary lifestyle, Pinnawala Elephant Orphanage (PEO, where elephants are allowed to walk and engage in intra-specific behaviours, and Millennium Elephant Foundation (MEF, where the elephants are used for tourist rides. Four adult females were examined from the NZG, while only two males and two females could be examined from PEO and MEF respectively. All animals were sampled on four consecutive days. Blood glucose levels, total white blood cells (WBC, red blood cells (RBC, packed cell volume (PCV, mean corpuscular volume (MCV and differential white blood cell counts were carried out. Certain blood parameters of the elephants from NZG differed significantly from the parameters of the elephants from PEO and MEF. These were, the total WBC counts (Kruskal-Wallis, H=21.92, 2d.f., P=0.000, the lymphocyte count (Kruskal-Wallis, H=16.40, 2d.f., P=0.00 and the Neutrophil: Lymphocyte ratios (Kruskal-Wallis , H=14.58, 2d.f., P less than 0.05. PCV , blood glucose levels and monocyte counts were also shown to be significantly different among the three groups (Kruskal-Wallis P less than 0.000. We suggest that differences in the stress levels associated with the different management methods might influence these haematological values.

  16. Exchange coupling transformations in Cu (II) heterospin complexes of “breathing crystals” under structural phase transitions

    Family of “breathing crystals” is the polymer-chain complexes of Cu(hfac)2 with nitroxides. The polymer chains consist of one-, two- or three-spin clusters. The “breathing crystals” experience simultaneous magnetic and Jahn-Teller type structural phase transitions with change of total cluster spin and drastic change of bond lengths (ca. 10-12%). For the first time the intra-cluster magnetic couplings in ”breathing crystals” have been calculated both by band structure methods GGA + U and hybrid DFT (B3LYP and PBE0) for the isolated exchange clusters. The temperature dependence of the magnetic coupling constant was calculated for two polymer-chain compounds of the “breathing crystal” family - C21H19CuF12N4O6 with the chains containing two-spin clusters and C22H21CuF12N4O6 with the chains of alternating three-spin clusters and one-spin sites. It was found that adding a Hubbard-like parameter not only to the copper 3d electrons but also to the oxygen 2p electrons (GGA + Ud + Up approach) results in an improved description of exchange coupling in the “breathing crystal” compounds. At the same time treatment of the isolated clusters by a large basis hybrid DFT with high computational cost provides a similar quality fit of the experimental magneto-chemical data as that for the GGA + Ud + Up band structure calculation scheme. Our calculations also showed that in spite of the abrupt transformation of the magnetic coupling constant under the phase transition, the band gap in the “breathing crystals” remains about the same value with temperature decrease

  17. Fingerprinting analysis of oil samples for inter-laboratory Round Robin, 2007

    The oil from an oil spill must undergo a complete chemical characterization in order to determine the source of the oil, to distinguish the spilled oil from background hydrocarbons and to evaluate the extent of impact. A study was conducted to determine the ability of international analytical laboratories to independently conduct forensic oil analysis and identification. A Round Robin study was conducted in which advanced chemical fingerprinting and data interpretation techniques were used to differentiate the types and sources of spilled oils. The participants of the Round Robin exercise were the Institute of Inland Water Management and Waste Water Treatment (RIZA) in the Netherlands and the Federal Maritime and Hydrographic Agency (BSH) in Germany. In May 2007, 6 oil samples were distributed to the participants. In the artificial oil spill scenario, 2 oil samples were considered as candidate sources and the other 4 samples were labeled as spilled oils. No other information about these oils was provided before submission of final results. Chemical fingerprinting was carried out using gas chromatography, flame ionization detection and mass spectrometry along with statistical data to determine the source of the spill. N-alkanes, alkylated polyaromatic hydrocarbons, biomarker terpanes and steranes and triaromatic steranes were normalized to C30 17α(H)21β(H)-hopane and then semi-quantitated. Thirty diagnostic ratios of target compounds were calculated from their peak heights and areas at selected ions. Results of the 2 source samples were compared with 4 spill samples. Tiered fingerprinting analysis revealed that source oil 1 was a non-match with spill samples 3 and 4, but a probable match with spill samples 5 and 6. Source sample 2 did not match any of the 4 spilled oils. A lack of background information essential to oil spill identification made it impossible to draw an unambiguous conclusion. 14 refs., 4 tabs., 6 figs

  18. Isolation and characteristics of Shiga toxin 2f-producing Escherichia coli among pigeons in Kyushu, Japan.

    Koichi Murakami

    Full Text Available An increasing number of Shiga toxin 2f-producing Escherichia coli (STEC2f infections in humans are being reported in Europe, and pigeons have been suggested as a reservoir for the pathogen. In Japan, there is very little information regarding carriage of STEC2f by pigeons, prompting the need for further investigation. We collected 549 samples of pigeon droppings from 14 locations in Kyushu, Japan, to isolate STEC2f and to investigate characteristics of the isolates. Shiga toxin stx 2f gene fragments were detected by PCR in 16 (2.9% of the 549 dropping samples across four of the 14 locations. We obtained 23 STEC2f-isolates from seven of the original samples and from three pigeon dropping samples collected in an additional sampling experiment (from a total of seven locations across both sampling periods. Genotypic and phenotypic characteristics were then examined for selected isolates from each of 10 samples with pulsed-field gel electrophoresis profiles. Eight of the stx 2f gene fragments sequenced in this study were homologous to others that were identified in Europe. Some isolates also contained virulence-related genes, including lpfA O26, irp 2, and fyuA, and all of the 10 selected isolates maintained the eae, astA, and cdt genes. Moreover, five of the 10 selected isolates contained sfpA, a gene that is restricted to Shiga toxin-producing E. coli O165:H2 and sorbitol-fermenting Shiga toxin-producing E. coli O157:NM. We document serotypes O152:HNM, O128:HNM, and O145:H34 as STEC2f, which agrees with previous studies on pigeons and humans. Interestingly, O119:H21 was newly described as STEC2f. O145:H34, with sequence type 722, was described in a German study in humans and was also isolated in the current study. These results revealed that Japanese zoonotic STEC2f strains harboring several virulence-related factors may be of the same clonal complexes as some European strains. These findings provide useful information for public health

  19. The Paleocene-Eocene "Greenhouse" Arctic Ocean paleoenvironment: Implications from biomarker results from IODP Expedition 302 (ACEX)

    Weller, P.; Stein, R.


    In order to reconstruct the long-term Cenozoic climate history of the central Arctic Ocean and its role in earth's transition from Paleogene greenhouse to the Neogene icehouse conditions, IODP Expedition 302 (Arctic Ocean Coring Experiment ACEX) visited the Lomonosov Ridge in August 2004. Here, we present new data of organic-geochemical compounds determined in ACEX sediment samples to identify organic matter sources and biomarker proxies to decipher processes controlling organic-carbon accumulation and their paleo- environmental significance. Of special interest was the reconstruction of organic carbon composition, preservation and accumulation (i.e. high productivity vs. anoxia vs. terrigenous input) during periods of extreme global warmth and proposed increased freshwater discharge in the early Cenozoic. Specific source-related biomarkers (e.g. n-alkanes, fatty acids, isoprenoids, carotenoids, steranes/sterenes, hopanes/hopenes, hopanoic acids, aromatic terpenoids, benzohopanes, long-chain alkenones, organic sulfur compounds) and Rock-Eval parameters were determined in the ACEX sediment samples, ranging from the late Paleocene to the middle Miocene in age. The records show highly variable TOC-contents and a large variety and variability of compounds derived from marine, terrestrial and bacterial origin. The distribution of hopanoic acid isomers was dominated by compounds with the biological 17 beta (H), 21 beta (H) configuration indicating a low level of maturity, which was in good agreement with the data from Rock-Eval pyrolysis. Based on the biomarker data, the terrestrial organic matter supply was significantly enriched during the late Paleocene and part of the early Eocene, whereas n-alkanes and n-fatty acids in samples from the PETM and Elmo events as well as the middle Eocene indicate increased aquatic contributions. Furthermore samples from the middle Eocene were characterized by the occurrence of long-chain alkenones, high proportions of lycopane and high

  20. Paleogene biomarker records from the central Arctic Ocean (Integrated Ocean Drilling Program Expedition 302): Organic carbon sources, anoxia, and sea surface temperature

    Weller, Petra; Stein, Ruediger


    During Integrated Ocean Drilling Program Expedition 302 (Arctic Coring Expedition (ACEX)) a more than 200 m thick sequence of Paleogene organic carbon (OC)-rich (black shale type) sediments was drilled. Here we present new biomarker data determined in ACEX sediment samples to decipher processes controlling OC accumulation and their paleoenvironmental significance during periods of Paleogene global warmth and proposed increased freshwater discharge in the early Cenozoic. Specific source-related biomarkers including n-alkanes, fatty acids, isoprenoids, carotenoids, hopanes/hopenes, hopanoic acids, aromatic terpenoids, and long-chain alkenones show a high variability of components, derived from marine and terrestrial origin. The distribution of hopanoic acid isomers is dominated by compounds with the biological 17β(H), 21β(H) configuration indicating a low level of maturity. On the basis of the biomarker data the terrestrial OC supply was significantly enriched during the late Paleocene and part of the earliest Eocene, whereas increased aquatic contributions and euxinic conditions of variable intensity were determined for the Paleocene-Eocene thermal maximum and Eocene thermal maximum 2 events as well as the middle Eocene time interval. Furthermore, samples from the middle Eocene are characterized by the occurrence of long-chain alkenones, high proportions of lycopane, and high ratios (>0.6) of (n-C35 + lycopane)/n-C31. The occurrence of C37-alkenenones, which were first determined toward the end of the Azolla freshwater event, indicates that the OC becomes more marine in origin during the middle Eocene. Preliminary U37K'-based sea surface temperature (SST) values display a long-term temperature decrease of about 15°C during the time interval 49-44.5 Ma (25° to 10°C), coinciding with the global benthic δ18O cooling trend after the early Eocene climatic optimum. At about 46 Ma, parallel with onset of ice-rafted debris, SST (interpreted as summer temperatures

  1. 顺铂联合exosomes抗小鼠肝癌效应的实验研究%Experimental studies on anti-mouse hepatocellular carcinoma effects of cisplatin combined with exosomes

    汪少华; 沈宜; 李静; 向自武; 范维珂; 陈黎


    目的:评价顺铂(DDP)与exosomes联用的抗肿瘤效果,研究其可能机制.方法:采用MTT法检测顺铂对小鼠肝癌H22细胞增殖的影响,用H21源exosomes瘤苗免疫小鼠,3 H-TdR释放法检测exosomes诱导产生的CTL活性及顺铂对CTL杀伤的增敏作用,RT-PCR检测顺铂作用后H22细胞中Fas及exosomes免疫后脾淋巴细胞FasL的mRNA表达水平,Western blot检测顺铂对H22细胞Fas的蛋白表达水平的影响.以小鼠肝癌H22细胞接种BALB/c小鼠建立动物模型,观察顺铂联合exosomes治疗对小鼠生存期的影响.结果:顺铂抑制H22细胞生长呈量效关系;exosomes免疫小鼠可诱导产生针对H22细胞的CTL反应,经2.5 mg/L顺铂预处理24 h的H22细胞对CTL杀伤的敏感性增强(P<0.05).顺铂在mRNA和蛋白水平,显著增强H22Fas的表达;exosomes免疫小鼠后,脾淋巴细胞FasL表达增加.顺铂联合exosomes组小鼠生存期较单独治疗组及对照组明显延长(P<0.05).结论:顺铂与exosomes联合治疗有协同抑制肿瘤的作用,产生协同作用的机制与增强CTL活性有关.

  2. A two-wavelength crystallographic study of a new aluminophosphate containing nickel

    This paper describes the structure of a new aluminophosphate containing nickel. A single crystal of NiAl3P4O18C4H21N4 was used to collect data at Cu Kα and Mo Kα wavelengths on rotating-anode (Rigaku AFC-5R) and sealed-tube (Rigaku AFC-6S) diffractometers, respectively. The monoclinic unit cell was (for Cu Kα) a=10.0209(8), b=15.661(1), c=14.0914(8) A, β=101.216(5) , space group P21/n. Determination of the structure showed that a novel arrangement had been formed, in which nickel occupied an octahedral site in the framework. The elemental analysis confirmed the presence of nickel. The Ni atom is coordinated to two framework O atoms and one water molecule. In addition, two template molecules of ethylenediamine are coordinated to the Ni atom, one monodentate and the other bidentate. The framework also contains three Al atoms and four P atoms that are all tetrahedrally bound to oxygen. A free water molecule is contained in the pores and is hydrogen bonded to the framework. The overall structure consists of aluminosphophate layers linked through Ni atoms. The crystal used for data collection was small (0.02x0.05x0.25 mm), but with the Cu Kα data it was possible to refine all non-H atoms anisotropically to a final R (on F) of 0.057, wR=0.081, with 3497 observed reflections having I>3σ(I) and 309 variables. Using the weaker Mo Kα data, the final agreement factors were R=0.050 and wR=0.055, with 1057 observed reflections and 177 parameters. Between Cu Kα and Mo Kα wavelengths, the difference in f' is -3.32 e for nickel versus 0.15 e for aluminium (i.e. a ratio of 24). An f' difference Fourier electron-density map, based on phases calculated excluding the Ni atom, revealed a single peak of six times the r.m.s. value at the six-coordinate site, which is further evidence that nickel, rather than aluminium, is indeed present at this site. (orig.)

  3. Unenhanced helical computed tomography vs intravenous urography in patients with acute flank pain: accuracy and economic impact in a randomized prospective trial

    Pfister, S.A. [Department of Radiology, University Hospital, Petersgraben 4, 4031, Basel (Switzerland); Medical Imaging Lucerne, Theaterstrasse 7, 6003, Lucerne (Switzerland); Deckart, A.; Laschke, S.; Gasser, T.C. [Department of Urology, University Hospital, Petersgraben 4, 4031, Basel (Switzerland); Dellas, S.; Otto, U.; Buitrago, C.; Wiesner, W.; Bongartz, G. [Department of Radiology, University Hospital, Petersgraben 4, 4031, Basel (Switzerland); Roth, J. [Department of Radiologic Physics, University Hospital, Petersgraben 4, 4031, Basel (Switzerland)


    Unenhanced helical computed tomography (UHCT) has evolved into a well-accepted alternative to intravenous urography (IVU) in patients with acute flank pain and suspected ureterolithiasis. The purpose of our randomized prospective study was to analyse the diagnostic accuracy of UHCT vs IVU in the normal clinical setting with special interest on economic impact, applied radiation dose and time savings in patient management. A total of 122 consecutive patients with acute flank pain suggestive of urolithiasis were randomized for UHCT (n=59) or IVU (n=63). Patient management (time, contrast media), costs and radiation dose were analysed. The films were independently interpreted by four radiologists, unaware of previous findings, clinical history and clinical outcome. Alternative diagnoses if present were assessed. Direct costs of UHCT and IVU are nearly identical (310/309 Euro). Indirect costs are much lower for UHCT because it saves examination time and when performed immediately initial abdominal plain film (KUB) and sonography are not necessary. Time delay between access to the emergency room and start of the imaging procedure was 32 h 7 min for UHCT and 36 h 55 min for IVU. The UHCT took an average in-room time of 23 min vs 1 h 21 min for IVU. Mild to moderate adverse reactions for contrast material were seen in 3 (5%) patients. The UHCT was safe, as no contrast material was needed. The mean applied radiation dose was 3.3 mSv for IVU and 6.5 mSv for UHCT. Alternative diagnoses were identified in 4 (7%) UHCT patients and 3 (5%) IVU patients. Sensitivity and specificity of UHCT and IVU was 94.1 and 94.2%, and 85.2 and 90.4%, respectively. In patients with suspected renal colic KUB and US may be the least expensive and most easily accessable modalities; however, if needed and available, UHCT can be considered a better alternative than IVU because it has a higher diagnostic accuracy and a better economic impact since it is more effective, faster, less expensive and less

  4. Clinical observation on 65 cases of acute myocardial infarction treated with thrombolytic therapy at different time after heart attack and nursing care%急性心肌梗死65例发病后不同时间溶栓治疗临床观察及护理

    张玉兰; 张莉梅; 刘云


    Objective: To investigate the effect of thrombolytic therapy in the treatment of patients with acute myocardial infarction at different time after heart attack and nursing care. Methods: 65 patients with acute myocardial infarction were divided into group A ( n = 21, within 2 hours ), group B( re = 21,2 ~ 4 hours ) and group C( n = 23 ,4 ~ 6 hours ) according to the time from heart attack to the beginning of thrombolytic therapy. The patients in the three groups were given intravenous thrombolytic therapy and meticulous nursing care. The clinical effect was observed and compared among the three groups. Results: The patients'conditions were under control through thrombolytic therapy and appropriate nursing care. No complication and re - infarction occurred. The differences in the comparison of coronary recanalization rate after thrombolytic therapy and the numbers of the patients whose Killip ≥Ⅲ were statistically significant among the three groups ( P <0.01 ). Conclusion: The thrombolytic therapy combined with effective nursing measures can quickly make the coronary artery recanalized, reduce infarction size and incidence of complications so as to reduce fatality rate and promote patient s recovery in the treatment of patients with acute myocardial infarction.%目的:探讨急性心肌梗死患者发病后不同时间溶栓治疗的效果及护理.方法:将65例急性心肌梗死患者按发病至溶栓开始时间分为A组(2 h之内)21例、B组(2~4 h)21例、C组(4~6h)23例,均行静脉溶栓治疗,并给予精心护理,观察、比较三组临床效果.结果:所有病例经溶栓治疗并采用相应护理措施后,病情均得到有效控制,无一例出现并发症及再梗死,三组溶栓后冠脉再通率、心功能Killip≥Ⅲ级例数比较差异有统计学意义(P<0.01).结论:对急性心肌梗死患者行溶栓治疗并结合有效护理措施,能迅速使冠状动脉再通,减少心肌梗死范围及并发症的发生,降低病死率,促进患者早日康复.

  5. Structures and Spectroscopy Studies of Two M(II-Phosphonate Coordination Polymers Based on Alkaline Earth Metals (M = Ba, Mg

    Kui-Rong Ma


    Full Text Available The two examples of alkaline-earth M(II-phosphonate coordination polymers, [Ba2(L(H2O9]·3H2O (1 and [Mg1.5(H2O9]·(L-H21.5·6H2O (2 (H4L = H2O3PCH2N(C4H8NCH2PO3H2, N,N′-piperazinebis(methylenephosphonic acid, (L-H2 = O3PH2CHN(C4H8NHCH2PO3 have been hydrothermally synthesized and characterized by elemental analysis, FT-IR, PXRD, TG-DSC, and single-crystal X-ray diffraction. Compound 1 possesses a 2D inorganic-organic alternate arrangement layer structure built from 1D inorganic chains through the piperazine bridge, in which the ligand L−4 shows two types of coordination modes reported rarely at the same time. In 1, both crystallographic distinct Ba(1 and Ba(2 ions adopt 8-coordination two caps and 9-coordination three caps triangular prism geometry structures, respectively. Compound 2 possesses a zero-dimensional mononuclear structure with two crystallographic distinct Mg(II ions. Free metal cations   [MgO6]n2+ and uncoordinated anions (L-H2n2- are joined together by static electric force. Results of photoluminescent measurement indicate three main emission bands centered at 300 nm, 378.5 nm, and 433 nm for 1 and 302 nm, 378 nm, and 434.5 nm for 2 (λex=235 nm, respectively. The high energy emissions could be derived from the intraligand π∗-n transition stations of H4L (310 nm and 382 nm, λex=235 nm, while the low energy emission (>400 nm of 1-2 may be due to the coordination effect with metal(II ions.

  6. Hydrothermal Petroleum in Active Continental Rift: Lake Chapala, Western Mexico, Initial Results.

    Zarate-del Valle, P. F.; Simoneit, B. R.; Ramirez-Sanchez, H. U.


    Lake Chapala in western Mexico is located partially in the Citala Rift, which belongs to the well-known neotectonic Jalisco continental triple junction. The region is characterized by active volcanism (Ceboruco, Volcan de Fuego), tectonic (1995 earthquake, M=8, 40-50 mm to SW) and hydrothermal (San Juan Cosala & Villa Corona spas and La Calera sinter deposit) activities. Hydrothermal petroleum has been described in active continental rift (East African Rift) and marine spreading zones (Guaymas Basin, Gulf of California). In 1868 the Mexican local press reported that manifestations of bitumen were appearing in front of the Columba Cap on the mid south shore of Lake Chapala. This bitumen is linked to the lake bottom and when the water level decreases sufficiently it is possible to access these tar bodies as islands. Because of these manifestations the Mexican oil company (PEMEX) drilled an exploration well (2,348m) at Tizapan El Alto without success. Hydrothermal activity is evident in the tar island zone as three in-shore thermal springs (26.8 m depth, 48.5° C, pH 7.8 and oriented N-S). The preliminary analyses by GC-MS of the tar from these islands indicate hydrothermal petroleum derived from lake sedimentary organic matter, generated at low temperatures (150° -200° C). The tars contain no n-alkanes, no PAH or other aromatics, but a major UCM of branched and cyclic hydrocarbons and mature biomarkers derived from lacustrine biota. The biomarkers consist of mainly 17α (H),21β (H)-hopanes ranging from C27 to C34 (no C28), gammacerane, tricyclic terpanes (C20-C26), carotane and its cracking products, and drimanes (C14-C16). The biomarker composition indicates an organic matter source from bacteria and algae, typical of lacustrine ecosystems. 14C dating of samples from two tar islands yielded ages exceeding 40 kyrs, i.e., old carbon from hydrothermal/tectonic remobilization of bitumen from deeper horizons to the surface. The occurrence of hydrothermal petroleum in

  7. Unenhanced helical computed tomography vs intravenous urography in patients with acute flank pain: accuracy and economic impact in a randomized prospective trial

    Unenhanced helical computed tomography (UHCT) has evolved into a well-accepted alternative to intravenous urography (IVU) in patients with acute flank pain and suspected ureterolithiasis. The purpose of our randomized prospective study was to analyse the diagnostic accuracy of UHCT vs IVU in the normal clinical setting with special interest on economic impact, applied radiation dose and time savings in patient management. A total of 122 consecutive patients with acute flank pain suggestive of urolithiasis were randomized for UHCT (n=59) or IVU (n=63). Patient management (time, contrast media), costs and radiation dose were analysed. The films were independently interpreted by four radiologists, unaware of previous findings, clinical history and clinical outcome. Alternative diagnoses if present were assessed. Direct costs of UHCT and IVU are nearly identical (310/309 Euro). Indirect costs are much lower for UHCT because it saves examination time and when performed immediately initial abdominal plain film (KUB) and sonography are not necessary. Time delay between access to the emergency room and start of the imaging procedure was 32 h 7 min for UHCT and 36 h 55 min for IVU. The UHCT took an average in-room time of 23 min vs 1 h 21 min for IVU. Mild to moderate adverse reactions for contrast material were seen in 3 (5%) patients. The UHCT was safe, as no contrast material was needed. The mean applied radiation dose was 3.3 mSv for IVU and 6.5 mSv for UHCT. Alternative diagnoses were identified in 4 (7%) UHCT patients and 3 (5%) IVU patients. Sensitivity and specificity of UHCT and IVU was 94.1 and 94.2%, and 85.2 and 90.4%, respectively. In patients with suspected renal colic KUB and US may be the least expensive and most easily accessable modalities; however, if needed and available, UHCT can be considered a better alternative than IVU because it has a higher diagnostic accuracy and a better economic impact since it is more effective, faster, less expensive and less

  8. Balanço de energia em vinhedo de 'Niagara Rosada' Energy balance on 'Niagara Rosada' vineyard

    José Ricardo Macedo Pezzopane


    Full Text Available O método do balanço de energia foi utilizado para caracterizar a variação horária do saldo de radiação e dos fluxos de calor latente, sensível e no solo, em vinhedo cultivado com a cultivar NiagaraRosada', conduzida no sistema de espaldeira, em Jundiaí (SP. Além disso, foram determinadas as relações entre o saldo de radiação (SR no vinhedo e a radiação solar global (RG e a partição da energia disponível ao sistema nos fluxos de calor latente (LE, sensível (H e no solo (G. Em um dia característico de período seco, o LE representou 44% do SR e o H, 48%. Em um dia chuvoso, o LE representou 86% do SR e o H, 21%. Em um dia ensolarado, após um período de chuvas, LE e H foram, respectivamente, 68% e 29% do SR. O G foi, em média, 5,7% e 1,3% do SR para as ruas mantidas capinadas e com forro, respectivamente.The energy balance method was used to characterize the hourly variation of the net radiation, latent and sensible fluxes and soil heat flux on a mature vineyard grown at Jundiaí, São Paulo, Brazil. The grapevines, cv. Niagara Rosada, in the vineyard were wrapped to trellis wires, creating compact hedgerows 2 m apart, 1.7 m height and 0.4 wide, with the foliage 1m above the soil surface. Also, the net and incoming radiation relationships and the partioning of the available energy to the system into latent and heat flux, and soil heat flux were determined for the vineyard. During a sunny day (dry period the latent heat flux was 44% of the net radiation and the sensible heat flux, 48%. However during a rainy day, the latent heat flux was 86% of the net radiation and the sensible heat flux, 21%. During a sunny day, after the occurrence of rain, the latent and sensible heat fluxes were, respectively, 68% and 29% of the net radiation. The soil heat flux was 5.7 an 1.3% of the net radiation, for bare soil and mulched rows, respectively.

  9. Bone SPECT and CT fusion imaging in pediatric neuroblastoma

    Objective: To evaluate the diagnostic performance of bone SPECT and CT fusion imaging in bone metastases from pediatric neuroblastoma. Methods: Twenty-four pediatric patients with neuroblastoma were included in this retrospective study. All patients underwent planar imaging and SPECT integrated with CT. Lesion visibility,diagnostic certainty and diagnostic performance were evaluated with Kolmogorov-Smirnov test and χ2 test. Results: Lesion visibility of SPECT alone, SPECT integrated with CT were significantly better than that of planar imaging (both H=69.000, P<0.05). SPECT and CT fusion imaging, SPECT alone both detected five more bone lesions than planar bone imaging (77 vs 72). The diagnostic accuracy of SPECT imaging (62.34%, 48/77) was significantly higher than that of planar imaging (45.45%, 35/77; χ2=4.416, P<0.05). The sensitivity,specificity and accuracy of SPECT and CT fusion imaging for diagnosing malignant bone lesions were significantly higher than those of planar imaging: 82.35% (42/51) vs 53.19% (25/47), 88.46% (23/26) vs 40.00% (10/25), 84.42% (65/77) vs 45.45% (35/77; χ2=12.571, 14.016, 25.667, all P<0.01). The diagnostic specificity and accuracy of SPECT and CT fusion imaging were significantly higher than those of SPECT alone (53.85%, 14/26; 62.34%, 48/77) (χ2=7.589, 9.606, both P<0.01). However, there was no significant difference of sensitivity between the two methods (χ2=2.942, P>0.05). Diagnostic certainty by SPECT and CT fusion imaging was significantly higher than that by SPECT alone (H=28.000, P<0.05) and by planar imaging (H=21.000, P<0.05). Conclusion: SPECT and CT fusion imaging can detect more bone lesions in patients with pediatric neuroblastoma. It is helpful for diagnosing bone metastases from pediatric neuroblastoma. (authors)

  10. Syntheses and Crystal Structures of Two Coordination Polymers Based on a Flexible Ligand N,N'-Diacetic Acid Imidazolium

    柴小川; 赵玲艳; 张汉辉; 陈义平; 弓巧娟


    Two coordination compounds with a flexible ligand N,N?-diacetic acid imidazolium(HDAM),{[Co(trans-DAM)(bipy)(H2O)2](OH)·4H2O}n 1 and {[Cd(trans-DAM)(bipy)(H2O)](NO3)?2H2O}n 2(bipy = 4,4'-bipyridine),were prepared and characterized by single-crystal X-ray diffraction.Compound 1 crystallizes in monoclinic,space group P2/n with a = 7.589(6),b = 11.444(2),c = 12.894(3)(A°),β = 90.99(3)°,V = 1119.8(4)(A°)^3,Z = 4,C8.5H14N2O5.5Co0.5,Mr = 261.68,Dc = 1.552 g/cm^3,F(000) = 546,μ = 0.832 mm^-1,the final R = 0.0657 and wR = 0.1958.Compound 2 crystallizes in the monoclinic C2 space group with a = 17.479(4),b = 11.689(2),c = 11.670(2),β = 117.13(3)°,V = 2121.9(7)3,Z = 4,C17H21N5O10Cd,Mr = 567.79,Dc = 1.777 g/cm^3,F(000) = 1144,μ = 1.096 mm^-1,the final R = 0.0233 and wR = 0.0638.In 1,the Co(II) ions are linked by μ2-trans-DAM-and bipy ligands to build a 2D(4,4) rectangular grid layer,exhibiting a 4-connected sql net.As for 2,μ3-trans-DAM-and bipy bridge Cd(II) ions form a 2D double-layer,consisting of a couple of(4,4) grid layers,which can be viewed as a(3,4)-connected network.In both compounds,the 2D structures are stabilized by hydrogen bonding interactions to give 3D supramolecular frameworks.Additionally,FT-IR spectroscopy,UV-Visible spectroscopy,and the fluorescent properties are discussed.

  11. Lattice potential energies and thermochemical properties of phase change materials (1-CnH2n+1NH3)2MnCl4(s) (n = 10 and 11)

    Graphical abstract: Two novel crystalline compounds (1-CnH2n+1NH3)2MnCl4(s) (n = 10 and 11) were synthesized. Crystal structures of the two complexes were determined by X-ray crystallography. The lattice potential energies were calculated. Molar enthalpies of dissolution of the compounds were measured by a solution calorimeter. According to Pitzer’s electrolyte solution theory, molar enthalpies of dissolution at infinite dilution and Pitzer’s parameters of the compounds were obtained. Finally, using the molar enthalpies of dissolution and other auxiliary thermodynamic data, the enthalpy change of the dissociation of [MnCl4]2− as for [MnCl4]2-(g)→Mn2+(g)+4Cl-(g) was obtained. - Highlights: • Compounds (1-CnH2n+1NH3)2MnCl4(s) (n = 10 and 11) were synthesized. • Lattice potential energies of the compounds were calculated. • Molar enthalpies of dissolution at infinite dilution of the compounds were obtained. • The molar enthalpy of dissociation of [MnCl4]2−(g) were obtained. - Abstract: Two novel crystalline compounds (1-C10H21NH3)2MnCl4(s) and (1-C11H23NH3)2MnCl4(s), which may be used as solid–solid phase change materials, were synthesized. The compositions and mass fraction purities of the samples prepared were determined by chemical and elemental analyses. The crystal structures of the two compounds were characterised by X-ray crystallography. The lattice potential energies of the two compounds were obtained from crystallographic data. Molar enthalpies of dissolution of the compounds at various values of molality were measured in the double-distilled water at T = 298.15 K by means of an isoperibol solution–reaction calorimeter. According to Pitzer’s unsymmetrical mixing electrolyte solution theory, the values of molar enthalpies of dissolution at infinite dilution and Pitzer’s parameters of the compounds were obtained. Finally, using the values of molar enthalpies of dissolution at infinite dilution (ΔsHm∞) and other auxiliary

  12. Extracting nuclear sizes of medium to heavy nuclei from total reaction cross sections

    Horiuchi, W.; Hatakeyama, S.; Ebata, S.; Suzuki, Y.


    Background: Proton and neutron radii are fundamental quantities of atomic nuclei. To study the sizes of short-lived unstable nuclei, there is a need for an alternative to electron scattering. Purpose: The recent paper by Horiuchi et al. [Phys. Rev. C 89, 011601(R) (2014)], 10.1103/PhysRevC.89.011601 proposed a possible way of extracting the matter and neutron-skin thickness of light- to medium-mass nuclei using total reaction cross section, σR. The analysis is extended to medium to heavy nuclei up to lead isotopes with due attention to Coulomb breakup contributions as well as density distributions improved by paring correlation. Methods: We formulate a quantitative calculation of σR based on the Glauber model including the Coulomb breakup. To substantiate the treatment of the Coulomb breakup, we also evaluate the Coulomb breakup cross section due to the electric dipole field in a canonical-basis-time-dependent-Hartree-Fock-Bogoliubov theory in the three-dimensional coordinate space. Results: We analyze σR's of 103 nuclei with Z =20 , 28, 40, 50, 70, and 82 incident on light targets, H,21, 4He, and 12C. Three kinds of Skyrme interactions are tested to generate those wave functions. To discuss possible uncertainty due to the Coulomb breakup, we examine its dependence on the target, the incident energy, and the Skyrme interaction. The proton is a most promising target for extracting the nuclear sizes as the Coulomb excitation can safely be neglected. We find that the so-called reaction radius, aR=√{σR/π } , for the proton target is very well approximated by a linear function of two variables, the matter radius and the skin thickness, in which three constants depend only on the incident energy. We quantify the accuracy of σR measurements needed to extract the nuclear sizes. Conclusions: The proton is the best target because, once the incident energy is set, its aR is very accurately determined by only the matter radius and neutron-skin thickness. If σR's at

  13. Effect of grapefruit juice and food on the pharmacokinetics of pirfenidone in healthy Chinese volunteers: a diet-drug interaction study.

    Hu, Jinqing; Shang, Dewei; Xu, Xinwen; He, Xiuling; Ni, Xiaojia; Zhang, Ming; Wang, Zhanzhang; Qiu, Chang; Deng, Shuhua; Lu, Haoyang; Zhu, Xiuqing; Huang, Wencan; Wen, Yuguan


    1. Ingestion of grapefruit juice and food could be factors affecting the pharmacokinetics of pirfenidone, a promising drug for treatment of idiopathic pulmonary fibrosis. 2. A randomized, open-label, three-period crossover study was carried out in 12 healthy Chinese male volunteers who were randomized to one of the three treatments: pirfenidone tablets (0.4 g) were orally administered to fasted or fed subjects, or with grapefruit juice. The washout period was 7 d. 3. Significantly reduced maximum plasma concentration (Cmax, 5.0 5 ± 1.39 versus 10.9 0 ± 2.94 mg·L(- 1)), modestly affected area-under-the-plasma concentration-time curve (AUC) from time zero to 12 h post dosing (AUC0-12 h, 21.8 9 ± 6.47 versus 26.1 6 ± 7.32 mg·h·L(- 1)) and delayed time to reach Cmax (Tmax) were observed in fed group compared with fasted group. Similar effects on Cmax (5.8 2 ± 1.23 versus 10.9 0 ± 2.94 mg·L(- 1)) and AUC0-12 h (modest but not statistically significant, 24.4 4 ± 7.40 versus 26.1 6 ± 7.32 mg·h·L(- 1)) were observed for grapefruit juice compared to fasted subjects. 4. Co-administration of pirfenidone with grapefruit juice resulted in modestly reduced overall oral absorption and significantly reduced peak concentrations compared to fasting, which was similar to effect of food ingestion. No adverse events were observed in the study, but relatively dramatic reduction of peak concentrations should raise concerns for clinical efficacy and safety. PMID:26407124

  14. Syntheses and Crystal Structures of [Na(H2O)1/2]X and NH2(CH2CH3)2X and Antioxidant Activity of the Former

    LIU Bin; YANG Bo-Lun


    In order to enhance the water-solubility and biological utilization rate of chrysin, sodium 5,7-dihydroxylflavone-8-sulfonate (1, [Na(H2O)1/2]X, X = C15H9O4SO3, 5,7-dihydroxylflavone-8-sulfonate) was synthesized and its structure was identified on the basis of NMR, FT-IR and elemental analysis. The assembly of 5,7-dihydroxylflavone-8-sulfonate with diethylamide cation afforded diethylamide 5,7-dihydroxylflavone-8-sulfonate (2, NH2(CH2CH3)2X) which was characterized by FT-IR and elemental analysis. The crystal structures of 1 and 2 were determined by X-ray single-crystal diffraction analysis. The crystal of 1 is of triclinic system, space group P1, with a = 8.5628(13), b = 12.8916(19), c = 13.562(2) A, α = 82.494(1), β = 78.601(2), γ = 84.033(2)°, C30H20Na2O15S2, Z = 2, Mr = 730.59, V= 1450.3(4) A3, Dc = 1.673 g/cm3, F(000) = 748, μ = 0.295 mm-1, the final R = 0.0641 and wR = 0.1458. The crystal of 2 crystallizes in the triclinic system, space group P1, with a = 7.689(2), b = 11.184(3), c = 11.734(3) A, α = 74.268(3), β = 81.751(4), γ = 87.991(3)°, C19H21NO7S, Z = 2, Mr= 407.43, V= 961.2(4) A3, Dc = 1.408 g/cm3, F(000) = 428, μ= 0.210 mm-1, the final R = 0.0484 and wR = 0.1195. In 1, the three-dimensional structure is organized into organic and inorganic regions; the flavone skeletons are stacked into organic regions by π…π stacking interactions; inorganic regions are generated by Na-O coordination bonds among sulfonate groups, coordinated water molecules and NaI. The sulfonate groups play an important role as a bridge of inorganic and organic regions. One-dimensional chain structure of 2 is extended by N-H…O hydrogen bonds and π…π stacking interactions. Furthermore, the antioxidant activity of 1 was evaluated. The scavenging activity of 1 to DPPH flee radical is better than that of the parent compound chrysin.

  15. Electron spin resonance study of x-irradiated single crystals of ammonium chloroacetate

    The quadrupole interaction was considered to be a second order perturbation. Using perturbation theory, formulas were derived for the positions and relative intensities of both allowed (Δm = 0) and forbidden (Δm = +- 1, +- 2) transitions. Using this information, expected spectral patterns were constructed for comparison with observed spectra. It has also been possible to determine the signs of chlorine hyperfine coupling parameters. In this way the complete chlorine coupling tensors were obtained for both the magnetic and quadrupole interactions in the CClHCOONH4 radical. The chlorine magnetic hyperfine couplings are A/sub x/ = 20.5 G perpendicular to the radical plane, A/sub y/ = -5.2 G perpendicular to the C-Cl bond (in the radical plane) and A/sub z/ = -6.3 G in the direction of the C-Cl bond. The quadrupole couplings are P/sub x/ = 2.3 G perpendicular to the radical plane, P/sub y/ = 2.1 G perpendicular to the C-Cl bond (in the plane) and P/sub z/ = -4.4 G in the direction of the C-Cl bond. The hydrogen hyperfine tensor components are A/sub x//sup H/ = -21.8 G perpendicular to the radical plane, A/sub y//sup H/ = -9.3 G in the direction of the C-H bond and A/sub z//sup H/ = -32.5 G perpendicular to the C-H bond (in the radical plane). The g-factor has the values g/sub x/ = 2.0021 perpendicular to the radical plane, g/sub y/ = 2.0080 perpendicular to the C-Cl bond (in the radical plane) and g/sub z/ = 2.0081 in the C-Cl bond. The direction of the C-Cl bond of the radical was inferred. Evaluation of the hydrogen hyperfine couplings has led to the determination of the direction of the C-H bond. From this information the radical was determined to be a planar π-radical. A determination was made of the spin densities of the unpaired electron in the various orbitals: C2p/sub x/ = +0.76, Cl 3s = +0.0017, Cl 3p/sub x/ = +0.175, and Cl 3p/sub z/ = -0.012

  16. Influence of Relief on Vegetation Factors and Agrotechnical Differentiation Measures in Transylvania Plain

    Ioana Moraru, Paula; Rusu, Teodor; Bogdan, Ileana; Ioan Pop, Adrian


    Transylvanian Plain (TP), with an area of 395.616 hectares, has a special importance for Romanian agriculture being characterized as a region orographically represented by hilly areas hills whereas climatically appears as a plain. Physical-geographical conditions from TP (low level of forestation; climate specific to plains) have resulted in numerous land degradation phenomena: land erosion, landslide, draining of gradient springs and groundwater level. These conditions create a favourable framework for the development of anthropic morphogenetic processes, as well as those triggered by natural mechanisms, thus intensifying the pace and their territorial expansion. Rainfall, through annual distribution and spring-summer pluvial aggressiveness, require the implementation of preservation measures on arable land, particularly for spring cultures. Along with rainfall, more factors are involved: relief, by the high degree of fragmentation and through tilting slopes; vegetation, by the dominance of cultivated plants and by the advanced state of degradation of vegetal grasslands (especially on southern slopes); lithology, by the predominance of loose rocks (sand, marl, sandstone etc.). In order to determine the influence of landscape morphology on the agro-technical characterization of land, 11 HOBO Micro Stations (H21-002) have been implemented from April to October in the locality Caianu, at various altitudes (311-441 m) at exposure coverage (N, NW, W, S, SE, E, NE). HOBO Smart Temp (S-TMB-M002) temperature sensors and Decagon EC-5 (S-SMC-M005) moisture sensors were connected to HOBO Micro Stations. Additionally, in 4 of the 11 sites, tipping bucket rain gauges (RG3-M) were deployed to measure precipitation. Each station stored electronic data regarding ground temperature at 3 depths (10, 20, 30 cm), humidity at a depth of 10 cm, air temperature (1 m) and precipitation. Data were downloaded from the Micro Stations via a laptop computer using HOBOware Pro Software Version

  17. Effects of variations in flow characteristics through W.P. Franklin Lock and Dam on downstream water quality in the Caloosahatchee River Estuary and in McIntyre Creek in the J.N. “Ding” Darling National Wildlife Refuge, southern Florida, 2010–13

    Booth, Amanda C.; Soderqvist, Lars E.; Knight, Travis M.


    Franklin Lock increases. The highest FDOM recorded during a survey was at Billy’s Creek. Chlorophyll fluorescence was positively correlated with flow at Franklin Lock, with 23 percent of the variation explained by the flow rate at Franklin Lock. An increase in flow rate at Franklin Lock resulted in a decrease in pH (21 percent of variation explained by flow rates). Data from the pH surveys indicate an increase in pH with distance from Franklin Lock. Turbidity and dissolved oxygen near the surface in McIntyre Creek were not correlated with flow rate at Franklin Lock. Moving-boat surveys did not document a change in turbidity or dissolved oxygen with a change in distance from the Franklin Lock. Correlations between Franklin Lock flow rate and water quality in McIntyre Creek indicate that releases at Franklin Lock affect water quality in the Caloosahatchee River Estuary and Ding Darling Refuge.

  18. Production of 57Co, 109Cd, 111In and 117mSn using CV-28 Cyclotron at IPEN-CNEN/SP

    This work describes the production of 57Co, 109Cd, 111In and 117mSn, very important radioisotopes applied in several areas, using the CV-28 Cyclotron at IPEN-CNEN/SP. 57Co (t1/2 = 271.3 d) and 109Cd (t1/2 = 462.6 d) were obtained through the reactions natNi(p,xn)57Co and 109Ag(p,n)109Cd. The mean thick target yields for 57Co were 346.69kBq/μA.h (9.37μCi/μA.h), for the direct production and 150.59kBq/μA.h (4.07μCi/μA.h), through the decay of 57Ni (11.31 days after EOB - End of Bombardment). A flood source was filled with 222MBq (6mCi) of 57Co prepared by a chemical separation method with a separation yield of 93%. A composite target of Ni and Ag was prepared and a chemical separation method proposed to allow the separation between the targets and 57Co and 109Cd. The yields of the composite target were: 947.94kBq/μA.h (25.62μCi/μA.h) of 57Co - direct reaction, 259.00kBq/μA.h (7μCi/μA.h) of 57Co - indirect reaction and 71.41kBq/μA.h (1.93μCi/μA.h) of 109Cd. The chemical separation yield was 80% for 57Co and 109Cd. 111In (t1/2 = 67.5 h) was produced by the 112Cd(p,2n)111In reaction. The Cd targets were prepared by electroplating of CdSO4 solution in copper and copper/nickel backings. After being irradiated, a chemical separation was performed by an acetic acid extraction method, with an overall recovery yield for 111In higher than 95%. The level of the chemical impurities Cd, Ni and Cu were bellow than the permissible values. 117mSn (t1/2 = 14 d) was prepared by the nuclear reactions natSn(p,xn)117Sb →117mSn. The production thick target yield of 117mSn was 784.4kBq/μA.h (21.20μCi/μA.h) and with the proper decay time of its precursor, 117Sb, no radionuclidic impurities appeared in the final product. A chemical separation method was developed to separate first 117Sb from the irradiated Tin and then 117mSn from Sb with a good chemical yield. The quality control procedures showed the good quality of the 117mSn. (author)

  19. Dicarbollylamine ligand as a tunable template for sigma,sigma- and pi,sigma-bonding modes: syntheses, structures, and theoretical studies of eta5:eta1-coordinated constrained-geometry group 13 metal complexes.

    Lee, Jong-Dae; Kim, Sung-Kwan; Kim, Tae-Jin; Han, Won-Sik; Lee, Young-Joo; Yoo, Dae-Hwan; Cheong, Minserk; Ko, Jaejung; Kang, Sang Ook


    10] (R = H 21, Me 22), desired pi,sigma-CGCs, [{(eta (5)-RC 2B 9H 9)(CH 2) 2(eta (1)-NBz 2)}GaMe] (R = H 19, Me 20) or [{(eta (5)-RC 2B 9H 9)(CH 2) 2(eta (1)-NHBz)}AlMe] (R = H 23, Me 24), were generated, respectively. DFT calculation on 5 provides evidence of existence of pi,sigma-bonding of dicarbollylamine ligand to the aluminum atom: pi-bonding interaction of a dicarbollyl unit becomes intensified in the presence of a weak sigma-bonding amine-tethered group. Furthermore, preference for the formation of pi,sigma-bonding was predicted by optimizing a reaction profile including sigma,sigma- and pi,sigma-structures as well as transition state structures for each methylene- and ethylene-spaced ligand system, 3-5 and 14- 18, to reveal that pi,sigma-bonding interaction is more favorable in the case of a methylene-tethered ligand system. PMID:18597462

  20. Artesdiaquine and Primaquine combined treatment is more effective for Malaria vivax

    Santoso Santoso


    Full Text Available Abstrak Latar belakang: Pengobatan malaria di Kabupaten OKU sejak tahun 2009 telah menggunakan artesdiakuin untuk malaria vivak dan malaria falsiparum. Penelitian bertujuan untuk mengetahui perbedaan gejala klinis awal penderita malaria vivak dan malaria falsiparum, efektivitas dan efek samping pemberian artesdiakuin. Metode: Penelitian merupakan kuasi eksperimen menggunakan metode pre-post test. Sampling dilakukan secara consecutive terhadap pasien Puskesmas Pengaringan, OKU selama bulan Februari sampai Juni 2010. Diagnosis malaria didasarkan adanya plasmodium pada darah pasien secara mikroskopis. Seluruh pasien yang didiagnosis malaria diterapi artesdiakuin pada H0 sampai H2 sedangkan pemberian primakuin hanya dilakukan pada H0. Pengamatan dilakukan i selama 28 hari yaitu pada H0 sampai H3, H7, H14, H21 dan H28. Pengamatan efek samping dilakukan pada H0 sampai H3 sedangkan penilaian efikasi obat dilakukan setelah H28. Hasil: Diperoleh jumlah penderita malaria falsiparum sebanyak 23 orang dan malaria vivak sebanyak 12 orang. Gejala klinis awal sebelum terapi ditemukan pada 91,3%  pada subjek dengan malaria falciparum berupa menggigil, anoreksia, sakit kepala, pusing dan nyeri otot. Gejala tersebut terjadi pada 50% subjek dengan malari vivak. Obat anti-malaria artesdiakuin memiliki efikasi yang baik (100% terhadap penderita malaria vivax namun pada penderita malaria falsiparum hanya diperoleh 87%. Efek samping artesdiakuin ditemukan berupa gatal, pusing, mual, muntah dan nyeri lambung. Efek samping obat lebih berat pada penderita malaria falsiparum dibandingkan malaria vivak. Kesimpulan: Penderita malaria vivax lebih banyak yang tidak mengalami gejala klinis awal. Artesdiakuin lebih efektif pada penderita malaria vivak dibandingkan penderita malaria falsiparum. Efek samping yang ditemukan berupa menggigil, anoreksia, sakit kepala, pusing dan nyeri otot. (Health Science Indones 2010; 1: 26 -32 Kata kunci: malaria, artesdiakuin, efektivitas, efek

  1. Effects of Dermlin and Mepilex Border combined with oxygen therapy on bedsore%德莫林及美皮康联合氧疗对压疮的治疗效果

    朱连荣; 黄英; 王晓媛; 翟冰; 李谦


    目的 探讨德莫林及美皮康联合氧疗对压疮的疗效。方法 将60例由于各种原因所致压疮的老年血液肿瘤病患者随机分成两组,观察组30例,采用德莫林及美皮康联合氧疗的方法治疗处理;对照组30例,采用定时红外线灯照射及常规外科方法处理。比较两组治疗后压疮的恢复情况。结果 观察组压疮的有效率为100%明显高于对照组60%,差异有统计学意义(x2 =17.78,P<0.01),两组患者Ⅰ期压疮的治愈时间以及换药次数比较,差异有统计学意义[(11.4±1.13)h比(3.9±1.13)h,(21.2±1.39)次比(2.8±0.71)分;t分别为3.403,3.411;P<0.01]。结论 德莫林及美皮康联合氧疗的方法对各种原因引起的压疮有良好的治疗效果。%Objective To evaluate the effects of Dermlin and Mepilex Border combined with oxygen therapy on bedsore. Methods 60 neoplastic hematologic disorder patients suffering from bedsores arising from various causes were randomly divided into observational group (n =30) and control group (n =30). The former group was treated by Dermlin and Mepilex Border combined with oxygen therapy, the latter one was treated by timing irradiation of infrared lamp and routine surgical methods. The recovery conditions of bedsores were observed. Results The effective rate of the observational group was significantly higher than those of the control group [( 100% vs 60% ) ;x2 =17.78 ,P <0. 01]. There were significant differences in healing time and times of dressing change between both groups [( 11.4 ± 1.13 ) h vs ( 3.9 ± 1.13 ) h, (21.2 ± 1.39) vs (2.8 ± 0. 71 ) ;t =3. 403,3.411;P < 0. 01]. Conclusions Dermlin and Mepilex Border combined with oxygen therapy has satisfactory effects on treating bedsores arising from various causes.

  2. Avaliação das alterações biomecânicas da córnea antes e após lasik em pacientes míopes e hipermetrópes utilizando Moriá® Sub-Bowman's Keratomileusis (SBK

    Bruno de Freitas Valbon


    Full Text Available OBJETIVO: Avaliar e comparar as alterações biomecânicas da córnea por meio do Ocular Response Analyzer® (ORA Reichert Ophtalmics Instruments, Buffalo, New York, USA antes e após Lasik com Moriá ® Sub Bowman Keratomileusis (SBK One Use Plus (OUP em pacientes míopes e hipermetrópes. MÉTODOS: Foram estudados 33 olhos, sendo 19 olhos míopes e 14 olhos hipermetrópes submetidos à cirurgia refrativa com técnica Lasik com flap fino (100 µ utilizando Moriá SBK OUP. O ORA foi realizado no pré-operatório e 1 mês após a cirurgia para avaliar a biomecânica da córnea. O CH (Corneal Hysteresis, CRF (Corneal Resistance Factor, IOPg (goldmann gold standard, Goldmann correlated intraocular pressure a IOPcc (corneal compensated intraocular pressure e mais 38 variáveis biomecânicas da córnea derivadas do sinal de resposta foram avaliados. O Teste de Kolmogorov-Smirnov foi utilizado para avaliar a distribuição normal. O teste de Wilcoxon foi utilizado para comparar as variáveis antes e após a cirurgia para cada grupo. As diferenças entre as medidas pré e pós-operatórias dos olhos míopes foram comparadas com as diferenças obtidas nos olhos hipermetrópes, utilizando-se o teste de Mann-Whitney. Foi considerado como estatisticamente significante p < 0,05%. RESULTADOS: Houve diferença significativa antes e após Lasik em olhos míopes e hipermetrópes na variável IOPg(Wilcoxon, p <0,05, porém não houve em IOPcc. Somente em olhos míopes houve diferenças significativas em CH e CRF, antes e após Lasik com Moriá SBK OUP, como também 9 parâmetros derivados do ORA Waveform_Sinal Gráfico (aspect1, h1, dive1, path1, p1area1, W11, H11, and w2 path11; Wilcoxon, p <0,05. Em olhos hipermetrópes houve diferenças antes e após Lasik das seguintes variáveis: aspect2, h2, dive2, mslew2 e H21 (Wilcoxon p<0,05.Diferenças nas variáveis IOPg e p1area, antes e após Lasik foram maiores em olhos míopes do que hipermetrópes (Mann-Whitey, p

  3. A Literature Survey to Identify Potentially Volatile Iodine-Bearing Species Present in Off-Gas Streams

    Bruffey, S. H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Spencer, B. B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Strachan, D. M. [Strata-G, Knoxville, TN (United States); Jubin, R. T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Soelberg, N. R. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Riley, B. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)


    Four radionuclides have been identified as being sufficiently volatile in the reprocessing of nuclear fuel that their gaseous release needs to be controlled to meet regulatory requirements (Jubin et al. 2011, 2012). These radionuclides are 3H, 14C, 85Kr, and 129I. Of these, 129I has the longest half-life and potentially high biological impact. Accordingly, control of the release of 129I is most critical with respect to the regulations for the release of radioactive material in stack emissions. It is estimated that current EPA regulations (EPA 2010) would require any reprocessing plant in the United States to limit 129I release to less than 0.05 Ci/MTIHM for a typical fuel burnup of 55 gigawatt days per metric tonne (GWd/t) (Jubin 2011). The study of inorganic iodide in off-gas systems has been almost exclusively limited to I2 and the focus of organic iodide studies has been CH3I. In this document, we provide the results of an examination of publically available literature that is relevant to the presence and sources of both inorganic and organic iodine-bearing species in reprocessing plants. We especially focus on those that have the potential to be poorly sequestered with traditional capture methodologies. Based on the results of the literature survey and some limited thermodynamic modeling, the inorganic iodine species hypoiodous acid (HOI) and iodine monochloride (ICl) were identified as potentially low-sorbing iodine species that could present in off-gas systems. Organic species of interest included both short chain alkyl iodides such as methyl iodide (CH3I) and longer alkyl iodides up to iodododecane (C10H21I). It was found that fuel dissolution may provide conditions conducive to HOI formation and has been shown to result in volatile long-chain alkyl iodides, though these may not volatilize until later in the reprocessing sequence. Solvent extraction processes were found to be significant sources of various organic iodine-bearing species; formation of these

  4. The promoting effect of hyperbaric oxygen on the proliferation of endogenous neural stem cells in neonatal rats with hypoxic ischemic brain damage%高压氧治疗对缺氧缺血性脑损伤新生大鼠内源性神经干细胞增殖的影响

    王晓莉; 赵岩松; 杨于嘉; 谢岷


    目的 探讨高压氧(HBO)治疗缺氧缺血性脑损伤新生大鼠后,内源性神经干细胞增殖的动态变化.方法 将7日龄Sprague-Dawley新生大鼠随机分为正常对照组(对照组)、缺氧缺血脑损伤组(模型组)与HBO治疗组(HBO组).采用经典的Rice-Vannucci法制作缺氧缺血性脑损伤模型,HBO组在脑损伤后3 h内进行HBO治疗,治疗压力为2个绝对大气压,稳压60 min,每日1次,连续7 d.分别于HBO治疗后第3小时、第21小时、第3天、第7天和第14天,采用5-溴-2-脱氧脲苷(BrdU)/巢蛋白免疫荧光双重标记法动态检测缺血侧侧脑室室管膜下区与海马齿状回内源性神经干细胞增殖的动态变化;采用Western blot法检测缺血侧大脑半球巢蛋白的动态变化.结果 HBO组室管膜下区与海马齿状回BrdU +/巢蛋白标记的神经干阳性细胞数分别于HBO治疗后第3小时及第21小时显著增加,第7天达最高水平,并显著高于模型组和对照组(P ). BrdU/nestin immunofluorescence was used to examine the proliferation of NSCs dynami-cally in the subventricular zone (SVZ) and the dentate gyms (DG) at the 3rd h, 21st h, 3rd d, 7th d and 14th d af-ter HBO therapy. Nestin protein was detected by Western blot analysis at various time points after HIBD. Results In the HIBD rats treated with HBO, proliferation of endogenous NSCs was observed in the SVZ and DG. The prolifer-ating NSCs increased at the 3rd h and 21st h after HBO therapy in the SVZ and DG respectively, peaked at the 7th d after HBO therapy, and decreased by the 14th d after HBO therapy, though their level was still higher than that in the controls. The Western blot analysis showed that nestin protein began to increase at the 21st h after HBO therapy, peaked at the 7th d after HBO therapy, then decreased. Conclusion HBO administered within 3 h after HIBD can promote proliferation of endogenous NSCs in neonatal rats after HIBD.

  5. Fauna de flebotomíneos do município de Bandeirantes, no Estado do Paraná Phlebotomine sandflies of Southern Brazil

    Rubens Massafera


    ,552 (85.7% specimens were captured in intradomiciliary and peridomiciliary environments, 2,332 (91.3% of them in a pigsty. These two species predominated between 20h-21h when 90.4% of the specimens were captured. CONCLUSIONS: Five sandfly species, N. whitmani, N. neivai, Migonemyia migonei, Pintomyia pessoai and Pintomyia fischeri, potential vectors of cutaneous leishmaniasis, were captured. The importance of the two former species is emphasized, since both presented similar behavior in regard to seasonal period, hourly frequency and predominance in the anthropic environment. Besides, N. whitmani was the most predominant species.


    张鲁伟; 周荣祥


    目的 探讨缺乏酸性N端反式激活区的截短型p63(△Np63)和MDM2蛋白在膀胱移行细胞癌(TCC)组织中的表达及其临床意义.方法 用免疫组织化学法,检测35例石蜡包埋TCC组织标本中△Np63和MDM2的表达,以38例正常膀胱黏膜作为对照.结果 膀胱癌组30例(83.3%)△Np63蛋白呈阳性表达,膀胱黏膜组7例(18.4%)呈阳性表达,两组比较差异有显著性(uc=5.75,P<0.01).膀胱癌组15例(42.9%)MDM2蛋白呈阳性表达,膀胱黏膜组3例(7.9%)呈阳性表达,两组差异有显著性(x2=11.99,P<0.01).在不同病理分级、临床分期TCC中,△Np63表达差异有显著性(H=21.09、14.99,P<0.01).随着TCC病理分级、临床分期升高,△Np63表达明显增强,呈显著正相关(r=0.64、0.51,P<0.01).在不同病理分级、临床分期TCC中,MDM2表达差异有显著性(x2=16.63,P<0.01;x2=6.72,P<0.05).30例△Np63蛋白阳性表达TCC组织中MDM2蛋白阳性表达10例(33.3%),两者呈显著相关性(x2=7.78,P<0.05).△Np63阳性表达主要集中在低分化、浸润性TCC中,而MDM2则主要表达在高分化、浅表TCC中.结论 △Np63和MDM2与膀胱肿瘤的发生发展密切相关,可作为膀胱肿瘤早期诊断和判断恶性程度的参考指标.

  7. Characterization of Lunar Crater Ejecta Deposits Using Radar Data from the Mini-RF Instrument on LRO

    Patterson, G. W.; Raney, R. K.; Cahill, J. T.; Bussey, B.


    of up to ~1 m. As observed with visible image data, the increased roughness as-sociated with the ejecta of Byrgius A appears nearly continuous to a radial distance of ~70 km. An m-chi decomposition of Mini-RF S-band data for Byrgius A suggests that the portion of ejecta that extends radially from ~10 to 70 km appears far less continuous than is suggested in both optical data and CPR information (Fig. 1). The implication is that we are observing properties of the ejecta and lunar background terrain in the top meter of the surface. In other words the thickness of the ejecta in this distance range is on the order of meters or less. This result suggests that the thickness of ejecta at radial distances > a crater radius differ significantly from estimates of ejecta thickness derived from models of ejecta emplacement [6,7]. References: [1] Melosh, H. J. (1989), Oxford Univ. Press; [2] Ghent, R. R. et al. (2008), Geology, 36, 343-346; [3] Raney, R. K. et al. (2011), Proc. of the IEEE, 99, 808-823; [4] Raney, R.K. et al. (2012), JGR, 117, E00H21; [5] Robinson, M. S. et al. (2010), Space Sci. Rev., 150, 81-124; [6] McGetchin et al. (1973), EPSL, 20, 226-236; [7] Pike (1974), EPSL, 23, 265-274.

  8. p53凋亡刺激蛋白2对饥饿诱导的大肠癌HCT116 p53-/-细胞自噬和凋亡的影响%The role of ASPP2 in starvation-induced autophagy and apoptosis of HCT116 cell line

    侯庆生; 丁谓; 陈德喜; 张玉林; 郭洪亮


    目的 探讨p53凋亡刺激蛋白2(apoptosis stimulating protein 2 0f p53,ASPP2)对饥饿诱导的大肠癌HCT116 p53-/-(p53缺失)细胞自噬和凋亡的影响.方法 实验分3组:(1)绿色荧光蛋白腺病毒(green fluorescent protein adenovirus,rAd-GFP)感染组(对照组);(2)自噬抑制剂LY294002处理组;(3) ASPP 2腺病毒(ASPP2 adenovirus,rAd-ASPP2)感染组.无血清培养基分别培养0、24、48 h诱导细胞自噬和凋亡.利用calcein/PI吸收试验观察各组细胞凋亡水平.细胞转染红色荧光蛋白自噬质粒Lc3(cerise fluorescent protein autophagy plasmid Lc3,CFP-Lc3),在荧光显微镜下观察各组细胞自噬水平.结果 rAd-GFP感染组饥饿24h细胞的自噬水平升高显著(0 h:1.04±0.24;24 h:12.17 ±0.86,P<0.05),而凋亡水平改变差异无统计学意义(0 h:2.01%±0.06%;24 h:3.23%±0.34%,P>0.05);饥饿时间延长至48 h,自噬水平(0 h:1.04±0.24;48 h:21.09±3.32)和凋亡水平(0h:2.01%±0.06%;48 h:30.20%±3.18%)升高,差异均具有统计学意义(均P<0.05).使用LY294002抑制细胞自噬,饥饿24 h细胞凋亡显著增多(rAd-GFP组:3.23%±0.34%;LY294002组:15.68%±1.24%,P<0.01),而饥饿48 h凋亡显著减少(rAd-GFP组:30.20%±3.18%;LY294002组:25.44%±3.01%,P <0.05).rAd-ASPP2感染组饥饿24 h自噬显著降低(rAd-GFP组:12.17±0.86;ASPP2组:1.45±0.45,P<0.01),而凋亡显著升高(rAd-GFP组:3.23%±0.34%;ASPP2组:10.45% ±0.81%,P<0.05);饥饿48 h自噬(rAd-GFP组:21.09 ±3.32;ASPP2组:29.93±3.48)和凋亡(rAd-GFP组:30.20%±3.18%;ASPP2组:36.72%±2.74%)水平均显著升高(均P<0.05).结论 ASPP2通过对自噬的双向调节促进饥饿诱导的大肠癌HCT116 p53-/-细胞凋亡.%Objective To investigate the role of ASPP2 (apoptosis stimulating protein 2 of p53,ASPP2) in starvation-induced autophagy and apoptosis of colorectal cancer HCT116 p53-/-(p53 gene deletion) cell line.Methods The study included three

  9. Global climate change linkage with episodic methane release even in the western north Pacific in the last glacial period

    relation with foraminifera carbon isotopic signal and methane release from the seafloor, biomarker compositions and their carbon isotope have been analyzed in the light of the past activity of methanotrophic bacteria in the oxic-anoxic interface in the overlying water column and/or surface sediment. Analyzed piston cores (MR01-K03 PC4 and PC5, 41 deg. 07.10' N, 142 deg. 24.20' E) at a water depth 1366-m was retrieved from a single site in the eastern margin of the Japanese main island Honshu in the northwest Pacific during MR01-K03 cruise of R/V Mirai. Here we show that marginal sediments from the Northwest Pacific contain a hopanoid compound, 17α(H),21β(H)-hop-22(29)-ene (diploptene), derived from the activity of methanotrophic bacteria in water column and/or surface sediment during a warming period (Interstadial 3) in the Last Glacial. The carbon isotopic compositions of diploptene range between -41.0 per mille and -27.9 per mille (relative to VPDB). In the horizon indicative of a contribution of methanotrophic bacteria, foraminiferal isotope signals were also found with highly depleted 13C compositions of planktonic foraminifera (∼-1.9 per mille, VPDB) and benthic foraminifera (∼-0.8 per mille, VPDB), suggesting indirect records of enhanced incorporation of 13Cdepleted CO2 formed by methanotrophic process that use 12C-enriched methane as their main source of carbon. From combined isotopic data of diploptene and foraminifera, the most prominent signal of methane release was detected in the sediments deposited around 25.4 cal. kyr BP (ca. 100 years' time span), corresponding to the Interstadial 3. This is the first evidence of methane hydrate instability in the open western North Pacific during the Last Glacial. Considering the glacial- interglacial hydrographic conditions in this region, the instability of methane hydrate may be modulated by intermediate water warming and/or the lowering of sea level. Our results suggest that the Northwest Pacific marginal regions

  10. Regio- and Stereoselective 1,3-Dipolar Cycloaddition of Cyclic Azomethine Imines to Platinum(IV)-Bound Nitriles Giving Δ(2)-1,2,4-Triazoline Species.

    Smirnov, Andrey S; Kritchenkov, Andreii S; Bokach, Nadezhda A; Kuznetsov, Maxim L; Selivanov, Stanislav I; Gurzhiy, Vladislav V; Roodt, Andreas; Kukushkin, Vadim Yu


    The complex trans-[PtCl4(EtCN)2] (14) reacts smoothly at 25 °C with the stable cyclic azomethine imines R(1)CH═N(a)NC(O)CH(NHC(O)C6H4R(3))C(b)H(C6H4R(2))((a-b)) [R(1)/R(2)/R(3) = p-Me/H/H (8); p-Me/p-Me/H (9); p-Me/p-MeO/H (10); p-Me/p-Cl/p-Cl (11); p-MeO/p-Me/H (12); p-MeO/p-Cl/m-Me (13)], and the reaction proceeds as stereoselective 1,3-dipolar cycloaddition to one of the EtCN ligands accomplishing the monocycloadducts trans-[PtCl4(EtCN){N(a)═C(Et)N(b)C(O)CH(NHC(O)C6H4R(3))CH(C6H4R(2))N(c)C(d)HR(1)}])((a-d;b-c)) [R(1)/R(2)/R(3) = p-Me/H/H (15); p-Me/p-Me/H (16); p-Me/p-MeO/H (17); p-Me/p-Cl/p-Cl (18); p-MeO/p-Me/H (19); p-MeO/p-Cl/m-Me (20)]. Inspection of the obtained and literature data indicate that the cycloaddition of the azomethine imines to the C≡N bonds of HCN and of Pt(IV)-bound EtCN has different regioselectivity leading to Δ(2)-1,2,3-triazolines and Δ(2)-1,2,4-triazolines, respectively. Platinum(II) species trans-[PtCl2(EtCN){N(a)═C(Et)N(b)C(O)CH(NHC(O)C6H4R(3))CH(C6H4R(2))N(c)C(d)HR(1)}]((a-d;b-c)) [R(1)/R(2)/R(3) = p-Me/H/H (21); p-Me/p-Me/H (22); p-Me/p-MeO/H (23); p-Me/p-Cl/p-Cl (24); p-MeO/p-Me/H (25); p-MeO/p-Cl/m-Me (26)] were obtained by a one-pot procedure from 14 and 8-13 followed by addition of the phosphorus ylide Ph3P═CHCO2Me. Δ(2)-1,2,4-Triazolines N(a)═C(Et)N(b)C(O)CH(NHC(O)C6H4R(3))CH(C6H4R(2))N(c)C(d)HR(1(a-d;b-c)) [R(1)/R(2)/R(3) = p-Me/H/H (27); p-Me/p-Me/H (28); p-Me/p-MeO/H (29); p-Me/p-Cl/p-Cl (30); p-MeO/p-Me/H (31); p-MeO/p-Cl/m-Me (32)] were liberated from 21-26 by the treatment with bis(diphenylphosphyno)ethane (dppe). Platinum(II) complexes 21-26 were characterized by elemental analyses (C, H, N), high-resolution electrospray ionization mass spectrometry (ESI-MS), and IR and (1)H and (13)C{(1)H} NMR spectroscopies and single crystal X-ray diffraction in the solid state for 25·CH3OH, 26·(CHCl3)0.84. The structure of 26 was also determined by COSY-90 and NOESY NMR methods in solution. Quantitative evaluation

  11. Characterization of seed oils from different varieties of watermelon [Citrullus lanatus (Thunb.] from Pakistan

    Mahmood, Z.


    Full Text Available This paper reports the physicochemical characteristics of the seed oils from different varieties of watermelon (Citrullus lanatus cultivated in Pakistan, namely Sugar Baby, Q-F-12, D-W-H-21 and Red Circle-1885. The oil and crude protein contents from watermelon seeds, within the range of 28.25 to 35.65% and 20.50 to 35.00%, respectively, varied significantly (p -1 of oil, saponification index (190.20-205.57 mg KOH g-1 of oil, unsaponifiable matter (0.54-0.82% and color (1.12-4.30 R + 12.20-33.40 Y. The oils revealed a reasonable oxidative parameter range as depicted by the determinations of specific extinction at 232 and 270 nm (2.90-4.40 and 2.05- 3.09, respectively, p-anisidine value (5.60-7.70 and peroxide value (2.90-5.06 meqO2 kg-1 of oil. Linoleic acid was the major fatty acid found in all the seed oils with contributions of 45.30-51.80% of the total fatty acids (FA. Other fatty acids detected were known to be oleic acid (20.2- 23.5%, palmitic acid (15.1-16.9% and stearic acid (11.5- 14.4%. The contents of α- and δ-tocopherol in the oils accounted for 120.6-195.6 and 9.1-58.3 mg kg-1, respectively. The physicochemical attributes of the watermelon seed oils showed a wider variation among the varieties tested. The results of the present study indicate that the seeds of the tested watermelon varieties from Pakistan are a potential source of high-linoleic oil and thus can be explored for commercial use and value addition.Se presentan las características físico-químicas de aceites de diferentes variedades de semillas de sandías (Citrullus lanatus cultivadas en Pakistán: Sugar Baby, QF-12, DWH-21 y Círculo rojo-1885. El aceite y el contenido de proteína cruda de las semillas de sandía están dentro de los rangos: 28,25-35,65% y 20,50-35,00%, respectivamente y varian significativamente (p -1 de aceite, índice de saponificación (190,20-205,57 mg de KOH g-1 de aceite, insaponificable (0,54-0.82% y color (1.12-4.30 de I + 12.20- 33.40 y

  12. Traumatic hip dislocation in children: clinical characteristics and management%儿童创伤性髋关节脱位的临床特点与治疗

    闫桂森; 杨征; 张骥; 朱振华


    central reductions were obtained within 24 h and without avascular necrosis of femoral head.%目的 探讨儿童创伤性髋关节脱位的临床特点及治疗结果.方法 1990年1月至2006年12月收治的资料完整、随访超过2年的儿童创伤性髋关节脱位患者27例,男19例,女8例;年龄2.5~14.4岁,平均10.2岁.16例为高能量损伤,患者年龄(11.58±2.10)岁;11例为日常活动中受伤,患者年龄(8.30±2.93)岁.25例为后脱位,2例伤后自行复位者脱位方向不明.1例合并双侧股骨干骨折者初诊时漏诊.24例于伤后1~9h复位,其余3例复位时间超过24 h.21例闭合复位,6例切开复位.切开术中发现关节内骨软骨块3例,盂羼损伤嵌顿2例,关节囊嵌顿1例.复位后均采用单髋"人"字石膏制动4~6周.结果 27例中10岁以下者占48%.男女比例为2.4:1,左右侧别无差异.高能世损伤与低能量损伤患者年龄差异有统计学意义(t=3.392,P=0.002).全部病例随访2.4~8.3年,平均3.6年.按照Thompson和Epstein评价标准:优24例,良2例,可1例.末次随访时4例发生股骨头坏死,3例残留股骨头膨大和扁平髋.发生股骨头坏死者均为高能量损伤.延时≥24h复位组与<24h复位组股骨头坏死率的差异有统计学意义(X2=19.406,P=0.001).结论 儿童创伤性髋关节脱位所需创伤能量小,合并损伤少,10岁以前多为低能量损伤.闭合复位成功率高,并发症少.闭合复位不能达到中心复位者,可行切开复位及探查修复.24h内获得中心复位、无股骨头骺缺血坏死者疗效满意.

  13. Global system for hydrological monitoring and forecasting in real time at high resolution

    Ortiz, Enrique; De Michele, Carlo; Todini, Ezio; Cifres, Enrique


    connection) and not need update (all upgrade are deployed on the remote server)and DSS is a classical client-server application. The client side will be an HTML 5-CSS 3 application, it runs in one of the most common browser. The server side consist in: A web server (Apache web server); a map server (Geoserver); a Geographical q3456Relational Database Management Sytem (Postgresql+Postgis); Tools based on GDAL Lybraries. A customized web page will be implemented to publish all hydrometeorological information and forecast runs (free) for all users in the world. In this first presentation of the project are invited to attend all those scientific / technical people, Universities, Research Centers (public or private) who want to collaborate in it, opening a brainstorming to improve the System. References: • Liu Z. and Todini E., (2002). Towards a comprehensive physically based rainfall-runoff model. Hydrology and Earth System Sciences (HESS), 6(5):859-881, 2002. • Thielen, J., Bartholmes, J., Ramos, M.-H., and de Roo, A., (2009): The European Flood Alert System - Part 1: Concept and development, Hydrol. Earth Syst. Sci., 13, 125-140, 2009. • Coccia C., Mazzetti C., Ortiz E., Todini E., (2010) - A different soil conceptualization for the TOPKAPI model application within the DMIP 2. American Geophysical Union. Fall Meeting, San Francisco H21H-07, 2010. • Pappenberger, F., Cloke, H. L., Balsamo, G., Ngo-Duc, T., and Oki,T., (2010) Global runoff routing with the hydrological component of the ECMWF NWP system, Int. J. Climatol., 30, 2155-2174, 2010. • Coccia, G. and Todini, E., (2011). Recent developments in predictive uncertainty assessment based on the Model Conditional Processor approach. Hydrology and Earth System Sciences, 15, 3253-3274, 2011. • Wu, H., Adler, R. F., Hong, Y., Tian, Y., and Policelli, F.,(2012): Evaluation of Global Flood Detection Using Satellite-Based Rainfall and a Hydrologic Model, J. Hydrometeorol., 13, 1268-1284, 2012. • Simth M. et al., (2013

  14. 血管活性肠肽拮抗剂[D-p-Cl-Phe6,Leu17]-VIP对快速心房肌电重构的影响%Effects of [D-p-Cl-Phe6, Leu17]-VIP, a vasoactive intestinal peptide antagonist, on rapid atrial electrical remodeling

    肖宪杰; 杨东辉; 高连君; 尹晓盟; 常栋; 杨延宗


    目的 探讨血管活性肠肽拮抗剂[D-p-Cl-Phe6,Leu17]-VIP对快速心房肌电重构的影响.方法 成年杂种犬(12只)分别经右股静脉和颈内静脉穿刺放置导管于右心耳(RAA)和冠状静脉窦导管于冠状静脉窦(CS),经右股动脉放置6F猪尾导管于主动脉根部,全麻机械通气(使血氧饱和度保持在95%以上),下行双侧颈交感-迷走神经干分离.右心耳400次/min高频刺激5h,同时给予双侧颈交感-迷走神经刺激(20 Hz),导致二度房室阻滞以上或窦性心率下降大于30次/min.静脉应用美托洛尔(首次静脉推注1 mg/kg,随之给予0.5 mg·kg-1 ·h-1静脉泵维持)阻断交感神经活性.完全随机分2组:对照组(n=6),经主动脉根部注射生理盐水;实验组(n=6),经主动脉根部首次推注VIP拮抗剂[D-p-Cl-Phe6,Leu17]-VIP 0.5 μg/kg,随后持续注射0.25μg· kg-1 ·h-1;分别在基础状态和心房高频刺激后每小时测量CS及RAA的有效不应期(ERP)、窦性心率及迷走神经刺激时心率.结果 对照组中,基础状态与5h快速心房起搏后窦性心率及交感-迷走神经干刺激时心率差异无统计学意义(P>0.05);经过5h的高频心房起搏和迷走-交感神经干刺激后心房ERP明显缩短[ERP缩短值分别为1 h(-14.5±10.0)ms,2h(-18.4±9.0)ms,3 h(-21.9±11.2)ms,4 h(-25.4±10.3)ms,5 h(-25.9±13.1)ms,P<0.05].实验组中,基础状态与高频心房起搏和交感-迷走神经干刺激后1~5h,窦性心率差异无统计学意义(P>0.05);基础状态下、给予VIP拮抗剂负荷量后、高频心房起搏和迷走-交感神经干刺激后1~5h,ERP没有明显变化(P>0.05).结论 VIP拮抗剂[D-p-Cl-Phe6,Leu17]-VIP能抑制高频心房起搏和迷走-交感神经干刺激所致的快速心房电重构.%Objective To determine the effect of [D-p-Cl-Phe6,Leu17]-VIP,a vasoactive intestinal peptide antagonist,on rapid atrial electrical remodeling (AER).Methods Twelve adult mongrel dogs were subject to catheterization in

  15. 新生儿低血糖与脑损伤的关系%Correlation between neonatal hypoglycemia and brain injury

    丁明明; 周丛乐; 汤泽中; 王红梅; 侯新琳


    whose glucose level was higher than 1.2 mmol/L [34.5% (10/29) vs 0.0% (0/81),x2 =30.72,P<0.01].Duration of hypoglycemia ≥12 h had specificity (100%) and sensitivity (36 %) for predicting brain injury.When duration of hypoglycemia <12 h,the incidence of brain injury was lower than that of the patients whose duration of hypoglycemia≥12 h [21.4% (21/98) vs 6/6,x2 =27.69,P<0.01].Multivariate Logistic regression showed that fetal distress (OR=4.69,95%CI:1.47-14.97,P=0.009),glucose level≤1.2 mmol/L (OR =5.16,95%CI:1.56-17.03,P=0.007),duration of hypoglycemia≥12 h (OR=8 885 220 297.12,95%CI:0.00-∞,P =0.000) and maternal hyperglycemia (OR =3.34,95%CI:1.01-11.02,P=0.048) were independent risk factors for neonatal brain injury.Conclusions Low blood glucose level and prolonged hypoglycemia might induce injury of neurol system.Fetal distress and maternal hyperglycemia might increase the incidence of brain injury in newborns with hypoglycemia.

  16. First look at a major transition period in the early Universe


    with the Hubble Space Telescope. Although none of them is distant enough to allow the detection of intergalactic He+ with HST, He+-absorption towards one of these objects, HS 1700+6416 was detected by the Hopkins Ultraviolet Telescope during NASA's Astro-2 mission in 1995. The first detection of intergalactic He+ was made in 1994 by a group of European astronomers in the quasar Q0302-002, cf. ESA Press Information Note 17-94 (7 July 1994). [4] An ion is an atom that has lost one or more of its electrons. [5] The ionization potential of hydrogen is 13.6 electron volt (eV), of neutral helium, 24.6 eV, and of singly ionized helium, 54.4 eV. In order to ionize the primordial hydrogen and helium atoms, photons of the indicated energies must be emitted by the first galaxies and stars. The corresponding photon wavelengths, all in the far-ultraviolet spectral region, are 912 A (91.2 nm), 504 A (50.4 nm) and 228 A (22.8 nm), respectively. The (Planck-)temperatures required are of the order of 32,000 K, 58,000 K and 127,000 K, respectively, which shows that the second ionization of helium cannot be done by the radiation from stars - they are not sufficiently hot. Thus He+-ions can only be ionized by the radiation from quasars. More information on ESA is available on the World Wide Web at ESO Press Information is available at ESO Photos may be reproduced, if credit is given to the European Southern Observatory.

  17. Chemistry%化学


    O612 01050129 具有微孔/大孔双孔道体系沸石材料的合成=Synthesis of Silicate Materials with Micro/Macroporous Bimodal Pore Systems[刊, 中]/王亚军(复旦大学),唐颐…∥高等学校化学学报.&2000, 21(7).&1013~1015 国家自然科学基金(29873011)资助 O612 01050130 一种新型磷酸钛大单晶的溶剂热法合成与结构研究=Studies on Solvothermal Synthesis and Structure of a New Titanium Phosphate Large Single Crystal[刊, 中]/郭阳虹(吉林大学),施展…∥高等学校化学学报.&2000, 21(7).&1010~1012 国家自然科学基金(29571011)资助 O613 01050131 一种氟气源的制备及热分解=Preparation and Thermal Decomposition of a Kind of Fluorine Source[刊, 中]/刘文元(西北核技术研究所),李辉…∥应用化学.&2000, 17(3).&300~303 国家"八六三”计划资助课题 O613 01050132 铒在HBTMPTP-正庚烷/水溶液间的传质动力学=Mass Transfer of Er(Ⅲ) between HBTMPTP Dissolved in n-Heptane and HAc-NaAc[刊, 中]/乐善堂(中科院长春应用化学所),马根祥…∥高等学校化学学报.&2000, 21(6).&832~835 在(30±0.5)℃下,用层流恒界面池研究了铒在HBTMPTP-正庚烷-0.2mol/L(H,Na)Ac萃取体系中的传质动力学.测定了该体系的界面张力,考察了水相酸度、萃取剂浓度、氯离子浓度、温度和比界面对萃取速率的影响.图6参16 国家自然科学基金(29771028,29801004)资助 O613 01050133 岩石中硼的提取分离及同位素组成的测定=Extraction and Separation of Boron in Rock Samples and lts lsotopic Determination by Thermal lonization Mass Spectrometry[刊, 中]/王刚(中科院青海盐湖所),王蕴慧…∥岩矿测试.&2000, 19(3).&169~172 介绍了一种用Na2CO3+K2CO3混合熔剂对岩石样品进行分解,用硼特效树脂和阴、阳混合离子交换树脂相结合进行岩石样品中硼的纯化分离的方法.采用该方法从岩石样品中提取、分离出来的硼能满足硼同位素质谱法测定的需要,不产生硼同位素分馏,硼同位素测定精度大多优于0.05%.表3参7 国家自然科学基金(29775028)资助 O614 01050134 有机/无机纳米杂化材料负载钛催化剂及聚合研究:Ⅰ.乙烯聚合=Study of Titanium Catalysts Supported on he Organic/Inorganic Hybrid and Polymerization Thereby:Ⅰ.Polymerization of Ethylene[刊, 中]/朱宁(中科院长春应用化学所),唐涛…∥应用化学.&2000, 17(3).&233~237 以苯乙烯与马来酸酐无规共聚物为有机组分,以正硅酸乙酯为无机组分,利用sol-gel方法制得纳米杂化材料,以此为载体合成了杂化材料载体钛系催化剂.图3表3参13 国家自然科学基金(29774028)资助 O614 01050135 硫酸锌与L-α-缬氨酸固体配合物的合成与表征=Synthesis and Characterization of Zinc Sulfate Complexes with L-α-Valine[刊, 中]/张晓玉(西北大学),杨旭武…∥应用化学.&2000, 17(3).&243~247 用半微量相平衡方法研究了ZnSO4-Val-H2O体系在25℃时的溶度图及饱和溶液折光率曲线.体系中未形成新化合物.合成了配合物Zn(Val)SO4*H2O、Zn(Val)2*H2O,并进行了表征.图2表3参13 国家自然科学基金(29871023)资助 O614 01050136 微乳液法制备超细包裹型铁粉=Preparation of Ultrafine Fe Particles by Microemulsion Method[刊, 中]/张朝平(贵州大学),邓伟…∥应用化学.&2000, 17(3).&248~251 应用W/O型微乳液法制备了纳米量级包裹型超细铁粉.由XRD、SEM、TEM和IR谱测试表明:它属于表面活性剂包裹型超细微粒.图3参9 国家自然科学基金(19872021)资助 O614 01050137 以12-钨(钼)磷杂多酸为掺杂剂的导电聚N,N-二甲基苯胺的合成与导电性=Synthesis and Conductivity of Conducting Poly N,N-Dimethaniline Doped by 12-Tungsto(Molybdo) Phosphoric Acid Used as Doping Agent[刊, 中]/张贞文(湖北大学),柳士忠…∥湖北大学学报(自然科学版).&2000, 22(3).&270~273 以12-钨(钼)磷杂多酸为掺杂剂,合成了聚N,N-二甲基苯胺.并利用ICP、元素分析、循环伏安、红外光谱及室温固体电导率的测定等手段进行了表征.结果表明,掺杂的PDMAn/PM12的室温导电率约为12-13 S/cm.图3参6 国家自然科学基金(29971010)资助 O614 01050138 Co(phen)2TATP3+与DNA在旋转金盘金环电极上的相互作用研究=Electrochemical Studies on the Interactions of the Complex of Co(phen)2TATP3+ with DNA at Rotating Au-Au Electrode[刊, 中]/李红(中山大学),蒋雄…∥高等学校化学学报.&2000, 21(7).&995~998 在pH=7.2的Tris缓冲溶液中,利用旋转环盘电极法研究了金电极上Co(phen)2TATP3+与DNA的相互作用,并根据扩散控制和电化学控制下得到的各种参数,对它们作用的模式进行了讨论.图3表2参13 国家自然科学基金(29871036)资助 O614 01050139 双金属杂原子分子筛CrCoBEA的合成、波谱及催化性能研究=Studies on the Synthesis, Spectroscopy and Catalytic Properties of CrCoBEA Metallosilicate[刊, 中]/王亚军(南开大学),唐祥海…∥高等学校化学学报.&2000, 21(7).&999~1004 采用水热晶化法首次合成出BEA结构含铬、钴双金属杂原子分子筛CrCoBEA,对晶化时间、晶化温度、成胶配比等合成条件进行了优化研究,测试其物相、波谱性质和催化性能.图6表1参15 国家自然科学基金重点项目(29733070)资助 O614 01050140 Ru(bpy)2+3在MCM-48中的组装及其发光性质=The Assembly of Tris(Bipyridine)Ruthenium(Ⅱ) in MCM-48 and Photoluminescent Properties of Assembly Products[刊, 中]/房铭(吉林大学),张萍…∥高等学校化学学报.&2000, 21(7).&1016~1017 国家自然科学基金(29771013,59795006)资助 O621 01050141 2-烯丙基-1,1-偕二金属环已烷的合成研究=Synthesis of 2-Allyl-1,1-Gemdimetallic Cyclohexane[刊, 中]/宋国强(江苏石油化工学院),王钒…∥合成化学.&2000, 8(3).&216~219 在无水乙醚中1-锂代环己烯和烯丙基溴化镁于无水溴化锌作用下发生金属化克兰荪重排反应,生成2-烯丙基-1,1-偕二金属环己烷.通过对温度、溶剂量和投料顺序等重排反应主要影响因素的考察和优化,可使2-烯丙基-1,1-偕二金属环己烷的收率达到65%.图2表3 国家自然科学基金(2947043)资助 O621 01050142 沙丘芦苇特有一小分子化合物及其对叶绿体的逆境保护效应[刊, 中]/浦铜良(兰州大学),程佑发…∥科学通报.&2000, 45(12).&1308~1313 用柱层析手段从沙漠地区沙丘芦苇叶片中分离得到一种为该生态型所特有的小分子物质,其化学特征与已报道的逆境胁迫诱导累积的溶质均不同,具多氨基芳香族强极性特征.其自然丰度与月平均气温和月极端高温值为指标的生境高温程度呈显著相关性.并主要存在于光合细胞器叶绿体中.该物质对离体叶绿体在高温下电子传递链的功能具有保护作用.图5表2参15 国家自然科学基金(39870062)资助 O621 01050143 亚胺氧自由基与酚类的反应=The Reaction of Iminoxy Radical with Phenols[刊, 中]/胡家欣(南京大学),吉民…∥高等学校化学学报.&2000, 21(7).&1045~1047 研究了亚胺氧自由基与酚类的反应,一步合成了取代苯并C023唑、萘并及喹啉并C023唑类衍生物,同时探讨了反应机理.表2参8 国家自然科学基金(29375052)资助 O621 01050144 新型磺酰胺类含氮手性配体的合成、晶体结构及催化苯乙酮的不对称氢转移反应=Studies on the Synthesis of New Sulfonylamide Ligand, Crystal Structure and Asymmetric Hydrogen Transfer Reaction of Acetophenone[刊, 中]/董春娥(中科院成都有机化学所),张俊龙…∥高等学校化学学报.&2000, 21(7).&1070~1072 国家自然科学基金(29973042)资助 O624 01050145 P+7原子团簇及其特殊配位=P+7 Clusters and Their Specical Coordinations[刊, 中]/陈明旦(厦门大学),罗海彬…∥厦门大学学报(自然科学版).&2000, 39(3).&341~346 在激光产生的磷原子团簇正离子的质谱图中,P+7具有最强的谱峰.使用分子图形软件设计出24种P+7的同分异构体,并进行分子力学、PM3半经验量子化学和ADF密度泛函优化.从各异构体成键能量的比较中可得知,最稳定的P+7构型是在最稳定的P6的双键位置增加1个磷原子所生成的结构.图2表2参23 国家自然科学基金资助 O626 01050146 硫醚双酐聚酰胺酸的合成及其热稳定性=The Synthesis and Thermal Stability of Thioether Dianhydride Poly(Amic Acid)[刊, 中]/王江洪(中科院感光化学所),沈玉全∥高等学校化学学报.&2000, 21(6).&879~883 合成了硫醚二酐和4-硝基-4′-[N,N-二(2-氨乙基)氨基]偶氮苯(二胺单体)及对应的硫醚聚酰胺酸,并对其结构进行表征.目前,这些聚合物在高敏感非线性光学材料方面显示着广泛的应用前景.图3参14 国家自然科学基金(69637010)资助 O626 01050147 具有光致变色和发光性能的有机化合物的合成及其性能研究=Synthesis and Characteristics of Compounds Having Both Photochromic and Fluorescent Character[刊, 中]/庞美丽(南开大学),王永梅…∥高等学校化学学报.&2000, 21(6).&903~907 以吲哚啉螺苯并吡喃与香豆素衍生物为原料.用DCC缩合酯化法在温和条件下合成了8种新的具有光致变色和发光性能的化合物.所得化合物同时具有光致变色和发荧光的双重特性.图2参15 国家自然科学基金(29872015)资助 O626 01050148 1,2,4-三唑并[3,2-d][1,5]-苯并氧氮杂C024化合物的合成=Synthesis of 1,2,4-Triazolo[3,2-d][1,5] Benzoxazepine Compounds[刊, 中]/刘现军(复旦大学),刘毅…∥高等学校化学学报.&2000, 21(7).&1052~1055 苯并二氢吡喃-4-酮的芳腙衍生的偶氮基碳正离子与腈发生1,3-偶极环加成反应,加成产物通过[1,2]-迁移扩环重排反应,形成新颖的三环系杂环化合物1,2,4-三唑并[3,2-d][1,5]-苯并氧氮杂C024化合物.图1表3参9 国家自然科学基金(A29872007)资助 O626 01050149 四(4-N-吡啶基)卟啉衍生物的合成及表征=Synthesis and Characterization of Meso-Tetrakis(4-Pyridyl) Porphyrin Derivatives[刊, 中]/刘淑清(吉林大学),孙浩然…∥应用化学.&2000, 17(3).&260~263 利用吡啶氮烷基化合成了一系列具有空间效应的水溶性和油溶性的四(4-N-吡啶基)卟啉衍生物及其对应的金属钴卟啉.表5参8 国家自然科学基金(29733090,29803003)资助 O627 01050150 η6-苯乙烯二羰基(三苯基膦)铬配合物的合成与聚合=Synthsis and Polymerization of η6-Styrenedicarbonyl (Triphenylphos- phine) Chromium Complexes[刊, 中]/田晓慧(华东理工大学),林嘉平…∥功能高分子学报.&2000, 13(4).&419~422 国家教委留学回国人员科研启动基金资助 O627 01050151 Schiff碱单核及双核配合物拟酶催化性能的研究=Studies on the Biomimetic Catalytic Character of New Schiff Base Mono-and Di-Nuclear Complexes[刊, 中]/陈新斌(湖南大学),朱申杰…∥高等学校化学学报.&2000, 21(7).&1048~1051 国家自然科学基金(29472055)资助 O627 01050152 Cp2TiCl2/BuiMgBr/THF体系还原二芳基二硒醚=Reduction of Diphenyldiselides with Cp2TiCl2/BuiMgBr/THF[刊, 中]/许新华(南开大学),黄宪∥高等学校化学学报.&2000, 21(7).&1073~1074 国家自然科学基金(29672008)资助 O629 01050153 环肽合成方法的研究进展=Progress in the Study on Synthetic Method of Cyclopeptide[刊, 中]/唐艳春(北京大学),田桂玲…∥高等学校化学学报.&2000, 21(7).&1056~1063 介绍了纯环肽与杂环肽合成的方法、策略及其优缺点,列举了一些常用缩合试剂,探讨了反应溶液浓度、线型肽前体化合物的结构及构象等因素对环化反应的影响.参64 国家自然科学基金(29772001)资助 O63 01050154 N-异丙基丙烯酰胺/N-乙烯基吡咯烷酮水凝胶的研究=Synthesis and Characterization of Copolymer Hydrogels of Poly(N-Isopropylacrylamide-co-N-Vinyl-2-Pyrrolidone)[刊, 中]/刘郁杨(西北工业大学),范晓东…∥功能高分子学报.&2000, 13(4).&380~384 陕西省自然科学基金资助 O63 01050155 组织工程细胞支架及其细胞亲和性改进研究进展=Cells Scaffold for Tissue Engineering and Improvement of Cells Affinity between the Cells and Cells Scaffold[刊, 中]/杨健(中科院化学所),贝建中…∥功能高分子学报.&2000, 13(4).&455~460 国家"973计划” O63 01050156 新型的乙烯聚合催化剂=Novel Catalysts for Ethylene Polymerization[刊, 中]/罗祥(中山大学),伍青∥功能高分子学报.&2000, 13(4).&481~486 广东省自然科学基金资助 O631 01050157 衣康酸对聚丙烯腈原丝结构和性能的影响=Effect of Itaconic Acid on the Structure and Properties of PAN Precursor[刊, 中]/张旺玺(山东工业大学)∥高分子学报.&2000, (3).&287~291 控制单体配比,采用丙烯腈与衣康酸自由基溶液共聚,以偶氮二异丁腈为引发剂在溶剂二甲基亚砜中合成了聚丙烯腈原丝纺丝溶液,并纺制了碳纤维前驱体聚丙烯腈原丝.通过元素分析、IR、DSC、13C-NMR等手段,讨论了共聚单体衣康酸对共聚反应及聚丙烯腈原丝结构和性能的影响.图3表3参11 国家自然科学基金(59783002)资助 O631 01050158 Cr(Ⅱ)与过氧化莰烷酮酰体系引发的活性自由基聚合反应研究=Study on "Living” Radical Polymerization Initiated by Aged Chronum (Ⅱ) Acetate and Ketopinyl Peroxide[刊, 中]/李增昌(中国科学技术大学),吴承佩…∥高分子学报.&2000, (3).&330~334 合成了过氧化莰烷酮酰(KPO),用它和Cr(Ac)2组成的氧化还原体系经陈化后,引发甲基丙烯酸甲酯,甲基丙烯酸β-羟乙酯和丙烯酸进行了聚合反应.其中甲基丙烯酸甲酯具有活性聚合特征.并有效引发含羟基单体如甲基丙烯酸β羟乙酯和丙烯酸进行聚合.图2表4参10 国家自然科学基金(29774027)资助 O631 01050159 MgCl2负载(dbm)2Ti(OPh)2催化乙烯聚合=Ethylene Polymerization with MgCl2-Supported(dbm)2Ti(OPh)2[刊, 中]/阎卫东(中科院化学所),洪瀚…∥高分子学报.&2000, (3).&358~360 报道了用MgCl2负载的二苯氧基二(二苯甲酰甲烷)钛铬合物(dbm)2Ti(OPh),以甲基铝氧烷为助催化剂,常压催化乙烯聚合的结果.图1表2参8 国家自然科学基金(29734141)重点资助 O631 01050160 单分散聚苯乙烯乳胶有序膜在二氧化硅多孔材料制备中的模板作用=Template Effects of the Ordered Film Formed from Monodispersed Polystyrene Latex[刊, 中]/杨振忠(中科院化学所),齐凯…∥高分子学报.&2000, (3).&364~367 以单分散聚苯乙烯乳胶室温形成的有序膜为模板,采用快速溶胶凝胶方法,制备了聚苯乙烯/二氧化硅杂化物,高温烧蚀除去有机物得到了二氧化硅有序孔材料,并讨论了聚苯乙烯有序膜的模板作用机理.图5参15 国家自然科学基金(29774038)资助 O631 01050161 新型含环氧端基聚芳醚酮的合成及表征=Synthesis and Characterization of a Novel Epoxy-Terminated Poly(Aryl Ether Ketoe)[刊, 中]/宣英男(大连理工大学),蹇锡高…∥高分子学报.&2000, (4).&407~410 国家"九五”攻关项目 O631 01050162 超支化聚(胺-酯)的分子设计及其制备=Synthesis and Characterization of Hyperbranched Poly(Amine-Ester)[刊, 中]/陆玉(中国科学技术大学),林德…∥高分子学报.&2000, (4).&411~414 国家自然科学基金(59673026)资助 O631 01050163 聚苯基单醚喹C023啉薄膜的性能与物理老化=The Relations between Properties and Physical Aging of Polyphenylquinoxaline Film[刊, 中]/刘万军(中科院化学所),沈静姝…∥高分子学报.&2000,(4).&415~419 国家科委基础性研究重大项目 O631 01050164 端基附壁模型聚合物环形链的构象统计理论=Configurational Statistics of Model Polymer Loop Chains Attached to a Surface[刊, 中]/廖琦(四川大学),吴大诚∥高分子学报.&2000,(4).&420~425 国家自然科学基金(29774016)资助 O631 01050165 拉格朗日-欧拉方法模拟高分子复杂流体平面收缩流动=The Lagrangian-Eulerian Method:Solutions for Planar Contraction Flow[刊, 中]/李险峰(中科院化学所),袁学锋…∥高分子学报.&2000,(4).&432~437 国家自然科学基金(29634030)资助 O631 01050166 气体膜分离用过渡金属有机络合物-聚酰亚胺杂化材料的研究=Study on Transitional Metal Organic Complex-Polyimide Hybrid Material for Gas Separation Membranes[刊, 中]/史德青(石油大学),孔瑛…∥高分子学报.&2000,(4).&457~461 科技部国家重点基础研究发展规划项目 O631 01050167 原子转移自由基聚合制备聚(丙二醇-g-苯乙烯)=Synthesis of Poly(Propylene Glycol-g-Styrene) from Atom Transfer Radical Polymerization[刊, 中]/黄昌国(华东理工大学),万小龙…∥高分子学报.&2000,(4).&467~471 国家自然科学基金(29634010)资助 O631 01050168 聚苯胺嵌入氧化石墨复合物的合成及表征=Synthesis and Characterization of Polyaniline Intercalated Graphite Oxide Composite[刊, 中]/刘平桂(北京航空材料研究院),龚克成∥高分子学报.&2000,(4).&492~495 国家自然科学基金(59836230)资助 O631 01050169 乙交酯/丙交酯共聚物的体内外降解行为及生物相容性研究=Study on the Biocompatibility and Degradation Behavior of Poly(l-Lactide-co-Glycolide) in vitro and in vivo[刊, 中]/蔡晴(中科院化学所),贝建中…∥功能高分子学报.&2000, 13(3).&249~254 国家重点基础研究发展规划(973)资助 O631 01050170 动态下HTDB/TDI体系凝胶化的研究=Study on the Gelation of Hydroxy-Teminated Polybutadiene/Diisocyanate Blends under Dynamic Condition[刊, 中]/邱方正(华东理工大学),陈建定∥功能高分子学报.&2000, 13(3).&289~292 国家教育部博士点基金资助 O631 01050171 含偶氮苯生色团的聚醚的合成与热致液晶性质=Synthesis and Thermotropic Liquid Crystalline Properties of Two Polyethers Containing Azobenzene Groups[刊, 中]/梁旭霞(中山大学),张灵志…∥功能高分子学报.&2000, 13(3).&277~284 广东省自然科学基金资助 O631 01050172 CoSalphen在壳聚糖上的固定化及对DOPA的催化氧化研究=CoSalphen Immobilized onto Chitosan and Its Activate in Catalytic Oxidation of DOPA[刊, 中]/马会宣(陕西师范大学),胡道道…∥功能高分子学报.&2000, 13(3).&301~305 陕西省自然科学基金资助 O631 01050173 环氧基活化凝胶的开环反应=Ring-Opening Reaction on Epoxy-Activated Resin[刊, 中]/查娟(生物反应器工程国家重点实验室),刘坐镇…∥功能高分子学报.&2000, 13(3).&321~324 由自制的乙酸乙烯酯-甲基丙烯酸缩水甘油酯-甲基丙烯酸烯丙酯大孔共聚物与氨水反应,实现了环氧基的开环反应.考查了不同的氨水浓度、反应温度和时间对胺化转化率的影响,并测定了形成的伯胺基的pKa值为6.9.图4表1参12 国家自然科学基金(29706002)资助 O631 01050174 纳米自组装聚电解质超薄多层膜=Polyelectrolyte Ultrathin Multilayer Films by Nano-Self-Assembly Process[刊, 中]/孙启龙(华南理工大学),王朝阳∥功能高分子学报.&2000, 13(3).&332~336 国家杰出青年科学基金(29725411)与国家自然科学基金(29804003)资助 O631 01050175 十二烷基硫酸钠减慢二苯胺-4-重氮盐及重氮树脂在水溶液中热分解反应的机理=The Mechanism of Thermal Decomposition of DDS and DR in Aqueous Solution Delayed by SDS[刊, 中]/杨伯C025(北京大学),曹维孝∥高等学校化学学报.&2000, 21(6).&969~975 国家自然科学基金(59633110及29774001)资助 O631 01050176 芘标记磺酸基聚电解质在水与DMSO中的荧光光谱=Fluorescence Spectra of Pyrene Labeled Polyelectrolytes with Sulfonate Groups in Water and DMSO[刊, 中]/高峰(华南理工大学),严宇…∥高等学校化学学报.&2000, 21(6).&976~979 国家自然科学基金(29804003)与国家杰出青年科学基金(29725411)资助 O631 01050177 尼龙1012的Brill转变=Brill Transition of Nylon 1012[刊, 中]/李勇进(上海交通大学),颜德岳…∥高等学校化学学报.&2000, 21(6).&983~984 国家自然科学基金(29974017)资助 O631 01050178 热致液晶含氯侧基聚芳醚酮的单晶状条带织构=The Single Crystal-Like Banded Textures in the Films of a Thermotropic Liquid Crystalline Poly(Aryl Ether Ketone) Containing a Lateral Chloro Group[刊, 中]/富露祥(中科院长春应用化学所),张善举…∥高等学校化学学报.&2000, 21(6).&988~990 国家自然科学基金(29974032)资助 O631 01050179 具有RAFT链转移过程的活性自由基聚合的Monte Carlo模拟=Monte Carlo Simulation on Living Radical Polymerization with RAFT Process[刊, 中]/李莉(复旦大学),何军坡…∥高等学校化学学报.&2000, 21(7).&1146~1148 国家自然科学基金资助 O631 01050180 C60-苯乙烯-顺丁烯二酸酐的三元自由基共聚=Free Radical Ternary Copolymerization of C60 with Styrene and Maleic Anhydride[刊, 中]/官文超(华中理工大学),雷洪…∥高等学校化学学报.&2000, 21(7).&1149~1150 国家自然科学基金(29674010)资助 O631 01050181 聚(苯乙烯-b-2-甲基-2-C023唑啉)嵌段共聚物的合成=Studies on Synthesis of P(S-b-Me-OXZ) Block Copolymers[刊, 中]/刘燕飞(华东理工大学),万小龙…∥高等学校化学学报.&2000, 21(7).&1157~1159 国家自然科学重点基金(29634010-2)资助 O631 01050182 乙丙共聚物接枝马来酸酐反应机理的模拟研究=Investigation of Reaction Mechanism of Maleic Anhydride Grafted onto Ethylene-Propylene Copolymer[刊, 中]/黄宏亮(中科院长春应用化学所),姚占海…∥应用化学.&2000, 17(3).&256~259 国家自然科学基金(59873022)资助 O631 01050183 稀土催化丁二烯-异戊二烯共聚合过程中的原位环化反应=In situ Cyclization in the Course of Butadiene Isoprene Copolymerization with Nd-Based Catalyst[刊, 中]/董为民(中科院长春应用化学所),逄束芬…∥应用化学.&2000, 17(3).&272~275 国家自然科学基金(29574179)资助 O631 01050184 计算机模式识别在颜料表面改性中的应用=Study on the Application of Pattern Recognition with a Computer in Surface Modification of Pigment[刊, 中]/严乐美(天津大学),杨桂琴…∥天津大学学报.&2000, 33(3).&344~347 国家自然科学基金(29376254)资助 O631 01050185 共混物中聚氯乙烯凝胶化度测试=Studies on Gelling Value of Polyvingyl Chloride in the Blend[刊, 中]/何本桥(湖北大学),张玉红…∥湖北大学学报(自然科学版).&2000, 22(4).&367~370 湖北省自然科学基金资助 O631 01050186 二氧化硅模板技术制备三维有序聚苯乙烯孔材料[刊, 中]/容建华(中科院化学所),杨振忠…∥科学通报.&2000, 45(15).&1627~1630 以单分散二氧化硅颗粒形成的有序结构为模板,制备了聚苯乙烯孔材料.通过扫描电子显微镜观察了模板、复合物及有序多孔聚苯乙烯的形态.结果表明,所合成的多孔材料中,孔大小均匀,空间排布高度有序,且结构与模板中二氧化硅小球自组装方式完全相同.图6参8 国家自然科学基金(20023003)资助 O631 01050187 光导性偶氮聚合物材料的设计[刊, 中]/周雪琴(浙江大学),陈红征…∥自然科学进展.&2000, 10(6).&543~548 以电荷转移理论为指导,对偶氮聚合物材料结构进行设计,获得了两类光导性偶氮聚合物材料,并对其结构和光导性进行了分析与讨论.图4表1参16 国家自然科学基金(59333071,69890230)资助 O631 01050188 聚合物复合材料中填料的摩擦学作用=Tribological Actions of Filiers in Polymer Composites[刊, 中]/薛群基(中科院兰州化学物理所),阎逢元∥中国科学基金.&2000, 14(4).&211~215 综述了就填料对聚合物复合材料的结构和摩擦学行为的影响,并对目前研究过程中所存在的问题进行了简要分析.图3参29 国家自然科学基金资助 O633 01050189 双马来酰亚胺树脂链结构对熔点和反应活性的影响=The Effect of Chain Structure of Bismaleimide Resins on Melting Point and Reactivity of Reaction[刊, 中]/刘润山(湖北省化学研究所),赵三平…∥功能高分子学报.&2000, 13(4).&487~493 湖北省自然科学基金资助 O636 01050190 高分子固体电解质材料研究进展=Advances in Material of Solid Polymer Electrolytes[刊, 中]/赵地顺(河北科技大学),孙凤霞…∥功能高分子学报.&2000, 13(4).&469~475 河北省自然科学基金资助 O64 01050191 Ru(bpy)2(NCS)2染料敏化CdS/Zn2+-TiO2复合半导体纳米多孔膜的光电化学=Photoelectrochemistry of CdS/Zn2+-TiO2 Composite Semiconductor Nanoporous Films Sensitized by Ru-(bpy)2(NCS)2 Dye[刊, 中]/张莉(北京大学),王艳芹…∥高等学校化学学报.&2000, 21(7).&1075~1079 国家自然科学基金(29773003)资助 O641 01050192 富勒烯笼结构的平面展示法[刊, 中]/叶大年(中科院地质与地球物理所),艾德生…∥科学通报.&2000, 45(16).&1781~1785 采用船式F5和F6与海燕式F5和F6分别表示富勒烯笼几何结构的两种平面图.这些平面图最大的优点是:(1)不破坏富勒烯笼的空间对称性;(2)可以非常清楚地展示出结构中F5和F6的配位形式.这为富勒烯笼的结构几何研究打下了基础.图3参17 国家自然科学基金(49872019)资助 O641 01050193 布朗扩散系数对胶体分形粒子簇扩散控制聚集动力学影响的Monte Carlo模拟=Monte Carlo Simulation to the Effect of Cluster Brownian Diffusion Coefficient on the Colloidal Fractal Cluster Aggregation Kinetics[刊, 中]/王惠(南开大学),王贵昌…∥高等学校化学学报.&2000, 21(6).&922~925 使用表征粒子簇结构的几何形状因子,通过对扩散控制聚集过程的模拟,从微观或介观层次研究了粒子簇结构对粒子簇增长速率和速率常数的影响规律,并与实验结果进行了对比分析.图4表1参15 国家自然科学基金(29573109)资助 O641 01050194 一些富勒烯C60双加成物稳定性的理论研究=Theoretical Studies on the Stabilities of Some C60 Bis-Adducts[刊, 中]/陈中方(南开大学),王贵昌…∥高等学校化学学报.&2000, 21(7).&1127~1129 国家自然科学基金(29773022)资助 O641 01050195 M(bpy)+32(M=Fe,Ru,Os)电子结构与相关性质=Electronic Structure and Related Chemical Properties of Complexes(M=Fe,Ru,Os)[刊, 中]/郑康成(中山大学),匡代彬…∥物理化学学报.&2000, 16(7).&608~612 报道了对配合物(M=Fe,Ru,Os)的量子化学密度泛函法研究的结果,探讨的电子结构特征及相关性质,特别是中心原子对配合物的配位键长、光谱性质、电荷布居及化学稳定性等的影响规律.图2表6参14 国家自然科学基金资助 O642 01050196 纳米HZSM-5分子筛的热稳定性=Thermostability of Nanosized HZSM-5 Zeolite[刊, 英]/张维萍(中科院大连化物所),包信和∥催化学报.&2000, 21(3).&195~196 科技部攀登计划项目 O642 01050197 微量热法研究硒对大肠杆菌生长代谢的作用=Microcalorimetric Study of the Action of Seleniumcontaining Complexes on Growth Metabolism of Escherichia coli[刊, 中]/李曦(武汉大学),刘义…∥物理化学学报.&2000, 16(6).&568~572 采用微量热法测定了Na2SeO3、吗啉、硒代吗啉和N,N'-亚基双硒代吗啉对大肠杆菌作用的热功率输出曲线,根据热功率输出曲线求算在这些药物作用下,大肠杆菌生长代谢的速率常数,并对它们的作用特征进行了比较.图2表1参7 国家自然科学基金资助 O642 01050198 反相气相色谱法测定溶剂在PBMA中的无限稀释活度系数=Measurement of Infinite Diluted Activity Coefficient of Solvent in PBMA by Inverse Gas Chromatography Method[刊, 中]/冯媛媛(华东理工大学),叶汝强…∥华东理工大学学报.&2000, 26(3).&305~308 用反相气相色谱方法测定了16种溶剂在聚甲基丙烯酸丁酯(PBMA)中343~433K范围内的无限稀释活度系数,并用周浩等的高分子溶液分子热力学模型对实验结果进行了关联,结果令人满意.图8表2参15 国家自然科学基金(29976011)资助 O643 01050199 海泡石对非晶态NiB合金催化剂的改性研究=Studies on the Modification of Sepiolite for Amorphous NiB Alloy Catalyst[刊, 中]/石秋杰(南昌大学),陈昭萍…∥物理化学学报.&2000, 16(6).&501~506 以常压气相苯加氢为探针反应,考察了酸改性前后海泡石的加入对非晶态NiB合金催化剂的加氢及抗硫性能的影响,用TPR、TPD表征了催化剂的表面性质,测定了酸改性前后海泡石的比表面及孔径分布,并与活性进行了关联.图3表3参12 国家自然科学基金资助 O643 01050200 F+NCO反应的机理和动力学=Mechanism and Kinetics of the F+NCO Reaction[刊, 中]/侯华(山东大学),王宝山…∥物理化学学报.&2000, 16(6).&517~521 高等学校博士学科点专项科研基金资助 O643 01050201 激光溅射下原子团簇生长的非平衡力学(Ⅱ)=Non-Equilibrium Kinetics of Clusters Growth under Laser Ablation(Ⅱ)[刊, 中]/曹玉群(厦门大学),黄荣彬…∥物理化学学报.&2000, 16(7).&621~626 国家自然科学基金(29890210,29773040)资助 O643 01050202 双(2,4-二甲基戊二烯基)氯化钆的合成及晶体结构=Synthesis and Structure of Bis(2,4-Dimethylpentadienyl)Gadolinium Chloride[刊, 中]/王建辉(吉林大学),母瀛…∥高等学校化学学报.&2000, 21(6).&829~831 国家自然科学基金(29672013,29754143)资助 O643 01050203 温控相转移催化&&水/有机两相催化新进展=Thermoregulated Phase-Transfer Catalysis&&Recent Advances in Water/Organic Biphasic Catalysis[刊, 中]/金子林(大连理工大学),梅建庭…∥高等学校化学学报.&2000, 21(6).&941~946 综述了"温控相转移催化”的原理,温控膦配体的设计、合成及其在水溶性极小的底物高碳烯烃的水/有机两相氢甲酰化反应中的应用效果.图4表5参35 国家自然科学基金(29792074)资助 O643 01050204 Cr-HMS合成、表征及其在催化氧化反应中的应用=Synthesis, Characterization of Cr-HMS and the Application in Catalytic Oxidation[刊, 中]/乐洪咏(复旦大学),华伟明…∥高等学校化学学报.&2000, 21(7).&1101~1104 合成了一系列不同Cr含量的Cr-HMS介孔分子筛,并对其物化性质进行了表征.结果表明,Cr的引入降低了介孔分子筛骨架结构的规整度和孔径的均一程度.Cr-HMS对苯羟基化和环己烷氧化反应均表现出良好的催化活性.并且随Cr含量的增加,催化活性呈火山型分布.图3表3参14 国家自然科学基金(29873011)资助 O643 01050205 新型甲烷无氧芳构化催化剂MoO3/MCM-49=A Novel Catalyst of MoO3/MCM-49 over Nonoxidative Aromatization of CH4[刊, 中]/许宁(吉林大学),阚秋斌…∥高等学校化学学报.&2000, 21(7).&1113~1114 国家自然科学基金(29973011)资助 O643 01050206 以TiCl4为钛源合成钛硅分子筛=Synthesis of Titanosilicalite Using Titanium Tetrachloride as Titanium Source[刊, 英]/张义华(大连理工大学),王祥生∥催化学报.&2000, 21(3).&197~198 以四丙基溴化铵为模板剂,以四氯化钛为钛源,研究了合成小晶粒钛硅分子筛(TS-1)的合成路线.合成的TS-1样品在丙烯环氧化反应中显示有较高的活性(96%)和选择性(95%),H2O2利用率高于95%.图3表1参8 国家自然科学基金(29792071)资助 O643 01050207 稀土氧化物在Fe1-xO基氨合成催化剂中的作用规律=Regular Effect of Rare Earth Oxide on Fe1-xO Catalyst for Ammonia Synthesis[刊, 中]/季德春(浙江工业大学),李小年∥催化学报.&2000, 21(3).&199~203 考察了稀土氧化物对Fe1-xO基催化剂性能的影响.结果表明,稀土氧化物与Fe1-xO作用生成一种复合氧化物REFeO3,从而促进了催化剂的还原,这种促进作用随稀土离子半径不同呈现规律性变化.图1表6参14 国家自然科学基金(29706011)资助 O643 01050208 光电催化降解磺基水杨酸的研究=Study of Photoelectrocatalytic Degradation of Sulfosalicylic Acid[刊, 中]/刘鸿(中科院大连化学物理所),冷文华∥催化学报, 21(3).&209~212 建立了以TiO2/Ni为工作电极、泡沫镍为对电极、饱和甘汞电极为参比电极的光电催化反应体系,研究了在磺基水杨酸(SSal)的光电催化降解过程中,外加电压和溶液pH值对降解速率的影响.图5表1参18 国家自然科学基金(29877024)资助 O643 01050209 多孔TiO2薄膜的表面微结构对甲基橙光催化脱色的影响=Effect of Surface Microstructure of Porous TiO2 Thin Films on Photocatalytic Decolorization of Methyl Orange[刊, 中]/余家国(武汉工业大学),赵修建∥催化学报.&2000, 21(3).&213~216 湖北省自然科学基金资助 O643 01050210 γ-Mo2N催化剂上的乙炔选择加氢=Selective Hydrogenation of Ethyne on γ-Mo2N[刊, 中]/郝志显(中科院大连化学物理所),魏昭彬∥催化学报.&2000, 21(3).&217~220 对γ-Mo2N催化剂上乙炔加氢反应进行了研究.在150℃的反应温度下,乙炔转化率为95%,乙烯选择性达80%,乙烷选择性为4%,丁烯选择性为10%.反应温度和空速对产物的选择性没有明显的影响.图4参17 国家自然科学基金(29625305)资助 O643 01050211 WO3/ZrO2固体强酸催化剂上异丁烷/丁烯的烷基化反应:Ⅱ.过渡金属的助催化作用=Study on Alkylation of Isobutane with Butene over WO3/ZrO2 Strong Solid Acid:Ⅱ. Promotions Effect of Transition Metal[刊, 中]/孙闻东(中科院长春应用化学所),吴越∥催化学报.&2000, 21(3).&229~233 制备了一系列用过渡金属活化的WO3/ZrO2固体强酸催化剂,并对其晶型结构、表面状态和酸量进行了表征.图7表2参22 国家自然科学基金(29792076)资助 O212 01050212 超细镍基催化剂上CH4-CO2重整反应的性能:Ⅰ.制备方法对催化剂结构和还原性能的影响=CH4 Reforming with CO2 over Superfine Ni-Based Catalysts:Ⅰ. Effects of Preparation Methods on Structure and TPR of Catalysts[刊, 中]/许峥(清华大学),张鎏∥催化学报.&2000, 21(3).&234~238 国家博士点基金资助 O643 01050213 SO2对Co3O4/Al2O3选择性催化氧化NO的影响=Effect of SO2 on Catalytic Oxidation of NO over Co3O4/Al2O3[刊, 中]/赵秀阁(华东理工大学),肖文德∥催化学报.&2000, 21(3).&239~242 采用流动态原位IR,TPD及XPS技术研究了NO及SO2在Co3O4/Al2O3金属氧化物催化剂表面上的吸附及脱附行为,并与该催化剂上模拟烟道气中NO的选择性催化氧化活性相关联,考察了SO2对该反应过程的影响及作用机理.图5参13 国家自然科学基金(29633030)资助 O643 01050214 Lewis酸对杂多酸催化异丁烷/丁烯烷基化反应的作用=Effect of Lewis Acid on Alkylation of Isobutane with Butene[刊, 中]/赵振波(中科院长春应用化学所),吴越∥催化学报.&2000, 21(3).&243~246 考察了SbCl5对杂多酸(HPA)催化异丁烷/丁烯烷基化反应的修饰作用,用Hammett指示剂测定了SbCl5/HPA催化剂的酸强度.结果表明,经SbCl5修饰的HPA的酸强度有所提高,SbCl5的加入量、反应温度及反应时间对烷基化油收率及产物分布均有不同的影响.图5表2参15 国家自然科学基金(29792076)资助 O643 01050215 微波固相法制备的ZnCl2/Y在α-蒎烯环氧化物重排反应中的催化性能=Catalytic Performance of ZnCl2/Y Catalyst Prepared by Solid-State Microwave Irradiation for Rearrangement Reaction of α-Pinene Oxide[刊, 中]/尹笃林(湖南师范大学),银董红∥催化学报.&2000, 21(3).&251~254 国家自然科学基金(29572042,29972011)资助 O643 01050216 Co-Mo/HZSM-5甲烷无氧芳构化催化剂上的积炭=Characterization of Coke on Co-Mo/HZSM-5 Catalyst for Methane Dehydro-Aromatization in the Absence of Oxygen[刊, 中]/田丙伦(中科院大连化学物理所),徐奕德∥催化学报.&2000, 21(3).&255~258 国家重点基础研究发展规划项目 O643 01050217 热处理改性的活性炭纤维的脱硫活性=Desulfurization Activity of Activated Carbon Fiber Modified by Heat Treatment[刊, 中]/李开喜(中科院山西煤炭化学所),凌立成∥催化学报.&2000, 21(3).&264~268 考察了在O2和水蒸气存在下高温热处理对活性炭纤维(ACF)催化转化SO2为H2SO4的活性的影响,关联了ACF表面含氧官能团的种类及数量与其脱硫活性之间的关系.图4表2参20 国家自然科学基金(29633030)资助 O643 01050218 制备方法对锶改性氧化铝的高温热稳定性的影响=The Influence of Preparation Methods on the Thermal Stability of Alumina Modified by Strontium[刊, 中]/刘勇(复旦大学),陈晓银∥催化学报.&2000, 21(3).&273~275 福特-中国研究与发展基金资助 O643 01050219 NO在氧化铝负载的Pd催化剂上吸附的TPD-MS研究=TPD-MS Study of NO Adsorption on Alumina Supported Pd Catalysts[刊, 中]/刘振林(中国科技大学),伏义路∥催化学报.&2000, 21(3).&279~282 福特-中国研究与发基金资助项目 O643 01050220 不同焙烧气氛对氟化镁表面碱性的影响=The Effect of Different Calcination Atmosphere on the Surface Basicity of Magnesium Oxide[刊, 中]/孟明(中国科技大学),林培琰∥催化学报.&2000, 21(3).&286~288 在不同气氛中600℃下焙烧Mg(OH)2制得了MgO样品.结果表明,Mg(OH)2经焙烧后分解为MgO.样品的比表面积受焙烧气氛的影响,真空中制备的样品比表面积最大,而空气中制备的样品比表面积最小.真空中制备的样品具有最多的碱位和最强的碱性.图3表2参8 国家自然科学基金(29973037)资助 O643 01050221 Ni改性Cu/Mn/ZrO2催化剂上合成低碳混合醇的研究=Synthesis of Mixed Higher Alcohols by CO Hydrogenation over Ni-Modified Cu/Mn/ZrO2 Catalyst[刊, 中]/陈小平(中科院山西煤炭化学所),吴贵升∥催化学报.&2000, 21(4).&301~304 国家自然科学基金(29873064)资助 O643 01050222 超细镍基催化剂上CH4-CO2重整反应的性能:Ⅱ.制备方法对催化和抗积碳性能的影响=CH4 Reforming with CO2 over Superfine Ni-Based Catalysts:Ⅱ.Effects of Preparation Methods on Reactivity and Carbon Deposition over Catalysts[刊, 中]/许峥(清华大学),张鎏∥催化学报.&2000, 21(4).&309~313 国家博士点基金资助 O643 01050223 合成甲基叔丁基醚的分子筛催化剂研究=A Study of Zeolite Catalysts for Synthesis of Methyl tert-Butyl Ether[刊, 中]/李永红(天津大学),王莅∥催化学报.&2000, 21(4).&323~326 中国石油化工集团公司资助 O643 01050224 二苯并噻吩在CoMoNx催化剂上的加氢脱硫=Hydrodesulfurization of Dibenzothiophene over Cobalt-Promoted Molybdenum Nitride Catalysts[刊, 中]/柳云骐(石油大学),刘晨光∥催化学报.&2000, 21(4).&337~340 中国石油天然气集团公司资助 O643 01050225 锆助剂含量对钴基费-托合成催化剂的影响=Effect of ZrO2 Loadings on Catalytic Performance of Co/SiO2 for F-T Synthesis[刊, 中]/陈建刚(中科院山西煤炭化学所),相宏伟∥催化学报.&2000, 21(4).&359~362 国家重点基础研究发展规划项目 O643 01050226 一种天然气直接转化制乙烯的新过程=A Novel Process for Direct Conversion of Natural Gas to Ethylene[刊, 英]/朱爱民(中科院大连化物所),田志坚∥催化学报.&2000, 21(4).&395~396 国家科技部资助项目 O643 01050227 N,N-二甲基胺乙基膦酸-磷酸氢锆为载体的新型固体碱研究=Study on Solid Base Supported on Zirconium Dimethyl Aminoethylphosphonate-Phosphate[刊, 中]/龚成斌(中科院大连化学物理所),曾仁权…∥应用化学.&2000, 17(3).&264~267 国家自然科学基金资助 O643 01050228 丙烷在钒-磷混合氧化物催化剂上晶格氧氧化及其循环流化床工艺=Oxidation of Propane over Vanadium-Phosphorus Oxides Catalyst by Lattice Oxygen and Its Circulating Fluidized Bed Process[刊, 中]/王鉴(浙江大学),赵如松…∥应用化学.&2000, 17(3).&313~315 用脉冲色谱研究了丙烷在钒-磷混合氧化物催化剂上的选择氧化反应,并结合TPD和XRD表征结果,证明丙烷是与催化剂的晶格氧反应生成丙烯酸和乙酸.图2参5 国家自然科学基金(29676007)资助 O643 01050229 用以分解氟里昂-12的新型催化剂WO3/Al2O3=A Novel Catalyst WO3/Al2O3 for Decomposition of CFC-12[刊, 中]/马臻(复旦大学),华伟明…∥应用化学.&2000, 17(3).&319~321 国家科委攀登计划资助 O643 01050230 LaFeO3的光催化性=Photocatalytic Activity of LaFeO3[刊, 中]/白树林(天津大学),付希贤…∥应用化学.&2000, 17(3).&343~345 采用柠檬酸法和微乳液法制备纳米晶LaFeO3.结果表明,微乳液法较柠檬酸法制备的LaFeO3粒径小,表面积大,使LaFeO3吸附性增加,因此表现出较强的光催化活性.图2表1 国家自然科学基金(59772019)资助 O643 01050231 NiO/SiO2催化剂上CO氧化的反应机理研究=Mechanism of CO Oxidation on NiO/SiO2 Catalyst[刊, 中]/王远洋(宁夏大学),高荫本…∥宁夏大学学报(自然科学版).&2000, 21(2).&147~149 NiO/SiO2是优良的非贵金属型CO氧化催化剂,EXAFS和TPR表征表明其活性中心为NiO.在此基础上的Monte Carlo模拟表明,在NiO/SiO2上CO氧化遵循L-H机理.图5参11 国家自然科学基金(29803009)资助 O643 01050232 烯基取代的茂钛族络合物合成及应用于烯烃催化聚合的进展=Recent Advances in the Synthesis of Alkenyl Substituted Metallocene Complexes(Ti,Zr,Hf) and the Application of Its to α-Olefins Polymerization[刊, 中]/钱贤苗(华东理工大学),许胜…∥功能高分子学报.&2000, 13(3).&358~366 综述了含烯基取代基的茂钛族络合物的合成,取代基上双键的化学反应,以及在α-烯烃催化聚合上的最新进展.表2参45 国家自然科学基金(29871010)资助 O643 01050233 氧化态Co/γ-Al2O3催化剂的结构与反应性能研究:Ⅱ.钴物种微观结构的XAFS表征=Studies on the Structures and Catalytic Properties of Oxidized Co/γ-Al2O3 Catalysts:Ⅱ.XAFS Characterizations of the Micro-Structures of Co Species[刊, 中]/孟明(中国科学技术大学),林培琰…∥分子催化.&2000, 14(3).&161~165 采用X-射线吸收近边结构与扩展X-射线吸收精细结构技术,对用不同原料盐和不同焙烧温度制得的Co/γ-Al2O3催化剂中钴的微观结构进行了详细的表征.图5表1参8 国家自然科学基金(29973037)资助 O643 01050234 CuCl/γ-Al2O3上NO脱除过程研究=Reaction Mechanism of NO Conversion over CuCl/γ-Al2O3[刊, 中]/朱月香(北京大学),尉继英…∥分子催化.&2000, 14(3).&166~170 设计了一系列的对比实验,利用XRD、XPS、TPR、EXAFS等技术,系统研究了CuCl/γ-Al2O3上的NO脱除反应过程.图4表1参8 国家自然科学基金(29733080)资助 O643 01050235 以Au(PPh3)(NO3)为前体的Au/NiO催化剂的制备及其对CO的催化氧化=Preparation and Catalytic Performance of Au/NiO Catalyst Derived from Au(PPh3)(NO3) for CO Oxidation[刊, 中]/邹旭华(烟台大学),齐世学…∥分子催化.&2000, 14(3).&171~174 采用有机金属配合物固载法,将金的有机配合物Au(PPh3)(NO3)沉积于刚制备出的Ni(OH)2沉淀上.结果表明,以K2CO3作为制备Ni(OH)2的沉淀剂,金担载量为3%(质量分数)在焙烧温度为300℃的条件下,制备出的负载型金催化剂Au/NiO对CO的低温氧化有很高的催化活性.图2表3参15 国家自然科学基金(29873041)资助 O643 01050236 CexZr1-xO2复合氧化物负载PdO催化剂的CO和CH4氧化性能研究=CO and Methane Oxidation over CexZr1-xO2 Mixed Oxide Supported PdO Catalysts[刊, 中]/马磊(浙江大学),韩立峰…∥分子催化.&2000, 14(3).&175~178 浙江省自然科学基金资助 O643 01050237 溶胶-凝胶法镍基催化剂的研究&&Ti/Si原子比对NiO-TiO2-SiO2结构和苯加氢性能的影响=Study of the Nickel Catalysts Prepared by Sol-Gel Method&&The Effects of Si/Ti Atomic Ratios on the Structure and Catalytic Performance for Benzene Hydrogenation of NiO/TiO2-SiO2[刊, 中]/朱毅青(江苏石油化工学院),林西平…∥分子催化.&2000, 14(3).&184~190 中石化集团公司资助课题 O643 01050238 (NH4)15[La(PMo9V2O39)2]*6H2O杂多配合物对苯酚羟化的催化作用=Catalytic Activity of (NH4)15[La(PMo9V2O39)2]*6H2O Heteropoly Complex in Phenol Hydroxylation with Hydrogen Peroxide[刊, 中]/林深(福建师范大学),郑瑛…∥分子催化.&2000, 14(3).&191~194 福建省科委资助项目 O643 01050239 Co改性Mo/HZSM-5催化剂上甲烷无氧芳构化反应研究=Methane Dehydro-Aromatization over Cobalt Modified Mo/HZSM-5 Catalysts in the Absence of Oxygen[刊, 中]/田丙伦(中科院大连化学物理所),刘红梅…∥分子催化.&2000, 14(3).&200~204 国家重点基础研究发展规划项目 O643 01050240 甲醇催化氧化重整反应制氢的研究=Hydrogen Production by Catalytic Oxidation and Reforming of Methanol[刊, 中]/陈兵(华南理工大学),董新法…∥分子催化.&2000, 14(3).&205~208 广东省高教厅自然科学基金资助 O643 01050241 TiO2催化Cr(Ⅵ)-氯代苯酚共存体系中Cr(Ⅵ)的光致还原=Photo-Induced Cr(Ⅵ) Reduction in Cr(Ⅵ)-4CP Coexist Pollution System in the Presence of TiO2 Photocatalyst[刊, 中]/付宏祥(中科院兰州化学物理所),吕功煊…∥分子催化.&2000, 14(3).&214~218 中科院重大项目资助 O643 01050242 三磺化三苯基膦(TPPTS)制备方法的改进=Improvement of Synthesis Method of TPPTS[刊, 中]/张敬畅(北京化工大学),曹维良…∥分子催化.&2000, 14(3).&223~226 国家"九五”科技攻关项目 O644 01050243 预处理对TiO2表面超亲水性的影响=Effect of Pretreatment on Superhydrophilicity of TiO2 Films[刊, 中]/管自生(中科院化学所),马颖∥感光科学与光化学.&2000, 18(3).&204~207 在高温度环境下,应用紫外光辐射对溶胶-凝胶TiO2薄膜预处理,经过预处理的薄膜烧结后具有快速光致高度亲水特性和良好的光催化活性.超亲水的薄膜能够吸附大量的酸性品红,在光照下薄膜将吸附的酸性品红逐渐降解掉.图3参6 国家自然科学基金(59932040)重点资助 O644 01050244 荧光探针在测定N-异丙基丙烯酰胺共聚物最低临界溶液温度(LCST)时的扩散过程=The Diffusion Process of Fluorescence Probe in Measurement of LCST of Poly(N-Isopropylacrylamide-co-Acrylamide) Aqueous Solution[刊, 中]/李俊(中科院感光化学所),史向阳∥感光科学与光化学.&2000, 18(3).&208~213 合成了多种不同配比的N-异丙基丙烯酰胺(NIPAM)与丙烯酰胺(AM)的共聚物.研究了共聚物溶液在温度变化过程中发生的线团-胶粒转变,及荧光探针分子扩散进入疏水胶粒的动力学过程.图3表2参9 国家自然科学基金(29733100)资助 O644 01050245 蒽醌冠醚铕离子络合物分子内能量转移=Intramolecular Energy Transfer in Anthraquione Crown Ether-Eu3+ Complex[刊, 中]/江华(中科院感光化学所),许慧君∥感光科学与光化学.&2000, 18(3).&223~228 研究结果表明,选择性激发铕离子络合物中的蒽醌冠醚能发生分子内能量转移,观察到铕离子的发光.荧光衰减测试表明,由于冠醚的包络作用使得铕离子络合物的荧光寿命较未络合铕离子的寿命有所延长.图5表1参10 国家自然科学基金(29733100)资助 O644 01050246 有机染料光褪色机理及主要原因=The Mechanism and Main Reasons of Photofading of Organic Dyes[刊, 中]/于新瑞(大连理工大学),张淑芬∥感光科学与光化学.&2000, 18(3).&243~253 综述了有机染料光褪色机理的主要研究方法以及现有研究结论.对光氧化和光还原过程、影响因素、典型反应步聚、研究手段进行了系统的阐述,同时也对通过染料分子结构设计合成、通过添加剂的使用提高染料光牢度的方法进行了介绍.图4表3参29 国家自然科学基金重点基金(29836150)资助 O644 01050247 荧光分子开关的研究进展=The Progress of the Research on Fluorescent Molecular Switches[刊, 中]/甘家安(华东理工大学),陈孔常∥感光科学与光化学.&2000, 18(3).&254~262 根据开关动作完成的方式对近年来研究的各类荧光分子开关进行了简要的归类总结,并介绍了一些具有特殊功能的荧光分子开关器件.图8参33 国家自然科学基金(29836150)资助 O644 01050248 半花菁衍生物LB膜的光致荧光特性研究=Photoluminescence Characteristics of Hemicyanine Derivatives in Langmuir Blodgett Multilayers[刊, 中]/王文军(复旦大学),陆兴泽…∥物理化学学报.&2000, 16(6).&496~500 通过改变半花菁的亲水基团与硫水基团而得到了四种半花菁衍生物,利用稳态和时间分辨荧光研究了不同亲水基团与疏水基团对半花菁衍生物光学特性的影响.图1表3参7 国家自然科学基金重点基金(19834030)资助 O644 01050249 N-萘甲基多乙撑多胺类荧光化学敏感器=Fluorescence Chemical Sensor of Naphthylmethyl Polyethylenepolyamine[刊, 中]/梅明华(中科院感光化学所),吴世康∥物理化学学报.&2000, 16(6).&559~562 合成了一类带有萘甲基的多乙撑多胺化合物,对其在不同溶剂中作为FCS检测锌离子时的荧光光谱变化进行了研究.结果表明,两种不同锌盐化合物与配体相互作用时,其所带阴离子对络合物的组成和方式有很大的影响.图2表1参6 国家自然科学基金(29733100)资助 O644 01050250 三聚氰胺甲醛树脂的光学性质=Optical Properties of Melamine Formaldehyde Resin[刊, 中]/刘海波(复旦大学),侯占佳…∥物理化学学报.&2000, 16(6).&563~567 对三聚氰胺甲醛树脂的合成过程、波导制备条件及利用三聚氰胺甲醛树脂作为掺杂基质的非线性光学性质进行了研究.实验结果表明,三聚氰胺甲醛树脂是一种极具有应用前景的光学材料.图3参14 国家自然科学基金(69708005,69808001)资助 O644 01050251 紫菜两个光系统间激发能分配研究对光合进化的启示[刊, 中]/潘洁(中科院化学所),施定基…∥科学通报.&2000, 45(12).&1276~1279 选择两个不同发育阶段(孢子体和配子体)的条斑紫菜作为研究对象.对过多激发能在两个光系统间的分配进行了比较研究.图2参13 国家自然科学基金(39890390,29733100)资助 O644 01050252 非线性光学配合物的化学研究[刊, 中]/左景林(南京大学),游效曾∥科学通报.&2000, 45(14).&1457~1464 从化学角度出发,在分子水平上研究和探索新型分子基非线性光学材料是一个新的研究领域.总结了近年来在新型二阶、三阶极化率和光限制等非线性光学配合物的化学研究方面所取得的进展.图6表2参46 国家自然科学基金(29631040)资助 O644 01050253 螺旋共轭化合物1′,3′,3′-三甲基-6-羟基螺旋[2H-1-苯并吡喃-2,2′-二氢吲哚]的结构、光谱、非线性光学性质和光异构化过程的理论研究=Theoretical Study of the Structures, Spectra, Nonlinear Second-Order Optical Properties and Photoisomerization Process of the Spiroconjugated Compound 1′,3′,3′-Trimethyl-6-Hydroxyspiro[2H-1-Benzopyran-2,2′-Indoline][刊, 中]/孙秀云(吉林大学),封继康…∥高等学校化学学报.&2000, 21(7).&1080~1085 用AM1和ZINDO方法研究了螺旋共轭化合物1′,3′,3′-三甲基-6-羟基螺旋[2H-1-苯并吡喃-2,2′-二氢吲哚](HBPS)及其光导构化产物的结构和光谱性质,从理论上研究了HBPS的光异构化反应过程,并在此基础上,用自编的完全态求和公式(SOS)程序计算了非线性光学系数.图4表7参17 国家自然科学基金(29873016)资助 O644 01050254 Af型自由基均聚反应的固化理论(Ⅲ)&&高分子凝胶网络缺陷=The Curing Theory of Af Type Free Radical Homopolymerization(Ⅲ)&&The Defects of Polymer Gel Network[刊, 中]/王海军(河北大学),赵敏…∥高等学校化学学报.&2000, 21(7).&1138~1141 应用高分子反应统计理论,分析了高分子网络的形成过程,讨论了Af型自由基均聚反应凝胶网络中的缺陷&&悬吊环的数目及其形成几率.图4参22 国家自然科学基金(29673018)资助 O646 01050255 微过氧化物酶-11修饰电极对O2和H2O2的电催化还原=Electrocatalytic Reduction of O2 and H2O2 at the Glass Carbon Electrode Modified with Microperoxidase-11[刊, 中]/杨辉(南京师范大学),黄志忠…∥物理化学学报.&2000, 16(6).&527~532 运用电化学循环伏安法和旋转圆盘电极技术研究了O2和H2O2在Nafion膜固定的微过氧化物酶-11修饰的玻碳电极上的电化学还原.图6参16 国家自然科学基金资助 O646 01050256 电沉积Co-Cu颗粒膜的巨磁电阻效应=Giant Magnetoresistance in Electro-Deposited Co-Cu Granular Film[刊, 中]/李浩华(兰州大学),黎超…∥物理化学学报.&2000, 16(6).&573~576 用电化学沉积法制备了Co-Cu纳米颗粒膜,并对这种膜的结构、磁性、巨磁电阻效应作了较详细的研究.图6参7 国家自然科学基金资助 O646 01050257 磷酸溶液中铝恒压阳极氧化的研究=Investigation of Aluminum Anodizing in Phosphoric Acid Solution at Constant Voltage[刊, 中]/王为(天津大学),郭鹤桐…∥天津大学学报.&2000, 33(3).&341~343 结果表明,随着电解电压的升高,形成的氧化铝多孔膜的阻挡层增厚,多孔层的孔径和胞径均增加,其原因与离子迁移等密切相关.图6参6 国家自然科学基金(69601006)资助 O646 01050258 二次微分简易示波伏安法测定痕量镍=Determination of Trace Nickel by Second-Order Differential Simple Oscillographic Voltammetry[刊, 中]/傅业伟(西北大学),高敏…∥应用化学.&2000, 17(3).&296~299 国家自然科学基金(29775018)资助 O646 01050259 Ml(NiCuAlZn)5储氢合金粉末的包覆处理=Encapsulation of Ml(NiCuAlZn)5 Hydrogen Storage Alloy Powder[刊, 中]/王一菁(南开大学),赵东…∥应用化学.&2000, 17(3).&310~312 国家"八六三”计划资助项目 O646 01050260 和厚朴酚电化学还原机理的研究=Theoretical Study on the Mechanism of Electrochemical Reductions Reaction of Honokiol[刊, 中]/孙成科(曲靖师范高等专科学校),龚思源…∥高等学校化学学报.&2000, 21(6).&912~917 用量子化学AM1、PM3方法研究了和厚朴酚分子的电化学还原反应机理.结果表明,和厚朴酚分子电还原的基团为两个烯丙基的双键,其中邻位烯丙基优先被还原,对位次之,整个还原反应中和厚朴酚得到4e和4H+,使两个烯丙基饱和,计算结果较好地说明了实验事实.图2表7参12 国家自然科学基金(29773007)资助 O646 01050261 Fourier自去卷积示波计时电位法的研究=Oscillographic Chronopotentiometry with Fourier Self-Deconvolution[刊, 中]/郑建斌(西北大学),张红权…∥高等学校化学学报.&2000, 21(7).&1037~1039 国家自然科学基金(29775018)资助 O646 01050262 用规整膜板对砷化镓的三维微结构图形加工刻蚀=Three-Dimensional Microfabrication on GaAs Using a Regular Patterns Mold[刊, 中]/董海苟(厦门大学),孙建军…∥电化学.&2000, 6(3).&253~257 以微齿轮图形结构作为规整模板.用约束刻蚀剂层技术对GaAs样品表面进行了加工刻蚀.在有捕捉剂H3AsO3存在的情况下,规则微齿轮图形能够很好地在样品表面复制.图5参6 国家自然科学基金重点项目(29833070)资助 O646 01050263 混凝土中钢筋的腐蚀行为研究=Corrosion Behavior of Reinforcing Steel in Concrete[刊, 中]/林荣归(厦门大学),胡融刚…∥电化学.&2000, 6(3).&305~310 钢筋在混凝土中受到高碱性环境的保护,耐蚀性好,但随着介质pH的降低、Cl-含量的上升,钢筋腐蚀电流升高;动电位阳极极化曲线的测试表明,钢筋的维钝电流增大,击穿电位负移,混凝土中钢筋的耐蚀性下降.图4表1参6 国家自然科学基金(59871043)资助 O647 01050264 天冬氨酸在Cu(001)表面吸附的扫描隧道显微镜研究=Adsorption of Aspartic Acid on Cu(001) Studied by Scanning Tunneling Microscopy[刊, 中]/王浩(北京大学),赵学应…∥物理学报.&2000, 49(7).&1316~1320 国家自然科学基金(19634010)资助 O647 01050265 共聚高分子吸附的Monte Carlo模拟=Monta Carlo Simulation of Adsorption of Diblock Copolymer at Solid-Liquid Interface[刊, 中]/陈霆(华东理工大学),刘洪来…∥化工学报.&2000, 51(4).&512~518 用Monte Carlo方法对选择性溶剂中两嵌段共聚高分子在固液界面的吸附进行了模拟,获得了吸附等温线以及吸附层厚度、链附着率、表面覆盖率、链节浓度分布等表征吸附层结构的信息,同时模拟获得了固液界面区吸附构型大小及分布等表征高分子构型的微观信息.图12表1参10 国家自然科学基金(29736170)资助 O647 01050266 无规共聚高分子溶液相平衡的Monte Carlo模拟=Monte Carlo Simulations of Phase Equilibria of Random Copolymer Solutions[刊, 中]/陈霆(华东理工大学),刘洪来…∥化工学报.&2000, 51(4).&552~554 用构型偏倚蒸发Monte Carlo方法模拟研究了密堆积格子模型上A、B无规共聚高分子的相平衡问题,无规共聚高分子中链节A、B以不同的相互作用能来区别.模拟获得了链长直至200个链节的无规共聚高分子系统相平衡数据,同时计算获得了不同链长固定组成下无规共聚高分子系统相应的临界点.图2表1参12 国爱自然科学基金(29736170)资助 O648 01050267 Triton X-100/正癸醇/水层状液晶制备泡囊=Preparation of Vesicles from Lamellar Liquid Crystal in Triton X-100/n-C10H21OH/H2O System[刊, 中]/丁元华(扬州大学),刘天晴…∥物理化学学报.&2000, 16(6).&481~486 以Triton X-100/n-C10H21OH/H2O体系生成的层状液晶为介质制备泡囊,所得泡囊分布比较均匀,囊径在0.2~0.5 μm之间.研究了层状液晶组成、pH、超声振荡时间等因素对所制泡囊的电位及微极性的影响.图6表2参16 国家自然科学基金(29673035)资助 O648 01050268 表面波技术研究TBP对C12E8表面流变性质的影响=Influence of TBP on the Surface Rheological Properties of C12E8 Studied by Surface Wave Method[刊, 中]/韩国彬(厦门大学),吴金添…∥物理化学学报.&2000, 16(6).&507~511 利用表面波技术研究消泡剂TBP对起泡剂C12E8表面流变性质的影响,阐述泡沫的排液过程中液膜变形所产生的表面张力梯度修复机理以及液膜强度与表面膨胀模量、表面膨胀弹性和表面膨胀粘度的关系,并且探讨了消泡剂TBP的消泡机理.图4参6 国家自然科学基金(29973033)资助 O648 01050269 制备宽温区O/W微乳的新方法=Novel Method to Prepare O/W Microemulsions within a Wide Temperature Range[刊, 英]/梁文平(中科院化学所),Tharwat F Tadros∥物理化学学报.&2000, 16(6).&538~542 通过把一个带有羧基的离子表面活性剂镶嵌在微乳界面的单分子层中,在低pH值时,形成水包油微乳,然后用氢氧化钠中和使其表面离子化而形成一个较厚的双电层,从而得到的宽温区(0-90℃)水包油微乳.研究了油相浓度、pH以及微乳液滴的大小对体系的浊点的影响.图5参12 国家自然科学基金资助 O65 01050270 Triton X-100与牛血清白蛋白的相互作用=The Interaction between Triton X-100 and Bovine Serum Albumin[刊, 中]/魏晓芳(中科院化工冶金所),刘会洲∥分析化学.&2000, 28(6).&699~701 国家自然科学基金重点项目资助 O65 01050271 球形铜离子模板缩聚物的制备及其选择吸附性能=The Preparation of Globular Copper(Ⅱ) Template Condensation Polymer and Its Behavior of the Selective Adsorption[刊, 中]/王旭东(南开大学),何锡文…∥分析化学.&2000, 28(7).&805~809 以苯酚、甲醛、四乙烯五胺为反应单体,铜离子为模板,反相悬浮聚合制备出球形离子模板缩聚物.该模板缩聚物对铜离子的吸附性能显著优于相应的非模板缩聚物.图6参3 国家自然科学基金(29775011)资助 O65 01050272 杯芳烃银离子敏感场效应晶体管传感器=Silver Ion-Sensitive Field-Effect Transistor Based on Calixarene[刊, 中]/陈朗星(南开大学),牛文成…∥分析化学.&2000, 28(7).&815~819 报道了硫醚取代的杯[4]芳烃化合物的合成,以此化合物为敏感材料,研制了聚氯乙烯膜的银离子敏感场效应晶体管(Ag+-ISFET)传感器.Ag+-ISFET传感器对银离子表现出优良的能斯特响应,该传感器对碱金属、碱土金属及过渡金属离子有极高的选择性.图5表1参13 国家自然科学基金(29975014)资助 O65 01050273 电极扩散层内物质浓度及分布研究方法进展=Development of Research Method of Concentration Observation and Distribution in Electrode Diffusion Layer[刊, 中]/杨玉书(重庆大学),夏之宁…∥分析化学.&2000, 28(7).&897~903 评述了测试电极扩散层内物质浓度及分布的各种方法,分别从方法原理、实验装置、影响因素及其应用等方面加以论述,评价了各种方法的特点,并对发展方向进行了展望.参52 国家自然科学基金(29775035)资助 O657 01050274 甲烷氧化偶联Na-W-Mn/SiO2催化剂的喇曼光谱=Raman Spectroscopy Characterization of Na-W-Mn/SiO2 Catalyst for Oxidative Coupling of Methane[刊, 中]/陈宏善(中科院兰州化学物理所),牛建中…∥物理化学学报.&2000, 16(6).&543~546 研究了A16061/SiCp复合材料表面双层稀土转化膜的微观结构以及化学组成,并对稀土转化膜对抗腐蚀性能进行了评估.结果表明,稀土转化膜能显著提高耐蚀性.图2表3参10 国家自然科学基金资助 O657 01050275 12-钼磷酸-葡聚糖包合物的研究=Study on the Inclusion Compound of 12-Molybdenum Phosphoric Acid with Dextran[刊, 中]/程贤C026(福建师范大学),苏英草…∥物理化学学报.&2000, 16(7).&658~662 福建省教委基金资助 O657 01050276 O/W微乳液中制备甲基丙烯甲酯-苯乙烯共聚物超细颗粒=Preparation of Methyl Methacrylate and Styrene Copolymer Ultrafine Particles in the Oil-in-Water Microemulsions[刊, 中]/钱君律(同济大学),甘礼华…∥同济大学学报(自然科学版).&2000, 28(3).&320~323 在甲基丙烯酸甲酯(MMA)-苯乙烯-环己烷/十六烷基三甲基溴化铵/水体系的O/W微乳液中,制备了粒径约58 nm球状甲基丙烯酸甲酯-苯乙烯共聚物超细颗粒.研究了影响粒子形态和大小的因素.图4表1参12 国家自然科学基金(29673030)资助 O657 01050277 基于小波神经网络的新型算法用于化学信号处理=A Novel Algorithm Based on the Wavelet Neural Network for Processing Chemical Signals[刊, 中]/蔡文生(中国科技大学),于芳…∥高等学校化学学报.&2000, 21(6).&855~859 基于紧支集正交小波神经网络的构造思想,用具有紧支集的B-样条函数的伸缩和平移替代小波函数,提出了一种新型算法,并将其应用于化学信号的处理,实现了信号的压缩和滤噪,与自适应小波神经网络相比,学习速度得到了大幅度的提高.图4表2参9 国家自然科学基金(29775001)资助 O657 01050278 改进溶胶-凝胶法固定酶结构剖析及在苯酚光化学传感器中的应用=The Microstructure Analysis of Enzymes Immobilized by Sol-Gel Method and Its Application in Phenol Optical Chemical Sensor[刊, 中]/李军(湖南大学),王柯敏…∥高等学校化学学报.&2000, 21(7).&1018~1022 结果表明,酶固定于溶胶-凝胶中后,与在溶液中一样,呈均匀分布且不易流失.此敏感膜可用于制备基于化学发光强度减弱的苯酚光化学传感器;用竞争反应的原理讨论了响应机理.图3表1参20 国家自然科学基金(29675005)及国家杰出青年基金(29825110)资助 O657 01050279 一种用于电热蒸发-原子光谱的微型化固相萃取技术=A Miniaturization Solid-Phase Extraction Technique Designed for Electrothermal Vaporization-Atomic Emission Spectrometry Determination[刊, 中]/熊宏春(武汉大学),胡斌…∥高等学校化学学报.&2000, 21(7).&1035~1036 国家自然科学基金(29875022)资助 O657 01050280 多环芳烃芴、苊的无保护流体室温磷光性质研究=Studies on Non-Protected Fluid Room Temperature Phosphorescence of Polycyclic Aromatic Hydrocarbon of Fluoren and Acenaphthene[刊, 中]/李隆弟(清华大学),牟兰…∥高等学校化学学报.&2000, 21(7).&1040~1042 国家自然科学基金(29775013)资助 O657 01050281 高效液相色谱/大气压化学电离质谱快速分析水中痕量有机磷农药=Rapid Analysis of Trace Organophosphorous Pesticides in Water by High Performance Liquid Chromatography/Atmospheric Pressure Chemical Ionization Mass Spectrometry[刊, 中]/潘元海(中科院生态环境研究中心),金军…∥分析化学.&2000, 28(6).&661~671 用反相液谱短柱实现了6种有机磷农药(乙酰甲胺磷,甲基对硫磷、杀螟硫磷、喹硫磷、二嗪农、辛硫磷)的高效液相色谱/大气压化学电离质谱(HPLC/APCIMS)快速分析.此技术可以很好地实现水中痕量有机磷农药的测定,一次联机分析仅需10 min.图3表2参11 国家自然科学基金(29977023)资助 O657 01050282 氧氟沙星对映体的同步-导数荧光光谱法识别与测定=Recognition and Determination of Ofloxacin Enantiomers by Synchronization-Derivative Fluorimetry[刊, 中]/弓巧娟(山西大学),晋卫军…∥分析化学.&2000, 28(6).&672~677 控制pH=3,首次通过同步一阶导数荧光光谱技术,有效地识别和分辨氧氟沙星的R和S对映体,同时有效地消除尿样背景的干扰.据此建立了同时识别与测定两种旋光体的同步-导数荧光光谱法.图5表2参9 国家自然科学基金(29875016)资助 O657 01050283 一种新的重原子微扰剂氯代叔丁烷在亚硫酸钠化学除氧环糊精诱导室温磷光法中的应用研究=A Study of t-Butyl Chloride as Heavy Atom Perturber in Chemical Deoxygenation-Cyclodextrin Induced Room Temperature Phosphorimetry[刊, 中]/张淑珍(山西大学),魏雁声…∥分析化学.&2000, 28(6).&678~681 以氯代叔丁烷作重原子微扰剂采用亚硫酸钠化学除氧技术建立了菲、7,8-苯并喹啉、2-溴代萘在环糊精介质中的室温磷光分析法.图4表2参5 国家自然科学基金(29575204)资助 O657 01050284 小牛胸腺脱氧核糖核酸诱导中性红聚集的机理及其影响因素=The Aggregation of Neutral Red Encouraged by Deoxyribonucleic Acids and Its Depending Factors[刊, 中]/黄新华(西南师范大学),李原芳…∥分析化学.&2000, 28(6).&682~686 在pH7.6~7.8和低离子强度条件下,中性红与小牛脱氧核糖核酸(ctDNA)作用产生以535 nm为特征的共振光散射增强(ERLS)光谱.机理研究表明,这种ERLS是由于DNA诱导中性红的聚集所致.图6表1参11 国家自然科学基金(29875019)资助 O657 01050285 蛋白质样品的非竞争性毛细管电泳免疫分析激光诱导荧光检测=Noncompetitive Capillary Electrophoresis Based Immunoassay for Proteins with Laser Induced Fluorescence Detection[刊, 中]/王清刚(清华大学),罗国安…∥分析化学.&2000, 28(6).&687~691 国家自然科学基金重点资助 O657 01050286 亲和毛细管电泳测定孕酮与其单克隆抗体的结合常数=Determination of the Binding Constant between Progesterone and Its Monoclonal Antibody Using Affinity Capillary Electrophoresis[刊, 中]/王清刚(清华大学),王义明…∥分析化学.&2000, 28(6).&731~734 采用亲和毛细管电泳的配体分离模式,以激光诱导荧光作为检测手段,测定了荧光素标记的孕酮与孕酮单克隆抗体之间的结合常数,并研究了温育时间、电泳条件等因素对测定的影响.图3参5 国家自然科学基金重点资助 O657 01050287 钌(Ⅱ)-联吡啶-铈(Ⅳ)-戊二醛化学发光体系及其应用=Chemiluminescence System of Ru(bpy)2+3-Ce(Ⅳ)-Glutaraldehyde and Its Application[刊, 中]/韩鹤友(武汉大学),何治柯…∥分析化学.&2000, 28(6).&738~740 基于在硫酸介质中戊二醛增强铈(Ⅳ)氧化钌(Ⅱ)-联吡啶的化学发光强度.在优化后的条件下,方法的线性范围和检测限分别为2.5×10-6~2.5×10-3 mol/L和3.1×10-7 mol/L戊二醛.图1表1参6 国家自然科学基金(29605001)资助 O657 01050288 毛细管区带电泳法测定甲氧苄胺嘧啶和磺胺甲基异C023唑的离解常数及其在复方新诺明中的含量=Determination of Dissociation Constants of Trimethoprim and Sulfamethoxazole and Their concentrations in Co-Trimoxazole Tablets by Capillary Zone Electrophoresis[刊, 中]/李前锋(兰州大学),张红医…∥分析化学.&2000, 28(7).&793~797 国家自然科学基金(29475194和29675007)资助 O657 01050289 联用色谱数据的半自动解析法=Semiautomatic Deconvolution of Hyphenated Chromatographic Data[刊, 中]/甘峰(湖南大学),李晓宁…∥分析化学.&2000, 28(7).&833~836 采用正交投影法获得初始迭代光谱,继采用非负最小二乘法和常规最小二乘法进行交替迭代,最终获得纯光谱和纯色谱向量.图2参15 国家自然科学基金(29875007)资助 O657 01050290 陈皮挥发油的气相色谱/质谱分析=Determination of the Volatile Oil of Pericarpium Citri Reticulatae with Gas Chromatography/Mass Spectrometry[刊, 中]/龚范(湖南大学),梁逸曾…∥分析化学.&2000, 28(7).&860~864 用GC/MS分析复方制剂平胃散中的一种单味药材陈皮的挥发油化学成分及其相对含量.分离出53个组分,其中鉴定了34个组分,约占其挥发油总量的96.08%.图5表1参7 国家自然科学基金(29875007)资助 657 01050291 人工神经网络法鉴别红外光谱=Artificial Neural Network for the Identification of Infrared Spectra[刊, 中]/李燕(南京理工大学),王俊德…∥光谱学与光谱分析.&2000, 20(4).&477~479 将反向传播人工神经网络用于FTIR,鉴别未知化合物.结果表明,当训练集样本不含噪声时,纯光谱的预测结果很好.而当训练集样本有少量噪声干扰时,预测结果随预测集样本的不同,而得到了不同的改善.图3参6 国家自然科学基金资助 O657 01050292 苯丙氨酸桥联金属双卟啉的诱导圆二色光谱研究=The Study of Induced Circular Dichroism of Phenylalanine Bridged Metal Bis-Porphyrin[刊, 中]/刘海洋(华南理工大学),黄锦汪…∥光谱学与光谱分析.&2000, 20(4).&495~497 报道了邻位和对位桥联苯丙氨酸锌双卟啉的合成,考查了双卟啉的分子结构对诱导圆二色性的影响.结果表明,两个卟啉环之间的π-π堆积和手性激子偶合作用是影响此类双卟啉圆二色光谱的主要因素.图3参16 国家自然科学基金(29771034)资助 O657 01050293 砷和汞的顺序注射-蒸气发生原子吸收光谱测定=Sequential Injection Vapor Generation Atomic Absorption Spectrometric Determination of Mercury and Arsenic[刊, 中]/马泓冰(东北大学),徐淑坤…∥光谱学与光谱分析.&2000, 20(4).&529~532 建立了砷和汞的顺序注射-蒸气发生原子吸收光谱测定方法.在流动注射蒸气发生原子吸收光谱测定方法的基础上,采用汇流技术,通过两个微量注射泵和一个多位选择阀的计算机程控操作,实现待测组分与硼氢化钠间的强氧化还原反应及其气-液分离过程.图3表4参4 国家自然科学基金资助 O657 01050294 氢化物的气相富集及其在超痕量分析中的应用=The Gaseous Phase Enrichment Techniques in Hydride Generation (Review)[刊, 中]/郭旭明(厦门大学),黄本立…∥光谱学与光谱分析.&2000, 20(4).&533~536 从富集原理及其在光谱超痕量分析的应用方面分别对这几种氢化物发生后的气相富集技术进行了较详细地综述.这些气相富集方法包括液氮冷却捕集技术、气球收集技术、石墨炉原位捕集技术、吸收液吸收技术及固体吸附技术等.参63 国家自然科学基金资助 O657 01050295 pH诱导牛血清白蛋白芳香氨基酸残基微环境变化的光谱分析=Spectral Study of the Microenviroment Change of Aromatic Amino-Acid Residues in BSA Induced by pH[刊, 中]/魏晓芳(中科院化工冶金所),刘会洲…∥光谱学与光谱分析.&2000, 20(4).&556~559 用荧光光谱和紫外吸收光谱研究了pH=2.3~11.3范围内牛血清白蛋白芳香氨基酸残基微环境的变化,以此推断蛋白质构象的变化,并讨论蛋白质表面疏水性变化的趋势.图4表1参8 国家自然科学基金重点基金资助 O657 01050296 传感器几何结构对近红外组织氧合检测仪灵敏度的影响=The Influence of Probe Geometry on the Sensitivity of Tissue Oximeter Using Near Infra-Red Spectroscopy[刊, 中]/王峰(清华大学),丁海曙…∥光谱学与光谱分析.&2000, 20(4).&585~588 利用蒙特卡罗仿真方法对光在多层生物组织模型中的平均穿透深度、光子平均飞行距离和空间灵敏度分布进行了仿真,结果表明,传感器几何结构,即光源与光检测器之间的距离是影响灵敏度的重要因素,适当增加这一距离有助于深层组织生化信息的提取和测量灵敏度的提高,但是它又受到信噪比降低的限制.图8参3 国家自然科学基金资助 O657 01050297 精密气动液压伺服系统用于傅里叶变换光谱仪光谱测量=Spectral Measuring of Fourier Transform Spectrometer Using Pneumatic Hydraulic Servo System[刊, 中]/李志刚(中科院长春光学精密机械所),王淑荣…∥光谱学与光谱分析.&2000, 20(4).&589~591 讨论了傅里叶变换光谱仪动镜稳定平移的重要性,研制了以高压无氧氮气为动力源的精密气动液压系统用于推进在研傅里叶变换光谱仪"猫眼”动镜系统,并在此基础上测量了ZYGO干涉仪光源光谱图.图4参5 国家自然科学基金资助 O658 01050298 超临界流体色谱法分离手性化合物的进展=Advances in Chiral Separations by Supercritical Fluid Chromatography[刊, 中]/任其龙(浙江大学),苏宝根…∥分析化学.&2000, 28(6).&772~776 国家自然科学基金(29776040)资助 O658 01050299 长江口水体混合过程中溶解态稀土元素分布特征[刊, 中]/王中良(中科院地球化学所),刘丛强∥科学通报.&2000, 45(12).&1322~1326 采用液-液萃取与反萃取分离富集方法和ICP-MS测试技术,对长江河口南支盐度0.15~19 mg/g表层水体中溶解态稀土元素的浓度进行了测定.图2表1参17 国家杰出青年科学基金(49625304)资助 O658 01050300 分子烙印手性固定相分离过程热力学研究=Thermodynamic Study on Separation of Molecular Imprinting Chiral Stationary Phase[刊, 中]/王进防(中科院大连化学物理所),周良模…∥高等学校化学学报.&2000, 21(6).&930~933 结果表明,分子烙印手性固定相的分离过程为焓控制过程.随着温度的升高,样品的容量因子降低,手性选择因子α减小.样品与分子烙印固定相的作用力包括非特异作用力和特异作用力,只有特异作用力的差值才是手性分离的本质.表2参22 国家自然科学基金(29575212)资助 O658 01050301 十八烷基醚型高效液相反相色谱填料的制备=Synthesis and Characterization of Ether-Bond RP-Packing[刊, 中]/喻昕(中科院化学所),赵睿…∥高等学校化学学报.&2000, 21(7).&1043~1044 国家自然科学基金(29635010)资助